natgillin/translations-raw huggingface dataset:
Signs of infection (including TB) such as fever, feeling tired, (persistent) cough, shortness of breath, flu-like symptoms, weight loss, night sweats, diarrhoea, wounds, dental problems or burning when urinating.
znaki okužbe (vključno s TBC), na primer zvišana telesna temperatura, občutek utrujenosti, (trdovraten) kašelj, težko dihanje, gripi podobni simptomi, hujšanje, nočno potenje, driska, rane, težave z zobmi ali pekoč občutek med uriniranjem;
Signs of infection should be monitored and include:
Morali vas bodo tudi spremljati, da ugotovijo morebitne znake okužbe, na primer:
Signs of infection such as fever, feeling sick, wounds, dental problems, burning on urination
znake okužbe, npr. zvišano telesno temperaturo, splošno slabo počutje, rane, težave z zobmi, pekoč občutek med uriniranjem
Signs of infection such as fever, feeling sick, wounds, dental problems, burning on urination;
znake okužbe, npr. zvišano telesno temperaturo, splošno slabo počutje, rane, težave z zobmi, pekoč občutek med uriniranjem;
Signs of infection such as fever, malaise, wounds, dental problems, burning on urination;
znake okužbe, npr. zvišano telesno temperaturo, splošno slabo počutje, rane, težave z zobmi, pekoč občutek med uriniranjem;
Signs of infection.
Znaki okužbe.
Signs of inflammation or infection
znake vnetja ali okužbe
Signs of lactic acidosis include:
Med znaki laktacidoze so:
Signs of lactic acidosis include:
Znaki laktacidoze so:
Signs of liver disorders such as yellow skin and eyes, nausea, loss of appetite, dark-coloured urine and light-coloured stools.
znaki jetrnih bolezni, kot so rumena koža in oči, izguba teka, temno obarvani urin in svetlo obarvano blato.
Signs of liver disorders such as yellow skin and eyes, nausea, loss of appetite, dark-coloured urine and light-coloured stools.
znaki jetrnih bolezni, kot so rumena koža in oči, slabost izguba teka, temno obarvani urin in svetlo obarvano blato.
Signs of liver problems such as yellowing of the skin and /or the eyes (jaundice), whether or not associated with bleeding which appears under the skin as red pinpoint dots and/or confusion (see section 2 ‘Warnings and precautions’).
Znaki jeternih težav, kot je porumenelost kože in/ali oči (zlatenica), ki so lahko, ali pa ne, povezani s krvavitvijo, ki se pojavi pod kožo kot drobne rdeče pike, in/ali zmedenostjo (glejte poglavje 2 »Opozorila in previdnostni ukrepi«).
Signs of local and systemic inflammatory and infectious processes.
znake lokalnih in sistemskih vnetnih in kužnih procesov,
Signs of lung inflammation include:
Med znake vnetja pljuč sodijo:
Signs of nerve disorders, such as numbness or tingling, changes in vision, eye pain, or onset of weakness in an arm or leg
znaki živčnih motenj, npr. omrtvelost ali mravljinčenje, spremembe vida, bolečina v očesu ali pojav šibkosti v roki ali nogi;
Signs of nerve disorders, such as numbness or tingling, changes in vision, eye pain, or onset of weakness in an arm or leg;
znaki živčnih motenj, npr. omrtvelost ali mravljinčenje, spremembe vida, bolečina v očesu ali pojav šibkosti v roki ali nogi;
signs of opiate withdrawal.
kontraceptiva.
signs of opiate withdrawal.
odtegnitve od opiatov.
Signs of oral toxicity in rodents were characteristic of potent neuroleptic compounds: hypoactivity, coma, tremors, clonic convulsions, salivation, and depressed weight gain.
Pri glodavcih so se po peroralnem dajanju pojavili znaki toksičnosti, značilni za močne antipsihotične spojine: hipoaktivnost, koma, tresenje, klonični krči, slinjenje in zmanjšano pridobivanje telesne mase.
Signs of oral toxicity in rodents were characteristic of potent neuroleptic compounds: hypoactivity, coma, tremors, clonic convulsions, salivation, and depressed weight gain.
Znaki toksičnosti po peroralnem dajanju pri glodavcih so bili značilni za močne antipsihotike: hipoaktivnost, koma, tresenje, klonični krči, slinjenje in zmanjšano pridobivanje telesne mase.
Signs of osteonecrosis are joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Znaki osteonekroze so togost sklepa, bolečnost, bolečine (zlasti v kolku, kolenu in rami) in težave z gibljivostjo.
Signs of osteonecrosis are joint stiffness, aches and pains (especially of the hip, knee and shoulder) and difficulty in movement.
Znaki osteonekroze so togost sklepov, srbenje, bolečine (še posebej v kolku, kolenu in rami) in težave pri gibanju.
Signs of PML include:
Znaki PML vključujejo:
Signs of potentially life-threatening skin rashes (Stevens-Johnson syndrome, toxic epidermal necrolysis): initially as reddish target-like spots or circular patches often with central blisters on the trunk.
Znaki morebitno življenje ogrožajočih kožnih izpuščajev (Stevens-Johnsonov sindrom, toksična epidermalna nekroliza): sprva se pojavijo rdečkaste, tarči podobne pike ali krožne lise na trupu, v sredini katerih so pogosto mehurji.
Signs of serious allergic reactions may be rashes that may be itchy or blistering, swelling of the eyes and face, difficulty in breathing or swallowing, a sudden drop in blood pressure and loss of consciousness.
Znaki hude alergijske reakcije so lahko izpuščaji, ki so lahko srbeči ali mehurjasti, oteklina okrog oči in obraza, težave pri dihanju in požiranju, nenaden padec krvnega tlaka in izguba zavesti.
Signs of serious infections
Znaki resnih okužb:
Signs of serious infections, such as high fever that may be accompanied by cough, shortness of breath, chills, weakness, or a hot, red, tender, sore area on the skin or joints
znaki resnih okužb, npr. visoka vročina, ki jo lahko spremljajo kašelj, kratka sapa, mrzlica, šibkost ali vroč, rdeč, občutljiv, boleč predel na koži ali sklepih;
Signs of serious infections, such as high fever that may be accompanied by cough, shortness of breath, chills, weakness, or a hot, red, tender, sore area on the skin or joints;
znaki resnih okužb, npr. visoka vročina, ki jo lahko spremljajo kašelj, kratka sapa, mrzlica, šibkost ali vroč, rdeč, občutljiv, boleč predel na koži ali sklepih;
Signs of severe hypersensitivity reactions (DRESS): initially as flu-like symptoms and a rash on the face then an extended rash with a high temperature (uncommon), increased levels of liver enzymes seen in blood tests (uncommon) an increase in a type of white blood cell (eosinophilia) (rare) and enlarged lymph nodes (uncommon).
Znaki hudih preobčutljivostnih reakcij (DRESS): v začetku se pojavijo gripi podobni simptomi in izpuščaji na obrazu, nato razširjen izpuščaj z visoko telesno temperaturo (občasni), zvišane vrednosti jetrnih encimov, opažene v preiskavah krvi (občasni), povečano število določenega tipa belih krvnih celic (eozinofilija) (redki) ter povečane bezgavke (občasni).
Signs of such reactions include hives, rash, tightness of the chest, wheezing, drop in blood pressure, and breathing difficulties.
Znaki takšnih reakcij so med drugim koprivnica, izpuščaj, stiskanje v prsih, sopenje, padec krvnega tlaka in oteženo dihanje.
Signs of toxicity are deep sedation, ataxia, miosis, convulsions and respiratory depression which is the main symptom.
Znaki zastrupitve so globoka sedacija, ataksija, mioza, krči in depresija dihanja, ki je glavni simptom.
Signs of virilisation, such as voice deepening, hirsutism or clitoromegaly, may be irreversible and discontinuation of treatment should be considered.
Znaki virilizacije, kot so znižan glas, hirsutizem ali klitoromegalija, so lahko ireverzibilni, zato je treba pretehtati možnost prekinitve zdravljenja.
Signs of ‘lactic acidosis’ are:
Znaki laktacidoze so:
Signs of ‘lactic acidosis’ are:
Znaki “laktacidoze” so:
Signs or symptoms of bleeding and when to seek attention from a health care provider.
o znakih in simptomih krvavitve ter o tem, kdaj poiskati zdravniško pomoč
Signs or symptoms of bleeding and when to seek attention from a health care provider.
znake in simptome krvavitve ter kdaj poiskati zdravniško pomoč
Signs or symptoms of bleeding and when to seek attention from a health care provider.
znakih ali simptomih krvavitve ter o tem, kdaj poiskati zdravstveno pomoč
Signs or symptoms of inflammation or infection
znaki ali simptomi vnetja ali okužbe
Signs or symptoms of the safety concern and when to seek attention from a HCP
Znake ali simptome varnostnih tveganj in navodilo, kdaj poiskati zdravniško pomoč.
Signs resolve without treatment within 24 hours.
Vsi ti znaki so prehodni in minejo spontano v 24 urah.
Signs, Symptoms, and Treatment
Znaki, simptomi in zdravljenje
Siklos 100 mg film-coated tablets are off-white, round tablets.
Siklos 100 mg filmsko obložene tablete so sivobele okrogle tablete.
Siklos 100 mg film-coated tablets Siklos 1000 mg film-coated tablets hydroxycarbamide
Siklos 100 mg filmsko obložene tablete Siklos 1000 mg filmsko obložene tablete hidroksikarbamid
Siklos 100 mg film-coated tablets.
Siklos 100 mg filmsko obložene tablete
Siklos 1000 mg film-coated tablets.
Siklos 1000 mg filmsko obložene tablete
Siklos 1000 mg is supplied in plastic bottle of 30 tablets.
Zdravilo Siklos je na voljo v plastenkah, ki vsebujejo 30 tablet.
Siklos is a medicinal product that must be handled with care.
Siklos je zdravilo, s katerim je treba previdno ravnati.
Siklos is a medicine that must be handled with care.
Siklos je zdravilo, s katerim je treba ravnati previdno.
Siklos is indicated for the prevention of recurrent painful vaso-occlusive crises including acute chest syndrome in adults, adolescents and children older than 2 years suffering from symptomatic Sickle Cell Syndrome (see section 5.1).
Zdravilo Siklos je indicirano za preprečevanje ponavljajočih se bolečih vazookluzivnih kriz, vključno z akutnim sindromom bolečine v prsih pri odraslih bolnikih in otrocih, starih več kot 2 leti, ki imajo simptomatični srpasto celični sindrom. (glejte poglavje 5.1)
Siklos is used in adults, adolescents and children over two years of age who have sickle cell syndrome, a genetic disease where the red blood cells become rigid and sticky, and change from being disc- shaped to being crescent-shaped (like a sickle).
Zdravilo Siklos se uporablja pri odraslih, mladostnikih in otrocih, starejših od dveh let, ki imajo srpastocelični sindrom, tj. gensko bolezen, pri kateri rdeče krvne celice postanejo toge in spremenijo obliko iz okroglo-ploščate v srpasto.
Siklos is used to prevent painful crises, including sudden chest pain, caused by Sickle Cell disease, in adults, adolescents and children older than 2 years .
Zdravilo Siklos se uporablja za preprečevanje bolečih kriz, vključno z nenadno bolečino v prsih, ki so posledica srpasto celičnega sindroma, pri odraslih, mladostnikih in otrocih, starejših od 2 let.
Siklos should be used with caution in patients with mild to moderate renal impairment (see section 4.2).
Pri bolnikih z blago ali zmerno ledvično okvaro je treba zdravilo Siklos uporabljati previdno (glejte poglavje 4.2).
Siklos should not be administered to patients with severe renal impairment (creatinine clearance < 30 ml/min) (see sections 4.3, 4.4 and 5.2).
Zdravila Siklos se ne sme dajati bolnikom s hudo ledvično okvaro (očistek kreatinina < 30 ml/min) (glejte poglavja 4.3, 4.4 in 5.2).
Silapo 1 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 1 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 1 000 IU/0.3 ml solution for injection in pre-filled syringe
Silapo 1 000 i.e./0,3 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 1 000 IU/0.3 ml solution for injection in pre-filled syringe Silapo 2 000 IU/0.6 ml solution for injection in pre-filled syringe Silapo 3 000 IU/0.9 ml solution for injection in pre-filled syringe Silapo 4 000 IU/0.4 ml solution for injection in pre-filled syringe Silapo 5 000 IU/0.5 ml solution for injection in pre-filled syringe Silapo 6 000 IU/0.6 ml solution for injection in pre-filled syringe Silapo 8 000 IU/0.8 ml solution for injection in pre-filled syringe Silapo 10 000 IU/1 ml solution for injection in pre-filled syringe Silapo 20 000 IU/0.5 ml solution for injection in pre-filled syringe Silapo 30 000 IU/0.75 ml solution for injection in pre-filled syringe Silapo 40 000 IU/1 ml solution for injection in pre-filled syringe
Silapo 1 000 i.e./0,3 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 2 000 i.e./0,6 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 3 000 i.e./0,9 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 4 000 i.e./0,4 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 5 000 i.e./0,5 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 6 000 i.e./0,6 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 8 000 i.e./0,8 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 10 000 i.e./1 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 20 000 i.e./0,5 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 30 000 i.e./0,75 ml raztopina za injiciranje v napolnjeni injekcijski brizgi Silapo 40 000 i.e./1 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 10 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 10 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 10 000 IU/1 ml solution for injection in pre-filled syringe
Silapo 10 .000 i.e/1 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 10 000 IU/1 ml solution for injection in pre-filled syringe
Silapo 10 000 i.e./1 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 2 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 2 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 2 000 IU/0.6 ml solution for injection in pre-filled syringe
Silapo 2 000 i.e./0,6 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 20 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 20 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 20 000 IU/0.5 ml solution for injection in pre-filled syringe
Silapo 20 000 i.e./0,5 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 3 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 3 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 3 000 IU/0.9 ml solution for injection in pre-filled syringe
Silapo 3 000 i.e./0,9 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 30 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 30 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 30 000 IU/0.75 ml solution for injection in pre-filled syringe
Silapo 30 000 i.e./0,75 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 4 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 4 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 4 000 IU/0.4 ml solution for injection in pre-filled syringe
Silapo 4 000 i.e./0,4 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 40 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 40 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 40 000 IU/1 ml solution for injection in pre-filled syringe
Silapo 40 000 i.e./1 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 40 000 IU/1 ml solution for injection in pre-filled syringe
Silapo 40 000 i.e./1, ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 5 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 5 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 5 000 IU/0.5 ml solution for injection in pre-filled syringe
Silapo 5 000 i.e./0,5 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 6 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 6 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 6 000 IU/0.6 ml solution for injection in pre-filled syringe
Silapo 6 000 i.e./0,6 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo 8 000 IU Injection Epoetin zeta iv/sc use
Silapo injekcija 8 000 i.e. epoetin zeta i.v. ali s.c. uporaba
Silapo 8 000 IU/0.8 ml solution for injection in pre-filled syringe
Silapo 8 000 i.e./0,8 ml raztopina za injiciranje v napolnjeni injekcijski brizgi
Silapo can be injected under the skin by the patient or their carer if they have been trained appropriately.
Bolnik si lahko zdravilo Silapo v podkožje vbrizga sam ali mu ga vbrizga negovalec, če sta bila za to ustrezno usposobljena.
Silapo has no or negligible effect on the ability to drive and use machines.
Zdravilo Silapo nima vpliva ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja s stroji.
Silapo has no or negligible influence on the ability to drive and use machines.
Zdravilo Silapo nima ali ima zanemaljiv vpliv na sposobnost vožnje in upravljanja s stroji.
Silapo is a biosimilar medicinal product.
Zdravilo Silapo je biološko podobno zdravilo.
Silapo is a solution for injection.
Zdravilo Silapo je raztopina za injiciranje.
Silapo is a ‘biosimilar’ medicine.
Zdravilo Silapo je „podobno biološko“ zdravilo.
Silapo is one of a group of products that stimulate the production of red blood cells like the human protein erythropoietin does.
Silapo je eno izmed zdravil, ki spodbuja nastajanje rdečih krvnih celic, podobno kot humana beljakovina eritropoetin.
Silapo is used
Zdravilo Silapo se uporablja
Silapo is used in the following situations:
Zdravilo Silapo se uporablja v naslednjih primerih:
Silapo must not be used in people who are hypersensitive (allergic) to epoetin zeta or any of the other ingredients.
Zdravila Silapo ne smejo uporabljati osebe, ki so preobčutljive za (alergične na) epoetin zeta ali katero koli drugo sestavino zdravila.
Silapo should be administered by the subcutaneous route to patients with anaemia (e.g. haemoglobin concentration ≤ 10 g/dl (6.2 mmol/l).
Bolnikom z anemijo (npr. koncentracije hemoglobina ≤ 10 g/dl (6,2 mmol/l)) je treba zdravilo Silapo dajati subkutano.
Silapo should be administered either subcutaneously or intravenously in order to increase haemoglobin to not greater than 12 g/dL (7.5 mmol/L).
Zdravilo Silapo je treba dajati subkutano ali intravensko, da bi koncentracijo hemoglobina zvečali na vrednost, ki ne presega 12 g/dl (7,5 mmol/l).
Silapo should be administered either subcutaneously or intravenously.
Zdravilo Silapo se lahko daje subkutano ali intravensko
Silapo was also as effective as the reference medicine in patients with kidney problems.
Zdravilo Silapo je bilo pri bolnikih z ledvičnimi težavami enako učinkovito kot referenčno zdravilo.
Silapo was also effective when it was injected under the skin.
Zdravilo Silapo je bilo učinkovito tudi ob injiciranju v podkožje.
Silapo was as effective as Eprex/Erypo in correcting and maintaining red blood cell counts.
Zdravilo Silapo je bilo pri izboljševanju in ohranjanju ravni rdečih krvnih celic enako učinkovito kot zdravilo Eprex/Erypo.
Silapo was studied to show that it is comparable with the reference medicine, Eprex/Erypo, in experimental models and in humans.
Zdravilo Silapo so proučevali s pomočjo poskusnih modelov in preskušanj pri ljudeh, da bi dokazali, da je primerljivo z referenčnim zdravilom Eprex/Erypo.
Silapo, injected into a vein, was compared with the reference medicine in two main studies involving 922 patients who had anaemia associated with chronic renal failure requiring haemodialysis (a technique for removing waste products from the blood).
Zdravilo Silapo, injicirano v veno, so z referenčnim zdravilom primerjali v dveh glavnih študijah, v kateri je bilo vključenih 922 bolnikov z anemijo, ki je bila povezana s kronično ledvično odpovedjo, ki je zahtevala hemodializo (tehniko odstranjevanja odpadnih snovi iz krvi).
Sildenafil
Sildenafil Vardenafil
Sildenafil (100 mg single oral dose) did not affect the steady state pharmacokinetics of the HIV protease inhibitor saquinavir, which is a CYP3A4 substrate/inhibitor.
Sildenafil (v posamičnem peroralnem odmerku 100 mg) ni vplival na farmakokinetiko zaviralca proteaze HIV sakvinavirja (ki je substrat/zaviralec CYP3A4) v stanju dinamičnega ravnovesja.
Sildenafil (50 mg single dose)/ Rilpivirine1
ildenafil (enkratni odmerek 50 mg)/ rilpivirin1
Sildenafil (50 mg single dose)/ Rilpivirine1
ildenafil (enkratni odmerek 50 mg)/rilpivirin1
Sildenafil (or placebo) was added to patients’ background therapy which could have included a combination of anticoagulation, digoxin, calcium channel blockers, diuretics or oxygen.
Sildenafil (ali placebo) so dodali osnovnemu zdravljenju bolnikov, ki je lahko vključevalo kombinacijo antikoagulantov, digoksina, zaviralcev kalcijevih kanalčkov, diuretikov in kisika.
Sildenafil 50 mg single
ildenafil 50 mg
Sildenafil Actavis 100 mg film-coated tablets
Sildenafil Actavis 100 mg filmsko obložene tablete
Sildenafil Actavis 25 mg film-coated tablets
Sildenafil Actavis 25 mg filmsko obložene tablete
Sildenafil Actavis 50 mg film-coated tablets
Sildenafil Actavis 50 mg filmsko obložene tablete
Sildenafil Actavis can be taken with or without food.
Zdravilo Sildenafil Actavis lahko vzamete s hrano ali brez nje.
Sildenafil Actavis can cause dizziness and can affect vision.
Zdravilo Sildenafil Actavis lahko povzroči omotico in lahko neugodno vpliva na vid.
Sildenafil Actavis is a ‘generic medicine’.
Zdravilo Sildenafil Actavis je „generično zdravilo“.
Sildenafil Actavis is not indicated for individuals below 18 years of age.
Zdravilo Sildenafil Actavis ni indicirano pri osebah, mlajših od 18 let.
Sildenafil Actavis is not indicated for use by women.
Zdravilo Sildenafil Actavis ni namenjeno za uporabo pri ženskah.
Sildenafil Actavis will only help you to get an erection if you are sexually stimulated.
Zdravilo Sildenafil Actavis pomaga doseči erekcijo le, če ste spolno stimulirani.
Sildenafil Actavis with food and drink and alcohol
Zdravilo Sildenafil Actavis skupaj s hrano in pijačo
sildenafil AUC ↔ sildenafil Cmin NA sildenafil Cmax ↔ rilpivirine AUC ↔ rilpivirine Cmin ↔ rilpivirine Cmax ↔
sildenafil AUC ↔ sildenafil Cmin NS sildenafil Cmax ↔ rilpivirin AUC ↔ rilpivirin Cmin ↔ rilpivirin Cmax ↔
Sildenafil Cmax ↑ 140 % Sildenafil AUC ↑ 210 %
Cmax sildenafila ↑ 140 % AUC sildenafila ↑ 210
Sildenafil Contraindicated when used for the treatment of pulmonary arterial hypertension (PAH) only.
Sildenafil Kontraindiciran je le, kadar se uporablja za zdravljenje pljučne arterijske hipertenzije (PAH).
Sildenafil Contraindicated when used for the treatment of pulmonary arterial hypertension (PAH) only.
Sildenafil Kontraindiciran je samo v primeru uporabe za zdravljenje pljučne arterijske hipertenzije (PAH).
Sildenafil is a substrate of CYP3A4.
Takrolimus je substrat CYP3A4 in P-glikoproteina.
Sildenafil is a weak inhibitor of the cytochrome P450 isoforms 1A2, 2C9, 2C19, 2D6, 2E1 and 3A4 (IC50 >150 μM).
Sildenafil je šibek zaviralec izoencimov 1A2, 2C9, 2C19, 2D6, 2E1 in 3A4 citokroma P450 (IC50 > 150 µM).
Sildenafil is cleared predominantly by the CYP3A4 (major route) and CYP2C9 (minor route) hepatic microsomal isoenzymes.
Sildenafil v glavnem odstranjujeta jetrna mikrosomska izoencima CYP3A4 (glavna pot) in CYP2C9 (v manjši meri).
Sildenafil metabolism is principally mediated by the cytochrome P450 (CYP) isoforms 3A4 (major route) and 2C9 (minor route).
Metabolizem sildenafila v glavnem poteka z izooblikama 3A4 (glavna pot) in 2C9 (manj pomembna pot) citokroma P450 (CYP).
Sildenafil ratiopharm 100 mg film-coated tablets EU/1/09/603/009
Sildenafil ratiopharm 100 mg filmsko obložene tablete
Sildenafil ratiopharm 100 mg film-coated tablets Sildenafil
Sildenafil ratiopharm 100 mg filmsko obložene tablete sildenafil
Sildenafil ratiopharm 25 mg film-coated tablets
Sildenafil ratiopharm 25 mg filmsko obložene tablete
Sildenafil ratiopharm 25 mg film-coated tablets Sildenafil
Sildenafil ratiopharm 25 mg filmsko obložene tablete sildenafil
Sildenafil ratiopharm 25 mg film-coated tablets Sildenafil ratiopharm 50 mg film-coated tablets Sildenafil ratiopharm 100 mg film-coated tablets
Sildenafil ratiopharm 25 mg filmsko obložene tablete Sildenafil ratiopharm 50 mg filmsko obložene tablete Sildenafil ratiopharm 100 mg filmsko obložene tablete
Sildenafil ratiopharm 50 mg film-coated tablets EU/1/09/603/005
Sildenafil ratiopharm 50 mg filmsko obložene tablete
Sildenafil ratiopharm 50 mg film-coated tablets Sildenafil
Sildenafil ratiopharm 50 mg filmsko obložene tablete sildenafil
Sildenafil ratiopharm are white to off-white, oblong film-coated tablets with edge and score line on one side.
Sildenafil ratiopharm so bele do belkaste, podolgovate, filmsko obložene tablete z robom in razdelilno zarezo na eni strani.