natgillin/translations-raw huggingface dataset:
Five times the recommended minimum dose applied at weekly intervals for 17 weeks was investigated in dogs aged over 6 months and tolerated with no evidence of adverse effects or undesirable clinical signs. 
Pri dajanju petkratnega priporočenega najnižjega odmerka v tedenskih intervalih, 17 tednov zapored pri psih, starejših od 6 mesecev, ni bilo stranskih učinkov ali neželenih kliničnih znakov.
In very rare cases the product may cause skin sensitisation or transient skin reactions (for example numbness, irritation or burning/tingling sensation). 
V redkih primerih lahko zdravilo pri občutljivi koži povzroči prehodne kožne reakcije (npr. odrevenelost, draženje ali pekoč občutek/mravljinčenje ).
Reduction of microfilariae (skin worm) (D. repens) 
Zmanjševanje okužbe z mikrofilarijami (kožna glista) (D.repens)
A single dose should be administered. 
Zadostuje enkratni odmerek zdravila.
A field study has shown that in heartworm positive dogs with microfilaraemia there is a risk of severe respiratory signs (coughing, tachypnea and dyspnea) that may require prompt veterinary treatment. 
velika možnost pojava resnih dihalnih znakov (kašelj, tahipneja, dispneja), ki zahtevajo takojšnje veterinarsko zdravljenje.
The treatment of cats weighing less than 1 kg and ferrets weighing less than 0.8 kg should be based on a benefit-risk assessment. 
Pri zdravljenju mačk, lažjih od 1 kg, in belih dihurjev, lažjih od 0,8 kg, je potrebno pred dajanjem oceniti razmerje korist/tveganje.
MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS Advocate for small cats and ferrets 
PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA MANJŠIH STIČNIH OVOJNINAH Advocate za male mačke in bele dihurje
Imidacloprid is effective against larval flea stages and adult fleas. 
Imidakloprid deluje na odrasle bolhe in njihove ličinke.
Oral administration of 10% of the recommended dose produced no adverse effects. 
Pri zaužitju 10 % terapevtskega odmerka ni bilo neželenih učinkov.
A single dose should be administered twice 4 weeks apart. 
Zdravilo dajemo v enkratnem odmerku dvakrat v enomesečnem presledku.
Excipients: 
Oprema:
After accidental oral ingestion or overdose, neurological signs (most of which are transient) such as ataxia, generalised tremors, ocular signs (dilated pupils, little pupillary reflex, nystagmus), abnormal respiration, salivation and vomiting may occur in very rare cases. 
Pri nenamernem zaužitju zdravila ali pri prekomernem odmerjanju se lahko v zelo redkih primerih pojavijo nevrološki znaki (večina jih je prehodnih) kot so ataksija, generaliziran tremor, očesni znaki (razširjene zenice, slab pupilarni refleks, očesni drget), nenormalno dihanje, slinjenje in bruhanje.
• the treatment of the lungworm Aelurostrongylus abstrusus (adults), 
• zdravljenje infestacije s pljučnim črvom Aelurostrongylus abstrusus (odrasli),
This product contains moxidectin (a macrocyclic lactone), therefore special care should be taken with Collie or Old English Sheep dogs and related breeds or crossbreeds, to correctly administer the product as described under section 4.9; in particular, oral uptake by the recipient and/or other animals in close contact should be prevented. 
Ker zdravilo vsebuje moksidektin (makrociklični lakton), moramo biti previdni pri nanosu zdravila koliju ali staroangleškim ovčarjem, njim sorodnim pasmam in njihovim mešancem kot je to opisano v odstavku 4.9.
The product may in very rare cases cause at the application site a sensation resulting in transient behavioural changes such as lethargy, agitation, and inappetence. 
V zelo redkih primerih lahko zdravilo preko mesta nanosa povzroči prehodne vedenjske spremembe: dremavost, vznemirjenje in neješčnost.
• the treatment of circulating microfilariae (Dirofilaria immitis), 
• zdravljenje mikrofilarij (Dirofilaria immitis),
Pack sizes: 0.4 ml, 1.0 ml, 2.5 ml and 4.0 ml per pipette; blister packs containing 1, 2, 3, 4, 6, 9, 12, 21 or 42 unit dose pipettes. 
merilne kapalke s po 0,4 ml, 1,0 ml, 2,5 ml in 4,0 ml pretisni omoti z 1, 2, 3, 4, 6, 9, 12, 21 in 42 merilnimi kapalkami (enotami odmerka)
The product may be administered throughout the year or at least 1 month before the first expected exposure to mosquitoes. 
Morda bomo morali zdravilo belemu dihurju dajati vse leto ali najmanj en mesec pred pričakovano izpostavljenostjo komarjem.
Benzyl alcohol Butylhydroxytoluene Propylene carbonate 
FARMACEVTSKI PODATKI 6.1 Seznam pomožnih snovi benzilalkohol butilhidroksitoluen propilen karbonat
If skin or eye symptoms persist, or the product is accidentally swallowed, seek medical advice immediately and show the package leaflet or label to the physician. 
V primeru nenamernega zaužitju zdravila ali če vzdraženje kože ali oči vztraja, se takoj posvetujte z zdravnikom in mu pokažite navodilo za uporabo ali ovojnino.
Moxidectin is absorbed through the skin, reaching maximum plasma concentrations approximately 1 to 2 days after treatment in cats. 
Pri mačkah doseže najvišjo plazemsko koncentracijo v 1 do 2 dneh po nanosu.
Benzyl alcohol Butylhydroxytoluene 1 mg/ml (E 321; as antioxidant). 
benzilalkohol 1 mg/ml butilhidroksitoluena (E321; kot antioksidant).
Heartworm prevention (Dirofilaria immitis) 
Zaščita pred okužbo z Dirofilaria immitis
Use of the product may result in transient pruritus in dogs. 
Pri psih se lahko pojavi prehodna srbečica.
Eucoleus (syn. 
Eucoleus (sinonim Capillaria)
• the prevention of angiostrongylosis (L4 larvae and immature adults of Angiostrongylus vasorum), 
• preprečevanje angiostrongiloze (oblika L4, nezrele odrasle oblike Angiostrongylus vasorum),
Part the fur on the animal's neck at the base of the skull until the skin is visible. 
Živali razmaknite dlako na zatilju, da bo vidna koža.
Place the tip of the pipette on the skin and gently squeeze the pipette to expel a portion of its contents directly onto the skin. 
Položite konico merilne kapalke na kožo in jo rahlo stisnite, da nanesete ustrezno količino zdravila neposredno na kožo.
For large cats weighing between 4 kg and 8 kg. 
Za velike mačke od 4 - 8 kg telesne mase.
The product was administered to kittens at up to 5 times the recommended dose, every 2 weeks for 6 treatments, and there were no serious safety concerns. 
Mačji mladiči so dobivali do petkratni terapevtski odmerek vsak drugi teden, in po šestkratnem dajanju ni bilo resnih pomislekov glede varnosti.
Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class. 
Pogosta, ponavljajoča uporaba katerega koli antihelmintika, lahko povzroči odpornost zajedavca na antihelmintik.
Advocate should be administered monthly for six consecutive months. 
Zdravilo Advocate dajemo mesečno šest zaporednih mesecev.
Treatment of the eye worm Thelazia callipaeda (adults) A single dose of the product should be administered. 
Zdravljenje infestacije z očesnim črvom Thelazia callipaeda (odrasli) Zadostuje enkratni odmerek zdravila.
The recommended minimum doses are 10 mg/kg bodyweight imidacloprid and 1.0 mg/kg bodyweight moxidectin, equivalent to 0.1 ml/kg bodyweight Advocate for cats. 
Minimalni odmerek je 10 mg imidakloprida na kg telesne mase ter 1,0 mg moksidektina na kg telesne mase, kar ustreza 0,1 ml zdravila Advocate za mačke na kg telesne mase.
Whilst the accuracy of diagnosis of heartworm infection is limited, it is recommended that attempts be made to check the heartworm status of any cat and ferret aged over 6 months, prior to beginning of prophylactic treatment, as use of the product on cats or ferrets which have adult heartworm may cause serious adverse effects, including death. 
Ker dirofilariozo težko diagnosticiramo, priporočamo, da pri vseh mačkah in belih dihurjih, starejših od 6 mesecev, pred dajanjem zdravila preverimo če so invadirani s srčno glisto Dirofilaria immitis, kajti dajanje zdravila mačkam in belim dihurjem, ki so invadirani z odraslo obliko srčne gliste
After application do not stroke or groom animals until the application site is dry. 
Po nanosu ne božajte in negujte živali dokler se mesto nanosa ne posuši.
INDICATION(S) For dogs suffering from, or at risk from, mixed parasitic infections: 
INDIKACIJA(E) Za pse, ki imajo ali so izpostavljeni mešanim parazitarnim infestacijam:
The recommended minimum doses are 10 mg/kg bodyweight imidacloprid and 2.5 mg/kg bodyweight moxidectin, equivalent to 0.1 ml/kg bodyweight Advocate for dogs. 
Minimalni odmerek je 10 mg imidakloprida na kg telesne mase ter 2,5 mg moksidektina na kg telesne mase kar ustreza 0,1 ml zdravila Advocate za pse na kg telesne mase.
0.4 ml and 0.8 ml per pipette. 
merilna kapalka z 0,4 ml in 0,8 ml.
Reverse the cap and use it to twist and remove the seal from the pipette, as shown. 
Vzemite merilno kapalko iz ovojnine, držite jo navpično, zavrtite in snemite pokrov, obrnite ga in prebodite plastično zaporo na merilni kapalki, kot kaže slika.
In case of accidental oral uptake, symptomatic treatment should be administered. 
V primeru nenamernega zaužitja je potrebno uvesti simptomatsko zdravljenje.
For medium dogs weighing between 4 kg and 10 kg. 
Za srednje velike pse od 4 - 10 kg telesne mase.
Advocate for large dogs (> 10-25 kg) 
Advocate za velike pse (> 10-25 kg)
Advocate 250 mg + 62.5 mg spot-on solution for large dogs Imidacloprid, moxidectin 
Advocate 250 mg + 62,5 mg, kožni nanos, raztopina za velike pse imidakloprid, moksidektin
It is therefore recommended that all dogs 6 months of age or more, living in areas endemic for heartworm, should be tested for existing adult heartworm infection before being treated with the product. 
Priporočamo, da pri psih, starih 6 mesecev in več, ki živijo v ogroženem okolju, pred dajanjem zdravila preverimo, če so inficirani z Dirofilaria immitis.
Animal Health Siemensova 2717/4 
Animal Health CZ-Siemensova 2717/4 155 00 Praha 5
For cats, the corresponding “Advocate for cat” product, which contains 100 mg/ml imidacloprid and 10 mg/ml moxidectin, must be used. 
Pri mačkah uporabljamo ustrezno obliko zdravila Advocate za mačke, ki vsebuje 100 mg/ml imidakloprida in 10 mg/ml moksidektina.
The product was administered to ferrets at 5 times the recommended dose, every 2 weeks for 4 treatments, and there was no evidence of adverse effects or undesirable clinical signs. 
Pri belih dihurjih, ki so dobivali petkratni terapevtski odmerek vsak 2. teden, po štirikratnem dajanju ni bilo stranskih učinkov in niso kazali neželenih kliničnih znakov.
Treatment of cutaneous dirofilariosis (skin worm) (adult stages of Dirofilaria repens) 
Zdravljenje kožne oblike dirofilarioze (kožna glista) (odrasle oblike Dirofilaria repens)
MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS Advocate for large cats 
PODATKI, KI MORAJO BITI NAJMANJ NAVEDENI NA MANJŠIH STIČNIH OVOJNINAH Advocate za velike mačke
Treatment of Aelurostrongylus abstrusus 
Zdravljenje infestacije s pljučnim črvom Aelurostrongylus abstrusus
Each 0.8 ml pipette contains: Active substances: 80 mg imidacloprid, 8 mg moxidectin 
Zdravilni učinkovini: 80 mg imidakloprida, 8 mg moksidektina
Advocate for medium dogs (> 4-10 kg) 
Advocate za srednje velike pse (> 4 - 10 kg)
Flea treatment and prevention (Ctenocephalides felis) One treatment prevents further flea infestation for 4 weeks. 
Zdravljenje in preprečevaje bolhavosti (Ctenocephalides felis) Enkratni nanos ščiti gostitelja pred infestacijo z bolhami štiri tedne.
For dogs, the corresponding “Advocate for dog” product, which contains 100 mg/ml imidacloprid and 25 mg/ml moxidectin, must be used. 
Pri psih uporabljamo ustrezno obliko zdravila Advocate za pse, ki vsebuje 100 mg/ml imidakloprida in 25 mg/ml moksidektina.
Treatment of notoedric mange (Notoedres cati) 
Notoedres (pršice vrste Notoedres cati)
Blister pack containing 1, 2, 3, 4, 6, 9, 12, 21 or 42 unit dose pipettes. 
pretisni omot z 1, 2, 3, 4, 6, 9, 12, 21 ali 42 merilnimi kapalkami za enkratno dajanje.
Existing pupae in the environment may emerge for 6 weeks or longer after treatment is initiated, depending upon climatic conditions. 
Ponovna infestacija z novimi bolhami iz okolice lahko, glede na klimatske razmere, traja šest tednov ali dlje po začetnem nanosu.
For small cats weighing 4 kg or less and ferrets 
Za male mačke do 4 kg telesne mase in bele dihurje
> 4-10 kg Advocate for medium dogs > 10-25 kg Advocate for large dogs > 25-40 kg Advocate for extra-large dogs > 40 kg the appropriate combination of pipettes 
0,4 najmanj 10 najmanj 2,5 > 4-10 kg Advocate za srednje velike pse 1,0 > 10-25 kg Advocate za velike pse > 25-40 kg Advocate za zelo velike pse > 40 kg ustrezna velikost merilne kapalke
Each 2.5 ml pipette contains: Active substances: 250 mg imidacloprid, 62.5 mg moxidectin. 
Zdravilni učinkovini: 250 mg imidakloprida, 62,5 mg moksidektina
Advocate for cats contains 100 mg/ml imidacloprid and 10 mg/ml moxidectin. 
mg/ml imidakloprida in 10 mg/ml moksidektina.
• the treatment of notoedric mange (Notoedres cati), 
• zdravljenje garjavosti, ki jo povzročajo pršice vrste Notoedres (Notoedres cati),
Pre-existing pupae in the environment may continue to emerge for 6 weeks or longer after treatment is initiated depending upon climatic conditions. 
Ponovna infestacija z novimi bolhami iz okolice lahko traja, glede na klimatske razmere, šest tednov ali dlje po začetnem nanosu.
• the treatment of biting lice (Trichodectes canis), 
• uši (Trichodectes canis),
Flea treatment and prevention (Ctenocephalides felis) One treatment prevents future flea infestation for 4 weeks. 
Zdravljenje in preprečevaje bolhavosti (Ctenocephalides felis) Enkratni nanos ščiti gostitelja pred infestacijo z bolhami 3 tedne.
Angiostrongylus 
Angiostrongylus vasorum.
Advocate 80 mg + 8 mg spot-on solution for large cats Imidacloprid, moxidectin 
Advocate 80 mg + 8 mg, kožni nanos, raztopina za velike mačke imidakloprid, moksidektin
The product should be administered monthly for four consecutive months. 
Zdravilo dajemo mesečno štiri zaporedne mesece.
Advocate for extra-large dogs (> 25-40 kg) 
Advocate za zelo velike pse (> 25- 40 kg)
Cats, ferrets 
Kožni nanos, raztopina
For dogs up to 25 kg: 
Pri psih do 25 kg telesne mase
for cats 
Teža mačke
Interaction with other medicinal products and other forms of interaction: During treatment with Advocate no other antiparasitic macrocyclic lactone should be administered. 
Med zdravljenjem živali z zdravilom Advocate, ne nanašajte drugih antiparazitikov iz skupine makrocikličnih laktonov.
Skin worm 
Kožni nanos
For cats suffering from, or at risk from, mixed parasitic infections: 
Za mačke, ki imajo ali so izpostavljene mešanim parazitarnim infestacijam:
4.9 Amounts to be administered and administration route Dosage schedule: 
4.9 Odmerjanje in pot uporabe Odmerjanje:
Advocate for large cats (> 4-8 kg) 
Advocate za velike mačke ≥ 4-8 kg
• the treatment and prevention of flea infestation (Ctenocephalides felis), 
• uničevanje in zatiranje bolh (Ctenocephalides felis),
Correct application will minimise licking of the application sites. 
S pravilnim nanosom zdravila zmanjšamo možnost, da bi psi mesto aplikacije lizali.
In endemic areas regular monthly applications will prevent angiostrongylosis and patent infection with Angiostrongylus vasorum. 
V endemičnih področjih bomo z rednim mesečnim nanosom zdravila preprečevali okužbe z
For extra-large dogs weighing between 25 kg and 40 kg. 
Za zelo velike pse od 25 - 40 kg telesne mase.
MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS Advocate for medium dogs 
PODATKI, KI MORAJO BITI MAJMANJ NAVEDENI NA MANJŠIH STIČNIH OVOJNINAH Advocate za srednje velike pse
For large dogs weighing between 10 kg and 25 kg. 
Za velike pse od 10 - 25 kg telesne mase.
Capillaria) boehmi (adults), 
Zdravljenje Eucoleus (sinonim Capillaria) boehmi (odrasli).
Clear yellow to brownish solution. 
Bistra, rumena do rjavkasta raztopina.
Only “Advocate for small cats and ferrets” (0.4 ml) must be used. 
Dajemo ustrezno obliko zdravila Advocate za male mačke in bele dihurje (0,4 ml).
For small dogs weighing 4 kg or less. 
Za male pse do 4 kg telesne mase.
PARTICULARS TO APPEAR ON THE OUTER PACKAGE Carton, pack size of 1, 2, 3, 4, 6, 9, 12, 21 and 42 pipettes 
PODATKI NA ZUNANJI OVOJNINI Škatla, velikost pakiranja - 1, 2, 3, 4, 6, 9, 12, 21, 42 merilnih kapalk
Application at the base of the skull will minimise the opportunity for the animal to lick the product. 
S pravilnim nanosom zdravila zmanjšamo možnost, da bi žival mesto aplikacije lizala.
Each 1 ml pipette contains: Active substances: 100 mg imidacloprid, 25 mg moxidectin. 
Zdravilni učinkovini: 100 mg imidakloprida, 25 mg moksidektina
Pack sizes: 0.4 ml and 0.8 ml per pipette; blister packs containing 1, 2, 3, 4, 6, 9, 12, 21 or 42 unit dose pipettes. 
merilna kapalka s po 0,4 ml in 0,8 ml pretisni omoti z 1, 2, 3, 4, 6, 9, 12, 21 in 42 merilnimi kapalkami (enotami odmerka)
At each spot part the coat until the skin is visible. 
Razmaknite dlako, da bo vidna koža.
Up to 10 times the recommended dose was tolerated in cats with no evidence of adverse effects or undesirable clinical signs. 
Pri dajanju desetkratnega terapevtskega odmerka pri mačkah ni bilo neželenih kliničnih znakov.
Bayer Animal Health GmbH, 51368 Leverkusen, GERMANY 
Bayer Animal Health GmbH, 51368 Leverkusen, Nemčija
Treatment of Crenosoma vulpis 
Angiostrongylus vasorum Zdravljenje okužb s Crenosoma vulpis
The treatment of animals weighing less than 1 kg should be based on a benefit-risk assessment. 
Pri živalih, lažjih od 1 kg, je potrebno pred dajanjem oceniti razmerje korist/tveganje.
Roundworm, hookworm and whipworm treatment (Toxocara canis, Ancylostoma caninum, Uncinaria stenocephala, Toxascaris leonina and Trichuris vulpis). 
Preprečevanje infestacij z različnimi vrstami glist (Toxocara canis, Ancylostoma caninum, Uncinaria stenocephala, Toxascaris leonina in Trichuris vulpis).
• the treatment of ear mite infestation (Otodectes cynotis), sarcoptic mange (caused by Sarcoptes scabiei var. canis), demodicosis (caused by Demodex canis), 
• uši (Trichodectes canis), • zdravljenje ušesnih garij (Otodectes cynotis), garij vrste Sarcoptes (Sarcoptes scabiei var.
The mean T ½ in cats ranges between 18.7 and 25.7 days. 
Počasi se izloča iz plazme, kar lahko preverimo z merjenjem koncentracije moksidektina v plazmi v času od nanosa do naslednje aplikacije po mesecu dni.Povprečni T1/2 se pri mačkah giblje med 18,7 in 25,7 dnevi.
For prevention of heartworm disease and cutaneous dirofilariosis, the product must be applied at regular monthly intervals during the time of the year when mosquitoes (the intermediate hosts which carry and transmit D. immitis and D. repens larvae) are present. 
Enkratni mesečni odmerek zadostuje za preprečevanje infestacij z Dirofilaria immitis in preprečevanje kožne oblike dirofilarioze v obdobju, ko se v okolici nahajajo komarji (vmesni gostitelji in prenašalci ličinke Dirofilaria immitisin D.repens).
Advocate 40 mg + 10 mg spot-on solution for small dogs Imidacloprid, moxidectin 
Advocate 40 mg + 10 mg, kožni nanos, raztopina za male pse imidakloprid, moksidektin
• the treatment of infections with gastrointestinal nematodes (L4 larvae, immature adults and adults of Toxocara canis, Ancylostoma caninum and Uncinaria stenocephala, adults of Toxascaris leonina and Trichuris vulpis). 
• zdravljenje okužb z želodčno-črevesnimi nematodi (oblika L4, nezrele odrasle in odrasle oblike Toxocara canis, Ancylostma caninum in Uncinaria stenocephala, odrasle oblike Toxascaris leonina in Trichuris vulpis).
Oral uptake by Collie or Old English Sheep dogs and related breeds or crossbreeds should be prevented. 
Pazite, da škotski mejni ovčarji ali staroangleški ovčarji, njim sorodne pasme in njihovi mešanci, zdravila ne zaužijejo.
• the treatment of infections with gastrointestinal nematodes (L4 larvae, immature adults and adults of Toxocara cati and Ancylostoma tubaeforme). 
• zdravljenje okužb z želodčno-črevesnimi nematodi (oblika L4, nezrele odrasle in odrasle oblike Toxocara cati in Ancylostma tubaeforme).
It is recommended that cats and ferrets living in, or travelling to areas endemic for heartworm are treated monthly with the product to protect them from heartworm disease. 
Mačke in bele dihurje, ki živijo ali potujejo na področja, kjer je dirofilarioza endemična, zdravimo enkrat mesečno.
Each unit dose pipette contains: 
1 ml merilna kapalka vsebuje:
Advocate 40 mg + 10 mg spot-on solution for small dogs Advocate 100 mg + 25 mg spot-on solution for medium dogs Advocate 250 mg + 62.5 mg spot-on solution for large dogs Advocate 400 mg + 100 mg spot-on solution for extra-large dogs Imidacloprid, moxidectin 
Advocate 40 mg + 10 mg, kožni nanos, raztopina za male pse Advocate 100 mg + 25 mg, kožni nanos, raztopina za srednje velike pse Advocate 250 mg + 62,5 mg, kožni nanos, raztopina za velike pse Advocate 400 mg + 100 mg, kožni nanos, raztopina za zelo velike pse imidakloprid, moksidektin
Advocate 100 mg + 25 mg spot-on solution for medium dogs Imidacloprid, moxidectin 
Advocate 100 mg + 25 mg, kožni nanos, raztopina za srednje velike pse imidakloprid, moksidektin
> 4-8 kg Advocate for large cats > 8 kg appropriate combination of pipettes 
Advocate za velike mačke ≥ 4-8 kg 0,8 ml
• the prevention of lungworm disease (L3/L4 larvae of Aelurostrongylus abstrusus), 
• zaščita pred angiostrongilozo (pred ličinkami oblik L3 in L4 pljučnega črva Aelurostrongylus abstrusus)
Each 4 ml pipette contains: Active substances: 400 mg imidacloprid, 100 mg moxidectin. 
Zdravilni učinkovini: 400 mg imidakloprida, 100 mg moksidektina
• the prevention of cutaneous dirofilariosis (skinworm) (L3 larvae of Dirofilaria repens), 
• preprečevanje pred kožno obliko dirofilarioze (kožna glista) (oblika L3 Dirofilaria repens),
Advocate should not enter water courses as this may be dangerous for fish and other aquatic organism: moxidectin is highly toxic to aquatic organisms. 
Zdravilo Advocate ne sme priti v vodne ekosisteme, ker je nevaren za ribe in druge vodne organizme.
Advocate for small cats (≤ 4 kg) and ferrets 
Advocate za male mačke ≤ 4 kg in bele dihurje
Advocate 40 mg + 4 mg spot-on solution for small cats and ferrets Advocate 80 mg + 8 mg spot-on solution for large cats 
Advocate 40 mg + 4 mg, kožni nanos, raztopina za male mačke in bele dihurje Advocate 80 mg + 8 mg, kožni nanos, raztopina za velike mačke
For ferrets suffering from, or at risk from, mixed parasitic infections: 
Za bele dihurje, ki imajo ali so izpostavljeni mešanim parazitarnim infestacijam:
Due to the weak nature of the interaction with mammalian nicotinergic receptors and the postulated poor penetration through the blood-brain barrier in mammals, it has virtually no effect on the mammalian CNS. 
Selektivna toksičnost temelji na zelo slabi interakciji s strukturno različnimi nikotinergičnimi receptorji pri sesalcih, kakor tudi na omejenem prehajanju skozi njihovo krvnomožgansko pregrado.
Advocate 40 mg + 10 mg spot-on solution for small dogs Advocate 100 mg + 25 mg spot-on solution for medium dogs Advocate 250 mg + 62.5 mg spot-on solution for large dogs Advocate 400 mg + 100 mg spot-on solution for extra-large dogs 
Advocate 40 mg + 10 mg, kožni nanos, raztopina za male pse Advocate 100 mg + 25 mg, kožni nanos, raztopina za srednje velike pse Advocate 250 mg + 62,5 mg, kožni nanos, raztopina za velike pse Advocate 400 mg + 100 mg, kožni nanos, raztopina za zelo velike pse
Up to 10 times the recommended dose was tolerated in adult dogs with no evidence of adverse effects or undesirable clinical signs. 
Pri aplikaciji desetkratnega terapevtskega odmerka pri odraslih psih ni bilo neželenih kliničnih znakov.
Treatment of the lungworm Eucoleus aerophilus (syn. 
Zdravljenje infestacije pljuč z glisto Eucoleus aerophilus (sinonim Capillaria aerophila) (odrasli).
• the prevention of cutaneous dirofilariosis (L3 larvae of Dirofilaria repens), 
• preprečevanje pred kožno obliko dirofilarioze (oblika L3 Dirofilaria repens),
For dogs suffering from, or at risk from, mixed parasitic infections: 
Za pse, ki imajo ali so izpostavljeni mešanim parazitarnim infestacijam:
Pipette size to be used Volume [ml] 
Velikost merilne kapalke Količina [ml]