natgillin/translations-raw huggingface dataset:
54 Application at the base of the skull will minimise the opportunity for the cat to lick the product.
Koža ne sme biti poškodovana.
Do not store above 30°C.
Shranjujte nedosegljivo otrokom Ne shranjujte pri temperaturi nad 30 °C.
Do not use after the expiry date stated on the label and carton.
Zdravila ne smete uporabljati po datumu izteka roka uporabnosti, navedenega na zunanji in stični ovojnini.
Care should be taken that the contents of the pipette do not come into contact with the eyes or mouth of the recipient and/ or other animals.
Pazite, da zdravilo ne zaide v oči ali usta zdravljene in/ ali druge živali.
It is recommended that cats living in, or travelling to, areas endemic for heartworm are treated monthly with the product to protect them from heartworm disease.
Živali, ki živijo ali potujejo na področja, ki so okužena z Dirofilario immitis zdravimo enkrat mesečno.
Whilst the accuracy of diagnosis of feline heartworm infection is limited, it is recommended that attempts be made to check the heartworm status of any cat aged over 6 months, prior to beginning of prophylactic treatment, as use of the product on cats which have adult heartworm may cause serious adverse effects, including death.
Ker pri mačkah dirofilariozo težko diagnosticiramo, priporočamo, da pri mačkah, starejših od 6 mesecev, pred dajanjem zdravila, preverimo, če je inficirana z Dirofilario immitis, kajti dajanje zdravila mačkam, ki so okužene z odraslo obliko Dirofilarie immitis, lahko povzroči hud neželen škodljiv učinek zdravila, tudi smrt.
Treatment of animals weighing less than 1 kg should be based on a risk-benefit assessment.
Pri živalih, lažjih od 1 kg, je potrebno pred dajanjem oceniti razmerje korist/ tveganje.
However, frequent shampooing or immersion of the animal in water after treatment may reduce the efficacy of the product.
Vendar pa često šamponiranje ali stik živali z vodo neposredno po nanosu pripravka, zelo zmanjšata njegovo učinkovitost.
For persons administering Advocate to animals:
Za osebe, ki dajejo zdravilo Advocate živalim:
55 Wash hands thoroughly after use.
Po dajanju si temeljito umijte roke.
People with a known hypersensitivity to either benzyl alcohol, imidacloprid or moxidectin should administer the product with caution.
Osebe z znano preobčutljivostjo za benzilalkohol, imidakloprid ali moksidektin naj se izogibajo stiku z zdravilom.
In very rare cases the product may cause skin sensitisation or transient skin reactions (for example allergy, irritation or tingling).
V redkih primerih lahko zdravilo pri občutljivi koži povzroči prehodne kožne reakcije (npr. alergijo, vnetje ali srbenje).
If skin or eye symptoms persist, or the product is accidentally swallowed, seek medical attention and show the package insert to the physician.
Pri zaužiju zdravila ali, če zdraženje kože ali oči traja, poiščite zdravniško pomoč in pokažite navodilo za uporabo.
Imidacloprid is effective against larval flea stages and adult fleas.
DRUGE INFORMACIJE Imidakloprid je učinkovit pri uničevanju odraslih bolh in njihovih ličink.
Flea larvae in the pet’ s surroundings are killed after contact with a pet treated with the product.
Uničuje jih tudi v življenskem okolju zdravljene živali.
0.4 ml and 0.8 ml per pipette; blister packs containing 3, 4, 6, 21 or 42 unit dose pipettes.
pipeta s po 0, 4 ml in 0, 8 ml pretisni omoti s 3, 4, 6, 21 in 42 pipetami (enotami odmerka)
Not all pack sizes may be marketed.
vsa navedena pakiranja.
Eesti Magnum Veterinaaria AS Vae 16 EE-76401 Laagri Tel: +372 650 1920
54 Eesti Österreich Magnum Veterinaaria AS Vae 16 EE- 76401 Laagri Tel: +372 650 1920
Baix Llobregat, 3-5 E-08970 Sant Joan Despí (Barcelona) Tel: +34 93 4956500
Baix, Llobregat, 3- 5 E- 8970 Sant Joan Despí (Barcelona) Tel: +34 93 4956500
Latvija Magnum Veterinaaria AS Vae 16 EE-76401 Laagri Tel: +372 650 1920 Lietuva Magnum Veterinaaria AS Vae 16 EE-76401 Laagri Tel: +372 650 1920
55 Latvija Magnum Veterinaaria AS Vae 16 EE- 76401 Laagri Tel: +372 650 1920
58 PACKAGE LEAFLET Advocate spot-on solution for dogs
56 NAVODILO ZA UPORABO Advocate za pse
Imidacloprid
Imidakloprid Moksidektin
59 Do not use in puppies under 7 weeks of age.
Zdravila ne dajemo pasjim mladičem, mlajšim od 7 tednov.
Use only according to the risk-benefit assessment by the responsible veterinarian.
Zdravilo aplicirajte potem, ko odgovorni vetrinar oceni razmerje korist / tveganje dajanja.
For cats, the corresponding “ Advocate for cat” product, which contains 100 mg/ ml imidacloprid and 10 mg/ ml moxidectin, must be used.
Pri mačkah uporabljamo odgovarjajočo obliko zdravila Advocate za mačke, ki vsebuje 100 mg/ ml imidakloprida in 10 mg/ ml moksidektina.
If the animal licks the application site after treatment, transient neurological signs, such as ataxia, generalised tremors, ocular signs (dilated pupils, little pupillary reflex, nystagmus), abnormal respiration, salivation and vomiting, may occur infrequently.
Če pes poliže mesto aplikacije, se lahko pojavijo prehodni nevrološki znaki (nekontrolirani gibi, drhtenje), očesni znaki (razširjene zenice, slab pupilarni refleks, očesni drget), nenormalno dihanje, slinjenje in bruhanje.
Salivation may occasionally occur if the animal licks the application site immediately after treatment.
Ker je zdravilo grenko, se lako psi, ki po nanosu ližejo mesto aplikacije, slinijo.
The recommended minimum doses are 10 mg/ kg bodyweight imidacloprid and 2.5 mg/ kg bodyweight moxidectin, equivalent to 0.1 ml/ kg bodyweight Advocate for dogs.
Minimalni odmerek je 10 mg imidakloprida na kg telesne mase ter 2, 5 mg moksidektina na kg telesne mase kar ustreza 0, 1 ml zdravila Advocate za pse na kg telesne mase.
The treatment schedule should be based on the local epidemiological situation.
Shema zdravljenja poteka glede na lokalne epidemiološke razmere.
minimum of 10
Imidakloprid [mg/ kg t. m.] najmanj 10
minimum of 2.5
Moksidektin [mg/ kg t. m.] najmanj 2, 5
10 - 25
> 4 – 10 > 10 – 25
2.5 - 6.25
kg kg
Advocate for large dogs
Advocate za srednje velike pse Advocate za velike pse
2.5
1, 0 2, 5
10 - 25
10 – 25 10 – 25
2.5 – 6.25
2, 5 - 6, 25 2, 5 – 6, 25
> 25 – 40 kg
> 25 – 40 kg > 40 kg
Advocate for extra-large dogs
Advocate za zelo velike pse ustrezna velikost pipete
10 - 16
10 – 16
appropriate combination of pipettes
58 Zdravljenje in preprečevaje bolhavosti
Therefore before treatment with Advocate, the advice provided in the section ” SPECIAL WARNING(S )“ should be considered.
Zato moramo pred dajanjem zdravila Advocate upoštevati navodila v rubriki Posebna opozorila.
61 Treatment of Angiostrongylus vasorum
Zdravljenje infestacij z Angiostrongylus vasorum
Roundworm, hookworm and whipworm treatment
Preprečevanje infestacij zrazličnimi vrstami glist
For dogs up to 25 kg:
Pri psih do 25 kg telesne mase Pes naj stoji, razmaknite dlako med lopaticama, da bo vidna koža.
With the dog in a standing position, part the coat between the shoulder blades until the skin is visible.
Položite konico pipete na kožo in jo nekajkrat močno stisnite, da nanesete vsebino neposredno na kožo.
Wherever possible apply to undamaged skin.
Položite konico pipete na kožo in jo rahlo stisnite, da nanesete odgovarjajočo količino zdravila neposredno na kožo.
Keep out of the reach and sight of children.
Shranjujte nedosegljivo otrokom Ne shranjujte pri temperaturi nad 30 °C.
Do not use after the expiry date stated on the label and carton.
60 Zdravila ne smete uporabljati po datumu izteka roka uporabnosti, navedenega na zunanji in stični ovojnini.
Do not allow recently treated animals to groom each other.
Preprečite, da zdravljena žival ali druge živali z lizanjem mesta nanosa ne zaužijejo zdravila..
This product contains moxidectin (a macrocyclic lactone), therefore special care should be taken with Collies, Old English Sheepdogs and related breeds or crossbreeds, to correctly administer the product as described under the section “ ADVICE ON CORRECT ADMINISTRATION”; in particular, oral uptake by the recipient and/ or other animals in close contact should be prevented.
Pri tem pa upoštevamo nasvete o pravilni uporabi zdravila posebno tisti del, ki se nanaša zaužitje zdravila s strani tretirane in/ ali druge živali.
Although the product may be safely administered to dogs infected with adult heartworms, it has no therapeutic efficacy against adult Dirofilaria immitis.
Čeprav je zdravilo vareno za pse, ki imajo dirofilariozo pa terapevtsko ni učinkovit.
Dogs should not be allowed to swim in surface waters for 4 days after treatment.
Za osebe, ki dajejo pripravek Advocate živalim:
For persons administering Advocate to animals:
Preprečite stik zdravila s kožo, očmi ali usti.
63 Do not eat, drink or smoke during application.
Med nanosom ne jejte, pite in kadite.
If skin or eye symptoms persist, or the product is accidentally swallowed, seek medical attention and show the package insert to the physician.
Pri zaužitju zdravila in v primeru, da vzdraženje kože ali oči traja, poiščite zdravniško pomoč in pokažite navodilo za uporabo.
Imidacloprid is effective against larval flea stages and adult fleas.
61 Imidakloprid je učinkovit pri uničevanju odraslih bolh in njihovih ličink.
0.4 ml, 1.0 ml, 2.5 ml and 4.0 ml per pipette; blister packs containing 3, 4, 6, 21 or 42 unit dose pipettes.
pipete s po 1, 0 ml, 2, 5 ml in 4, 0 ml pretisni omoti s 3, 4, 6, 21 in 42 pipetami (enotami odmerka)
Ελλάδα ALAPIS ABEE GR– 19300, Ασπρόπυργος Αττικής, Τ .Θ.
62 Ελλάδα ALAPIS ABEE GR– 19300, Ασπρόπυργος Αττικής, Τ. Θ.
Baix Llobregat, 3-5 E-08970 Sant Joan Despí (Barcelona) Tel: +34 93 4956500
Baix, Llobregat, 3- 5 E- 08970 Sant Joan Despí (Barcelona) Tel: +34 93 4956500
France Bayer Santé Division Santé Animale 13, rue Jean Jaurès F– 92807 Puteaux cédex Tél: +33 1 49 06 58 19
France România Bayer Santé Division Santé Animale 13, rue Jean Jaurès F– 92807 Puteaux cédex Tél: +33 1 49 06 58 19
România S. C.
S. C.
Ireland Bayer Limited, Animal Health Division The Atrium Blackthorn Road IRL - Dublin 18
Ireland Bayer Limited, Animal Health Division The Atrium Blackthorn Road IRL Dublin 18 Tel: +353 1 2999313
Latvija Magnum Veterinaaria AS Vae 16 EE-76401 Laagri Tel: +372 650 1920 Lietuva Magnum Veterinaaria AS Vae 16 EE-76401 Laagri Tel: +372 650 1920
63 Latvija Magnum Veterinaaria AS Vae 16 EE- 76401 Laagri Tel: +372 650 1920
66
64
What is Aivlosin?
Kaj je zdravilo Aivlosin?
Aivlosin is available as a premix for medicated feeding stuff and as an oral powder for pigs, and as granules for use in drinking water for chickens.
Zdravilo Aivlosin je na voljo kot predmešanica za izdelavo medicinirane krme in kot peroralni prašek za prašiče ter kot granule za uporabo v pitni vodi za piščance.
The premix is mixed into pig feed by an authorised feed mill and the resulting “ medicated feeding stuff” is then distributed to the farmer to treat a large number of pigs.
Predmešanico v prašičjo krmo vmeša pooblaščeni izvajalec, ki se ukvarja z mletjem živalske krme; tako pridobljena „ medicinirana krma “ se nato razdeli kmetom za zdravljenje velikega števila prašičev.
The granules are added to the drinking water system, either directly or after dilution into a stock solution.
Granule se dodajo v sistem pitne vode, bodisi neposredno ali po razredčenju v osnovno raztopino.
What is Aivlosin used for?
Za kaj se zdravilo Aivlosin uporablja?
Swine Enzootic Pneumonia) or the intestinal tract (Swine Dysentery or Porcine Proliferative Enteropathy).
Pri prašičih se uporablja za zdravljenje ali preprečevanje številnih infekcijskih bolezni, ki jih povzročajo bakterije in prizadenejo pljuča (tj. enzootska pljučnica pri prašičih) ali črevesni trakt živali (prašičja griža ali prašičja proliferativna enteropatija).
In chickens, it is used to treat or prevent lung infections caused by a bacterium Mycoplasma gallisepticum.
Pri piščancih se uporablja za zdravljenje ali preprečevanje okužbe pljuč, ki jo povzroči bakterija Mycoplasma gallisepticum.
The active substance of Aivlosin is tylvalosin (previous name: acetylisovaleryltylosin), an antibiotic of the macrolide group.
Zdravilna učinkovina zdravila Aivlosin je tylvalosin (prejšnje ime: acetilizovaleriltilozin), antibiotik iz skupine makrolidov.
How has Aivlosin been studied?
Kako je bilo zdravilo Aivlosin raziskano?
The antimicrobial effectiveness of tylvalosin against bacteria causing diseases was investigated in microbiological laboratories.
Raziskave protimikrobne učinkovitosti tylvalosina proti bakterijam, ki povzročajo bolezni, so potekale v mikrobioloških laboratorijih.
The main clinical studies of the effectiveness of Aivlosin were carried out on farms in a number of countries in Europe as well as outside the EU.
Glavne klinične študije učinkovitosti zdravila Aivlosin so bile izvedene na kmetijah v več evropskih državah in zunaj EU.
The studies in pigs were carried out either in pigs already affected by the disease or in pigs who had been in contact with diseased animals on the same farm and, therefore, likely to develop the disease as well.
V študije so bili vključeni prašiči, ki so bodisi že zboleli ali pa so bili v stiku z bolnimi živalmi na isti kmetiji in je tako obstajala verjetnost, da se bo bolezen razvila tudi pri njih.
For the treatment of large numbers of pigs, Aivlosin was mixed into pig food by an authorised feed mill using the “ premix for medicated feeding stuff”.
Za zdravljenje velikega števila prašičev je zdravilo Aivlosin v krmo za prašiče vmešal pooblaščeni izvajalec, ki se ukvarja z mletjem živalske krme, pri čemer je uporabil „ predmešanico za medicinirano krmo “.
In order to achieve a good mixture in this large volume of food, special mixing equipment is needed and the mixing is done in several steps.
Da bi se sestavine te velike količine krme dobro premešale, je potrebna posebna oprema, mešanje pa poteka v več korakih.
For the treatment of individual pigs or a small number of animals, the animal owner mixed the medicine into the pig feed.
V primeru zdravljenja posameznih prašičev oziroma majhnega števila živali je zdravilo v prašičjo krmo vmešal lastnik živali.
In chicken, Aivlosin was used either to treat already diseased chicken or to help preventing an outbreak of the disease in very young chicks that hatched from eggs, which came from flocks where the disease is present.
Pri piščancih se je zdravilo Aivlosin uporabilo bodisi za zdravljenje že obolelega piščanca ali za preprečevanje izbruha bolezni pri zelo mladih piščetih, ki so se izvalili iz jajc, ki so prišle iz jat, pri katerih je bolezen prisotna.
The medicine was given with the drinking water at a dosage of 25 for three consecutive days.
Zdravilo se je dajalo tri dni zaporedoma s pitno vodo v odmerku 25 mg/ kg telesne mase.
In order to prevent an outbreak of the disease, chicks were treated in their first 3 days of life and treatment was repeated after about 2 weeks.
Da se prepreči izbruh bolezni, so bila piščeta zdravljena prve tri dni življenja, zdravljenje pa je bilo ponovljeno po približno dveh tednih.
During treatment, the birds did not receive any other water than the medicated drinking water.
Med zdravljenjem piščanci razen medicirane pitne vode niso prejemali nobene druge vode.
What benefit has Aivlosin shown during the studies?
Kakšne koristi je zdravilo Aivlosin izkazalo med študijami?
The studies showed that pigs treated with Aivlosin lost less weight during the infection and showed less severe signs of disease than untreated animals.
Študije so pokazale, da so prašiči, ki so jih zdravili z zdravilom Aivlosin, med okužbo izgubili manj mase in so poleg tega kazali manj resne znake obolenja kot živali, ki jih niso zdravili.
Chicken treated with Aivlosin showed less severe signs of disease than untreated animals.
Piščanci, zdravljeni z zdravilom Aivlosin, so kazali manj hude znake bolezni kot živali, ki niso bile zdravljene.
The effectiveness of Aivlosin was similar to that of other medicine of the same class already authorised for this disease in chicken.
Učinkovitost zdravila Aivlosin je bila podobna učinkovitosti drugih odobrenih zdravil iz iste skupine, ki se uporabljajo za zdravljenje te bolezni pri piščancih.
The treatment did not completely eliminate all bacteria in the respiratory system and some birds still showed the disease; however, the number of affected animals was significantly smaller than in an untreated group of birds.
Zdravljenje ni popolnoma odpravilo vseh bakterij v dihalnem sistemu, nekateri piščanci pa so še vedno kazali znake bolezni; vendar pa je bilo število okuženih živali občutno manjše od skupine piščancev, ki ni bila zdravljena.
Very ill pigs might not eat all the feed offered and therefore might get an insufficient amount of the medicine.
Hudo bolni prašiči mogoče ne bodo pojedli vse krme, kar pomeni, da mogoče ne bodo zaužili zadostne količine zdravila.
Therefore, treatment via feed with Aivlosin is not recommended for these animals.
Zato se pri teh živalih zdravljenje s krmo z zdravilom Aivlosin ne priporoča.
Since the composition of the pig feed might affect the effectiveness of Aivlosin, it should only be used in dry feed.
Ker lahko na učinkovitost zdravila Aivlosin vpliva tudi sestava krme za prašiče, smemo to zdravilo primešati izključno suhi krmi.
The oral powder cannot properly be mixed into pellets and should therefore not be used in pelleted pig feed.
Peroralnega praška ni mogoče ustrezno zmešati med pelete, zato ga ne smemo dodajati peletirani prašičji krmi.
The medicated drinking water should be replaced every 24 hours.
Medicirano pitno vodo je treba zamenjati vsakih 24 ur.
©EMEA 2008 2/ 3 What are the precautions for the person who gives the medicine or comes into contact with the animal?
Kakšne previdnostne ukrepe mora upoštevati oseba, ki daje zdravilo ali pride v stik z živaljo?
Aivlosin might cause skin reactions in some people.
Zdravilo Aivlosin lahko pri določenih ljudeh povzroči kožne reakcije.
People who had in the past skin reactions when handling Aivlosin or similar products, should avoid any contact with Aivlosin.
Priporočamo, da se ljudje, pri katerih so se v preteklosti med rokovanjem z zdravilom Aivlosin ali podobnimi proizvodi pojavile kožne reakcije, izogibajo kakršnemu koli stiku s tem zdravilom.
When mixing Aivlosin into feed or drinking water or handling the medicated feed or water, direct contact with eyes, skin and mouth should be avoided and protective equipment should be worn, e. g. overalls, gloves and face masks (respirator).
Treba je nositi ustrezno zaščitno opremo, npr. zaščitno obleko, rokavice in masko za obraz (dihalno masko).
However, if Aivlosin is accidentally consumed by a person, the advice of a doctor should be sought immediately.
Če kljub temu pride do nenamernega zaužitja zdravila, se nemudoma posvetujete z zdravnikom.
After the last administration of Aivlosin (in the feed or via drinking water), pigs or chickens should not be slaughtered for two days.
Po zaužitju zadnjega odmerka zdravila Aivlosin (s krmo ali pitno vodo) je treba pred zakolom prašičev ali piščancev počakati dva dni.
Aivlosin should not be used in hens that lay eggs for human consumption.
Zdravilo Aivlosin se ne sme uporabljati pri kokoših, ki nesejo jajca za prehrano ljudi.
It should, therefore, not be used in laying hens or in the two weeks before hens are likely to start laying eggs for human consumption.
Zato se ne sme uporabljati pri kokoših nesnicah ali dva tedna preden bodo kokoši verjetno začele nesti jajca za prehrano ljudi.
Why has Aivlosin been approved?
Zakaj je bilo zdravilo Aivlosin odobreno?
The Committee for Medicinal Products for Veterinary Use (CVMP) concluded that the benefits of Aivlosin are greater than any risks when Aivlosin is mixed into animal feed or drinking water and then used as described in the package leaflet.
Odbor za zdravila za uporabo v veterinarski medicini (CVMP) je zaključil, da so koristi zdravila Aivlosin, če se to vmeša v živalsko krmo in pitno vodo ter se uporabi v skladu z navodili za uporabo, večje od morebitnih tveganj.
The Committee recommended that Aivlosin should be given a marketing authorisation.
Odbor je zato priporočil, da se za zdravilo Aivlosin odobri dovoljenje za promet.
The European Commission granted a marketing authorisation valid throughout the European Union, for Aivlosin on 9 September 2004.
Evropska komisija je dovoljenje za promet z zdravilom Aivlosin, veljavno po vsej Evropski uniji, odobrila dne 9. septembra 2004.
This summary was last updated in May 2008.
Povzetek je bil nazadnje posodobljen 05- 2008.
©EMEA 2008 3/ 3
3/ 3
Pharmaceutical Form
Ciljna živalska vrsta
Target Route of species administration
Način uporabe Ovojnina zdravila
In-feed use
Dajanje v krmno mešanico
aluminium 42.5 mg/ g foil/ polyester laminated bag
Vreča iz aluminijeve 42, 5 mg/ g folije, laminirane s poliestrom
8.5 mg/ g Premix for medicated feeding stuff
8, 5 mg/ g Predmešanica za zdravilno krmno mešanico
Polyethylene 8.5 mg/ g lined paper bags
Papirnate vreče, 8, 5 mg/ g prevlečene s polietilenom
8.5 mg/ g Oral powder
8, 5 mg/ g Peroralni prašek
In drinking water use
Dajanje v vodo za pitje
Aluminium foil 625 mg/ g laminated sachet
Vrečka iz laminirane 625 mg/ g aluminijeve folije
2 days Not authorised for laying birds
2 dni Uporaba v obdobju nesnosti ni dovoljena.
Aivlosin 42.5 mg/ g Premix for medicated feeding stuff for pigs.
Aivlosin 42, 5 mg/ g predmešanica za izdelavo medicinirane krme za prašiče.
Tylvalosin (as Tylvalosin tartrate)
Zdravilna( e) učinkovina( e): tylvalosin
For a full list of excipients see section 6.1
Za celoten seznam pomožnih snovi, glejte poglavje 6. 1.
Premix for medicated feeding stuff A beige granular powder
Predmešanica za izdelavo medicinirane krme Bež zrnat prašek
4.2 Indications for use
4. 2 Indikacije za uporabo pri ciljnih živalskih vrstah
Treatment and prevention of Swine Enzootic Pneumonia caused by susceptible strains of Mycoplasma hyopneumoniae in pigs.
Zdravljenje in preprečevanje enzootske pljučnice pri prašičih, ki jo povzročajo občutljivi sevi Mycoplasma hyopneumoniae.
Treatment of Porcine Proliferative Enteropathy (ileitis) caused by Lawsonia intracellularis in herds where there is a diagnosis based on clinical history, post-mortem findings and clinical pathology results.
Zdravljenje prašičje proliferativne enteropatije (ileitis), ki jo povzroča Lawsonia intracellularis v čredah, kjer je bila diagnoza osnovana na klinični zgodovini, ugotovitvah post mortem in ugotovitvah klinične patologije.
Treatment of clinical outbreaks of Swine Dysentery, caused by Brachyspira hyodysenteriae in herds where the disease has been diagnosed and prevention of further clinical cases.
Zdravljenje kliničnih izbruhov dizenterije pri prašičih, ki jo povzroča Brachyspira Hydosenteriae, v čredah, kjer je bila diagnosticirana bolezen, in za preprečevanje nadaljnjih kliničnih primerov.
Generally, strains of B. hyodysenteriae have higher MIC values in cases of resistance against other macrolides, such as tylosin.
Sevi B. hyodysenteriae imajo v primerih rezistence na druge makrolide, kakršen je tilozin, v splošnem višje vrednosti MIK.
Cross-resistance between tylvalosin and other macrolides cannot be excluded.
Navzkrižna rezistenca med tylvalosinom in drugimi makrolidi ni izključena.
2 4.5 Special precautions for use
2 4. 5 Posebni previdnostni ukrepi
It is sound clinical practice to base treatment on susceptibility testing.
Zdravljenje naj temelji na testiranju občutljivosti.
Because Aivlosin has been shown to cause hypersensitivity reactions in laboratory animals, people with known hypersensitivity to tylvalosin tartrate should avoid any contact with the product.
Ker so pri laboratorijskih živalih opazili preobčutljivostne reakcije na Aivlosin, naj se ljudje z znano preobčutljivostjo na tylvalosin tartrat izogibajo stiku z zdravilom.
When mixing the veterinary medicinal product and handling the medicated feed, direct contact with eyes, skin and mucous membranes should be avoided.
Pri mešanju zdravila za uporabo v veterinarski medicini in pri rokovanju z medicinirano krmo se je treba izogibati direktnemu stiku z očmi, kožo in sluznicami.