natgillin/translations-raw huggingface dataset:
The CVMP concurs with the representative of the MAHs that ‘the risk of fatal outcome as a result of an accidental injection/self-injection can be related to the following factors: dose, unrestrained animals, unprotected needles attached to a loaded syringe, working in isolation, the lack of accessible product information for emergency or health care professional to determine suitable treatments'. 
Odbor za zdravila za uporabo v veterinarski medicini (CVMP) se strinja s predstavnikom imetnikov dovoljenj za promet, da je „tveganje smrtnega izida kot posledice nenamernega injiciranja/samoinjiciranja povezano z naslednjimi dejavniki: odmerek, nezadržane živali, nezaščitene igle na napolnjeni brizgi, delo brez spremljevalcev, nedostopnost podatkov o zdravilu za osebje nujne medicinske pomoči in zdravstveno osebje, na podlagi katerih bi se lahko izbralo primerno zdravljenje“.
In pigs, intramuscular injection of 10 mg tilmicosin/kg caused increased respiration, emesis and convulsions; 20 mg/kg resulted in mortality in 3 of 4 pigs, and 30 mg/kg caused the death of all 4 pigs tested. 
Pri prašičih je intramuskularno injiciranje 10 mg tilmikozina/kg povzročilo pospešeno dihanje, bruhanje in krče; odmerek 20 mg/kg je povzročil smrt pri 3 od 4 prašičev, odmerek 30 mg/kg pa je povzročil smrt pri vseh 4 preskušanih prašičih.
Under paragraph 4.9 “Amounts to be administered and administration route” 
Pod točko 4.9 „Odmerjanje in način uporabe“
Restrain the animal and insert a separate needle subcutaneously into the injection site. 
Zadržite žival in subkutano uvedite drugo iglo na mesto injiciranja.
• Never carry a syringe loaded with Micotil with the needle attached. 
• Nikoli ne prenašajte brizge napolnjene z zdravilom Micotil in nameščeno iglo.
Injection in a fold of skin over the rib cage behind the shoulder is suggested. 
Priporoča se kožna guba nad rebri za pleči.
Netherlands Eli Lilly Nederland B.V. Postbus 379 
Nizozemska Eli Lilly Nederland B.V.
The needle should be connected to the syringe only when filling the syringe or administering the injection. 
Iglo namestite na brizgo samo pri polnjenju brizge ali injiciranju.
Other aspects relevant to the risk assessment include the fact that the use in cattle probably carries a higher risk of serious adverse effects in humans than would be the case in sheep due to the fact that adult cattle may be more physically threatening and the volumes used are higher. 
Pomemben vidik vrednotenja tveganja je dejstvo, da je z govedom povezano večje tveganje za hude neželene učinke pri človeku kot z ovcami, ker je odraslo govedo fizično bolj ogrožajoče in ker se za govedo uporabljajo večji volumni zdravila.
A number of risk management options considered by the CVMP are detailed below. 
V spodnjem besedilu so podrobno predstavljene možnosti upravljanja s tveganjem, o katerih je razpravljal CVMP.
Physicians treating patients exposed to this compound are advised to discuss clinical management with the National Poisons Information Service on: (indicate here the telephone number of the centre). 
Zdravnikom, ki zdravijo bolnike izpostavljene tej spojini, svetujemo, da se o kliničnem postopanju posvetujejo s Centrom za zastrupitve na: (telefonska številka Centra).
The use of a 2 ml or smaller syringe will facilitate accurate dosing. 
Natančnejše odmerjanje bo lažje z 2-mililitrsko ali manjšo brizgo.
- Clear warning that injection of the product in human beings has been associated with fatalities; - Instructions for safe use of the product (use different needles for loading a syringe and injecting into an animal, always uncouple syringe from needle during transport); - Instructions to properly restrain animals (the one treated and others in the vicinity); - Instructions never to work alone; - Recommendation to provide the physician with the vial or the package leaflet in case of accidental injection; - Note to the physician in the package leaflet and SPC detailing the known effects of Micotil in human beings, treatments to be avoided and substances that may partially counter certain effects of Micotil, including telephone numbers of national poison centres. 
- Jasno opozorilo, da je injiciranje tega zdravila v človeka povezano s smrtnimi primeri; - Navodila za varno uporabo zdravila (uporaba različnih igel za polnjenje brizge in injiciranje v žival, vedno sneti brizgo z igle med prenašanjem); - Navodila za ustrezno zadržanje živali (zdravljene živali in živali v bližini); - Navodilo, da mora biti pri dajanju zdravila prisotnih več oseb; - Priporočilo, da se zdravniku v primeru nenamernega injiciranja pokaže viala ali navodilo za uporabo; - Opomba zdravniku v navodilu za uporabo in SPC s podrobnostmi o znanih učinkih zdravila Micotil pri človeku, postopkih zdravljenja, katerim se je treba izogniti, in snoveh, ki delno zmanjšajo določene učinke zdravila Micotil, ter telefonskimi številkami nacionalnih centrov za zastrupitve.
The incidence of accidental injection or accidental self-injection of Micotil has also been estimated by the representative of the MAHs as 1.6 per million administrations, with an overall incidence of accidental exposure of a human being of 3 exposures per million administrations. 
Pojavnost nenamernega injiciranja ali nenamernega samoinjiciranja zdravila Micotil je ocenil tudi predstavnik imetnikov dovoljenj za promet na podlagi 1,6 milijona odmerjanj, pri čemer je bila ugotovljena skupna pojavnost nenamerne izpostavitve človeka 3 na milijon odmerjanj.
Such a volume restriction would necessitate additional administrations to the same animal. 
Zaradi takšne omejitve volumna bi bilo potrebno isti živali zdravilo dati večkrat.
- the Committee, having considered the referral question whether the wording with regard to the safety of users of the Micotil product literature should be harmonised in respect of a restriction to use by veterinary surgeons only, by majority considered that the condition of use be harmonised to ‘For use by veterinary surgeons only'; this condition was considered essential for the safe use of the veterinary medicinal product; 
- Odbor je po preučitvi vprašanja v napotitvi, ali naj se besedilo v zvezi z varnostjo uporabnikov v literaturi zdravila Micotil uskladi z omejitvijo uporabe na samo veterinarje, z večino ugotovil, da se pogoj za uporabo uskladi z besedilom ‘Zdravilo lahko uporablja samo veterinar'; ta pogoj se smatra kot ključen za varno uporabo zdravila za veterinarsko uporabo;
Pre-clinical data and an isolated clinical report suggest that calcium chloride infusion may help to reverse tilmicosin induced changes in blood pressure and heart rate in humans. 
Predklinični podatki in osamljeno klinično poročilo kažejo, da infundiranje kalcijevega klorida pri ljudeh lahko pripomore k spremembi induciranih sprememb krvnega tlaka in srčne frekvence.
Tilmicosin can cause fatalities in human beings following injection of high doses of the substance. 
Tilmikozin lahko pri človeku ob injiciranju velikih odmerkov povzroči smrt.
GROUNDS FOR AMENDMENT OF THE SUMMARY OF PRODUCT CHARACTERISTICS: 
PODLAGA ZA DOPOLNILO POVZETKA GLAVNIH ZNAČILNOSTI ZDRAVILA:
Appropriate educational measure targeted at users (veterinary surgeons and the agricultural community) would be undertaken by the MAHs. 
Ustrezne izobraževalne ukrepe za uporabnike (veterinarje in kmetijsko skupnost) bi jih izvedli imetniki dovoljenj za promet.
- the Committee, having considered the referral question whether the wording of the Micotil product literature should be harmonised with regard to the volume to deliver per syringe with regard to the safety of users, unanimously did not consider such a restriction to be an appropriate measure in order to ensure appropriate user safety throughout the EU; 
- Odbor je po preučitvi vprašanja v napotitvi, ali naj se besedilo v zvezi z varnostjo uporabnikov v literaturi zdravila Micotil uskladi glede volumna za injiciranje na brizgo, soglasno ugotovil, da takšna omejitev ni ustrezen ukrep za zagotovitev ustrezne varnost uporabnikov po EU;
By contrast it seems probable that the risk of non-fatal effects in humans following use in sheep would be higher than in cattle due to the fact that sheep require a lower dose and the product may be widely used in such animals. 
Zaradi tega se zdi, da je pri uporabi pri ovcah lahko večje tveganje nesmrtnih učinkov kot pri govedu, ker se za ovce uporabljajo manjši odmerki in ker je zdravilo široko uporabljeno za zdravljenje teh živali.
Connect the syringe to the needle and inject into the base of the skin fold. 
Namestite brizgo na iglo in vbrizgajte zdravilo v bazo kožne gube.
Improvements to the advice to physicians and access to appropriate medical information following poisoning are also likely to reduce the risk of severe effects as more effective hospital care might be available. 
Tveganje hudih učinkov se bi verjetno zmanjšalo z izboljšanjem nasvetov za zdravnike in dostopa do ustreznih zdravstvenih podatkov po zastrupitvi, saj bi verjetno bila nudena bolj učinkovita bolnišnična oskrba.
Overall risk assessment 
Skupna ocena tveganja
The CVMP did not consider it feasible or appropriate to recommend the re-formulation of the product to lower strength. 
Po mnenju CVMP priporočilo o reformulaciji zdravila v šibkejšo obliko ni izvedljivo ali primerno.
Under paragraph 4.5 “Special precautions for use” 
V odstavku 4.5 „Posebna opozorila in previdnostni ukrepi“
It must be noted that systems for properly recording suspected adverse reactions may not be in existence in every country in the world where the product is marketed. 
Pri tem je treba upoštevati, da v vseh državah na svetu, kjer se zdravilo trži, niso vzpostavljeni sistemi beleženja sumov neželenih reakcij.
Doses of 2-3 ml have been reported to induce adverse effects. 
Neželene učinke so povzročili odmerki 2-3 ml.
Single dose Sheep: 10 mg/kg bw 
En odmerek Ovce: 10 mg/kg TM
Belgium Eli Lilly Benelux Stoofstraat 52 
Eli Lilly Benelux Stoofstraat 52 1000 Brussels Belgija
A significant number of such users is likely to not fully understand the implications of the warnings and: o may not fully apply the measures intended to ensure their personal safety (i.e. the warning not to work alone is likely to be ignored; users may fail to detach the needle from the syringe containing the product and not fully understand the risks of accidental injection); o improperly store the product, potentially leading to easier availability for misuse and abuse; o may inappropriately use any product remaining following treatment of the original animal(s) at a later time point with consequential risks. 
Številni uporabniki verjetno ne bodo popolnoma razumeli pomembnosti opozoril in: o ne bodo popolnoma upoštevali ukrepov, ki so namenjeni njihovi osebni varnosti (tj. opozorilo, da mora biti pri dajanju zdravila prisotnih več oseb, bo verjetno prezrto; uporabniki morda ne bodo sneli igle iz brizge z zdravilom in popolnoma razumeli tveganja nenamernega injiciranja); o bodo nepravilno hranili zdravilo, kar bo potencialno povzročilo lažjo dostopnost za nepravilno uporabo in zlorabo; o bodo lahko kasneje neprimerno porabili zdravilo preostalo po zdravljenju prvotne(ih) živali s posledičnimi tveganji.
Pneumonia: 10 mg/kg bw Interdigital necrobacillosis: 5 mg/kg bw subcutaneous use 
Pljučnica: 10 mg/kg TM Interdigitalna nekrobaciloza: 5 mg/kg TM subkutana uporaba
PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGE IMMEDIATE (VIAL) LABEL - ALL AUTHORISED PACK SIZES 
PODATKI NA STIČNI OVOJNINI NALEPKA NA STEKLENIČKI - VSE ODOBRENE VELIKOSTI PAKIRANJA
They are trained for and used to appropriate storage of potentially lethal products. 
Usposobljeni so za shranjevanje potencialno smrtonosnih pripravkov in teh postopkov so tudi vajeni.
Tilmicosin is a macrolide antibiotic synthesized from tylosin which has an antibacterial spectrum similar to tylosin with enhanced activity against Pasteurella multocida and Pasteurella haemolytica. 
Spekter bakterij, proti katerim je tilmikozin učinkovit, je podoben tilozinu, vendar ima povečano aktivnost proti bakterijama Pasteurella multocida in Pasteurella haemolytica.
Administration of intravenous calcium chloride should only be considered if there is positive confirmation of exposure to tilmicosin. 
Uporabo intravenskega dajanja kalcijevega klorida preučite le po potrditvi izpostavitvi tilmikozinu.
In dog studies, tilmicosin induced a negative inotropic effect with consequent tachycardia, and a reduction in systemic arterial blood pressure and arterial pulse pressure. 
Raziskave pri psih so pokazale, da tilmikozin sproži negativni inotropni učinek in naknadno tahikardijo ter znižanje sistemskega arterijskega krvnega tlaka ter arterijskega utripnega tlaka.
Cattle (calf) 
Govedo (teleta)
Recommendation of harmonised, stringent EU user safety warnings including advice to the physician on appropriate treatment, and appropriate educational measures for users, without further restrictions 
Priporočilo o usklajenih obveznih varnostnih opozorilih za uporabnike v EU, vključno z nasveti za zdravnike o ustreznem zdravljenju ter ustreznih izobraževalnih ukrepih za uporabnike brez dodatnih omejitev
Additional operator safety warnings: 
Dodatna varnostna opozorila za osebo, ki daje zdravilo:
Recommendation of harmonised, stringent EU user safety warnings including advice to the physician on appropriate treatment, restriction of use to veterinary surgeons and other suitably qualified persons (as judged by the veterinary surgeons), and appropriate educational measures for users 
Priporočilo o usklajenih obveznih varnostnih opozorilih za uporabnike v EU, vključno z nasveti za zdravnike o ustreznem zdravljenju, omejitvi uporabe na veterinarje in druge ustrezno usposobljene osebe (po presoji veterinarjev) ter ustreznih izobraževalnih ukrepih za uporabnike
or E. coli, two bacteria often the focus of human food-borne illness concerns. 
Tilmikozin zlasti ni učinkovit proti vrstam iz rodu Salmonella in proti E. coli, dvema skupinama bakterij, ki pri človeku pogosto povzročajo bolezni preko živil.
Beta adrenergic antagonists such as propanolol exacerbated the negative inotrophy of tilmicosin in dogs. 
Zaviralci betaadrenergičnih receptorjev, kot je propanolol, pri psih stopnjujejo negativno inotropijo tilmikozina.
CaCl2 treatment showed a positive inotropic effect on the left ventricular inotropic state after tilmicosin administration in beagle dogs. 
Zdravljenje s CaCl2 je pokazalo pozitivni inotropni učinek na inotropno stanje levega prekata po dajanju tilmikozina psom pasme beagle.
Single dose 10 mg Tilmicosinum/ kg bw equivalent to 1 ml per 30 kg bw, during 3-4 days subcutaneous use. 
En odmerek 10 mg Tilmicosinum/kg TM enakovredno 1 ml na 30 kg TM, v 3-4 dneh subkutana uporaba.
Dobutamine partially offset the negative inotrophic effects induced by tilmicosin in dogs. 
Dobutamin pri psih delno kompenzira negativne inotropne učinke tilmikozina.
Recommendation of harmonised, stringent EU user safety warnings including advice to the physician on appropriate treatment, restriction of use to veterinary surgeons only, and appropriate educational measures for users 
Priporočilo o usklajenih obveznih varnostnih opozorilih za uporabnike v EU, vključno z nasveti za zdravnike o ustreznem zdravljenju, omejitvi uporabe na samo veterinarje ter ustreznih izobraževalnih ukrepih za uporabnike
Non-lactating sheep 
Ovce, ki niso v obdobju laktacije
Cattle, sheep and rabbit Single dose 10 mg tilmicosin/kg bw (1 ml/30 kg bw) subcutaneous use 
Govedo, ovce in kunci En odmerek 10 mg tilmikozina/kg TM (1 ml/30 kg TM) subkutana uporaba
Intravenous injection of 4.5 to 5.6 mg tilmicosin/kg followed by intravenous injection of 1 ml epinephrine (1/1000) 2 to 6 times resulted in death of all 6 injected pigs. 
Intravensko injiciranje od 4,5 do 5,6 mg tilmikozina/kg, kateremu je sledilo injiciranje 1 ml epinefrina (1/100) dva- do šestkrat, je povzročilo smrt pri vseh šestih prašičih, katerim so navedene pripravke injicirali.
Intraveneous injection of 4.5 and 5.6 mg tilmicosin/kg followed by intravenous injection of 1 ml epinephrine (1/1000) 2 to 6 times resulted in death of all 6 injected pigs. 
Intravensko injiciranje 4,5 in 5,6 mg tilmikozina/kg, kateremu je sledilo injiciranje 1 ml epinefrina (1/100) dva- do šestkrat, je povzročilo smrt pri vseh šestih prašičih, katerim so navedene pripravke injicirali.
Bovine 
Govedo
INJECTION OF THIS DRUG IN HUMANS CAN BE FATAL - EXERCISE EXTREME CAUTION TO AVOID ACCIDENTAL SELF-INJECTION AND FOLLOW THE ADMINISTRATION INSTRUCTIONS AND THE GUIDANCE BELOW, PRECISELY 
INJICIRANJE TEGA ZDRAVILA LAHKO PRI ČLOVEKU POVZROČI SMRTBODITE ZELO PREVIDNI, DA PREPREČITE NENAMERNO SAMOINJICIRANJE.
In pigs, tilmicosin-induced lethality is potentiated by adrenalin. 
Pri prašičih adrenalin poveča s tilmikozinom povzročeno smrtnost.
THE WORDS “FOR ANIMAL TREATMENT ONLY” AND CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE 
ODMEREK ZA POSAMEZNE ŽIVALSKE VRSTE TER NAČIN UPORABE IN DAJANJA ZDRAVILA
• This product should only be administered by a veterinary surgeon. 
• To zdravilo lahko daje samo veterinar.
In dogs, treatment with intravenous calcium chloride showed a positive effect on the left ventricular inotropic state and some improvements in vascular blood pressure and tachycardia. 
Pri psih je intravensko dajanje kalcijevega klorida pokazalo pozitivni učinek na inotropno stanje levega prekata ter določeno izboljšanje žilnega krvnega tlaka in tahikardije.
Pigs given 4.5 to 5.6 mg tilmicosin/kg intravenously with no epinephrine all survived. 
Vsi prašiči, katerim so intravensko dali od 4,5 do 5,6 mg tilmikozina/kg brez epinefrina, so preživeli.
Pigs given 4.5 and 5.6 mg tilmicosin/kg intravenously with no epinephrine all survived. 
Vsi prašiči, katerim so intravensko dali 4,5 in 5,6 mg tilmikozina/kg brez epinefrina, so preživeli.
0.5 - 1ml Micotil per 30 kg bw (equivalent to 5-10mg tilmicosin per kg bw) subcutaneous use 
0,5 - 1 ml zdravila Micotil na 30 kg TM, (enakovredno 5-10 mg tilmikozina na kg TM) subkutana uporaba
In one experiment isolated human cardiac atrial myocites were used to study the L-type Ca channel blocking profile. 
V enem poskusu preučili profil blokiranja Ca-kanalčkov tipa L na izoliranih atrijskih miocitih iz človeškega srca.
Recommended dose Route of administration 
Priporočeni odmerek Način uporabe zdravila
1ml Micotil per 30 kg bw (equivalent to 10mg tilmicosin per kg bw). 
1 ml zdravila Micotil na 30 kg TM, (enakovredno 10 mg tilmikozina na kg TM).
METHOD AND ROUTE OF ADMINISTRATION 
NAČIN UPORABE IN DAJANJA
Operator Safety Warnings: 
Varnostna opozorila za osebo, ki daje zdravilo:
Single dose 1 ml/30 kg bw subcutaneous use 
En odmerek 1 ml/30 kg TM subkutana uporaba
For animal treatment only to be supplied only on veterinary prescription. 
Uporablja se le na osnovi recepta veterinarja.
• In case of human injection SEEK IMMEDIATE MEDICAL ATTENTION and take this vial or the package leaflet with you. 
• V primeru injiciranja v človeka NEMUDOMA POIŠČITE ZDRAVNIŠKO POMOČ in s sabo vzemite to navodilo ali vialo.
However, the fact that the attending veterinary surgeon needs to ascertain the competence of the user, with both parties signing a form, is likely to minimise the risk of failure of this part of the measures; - While with this option the users of Micotil are more likely to understand the implications of the recommended warnings, a risk, though arguably lower than for option number 3, remains that: o the recommended measures intended to ensure their personal safety are not fully applied (i.e. the warning not to work alone is likely to be ignored; users may fail to detach the needle from the syringe containing the product and not fully understand the risks of accidental injection); o the product is not stored properly, potentially leading to easier availability for misuse and abuse; o any product remaining following treatment of the original animal(s) may be inappropriately used at a later time point with consequential risks. 
Ker pa bo moral pristojni veterinar ugotoviti usposobljenost uporabnika, pri čemer bosta morali obe strani podpisati obrazec, je verjetno, da bo prišlo do zmanjšanja tveganja neuspeha tega dela ukrepov na najmanjšo raven; - Čeprav bodo v okviru te možnosti uporabniki zdravila Micotil bolj verjetno razumeli posledice priporočenih opozoril, še vedno obstaja tveganje, čeprav verjetno manjše od možnosti številka 3, da:
Single dose 10 mg tilmicosin per kg bw, corresponding to 1 ml Micotil 300 per 30 kg bw subcutaneous use 
En odmerek 10 mg tilmikozina na kg TM, enakovredno 1 ml zdravila Micotil 300 na 30 kg TM
Single dose 1 ml Micotil 300 per 30 kg bw (10 mg tilmicosin/kg bw) subcutaneous use 
En odmerek 1 ml zdravila Micotil 300 na 30 kg (10 mg tilmikozina/kg TM) subkutana uporaba
Single dose 10 mg tilmicosin per kg bw (1ml per 30 kg bw) subcutaneous use 
En odmerek 10 mg tilmikozina na kg TM (1 ml na 30 kg TM) subkutana uporaba
In dogs, CaCl2 treatment showed a positive effect on the left ventricular inotrophic state after tilmicosin administration and some changes in vascular blood pressure and heart rate. 
Pri psih je zdravljenje s CaCl2 po dajanju tilmikozina pokazalo pozitivni učinek na inotropno stanje levega prekata ter nekaj sprememb v žilnem krvnem tlaku in srčni frekvenci.
• In case of human injection SEEK IMMEDIATE MEDICAL ATTENTION and take the vial or the package leaflet with you. 
• V primeru injiciranja v človeka NEMUDOMA POIŠČITE ZDRAVNIŠKO POMOČ in s sabo vzemite vialo ali navodilo.
Single dose 1 ml for 30 kg bw (i.e. 10 mg of tilmicosin/kg bw) subcutaneous use 
En odmerek 1 ml na 30 kg TM (tj. 10 mg tilmikozina/kg TM) subkutana uporaba
The withdrawal of Micotil from the market in the EU has been considered in the risk analysis conducted by the CVMP and would reduce the risk of human fatalities or any human adverse reactions to zero. 
V analizi tveganja je CVMP obravnaval umik zdravila Micotil iz prometa v EU.
- the Committee unanimously considered it necessary that the user safety warnings for the products concerned be harmonised throughout the EU in order to ensure appropriate user safety, in consideration of the referral question whether the wording with regard to the safety of users of the Micotil product literature should be harmonised; 
- Odbor je po preučitvi vprašanja v napotitvi, ali naj se besedilo v zvezi z varnostjo uporabnikov v literaturi zdravila Micotil uskladi, soglasno ugotovil, da je nujno uskladiti varnostna opozorila za zadevno zdravilo po vsej EU, da se zagotovi ustrezno varnost uporabnikov.
Single dose 10 mg/kg bw subcutaneous use 
En odmerek 10 mg/kg TM subkutana uporaba
Single dose 10 mg tilmicosin/kg bw subcutaneous use 
En odmerek 10 mg tilmikozina/kg TM subkutana uporaba
This overview was last updated in February 2018. 
Povzetek je bil nazadnje posodobljen februarja 2018.
Further information on Clevor can be found on the Agency's website: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports. 
Več informacij o zdravilu Clevor je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Veterinary medicines/European public assessment reports.
The European Medicines Agency decided that Clevor's benefits are greater than its risks and it can be authorised for use in the EU. 
Evropska agencija za zdravila je odločila, da so koristi zdravila Clevor večje od z njim povezanih tveganj in da se lahko odobri za uporabo v EU.
Other information about Clevor 
Druge informacije o zdravilu Clevor
Three dogs did not vomit at all despite a second dose. 
Trije psi kljub drugemu odmerku niso bruhali.
If the dog does not vomit within 15 minutes of treatment, treatment may be repeated. 
Če pes v 15 minutah po zdravljenju ne bruha, se mu lahko zdravilo da ponovno.
Clevor received a marketing authorisation valid throughout the EU on 13 April 2018. 
Zdravilo Clevor je pridobilo dovoljenje za promet, veljavno po vsej Evropski uniji, 13/04/2018.
In a field trial involving 132 healthy dogs which compared Clevor with placebo (dummy treatment), 95% of the dogs vomited within 30 minutes. 
V terenskem preskušanju, ki je vključevalo 132 zdravih psov, v njem pa so primerjali zdravilo Clevor s placebom (zdravilom brez zdravilne učinkovine), je 95 % psov bruhalo v 30 minutah.