natgillin/translations-raw huggingface dataset:
Children should not take Aprovel Aprovel should not be given to children under 18 years of age.
Otroci ne smejo jemati zdravila Aprovel Otroci in mladostniki, mlajši od 18 let, zdravila Aprovel ne smejo jemati.
If you forget to take Aprovel If you accidentally miss a daily dose, just take the next dose as normal.
Če ste pozabili vzeti zdravilo Aprovel Če ste pozabili vzeti dnevni odmerek, vzemite le naslednji predvideni odmerek ob običajnem času.
Like all medicines, Aprovel can cause side effects, although not everybody gets them.
Kot vsa zdravila ima lahko tudi zdravilo Aprovel neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
As with similar medicines, rare cases of allergic skin reactions (rash, urticaria), as well as localised swelling of the face, lips and/ or tongue have been reported in patients taking irbesartan.
Kot pri drugih podobnih zdravilih so tudi pri uporabi irbesartana pri bolnikih poročali o redkih primerih alergijskih kožnih reakcij (izpuščaj, koprivnica) in lokaliziranih oteklinah obraza, ustnic in/ ali jezika.
Very common: at least 1 in 10 patients or more Common: at least 1 in 100 and less than 1 in 10 patients Uncommon: at least 1 in 1000 and less than 1 in 100 patients
V nadaljevanju so neželeni učinki navedeni po pogostnosti v skladu z naslednjim dogovorom: zelo pogosti: pri vsaj 1 od 10 bolnikov ali več pogosti: pri vsaj 1 od 100 in manj kot 1 od 10 bolnikov občasni: pri vsaj 1 od 1. 000 in manj kot 1 od 100 bolnikov
Common: dizziness, feeling sick/ vomiting, fatigue and blood tests may show raised levels of an enzyme that measures the muscle and heart function (creatine kinase enzyme).
Krvne preiskave lahko pokažejo zvišanje vrednosti encima, ki kaže na delovanje mišic in srca (encim kreatin- kinaza).
Uncommon: heart rate increased, flushing, cough, diarrhoea, indigestion/ heartburn, sexual dysfunction (problems with sexual performance), chest pain.
Občasni: hitro utripanje srca, rdečica, kašelj, driska, motnje prebave/ zgaga, motnje pri spolnih aktivnostih, bolečina v prsnem košu.
Some undesirable effects have been reported since marketing of Aprovel but the frequency for them to occur is not known.
Po prihodu zdravila Aprovel na tržišče so poročali še o nekaterih drugih neželenih učinkih, vendar pa njihova pogostnost ni znana.
These undesirable effects are: headache, taste disturbance, ringing in the ears, muscle cramps, pain in joints and muscles, abnormal liver function, increased blood potassium levels, impaired kidney function, and inflammation of small blood vessels mainly affecting the skin (a condition known as leukocytoclastic vasculitis).
Ti neželeni učinki so: glavobol, motnje okušanja, zvonjenje v ušesih, mišični krči, bolečine v sklepih in mišicah, nenormalno delovanje jeter, zvišane vrednosti kalija v krvi,
HOW TO STORE APROVEL
SHRANJEVANJE ZDRAVILA APROVEL
Do not use Aprovel after the expiry date which is stated on the carton and on the blister after EXP.
Zdravila Aprovel ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli ali pretisnem omotu poleg oznake "Upor. do:".
What Aprovel contains The active substance is irbesartan.
Kaj vsebuje zdravilo Aprovel Zdravilna učinkovina je irbesartan.
What Aprovel looks like and contents of the pack Aprovel 75 mg tablets are white to off-white, biconvex, and oval-shaped with a heart debossed on one side and the number 2771 engraved on the other side.
Na eni strani imajo vtisnjeno srce, na drugi pa vrezano številko 2771.
SANOFI WINTHROP INDUSTRIE 1, rue de la Vierge Ambarès & Lagrave F-33565 Carbon Blanc Cedex - France
SANOFI WINTHROP INDUSTRIE 1, rue de la Vierge Ambarès & Lagrave F- 33565 Carbon Blanc Cedex - Francija
SANOFI SYNTHELABO LIMITED Edgefield Avenue - Fawdon Newcastle Upon Tyne, Tyne & Wear NE3 3TT - United Kingdom
SANOFI SYNTHELABO LIMITED Edgefield Avenue - Fawdon Newcastle Upon Tyne, Tyne & Wear NE3 3TT - Velika Britanija
SANOFI WINTHROP INDUSTRIE 30-36 Avenue Gustave Eiffel, BP 7166 F-37071 Tours Cedex 2 - France
91 SANOFI WINTHROP INDUSTRIE 30- 36 Avenue Gustave Eiffel, BP 7166 F- 37071 Tours Cedex 2 - Francija
88 For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder.
92 Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
89 Latvija sanofi-aventis Latvia SIA Tel: +371 67 33 24 51
93 Latvija sanofi- aventis Latvia SIA Tel: +371 67 33 24 51
INFORMATION FOR THE USER Aprovel 150 mg tablets irbesartan
94 NAVODILO ZA UPORABO Aprovel 150 mg tablete irbesartan
91 Using other medicines Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
95 Uporaba drugih zdravil Obvestite svojega zdravnika ali farmacevta, če jemljete ali ste pred kratkim jemali katerokoli zdravilo, tudi če ste ga dobili brez recepta.
Patients with high blood pressure The usual dose is 150 mg once a day.
Bolniki z visokim krvnim tlakom Običajen odmerek je 150 mg enkrat na dan.
Patients with high blood pressure and type 2 diabetes with kidney disease In patients with high blood pressure and type 2 diabetes, 300 mg (two tablets a day) once daily is the preferred maintenance dose for the treatment of associated kidney disease.
96 Priporočeni vzdrževalni odmerek za zdravljenje bolezni ledvic, povezane z visokim krvnim tlakom in sladkorno boleznijo tipa 2, je 300 mg (dve tableti) enkrat na dan.
92 The doctor may advise a lower dose, especially when starting treatment in certain patients such as those on haemodialysis, or those over the age of 75 years.
Nekaterim bolnikom, kot so bolniki, ki se zdravijo s hemodializo, in bolniki, starejši od 75 let, lahko zdravnik predpiše manjši odmerek, še posebej na začetku zdravljenja.
What Aprovel looks like and contents of the pack Aprovel 150 mg tablets are white to off-white, biconvex, and oval-shaped with a heart debossed on one side and the number 2772 engraved on the other side.
Na eni strani imajo vtisnjeno srce, na drugi pa vrezano številko 2772.
SANOFI WINTHROP INDUSTRIE 30-36 Avenue Gustave Eiffel, BP 7166 F-37071 Tours Cedex 2 - France
98 SANOFI WINTHROP INDUSTRIE 30- 36 Avenue Gustave Eiffel, BP 7166 F- 37071 Tours Cedex 2 - Francija
94 For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder.
99 Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
95 Latvija sanofi-aventis Latvia SIA Tel: +371 67 33 24 51
100 Latvija sanofi- aventis Latvia SIA Tel: +371 67 33 24 51
INFORMATION FOR THE USER Aprovel 300 mg tablets irbesartan
101 NAVODILO ZA UPORABO Aprovel 300 mg tablete irbesartan
97 Using other medicines Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
102 Uporaba drugih zdravil Obvestite svojega zdravnika ali farmacevta, če jemljete ali ste pred kratkim jemali katerokoli zdravilo, tudi če ste ga dobili brez recepta.
Patients with high blood pressure and type 2 diabetes with kidney disease In patients with high blood pressure and type 2 diabetes, 300 mg once daily is the preferred maintenance dose for the treatment of associated kidney disease.
103 Priporočeni vzdrževalni odmerek za zdravljenje bolezni ledvic, povezane z visokim krvnim tlakom in sladkorno boleznijo tipa 2, je 300 mg enkrat na dan.
98 The doctor may advise a lower dose, especially when starting treatment in certain patients such as those on haemodialysis, or those over the age of 75 years.
Nekaterim bolnikom, kot so bolniki, ki se zdravijo s hemodializo, in bolniki, starejši od 75 let, lahko zdravnik predpiše manjši odmerek, še posebej na začetku zdravljenja.
What Aprovel looks like and contents of the pack Aprovel 300 mg tablets are white to off-white, biconvex, and oval-shaped with a heart debossed on one side and the number 2773 engraved on the other side.
Na eni strani imajo vtisnjeno srce, na drugi pa vrezano številko 2773.
SANOFI WINTHROP INDUSTRIE 30-36 Avenue Gustave Eiffel, BP 7166 F-37071 Tours Cedex 2 - France
105 SANOFI WINTHROP INDUSTRIE 30- 36 Avenue Gustave Eiffel, BP 7166 F- 37071 Tours Cedex 2 - Francija
100 For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder.
106 Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
INFORMATION FOR THE USER Aprovel 75 mg film-coated tablets irbesartan
108 NAVODILO ZA UPORABO Aprovel 75 mg filmsko obložene tablete irbesartan
103 Using other medicines Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
109 Uporaba drugih zdravil Obvestite svojega zdravnika ali farmacevta, če jemljete ali ste pred kratkim jemali katerokoli zdravilo, tudi če ste ga dobili brez recepta.
Patients with high blood pressure and type 2 diabetes with kidney disease In patients with high blood pressure and type 2 diabetes, 300 mg (four tablets a day) once daily is the preferred maintenance dose for the treatment of associated kidney disease.
110 Priporočeni vzdrževalni odmerek za zdravljenje bolezni ledvic, povezane z visokim krvnim tlakom in sladkorno boleznijo tipa 2, je 300 mg (štiri tablete) enkrat na dan.
104 The doctor may advise a lower dose, especially when starting treatment in certain patients such as those on haemodialysis, or those over the age of 75 years.
Nekaterim bolnikom, kot so bolniki, ki se zdravijo s hemodializo, in bolniki, starejši od 75 let, lahko zdravnik predpiše manjši odmerek, še posebej na začetku zdravljenja.
If you accidentally take too many tablets, contact your doctor immediately.
Če ste vzeli večji odmerek zdravila Aprovel, kot bi smeli Če ste pomotoma vzeli preveč tablet, se nemudoma posvetujte s svojim zdravnikom.
If you accidentally miss a daily dose, just take the next dose as normal.
Če ste pozabili vzeti zdravilo Aprovel Če ste pozabili vzeti dnevni odmerek, vzemite le naslednji predvideni odmerek ob običajnem času.
What Aprovel looks like and contents of the pack Aprovel 75 mg film-coated tablets are white to off-white, biconvex, and oval-shaped with a heart debossed on one side and the number 2871 engraved on the other side.
Na eni strani imajo vtisnjeno srce, na drugi pa vrezano številko 2871.
SANOFI WINTHROP INDUSTRIE 30-36 Avenue Gustave Eiffel, BP 7166 F-37071 Tours Cedex 2 - France
112 SANOFI WINTHROP INDUSTRIE 30- 36 Avenue Gustave Eiffel, BP 7166 F- 37071 Tours Cedex 2 - Francija
106 For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder.
113 Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
107 Latvija sanofi-aventis Latvia SIA Tel: +371 67 33 24 51
114 Latvija sanofi- aventis Latvia SIA Tel: +371 67 33 24 51
INFORMATION FOR THE USER Aprovel 150 mg film-coated tablets irbesartan
115 NAVODILO ZA UPORABO Aprovel 150 mg filmsko obložene tablete irbesartan
109 Using other medicines Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
116 Uporaba drugih zdravil Obvestite svojega zdravnika ali farmacevta, če jemljete ali ste pred kratkim jemali katerokoli zdravilo, tudi če ste ga dobili brez recepta.
Patients with high blood pressure and type 2 diabetes with kidney disease In patients with high blood pressure and type 2 diabetes, 300 mg (two tablets a day) once daily is the preferred maintenance dose for the treatment of associated kidney disease.
117 Priporočeni vzdrževalni odmerek za zdravljenje bolezni ledvic, povezane z visokim krvnim tlakom in sladkorno boleznijo tipa 2, je 300 mg (dve tableti) enkrat na dan.
110 The doctor may advise a lower dose, especially when starting treatment in certain patients such as those on haemodialysis, or those over the age of 75 years.
Nekaterim bolnikom, kot so bolniki, ki se zdravijo s hemodializo, in bolniki, starejši od 75 let, lahko zdravnik predpiše manjši odmerek, še posebej na začetku zdravljenja.
What Aprovel looks like and contents of the pack Aprovel 150 mg film-coated tablets are white to off-white, biconvex, and oval-shaped with a heart debossed on one side and the number 2872 engraved on the other side.
Na eni strani imajo vtisnjeno srce, na drugi pa vrezano številko 2872.
SANOFI WINTHROP INDUSTRIE 30-36 Avenue Gustave Eiffel, BP 7166 F-37071 Tours Cedex 2 - France
119 SANOFI WINTHROP INDUSTRIE 30- 36 Avenue Gustave Eiffel, BP 7166 F- 37071 Tours Cedex 2 - Francija
112 For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder.
120 Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
113 Latvija sanofi-aventis Latvia SIA Tel: +371 67 33 24 51
121 Latvija sanofi- aventis Latvia SIA Tel: +371 67 33 24 51
INFORMATION FOR THE USER Aprovel 300 mg film-coated tablets irbesartan
122 NAVODILO ZA UPORABO Aprovel 300 mg filmsko obložene tablete irbesartan
115 Using other medicines Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
123 Uporaba drugih zdravil Obvestite svojega zdravnika ali farmacevta, če jemljete ali ste pred kratkim jemali katerokoli zdravilo, tudi če ste ga dobili brez recepta.
Patients with high blood pressure and type 2 diabetes with kidney disease In patients with high blood pressure and type 2 diabetes, 300 mg once daily is the preferred maintenance dose for the treatment of associated kidney disease.
124 Priporočeni vzdrževalni odmerek za zdravljenje bolezni ledvic, povezane z visokim krvnim tlakom in sladkorno boleznijo tipa 2, je 300 mg enkrat na dan.
116 The doctor may advise a lower dose, especially when starting treatment in certain patients such as those on haemodialysis, or those over the age of 75 years.
Nekaterim bolnikom, kot so bolniki, ki se zdravijo s hemodializo, in bolniki, starejši od 75 let, lahko zdravnik predpiše manjši odmerek, še posebej na začetku zdravljenja.
What Aprovel looks like and contents of the pack Aprovel 300 mg film-coated tablets are white to off-white, biconvex, and oval-shaped with a heart debossed on one side and the number 2873 engraved on the other side.
Na eni strani imajo vtisnjeno srce, na drugi pa vrezano številko 2873.
SANOFI WINTHROP INDUSTRIE 30-36 Avenue Gustave Eiffel, BP 7166 F-37071 Tours Cedex 2 - France
126 SANOFI WINTHROP INDUSTRIE 30- 36 Avenue Gustave Eiffel, BP 7166 F- 37071 Tours Cedex 2 - Francija
118 For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder.
127 Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
119 Latvija sanofi-aventis Latvia SIA Tel: +371 67 33 24 51
128 Latvija sanofi- aventis Latvia SIA Tel: +371 67 33 24 51
120
129
What is APTIVUS?
Kaj je zdravilo APTIVUS?
APTIVUS is a medicine containing the active substance tipranavir.
APTIVUS je zdravilo, ki vsebuje zdravilno učinkovino tipranavir.
It is available as pink capsules (250 mg).
Na voljo je v obliki kapsul rožnate barve (250 mg).
What is APTIVUS used for?
Za kaj se zdravilo APTIVUS uporablja?
APTIVUS is an antiviral medicine.
Zdravilo APTIVUS je protivirusno zdravilo.
It is used in combination with ritonavir (another antiviral medicine) and other antiviral medicines to treat adult patients with human immunodeficiency virus type 1 (HIV-1), a virus that causes acquired immune deficiency syndrome (AIDS).
Uporablja se v kombinaciji z ritonavirjem (drugim protivirusnim zdravilom) in drugimi protivirusnimi zdravili pri zdravljenju odraslih, okuženih z virusom humane imunske pomanjkljivosti tipa 1 (HIV- 1), virusom, ki povzroča sindrom pridobljene imunske pomanjkljivosti (AIDS).
APTIVUS is used in patients who have already been treated with other antiviral medicines for HIV infection, and in whom many medicines in the same class as APTIVUS (protease inhibitors) do not work.
Zdravilo APTIVUS se uporablja pri bolnikih, ki so se zaradi okužbe s HIV že zdravili z drugimi protivirusnimi zdravili in pri katerih številna zdravila istega razreda kot zdravilo APTIVUS (zaviralci proteaze) ne učinkujejo.
Doctors should only prescribe APTIVUS once they have looked at the antiviral medicines the patient has taken before and the likelihood that the virus will respond to the medicine.
Zdravniki smejo predpisati zdravilo APTIVUS šele potem, ko se seznanijo s protivirusnimi zdravili, ki jih je bolnik jemal prej, in verjetnostjo, da se bo virus odzval na zdravilo.
How is APTIVUS used?
Kako se zdravilo APTIVUS uporablja?
Treatment with APTIVUS should be initiated by a doctor who has experience in the treatment of HIV-1 infection.
Zdravljenje z zdravilom APTIVUS mora uvesti zdravnik z izkušnjami pri zdravljenju okužb s HIV- 1.
The recommended dose of APTIVUS is 500 mg twice a day.
Priporočen odmerek zdravila APTIVUS znaša 500 mg dvakrat dnevno.
Each dose must be taken with 200 mg ritonavir and food.
Vsak odmerek je treba vzeti z 200 mg ritonavirja in hrano.
It should be used with caution in patients who have mild liver problems and should not be used in patients who have moderate or severe liver problems.
Pri bolnikih z blagimi težavami z jetri ga je treba uporabljati previdno, ne sme pa se ga uporabljati pri bolnikih z zmernimi ali resnimi težavami z jetri.
How does APTIVUS work?
Kako zdravilo APTIVUS deluje?
The active substance in APTIVUS, tipranavir, is a protease inhibitor.
Zdravilna učinkovina zdravila APTIVUS, tipranavir, je zaviralec proteaze.
It blocks an enzyme (protease) that is involved in the reproduction of HIV.
Blokira encim (proteazo), ki sodeluje pri razmnoževanju HIV- a.
When the enzyme is blocked, the virus does not reproduce normally, slowing down the spread of infection.
Ko je encim blokiran, se virus ne razmnožuje normalno, kar upočasni širjenje okužbe.
Ritonavir is another protease inhibitor that is used as a ‘ booster’.
Ritonavir je drug zaviralec proteaze, ki se uporablja kot „ stopnjevalec “.
It slows down the rate at which tipranavir is broken down, increasing the levels of tipranavir in the blood.
Le - ta upočasnjuje hitrost razgradnje tipranavirja in povečuje koncentracije tipranavira v krvi.
This allows a lower dose of tipranavir to be used for the same antiviral effect.
To omogoča, da za dosego enakega protivirusnega učinka zadošča manjši odmerek tipranavira.
APTIVUS, taken in combination with other antiviral medicines, reduces the amount of HIV in the blood and keeps it at a low level.
Zdravilo APTIVUS, če ga jemljemo v kombinaciji z drugimi protivirusnimi zdravili, zmanjša količino virusa HIV v krvi in ga ohranja na nizki ravni.
APTIVUS does not cure HIV infection or AIDS, but it may delay the damage to the immune system and the development of infections and diseases associated with AIDS.
Zdravilo APTIVUS ne ozdravi okužbe s HIV ali AIDS- a, vendar pa lahko upočasni slabšanja imunskega sistema in razvoj okužb in bolezni, povezanih z AIDS - om.
(44-20) 74 18 84 00 Fax (44-20) 74 18 84 16 E-mail: mail@emea. europa. eu http: / /www. emea. europa. eu ©EMEA 2007 Reproduction and/ or distribution of this document is authorised for non commercial purposes only provided the EMEA is acknowledged including a protease inhibitor.
(44- 20) 74 18 84 00 Fax (44- 20) 74 18 84 16 E- mail: mail@ emea. europa. eu http: // www. emea. europa. eu ©EMEA 2007 Reproduction and/ or distribution of this document is authorised for non commercial purposes only provided the EMEA is acknowledged Kako je bilo zdravilo APTIVUS raziskano?
Both studies compared the effects of APTIVUS to those of another protease inhibitor chosen on the basis of the patient ’ s previous treatments and predicted response.
Zdravilo APTIVUS so preučevali v dveh glavnih študijah s 1. 177 odraslimi, ki so predhodno prejemali številna različna protivirusna zdravila, vendar se niso odzivali na svojo trenutno terapevtsko kombinacijo, ki je vključevala zaviralec proteaze.
Each patient also took ritonavir and a combination of other anti-HIV medicines that were chosen as they had the best chances of reducing the levels of HIV in their blood.
Vsak bolnik je jemal tudi ritonavir in kombinacijo drugih zdravil proti virusu HIV, izbranih tako, da so obetala največjo verjetnost za zmanjšanje ravni virusa HIV v njihovi krvi.
The results of the main measures of effectiveness (the number of patients in whom treatment had been successful and the average time to the failure of treatment) were not available at the time of the assessment, so the company presented information on the change in the levels of HIV in the patients’ blood (viral load) after 24 weeks of treatment.
Rezultati glavnih meril učinkovitosti (število bolnikov, pri katerih je bilo zdravljenje uspešno, in povprečen čas do odpovedi zdravljenja) v trenutku ocenjevanja niso bili na voljo, zato je podjetje predstavilo informacije o spremembi ravni virusa HIV v krvi bolnikov (virusne obremenitve) po 24 tednih zdravljenja.
The studies were still ongoing at the time of the medicine’ s assessment.
Študije so v trenutku ocenjevanja zdravila še potekale.
What benefit has APTIVUS shown during the studies?
Kakšne koristi je zdravilo APTIVUS izkazalo med raziskavami?
APTIVUS, taken in combination with ritonavir, was more effective than the comparator medicines at reducing viral loads in patients with few remaining options for successful HIV treatment.
Zdravilo APTIVUS, dajano v kombinaciji z ritonavirjem, je bilo pri zmanjševanju virusnih obremenitev pri bolnikih z le malo preostalimi možnostmi za uspešno zdravljenje HIV učinkovitejše od primerjalnih zdravil.
In the two studies taken together, 240 (41.2%) of the 582 patients taking APTIVUS had achieved and maintained a reduction in viral load of at least 90%, compared with 109 (18.9%) of the 577 taking the comparator protease inhibitors.
V obeh študijah skupaj je 240 (41, 2%) od 582 bolnikov, ki so jemali zdravilo APTIVUS, doseglo in ohranjalo zmanjšanje virusne obremenitve za najmanj 90%, v primerjavi s 109 (18, 9%) od 577 bolnikov, ki so jemali primerjalne zaviralce proteaze.
What is the risk associated with APTIVUS?
Kakšna tveganja so povezana z zdravilom APTIVUS?
The most common side effects when taking APTIVUS with ritonavir (seen in more than 1 patient in 10) are diarrhoea and nausea (feeling sick).
Najpogostejša neželena učinka pri jemanju zdravila APTIVUS z ritonavirjem (opažena pri več kot 1 bolniku od 10) sta driska in slabost.
For the full list of all side effects reported with APTIVUS, see the Package Leaflet.
Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila APTIVUS, glejte Navodilo za uporabo.
APTIVUS should not be used in people who may be hypersensitive (allergic) to tipranavir or any of the other ingredients.
Zdravila APTIVUS se ne sme uporabljati pri osebah, ki utegnejo biti preobčutljive za (alergične na) tipranavir ali katero koli drugo sestavino zdravila.
APTIVUS should not be used in patients with moderate or severe problems with their liver or who are taking any of the following medicines: • rifampicin (used to treat tuberculosis), • St John’ s wort (a herbal preparation used to treat depression), • medicines that are broken down in the same way as APTIVUS or ritonavir and are harmful at high levels in the blood.
Zdravila APTIVUS se ne sme uporabljati pri bolnikih, ki imajo zmerne ali hude težave z jetri oz. ki jemljejo katero od naslednjih zdravil: • rifampicin (uporablja se za zdravljenje tuberkuloze), • šentjanževka (zeliščni pripravek, ki se uporablja za zdravljenje depresije), • zdravila, katerih razgradnja poteka na enak način kot razgradnja zdravila APTIVUS ali ritonavirja ter so škodljiva, kadar so njihove ravni v krvi visoke.
See the Package Leaflet for the full list of these medicines.
Za celoten seznam teh zdravil glejte Navodilo za uporabo.