natgillin/translations-raw huggingface dataset:
21.4 mg/ ml emodepside
smiselna
cap (PP)
zaporko
0.70 ml
1, 12 ml
80 pipettes
80 pipet
for large cats
kapljice za
Profender spot-on solution
Profender, kožne 85, 8 mg/ ml kapljice za prazikvantela & velike mačke 21, 4 mg/ ml emodepsida
for large cats
EU številka
praziquantel &
Izmišljeno ime
with screw
Farmacevtska
21.4 mg/ ml emodepside
Ciljna živalska
cap (PP)
Karenca
Profender spot-on solution
Profender, kožne 85, 8 mg/ ml kapljice za prazikvantela & mačke 21, 4 mg/ ml emodepsida
Bottle (glass)
Steklenica
dogs
za majhne pse prazikvantela & 3 mg emodepsida
mg emodepside
prirejenim sproščanje
tablets
uporaba
(Alu/ Alu)
(alu/ alu)
mg emodepside
za majhne pse prazikvantela & 3 mg emodepsida
Pharmaceutical
prirejenim sproščanje
Route of
uporaba
Packaging
(alu/ alu)
species
smiselna
10 mg emodepside
za srednje velike prazikvantela & pse 10 mg emodepsida
30 mg emodepside
za velike pse prazikvantela & 30 mg emodepsida
1 [Single-dose pipettes]
1 [Enoodmerna pipeta]
Profender spot-on solution for small cats Profender spot-on solution for medium cats Profender spot-on solution for large cats
Profender, kožni nanos, raztopina za majhne mačke Profender, kožni nanos, raztopina za srednje velike mačke Profender, kožni nanos, raztopina za velike mačke
Profender contains 21.4 mg/ ml emodepside and 85.8 mg/ ml praziquantel.
Profender vsebuje 21, 4 mg/ ml emodepsida in 85, 8 mg/ ml prazikvantela.
Each unit dose (pipette) of Profender delivers:
Enota odmerka (pipeta) pripravka Profender vsebuje:
Profender for Small Cats (≥ 0.5 - 2.5 kg)
Profender za majhne mačke (≥ 0, 5 – 2, 5 kg)
30 mg
30, 0 mg
Profender for Medium Cats (> 2.5 – 5 kg)
Profender za srednje velike mačke (> 2, 5 – 5 kg)
15 mg
15, 0 mg
60 mg
60, 0 mg
24 mg
24, 0 mg
96 mg
96, 0 mg
5.4 mg/ ml butylhydroxyanisole (E320; as antioxidant)
5, 4 mg/ ml butilhidroksianizol (E 320 kot antioksidant)
For cats suffering from, or at risk from, mixed parasitic infections caused by roundworms and tapeworms of the following species:
Za mačke, ki imajo ali so izpostavljene mešanim infekcijam z glistami in trakuljami:
Roundworms (Nematodes) Toxocara cati (mature adult, immature adult, L4 and L3) Toxascaris leonina (mature adult, immature adult and L4) Ancylostoma tubaeforme (mature adult, immature adult and L4)
Gliste (Nematodi) Toxocara cati (zrele, nezrele oblike, ličinke L4, L3) Toxascaris leonina (zrele, nezrele oblike, ličinke L4) Ancylostoma tubaeforme (zrele, nezrele oblike, ličinke L4)
2 Tapeworms (Cestodes) Dipylidium caninum (adult) Taenia taeniaeformis (adult) Echinococcus multilocularis (adult)
2 Echinococcus multilocularis (zrele oblike)
Do not use in kittens under 8 weeks of age or weighing less than 0.5 kg.
Zdravila ne dajemo mačjim mladičem mlajšim od 8 tednov in lažjim od 0, 5 kg.
Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.
Zajedavci lahko razvijejo odpornost proti antiparazitiku, ki ga pogosto uporabljamo.
There is limited experience on the use of the product in sick and debilitated animals, thus the product should only be used based on a benefit-risk assessment for these animals.
Zaradi pomanjkanja izkušenj z dajanjem zdravila bolnim in oslabljenim živalim, pri teh živalih zdravilo uporabimo le v skladu z oceno razmerja korist/ tveganje.
If skin or eye symptoms persist, or in case of accidental ingestion, seek medical advice and show the package leaflet or the label to the physician.
Pri zaužitju zdravila ali, če vzdraženje kože ali oči ne mine, poiščite zdravniško pomoč in pokažite navodilo za uporabo.
Frequent users of the product (for example, veterinarians, professional cat breeders) should wear disposable gloves when administering the product.
Osebe, ki zdravilo pogosto nanašajo (npr. veterinarji, vzreditelji mačk), naj pri nanašanju uporabljajo zaščitne rokavice za enkratno uporabo.
Although the product was well tolerated by pregnant cats, studies performed in rats and rabbits suggest that emodepside may interfere with embryo-foetal development.
Čeprav so breje mačke zdravilo dobro prenašale, so študije na podganah in kuncih pokazale, da lahko emodepsid vpliva na embrio- fetalni razvoj.
Therefore, women of child- bearing potential should avoid contact with, or wear disposable gloves when administering, the product.
Rodne ženske naj se izogibajo stiku z zdravilom ali pa uporabijo zaščitne rokavice za enkratno uporabo.
This is thought to occur as a result of the cat licking the application site immediately after treatment.
Če mačka takoj po nanosu poliže mesto nanosa, se zelo redko lahko pojavi slinjenje in bruhanje.
In very rare cases following administration of Profender transient alopecia, pruritus and/ or inflammation were observed at the application site.
V posameznih primerih se je po aplikaciji Profenderja na mestu nanosa pojavilo prehodno izpadanje dlak, pruritis in/ ali vnetje.
Emodepside is a substrate for P-glycoprotein.
Emodepsid je substrat za P- glikoprotein.
Co-treatment with other drugs that are P-glycoprotein substrates/ inhibitors (for example, ivermectin and other antiparasitic macrocyclic lactones, erythromycin, prednisolone and cyclosporine) could give rise to pharmacokinetic drug interactions.
Sočasno zdravljenje z zdravili, ki so substrati/ inhibitorji P - glikoproteinov (npr. ivermektin in drugi protiparazitarni makrociklični laktoni, eritromicin, prednizolon in ciklosporin) lahko povzroči farmakokinetične interakcije.
The recommended minimum doses are 3 mg emodepside / kg body weight and 12 mg praziquantel / kg body weight, equivalent to 0.14 ml Profender / kg body weight.
Najmanjši odmerek je 3, 0 mg emodepsida/ kg telesne mase ter 12, 0 mg prazikvantela / kg telesne mase, kar ustreza 0, 14 ml zdravila Profender/ kg telesne mase.
Body Weight of Cat (kg)
Telesna masa
Pipette size to be used
Vrsta pipete
Volume (ml)
Enota
Praziquantel (mg/ kg bw)
Prazikvantel
≥ 0.5 - 2.5 > 2.5 - 5 > 5 - 8
mačke (kg) ≥0, 5 – 2, 5
Profender for Small Cats Profender for Medium Cats Profender for Large Cats
Profender za srednje velike mačke Profender za velike mačke
0.35 0.70 1.12
0, 70 1, 12
3 - 15 3-6 3 - 4.8
3- 6 3 – 4, 8
12 - 60 12 - 24 12 - 19.2
12 - 24 12 – 19, 2
Use an appropriate combination of pipettes
Uporabite ustrezno kombinacijo pipet
A single administration per treatment is effective.
Zdravljenje je učinkovito že po enkratnem dajanju.
Hold pipette in upright position, twist and pull off cap and use the opposite end of the cap to break the seal.
Vzemite pipeto iz ovojnine, držite jo navpično, zavrtite in snemite zaporko, obrnite jo in prebodite plastično zaporo na pipeti.
Part the fur on the cat’ s neck at the base of the skull until the skin is visible.
Mački razmaknite dlako na zatilju, da bo vidna koža.
Place the tip of the pipette on the skin and squeeze firmly several times to empty the contents directly onto the skin.
Položite konico pipete na kožo in jo nekajkrat močno stisnite, da nanesete vsebino neposredno na kožo.
Salivation, vomiting and neurological signs (tremor) were observed occasionally when the product was administered at up to 10 times the recommended dose in adult cats and up to 5 times the recommended dose in kittens.
Pri nanosu desetkratnega terapevtskega odmerka odraslim mačkam ter petkratnega terpevtskega odmerka mačjim mladičem, se je pri mačjih mladičih občasno pojavilo slinjenje, bruhanje ter nevrološki znaki npr. drget.
These symptoms were thought to occur as a result of the cat licking the application site.
Klinična znamenja so se pokazala le, če je žival zdravilo polizala.
The symptoms were completely reversible.
Ta znamenja so postopoma izginila.
Pharmacotherapeutic group: therapeutic antiparasitic agent; ATCvet code:
Farmakoterapevtska skupina: terapevtski antiparazitik, oznaka ATCvet:
In this product, emodepside is responsible for the efficacy against Toxocara cati, Toxascaris leonina, and Ancylostoma tubaeforme.
Emodepsid v pripravku deluje na Toxocara cati, Toxascaris leonina in Ancylostoma tubaeforme.
It acts at the neuromuscular junction by stimulating presynaptic receptors belonging to the secretin receptor family which results in paralysis and death of the parasites.
Deluje na živčno- mišičnem stiku tako, da draži presinaptične receptorje, ki spadajo v družino sekretinskih receptorjev, kar povzroči paralizo in pogin zajedavca.
This results in severe damage to the parasite integument, contraction and paralysis, disruption of metabolism and finally leads to the death of the parasite.
Posledica tega so poškodbe zajedavčeve povrhnjice, spazem in paraliza, prekinitev presnove in v zadnji fazi pogin zajedavca.
After topical application of this product to cats at the minimum therapeutic dose of 0.14 ml/ kg bodyweight, mean maximum serum concentrations of 32.2 ± 23.9 µg emodepside/ l and 61.3 ± 44.1 µg praziquantel/ l were observed.
Po nanosu najmanjšega terapevtskega odmerka pripravka na kožo mačke, ki znaša 0, 14 ml/ kg telesne mase, je bila najvišja plazemska koncentracija okoli 32, 2 ± 23, 9 µg emodepsida/ 1 in 61, 3 ± 44, 1 µg prazikvantela/ 1.
Maximum concentrations were reached for emodepside 3.2 ± 2.7 days after application and 18.7 ± 47 hours for praziquantel.
Najvišjo koncentracijo emodepsida v plazmi dosežemo 3, 2 ± 2, 7 dni po nanosu, najvišjo koncentracijo prazikvantela pa v 18, 7 ± 47, 0 urah po nanosu.
Both active substances are then slowly eliminated from the serum with a half-life of 9.2 ± 3.9 days for emodepside and 4.1 ± 1.5 days for praziquantel.
Razpolovna doba emodepsida je okoli 9, 2 ± 3, 9 dni, prazikvantela pa okoli 4, 1 ± 1, 5 dni.
Faecal excretion predominates with unchanged emodepside and hydroxylated derivatives as the major excretion products.
S fecesom se izločata hidroksilirani derivati in nespremenjen emodepsid.
Studies in many different species show that praziquantel is rapidly metabolised in the liver.
Raziskave na večjem številu različnih živalskih vrst so pokazale, da se prazikvantel hitro presnovi v jetrih.
Renal elimination predominates.
Glavni metaboliti so monohidroksi- cikloheksilni derivati, ki se izločajo v glavnem skozi ledvice.
5.3 Environmental properties
5. 3 Okoljski podatki
See section 6.6.
Glej poglavje 6. 6.
Pack sizes
Pakiranje:
0.35 ml, 0.70 ml and 1.12 ml per pipette
Pipete z 0, 35 ml, 0, 70 ml in 1, 12 ml raztopine za kožni nanos.
Blister packs containing 2, 4, 12, 20, or 40 unit dose pipettes; 0.70 ml pipette only: additional blister pack containing 80 pipettes
Samo pri 0, 70 ml pipeti: dodaten blister z 80 pipetami.
Container
Vsebnik:
White polypropylene pipettes with caps in aluminium blisters
Bela polipropilenska pipeta z navojno zaporko v aluminijastem pretisnem omotu.
Not all pack sizes may be marketed.
v prometu vsa navedena pakiranja.
Profender should not be allowed to enter surface water as emodepside has shown harmful effects on aquatic organisms.
Profender ne sme priti v vodotoke, ker je emodepsid nevaren za vodne organizme.
6 [Multi-dose bottle]
6 [Steklenica z večjim številom odmerkov]
Profender spot-on solution for cats
Profender, kožni nanos, raztopina za mačke
Tapeworms (Cestodes) Dipylidium caninum (adult) Taenia taeniaeformis (adult) Echinococcus multilocularis (adult)
Trakulje (Cestodi) Dipylidium caninum (zrele oblike) Taenia taeniaeformis (zrele oblike) Echinococcus multilocularis (zrele oblike)
7 Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.
Zajedavci lahko razvijejo odpornost proti antiparazitiku, ki ga pogosto uporabljamo.
4.5 Special precautions for use
7 4. 5 Posebni previdnostni ukrepi
This is thought to occur as a result of the cat licking the application site immediately after treatment.
Če mačka takoj po nanosu poliže mesto nanosa, se lahko zelo redko pojavi slinjenje in bruhanje.
Co-treatment with other drugs that are P-glycoprotein substrates/ inhibitors (for example, ivermectin and other antiparasitic macrocyclic lactones,
Sočasno zdravljenje z zdravili, ki so substrati/ inhibitorji P - glikoproteinov (npr. ivermektin in drugi protiparazitarni makrociklični laktoni, eritromicin, prednizolon in ciklosporin) lahko povzroči farmakokinetične interakcije.
4.9 Amounts to be administered and administration route
8 4. 9 Odmerjanje in pot uporabe
Body Weight Volume
Teža mačke
of Cat (kg) ≥ 0.5 - 2.5 > 2.5 - 5 > 5 - 8
≥0, 5 – 2, 5
(ml) 0.35 0.70 1.12
1, 12
(mg) 7.5 15 24
3 – 4, 8
(mg/ kg bw) (mg) 3 - 15 30 3-6 60 3 - 4.8 96
96
(mg/ kg bw) 12 - 60 12 - 24 12 - 19.2
12 – 19, 2
Take a standard disposable 1 ml syringe with luer nozzle and connect it to the adapter.
Vzemite običajno 1 ml brizgo z luerjevim nastavkom in jo povežite z nastavkom.
9 5.1 Pharmacodynamic properties
5. 1 Farmakodinamične lastnosti
Praziquantel is rapidly adsorbed via the surface of the parasites and acts primarily by changing the Ca++ permeability of the parasite membranes.
9 Prazikvantel hitro prehaja skozi celotno zajedavčevo telesno površino in vpliva predvsem na prepustnost zajedavčeve membrane za Ca2+ ione.
3 months
3 leta Rok uporabnosti zdravila po prvem odpiranju vsebnika je 3 mesece.
10 6.5 Nature and composition of immediate packaging
6. 5 Vrsta ovojnine in vsebina
Pack size:
Vsebnik:
Amber coloured glass bottle with teflon-coated stopper and micro-spike adapter with luer-port
14 ml Steklenica rumenkastorjave barve z zamaškom, obloženim s teflonom in koničastim nastavkom z luerjevim navojem.
Profender 15 mg/ 3 mg modified-release Tablets for Small Dogs Profender 50 mg/ 10 mg modified-release Tablets for Medium Dogs Profender 150 mg/ 30 mg modified-release Tablets for Large Dogs
Profender 15 mg/ 3 mg tablete s prirejenim sproščanjem za majhne pse Profender 50 mg/ 10 mg tablete s prirejenim sproščanjem za srednje velike pse Profender 150 mg/ 30 mg tablete s prirejenim sproščanjem za velike pse
Each tablet of Profender contains:
Vsaka tableta Profender- ja vsebuje:
Emodepside
emodepsid
Praziquantel
prazikvantel
The tablets can be divided into equal halves.
Rjave barve, v obliki kosti z obojestransko vtisnjeno oznako Tablete lahko razpolovimo.
For dogs suffering from, or at risk from, mixed parasitic infections caused by roundworms and tapeworms of the following species:
Za pse, ki imajo ali so izpostavljeni mešanim infekcijam z glistami in trakuljami:
Toxocara canis (mature adult, immature adult, L4 and L3) Toxascaris leonina (mature adult, immature adult and L4) Ancylostoma caninum (mature adult and immature adult) Uncinaria stenocephala (mature adult and immature adult) Trichuris vulpis (mature adult, immature adult)
Gliste (Nematoda) Toxocara canis (zrele, nezrele oblike, ličinke L4, L3) Toxascaris leonina (zrele, nezrele oblike, ličinke L4) Ancylostoma caninum (zrele, nezrele oblike) Uncinaria stenocephala (zrele, nezrele oblike) Trichuris vulpis (zrele, nezrele oblike)
Dipylidium caninum Taenia spp.
Trakulje (Cestoda) Dipylidium caninum Taenia spp.
Echinococcus multilocularis (mature adult and immature) Echinococcus granulosus (mature adult and immature)
Echinococcus multilocularis (zrele, nezrele oblike) Echinococcus granulosus (zrele, nezrele oblike)
12 4.3 Contraindications
12 4. 3 Kontraindikacije
For example overnight fasting is recommended if the dog is to be treated in the morning.
Priporočamo postenje psa preko noči, če mu boste dali tableto zjutraj.
Food may be given 4 hours or more after treatment.
Psu damo hrano 4 ali več ur po dajanju tablete.
Therefore, the veterinary medicinal product should only be used in such animals according to a benefit/ risk assessment by the responsible veterinarian.
Pri teh psih zdravilo uporabite samo v primeru, ko je odgovorni veterinar ocenil razmerje korist/ tveganje.
4.7 Use during pregnancy or lactation
4. 7 Uporaba v obdobju brejosti, laktacije ali nesnosti
The safety of the veterinary medicinal product has not been investigated in pregnant and lactating dogs.
Varnost zdravila v obdobju brejosti in laktacije ni bila raziskana.
Use in these dogs is therefore not recommended.
Ne priporočamo uporabe zdravila pri teh živalih.
Co-treatment with other drugs that are P-glycoprotein substrates/ inhibitors (for example, ivermectin and other antiparasitic macrocyclic lactones, erythromycin, prednisolone and cyclosporine) could give rise to pharmacokinetic drug interactions.
Sočasno zdravljenje s pripravki, ki so substrati/ inhibitorji P - glikoproteinov (npr. ivermektin in drugi protiparazitarni makrociklični laktoni, eritromicin, prednizolon in ciklosporin), lahko povzroči farmakokinetične interakcije.
13 4.9 Amounts to be administered and administration route
4. 9 Odmerjanje in pot uporabe
Profender is to be administered at a minimum dose of 1 mg/ kg body weight emodepside and 5 mg/ kg body weight praziquantel, according to the following dosage table.
Uporabimo tabelo za odmerjanje.
A single administration per treatment is effective.
13 Zadošča že enkratno dajanje.
Number of Profender tablets for Body Weight (kg)
Število tablet Profender Telesna masa (kg)
medium dogs
veliki psi
= 3 kg 1
= 3 kg
1 > 1.5 > 3 > 4.5 > 6 > 10 > 15 > 20 > 30 > 45
1 > 1, 5 > 3 > 4, 5 > 6
– – – – – – – – – –
– – – – –
1.5 3 4.5 6 10 15 20 30 45 60
1, 5 3 4, 5 6 10
Transient muscular tremors, incoordination and depression were occasionally observed when the veterinary product was administered at overdoses of up to 5 times the recommended dose.
Pri zaužitju 5- kratnega terapevtskega odmerka se je občasno pojavilo prehodno mišično drgetanje, nekoordiniranost gibov in potrtost.
In mdr1 mutant (-/-) Collies the margin of safety appears lower compared to the normal dog population, with mild transient tremor and/or ataxia occasionally observed after twice the recommended dose.
Pri kolijih, z mutacijo gena MDR1, se je je pri zaužitju 2- kratnega terapevtskega odmerka občasno pojavilo prehodno mišično drgetanje in nekoordiniranost gibov ker je varnost zdravila pri le- teh manjša v pimerjavi z običajno populacijo.
QP52AA51.
Farmakoterapevtska skupina: terapevtski antiparazitik; oznaka ATC vet QP52AA51.
In this product, emodepside is responsible for the efficacy against Toxocara canis, Toxascaris leonina, Ancylostoma caninum, Uncinaria stenocephala and Trichuris vulpis.
Emodepsid v pripravku deluje na Toxocara canis, Toxascaris leonina, Ancylostoma caninum, Uncinaria stenocephala in Trihuris vulpis.
Praziquantel is a pyrazinoisoquinoline derivative effective against tapeworms such as Dipylidium caninum, Taenia spp., Echinococcus multilocularis and Echinococcus granulosus.
Dipylidium caninum, Taenia spp., Echinococcus multilocularis in Echinococcus granulosus. Prazikvantel hitro
Praziquantel is rapidly adsorbed via the surface of the parasites and acts primarily by changing the calcium (Ca++) permeability of the parasite membranes.
14 prehaja skozi celotno zajedavčevo telesno površino in vpliva predvsem na prepustnost zajedavčeve membrane za kalcij (Ca++).
After treatment with a dose of 1.5 mg emodepside and 7.5 mg praziquantel per kg bodyweight, geometric mean maximum plasma concentrations of 47 µg emodepside/l and 593 µg praziquantel/l were observed.
Pri zdravljenju z odmerkom 1, 5 mg emodepsida in 7, 5 mg prazikvantela na kg telesne mase je znašal izračun povprečne vrednosti geometrične sredine plazemske koncentracije 47 µg emodepsida/ l in 593 µg prazkvantela/ l.
Maximum concentrations were reached 2 hours after treatment for both active substances.
Najvišjo koncentracijo obeh učinkovin dosežemo 2 uri po dajanju.
Both active substances were then eliminated from the plasma with a half-life of 1.4 to 1.7 hours.
Obe učinkovini se izločita iz seruma: razpolovni čas je od 1, 4 do 1, 7 ure.
Renal excretion of metabolites predominates.
Glavni presnovki so monohidroksi- cikloheksilni derivati prazikvantela, ki se izločajo v glavnem skozi ledvice.
Calcium hydrogen phosphate anhydrous Cellulose, microcrystalline Silica, colloidal anhydrous Croscarmellose sodium Magnesium stearate Povidone Artificial beef flavour
brezvodni kalcijev hidrogen fosfat mikrokristalinična celuloza silika, koloidni anhidrid premrežen natrijev karmelozat magnezijev sterat povidon umetni okus govedine
Store in the original package in order to protect from moisture.
Shranjujte v originalni ovojnini za zaščito pred vlago
15 6.5 Nature and composition of immediate packaging
6. 5 Vrsta ovojnine in vsebina
The following pack sizes are available:
Na razpolago se nasledenje velikosti pakiranja.
Profender 15 mg/3 mg tablets for small dogs
Profender 15 mg/ 3 mg tablete za majhne pse
2 tablets 4 tablets 10 tablets 24 tablets 50 tablets
- 2 tableti - 4 tablete - 10 tablet - 24 tablet - 50 tablet
(1 blister strip) (1 blister strip) (1 blister strip) (3 blister strips with 8 tablets each) (5 blister strips with 10 tablets each)
(1 pretisni omot) (1 pretisni omot) (1 pretisni omot) (3 pretisna omota po 8 tablet) (5 pretisnih omotov po 10 tablet)
Profender 50 mg/10 mg tablets for medium dogs
15 Profender 50 mg/ 10 mg tablete za srednje velike pse
2 tablets 4 tablets 6 tablets 24 tablets 102 tablets
- 2 tableti - 4 tablete - 6 tablet - 24 tablet - 102 tableti
(1 blister strip) (1 blister strip) (1 blister strip) (4 blister strips with 6 tablets each) (17 blister strips with 6 tablets each)
(1 pretisni omot) (1 pretisni omot) (1 pretisni omot) (4 pretisni omoti po 6 tablet) (17 pretisnih omotov po 6 tablet)
Profender 150 mg/30 mg tablets for large dogs
Profender 150 mg/ 30 mg tablete za velike pse
2 tablets 4 tablets 24 tablets 52 tablets
- 2 tableti - 4 tablete - 24 tablet - 52 tablet
(1 blister strip) (1 blister strip) (6 blister strips with 4 tablets each) (13 blister strips with 4 tablets each)
(1 pretisni omot) (1 pretisni omot) (6 pretisnih omotov po 4 tablete) (13 pretisnih omotov po 4 tablete)
Detailed information on this veterinary medicinal product is available on the website of the European Medicines Agency (EMEA) http://www.emea.europa.eu/.
Podrobne informacije o tem zdravilu za uporabo v veterinarski medicini so na voljo na spletni strani Evropske agencije za zdravila (European Medicines Agency, EMEA) http: // www. emea. europa. eu
324 D-24106 Kiel Germany
324 D- 24106 Kiel Nemčija
21 PARTICULARS TO APPEAR ON THE OUTER PACKAGE Profender spot-on solution for small cats Outer carton, pack size of 2 (or 4) pipettes
20 PODATKI NA ZUNANJI OVOJNINI Profender, kožni nanos, raztopina za majhne mačke Škatla z 2 (ali 4) pipetami
Profender spot-on solution for small cats
Profender, kožni nanos, raztopina za majhne mačke
Each 0.35 ml pipette contains:
Ena 0, 35 ml pipeta vsebuje:
7.5 mg emodepside, 30 mg praziquantel 5.4 mg/ml butylhydroxyanisole (E320; as antioxidant)
7, 5 mg emodepsida, 30, 0 mg prazikvantela 5, 4 mg/ ml butilhidroksianizola (E 320 kot antioksidant)
2 pipettes 4 pipettes
2 pipeti 4 pipete
For small cats ≥ 0.5 kg – 2.5 kg
Za majhne mačke ≥ 0, 5 – 2, 5 kg
Roundworms:
Gliste:
Bayer Animal Health GmbH, D-51368 Leverkusen, Germany
Bayer Animal Health GmbH, D- 51368 Leverkusen, Nemčija
EU/2/05/054/001 2 pipettes EU/2/05/054/002 4 pipettes
EU/ 2/ 05/ 054/ 001 2 pipeti EU/ 2/ 05/ 054/ 002 4 pipete
23 PARTICULARS TO APPEAR ON THE OUTER PACKAGE Profender spot-on solution for small cats Outer carton, pack size of 12 (20 or 40) pipettes
22 PODATKI NA ZUNANJI OVOJNINI Profender, kožni nanos, raztopina za majhne mačke Škatla z 12 (20 ali 40) pipetami
12 pipettes 20 pipettes 40 pipettes
12 pipet 20 pipet 40 pipet
For small cats ≥ 0.5 kg – 2.5 kg
Za male mačke ≥ 0, 5 – 2, 5 kg
EU/2/05/054/003 12 pipettes EU/2/05/054/004 20 pipettes EU/2/05/054/005 40 pipettes
EU/ 2/ 05/ 054/ 003 12 pipet EU/ 2/ 05/ 054/ 004 20 pipet EU/ 2/ 05/ 054/ 005 40 pipet
25 PARTICULARS TO APPEAR ON THE OUTER PACKAGE Profender spot-on solution for medium cats Outer carton, pack size of 2 (or 4) pipettes
24 PODATKI NA ZUNANJI OVOJNINI Profender, kožni nanos, raztopina za srednje velike mačke Škatla z 2 (ali 4) pipetami
Profender spot-on solution for medium cats
Profender, kožni nanos, raztopina za srednje velike mačke
Each 0.70 ml pipette contains:
Ena 0, 70 ml pipeta vsebuje:
15 mg emodepside, 60 mg praziquantel 5.4 mg/ml butylhydroxyanisole (E320; as antioxidant)
15, 0 mg emodepsida, 60, 0 mg prazikvantela 5, 4 mg/ ml butilhidroksianizola (E 320 kot antioksidant)
For medium cats > 2.5 kg – 5 kg
Za srednje velike mačke > 2, 5 – 5 kg