natgillin/translations-raw huggingface dataset:
Evotaz contains two active substances: atazanavir and cobicistat. 
Zdravilo Evotaz vsebuje dve zdravilni učinkovini: atazanavir in kobicistat.
How does Evotaz work? 
Kako zdravilo Evotaz deluje?
Evotaz contains the active substances atazanavir and cobicistat. 
Zdravilo Evotaz vsebuje zdravilni učinkovini atazanavir in kobicistat.
Subcutaneous use vial (glass) 
150 mg prašek za raztopino za injiciranje subkutana uporaba viala (steklena)
1 ml (150 mg/ml) 6 (3 x 2) pre-filled syringes (multipack) 
1 ml (150 mg/ml) 6 (3 x 2) napolnjenih injekcijskih peresnikov (skupno pakiranje)
1 ml (150 mg/ml) 6 (3 x 2) pre-filled pens (multipack) 
1 ml (150 mg/ml) 6 (3 x 2) napolnjenih injekcijskih brizg (skupno pakiranje)
1 ml (150 mg/ml) 2 pre-filled syringes 
1 ml (150 mg/ml) 2 napolnjena injekcijska peresnika
1 ml (150 mg/ml) 1 pre-filled syringe 
1 ml (150 mg/ml) 1 napolnjena injekcijska brizga
1 ml (150 mg/ml) 2 pre-filled pens 
1 ml (150 mg/ml) 2 napolnjeni injekcijski brizgi
This is a summary of the European public assessment report (EPAR) for Kovaltry. 
To je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Kovaltry.
What measures are being taken to ensure the safe and effective use of Kovaltry? 
Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Kovaltry?
Other information about Kovaltry 
Druge informacije o zdravilu Kovaltry
The full EPAR and risk management plan summary for Kovaltry can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports. 
Celotno evropsko javno poročilo o oceni zdravila (EPAR) in povzetek načrta obvladovanja tveganj za zdravilo Kovaltry sta na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
The Agency's Committee for Medicinal Products for Human Use (CHMP) decided that Kovaltry's benefits are greater than its risks and recommended that it be approved for use in the EU. 
Odbor za zdravila za uporabo v humani medicini (CHMP) pri agenciji je zaključil, da so koristi zdravila Kovaltry večje od z njim povezanih tveganj, in priporočil, da se odobri za uporabo v EU.
If they occur they may include: angioedema (swelling of tissues under the skin), burning and stinging at the injection site, chills, flushing, itchy rash over the whole body, headache, hives, hypotension (low blood pressure), lethargy, nausea (feeling sick), restlessness, tachycardia (rapid heartbeat), tightness of the chest, tingling, vomiting and wheezing. 
Če se pojavijo, lahko vključujejo angioedem (otekanje podkožnega tkiva), pekoč občutek in zbadanje na mestu injiciranja, mrzlico, rdečico, srbeč izpuščaj po vsem telesu, glavobol, koprivnico, hipotenzijo (nizek krvni tlak), letargijo, navzejo (slabost), nemir, tahikardijo (pospešen srčni utrip), tiščanje v prsnem košu, mravljinčenje, bruhanje in sopenje.
Data from a supportive study also confirmed the benefits of preventative treatment with Kovaltry in reducing the number of bleeds. 
Tudi podatki podporne študije so potrdili koristi preventivnega zdravljenja z zdravilom Kovaltry pri zmanjševanju števila krvavitev.
A risk management plan has been developed to ensure that Kovaltry is used as safely as possible. 
Za zagotovitev čim varnejše uporabe zdravila Kovaltry je bil pripravljen načrt obvladovanja tveganj.
It is not intended to provide practical advice on how to use Kovaltry. 
Povzetek ni namenjen zagotavljanju praktičnih nasvetov o njegovi uporabi.
Why is Kovaltry approved? 
Zakaj je bilo zdravilo Kovaltry odobreno?
What are the risks associated with Kovaltry? 
Kakšna tveganja so povezana z zdravilom Kovaltry?
The dose and frequency of the injections depend on whether Kovaltry is used to treat or prevent bleeding, the severity of the patient's factor VIII deficiency, the extent and location of the bleeding and the patient's condition and bodyweight. 
Odmerek in pogostnost injiciranja sta odvisna od tega, ali se zdravilo Kovaltry uporablja za zdravljenje ali preprečevanje krvavitve, od resnosti bolnikovega pomanjkanja faktorja VIII, obsega in mesta krvavitve ter bolnikovega stanja in telesne mase.
Kovaltry has been shown to be effective in both preventing and treating bleeds, including managing blood loss during surgery, and can be used in all age groups. 
Dokazali so, da je zdravilo Kovaltry učinkovito pri preprečevanju in zdravljenju krvavite, vključno z obvladovanjem izgube krvi med kirurškimi posegi, in se lahko uporablja pri vseh starostnih skupinah.
What is Kovaltry and what is it used for? 
Kaj je zdravilo Kovaltry in za kaj se uporablja?
What benefits of Kovaltry have been shown in studies? 
Kakšne koristi je zdravilo Kovaltry izkazalo v študijah?
A second study involved 51 children under 12 years of age previously treated with other factor VIII products, who also had 3.8 bleeds per year on average during treatment with Kovaltry (mostly related to injuries). 
Druga študija je vključevala 51 otrok, mlajših od 12 let, ki so se predhodno zdravili z drugimi zdravili s faktorjem VIII in so med zdravljenjem z zdravilom Kovaltry prav tako doživeli 3,8 krvavitve na leto (večinoma v povezavi s poškodbami).
The active substance in Kovaltry, octocog alfa, works in the body in the same way as human factor VIII. 
Zdravilna učinkovina zdravila Kovaltry, oktokog alfa, deluje v telesu enako kot humani faktor VIII.
Based on this plan, safety information has been included in the summary of product characteristics and the package leaflet for Kovaltry, including the appropriate precautions to be followed by healthcare professionals and patients. 
V skladu s tem načrtom so bile v povzetek glavnih značilnosti zdravila in navodilo za njegovo uporabo vključene informacije o varnosti, vključno s previdnostnimi ukrepi, ki jih morajo upoštevati zdravstveni delavci in bolniki.
For the full list of all side effects and restrictions with Kovaltry, see the package leaflet. 
Za celoten seznam neželenih učinkov in omejitev pri uporabi zdravila Kovaltry glejte navodilo za uporabo.
Kovaltry can only be obtained with a prescription and treatment should be under the supervision of a doctor who has experience in the treatment of haemophilia. 
Izdaja zdravila Kovaltry je le na recept, zdravljenje z njim pa mora biti pod nadzorom zdravnika z izkušnjami z zdravljenjem hemofilije.
Kovaltry is a medicine used for the treatment and prevention of bleeding in patients with haemophilia A (an inherited bleeding disorder caused by lack of a clotting protein called factor VIII). 
Kovaltry je zdravilo, ki se uporablja za zdravljenje in preprečevanje krvavitev pri bolnikih s hemofilijo A (prirojeno motnjo strjevanja krvi zaradi pomanjkanja koagulacijske beljakovine, imenovane faktor VIII).
The effectiveness of Kovaltry in preventing and treating bleeding has been shown in a main study involving 62 patients aged 12 years or older with severe haemophilia A who were previously treated with other factor VIII products. 
Učinkovitost zdravila Kovaltry pri preprečevanju in zdravljenju krvavitev so dokazali v glavni študiji, ki je vključevala 62 bolnikov, starejših od 12 let, s hudo obliko hemofilije A, ki so se predhodno zdravili z drugimi zdravili s faktorjem VIII.
Kovaltry is available as a powder and solvent used to make a solution for injection. 
Zdravilo Kovaltry je na voljo kot prašek in vehikel za pripravo raztopine za injiciranje.
In addition, the company that markets Kovaltry will complete studies to investigate the safety and efficacy of the medicine in patients who have not previously been treated with other factor VIII products, and to provide further evidence of the safety and efficacy of long-term treatment with Kovaltry in children. 
Poleg tega bo podjetje, ki trži zdravilo Kovaltry, izvedlo študije, s katerimi bodo proučili varnost in učinkovitost zdravila pri bolnikih, ki se predhodno niso zdravili z drugimi zdravili s faktorjem VIII, in zagotovili dodatne dokaze o varnosti in učinkovitosti dolgotrajnega zdravljenja z zdravilom Kovaltry pri otrocih.
For more information about treatment with Kovaltry, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist. 
Za več informacij o zdravljenju z zdravilom Kovaltry preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte z zdravnikom ali farmacevtom.
This compared with an average of 6.9 bleeds per year before Kovaltry treatment. 
To povprečje je pred zdravljenjem z zdravilom Kovaltry znašalo 6,9 krvavitve na leto.
Hypersensitivity (allergic) reactions are uncommon with Kovaltry, affecting from 1 patient in 1,000 to less than 1 patient in 100. 
Občasno so pri zdravilu Kovaltry opazili preobčutljivostne (alergijske) reakcije, ki prizadenejo med 1 osebo od 1 000 in manj kot 1 osebo od 100.
The number of bleeds that occurred during Kovaltry treatment was calculated as 3.8 bleeds per year on average (mostly into joints). 
Število krvavitev med zdravljenjem z zdravilom Kovaltry so z izračunom pretvorili v povprečno 3,8 krvavitve na leto (večinoma v sklepe).
For practical information about using Kovaltry, patients should read the package leaflet or contact their doctor or pharmacist. 
Za praktične informacije o uporabi zdravila Kovaltry naj bolniki preberejo navodilo za uporabo ali se posvetujejo z zdravnikom ali farmacevtom.
About 70% of the bleeding events that occurred were managed with a single injection of Kovaltry, and about another 15% responded to a second injection; the response was considered good or excellent in around 80% of cases. 
Približno 70 % krvavitev, ki so se pojavile, so obvladali z enkratno injekcijo zdravila Kovaltry, naslednjih 15 % pa se je odzvalo na drugo injekcijo.
How does Kovaltry work? 
Kako zdravilo Kovaltry deluje?
How is Kovaltry used? 
Kako se zdravilo Kovaltry uporablja?
Further information on Tyverb can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports. 
Nadaljnje informacije o zdravilu Tyverb so na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
All of the tablets must be taken together at the same time every day, at least 1 hour before or 1 hour after food. 
Vse tablete je treba vzeti sočasno vsak dan ob istem času, najmanj eno uro pred obrokom ali eno uro po njem.
This means that there was more evidence to come about the effectiveness of the medicine. 
To pomeni, da se je pričakovalo še več dokazov o učinkovitosti zdravila.
This was switched to a full marketing authorisation on 17 February 2015. 
To je bilo 17. februarja 2015 spremenjeno v običajno dovoljenje za promet.
Tyverb is used in the following ways: 
Zdravilo Tyverb se uporablja na naslednje načine:
What measures are being taken to ensure the safe and effective use of Tyverb? 
Kateri ukrepi se izvajajo za zagotovitev varne in učinkovite uporabe zdravila Tyverb?
The European Medicines Agency decided that Tyverb's benefits are greater than its risks and it can be authorised for use in the EU. 
Evropska agencija za zdravila je zaključila, da so koristi zdravila Tyverb večje od z njim povezanih tveganj in da se lahko odobri za uporabo v EU.
In all the studies, the main measure of effectiveness was how long the patients lived without their disease getting worse, which was assessed in scans. 
V vseh študijah je bilo glavno merilo učinkovitosti čas, kako dolgo so bolnice živele, ne da bi se bolezen poslabšala, kar se je ocenjevalo s slikanjem.
Tyverb received a conditional marketing authorisation valid throughout the EU on 10 June 2008. 
Za zdravilo Tyverb je bilo 10. junija 2008 izdano pogojno dovoljenje za promet, veljavno po vsej EU.
This combination is used in women who do not currently need to receive standard chemotherapy to treat their cancer. 
Ta kombinacija se uporablja pri ženskah, ki za zdravljenje raka trenutno ne potrebujejo standardne kemoterapije.
The studies also looked at how long the patients survived. 
V študijah so prav tako proučevali čas preživetja bolnic.
The doctor may decide to interrupt or stop treatment in patients experiencing certain side effects, especially those affecting the heart, lungs or liver. 
Zdravnik se lahko odloči za začasno prekinitev ali prenehanje zdravljenja pri bolnicah, ki imajo določene neželene učinke, zlasti tiste, ki prizadenejo srce, pljuča ali jetra.
As for all medicines, data on the use of Tyverb are continuously monitored. 
Tako kot za vsako zdravilo se tudi podatki o uporabi zdravila Tyverb stalno spremljajo.
Other information about Tyverb 
Druge informacije o zdravilu Tyverb
What benefits of Tyverb have been shown in studies? 
Kakšne koristi je zdravilo Tyverb izkazalo v študijah?
Why is Tyverb authorised in the EU? 
Zakaj je bilo zdravilo Tyverb odobreno v EU?
What is Tyverb and what is it used for? 
Kaj je zdravilo Tyverb in za kaj se uporablja?
Tyverb was originally given ‘conditional approval'. 
Zdravilo Tyverb je prvotno pridobilo „pogojno dovoljenje za promet“.
What are the risks associated with Tyverb? 
Kakšna tveganja so povezana z zdravilom Tyverb?
Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Tyverb have also been included in the summary of product characteristics and the package leaflet. 
Priporočila in varnostni ukrepi, ki jih morajo za varno in učinkovito uporabo zdravila Tyverb upoštevati zdravstveni delavci in bolniki, so vključeni tudi v povzetek glavnih značilnosti zdravila in navodilo za njegovo uporabo.
‘Advanced' means that the cancer has started to spread and ‘metastatic' means that the cancer has already spread to other parts of the body; 
„Napredovali“ pomeni, da se je rak začel širiti, „metastatski“ pa, da se je že razširil na druge dele telesa;
Tyverb is available as tablets (250 mg) and the recommended dose is 4 tablets a day when used with trastuzumab, 5 tablets a day when it is used with capecitabine, and 6 tablets a day when taken with an aromatase inhibitor. 
Zdravilo Tyverb je na voljo v obliki tablet (250 mg), pri čemer je priporočeni odmerek štiri tablete na dan, če se uporablja v kombinaciji s trastuzumabom, pet tablet na dan, če se uporablja v kombinaciji s kapecitabinom, in šest tablet na dan, če se uporablja v kombinaciji z zaviralci aromataze.
Patients who stop taking Tyverb after developing severe liver problems should not start to take the medicine again. 
Bolnice, ki prenehajo jemati zdravilo Tyverb po tem, ko so se pri njih pojavile hude težave z jetri, zdravila ne smejo začeti ponovno jemati.
If patients start to take Tyverb again, they may need to use a lower dose. 
Če se zdravljenje z zdravilom Tyverb uvaja ponovno, bo morda potreben manjši odmerek.
An overview of Tyverb and why it is authorised in the EU 
Pregled zdravila Tyverb in zakaj je odobreno v EU
For more information about using Tyverb, see the package leaflet or contact your doctor or pharmacist. 
Za več informacij glede uporabe zdravila Tyverb glejte navodilo za uporabo ali se posvetujte z zdravnikom ali farmacevtom.
Tyverb in combination with another cancer medicine was shown to be more effective than the comparator treatment in three main studies involving women with breast cancer. 
Zdravilo Tyverb se je v kombinaciji z drugimi zdravili za zdravljenje raka izkazalo za učinkovitejše od primerjalnega zdravljenja v treh glavnih študijah, v katere so bile vključene ženske z rakom dojke.
Side effects reported with Tyverb are carefully evaluated and any necessary action taken to protect patients. 
Neželeni učinki, o katerih so poročali pri zdravilu Tyverb, se skrbno ovrednotijo in po potrebi se sprejmejo ukrepi za zaščito bolnic.
219 of the women had cancer that was producing large quantities of HER2. 
219 žensk je imelo raka, ki je izražal velike količine HER-2.
The active substance in Tyverb, lapatinib, belongs to a group of medicines called protein kinase inhibitors. 
Učinkovina v zdravilu Tyverb, lapatinib, spada v skupino zdravil, imenovanih zaviralci proteinske kinaze.
The women had not received trastuzumab or an aromatase inhibitor before entering this study. 
Bolnice pred začetkom študije še niso prejemale trastuzumaba ali zaviralcev aromataze.
These medicines work by blocking enzymes known as protein kinases, which can be found in some receptors (targets) on the surface of cancer cells including HER2. 
Ta zdravila delujejo tako, da zavirajo vrste encimov, znane kot proteinske kinaze, ki jih najdemo v nekaterih receptorjih (prijemališčih) na površini rakavih celic, med drugim tudi pri beljakovini HER-2.
It involved 1,286 women who had been through the menopause with metastatic breast cancer that was sensitive to hormones. 
Vanjo je bilo vključenih 1 286 žensk po menopavzi, ki so imele metastatski rak dojke, občutljiv za hormone.
Tyverb can only be obtained with a prescription and should only be started by a doctor who has experience in giving cancer medicines. 
Predpisovanje in izdaja zdravila Tyverb je le na recept, zdravljenje z njim pa sme uvesti samo zdravnik, ki ima izkušnje z uporabo zdravil za zdravljenje raka.
It involved 296 women with metastatic disease that was producing large quantities of HER2 and got worse despite treatment with trastuzumab and other cancer medicines (including anthracyclines and taxanes). 
Vanjo je bilo vključenih 296 žensk z metastatskim rakom, ki je izražal velike količine HER-2, njihovo stanje pa se je poslabšalo kljub zdravljenju s trastuzumabom in drugimi zdravili za zdravljenje raka (vključno z antraciklini in taksani).
The company that markets Tyverb will evaluate ways to predict resistance (the medicine becoming less effective) in breast cancer patients taking Tyverb with other cancer medicines. 
Podjetje, ki trži zdravilo Tyverb, bo ocenilo načine napovedovanja odpornosti (ko zdravilo postane manj učinkovito) pri bolnicah z rakom dojke, ki zdravilo Tyverb jemljejo v kombinaciji z drugimi zdravili za zdravljenje raka.
The most common side effects with Tyverb (which may affect more than 1 in 4 patients) are rash and side effects affecting the stomach and gut (such as diarrhoea, nausea (feeling sick) and vomiting). 
Najpogostejši neželeni učinki zdravila Tyverb (opaženi pri več kot četrtini bolnic) so izpuščaji in neželeni učinki, ki prizadenejo želodec in črevesje (kot so driska, slabost in bruhanje).
• in combination with an aromatase inhibitor (another type of cancer medicine) in women who have been through the menopause, when the cancer is metastatic and responds to hormones. 
• v kombinaciji z zaviralcem aromataze (drugo vrsto zdravila za zdravljenje raka) pri ženskah po menopavzi, kadar je rak metastatski in se odziva na hormone.
About a quarter of breast cancers produce HER2. 
Za približno četrtino primerov raka dojke je značilna izražena beljakovina HER-2.
In addition, women taking the combination survived for 14.0 months on average, compared with 9.5 months in those taking Tyverb alone. 
Poleg tega je bil pri ženskah, ki so prejemale kombinacijo zdravil, povprečni čas preživetja 14,0 meseca v primerjavi z 9,5 meseca pri ženskah, ki so prejemale le zdravilo Tyverb.
Tyverb contains the active substance lapatinib. 
Zdravilo Tyverb vsebuje učinkovino lapatinib.
• in combination with trastuzumab for metastatic cancer that does not respond to hormones (hormone receptor-negative disease), and which got worse when previously treated with a combination of trastuzumab and other cancer medicines (chemotherapy); 
• v kombinaciji s trastuzumabom za zdravljenje metastatskega raka, ki se ne odziva na hormone (bolezen, ki je negativna na hormonske receptorje) ter se je med predhodnimi zdravljenji s kombinacijo trastuzumaba in drugih zdravil za zdravljenje raka (kemoterapijo) poslabšal;
HER2 is a receptor for a substance called epidermal growth factor which stimulates the cancer cells to grow uncontrollably. 
Beljakovina HER-2 je receptor za snov, imenovano epidermalni rastni faktor, ki spodbuja nenadzorovano širjenje rakavih celic.
How does Tyverb work? 
Kako zdravilo Tyverb deluje?
This means that the cancer produces a specific protein called HER2 (also known as ErbB2) in large quantities on the surface of the cancer cells. 
To pomeni, da na površini rakavih celic v velikih količinah nastaja določena beljakovina, imenovana HER-2 (znana tudi pod imenom ErbB2).
How is Tyverb used? 
Kako se zdravilo Tyverb uporablja?
The third study compared Tyverb with placebo (a dummy treatment), both of which were taken together with letrozole (an aromatase inhibitor). 
V tretji študiji so zdravilo Tyverb primerjali s placebom (zdravilom brez učinkovine), pri čemer so bolnice oboje prejemale v kombinaciji z letrozolom (zaviralcem aromataze).
The women whose cancer was producing large quantities of HER2 taking Tyverb in combination with letrozole survived for an average of 35.4 weeks without their disease getting worse. 
Pri ženskah, katerih rak je izražal velike količine HER-2 in ki so zdravilo Tyverb prejemale v kombinaciji z letrozolom, je bil povprečni čas preživetja brez poslabšanja bolezni 35,4 tedna.
For the full list of side effects and restrictions with Tyverb, see the package leaflet. 
Za celoten seznam vseh neželenih učinkov in omejitev pri uporabi zdravila Tyverb glejte navodilo za uporabo.
The second study compared Tyverb alone with a combination of Tyverb plus trastuzumab. 
V drugi študiji so uporabo zgolj zdravila Tyverb primerjali s kombinacijo zdravila Tyverb in trastuzumaba.
By blocking HER2 receptors, Tyverb helps to control growth of the cancer. 
Zdravilo Tyverb z zaviranjem receptorjev HER-2 prispeva k nadzoru nad širjenjem raka.
Tyverb in combination with other cancer medicines has been shown to improve survival of patients with breast cancer that produces large quantities of HER2, and its side effects are considered acceptable. 
Za zdravilo Tyverb je bilo dokazano, da njegovo prejemanje v kombinaciji s prejemanjem drugih zdravil za zdravljenje raka izboljša preživetje bolnic z rakom dojke, ki izraža velike količine HER-2, njegovi neželeni učinki pa se štejejo za sprejemljive.
Women taking Tyverb with capecitabine survived for an average of 75 weeks, and those taking capecitabine alone survived for an average of 64.7 weeks. 
Pri ženskah, ki so prejemale zdravilo Tyverb v kombinaciji s kapecitabinom, je bil povprečni čas preživetja 75 tednov, pri tistih, ki so prejemale le kapecitabin, pa 64,7 tedna.
• in combination with capecitabine (another cancer medicine) when the cancer is advanced or metastatic and got worse following previous treatment including an anthracycline and a taxane (other types of cancer medicine), and following treatment of the patient's metastatic disease with trastuzumab (another cancer medicine). 
• v kombinaciji s kapecitabinom (drugim zdravilom za zdravljenje raka), če gre za napredovali ali metastatski rak, ki se je po predhodnem zdravljenju z antraciklini in taksani (drugima vrstama zdravil za zdravljenje raka) poslabšal, ter po zdravljenju metastaz s trastuzumabom (drugim zdravilom za zdravljenje raka).
Tyverb is a cancer medicine used to treat patients with breast cancer that has been shown to be ‘expressing' large amounts of HER2. 
Zdravilo Tyverb je zdravilo za zdravljenje raka, ki se uporablja za zdravljenje bolnic z rakom dojke s prekomerno izraženim HER-2.
Women taking Tyverb with trastuzumab lived without their disease getting worse for 12.0 weeks on average, compared with 8.1 weeks in those taking Tyverb alone. 
Bolnice, ki so prejemale zdravilo Tyverb v kombinaciji s trastuzumabom, so v povprečju živele 12,0 tedna brez poslabšanja bolezni, medtem ko je to obdobje pri tistih, ki so prejemale le zdravilo Tyverb, znašalo 8,1 tedna.
The first study compared Tyverb in combination with capecitabine, with capecitabine taken alone. 
V prvi študiji so zdravilo Tyverb v kombinaciji s kapecitabinom primerjali s kapecitabinom kot samostojnim zdravilom.
Palmar-plantar erythrodysaesthesia (rash and numbness on the palms and soles) is also very common when Tyverb is taken with capecitabine. 
Kadar se zdravilo Tyverb jemlje v kombinaciji s kapecitabinom, se zelo pogosto pojavi tudi palmarno-plantarna eritrodisestezija (izpuščaji in otrplost v dlaneh in podplatih).