natgillin/translations-raw huggingface dataset:
- If any of the side effects gets serious, or if you notice side effects not listed in this leaflet, please
- Če katerikoli neželeni učinek postane resen ali če opazite katerikoli neželeni učinek, ki ni
tell your doctor or pharmacist.
omenjen v tem navodilu, obvestite svojega zdravnika ali farmacevta.
What Corlentor is and what it is used for 2.
Kaj je zdravilo Corlentor in za kaj ga uporabljamo 2.
Before you take Corlentor 3.
Kaj morate vedeti, preden boste vzeli zdravilo Corlentor 3.
How to take Corlentor 4.
Kako jemati zdravilo Corlentor 4.
Possible side effects 5 How to store Corlentor 6.
Shranjevanje zdravila Corlentor 6.
WHAT CORLENTOR IS AND WHAT IT IS USED FOR
KAJ JE ZDRAVILO CORLENTOR IN ZA KAJ GA UPORABLJAMO
Corlentor is a heart medicine used to treat stable angina pectoris which causes chest pain, when beta- blockers (like atenolol, propranolol, metoprolol, etc, for high blood pressure, heart rhythm disorders, or angina pectoris) are not suitable.
Corlentor je zdravilo za srce, namenjeno za zdravljenje bolnikov s stabilno angino pektoris, boleznijo, ki povzroča bolečine v prsih, pri katerih zaviralci receptorjev beta (na primer atenolol, propranolol, metoprolol in drugi, proti zvišanemu krvnemu tlaku, motnjam srčnega ritma ali angini pektoris) niso ustrezni.
About stable angina pectoris (usually referred to as “ angina”):
O stabilni angini pektoris (običajno imenovani “ angina pektoris ”):
Angina is more likely to happen when the heart beats faster in situations such as exercise, emotion, exposure to the cold or after eating.
Angina pektoris se verjetneje pojavlja v položajih, kadar srce utripa hitreje, na primer med vadbo, ob razburjenju, izpostavljenosti mrazu ali po jedi.
How does Corlentor work?
Kako deluje Corlentor?
This lowers the heart’ s need for oxygen especially in the situations when an angina attack is more likely to happen.
Tako zmanjšuje potrebo srca po kisiku, zlasti v položajih, ko so anginozni napadi verjetnejši.
BEFORE YOU TAKE CORLENTOR
KAJ MORATE VEDETI, PREDEN BOSTE VZELI ZDRAVILO CORLENTOR
Do not take Corlentor:
Ne jemljite zdravila Corlentor:
- if you are allergic (hypersensitive) to ivabradine or any of the other ingredients of Corlentor;
- če ste alergični na (preobčutljivi za) ivabradin ali katerokoli sestavino zdravila Corlentor;
- if your resting heart rate before treatment is too slow (below 60 beats per minute);
- če je vaša srčna frekvenca med mirovanjem pred zdravljenjem prepočasna (manj kot 60 utripov
- if you are suffering from cardiogenic shock (a heart condition treated in hospital);
- če imate kardiogeni šok (bolezen srca, ki zahteva zdravljenje v bolnišnici);
- if you suffer from a heart rhythm disorder;
- če imate motnje srčnega ritma;
- if you are having a heart attack;
- če imate miokardni infarkt;
- if you suffer from very low blood pressure;
- če imate zelo nizek krvni tlak;
- if you suffer from unstable angina (a severe form in which chest pain occurs very frequently and
- če imate nestabilno angino pektoris (hudo obliko, pri kateri se bolečine v prsih pojavljajo zelo
with or without exertion);
pogosto, med naporom ali brez njega);
- if you suffer from severe heart failure (when your heart fails to work properly);
- če imate hudo srčno popuščanje (ko vaše srce ne deluje pravilno);
- if you have a pacemaker;
- če imate srčni spodbujevalnik;
- if you suffer from severe liver problems;
- če imate hude težave z jetri;
itraconazole), macrolide antibiotics (such as josamycin, clarithromycin, telithromycin or
- če že jemljete zdravila proti glivičnim okužbam (na primer ketokonazol, itrakonazol),
33 erythromycin given orally), medicines to treat HIV infections (such as nelfinavir, ritonavir) or nefazodone (medicine to treat depression) (see “ Taking other medicines”);
makrolidne antibiotike (na primer josamicin, klaritromicin, telitromicin ali eritromicin peroralno), zdravila proti okužbam z virusom HIV (na primer nelfinavir, ritonavir) ali nefazodon (zdravilo proti depresiji) (glejte “ Jemanje drugih zdravil ”);
- if you are pregnant;
- če ste noseči;
Take special care with Corlentor:
Bodite posebno pozorni pri jemanju zdravila Corlentor:
- if you suffer from a heart rhythm disorder,
- če imate motnje srčnega ritma;
- if you have symptoms such as tiredness or shortness of breath (this could mean that your heart is
- če opažate simptome, kot sta utrujenost ali zasoplost (to bi lahko pomenilo, da se vaše srce
slowing down too much),
preveč upočasnjuje);
- if you are already taking diltiazem, verapamil,
- če že jemljete diltiazem, verapamil;
- if you are taking QT prolonging medicines to treat either heart rhythm disorders or other
- če jemljete zdravila, ki podaljšujejo interval QT, za zdravljenje motenj srčnega ritma ali drugih
conditions (see the products listed in “ Taking other medicines”),
stanj (glejte zdravila, našteta v “ Jemanje drugih zdravil ”);
- if you suffer from sustained atrial fibrillation (a type of irregular heartbeat),
- če imate vztrajno atrijsko fibrilacijo (vrsto nerednega srčnega utripa);
- if you have had a recent stroke (cerebral attack),
- če ste nedavno imeli možgansko kap (možganski napad);
- if you suffer from mild to moderate low blood pressure,
- če imate blago do zmerno znižan krvni tlak;
- if you suffer from chronic heart failure (when your heart fails to work properly),
- če imate kronično srčno popuščanje (ko vaše srce ne deluje pravilno);
- if you suffer from chronic retinal disease,
- če imate kronično bolezen mrežnice;
- if you suffer from moderate liver problems,
- če imate zmerne težave z jetri;
- if you suffer from severe renal problems.
- če imate hude težave z ledvicami.
If any of the above applies to you, talk to your doctor before or while taking Corlentor.
Če karkoli od naštetega velja za vas, se pogovorite s svojim zdravnikom pred jemanjem zdravila Corlentor ali med njim.
Make sure to tell your doctor if you are taking any of the following medicines, as a dose adjustment of Corlentor or monitoring should be required:
Vedno povejte zdravniku, če jemljete katero od naslednjih zdravil, saj je lahko potrebno prilagajanje odmerka zdravila Corlentor ali spremljanje:
- diltiazem, verapamil (for high blood pressure or angina pectoris)
- diltiazem, verapamil (proti zvišanemu krvnemu tlaku ali angini pektoris)
- fluconazole (an antifungal agent)
- flukonazol (zdravilo proti glivicam)
- rifampicin (an antibiotic)
- rifampicin (antibiotik)
- barbiturates (for difficult sleeping or epilepsy)
- barbiturate (proti nespečnosti ali epilepsiji)
- phenytoin (for epilepsy)
- fenitoin (proti epilepsiji)
- Hypericum perforatum or St John’ s Wort (herbal treatment for depression)
- šentjanževko (Hypericum perforatum) (zdravilna rastlina proti depresiji)
- QT prolonging medicines to treat either heart rhythm disorders or other conditions such as:
- zdravila proti motnjam srčnega ritma ali drugim stanjem, ki podaljšujejo interval QT, kot so:
- quinidine, disopyramide, ibutilide, sotalol, amiodarone (to treat heart rhythm disorders)
- - -
- certain types of medicines to treat anxiety, schizophrenia or other psychoses (such as pimozide,
kinidin, dizopiramid, ibutilid, sotalol, amiodaron (proti motnjam srčnega ritma) bepridil (proti angini pektoris) določene vrste zdravil proti tesnobnosti, shizofreniji ali drugim psihozam (kot so pimozid, ziprazidon, sertindol)
ziprasidone, sertindole)
- - - -
- anti-malarial medicines (such as mefloquine or halofantrine)
zdravila proti malariji (na primer meflokin ali halofantrin) eritromicin v žilo (antibiotik) pentamidin (zdravilo proti parazitom) cisaprid (proti gastroezofagealnemu refluksu)
Taking Corlentor with food and drink:
Jemanje zdravila Corlentor skupaj s hrano in pijačo:
Limit your consumption of grapefruit juice during treatment with Corlentor.
Med zdravljenjem z zdravilom Corlentor omejite uživanje grenivkinega soka.
Do not take Corlentor if you are pregnant or planning a pregnancy (see “ Do not take Corlentor ”).
Ne jemljite zdravila Corlentor, če ste noseči ali načrtujete nosečnost (glejte “ Ne jemljite zdravila Corlentor ”).
Do not take Corlentor if you are breast-feeding (see “ Do not take Corlentor ”).
Ne jemljite zdravila Corlentor, če dojite (glejte “ Ne jemljite zdravila Corlentor ”).
34 Driving and using machines:
Vpliv na sposobnost upravljanja vozil in strojev:
Corlentor may cause temporary luminous visual phenomena (see “ 4.
34 Corlentor lahko povzroča začasne vidne pojave svetlikanja (glejte “ 4.
Possible side effects ”).
Možni neželeni učinki ”).
Important information about some of the ingredients of Corlentor:
Pomembne informacije o nekaterih sestavinah zdravila Corlentor:
Corlentor contains lactose.
Corlentor vsebuje laktozo.
HOW TO TAKE CORLENTOR
KAKO JEMATI ZDRAVILO CORLENTOR
Always take Corlentor exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
Če ste negotovi, se posvetujte z zdravnikom ali s farmacevtom.
The usual recommended starting dose is 1 tablet of Corlentor 5 mg twice daily increasing if necessary to 1 tablet of Corlentor 7.5 mg twice daily.
Običajen priporočljiv začetni odmerek je po 1 tableto zdravila Corlentor 5 mg dvakrat na dan, kar lahko povečate na 1 tableto zdravila Corlentor 7, 5 mg dvakrat na dan, če je potrebno.
The usual dose is one tablet in the morning and one tablet in the evening.
Običajno odmerjanje je eno tableto zjutraj in eno tableto zvečer.
In some cases (e. g. if you are elderly), your doctor may prescribe half the dose i. e., one half 5 mg tablet of Corlentor 5 mg (corresponding to 2.5 mg ivabradine) in the morning and one half 5 mg tablet in the evening.
Nekaterim bolnikom (na primer, če ste starejši) lahko zdravnik predpiše polovični odmerek, se pravi eno polovico 5- mg tablete (kar ustreza 2, 5 mg ivabradina) zjutraj in eno polovico 5- mg tablete zvečer.
Corlentor should be taken during meals.
Corlentor morate jemati med obroki.
If you think that the effect of Corlentor is too strong or too weak, talk to your doctor or pharmacist.
Če menite, da je učinek zdravila Corlentor premočan ali prešibak, se posvetujte z zdravnikom ali s farmacevtom.
Corlentor is not intended for use in children and adolescents younger than 18 years.
Corlentor ni namenjen za uporabo otrokom in mladostnikom, mlajšim od 18 let.
If you take more Corlentor than you should:
Če ste vzeli večji odmerek zdravila Corlentor, kot bi smeli:
A large dose of Corlentor could make you feel breathless or tired because your heart slows down too much.
Velik odmerek zdravila Corlentor bi lahko povzročil zasoplost ali utrujenost, ker preveč upočasni srce.
If you forget to take Corlentor:
Če ste pozabili vzeti zdravilo Corlentor:
If you stop taking Corlentor:
Če ste prenehali jemati zdravilo Corlentor:
As the treatment for angina is usually life-long, you should discuss with your doctor before stopping this medicinal product.
Ker je zdravljenje angine običajno doživljenjsko, se pred prenehanjem jemanja tega zdravila posvetujte z zdravnikom.
Like all medicines, Corlentor can cause side effects, although not everybody gets them.
Kot vsa zdravila ima lahko tudi zdravilo Corlentor neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
Very common side effects (more than 1 in 10 patients) reported with Corlentor are luminous visual phenomena (brief moments of increased brightness, most often caused by sudden changes in light intensity).
Zelo pogost neželeni učinek (več kot 1 bolnik na 10 bolnikov) ob zdravilu Corlentor so vidni pojavi svetlikanja (kratki trenutki povečane svetlosti, ki jih največkrat povzročajo nenadne spremembe jakosti svetlobe).
Other common side effects (more than 1 in 100 patients but less than 1 in 10 patients) include affecting the way the heart works (the symptoms are a slowing down of the heart rate), headache, dizziness, blurred vision and palpitations and cardiac extra beats which are uncommon (more than 1 in 1000 patients but less than 1 in 100 patients).
Drugi pogosti neželeni učinki (več kot 1 bolnik na 100 bolnikov, a manj kot 1 bolnik na 10 bolnikov) zajemajo tiste, ki vplivajo na način dela srca (simptom je upočasnitev srčne frekvence), glavobol, omotico, zamegljen vid in palpitacije ter dodatne srčne utripe, kar je redkeje (več kot 1 bolnik na 1. 000 bolnikov, a manj kot 1 bolnik na 100 bolnikov).
Also nausea, constipation, diarrhoea, vertigo, dyspnoea, muscle cramps and changes in laboratory parameters (blood tests) were reported uncommonly.
Prav tako so le občasno poročali o slabosti, zaprtju, driski, vrtoglavici, oteženem dihanju, mišičnih krčih in spremembah laboratorijskih parametrov (preiskave krvi).
35 5.
35 Če katerikoli neželeni učinek postane resen ali če opazite katerikoli neželeni učinek, ki ni omenjen v tem navodilu, obvestite svojega zdravnika ali farmacevta.
HOW TO STORE CORLENTOR
SHRANJEVANJE ZDRAVILA CORLENTOR
Do not use Corlentor after the expiry date which is stated on the carton and blister.
Zdravila Corlentor ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli in pretisnem omotu.
What Corlentor contains:
Kaj vsebuje zdravilo Corlentor:
Corlentor 5 mg: one film-coated tablet contains 5 mg ivabradine (equivalent to 5.390 mg ivabradine hydrochloride).
Corlentor 5 mg: ena filmsko obložena tableta vsebuje 5 mg ivabradina (kar ustreza 5, 390 mg ivabradinijevega klorida).
Corlentor 7.5 mg: one film-coated tablet contains 7.5 mg ivabradine (equivalent to 8.085 mg ivabradine hydrochloride).
Corlentor 7, 5 mg: ena filmsko obložena tableta vsebuje 7, 5 mg ivabradina (kar ustreza 8, 085 mg ivabradinijevega klorida).
- The other ingredients in the tablet core are: lactose monohydrate, magnesium stearate (E 470 B),
- Pomožne snovi so: laktoza monohidrat, magnezijev stearat (E 470 B), koruzni škrob,
maize starch, maltodextrin, colloidal anhydrous silica (E 551), and in the tablet coating: hypromellose (E 464), titanium dioxide (E 171), macrogol 6000, glycerol (E 422), magnesium stearate (E 470 B), yellow iron oxide (E 172), red iron oxide (E 172).
maltodekstrin, brezvoden koloidni silicijev dioksid (E 551) v jedru tablete in hipromeloza (E 464), titanov dioksid (E 171), makrogol 6000, glicerol (E 422), magnezijev stearat (E 470 B), rumeni železov oksid (E 172), rdeči železov oksid (E 172) v oblogi tablete.
What Corlentor looks like and contents of the pack:
Izgled zdravila Corlentor in vsebina pakiranja:
Corlentor 5 mg tablets are salmon-coloured, oblong film-coated tablets scored on both sides, engraved with “ 5 ” on one face and
Tablete zdravila Corlentor 5 mg so lososove barve, podolgovate in filmsko obložene, z zarezo na obeh straneh in vrezano oznako “ 5 ” na eni ter
on the other.
na drugi strani.
Corlentor 7.5 mg tablets are salmon-coloured, triangular, film-coated tablets engraved with “ 7.5 ” on one face and
Tablete zdravila Corlentor 7, 5 mg so lososove barve, trikotne in filmsko obložene, z zarezo na obeh straneh in vrezano oznako “ 7, 5 ” na eni ter
The tablets are available in calendar packs (blisters) of 14, 28, 56, 84, 98, 100 or 112 tablets.
Tablete so na voljo v koledarskih pakiranjih (pretisnih omotih), ki vsebujejo 14, 28, 56, 84, 98, 100 ali 112 tablet.
Not all pack sizes may be available.
Na voljo ni vseh navedenih pakiranj.
Les Laboratoires Servier 22 rue Garnier 92200 Neuilly sur Seine - France
Les Laboratoires Servier 22 rue Garnier 92200 Neuilly sur Seine – Francija
Les Laboratoires Servier Industrie 905 route de Saran 45520 Gidy – France
Les Laboratoires Servier Industrie 905 route de Saran 45520 Gidy – Francija
36 and
36 ter
Annopol 6B – 03-236 Warszawa – Poland
Annopol 6B – 03- 236 Varšava – Poljska
37 For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder.
37 Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
Lietuva UAB ” SERVIER PHARMA” Tel: +370 (5) 2 63 86 28
Navodilo je bilo odobreno:
Crixivan is a medicine containing the active substance indinavir.
Crixivan je zdravilo, ki vsebuje zdravilno učinkovino indinavir.
It is available as white capsules (100, 200, 333 and 400 mg).
Zdravilo je na voljo v obliki belih kapsul (100, 200, 333 in 400 mg).
Crixivan is an antiviral medicine.
Zdravilo Crixivan je protivirusno zdravilo.
It is used in combination with other antiviral medicines to treat adults, adolescents and children aged over four years who are infected with human immunodeficiency virus type 1 (HIV-1), a virus that causes acquired immune deficiency syndrome (AIDS).
Uporablja se v kombinaciji z drugimi protivirusnimi zdravili za zdravljenje odraslih, mladostnikov in otrok, starejših od štirih let, ki so okuženi z virusom humane imunske pomanjkljivosti tipa 1 (HIV– 1), virusom, ki povzroča sindrom pridobljene imunske pomanjkljivosti (AIDS).
In adolescents and children, the possible benefit of treatment with Crixivan should be weighed up against the increased risk of developing nephrolithiasis (kidney stones).
Pri mladostnikih in otrocih je morebitne koristi zdravljenja z zdravilom Crixivan treba pretehtati glede na povečano tveganje za nastanek ledvičnih kamnov.
The standard dose for adults is 800 mg every eight hours.
Običajni odmerek za odrasle je 800 mg vsakih osem ur.
For children, the dose depends on the body surface area (calculated using the child ’ s height and weight).
Pri otrocih je odmerek odvisen od površine telesa (izračunano glede na otrokovo višino in telesno maso).
The capsules should be swallowed whole without food but with water one hour before or two hours after a meal.
Kapsule je treba pogoltniti cele, in sicer brez hrane, vendar z vodo eno uro pred obrokom ali dve uri po njem.
In adults, Crixivan can also be taken at a dose of 400 mg twice a day if each dose is taken with 100 mg ritonavir (another antiviral medicine) with or without food, in combination with other antiviral medicines.
Odrasli lahko zdravilo Crixivan jemljejo tudi v odmerku 400 mg dvakrat na dan, če z vsakim odmerkom vzamejo tudi 100 mg ritonavirja (drugega protivirusnega zdravila) s hrano ali brez nje, v kombinaciji z drugimi protivirusnimi zdravili.
The use of Crixivan with ritonavir is based on limited evidence.
Uporaba zdravila Crixivan skupaj z ritonavirjem temelji na omejenih podatkih.
The dose of Crixivan will need to be adjusted in patients taking some other medicines or who have problems with their liver.
Odmerek zdravila Crixivan bo treba prilagoditi pri bolnikih, ki ga jemljejo sočasno z drugimi zdravili, ali tistih, ki imajo težave z jetri.
To avoid the risk of developing kidney stones, patients should drink plenty of liquids (at least 1.5 litres every day for adults).
Da bi se izognili tveganju za nastanek ledvičnih kamnov, morajo bolniki piti veliko tekočine (odrasli vsaj 1, 5 litra vsak dan).
When the enzyme is blocked, the virus does not reproduce normally, slowing down the spread of infection.
Ko je encim blokiran, se virus ne more več razmnoževati normalno, kar upočasni širjenje okužbe.
Crixivan
Zdravilo
Reproduction is authorised provided the source is acknowledged. does not cure HIV infection or AIDS, but it may delay the damage to the immune system and the development of infections and diseases associated with AIDS.
Reproduction is authorised provided the source is acknowledged Crixivan ne ozdravi okužbe s HIV ali AIDS- a, lahko pa upočasni slabšanje imunskega sistema ter razvoj okužb in bolezni, povezanih z AIDS- om.
Ritonavir is another protease inhibitor that is used as a ‘ booster’.
Ritonavir je drug zaviralec proteaze, ki se uporablja kot „ ojačevalec “.
The effectiveness of Crixivan taken without ritonavir has been studied in three studies involving 524 patients infected with HIV.
Učinkovitost zdravila Crixivan, uporabljenega brez ritonavirja, so preučevali v treh študijah, ki so vključevale 524 bolnikov, okuženih s HIV.
The first study compared the effects of Crixivan with those of zidovudine (another antiviral medicine) and the combination of both medicines.
V prvi študiji so učinke zdravila Crixivan primerjali z učinki zidovudina (drugega protivirusnega zdravila) in s kombinacijo obeh zdravil.
The other two studies compared Crixivan, taken with zidovudine and either didanosine or lamivudine (other antiviral medicines), with Crixivan taken alone, and with the combination of zidovudine and either didanosine or lamivudine.
V drugih dveh študijah so zdravilo Crixivan v kombinaciji z zidovudinom in didanozinom ali lamivudinom (druga protivirusna zdravila) primerjali z zdravilom Crixivan, uporabljenim samostojno, ter s kombinacijo zidovudina in didanozina ali lamivudina.
Crixivan, taken in combination with stavudine and lamivudine (other antiviral medicines), was also examined in 41 children aged between four and 15 years.
Pri 41 otrocih, starih od štiri do 15 let, so zdravilo Crixivan preučevali v kombinaciji s stavudinom in lamivudinom (drugima protivirusnima zdraviloma).
The main measure of effectiveness was the viral load (the level of HIV in the patient ’ s blood) after 24 weeks of treatment.
Glavno merilo učinkovitosti je bila virusna obremenitev (raven virusa HIV v krvi bolnikov) po 24 tednih zdravljenja.
The company also presented the results of four studies from the scientific literature that looked at the effects of taking Crixivan in combination with ritonavir.
Družba je predstavila tudi rezultate štirih študij iz znanstvene literature, ki so preučevale učinke jemanja zdravila Crixivan skupaj z ritonavirjem.
One study involved 20 patients who had already been taking Crixivan without ritonavir, and three involved a total of 123 patients who had not taken treatment for HIV infection before.
V eni študiji je sodelovalo 20 bolnikov, ki so že jemali zdravilo Crixivan brez ritonavirja, v preostale tri pa je bilo vključenih 123 bolnikov, ki predhodno zaradi okužbe s HIV še niso bili zdravljeni.
Crixivan, taken in combination with other antiviral medicines but without ritonavir, was more effective than comparator medicines in reducing viral loads.
Zdravilo Crixivan je bilo v kombinaciji z drugimi protivirusnimi zdravili, vendar brez ritonavirja, pri zmanjšanju virusne obremenitve učinkovitejše od primerjalnih zdravil.
In the first study, more patients taking Crixivan with zidovudine had a 99% reduction in viral load after 24 weeks, than those taking Crixivan alone.
V prvi študiji je do 99 – odstotnega zmanjšanja virusne obremenitve po 24 tednih prišlo pri večjem številu bolnikov, ki so zdravilo Crixivan jemali v kombinaciji z zidovudinom, kot pri tistih, ki so zdravilo Crixivan jemali samostojno.
In the second study, 53% of the patients taking Crixivan with two other antiviral medicines had reductions in viral load of at least 99%, compared with around 20% of those taking Crixivan alone or taking zidovudine and didanosine.
V drugi študiji je do najmanj 99– odstotnega zmanjšanja virusne obremenitve prišlo pri 53% bolnikov, ki so zdravilo Crixivan jemali v kombinaciji z dvema drugima protivirusnima zdraviloma, v primerjavi z okrog 20% bolnikov, ki so zdravilo Crixivan jemali samostojno ali v kombinaciji z zidovudinom ali didanozinom.
90% of those taking three medicines including Crixivan had viral loads below 500 copies/ ml, compared with 43% of those taking Crixivan alone and 0% of those taking two antiviral medicines.
V tretji študiji so bili doseženi podobni rezultati: virusna obremenitev pod 500 kopij/ ml je bila ugotovljena pri 90% bolnikov, ki so jemali tri zdravila, vključno z zdravilom Crixivan, in le pri 43% bolnikov, ki so jemali zdravilo Crixivan samostojno, ter pri 0% tistih, ki so jemali dve protivirusni zdravili.
Around half of the children tested had viral loads below 50 copies/ ml after 24 weeks of taking Crixivan with two other antiviral medicines.
Približno polovica testiranih otrok je po 24 tednih jemanja zdravila Crixivan z dvema drugima protivirusnima zdraviloma imela virusno obremenitev pod 500 kopij/ ml.
The studies of Crixivan taken with ritonavir showed that the combination produced similar blood levels of indinavir to Crixivan taken without ritonavir.
Študije jemanja zdravila Crixivan skupaj z ritonavirjem so pokazale, da so s to kombinacijo v krvi dosežene podobne ravni indinavirja, kot če se zdravilo Crixivan jemlje brez ritonavirja.