natgillin/translations-raw huggingface dataset:
• Partner of patient information card 
• podatke o zdravilu za bolnikovega partnerja.
• Product information 
• podatke o zdravilu;
o Need for close monitoring if liver enzymes measure > 3 × upper limit normal (ULN): > 3 and ≤ 5 × ULN: Confirm by another liver test; if confirmed, a decision should be made on an individual basis to continue or to stop Thelin administration. 
> 3 in ≤ 5 × ZMN: Potrdite z drugo preiskavo jeter; če je stanje potrjeno, se morate odločiti za nadaljevanje ali prekinitev zdravljenja z zdravilom Thelin za vsakega bolnika posebej.
• Patient information card 
• podatke o zdravilu za bolnika;
• That Thelin is hepatotoxic o Need for liver function tests prior to and during treatment o Contraindication in patients with pre-existing hepatic impairment (Child-Pugh Class AC). 
• da je zdravilo Thelin hepatotoksično o Potrebno je preverjati delovanje jeter pred in med zdravljenjem.
Partner of patient information card should include the following information: • That Thelin is teratogenic and that women of child bearing age must use effective contraception 
• da je zdravilo Thelin teratogeno in da morajo ženske v rodni dobi uporabljati učinkovito kontracepcijo.
• Effect of Thelin on bleeding o Interaction with warfarin and vitamin K antagonists leading to an increased INR o Need to decrease established dose of vitamin K antagonist upon starting sitaxentan therapy o Start vitamin K antagonists treatment at a reduced dose if already on sitaxentan sodium oNeed for regular monitoring of INR oBe aware of the potential for haemorrhage and investigate as appropriate o Increased risk of epistaxis and gingival bleeding 
o Pred začetkom zdravljenja s sitaksentanatom je potrebno zmanjšati uveljavljeni odmerek antagonistov vitamina K. o Če se bolnik že zdravi s natrijevim sitaksentanatom, je potrebno začeti zdravljenje z antagonisti vitamina K z zmanjšanim odmerkom.
• That Thelin is teratogenic o Use of effective contraception in women of child bearing age o Possible interaction with oral contraceptives and increased risk of thromboembolism o Need to advise female patients about teratogenicity, contraception, if necessary the need for pregnancy testing and what to do if they become pregnant o Referral of patients who become pregnant to a physician specialised or experienced in teratology and its diagnosis for evaluation and advice 
o Bolnice morajo biti poučene o teratogenosti ter se z zdravnikom posvetovati o kontracepciji, testu za ugotavljanje nosečnosti in kaj storiti, če zanosijo.
Tablet container (HDPE) 60 tablets 
plastenka (HDPE)
Blister (OPA/Alu/PVC) 60 tablets 
Številka EU Ime jakost farmacevtska oblika pot uporabe ovojnina velikost pakiranja pretisni omot (OPA/Alu/PVC)
This is especially important for infants and young children. 
To je posebej pomembno pri dojenčkih in mladih otrocih.
This list is not intended to be inclusive or comprehensive. 
Ta seznam ni vsevključujoč ali izčrpen.
Take the next dose as usual. 
Naslednji odmerek vzemite kot običajno.
They will tell you how to use the syringe correctly. 
Povedali vam bodo, kako pravilno uporabljati brizgo.
In some patients additional factor VIII was given. 
Nekateri bolniki so dobili dodaten faktor VIII.
In this picture we have pulled out the plunger so that you can see each part clearly. 
Na tej skici smo izvlekli bat, da lahko jasno vidite vsak del posebej.
Component of a multipack, can't be sold separately. 
Sestavni del multipakiranja, se ne prodaja ločeno.
{MM/YYYY} 
{MM/LLLL}
Date of first authorisation: 20 March 2001 Date of latest renewal: 20 March 2011 
Datum pridobitve dovoljenja za promet: 20. marec 2001 Datum podaljšanja dovoljenja za promet: 20. marec 2011
How do I measure the correct dose? 
Kako naj odmerim pravi odmerek
Do not transfer it to any other container. 
Ne prelivajte je v noben drug vsebnik.
Given twice daily with food 
Dvakrat na dan s hrano
Precautions to prevent transmission should be taken in accordance with national guidelines. 
Potrebni so previdnostni ukrepi za prenos v skladu z nacionalnimi smernicami.
Lopinavir can be used during pregnancy if clinically needed. 
Lopinavir se lahko uporablja med nosečnostjo, če je to klinično potrebno.
Individual SmPCs should be consulted. 
Upoštevati je potrebno posamezen SmPC.
Discuss with your doctor the precautions needed to avoid infecting other people. 
Posvetujte se s svojim zdravnikom o ukrepih, ki so potrebni, da se izognete okužbi drugih ljudi.
A causal relationship had been evoked, although the mechanism of action had not been elucidated. 
Pokazalo se je vzročno razmerje, a mehanizem delovanja ni razjasnjen.
This leaflet was last revised in: {MM/YYYY} 
Navodilo je bilo nazadnje revidirano: {MM/LLLL}
These changes may be seen on an ECG (electrocardiogram). 
Te spremembe je mogoče videti na EKG-ju (elektrokardiogramu).
Adults and adolescents 
Odrasli in mladostniki
Due to the possibility of undetected fructose intolerance, this medicinal product should only be given to babies and infants after consultation with a doctor. 
Zaradi možnosti neodkrite intolerance za fruktozo se sme to zdravilo dajati dojenčkom in otrokom samo po posvetu z zdravnikom.
See further the detailed description of the clinical studies. 
Glejte podroben opis kliničnih študij.
Other medicines may also contain alcohol and alcohol may be consumed in food and drinks. 
Druga zdravila lahko prav tako vsebujejo alkohol, možno pa ga je zaužiti tudi s hrano in pijačo.
On rare occasions these muscle disorders have been serious. 
redkih primerih so bile te mišične motnje resne.
Conclusions regarding the relevance of particular mutations or mutational patterns are subject to change with additional data, and it is recommended to always consult current interpretation systems for analysing resistance test results. 
Zaključki o pomembnosti določenih mutacij ali mutacijskih vzorcev se lahko spreminjajo z dodatnimi podatki, zato je priporočljivo, da se vedno upošteva trenutne sisteme interpretacije za analiziranje rezultatov preizkusa odpornosti.
Your doctor can explain these symptoms to you. 
Te simptome vam lahko razloži zdravnik.
The mean (SD) for the studies are reported in the table below. 
Povprečja (SD) za študije so opisana v preglednici spodaj.
If the condition persists or worsens, seek medical attention. 
Če stanje traja ali se poslabša, poiščite zdravniško pomoč.
The amount of alcohol in this medicine may affect your ability to drive or use machines and may affect your judgement and reaction times. 
Količina alkohola v tem zdravilu lahko vpliva na vašo sposobnost vožnje, upravljanja strojev ter vašo presojo in odzivne čase.
• increased appetite; 
- povečan apetit;
In more than half of the reported cases, treatment with protease inhibitors was continued or reintroduced if treatment had been discontinued. 
V več kot polovici primerov so zdravljenje z zaviralci proteaz nadaljevali ali znova uvedli, če je bilo zdravljenje prekinjeno.
Around 85% of patients had a viral load of < 100,000 copies/ml. 
Približno 85 % bolnikov je imelo virusno breme < 100.000 kopij/ml.
* Body surface area can be calculated with the following equation: 
* Telesno površino lahko izračunate po naslednji enačbi:
Animal studies have shown no effects on fertility. 
Študije na živalih niso pokazale vpliva na plodnost.
• If you cannot contact your doctor, go to the hospital. 
- Če ne morete kontaktirati svojega zdravnika, pojdite v bolnišnico.
• Continue to take this medicine until your doctor tells you otherwise. 
- To zdravilo jemljite, dokler vam zdravnik ne naroči drugače.
This is similar to an adult drinking 4-22 ml of beer or 1-4 ml of wine. 
To je podobno, kot če bi odrasli spil 4-22 ml piva ali 1-4 ml vina.
• loss or changed sense of taste; 
- odsotnost ali spremenjen občutek za okus;
1 See section 4.4: pancreatitis and lipids c. Description of selected adverse reactions 
1glejte poglavje 4.4: pankreatitis in lipidi c. Opis izbranih neželenih učinkov
Effects on the electrocardiogram 
Učinki na elektrokardiogram
2 years 
2 leti.
After multiple dosing, less than 3% of the lopinavir dose is excreted unchanged in the urine. 
Po večkratnem odmerjanju se manj kot 3 % odmerka lopinavirja izloči nespremenjenega v urinu.
• a sound in one ear or both ears, such as buzzing, ringing or whistling; 
- zvoki v enem ali v obeh ušesih, kot so brenčanje, zvonenje ali žvižganje;
* n = 18 for Cmax 
* n = 18 za Cmax
Patients should be closely monitored for signs related to venetoclax toxicities. 
Bolnike je potrebno pozorno spremljati glede znakov povezanih s toksičnostjo venetoklaksa.
Your doctor will discuss with you and determine which medicines are best for you. 
Vaš zdravnik se bo pogovoril z vami in bo presodil, katera zdravila so za vas najprimernejša.
• You can still pass on HIV when taking this medicine, although the risk is lowered by effective antiretroviral therapy. 
- Še vedno lahko prenašate HIV medtem, ko jemljete to zdravilo, čeprav je tveganje zmanjšano z učinkovitim protivirusnim zdravljenjem.
Moreover, in case of withdrawal of glucocorticoids progressive dose reduction may have to be performed over a longer period. 
Poleg tega je lahko v primeru opustitve glukokortikoidov potrebno postopno zmanjševanje odmerka v daljšem obdobju.
For erectile dysfunction: 
Za erektilno disfunkcijo:
Effects of food on oral absorption 
Učinek hrane na peroralno absorpcijo
Administration of activated charcoal may also be used to aid in removal of unabsorbed active substance. 
Kot pomoč za odstranitev neabsorbirane zdravilne učinkovine se lahko uporabi tudi aktivno oglje.
If an erection lasts longer than 4 hours, you should get medical help immediately to avoid permanent damage to your penis. 
Če erekcija traja več kot 4 ure, takoj potrebujete zdravniško pomoč, da bi preprečili trajno okvaro spolnega uda.
The frequency category includes all reported events of moderate to severe intensity, regardless of the individual causality assessment. 
Kategorija pogostnosti vključuje vse zmerne do hude neželene učinke, o katerih so poročali, ne glede na individualno oceno vzroka.
Check with your pharmacist that you have the correct size of syringe. 
S farmacevtom preverite, da imate pravo velikost brizge.
• low number of red blood cells, low number of white blood cells which are usually used to fight infection; 
- nizko število rdečih krvničk, nizko število belih krvničk, ki so potrebne za boj proti okužbi;
Voriconazole: Concentrations may be decreased. 
Vorikonazol: koncentracije se lahko znižajo.
Lopinavir/ritonavir has been evaluated in over 3000 women during pregnancy, including over 1000 during the first trimester. 
Lopinavir/ritonavir sta bila ocenjena pri preko 3000 ženskah med nosečnostjo, vključno s preko 1000 ženskami v prvem trimesečju nosečnosti.
Known and theoretical interactions with selected antiretrovirals and non-antiretroviral medicinal products are listed in the table below. 
Znana in teoretična medsebojna delovanja z izbranimi protiretrovirusnimi in neprotiretrovirusnimi zdravili so navedena v spodnji preglednici.
Important information 
Pomembni podatki
Currently available data are described in section 5.2 but no recommendation on the posology can be made. 
Trenutno razpoložljivi podatki so opisani v poglavju 5.2, vendar priporočila o odmerjanju ni mogoče podati.
Wash the plunger and the syringe with washing up liquid and warm water as soon as you can; you may soak both in soapy water for up to 15 minutes. 
Bat in brizgo čim prej operite s tekočino za pomivanje posode in toplo vodo; oba lahko tudi do 15 minut namakate v milnati vodi.
The median follow-up was 48 weeks in Cohort I and 72 weeks in Cohort II. 
Mediana spremljanja bolnikov je bila 48 tednov v kohorti I in 72 tednov v kohorti II.
Body Surface Area (m2) 
Telesna površina (m2)
DM-6705 (delamanid active metabolite): 
DM-6705 (aktivni presnovek delamanida):
Studies in rats revealed that lopinavir is excreted in the milk. 
Študije pri podganah so pokazale, da se lopinavir izloča v mleku.
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you or your child. 
Pred začetkom jemanja zdravila natančno preberite navodilo, ker vsebuje za vas ali vašega otroka pomembne podatke!
It is therefore important that you remain under the supervision of your doctor while taking Kaletra. 
Zato je pomembno, da med jemanjem zdravila Kaletra ostanete pod nadzorstvom svojega zdravnika.
Virologic Response of Study Subjects at Week 48 and Week 96 Week 48 
Virološki odziv preiskovancev v študiji po 48 in 96 tednih 48. teden
Based on the data mentioned, the malformative risk is unlikely in humans. 
Na osnovi omenjenih podatkov je tveganje za pojav anomalij pri ljudeh malo verjetno.
These medicinal products include: 
Med takšna zdravila spadajo:
Medicinal products that are contraindicated specifically due to the expected magnitude of interaction and potential for serious adverse events are listed in section 4.3. 
Zdravila, ki so kontraindicirana prav zaradi pričakovane izrazitosti interakcije in potenciala za resne neželene učinke, so navedena v poglavju 4.3.
The mechanism of this interaction may result from inhibition of transport proteins. 
Mehanizem tega medsebojnega delovanja je morda posledica zavrtja transportnih beljakovin.
The following events have been identified as adverse reactions. 
Opisani so bili naslednji neželeni dogodki.
Treatment of overdose with Kaletra is to consist of general supportive measures including monitoring of vital signs and observation of the clinical status of the patient. 
Zdravljenje prevelikega odmerjanja zdravila Kaletra mora obsegati splošne podporne ukrepe, vključno z nadziranjem vitalnih znakov in opazovanjem bolnikovega kliničnega stanja.
It is not known whether this medicinal product is excreted in human milk. 
Ni znano, ali se to zdravilo izloča v materinem mleku tudi pri ljudeh.
Pre-dose lopinavir concentrations decline with time during multiple dosing, stabilising after approximately 10 days to 2 weeks. 
Predodmerna koncentracija lopinavirja med večkratnim odmerjanjem s časom upada in se stabilizira po približno 10 dneh do 2 tednih.
Use in children 
Uporaba pri otrocih
Safety, efficacy and pharmacokinetic profiles of the two dose regimens were assessed after 3 weeks of therapy in each patient. 
Varnost, učinkovitost in farmakokinetične profile obeh odmernih shem so pri vsakem bolniku ocenili po 3 tednih zdravljenja.
Thereby, increasing the risk of extreme sedation and respiratory depression from these agents. 
Zaradi tega večje tveganje skrajne sedacije in depresije dihanja zaradi teh zdravil.
After removing the air bubbles, look at the dose mark. 
Po odstranitvi zračnih mehurčkov, poglejte kolikšen je odmerek.
Make sure you have the correct syringe for the dose. 
Prepričajte se, da imate pravo brizgo za odmerek.
Since these patients had not previously been exposed to either Kaletra or efavirenz, part of the response may be attributed to the antiviral activity of efavirenz, particularly in patients harbouring highly lopinavir resistant virus. 
Ker ti bolniki predhodno niso bili izpostavljeni niti zdravilu Kaletra niti efavirenzu, je del odziva mogoče pripisati protivirusni dejavnosti efavirenza, zlasti pri bolnikih, ki so imeli proti lopinavirju zelo odporen virus.
Your doctor will advise on the number of tablets to be taken. 
Zdravnik vam bo svetoval, koliko tablet morate vzeti.
The recommended dose of 533/133 mg or 6.5 ml twice daily should not be exceeded. 
Priporočenega odmerka 533/133 mg ali 6,5 ml dvakrat na dan se ne sme preseči.
Further stratification within each group was 1:1 (tablet versus soft capsule). 
Dodatna stratifikacija znotraj posamezne skupine je bila narejena v razmerju 1:1 (tablete v primerjavi z mehkimi kapsulami).
*Proportion of subjects who had HIV-1 < 400 copies/ml and had remained on study treatment 
*Delež preiskovancev, ki so imeli HIV-1 < 400 kopij/ml in so ostali na zdravljenju v študiji
Kaletra does this by slowing down the spread of the infection in your body. 
Zdravilo Kaletra to doseže tako, da upočasni širjenje okužbe v telesu.
Dosage adjustment for midazolam should be considered especially if more than a single dose of midazolam is administered. 
V poštev pride prilagoditev odmerjanja midazolama, zlasti če je uporabljen več kot en sam odmerek midazolama.
• Do not take Kaletra if you are currently taking avanafil or vardenafil. 
- Ne jemljite zdravila Kaletra, če trenutno jemljete avanafil ali vardenafil.
(equivalent to 245 mg tenofovir disoproxil) 
(ekvivalentno 245 mg dizoproksiltenofovirata)
These effects have been assumed to be caused by electrolyte disturbance. 
Domnevno so vzrok tega elektrolitske motnje.
Sedatives/hypnotics 
Sedativi/hipnotiki
It should be kept in mind that the twice weekly dosage of 150 mg may not provide an optimal exposure to rifabutin thus leading to a risk of rifamycin resistance and a treatment failure. 
Treba je upoštevati, da odmerek rifabutina 150 mg 2-krat na teden ne omogoča optimalne izpostavljenosti rifabutinu, kar vodi k tveganju za rezistenco na rifamicin in k neuspešnemu zdravljenju.
The extent of increase depends on the timing of ritonavir administration. 
Obseg povečanja je odvisen od časa uporabe ritonavirja.
At steady state, lopinavir is approximately 98 − 99% bound to serum proteins. 
V stanju dinamičnega ravnovesja je lopinavir približno 98- do 99-odstotno vezan na serumske beljakovine.
• feeling tired, lack of strength and energy, headache including migraine; 
- utrujenost, pomanjkanje moči in energije, glavobol vključno z migreno;
Two pack sizes are available: 
Na voljo sta dve pakiranji:
Fluticasone propionate, 50 µg intranasal 4 times daily: 
Flutikazonpropionat, 50 µg intranazalno 4-krat na dan:
If you are currently taking any of these medicines, ask your doctor about making necessary changes either in the treatment for your other condition(s) or in your antiretroviral treatment. 
Če trenutno jemljete katero od teh zdravil, se z zdravnikom pogovorite o potrebni spremembi zdravljenja drugih bolezenskih stanj ali protiretrovirusnega zdravljenja.
No data are available in patients with severe hepatic impairment. 
Nobenih podatkov ni na voljo pri bolnikih s hudo jetrno okvaro.
Kaletra may cause changes in your heart rhythm and the electrical activity of your heart. 
Zdravilo Kaletra lahko povzroči spremembe v srčnem ritmu in električni aktivnosti srca.
High doses of ketoconazole and itraconazole (> 200 mg/day) are not recommended. 
Veliki odmerki ketokonazola in itrakonazola (> 200 mg/dan) niso priporočljivi.
The 16 viruses that displayed > 20-fold change in susceptibility all contained mutations at positions 10, 54, 63 plus 82 and/or 84. 
Vseh 16 virusov, ki so pokazali > 20-kratno spremembo v občutljivosti, je imelo mutacije na položajih 10, 54, 63 ter dodatno 82 in/ali 84.
Kaletra has not specifically been tested for its possible effects on the ability to drive a car or operate machines. 
Zdravila Kaletra niso posebej preizkušali glede možnih učinkov na sposobnost za upravljanje vozil ali delo s stroji.
While effective viral suppression with antiretroviral therapy has been proven to substantially reduce the risk of sexual transmission, a residual risk cannot be excluded. 
Čeprav je bilo dokazano, da učinkovito zaviranje virusov s protivirusnim zdravljenjem bistveno zmanjša tveganje za spolni prenos, preostalo tveganje ne more biti izključeno.
It is unknown whether the combination of Kaletra causes a similar increase in trazodone exposure. 
Ni znano, ali tudi zdravilo Kaletra podobno poveča izpostavljenost trazodonu.
In post-marketing surveillance through the Antiretroviral Pregnancy Registry, established since January 1989, an increased risk of birth defects exposures with Kaletra has not been reported among over 1000 women exposed during the first trimester. 
V nadzoru v obdobju trženja s pomočjo Protiretrovirusnega nosečnostnega registra, ki je vzpostavljen od januarja 1989, niso poročali o povečanem tveganju prirojenih napak med 1000 ženskami, ki so bile izpostavljene v prvem trimesečju.
• decreased ability of the body to handle sugar including diabetes mellitus, weight loss; 
- zmanjšana sposobnost telesa za uravnavanje sladkorja vključno s sladkorno boleznijo, znižanje telesne mase;
Overall failure rate combining the treatment differences across age strata, weighted by the precision of the estimate within each age stratum p=0.015 (Cohort I); p< 0.001 (Cohort II) 
Celokupni delež neuspeha z upoštevanjem razlik med zdravljenji pri različnih starostnih skupinah, uteženih z natančnostjo ocene znotraj vsake starostne skupine, je bil p=0,015 (kohorta I); p< 0,001 (kohorta II).
Mutations V82A, I54V and M46I emerged most frequently. 
Najpogosteje so se pojavile mutacije V82A, I54V in M46I.
What Kaletra is and what it is used for 
Kaj je zdravilo Kaletra in za kaj ga uporabljamo
It is believed that these symptoms are due to an improvement in the body's immune response, enabling the body to fight infections that may have been present with no obvious symptoms. 
Predvideva se, da so simptomi posledica izboljšanja imunskema sistema, ki omogoča telesu, da se bori proti infekcijam, ki so lahko bile prisotne brez očitnih simptomov.
+ 4% (95% CI: -1, 9) (n=19) 
+ 4 % (95 % IZ: -1, 9) (n=19)
No clinical relevant interaction expected. 
klinično pomembnih medsebojnih delovanj ni pričakovati.
Patients had a mean age of 5 years (range 6 months to 12 years) with 14 patients less than 2 years old and 6 patients one year or less. 
Povprečna starost bolnikov je bila 5 let (razpon: od 6 mesecev do 12 let); 14 bolnikov je bilo mlajših od 2 let in 6 jih je bilo starih eno leto ali manj.
The prevalence of birth defects after any trimester exposure to lopinavir is comparable to the prevalence observed in the general population. 
Pojavnost prirojenih napak po izpostavljenosti lopinavirju v kateremkoli trimesečju je primerljiva s pojavnostjo, opaženo v splošni populaciji.
At least 13 lopinavir oxidative metabolites have been identified in man. 
Pri ljudeh je identificiranih vsaj 13 oksidativnih presnovkov lopinavirja.
Therefore, Kaletra can be started safely 2 weeks after cessation of St John's wort. 
Kaletra mogoče varno začeti uporabljati 2 tedna po prenehanju jemanja šentjanževke.
Mean (%CV) Steady-State Pharmacokinetic Parameters of Lopinavir in HIV-Infected Pregnant Women 
Srednji (%CV) farmakokinetični parametri v stanju ravnovesja za lopinavir pri nosečnicah, okuženih s HIV
• a flare-up of symptoms related to an inactive infection in your body (immune reconstitution); 
- zmanjšano delovanje testisov; - izbruh simptomov, povezanih z neaktivno okužbo v vašem telesu (imunska rekonstitucija);
Therefore, this co-administration should be avoided unless judged strictly necessary (see section 4.5). 
Zato naj se taka sočasna uporaba izogiba, razen če se presodi, da je absolutno potrebna (glejte poglavje 4.5).
Important information about some of the ingredients of Kaletra 
Pomembne informacije o nekaterih sestavinah zdravila Kaletra
PR interval prolongation 
Podaljšanje intervala PR
The safety and efficacy of Kaletra in children aged less than 2 years have not yet been established. 
Varnost in učinkovitost uporabe zdravila Kaletra pri otrocih, mlajših od 2 let še ni bila ugotovljena.
Ask your pharmacist how to throw away medicines you no longer use. 
O načinu odstranjevanja zdravila, ki ga ne uporabljate več,
The dose increase did not result in a significant increase in the plasma lopinavir concentration. 
Povečanje odmerka ni povzročilo pomembnega zvišanja plazemske koncentracije lopinavirja.
Appropriate precautions (e.g. use of a condom) should be taken to prevent passing on the disease through sexual contact. 
Upoštevati morate ustrezne previdnostne ukrepe (npr. uporaba kondoma), da ne pride do prenosa bolezni s spolnim stikom.
Special attention should be given to accurate calculation of the dose of Kaletra, transcription of the medication order, dispensing information and dosing instructions to minimize the risk for medication errors and overdose. 
Posebno pozornost je treba nameniti natančnemu izračunu odmerka zdravila Kaletra, prepisu naročila za zdravilo, informacijam za izdajo zdravila in navodilom za odmerjanje, da bi čim bolj zmanjšali tveganje za napake pri uporabi in preveliko odmerjanje.