natgillin/translations-raw huggingface dataset:
Once-a-day dosing of CIALIS both for the treatment of erectile dysfunction and benign prostatic hyperplasia has not been evaluated in patients with hepatic impairment; therefore, if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician (see sections 4.4 and 5.2). 
Pri bolnikih z okvaro jeter niso ocenjevali odmerjanja zdravila CIALIS enkrat na dan za zdravljenje erektilne disfunkcije in benigne hiperplazije prostate; torej, v kolikor ga predpišemo, naj zdravnik, ki zdravilo predpiše, skrbno ovrednoti razmerje med koristmi in tveganjem pri posamezniku (glejte poglavji 4.4 in 5.2).
Each coated tablet contains 87 mg of lactose (as monohydrate). 
Ena obložena tableta vsebuje 87 mg laktoze (v obliki monohidrata).
Light orange-yellow and almond shaped tablets, marked "C 2 ½" on one side. 
Tablete svetlo oranžne barve in mandljeve oblike, z oznako "C 2 ½" na eni strani.
There is limited clinical data on the safety of CIALIS in patients with severe hepatic insufficiency (ChildPugh Class C). 
O varnosti zdravila CIALIS pri bolnikih s hudo insuficienco jeter (razred C po Child-Pughu) obstajajo le omejeni klinični podatki.
Musculoskeletal, connective tissue and bone disorders Back pain, 
Bolezni mišično-skeletnega sistema in vezivnega tkiva bolečina v hrbtu, mialgija, bolečina v okončinah
Once-a-day dosing has not been evaluated in patients with hepatic impairment; therefore, if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician (see sections 4.4 and 5.2). 
Pri bolnikih z okvaro jeter niso ocenjevali odmerjanja enkrat na dan; torej, v kolikor ga predpišemo, naj zdravnik, ki zdravilo predpiše, skrbno ovrednoti razmerje med koristmi in tveganjem pri posamezniku (glejte poglavji 4.4 in 5.2).
CIALIS contains lactose: If you have an intolerance to some sugars, contact your doctor before taking this medicine. 
Če ne prenašate nekaterih sladkorjev, se posvetujte s svojim zdravnikom pred jemanjem tega zdravila.
- The other ingredients are: Tablet core: lactose monohydrate (see end of section 2), croscarmellose sodium, hydroxypropylcellulose, microcrystalline cellulose, sodium laurilsulfate, magnesium stearate. 
Jedro tablete: laktoza monohidrat (glejte zaključek poglavja 2), premreženi natrijev karmelozat, hidroksipropilceluloza, mikrokristalna celuloza, natrijev lavrilsulfat, magnezijev stearat.
CIALIS 2.5 mg is a light orange-yellow film-coated tablet in the shape of an almond and has "C 2 ½" marked on one side. 
Tablete CIALIS 2,5 mg so svetlo oranžno-rumene filmsko obložene tablete v obliki mandlja in imajo na eni strani oznako "C 2 ½".
Each coated tablet contains 121 mg lactose (as monohydrate). 
Ena obložena tableta vsebuje 121 mg laktoze (v obliki monohidrata).
Decreased or sudden hearing loss has been noted in some patients taking tadalafil. 
Pri nekaterih bolnikih, ki so jemali tadalafil, so opazili poslabšanje ali nenadno izgubo sluha.
Each coated tablet contains 233 mg lactose (as monohydrate). 
Ena obložena tableta vsebuje 233 mg laktoze (v obliki monohidrata).
Alcohol concentrations (mean maximum blood concentration 0.08 %) were not affected by coadministration with tadalafil (10 mg or 20 mg). 
Sočasno dajanje tadalafila (10 ali 20 mg) ni vplivalo na koncentracije alkohola (povprečna maksimalna koncentracija v krvi 0,08 %).
INFORMATION IN BRAILLE cialis 10 mg 
PODATKI V BRAILLOVI PISAVI cialis 10 mg
INFORMATION IN BRAILLE cialis 5 mg 
PODATKI V BRAILLOVI PISAVI cialis 5 mg
Uncommon (seen in 1 to 10 in every 1,000 patients) - dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. 
težave pri dihanju, prisotnost krvi v urinu, podaljšana erekcija, občutek razbijanja srca, hitro bitje srca, visok krvni tlak, nizek krvni tlak, krvavitve iz nosu, zvonjenje v ušesih, otekanje dlani, stopal ali gležnjev in občutek utrujenosti.
MARKETING AUTHORISATION NUMBER(S) EU/1/02/237/007-008, 010 
ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/02/237/007-008, 010
How to store CIALIS 
Shranjevanje zdravila CIALIS
Each tablet contains 5 mg of tadalafil. 
Ena tableta vsebuje 5 mg tadalafila.
- a severe kidney problem. 
- resne težave z ledvicami.
Each coated tablet contains 170 mg lactose (as monohydrate). 
Ena obložena tableta vsebuje 170 mg laktoze (v obliki monohidrata).
If CIALIS is prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician. 
Če zdravnik predpiše zdravilo CIALIS, mora skrbno ovrednotiti razmerje med koristmi in tveganjem pri posamezniku.
CIALIS is a treatment for adult men with erectile dysfunction. 
Kaj je zdravilo CIALIS in za kaj ga uporabljamo Zdravilo CIALIS je namenjeno zdravljenju odraslih moških z erektilno disfunkcijo.
Light yellow and almond shaped tablets, marked "C 5" on one side. 
Tablete svetlo rumene barve in mandljeve oblike, z oznako “C 5” na eni strani.
Each tablet contains 10 mg of tadalafil. 
Ena tableta vsebuje 10 mg tadalafila.
This is when the prostate gland gets bigger with age. 
Pri tem obolenju se prostata z leti povečuje.
If CIALIS is prescribed once-a-day, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician. 
Če zdravnik predpiše zdravilo CIALIS za odmerjanje enkrat na dan, mora skrbno ovrednotiti razmerje med koristmi in tveganjem pri posamezniku.
For CIALIS on demand, three clinical studies were conducted in 1054 patients in an at-home setting to define the period of responsiveness. 
Opravljene so bile tri klinične študije za določitev obdobja odzivnosti na zdravilo CIALIS, v katere je bilo vključenih 1054 bolnikov v domačem okolju.
Men with hepatic impairment 
Moški z okvaro jeter
NAME OF THE MEDICINAL PRODUCT CIALIS 20 mg tablets tadalafil 
IME ZDRAVILA CIALIS 20 mg tablete tadalafil
QUALITATIVE AND QUANTITATIVE COMPOSITION CIALIS 10 mg film-coated tablets Each tablet contains 10 mg tadalafil. 
CIALIS 10 mg filmsko obložene tablete Ena tableta vsebuje 10 mg tadalafila.
Although specific interactions have not been studied, other protease inhibitors, such as saquinavir, and other CYP3A4 inhibitors, such as erythromycin, clarithromycin, itraconazole and grapefruit juice should be co-administered with caution as they would be expected to increase plasma concentrations of tadalafil (see section 4.4). 
Čeprav specifičnih medsebojnih delovanj niso preučevali, je potrebno druge zaviralce proteaze, kot je sakvinavir, ter druge zaviralce CYP3A4, kot so eritromicin,
Do not take CIALIS if you: 
Kaj morate vedeti, preden boste vzeli zdravilo CIALIS Ne jemljite zdravila CIALIS, če:
Once-a-day dosing of tadalafil is not recommended in patients with severe renal impairment (see sections 4.4 and 5.2). 
Pri bolnikih s hudo okvaro ledvic je največji priporočeni odmerek 10 mg. Odmerjanje tadalafila enkrat na dan ni priporočljivo za bolnike s hudo okvaro ledvic (glejte poglavji 4.4 in 5.2).
It is not known if CIALIS is effective in patients who have undergone pelvic surgery or radical non-nervesparing prostatectomy. 
učinkovito pri bolnikih po operacijah v medenici ali po radikalni prostatektomiji brez ohranjanja živcev.
MARKETING AUTHORISATION NUMBER(S) EU/1/02/237/001-005, 009 
ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/02/237/001-005, 009
Tadalafil at doses of 2 to 100 mg has been evaluated in 16 clinical studies involving 3250 patients, including patients with erectile dysfunction of various severities (mild, moderate, severe), etiologies, ages (range 21-86 years), and ethnicities. 
3250 bolnikov, vključno z bolniki z erektilno disfunkcijo različnih resnosti (blaga, zmerna, huda), etiologij, starosti (razpon 21-86 let) in narodnosti.
Rare (seen in 1 to 10 in every 10,000 patients) - fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. 
- omedlevica, epileptični napadi in začasna izguba spomina, otekanje vek, rdeče oči, nenadno poslabšanje ali izguba sluha, koprivnica (srbeče rdeče maroge na površini kože), krvavitev iz penisa,
Three clinical studies were conducted in 1054 patients in an at-home setting to define the period of responsiveness to CIALIS on demand. 
Opravljene so bile tri klinične študije za določitev obdobja odzivnosti na zdravilo CIALIS zaužito po potrebi, v katerih je bilo vključenih 1054 bolnikov v domačem okolju.
MARKETING AUTHORISATION NUMBER(S) EU/1/02/237/006 
ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/02/237/006
Visual defects and cases of NAION have been reported in connection with the intake of CIALIS and other PDE5 inhibitors. 
Vid V povezavi z jemanjem zdravila CIALIS in drugih zaviralcev PDE5 so poročali o okvarah vida in primerih NAION.
NAME OF THE MEDICINAL PRODUCT CIALIS 2.5 mg film-coated tablets 
IME ZDRAVILA CIALIS 2,5 mg filmsko obložene tablete
For oral once-a-day use. 
Za peroralno uporabo enkrat na dan.
CIALIS 20 mg film-coated tablets 
CIALIS 20 mg filmsko obložene tablete tadalafil
MARKETING AUTHORISATION NUMBER(S) EU/1/02/237/001 
ŠTEVILKA(E) DOVOLJENJA(DOVOLJENJ) ZA PROMET EU/1/02/237/001
CIALIS 10 mg film-coated tablets 
CIALIS 10 mg filmsko obložene tablete tadalafil
MARKETING AUTHORISATION NUMBER(S) EU/1/02/237/002-005, 009 
ŠTEVILKA(E) DOVOLJENJA(DOVOLJENJ) ZA PROMET EU/1/02/237/002-005, 009
NAME OF THE MEDICINAL PRODUCT CIALIS 10 mg tablets tadalafil 
IME ZDRAVILA CIALIS 10 mg tablete tadalafil
A medical history and physical examination should be undertaken to diagnose erectile dysfunction and determine potential underlying causes, before pharmacological treatment is considered. 
Preden začnemo razmišljati o farmakološkem zdravljenju, je za diagnozo erektilne disfunkcije in določitev možnih temeljnih vzrokov potrebno vzeti anamnezo in pregledati bolnika.
NAME OF THE MEDICINAL PRODUCT CIALIS 5 mg film-coated tablets 
IME ZDRAVILA CIALIS 5 mg filmsko obložene tablete
NAME OF THE MEDICINAL PRODUCT CIALIS 2.5 mg tablets tadalafil 
IME ZDRAVILA CIALIS 2,5 mg tablete tadalafil
What CIALIS looks like and contents of the pack CIALIS 20 mg is a yellow film-coated tablet in the shape of an almond and has "C 20" marked on one side. 
Tablete CIALIS 20 mg so rumene filmsko obložene tablete v obliki mandlja in imajo na eni strani oznako "C 20".
CIALIS 2.5 mg film-coated tablets Tadalafil 
CIALIS 2,5 mg filmsko obložene tablete tadalafil
General disorders and administration site conditions Chest pain1, Peripheral oedema, Fatigue 
Splošne težave in spremembe na mestu aplikacije bolečina v prsnem košu1, periferni edem, utrujenost otečen obraz2, nenadna srčna smrt1,2
See leaflet for further information. 
laktoza Za nadaljnje informacije glejte navodilo za uporabo!
CIALIS 5 mg film-coated tablets Tadalafil 
CIALIS 5 mg filmsko obložene tablete tadalafil
Once-a-day administration either for the treatment of erectile dysfunction or benign prostatic hyperplasia has not been evaluated in patients with hepatic insufficiency. 
Pri bolnikih z jetrno insufienco niso ocenjevali odmerjanja enkrat na dan za zdravljenje erektilne disfunkcije ali benigne hiperplazije prostate.
Warnings and precautions Talk to your doctor before taking CIALIS. 
Pred začetkom jemanja zdravila CIALIS se posvetujte z zdravnikom.
NAME OF THE MEDICINAL PRODUCT CIALIS 5 mg tablets tadalafil 
IME ZDRAVILA CIALIS 5 mg tablete tadalafil
What CIALIS looks like and contents of the pack CIALIS 10 mg is a light yellow film-coated tablet in the shape of an almond and has "C 10" marked on one side. 
Tablete CIALIS 10 mg so svetlo rumene filmsko obložene tablete v obliki mandlja in imajo na eni strani oznako "C 10".
What CIALIS looks like and contents of the pack CIALIS 5 mg is a light yellow film-coated tablet in the shape of an almond and has "C 5" marked on one side. 
Tablete CIALIS 5 mg so svetlo rumene filmsko obložene tablete v obliki mandlja in imajo na eni strani oznako "C 5".
Visual field defect, Swelling of eyelids, Conjunctival hyperaemia, Nonarteritic anterior ischemic optic neuropathy (NAION) 2, Retinal vascular occlusion2 
nearterična anteriorna ishemična optična nevropatija (NAION) zapora retinalnih žil2
Yellow and almond shaped tablets, marked "C 20" on one side. 
CIALIS 20 mg filmsko obložene tablete Tablete rumene barve in mandljeve oblike, z oznako "C 20" na eni strani.
Tadalafil is > 10,000-fold more potent for PDE5 than for PDE1, PDE2, and PDE4, enzymes which are found in the heart, brain, blood vessels, liver, and other organs. 
PDE4, encime, ki se nahajajo v srcu, možganih, krvnih žilah, jetrih in drugih organih.
Once-a-day administration has not been evaluated in patients with hepatic insufficiency. 
Pri bolnikih z jetrno insuficienco niso ocenjevali odmerjanja enkrat na dan.
In patients receiving concomitant antihypertensive medicinal products, tadalafil may induce a blood pressure decrease. 
Tadalafil lahko povzroči znižanje krvnega tlaka pri bolnikih, ki sočasno prejemajo antihipertenzive.
Hepatic insufficiency 
Insufienca ledvic
Stroke1 (including haemorrhagic events), Syncope, Transient ischaemic attacks1, Migraine2, Seizures2, Transient amnesia 
migrena2, epileptični napadi2, prehodna amnezija
NAME OF THE MEDICINAL PRODUCT CIALIS 20 mg film-coated tablets tadalafil 
Navodilo za uporabo CIALIS 20 mg filmsko obložene tablete tadalafil
Respiratory, thoracic and mediastinal disorders Nasal congestion 
Žilne bolezni zardevanje hipotenzija3 hipertenzija Bolezni dihal, prsnega koša in mediastinalnega prostora nosna kongestija dispneja, epistaksa
Cardiac disorders1 
Srčne bolezni1
A. MANUFACTURER(S) RESPONSIBLE FOR BATCH RELEASE Name and address of the manufacturers responsible for batch release Lilly S.A., Avda. 
Ime in naslov izdelovalcev, odgovornih za sproščanje serije
NAME OF THE MEDICINAL PRODUCT CIALIS 10 mg film-coated tablets tadalafil 
Navodilo za uporabo CIALIS 10 mg filmsko obložene tablete tadalafil
Light yellow and almond shaped tablets, marked "C 10" on one side. 
CIALIS 10 mg filmsko obložene tablete Tablete svetlo rumene barve in mandljeve oblike, z oznako "C 10" na eni strani.
Nervous system disorders 
erektilno disfunkcijo.
There is limited clinical data on the safety of single-dose administration of CIALIS in patients with severe hepatic insufficiency (Child-Pugh Class C). 
Pri bolnikih s hudo jetrno insuficienco (razred C po Child-Pughu) je na voljo le malo kliničnih podatkov o varnosti zdravila CIALIS pri enkratnem odmerjanju.
NAME OF THE MEDICINAL PRODUCT CIALIS 2.5 mg film-coated tablets tadalafil 
Navodilo za uporabo CIALIS 2,5 mg filmsko obložene tablete tadalafil
Before treatment with CIALIS 
Druga zdravila in zdravilo CIALIS
LIST OF EXCIPIENTS lactose 
Acetilsalicilna kislina
Posology 
UPORABE
NAME OF THE MEDICINAL PRODUCT CIALIS 5 mg film-coated tablets tadalafil 
Navodilo za uporabo CIALIS 5 mg filmsko obložene tablete tadalafil
4 and 5.2). 
(glejte poglavje 4.3).
Common (seen in 1 to 10 in every 100 patients) - headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion and indigestion. 
- glavobol, bolečina v hrbtu, bolečine v mišicah, bolečina v rokah in nogah, zardevanje v obraz,
These events are usually transient. 
Ti dogodki so navadno prehodni.
The mechanism leading to this reaction is unknown. 
Mehanizem, ki privede do te reakcije, ni znan.
There is no specific antidote. 
Specifičnega antidota ni na voljo.
In addition, it is especially important to tell your doctor if you are also using any of the following medicines: 
Poleg tega je posebej pomembno, da zdravniku poveste, če jemljete tudi katero od naslednjih zdravil:
Adults and children older than 1 year 
Odrasli in otroci, starejši od enega leta
Not known (frequency cannot be estimated from the available data): 
Neznana (pogostnosti iz razpoložljivih podatkov ni mogoče oceniti):
You may be more susceptible to infections. 
Morda ste dovzetnejši za okužbe.
Acute pancreatitis has developed in less than 10 % of patients. 
Akutni pankreatitis se je razvil pri manj kot 10 % bolnikov.
Treatment is symptomatic and supportive. 
Zdravljenje je simptomatsko in podporno.
The causes of these nervous system disorders are unclear. 
Vzroki teh bolezni živčevja niso jasni.
If necessary, your doctor will treat your symptoms and will give you supportive care. 
Če bo treba, bo zdravnik zdravil vaše simptome in vam zagotovil podporno zdravljenje.
Results of this study are summarised in table 3: 
Rezultati te študije so povzeti v preglednici 3:
It should only be given in a hospital setting where appropriate resuscitation equipment is available. 
Dajati se sme le v bolnišnicah, kjer je na voljo ustrezna oprema za reanimacijo.
Frequency and symptom 
Pogostnost in simptom
This effect was most prominent with a treatment interval of about 120 hours. 
Ta učinek je bil najizrazitejši pri intervalu okoli 120 ur med dajanjem zdravil.
As a precautionary measure it is recommended to wait for three months after completion of treatment. 
Kot previdnostni ukrep priporočajo, naj se počaka tri mesece po dokončanju zdravljenja.
MRD positive 
MRD negativna
Both procedures, however, do not allow for predicting accurately which patients will experience an allergic reaction. 
Vendar noben od teh postopkov ne omogoča natančne napovedi, pri katerih bolnikih se bo pojavila alergijska reakcija.
Elderly Limited data are available for the treatment of patients older than 65 years of age. 
Za zdravljenje bolnikov, starejših od 65 let, je na voljo malo podatkov.
Asparagine depletion in serum was complete in 11 of 12 patients (92%). 
Izčrpanje asparagina v serumu je bilo popolno pri 11 bolnikih od 12 bolnikov (92 %).
E-mail: contact@medac.de 
contact@medac.de
Approximately half of the thrombotic events is localised in cerebral vessels. 
Približno polovica trombotičnih dogodkov je lokalizirana v možganskih žilah.
A previous intracutaneous test or a small intravenous test dose can be used. 
Lahko uporabimo predhoden intrakutani test ali majhen intravenski testni odmerek.
Number of patients 
Število bolnikov
Results are shown in table 4. 
Rezultati so navedeni v preglednici 4.
Area under the curve (AUC0-72h) 
površina pod krivuljo (AUC0-72h)
One unit (U) is defined as the quantity of enzyme required to liberate one µmol ammonia per minute at pH 7.3 and 37°C. 
Ena enota (e.) je opredeljena kot količina encima, ki je potrebna, da sprosti en µmol amoniaka na minuto pri pH 7,3 in 37 °C.
You may be given anti-allergic medicines and, if necessary, medicines to stabilise your circulation. 
Mogoče boste dobili zdravila proti alergiji in, če bo treba, zdravila za stabilizacijo krvnega obtoka.
All 12 patients (100 %) were in CR after induction treatment. 
Vseh 12 bolnikov (100 %) je bilo po indukcijskem zdravljenju v popolni remisiji.
Read all of this leaflet carefully before you are given this medicine because it contains important information for you. 
Preden vam dajo to zdravilo, natančno preberite navodilo, ker vsebuje za vas pomembne podatke!
The duration of treatment depends on the specific chemotherapy protocol that is used to treat your disease. 
Trajanje zdravljenja je odvisno od posebnega kemoterapevtskega protokola, ki se uporablja za zdravljenje vaše bolezni.
The risk of thrombosis seems to be higher than the risk of bleeding. 
Zdi se, da je nevarnost tromboze večja kot nevarnost krvavitve.
The syndrome is generally self-limiting. 
Sindrom je navadno samoomejujoč.
For storage conditions after reconstitution and dilution of the medicinal product, see section 6.3. 
Za pogoje shranjevanja po rekonstituciji in razredčenju zdravila glejte poglavje 6.3.
• if you are allergic to asparaginase or to any of the other ingredients of this medicine (listed in section 6), 
• če ste alergični na asparaginazo ali katero koli sestavino tega zdravila (navedeno v poglavju 6),
Since serum protein is important for the binding and transport function of some active substances, the serum protein level should be monitored regularly. 
Ker so serumske beljakovine pomembne za funkcijo vezave in transporta nekaterih zdravilnih učinkovin, je treba redno spremljati raven serumskih beljakovin.
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine. 
Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom, preden vzamete to zdravilo.
Tell your doctor immediately and stop taking Spectrila if you experience: 
Takoj obvestite zdravnika in prenehajte jemati zdravilo Spectrila, če se pojavijo:
Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); not known (cannot be estimated from the available data). 
Pogostnosti v tej preglednici so opredeljene z naslednjim dogovorom: zelo pogosti (≥1/10); pogosti (≥1/100 do <1/10); občasni (≥1/1.000 do <1/100); redki (≥1/10.000 do <1/1.000); zelo redki (< 1/10.000); neznana (ni mogoče oceniti iz razpoložljivih podatkov).
Thereafter, asparagine serum levels increased again and returned to normal values within 1 - 3 weeks. 
Nato se je raven serumskega asparagina spet zviševala in dosegla normalne vrednosti po 1-3 tednih.
Adults and other special populations 
Odrasli in druge posebne skupine bolnikov
CI = confidence interval; CSF = cerebrospinal fluid; MRD = minimal residual disease a 
CI = interval zaupanja; CSF = cerebrospinalna tekočina; MRD = minimalna rezidualna bolezen a
Plasma ammonia levels should be determined in all patients with unexplained neurologic symptoms or severe and prolonged vomiting. 
Koncentracijo amoniaka v plazmi je treba določiti pri vseh bolnikih z nepojasnjenimi nevrološkimi simptomi ali hudim in dolgotrajnim bruhanjem.
Therefore, they require asparagine which diffuses from the extracellular environment. 
Zato potrebujejo asparagin, ki difundira iz zunajceličnega okolja.
Increased blood sugar values may require treatment with intravenous fluids and/or insulin. 
Pri zvečanih vrednostih krvnega sladkorja bo morda potrebno zdravljenje z intravenskimi tekočinami in/ali insulinom.
There have been isolated reports of fatal outcomes. 
Obstajajo posamezna poročila o smrtnih izidih.
Spectrila will not be used: 
Zdravilo Spectrila se ne sme uporabiti:
However, treatment with other chemotherapeutic agents should also be taken into consideration. 
Vendar pa je treba razmisliti tudi o zdravljenju z drugimi kemoterapevtiki.
Very common Oedema, fatigue 
Zelo pogosti edem, utrujenost
What you need to know before you are given Spectrila 
Kaj morate vedeti, preden vam bodo dali zdravilo Spectrila
• The medicine also contains sucrose. 
• Zdravilo vsebuje tudi saharozo.
If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2 °C - 8 °C unless reconstitution/dilution has taken place in controlled and validated aseptic conditions. 
Če se zdravilo ne uporabi takoj, je za trajanje shranjevanja med uporabo in razmere shranjevanja pred uporabo odgovoren uporabnik, shranjevanje pa naj bi normalno ne trajalo dalj od 24 ur pri 2 °C - 8 °C, razen če sta bila rekonstitucija in razredčenje opravljena v kontroliranih in validirano aseptičnih razmerah.
- age 6 - 12 months: 
- starih 6-12 mesecev:
Table 4: Pharmacokinetic parameters of Spectrila in 14 children/adolescents 
Preglednica 4: Farmakokinetični parametri zdravila Spectrila pri 14 otrocih/mladostnikih
If the medicine is not used immediately, the user preparing this medicine is responsible for storage times and conditions to ensure sterility of the product. 
Če se zdravilo ne uporabi takoj, je za trajanje shranjevanja in razmere, s katerimi se zagotavlja sterilnost zdravila, odgovoren uporabnik, ki pripravlja to zdravilo.
The dose depends on your body surface area (BSA) which is calculated from your height and weight. 
Odmerek bo odvisen od velikosti vaše telesne površine, ki se izračuna iz vaše višine in telesne mase.