natgillin/translations-raw huggingface dataset:
The active substance in Levetiracetam Actavis, levetiracetam, is an anti-epileptic medicine. 
Zdravilna učinkovina zdravila Levetiracetam Actavis, levetiracetam, je zdravilo proti epilepsiji.
Why has Levetiracetam Actavis been approved? 
Zakaj je bilo zdravilo Levetiracetam Actavis odobreno?
When Levetiracetam Actavis is used on its own, the starting dose is 250 mg twice a day, increasing two weeks later to 500 mg twice a day. 
Začetni samostojni odmerek zdravila Levetiracetam Actavis je 250 mg dvakrat dnevno, po dveh tednih jemanja pa se poveča na 500 mg dvakrat dnevno.
How has Levetiracetam Actavis been studied? 
Kako je bilo zdravilo Levetiracetam Actavis raziskano?
What is Levetiracetam Actavis used for? 
Za kaj se zdravilo Levetiracetam Actavis uporablja?
How is Levetiracetam Actavis used? 
Kako se zdravilo Levetiracetam Actavis uporablja?
When Levetiracetam Actavis is added to another anti-epileptic treatment, the starting dose in patients over 12 years weighing more than 50 kg is 500 mg twice a day. 
Odmerki se lahko glede na bolnikov odziv še naprej povečujejo v dvotedenskih razmakih do največjega odmerka 1 500 mg dvakrat dnevno.Kadar se zdravilo Levetiracetam Actavis dodaja drugemu zdravilu proti epilepsiji, je začetni odmerek pri bolnikih, starejših od 12 let, ki tehtajo več kot 50 kg, 500 mg dvakrat dnevno.
What is Levetiracetam Actavis? 
Kaj je zdravilo Levetiracetam Actavis?
How does Levetiracetam Actavis work? 
Kako zdravilo Levetiracetam Actavis deluje?
You will also need 2 syringes: 
Prav tako boste potrebovali 2 brizgi:
Date of first authorisation: 30 July 2018 
Datum prve odobritve: 30. julij 2018
There might be local regulations for this. 
Morda obstajajo lokalni predpisi.
• you are pregnant 
• če ste noseči;
Throw it away and start again from step 1. 
Zavrzite jo in začnite znova s 1. korakom.
Annual reports to be submitted as part of the annual re-assessment. 
Letna poročila je treba predložiti kot del ponovne letne ocene.
• ‘U' means ‘Units'. 
• "U" pomeni "enote" (Units).
A minimum clinical response is defined as at least: 
Najmanjši klinični odziv je opredeljen kot vsaj:
EXP After reconstitution: use immediately. 
EXP Po rekonstituciji: porabiti takoj.
3) Wash your hands before preparing the medicine. 
3) Pred pripravo zdravila si umijte roke.
Frequency not known* 
Pogostost ni znana*
Generalised LD 
Generalizirana LD
• loss of interest in food 
• izguba zanimanja za hrano
Dose increases should not be made more frequently than every 4 weeks. 
Odmerka ni priporočljivo povečevati pogosteje kot vsake 4 tedne.
This improves the ability of the body to control energy levels. 
To izboljša sposobnost vašega telesa pri nadziranju ravni energije.
Details on how to access these are available from your doctor. 
Podrobnosti o dostopu do teh informacij so na voljo pri vašem zdravniku.
This can help make the injections more comfortable. 
Tako je lahko injiciranje bolj udobno.
Overall, the safety and tolerability of metreleptin are similar in children and adults. 
Na splošno sta varnost in toleranca za metreleptin pri otrocih in odraslih podobni.
Step G: Throwing away used materials 
Korak G: Odstranjevanje rabljenih materialov
• Then have your normal dose the next day. 
• Nato naslednji dan vzemite svoj običajni odmerek.
The educational programme is aimed at increasing awareness among healthcare professionals and patients/carers about the important risks contained in the Risk Management Plan. 
Izobraževalni program je namenjen povečanju ozaveščenosti zdravstvenih delavcev in bolnikov/skrbnikov o pomembnih tveganjih, vsebovanih v načrtu za obvladovanje tveganj.
The final study report should be submitted by 2022. 
Končno poročilo o študiji je treba predložiti do leta 2022.
The co-primary efficacy endpoints in this study were defined as: 
Glavni opazovani parametri učinkovitosti v tej študiji so bili opredeljeni, kot sledi:
SD = standard deviation 
P SD = standardna deviacija
On a clean, well-lit work surface, place the following items: 
Na čisto, dobro osvetljeno površino položite naslednje predmete:
If this happens, do not drive or use any tools or machines. 
V tem primeru ne upravljajte vozil ali uporabljajte kakršnega koli orodja ali strojev.
• unusually heavy or long menstrual bleeding 
• neobičajno močna ali dolga menstrualna krvavitev
• 15% reduction in triglycerides (TGs) 
• 15-odstotno zmanjšanje trigliceridov (TG)
You might also see smaller air bubbles in the syringe. 
Prav tako lahko v brizgi vidite manjše zračne mehurčke.
1) Get together all the materials you will need for your injection. 
1) Pripravite ves material, ki ga boste potrebovali za injiciranje.
An example is given below for the different syringe sizes. 
Spodaj je primer za različne velikosti brizg.
Your doctor might need to change your treatment. 
Zdravnik vam bo morda moral zamenjati zdravljenje.
The final study report should be submitted by 2024. 
Končno poročilo o študiji je treba predložiti do leta 2024.
If you cannot contact your doctor, you should seek emergency medical help: 
Če ne morete stopiti v stik s svojim zdravnikom, poiščite ambulanto za nujno zdravniško pomoč:
All three patients had acquired generalised LD. 
Vsi trije bolniki so imeli generalizirano LD.
In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products, except those mentioned in section 6.6. 
Zaradi pomanjkanja študij kompatibilnosti zdravila ne smemo mešati z drugimi zdravili, razen s tistimi, ki so omenjena v poglavju 6.6.
• 0.5% HbA1c reduction and/or 25% reduction in insulin requirements and / or 
• 0,5-odstotno zmanjšanje HbA1c in/ali 25-odstotno zmanjšanje potrebe po insulinu in/ali
Step A: Setting up 
Korak A: Nastavitev
• It is important to gradually reduce the dose over two weeks because this can help prevent a sudden increase in the levels of fat (called ‘triglycerides') in your blood. 
• Pomembno je, da odmerek zmanjšujete postopoma v obdobju dveh tednov, saj tako pomagate preprečiti nenadno povišanje ravni maščob (imenovanih "trigliceridi") v vaši krvi.
• helping the insulin in your body manage sugar levels. 
• insulinu v vašem telesu pomaga uravnavati ravni sladkorja.
• If you forget to inject a dose, inject it as soon as you remember. 
• Če pozabite injicirati odmerek, ga injicirajte takoj, ko se spomnite.
You can inject this medicine into the following areas: 
Zdravilo lahko injicirate v naslednja mesta:
It is anticipated that most children will require increasing per kg dose, especially as they reach puberty. 
Predvideva se, da bo treba pri večini otrok odmerek na kg povečati, predvsem ob dosegu pubertete.
Your doctor will have prescribed the correct dose for you, based on the following: 
Zdravnik vam bo predpisal primeren odmerek za vas na osnovi naslednjih dejstev:
If you are using a medicine such as insulin or other medicines to treat diabetes, your doctor will closely monitor your blood sugar. 
Če uporabljate zdravila, kot so insulin ali druga zdravila za zdravljenje sladkorne bolezni, bo zdravnik pozorno spremljal vaš krvni sladkor.
• Your doctor will decide if you should use Myalepta and will monitor you during treatment. 
• Zdravnik se bo odločil, ali boste uporabljali zdravilo Myalepta in vas med zdravljenjem nadziral.
This is because it is not known how this medicine will affect children under these ages. 
Vzrok je ta, da ni znano, kakšne učinke bo zdravilo imelo pri otrocih teh starosti.
Frequencies are defined as very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1,000 to < 1/100); rare (≥ 1/10,000 to < 1/1,000); very rare (< 1/10,000); not known (cannot be estimated from available data). 
Pogostosti so opredeljene kot zelo pogosti (≤ 1/10); pogosti (≤ 1/100 do < 1/10); občasni (≤ 1/1.000 do < 1/100); redki (≤ 1/10.000 do < 1/1.000); zelo redki (< 1/10.000); neznana pogostnost (ni mogoče oceniti iz razpoložljivih podatkov).
No effects on the distribution of subcutaneous fat are expected. 
Učinkov na distribucijo podkožnega maščevja ni pričakovati.
- Detailed instructions for use. 
- Podrobna navodila za uporabo.
It is also aimed to guide prescribers about the appropriate management of these risks. 
Njegov cilj je tudi dati napotke zdravnikom, ki predpisujejo zdravilo o ustreznem obvladovanju teh tveganj.
This leaflet was last revised in (month YYYY). 
Navodilo je bilo nazadnje revidirano dne (mesec LLLL).
Draft protocol to be submitted 3 months after notification of the European Commission decision. 
Osnutek protokola je treba predložiti 3 mesece po objavi sklepa Evropske komisije.
Do not shake or vigorously mix. 
Ne stresajte ali močno mešajte.
• The syringe you need to use to inject this medicine depends on the dose prescribed for you. 
• Brizga, ki jo morate uporabiti za injiciranje tega zdravila, je odvisna od predpisanega odmerka.
In particular, tell your doctor if you are taking any of the following medicines: 
Zdravniku še posebej povejte, ali jemljete katero od naslednjih zdravil:
Data from clinical trials do not support safety and efficacy in patients with HIV-related LD. 
Podatki iz kliničnih študij ne podpirajo varnosti in učinkovitosti pri bolnikih z LD v povezavi z virusom HIV.
Therefore, an additional non-hormonal contraceptive method should be considered during treatment. 
Zato je treba med zdravljenjem razmisliti o dodatni, nehormonski metodi kontracepcije.
Serious and severe infections 
Resne in hude okužbe
Additional training information 
Dodatne informacije za usposabljanje
• an increase in ‘HbA1c' in your blood, shown in tests 
• povišana raven "HbA1c" v krvi, ki se pokaže pri preiskavah
Possible side effects with this medicine: 
Možni neželeni učinki pri tem zdravilu:
Do not use this medicine after the expiry date which is stated on the vial and carton. 
Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na viali in škatli.
While using this medicine, you or your child will be monitored by your doctor, who will decide the dose you or your child should use. 
Med uporabo tega zdravila bo vas ali vašega otroka spremljal zdravnik, ki bo določil odmerek za vas ali vašega otroka.
The patient will receive a carton containing 1 or 30 vials of Myalepta, depending on the pack size, which should be stored in a refrigerator until the day of use. 
Bolnik prejme škatlo z 1 ali 30 vialami zdravila Myalepta, odvisno od velikosti pakiranja, ki jo mora do dneva uporabe hraniti v hladilniku.
Do not inject into a muscle. 
Ne injicirajte v mišico.
22) Carefully choose where you want to inject Myalepta. 
22) Previdno izberite mesto, kjer želite injicirati zdravilo Myalepta.
Signs of an allergic reaction can be seen in section 4 under “Allergic reactions”. 
Znaki alergijske reakcije so našteti v 4. poglavju pod "Alergijske reakcije".
Always use a new syringe. 
Vedno uporabite novo brizgo.
Take your time to carefully prepare and inject your medicine, which when including the period of the vial warming up after being taken out of the fridge, can be approximately 20 minutes in total. 
Vzemite si čas in previdno pripravite in si injicirajte svoje zdravilo, kar lahko, vključno z obdobjem segrevanja viale po tem, ko jo vzamete iz hladilnika, traja približno 20 minut.
• Do not use the syringes more than once. 
• Brizg ne uporabite več kot enkrat.
Discontinuation in patients at risk for pancreatitis 
Prekinitev pri bolnikih s tveganjem za pankreatitis
• you are allergic to metreleptin or any of the other ingredients of this medicine (listed in section 6). 
• če ste alergični na metreleptin ali katero koli sestavino tega zdravila (navedeno v poglavju 6).
Your doctor will decide if you should stop using this medicine. 
Zdravnik se bo odločil, ali morate prenehati z jemanjem tega zdravila.
Most of these patients (13 of 16) were able to stop insulin use within the first year of metreleptin. 
Večina teh bolnikov (13 od 16) je lahko prenehala uporabljati insulin v prvem letu jemanja metreleptina.
There are additional education training information and videos to help you understand how to use Myalepta correctly. 
Na voljo so dodatne informacije za usposabljanje in video posnetki, ki vam pomagajo razumeti, kako pravilno uporabljati zdravilo Myalepta.
25) With the other hand, hold the syringe like a pencil. 
25) Z drugo roko primite brizgo kot svinčnik.
• If you weigh 40 kg or less: 
• Če tehtate 40 kg ali manj:
In general, dose selection and modification for an elderly patient should be cautious, although no specific dose adjustment is recommended. 
Na splošno je treba biti pri izboru odmerka in prilagoditvi slednjega pri starejših bolnikih previden, čeprav posebna prilagoditev odmerka ni priporočena.
Influenza, Pneumonia 
Gripa, pljučnica
In one post-marketing case, an infant was exposed to a 10-fold overdose of metreleptin for 8 months. 
V enem primeru po prihodu zdravila na trg je bil dojenček 8 mesecev izpostavljen 10-kratnemu prevelikemu odmerku metreleptina.
• you have ever had problems with your blood (such as a low blood count) 
• če ste kadar koli imeli težave s svojo krvjo (kot je nizko število krvnih celic);
Also some other medicines can affect the way this medicine works. 
Prav tako lahko druga zdravila vplivajo na delovanje tega.
• very fast heartbeat 
• zelo hiter srčni utrip
The most frequently occurring adverse reactions from the clinical studies were hypoglycaemia (14%) and weight decreased (17%). 
Najpogostejša negativna učinka, ki sta se pojavila v kliničnih študijah, sta bila hipoglikemija (14 %) in izguba telesne teže (17 %).
• The glass ampoule should be at a 45 degree angle to the ground. 
• Steklena ampula mora biti pod kotom 45 stopinj glede na tla.
This being an approval under exceptional circumstances and pursuant to Article 14(8) of Regulation (EC) No 726/2004, the MAH shall conduct, within the stated timeframe, the following measures: 
DOVOLJENJA ZA PROMET Z ZDRAVILOM V IZJEMNIH OKOLIŠČINAH Ker gre za odobritev v izjemnih okoliščinah in ob upoštevanju člena 14(8) Uredbe (ES) št. 726/2004, mora imetnik dovoljenja za promet v določenem časovnem okviru izvesti naslednje ukrepe:
Gradually reducing your dose, and following a reduced fat diet may help to prevent this. 
Postopno zmanjšanje odmerka in upoštevanje diete z nizko vsebnostjo maščob pomaga to preprečiti.
Pack sizes of 1 or 30 vials. 
Velikosti pakiranja 1 ali 30 vial.
It is used in adults, adolescents and children 2 years or over: 
Uporablja se pri odraslih, mladostnikih in otrocih, starih 2 leti ali več:
• Women who could get pregnant should use effective contraception, including non-hormonal methods such as condoms, while using Myalepta. 
• Ženske, ki bi lahko zanosile, morajo med jemanjem zdravila Myalepta uporabljati učinkovito kontracepcijo, vključno z nehormonskimi metodami, kot so kondomi.
The medicinal product was administered subcutaneously either once daily or twice daily (in two equal doses). 
Zdravilo so dajali subkutano enkrat ali dvakrat dnevno (v dveh enakih odmerkih).
Hypoglycaemia, deemed as related to metreleptin treatment, occurred in 14.2% of patients studied. 
Hipoglikemija, ki se smatra kot povezana z zdravljenjem z metreleptinom, se je pojavila pri 14,2 % bolnikov v študiji.
Mean change among the 5 patients < 6 years of age was 0.2%. 
Povprečna sprememba pri 5 bolnikih < 6 let je bila 0,2 %.
• Do not try to prepare the medicine or inject yourself if you have not been trained. 
• Zdravila ne poskušajte pripraviti ali injicirati sami, če niste bili ustrezno poučeni, kako to narediti.
The effect of metreleptin on CYP450 enzymes may be clinically relevant for CYP450 substrates with narrow therapeutic index, where the dose is individually adjusted. 
Učinek metreleptina na encime CYP450 je lahko klinično relevanten za substrate CYP450 z ozkim terapevtskim indeksom, kjer se odmerek prilagaja individualno.
CONDITIONS OR RESTRICTIONS WITH REGARD TO THE SAFE AND EFFECTIVE USE OF THE MEDICINAL PRODUCT 
POGOJI ALI OMEJITVE Z ZVEZI Z VARNO IN UČINKOVITO UPORABO ZDRAVILA
• feeling very thirsty or hungry 
• močan občutek žeje ali lakote
You might feel dizzy or tired when using this medicine. 
Med uporabo tega zdravila ste lahko omotični ali se počutite utrujeno.
• Inject all of the medicine. 
• Injicirajte vso zdravilo.
28) Remove the syringe from the skin. 
28) Odmaknite brizgo od kože.
Use new syringes each time. 
Vsakič uporabite novo brizgo.
• Sometimes, large spaces of air (air pockets) get caught inside the syringe. 
• Včasih se v brizgo ujame velik prostor zraka (zračni žep).
• feeling more hungry than normal 
• večji občutek lakote kot običajno
This medicinal product contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially “sodium free”. 
To zdravilo vsebuje manj kot 1 mmol (23 mg) natrija na odmerek, kar v bistvu pomeni "brez natrija".
24) To inject under the skin, pinch the skin with one hand where you are going to inject. 
24) Da si zdravilo injicirate pod kožo, jo z eno roko nagubajte (uščipnite) na mestu, kjer želite injicirati.
Your doctor will also ask you to follow a reduced fat diet. 
Zdravnik vam bo prav tako predpisal dieto z nizko vsebnostjo maščob.
Actual amount of solution* 
Dejanski volumen raztopine*
What you need to know before you use Myalepta 3. 
Kaj morate vedeti, preden boste uporabili zdravilo Myalepta 3.
23) Clean the area where you will inject yourself with a clean alcohol swab and let the skin dry. 
23) Mesto injiciranja očistite s čistim alkoholnim robčkom in pustite, da se koža posuši.
Very common (may affect more than 1 in 10 people): • weight loss 
Zelo pogosti (lahko se pojavijo pri več kot 1 od 10 bolnikov): • izguba telesne mase
Prolonged gestation resulted in the death of some females during parturition and lower survival of offspring within the immediate postnatal period. 
Daljša gestacija je vodila do smrti nekaterih samic med porodom in manjše stopnje preživetja mladičev takoj po porodu.
Dose decreases based on weight loss may be made weekly. 
Zmanjšanje odmerka zaradi izgube telesne teže je možno enkrat tedensko.
Your doctor will change your dose of insulin or other medicines if needed. 
Po potrebi bo spremenil odmerek insulina ali drugih zdravil.
Never use remaining water for injection left over from a previous day's preparation of Myalepta solution. 
Nikoli ne uporabite vode za injekcije, ki je ostala od priprave raztopine zdravila Myalepta iz preteklega dne.
If you want to use the same area of the body for each injection, do not use the same spot that you used for your last injection. 
Če želite za vsako injekcije uporabiti isti del na telesu, pazite, da ne injicirate na isto točko kot prejšnjič.
• You must remove an air pocket and air bubbles from the syringe to make sure you get the correct amount of sterile water in the syringe. 
• Odstraniti morate zračni žep in zračne mehurčke iz brizge, da dobite pravilno količino sterilne vode v brizgo.
Leptin is a cytokine and has the potential to alter the formation of cytochrome P450 (CYP450) enzymes. 
Leptin je citokin in lahko spremeni tvorbo encimov citokroma P450 (CYP450).
o Your pharmacist will give you the correct syringe for injecting. 
o Farmacevt vam bo dal pravilno brizgo za injiciranje.
13) Hold the vial at 45 degree angle to the table and slowly push the plunger all the way down with your thumb. 
13) Vialo držite pod kotom 45 stopinj na mizo in bat s palcem počasi potisnite čisto navzdol.
Multiple dosing regimens were explored during the NIH study, which led to the posology recommended in section 4.2. 
Med študijo NIH je bilo preizkušenih več režimov odmerjanja, kar je vodilo do odmerjanja, priporočenega v poglavju 4.2.
Draft protocol to be submitted 6 months after notification of the European Commission decision 
Osnutek protokola je treba predložiti 6 mesecev po objavi sklepa Evropske komisije.
*Metreleptin is a recombinant human leptin analogue (produced in Escherichia coli cells by recombinant DNA technology to form recombinant methionyl-human leptin). 
*Metreleptin je rekombinantni analog humanega leptina (proizvaja se v celicah Escherichia coli z tehnologijo rekombinantne DNK, pri čemer se tvori rekombinantni humani-metionil leptin).
26) Gently insert the needle into the skin at approximately a 45 degree angle to the body. 
26) Nežno vstavite iglo v kožo pod kotom približno 45 stopinj na telo.
See steps 6-8 below on removal of air pockets and air bubbles from the syringe. 
Glejte korake 6 do 8 spodaj za odstranitev zračnih žepov in zračnih mehurčkov iz brizge.
Since it cannot be excluded that metreleptin may reduce exposure to substrates of CYP3A through enzyme induction, the efficacy of hormonal contraceptives may be reduced if co-administered with metreleptin. 
Ker ni mogoče izključiti, da lahko metreleptin zmanjša izpostavljenost substratom CYP3A z indukcijo encima, se lahko učinkovitost hormonskih kontraceptivov zmanjša, če se uporabljajo sočasno z metreleptinom.
Some medicines need to be monitored while you are using Myalepta since the dose of these medicines might need to be changed. 
Nekatera zdravila je treba med uporabo zdravila Myalepta spremljati, saj je morda treba odmerek teh zdravil spremeniti.
Visually inspect the vial containing the medicinal product. 
Vizualno preglejte vialo z zdravilom.
People with lipodystrophy can get a type of blood cancer called lymphoma, whether or not they are using Myalepta. 
Ljudje z lipodistrofijo lahko zbolijo za vrsto krvnega raka, ki se imenuje limfom, ne glede na to, ali uporabljajo zdravilo Myalepta ali ne.
• If you see an air pocket or any air bubbles, follow the same instructions described in step 7 to remove the air from the syringe. 
• Če vidite zračni žep ali zračne mehurčke, sledite istim navodilom, kot so opisana v 7. koraku,
Your doctor may decide that you inject yourself. 
Zdravnik se lahko odloči, da si boste zdravilo injicirali sami.
Reductions in HbA1c and TG may not be seen in children as metabolic abnormalities may not be present at the start of treatment. 
Zmanjšanja HbA1c in TG morda pri otrocih ne bodo opazna, saj presnovne nepravilnosti ob začetku zdravljenja morda še niso prisotne.
Injection site reactions were reported in 3.4% of patients with LD treated with metreleptin. 
Reakcije na mestu injiciranja so bile poročane pri 3,4 % bolnikov, pri katerih so LD zdravili z metreleptinom.
• medicines which suppress the immune system (such as cyclosporine) 
• zdravila, ki zavirajo imunski sistem (kot je ciklosporin);
8) Check the amount of water for injection 
8) Preverite količino vode za injekcije.
Important: Myalepta must be injected under the skin (‘subcutaneous'). 
Pomembno: Zdravilo Myalepta je treba injicirati pod kožo ("subkutano").
Your dose of Myalepta may change over time depending on how this medicine works for you. 
Vaš odmerek zdravila Myalepta se lahko s časom spremeni glede na to, kako to zdravilo pri vas deluje.
• or partial lipodystrophy has been caused by your body's response to something such as a viral illness (also called acquired lipodystrophy) 
• ali s parcialno lipodistrofijo, nastalo zaradi odziva lastnega telesa na nekaj, npr. na virusno obolenje (imenovana tudi pridobljena lipodistrofija).
Myalepta is available in packs containing 1 or 30 vials. 
Zdravilo Myalepta je na voljo v pakiranjih po 1 ali 30 vial.
• you have ever had inflammation of an organ called the pancreas (‘pancreatitis') 
• če ste kadar koli imeli vnetje organa, ki se imenuje trebušna slinavka ("pankreatitis").
• Do not use a double dose to make up for a forgotten dose. 
• Ne uporabite dvojnega odmerka, če ste pozabili uporabiti prejšnji odmerek.
Clinical trials of metreleptin did not include sufficient numbers of patients aged 65 and older to determine whether they respond differently from younger patients. 
Pri kliničnih študijah metreleptina ni sodelovalo dovolj bolnikov, starejših od 65 let, da bi bilo mogoče določiti, ali se na učinkovino odzivajo drugače od mlajših.
All patients had a history of pancreatitis and hypertriglyceridaemia. 
Vsi bolniki so imeli anamnezo pankreatitisa in hipertrigliceridemijo.
In order to avoid medication errors including overdose, dose calculation and dose adjustment guidelines below should be followed. 
V izogib napakam pri dajanju zdravila, vključno s prekomernim odmerjanjem, je treba upoštevati spodnji izračun za odmerek ter smernice za prilagajanje odmerka.