natgillin/translations-raw huggingface dataset:
Severe allergic reactions (anaphylactic reaction) – you may experience localised itching and swelling of the hands, feet, ankles, face. lips, mouth, tongue or throat
hude alergijske reakcije (anafilaktična reakcija) – pojavi se lahko lokalno srbenje in oteklost rok, nog, gležnjev, obraza, ustnic, ust, jezika ali grla
Severe allergic reactions (e.g. anaphylaxis), an immune system disorder called lupus, allergic reactions to foreign proteins
hude alergijske reakcije (npr. anafilaksija), motnja v delovanju imunskega sistema (lupus), alergijske reakcije na tuje beljakovine
Severe allergic reactions (e.g. anaphylaxis), an immune system disorder called lupus, allergic reactions to foreign proteins
hude alergijske reakcije (npr. anafilaksija), motnja v delovanju imunskega sistema (lupus), alergijske reakcije na tuje beljakovine,
Severe allergic reactions (rare, may affect up to 1 in 1,000 people) – the signs may include large-scale skin reactions (rash and itching all over the body), severe swelling of skin or mucous membranes (angiooedema), shortness of breath, a fall in blood pressure with rapid heart beat and sweating.
Huda alergijska reakcija (redka, pojavi se lahko pri največ 1 od 1.000 bolnikov) – znaki so lahko obsežne kožne reakcije (izpuščaj in srbenje po celem telesu), hude otekline kože ali sluznic (angioedem), oteženo dihanje, znižanje krvnega tlaka s hitrim bitjem srca in znojenje.
Severe allergic reactions (rare, may affect up to 1 in 1,000 people).The signs may include rash and itching all over the body, swelling of skin or mouth, shortness of breath, feeling faint (a fall in blood pressure) with fast heart beat and sweating.
Hude alergijske reakcije (redke, pojavijo se lahko pri največ 1 od 1.000 oseb) – med znaki so lahko izpuščaj in srbenje po vsem telesu, oteklost kože ali ust, kratka sapa, omedlevica (padec krvnega tlaka) s hitrim bitjem srca in znojenjem.
severe allergic reactions (see the beginning of section 4)
hude alergijske reakcije (glejte začetek poglavja 4).
Severe allergic reactions have not been seen in clinical studies so far, however it is not yet possible to say for certain that a severe allergic reaction will not happen when you are given Prialt.
V kliničnih študijah zaenkrat niso opažali resnih alergijskih reakcij, vendar pa ni moč z gotovostjo trditi, da ne bo prišlo do resne alergijske reakcije, ko boste prejeli zdravilo Prialt.
Severe allergic reactions including dizziness and difficulty breathing, swelling mainly of the face and throat, decreased blood pressure, dehydration secondary to post-dose symptoms such as fever, vomiting and diarrhoea.
Hude alergijske reakcije, vključno z omotičnostjo in oteženim dihanjem, otekanje predvsem v obraz in grlo oziroma žrelo, znižan krvni tlak, dehidracija zaradi simptomov po odmerjanju, kot so zvišana telesna temperatura, bruhanje in diareja.
Severe allergic reactions to insulin may occur which may become life-threatening.
Pojavi se lahko huda alergijska reakcija na insulin, ki lahko postane smrtno nevarna.
Severe allergic reactions to insulins
Hude alergijske reakcije na insuline
Severe allergic reactions to insulins may become life-threatening.
Huda alergijske reakcija na insuline lahko postane smrtno nevarna.
Severe allergic reactions with swelling and difficulty breathing which could be life-threatening
hude alergijske reakcije z otekanjem in težavami pri dihanju, ki lahko ogrožajo življenje,
Severe allergic reactions with swelling and difficulty breathing, which could be life- threatening
hude alergijske reakcije z otekanjem in težavami pri dihanju, ki lahko ogrožajo življenje,
Severe allergic rhinitis
hud alergijski rinitis,
Severe allergic-type hypersensitivity reactions are possible, including urticaria, difficulty breathing and/or cardiovascular collapse.
Možne so resne preobčutljivostne reakcije alergijske vrste, vključno z urtikarijo, težavami z dihanjem in/ali kardiovaskularni kolaps.
Severe anaemia
huda anemija
Severe anaphylactic and other hypersensitivity reactions
hude anafilaktične in druge preobčutljivostne reakcije
Severe and life-threatening hepatotoxicity, including fatal fulminant hepatitis, has occurred in patients treated with nevirapine.
Pri z nevirapinom zdravljenih bolnikih so se pojavili hudi in življenjsko nevarni toksični jetrni učinki, tudi fulminantni hepatitis s smrtnim izidom.
Severe and life-threatening skin reactions and allergic reactions have been reported in some patients taking raltegravir (one of the medicines in DUTREBIS).
Pri nekaterih bolnikih, ki so prejemali raltegravir (eno od zdravilnih učinkovin v zdravilu DUTREBIS), so bile opisane hude in življenjsko nevarne kožne in alergijske reakcije.
Severe and life-threatening skin reactions have occurred in patients treated with nevirapine, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).
Pri bolnikih, ki so se zdravili nevirapinom, so se pojavile hude in življenjsko nevarne kožne reakcije, tudi Stevens-Johnsonov sindrom in toksična epidermalna nekroliza.
Severe and life-threatening skin reactions, including fatal cases, have occurred in patients treated with nevirapinemainly during the first 6 weeks of therapy.
Pri z nevirapinom zdravljenih bolnikih so se (pretežno prvih 6 tednov zdravljenja) pojavile hude in življenjsko nevarne kožne reakcije, tudi s smrtnim izidom.
Severe and persistent pain in the abdomen (stomach area) which might reach through to your back as well as nausea and vomiting, as it could be a sign of an inflamed pancreas (pancreatitis).
Huda in trdovratna bolečina v trebuhu (v predelu želodca), ki lahko izžareva v hrbet, pa tudi siljenje na bruhanje in bruhanje, so lahko znak vnetja trebušne slinavke (pankreatitisa).
Severe and persistent pain in the abdomen (stomach area) which might reach through to your back, as well as nausea and vomiting, as it could be a sign of an inflamed pancreas (pancreatitis).
Huda in trdovratna bolečina v trebuhu (v predelu želodca), ki lahko izžareva v hrbet, pa tudi siljenje na bruhanje in bruhanje, so lahko znak vnetja trebušne slinavke (pankreatitisa).
Severe and/or Life-
Hudi in/ali
Severe and/or Life-
Resni in/ali
Severe and/or Life- threatening (grade 3-4) or considered medically relevant
Hudi in/ali življenjsko ogrožajoči (stopnja 3-4) ali klinično pomembni
Severe and/or Life- threatening (grade 3-4) or considered medically relevant
Hudi in/ali življenjsko ogrožajoči (stopnja 3–4) ali klinično pomembni
Severe arrhythmias.
hude aritmije
Severe arrhythmias.
Hude aritmije.
Severe arterial thromboembolic events (see section 4.4).
Resni arterijski trombembolični dogodki (glejte poglavje 4.4).
Severe asthma exacerbations
Težke eksacerbacije astme
Severe bleeding is uncommon, but can be life threatening.
Hude krvavitve so občasne, vendar so lahko smrtno nevarne.
Severe bleeding or bruising;
hude krvavitve ali podplutbe,
Severe bleeding reactions have been reported in non-MS patients.
Pri bolnikih, ki niso imeli MS, so poročali o hudih reakcijah s krvavitvijo.
Severe blood coagulation disorders,
hude motnje strjevanja krvi,
Severe blood infection (sepsis) accompanied by fever, chills and severe shaking, and possibly complicated by low blood pressure and confusion (septic shock).
huda okužba krvi (sepsa), ki jo spremljajo povišana telesna temperatura, mrzlica in hudo tresenje, z možnim zapletom zaradi nizkega krvnega tlaka in zmedenostjo (septični šok),
Severe bone marrow suppression (severe leukopaenia, neutropaenia, or thrombocytopaenia; see section 4.2, Table 5).
Huda supresija kostnega mozga (huda levkopenija, nevtropenija ali trombocitopenija; glejte poglavje 4.2, Preglednico 5).
Severe bone, joint and/or muscle pain, occasionally incapacitating.
Hude bolečine v kosteh, sklepih in/ali mišicah, ki bolnika v nekaterih primerih onemogočijo.
Severe breathing problems
resne težave z dihanjem,
Severe cardiac disease
Huda bolezen srca
Severe cardiovascular disease
Parkinsonova bolezen
Severe cases of diarrhoea may require administration of oral or intravenous electrolytes and fluids, use of antibiotics such as fluoroquinolones (especially if diarrhoea is persistent beyond 24 hours, there is fever, or grade 3 or 4 neutropenia) and interruption or discontinuation of Tyverb therapy (see section 4.2 – dose delay and dose reduction –diarrhoea).
V hudih primerih driske bo morda potrebno peroralno ali intravensko dajanje elektrolitov in tekočin, uporaba antibiotikov, npr. fluorokinolonov (zlasti če driska traja več kot 24 ur, če ima bolnik zvišano telesno temperaturo ali nevtropenijo stopnje 3 ali 4), ter prekinitev ali ukinitev zdravljenja z zdravilom Tyverb (glejte poglavje 4.2 – Odložitev zdravljenja in zmanjšanje odmerka – Driska).
Severe cases of haemorrhagic events, including central nervous system haemorrhage, have been reported in clinical studies; these events were independent of ethnicity.
V kliničnih študijah so bili opisani primeri hudih krvavitev, vključno s krvavitvami v osrednje živčevje; ti učinki niso bili odvisni od rase.
Severe cases, sometimes with fatal outcome, were associated with pancreatitis, liver failure/hepatic steatosis, renal failure and higher levels of serum lactate.
Hudi primeri, nekateri s smrtnim izidom, so bili povezani s pankreatitisom, odpovedjo/steatozo jeter, odpovedjo ledvic in zvišanimi koncentracijami laktata v serumu.
Severe cases, sometimes with fatal outcome, were associated with pancreatitis, liver failure/hepatic steatosis, renal failure and higher levels of serum lactate.
Hudi primeri, včasih s smrtnim izidom, so bili povezani s pankreatitisom, odpovedjo jeter/steatozo jeter, odpovedjo ledvic in visoko koncentracijo laktata v serumu.
Severe central anticholinergic effects (e.g. hallucinations, severe excitation): treat with physostigmine
hude osrednje antiholinergične učinke (npr. halucinacije, hudo eksitacijo) s fizostigminom;
Severe chest pain due to angina
huda bolečina v prsih zaradi angine pektoris
Severe chest pains, irregular heart beat, feeling faint and heart attack
hude bolečine v prsih, nepravilen srčni ritem, občutek omedlevanja in srčni napad
Severe circulatory shock.
Resen cirkulatorni šok
Severe CNS effects, particularly depression, suicidal ideation and attempted suicide have been observed in some patients during IntronA therapy, and even after treatment discontinuation mainly during the 6-month follow-up period.
Med terapijo z zdravilom IntronA in celo po ukinitvi zdravljenja, predvsem v 6-mesečnem obdobju spremljanja, so pri nekaterih bolnikih opažali hude učinke na CŽS, še posebej depresijo, samomorilne misli in poskus samomora.
Severe CNS effects, particularly depression, suicidal ideation and attempted suicide have been observed in some patients during Ribavirin Teva Pharma B.V. combination therapy with peginterferon alfa-2b or interferon alfa-2b, and even after treatment discontinuation mainly during the 6-month follow-up period.
Pri nekaterih bolnikih so med kombinirano terapijo z zdravilom Ribavirin Teva Pharma B.V. in peginterferonom alfa-2b ali interferonom alfa-2b opažali hude učinke na CŽS, še posebej depresijo, samomorilne misli in tudi poskus samomora, celo po ukinitvi zdravljenja, predvsem v 6-mesečnem obdobju spremljanja.
Severe condition of the skin that causes red, often itchy spots, similar to the rash of measles, which starts on the limbs and sometimes on the face and the rest of the body (erythema multiforme), skin disease with thickened patches of red skin, often with silvery scales (psoriasis), skin condition of the face where the nose and cheeks are unusually red (rosacea), hives (itchy, bumpy rash)
resno kožno stanje, pri katerem se na koži pojavijo rdeči, pogosto srbeči madeži, podobni izpuščaju pri ošpicah, ki se začnejo na okončinah, včasih pa tudi na obrazu in ostalih delih telesa (multiformni eritem), bolezen kože z zadebeljenimi predeli pordele kože, ki so pogosto prekriti s srebrnimi luskami (luskavica), bolezen kože obraza, pri kateri so nos in lica neobičajno rdeči (rozacea), koprivnica (srbeč, izbokel izpuščaj)
Severe confusion
Huda zmedenost
Severe confusion
huda zmedenost,
Severe coronary heart disease or unstable angina.
huda koronarna srčna bolezen ali nestabilna angina pektoris
Severe coronary heart disease or unstable angina.
Huda koronarna srčna bolezen ali nestabilna angina.
Severe cough.
Hud kašelj.
Severe cutaneous adverse reactions
Hude koţne neţelene reakcije
Severe cutaneous adverse reactions (SCARs) including Stevens Johnson syndrome, toxic epidermal necrolysis (TEN) and oral mucosal reactions, rash, pruritus, urticaria
hude kožne neželene reakcije (angl. severe cutaneous adverse reactions (SCAR)), vključno s Stevens-Johnsovim sindromom, s toksično epidermalno nekrolizo (toxic epidermal necrolysis-TEN), z reakcijami ustne sluznice, izpuščajem, srbenjem, urtikarijo
Severe cutaneous adverse reactions (SCARs) including Stevens Johnson syndrome, toxic epidermal necrolysis (TEN) and oral mucosal reactions, rash, pruritus, urticaria
hude kožne neželene reakcije (severe cutaneous adverse reactions- SCAR), vključno s Stevens-Johnsovim sindromom, s toksično epidermalno nekrolizo (toxic epidermal necrolysis-TEN) in z reakcijami ustne sluznice, izpuščaj, srbenje, urtikarija
Severe cutaneous adverse reactions (SCARs) including Stevens Johnson syndrome, toxic epidermal necrolysis (TEN), oral mucosal reactions, rash, pruritus, urticaria
hude kožne neželene reakcije (angl. severe cutaneous adverse reactions SCAR), vključno s Stevens-Johnsovim sindromom, s toksično epidermalno nekrolizo (toxic epidermal necrolysis-TEN), z reakcijami ustne sluznice, izpuščajem, srbenjem, urtikarijo
Severe cutaneous adverse reactions (SCARs) including Stevens Johnson syndromea, toxic epidermal necrolysis (TEN)a, oral mucosal reactionsa, pruritusa
hude kožne neželene reakcije (angl. severe cutaneous adverse reactions - SCAR), vključno s Stevens-Johnsovim sindromoma, toksična epidermalna nekroliza (toxic epidermal necrolysis - TEN)a, reakcije ustne sluznicea, srbenjea
Severe cutaneous adverse reactions (SCARs) including Stevens Johnson syndromea, toxic epidermal necrolysis (TEN)a, oral mucosal reactionsa, rasha,am, pruritusa,am, urticariaa,am, alopeciaam, purpuraam, skin decolourationam, hyperhidrosisam, exanthemaam
hude kožne neželene reakcije (angl. severe cutaneous adverse reactions-SCAR), vključno s Stevens-Johnsovim sindromoma, toksično epidermalno nekrolizo (angl. toxic epidermal necrolysis-TEN)a, reakcije ustne sluznicea, izpuščaja,am, srbenjea,am, urtikarijaa,am, alopecjiaam, purpuraam, razbarvanje kožeam, čezmerno znojenjeam, eksantemam
Severe cutaneous adverse reactions (SCARs): Stevens-Johnson syndrome and toxic epidermal necrolysis* (see section 4.4)#
hude neželene kožne reakcije (SCARs – severe cutaneous adverse reactions): Stevens-Johnsonov sindrom in toksična epidermalna nekroliza* (glejte poglavje 4.4)#
Severe cutaneous adverse reactions (SCARs): Stevens-Johnson syndrome and toxic epidermal necrolysis* (see section 4.4)#
hude neželene kožne reakcije (SCARs –severe cutaneous adverse reactions): Stevens- Johnsonov sindrom in toksična epidermalna nekroliza* (glejte poglavje 4.4)#
Severe cutaneous adverse reactions, such as Stevens-Johnson syndrome, have been reported during treatment with azole antifungal agents.
Pri zdravljenju z azolskimi antimikotiki so poročali o hudih koţnih neţelenih reakcijah, kot je Stevens-Johnsonov sindrom.
Severe cutaneous reactions (e.g erythema multiforme, Ste vens-Johnson syndrome, toxic epidermal necrolysis, etc.)
hude reakcije na koži (npr. multiformni eritem, Stevens-Johnsonov sindrom, toksična epidermalna nekroliza, itd.)
Severe cutaneous reactions have been reported, including cases of erythema multiforme (EM) and cases suggestive of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), some of which were fatal.
Poročali so o hudih kožnih reakcijah, vključno s primeri multiformnega eritema (EM) ter primeri, ki so nakazovali Stevens-Johnsonov sindrom (SJS) in toksično epidermalno nekrolizo (TEN), od katerih jih je bilo nekaj smrtnih.
Severe cytokine release syndrome is characterised by severe dyspnea, often accompanied by bronchospasm and hypoxia, in addition to fever, chills, rigors, urticaria, and angioedema.
Za hud sindrom sproščanja citokinov je značilna huda dispneja, ki jo pogosto spremljata bronhospazem in hipoksija, poleg zvišane telesne temperature, mrzlice, drgetanja, urtikarije in angioedema.
Severe decrease in a specific class of white blood cells (agranulocytosis)
hudo zmanjšanje v specifični skupini belih krvnih celic (agranulocitoza)
Severe dermatologic reactions have been reported in patients receiving vemurafenib, including rare cases of Stevens-Johnson syndrome and toxic epidermal necrolysis in the pivotal clinical trial.
Pri bolnikih, ki so prejemali vemurafenib, so v ključnem kliničnem preskušanju poročali o hudih kožnih reakcijah, vključno z redkim Stevens-Johnsonovim sindromom in toksično epidermalno nekrolizo.
Severe diarrhoea
Huda driska
Severe diarrhoea
hudo drisko
Severe diarrhoea (NCI-CTC grade 3 and 4) was reported in 2% of patients treated with Vectibix as a monotherapy and in 17% of patients treated with Vectibix in combination with chemotherapy.
O hudi (3. in 4. stopnja po NCI-CTC) driski so poročali pri 2 % bolnikov, zdravljenih z zdravilom Vectibix v monoterapiji, in pri 17 % bolnikov, zdravljenjih z zdravilom Vectibix v kombinaciji s kemoterapijo.
Severe diarrhoea or colitis has been observed with nivolumab monotherapy or nivolumab in combination with ipilimumab (see section 4.8).
Pri zdravljenju z nivolumabom v monoterapiji ali zdravljenju z nivolumabom v kombinaciji z ipilimumabom so poročali o hudi driski ali kolitisu (glejte poglavje 4.8).
Severe diarrhoea, nausea or vomiting
huda driska, slabost ali bruhanje,
Severe disabilities such as deafness and loss of vision may also occur.
Prav tako lahko pride do resne prizadetosti, kot sta naglušnost in okvara vida.
Severe dyspnoea at rest due to complications of advanced malignancy or requiring supplementary oxygen therapy.
Pri bolnikih, ki imajo hudo dispnejo v mirovanju zaradi komplikacij napredovale maligne bolezni, ali pri tistih, ki potrebujejo zdravljenje s kisikom.
Severe effects may occur, including allergic and anaphylactic reactions (a very serious type of allergic reaction with fainting and difficulty breathing, which needs immediate medical attention).
Pojavijo se lahko resni neželeni učinki, vključno z alergijskimi in anafilaktičnimi reakcijami (zelo huda alergijska reakcija z omedlevanjem in težkim dihanjem, ki zahteva takojšnjo zdravniško pomoč).
Severe endocrinopathies, including hypophysitis, type 1 diabetes mellitus, diabetic ketoacidosis, hypothyroidism, and hyperthyroidism have been observed with pembrolizumab treatment.
Med zdravljenjem s pembrolizumabom so poročali o hudih endokrinopatijah, vključno s hipofizitisom, sladkorno boleznijo tipa 1, diabetično ketoacidozo, hipotiroidizmom in hipertiroidizmom.
Severe endocrinopathies, including hypothyroidism, hyperthyroidism, adrenal insufficiency, hypophysitis, diabetes mellitus, and diabetic ketoacidosis have been observed with nivolumab monotherapy or nivolumab in combination with ipilimumab (see section 4.8).
Pri zdravljenju z nivolumabom v monoterapiji ali zdravljenju z nivolumabom v kombinaciji z ipilimumabom so poročali o hudih endokrinopatijah, vključno s hipotiroidizmom, hipertiroidizmom, insuficienco nadledvičnih žlez, vnetjem hipofize, diabetesom in diabetično ketoacidozo (glejte poglavje 4.8).
Severe endocrinopathies, including hypothyroidism, hyperthyroidism, adrenal insufficiency, hypophysitis, diabetes mellitus, and diabetic ketoacidosis have been observed with nivolumab treatment.
Pri zdravljenju z nivolumabom so poročali o hudih endokrinopatijah, vključno s hipotiroidizmom, hipertiroidizmom, insuficienco nadledvičnih žlez, vnetjem hipofize, sladkorno boleznijo in diabetično ketoacidozo.
Severe exacerbationsa
Huda poslabšanjaa Dogod Dogodki/boln ki ik-leto
Severe eye disorders
Hude očesne bolezni.
Severe FH (N = 102)
Huda DH (N = 102)
Severe flares over 52 weeks
Huda poslabšanja v 52 tednih
Severe flares were observed in 15.6% of the Benlysta group compared to 23.7% of the placebo group over the 52 weeks of observation (observed treatment difference = - 8.1%; hazard ratio=0.64, p=0.0011).
Huda poslabšanja so med 52 tedni opazovanja ugotovili pri 15,6 % skupine, ki je prejemala zdravilo Benlysta, in pri 23,7 % skupine, ki je prejemala placebo (opažena terapevtska razlika = -8,1 %, razmerje tveganj = 0,64, p = 0,0011).
Severe forms of fluid retention such as pleural effusion, pulmonary oedema, and pericardial effusion were uncommonly (0.1 to 1%) observed in a Phase III study of newly diagnosed CML patients.
V študiji faze III pri bolnikih z novo odkrito KML so občasno (0,1 do 1 %) opažali hude oblike zastajanja tekočine kot so plevralni izliv, pljučni edem in perikardialni izliv.
Severe gastrointestinal disorders such as chronic or severe constipation, intestinal stenosis, intestinal diverticulum, sigmoid colitis, gastrointestinal ulcers, or recent major gastrointestinal surgery
hudimi gastrointestinalnimi motnjami, kot so kronično ali hudo zaprtje, stenoza črevesja, divertikel črevesja, sigmoidni kolitis, gastrointestinalne razjede ali nedavna velika gastrointestinalna operacija,
Severe growth depression, ataxia, paralysis or death may result.
Pojavi se lahko hudo zaviranje rasti, ataksija, paraliza ali smrt.
Severe haemolysis seems to be slightly more frequent with Privigen than with some other products containing the same active substance.
V primerjavi z nekaterimi drugimi zdravili, ki vsebujejo enako zdravilno učinkovino, je pojav hujše oblike hemolize pri jemanju zdravila Privigen malo pogostejši.
Severe haemorrhage
hude krvavitve
Severe haemorrhage has been observed with cabozantinib.
Pri uporabi kabozantiniba so opazili hude krvavitve.
Severe haemorrhagic events are more frequent in patients ≥ 75 years of age (including fatal events) or those weighing < 60 kg
Hude krvavitve so pogostejše pri bolnikih starih ≥ 75 let (vključno s smrtnimi primeri) ali s telesno maso < 60 kg.
Severe headache often accompanied by nausea, vomiting and sensitivity to light (migraine)
hud glavobol, običajno s slabostjo, bruhanjem in preobčutljivostjo za svetlobo (migrena),
Severe headache, weakness or paralysis of limbs or face, difficulty speaking, sudden loss of consciousness (signs of nervous system problems such as bleeding or swelling in skull/brain).
hud glavobol, oslabelost ali ohromelost okončin ali obraza, težave pri govoru, nenadna izguba zavesti (znaki težav z živčevjem kot sta krvavitev ali otekanje v lobanjski votlini/možganih),
Severe headache, weakness or paralysis of limbs or face, difficulty speaking, sudden loss of consciousness (signs of nervous system problems such as bleeding or swelling in skull/brain).
hud glavobol, oslabelost ali ohromelost okončin ali obraza, težave pri govoru, nenadna izguba zavesti (znaki težav z živčevjem, kot sta krvavitev ali otekanje v lobanjski votlini/možganih),
Severe heart or blood vessels disease.
Huda srčna ali žilna bolezen.
Severe hepatic dysfunction (serum albumin <25 g/l or Child-Pugh score >10) (Class C).
Hudo poslabšano delovanje jeter (albumin v serumu < 25 g/l ali ocena po Child-Pughu > 10) (stopnja C)
Severe hepatic dysfunction or decompensated cirrhosis of the liver
huda motnja jetrnega delovanja ali dekompenzirana ciroza jeter,
Severe hepatic dysfunction or decompensated cirrhosis of the liver;
huda jetrna okvara ali dekompenzirana jetrna ciroza,
Severe hepatic dysfunction, including hepatic failure, cirrhosis, portal hypertension (oesophageal varices) and active hepatitis
hude motnje delovanja jeter, kot so jetrna odpoved, ciroza, portalna hipertenzija (varice v požiralniku) in aktivni hepatitis,
Severe hepatic function disorder.
Hudo moteno delovanje jeter.
Severe hepatic impairment
Huda jetrna okvara.
Severe hepatic impairment
Huda okvara jeter.
Severe hepatic impairment (Child-Pugh Classification B or C) or decompensated cirrhosis of the liver.
Huda jetrna okvara (z oceno po Child-Pugh B ali C) ali dekompenzirana jetrna ciroza;