natgillin/translations-raw huggingface dataset:
In patients at increased risk of further progression of renal impairment and in the elderly, renal function should be assessed more frequently, e.g. every 3-6 months. 
Bolnikom, pri katerih obstaja večje tveganje za nadaljnje napredovanje okvare ledvic, in pri starejših je treba delovanje ledvic oceniti pogosteje, npr. na 3 do 6 mesecev.
Frequencies of all uncommon adverse reactions were based on the individual mono-components data. 
Pogostnosti vseh občasnih neželenih učinkov temeljijo na podatkih o posameznih učinkovinah.
Long-term treatment with metformin has been associated with a decrease in vitamin B12 absorption which may very rarely result in clinically significant vitamin B12 deficiency. 
Dolgotrajno zdravljenje z metforminom je bilo povezano z zmanjšanjem absorpcije vitamina B12; to lahko zelo redko povzroči klinično pomembno pomanjkanje vitamina B12.
Qtrilmet is not recommended for children and adolescents under 18 years of age because it has not been studied in these patients. 
Uporaba zdravila Qtrilmet ni priporočljiva pri otrocih in mladostnikih, starih manj kot 18 let, ker pri teh bolnikih zdravilo ni raziskano.
Mean absolute lymphocyte counts remained stable with daily dosing up to 102 weeks in duration. 
Povprečno absolutno število limfocitov je ostalo stabilno med vsakodnevno uporabo do 102 tedna.
Qtrilmet should not be used during pregnancy. 
Zdravila Qtrilmet se med nosečnostjo ne sme uporabljati.
The European Medicines Agency has waived the obligation to submit the results of studies with Qtrilmet in all subsets of the paediatric population in the treatment of type 2 diabetes (see section 4.2 for information on paediatric use). 
Evropska agencija za zdravila je odstopila od zahteve za predložitev rezultatov študij z zdravilom Qtrilmet za vse podskupine pediatrične populacije za zdravljenje sladkorne bolezni tipa 2 (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
The majority of events were considered non-serious, mild or moderate in intensity, and resolved. 
Večina učinkov ni bila resnih, so bili blagi ali zmerni in so izzveneli.
Interaction studies have been performed with the individual active substances of Qtrilmet. 
Študije medsebojnih delovanj so izvedli s posameznimi učinkovinami zdravila Qtrilmet.
Because elderly patients (≥ 65 years) are more likely to have decreased renal function, this medicinal product should be used with caution as age increases. 
Ker je pri starejših bolnikih (≥ 65 let) verjetnost za zmanjšano delovanje ledvic večja, je treba to zdravilo z naraščajočo starostjo uporabljati previdno.
This medicine is for a type of diabetes called “type 2 diabetes”. 
To zdravilo je namenjeno za zdravljenje vrste sladkorne bolezni, imenovane “sladkorna bolezen tipa 2”.
When driving or using machines, it should be taken into account that dizziness has been reported in studies with saxagliptin. 
Pri vožnji ali upravljanju strojev je treba upoštevati, da je bila v študijah s saksagliptinom opisana omotica.
The AUC values of 5-OH-saxagliptin were also increased. 
Večja je bila tudi vrednost AUC 5-OH-saksagliptina.
Do not use this medicine after the expiry date, which is stated on the blister and carton after ‘EXP'. 
Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na pretisnem omotu in škatli poleg oznake ‘EXP'.
p-value < 0.0001. p-value = 0.0166. 
Vrednost p = 0,0166.
If no adequate strength of Qtrilmet is available, individual mono-components should be used instead of the modified-release combination. 
Če ni na voljo ustrezne jakosti zdravila Qtrilmet, je treba namesto kombinacije s prirejenim sproščanjem uporabiti posamezne sestavine ločeno.
Combinations requiring precautions for use 
Kombinacije, ki zahtevajo previdnost
The volume of distribution of saxagliptin was 205 L. 
Volumen porazdelitve saksagliptina je 205 l.
Treatment should be interrupted in patients who are hospitalised for major surgical procedures or acute serious medical illnesses. 
Zdravljenje je treba prekiniti pri bolnikih, sprejetih v bolnišnico za večje operacije ali zaradi akutnih resnih internističnih bolezni.
The three medicines in Qtrilmet lower the amount of sugar in the blood by causing it to be taken up into cells or passed out of the body in the urine. 
Tri zdravila v zdravilu Qtrilmet zmanjšajo količino sladkorja v krvi; to dosežejo tako, da ali povzročijo njegovo vstopanje v celice ali njegovo izločanje iz telesa z urinom.
The increases in creatinine were generally transient during continuous treatment or reversible after discontinuation of treatment. 
Zvišanja kreatinina so bila med nadaljevanjem zdravljenjem na splošno prehodna oziroma po prenehanju zdravljenja reverzibilna.
Due to the limited therapeutic experience with this medicinal product in patients 75 years and older, initiation of therapy is not recommended in this population. 
Zaradi omejenih terapevtskih izkušenj s tem zdravilom pri bolnikih, starih 75 let ali več, uvedba zdravljenja pri tej skupini bolnikov ni priporočljiva.
Patients with signs and symptoms of urinary tract infections should be evaluated and promptly treated, if indicated. 
Bolnike z znaki in simptomi okužbe sečil je treba ovrednotiti in jih nemudoma zdraviti, če je indicirano.
Patients and/or care-givers should be informed on the risk of lactic acidosis. 
Bolnike in/ali njihove skrbnike je treba opozoriti na tveganje laktacidoze.
Organic cation transporters (OCT) Metformin is a substrate of both transporters OCT1 and OCT2. 
Prenašalci organskih kationov (OCT - Organic cation transporters) Metformin je substrat prenašalcev OCT1 in OCT2.
Do not stop taking Qtrilmet without talking to your doctor first. 
Ne prenehajte jemati zdravila Qtrilmet, ne da bi se prej posvetovali z zdravnikom.
Metformin: The available data in subjects with moderate renal insufficiency are scarce and no reliable estimation of the systemic exposure to metformin in this subgroup as compared to subjects with normal renal function could be made. 
Metformin: Podatkov pri osebah z zmerno insuficienco ledvic je malo in tako ni bilo mogoče zanesljivo oceniti sistemske izpostavljenosti metforminu v tej podskupini v primerjavi z osebami z normalnim delovanjem ledvic.
When the patient plans to become pregnant, and during pregnancy, it is recommended that diabetes is not treated with this medicinal product, but insulin be used to maintain blood glucose levels as close to normal as possible, to reduce the risk of malformations of the foetus associated with abnormal blood glucose levels. 
Ko bolnica načrtuje nosečnost in med nosečnostjo, je priporočljivo, da se za zdravljenje sladkorne bolezni ne uporablja tega zdravila, temveč insulin, da bi vzdrževali koncentracijo glukoze v krvi čim bližje normalni in tako zmanjšali tveganje za malformacije ploda, povezane z nenormalno koncentracijo glukoze v krvi.
To control your diabetes, you need to follow your doctor's advice on diet and exercise, even when you are taking this medicine. 
Za obvladovanje sladkorne bolezni morate upoštevati zdravnikova navodila glede diete in telesne dejavnosti, tudi če jemljete to zdravilo.
Your doctor may prescribe a medicine to treat your allergic reaction and change your diabetes medicine. 
Zdravnik vam bo morda predpisal zdravilo za zdravljenje alergijske reakcije in zamenjal zdravilo za sladkorno bolezen.
HbA1c change from baseline at week 24 excluding data after rescue for randomised subjects - studies MB102129 and CV181168 
Sprememba HbA1c od izhodišča do 24. tedna, izključujoč podatke pri randomiziranih preiskovancih, pri katerih so uporabili rešilne ukrepe - študiji MB102129 in CV181168
n = number of subjects with non-missing baseline and a week 24 value. 
n = število preiskovancev, pri katerih ni bilo manjkajočih vrednosti, ne izhodiščne, ne po 24 tednih.
Use of alternative methods to monitor glycaemic control is advised. 
Priporoča se uporaba drugih metod za nadziranje urejenosti glikemije.
Qtrilmet has no or negligible influence on the ability to drive and use machines. 
Zdravilo Qtrilmet nima vpliva ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja strojev.
Onset of symptoms following initiation of therapy may be rapid or may occur after longer periods of treatment. 
Simptomi se lahko pojavijo kmalu po začetku zdravljenja ali po daljšem obdobju zdravljenja.
oedema peripheral 
periferni edemi
Lactic acidosis Vitamin B12 deficiency 
laktacidoza pomanjkan je vitamina B12
Additional safety data include clinical trials, post-authorisation safety studies and post-marketing experience with the mono-components. 
Dodatni podatki o varnosti izvirajo iz kliničnih preskušanj, študij varnosti po odobritvi dovoljenja za promet z zdravilom in izkušenj s posameznimi sestavinami v obdobju trženja.
Therapeutic experience in patients 65 years and older is limited, and very limited in patients 75 years and older. 
Terapevtskih izkušenj pri bolnikih, starih 65 let ali več, je malo, pri bolnikih, starih 75 let ali več, pa zelo malo.
* LRM = Longitudinal repeated measures using values prior to rescue. 
* LPM = longitudinalne ponovljene meritve z uporabo vrednosti pred reševalnim ukrepanjem.
Common A Uncommon B Rare Very rare Not known 
Zelo redki Neznana pogostnost
Patients should be advised of the characteristic symptoms of heart failure, and to immediately report such symptoms. 
Bolnike je treba seznaniti z značilnimi simptomi srčnega popuščanja in jim naročiti, da morajo o takšnih simptomih takoj poročati.
The safety and efficacy in patients with type 1 diabetes have not been established and Qtrilmet should not be used in patients with type 1 diabetes. 
Varnost in učinkovitost pri bolnikih s sladkorno boleznijo tipa 1 nista ugotovljeni in zdravila Qtrilmet se ne sme uporabljati za zdravljenje takšnih bolnikov.
This may occur regardless of blood glucose level. 
To se lahko pojavi ne glede na koncentracijo glukoze v krvi.
These may be symptoms of another rare, but very serious, sometimes life-threatening condition called diabetic ketoacidosis. 
To so lahko simptomi druge redke, toda zelo resne in včasih smrtno nevarne motnje, imenovane diabetična ketoacidoza.
It is important to check your feet regularly - and follow the advice on foot care from your health care professional. 
Pomembno je redno pregledovanje stopal in upoštevanje vseh nasvetov za oskrbo stopal, ki ste jih dobili od zdravstvenega delavca.
This decrease in mean absolute lymphocyte count was not associated with clinically relevant adverse reactions. 
To zmanjšanje povprečnega absolutnega števila limfocitov ni bilo povezano s klinično pomembnimi neželenimi učinki.
Due to its mechanism of action, patients taking dapagliflozin will test positive for glucose in their urine. 
Zaradi mehanizma delovanja zdravila imajo bolniki, ki jemljejo dapagliflozin, pozitiven izvid testa za glukozo v urinu.
Qtrilmet must be discontinued at the time of surgery with general, spinal or epidural anaesthesia. 
Uporabo zdravila Qtrilmet je treba prekiniti v času kirurškega posega v splošni, spinalni ali epiduralni anesteziji.
In particular, talk to your doctor before taking Qtrilmet if you are taking any of the following medicines: 
Še zlasti se pred uporabo zdravila Qtrilmet posvetujte z zdravnikom, če jemljete katero od naslednjih zdravil:
If you have type 2 diabetes, your pancreas does not make enough insulin or your body is not able to use the insulin it produces properly. 
Če imate sladkorno bolezen tipa 2, v trebušni slinavki ali ne nastaja dovolj insulina ali pa telo ne zmore uporabiti insulina, ki ustrezno nastaja v trebušni slinavki.
Avoid excessive alcohol intake while taking Qtrilmet since this may increase the risk of lactic acidosis (see “Warnings and precautions” and “Do not take Qtrilmet if you”). 
Med jemanjem zdravila Qtrilmet se izogibajte prekomernemu uživanju alkohola, kajti to lahko poveča tveganje za laktacidozo (glejte “Opozorila in previdnostni ukrepi” in “Ne jemljite zdravila Qtrilmet”).
Metformin: Plasma protein binding is negligible. 
Metformin: Vezava na beljakovine v plazmi je zanemarljiva.
It is taken on its own, or it can be combined with a different type of diabetes medicine called a sulphonylurea. 
Uporablja se samo, mogoče pa ga je uporabljati tudi v kombinaciji z drugačno vrsto zdravil za sladkorno bolezen, imenovano sulfonilsečnine.
There was no effect of food on Cmax and Tmax of metformin. 
Hrana ni vplivala na Cmax in tmax metformina.
Your doctor may ask you to stop taking Qtrilmet. 
Zdravnik vam lahko naroči, da nehate jemati zdravilo Qtrilmet.
Therefore, dapagliflozin is not expected to alter the metabolic clearance of co-administered medicinal products that are metabolised by these enzymes. 
Zato ni pričakovati, da bi dapagliflozin spremenil presnovni očistek sočasno uporabljenih zdravil, ki jih presnavljajo ti encimi.
Qtrilmet is only given to adults aged 18 years and older. 
Zdravilo Qtrilmet se uporablja le pri odraslih, starih 18 let ali več.
The absolute oral bioavailability of dapagliflozin following the administration of a 10 mg dose is 78%. 
Absolutna peroralna biološka uporabnost dapagliflozina po uporabi 10-mg odmerka je 78 %.
The clinical relevance of the skin lesions is not known, and skin lesions have not been observed in humans. 
Klinični pomen kožnih sprememb ni znan in pri človeku kožnih sprememb niso opazili.
Before initiating Qtrilmet, factors in the patient history that may predispose to ketoacidosis should be considered. 
Pred uvedbo zdravila Qtrilmet je treba v bolnikovi anamnezi oceniti dejavnike, ki bi lahko povečali nagnjenost h ketoacidozi.
Dapagliflozin: Dapagliflozin is approximately 91% protein bound. 
Dapagliflozin: Dapagliflozin je približno 91-odstotno vezan na beljakovine.
Metformin No clinically relevant interaction has been identified. 
Metformin Klinično pomembnega medsebojnega delovanja niso ugotovili.
If this happens you must stop taking Qtrilmet and contact a doctor or the nearest hospital immediately, as lactic acidosis may lead to coma. 
Če se to zgodi, morate prenehati jemati zdravilo Qtrilmet in se nemudoma posvetovati z zdravnikom ali iti v najbližjo bolnišnico, kajti laktacidoza lahko vodi v komo.
The patient should be informed and more frequent blood glucose monitoring performed, especially at the beginning of treatment with such medicinal products, and observed for loss of blood glucose control or hypoglycaemia. 
Bolnika je treba s tem seznaniti in potrebno je pogosto spremljanje glukoze v krvi, zlasti na začetku zdravljenja s takšnimi zdravili; bolnika je treba spremljati glede izgube nadzora nad glukozo v krvi ali hipoglikemije.
Each tablet is to be swallowed whole. 
Bolnik mora vsako tableto pogoltniti celo.
The treatment groups were proportionally well balanced with regard to demographics, subject characteristics, disease characteristics, and medical history. 
Terapevtske skupine so bile v razmerjih dobro uravnotežene, kar zadeva demografske značilnosti, značilnosti preiskovancev, značilnosti bolezni in zdravstveno anamnezo.
Thereafter, glimepiride/placebo dose were kept constant, except for down-titration to prevent hypoglycaemia. 
Potem je ostal odmerek glimepirida/placeba stalen, razen v primeru zmanjšanja za preprečitev hipoglikemij.
What you need to know before you take Qtrilmet 
Kaj morate vedeti, preden boste vzeli zdravilo Qtrilmet
Do not take Qtrilmet if any of the above apply to you. 
Ne vzemite zdravila Qtrilmet, če kaj od naštetega velja za vas.
The corresponding plasma Cmax values were 24 ng/mL and 47 ng/mL, respectively. 
Ustrezni vrednosti Cmax v plazmi sta bili 24 ng/ml in 47 ng/ml.
When starting or using such products in combination with metformin, close monitoring of renal function is necessary. 
Na začetku uporabe in med uporabo takšnih zdravil v kombinaciji z metforminom je treba skrbno spremljati delovanje ledvic.
The effect in HbA1c observed at week 24 was sustained at week 52. 
Učinek na HbA1c, opažen 24. teden, se je ohranil do 52. tedna.
Each tablet contains 48 mg of lactose (as anhydrous). 
Ena tableta vsebuje 48 mg laktoze (v obliki brezvodne laktoze).
The same recommendations for monitoring of renal function apply to elderly patients as to all patients (see sections 4.2, 4.4, 4.8 and 5.1). 
Glede spremljanja delovanja ledvic veljajo za starejše bolnike enaka priporočila kot za vse bolnike (glejte poglavja 4.2, 4.4, 4.8 in 5.1).
Saxagliptin: Across clinical studies in the saxagliptin programme a small decrease in absolute lymphocyte count was observed, approximately 100 cells/microL relative to placebo. 
Saksagliptin: V programu kliničnih študij saksagliptina so opažali majhno zmanjšanje absolutnega števila limfocitov, približno 100 celic/mikroliter v primerjavi s placebom.
Diabetic skin and foot problems 
Diabetične kožne spremembe in težave s stopali
Diagnostic laboratory findings are decreased blood pH (< 7.35), increased plasma lactate levels above 5 mmol/L, and an increased anion gap and lactate/pyruvate ratio. 
Diagnostični laboratorijski izvidi so zmanjšan pH krvi (< 7,35), zvišane ravni laktata v plazmi nad 5 mmol/l ter povečana anionska vrzel in razmerje laktat/piruvat.
Considering the short latency between first drug exposure and tumour diagnosis, a causal relationship to any specific tumour type is considered unlikely. 
Glede na kratko latenco med prvo izpostavljenostjo zdravilu in diagnozo tumorja vzročna povezava z nobeno od specifičnih vrst tumorjev ni verjetna.
No dose adjustment is recommended. 
Ni priporočil za prilagoditev odmerka.
Monitoring glycaemic control with 1,5-AG assay is not recommended as measurements of 1,5-AG are unreliable in assessing glycaemic control in patients taking SGLT2 inhibitors. 
Spremljanje urejenosti glikemije s testom z 1,5-AG ni priporočljivo, ker so meritve 1,5-AG nezanesljive za ocenjevanje urejenosti glikemije pri bolnikih, ki prejemajo zaviralce SGLT2.
In case of dehydration (severe diarrhoea or vomiting, fever or reduced fluid intake), Qtrilmet should be temporarily discontinued and contact with a health care professional is recommended. 
V primeru dehidracije (huda driska ali bruhanje, zvišana telesna temperatura ali zmanjšan vnos tekočine) je treba uporabo zdravila Qtrilmet začasno prekiniti in priporočljivo je, da se bolnik posvetuje z zdravstvenim delavcem.
Metformin: Renal clearance of metformin is > 400 mL/min, indicating that metformin is eliminated by glomerular filtration and tubular secretion. 
Metformin: Ledvični očistek metformina je > 400 ml/min, kar kaže, da se zdravilo izloča z glomerularno filtracijo in tubularno sekrecijo.
The average renal clearance of saxagliptin (~230 mL/min) was greater than the average estimated glomerular filtration rate (~120 mL/min), suggesting some active renal excretion. 
Povprečni ledvični očistek saksagliptina (~230 ml/min) je bil večji od povprečne ocenjene hitrosti glomerularne filtracije (~120 ml/min); to kaže na določen delež aktivnega ledvičnega izločanja.
The extent of metformin absorption (as measured by AUC) from the metformin extended-release tablet increased by approximately 50% when given with food. 
Med uporabo s hrano se je obseg absorpcije metformina (merjen z vrednostjo AUC) iz tablet metformina s podaljšanim sproščanjem povečal za približno 50 %.
If it is less than 12 hours since you should have taken your daily dose, take a dose of Qtrilmet as soon as you remember. 
- Če je od tedaj, ko bi morali vzeti svoj dnevni odmerek, minilo manj kot 12 ur, vzemite odmerek zdravila Qtrilmet, čim se spomnite.
Of the 1,169 subjects treated in the pooled safety data from the 3 clinical trials, 1,007 subjects (86.1%) were aged < 65 years, 162 subjects (13.9%) were aged ≥ 65 years and 9 subjects (0.8%) were aged ≥ 75 years. 
Od 1169 preiskovancev, zajetih v združene podatke o varnosti iz 3 kliničnih preskušanj, je bilo 1007 preiskovancev (86,1 %) starih < 65 let, 162 preiskovancev (13,9 %) ≥ 65 let in 9 preiskovancev (0,8 %) ≥ 75 let.
Other medicines and Qtrilmet 
Druga zdravila in zdravilo Qtrilmet
Gastrointestinal symptoms (subsumed terms included nausea, vomiting, diarrhoea, abdominal pain, and loss of appetite) occur most frequently during initiation of therapy and resolve spontaneously in most cases. 
Gastrointestinalni simptomi (kar vključuje izraze navzea, bruhanje, driska, bolečine v trebuhu in izguba apetita) se najpogosteje pojavijo med uvedbo zdravljenja in večinoma spontano izzvenijo.
A clinically relevant effect with other inducers (e.g. carbamazepine, phenytoin and phenobarbital) is not expected. 
Klinično pomembnega učinka med uporabo z drugimi induktorji (npr. karbamazepinom, fenitoinom ali fenobarbitalom) ni pričakovati.
Administration with a high-fat meal decreases dapagliflozin Cmax by up to 50% and prolonged Tmax by approximately 1 hour, but does not alter AUC as compared with the fasted state. 
Uporaba z zelo mastnim obrokom zmanjša Cmax dapagliflozina do 50 % in podaljša njegov tmax za približno 1 uro, ne spremeni pa njegove vrednosti AUC v primerjavi s stanjem na tešče.
Similarly, in controlled clinical studies in patients with type 2 diabetes, the antihyperglycaemic effect of metformin was comparable in males and females. 
Podobno je bil v kontroliranih kliničnih študijah pri bolnikih s sladkorno boleznijo tipa 2 antihiperglikemični učinek metformina pri moških in ženskah primerljiv.
Interference with 1,5-anhydroglucitol (1,5-AG) assay 
Vpliv na test z 1,5-anhidroglucitolom (1,5-AG)
Lactic acidosis, seen very rarely (may affect up to 1 in 10,000 people) Qtrilmet may cause a very rare, but very serious side effect called lactic acidosis. 
- Laktacidoza, ki je zelo redka (pojavi se lahko pri največ 1 od 10.000 bolnikov) Zdravilo Qtrilmet lahko povzroči zelo redek, toda zelo resen neželen učinek, imenovan laktacidoza.
Each belongs to a group of medicines called “oral anti-diabetics”. 
Vsa spadajo v skupino zdravil, ki jih imenujemo peroralni antidiabetiki.
If renal function falls below GFR < 60 mL/min, treatment should be discontinued. 
Če se delovanje ledvic zmanjša pod GFR < 60 ml/min, je treba to zdravilo prenehati uporabljati.
If you need major surgery, you must stop taking Qtrilmet during and for some time after the operation. 
Če potrebujete večji kirurški poseg, morate prenehati jemati zdravilo Qtrilmet v času posega in nekaj časa po njem.
High overdose may lead to lactic acidosis (see sections 2 and 4). 
Visok prekomeren odmerek lahko povzroči laktacidozo (glejte poglavji 2 in 4).
Modified-release tablet (tablet). 
tableta s prirejenim sproščanjem (tableta)
Low blood sugar levels (hypoglycaemia), seen very commonly (may affect more than 1 in 10 people) if used with other diabetes medicines which cause hypoglycaemia. 
- Nizek krvni sladkor (hipoglikemija), pojavi se zelo pogosto (pojavi se lahko pri več kot 1 od 10 bolnikov), če je to zdravilo uporabljeno skupaj z drugimi zdravili za sladkorno bolezen, ki povzročajo hipoglikemijo.
In addition, patients should be alerted to the risk of hypoglycaemia when this medicinal product is used in combination with other glucose-lowering medicinal products known to cause hypoglycaemia (e.g. insulin and sulphonylureas). 
Poleg tega je treba bolnike opozoriti na tveganje za hipoglikemijo, če je to zdravilo uporabljeno v kombinaciji z drugimi antidiabetičnimi zdravili, za katere je znano, da povzročajo hipoglikemijo (npr. insulin, sulfonilsečnine).
The mean age was 53.8 years and 49.8% of patients were female. 
Povprečna starost je bila 53,8 leta in 49,8 % je bilo žensk.
In the clinical program, 34.4% of subjects had a history of cardiovascular disease (excluding hypertension) at baseline and 67.9% had hypertension. 
V kliničnem programu je imelo izhodiščno anamnezo srčno-žilne bolezni (izključujoč hipertenzijo) 34,4 % preiskovancev; hipertenzijo jih je imelo 67,9 %.
Following a single 50 mg dose of 
Po enkratnem 50-mg odmerku
Metformin: Following a single oral dose of metformin extended-release tablet, Cmax is achieved with a median value of 7 hours and a range of 4 to 8 hours. 
Metformin: Po enkratnem peroralnem odmerku metformina v tabletah s podaljšanim sproščanjem je bila Cmax dosežena po mediano 7 urah in v razponu od 4 do 8 ur.