natgillin/translations-raw huggingface dataset:
Before initiating treatment with Ruconest, patients should be queried about prior exposure to rabbits and signs and symptoms suggestive of an allergic reaction. 
Pred uvedbo zdravljenja z zdravilom Ruconest je treba bolnike izprašati o predhodni izpostavljenosti kuncem ter o znakih in simptomih, ki kažejo na alergijsko reakcijo.
An aseptic technique should be used for reconstitution, combining and mixing the solutions. 
Za rekonstitucijo, kombiniranje in mešanje raztopine je treba uporabiti aseptično tehniko.
In case of anaphylactic reactions or shock, emergency medical treatment should be administered. 
V primeru anafilaktičnih reakcij ali šoka je treba nuditi nujno medicinsko pomoč.
In an open label study 114/119 (95%) attacks treated with a single dose of 50 U/kg reached time to beginning of relief within 4 hours. 
V odprti študiji je 114/119 (95 %) napadov, zdravljenih z enim odmerkom 50 e./kg, doseglo čas ublažitve v 4 urah.
The table below lists all adverse reactions occurring within 7 days after treatment with Ruconest, as reported in the six treatment studies. 
Spodnja preglednica zajema vse neželene učinke, ki so se pojavili v 7 dneh po zdravljenju z zdravilom Ruconest, na podlagi poročil v šestih študijah zdravljenja.
• After disinfection, do not touch the stoppers with your fingers or anything else. 
• Po razkuževanju se zapork ne dotikajte s prsti ali katerimi koli drugimi predmeti.
Inform your healthcare professional if this occurs. 
V tem primeru obvestite zdravstveno osebje.
After swirling, leave the vial on the surface for several minutes until the solution has become clear. 
Po vrtenju vialo nekaj minut pustite na delovni površini, dokler se raztopina ne zbistri.
• 2 alcohol pads 
• 2 alkoholni blazinici
• If you are or think you are allergic to rabbits • If you are allergic to conestat alfa or any of the other ingredients of this medicine (listed in section 6). 
• če ste alergični na konestat alfa ali katero koli sestavino zdravila (navedeno v poglavju 6).
What you need to know before you use Ruconest Do not use Ruconest: 
Kaj morate vedeti, preden boste uporabili zdravilo Ruconest Ne uporabljajte zdravila Ruconest:
Your dose, up to 2 vials, will be worked out based on your weight. 
Odmerek, do 2 viali naenkrat, se izračuna na podlagi vaše telesne mase.
Dose calculation 
Izračun odmerka
• Check whether the powder in the vial(s) has dissolved completely and the plunger is completely pushed down in the syringe. 
• Preverite, ali se je prašek v viali oz. vialah popolnoma raztopil in da je bat brizge potisnjen do konca.
The expiry date on the outer carton reflects the date of the component with the shortest shelf-life. 
Datum izteka roka uporabnosti, naveden na zunanji ovojnini (škatli), navaja datum komponente z najkrajšim rokom uporabnosti.
Contents of the pack and other information What Ruconest contains 
Vsebina pakiranja in dodatne informacije Kaj vsebuje zdravilo Ruconest
In one animal study reproductive toxicity was observed (see section 5.3). 
Ena študija na živalih je pokazala vpliv na sposobnost razmnoževanja (glejte poglavje 5.3).
• Take the syringe with solvent that you prepared in step 4. 
• Vzemite brizgo z vehiklom, ki ste jo pripravili v 4. koraku.
Repeat steps 3 and 4 if you need to prepare a second solution (this requires a second kit). 
Če je treba pripraviti še eno raztopino, ponovite 3. in 4. korak (za kar potrebujete drugo pakiranje).
Determine the patient's body weight. 
Ugotovite telesno maso bolnika.
The MAH shall perform the pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any agreed subsequent updates of the RMP. 
• Načrt za obvladovanje tveganja (RMP) Imetnik dovoljenja za promet z zdravilom bo izvedel zahtevane farmakovigilančne aktivnosti in ukrepe, podrobno opisane v sprejetem RMP, predloženem v modulu 1.8.2 dovoljenja za promet z zdravilom, in vseh nadaljnjih sprejetih posodobitvah RMP.
• Diary to be given to patients before they receive Ruconest. 
• Dnevnik, ki ga je treba dati bolniku, preden prejme zdravilo Ruconest.
• Allow the number of powder and solvent vials required according to step 1, to reach room temperature. 
• Pustite, da potrebno število vial s praškom in vial z vehiklom, zahtevanih v 1. koraku, doseže sobno temperaturo.
• That they should be asked to carry the card and always show it to any Healthcare Professional treating them for acute attacks of hereditary angioedema. 
• Opozorilo, naj imajo opozorilno kartico pri sebi in jo vedno pokažejo vsakemu zdravstvenemu delavcu, ki jih zdravi zaradi akutnih napadov dednega angioedema.
Although cross-reactivity between cow milk and rabbit milk is considered unlikely, the possibility of such a cross-reactivity in a patient who has evidence of clinical allergy to cow milk cannot be excluded and the patient should be observed for signs and symptoms of hypersensitivity following Ruconest administration. 
Čeprav je navzkrižna reaktivnost med kravjim in kunčjim mlekom malo verjetna, pri bolnikih, pri katerih je dokazana klinična alergija na kravje mleko, takih navzkrižnih reakcij ni možno izključiti in je bolnika po dajanju zdravila Ruconest treba opazovati glede znakov in simptomov preobčutljivosti.
Do not mix or administer Ruconest with other medicines or solutions. 
Zdravila Ruconest ne mešajte ali dajajte z drugimi zdravili ali raztopinami.
administered (ml) = body weight (kg) times 50 (U/kg) 150 (U/ml) 
= telesna masa (kg) krat 50 (e./kg) 150 (e./ml)
- Information on the need to keep a diary to document each treatment administered at home and to bring it at each visit. 
- Informacije o potrebi pisanja dnevnika za dokumentiranje vsakega odmerka, danega doma, in predložitev tega dnevnika pri vsakem zdravniškem pregledu.
No more than 2 doses should be given within 24 hours. 
V 24 urah se ne sme dati več kot dva odmerka.
• Check that all required components are on the work surface: - 1 or 2 syringes with prepared solution - 1 infusion set with 25G needle - 1 alcohol pad - 1 sterile non-woven pad - 1 self-adhesive plaster - 1 tourniquet - 1 plaster for securing the needle 
• Preverite, da so na delovni površini vse potrebne komponente: - 1 ali 2 brizgi s pripravljeno raztopino - 1 komplet za infundiranje z iglo 25G - 1 alkoholna blazinica - 1 sterilni netkani tampon - 1 samolepilni obliž - 1 žilna preveza - 1 obliž za pritrditev igle
Never exceed 14 ml per syringe. 
Nikoli ne presezite 14 ml na brizgo.
Pack size of 1. 
Velikost pakiranja 1 viala.
• 1 infusion set with 35 cm tubing and 25G needle 
• 1 komplet za infundiranje s 35 cm cevko in iglo 25 G
• The potential risk of an immune complex-mediated type III hypersensitivity reaction due to the formation of antibodies directed against Host Related Impurities (HRI). 
• Morebitno tveganje preobčutljivostne reakcije tipa III, povzročene z imunskimi kompleksi, zaradi tvorbe protiteles proti nečistotam, povezanim z gostiteljem (HRI).
If you experience allergic reactions e.g. hives, rash, itching, dizziness, wheezing, difficulty breathing or your tongue swells up following the administration of Ruconest, you should seek emergency medical assistance so that symptoms of your allergic reaction can be treated urgently. 
Če imate alergijske reakcije, tj. koprivnico, izpuščaje, srbenje, vrtoglavico, hropenje, težave pri dihanju ali vaš jezik oteče po dajanju zdravila Ruconest, morate poiskati nujno medicinsko pomoč, da se lahko simptome vaše alergijske reakcije nemudoma zdravi.
• Leave the remainder of the solvent in the vial and discard the vial. 
• Preostali vehikel pustite v viali in jo zavrzite.
Before Ruconest can be administered, the powder needs to be dissolved in the solvent included in the package (see section 3). 
Pred injiciranjem zdravila Ruconest se mora prašek popolnoma raztopiti v vehiklu, priloženem v pakiranju (glejte poglavje 3).
Gently inject the solution of the second syringe. 
Nežno injicirajte raztopino druge brizge.
However headache or vertigo have been reported following the use of Ruconest, but may also occur as a result of an attack of HAE. 
Vendar pa so po uporabi zdravila Ruconest poročali o glavobolu ali vrtoglavici, ki pa se lahko pojavita tudi zaradi napada HAE.
The plasma protein C1INH is the main regulator of activation of the contact and complement systems in vivo. 
Plazemska beljakovina C1INH je glavni uravnalec aktivacije sistemov kontakta in komplementa in vivo.
Ruconest is intended for intravenous administration after reconstitution with water for injections. 
Zdravilo Ruconest je namenjeno za intravenozno uporabo po rekonstituciji z vodo za injekcije.
• After the powder has dissolved, the solution should be clear and colourless. 
• Ko se prašek raztopi, mora biti raztopina bistra in brezbarvna.
Do not remove the adapter packaging. 
Ne odstranite embalaže adapterja.
Emergency medical treatment should be available immediately to be administered in case of anaphylactic reactions or shock. 
Na voljo mora biti takojšnja nujna medicinska pomoč za primer anafilaktične reakcije ali šoka.
• That patients with clinical evidence of cow's milk allergy may have antibodies cross reacting with the rabbit milk impurities in Ruconest. 
• Da imajo lahko bolniki s klinično dokazano alergijo na kravje mleko protitelesa, ki povzročijo navzkrižno reakcijo z nečistotami kunčjega mleka v zdravilu Ruconest.
• Disinfect the injection site thoroughly with an alcohol pad and let the skin dry. 
• Mesto injiciranja dobro razkužite z alkoholno blazinico in pustite, da se koža osuši.
Embryofetal studies in rat and rabbit; Daily single doses of vehicle or 625 U/kg/administration of rhC1INH were administered intravenously to mated rats and rabbits. 
Študije razvoja zarodka/plodu pri podganah in kuncih; enkratni dnevni odmerek vehikla ali 625 e./kg rhC1INH sta bila dana intravensko podganam in kuncem v obdobju parjenja.
In HAE patients, Ruconest at a dose of 50 U/kg increases plasma C1INH activity level to greater than 0.7 U/ml for approximately 2 hours (see section 5.2). 
Pri bolnikih s HAE zdravilo Ruconest v odmerku 50 e/kg poveča raven aktivnosti C1INH v plazmi na raven, višjo od 0,7 e/ml, za približno 2 uri (glejte poglavje 5.2).
Ruconest is supplied in a carton box containing one vial. 
Zdravilo Ruconest je na voljo v kartonski škatli, ki vsebuje eno vialo.
• 1 vial of 20 ml solvent 
• 1 vialo z 20 ml vehikla
Do not remove the syringe packaging. 
Ne odstranite embalaže brizge.
• Hold the adapter with one hand. 
• Z eno roko držite adapter.
Disinfect the injection site with an alcohol pad. 
Mesto injiciranja razkužite z alkoholno blazinico.
Fertility There are no data on the effects of Ruconest on male or female fertility. 
O učinkih zdravila Ruconest na moško ali žensko plodnost ni podatkov.
How to use Ruconest 
Kako uporabljati zdravilo Ruconest
Ruconest is indicated for treatment of acute angioedema attacks in adults and adolescents with hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency. 
Zdravilo Ruconest je indicirano za zdravljenje akutnih napadov angioedema pri odraslih in mladostnikih s hereditarnim (dednim) angioedemom (HAE: Hereditary Angioedema) zaradi pomanjkanja zaviralca esteraze C1.
The amino acid sequence of conestat alfa is identical to that of endogenous C1INH. 
Aminokislinsko zaporedje konestata alfa je identično zaporedju endogenega C1INH.
HAE patients have a heterozygous deficiency of the plasma protein C1INH. 
Bolniki s HAE imajo heterozigotno pomanjkanje plazemske beljakovine C1INH.
• Put the vial adapters on the work surface. 
• Adapterje za viale položite na delovno površino.
This should be taken into consideration by patients on a controlled sodium diet. 
To morajo upoštevati bolniki, ki so na dieti za nadzorovanim vnosom natrija.
Tabulated lists of adverse reactions 
Tabelarični seznam neželenih učinkov
Never use any kit component after the expiry date stated on the big outer carton. 
Nobene komponente v kompletu ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na zunanji ovojnini (veliki škatli).
• Put the powder and solvent vials required on a flat and clean surface. 
• Potrebne viale s praškom in vehiklom položite na ravno in čisto površino.
The educational material for the Healthcare Professional should include information on the following key elements: 
Izobraževalno gradivo za zdravstvene delavce mora vsebovati informacije o naslednjih ključnih elementih:
• Leave the syringe on the adapter and gently swirl the vial for approximately half a minute. 
• Brizgo pustite pritrjeno na adapter in nato približno pol minute nežno vrtite vialo.
1 Unit of conestat alfa activity is defined as the equivalent of C1 esterase inhibiting activity present in 1 ml of pooled normal plasma. 
1 enota konestata alfa je opredeljena kot enakovredna zaviralni aktivnosti esteraze C1 v 1 ml zlitja normalne plazme.
• Feel, with your other hand, for an appropriate vein. 
• Z drugo roko zatipajte ustrezno žilo.
• Ensure the kit package is complete and contains all components listed in section 6 of this leaflet. 
Preden začnete • Prepričajte se, da je ovojnina celovita in vsebuje vse komponente, navedene v 6. poglavju teh navodil za uporabo.
Continue to fill the syringe with 14 ml solvent. 
Nadaljujte s polnjenjem brizge s 14 ml vehikla.
The reconstituted solution in each vial should be visually inspected for particulate matter and discoloration. 
Rekonstituirano raztopino v vsaki viali je treba vizualno pregledati glede trdnih delcev in spremembe barve.
• The need to inform patients about the early signs of hypersensitivity reactions including hives, generalised urticaria, tightness of the chest, wheezing, hypotension and anaphylaxis, and that they should alert their physician if these symptoms occur. 
• Obveznost informiranja bolnika o zgodnjih znakih preobčutljivostnih reakcij, ki vključujejo koprivnico, splošno urtikarijo, stiskanje v prsih, hropenje, hipotenzijo in anafilakso, in da morajo na te simptome opozoriti svojega zdravnika, če se pojavijo.
• Check that no air is present in the syringe, infusion tube or the needle. 
• Preverite, da v brizgi, cevki za infundiranje ali igli ni zraka.
• In addition to the kit, the following is required: - a tourniquet - plaster for securing the needle 
• Poleg kompleta potrebujete še: - žilno prevezo - obliž za pritrditev igle
Ruconest is administered into a vein over about 5 minutes. 
Zdravilo Ruconest se injicira v veno približno 5 minut.
Ruconest must be administered by a healthcare professional until the patient (or caregiver) is competent to administer after having been properly trained and in agreement with the healthcare professional. 
Zdravilo Ruconest mora dajati zdravstveni delavec, dokler bolnik (ali skrbnik) po ustreznem usposabljanju in v dogovoru z zdravstvenim delavcem ni zadostno usposobljen za samostojno dajanje.
• Draw in the volume of prepared solution, while keeping the syringe in the vertical position. 
• Izsesajte količino pripravljene raztopine, pri čemer naj bo brizga v navpičnem položaju.
Preclinical data do not indicate any safety concern for the use of conestat alfa in humans based on studies of safety pharmacology, single-dose toxicity, two-week sub-chronic toxicity and local tolerance in various animal species including rats, dogs, rabbits and cynomolgus monkeys. 
Predklinični podatki na osnovi običajnih študij farmakološke varnosti, toksičnosti enkratnega odmerka, dvotedenske subkronične toksičnosti in lokalne tolerance pri različnih živalskih vrstah, vključno s podganami, psi, kunci in javanskimi makaki, ne kažejo posebnega tveganja za človeka.
• Carefully pull back the syringe plunger slightly until you see blood being drawn into the tubing, to ensure that the needle is in the vein. 
• Previdno rahlo povlecite bat brizge, dokler v cevki ne zagledate krvi, s tem se boste prepričali, da je igla v žili.
• Abdominal pain, diarrhoea, nausea 
• Bolečine v trebuhu, diareja, slabost
The patient card should contain the following key elements: 
Opozorilna kartica za bolnika mora vsebovati naslednje ključne elemente:
For patients of 84 kg or above the volume required to be administered is 28 ml, corresponding to 4200 U (2 vials). 
Za bolnike s telesno maso 84 kg ali več je potrebni volumen za dajanje 28 ml, kar ustreza 4200 e. (2 viali).
If you plan becoming pregnant, discuss with your doctor before starting to use Ruconest. 
Če načrtujete zanositev, se posvetujte z zdravnikom, preden vzamete to zdravilo.
No dose adjustment is necessary in patients with renal impairment since conestat alfa does not undergo renal clearance. 
Pri bolnikih z ledvično okvaro ni potrebna prilagoditev odmerka, saj se konestat alfa ne izloča prek ledvic.
- Body weight up to 84 kg 
- Telesna masa do 84 kg
The medicinal product should be used immediately. 
Zdravilo je treba takoj uporabiti.
• The fact that Ruconest is derived from milk of transgenic rabbits and contains trace of rabbit proteins (Host Related Impurities, HRI). 
• Dejstva, da se zdravilo Ruconest pridobiva iz mleka transgenskih kuncev in vsebuje sledove kunčjih beljakovin (nečistote, povezane z gostiteljem: HRI - Host Related Impurities).
• There are limited data on the use of this medicinal product in home or self-administration. 
• Podatkov o uporabi tega zdravila pri zdravljenju doma ali samostojnem dajanju je malo.
Some side effects may occur during treatment with Ruconest: Common: may affect up to 1 in 10 people 
Med zdravljenjem z zdravilom Ruconest se lahko pojavijo nekateri neželeni učinki: Pogosti (pojavijo se lahko pri največ 1 od 10 bolnikov):
Step 11: Preparing the injection site 
11. korak: Priprava mesta za injiciranje
Do not use this medicine after the expiry date which is stated on the carton and on the label of the vial after EXP. 
Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli in na oznaki viale poleg oznake EXP. Rok uporabnosti zdravila se izteče na zadnji dan navedenega meseca.
The administration of Ruconest is to resolve the shortage of C1 inhibitor and will lead to reduction of symptoms of an acute attack of HAE. 
Z dajanjem zdravila Ruconest odpravimo pomanjkanje zaviralca C1 in zmanjšamo simptome akutnega napada angioedema.
Do not drive or use machinery if you feel dizzy or suffer from headache after using Ruconest. 
Ne vozite avtomobila ali upravljajte z orodji ali stroji, če imate po uporabi zdravila Ruconest vrtoglavico ali glavobol.
• the batch number written on the label of the powder vial 
• številko serije na nalepki viale s praškom
Inject the Ruconest solution immediately after preparation, preferably while seated. 
Raztopino zdravila Ruconest injicirajte nemudoma po pripravi, če je mogoče, v sedečem položaju.
Conestat alfa is derived from milk of transgenic rabbits and contains traces of rabbit protein. 
Konestat alfa je pridobljen iz mleka transgenskih kuncev in vsebuje sledove kunčjih beljakovin.
• Hives and swelling of the skin. 
• Koprivnica in otekanje kože.
• Carefully remove the plaster for securing the needle and withdraw the needle from the vein. 
• Previdno odstranite obliž za pritrditev igle in jo odstranite iz žile.
Ruconest must be administered by a healthcare professional until you or your caregiver are properly trained and capable to administer Ruconest. 
Zdravilo Ruconest mora dajati zdravstveni delavec, dokler vi ali vaš skrbnik niste zadostno usposobljeni in zmožni za dajanje zdravila Ruconest.
1 powder vial 1 solvent vial 2 vial adapters 1 syringe 
1 vialo s praškom 1 vialo z vehiklom 2 adapterja za viale 1 brizgo
In the majority of cases a single dose of Ruconest is sufficient to treat an acute angioedema attack. 
V večini primerov za zdravljenje akutnega napada angioedema zadostuje en odmerek zdravila
Very common (≥1/10), Common (≥1/100 to <1/10), Uncommon (≥1/1,000 to <1/100), Rare (≥1/10,000 to <1/1,000), 
Pogostnost neželenih učinkov v nadaljevanju je opredeljena v skladu z naslednjo klasifikacijo: zelo pogosti (≥1/10), pogosti (≥1/100 do <1/10), občasni (≥1/1.000 do <1/100), redki (≥1/10.000 do <1/1.000),
Based on animal data, conestat alfa is cleared from the circulation by the liver via receptor-mediated endocytosis followed by complete hydrolysis/degradation. 
Na podlagi podatkov študij na živalih se konestat alfa očisti iz krvnega obtoka s presnovo v jetrih z od receptorja odvisno endocitozo, ki ji sledi popolna hidroliza/razgradnja.
Home-treatment and self-administration 
Zdravljenje doma in samostojno dajanje
If air bubbles appear, minimise as far as possible by gently tapping the syringe and applying gentle pressure by pushing the plunger into the syringe. 
Če se pojavijo mehurčki, jih poskusite čim bolj omejiti z nežnim trepljanjem brizge in nežnim pritiskanjem bata v brizgo.
• That patients treated with Ruconest should be monitored for clinical signs and symptoms of hypersensitivity during administration. 
• Da je treba bolnike, zdravljene z zdravilom Ruconest, med dajanjem spremljati glede preobčutljivostnih kliničnih znakov in simptomov.
Patients should be informed of the early signs of hypersensitivity reactions including hives, generalised urticaria, tightness of the chest, wheezing, hypotension and anaphylaxis. 
Bolnike je treba poučiti o zgodnjih znakih preobčutljivostnih reakcij, ki vključujejo koprivnico, generalizirano urtikarijo, stiskanje v prsih, hropenje, hipotenzijo in anafilakso.
- Body weight up to 84 kg For patients up to 84 kg calculate the volume required to be administered according to the formula below: 
- Telesna masa do 84 kg Za bolnike s telesno maso do 84 kg izračunajte potrebni volumen v skladu s spodnjo preglednico:
• It is the responsibility of the physician to provide the patient or a caregiver with instructions and training on administration outside of a clinic setting. 
• Zdravnik mora bolnika ali njegovega skrbnika poučiti in usposobiti za dajanje zdravila zunaj bolnišnične ustanove.
• Turn the whole - solvent vial with adapter and syringe - upside down. 
• Celotni sestav - vialo z vehiklom, adapter in brizgo - obrnite na glavo.
Ruconest should be administered by a healthcare professional. 
Zdravilo Ruconest mora dati zdravstveni delavec.
It is not recommended to use Ruconest during pregnancy or breast-feeding. 
Uporaba zdravila Ruconest med nosečnostjo ali dojenjem ni priporočena.
• Immediately after removing the needle, press the sterile pad on the injection site for a few minutes to reduce bleeding. 
• Takoj po odstranitvi igle na mesto injiciranja pritisnite sterilni tampon in ga držite nekaj minut,
1 infusion set with needle 2 alcohol pads 1 sterile non-woven pad 1 adhesive plaster 
1 komplet za infundiranje z iglo 2 alkoholni blazinici 1 sterilni netkani tampon 1 obliž
After administration of Ruconest (50 U/kg) to asymptomatic HAE patients, a Cmax of 1.36 U/ml was observed. 
Po dajanju zdravila Ruconest (50 e./kg) asimptomatičnim bolnikom s HAE so izmerili Cmaks 1,36 e./ml.
- bodyweight 42 kg or less: 1 powder and 1 solvent vial - bodyweight over 42 kg: 2 powder and 2 solvent vials 
- telesna masa do 42 kg: 1 viala s praškom in 1 viala z vehiklom - telesna masa nad 42 kg: 2 viali s praškom in 2 viali z vehiklom
• It is the responsibility of the physician to verify that all the necessary skills have been acquired by the non-Healthcare Professional and that Ruconest may be safely and effectively administered outside of a Healthcare Professional setting. 
• Zdravnik je dolžan preveriti, da je nezdravstveni delavec razvil vse potrebne spretnosti ter da je omogočeno varno in učinkovito dajanje zdravila Ruconest zunaj zdravstvene ambulante.
Step 3: Mounting of adapters on vials 
3. korak: Namestitev adapterjev na viale
Conestat alfa, recombinant human complement component 1 (C1) esterase inhibitor (rhC1INH), is an analogue of human C1INH and is obtained from the milk of rabbits expressing the gene encoding for human C1INH. 
Konestat alfa, rekombinantna humana sestavina komplementa 1 (C1) zaviralca esteraze (rhC1INH), je analog humanega C1INH in se ga pridobiva iz mleka kuncev, ki izražajo kodiranje gena za humani
• 1 vial of 2100 U powder 
• 1 vialo z 2100 e. praška
Solvent vial: Water for injections 
Viala z vehiklom: voda za injekcije