natgillin/translations-raw huggingface dataset:
Recombinant human EPO (epoetin zeta), expressed in Chinese hamster ovary cells, has a 165 amino acid sequence identical to that of human urinary EPO; the 2 are indistinguishable on the basis of functional assays. 
Rekombinantni humani EPO (epoetin zeta), izražen v ovarijskih celicah kitajskega hrčka, ima 165 aminokislin dolgo zaporedje, identično tistemu, ki ga ima EPO v človeškem urinu; teh 2 ni mogoče ločiti na podlagi funkcionalnih preskusov.
• If you are a patient with chronic renal failure, and particularly if you do not respond properly to Retacrit, your doctor will check your dose of Retacrit because repeatedly increasing your dose of Retacrit if you are not responding to treatment may increase the risk of having a problem of the heart or the blood vessels and could increase risk of myocardial infarction, stroke and death. 
• Če ste bolnik s kronično ledvično okvaro, zlasti če se na zdravilo Retacrit ne odzivate ustrezno, bo zdravnik spremljal vaš odmerek zdravila Retacrit, ker ponavljajoče se zviševanje odmerka zdravila Retacrit, če se na zdravljenje ne odzivate, lahko poveča tveganje za težave s srcem ali krvnimi žilami in lahko poveča tveganje za srčni infarkt, možgansko kap in smrt.
• Your doctor will order blood tests, and may adjust the dose, depending on how your anaemia responds to Retacrit treatment. 
• Vaš zdravnik bo naročil krvne preiskave in morda prilagodil odmerek, odvisno od tega, kako se anemija odziva na zdravljenje z zdravilom Retacrit.
• epileptic seizures or fits 
• epileptične napade ali krče
What you need to know before you use Retacrit 
Kaj morate vedeti, preden boste uporabili zdravilo Retacrit
If you visit a hospital, clinic or family doctor, tell them you are having Retacrit treatment. 
Če boste obiskali bolnišnico, drugo zdravstveno ustanovo ali osebnega zdravnika, jim povejte, da se zdravite z zdravilom Retacrit.
Epoetin alfa does not induce bacterial gene mutation (Ames Test), chromosomal aberrations in mammalian cells, micronuclei in mice, or gene mutation at the HGPRT locus. 
Epoetin alfa ne inducira bakterijske genetske mutacije (Amesov test), kromosomskih aberacij v celicah sesalcev, mikronukleusov pri miših ali genskih mutacij na lokusu HGPRT.
Because Retacrit stimulates the production of red blood cells, doctors can take more blood from these people. 
Ker zdravilo Retacrit spodbuja tvorbo rdečih krvnih celic, lahko zdravniki tem osebam odvzamejo več krvi.
• For adults and children Retacrit is given as an injection either into a vein (intravenously) or a tube that goes into a vein. 
• Pri odraslih in otrocih zdravilo Retacrit dajemo v obliki injekcije bodisi v veno (intravensko) bodisi po cevki, ki vodi v veno.
Extending dose intervals may require an increase in dose. 
Pri podaljšanih odmernih intervalih bo morda treba zvišati odmerek.
If you forget to use Retacrit 
Če ste pozabili uporabiti zdravilo Retacrit
Please discuss this with your doctor. 
O tem se posvetujte s svojim zdravnikom.
Instructions on how to inject Retacrit yourself 
Navodila o tem, kako si zdravilo Retacrit injicirate sami
• Severe allergic reaction that may include: o a swollen face, lips, mouth, tongue or throat o difficulty swallowing or breathing o itchy rash (hives). 
• Hude alergijske reakcije, ki lahko vključujejo: o otekanje obraza, ustnic, ust, jezika ali žrela, o težave pri požiranju ali dihanju, o srbeč izpuščaj (koprivnica).
Side effects from an overdose of Retacrit are unlikely. 
Neželeni učinki prevelikega odmerka zdravila Retacrit so malo verjetni.
• You will usually continue Retacrit treatment for one month after the end of chemotherapy. 
• Zdravljenje z zdravilom Retacrit boste običajno nadaljevali še 1 mesec po koncu kemoterapije.
The safety and efficacy of epoetin alfa in paediatric patients receiving chemotherapy have not been established (see section 5.1). 
Varnost in učinkovitost epoetina alfa pri pediatričnih bolnikih, ki prejemajo kemoterapijo, nista bili dokazani (glejte poglavje 5.1).
No evidence exists that indicates that treatment with epoetin zeta alters the metabolism of other medicinal products. 
Ni dokazov, da bi zdravljenje z epoetinom zeta spreminjalo presnovo drugih zdravil.
Once a syringe has been removed from the refrigerator and has reached room temperature (up to 25°C) it must either be used within 3 days or disposed of. 
Ko injekcijsko brizgo vzamete iz hladilnika in se je ogrela na sobno temperaturo (do 25 °C), jo morate bodisi uporabiti v 3 dneh bodisi zavreči.
When treatment starts, Retacrit is usually injected by medical professional or a nurse. 
Ko se zdravljenje začne, vam zdravilo Retacrit običajno injicira zdravstveni delavec ali sestra.
You may still be able to use Retacrit, but discuss it with your doctor first: 
Zdravilo Retacrit lahko morda še vedno uporabljate, vendar se o tem najprej posvetujte z zdravnikom:
• Retacrit is given by injection into a vein immediately after you have donated blood for 3 weeks before your surgery. 
• Zdravilo Retacrit se daje z injekcijo v veno takoj po tem, ko ste tri tedne pred operacijo darovali kri.
If possible, iron supplementation should be initiated prior to starting epoetin zeta therapy to achieve adequate iron stores. 
Če je možno, naj se dajanje nadomestkov železa začne pred zdravljenjem z epoetinom zeta, da se dosežejo ustrezne zaloge železa.
Erythropoietin (EPO) is a glycoprotein hormone produced primarily by the kidney in response to hypoxia and is the key regulator of red blood cell (RBC) production. 
Eritropoetin (EPO) je glikoproteinski hormon, ki nastaja pretežno v ledvicah kot odziv na hipoksijo in je ključni regulator nastajanja rdečih krvničk (eritrocitov).
In 2 studies with extended interval dosing of epoetin alfa (3 times per week, once weekly, once every 2 weeks, and once every 4 weeks) some patients with longer dosing intervals did not maintain adequate haemoglobin levels and reached protocol-defined haemoglobin withdrawal criteria (0% in once weekly, 3.7% in once-every-2-weeks, and 3.3% in the once-every-4-weeks groups). 
V 2 študijah s podaljšanim intervalom odmerjanja epoetina alfa (trikrat na teden, enkrat na teden, enkrat vsaka 2 tedna in enkrat vsake 4 tedne) nekateri bolniki z daljšim intervalom odmerjanja niso ohranili ustreznih ravni hemoglobina in so dosegli v protokolu opredeljene izključitvene kriterije (0 % v skupini enkrat na teden, 3,7 % v skupini enkrat vsaka dva tedna in 3,3 % v skupini enkrat vsake 4 tedne).
The erythropoietic response observed in both treatment groups resulted in similar transfusion rates (16% in the 600 IU/kg weekly group and 20% in the 300 IU/kg daily group). 
Eritropoetski odziv, ki so ga opazili v obeh zdravljenih skupinah, se je odrazil v podobnih deležih transfuzij (16 % v skupini s 600 i.e./kg na teden in 20 % v skupini s 300 i.e./kg na dan).
• Your doctor may initiate treatment with Retacrit if your haemoglobin is 10 g/dL or less. 
• Zdravnik lahko uvede zdravljenje z zdravilom Retacrit, če znaša vaša koncentracija hemoglobina 10 g/dl ali manj.
Of a total 3 417 subjects in 25 randomised, double-blinded, placebo or standard of care controlled studies, the overall safety profile of epoetin alfa was evaluated in 2 094 anaemic subjects. 
Od skupno 3.417 preskušancev v 25 randomiziranih, dvojno slepih, s placebom ali s standardno nego nadzorovanih študijah, so splošni varnostni profil epoetina alfa ocenili pri 2.094 anemičnih preskušancih.
Some people, depending on why they need Retacrit treatment, may later learn how to inject themselves under the skin: see Instructions on how to inject Retacrit yourself. 
Nekateri se lahko pozneje naučijo, kako si zdravilo injicirajo pod kožo sami, odvisno od tega, zakaj potrebujejo zdravljenje z zdravilom Retacrit: glejte Navodila o tem, kako si zdravilo Retacrit injicirate sami.
• can't take medicines to thin the blood 
• ne smete jemati zdravil za redčenje krvi.
Your doctor will use the lowest effective dose to control the symptoms of your anemia. 
Zdravnik bo uporabil najnižji učinkoviti odmerek za nadzorovanje simptomov anemije.
The median time to target was 11 weeks and the median dose at target was 150 IU/kg/week. 
Mediani čas do ciljne vrednosti je bil 11 tednov, mediani odmerek pri ciljni vrednosti pa 150 i.e./kg/teden.
Epoetin alfa therapy reduced the risk of exposure to allogeneic blood by 50% compared to patients not receiving epoetin alfa. 
Zdravljenje z epoetinom alfa je zmanjšalo tveganje za izpostavljenost alogenski krvi za 50 % v primerjavi z bolniki, ki niso prejemali epoetina alfa.
Together, these two components comprise the needle-trap (safety) feature. 
Ti dve komponenti skupaj predstavljata varovalni nastavek Needle-Trap.
When this access (via a vein or tube) is not readily available, your doctor may decide that Retacrit should be injected under the skin (subcutaneously). 
Če ta dostop (po veni ali cevki) ni takoj na razpolago, se lahko zdravnik odloči, da bo zdravilo Retacrit injiciral pod kožo (subkutano).
Overall survival outcome in the trials could not be satisfactorily explained by differences in the incidence of thrombosis and related complications between those given recombinant human erythropoietin and those in the control group. 
Rezultata skupnega preživetja v preskušanjih niso mogli zadovoljivo razložiti z razlikami v pojavnosti tromboze in povezanih zapletov pri tistih, ki so prejemali rekombinantni humani eritropoetin, in tistih v kontrolni skupini.
A bone marrow examination should also be considered for diagnosis of PRCA. 
Pri diagnosticiranju PRCA je treba razmisliti tudi o preiskavi kostnega mozga.
What Retacrit is and what it is used for What you need to know before you use Retacrit How to use Retacrit 
Kaj je zdravilo Retacrit in za kaj ga uporabljamo Kaj morate vedeti, preden boste uporabili zdravilo Retacrit Kako uporabljati zdravilo Retacrit Možni neželeni učinki
Your healthcare professional will always record the exact product you are using. 
Zdravnik bo vedno zabeležil, katero zdravilo uporabljate.
The use of Retacrit in patients scheduled for major elective orthopaedic surgery and not participating in an autologous blood predonation programme is contraindicated in patients with severe coronary, peripheral arterial, carotid or cerebral vascular disease, including patients with recent myocardial infarction or cerebral vascular accident. 
Uporaba zdravila Retacrit pri bolnikih, ki so naročeni na večji elektivni ortopedski kirurški poseg in ne sodelujejo v programu darovanja avtologne krvi, je kontraindicirana pri bolnikih s hudo koronarno, periferno arterijsko, karotidno ali cerebrovaskularno boleznijo, vključno z bolniki, ki so nedavno preboleli miokardni infarkt ali cerebrovaskularni dogodek.
The exposure of paediatric patients with chronic renal failure on haemodialysis in clinical trials and post-marketing experience is limited. 
Izpostavljenost pediatričnih bolnikov s kronično ledvično okvaro na hemodializi v kliničnih preskušanjih in iz izkušenj v obdobju trženja je omejena.
Retacrit may be given by injection: 
Zdravilo Retacrit lahko prejemate z injekcijo:
If you use more Retacrit than you should 
Če ste uporabili večji odmerek zdravila Retacrit, kot bi smeli
Your doctor will monitor your blood pressure regularly while you are using Retacrit. 
Zdravnik bo med zdravljenjem z zdravilom Retacrit redno spremljal vaš krvni tlak.
“Instructions on how to inject Retacrit yourself” can be found at the end of the package leaflet. 
''Navodila o tem, kako si zdravilo Retacrit injicirate sami'' so na voljo na koncu navodila za uporabo.
The most frequent adverse drug reaction during treatment with epoetin alfa is a dose-dependent increase in blood pressure or aggravation of existing hypertension. 
Najpogostejši neželeni učinek, ki se pojavi med zdravljenjem z epoetinom alfa, je od odmerka odvisno zvišanje krvnega tlaka ali poslabšanje obstoječe hipertenzije.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements. 
Neuporabljeno zdravilo in injekcijske igle je treba odstraniti v skladu z lokalnimi predpisi.
Cases have also been reported in patients with hepatitis C treated with interferon and ribavirin, when ESAs are used concomitantly. 
O primerih PRCA so poročali tudi pri bolnikih s hepatitisom C, ki so se zdravili z interferonom in ribavirinom s sočasno uporabo ESA.
INTERMEDIATE CARTON (WITHOUT BLUE BOX) COMPONENT OF MULTIPACK 
VMESNA (NOTRANJA) ŠKATLA (BREZ PODATKOV ZA BLUE BOX), DEL SKUPNEGA PAKIRANJA
• Do not hold by the plunger head, plunger or needle cover. 
• Ne dotikajte se bata, glavice bata ali pokrovčka igle.
A randomized prospective trial (CHOIR) evaluated 1,432 anaemic chronic renal failure patients who were not undergoing dialysis. 
V randomiziranem, prospektivnem preskušanju (CHOIR) so ocenili 1.432 anemičnih bolnikov s kronično ledvično odpovedjo, ki se niso zdravili z dializo.
• Do not attempt to inject yourself unless you have been trained to do so by your doctor or nurse. 
• Ne poskušajte si zdravila injicirati sami, dokler vas zdravnik ali medicinska sestra ne naučita, kako to storiti.
• When the needle is pulled out of your skin, there may be a little bleeding at the injection site. 
• Ko boste iglo potegnili iz kože, se bo na mestu injiciranja morda pojavila majhna krvavitev.
In patients with chronic renal failure, maintenance haemoglobin concentration should not exceed the upper limit of the haemoglobin concentration range as recommended in section 4.2. 
Pri bolnikih s kronično ledvično okvaro vzdrževalna koncentracija hemoglobina ne sme presegati zgornje meje razpona koncentracije hemoglobina, ki je podana v poglavju 4.2.
Take special care with other products that stimulate red blood cell production: 
Bodite posebej pozorni na zdravila, ki spodbujajo nastajanje rdečih krvnih celic:
Erythropoietins exhibit a dose-related effect on haematological parameters which is independent of route of administration. 
Eritropoetin kaže od odmerka odvisen učinek na hematološke parametre, ki ni odvisen od poti uporabe.
o in adults with renal insufficiency not yet undergoing dialysis for the treatment of severe anaemia of renal origin accompanied by clinical symptoms in patients (see section 4.4). 
o pri odraslih z ledvično insuficienco, ki se jih še ne zdravi z dializo za zdravljenje hude anemije ledvičnega izvora s spremljajočimi kliničnimi znaki pri bolnikih (glejte poglavje 4.4).
In repeated dose toxicological studies in dogs and rats, but not in monkeys, epoetin alfa therapy was associated with subclinical bone marrow fibrosis. 
V toksikoloških študijah pri ponavljajočih odmerkih na psih in podganah, ne pa na opicah, je terapijo z epoetinom alfa spremljala subklinična fibroza kostnega mozga .
In those situations in which the physician determines that a patient or caregiver can safely and effectively administer Retacrit subcutaneously themselves, instruction as to the proper dosage and administration should be provided. 
Če zdravnik ugotovi, da si zdravilo Retacrit lahko varno in učinkovito daje subkutano bolnik sam ali mu ga daje skrbnik, je treba zagotoviti navodila za pravilno odmerjanje in injiciranje.
The first evidence of a response to epoetin alfa is an increase in the reticulocyte count within 10 days, followed by increases in the red cell count, haemoglobin and haematocrit, usually within 2 to 6 weeks. 
Prvi dokaz za odziv na epoetin alfa je zvečanje števila retikulocitov v 10 dneh, ki mu sledijo povečanje števila rdečih krvničk, koncentracije hemoglobina in vrednosti hematokrita, običajno v 2 do 6 tednih.
Pure Red Cell Aplasia (PRCA) 
Čista aplazija rdečih krvnih celic (PRCA - pure red cell aplasia)
The absolute bioavailability of subcutaneous injectable erythropoietin is approximately 20% in healthy subjects. 
Absolutna biorazpoložljivost eritropoetina, ki se injicira subkutano, je pri zdravih preskušancih približno 20 %.
Bone marrow fibrosis is a known complication of chronic renal failure in humans and may be related to secondary hyperparathyroidism or unknown factors. 
Fibroza kostnega mozga je pri ljudeh znan zaplet kronične ledvične odpovedi, ki je lahko povezana s sekundarnim hiperparatiroidizmom ali neznanimi dejavniki.
This medicinal product contains phenylalanine which may be harmful for people with phenylketonuria. 
To zdravilo vsebuje fenilalanin, ki lahko škoduje ljudem s fenilketonurijo.
Adults on chemotherapy 
Odrasli na kemoterapiji
As with any other injectable product, check that there are no particles in the solution or change in colour. 
Kot pri vsakem drugem zdravilu za injiciranje se prepričajte, da v raztopini ni vidnih delcev in da ni obarvana.
No evidence exists that indicates an interaction between epoetin zeta and G-CSF or GM-CSF with regard to haematological differentiation or proliferation of tumour biopsy specimens in vitro. 
Ni dokazov za medsebojno delovanje med epoetinom zeta in G-CSF ali GM-CSF glede na in vitro hematološko diferenciacijo ali proliferacijo vzorcev tumorjev, ki so bili pridobljeni z biopsijo.
The recommended total weekly dose is between 75 IU/kg and 300 IU/kg. 
Priporočeni skupni tedenski odmerek je med 75 i.e./kg in 300 i.e./kg.
Talk to your doctor if any of the following apply to you. 
Posvetujte se z zdravnikom, če za vas velja karkoli od naslednjega.
These can appear as reddish target-like macules or circular patches often with central blisters on the trunk, skin peeling, ulcers of mouth, throat, nose, genitals and eyes and can be preceded by fever and flu-like symptoms. 
Videti so lahko kot rdečkaste, tarčam podobne makule ali okrogle zaplate na trupu s pogostimi mehurčki v njihovem središču, luščenje kože, razjede v ustih, žrelu, nosu, na genitalijah in očeh, preden se pojavijo, pa lahko nastopijo zvišana telesna temperatura in gripi podobni simptomi.
Despite differences in concentration-time profiles the pharmacodynamic response (as measured by changes in percent reticulocytes, haemoglobin, and total RBCs) was similar between these regimens. 
Kljub razlikam v profilih koncentracije v odvisnosti od časa je bil farmakodinamični odziv (merjen s spremembami odstotka retikulocitov, vrednosti hemoglobina in celokupnega števila rdečih krvničk) med tema režimoma podoben.
Mean haemoglobin levels were similar for the two treatment groups throughout the postsurgical period. 
Povprečne koncentracije hemoglobina so bile podobne v obeh zdravljenih skupinah ves čas obdobja po kirurškem posegu.
In these studies, most were predialysis patients (N=44), 27 patients were on peritoneal dialysis and 2 were on haemodialysis with age ranging from 4 months to 17 years. 
V teh študijah se večina bolnikov še ni zdravila z dializo (n = 44), 27 bolnikov se je zdravilo s peritonealno dializo, 2 pa sta se zdravila s hemodializo, pri čemer je bila starost od 4 mesecev do 17 let.
In cell cultures of human bone marrow cells, epoetin alfa stimulates erythropoiesis specifically and does not affect leucopoiesis. 
Epoetin alfa v celičnih kulturah človeškega kostnega mozga specifično stimulira eritropoezo in ne vpliva na levkopoezo.
Included were 228 epoetin alfa-treated CRF subjects in 4 chronic renal failure studies (2 studies in predialysis [N = 131 exposed CRF subjects] and 2 in dialysis [N = 97 exposed CRF subjects]); 1,404 exposed cancer subjects in 16 studies of anaemia due to chemotherapy; 147 exposed subjects in 2 studies for autologous blood donation; 213 exposed subjects in 1 study in the perisurgical period, and 102 exposed subjects in 2 MDS studies. 
Vključenih je bilo 228 preskušancev s kronično ledvično odpovedjo, zdravljenih z epoetinom alfa, v 4 študijah kronične ledvične odpovedi (2 študiji pred dializo [N = 131 izpostavljenih preskušancev s kronično ledvično odpovedjo] in 2 z dializo [N = 97 izpostavljenih preskušancev s kronično ledvično odpovedjo]; 1.404 izpostavljeni preskušanci z rakom v 16 študijah z anemijo, ki je posledica kemoterapije; 147 izpostavljenih preskušancev v 2 študijah z avtolognim darovanjem krvi; 213 izpostavljenih preskušancev v 1 študiji v perioperativnem obdobju in 102 izpostavljena preskušanca v 2 študijah MDS.
Following subcutaneous injection, serum levels of erythropoietin reach a peak between 12 and 18 hours post-dose. 
Po subkutani injekciji koncentracije eritropoetina dosežejo vrh med 12 in 18 urami po odmerjanju.
In the 20-week study (n=225), no significant difference was observed in the primary efficacy endpoint, i.e. the proportion of patients who required a RBC transfusion after Day 28 (62% of epoetin alfa patients versus 69% of standard therapy patients). 
V 20-tedenski študiji (n = 225) ni bilo pomembne razlike pri primarnem opazovanem dogodku učinkovitosti, tj. deležu bolnikov, ki so potrebovali transfuzijo rdečih krvničk po 28. dnevu (62 % bolnikov, ki so se zdravili z epoetinom alfa, v primerjavi z 69 % bolnikov, ki so se zdravili s standardnim zdravljenjem).
Administration of single doses of 300 to 2 400 IU/kg subcutaneous erythropoietin resulted in a linear relationship between mean Cmax and dose and between mean AUC and dose. 
Dajanje enkratnih odmerkov 300 do 2.400 i.e./kg eritropoetina subkutano je povzročilo linearno razmerje med povprečno vrednostjo Cmax in odmerkom ter med povprečno vrednostjo AUC in odmerkom.
Additionally, cerebrovascular accidents (including cerebral infarction, cerebral haemorrhage and transient ischaemic attacks) have been reported. 
Dodatno so poročali tudi o cerebrovaskularnih dogodkih (vključno z možganskim infarktom, možgansko krvavitvijo in prehodnimi možganskimi ishemijami).
No paediatric-specific adverse reactions not mentioned previously in the table above, or any that were not consistent with the underlying disease were reported in this population. 
O neželenih učinkih, specifičnih za pediatrično populacijo, ki ne bi že bili omenjeni v zgornji preglednici ali ki ne bi bili skladni z osnovno boleznijo, pri tej populaciji niso poročali.
Chronic renal failure patients treated with epoetin zeta by the subcutaneous route should be monitored regularly for loss of efficacy, defined as absent or decreased response to epoetin zeta treatment in patients who previously responded to such therapy. 
Bolnike s kronično ledvično okvaro, ki epoetin zeta prejemajo subkutano, je treba redno spremljati glede izgube učinkovitosti, ki se kaže kot odsotnost ali zmanjšan odziv na zdravljenje z epoetinom zeta, pri tistih bolnikih, ki so se že odzivali na tako zdravljenje.
Based on information available to date, correction of anaemia with epoetin zeta in adult patients with renal insufficiency not yet undergoing dialysis does not accelerate the rate of progression of renal insufficiency. 
Na osnovi podatkov, ki so trenutno na razpolago, popravki anemije z epoetinom zeta pri odraslih bolnikih z ledvično nezadostnostjo, ki še niso na dializi, razvoja ledvične nezadostnosti ne pospešujejo.
Some patients with more extended dosing intervals (greater than once weekly) of epoetin zeta may not maintain adequate haemoglobin levels (see section 5.1) and may require an increase in epoetin zeta dose. 
Nekateri bolniki z daljšimi odmernimi intervali epoetina zeta (daljšimi kot enkrat tedensko) morda ne bodo ohranili ustreznih nivojev hemoglobina (glejte poglavje 5.1) in bodo morda potrebovali višji odmerek epoetina zeta.
Hypertensive crisis with encephalopathy and seizures, requiring the immediate attention of a physician and intensive medical care, have occurred also during epoetin zeta treatment in patients with previously normal or low blood pressure. 
Hipertenzivna kriza z encefalopatijo in epileptičnimi napadi, ki zahteva takojšnjo zdravniško pomoč in intenzivno zdravstveno oskrbo, se je pri zdravljenju z epoetinom zeta pojavila tudi pri bolnikih, ki so imeli pred tem normalen ali nizek krvni tlak.
• Let go of the plunger and allow the syringe to move up until the entire needle is guarded and locks into place. 
• Izpustite bat in pustite, da se brizga pomakne navzor, dokler celotna igla ni pokrita in se ne zaskoči.
Eighty-one percent of patients achieved the haemoglobin concentration level. 
Želeno koncentracijo hemoglobina je doseglo 81 % bolnikov.
Raised blood pressure may require treatment with medicines (or adjustment to any medicines you already take for high blood pressure). 
Zvišan krvni tlak bo morda treba zdraviti z zdravili (ali prilagoditi odmerke zdravil,