natgillin/translations-raw huggingface dataset:
However, it is not possible to definitively determine whether these events are related directly to these risk factors, to tadalafil, to sexual activity, or to a combination of these or other factors.
Vendar pa ni mogoče dokončno potrditi, ali so omenjeni dogodki neposredno povezani s temi dejavniki tveganja, z zdravilom Tadalafil Mylan, s spolno aktivnostjo ali s kombinacijo naštetih ali drugih dejavnikov.
However, it is possible that if you experience any of the side effects listed in section 4, then some of these may affect your ability to drive or use machines (e.g. dizziness).
Vendar pa se lahko pojavijo nekateri neželeni učinki, našteti v poglavju 4, ki lahko vplivajo na sposobnost vožnje in upravljanja s stroji (npr. omotica).
However, it is preferable that Victoza is injected around the same time of the day, when the most convenient time of the day has been chosen.
Vendar je priporočljivo zdravilo Victoza injicirati vsak dan ob istem času, ko je to najprimerneje.
However, it is recommended that MabCampath should not be given within 3 weeks of other chemotherapeutic agents.
Vendar zdravila naj ne bi uporabljali prej kot 3 tedne pred oz. po drugih kemoterapevtikih.
However, it is theoretically possible that a breast-fed baby could experience serious side effects to Betaferon.
Vendar so pri dojenčkih teoretično možne resne neželene reakcije na zdravilo Betaferon.
However, it is theoretically possible that a breast-fed baby could experience serious side effects to Extavia.
Vendar so pri dojenčkih teoretično možne resne neželene reakcije na zdravilo Extavia.
However, it is to be noted that the exposure to 5-FU can be variable and unexpectedly higher in patients with severe renal impairment due to the impact of fluctuations in renal function in these patients.
Treba pa je poudariti, da lahko pri bolnikih s hudo ledvično okvaro izpostavljenost 5-FU niha in je lahko nepričakovano večja zaradi vpliva nihanja ledvičnega delovanja pri teh bolnikih.
However, it is unknown whether the combination of tipranavir with ritonavir might cause a larger
Ni pa znano, ali bi lahko kombinacija tipranavirja in ritonavirja še močneje povečala izpostavljenost trazodonu.
However, it may not be completely excluded that rilpivirine can increase the exposure to other medicinal products transported by P-glycoprotein that are more sensitive to intestinal P-glycoprotein inhibition (e.g. dabigatran etexilate).
Vendar pa ni mogoče povsem izključiti, da lahko rilpivirin zviša izpostavljenost drugim zdravilom, ki jih prenaša P-glikoprotein in so bolj občutljiva na zaviranje črevesnega P-glikoproteina (npr. dabigatran eteksilat).
However, it may not be completely excluded that rilpivirine can increase the exposure to other medicines transported by P-glycoprotein that are more sensitive to intestinal P-gp inhibition, e.g. dabigatran etexilate.
Kljub temu ne moremo povsem izključiti možnosti, da rilpivirin lahko poveča izpostavljenost drugim učinkovinam, ki jih prenaša P-glikoprotein in so bolj občutljive na zaviranje črevesnega P-gp, npr. dabigatran eteksilat.
However, it must be borne in mind that sex steroids can promote the growth of certain hormone- dependent tissues and tumours.
Treba pa je upoštevati, da lahko spolni steroidni hormoni spodbujajo rast določenih hormonsko odvisnih tkiv in tumorjev.
However, it should be noted that systemic exposure in rodents was similar or even lower than therapeutic exposure in humans at the 125 mg/80 mg and 165 mg doses.
Vendar je treba opozoriti, da je bila sistemska izpostavljenost pri glodalcih podobna ali celo manjša od terapevtske izpostavljenosti pri človeku pri odmerkih 125 mg/80 mg in 165 mg.
However, it should be noted that systemic exposure in rodents was similar or even lower than therapeutic exposure in humans at the 125 mg/80 mg dose.
Vendar je treba opozoriti, da je bila sistemska izpostavljenost pri glodalcih podobna ali celo manjša od terapevtske izpostavljenosti pri človeku pri odmerku 125 mg/80 mg.
However, it should be noted that the incidence of somnolence is increased at doses higher than 1.5 mg/day (see section 4.8).
Pri tem je treba upoštevati, da je zaspanost pogostejša pri dnevnih odmerkih, ki so večji od 1,5 mg (glejte poglavje 4.8).
However, it should be noted that the value of the toxicity studies carried out with rodents, rabbit and monkey, including the reproduction toxicity studies, are limited since systemic exposures to fosaprepitant and aprepitant were only similar or even lower than therapeutic exposure in humans.
Vendar pa je treba izpostaviti, da je vrednost študij toksičnosti, izvedenih na glodavcih, kuncih in opicah, vključno s študijami vplivov na sposobnost razmnoževanja, omejena, saj je bila sistemska izpostavljenost fosaprepitantu in aprepitantu le podobna ali celo manjša od sistemske izpostavljenosti človeka pri uporabi terapevtskih odmerkov.
However, it should be noted that there are no clinical efficacy data to support administration by the subcutaneous route.
Vendar morate upoštevati, da ni podatkov o klinični učinkovitosti subkutane uporabe.
However, it was negative in an in vivo mouse bone marrow micronucleus assay.
Pri testu mikrojeder mišjega kostnega mozga in vivo pa je bil rezultat negativen.
However, it withdrew this application during the initial assessment of the medicine.
Vendar pa je družba to vlogo med prvotnim vrednotenjem zdravila umaknila.
However, keep taking Myclausen until you see him or her.
Vendar pa do obiska zdravnika nadaljujte z jemanjem zdravila Myclausen.
However, keep taking Mycophenolate mofetil Teva until you see him or her.
Vendar pa do obiska zdravnika nadaljujte z jemanjem zdravila Mofetilmikofenolat Teva.
However, lactating mothers should be advised to avoid breast feeding or alternative medicinal products used.
Vendar je treba doječim materam svetovati, naj ne dojijo ali naj uporabljajo druga zdravila.
However, lactic acidosis, sometimes fatal, has been reported in pregnant women who received the combination of didanosine and stavudine with or without other anti-retroviral treatment (see sections
Vendar je bila pri nosečnicah, ki so dobivale kombinacijo didanozina in stavudina – z drugimi protiretrovirusnimi zdravili ali brez njih – opisana laktacidoza, ki je bila včasih usodna (glejte poglavji
However, limited clinical data with another P-gp substrate (everolimus) suggest that the inhibition of P-gp with tacrolimus is weaker than that observed with strong P-gp inhibitors.
Toda manjše število kliničnih podatkov za drugi substrat P-gp (everolimus) kaže, da je zaviralni učinek na P-gp pri takrolimusu šibkejši kot pri močnih zaviralcih P-gp.
However, limited data are available on the efficacy and safety of emtricitabine (as a 200 mg hard capsule once daily) in patients who are co-infected with HIV and HBV.
Vendar pa so na voljo omejeni podatki o učinkovitosti in varnosti uporabe emtricitabina (v obliki 200 mg trde kapsule enkrat dnevno) pri bolnikih s hkratno okužbo z HIV in HBV.
However, long term use of acetylsalicylic acid is not recommended for the management of flushing.
Vendar pa se dolgotrajna uporaba acetilsalicilne kisline ne priporoča za zdravljenje vročinskega oblivanja.
However, long-term safety data for the emtricitabine and tenofovir disoproxil fumarate components of Eviplera have not been evaluated in patients with mild renal impairment.
Vendar pa dolgoročni podatki o varnosti sestavin zdravila Eviplera emtricitabina in dizoproksiltenofovirijevega fumarata, pri bolnikih z blago ledvično okvaro niso bili ovrednoteni.
However, long-term safety data for the emtricitabine and tenofovir disoproxil fumarate components of Eviplera have not been evaluated in patients with mild renal impairment.
Vendar pa dolgoročni podatki o varnosti sestavin zdravila Eviplera, emtricitabina in dizoproksiltenofovirijevega fumarata, pri bolnikih z blago ledvično okvaro niso bili ovrednoteni.
However, maternal exposure levels were considerably lower than those maximally reported in clinical setting (10–500 times lower than human AUC, 3–50 times lower than the human Cmax).
Vendar pa so bile ravni izpostavljenosti matere znatno nižje od najvišjih, poročanih v kliničnem okolju (10–500- krat nižje kot AUC pri človeku, 3–50-krat nižje kot Cmax pri človeku).
However, mepolizumab was excreted into the milk of cynomolgous monkeys at concentrations of less than 0.5% of those detected in plasma.
Se je pa mepolizumab izločal v mleku opic cynomolgus, in sicer v koncentraciji, ki je bila manj kot 0,5 % koncentracije v plazmi.
However, mineral oil must not be applied for at least two hours before or after the application of Panretin.
Mineralnega olja pa ne smete nanašati najmanj dve uri pred ali po nanosu zdravila Panretin gel.
However, monitoring of anti-Xa activity should be considered in patients treated with low molecular weight heparin with increased risk of bleeding (e.g., patients with renal impairment, elderly or with extreme body weight) or active bleeding.
Vendar je treba o nadziranju aktivnosti anti-Xa razmisliti pri bolnikih, ki prejemajo nizkomolekularni heparin in ki imajo bodisi povečano tveganje za krvavitev (npr. bolniki z ledvično okvaro, starejši bolniki ali bolniki s skrajnostmi telesne mase) bodisi aktivno krvavitev.
However, monitoring of anti-Xa activity should be considered in patients treated with low molecular weight heparin with increased risk of bleeding (e.g., patients with renal impairment, elderly or with extreme body weight) or active bleeding.
Vendar je treba o nadziranju aktivnosti anti-Xa razmisliti pri bolnikih, ki prejemajo nizkomolekularni heparin in ki imajo povečano tveganje za krvavitev (npr. bolniki z ledvično okvaro, starejši bolniki ali bolniki s skrajnostmi telesne mase) ali aktivno krvavitev.
However, monitoring of creatine kinase is recommended.
Vseeno je kreatin kinazo priporočljivo spremljati.
However, most adverse reactions are mild and transient, resolving within 30 minutes after receiving Rapiscan.
Vendar pa je večina neželenih učinkov blagih in prehodnih ter izzvenijo v 30 minutah po uporabi zdravila Rapiscan.
However, neurological disorders (such as cerebellar symptoms, diplopia, lateral nystagmus, psychomotor slowdown, hand movements and axial hypotonia) have been observed in children who had been voluntarily prescribed more than 2.5 times the maximum recommended dose of 100 mg/kg/day for several years.
Nevrološke motnje (kot so cerebelarni simptomi, diplopija, lateralni nistagmus, upočasnjena pshihomotorika, premikanje rok in aksialna hipotonija) so opazili pri otrocih – prostovoljcih, ki so jim nekaj let predpisovali več kot 2,5 kratni največji priporočen odmerek, 100 mg/kg/dan.
However, neurological disorders (such as cerebellar symptoms, diplopia, lateral nystagmus, psychomotor slowdown, hand movements and axial hypotonia) have been observed in children who had been voluntarily prescribed more than 2.5 times the maximum recommended dose of 100 mg/kg/day for several years.
Nevrološke motnje (kot so cerebelarni simptomi, diplopija, lateralni nistagmus, upočasnjena pshihomotorika, premikanje rok in aksialna hipotonija) so opazili pri otrocih – prostovoljcih, ki so jim nekaj let predpisovali več kot 2,5-kratni največji priporočen odmerek, 100 mg/kg/dan.
However, nicotinic acid a component of Trevaclyn does pass into breast milk.
Znano pa je, da v materino mleko prehaja nikotinska kislina, sestavina zdravila Trevaclyn.
However, no apparent toxicity, such as immune complex-mediated disease or complement-dependent cytotoxicity, was seen.
Vendar niso opazili nikakršne nedvoumne toksičnosti, na primer bolezni, v katero je vpleten imunski kompleks, ali od komplementa odvisne citotoksičnosti.
However, no clinically significant QT prolongation compared to placebo + OBT was seen in the Phase 3 clinical studies using the recommended dose of maraviroc or in a specific pharmacokinetic study to evaluate the potential of maraviroc to prolong the QT interval.
Vendar pa v kliničnih študijah 3. faze, v katerih so uporabljali priporočeni odmerek maraviroka, in v specifični farmakokinetični študiji za oceno potenciala maraviroka za podaljšanje intervala QT, niso ugotovili klinično pomembnega podaljšanja QT v primerjavi s placebom+ OOT.
However, no dosage adjustment is required when ibandronic acid is administered with H2-antagonists or medicinal products that increase gastric pH.
Pri sočasnem jemanju ibandronske kisline s H -antagonisti ali zdravili, ki zvečajo pH želodca, pa prilagajanje odmerkov ni
However, no dose adjustment is considered to be necessary based on obesity alone.
Vendar pa velja, da samo na osnovi debelosti prilagajanje odmerka ni potrebno.
However, no dose adjustment is required on the basis of ethnicity (see section 5.2).
Vendar odmerka ni treba prilagoditi glede na etnično pripadnost (glejte poglavje 5.2).
However, no effect of fluoxetine or paroxetine was seen in two of these studies, making the results difficult to interpret.
Vendar je glede na to, da v dveh od teh študij niso bili ugotovljeni nobeni učinki fluoksetina ali paroksetina, te rezultate težko pojasniti.
However, no effects on general development, growth, sensory, cognitive function and reproductive performance were detected at 7 (males) and 19 (females) times the human therapeutic exposure at Day 21 post partum.
Kljub temu pa na 21. dan po skotitvi niso opazili nobenih učinkov na splošni razvoj, rast, senzorne in kognitivne funkcije ter na reproduktivno sposobnost pri 7-kratniku (samci) in 19-kratniku (samice) terapevtske izpostavljenosti pri ljudeh.
However, no effects on general development, growth, sensory, cognitive function and reproductive performance were detected at 7 (males) and 19 (females) times the human therapeutic exposure at Day 21 post partum.
Kljub temu pa na 21. dan po skotitvi niso opazili nobenih učinkov na splošni razvoj, rast, senzorne in kognitivne funkcije ter na reproduktivno sposobnost pri 7-kratniku (samci) in 19-kratniku (samice) terapevtskeizpostavljenosti pri ljudeh.
However, no evidence of clinically significant adverse reactions was observed in the PLATO trial after concomitant administration with one or more medicinal products known to induce bradycardia (e.g.
Vendar pa v preskušanju PLATO po sočasni uporabi z enim ali več zdravili, za katera je znano, da povzročajo bradikardijo (npr.
However, no increased risk for malformations or adverse effects on fertility were noted.
Vendar pa niso opazili večjega tveganja za malformacije ali neželene učinke na plodnost.
However, no significant difference between Cimzia and placebo was seen regarding a reduction in the worsening of joint damage.
Vendar pa ni bilo opaziti nobene bistvene razlike med zdravilom Cimzia in placebom z vidika zmanjševanja napredovanja okvar sklepov.
However, no significant differences were identified in the occurrence of anaemia, thrombocytopenia and episodes of neutropenic fever.
Vendar pa niso opazili pomembnih razlik v pojavnosti anemije, trombocitopenije in epizod nevtropenične vročine.
However, no significant effect on fracture rates was demonstrated.
Vendar niso pokazali značilnega vpliva na razmerja zlomov.
However, no studies involving the interaction with anti- parkinson agents and tricyclic antidepressants have been performed.
Vendar študij, ki bi obravnavale interakcije z antiparkinsoniki in tricikličnimi antidepresivi, niso opravili.
However, no undesirable effects were seen in the testes or ovaries of monkeys given nelarabine intravenously at doses up to approximately 32 % of the adult human dose on a mg/m2 basis for 30 consecutive days.
Pri opicah, ki so 30 zaporednih dni prejemale nelarabin intravensko v odmerkih, ki so na osnovi mg/m2 predstavljali približno do 32 % odmerka za odrasle bolnike, niso opazili neželenih učinkov na moda ali jajčnike.
However, norfloxacin and metronidazole combined reduced the MPA exposure by approximately 30% following a single dose of CellCept.
Kombinacija norfloksacina in metronidazola pa je zmanjšala izpostavljenost mikofenolni kislini za približno 30 % po enkratnem odmerku zdravila CellCept.
However, norfloxacin and metronidazole combined reduced the MPA exposure by approximately 30% following a single dose of mycophenolate mofetil.
Kombinacija norfloksacina in metronidazola pa zmanjša izpostavljenost mikofenolni kislini za približno 30 % po enkratnem odmerku mofetilmikofenolata.
However, olanzapine (5- 20 mg) demonstrated a comparable safety profile in female (n=467) as in male patients (n=869).
Vendar pa je olanzapin (5-20 mg) pokazal primerljiv profil varnosti tako pri bolnikih ženskega (n = 467) kot moškega spola (n = 869).
However, olanzapine (5-20 mg) demonstrated a comparable safety profile in female (n = 467) as in male patients (n = 869).
Vendar pa je olanzapin (5- 20 mg) pokazal primerljiv profil varnosti tako pri bolnikih ženskega (n = 467) kot moškega spola (n = 869).
However, olanzapine (5-20 mg) demonstrated a comparable safety profile in female (n=467) as in male patients (n=869).
Vendar pa je olanzapin (5- 20 mg) pokazal primerljiv profil varnosti tako pri bolnikih ženskega (n = 467) kot moškega spola (n = 869).
However, olanzapine (5-20 mg) demonstrated a comparable safety profile in female (n=467) as in male patients (n=869).
Vendar pa je olanzapin (5-20 mg) pokazal primerljiv profil varnosti tako pri bolnikih ženskega (n = 467) kot moškega spola (n = 869).
However, on the basis of reported adverse reactions, patients should be advised against driving or using machines during treatment.
Vendar morate na osnovi neželenih učinkov, o katerih so poročali, bolnikom odsvetovati vožnjo ali upravljanje strojev med zdravljenjem.
However, on-treatment HBV DNA response was not maintained off-therapy since all the patients had a rebound in HBV DNA after adefovir dipivoxil and pegylated interferon alpha-2a discontinuation.
Vendar pa se odziv HBV DNA dosežen med zdravljenjem ni vzdrževal po prekinitvi zdravljenja, saj se je pri vseh bolnikih po prekinitvi dipivoksiladefovirata in pegiliranega interferona alfa-2a pojavil povratni odziv HBV DNA.
However, once the majority of CD20 cells are bound with obinutuzumab, the impact of TMDD on PK is minimized.
Ko pa je večina CD20+ celic vezana z obinutuzumabom, se vpliv TMDD na farmakokinetiko minimizira.
However, one reported case in a patient treated with Odomzo 800 mg in a non-pivotal study was confirmed.
Za razliko od te študije pa so v študiji, ki ni bila ključna, poročali o enem potrjenem primeru pri bolniku, ki je prejemal zdravilo Odomzo v odmerku 800 mg.
However, only 11% (17/160) of patients in clinical trials with Zyclara required rest periods (treatment interruption) due to local adverse reactions.
Vendar pa je bilo treba le pri 11 % (17/160) bolnikov, ki so sodelovali v klinični preskušanjih zdravila Zyclara, prekiniti obdobja zdravljenje zaradi lokalnih neželenih učinkov.
However, only 65 % of patients were receiving a PI based regimen at study entry.
Vendar pa je ob vstopu v študijo zdravljenje le pri 65 % bolnikov temeljilo na PI-ju.
However, only a small fraction (10–20%) of the overall variability in the pharmacokinetics of the norelgestromin and EE following application of EVRA may be associated with any or all of the above demographic parameters.
Vendar pa lahko le majhen del (10-20 %) celotne variabilnosti v farmakokinetiki norelgestromina in etinilestradiola po namestitvi obliža EVRA povežemo s katerimkoli oz. vsemi zgoraj omenjenimi demografskimi parametri.
However, only one injection should be taken in a 24-hour period.
Vendar pa lahko v roku 24 ur vzamete le eno injekcijo.
However, only one injection should be taken in a 24-hour period.
Vendar pa se lahko v roku 24 ur vzame le eno injekcijo.
However, only press the button when you need pain relief.
Vendar pritisnite gumb samo, kadar potrebujete lajšanje bolečine.
However, opioid analgesics impair the mental and/or physical ability required for the performance of potentially dangerous tasks (e.g., driving a car or operating machinery).
Vendar pa opioidni analgetiki vplivajo na mentalno in/ali fizično sposobnost, potrebno za opravljanje potencialno nevarnih nalog (npr. vožnja avtomobila ali upravljanje strojev).
However, other medicinal products should not be added to the MabCampath infusion or simultaneously infused through the same intravenous line.
Infuzijski raztopini zdravila MabCampath se ne sme dodajati drugih zdravil ali jih infundirati istočasno po isti intravenski liniji.
However, owing to the nephrotoxic potential of tacrolimus, careful monitoring of renal function is recommended (including serial serum creatinine concentrations, calculation of creatinine clearance and monitoring of urine output).
Vendar je zaradi nefrotoksičnega potenciala takrolimusa priporočljivo skrbno nadziranje delovanja ledvic (vključno z rednim določanjem koncentracije kreatinina v serumu, izračunavanjem očistka kreatinina in nadziranjem izločanja urina).
However, PAH seemed to remain stable in almost all of the children during the 12 or 24 weeks of treatment periods.
Vendar pa je bilo videti, da je pljučna arterijska hipertenzija ostala stabilna pri skoraj vseh otrocih v 12 ali 24 tednih zdravljenja.
However, para-aminosalicylic acid appears to be a weak inhibitor of DHP in vitro, raising the possibility that it may have a different target.
Vendar pa se zdi, da je para-aminosalicilna kislina in vitro šibek zaviralec DHP, zato obstaja možnost, da ima drug cilj.
However, patients aged between 65 and 75 years or patients with kidney or liver problems may use Zypadhera if an effective and well- tolerated dose of oral olanzapine has been found.
Kljub temu pa lahko bolniki, stari od 65 do 75 let, ali bolniki z ledvičnimi oziroma jetrnimi težavami zdravilo Zypadhera uporabljajo, če je bil ugotovljen odmerek peroralnega olanzapina, ki je učinkovit in ga bolniki dobro prenašajo.
However, patients experiencing administration-related symptoms (see section 4.4) should be advised not to drive and use machines until symptoms abate.
Bolnikom, pri katerih se pojavijo simptomi, povezani z dajanjem zdravila (glejte poglavje 4.4), je treba svetovati, naj ne vozijo avtomobilov ali upravljajo strojev, dokler ti ne izzvenijo.
However, patients experiencing infusion-related symptoms (see section 4.4) should be advised not to drive and use machines until symptoms abate.
Bolnikom, pri katerih se pojavijo simptomi, povezani z infundiranjem (glejte poglavje 4.4), je treba svetovati, naj ne vozijo avtomobilov ali upravljajo strojev, dokler ti ne izzvenijo.
However, patients should be advised to use a multivitamin supplement at bedtime to help ensure adequate vitamin intake (see section 4.4).
Vseeno je treba bolnikom svetovati, naj pred spanjem za zagotovitev ustreznega vnosa vitaminov vzamejo multivitaminski nadomestek (glejte poglavje 4.4).
However, patients should be carefully monitored for signs and symptoms of myopathy and rhabdomyolysis when co-treated with pravastatin, rosuvastatin and fluvastatin.
Bolnike je treba med sočasnim zdravljenjem s pravastatinom, rosuvastatinom in fluvastatinom natančno spremljati glede znakov in simptomov miopatije in rambomiolize.
However, patients should be informed that dizziness has been reported during treatment with dolutegravir.
Vendar pa je treba bolnike obvestiti, da so med zdravljenjem z dolutegravirjem poročali o omotici.
However, patients should be informed that dizziness has been reported during treatment with Stribild.
Vendar je bolnike potrebno opozoriti, da se lahko v času zdravljenja z zdravilom Stribild pojavi omotičnost.
However, patients should be informed that dizziness has been reported during treatment with tenofovir disoproxil fumarate.
Vendar je bolnike potrebno opozoriti, da se lahko v času zdravljenja z dizoproksiltenofovirijevim fumaratom pojavi omotičnost.
However, patients should be informed that dizziness has been reported from literature, but not commonly.
Vseeno pa je treba bolnike obvestiti, da so v literaturi poročali o vrtoglavici, vendar ne pogosto.
However, patients should exercise caution when driving or operating hazardous machinery, especially when starting treatment with vortioxetine or when changing the dose.
Vendar pa morajo biti bolniki previdni pri vožnji ali upravljanju s stroji, še posebej na začetku zdravljenja z vortioksetinom ali ob spremembi odmerka.