natgillin/translations-raw huggingface dataset:
Additionally, if after 6 hours, the heart rate is <45 bpm, or the ECG shows new onset second degree or higher grade AV block or a QTc interval ≥500 msec, extended monitoring (at least overnight monitoring), should be performed, and until the findings have resolved.
Tudi v primeru, da je srčna frekvenca po 6 urah še vedno nižja od 45 utripov na minuto ali posnetek EKG kaže, da je na novo prišlo do atrioventrikularnega bloka druge ali višje stopnje ali da traja interval QTc ≥500 msec, je treba spremljanje bolnika podaljšati (najmanj preko noči), dokler ugotovljene motnje ne izzvenijo.
Additionally, improvements compared to placebo were observed with tadalafil 40 mg in the physical functioning, role-physical, bodily pain, general health, vitality and social functioning domains of the SF-36.
Izboljšanje pri 40 mg tadalafilu v primerjavi s placebom se je pokazalo tudi v naslednjih domenah SF- 36: fizično delovanje, fizična vloga, telesna bolečina, splošno zdravstveno stanje, vitalnosti in socialna funkcija.
Additionally, in a clinical drug-drug interaction study with tenofovir alafenamide, which is more sensitive to intestinal P-gp inhibition, rilpivirine did not affect tenofovir alafenamide exposures when administered concurrently, indicating that rilpivirine is not a P-gp inhibitor in vivo.
Poleg tega v klinični študiji medsebojnega delovanja z alafenamidtenofoviratom, ki je bolj občutljiv na zaviranje črevesnega P-gp, rilpivirin ni vplival na izpostavljenost alafenamidtenofoviratu pri sočasnem dajanju, kar pomeni, da rilpivirin ni in vivo zaviralec P-gp.
Additionally, in a placebo-controlled clinical trial in patients receiving MEC, safety was evaluated for 504 patients receiving a single dose of IVEMEND 150 mg compared to 497 patients receiving the control regimen.
Poleg tega so v s placebom nadzorovanem kliničnem preskušanju pri bolnikih, ki so prejemali zmerno emetogeno kemoterapijo (MEC - Moderately Emetogenic Chemotherapy), ovrednotili varnost pri 504 bolnikih, ki so prejeli enkraten odmerek zdravila IVEMEND 150 mg, in pri 497 bolnikih, ki so prejeli kontrolno shemo zdravljenja.
Additionally, in a second study, treatment-experienced adults on a stable PI based highly active antiretroviral therapy (HAART) regimen were randomised to a once daily regimen containing emtricitabine or to continue with their PI-HAART regimen.
V drugi študiji se je pri odraslih, ki se zdravijo dalj časa s PI osnovanim visoko aktivnim stabilnim protiretrovirusnim režimom zdravljenja (HAART, highly active antiretroviral therapy), v nadaljevanju naključno porazdeljeno uporabilo ali kombinirano protiretrovirusno zdravljenje z emtricitabinom ali pa so nadaljevali s PI-HAART režimom.
Additionally, in an ad hoc analysis, 33% of patients receiving Esbriet showed a decline of ≥50 m in 6MWT distance, compared to 47% of patients receiving placebo in PIPF-006.
Poleg tega se je v ad hoc analizi v študiji PIPF–006 razdalja pri šestminutnem testu hoje pri 33 % bolnikov, ki so prejemali zdravilo Esbriet, zmanjšala za ≥ 50 m v primerjavi s 47 % tistih, ki so prejemali placebo.
Additionally, in the case of the 9 to 17 year olds pain at the injection site was very common.
Poleg tega so bile bolečine na mestu injiciranja pri otrocih in mladostnikih, starih od 9 do 17 let, zelo pogoste.
Additionally, individual case reports and in-vitro data suggest that either haemofiltration or haemodialysis (using high flux dialysis membranes with a cut-off point of 50,000 Dalton) may be useful in this situation.
Nadalje je iz posameznih prikazov primerov in in vitro podatkov razvidno, da je lahko v tem primeru koristna hemofiltracija ali hemodializa (ob uporabi visokopretočnih membran z mejno vrednostjo
Additionally, Ipreziv 80 mg resulted in significantly greater reductions in SBP than the highest approved doses of olmesartan medoxomil and valsartan.
Poleg tega je zdravilo Ipreziv 80 mg pokazalo pomembno večje znižanje sistoličnega krvnega tlaka (SKT) kot največji dovoljeni odmerki medoksomilolmesartanata in valsartana.
Additionally, it is recommended that HIV infected women do not breast-feed their infants in order to avoid transmission of HIV.
Dodatno je, z namenom preprečiti širjenje virusa, ravno tako priporočljivo, da matere, okužene z virusom HIV, otrok ne dojijo.
Additionally, lurasidone was superior to placebo on the predefined secondary endpoint Clinical Global Impression – Severity (CGI-S) scale.
Razen tega je bil lurasidon boljši od placeba tudi pri vnaprej opredeljenem sekundarnem opazovanem dogodku, lestvici CGI-S (Clinical Global Impression – Severity).
Additionally, Neoclarityn orodispersible tablet may be taken with or without a meal.
Zdravilo Neoclarityn orodisperzibilna tableta lahko jemljete s hrano ali brez nje.
Additionally, no clinically relevant adverse effects were observed following 7-day twice daily dosing of up to 800 µg aclidinium bromide in healthy subjects.
Poleg tega v naslednjih 7 dneh pri zdravih osebah, ki so dvakrat na dan prejele odmerek do 800 µg aklidinijevega bromida, niso opazili nobenih klinično pomembnih neželenih učinkov.
Additionally, other adverse events have been reported with post- marketing use of ProQuad and/or in clinical studies and post-marketing use of either the measles, mumps, and rubella vaccine manufactured by Merck & Co., Inc., the monovalent component vaccines of the measles, mumps, and rubella vaccine manufactured by Merck & Co., Inc., or Varicella Vaccine live (Oka/Merck).
Dodatno so na voljo podatki o neželenih učinkih iz obdobja trženja cepiva ProQuad in/ali iz kliničnih študij in iz obdobja trženja cepiva proti ošpicam, mumpsu in rdečkam izdelovalca Merck & Co., Inc., enovalentnih komponent cepiv proti ošpicam, mumpsu in rdečkam izdelovalca Merck & Co., Inc., in cepiva z živim virusom noric (Oka/Merck).
Additionally, other adverse reactions reported with post-marketing use of M-M-RVAXPRO and/or in clinical studies and post-marketing use of previous formulations of monovalent and of the combined measles, mumps, and rubella vaccines manufactured by Merck & Co., Inc. without regard to causality or frequency are available and are summarised in section b (frequency not known).
Dodatno so na voljo podatki o neželenih učinkih iz obdobja trženja cepiva M-M-RVAXPRO in/ali iz kliničnih študij in iz obdobja trženja prejšnjih oblik enovalentnih in kombiniranih cepiv proti ošpicam, mumpsu in rdečkam izdelovalca Merck & Co., Inc. in so ne glede na vzročnost ali pogostnost pojavljanja povzeti v poglavju b (pogostnost neznana).
Additionally, partial cytogenetic response (PCyR) was observed in 16% for a MCyR of 81%.
Poleg tega so zabeležili tudi delen citogenetični odziv (PCyR - partial cytogenetic response) pri 16 % bolnikov ob 81 % s pomembnim citogentičnim odzivom.
Additionally, partial cytogenetic response (PCyR) was observed in 16% for a MCyR of 81%.
Poleg tega so zabeležili tudi delen citogenetični odziv (PCyR – partial cytogenetic response) pri 16 % bolnikov ob 81 % s pomembnim citogenetičnim odzivom.
Additionally, patients have to drink 1-2 glasses of fluid before bedtime regardless of perceived thirst and replenish fluids overnight with each episode of nocturia.
Bolniki morajo dodatno spiti 1–2 kozarca tekočine, preden gredo spat, ne glede na to, ali so žejni, in si po vsaki epizodi nokturije ponovno napolniti tekočinske zaloge.
Additionally, patients treated with Viraferon and ribavirin combination therapy and zidovudine could be at increased risk of developing anaemia (low number of red blood cells).
kombinaciji z ribavirinom in zidovudinom, se lahko poveča verjetnost za razvoj anemije (majhno število rdečih krvnih celic).
Additionally, prescribers and pharmacists will be informed via a specific letter regarding the timelines for removing EXJADE dispersible tablets from the EU market.
Poleg tega morajo biti predpisovalci in farmacevti s posebnim dopisom obveščeni o rokih za umik disperzibilnih tablet zdravila EXJADE s trga Evropske skupnosti.
Additionally, pretreatment with antihistamines and/or antipyretics prior to LEMTRADA administration may also be considered.
Poleg tega pred dajanjem zdravila LEMTRADA pride v poštev tudi premedikacija z antihistaminiki in/ali antipiretiki.
Additionally, proliferative lesions were not observed in a 6-month chronic toxicity study in cynomolgus monkeys or in IL-6 deficient mice.
Poleg tega v 6- mesečni študiji kronične toksičnosti pri opicah cynomolgus in pri miših s pomanjkanjem IL-6 niso opazili proliferativnih lezij.
Additionally, ribavirin or Pegasys plus ribavirin combination therapy can be discontinued.
Lahko pa zdravljenje z ribavirinom ali kombinacijo zdravila Pegasys in ribavirina ukinemo.
Additionally, talk to your doctor, pharmacist or nurse before using EVRA if you have any of the following or they happen or get worse while using EVRA:
Dodatno se posvetujte se z zdravnikom, farmacevtom ali medicinsko sestro v primeru, da imate ali ste imeli katero koli izmed spodaj naštetih stanj, se le-ta pojavijo na novo ali pride do njihovega poslabšanja:
Additionally, the Committee considered that since Ravicti is available as a liquid this could make the medicine more palatable especially for children, compared with other medicines available as granules to be added to food; the liquid formulation also facilitates its administration via tube to patients unable to swallow because of neurological problems.
Poleg tega je Odbor menil, da bi bilo lahko zdravilo Ravicti, ker je na voljo v obliki tekočine, bolj všečno predvsem otrokom, v primerjavi z drugimi razpoložljivimi zdravili, kjer se zrnca dodajajo živilom; tekoča formulacija pa omogoča tudi dajanje prek cevke bolnikom, ki ne morejo požirati zaradi nevroloških težav.
Additionally, the company that markets Sylvant is required to set up a patient registry to provide further data on long-term safety.
Poleg tega mora družba, ki trži zdravilo Sylvant, vzpostaviti register bolnikov za pridobitev dodatnih podatkov o dolgoročni varnosti.
Additionally, the efficacy and safety of abacavir given once daily has been demonstrated in a pivotal clinical study (CNA30021- See section 5.1 Clinical experience).
Še več, učinkovitost in varnost takšne kombinacije, dane enkrat dnevno, je bila dokazana z osrednjo klinično študijo (CNA30021- Glejte poglavje 5.1 Klinične izkušnje).
Additionally, the following were reported during post-marketing experience with Pelzont and/or other nicotinic acid products (alone and/or with certain other cholesterol-lowering medicines). a sudden serious allergic reaction (anaphylactic shock).
Poleg tega so v obdobju trženja zdravila Pelzont in/ali drugih zdravil z nikotinsko kislino (samostojno in/ali skupaj z določenimi drugimi zdravili za zniževanje ravni holesterola) poročali o: nenadni resni alergijski reakciji (anafilaktičnem šoku).
Additionally, the following were reported during post-marketing experience with Tredaptive and/or other nicotinic acid products (alone and/or with certain other cholesterol-lowering medicines): a sudden serious allergic reaction (anaphylactic shock).
Poleg tega so v obdobju trženja zdravila Tredaptive in/ali drugih zdravil z nikotinsko kislino (samostojno in/ali skupaj z določenimi drugimi zdravili za zniževanje ravni holesterola) poročali o: nenadni resni alergijski reakciji (anafilaktičnem šoku).
Additionally, the following were reported during post-marketing experience with Trevaclyn and/or other nicotinic acid products (alone and/or with certain other cholesterol-lowering medicines). a sudden serious allergic reaction (anaphylactic shock).
Poleg tega so v obdobju trženja zdravila Trevaclyn in/ali drugih zdravil z nikotinsko kislino (samostojno in/ali skupaj z določenimi drugimi zdravili za zniževanje ravni holesterola) poročali o nenadni resni alergijski reakciji (anafilaktičnem šoku).
Additionally, the geometric mean plasma AUCinf of free (non-liposome associated) MTP-PE in mild and moderate hepatic impairment were 47% higher than the corresponding values in the matched normal hepatic function groups.
Razen tega pa je bila pri blagi in zmerni okvari jeter geometrijska srednja vrednost AUCinf prostega (nevezanega na liposome) MTP-PE v plazmi za 47 % večja od ustreznih vrednosti pri primerljivih skupinah z normalnim delovanjem jeter.
Additionally, the observed incidence of antibody (including inhibitory antibody) positivity in an assay may be influenced by several factors including assay methodology, sample handling, timing of sample collection, concomitant medications, and underlying disease.
Poleg tega na ugotovljeno pojavnost pozitivnosti testa za protitelesa (vključno z zaviralnimi protitelesi) lahko vpliva več dejavnikov, vključno z metodologijo testa, postopki ravnanja z vzorci, časom odvzema vzorca, sočasno uporabljenimi zdravili in osnovno boleznijo.
Additionally, the overall number of deaths occurring in field conditions amongst piglets born to vaccinated sows and gilts was investigated and compared with those born to unvaccinated mothers.
Poleg tega so spremljali in primerjali celokupno smrtnost pri naravnih pogojih med pujski, ki so jih povrgle cepljene svinje in mladice, in pujski necepljenih samic.
Additionally, the pack contains:
Škatla vsebuje dodatno še:
Additionally, the proportion of patients who were composite responders to eluxadoline at each 4-week interval for months 1 through 6 was higher than placebo for both doses in both Phase 3 studies demonstrating that efficacy is maintained with continuous eluxadoline treatment.
Poleg tega je bil delež bolnikov, ki so dosegli sestavljeni odziv na eluksadolin v vsakem 4-tedenskem intervalu od 1. do 6. meseca, večji od placeba pri obeh odmerkih v obeh študijah faze 3, kar dokazuje, da se učinkovitost ohrani med nadaljevanjem zdravljenja z eluksadolinom.
Additionally, the systemic exposures (AUCinf) of free (non-liposome associated) MTP-PE in mild or moderate renal insufficiency were similar to those observed in healthy adult subjects with normal renal function.
Tudi sistemska izpostavljenost (AUCinf) prostemu (nevezanemu na liposome) MTP-PE je bila pri odraslih prostovoljcih z blago ali zmerno ledvično insuficienco podobna kot pri zdravih odraslih osebah z normalnim delovanjem ledvic.
Additionally, there have been very rare reports of peripheral demyelinating polyneuropathies (including Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, demyelinating polyneuropathy, and multifocal motor neuropathy).
Poleg tega so zelo redko poročali o perifernih demielinizirajočih polinevropatijah (vključno z Guillain-Barréjevim sindromom, kronično vnetno demielinizirajočo polinevropatijo, demielinizirajočo polinevropatijo in multifokalno motorično nevropatijo).
Additionally, there is substantial number of events that are timely related to the initiation of treatment with agomelatine and with positive dechallenge.
Obstaja tudi precejšnje število dogodkov, ki so časovno povezani z začetkom zdravljenja z agomelatinom in z delnim ali popolnim izginotjem neželenega učinka po prekinitvi zdravljenja z zdravilom.
Additionally, trastuzumab is a potent mediator of antibody-dependent cell-mediated cytotoxicity (ADCC).
Trastuzumab je tudi močan mediator od protiteles odvisne celične citotoksičnosti (antibody-dependent cell-mediated cytotoxicity – ADCC).
Additionally, TSH elevations were reported in 4 cytokine-refractory MRCC patients (2%).
Poleg tega so pri 4 bolnikih (2 %) z MRCC, odpornemu proti citokinom, zabeležili zvečanje TSH.
Additionally, Vogt-Koyanagi-Harada syndrome (an autoimmune inflammatory disorder affecting the eyes, skin and the membranes of the ears, brain and spinal cord), thoughts about threatening the life of others, mania (excessive or unreasonable enthusiasm), bipolar disorders (mood disorders characterized by alternating episodes of sadness and excitement), congestive heart failure, pericardial effusion (a fluid collection that develops between the pericardium (the lining of the heart) and the heart itself), and pulmonary fibrosis (scarring of the lungs) have been reported with IntronA use.
Poleg tega so pri uporabi zdravila IntronA poročali tudi o pojavu sindroma Vogt-Koyanagi-Harada (avtoimuna vnetna bolezen, ki prizadene oči, kožo in ušesne membrane ter možganske ovojnice in ovojnice hrbtenjače), o pojavu misli, kako ogroziti življenje drugih, maniji (čezmerno ali nesmiselno navdušenje), bipolarnih motnjah (motnje razpoloženja, za katere je značilno izmenjevanje obdobij žalostnega razpoloženja z obdobji navdušenosti), kongestivnem srčnem popuščanju, perikardnem izlivu (nabiranje tekočine med perikardom (srčno ovojnico) in samim srcem) in pljučni fibrozi (brazgotinjenje pljuč).
Additionally, your doctor needs to inspect your head, your neck, your mouth, your lymph glands and you will undergo CT scans regularly.
Vaš zdravnik vam mora pregledati glavo, vrat, usta, bezgavke in redno opravljati slikanje z računalniško tomografijo (CT).
Additionaly there have been post-marketing cases of dizziness, tremor, headache, somnolence, confusional state, hypertension, hallucinations and malaise.
Poleg tega je v času trženja zdravila prišlo do primerov omotičnosti, tremorja, glavobola, somnolence, stanja zmedenosti, hipertenzije, halucinacij in splošnega slabega počutja.
Additive activity or weak synergy with amikacin and levofloxacin has been seen for Pseudomonas aeruginosa and for gram-positive bacteria with daptomycin, linezolid, levofloxacin, and vancomycin.
Pri Pseudomonas aeruginosa so opazili aditivno delovanje ali šibko sinergistično delovanje z amikacinom in levofloksacinom, pri gram-pozitivnih bakterijah pa z daptomicinom, linezolidom, levofloksacinom in vankomicinom.
Addmedica, 101 rue Saint Lazare – 75009 Paris - France
Addmedica, 101 rue Saint Lazare – 75009 Pariz, Francija
Address: Forellenweg 16
Naslov: Forellenweg 16
Address: Sumneytown Pike – PO Box 4 – West Point – Pennsylvania 19486 Country: United States of America
Naslov: Sumneytown Pike – PO Box 4 – West Point – Pennsylvania 19486 Država: Združene države Amerike
Address: Waarderweg 39, 2031 BN Haarlem, P.O. Box 581, 2003 PC Haarlem Country: the Netherlands
Naslov: Waarderweg 39, 2031 BN Haarlem, P.O. Box 581, 2003 PC Haarlem Država: Nizozemska
adefovir (see section 5.1), this has not been confirmed in clinical trials and reduced efficacy is not expected.
Tega s kliničnimi preskušanji niso potrdili in zmanjšane učinkovitosti ni pričakovati.
Adefovir and Nevirapine Teva may be co-administered without dose adjustments.
Adefovir in zdravilo Nevirapin Teva lahko dajemo sočasno, brez prilagajanja odmerkov.
Adefovir diphosphate has an intracellular half-life of 12 to 36 hours in activated and resting lymphocytes.
Adefovir difosfat ima znotrajcelično razpolovno dobo od 12 do 36 ur v aktiviranih in mirujočih limfocitih.
Adefovir diphosphate selectively inhibits HBV DNA polymerases at concentrations 12-, 700-, and 10-fold lower than those needed to inhibit human DNA polymerases α, β, and γ, respectively.
Adefovir difosfat selektivno zavira HBV DNA-polimeraze pri koncentracijah, ki so 12, 700, in 10 krat nižje, kot so potrebne za zaviranje človeških DNA-polimeraz α, β in γ.
Adefovir dipivoxil
dipivoksiladefovirat
Adefovir dipivoxil /tenofovir disoproxil
dipivoksiladefovirat/dizoproksil tenofovirat
Adefovir Dipivoxil 10 mg once daily
adefovir- dipivoksil 10 mg enkrat na dan
Adefovir dipivoxil 10 mg roll over to tenofovir disoproxil 245 mg (as fumarate) n = 125
10 mg dipivoksiladefovirata prehod na 245 mg dizoproksiltenofovirata (v obliki dizoproksiltenofovirijevega fumarata) n = 125
Adefovir dipivoxil 10 mg roll over to tenofovir disoproxil 245 mg (as fumarate) n = 90
10 mg dipivoksiladefovirata prehod na 245 mg dizoproksiltenofovirata (v obliki dizoproksiltenofovirijevega fumarata) n = 90
Adefovir dipivoxil and Emtricitabine/Tenofovir disoproxil Zentiva should not be administered concomitantly (see section 4.4).
Dipivoksiladefovirat in zdravilo Emtricitabin/dizoproksiltenof ovirat Zentiva se ne sme uporabljati sočasno (glejte poglavje 4.4).
Adefovir dipivoxil should not be administered concurrently with tenofovir disoproxil fumarate (Viread).
Dipivoksiladefovirata se ne sme jemati sočasno s dizoproksiltenofoviratom fumaratom (Viread).
Adefovir dipivoxil:
dipivoksiladefovirat:
Adefovir is active against hepadnaviruses in vitro, including all common forms of lamivudine- resistant HBV (rtL180M, rtM204I, rtM204V, rtL180M/rtM204V), famciclovir-associated mutations (rtV173L, rtP177L, rtL180M, rtT184S or rtV207I) and hepatitis B immunoglobulin escape mutations (rtT128N and rtW153Q), and in in vivo animal models of hepadnavirus replication.
Adefovir in vitro deluje proti hepadnavirusom, vključujoč vse običajne oblike na lamivudin odpornih HBV (rtL180M, rtM204I, rtM204V, rtL180M/rtM204V), HBV z mutacijami povezanimi s famciklovirom (rtV173L, rtP177L, rtL180M, rtT184S ali rtV207I) in HBV z hepatitis B imunoglobulinu pobeglimi mutacijami (escape mutations) (rtT128N in rtW153Q) in v in vivo proti živalski obliki replikacije hepadnavirusa.
Adefovir is an antiviral belonging to the class ‘nucleoside analogues’.
Adefovir je protivirusno sredstvo, ki spada v razred „analogov nuklezoidov“.
Adefovir may be used in combination with lamivudine in lamivudine-refractory patients and in patients harbouring HBV with mutations at rtL180M and/or rtM204I/V. However, for patients harbouring HBV that contains the rtA181T mutation, consideration should be given to alternative treatment regimens due to the risk of reduced susceptibility to adefovir (see section 5.1).
Adefovir se lahko uporablja v kombinaciji z lamivudinom pri bolnikih, ki se ne odzivajo na zdravljenje z lamivudinom in pri bolnikih, ki so nosilci HBV z mutacijami na rtL180M in/ali rtM204I/V. Vendar je treba pomisliti na alternativni režim zdravljenja bolnikov, ki so nosilci HBV z mutacijo rtA181T zaradi tveganja za zmanjšano občutljivost za adefovir (glejte poglavje 5.1).