natgillin/translations-raw huggingface dataset:
Zinc chloride, metacresol, glycerol, hydrochloric acid / sodium hydroxide (for pH adjustment), water for injections. 
Cinkov klorid, metakrezol, glicerol, klorovodikova kislina / natrijev hidroksid (za prilagoditev pH), voda za injekcije.
The strength “300” is highlighted in honey gold on the label of your Toujeo SoloStar pre-filled pen. 
Jakost »300« je poudarjena v medeno zlati barvi na ovojnini vašega Toujeo SoloStar napolnjenega peresnika.
Patients with high insulin doses because of antibodies to human insulin may experience an improved insulin response with Toujeo. 
Bolnikom, ki zaradi protiteles proti humanemu insulinu potrebujejo velike odmerke insulina, se lahko z zdravilom Toujeo izboljša odziv na insulin.
When switching basal insulin to Toujeo, dose reduction of basal and bolus insulin needs to be considered on an individual basis, in order to mimimize the risk of hypoglycaemia (see section 4.4). 
Pri prehodu z bazalnega insulina na zdravilo Toujeo je treba individualno razmisliti o manjši potrebi po bazalnem in bolusnem insulinu, da bi zmanjšali tveganje za hipoglikemijo (glejte poglavje 4.4).
• Take care when handling needles - this is to prevent needle injury and cross-infection. 
• Pri ravnanju z iglami bodite previdni, da boste preprečili poškodbe z iglo in navzkrižno okužbo.
- When switching from Toujeo to insulin glargine 100 units/ml, the dose should be reduced (approximately by 20%) to reduce the risk of hypoglycaemia. 
- Pri prehodu z zdravila Toujeo na insulin glargin 100 enot/ml je treba odmerek zmanjšati (za približno 20%), da bi zmanjšali tveganje za hipoglikemijo.
Results from studies comparing Toujeo and insulin glargine 100 units/ml did not indicate any difference in term of development of anti-insulin antibodies, on efficacy, safety or dose of basal insulin between Toujeo and insulin glargine 100 units/ml. 
Rezultati študij, ki so primerjale zdravilo Toujeo z insulinom glargin 100 enot/ml, niso pokazali razlik, kar zadeva nastanek proti insulinskih protiteles, učinkovitost, varnost ali odmerek bazalnega insulina med zdravilom Toujeo in insulinom glargin 100 enot/ml.
Your blood sugar level may either rise or fall if you take: 
Krvni sladkor se vam lahko zviša ali vam pade, če jemljete:
• Read the Instructions for Use that come with this package leaflet. 
• Preberite navodila, priložena temu navodilu za uporabo.
26 weeks of treatment Patients previously treated with basal insulin 
26 tednov zdravljenja Bolniki, predhodno zdravljeni z bazalnim insulinom
Toujeo can be used in elderly people, renal and hepatic impaired patients, and children and adolescents from the age of 6 years. 
Zdravilo Toujeo se lahko uporablja pri starejših osebah in bolnikih z okvaro ledvic ali jeter, mladostnikih in otrocih od 6. leta starosti naprej.
After subcutaneous injection of Toujeo, the intra-subject variability, defined as the coefficient of variation for the insulin exposure during 24 hours was low at steady state (17.4%). 
Po subkutanem injiciranju zdravila Toujeo je bila intraindividualna variabilnost, izražena s koeficientom variacije izpostavljenosti insulinu v teku 24 ur, v stanju dinamičnega ravnovesja majhna
Packs of 1, 3, 6 (2 packs of 3), 9 (3 packs of 3) and 10 pens are available. 
Na voljo so pakiranja z 1, 3, 6 (2 pakiranja po 3), 9 (3 pakiranja po 3) in 10 peresniki.
This is to avoid dosing errors and potential overdose which may lead to low blood sugar. 
To lahko vodi v napake pri odmerjanju in do previsokega odmerka, kar lahko znatno zniža raven sladkorja v krvi.
No dose re-calculation is required. 
Dodatno preračunavanje odmerka ni potrebno.
• Disopyramide - for some heart problems. 
• Dizopiramid - za zdravljenje določenih težav s srcem.
• Your blood sugar is often too low. 
• Imate pogosto prenizek krvni sladkor.
• Inject it into the front of your thighs, upper arms or the front of your waist (abdomen). 
• Injicirajte ga v sprednji del stegen, nadlakti ali sprednji del trebuha.
The efficacy and safety of Toujeo have been studied in a 1:1 randomized controlled open label clinical trial in children and adolescents with type 1 diabetes mellitus for a period of 26 weeks (n=463). 
Učinkovitost in varnost zdravila Toujeo so v obdobju 26 tednov raziskali v randomiziranem (razmerje 1:1), z zdravilno učinkovino nadzorovanem odprtem kliničnem preskušanju pri otrocih in mladostnikih s sladkorno boleznijo tipa 1 (n = 463).
29 units selected 
izbrani odmerek 29 enot
• If you are blind or have poor eye sight, do not use the pre-filled pen without help. 
• Če ste slepi ali slabo vidite, napolnjenega injekcijskega peresnika ne uporabljajte brez pomoči, ker ne boste mogli prebrati odmernega okenca na peresniku.
Factors increasing the susceptibility to hypoglycaemia require particularly close monitoring and may necessitate dose adjustment. 
Posebej skrbno je treba nadzirati dejavnike, ki povečujejo nagnjenost k hipoglikemiji, in potrebna je lahko prilagoditev odmerka.
A marked change in glycaemic control may cause temporary visual impairment, due to temporary alteration in the turgidity and refractive index of the lens. 
Izrazita sprememba urejenosti glikemije lahko prehodno poslabša vid zaradi prehodno spremenjenega turgorja in lomnega količnika leče.
With Toujeo, it may take longer to recover from low blood sugar because it is long-acting. 
Z zdravilom Toujeo lahko traja dalj časa, da nizek krvni sladkor mine, ker gre za dolgodelujoče zdravilo.
Initiation 
Uvedba
If you don't, your full dose will not be delivered. 
Če tega ne naredite, se lahko zgodi, da ne prejmete celotnega odmerka.
When switching from a treatment regimen with an intermediate or long-acting insulin to a regimen with Toujeo, a change of the dose of the basal insulin may be required and the concomitant anti-hyperglycaemic treatment may need to be adjusted (dose and timing of additional regular insulins or fast-acting insulin analogues or the dose of non-insulin anti-hyperglycaemic medicinal products). 
Pri prehodu s srednjedolgo- ali dolgodelujočega insulina na zdravljenje z zdravilom Toujeo sta lahko potrebni sprememba odmerka bazalnega insulina in prilagoditev sočasnega antihiperglikemičnega zdravljenja (odmerek in časovni razpored dodatnih običajnih insulinov ali hitrodelujočih insulinskih analogov oz. odmerek neinsulinskih antihiperglikemičnih zdravil).
It is used to treat diabetes mellitus in adults, adolescents and children from the age of 6 years. 
To zdravilo se uporablja za zdravljenje sladkorne bolezni pri odraslih, mladostnikih in otrocih od 6. leta starosti naprej.
STEP 5: Inject your dose 
KORAK: Injicirajte odmerek
Beta-blockers 
Zaviralci beta
If you have missed a dose of Toujeo or if you have not injected enough insulin, your blood sugar level may become too high (hyperglycaemia): 
Če ste izpustili odmerek zdravila Toujeo ali niste injicirali dovolj insulina, se vam lahko krvni sladkor preveč zviša (hiperglikemija).
Although Toujeo contains the same active substance as insulin glargine 100 units/ml, these medicines are not interchangeable. 
Zdravilo Toujeo sicer vsebuje isto učinkovino kot insulin glargin 100 enot/ml, vendar ti zdravili nista medsebojno zamenljivi.
The product may be stored for a maximum of 6 weeks below 30°C. 
Zdravilo se shranjuje največ 6 tednov na temperaturi do 30 °C.
If this occurs, patients should increase the frequency of checking their blood glucose levels and might need to administer additional insulin. 
V takšnem primeru si morajo bolniki pogosteje meriti koncentracijo glukoze v krvi in morda potrebujejo dodatni insulin.
- Switching from twice-daily basal insulins to once-daily Toujeo, the recommended initial Toujeo dose is 80% of the total daily dose of basal insulin that is being discontinued. 
- Pri prehodu z bazalnih insulinov dvakrat na dan na zdravilo Toujeo enkrat na dan je priporočeni začetni odmerek zdravila Toujeo 80 % celotnega dnevnega odmerka bazalnega insulina, ki ga je bolnik uporabljal dotlej.
• Other: The Guide for healthcare professionals is also highlighting the distinction between the different Toujeo presentations: That insulin glargine 300 units/ml is available in two different presentations: Toujeo SoloStar (1.5 mL prefilled pen/450 units) and Toujeo DoubleStar (3 mL prefilled pen/900 units). 
• Drugo: Vodnik za zdravstvene delavce izpostavlja tudi razlikovanje med različnimi oblikami zdravila Toujeo: Da je insulin glargin 300 enot/ml na voljo v dveh različnih oblikah: Toujeo SoloStar (1,5-ml napolnjen injekcijski peresnik/450 enot) in Toujeo DoubleStar (3-ml napolnjen injekcijski peresnik/900 enot).
- That dose adjustment is needed when patients are switched from one to the other strength: After titration, on average a 10-18% higher basal insulin dose are needed to achieve target ranges for plasma glucose levels when using the 300 units/ml formulation compared to the 100 units/ml formulation. 
- V primeru prehoda bolnika z ene jakosti na drugo je treba prilagoditi odmerek: Pri uporabi oblike s 300 enot/ml je po titriranju za doseganje ciljnega območja koncentracije glukoze v plazmi potreben povprečno od 10 do 18 % večji odmerek bazalnega insulina kot pri obliki 100 enot/ml.
• For more information, see the box at the end of this leaflet. 
• Za več informacij glejte okvir na koncu tega navodila.
Packs of 1, 3, 5 and 10 pens are available. 
Na voljo so pakiranja z 1, 3, 5 in 10 peresniki.
A Select 4 units by turning the dose selector until the dose pointer is at the 4 mark. 
A Nastavite 4 enote tako, da zavrtite izbirnik odmerka, dokler kazalnik odmerka ne kaže oznake 4.
Physiological concentrations of endogenous IGF-1 may activate the mitogenic-proliferative pathway; however, the therapeutic concentrations found in insulin therapy, 
Fiziološke koncentracije endogenega IGF-1 lahko aktivirajo mitogenoproliferacijsko pot.
Before using Toujeo SoloStar or Toujeo DoubleStar pre-filled pen, the Instructions for Use included in the package leaflet must be read carefully. 
Pred uporabo napolnjenega injekcijskega peresnika Toujeo SoloStar ali Toujeo DoubleStar mora bolnik natančno prebrati navodila z uporabo, navedena na priloženem navodilu za uporabo.
• Serious low blood sugar may cause brain damage and may be life-threatening. 
• Resno znižanje krvnega sladkorja lahko povzroči okvaro možganov in je lahko smrtno nevarno.
In the event of blocked needle, the patients must follow the instructions described in Step 3 of the Instructions for Use accompanying the package leaflet (see section 6.6). 
Če je igla zamašena, mora bolnik upoštevati navodila, opisana v 3. koraku navodil, priloženih navodilu za uporabo zdravila (glejte poglavje 6.6).
When changing from Toujeo SoloStar to Toujeo DoubleStar, if the patient's previous dose was an odd number (e.g. 23 units) then the dose must be increased or decreased by 1 unit (e.g. 24 or 22 units). 
Če je bil bolnikov prejšnji odmerek liho število (npr. 23 enot), je treba odmerek ob prehodu z zdravila Toujeo SoloStar na zdravilo Toujeo DoubleStar povečati ali zmanjšati za 1 enoto (npr. na 24 ali 22 enot).
Examples of signs that your blood sugar level is falling too much or too fast include: sweating, clammy skin, feeling anxious, fast or irregular heart beat, high blood pressure and palpitations. 
Med znaki pretiranega ali prehitrega znižanja krvnega sladkorja so: znojenje, vlažna in lepljiva koža, občutek tesnobe, hitro ali neredno bitje srca, visok krvni tlak in razbijanje srca (palpitacije).
Results from all clinical trials with Toujeo indicated that reductions in HbA1c from baseline to end of trial were non-inferior to insulin glargine 100 units/ml. 
Rezultati vseh kliničnih preskušanj z zdravilom Toujeo so pokazali, da znižanje HbA1c od izhodišča do konca preskušanja ni bilo inferiorno v primerjavi z insulinom glargin 100 enot/ml.
You can select doses from 2 to 160 units in steps of 2 units at a time. 
Izberete lahko odmerke od 2 do 160 enot v korakih po 2 enoti naenkrat.
• Read all of these instructions before using your pen. 
• Pred uporabo peresnika preberite vsa ta navodila.
This is because there is no experience with Toujeo in this age group. 
Z zdravilom Toujeo namreč v tej starostni skupini ni izkušenj.
However, intensification of insulin therapy with abrupt improvement in glycaemic control may be associated with temporary worsening of diabetic retinopathy. 
Vendar se lahko z intenziviranjem insulinskega zdravljenja in nenadnim izboljšanjem urejenosti glikemije diabetična retinopatija prehodno poslabša.
RR: 1.00 [0.95;1.04] 
RT: 1,00 [0,95;1,04]
Table 2: Results from clinical trials in type 2 diabetes mellitus 
Preglednica 2: Rezultati kliničnih preskušanj pri sladkorni bolezni tipa 2
• When insulin comes out of the needle tip, your pen is working correctly. 
• Če iz konice igle pride insulin, peresnik deluje pravilno.
Patients should be informed that the dose counter of Toujeo SoloStar or Toujeo DoubleStar pre-filled pen shows the number of units of Toujeo to be injected. 
Bolnikom je treba povedati, da odmerno okence na napolnjenih injekcijskih peresnikih Toujeo SoloStar in Toujeo DoubleStar kaže število enot zdravila Toujeo, ki bodo injicirane.
Please, see also section 3. 
Prosimo, glejte poglavje 3.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse. 
Če imate dodatna vprašanja o uporabi zdravila, se posvetujte z zdravnikom, farmacevtom ali z medicinsko sestro.
Then eat something (such as bread or pasta) that will raise your blood sugar over a longer time. 
Potem zaužijte nekaj, kar krvni sladkor zviša za dalj časa (na primer kruh ali testenine).
This leaflet was last revised in Other source of information 
Navodilo je bilo nazadnje revidirano dne
Pioglitazone used together with insulin 
Uporaba pioglitazona skupaj z insulinom
• Ensure to use the right insulin. 
• Poskrbite, da boste uporabili pravi insulin.
If you have injected too much of this medicine, your blood sugar level may become too low. 
Če ste uporabili večji odmerek zdravila Toujeo, kot bi smeli Če ste si injicirali preveč tega zdravila, se vam lahko krvni sladkor preveč zniža.
Be familiar with your warning signs. 
Bodite seznanjeni s svojimi opozorilnimi znaki.
• Do not put the pen back in the fridge. 
• Peresnika ne dajte nazaj v hladilnik.
SoloStar pen: 
SoloStar peresnik:
Toujeo is administered subcutaneously by injection in the abdominal wall, the deltoid or the thigh. 
Zdravilo Toujeo je treba injicirati subkutano v trebušno steno, deltoidno mišico ali stegno.
The pen may be stored for a maximum of 6 weeks below 30°C and away from direct heat or direct light. 
Napolnjeni injekcijski peresnik lahko shranjujete največ 6 tednov pri temperaturi do 30 °C in zaščiteno pred neposredno vročino in svetlobo.
If you do not see insulin coming out before taking your dose, you could get an underdose or no insulin at all. 
Če pred uporabo odmerka ne vidite, da bi iz igle prišel insulin, se lahko zgodi, da injicirate premajhen odmerek ali sploh nič insulina.
• check your pen and the needle are working properly. 
• da boste preverili pravilno delovanje peresnika in igle.
- When switching from insulin glargine 100 units/ml to Toujeo, this can be done on a unit-to-unit basis, but a higher Toujeo dose (approximately 10-18%) may be needed to achieve target ranges for plasma glucose levels. 
- Prehod z insulina glargin 100 enot/ml na zdravilo Toujeo je mogoče narediti na podlagi enota-zaenoto, toda za doseganje ciljnega območja koncentracije glukoze v plazmi so lahko potrebni (za približno 10 do 18%) večji odmerki zdravila Toujeo.
• The Toujeo DoubleStar pen contains 900 units of Toujeo. 
• Peresnik Toujeo DoubleStar vsebuje 900 enot zdravila Toujeo.
To ensure the pen and needle are working, always perform the safety test until you see insulin coming out the needle tip before each injection (see STEP 3). 
Za preverjanje, da peresnik in igla delujeta, vedno pred vsakim injiciranjem opravite varnostni preizkus, dokler ne vidite, da je iz konice igle prišel insulin (glejte 3.
Before using Toujeo SoloStar pre-filled pen or Toujeo DoubleStar pre-filled pen, the instructions for use included in the package leaflet must be read carefully (see section 6.6). 
Pred uporabo napolnjenega injekcijskega peresnika Toujeo SoloStar ali napolnjenega injekcijskega peresnika Toujeo DoubleStar mora bolnik natančno prebrati navodilo za uporabo, navedena na priloženem navodilu za uporabo (glejte poglavje 6.6).
Table 3 - Summary of the hypoglycaemic episodes of the clinical study in patients with type 1 and type 2 diabetes mellitus 
Povzetek hipoglikemij v klinični študiji pri bolnikih s sladkorno boleznijo tipa 1 in tipa 2.
Packs of 1, 3, 6 (2 packs of 3), 9 (3 packs of 3) and 10 pre-filled pens. 
Na voljo so pakiranja z 1, 3, 6 (2 pakiranja po 3), 9 (3 pakiranja po 3) in 10 napolnjenimi injekcijskimi peresniki.
What you need to know before you use Toujeo Do not use Toujeo 
Kaj morate vedeti, preden boste uporabili zdravilo Toujeo
A Select 3 units by turning the dose selector until the dose pointer is at the mark between 2 and 
A Nastavite 3 enote tako, da zavrtite izbirnik odmerka, dokler kazalnik odmerka ne kaže oznake med 2 in 4.
The Toujeo SoloStar and Toujeo DoubleStar pre-filled pens have been specifically designed for Toujeo and no dose re-calculation is required for either pen. 
Napolnjeni injekcijski peresnik Toujeo SoloStar in Toujeo DoubleStar sta posebej izdelana za zdravilo Toujeo, zato odmerka ni treba preračunavati.
Tell a doctor straight away if you notice signs of a severe allergic reaction. 
Če opazite znake hude alergijske reakcije, morate o tem nemudoma obvestiti zdravnika.
PARTICULARS TO APPEAR ON THE OUTER PACKAGING OUTER CARTON Multipack (contains Blue Box) 
PODATKI NA ZUNANJI OVOJNINI ZUNANJA ŠKATLA skupnega pakiranja (vključuje podatke za modro okence)
• Change the place within the area you inject each day. 
• V predelu, kamor injicirate zdravilo, mesto injiciranja vsak dan menjajte.
Toujeo must not be administered intravenously. 
Zdravila Toujeo se ne sme dajati intravensko.
Plasma glucose reductions at the end of the trial with Toujeo were similar to insulin glargine 100 units/ml with a more gradual reduction during the titration period with Toujeo. 
Znižanja glukoze v plazmi so bila na koncu preskušanja z zdravilom Toujeo podobna kot z insulinom glargin 100 enot/ml, a s postopnejšim zniževanjem med obdobjem titriranja zdravila Toujeo.
• Diuretics - for high blood pressure or fluid retention. 
• Diuretike - za visok krvni tlak ali zastajanje tekočine v telesu.
Mild episodes of hypoglycaemia can usually be treated with oral carbohydrates. 
Blage hipoglikemije je po navadi mogoče obvladati z uživanjem ogljikovih hidratov.
What Toujeo looks like and contents of the pack 
Izgled zdravila Toujeo in vsebina pakiranja
Adjusted mean differenceb 
Korigirana povprečna razlikab
Results support the use of Toujeo in paediatric patients with type 2 diabetes mellitus. 
Rezultati podpirajo uporabo zdravila Toujeo pri otrocih s sladkorno boleznijo tipa 2.
Adjusted Mean change from baseline Adjusted Mean differenceb 
Korigirana povprečna sprememba od izhodišča Korigirana povprečna razlikab
To prevent possible transmission of disease, insulin pens should never be used for more than one person, even when the needle is changed (see section 6.6). 
Da bi preprečili možen prenos bolezni, se insulinski peresniki nikoli ne smejo uporabljati pri več kot eni osebi, tudi če se zamenja injekcijska igla (glejte poglavje 6.6).
In Toujeo clinical studies in adult patients, the incidence of allergic reactions was similar in Toujeo-treated patients (5.3%) and insulin glargine 100 units/ml-treated patients (4.5%). 
V kliničnih študijah pri odraslih bolnikih je bila incidenca alergijskih reakcij podobna pri bolnikih, zdravljenih z zdravilom Toujeo (5,3 %), in bolnikih, zdravljenih z insulinom glargin 100 enot/ml (4,5 %).
If you re-use a needle this increases the risk of it becoming blocked and of you getting too much or too little insulin. 
Igel nikdar ne uporabljajte ponovno - če iglo ponovno uporabite, to poveča tveganje, da se bo zamašila in da boste dobili preveč ali premalo insulina.
• Do not inject a double dose to make up for a forgotten dose. 
• Ne vzemite dvojnega odmerka, če ste pozabili injicirati prejšnji odmerek.
Figure 1 shows results from a cross-over study in 18 patients with type 1 diabetes conducted for a maximum of 36 hours after injection.The effect of Toujeo was beyond 24 hours (up to 36 hours) at clinically relevant doses. 
Slika 1 prikazuje rezultate navzkrižne študije pri 18 bolnikih s sladkorno boleznijo tipa 1, ki je potekala do največ 36 ur po injiciranju.
As with all insulins, the time course of action of insulin glargine may be affected by physical activity and other variables. 
Na časovni potek delovanja insulina glargin lahko vplivajo telesna dejavnost in drugi spremenljivi dejavniki, tako kot velja za vsa insulinska zdravila.
How to care for your pen Handle your pen with care 
Kako skrbeti za peresnik
Your blood sugar level may fall (hypoglycaemia) if you take: 
Krvni sladkor vam lahko pade (hipoglikemija), če jemljete:
Talk to your doctor before travelling. 
Pred potovanjem se posvetujte z zdravnikom - morda se boste morali posvetovati:
• Do not dial your dose by counting the clicks. 
• Ne nastavljajte odmerka s štetjem klikov, ki jih slišite.
Insulin glargine 100 units/ml and Toujeo are not bioequivalent and are not directly interchangeable. 
Insulin glargin 100 enot/ml in zdravilo Toujeo nista bioekvivalentna in nista medsebojno zamenljiva.
The half-life after subcutaneous administration of Toujeo is determined by the rate of absorption from the subcutaneous tissue. 
Razpolovni čas po subkutani uporabi zdravila Toujeo določa hitrost absorpcije iz podkožnega tkiva.
To prevent possible transmission of disease, insulin pen should never be used by for more than one person, even when the needle is changed (see section 4.2). 
Da bi preprečili možen prenos bolezni, se insulinski peresniki nikoli ne smejo uporabljati pri več kot eni osebi, tudi če se zamenja injekcijsko iglo (glejte poglavje 4.2).
Re-use of needles increases the risk of blocked needles which may cause underdosing or overdosing. 
Ponovna uporaba igel povečuje tveganje, da bo igla zamašena, to pa lahko povzroči preveliko ali premajhno odmerjanje.
Patients previously treated with basal insulin 
Bolniki, predhodno zdravljeni z bazalnim insulinom
Use only in this pen or severe overdose can result. 
Uporabite samo v tem injekcijskem peresniku, sicer lahko pride do hudega prevelikega odmerjanja.
• If you turn past your dose, you can turn back down. 
• Če zavrtite več, kot je vaš odmerek, lahko izbirnik odmerka zavrtite nazaj.
Toujeo is for subcutaneous use only. 
Zdravilo Toujeo je namenjeno samo za subkutano uporabo.
If you are breast-feeding, talk to your doctor, as your insulin doses and your diet might need to be changed. 
Če dojite, se posvetujte z zdravnikom, kajti morda bo treba prilagoditi odmerek insulina in prehrano.
5 pens 
5 sekund
When switching from a treatment regimen with an intermediate or long-acting insulin product to a regimen with Toujeo, a change of the dose of the basal insulin may be required and the concomitant anti-hyperglycaemic treatment may need to be adjusted. 
Pri prehodu s srednjedolgo- ali dolgodelujočega insulina na zdravljenje z zdravilom Toujeo sta lahko potrebni sprememba odmerka bazalnega insulina in prilagoditev sočasnih antihiperglikemičnih zdravil.
No significant difference was seen in the progression of diabetic retinopathy when insulin glargine100 units/ml was compared to NPH insulin. 
Primerjava napredovanja diabetične retinopatije ni pokazala značilne razlike med insulinom glargin 100 enot/ml in insulinom NPH.
Serious low blood sugar may cause brain damage and may be life-threatening. 
Resno znižanje krvnega sladkorja lahko povzroči okvaro možganov in je lahko smrtno nevarno.
Insulin glargine is a human insulin analogue designed to have a low solubility at neutral pH. At pH 4, insulin glargine is completely soluble. 
Insulin glargin je analog humanega insulina, pripravljen tako, da je pri nevtralnem pH slabo topen.
A Choose a place to inject as shown in the picture B Push the needle into your skin as shown by your doctor, pharmacist or nurse. 
B Zabodite iglo v kožo, kot vam je pokazal zdravnik, farmacevt ali medicinska sestra.