natgillin/translations-raw huggingface dataset:
Swelling of the hands, ankles or feet is more common (in less than 1 in 10 users) when Ipreziv is taken with amlodipine (a calcium channel blocker for treating hypertension) than when Ipreziv is taken alone (less than 1 in 100 users).
Zatekanje rok, gležnjev ali nog je bilo pogostejše (pri manj kot 1 od 10 bolnikov), če so zdravilo Ipreziv jemali sočasno z amlodipinom (zaviralec kalcijevih kanalčkov za zdravljenje hipertenzije), kot pa, če so jemali samo zdravilo Ipreziv (manj kot 1 od 100 bolnikov).
Swelling of the hands, feet and legs (peripheral oedema)
vročinski oblivi otekanje dlani, stopal in nog (periferni edem)
Swelling of the hands, feet or ankles
oteklost dlani, stopal ali gležnjev,
Swelling of the joints
oteklost sklepov
Swelling of the layers of skin which can affect any part of the body including the face, tongue or throat and may cause difficulty swallowing or breathing (angioedema)
Otekanje plasti kože, ki lahko prizadane katerikoli del telesa, vključno z obrazom, jezikom ali grlom, in lahko povzroči oteženo požiranje ali dihanje (angioedem).
Swelling of the legs and feet, back pain, reduced passing of water, increased thirst, rapid pulse, dizziness and nausea, vomiting or reduced appetite and feelings of confusion, restlessness or fatigue.
Otekanje spodnjih udov in stopal, bolečina v križu, zmanjšano izločanje urina, zvečana žeja, pospešen srčni utrip, omedlevica in navzea, bruhanje ali zmanjšan tek in občutki zmedenosti, vznemirjenosti ali utrujenosti.
Swelling of the lining of the heart (pericarditis), symptoms include pain behind the breast bone, sometimes spreading across to the neck and shoulders, sometimes with a fever
otekanje ovojnice, ki obdaja srčno votlino (perikarditis), simptomi so bolečine za prsnico, ki se včasih širi po vratu in ramenih, včasih z zvišano telesno temperaturo,
Swelling of the lip (lip oedema)
oteklost ustnic (edem ustnic)
Swelling of the lips
otekanje ustnic;
Swelling of the lips, face, throat or tongue
oteklost ustnic, obraza, žrela ali jezika
Swelling of the liver (hepatitis) or gall bladder, liver damage
otekanje jeter (hepatitis) ali žolčnika, okvara jeter
Swelling of the liver (hepatitis) or gall bladder, liver damage
otekanje jeter (hepatitis) ali žolčnika, okvara jeter,
Swelling of the liver, bleeding from the liver
otekanje jeter, krvavitev v jetrih
Swelling of the lymph glands
otekanje bezgavk,
Swelling of the optic nerve head (papilloedema)
oteklost glave vidnega živca (edem papile)
Swelling of the see-through layer that covers the eye
otekanje prozorne plasti, ki pokriva oko,
Swelling of the surface of the eye
otekanje površine oči,
Swelling of the veins above and behind the testicles (a varicocele)
oteklost žil nad testisi in za njimi (varikokela)
Swelling of your belly (abdomen).
zatečenost trebuha,
Swelling of your face, lips or tongue
oteklina obraza, ustnic ali jezika
Swelling of your face, particularly around your mouth (tongue and/or throat and/or difficulty to swallow) or hives together with difficulties to breathe (angioedema) and/or sudden feeling of faintness.
otekanje obraza, zlasti okrog ust (jezik in/ali žrelo in/ali težave s požiranjem) ali koprivnica, skupaj s težkim dihanjem (angioedem) in/ali nenadnim občutkom omedlevice.
Swelling of your lymph glands
otekle bezgavke
Swelling of your pancreas (pancreatitis)
otekanje trebušne slinavke (pankreatitis)
Swelling of your pancreas (pancreatitis)
otekanje trebušne slinavke (pankreatitis),
Swelling or bleeding at the site of injection, or chest pain after an injection
otekanje ali krvavitev na mestu injiciranja ali bolečina v prsih po injiciranju,
Swelling or bruising at the injection site
oteklina, pojav modric na mestu vboda,
Swelling or infection of the brain (encephalitis)
oteklost ali okužba možganov (encefalitis),
Swelling or infection of the brain (encephalitis)
oteklost ali okužba možganov (encefalitis);
Swelling or inflammation of the brain (encephalopathy/encephalitis).
otekanje ali obolenje možganov (encefalopatija/encefalitis)
Swelling Total
Oteklina skupno
Swelling*
Otekanje
Swelling, blistering or peeling of the skin
otekanje ali luščenje kože oziroma nastanek mehurjev
Swelling, feeling of heaviness or tightness, pain, limited mobility of body parts (this could occur anywhere in the body and is a potential sign of an abnormal build-up of fluid in soft tissue due to a blockage in the lymphatic system, also known as lymphoedema)
otekanje, občutek teže ali zategovanja, bolečine in omejena gibljivost delov telesa (do česar lahko pride na kateremkoli delu telesa in lahko pomeni nenormalno zastajanje tekočine v mehkih tkivih zaradi zapore limfnega sistema, kar imenujemo limfedem)
Swelling, feeling of heaviness or tightness, pain, limited mobility of body parts (this could occur anywhere in the body and is a potential sign of and abnormal build-up of fluid in soft tissue due to a blockage in the lymphatic system, also known as lymphoedema)
otekanje, občutek teže ali zategovanja, bolečine in omejena gibljivost delov telesa (do česar lahko pride na kateremkoli delu telesa in lahko pomeni nenormalno zastajanje tekočine v mehkih tkivih zaradi zapore limfnega sistema, kar imenujemo limfedem)
Swelling, inflammation Stinging, tingling Bleeding
Skelenje, srbenje Krvavenje
Swelling, mainly in the region of the eyelids and the lips (Quincke's oedema) and shock-like allergic reactions with symptoms of tingling, reddening, itching, hot flush and accelerated pulse.
Otekanje, večinoma v predelu oči in ustnic (Quinckejev edem) in šoku podobne alergijske reakcije s simptomi, kot so ščemenje, pordečitev, srbenje, vročinski oblivi in pospešen srčni utrip.
Swelling, pain in your hands and feet, or shortness of breath.
oteklina, bolečina dlani ali stopal ali kratka sapa
Swelling, pain in your hands and feet, or shortness of breath.
oteklina, bolečina v dlaneh in stopalih ali kratka sapa.
Swelling, soreness, redness, induration, local heat, itching, bruising and rash.
Oteklina, občutljivost, rdečina, zatrdlina, lokalna vročica, srbenje, modrice in izpuščaj.
Swensweg 5
Computerweg 10,
Swensweg 5, 2031 GA Haarlem The Netherlands
2031 GA Haarlem Nizozemska
Swensweg 5, 2031 GA Haarlem, Netherlands
2031 GA Haarlem Nizozemska
Swensweg 5, 2031GA Haarlem The Netherlands
2031 GA Haarlem Nizozemska
Swensweg 5, 2031GA Haarlem, The Netherlands.
Swensweg 5, 2031 GA Haarlem, Nizozemska
Swensweg 5, 2031GA HaarlemThe Netherlands
Swensweg 5, 2031 GA Haarlem Nizozemska
Swine dysentery
prašičje dizenterije
Swirl carefully; the content of the vial of Scintimun will dissolve within one minute (DO NOT shake).
Previdno vrtinčite, da se vsebina viale z oznako Scintimun raztopi v roku ene minute (NE stresajte).
Swirl gently until all material is dissolved.
Vsebino sistema previdno zvrtinčite, da se vsebina raztopi.
Swirl gently without removing the syringe.
Rahlo zavrtinčite, ne da bi odstranili injekcijsko brizgo.
Swirl the mixing cup gently to mix for 30 to 60 seconds.
Posodico za mešanje nežno vrtite od 30 do 60 sekund, da se vsebina premeša.
Swirl the syringe- vial assembly gently until the powder is completely dissolved.
Nežno jo obračajte, dokler se prašek povsem ne raztopi.
Swirl the vial gently to aid reconstitution.
Vialo rahlo vrtite do raztopitve.
Swirl the vial gently until the lyophilisate has dissolved.
Vialo nežno vrtite, dokler se liofilizat ne raztopi.
Swirl vial gently to aid reconstitution.
Vialo rahlo vrtite do raztopitve.
Switch between insulin glargine 100 units/ml and Toujeo
Prehod med insulinom glarginom 100 enot/ml in zdravilom Toujeo
Switch between insulin glargine 100 units/ml and Toujeo
Prehod z insulina glargina 100 enot/ml na zdravilo Toujeo
Switch from insulin glargine 300 units/ml to Lantus
Prehod z insulina glargina 300 enot/ml na zdravilo Lantus
Switching
Zamenjava zdravila
Switching (pVTEp orthopaedic surgery)
Zamenjava zdravila (pVTEp pri ortopedski operaciji)
Switching (SPAF, DVT/PE)
Zamenjava zdravila (SPAF, GVT/PE)
Switching a patient between another type or brand of insulin and Toujeo should be done under strict medical supervision.
Prehod bolnika med drugimi vrstami ali znamkami insulinskega zdravila in zdravilom Toujeo sme potekati le pod strogim zdravniškim nadzorstvom.
Switching between antipsychotic medicinal products
Prehod iz zdravljenja ali na zdravljenje z drugim antipsihotikom
Switching between biological DMARDs
Prehod med posameznimi biološkimi antirevmatiki, ki vplivajo na potek bolezni (DMARD)
Switching between biological DMARDS
Prehod na zdravljenje z drugim biološkim zdravilom tipa DMARD
Switching between tablet and oral suspension and vice versa
Prehod med tabletami in peroralno suspenzijo ter obratno
Switching from a TDF-based regimen to Genvoya was superior in maintaining HIV-1 RNA
Prehod z režima na podlagi TDF na zdravilo Genvoya je bil boljši pri ohranjanju HIV-1 RNA
Switching from Aptivus capsules to the oral solution
Prehod z zdravila Aptivus kapsule na peroralno raztopino
Switching from Aptivus oral solution to the capsules
Prehod z zdravila Aptivus peroralna raztopina na kapsule
Switching from capsules or oral solution to transdermal patches
Prehod z zdravljenja s kapsulami ali peroralno raztopino na zdravljenje z obliži
Switching from immediate-release (crystalline) nicotinic acid to Tredaptive has not been studied.
Prehod z nikotinske kisline s takojšnjim sproščanjem (kristalne nikotinske kisline) na zdravilo Tredaptive ni raziskan.
Switching from Lixiana
Zamenjava zdravila Lixiana z drugim antikoagulantom
Switching from once-daily basal insulins to once-daily Toujeo can be done unit-to-unit based on the previous basal insulin dose.
Prehod z bazalnih insulinov enkrat na dan na zdravilo Toujeo enkrat na dan je mogoče izvesti na podlagi enote-za-enoto predhodno uporabljanega odmerka bazalnega insulina.
Switching from oral paliperidone or oral risperidone
Prehod s peroralnega paliperidona ali peroralnega risperidona
Switching from other antipsychotic medicinal products
Prehod z drugih antipsihotičnih zdravil
Switching from other formulations of guanfacine
Prehod z drugih farmacevtskih oblik gvanfacina
Switching from risperidone long acting injection
Prehod z dolgodelujoče injekcije risperidona
Switching from the 300 units/ml to the 100 units/ml concentration results in an increased risk of hypoglycaemic events, mainly in the first week after the switch.
Prehod s koncentracije 300 enot/ml na 100 enot/ml poveča tveganje za hipoglikemije, predvsem v prvem tednu po prehodu.
Switching from TREVICTA to 1-monthly paliperidone palmitate injectable
Prehod z zdravila TREVICTA na 1-mesečne injekcije paliperidonijevega palmitata
Switching from TREVICTA to oral daily paliperidone prolonged release tablets
Prehod z zdravila TREVICTA na peroralni paliperidon v obliki tablet s podaljšanim sproščanjem enkrat na dan
Switching from TREVICTA to other antipsychotic medicinal products
Prehod z zdravila TREVICTA na drugo antipsihotično zdravilo
Switching from twice-daily basal insulins to once-daily Toujeo, the recommended initial Toujeo dose is 80% of the total daily dose of basal insulin that is being discontinued.
Pri prehodu z bazalnih insulinov dvakrat na dan na zdravilo Toujeo enkrat na dan je priporočeni začetni odmerek zdravila Toujeo 80 % celotnega dnevnega odmerka bazalnega insulina, ki ga je bolnik uporabljal dotlej.
Switching from vitamin K antagonist (VKA) therapy to Eliquis
Prehod z zdravljenja z antagonistom vitamina K (AVK) na zdravilo Eliquis
Switching patients from exenatide to liraglutide after 26 weeks of treatment resulted in an additional and statistically significant reduction in HbA1c (­0.32%, 95% CI: ­0.41 to ­0.24) at week 40, but a formal control group was not available.
Prehod bolnikov z eksenatida na liraglutid po 26 tednih zdravljenja je povzročil dodatno in statistično značilno znižanje HbA1c (-0,32 %, 95 % IZ: - 0,41 do -0,24) v 40. tednu, vendar pa formalne kontrolne skupine ni bilo.
Switching patients from sitagliptin to liraglutide after 52 weeks of treatment resulted in additional and statistically significant reduction in HbA1c (­0.24% and ­0.45%, 95% CI: ­0.41 to ­0.07 and ­0.67 to ­0.23 ) at week 78, but a formal control group was not available.
Prehod bolnikov s sitagliptina na liraglutid po 52 tednih zdravljenja je povzročil dodatno in statistično značilno znižanje HbA1c (-0,24 % in -0,45 %, 95 % IZ: -0,41 do -0,07 in -0,67 do -0,23) v 78. tednu, vendar pa formalne kontrolne skupine ni bilo.
Switching therapy from SSRI/SNRI antidepressant to agomelatine
Menjava zdravljenja s SSRI/SNRI na agomelatin
Switching to and from Lixiana
Zamenjava zdravila Lixiana z drugim zdravilom in obratno
Switching to Eviplera was non-inferior in maintaining HIV-1 RNA < 50 copies/mL when compared to patients who stayed on a ritonavir-boosted protease inhibitor in combination with two NRTIs [Treatment difference (95% CI): + 3.8% (-1.6% to 9.1%)].
Prehod na zdravilo Eviplera ni bil slabši pri ohranjanju HIV-1 RNA < 50 kopij/ml v primerjavi z bolniki, ki so ostali na zdravljenju z zaviralcem proteaze, okrepljenim z ritonavirjem, v kombinaciji z dvema NRTI [razlika zdravljenja (95-% IZ): + 3,8 % (-1,6 % do 9,1 %)].
Switching to Lixiana
Zamenjava drugega antikoagulanta z zdravilom Lixiana
Switching to other antipsychotic medicinal products
Prehod na druga antipsihotična zdravila
Switching to other antipsychotic medicinal products
Prehod na drugo antipsihotično zdravilo
Switching to REYATAZ capsules from REYATAZ oral powder is encouraged as soon as patients are able to consistently swallow capsules.
Prehod z zdravljenja z zdravilom REYATAZ v obliki peroralnega praška na zdravljenje z zdravilom REYATAZ v obliki kapsul je priporočljiv takoj, ko lahko bolniki kapsule zanesljivo pogoltnejo.
Switzerland Name and address of the manufacturer responsible for batch release
Ime in naslov izdelovalca, odgovornega za sproščanje serij
Switzerland Name and address of the manufacturer responsible for batch release
Švica Ime in naslov izdelovalca, odgovornega za sproščanje serij
Swollen ankles, feet or hands, loss of appetite, passing less urine, or abnormal blood test results, which may be symptoms of kidney problems or kidney failure
Oteklost gležnjev, stopal ali dlani, izguba teka, izločanje manj urina ali nenormalni izvidi preiskav krvi; to so lahko simptomi težav z ledvicami ali odpovedi ledvic.
Swollen eye lids, red eyes, dry eye, difficulty focusing on close objects, ringing in ears
otekle očesne veke, rdeče oči, suho oko, težave pri osredotočanju na predmete v bližini, zvonjenje v ušesih;
Swollen eyelids
otečene veke,
Swollen face, drug eruption
otekanje obraza, kožne spremembe zaradi jemanja zdravil
Swollen face, drug eruption,
otekanje obraza, kožne spremembe zaradi jemanja zdravil
Swollen face, hands, feet
oteklost obraza, dlani in stopal
Swollen face, hands, feet;
oteklost obraza, dlani in stopal;
Swollen face, tongue or pharynx
otekel obraz, jezik ali žrelo
Swollen face, tongue, mouth or throat, difficulty in breathing and swallowing, hives, wheezing, burning and stinging where the infusion was given, chills, flushing, skin rash over the whole body, headache, fall in blood pressure, restlessness, faster heart beat, tightness of the chest (including chest pain and chest discomfort), back pain, tiredness (lethargy), nausea, vomiting, tingling.
Otekanje obraza, jezika, ustnic ali grla, težave pri dihanju in požiranju, koprivnica, sopenje, pekoč občutek in zbadanje na mestu injiciranja ali infundiranja, mrazenje, rdečico, kožni izpuščaj po celem telesu, glavobol, padec krvnega tlaka, nemir, pospešen srčni utrip, tiščanje v prsih (vključno z bolečino v prsih in nelagodjem v prsih), bolečino v hrbtu, utrujenost (letargijo), slabost, bruhanje, mravljinčenje.
Swollen glands
otekle bezgavke,
Swollen glands (lymph nodes), agitation, tremor, abnormal dream, excessive muscle activity, depersonalisation (not feeling like yourself), medicine dependence, amnesia (memory disturbance), loss of interest, exaggerated feeling of well being, convulsion (fits), speech disorder, small pupil size, difficulty urinating, eye inflammation or infection, rapid or slow heart beat, low blood pressure, palpitations, myocardial infarction (heart attack), chest tightness, shortness of breath, asthma, yawning, pain and sores in mouth, tongue discolouration, acne, skin nodule, hair loss, dry or scaling skin, inflammation of joints, urinary tract infection, abnormal blood tests, blood in urine, abnormal ejaculation, menstrual or vaginal problems, kidney stone, protein in your urine, painful or difficult urination, sensitivity to heat or cold, heat stroke, loss of appetite feelings of hostility.
Otekle žleze (bezgavke), razburjenost, tresenje, nenormalne sanje, čezmerna mišična aktivnost, depersonalizacija (bolnik se ne počuti pri sebi), odvisnost od zdravila, amnezija (motnje spomina), izguba zanimanja, pretiran občutek dobrega počutja, epileptični krči (napadi), motnje govora, majhne zenice, težave z uriniranjem, vnetje ali okužba oči, hitro ali počasno utripanje srca, nizek krvni tlak, palpitacije, miokardni infarkt (srčna kap), občutek tiščanja v prsih, zasoplost, astma, zehanje, bolečina in razjede v ustih, obarvanje jezika, akne, kožni vozliči, izguba las, suha koža ali luščenje kože, vnetje sklepov, okužba sečil, nenormalni izvidi krvnih testov, kri v urinu, nenormalna ejakulacija, menstrualne ali vaginalne težave, ledvični kamni, beljakovine v urinu, boleče uriniranje ali težave pri uriniranju, občutljivost na toplo ali mrzlo, vročinska kap, izguba teka, občutek sovražnosti.
Swollen glands (lymph nodes), agitation, tremor, abnormal dream, excessive muscle activity, depersonalisation (not feeling like yourself), medicine dependence, amnesia (memory disturbance), loss of interest, exaggerated feeling of well being, convulsion (fits), speech disorder, small pupil size, difficulty urinating, eye inflammation or infection, rapid or slow heart beat, low blood pressure, palpitations, myocardial infarction (heart attack), chest tightness, shortness of breath, asthma, yawning, pain and sores in mouth, tongue discolouration, acne, skin nodule, hair loss, dry or scaling skin, inflammation of joints, urinary tract infection, abnormal blood tests, blood in urine, abnormal ejaculation, menstrual or vaginal problems, kidney stone, protein in your urine, painful or difficult urination, sensitivity to heat or cold, heat stroke, loss of appetite, feelings of hostility.
Otekle žleze (bezgavke), razburjenost, tresenje, nenormalne sanje, čezmerna mišična aktivnost, depersonalizacija (bolnik se ne počuti pri sebi), odvisnost od zdravila, amnezija (motnje spomina), izguba zanimanja, pretiran občutek dobrega počutja, epileptični krči (napadi), motnje govora, majhne zenice, težave z uriniranjem, vnetje ali okužba oči, hitro ali počasno utripanje srca, nizek krvni tlak, palpitacije, miokardni infarkt (srčna kap), občutek tiščanja v prsih, zasoplost, astma, zehanje, bolečina in razjede v ustih, obarvanje jezika, akne, kožni vozliči, izguba las, suha koža ali luščenje kože, vnetje sklepov, okužba sečil, nenormalni izvidi krvnih testov, kri v urinu, nenormalna ejakulacija, menstrualne ali vaginalne težave, ledvični kamni, beljakovine v urinu, boleče uriniranje ali težave pri uriniranju, občutljivost na toplo ali mrzlo, vročinska kap, izguba teka, občutek sovražnosti.
Swollen glands in the axilla
otekle podpazdušne bezgavke
Swollen glands in the neck armpit or groin (lymphadenopathy)
povečane bezgavke na vratu, pod pazduho ali v dimljah (limfadenopatija),
Swollen glands in the neck, armpit or groin
otekle bezgavke na vratu, pod pazduhami ali v dimljah,
Swollen glands in the neck, armpit or groin (lymphadenopathy)
otekle bezgavke na vratu, pod pazduho ali v dimljah (limfadenopatija);
Swollen glands in your neck
otekle vratne bezgavke,
Swollen lymph nodes
otekle bezgavke
Swollen lymph nodes
otekle bezgavke,
Swollen lymph nodes.
otekle bezgavke
Swollen or enlarged lymph nodes
zatečene ali povečane bezgavke
Swollen or puffy hands or feet
Otekle ali zabuhle roke ali noge.
Swollen tongue
otečen jezik
Swollen, bleeding gums, signs of gum inflammation (gingivitis)
občutljive, krvaveče dlesni, znaki vnetja dlesni (gingivitis)
Sy
Sim
Sycrest is not recommended for use in patients below the age of 18 years.
Uporabe zdravila Sycrest ne priporočamo pri bolnikih, mlajših od 18 let.
SYLVANT 100 mg powder for concentrate for solution for infusion
SYLVANT 100 mg prašek za koncentrat za raztopino za infundiranje
SYLVANT 100 mg powder for concentrate for solution for infusion siltuximab
SYLVANT 100 mg prašek za koncentrat za raztopino za infundiranje
SYLVANT 400 mg powder for concentrate for solution for infusion
SYLVANT 400 mg prašek za koncentrat za raztopino za infundiranje
SYLVANT 400 mg powder for concentrate for solution for infusion EU/1/14/928/002
SYLVANT 400 mg prašek za koncentrat za raztopino za infundiranje EU/1/14/928/002
SYLVANT 400 mg powder for concentrate for solution for infusion siltuximab
SYLVANT 400 mg prašek za koncentrat za raztopino za infundiranje
Sylvant can only be obtained with a prescription and treatment should be given by qualified healthcare professionals and under appropriate medical supervision.
Izdaja zdravila Sylvant je le na recept, zdravilo pa lahko dajejo samo usposobljeni zdravstveni delavci, pri čemer mora biti zagotovljen ustrezen zdravniški nadzor.
Sylvant has been investigated in one main study involving 79 adults with multicentric Castleman’s disease who tested negative for HIV and HHV-8.
Zdravilo Sylvant so proučevali v eni glavni študiji, v katero so vključili 79 odraslih z multicentrično Castlemanovo boleznijo, pri katerih so bili izidi preiskav za HIV in HHV-8 negativni.
Sylvant is a medicine that contains the active substance siltuximab.
Sylvant je zdravilo, ki vsebuje zdravilno učinkovino siltuksimab.
Sylvant is available as a powder to be made into a solution for infusion (drip) into a vein.
Zdravilo Sylvant je na voljo v obliki praška za pripravo raztopine za infundiranje (kapalno infuzijo) v veno.
SYLVANT is available in packs containing 1 vial.
Zdravilo SYLVANT je na voljo v pakiranjih, ki vsebujejo 1 vialo.
SYLVANT is indicated for the treatment of adult patients with multicentric Castleman’s disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative.
Zdravilo SYLVANT je indicirano za zdravljenje odraslih bolnikov z multicentrično Castlemanovo boleznijo (MCD - multicentric Castleman’s disease), ki niso okuženi z virusom humane imunske pomanjkljivosti (so HIV negativni) in niso okuženi s humanim herpesvirusom-8 (so HHV-8 negativni).
SYLVANT is not recommended for use during pregnancy.
Uporaba zdravila SYLVANT v nosečnosti ni priporočena.
Sylvant is produced by a method known as ‘recombinant DNA technology’; it is made by cells that have received a gene (DNA), which makes them able to produce siltuximab.
Zdravilo Sylvant se pridobiva z metodo, imenovano „tehnologija rekombinantne DNA“: izdelajo ga celice, v katere so vstavili gen (DNA), s pomočjo katerega lahko tvorijo siltuksimab.
SYLVANT is supplied as a glass vial containing a white powder for concentrate for solution for infusion.
Zdravilo SYLVANT je na voljo v stekleni viali, ki vsebuje bel prašek za pripravo koncentrata za raztopino za infundiranje.
SYLVANT is used to treat multicentric Castleman’s disease (MCD) in adult patients who do not have human immunodeficiency virus (HIV) or human herpesvirus-8 (HHV-8) infection.
Zdravilo SYLVANT uporabljamo za zdravljenje multicentrične Castlemanove bolezni pri odraslih bolnikih, ki niso okuženi z virusom humane imunske pomanjkljivosti (virusom HIV) ali s humanim herpesvirusom-8 (virusom HHV-8).
Sylvant was more effective than placebo in reducing tumour size and disease symptoms: 17 out of 53 patients who received Sylvant showed a partial response and one showed a complete response, compared with none of the 26 patients who received placebo.
Zdravilo Sylvant je bilo učinkovitejše od placeba pri zmanjšanju velikosti tumorjev in simptomov bolezni: pri 17 od 53 bolnikov, ki so prejemali zdravilo Sylvant, so opazili delni odziv, in pri enem popolni odziv, medtem ko se v skupini s placebom ni odzval nobeden od 26 bolnikov.