natgillin/translations-raw huggingface dataset:
However, patients with age >75 years are potentially at risk for a higher frequency of serious adverse reactions.
Vendar pa je pri bolnikih, starejših od 75 let, možno tveganje večje pogostnosti resnih neželenih učinkov.
However, patients with ESRD requiring dialysis exhibited a 43.5% reduction in nevirapine AUC over a one-week exposure period.
Pri bolnikih s končno fazo ledvične bolezni, ki so se morali zdraviti z dializo, pa se je AUC nevirapina v enem tednu jemanja zmanjšala za 43,5 %.
However, physiology-based pharmacokinetic modelling does not predict any relevant change in exposure in these patients.
Kljub temu se iz farmakokinetičnega modeliranja na osnovi fiziologije pri teh bolnikih ne da sklepati na določene spremembe v izpostavljenosti.
However, pilomatricoma (a benign cutaneous neoplasm) was observed in the 26 week rat toxicity study.
A v 26-tedenski študiji toksičnosti pri podganah so opazili pilomatrikome (benigne kožne novotvorbe).
However, please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.
Obvestite zdravnika ali farmacevta, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo, tudi če ste ga dobili brez recepta.
However, post hoc analyses demonstrated that changes from baseline in cardiopulmonary hemodynamic parameters for the tadalafil 40 mg treatment group were not significantly different compared to placebo.
Post-hoc analize so pokazale, da se vrednosti parametrov srčno-pljučnega pretoka glede na osnovno vrednost pri skupini, ki se je zdravila s tadalafilom 40 mg, v primerjavi s placebom niso znatno razlikovale.
However, post- hoc analysis of data from the two Phase 3 clinical trials showed that the pharmacokinetics of regadenoson were not affected in a small subset of patients with laboratory values suggestive of impaired hepatic function (2.5-fold transaminase elevation or 1.5-fold elevation of serum bilirubin or prothrombin time).
Vendar pa analiza post-hoc na podlagi podatkov iz dveh kliničnih preskušanj 3. faze kaže, da farmakokinetika regadenozona ni bila prizadeta v majhni podskupini bolnikov z laboratorijskimi vrednostmi, ki kažejo na okvaro jeter (2,5- kratni zvečanje transaminaze ali 1,5-kratni zvečanje serumskega bilirubina ali protrombinskega časa).
However, precautionary measures have to be followed in order to avoid direct or indirect contact between vaccinated chickens and turkeys.
Potrebno pa je upoštevati vse varnostne ukrepe, da bi se izognili neposrednemu ali posrednemu stiku med cepljenimi piščanci in purani.
However, pregnancy must be ruled out before IOA use is continued, if IOA has not been taken as directed or if two consecutive withdrawal bleedings are missed.
Če pa zdravila IOA ni jemala v skladu z navodili ali če ni imela dveh zaporednih odtegnitvenih krvavitev, je treba izključiti nosečnost, preden lahko nadaljuje z jemanjem zdravila IOA.
However, protection of Eptifibatide Accord solution from light is not necessary during administration.
Zaščita raztopine zdravila Eptifibatide Accord pred svetlobo med uporabo ni potrebna.
However, protection of Integrilin solution from light is not necessary during administration.
Zaščita raztopine Integrilin pred svetlobo med uporabo ni potrebna.
However, raltegravir is secreted in the milk of lactating rats.
Pri doječih podganah se raltegravir izloča v mleko.
However, rare spontaneous reports of HIT in patients treated with fondaparinux have been received.
vendar pa so bila pridobljena redka spontana poročila o HIT pri bolnikih, ki so se zdravili s fondaparinuksom.
However, reduced renal function is a risk factor for bleeding and should be considered before initiating Zontivity.
Zmanjšano delovanje ledvic je dejavnik tveganja za krvavitve in ga je treba upoštevati pred uvedbo zdravila Zontivity.
However, reduction of LDL-C is maintained during the dosing interval when alirocumab is administered every two weeks.
Kljub temu se znižanje LDL-H ohrani skozi celoten odmerni interval, če je alirokumab uporabljan na dva tedna.
However, reduction of the QRS complex is considered more indicative of cardiac toxicity.
Vendar pa se šteje zmanjšanje kompleksa QRS bolj za znak srčne toksičnosti.
However, relapse following seroconversion can occur.
Vendar lahko po serokonverziji pride do relapsa.
However, renal function was not changed due to prior irreversible kidney damage (Table 11).
Vendar pa zaradi predhodno nastale ireverzibilne okvare ledvic ni prišlo do sprememb ledvične funkcije (preglednica 11).
However, reports following relatively short- term use also exist.
Poročajo pa tudi o pojavljanju po relativno kratkem času uporabe.
However, reports of hepatic decompensation and hepatic failure during OLYSIO combination therapy have been received in the post marketing setting (see section 4.4).
Vendar so v obdobju trženja ob zdravljenju z zdravilom Olysio poročali o dekompenzaciji jeter in jetrni odpovedi (glejte poglavje 4.4).
However, reproductive studies have been conducted with Kineret on rats and rabbits at doses up to 100 times the human RA dose and have revealed no evidence of impaired fertility or harm to the foetus.
Vendar so bile z zdravilom Kineret opravljene študije sposobnosti razmnoževanja pri podganah in kuncih z odmerki do 100-kratnika odmerka pri človeku, ki niso dale dokazov o zmanjšani plodnosti ali škodljivosti za plod.
However, reproductive studies have been conducted with Kineret on rats and rabbits at doses up to 100 times the human RA dose and have revealed no evidence of impaired fertility or harm to the foetus.
Vendar so bile z zdravilom Kineret opravljene študije sposobnosti razmnoževanja pri podganah in kuncih z odmerki do 100-kratnika odmerka RA pri človeku, ki niso dale dokazov o zmanjšani plodnosti ali škodljivosti za plod.
However, retapamulin showed no advantage over placebo in subjects with SIOW due to S. pyogenes.
Pri preizkušancih s sekundarnimi okužbami odprtih ran s S. pyogenes pa retapamulin ni pokazal nobenih prednosti v primerjavi s placebom.
However, RoActemra can be given alone if your doctor determines that methotrexate is inappropriate.
Vendar je mogoče zdravilo RoActemra uporabljati tudi samo, če vaš zdravnik presodi, da metotreksat za vas ni primeren.
However, seek immediate medical help if you notice any of the following: severe weakness, fainting, abdominal pain, nausea, vomiting, back pain, confusion, reduced consciousness, delirium (very confused state).
Takoj pa poiščite zdravniško pomoč, če opazite kaj od naslednjega: huda šibkost, omedlevica, bolečine v trebuhu, slabost s siljenjem na bruhanje (navzea), bruhanje, bolečina v hrbtu, zmedenost, zmanjšana stopnja zavesti, delirij (stanje močne zmedenosti).
However, several independent studies have demonstrated the 135mcg dose to be safe, efficacious and well tolerated, in patients with ESRD. (see section 4.2).
Vendar pa so številne neodvisne študije pokazale, da je odmerek 135 µg za bolnike s končno ledvično odpovedjo varen, učinkovit in dobro prenosljiv.
However, several independent studies have demonstrated the 135mcg dose to be safe, efficacious and well tolerated, in patients with ESRD.(see section 4.2).
Vendar pa so številne neodvisne študije pokazale, da je odmerek 135 µg za bolnike s končno ledvično odpovedjo varen, učinkovit in dobro prenosljiv.
However, several reports of hypoglycaemia with related hypoglycaemic seizure were reported during the compassionate use program and in literature, especially in case of fasting period during intercurrent illness (see section 4.4).
Vseeno pa so poročali o nekaj primerih hipoglikemije s povezanim hipoglikemičnim napadom med programom sočutne uporabe in v literaturi, zlasti v primeru obdobja posta med sočasno boleznijo (glejte poglavje 4.4).
However, shampooing or immersion of the animal in water directly after treatment or frequent shampooing may reduce the duration of activity.
Šamponiranje, stik živali z vodo neposredno po nanosu zdravila ali pogosto šamponiranje lahko skrajšajo delovanje zdravila.
However, should very high dose cutaneous administration or accidental oral ingestion occur, attention should be paid to the effects seen with therapeutic doses of intravenous eflornithine (400 mg/kg/day or approximately 24 g/day) used in the treatment of Trypanosoma brucei gambiense infection (African sleeping sickness): hair loss, facial swelling, seizures, hearing impairment, gastrointestinal disturbance, loss of appetite, headache, weakness, dizziness, anaemia, thrombocytopenia and leucopenia.
Vendar pa moramo biti v primeru zelo visokih odmerkov pri dermalni aplikaciji ali zaužitju zdravila po pomoti pozorni na učinke, vidne pri intravenskem dajanju zdravila v terapevtskih odmerkih (400 mg/kg/dan ali približno 24 g/dan) pri zdravljenju infekcij s Trypanosoma brucei gambiense (afriška spalna bolezen): izguba las, otekanje obraza, krči, okvara sluha, prebavne motnje, izguba apetita, glavobol, slabost, vrtoglavica, anemija, trombocitopenija in levkopenija.
However, since Akynzeo contains a 5-HT3 receptor antagonist, caution should be exercised in concomitant use with medicinal products that increase the QT interval or in patients who have or are likely to develop prolongation of the QT interval.
Ker pa zdravilo Akynzeo vsebuje antagonist receptorjev 5-HT3 , je potrebna previdnost pri sočasni uporabi z zdravili, ki podaljšujejo interval QT, ali pri bolnikih, ki so razvili podaljšan interval QT, oziroma je verjetno, da ga bodo.
However, since amprenavir is highly protein bound, dialysis is unlikely to be helpful in reducing blood levels of amprenavir.
Ker se amprenavir močno veže na proteine, je malo verjetno, da bi dializa koristila pri zniževanju njegovih vrednosti v krvi.
However, since Bemfola is not indicated in pregnancy, these data are of limited clinical relevance.
Vendar imajo ti podatki le omejen klinični pomen, ker zdravilo Bemfola ni indicirano v nosečnosti.
However, since erythema multiforme differs in clinical pattern and aetiology from SJS, the MAH is requested to add “erythema multiforme” to the ADR table in section 4.8 of the SmPCs.
Ker pa se multiformni eritem klinično in etiološko razlikuje od Stevens-Johnsonovega sindroma, mora imetnik dovoljenja za promet z zdravilom v tabelo neželenih učinkov v poglavju 4.8 povzetkov glavnih značilnosti zdravil dodatno navesti še “multiformni eritem”.
However, since excretion in urine is minimal and the major route of elimination is via the faeces, renal impairment is not expected to affect the pharmacokinetics of radium-223 dichloride.
Ker se izloča v majhnih količinah s sečem in večinoma z blatom, ni pričakovati, da bi ledvična okvara vplivala na farmakokinetiko [223Ra]radijevega klorida.
However, since no DPD inducers are currently known, the interaction between a DPD inducer and Teysuno cannot be evaluated.
Ker trenutno ni na voljo nobenega induktorja DPD, ni mogoče ovrednotiti medsebojnega delovanja induktorja DPD in zdravila Teysuno.
However, since plasma concentrations of retapamulin during topical application have been low (see section 5.2), it is not expected that concurrent systemic administration of CYP3A4 substrates will result in clinically important inhibition of their metabolism by retapamulin.
Vendar je bila koncentracija retapamulina v plazmi med lokalno uporabo majhna (glejte poglavje 5.2), zato ni pričakovati, da bi retapamulin pomembno zavrl presnovo sočasno sistemsko uporabljenih substratov CYP3A4.
However, since renal function is known to decline with age, elderly patients may show reduced elimination of enoxaparin sodium (see sections 4.2, 4.4 and 5.2).
Ker pa je znano, da se ledvična funkcija s starostjo zmanjšuje, je izločanje natrijevega enoksaparinata pri starejših bolnikih lahko upočasnjeno (glejte poglavje 4.2, 4.4 in 5.2).
However, since side effects might occur, any treatment exceeding 1 – 2 weeks should be under regular veterinary supervision.
Ker se lahko pojavijo neželeni učinki, mora biti zdravljenje, ki je daljše od 1 do 2 tednov, pod rednim veterinarskim nadzorom.
However, since the clinical
Ker pa kliničnega pomena
However, since the effects of low-dose exposure of the infant to imatinib are unknown, women taking imatinib should not breast- feed.
Vendar učinki izpostavljenosti dojenčka majhnim odmerkom imatiniba niso znani, zato ženske, ki jemljejo imatinib ne smejo dojiti.
However, since the effects of low-dose exposure of the infant to imatinib are unknown, women taking imatinib should not breast- feed.
Vendar učinki izpostavljenosti dojenčka nizkim odmerkom imatiniba niso znani, zato ženske, ki jemljejo imatinib ne smejo dojiti.
However, since the main study did not compare Blincyto to other standard treatments, the CHMP considered that further data were needed.
Ker pa v glavni študiji zdravila Blincyto niso primerjali z drugimi standardnimi oblikami zdravljenja, je menil, da so potrebni dodatni podatki.
However, since the medicine has a different mode of action, few side effects and a different safety profile to existing antidepressants, the Committee concluded that Valdoxan could be a valuable treatment for some patients as long as their liver function is tested frequently.
Vendar je glede na drugačen način delovanja zdravila, nizko število neželenih učinkov in drugačen varnostni profil v primerjavi z obstoječimi antidepresivi, zaključil, da bi bilo zdravilo Valdoxan lahko pomembno za zdravljenje nekaterih bolnikov, pri čemer pa bi bilo treba redno preverjati delovanje jeter.
However, since this increase is within the normal variability of the bioavailability of ibandronic acid, no dose adjustment is considered necessary when Bondenza is administered with H2- antagonists or other active substances which increase gastric pH.
Ker je to zvečanje v mejah normalne variabilnosti biološke uporabnosti ibandronske kisline, pri sočasnem jemanju zdravila Bondenza z antagonisti histaminskih receptorjev H2 ali drugimi zdravili, ki zvečajo pH želodca, prilagajanje odmerkov ni potrebno.
However, since this increase is within the normal variability of the bioavailability of ibandronic acid, no dose adjustment is considered necessary when Bonviva is administered with H2- antagonists or other active substances which increase gastric pH.
Ker je to zvečanje v mejah normalne variabilnosti biološke uporabnosti ibandronske kisline, pri sočasnem jemanju zdravila Bonviva z antagonisti histaminskih receptorjev H2 ali drugimi zdravili, ki zvečajo pH želodca, prilagajanje odmerkov ni potrebno.
However, since this increase is within the normal variability of the bioavailability of ibandronic acid, no dose adjustment is considered necessary when Ibandronic Acid Teva is administered with H2-antagonists or other active substances which increase gastric pH.
Ker je to povečanje v mejah normalne variabilnosti biološke uporabnosti ibandronske kisline, pri sočasnem jemanju zdravila Ibandronska kislina Teva s H2-antagonisti ali drugimi zdravili, ki povečajo vrednost pH v želodcu, prilagajanje odmerkov ni potrebno.
However, since TMZ does not undergo hepatic metabolism and exhibits low protein binding, it is unlikely that it would affect the pharmacokinetics of other medicinal products (seesection 5.2).
Vendar, ker se TMZ ne presnavlja v jetrih in ker se v majhni meri veže na beljakovine, ni verjetno, da bi vplival na farmakokinetiko drugih zdravil (glejte poglavje 5.2).
However, single inhaled doses up to 6,000 µg aclidinium bromide have been administered to healthy subjects without systemic anticholinergic adverse effects.
Vendar enkratni inhalacijski odmerek do 6.000 µg aklidinijevega bromida pri zdravih prostovoljcih, ni imel neželenih sistemskih antiholinergičnih učinkov.
However, so far the available data are insufficient and do not identify specific risks for the unborn child.
Vendar pa so do zdaj razpoložljivi podatki nezadostni in ne določajo specifičnih tveganj za nerojenega otroka.
However, so far, no interactions with other medicines have been reported during treatment with Dynepo.
Doslej med zdravljenjem z Dynepom ni bilo opisanih medsebojnih delovanj z drugimi zdravili.
However, some cases of marked rises in CPK levels and cases of rhabdomyolysis occurred in patients taking one of these medicinal products at the same time as Cubicin.
Vendar pa je pri bolnikih, ki so jemali ta zdravila sočasno z zdravilom Cubicin, v nekaj primerih prišlo do izrazitega porasta ravni CPK in do nekaj primerov rabdomiolize.
However, some of the effects mentioned under section 4.8 “Undesirable effects” may affect the ability to drive or use machines.
Toda nekateri učinki, omenjeni v poglavju 4.8 "Neželeni učinki", lahko poslabšajo sposobnost vožnje in upravljanja s stroji.
However, some of the effects mentioned under section 4.8 “Undesirable effects” may temporarily affect the ability to drive or use machines.
Vendar lahko nekateri učinki, omenjeni v poglavju 4.8, začasno vplivajo na sposobnost vožnje ali upravljanja s stroji.
However, some of the effects mentioned under section 4.8. “Undesirable effects” may temporarily affect the ability to drive or use machines.
Vendar lahko nekateri učinki, omenjeni v poglavju 4.8, začasno vplivajo na sposobnost vožnje ali upravljanja s stroji.
However, some of the side effects you may experience while using Signifor, such as headache and tiredness, may reduce your ability to drive and use machines safely.
Vendar nekateri neželeni učinki, do katerih lahko pride med uporabo zdravila Signifor, kot sta glavobol in utrujenost, lahko zmanjšujejo sposobnost upravljanja vozil in strojev.
However, some of the side effects you may experience while using Signifor, such as headache, dizziness and tiredness, may reduce your ability to drive and use machines safely.
Vendar nekateri neželeni učinki, do katerih lahko pride med uporabo zdravila Signifor, kot so glavobol, omotičnost in utrujenost, lahko zmanjšujejo sposobnost upravljanja vozil in strojev.
However, some of these reactions may be serious or life- threatening and several patients with blast crisis died with a complex clinical history of pleural effusion, congestive heart failure and renal failure.
Vendar so nekatere od teh reakcij lahko resne ali smrtno nevarne.Več bolnikov z blastno krizo je namreč umrlo z zapleteno klinično anamnezo plevralnega izliva, kongestivnega popuščanja srca in ledvične odpovedi.
However, some patients who show no response after 8 weeks of treatment with STAYVEER may respond favourably after an additional 4 to 8 weeks of treatment.
Nekateri bolniki, ki po 8 tednih zdravljenja z zdravilom STAYVEER ne pokažejo nobenega odziva, se lahko ugodno odzovejo po dodatnih 4 ali 8 tednih zdravljenja.
However, sometimes your doctor may recommend a lower dose 20 mg or a higher dose of 80 mg.
Včasih pa vam lahko zdravnik svetuje manjši odmerek 20 mg telmisartana ali večji 80 mg.
However, sometimes your doctor may recommend a lower dose of 20 mg or a higher dose of 80 mg.
Vaš zdravnik vam je predpisal eno 40 mg tableto dnevno.
However, sometimes your doctor may recommend a lower dose of 20 mg or a higher dose of 80 mg.
Zdravnik lahko priporoči tudi manjši odmerek po 20 mg ali večji odmerek po 80 mg.
However, sometimes your doctor may recommend a lower dose of 20 mg or a higher dose of 80 mg.
Zdravnik lahko priporoči tudi manjši odmerek po 20 mg enkrat na dan.
However, sometimes your doctor may recommend a lower dose of 20 mg or a higher dose of 80 mg.
Zdravnik lahko priporoči tudi manjši odmerek po 20 mg, ali večji odmerek po 80 mg.
However, sometimes your doctor may recommend a lower dose of 20 mg or a higher dose of 80 mg.
Zdravnik vam lahko svetuje manjši odmerek 20 mg telmisartana ali večji odmerek 80 mg.
However, special caution is advised and dose adjustments may be necessary in these patients since systemic exposure is probably increased and the risk of hepatotoxicity might be increased.
Kljub temu se priporoča posebna previdnost in morda bo pri teh bolnikih potrebna prilagoditev odmerka, saj se sistemska izpostavljenost verjetno poveča, s čemer verjetno naraste tudi tveganje hepatotoksičnosti.
However, stability has been demonstrated when stored outside the refrigerator for up to 3 days at temperatures between 8°C and 25°C or for up to 1 day at temperatures between 25°C and 37°C. If not used at the end of this period the vaccine should be discarded.
Vendar je bila stabilnost dokazana, tudi če je bilo shranjeno zunaj hladilnika, in sicer do 3 dni pri temperaturi od 8 °C do 25 °C ali do 1 dan pri temperaturi od 25 °C do 37 °C. Če se cepiva ne uporabi do konca tega obdobja, ga je treba zavreči.
However, STAYVEER may induce hypotension, with symptoms of dizziness, blurred vision or syncope that could affect the ability to drive or use machines.
Zdravilo STAYVEER lahko povzroči hipotenzijo s simptomi omotice, zamegljenega vida ali sinkope, ki bi lahko vplivala na sposobnost vožnje in upravljanja s stroji.
However, studies conducted in girls aged 9 to 14 years (study HPV-071) and in women aged 18 to 45 years (study HPV-010) have consistently shown a higher immune response with Cervarix than with the comparator for which efficacy data against anal premalignant lesions are conclusive and have shown protection.
Toda študije, izvedene pri dekletih v starosti od 9 do 14 let (študija HPV-071) in ženskah v starosti od 18 do 45 let (študija HPV-010), so dosledno pokazale večji imunski odziv na cepivo Cervarix kot na primerjalno cepivo, za katero so podatki o učinkovitosti proti analnim predrakavim spremembam trdni in so pokazali zaščito.
However, studies performed in Asian (Japanese) healthy subjects did not reveal a different pharmacokinetic profile compared to Caucasian healthy subjects.
Vendar raziskave z zdravimi osebami v Aziji (Japonci) niso razkrile drugačnega farmakokinetičnega profila, kot ga imajo zdravi belci.
However, studies with laboratory animals have shown embryo- foetotoxicity, malformations, delayed parturition and decreased pup survival.
Študije na laboratorijskih živalih so pokazale embriofetotoksičnost, malformacije, zakasnele porode in zmanjšano preživetje mladičev.
However, studies with laboratory animals have shown embryo-foetotoxicity, malformations, delayed parturition and decreased pup survival.
Študije na laboratorijskih živalih pa so pokazale embriofetotoksičnost, malformacije, zakasnele porode in zmanjšano preživetje mladičev.
However, subject data continued to be collected through the date of the second interim analysis of Overall survival (OS).
Podatke o preiskovancih so še nadalje zbirali do datuma druge vmesne analize celokupnega preživetja.
However, subjects with baseline CD4 >100 cells/mm3, baseline HIV-1 RNA <5.0 log10 copies/ml, ≤ 10 prior ARVs, and/or other active ARVs in their OB regimen were more likely to achieve a HIV-1 RNA of <400 copies/ml (or <50 copies/ml) on either treatment (see Table 6).
Kakor koli so v obeh shemah zdravljenja bolniki z izhodiščnim CD4 > 100 celic/mm3, izhodiščno HIV-1 RNA < 5,0 log kopij/ml, z  10 predhodnimi protiretrovirusnimi zdravili in/ali drugimi aktivnimi protiretrovirusnimi zdravili v shemi optimiziranega temeljnega zdravljenja, verjetneje dosegli HIV-1 RNA < 400 kopij/ml (ali < 50 kopij/ml) (glejte preglednico 6).
However, taken into account:
Vendar pa se ob upoštevanju naslednjega:
However, talk to your doctor or nurse first. you have a bleeding problem or you bruise easily.
Vendar se vseeno najprej posvetujte z zdravnikom ali medicinsko sestro; če imate težave s strjevanjem krvi ali se vam hitro pojavijo podplutbe.
However, Tasmar, as a COMT inhibitor, is known to increase the bioavailability of the co-administered levodopa.
Zdravilo Tasmar, kot COMT zaviralec, zviša biološko uporabnost sočasno dajane levodope.
However, tell your doctor or pharmacist if you think that a dose has been forgotten.
A če se vam zdi, da je bil odmerek pozabljen, to povejte zdravniku ali farmacevtu.
However, tenofovir disoproxil fumarate reduced the viability index and weight of pups in a peri-postnatal toxicity study at maternally toxic doses.
Vendar pa je alafenamidtenofovirat fumarat zmanjšal indeks viabilnosti in telesno maso mladičev v peri- in postnatalni študiji toksičnosti pri odmerkih, toksičnih za mater.