natgillin/translations-raw huggingface dataset:
In this study, 425 patients aged 16 to 70 years with uncontrolled partial-onset seizures taking stable doses of 1 or 2 marketed antiepileptic medicinal products were randomized to be converted to lacosamide monotherapy (either 400mg/day or 300mg/day in a 3:1 ratio). 
V tej študiji je bilo 425 bolnikov, starih od 16 do 70 let, z nenadzorovanimi parcialnimi napadi, ki so jemali stabilne odmerke 1 ali 2 antiepileptikov, randomizirano za prehod na samostojno zdravljenje z lakozamidom (bodisi 400 mg/dan ali 300 mg/dan, v razmerju 3:1).
• It is used to treat a certain type of epilepsy characterised by the occurrence of partial-onset seizure with or without secondary generalisation. 
• Zdravilo Lacosamide Accord se uporablja za zdravljenje določene vrste epilepsije, za katero so značilni parcialni napadi s sekundarno generalizacijo ali brez nje.
If you weigh 50 kg or more, your doctor may decide to start Lacosamide Accord treatment with a single “loading” dose of 200 mg. You would then start your ongoing maintenance dose 12 hours later. 
Če tehtate 50 kg ali več, se lahko zdravnik odloči, da začne zdravljenje z zdravilom Lacosamide Accord z enkratnim začetnim “polnilnim” odmerkom 200 mg.
Also, it is not known whether Lacosamide Accord passes into the breast milk. 
Prav tako ni znano, ali zdravilo Lacosamide Accord prehaja v materino mleko.
• fits (seizures), heart beat problems such as a slow, fast or irregular heart beat , coma or a fall in blood pressure with rapid heartbeat and sweating. 
• napadi (krči), težave s srčnim ritmom, kot je počasen, hiter ali nereden srčni utrip, koma ali padec krvnega tlaka s hitrim bitjem srca in znojenjem.
Atrioventricular block(1,2) 
Srčne bolezni atrioventrikularni blok(1,2)
Blood tests may show increased levels of liver enzymes and a type of white blood cell (eosinophilia); A widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome), and a more severe form causing skin peeling in more than 30 % of the body surface (toxic epidermal necrolysis); 
• široko razširjen izpuščaj z mehurčki in luščenjem kože še posebej okoli ust, nosu, oči in v predelu spolovil (Stevens-Johnsonov sindrom) in bolj huda oblika, ki povzroči luščenje kože na več kot 30 % telesne površine (toksična epidermalna nekroliza);
4.5 Interaction with other medicinal products and other forms of interaction Lacosamide should be used with caution in patients treated with medicinal products known to be associated with PR prolongation (including sodium channel blocking antiepileptic medicinal products) and in patients treated with class I antiarrhythmics. 
4.5 Medsebojno delovanje z drugimi zdravili in druge oblike interakcij Lakozamid je treba uporabljati previdno pri bolnikih, ki se že zdravijo z zdravili, za katera je znano, da podaljšajo interval P-R (vključno z antiepileptiki, ki zavirajo natrijeve kanalčke), ter pri bolnikih, ki se zdravijo z antiaritmiki.
Elevations of ALT to ≥ 3x ULN occurred in 0.7 % (7/935) of Lacosamide patients and 0 % (0/356) of placebo patients. 
Povišane vrednosti ALT na ≥ 3x zgornjo mejo normalnih vrednosti (ULN-upper limit of normal), so se pojavile pri 0,7 % (7/935) bolnikov, ki so jemali lakozamid, in pri 0% (0/356) bolnikov, ki so jemali placebo.
Lacosamide Accord contains soya lecithin. 
Zdravilo Lacosamide Accord vsebuje sojin lecitin.
When you take Lacosamide Accord with other antiepileptic medicines The usual starting dose of Lacosamide Accord is 50 mg twice a day. 
Ko boste vzeli zdravilo Lacosamide Accord skupaj z drugimi antiepileptiki: Običajen začetni odmerek zdravila Lacosamide Accord je 50 mg dvakrat na dan.
The most frequently reported adverse reactions (≥10 %) with lacosamide treatment were dizziness, headache, nausea and diplopia. 
Neželeni učinki, o katerih so pri zdravljenju z lakozamidom najpogosteje poročali (≥ 10 %), so bili omotica, glavobol, slabost in dvojni vid.
Lacosamide Accord is indicated as monotherapy and adjunctive therapy in the treatment of partialonset seizures with or without secondary generalisation in adults, adolescents and children from 4 years of age with epilepsy. 
Zdravilo Lacosamide Accord je indicirano za samostojno in dopolnilno zdravljenje parcialnih napadov s sekundarno generalizacijo ali brez nje pri odraslih, mladostnikih in otrocih od 4. leta starosti z epilepsijo.
Nystagmus Hypoesthesia Dysarthria Disturbance in attention 
nistagmus hipoestezija disartrija motnje pozornosti parestezija
Lacosamide Accord may make you dizzy -this could increase the risk of accidental injury or a fall. 
Zdravilo Lacosamide Accord lahko povzroča omotico, kar lahko poveča tveganje za naključne poškodbe ali padce.
The usual starting dose of Lacosamide Accord is 50 mg twice a day. 
Običajen začetni odmerek zdravila Lacosamide Accord je 50 mg dvakrat na dan.
Film-coat: Polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide (E171), lecithin (soya) and colorants* * The colorants are 
Obloga tablete: polivinilalkohol, polietilenglikol, smukec, titanov dioksid (E171), lecitin (sojin) in barvila* *Barvila so:
• Lacosamide Accord is used in adolescents and children aged 4 years and older weighing 50 kg or more and in adults. 
• Zdravilo Lacosamide Accord se uporablja pri mladostnikih in otrocih, starih 4 leta ali več, ki tehtajo 50 kg ali več, in pri odraslih.
100 mg/day or 200 mg/day 
100 mg/dan ali 200 mg/dan 100 mg/dan
The 14 x 1 or 56 x 1 tablet pack is available as perforated unit dose PVC-PVDC/Aluminium blisters sealed with an aluminium foil, all other packs are available with standard PVC-PVDC/Aluminium blisters sealed with an aluminium foil. 
Pakiranje po 14 x 1 ali 56 x 1 tableta je na voljo v perforiranih PVC-PVDC/aluminijastih pretisnih omotih za enkratni odmerek, pokritih z aluminijasto folijo.
Irritability, trouble sleeping, depression; 
razdražljivost, težave s spanjem, depresija; zaspanost, utrujenost, ali oslabelost (astenija); srbenje, izpuščaj;
Tablet core: Microcrystalline cellulose, hydroxy propyl cellulose-L, hydroxy propyl cellulose (low substituted), silica colloidal anhydrous, crospovidone and magnesium stearate. 
Jedro tablete: mikrokristalna celuloza, hidroksipropilceluloza-L, hidroksipropilceluloza (delno substituirana), koloidni brezvodni silicijev dioksid, krospovidon in magnezijev stearat.
Based on the analysis of pooled placebo-controlled clinical trials in adjunctive therapy in 1,308 patients with partial-onset seizures, a total of 61.9 % of patients randomized to lacosamide and 35.2 % of patients randomized to placebo reported at least 1 adverse reaction. 
Na osnovi analiz združenih, s placebom nadzorovanih kliničnih preskušanj pri dopolnilnem zdravljenju pri 1308 bolnikih s parcialnimi napadi, so vsaj o enem neželenem učinku poročali pri skupaj 61,9 % bolnikov, ki so randomizirano jemali lakozamid, in pri 35,2 % bolnikov, ki so randomizirano jemali placebo.
The oral bioavailability of lacosamide tablets is approximately 100%. 
Biološka uporabnost tablet lakozamida po peroralni uporabi je približno 100 %.
Lacosamide Accord is indicated as monotherapy and adjunctive therapy in the treatment of partialonset seizures with or without secondary generalisation in adolescents and children from 4 years of age weighing 50 kg or more and in adults with epilepsy. 
Zdravilo Lacosamide Accord je indicirano za samostojno in dopolnilno zdravljenje parcialnih napadov s sekundarno generalizacijo ali brez nje pri mladostnikih in otrocih od 4. leta starosti, ki tehtajo 50 kg ali več, in pri odraslih, z epilepsijo.
This is because Lacosamide Accord may make you feel dizzy or cause blurred vision. 
Razlog za to je, da lahko zdravilo Lacosamide Accord povzroča omotico ali zamegljen vid.
Adolescents and children weighing 50 kg or more and adults When you take Lacosamide Accord on its own 
Mladostniki in otroci, ki tehtajo 50 kg ali več, in odrasli Ko boste vzeli zdravilo Lacosamide Accord samostojno:
In vitro studies indicate that the enzymes CYP1A2, CYP2B6, and CYP2C9 are not induced and that CYP1A1, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP 2D6, and CYP2E1 are not inhibited by lacosamide at plasma concentrations observed in clinical trials. 
Študije in vitro kažejo, da lakozamid v plazemskih koncentracijah, izmerjenih v kliničnih preskušanjih, ne inducira encimov CYP1A2, CYP2B6 in CYP2C9 ter ne zavira encimov CYP1A1, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2D6 in CYP2E1.
Nervous system side effects such as dizziness may be higher after a single “loading” dose. 
Neželenih učinkov na centralni živčni sistem, kot je omotica, je lahko po enkratnem začetnem (polnilnem) odmerku več.
Overall the proportion of subjects with a 50% reduction in seizure frequency was 23 %, 34 %, and 40 % for placebo, lacosamide 200 mg/day and lacosamide 400 mg/day. 
V celoti je bil delež bolnikov, pri katerih se je pogostnost napadov zmanjšala za 50 %, pri placebu 23 %, pri bolnikih, ki so jemali lakozamid v odmerku 200 mg/dan, 34 % in pri bolnikih, ki so jemali lakozamid v odmerku 400 mg/dan, 40 %.
• feeling sick (nausea) or being sick (vomiting); 
• siljenje na bruhanje (navzea) ali bruhanje;
Based on the analysis of data from a non-inferiority monotherapy clinical trial comparing lacosamide to carbamazepine controlled release (CR), the most frequently reported adverse reactions (≥10 %) for lacosamide were headache and dizziness. 
Na osnovi analize podatkov dobljenih pri kliničnem preskušanju ne-inferiornega samostojnega zdravljenja, kjer so primerjali lakozamid s karbamazepinom z nadzorovanim sproščanjem, sta bila glavobol in omotica neželena učinka, o katerih so pri lakozamidu najpogosteje poročali (≥ 10 %).
On the first day of treatment the patient starts with Lacosamide Accord 50 mg tablets twice a day. 
Prvi dan zdravljenja začne bolnik z zdravilom Lacosamide Accord 50 mg tablete dvakrat na dan.
In children weighing less than 20 kg, due to an increased clearance compared to adults, a maximum dose of up to 12 mg/kg/day is recommended. 
Pri otrocih, ki tehtajo manj kot 20 kg, je zaradi povečanega očistka v primerjavi z odraslimi, priporočen največji odmerek do 12 mg/kg/dan.
In all of these controlled studies, the discontinuation rate due to adverse reactions was 12.2 % for patients randomized to lacosamide and 1.6 % for patients randomized to placebo. 
V vseh nadzorovanih študijah je zdravljenje zaradi neželenih učinkov prekinilo 12,2 % bolnikov, ki so randomizirano jemali lakozamid, in 1,6 % bolnikov, ki so randomizirano jemali placebo.
Paediatric population Adolescents and children weighing 50 kg or more 
Pediatrična populacija Mladostniki in otroci, ki tehtajo 50 kg ali več
If you forget to take Lacosamide Accord 
Če ste pozabili vzeti zdravilo Lacosamide Accord
Bradycardia(1,2) Atrial Fibrillation Atrial Flutter (1,2) 
bradikardija(1,2) atrijska fibrilacija(1,2) atrijska undulacija(1,2)
Therefore, this medicinal product should be used with caution in patients allergic to peanut or soya. 
Zdravilo Lacosamide Accord vsebuje sojin lecitin, zato je potrebna previdnost pri bolnikih, ki so alergični na arašide ali sojo.
Blister label - week 4 
PRETISNI OMOT - 4. teden
If you stop taking Lacosamide Accord 
Če ste prenehali jemati zdravilo Lacosamide Accord
Talk to your doctor before taking Lacosamide Accord if: 
Pred začetkom jemanja zdravila Lacosamide Accord se posvetujte z zdravnikom, če:
Depending on response and tolerability, the maintenance dose can be further increased at weekly intervals by 50 mg twice a day (100 mg/day), up to a maximum recommended daily dose of 300 mg twice a day (600 mg/day). 
Glede na odziv posameznega bolnika in njegovo prenašanje zdravila se lahko odmerek nadalje poveča v tedenskih intervalih za 50 mg dvakrat na dan (100 mg/dan) do največjega priporočenega dnevnega odmerka 300 mg dvakrat na dan (600 mg/dan).
Packs of 14 x 1 or 56 x 1 tablet in perforated unit dose blisters Not all pack sizes may be marketed. 
Pakiranja po 14 x 1 ali 56 x 1 tableta v perforiranih pretisnih omotih za enkratni odmerek.
Microcrystalline cellulose Hydroxy propyl cellulose-L Hydroxy propyl cellulose (low substituted) Silica, colloidal, anhydrous Crospovidone 
Jedro tablete mikrokristalna celuloza hidroksipropilceluloza-L hidroksipropilceluloza (delno substituirana) silicijev dioksid, koloidni, brezvodni krospovidon magnezijev stearat
Flatulence Dyspepsia Dry mouth Diarrhoea 
Bolezni prebavil slabost bruhanje zaprtost flatulenca dispepsija suha usta driska
Adolescents and children weighing 50 kg or more, and adults 
Mladostniki in otroci, ki tehtajo 50 kg ali več, in odrasli
Each pack of 56 film-coated tablets for a 4-week treatment schedule contains: 14 film-coated tablets of Lacosamide Accord 50 mg 14 film-coated tablets of Lacosamide Accord 100 mg 14 film-coated tablets of Lacosamide Accord 150 mg 14 film-coated tablets of Lacosamide Accord 200 mg 
Vsako pakiranje s 56 filmsko obloženimi tabletami za 4-tedensko zdravljenje vsebuje: 14 filmsko obloženih tablet zdravila Lacosamide Accord 50 mg 14 filmsko obloženih tablet zdravila Lacosamide Accord 100 mg 14 filmsko obloženih tablet zdravila Lacosamide Accord 150 mg 14 filmsko obloženih tablet zdravila Lacosamide Accord 200 mg
In interaction trials lacosamide did not significantly affect the plasma concentrations of carbamazepine and valproic acid. 
V preskušanjih medsebojnega delovanja z drugimi zdravili lakozamid ni pomembno vplival na plazemske koncentracije karbamazepina in valprojske kisline, prav tako ob uporabi karbamazepina in valprojske kisline plazemske koncentracije lakozamida niso bile spremenjene.
Depending on response and tolerability, Lacosamide Accord 150 mg tablets may be taken twice a day during the third week and Lacosamide Accord 200 mg tablets twice a day during the fourth week. 
V drugem tednu jemlje bolnik zdravilo Lacosamide Accord 100 mg tablete dvakrat na dan. Glede na odziv in prenašanje, lahko bolnik zdravilo Lacosamide Accord 150 mg tablete v tretjem tednu jemlje dvakrat na dan in v četrtem tednu zdravilo Lacosamide Accord 200 mg tablete dvakrat na dan.
• Sore throat (pharyngitis); 
• vnetje žrela (faringitis);
In paediatric patients weighing less than 50 kg with severe renal impairment (CLCR ≤ 30 ml/min) and in those with endstage renal disease, a reduction of 25 % of the maximum dose is recommended. 
Pri pediatričnih bolnikih, ki tehtajo manj kot 50 kg, s hudo ledvično okvaro (CLCR ≤ 30 ml/min) in pri tistih s končno ledvično odpovedjo je priporočeno 25-% zmanjšanje največjega odmerka.
What Lacosamide Accord looks like and contents of the pack Lacosamide Accord 50 mg are pink, oval, approximately 10.3 x 4.8 mm, coated tablets, debossed “L” on one side and “50” on other side. 
Izgled zdravila Lacosamide Accord in vsebina pakiranja Lacosamide Accord 50 mg so rožnate, ovalne obložene tablete, velike približno 10,3 x 4,8 mm z vtisnjeno oznako ‘L' na eni strani in oznako ‘50' na drugi strani.
However, cases with second- and third- degree AV Block associated with lacosamide treatment have been reported in postmarketing experience. 
Vendar pa so v obdobju trženja poročali o primerih atrioventrikularnega bloka druge in tretje stopnje, povezanih z zdravljenjem z lakozamidom.
Adolescents and children weighing 50 kg or more 
Mladostniki in otroci, ki tehtajo 50 kg ali več
Marketing Authorisation Holder Accord Healthcare S.L.U. 
IMETNIK DOVOLJENJA ZA PROMET Z ZDRAVILOM Accord Healthcare S.L.U.
MARKETING AUTHORISATION HOLDER Accord Healthcare S.L.U. 
Imetnik dovoljenja za promet z zdravilom Accord Healthcare S.L.U.
In paediatric patients weighing 50 kg or more and in adult patients with severe renal impairment (CLCR ≤30 ml/min) or with end-stage renal disease, a maximum dose of 250 mg/day is recommended and the dose titration should be performed with caution. 
Pri pediatričnih bolnikih, ki tehtajo 50 kg ali več, in pri odraslih bolnikih s hudo ledvično okvaro (CLCR ≤ 30 ml/min) ali končno ledvično odpovedjo je priporočeni največji odmerek 250 mg/dan, pri titraciji odmerka pa je potrebna previdnost.
Multiorgan hypersensitivity reactions (also known as Drug Reaction with Eosinophilia and Systemic Symptoms, DRESS) have been reported in patients treated with some antiepileptic medicinal products. 
Pri bolnikih, ki so se zdravili z nekaterimi antiepileptiki, so poročali o preobčutljivostnih reakcijah, ki so prizadele več organskih sistemov hkrati (znanih tudi kot reakcija na zdravilo z eozinofilijo in sistemskimi simptomi (DRESS).
OTHER Week 1 
DRUGI PODATKI 1. teden
One tablet of Lacosamide Accord 200 mg contains 200 mg lacosamide. 
Ena tableta zdravila Lacosamide Accord 200 mg vsebuje 200 mg lakozamida.
The AUC of lacosamide was increased by approximately 30% in mildly and moderately and 60% in severely renal impaired patients and patients with end-stage renal disease requiring haemodialysis compared to healthy subjects, whereas Cmax was unaffected. 
V primerjavi z zdravimi preiskovanci, pri katerih je bila Cmax nespremenjena, se je pri bolnikih z blago do zmerno ledvično okvaro AUC lakozamida povečala za približno 30 %, pri bolnikih s hudo ledvično okvaro in bolnikih s končno ledvično odpovedjo, ki potrebujejo dializo, pa za 60 %.
QUALITATIVE AND QUANTITATIVE COMPOSITION Lacosamide Accord 50 mg film-coated tablets One film-coated tablet contains 50 mg lacosamide. 
KAKOVOSTNA IN KOLIČINSKA SESTAVA Lacosamide Accord 50 mg filmsko obložene tablete Ena filmsko obložena tableta vsebuje 50 mg lakozamida.
Blood tests may show a severe decrease in a specific class of white blood cells (agranulocytosis); A serious skin reaction which may include a high temperature and other flu-like symptoms, a rash on the face, extended rash, swollen glands (enlarged lymph nodes). 
• resna kožna reakcija, ki lahko vključuje visoko temperaturo in druge simptome, podobne gripi, izpuščaj na obrazu, razširjen izpuščaj, otekle žleze (povečane bezgavke).
Lacosamide 600 mg/day was also shown to be effective in controlled adjunctive therapy trials, although the efficacy was similar to 400 mg/day and patients were less likely to tolerate this dose because of CNS- and gastrointestinal-related adverse reactions. 
Lakozamid v odmerku 600 mg/dan je bil v nadzorovanih raziskavah dopolnilnega zdravljenja učinkovito, vendar je bila učinkovitost podobna kot pri odmerku 400 mg/dan.
OTHER Week 4 
DRUGI PODATKI 4. teden
Based on data in adults, in paediatric patients weighing less than 50 kg with mild to moderate hepatic impairment, a reduction of 25 % of the maximum dose should be applied. 
Na podlagi podatkov, pridobljenih pri odraslih bolnikih, je treba pri pediatričnih bolnikih, ki tehtajo manj kot 50 kg, z blago do zmerno jetrno okvaro uporabiti 25-% zmanjšanje največjega odmerka.
200 mg (1 tablet Lacosamide Accord 200 mg) 
200 mg (1 tableta zdravila Lacosamide Accord 200 mg)
Lacosamide Accord 200 mg are blue, oval, approximately 16.4 x 7.6 mm, coated tablets, debossed “L” on one side and “200” on other side. 
Lacosamide Accord 200 mg so modre, ovalne obložene tablete, velike približno 16,4 x 7,6 mm z vtisnjeno oznako ‘L' na eni strani in oznako ‘200' na drugi strani.
How to take Lacosamide Accord 
Kako jemati zdravilo Lacosamide Accord
One tablet of Lacosamide Accord 50 mg contains 50 mg lacosamide. 
Ena tableta zdravila Lacosamide Accord 50 mg vsebuje 50 mg lakozamida.
50 mg tablet: Iron oxide red (E172), iron oxide black (E172), indigo carmine aluminum lake (E132) 100 mg tablet: Iron oxide yellow (E172) 
50 mg tableta: rdeči železov oksid (E172), črni železov oksid (E172), indigotin (E132) 100 mg tableta: rumeni železov oksid (E172)
The treatment initiation pack contains 56 film-coated tablets in 4 packages: the package marked ‘Week 1'contains 14 tablets of 50 mg, the package marked ‘Week 2' contains 14 tablets of 100 mg, 
Paket za začetek zdravljenja vsebuje 56 filmsko obloženih tablet v 4 pakiranjih: pakiranje z oznako ‘1.
Adolescents and children weighing 50 kg or more, and adults Monotherapy 
Mladostniki in otroci, ki tehtajo 50 kg ali več, in odrasli Samostojno zdravljenje
Lacosamide Accord contains lacosamide. 
Zdravilo Lacosamide Accord vsebuje lakozamid.
150 mg (1 tablet Lacosamide Accord 150 mg) 
150 mg (1 tableta zdravila Lacosamide Accord 150 mg)
Blue, oval, approximately 16.4 x 7.6 mm, coated tablets, debossed “L” on one side and “200” on other side. 
Modre, ovalne obložene tablete, velike približno 16,4 x 7,6 mm z vtisnjeno oznako ‘L' na eni strani in oznako ‘200' na drugi strani.
One tablet of Lacosamide Accord 150 mg contains 150 mg lacosamide. 
Ena tableta zdravila Lacosamide Accord 150 mg vsebuje 150 mg lakozamida.
Lacosamide Accord 100 mg are dark yellow, oval, approximately 13.0 x 6.0 mm, coated tablets, debossed “L” on one side and “100” on other side. 
Lacosamide Accord 100 mg so temno rumene, ovalne obložene tablete, velike približno 13,0 x 6,0 mm z vtisnjeno oznako ‘L' na eni strani in oznako ‘100' na drugi strani.
One tablet of Lacosamide Accord 100 mg contains 100 mg lacosamide. 
Ena tableta zdravila Lacosamide Accord 100 mg vsebuje 100 mg lakozamida.
150 mg tablet: Iron oxide red (E172), iron oxide black (E172), iron oxide yellow (E172) 200 mg tablet: Indigo carmine aluminum lake (E132) 
150 mg tableta: rdeči železov oksid (E172), črni železov oksid (E172), rumeni železov oksid (E172) 200 mg tableta: indigotin (E132)
Lacosamide Accord 150 mg are salmon, oval, approximately 15.0 x 6.9 mm, coated tablets, debossed “L” on one side and “150” on other side. 
Lacosamide Accord 150 mg so lososovo rožnate barve, ovalne obložene tablete, velike približno 15,0 x 6,9 mm z vtisnjeno oznako ‘L' na eni strani in oznako ‘150' na drugi strani.
100 mg (1 tablet Lacosamide Accord 100 mg) 
100 mg (1 tableta zdravila Lacosamide Accord 100 mg)
Each package has 14 tablets, corresponding to 2 tablets per day for 7 days. 
Vsako pakiranje ima 14 tablet, kar zadostuje za 7 dni jemanja po 2 tableti na dan. Vsako pakiranje vsebuje drugo jakost zdravila Lacosamide Accord, tako da boste odmerek povečevali postopno.
Your doctor may prescribe a different dose if you have problems with your kidneys or with your liver. 
Če imate težave z ledvicami ali jetri, vam bo zdravnik morda predpisal drugačen odmerek.
OTHER Week 2 
DRUGI PODATKI 2. teden
What Lacosamide Accord contains The active substance is lacosamide. 
Kaj vsebuje zdravilo Lacosamide Accord Učinkovina je lakozamid.
TREATMENT INITIATION PACK ONLY Intermediate Carton 
SAMO ZA PAKIRANJE ZA ZAČETEK ZDRAVLJENJA Notranja škatla
50 mg (1 tablet Lacosamide Accord 50 mg) 
50 mg (1 tableta zdravila Lacosamide Accord 50 mg)
Titanium dioxide (E171) Lecithin (soya) Iron oxide red (E172) Iron oxide black (E172) Iron oxide yellow (E172) 
Obloga tablete polivinilalkohol polietilenglikol smukec titanov dioksid (E171) lecitin (sojin) rdeči železov oksid (E172) črni železov oksid (E172) rumeni železov oksid (E172)
When you take Lacosamide Accord with other antiepileptic medicines Start of the treatment (the first 4 weeks) 
Ko boste vzeli zdravilo Lacosamide Accord skupaj z drugimi antiepileptiki:
Lacosamide Accord 150 mg film-coated tablets One film-coated tablet contains 150 mg lacosamide. 
Lacosamide Accord 150 mg filmsko obložene tablete Ena filmsko obložena tableta vsebuje 150 mg lakozamida.
Lacosamide Accord 200 mg film-coated tablets One film-coated tablet contains 200 mg lacosamide. 
Lacosamide Accord 200 mg filmsko obložene tablete Ena filmsko obložena tableta vsebuje 200 mg lakozamida.
• a herbal medicine used to treat mild anxiety and depression called St.John's wort. 
• zdravilo rastlinskega izvora za zdravljenje blage tesnobe, ki se imenuje šentjanževka.
Lacosamide Accord 200 mg film coated tablets: EU/1/17/1230/013-016 
Lacosamide Accord 200 mg filmsko obložene tablete EU/1/17/1230/013-016
Blood tests may show abnormal liver function, liver injury; 
Krvne preiskave lahko pokažejo povišane vrednosti jetrnih encimov in števila belih krvnih celic (eozinofilija);
Lacosamide Accord 100 mg film-coated tablets One film-coated tablet contains 100 mg lacosamide. 
Lacosamide Accord 100 mg filmsko obložene tablete Ena filmsko obložena tableta vsebuje 100 mg lakozamida.
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SN: {številka} NN: {številka}
Taking Lacosamide Accord 
Jemanje zdravila Lacosamide Accord
Lacosamide Accord 100 mg film coated tablets: EU/1/17/1230/005-008 
Lacosamide Accord 100 mg filmsko obložene tablete EU/1/17/1230/005-008