natgillin/translations-raw huggingface dataset:
Caution is advised when bisphosphonates are administered with aminoglycosides, calcitonin or loop diuretics since these agents may have an additive effect, resulting in a lower serum calcium level for longer periods than required (see section 4.4).
Kadar difosfonate dajemo sočasno z aminoglikozidi, kalcitoninom ali diuretiki Henlejeve zanke, je priporočljiva previdnost, ker utegnejo imeti navedene učinkovine aditiven učinek, kar bi imelo za posledico nižje koncentracije serumskega kalcija za dalj časa, kot je potrebno (glejte poglavje 4.4).
Caution is advised when bisphosphonates are administered with aminoglycosides, calcitonin or loop diuretics since these agents may have an additive effect, resulting in a lower serum calcium level for longer periods than required (see section 4.4).
Kadar difosfonate dajemo sočasno z aminoglikozidi, kalcitoninom ali diuretiki Henleyeve zanke je priporočljiva previdnost, ker utegnejo imeti navedene učinkovine aditiven učinek, kar bi imelo za posledico nižje koncentracije serumskega kalcija za dalj časa, kot je potrebno (glejte poglavje 4.4).
Caution is advised when bisphosphonates are administered with aminoglycosides, calcitonin or loop diuretics, since these agents may have an additive effect, resulting in a lower serum calcium level for longer periods than required (see section 4.4).
Kadar difosfonate dajemo sočasno z aminoglikozidi, kalcitoninom ali diuretiki Henlejeve zanje, je priporočljiva previdnost, ker utegnejo imeti navedene učinkovine aditiven učinek, kar bi imelo za posledico nižje koncentracije serumskega kalcija za dalj časa, kot je potrebno (glejte poglavje 4.4).
Caution is advised when bisphosphonates are administered with aminoglycosides, calcitonin or loop diuretics, since these agents may have an additive effect, resulting in a lower serum calcium level for longer periods than required (see section 4.4)..
Kadar difosfonate dajemo sočasno z aminoglikozidi, kalcitoninom ali diuretiki Henlejeve zanke je priporočljiva previdnost, ker utegnejo imeti navedene učinkovine aditiven učinek, kar bi imelo za posledico nižje koncentracije serumskega kalcija za dalj časa, kot je potrebno (glejte poglavje 4.4).
Caution is advised when bisphosphonates are administered with aminoglycosides, since both agents may have an additive effect, resulting in a lower serum calcium level for longer periods than required.
Kadar difosfonate dajemo sočasno z aminoglikozidi, je priporočljiva previdnost, ker utegneta imeti obe učinkovini aditiven učinek, kar bi imelo za posledico nižje koncentracije serumskega kalcija za dalj časa, kot je potrebno.
Caution is advised when co-administering with strong CYP 3A4 inhibitors (e.g. ketoconazole, ritonavir) as there is potential for increased systemic exposure to both fluticasone furoate and vilanterol, and concomitant use should be avoided.
Previdnost je potrebna med sočasno uporabo z močnimi zaviralci CYP3A4 (npr. ketokonazol, ritonavir), ker obstaja možnost večje sistemske izpostavljenosti flutikazonfuroatu in vilanterolu, sočasni uporabi se je treba izogniti.
Caution is advised when combining stiripentol with other substances that inhibit or induce one or more of these enzymes.
Svetujemo previdnost pri kombinaciji stiripentola z drugimi zdravili, ki zavirajo ali sprožajo enega ali več teh encimov.
Caution is advised when concomitantly using other medicinal products capable of lowering the seizure threshold [e.g. antidepressants (tricyclics, SSRIs, SNRIs), neuroleptics (phenothiazines, thioxanthenes and butyrophenones), mefloquine, bupropion, tramadol] (see section 4.4).
Previdnost je priporočljiva ob sočasni uporabi drugih zdravil, ki lahko znižujejo prag za pojav epileptičnih napadov [npr. antidepresivi (triciklični, SSRI, SNRI), nevroleptiki (fenotiazini, tioksanteni in butirofenoni), meflokin, bupropion in tramadol] (glejte poglavje 4.4).
Caution is advised when Effentora is coadministered with drugs that affect the serotoninergic neurotransmitter systems.
Pri sočasni uporabi zdravila Effentora z zdravili, ki vplivajo na sistem serotoninergičnih nevrotransmiterjev, je potrebna previdnost.
Caution is advised when initiating (or changing the dose of) concomitant systemic medicinal products (irrespective of pharmaceutical form) which may interact with α-adrenergic agonists or interfere with their activity i.e. agonists or antagonists of the adrenergic receptor (e.g. isoprenaline, prazosin).
Tudi pri uvedbi (ali spremembi odmerka) sočasnih sistemsko uporabljenih zdravil (ne glede na farmacevtsko obliko), ki lahko medsebojno delujejo z α-adrenergičnimi agonisti ali ovirajo njihovo delovanje, t.j. agonistov ali antagonistov adrenergičnih receptorjev (npr. izoprenalina, prazosina), je priporočljiva previdnost.
Caution is advised when Instanyl is coadministered with drugs that affect the serotoninergic neurotransmitter systems.
Pri sočasni uporabi zdravila Instanyl z zdravili, ki vplivajo na sistem serotoninergičnih nevrotransmiterjev, je potrebna previdnost.
Caution is advised when sildenafil is administered to patients taking an alpha-blocker, as the co- administration may lead to symptomatic hypotension in a few susceptible individuals (see section 4.5).
Previdnost je potrebna med uporabo sildenafila pri bolnikih, ki jemljejo antagoniste adrenergičnih receptorjev alfa, ker sočasna uporaba pri maloštevilnih občutljivih posameznikih lahko povzroči simptomatsko hipotenzijo (glejte poglavje 4.5).
Caution is advised when sildenafil is administered to patients taking an alpha-blocker, as the co-administration may lead to symptomatic hypotension in a few susceptible individuals (see section 4.5).
Previdnost je potrebna med uporabo sildenafila pri bolnikih, ki jemljejo antagoniste adrenergičnih receptrojev alfa, ker sočasna uporaba pri maloštevilnih občutljivih posameznikih lahko povzroči simptomatsko hipotenzijo (glejte poglavje 4.5).
Caution is advised when SonoVue is administered to patients with clinically significant pulmonary disease, including severe chronic obstructive pulmonary disease.
Svetujemo previdnost pri dajanju zdravila SonoVue bolnikom s klinično pomembnimi pljučnimi obolenji, vključno pri bolnikih s hudo kronično obstrukcijsko pljučno boleznijo.
Caution is advised when treating patients with a history of syncope receiving medicinal products known to be associated with hypotension; or who are dehydrated due to recurrent diarrhoea or vomiting.
Pri zdravljenju bolnikov s sinkopami v anamnezi, ki prejemajo zdravila, za katera je znano, da so povezana s pojavom hipotenzije, ali pri tistih, ki so dehidrirani zaradi ponavljajoče se driske ali bruhanja, svetujemo previdnost.
Caution is advised when TRISENOX is coadministered with other medicinal products known to cause QT/QTc interval prolongation such as macrolide antibiotics, the antipsychotic thioridazine, or medicinal products known to cause hypokalemia or hypomagnesaemia.
Pri skupni uporabi zdravila TRISENOX in drugih zdravil, za katere je znano, da povzročajo podaljšanje intervala Q-T/Q- Tc, kot so makrolidni antibiotiki, antipsihotik tioridazin ali zdravila, za katera je znano, da povzročajo hipokaliemijo ali hipomagneziemijo, svetujemo previdnost.
Caution is advised when using medicinal products such as antihypertensives and/or cardiac glycosides concomitantly with SIMBRINZA or in patients with severe or unstable and uncontrolled cardiovascular disease (see section 4.5)
Pri sočasni uporabi zdravila SIMBRINZA z zdravili, kot so antihipertenzivi in/ali kardiotonični glikozidi, ter pri bolnikih s hudo ali nestabilno in nenadzorovano srčnožilno boleznijo je potrebna previdnost (glejte poglavje 4.5).
Caution is advised when using Onduarp in such patients as amlodipine and telmisartan are not dialysable (see also section 4.4).
Zdravilo Onduarp je treba pri teh bolnikih uporabljati previdno, ker se amlodipin in telmisartan med dializo ne odstranita (glejte tudi poglavje 4.4).
Caution is advised when Zoledronic Acid Hospira is administered with anti-angiogenic medicinal products as an increase in the incidence of ONJ has been observed in patients treated concomitantly with these medicinal products.
Pri uporabi zoledronsko kislino skupaj z antiangiogenimi zdravili je potrebna previdnost, saj so pri bolnikih, ki so sočasno prejemali navedena zdravila, opažali povečano pogostnost osteonekroze čeljustnic.
Caution is advised when Zoledronic Acid Hospira is administered with anti-angiogenic medicinal products, as an increase in the incidence of ONJ has been observed in patients treated concomitantly with these medicinal products.
Pri uporabi zoledronsko kislino skupaj z antiangiogenimi zdravili je potrebna previdnost, saj so pri bolnikih, ki so sočasno prejemali navedena zdravila, opažali povečano pogostnost osteonekroze čeljustnic.
Caution is advised when zoledronic acid is administered with anti-angiogenic medicinal products as an increase in the incidence of ONJ has been observed in patients treated concomitantly with these medicinal products.
Pri uporabi zdravila Zoledronska kislina Mylan skupaj z antiangiogenimi zdravili je potrebna previdnost, saj so pri bolnikih, ki so sočasno prejemali navedena zdravila, opažali povečano pogostnost osteonekroze čeljusti.
Caution is advised when Zoledronic acid is administered with medicinal products known to cause hypocalcaemia, as they may have a synergistic effect resulting in severe hypocalcaemia (see section 4.5).
Pri dajanju zoledronske kisline skupaj z zdravili, za katera je znano, da povzročajo hipokalciemijo, je potrebna previdnost, saj lahko delujejo sinergistično in povzročijo hudo hipokalciemijo (glejte poglavje 4.5).
Caution is advised when Zoledronic acid Teva is administered with anti-angiogenic medicinal products as an increase in the incidence of ONJ has been observed in patients treated concomitantly with these medicinal products.
Pri uporabi zdravila Zoledronska kislina Teva skupaj z antiangiogenimi zdravili je potrebna previdnost, saj so pri bolnikih, ki so sočasno prejemali navedena zdravila, opažali povečano pogostnost osteonekroze čeljustnic.
Caution is advised when Zoledronic acid Teva is administered with medicinal products known to cause hypocalcaemia, as they may have a synergistic effect resulting in severe hypocalcaemia (see section 4.5).
Pri dajanju zdravila Zoledronska kislina Teva skupaj z zdravili, za katera je znano, da povzročajo hipokalciemijo, je potrebna previdnost, saj lahko delujejo sinergistično in povzročijo hudo hipokalciemijo (glejte poglavje 4.5).
Caution is advised when Zometa is administered with anti-angiogenic medicinal products as an increase in the incidence of ONJ has been observed in patients treated concomitantly with these medicinal products.
Pri uporabi zdravila Zometa skupaj z antiangiogenimi zdravili je potrebna previdnost, saj so pri bolnikih, ki so sočasno prejemali navedena zdravila, opažali povečano pogostnost osteonekroze čeljustnic.
Caution is advised with treatment of patients most at risk of developing a gastrointestinal complication with NSAIDs: the elderly, patients using any other NSAID or acetylsalicylic acid concomitantly or patients with a prior history of gastrointestinal disease, such as ulceration and GI bleeding.
Previdnost je priporočljiva pri zdravljenju bolnikov, pri katerih obstaja največja možnost za pojav zapletov na prebavilih, povzročenih z NSAID: starejši, bolniki, ki sočasno uporabljajo katerikoli drugo NSAID ali acetilsalicilno kislino, in bolniki s predhodno anamnezo gastrointestinalnih obolenj, kot so ulkusi ali krvavitve v prebavilih.
Caution is advised.
Svetujemo previdnost.
Caution is also advised if mirabegron is co-administered with CYP2D6 substrates that are individually dose titrated.
Previdnost je potrebna tudi, če je mirabegron uporabljen sočasno s substrati CYP2D6, katerih odmerek je individualno titriran.
Caution is also needed when Atripla is taken at the same time as other medicines.
Prav tako je potrebna previdnost pri sočasnem jemanju zdravila Atripla z drugimi zdravili.
Caution is also needed when Stocrin is taken at the same time as other medicines.
Previdnost je potrebna tudi pri jemanju zdravila Stocrin sočasno z drugimi zdravili.
Caution is also needed when Sustiva is taken at the same time as other medicines.
Previdnost je potrebna tudi pri jemanju zdravila Sustiva sočasno z drugimi zdravili.
Caution is indicated when zoledronic acid is used with other potentially nephrotoxic drugs.
Kadar zoledronsko kislino dajemo z drugimi potencialno nefrotoksičnimi zdravili, je potrebna previdnost.
Caution is needed if Corlentor is taken with some other medicines.
Pri jemanju zdravila Corlentor z nekaterimi drugimi zdravili je potrebna previdnost.
Caution is needed if Ivabradine Anpharm is taken with some other medicines.
Pri jemanju zdravila Ivabradine Anpharm z nekaterimi drugimi zdravili je potrebna previdnost.
Caution is needed if Procoralan is taken with some other medicines.
Pri jemanju zdravila Procoralan z nekaterimi drugimi zdravili je potrebna previdnost.
Caution is needed if you are hypersensitive to tetracycline.
Previdnost je potrebna, če ste alergični na tetracikline.
Caution is needed in elderly patients ≥75 years with multiple co-morbidities (see sections 4.2 and 5.1).
Previdnost je potrebna pri starejših bolnikih (≥ 75 let) z več sočasnimi boleznimi (glejte poglavji 4.2 in 5.1).
Caution is needed in patients with coronary artery disease.
Pri bolnikih z boleznijo koronarnih arterij je potrebna previdnost.
Caution is needed in patients ≥75 years old when co-morbidities are present (see sections 4.3, 4.4 and 5.1).
Previdnost je potrebna pri bolnikih, starih 75 let ali več, ki imajo sočasno še druge bolezni (glejte poglavja 4.3, 4.4 in 5.1).
Caution is needed when administering Revestive to persons with a known hypersensitivity to tetracycline.
Previdnost je potrebna pri dajanju zdravila Revestive osebam z znano preobčutljivostjo na tetracikline.
Caution is needed when administering this vaccine to persons with a known hypersensitivity (other than anaphylactic reaction) to the active substance, to any of the excipients and to trace residues e.g. formaldehyde, benzonase, or sucrose.
Pri cepljenju oseb z znano preobčutljivostjo (poleg anafilaktične reakcije) na zdravilno učinkovino, katerokoli pomožno snov ali ostanke v sledeh, npr. formaldehid, Benzonaza ali saharozo, je treba biti previden.
Caution is needed when administering this vaccine to persons with a known hypersensitivity (other than anaphylactic reaction) to the active substance, to any of the excipients listed in section 6.1, to thiomersal and to residues (egg and chicken protein, ovalbumin, formaldehyde and sodium deoxycholate).
Previdnost je potrebna pri cepljenju oseb z znano preobčutljivostjo (poleg anafilaktične reakcije) za zdravilno učinkovino, katerokoli pomožno snov, navedeno v poglavju 6.1, tiomersal ali ostanke (jajčne in piščančje beljakovine, ovalbumin, formaldehid, in natrijev deoksiholat).
Caution is needed when administering this vaccine to persons with a known hypersensitivity (other than anaphylactic reaction) to the active substance, to any of the excipients listed in section 6.1, to thiomersal and to residues (egg and chicken protein, ovalbumin, formaldehyde, gentamicin sulphate and sodium deoxycholate).
Previdnost je potrebna pri cepljenju oseb z znano preobčutljivostjo (poleg anafilaktične reakcije) za zdravilno učinkovino, katerokoli pomožno snov, navedeno v poglavju 6.1, tiomersal ali zaostanke (jajčne ali piščančje proteine, ovalbumin, formaldehid, gentamicinijev sulfat ali natrijev deoksiholat).
Caution is needed when administrating this vaccine to persons with a known hypersensitivity (other than anaphylactic reaction) to the active substance(s), to any of the excipients and to trace residues e.g. formaldehyde, benzonase, or sucrose.
Pri cepljenju oseb z znano preobčutljivostjo (poleg anafilaktične reakcije) na zdravilno učinkovino, katerokoli pomožno snov ali ostanke v sledeh, npr. formaldehid, benzonazo ali saharozo, je treba biti previden.
Caution is needed when administrating this vaccine to persons with a known hypersensitivity (other than anaphylactic reaction) to the active substance, to any of the excipients listed in section 6.1 and to eggs, chicken proteins, kanamycin and neomycin sulphate, barium sulphate, formaldehyde and cetyltrimethylammonium bromide (CTAB).
Pri uporabi tega cepiva pri osebah z znano preobčutljivostjo (razen anafilaktičnih reakcij) na zdravilno učinkovino, katero koli pomožno snov, navedeno v poglavju 6.1, in na jajca, piščančje beljakovine, kanamicin in neomicinsulfat, barijev sulfat, formaldehid in cetiltrimetilamonijev bromid (CTAB) je treba biti previden.
Caution is needed when administrating this vaccine to persons with a known hypersensitivity (other than anaphylactic reaction) to the active substance, to any of the excipients listed in section 6.1, to thiomersal and to eggs, chicken proteins, kanamycin and neomycin sulphate, barium sulphate, formaldehyde and cetyltrimethylammonium bromide (CTAB).
Pri uporabi tega cepiva pri osebah z znano preobčutljivostjo (razen anafilaktičnih reakcij) na zdravilno učinkovino, katero koli pomožno snov, navedeno v poglavju 6.1, na tiomersal in na jajca, piščančje beljakovine, kanamicin in neomicinsulfat, barijev sulfat, formaldehid in cetiltrimetilamonijev bromid (CTAB) je treba biti previden.
Caution is needed when Cubicin is given to patients with kidney problems and the medicine may need to be given less often.
Previdnost je potrebna pri dajanju zdravila bolnikom, ki imajo težave z ledvicami, saj je morda treba zdravilo dajati manj pogosto.
Caution is needed when Invirase is taken at the same time as some other medicines.
Prav tako je potrebna previdnost pri sočasnem jemanju zdravila Invirase z drugimi zdravili.
Caution is recommended during concomitant use of Kuvan with all medicinal products that cause vasodilation, including those administered topically, by affecting nitric oxide (NO) metabolism or action including classical NO donors (e.g. glyceryl trinitrate (GTN), isosorbide dinitrate (ISDN), sodium nitroprusside (SNP), molsidomin), phosphodiesterase type 5 (PDE-5) inhibitors and minoxidil.
Previdnost je priporočljiva med sočasno uporabo zdravila Kuvan z vsemi zdravili, ki povzročajo vazodilatacijo, vključno s tistimi, ki se uporabljajo topikalno, tako, da vplivajo na presnovo ali delovanje dušikovega oksida (NO) vključno z klasičnimi donorji NO (npr. gliceriltrinitrat (GTN), izosorbid dinitrat (ISDN), natrijev nitroprusid (SNP), molsidomin), zaviralci fosfodiesteraze tipa 5 (PDE-5) in minoksidilom.
Caution is recommended in patients with epilepsy, former history of convulsions or patients with predisposing factors for epilepsy.
Previdnost je priporočljiva pri bolnikih z epilepsijo, s krči v anamnezi ali pri bolnikih z nagnjenostjo k epilepsiji.
Caution is recommended in patients with previous history of pancreatitis.
Pri bolnikih z anamnezo pankreatitisa se priporoča previdnost.
Caution is recommended in patients with severely impaired hepatic function.
Pri bolnikih s hudo okvaro delovanja jeter je potrebna previdnost.
Caution is recommended in thyroidectomy patients receiving levothyroxine and imatinib.
Zato je pri bolnikih po tiroidektomiji, ki prejemajo levotiroksin in imatinib, potrebna previdnost.
caution is recommended when
lumefantrina lahko povzroči
Caution is recommended when administering Iclusig to patients with hepatic impairment (see sections 4.2 and 5.2).
Pri dajanju zdravila Iclusig bolnikom z okvaro jeter se priporoča previdnost (glejte poglavji 4.2 in 5.2).
Caution is recommended when administering Iclusig to patients with hepatic impairment (see sections 4.4 and 5.2).
Pri dajanju zdravila Iclusig bolnikom z okvaro jeter se priporoča previdnost (glejte poglavji 4.4 in 5.2).
Caution is recommended when co-administering Senshio with fluconazole (see section 4.5).
Pri sočasni uporabi zdravila Senshio s flukonazolom je potrebna previdnost (glejte poglavje 4.5).
Caution is recommended when selecting anaesthetic agents.
Pri izbiri anestetika je priporočena previdnost.
Caution is recommended when using travoprost in aphakic patients, pseudophakic patients with a torn posterior lens capsule or anterior chamber lenses, or in patients with known risk factors for cystoid macular oedema.
Priporočamo previdnost pri uporabi travoprosta pri afakičnih bolnikih, psevdofakičnih bolnikih z raztrgano posteriorno lečno kapsulo ali z lečo v sprednjem prekatu ali pri bolnikih z znanimi dejavniki tveganja za cistoidni makularni edem.
Caution is recommended while using Kalydeco in patients with severe renal impairment (creatinine clearance less than or equal to 30 mL/min) or end-stage renal disease (see sections 4.4 and 5.2).
Previdnost je priporočljiva, kadar uporabljamo zdravilo Kalydeco pri bolnikih s težkimi okvarami ledvic (očistek kreatinina 30 ml/min ali manj) ali v končnem stadiju bolezni ledvic (glejte poglavji 4.4 in 5.2).
Caution is recommended while using lumacaftor/ivacaftor in patients with severe renal impairment or end-stage renal disease (see sections 4.2 and 5.2).
Pri uporabi lumakaftorja/ivakaftorja pri bolnikih s težko okvaro ledvic ali boleznijo ledvic v končnem stadiju je priporočljiva previdnost (glejte poglavji 4.2 in 5.2).
Caution is recommended while using Orkambi in patients with severe renal impairment (creatinine clearance less than or equal to 30 mL/min) or end-stage renal disease (see sections 4.4 and 5.2).
Previdnost je priporočljiva, kadar uporabljamo zdravilo Orkambi pri bolnikih s težkimi okvarami ledvic (očistek kreatinina 30 ml/min ali manj) ali v končnem stadiju bolezni ledvic (glejte poglavji 4.4 in 5.2).
Caution is recommended, particularly in those patients with severe hepatic impairment (see section 4.4).
Bodite previdni, zlasti pri bolnikih s hudo okvaro jeter (glejte poglavje 4.4).
Caution is required because ASA may inhibit the effect of uricosuric agents through competitive elimination of uric acid.
Potrebna je previdnost, kajti ASA lahko zavre učinek urikozuričnih zdravil s kompetitivno eliminacijo sečne kisline.
Caution is required in patients who are treated concomitantly with valproate or other GHB dehydrogenase inhibitors as pharmacokinetic and pharmacodynamic interactions have been observed when sodium oxybate is co-administered with valproate (see section 4.5).
Pri bolnikih, ki se sočasno zdravijo z valproatom ali drugimi zaviralci GHB dehidrogenaze je potrebna previdnost, saj so opazili farmakokinetične in farmakodinamične interakcije pri sočasni uporabi natrijevega oksibata in valproata (glejte poglavje 4.5).
Caution is required in treating patients whose underlying medical conditions might be compromised by increases in blood pressure, hypokalaemia (e.g., those on cardiac glycosides), or fluid retention (e.g., those with heart failure), severe or unstable angina pectoris, recent myocardial infarction or ventricular arrhythmia and those with severe renal impairment.
Previdnost je potrebna pri zdravljenju bolnikov, pri katerih lahko zvišan krvni tlak, hipokaliemija (na primer bolniki, ki jemljejo kardiotonične glikozide) ali zastajanje tekočin (na primer pri bolnikih s srčnim popuščanjem), huda ali nestabilna angina pektoris, nedaven miokardni infarkt ali ventrikularna aritmija poslabšajo njihovo osnovno bolezen in pri bolnikih s hudo ledvično okvaro.
Caution is required when Oncaspar is given in combination with other hepatotoxic substances, especially if there is pre-existing hepatic impairment.
Previdnost je potrebna, če zdravilo Oncaspar dajemo v kombinaciji z drugimi hepatotoksičnimi snovmi, zlasti v primeru obstoječe okvare jeter.
Caution is required when ONIVYDE is given in combination with other hepatotoxic medicinal products, especially in patients with pre-existing hepatic impairment.
Previdnost je potrebna, če zdravilo ONIVYDE dajemo v kombinaciji z drugimi hepatotoksičnimi snovmi, zlasti v primeru obstoječe okvare jeter.
Caution is required when using medicinal products that are human thymidine kinase substrates, e.g., zidovudine.
Previdnost je potrebna ob uporabi zdravil, ki so substrati humane timidin-kinaze, npr. zidovudin.