natgillin/translations-raw huggingface dataset:
Subcutaneous or intramuscular use
intramuskularna
Vial (PET)
(PET)
250 ml (1000 doses)
(1000
1 vial
0, 25 ml
0 days
uporaba
500 ml (2000 doses)
(2000
Per dose of 0.25 ml:
V odmerku po 0, 25 ml:
Active substance Inactivated whole cell suspension of Ornithobacterium rhinotracheale serotype A, strain B3263/ 91 1 x 107 cells *
Zdravilna učinkovina Inaktivirana suspenzija celic bakterije Ornithobacterium rhinotracheale, serotip A, sev B3263/ 91 1 x 107 celic *
* inducing a mean titre in the chickens of the potency test of at least 11.2 (log2).
* pri preizkusu učinkovitosti pri piščancih spodbudi nastanek srednjega titra, ki je najmanj 11, 2 (log2)
Adjuvant Light liquid paraffin:
Dodatek Redko tekoči parafin:
Excipients Traces of formaldehyde
Pomožne snovi Sledi formaldehida
For a list of excipients, see section 6.1
Za seznam pomožnih snovi glejte poglavje 6. 1.
2 4.5 Special precautions for use
4. 5 Posebni previdnostni ukrepi
Allow vaccine to reach room temperature (15-25°C) before using the vaccine.
Cepivo pred uporabo ogrejemo na sobno temperaturo (15- 25 °C).
Special precautions to be taken by the person administering the veterinary medicinal product to animals
2 Posebni previdnostni ukrepi, ki jih mora izvajati oseba, ki živalim daje zdravilo
Accidental injection/ self injection may result in severe pain and swelling, particularly if injected into a joint or finger, and in rare cases could result in the loss of the affected finger if prompt medical attention is not given.
Nenamerno injiciranje/ samoinjiciranje lahko povzroči hude bolečine in otekline, zlasti ob injiciranju v sklep ali prst, in lahko v izjemnih primerih, če ni zagotovljena takojšnja zdravniška oskrba, privede do izgube prizadetega prsta.
In laboratory studies, a local transient swelling was found at post mortem examination in up to 40% of the birds for at least 14 days after subcutaneous vaccination.
Pri laboratorijskih preskusih so pri posmrtni preiskavi zasledili prehodno lokalno oteklino pri 40% živali, ki je trajala najmanj 14 dni po subkutanem cepljenju.
Do not use in birds in lay (see section 4.3).
Izdelka ne smemo uporabljati v obdobju valjenja (glejte poglavje 4. 3).
The vaccination scheme consists of two injections with a dose of 0.25 ml, administered subcutaneously in the neck or intramuscularly in the breast.
Shema cepljenja je dve injekciji z odmerkom po 0, 25 ml subkutano na vratu ali intramuskularno v prsni predel.
Occasionally hardened minor local swellings (0.5 – 2.0 cm) were observed which disappeared within 21 days after vaccination.
Občasno so zasledili manjše otekline v obliki zatrdlin (0, 5 do 2, 0 cm), ki so minile v 21 dneh po cepljenju.
3 5.
3 6.
IMMUNOLOGICAL PROPERTIES
FARMACEVTSKI PODATKI
Do not mix with any other vaccine/ immunological product.
Izdelka ne smemo mešati z drugimi cepivi ali imunološkimi pripravki.
Use immediately after opening
15 mesecev Rok uporabnosti po prvem odpiranju vsebnika: uporabite takoj po odpiranju.
Store and transport at 2 - 8°C.
Shranjujte in prevažajte pri temperaturi 2- 8 ºC.
Intervet International Wim de Körverstraat 35 NL-5831 AN Boxmeer The Netherlands
Intervet International Wim de Körverstraat 35 NL- 5831 AN Boxmeer Nizozemska
The import, sale, supply and/ or use of the product is or may be prohibited in certain Member States on the whole or part of their territory pursuant to national animal health policy.
Uvoz, prodaja, oskrba in/ ali uporaba izdelka je ali je lahko prepovedana v nekaterih državah članicah na njihovem celotnem ozemlju ali delu ozemlja v skladu z nacionalnim programom zdravstvenega varstva živali.
Any person intending to import, sell, supply and/ or use the product must consult the relevant Member States Competent Authority on the current vaccination policies prior to the import, sale, supply and/ or use.
Vsakdo, ki namerava uvažati, prodajati, oskrbovati in/ ali uporabljati izdelek, se mora posvetovati s pristojnimi organi posamezne države članice o veljavnih programih cepljenja še pred uvozom, prodajo, oskrbo in/ ali uporabo.
MANUFACTURER OF THE BIOLOGICAL ACTIVE SUBSTANCE AND MANUFACTURING AUTHORISATION HOLDER RESPONSIBLE FOR BATCH RELEASE
IZDELOVALEC( IZDELOVALCI) BIOLOŠKE ZDRAVILNE UČINKOVINE (ZDRAVILNIH UČINKOVIN) IN IMETNIK( I) DOVOLJENJ( A) ZA IZDELAVO ZDRAVILA, ODGOVOREN( ODGOVORNI) ZA SPROŠČANJE SERIJE
• For the active principle of biological origin intended to produce immunity, Council Regulation (EEC) No 2377/ 90 does not apply.
2377/ 90 ne velja.
• The adjuvants and excipients listed are included in Annex II of Council Regulation (EEC) No 2377/ 90.
2377/ 90.
7 Pharmacologically active substance Mineral hydrocarbons, low to high viscosity including microcristalline waxes, approximately C10-C60; aliphatic, branched aliphatic and alicyclic compounds.
7 Farmakološko aktivna snov Mineralni ogljikovodiki, majhne do velike viskoznosti: mikrokristalni voski, približno C10– C60; alifatske, razvejane alifatske in aliciklične spojine
Animal Species All food producing species
Živalska vrsta vse živalske vrste, namenjene za prehrano ljudi
Other provisions Excludes aromatic and unsaturated compounds
Druge določbe Ne vsebuje aromatskih in nenasičenih spojin.
All food producing species All food producing species
vse živalske vrste, namenjene za prehrano ljudi
• Sorbitan oleate (E 494), Potassium
Natrijev klorid
dihydrogen phosphate (E 340), Disodium
vse živalske vrste, namenjene za prehrano ljudi
(E 339) and Potassium chloride (E 508) are approved as additives in foodstuffs for human consumption and therefore covered by Annex II of Council Regulation (EEC) No.
• Sorbitan oleat (E 494), kalijev dihidrogenfosfat (E 340), natrijev dihidrogenfosfat (E 339) in kalijev klorid (E 508) so odobreni prehrambeni dodatki, zato jih ureja Dodatek II Uredbe Sveta (EGS) št.
2377/ 90 for substances with an E- number1 (with the exception of preservatives listed in part C of Annex III to Council Directive 95/ 2/ EC2.).
2377/ 90 za substance s številom E1 (razen konzervansov, naštetih v delu C Dodatka III Uredbe Sveta 95/ 2/ ES2).
1 OJ No L272 of 25.10.1996, p.
L 272 z dne 25. 10. 1996, str.
2 2 OJ No L 61 of 18.3.1995, p.
L 61 z dne 18. 3. 1995, str.
Light liquid paraffin:
Inaktivirana suspenzija celic bakterije Ornithobacterium rhinotracheale, serotip A, sev B3263/ 91 1 x 107 celic * * pri preizkusu učinkovitosti pri piščancih spodbudi nastanek srednjega titra, ki je najmanj 11, 2 (log2) Redko tekoči parafin:
107.21 mg Traces of formaldehyde
107, 21 mg Sledi formaldehida
Subcutaneous injection in the neck or intramuscular injection in the breast of one dose of 0.25 ml.
En odmerek po 0, 25 ml subkutano na vratu ali intramuskularno v prsni predel
Oil adjuvanted vaccine Do not use for birds in lay.
Cepivo z oljnim adjuvansom Ne uporabljajte v obdobju valjenja.
Shelf life after first opening:
(mesec/ leto) ……. / ……… Rok uporabnosti po prvem odpiranju vsebnika:
Use immediately after opening
Uporabite takoj po pripravi.
Store and transport at 2 - 8°C.
Shranjujte in prevažajte pri temperaturi 2- 8 °C.
Lot: ……
Serija: ………
12 PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING
12 PODATKI NA STIČNI OVOJNINI
Inactivated whole cell suspension of O. rhinotracheale Light liquid paraffin
Inaktivirana suspenzija celic bakterije O. rhinotracheale Redko tekoči parafin
250 ml (1000 doses) 500 ml (2000 doses)
250 ml (1000 odmerkov) 500 ml (2000 odmerkov)
s. c. injection or i. m. injection of one dose of 0.25 ml.
En odmerek po 0, 25 ml s. c. ali i. m.
Once broached:
(Mesec/ leto) ……. / …… Po prvem odpiranju:
Use immediately
Uporabite takoj.
Batch: ……
Serija: ………
Inactivated whole cell suspension of Ornithobacterium rhinotracheale serotype A strain B3263/ 91 1 x 107 cells *
Inaktivirana suspenzija celic bakterije Ornithobacterium rhinotracheale, serotip A, sev B3263/ 91 1 x 107 celic *
* inducing a mean titre in the chickens of the potency test of at least 11.2 (log2).
* pri preizkusu potentnosti pri piščancih spodbudi nastanek srednjega titra, ki je najmanj 11, 2 (log2)
Light liquid paraffin:
Redko tekoči parafin:
Single dose of 0.25 ml.
Enkratni odmerek po 0, 25 ml.
Allow the vaccine to reach room temperature (15-25°C) before using the vaccine.
Cepivo pred uporabo ogrejte na sobno temperaturo (15- 25 °C).
17 To the physician:
17 Namenjeno zdravniku:
The product contains the inactivated whole cells of Ornithobacterium rhinotracheale serotype A, strain B3263/ 91 mixed with an oil adjuvant.
Izdelek vsebuje inaktivirane celice bakterije Ornithobacterium rhinotracheale, serotip A, sev B3263/ 91 v obliki mešanice z oljnim adjuvansom.
What is Nobilis IB 4-91?
Kaj je zdravilo Nobilis IB 4- 91?
Nobilis IB 4-91 is a lyophilised (freeze dried) vaccine pellet which is made into a solution for dosing.
Zdravilo Nobilis IB 4- 91 je peleta liofiliziranega cepiva za pripravo raztopine za odmerjanje.
Nobilis IB 4-91 contains the live attenuated (altered so that it does not cause the disease) avian Infectious Bronchitis Virus (IBV).
Zdravilo Nobilis IB 4- 91 vsebuje živ, oslabljen (spremenjen, tako da ne povzroča bolezni) virus infekcioznega bronhitisa (IBV) pri perutnini.
What is Nobilis IB 4-91 used for?
Za kaj se zdravilo Nobilis IB 4- 91 uporablja?
Nobilis IB 4-91 is used to immunise chickens to reduce the respiratory signs of Infectious Bronchitis caused by the variant strain IB 4-91, which causes infectious bronchitis in chickens.
Zdravilo Nobilis IB 4- 91 se uporablja za imunizacijo piščancev z namenom zmanjšanja respiratornih znakov infekcioznega bronhitisa, ki ga povzroča različica seva IB 4- 91, ki povzroča infekciozni bronhitis pri piščancih.
Nobilis IB 4-91 can be given to 1-day-old chicks and older chickens by coarse spray or by intranasal (breathed in through the nose) or ocular (absorbed by the eyes) administration.
Enodnevnim in starejšim piščancem se lahko zdravilo Nobilis IB 4- 91 daje z razpršilnikom z večjimi kapljicami, intranazalno (z vdihavanjem skozi nos) ali okularno (z absorpcijo skozi oči).
The vaccine can be given to 7-day and older chickens in their drinking water.
Sedemdnevnim in starejšim piščancem se lahko cepivo daje v vodo za pitje.
For long-lasting immunity, chickens should be revaccinated every 6 weeks.
Za podaljšano imunost je treba cepljenje piščancev ponavljati vsakih 6 tednov.
How does Nobilis IB 4-91 work?
Kako zdravilo Nobilis IB 4- 91 deluje?
Nobilis IB 4-91 contains the live IBV virus that has been attenuated (altered) so that it does not cause the disease.
Zdravilo Nobilis IB 4- 91 vsebuje živ virus IBV, ki je bil oslabljen (spremenjen), tako da ne povzroča bolezni.
When the chickens are exposed to this attenuated virus, this small exposure helps the chickens’ immune systems to recognise and attack the IBV virus.
Če so piščanci izpostavljeni temu oslabljenemu virusu, ta majhna izpostavitev pripomore, da imunski sistem piščancev prepozna in napade virus IBV.
When exposed to IBV later in life, the chickens will either not become infected or have a much less serious infection.
Če bodo piščanci virusu IBV izpostavljeni pozneje v življenju, se ne bodo okužili ali pa bodo imeli bistveno manj resno okužbo.
How has the effectiveness of Nobilis IB 4-91 been studied?
Kako je bila raziskana učinkovitost zdravila Nobilis IB 4- 91?
The Nobilis IB 4-91 vaccine has been studied in various vaccination schedules in a number of trials The vaccine was given by coarse spray to chicken of various ages.
Cepivo je bilo dajano z razpršilnikom z večjimi kapljicami piščancem različnih starosti.
The main measures of effectiveness included the development of antibodies to the IB 4-91 virus, the overall death rate of the chickens and the percentage of chicken rejected because of disease..
Glavna merila učinkovitosti so bila razvoj protiteles za virus IB 4- 91, celokupna smrtnost piščancev in odstotek piščancev, zavrnjenih zaradi bolezni.
Nobilis IB 4-91 vaccine has also been compared with controls, i. e. chickens that were not vaccinated.
Cepivo Nobilis IB 4- 91 so tudi primerjali s kontrolno skupino, tj. s piščanci, ki niso bili cepljeni.
(44-20) 74 18 84 00 Fax (44-20) 74 18 84 16 E-mail: mail@emea. europa. eu http: / /www. emea. europa. eu ©EMEA 2007 Reproduction and/ or distribution of this document is authorised for non commercial purposes only provided the EMEA is acknowledged What benefit has Nobilis IB 4-91 shown during the studies?
(44- 20) 74 18 84 00 Fax (44- 20) 74 18 84 16 E- mail: mail@ emea. europa. eu http: // www. emea. europa. eu ©EMEA 2007 Reproduction and/ or distribution of this document is authorised for non commercial purposes only provided the EMEA is acknowledged Kakšne koristi je zdravilo Nobilis IB 4- 91 izkazalo med raziskavami?
There was a clear immune response to Nobilis IB 4-91.
Na zdravilo Nobilis IB 4- 91 je bil jasen imunski odziv.
In one trial, after three weeks 100% of chickens had developed antibodies to the IB 4-91 virus compared with 17% for the controls.
V eni raziskavi je po treh tednih 100% piščancev razvilo protitelesa za virus IB 4- 91 v primerjavi s 17% v kontrolni skupini.
What are the side effects of Nobilis IB 4-91?
Kakšni so neželeni učinki zdravila Nobilis IB 4- 91?
Nobilis IB 4-91 can cause mild respiratory signs of disease which may last for a few days depending on the health and condition of the chickens.
Zdravilo Nobilis IB 4- 91 lahko povzroči blage oblike znakov obolenja dihalnih poti, ki lahko trajajo nekaj dni, odvisno od zdravja in splošnega stanja piščancev.
There are no precautions for the person, but it is recommended that they wash and disinfect hands and equipment after vaccinating to avoid spread of the virus.
Previdnostnih ukrepov ni, vendar je priporočljivo, da si po dajanju cepiva umije in razkuži roke in pripomočke, da prepreči širjenje virusa.
Why has Nobilis IB 4-91 been approved?
Zakaj je bilo zdravilo Nobilis IB 4- 91 odobreno?
The Committee for Medicinal Products for Veterinary Use (CVMP) agreed that the benefits of Nobilis IB 4-91 are greater than any risks to immunise chickens to reduce the respiratory signs of infectious bronchitis caused by the variant strain IB 4-91.
Odbor za zdravila za uporabo v veterinarski medicini (CVMP) je odločil, da so koristi zdravila Nobilis IB 4- 91 za imunizacijo piščancev z namenom zmanjšanja respiratornih znakov infekcioznega bronhitisa, ki ga povzroča različica seva IB 4- 91, večje od z njim povezanih tveganj.
They recommended that Nobilis IB 4-91 should be given a marketing authorisation.
Zato je priporočil, da se za zdravilo Nobilis IB 4- 91 odobri dovoljenje za promet.
Other information about Nobilis IB 4-91:
Druge informacije o zdravilu Nobilis IB 4- 91:
The European Commission granted a marketing authorisation valid throughout the European Union for Nobilis IB 4-91 to Intervet International B. V. on 9 June 1998.
Evropska Komisija je dovoljenje za promet z zdravilom Nobilis IB 4- 91, veljavno po vsej Evropski uniji, odobrila družbi Intervet International B. V. dne 9. junija 1998.
Information on the prescription status of this product may be found on the labelling.
Podatke o predpisovanju tega zdravila najdete na nalepki.
Withdrwal period
Karenca
Live attenuated avian Infectious Bronchitis Virus (IBV) variant strain 4-91: ≥ 3.6 log10 EID50 *
živi, oslabljeni
A lyophilised vaccine pellet for reconstitution
peleta
For intranasal/ ocular, spray or drinking water administration
za
vial of Type II hydrolytic glass
viala iz
1000 doses
1000
10 ml vial
viala po 10
Live attenuated avian Infectious Bronchitis Virus (IBV) variant strain 4-91: ≥ 3.6 log10 EID50 *
živi, oslabljeni variantni sev virusa kužnega bronhitisa perutnine (IBV) 4 - 91: ≥ 3, 6 log10 EID50 *
A lyophilised vaccine pellet for reconstitution
peleta liofiliziranega cepiva za rekonstitucijo
For intranasal/ ocular, spray or drinking water administration
za intranazalno/ okularno dajanje, razprševanje ali dajanje v vodi za pitje
vial of Type II hydrolytic glass
viala iz stekla 2. hidrolitične skupine
2500 doses
2500 odmerkov
10 ml vial
viala po 10 ml
5000 doses
5000 odmerkov
10000 doses
10000 odmerkov
1/ 3 EU Number
1/ 3 EU številka
10 x 2500 doses
10 x 2500 odmerkov
10 x 5000 doses
10000 odmerkov
10 x 10000 doses
10 x 10000 odmerkov
2/ 3 EU Number
2/ 3 EU številka
500 doses 10 ml vial
viala po 10
10 x 500 10 ml vial doses
10 x 500 odmerkov
* EID50 = 50% Embryo infective dose: the virus titre required to produce infection in 50% of the embryos inoculated.
* EID50 = 50- odstotni infektivni odmerek za zarodke: titer virusa, ki povzroči okužbo pri 50% inokuliranih zarodkov
Nobilis IB 4-91, lyophilisate for suspension
Nobilis IB 4- 91, liofilizat za suspenzijo
Each vial contains per dose:
Ena viala vsebuje v enem odmerku:
Live attenuated avian Infectious Bronchitis Virus (IBV) variant strain 4-91: ≥ 3.6 log10 EID50 *
Živi, oslabljeni variantni sev virusa kužnega bronhitisa perutnine (IBV) 4- 91: ≥ 3, 6 log10 EID50 *
* EID50 = 50% Embryo infective dose: the virus titre required to produce infection in 50% of the embryos inoculated.
* EID50 = 50- odstotni infektivni odmerek za zarodke: titer virusa, ki povzroči okužbo pri 50% inokuliranih zarodkov.
Lyophilisate for suspension.
Liofilizat za suspenzijo
Active immunisation of chickens to reduce the respiratory signs of Infectious Bronchitis caused by the variant strain IB 4-91.
Aktivna imunizacija piščancev za zmanjšanje respiratornih znakov kužnega bronhitisa, ki ga povzroča variantni sev IB 4- 91.
Future layers and breeders should not be vaccinated before 3 weeks of age.
4. 3 Kontraindikacije
Nobilis IB 4-91 given at day-old can adversely affect the efficacy of Turkey Rhinotracheitis (TRT) vaccine given within 7 days; therefore this vaccination scheme is contraindicated.
Nobilis IB 4- 91 lahko pri enodnevnih piščancih zmanjša učinkovitost cepiva proti rinotraheitisu puranov (TRT), danega v obdobju 7 dni, zato je takšna shema cepljenja kontraindicirana.
The vaccine virus may spread from vaccinated to non-vaccinated chickens and appropriate care should be taken to separate vaccinated from non-vaccinated.
Poskrbeti je treba, da so cepljeni piščancih ločeni od necepljenih.
Only healthy animals should be vaccinated.
Cepimo samo zdrave piščance.
Nobilis IB 4-91 is intended to protect chickens against respiratory signs of disease caused by IBV variant strain 4-91 only and should not be used as a replacement for other IBV vaccines.
Nobilis IB 4- 91 je namenjen samo za zaščito piščancev proti respiratornim znakom bolezni, ki jo povzroča variantni sev virusa kužnega bronhitisa perutnine 4- 91 in ga ne smemo uporabljati kot nadomestilo za druga cepiva, pripravljena iz virusov kužnega bronhitisa.
The product should only be used after it has been established that IBV variant strain 4-91 is epidemiologically
Izdelek smemo uporabiti, ko je dokazana
2/ 17 relevant in the area.
2/ 17 epidemiološka pomembnost variantnega seva virusa kužnega bronhitisa 4- 91 na območju, kjer ga bomo uporabili.
Vaccination with Nobilis IB 4-91 may induce mild respiratory signs of disease which may persist for a few days depending on the health and condition of the chickens.
Cepljenje z Nobilisom IB 4- 91 lahko povzroči blage respiratorne znake bolezni, ki lahko trajajo nekaj dni, odvisno od zdravstvenega in splošnega stanja piščancev.
Nobilis IB4-91 has been shown to be safe in layers and breeders during lay.
Pokazalo se je, da je uporaba Nobilisa IB4- 91 varna pri nesnicah in matični jati v obdobju nesnosti.
Nobilis IB 4-91 given at day-old can adversely affect the efficacy of Turkey Rhinotracheitis (TRT) vaccine given within 7 days.
Nobilis IB 4- 91 lahko pri starosti enega dne zmanjša učinkovitost cepiva proti rinotraheitisu puranov 7 dni po cepljenju.
At least 3.6 log10 EID50 (1 dose) per animal by either spray vaccination, drinking water or intranasal/ ocular administration.
Najmanj 3, 6 log10 EID50 (1 odmerek) za eno žival za cepljenje z razprševanjem, z dajanjem cepiva v vodi za pitje ali intranazalno ali okularno.
Guideline:
Navodilo:
Broiler:
Piščanci:
The vaccine can be administered to 1-day-old chicks and older chickens by coarse spray or by intranasal/ ocular administration.
Cepivo lahko pri enodnevnih in starejših piščancih razpršujemo z razpršilnikom z večjimi kapljicami ali ga dajemo intranazalno ali okularno.
Future layers and breeders:
Bodoče nesnice in matične jate:
The vaccine can be administered to future layers and breeders from three weeks of age onwards via intranasal/ ocular route, coarse spray or drinking water.
Po tretjem tednu starosti lahko dajemo cepivo bodočim nesnicam in matičnim jatam intranazalno ali okularno ter z razpršilnikom z večjimi kapljicami ali v vodi za pitje.
Spray method:
Razprševanje:
The vaccine should preferably be dissolved in distilled water or alternatively in cool, clean water.
Cepivo je najbolje razpustiti v destilirani vodi, lahko pa tudi v hladni, čisti vodi.
The appropriate number of vials should be opened under water.
Ustrezno število vial odpremo pod vodo.
This will vary according to the age of the chickens being vaccinated and the management system, but 250 to 400 ml of water per 1 000 doses is suggested.
Količina vode se lahko razlikuje glede na starost piščancev in sistem reje, vendar je priporočena količina 250 do 400 ml vode za 1000 odmerkov.
Drinking water:
Dajanje v vodi za pitje:
The vials should be opened under water.
Viale je treba odpreti pod vodo.
Use cool, clean water to dissolve the vaccine.
Cepivo razpustimo v hladni, čisti vodi.
For administration of the vaccine, as a general rule, dissolve 1 000 doses in one litre per age in days up to a maximum volume of 20 litres per 1 000 doses.
Po splošnem navodilu ga pripravimo tako, da razpustimo 1000 odmerkov v enem litru vode na starost v dnevih, do največjega volumna 20 litrov na 1000 odmerkov.
For heavy breeds, or in hot weather, the quantity of water may be increased up to 40 litres per 1 000 doses.
Pri težkih pasmah ali v vročem vremenu lahko količino vode povečamo do 40 litrov na 1000 odmerkov.
Feed should be available when vaccinating.
Pred cepljenjem piščancem ne dajemo vode, da ostanejo žejni.
Water should be withheld before vaccination to make the chickens thirsty.
Čas, ko jim odtegujemo vodo, je zelo odvisen od klimatskih razmer in naj bo čim krajši, vendar najmanj pol ure.
The length of time of water deprivation is strongly dependent on the climatological
Zadostno število posod za vodo, ki zagotovijo ustrezno velik prostor za pitje, je ključnega pomena.
Water withholding should be kept as short as possible with a minimum of half an hour.
3/ 17 Ko piščanci popijejo vso vodo s cepivom, odpremo sistem za napajanje.
Intranasal/ ocular administration:
Intranazalno in okularno dajanje:
Dissolve the vaccine in physiological saline solution or sterile distilled water (usually 30 ml per 1 000 doses, 75 ml per 2 500 doses) and administer by means of a standardized dropper.
Cepivo razpustimo v fiziološki raztopini soli ali sterilni destilirani vodi (običajno 30 ml za 1000 odmerkov, 75 ml za 2500 odmerkov) in ga dajemo s standardizirano kapalko.
Ocular/ intranasal administration or coarse spray, give the best responses and these should be the methods of choice, especially when vaccinating young chickens.
Po okularnem ali intranazalnem dajanju ter škropljenju z večjimi kapljicami je odzivnost najboljša, zato so ti načini izbirni načini dajanja, zlasti pri cepljenju mladih piščancev.
Vaccination programme:
Program cepljenja:
Active immunisation against avian Infectious Bronchitis virus variant strain IB 4-91 which causes infectious bronchitis in chickens.
Aktivna imunizacija proti variantnemu sevu kužnega bronhitisa perutnine IB 4- 91, ki povzroča kužni bronhitis pri piščancih
Sorbitol, gelatine, pancreatic digest of casein, disodium phosphate, water for injections
Sorbitol, želatina, pankreasni presnovek kazeina, dinatrijev fosfat, voda za injekcije
Do not mix with any other medicinal product..
Ne mešajte z nobenim drugim zdravilom.
In freeze-dried form:
Po rekonstituciji:
9 months at 2°C to 8°C.
9 mesecev pri 2 ºC do 8 ºC.
The vaccine should be used within 2 hours.
Cepivo je treba uporabiti v 2 urah.
Store at 2-8°C.
Shranjujte pri temperaturi 2– 8 °C.
4/ 17 6.5 Nature and composition of immediate packaging
6. 5 Vrsta ovojnine in vsebina