natgillin/translations-raw huggingface dataset:
GONAL-f is usually prescribed at a dose of 150 IU (0.25 ml) three times a week in combination with another medicine (hCG) for at least 4 months.
(0, 25 ml) trikrat na teden in v kombinaciji z drugim zdravilom (hCG) za najmanj 4 mesece.
Individual reconstituted vials should be for single patient use only.
Posamezne rekonstituirane viale sme uporabljati samo en bolnik.
The next injection should be done at the same time the next day.
Ker vsebuje viala dovolj zdravila za več dni zdravljenja, morate paziti, da odvzamete iz nje samo toliko zdravila kot vam je predpisal vaš zdravnik. Naslednjo injekcijo si morate dati ob istem času naslednji dan.
Your doctor has prescribed you a dose of GONAL-f in IU.
Vaš zdravnik vam je predpisal odmerek GONALA- f v i. e.
You should use one of the 15 administration syringes graduated in FSH units provided.
Uporabiti morate eno od 15 priloženih injekcijskih brizg za dajanje, graduiranih v FSH enotah.
Assemble everything you need:
Pripravite vse, kar potrebujete:
Find a clean area and lay out everything (two alcohol swabs, the 2 ml solvent pre-filled syringe, the vial containing GONAL-f and a syringe for administration).
Poiščite čisto površino, na katero razpostavite vse potrebne predmete (dve alkoholni blazinici, napolnjeno 2 ml injekcijsko brizgo z vehiklom, vialo z GONAL- f praškom in injekcijsko brizgo za dajanje).
See illustration.
Glejte sliko.
Prepare the injection solution:
Pripravite injekcijsko raztopino:
You should have a 2 ml pre-filled syringe containing clear liquid (the solvent) and one vial containing GONAL-f (the white powder).
Imeti morate 2 ml napolnjeno injekcijsko brizgo z bistro raztopino (vehikel) in eno vialo, ki vsebuje GONAL- f (beli prašek).
Remove the protective caps from the GONAL-f vial and from the solvent pre-filled syringe.
Odstranite zaščitno kapico
Pick up your pre-filled syringe of solvent and slowly inject all the solvent (2 ml) into the vial of GONAL-f powder.
Vzemite napolnjeno injekcijsko brizgo z vehiklom in počasi injicirajte ves vehikel (2 ml) v vialo z GONAL- f praškom.
Remove the syringe used for reconstitution from the vial and dispose of it.
Odstranite injekcijsko brizgo za rekonstitucijo iz viale in jo zavrzite.
This vial contains several doses of GONAL-f.
Viala vsebuje več odmerkov zdravila GONAL- f.
You will have to keep this vial several days and only draw the dose prescribed every day.
Vialo morate hraniti več dni in vsak dan odvzeti samo odmerek, ki vam ga je predpisal zdravnik.
Take the syringe for administration, fill it with air to the correct dose.
Vzemite injekcijsko brizgo za dajanje in jo napolnite z zrakom do pravilnega odmerka.
Shake gently the vial of GONAL-f with the solvent.
Rahlo stresajte vialo z GONALOM- f z vehiklom.
Insert the needle into the vial, turn the vial upside down, inject the air in the vial and draw the prescribed dose of GONAL-f into the syringe for administration.
Vstavite iglo v vialo, vialo obrnite navpično navzdol, injicirajte vanjo zrak in izvlecite predpisani odmerek Gonala- f v brizgo za dajanje.
Remove any air bubbles:
Odstranite morebitne zračne mehurčke: če vidite mehurčke zraka v injekcijski brizgi, jo primite
If you see air bubbles in the syringe, hold the syringe with the needle pointing upwards and gently flick the syringe until all the air collects at the top.
tako, da je igla usmerjena navzgor in nežno krcajte brizgo, da se ves zrak zbere na vrhu.
Inject the solution:
Injicirajte raztopino:
Once you have finished your injection, immediately discard the syringes used safely, preferably in a sharp container.
Ko ste zaključili z vbrizgavanjem, takoj varno odstranite uporabljene injekcijske brizge, po možnosti v posodo za ostre predmete.
For further injections with the reconstituted solution of GONAL-f, repeat steps 4. to 7.
Za nadaljnje injekcije rekonstituirane raztopine GONALA- f, ponovite korake od točke 4 do 7.
The reconstituted solution is for your use alone and should not be administered to other patients.
Rekonstituirana raztopina je samo za vašo uporabo in se je ne sme injicirati drugim bolnikom.
If you forget to take GONAL-f
222 Če ste pozabili vzeti zdravilo GONAL- f
Due to a local reactivity to benzyl alcohol, the same site of injection should not be used on consecutive days.
Zaradi lokalne odzivnosti na benzilalkohol, se ne sme uporabiti istega mesta injiciranja dva dni zaporedoma.
Rarely abnormal blood clottings (blood clots in blood vessels) have been seen to occur with similar medicines, so this could possibly occur with GONAL-f / hCG therapy or GONAL-f / lutropin alfa/ hCG therapy.
Redko so pri podobnih zdravilih opazili pojav nenormalnih krvnih strdkov (krvni strdki v žilah), torej bi se to lahko pojavilo tudi pri zdravljenju z GONALOM- f / hCG- jem ali GONALOM- f / lutropinom alfa / hCG- jem.
Store in the original package in order to protect from light.
223 Shranjujte v originalni ovojnini za zagotovitev zaščite pred svetlobo.
Do not use GONAL-f after the expiry date which is stated on the vial label or carton after EXP.
Zdravila GONAL- f ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na nalepki viale ali škatlici poleg oznake EXP.
Once the medicine is reconstituted (made up with the solvent), do not store above 25°C.
Rekonstituirano zdravilo (po pripravi z vehiklom) shranjujte pri temperaturi do 25°C.
Store in the original container and use within 28 days.
Shranjujte v originalnem vsebniku in uporabite v 28 dneh.
FURTHER INFORMATION
6 DODATNE INFORMACIJE
The active substance is follitropin alfa, 1050 IU/ 1.75 ml (77 micrograms/ 1.75 ml).
Zdravilna učinkovina je folitropin alfa, 1050 i. e / 1, 75 ml (77 mikrogramov / 1, 75 ml).
The solvent contains Water for Injections and benzyl alcohol 0.9%.
Vehikel vsebuje vodo za injekcije in 0, 9% benzilalkohola.
The solvent is a clear colourless solution.
Vehikel je bistra brezbarvna raztopina.
It is supplied in packs of 1 vial of powder with 1 pre-filled syringe of solvent and 15 disposable syringes for administration graduated in FSH units.
Na voljo je v škatlicah z 1 vialo s praškom, 1 napolnjeno injekcijsko brizgo z vehiklom in 15 injekcijskimi brizgami za dajanje zdravila za enkratno uporabo, ki so graduirane v FSH enotah.
One multidose vial of powder contains 1200 IU of follitropin alfa and one pre-filled syringe contains 2 ml of solvent.
Ena večodmerna viala s praškom vsebuje 1200 i. e. folitropina alfa in ena napolnjena injekcijska brizga vsebuje 2 ml vehikla.
223 For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder.
Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
België/ Belgique/ Belgien MERCK NV/ SA Brusselsesteenweg 288 B-3090 Overijse Tél/ Tel: +32-2-686 07 11
224 België/ Belgique/ Belgien MERCK NV/ SA Brusselsesteenweg 288 B- 3090 Overijse Tél/ Tel: +32- 2- 686 07 11
España Merck Farma y Química, S. L.
225 España Merck Farma y Química, S. L.
226 PACKAGE LEAFLET:
226 NAVODILO ZA UPORABO
GONAL-f 450 IU/ 0.75 ml (33 micrograms/ 0.75 ml) powder and solvent for solution for injection Follitropin alfa
Gonal- f 450 i. e. / 0, 75 ml (33 mikrogramov/ 0, 75 ml) prašek in vehikel za raztopino za injiciranje folitropin alfa
Before you use GONAL-f 3.
Kaj morate vedeti, preden boste uporabili zdravilo GONAL – f 3.
How to use GONAL-f 4.
Kako uporabljati zdravilo GONAL – f 4.
How to store GONAL-f 6.
Shranjevanje zdravila GONAL – f 6.
227 Do not use GONAL-f
227 Ne uporabljajte zdravila GONAL- f
• if you are allergic (hypersensitive) to follicle stimulating hormone or any of the other ingredients of GONAL-f. • if you have tumours of the hypothalamus and pituitary gland
• če alergični na (ste preobčutljivi za) folikle stimulirajoči hormon ali katerokoli sestavino zdravila GONAL- f, • če imate tumor hipotalamusa in hipofize
GONAL-f treatment in either indication seldom gives rise to significant OHSS unless the medicine used to induce final follicular maturation (containing human chorionic gonadotrophin - hCG) is administered.
Zdravljenje z GONALOM- f pri obeh indikacijah redko povzroči pomemben OHSS, razen če se uporabi zdravilo za spodbuditev končnega folikularnega zorenja (vsebuje človeški horionski gonadotropin – hCG).
228 Using other medicines
Uporaba drugih zdravil
GONAL-f 450 IU/ 0.75 ml (33 micrograms/ 0.75 ml) should not be mixed with other medicines in the same injection.
228 GONAL – f 450 i. e. / 0, 75 ml (33 mikrogramov/ 0, 75 ml) se ne sme mešati z drugimi zdravili v isti injekciji.
GONAL-f 450 IU/ 0.75 ml (33 micrograms/ 0.75 ml) preparation is not to be mixed with other GONAL-f containers within the same vial or syringe.
GONAL – f 450 i. e. / 0, 75 ml (33 mikrogramov/ 0, 75 ml) se ne sme mešati z drugimi vsebniki GONALA- f v isti viali ali injekcijski brizgi.
When an optimal response is obtained, a single injection of another medicine (hCG) is administered 24-48 hours after the last GONAL-f injection.
Ko je dosežen optimalni odziv, se v 24 – 48 urah po zadnji injekciji GONALA- f da ena sama injekcija drugega zdravila (hCG- ja).
A commonly used dose for superovulation involves the administration of 150-225 IU (0.25-0.38 ml) of GONAL-f daily, commencing on days 2 or 3 of the treatment cycle.
(0, 25 – 0, 38 ml) GONALA – f na dan, s pričetkom na 2. ali 3. dan ciklusa zdravljenja.
229 In other cases, down-regulation with a gonadotrophin-releasing hormone (GnRH) agonist is used.
V drugih primerih se uporabi negativna povratna regulacija z agonistom gonadotropin sproščajočega hormona (GnRH).
In these cases, GONAL-f is started approximately 2 weeks after the start of agonist treatment, both being continued until adequate follicular development is achieved.
V I primerih pričnemo z dajanjem GONALA- f približno 2 tedna po začetku zdravljenja z agonistom in nadaljujemo z dajanjem obeh zdravil, dokler ni dosežen zadovoljiv razvoj foliklov.
Women who are not ovulating, having no periods at all and have been diagnosed as FSH and LH deficient.
229 Ženske, ki nimajo ovulacije, sploh nimajo menstruacij in imajo ugotovljeno pomanjkanje FSH- ja in LH- ja.
When the desired response has been obtained, a single injection of hCG is given 24-48 hours after the last injections of GONAL-f and lutropin alfa.
Ko je dosežen želeni odziv, se v 24 – 48 urah po zadnji injekciji GONALA- f in lutropina alfa injicira ena sama injekcija hCG- ja.
You should use one of the 6 administration syringes graduated in FSH units provided.
Uporabiti morate eno od 6 priloženih injekcijskih brizg za dajanje, graduiranih v FSH enotah.
Find a clean area and lay out everything (two alcohol swabs, the 1 ml solvent pre-filled syringe, the vial containing GONAL-f and a syringe for administration).
Poiščite čisto površino, na katero razpostavite vse potrebne predmete (dve alkoholni blazinici, napolnjeno 1 ml injekcijsko brizgo z vehiklom, vialo z GONAL- f praškom in injekcijsko brizgo za dajanje).
230 See illustration.
Glejte sliko.
You should have a 1 ml pre-filled syringe containing clear liquid (the solvent) and one vial containing GONAL-f (the white powder).
Imeti morate 1 ml napolnjeno injekcijsko brizgo z bistro raztopino (vehikel) in eno vialo, ki vsebuje GONAL- f (beli prašek).
Remove the protective caps from the GONAL-f vial and from the solvent pre-filled syringe.
Odstranite zaščitno kapico z viale z GONAL- f praškom in z napolnjene injekcijske brizge z vehiklom.
Pick up your pre-filled syringe of solvent and slowly inject all the solvent (1 ml) into the vial of GONAL-f powder.
Vzemite napolnjeno injekcijsko brizgo z vehiklom in počasi injicirajte ves vehikel (1 ml) v vialo z GONAL- f praškom.
If you see air bubbles in the syringe, hold the syringe with the needle pointing upwards and gently flick the syringe until all the air collects at the top.
Odstranite morebitne zračne mehurčke: če vidite mehurčke zraka v injekcijski brizgi, jo primite tako, da je igla usmerjena navzgor in nežno krcajte brizgo, da se ves zrak zbere na vrhu.
If you forget to take GONAL-f
231 Če ste pozabili vzeti zdravilo GONAL- f
232 If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Če katerikoli neželeni učinek postane resen ali če opazite katerikoli neželeni učinek, ki ni omenjen v tem navodilu, obvestite svojega zdravnika ali farmacevta.
Prior to reconstitution, do not store above 25°C.
232 Pred rekonstitucijo shranjujte pri temperaturi do 25°C.
The active substance is follitropin alfa, 450 IU/ 0.75 ml (33 micrograms/ 0.75 ml).
Zdravilna učinkovina je folitropin alfa, 450 i. e / 0, 75 ml (33 mikrogramov / 0, 75 ml).
The solvent contains water for injections and benzyl alcohol 0.9%.
Vehikel vsebuje vodo za injekcije in 0, 9% benzilalkohola.
It is supplied in packs of 1 vial of powder with 1 pre-filled syringe of solvent and 6 disposable syringes for administration graduated in FSH units.
Na voljo je v škatlicah z 1 vialo s praškom, 1 napolnjeno injekcijsko brizgo z vehiklom in 6 injekcijskimi brizgami za dajanje zdravila za enkratno uporabo, ki so graduirane v FSH enotah.
One multidose vial of powder contains 600 IU of follitropin alfa and one pre-filled syringe contains 1 ml of solvent.
Ena večodmerna viala s praškom vsebuje 600 i. e. folitropina alfa in ena napolnjena injekcijska brizga vsebuje 1 ml vehikla.
233 Merck Serono S. p. A., Via delle Magnolie 15, I-70026 Modugno (Bari), Italy.
Merck Serono S. p. A., Via delle Magnolie 15, I- 70026 Modugno (Bari), Italija
België/ Belgique/ Belgien MERCK NV/ SA Brusselsesteenweg 288 B-3090 Overijse Tél/ Tel: +32-2-686 07 11
233 België/ Belgique/ Belgien MERCK NV/ SA Brusselsesteenweg 288 B- 3090 Overijse Tél/ Tel: +32- 2- 686 07 11
España Merck Farma y Química, S. L.
234 España Merck Farma y Química, S. L.
GONAL-f 300 IU/ 0.50 ml (22 micrograms/ 0.50 ml) powder and solvent for solution for injection Follitropin alfa
Gonal- f 300 i. e. / 0, 50 ml (22 mikrogramov/ 0, 50 ml) prašek in vehikel za raztopino za injiciranje folitropin alfa
237 Do not use GONAL-f
Ne uporabljajte zdravila GONAL- f
If you are a woman:
236 • če imate tumor hipotalamusa in hipofize
238 Using other medicines
Uporaba drugih zdravil
GONAL-f 300 IU/ 0.50 ml (22 micrograms/ 0.50 ml) should not be mixed with other medicines in the same injection.
GONAL - f 300 i. e. / 0, 50 ml (22 mikrogramov/ 0, 50 ml) se ne sme mešati z drugimi zdravili v isti injekciji.
GONAL-f 300 IU/ 0.50 ml (22 micrograms/ 0.50 ml) preparation is not to be mixed with other GONAL-f containers within the same vial or syringe.
GONAL - f 300 i. e. / 0, 50 ml (22 mikrogramov/ 0, 50 ml) se ne sme mešati z drugimi vsebniki
239 In other cases, down-regulation with a gonadotrophin-releasing hormone (GnRH) agonist is used.
V drugih primerih se uporabi negativna povratna regulacija z agonistom gonadotropin sproščajočega hormona (GnRH).
Women who are not ovulating, having no periods at all and have been diagnosed as FSH and LH deficient.
238 Ženske, ki nimajo ovulacije, sploh nimajo menstruacij in imajo ugotovljeno pomanjkanje FSH- ja in LH- ja.
You should use one of the 4 administration syringes graduated in FSH units provided.
Uporabiti morate eno od 4 priloženih injekcijskih brizg za dajanje, graduiranih v FSH enotah.
Find a clean area and lay out everything (two alcohol swabs, the pre-filled syringe, containing the solvent, the vial containing GONAL-f and a syringe for administration).
Poiščite čisto površino, na katero razpostavite vse potrebne predmete (dve alkoholni blazinici, napolnjeno 1 ml injekcijsko brizgo z vehiklom, vialo z GONAL- f praškom in injekcijsko brizgo za dajanje).
240 See illustration.
Glejte sliko.
You should have a pre-filled syringe containing clear liquid (the solvent) and one vial containing GONAL-f (the white powder).
Imeti morate napolnjeno injekcijsko brizgo z bistro raztopino (vehikel) in eno vialo, ki vsebuje GONAL- f (beli prašek).
Remove the protective caps from the GONAL-f vial and from the solvent pre- filled syringe.
Odstranite zaščitno kapico z viale z GONAL- f praškom in z napolnjene injekcijske brizge z vehiklom.
Pick up your pre-filled syringe of solvent and slowly inject all the solvent (0.75 ml) into the vial of GONAL-f powder.
Vzemite napolnjeno injekcijsko brizgo z vehiklom in počasi injicirajte ves vehikel (0, 75 ml) v vialo z GONAL- f praškom.
Your doctor or nurse will have already advised you where to inject (e. g. tummy, front of thigh).
Vaš zdravnik ali sestra sta vam že svetovala, kje dati injekcijo (n. pr. v trebuh, §sprednjo stran stegna).
Firmly pinch the skin together and insert the needle at a 45° to 90° angle using a dart- like motion.
Trdno stistnite ko žo skupaj in z gibom, podobnim metu sulice, zabodite iglo pod kotom 45° do 90°.
Following treatment with GONAL-f when human chorionic gonadotrophin is administered, a condition called ovarian hyperstimulation syndrome (see also section 2”) can occur.
Po zdravljenju z GONALOM - f, ki mu sledi dajanje človeškega horionskega gonadotropina, se lahko pojavi stanje, ki se imenuje sindrom hiperstimulacije jajčnikov (glejte tudi poglavje 2).
Some men undergoing treatment with GONAL-f may experience local reactions at the injection site (pain,
Pri nekaterih moških, ki se zdravijo z zdravilom GONAL - f, se lahko pojavi lokalna reakcija na mestu injiciranja (bolečina, rdečina, modrica, oteklina in / ali razdraženost) ali se razvije varikokela (razširitev ven nad in za testisi).
242 redness, bruising, swelling and/ or irritation) or may develop a varicocele (swelling of the veins above and behind the testicle).
Če katerikoli neželeni učinek postane resen ali če opazite katerikoli neželeni učinek, ki ni omenjen v
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
241 tem navodilu, obvestite svojega zdravnika ali farmacevta.
The active substance is follitropin alfa, 300 IU/ 0.50 ml (22 micrograms/ 0.50 ml).
Zdravilna učinkovina je folitropin alfa, 300 i. e / 0, 50 ml (22 mikrogramov / 0, 50 ml).
It is supplied in packs of 1 vial of powder with 1 pre-filled syringe of solvent and 4 disposable syringes for administration graduated in FSH units.
Na voljo je v škatlicah z 1 vialo s praškom, 1 napolnjeno injekcijsko brizgo z vehiklom in 4 injekcijskimi brizgami za dajanje zdravila za enkratno uporabo, ki so graduirane v FSH enotah.
One multidose vial of powder contains 450 IU of follitropin alfa and one pre-filled syringe contains 0.75 ml of solvent.
Ena večodmerna viala s praškom vsebuje 450 i. e. folitropina alfa in ena napolnjena injekcijska brizga vsebuje 0, 75 ml vehikla.
243 Manufacturer
242 Izdelovalec
España Merck Farma y Química, S. L.
243 España Merck Farma y Química, S. L.
INFORMATION FOR THE USER
244 NAVODILA ZA UPORABO
GONAL-f 300 IU/ 0.5 ml (22 micrograms/ 0.5 ml) solution for injection in a pre-filled pen Follitropin alfa
GONAL- f 300 i. e. / 0, 5 ml (22 mikrogramov/ 0, 5 ml) raztopina v napolnjenem injekcijskem peresniku folitropin alfa.
• GONAL-f can be used to cause ovulation in women who are not ovulating and who have not responded to treatment with clomiphene citrate.
• Pri ženskah, ki nimajo ovulacije in se ne odzivajo na zdravljenje s klomifen citratom, se lahko uporabi GONAL- f za sprožitev ovulacije.
• GONAL-f is used together with another hormone called lutropin alfa (recombinant human luteinising hormone) to cause ovulation in women who are not ovulating due to very low production of the fertility hormones (FSH and LH) by their pituitary gland.
• Pri ženskah, ki nimajo ovulacije zaradi zelo majhnega izločanja fertilnih hormonov (FSH in LH) iz hipofize, se za sprožitev ovulacije uporablja GONAL- f, skupaj z drugim hormonom, ki se imenuje lutropin alfa (rekombinantni humani luteinizirajoči hormon).
• GONAL-f is used in combination with another medicine, human chorionic gonadotrophin (hCG), to produce sperm in men who are infertile due to hormonal deficiency.
• GONAL- f se uporablja v kombinaciji z drugim zdravilom, človeškim horionskim gonadotropinom (hCG), za tvorbo sperme pri moških, ki so neplodni zaradi hormonske insuficience.
247 Do not use GONAL-f
Ne uporabljajte zdravila GONAL- f
• if you are allergic (hypersensitive) to follicle stimulating hormone or any of the other ingredients of GONAL-f • if you have tumours of the hypothalamus and pituitary gland
• če ste alergični na (preobčutljivi za) folikle stimulirajoči hormon ali za katerokoli sestavino zdravila GONAL- f • če imate tumorje hipotalamusa in hipofize
• if you have ovarian enlargement or cyst not due to polycystic ovarian disease • if you have gynaecological bleeding of unknown cause • if you have ovarian, uterine or breast cancer
245 Če ste ženska: • če imate povečanje jajčnika ali cista, ki ni posledica policistične ovarijske bolezni • če imate ginekološko krvavitev zaradi nepojasnjenega vzroka • če imate rak jajčnika, maternice ali dojke
• if you have irreversible testicular damage.
• Če imate nepopravljivo poškodbo testisov.
If you are a woman, this treatment increases your risk of developing ovarian hyperstimulation syndrome (OHSS) (see Section 4).
Če ste ženska, to zdravljenje povečuje tveganje za razvoj sindroma hiperstimulacije jajčnikov (OHSS) (glejte poglavje 4).
GONAL-f treatment seldom gives rise to significant OHSS unless the medicine used to induce final follicular maturation (containing human chorionic gonadotrophin - hCG) is administered.
Zdravljenje z GONALOM- f pri obeh indikacijah redko povzroči pomemben OHSS, razen če se uporabi zdravilo za spodbuditev končnega folikularnega zorenja (vsebuje človeški horionski gonadotropin - hCG).
248 Concomitant use of GONAL-f with other agents used to stimulate ovulation (e. g. hCG, clomiphene citrate) may potentiate the follicular response, whereas concurrent use of a GnRH agonist or antagonist to induce down regulation may increase the dosage of GONAL-f needed to elicit an adequate ovarian response.
Sočasna uporaba GONALA- f z drugimi sredstvi, ki se uporabljajo za stimulacijo ovulacije (npr. hCG, klomifen citrat) lahko potencira folikularani odziv, medtem ko hkratna uporaba agonista ali antagonista GnRH za sprožitev negativne povratne regulacije lahko poveča odmerek GONALA- f, ki je potreben za dosego ustreznega odziva jajčnikov.
Pregnancy and breast-feeding
246 Nosečnost in dojenje
A commonly used dose starts at 75-150 IU FSH every day (0.12-0.24 ml).
FSH vsak dan (0, 12 – 0, 24 ml).
This may be increased by 37.5-75 IU at 7 or preferably 14 day intervals if necessary to obtain an adequate, but not excessive, response.
Če je potrebno, se lahko za doseganje zadostnega, a ne pretiranega odziva, odmerek poveča za 37, 5 i. e. – 75 i. e. na 7 dni ali še bolje na 14 dni.
The maximal daily dose is usually lower than 225 IU FSH (0.36 ml).
FSH (0, 36 ml).
If an excessive response is obtained, treatment should be stopped and hCG withheld (see section 4).
Če pride do pretiranega odziva, je treba zdravljenje prekiniti in opustiti uporabo hCG (glejte poglavje 4).
Women undergoing ovarian stimulation for multiple follicular development prior to in vitro fertilisation or other assisted reproductive technologies.
Ženske v postopku stimulacije jajčnikov za doseganje razvoja več foliklov pred in vitro oploditvijo ali drugimi tehnikami asistirane reprodukcije:
A commonly used dose for superovulation involves the administration of 150-225 IU (0.24-0.36 ml) of GONAL-f daily, commencing on days 2 or 3 of the treatment cycle.
(0, 24 – 0, 36 ml) GONALA - f na dan, s pričetkom na 2. ali 3. dan ciklusa zdravljenja.
Treatment is continued until adequate follicular development has been achieved (as assessed by blood monitoring and/ or ultrasound examination), with the dose adjusted according to your response, to usually not higher than 450 IU (0.72 ml) daily.
(0, 72 ml) na dan.
Then a single injection of a medicine used to induce final follicular maturation and containing 250 micrograms r-hCG or 5000 IU up to 10 000 IU human chorionic gonadotrophin (hCG) is administered 24-48 hours after the last GONAL-f injection.
Nato se v 24- 48 urah po zadnji injekciji GONALA- f injicira ena sama injekcija zdravila za sprožitev končnega zorenja foliklov, ki vsebuje 250 mikrogramov r- hCG ali 5000 i. e. do 10 000 i. e. humanega horionskega gonadotropina (hCG- ja).