natgillin/translations-raw huggingface dataset:
If you know that you are allergic (hypersensitive) to any of the ingredients or if you become so, you must not use Betaferon.
Če veste, da ste alergični na (preobčutljivi za) katerokoli sestavino zdravila ali nanje postanete preobčutljivi, zdravila Betaferon ne smete uporabljati.
3.
82 3.
Always use Betaferon exactly as your doctor has instructed you.
Pri uporabi zdravila Betaferon natančno upoštevajte zdravnikova navodila.
82 Dose:
Odmerek
Every other day (once every two days), 1.0 ml of the prepared Betaferon solution (see Annex) injected under the skin (subcutaneously).
Vsak drugi dan (enkrat na dva dni) 1 ml pripravljene raztopine zdravila Betaferon (glejte Dodatek) injicirane pod kožo (subkutano).
This equals 250 microgram (8 million IU) Interferon beta-1b.
To ustreza 250 mikrogramom (8 milijonov i. e.) interferona beta- 1b.
In general, treatment should be started at a low dose of 0.25 ml (62.5 micrograms).
Odmerek vam bodo nato postopoma večali do končnega odmerka 1 ml (250 mikrogramov).
Your doses will then be increased gradually to the full dose of 1.0 ml (250 micrograms).
Odmerek je treba povečati v štirih korakih, ob vsaki četrti injekciji (0, 25 ml, 0, 5 ml, 0, 75 ml, 1 ml).
The dose should be increased at every fourth injection in four steps (0.25 ml, 0.5 ml, 0.75 ml, 1.0 ml).
Pred injiciranjem je treba raztopino zdravila Betaferon pripraviti iz viale s praškom zdravila Betaferon in 1, 2 ml vehikla iz napolnjene injekcijske brizge.
Your doctor may decide together with you to change the time intervals for dose increase depending on side effects you may experience at the start of treatment.
To bodo naredili bodisi zdravnik ali njegovo osebje bodisi vi sami, potem ko se boste za to zadostno usposobili.
Preparing the injection:
To navodilo opisuje tudi pripravo raztopine zdravila Betaferon za injiciranje.
Before injection, the Betaferon solution has to be prepared from a vial of Betaferon powder and 1.2 ml of liquid from the pre-filled solvent syringe.
Mesto injiciranja morate redno menjavati (glejte poglavje Bodite posebno pozorni pri uporabi zdravila Betaferon in upoštevajte navodila Menjavanje mest injiciranja v Dodatku tega navodila).
This will either be done by your doctor or his/her assistant or by yourself after you have been carefully trained.
O trajanju zdravljenja se bo zdravnik odločil skupaj z vami.
Detailed instructions for self-injection of Betaferon under the skin are provided in the Annex at the back of this leaflet.
Uporaba odmerka zdravila Betaferon, ki je večkrat presegel odmerek priporočen za zdravljenje multiple skleroze, ni vodila do življenjsko ogrožujočih stanj.
The se instructions also tell you how to prepare the Betaferon solution for injection.
Posvetujte se z zdravnikom, če ste si injicirali preveč zdravila Betaferon ali če ste si ga injicirali prepogosto.
The injection site must be changed regularly.
Če ste pozabili vzeti zdravilo Betaferon
See ’Take special care with Betaferon’ and follow the instructions under ’Rotating injection sites’ in the Annex at the back of this leaflet.
Če si zdravilo pozabite samoinjicirati ob določenem času, to storite takoj, ko se spomnite in nato ponovno čez 48 ur.
At present it is not known how long treatment with Betaferon should last.
Ne injicirajte si dvojnega odmerka, če ste pozabili vzeti prejšnji odmerek.
The length of treatment will be decided by your doctor together with you.
83 Če ste prenehali uporabljati zdravilo Betaferon
If you use more Betaferon than you should:
Če nehate uporabljati zdravilo Betaferon, ni pričakovati akutnih odtegnitvenih simptomov.
Giving many times the dose of Betaferon recommended for the treatment of multiple sclerosis has not led to life-threatening situations.
► Če imate dodatna vprašanja o uporabi zdravila, se posvetujte z zdravnikom ali s farmacevtom.
Talk to your doctor if you inject too much Betaferon or injected too often.
Kot vsa zdravila ima lahko tudi zdravilo Betaferon neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
If you forget to use Betaferon:
Na začetku zdravljenja so neželeni učinki pogosti, a z nadaljevanjem zdravljenja praviloma izzvenijo.
If you have forgotten to give yourself an injection at the right time do it as soon as you remember and then follow on with the next one 48 hours later.
Te simptome je mogoče ublažiti z jemanjem paracetamola ali nesteroidnih protivnetnih zdravil, kot je na primer ibuprofen.
Do not inject a double dose to make up for a forgotten individual dose.
Za več informacij se pogovorite s svojim zdravnikom.
If you stop using Betaferon:
Kako uporabljati zdravilo Betaferon).
Talk to your doctor if you stop or wish to stop treatment.
Zdravilo Betaferon lahko povzroči tudi resne neželene učinke.
Stopping Betaferon is not known to cause acute withdrawal symptoms.
Če katerikoli neželeni učinek postane resen ali če opazite katerikoli neželeni učinek, ki ni omenjen v tem navodilu, obvestite svojega zdravnika ali farmacevta.
► If you have any further questions on the use of this product, ask your doctor or pharmacist.
► Zdravnika nemudoma obvestite in prenehajte uporabljati zdravilo Betaferon:
Like all medicines, Betaferon can cause side effects, although not everybody gets them.
če se pojavijo simptomi, kot je srbenje po vsem telesu, otekanje obraza in/ ali jezika ali nenadna kratka sapa,
At the beginning of treatment side effects are common but in general they become less with further treatment.
če se počutite izrazito bolj žalostni ali brezupno, kot ste se pred začetkom zdravljenja z zdravilom Betaferon, ali če se vam pojavijo samomorilne misli,
These symptoms may be reduced by taking paracetamol or non-steroidal anti-inflammatory medicines such as ibuprofen.
če opazite kakršnekoli nenavadne modrice, čezmerne krvavitve po poškodbi ali če se vam zdi, da pogosto zbolevate za okužbami,
Symptoms can be redness, swelling, discoloration, inflammation, pain, hypersensitivity, necrosis.
če izgubite apetit, ste utrujeni, vam je slabo (navzeja), se pojavi ponavljajoče se bruhanje, predvsem, če opazite srbenje po vsem telesu, rumeno obarvanje kože in očesnih beločnic ter nagnjenost k podplutbam,
See ‘Take special care’ in section 2 for more information and what to do, if you experience an injection site reaction.
če imate simptome, kot so nepravilen srčni utrip, otekanje gležnjev ali nog ali kratka sapa,
Please talk to your doctor for further information.
če imate bolečine v trebuhu, ki se širijo v hrbet, in/ ali vam je slabo ali imate zvišano telesno temperaturo.
To reduce side effects at the start of treatment, your doctor should start you on a low dose of Betaferon and increase it gradually (see section 3. ‘How to use Betaferon’).
84 Naslednji seznam neželenih učinkov temelji na poročilih iz kliničnih preskušanj z zdravilom Betaferon (preglednica 1) in neželenih učinkih, o katerih so poročali po začetku trženja zdravila (preglednica 2).
Betaferon may also cause serious side effects.
(neželeni učinki, ki so se v kliničnih preskušanjih zdravila Betaferon pojavili zelo pogosto (≥ 10% primerov) in v višjem odstotku kot pri placebu.
If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
V preglednici so tudi neželeni učinki, ki se pojavljajo pri manj kot 10% primerov, a so pomembno povezani z zdravljenjem).
► Tell your doctor immediately and stop using Betaferon:
- zmanjšanje števila belih krvnih celic, otekanje bezgavk
− if you experience symptoms such as itching all over your body, swelling of your face and/or your tongue or sudden shortness of breath.
- znižanje vrednosti sladkorja v krvi
− if you feel noticeably more sad or hopeless than before the treatment with Betaferon, or if you develop thoughts of suicide.
- glavobol, omotica, nespečnost, migrena, otrplost ali občutek ščemenja (parestezija)
− if you notice any unusual bruising, excessive bleeding after injury or if you seem to be catching a lot of infections.
- vnetje očesne veznice, motnje vida
− if you have loss of appetite, fatigue, feeling sick (nausea), repeated vomiting, especially if you notice widespread itching, yellowing of the skin, or of the whites of the eyes or easy bruising.
- bolečine v ušesu
− if you experience symptoms like irregular heart beat, swelling such as of the ankles or legs, or shortness of breath.
- nepravilno, hitro bitje ali utripanje srca (palpitacije)
− if you notice pain in your belly which is radiating to your back, and/or you feel sick or have a fever.
- rdečica in/ ali vročinski oblivi obraza zaradi širjenja žil, zvišan krvni tlak
The following side effects listing is based on reports from clinical trials with Betaferon (table 1) and from side effects reported on the marketed product (table 2).
- izcedek iz nosu, kašelj, hripavost zaradi okužbe zgornjih dihal, vnetje sinusov, močnejši kašelj,
Table 1:
kratka sapa
(side effects which have occurred in clinical trials with Betaferon very commonly (at a percentage of ≥ 10% of the cases) and at a higher percentage than those observed with placebo.
- driska, zaprtost, slabost, bruhanje, bolečine v trebuhu
The table also includes side effects which occur in less than 10% but were significantly associated with the treatment)
- povečane vrednosti jetrnih encimov v krvi (pokažejo krvne preiskave)
- infection, abscess
- bolezni kože, osip
- reduced number of white blood cells, swollen lymph glands
- otrdelost mišic (hipertonija), bolečina v mišicah (mialgija), mišična šibkost (miastenija),
- decrease of sugar in the blood
bolečina v hrbtu, bolečine v okončinah, npr. v prstih na nogah in rokah
- depression, anxiety
- zastoj seča (retencija urina), beljakovine v seču (pokažejo urinske preiskave), pogosto
- headache, dizziness, sleeplessness, migraine, numbness or tingling feeling (paresthesia)
- boleče mesečne krvavitve (menstruacija), menstruacijske motnje, močne krvavitve iz
- conjunctivitis, abnormal vision
- reakcije na mestu injiciranja (vključno z rdečico, otekanjem, spremembo barve kože, vnetjem,
- ear pain
Preglednica 2:
- irregular, rapid beating or pulsation of the heart (palpitation)
neželeni učinki, zabeleženi v obdobju trženja zdravila (spontano poročanje):
- redness and/or facial flushing due to widening of blood vessels, increased blood pressure
► zelo pogosti neželeni učinki (verjetno jih bo imel več kot 1 od 10 uporabnikov):
- runny nose, cough, hoarseness due to infection of the upper respiratory tract, sinusitis,
- gripi podobni simptomi *
84 cough increased, shortness of breath
- zvišana telesna temperatura *
- diarrhoea, constipation, nausea, vomiting, abdominal pain
- reakcije na mestu injiciranja *
- rises in the blood levels of liver enzymes (will show up in blood tests)
- vnetje na mestu injiciranja *
- skin disorder, rash
- bolečina na mestu injiciranja *
- muscle stiffness (hypertonia), painful muscles (myalgia), muscular debility (myasthenia), back
(* pogostost temelji na podatkih iz kliničnih preskušanj)
pain, pain in extremities such as fingers and toes
► pogosti neželeni učinki (verjetno jih bo imelo 1 do 10 od 100 uporabnikov):
- holding urine (urine retention), protein in the urine (will show up in urine tests)
- razkroj kože in odmrtje tkiva (nekroza) na mestu injiciranja *
urinary frequency, urinary incontinence, urinary urgency
(* pogostost temelji na podatkih iz kliničnih preskušanj)
- painful periods (menstruation), menstrual disorder, heavy uterine bleeding especially between
- zmanjša se lahko število belih in rdečih krvnih celic, pa tudi število trombocitov (ki
menstrual periods, impotence
pomagajo pri strjevanju krvi)
- injection site reaction (including redness, swelling, discolouration, inflammation, pain, allergic
- zvišan krvni tlak
reaction (hypersensitivity), see ‘Take special care with Betaferon’), skin breakdown and tissue destruction (necrosis) at injection site (see ‘Take special care with Betaferon’), flu -like symptoms, fever, pain, chest pain, accumulation of fluid in arm, leg or face, lack/loss of strength, chills, sweating, malaise
- slabost
Table 2:
- bruhanje
side effects reports on the marketed product (from spontaneous reporting):
- spremembe jetrnih testov (povečane vrednosti jetrnih encimov v krvi)
► Very common side effects (more than 1 user in 10 are likely to get these):
- otekli in običajno srbeči deli kože ali sluznice (urtikarija)
- flu-like symptoms*,
- osip
- chills*,
- srbenje (pruritus)
- fever*,
- izpadanje las
- injection site reaction*,
- bolečina v mišicah
- injection site inflammation*,
- otrplost mišic
- injection site pain*.
- otekle bezgavke
(*frequencies based on clinical trials)
- resne alergijske (preobčutljivostne) reakcije
► Common side effects (1 to 10 users in 100 are likely to get these):
- nepravilno delovanje ščitnice (proizvaja se premalo ali preveč hormona)
- skin breakdown and tissue destruction (necrosis) at injection site*
- povečajo se lahko vrednosti določenih vrst maščob v krvi (trigliceridi), glejte poglavje Bodite
(*frequencies based on clinical trials)
posebno pozorni pri uporabi zdravila Betaferon (pokaže se pri krvnih preiskavah)
► Uncommon side effects (1 to 10 users in 1,000 are likely to get these):
- izguba apetita, ki povzroči zmanjšanje telesne mase (anoreksija)
- the number of white cells and red cells in the blood may fall, the number of platelets
- nihanja v razpoloženju
(which help the blood to clot) may fall,
- poskusi samomora
- depression,
- konvulzije
- increase of blood pressure,
- obolenje srčne mišice (kardiomiopatija)
- nausea,
- hitrejši srčni utrip
- vomiting,
- kratka sapa (dispneja)
- liver test may change (rises in the blood levels of enzymes the liver produces),
- pankreatitis, glejte poglavje Bodite posebno pozorni pri uporabi zdravila Betaferon
- swollen and usually itching patches of skin or mucous membranes (urticaria),
- poveča se lahko vrednost specifičnega jetrnega encima (gama GT) in rdečkasto rumenega
- rash,
- hepatitis
- itching (pruritus),
- sprememba barve kože
- loss of scalp hair,
- motnje menstruacije
- painful muscles,
- bolečine v prsnem košu
- muscle stiffness.
- splošno slabo počutje
► Rare side effects (1 to 10 users in 10,000 are likely to get these):
- potenje
- swollen lymph glands,
- izguba telesne mase
- serious allergic (hypersensitivity) reactions,
Shranjevanje zdravila Betaferon
- the thyroid gland does not work properly (too much or too little hormone is produced),
Ne zamrzujte.
- a certain type of blood fats (triglycerides) may increase, see ‘Take special care with Betaferon’
Zdravila Betaferon ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na ovojnini.
(will show up in blood tests),
Po pripravi je treba raztopino nemudoma uporabiti.
- severe loss of appetite leading to weight loss (anorexia),
Zdravilo shranjujte nedosegljivo otrokom!
85
86 Ne uporabljajte zdravila Betaferon, če opazite, da vsebuje delce ali je obarvano.
- confusion,
Takšni ukrepi pomagajo varovati okolje.
- anxiety,
Dodatne informacije
- mood swings,
Kaj vsebuje zdravilo Betaferon
- suicide attempt,
Pomožne snovi so
- convulsion,
− −
- disease of the heart muscle (cardiomyopathy),
Po rekonstituciji vsebuje vsak mililiter 250 mikrogramov (8 milijonov i. e.) interferona beta- 1b.
- f aster heart beat,
Izgled zdravila Betaferon in vsebina pakiranja
- irregular, rapid beating or pulsation of the heart (palpitation),
Zdravilo Betaferon je sterilen bel do belkast prašek za raztopino za injiciranje.
- sudden shortness of breath (bronchospasm),
Zdravilo Betaferon je na voljo v pakiranjih, ki vsebujejo:
- shortness of breath (dyspnea),
Imetnik dovoljenja za promet z zdravilom in izdelovalec:
- pancreatitis, see ‘Take special care with Betaferon’,
Bayer Schering Pharma AG, D- 13342 Berlin, Nemčija
- a specific liver enzyme (gamma GT) and a reddish yellow pigment (bilirubin), which is
87 Za vse morebitne nadaljnje informacije o tem zdravilu se lahko obrnete na predstavništvo imetnika dovoljenja za promet z zdravilom.
produced by your liver, may rise (this will show up in blood tests),
België/ Belgique/ Belgien
- hepatitis,
Bayer S. A. / N. V.
- skin discoloration,
Tel. + 32 (0) 2- 535 63 11
- menstrual disorders,
България
- chest pain,
тел. + 359 02 81 401 01
- malaise,
Česká republika
- sweating,
Bayer s. r. o.
- loss of weight.
Tel: +420 2 71 73 06 61
5.
Danmark
How to store Betaferon
Bayer A/ S
Do not store above 25°C.
Tel. + 45 45 235000
Do not freeze.
Deutschland
Do not use after the expiry date which is stated on the pack.
Bayer Vital GmbH
After preparing the solution you should use it immediately.
Tel. +49 (0) 214- 30 513 48
Keep out of the reach and sight of children.
Eesti
Do not use Betaferon if you notice it contains particles or is discoloured.
Bayer OÜ
The se measures will help to protect the environment.
Tel. +372 655 8565
Further information
Ελλάδα
What Betaferon contains:
Bayer Ελλάς ΑΒΕΕ
The active substance is Interferon beta-1b, 250 microgram per millilitre when reconstituted.
Τηλ. +30 210- 618 75 00
The other ingredients are − in the powder: mannitol and human albumin, − in the solvent (sodium chloride solution 5.4 mg/ml (0.54% (w/v)): sodium chloride, water for injections.
España.
After reconstitution each millilitre contains 2 50 microgram (8 million IU) interferon beta-1b.
Química Farmacéutica Bayer S. L.
The solvent for Betaferon is provided in a 1.2 ml pre-filled syringe and contains 1.2 ml sodium chloride solution 5.4 mg/ml (0.54% (w/v)).
Tel. + 34 93- 495 65 00
86 What Betaferon looks like and contents of the pack:
France
Betaferon is a sterile white to off-white powder for solution for injection.
Bayer Santé
Betaferon is available in pack sizes of:
Tel. +33 3 - 20 20 80 80
5 vials of Interferon beta-1b and 5 pre-filled syringes containing solvent (sodium chloride solution) or 15 vials of Interferon beta-1b and 15 pre-filled syringes containing solvent (sodium chloride solution).
Ireland
Marketing authorisation holder and manufacturer:
Bayer Limited
Bayer Schering Pharma AG, D-13342 Berlin, Germany
Tel. +353 1 2999313
87 For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder.
Icepharma
België/Belgique/Belgien България Česká republika
Tel: + 354 540 8000
Bayer S.A./N.V.
Bayer S. p. A.
Tel. + 32 (0)2-535 63 11 тел. + 359 02 81 401 01 Tel: +420 2 71 73 06 61
Tel. +39 02 397 81
France Ireland Ísland Italia Κύπρος Latvija Lietuva
Κύπρος
Bayer Santé Bayer Limited Icepharma Bayer S.p. A.
NOVAGEM Limited
Nederland Norge Österreich Polska Portugal România Slovenija Slovenská republika Suomi/Finland Sverige United Kingdom
Malta
88 Annex:
88 Dodatek:
SELF-INJECTION PROCEDURE
POSTOPEK SAMOINJICIRANJA
The following instructions are intended to explain how to prepare Betaferon for administration and how to inject Betaferon yourself.
Naslednja navodila pojasnjujejo, kako zdravilo Betaferon pripravite za uporabo in kako si ga sami injicirate.
Your doctor or their assistant will help you to learn the process of self-administration.
Zdravnik ali zdravstveno osebje vas bodo naučili postopka samoinjiciranja.
STEP BY STEP INSTRUCTIONS
NAVODILA PO KORAKIH
The instructions includes the following main steps:
Navodila obsegajo naslednje korake:
A) General advice B) Getting ready to inject C) Reconstituting the solution, step by step D) Drawing up the injection E) Making the injection F) Quick review of the process
A) Splošni nasveti B) Priprava na injiciranje C) Rekonstitucija raztopine po korakih D) Izvlek količine za injiciranje E) Priprava injekcije F) Kratek pregled postopka
• Get a good start!
• Dobro se pripravite!
You will find that within a few weeks your treatment will become a natural part of your routine.
Za podrobnosti glede pogojev shranjevanja glejte poglavje 5.
As you get started, you may find the following tips helpful:
Shranjevanje zdravila Betaferon v navodilu za uporabo.
− Set up a permanent storage area in a convenient location out of the reach of children so your Betaferon and other supplies are always easy to find. − For details on storing conditions see section 5. ‘How to store Betaferon’ of the leaflet.) − Try to take your injection at the same time of day.
Kako uporabljati zdravilo Betaferon v navodilu za uporabo.
This makes it easier to remember and easier to plan a block of time when you will not be interrupted. − Please refer to section 3. ‘How to use Betaferon’ of the leaflet for further details on how to use Betaferon. − Prepare each dose only when you are ready for an injection.
Ko pripravite zdravilo Betaferon,
After mixing Betaferon, you should administer the injection immediately (if Betaferon is not used immediately, see section 5. ‘How to store Betaferon’).
Shranjevanje zdravila Betaferon).
− Be consistent - use Betaferon as described in section 3. ‘How to use Betaferon’ of the leaflet.
Kako uporabljati
Always double-check your dosage. − Keep your syringes and syringe disposal unit out of the reach of children; lock the supplies if possible. − Never re-use syringes or needles. − Always use a sterile (aseptic) technique as described in here. − Always place the used syringes in the proper disposal unit.
- Brizge in posode za odstranjevanje brizg hranite zunaj dosega otrok; če je mogoče, hranite pribor
89 Important:
89 Pomembno:
Do not use any area where you can feel lumps, bumps, firm knots, pain or an area that is discoloured, indented, scabbed, or where the skin is broken.
Ne uporabljajte predelov, na katerih čutite zatrdline, bulice, čvrste vozliče, predelov, ki so boleči, ali predelov, na katerih je koža spremenjena, vdrta, pokrita s krastami ali ranjena.
Talk to your doctor or healthcare professional about these or any other unusual conditions you may find.
O vseh takšnih ali drugih neobičajnih spremembah, ki jih najdete, se posvetujte z zdravnikom ali drugim zdravstvenim delavcem.
Follow the sequence described in the schedule at the end of the Annex (see II) ‘Rotating injection sites’) and you will come back to your first injection site area after 8 injections (16 days).
Na prvo mesto injiciranja se boste vrnili po 8 injekcijah (16 dneh).
An example of a medication record is also included.
Priložen je primer zapisovanja o uporabi zdravila.
• Medication
• Zdravilo
You will need: • 1 Betaferon vial (with powder for solution for injection) • 1 pre-filled syringe of diluent for Betaferon (sodium chloride solution (0.54% (w/v)) • 21-gauge needle • 30-gauge needle • alcohol wipes In addition you will need a disposal unit for used syringes and needles.
Potrebujete: • 1 vialo zdravila Betaferon (s praškom za raztopino za injiciranje) • 1 napolnjeno injekcijsko brizgo z vehiklom za zdravilo Betaferon (0, 54% raztopina natrijevega klorida (m/ v)) • iglo velikosti 21 • iglo velikosti 30 • alkoholne blazinice Potrebovali boste tudi posodo za odstranjevanje uporabljenih brizg in igel.
C) Reconstituting the solution, step by step
C) Rekonstitucija raztopine po korakih
It is best to use your thumb rather than your nail as it could break.
Odprite jo s palcem.
Leave the wipe on top of the vial.
Vialo brišite samo v eni smeri.
4 – Take out the pre-filled diluent syringe from its package.
4 – Brizgo, napolnjeno z vehiklom, vzemite iz ovojnine.
5 - Take the 21-gauge needle out of its wrapping and place it firmly onto the tip (nozzle) of the syringe.
5 – Odstranite ovojnino z igle velikosti 21 in jo čvrsto pritrdite na konico (nastavek) brizge.
Do not touch the needle.
Igle se ne dotikajte.
6. - Holding the Betaferon vial on a stable surface, slowly insert the needle of the syringe (containing 1.2 ml of liquid) all the way through the stopper of the vial.
6. – Medtem ko viala z zdravilom Betaferon stoji na čvrsti podlagi počasi potisnite iglo brizge (ki vsebuje 1, 2 ml tekočine) skozi zamašek viale.
Transfer all the diluent to the vial.
Celotno vehikel prenesite v vialo.
If the solution is discoloured or contains particles, discard it and start again with a syringe and vial out of your package.
Če je raztopina obarvana ali
90 If foam is present –- which can happen if the vial is shaken or swirled too vigorously – let the vial sit undisturbed until the foam settles.
90 vsebuje delce, jo zavrzite in postopek začnite znova z novim paketom.
D) Drawing up the injection
D) Izvlek količine za injiciranje