natgillin/translations-raw huggingface dataset:
Local inflammatory reactions may be accompanied, or even preceded, by flu-like systemic signs and symptoms including malaise, pyrexia, nausea, myalgias and rigors. 
Lokalne vnetne reakcije lahko spremljajo (ali jih celo prehitijo) gripi podobni sistemski znaki in simptomi, denimo, slabo počutje, pireksija, slabost, bolečine v mišicah in rigor.
Rectal disorder 
Rektalne motnje
Commonly some patients (4% or less) have experienced headache, uncommonly fevers and flu like symptoms joint and muscle pains; prolapse of the womb; pain on intercourse in females; erection difficulties; increase in sweating; feeling sick; stomach and bowel symptoms; ringing in the ears; flushing; tiredness; dizziness; migraine; pins and needles; insomnia; depression; loss of appetite; swollen glands; bacterial, viral and fungal infections (e.g. cold sores); vaginal infection including thrush; cough and colds with sore throat. 
Pogosto se je pri nekaterih bolnikih (4 % ali manj) pojavil glavobol, občasno zvišana telesna temperatura in gripi podobni simptomi in bolečine v mišicah in sklepih; prolaps maternice; bolečine ob spolnem odnosu pri ženskah; motnje erekcije; povečano potenje; slabost; simptomi v želodcu in trebuhu; zvonjenje v ušesih; rdečica; utrujenost; omotica; migrena; mravljinčenje; nespečnost; depresija; pomanjkanje apetita; otekle žleze; bakterijske, virusne in glivične okužbe (npr. herpesna okužba v ustih); okužbe v nožnici vključno s kandidazo; kašelj in prehlad z vnetim žrelom.
The efficacy of imiquimod applied 3 times per week for one or two courses of 4 weeks, separated by a 4 week treatment-free period, was studied in two double-blind vehicle controlled clinical trials. 
Učinkovitost imkvimoda trikrat tedensko za 4 tedne oz. dvakrat po 4 tedne z vmesno 4-tedensko prekinitvijo je bila raziskana v dveh dvojno slepih kliničnih preskušanjih, nadzorovanih z nosilcem.
Hardening under the skin, small open sores, a crust that forms during healing, and small bubbles under the skin may also occur. 
Lahko se pojavijo tudi otrdlina pod kožo, majhne odprte ranice, kraste in drobni mehurčki pod kožo.
Regarding the primary endpoint, histological progression, overall 13 of 242 patients (5.4%) of the imiquimod group and 26 of 237 patients (11.0%) of the diclofenac group were found to have a histological progression to in situ or invasive SCC within 3 years, a difference of -5.6% (95% CI: -10.7% to -0.7%). 
V zvezi s primarnim opazovanim dogodkom, ki je bil histološko napredovanje, so pri skupno 13 od 242 bolnikov (5,4 %) v skupini z imikvimodom in 26 od 237 bolnikov (11,0 %) v skupini z diklofenakom ugotovili histološko napredovanje v in situ ali invazivni SCC v obdobju 3 let, razlika -5,6 % (95 % IZ: -10,7 % do -0,7 %).
Pharyngo laryngeal pain 
Faringo-laringealne bolečine
In the pivotal trials with 3 times a week dosing, the most frequently reported adverse drug reactions judged to be probably or possibly related to imiquimod cream treatment were application site reactions at the wart treatment site (33.7% of imiquimod treated patients). 
V treh preskušanjih z odmerjanjem trikrat tedensko so bili najpogosteje poročani neželeni učinki, za katere je bilo presojeno, da so verjetno oz. možno povezani z zdravljenjem z imikvimod kremo, reakcije na mestu nanašanja na zdravljenem področju z bradavicami (33,7 % bolnikov, zdravljenih z imikvimodom).
If any lesions persist, treatment should be repeated for another four weeks. 
Če AK v zdravljenem področju ne izginejo je potrebno zdravljenje ponoviti za nadaljnje 4 tedne.
Based on current knowledge, treating urethral, intra-vaginal, cervical, rectal or intra-anal warts is not recommended. 
Na podlagi trenutnega znanja, zdravljenje bradavic v sečnici, nožnici, na materničnem vratu in rektalnih ter intraanalnih bradavic ni priporočljivo.
Interactions with systemic drugs would be limited by the minimal percutaneous absorption of imiquimod cream. 
Takšne reakcije s sistemskimi zdravili so omejene zaradi minimalne absorpcije imikvimod kreme skozi kožo.
100 mg of cream contains 5 mg of imiquimod. 
100 mg kreme vsebuje 5 mg imikvimoda.
Superficial basal cell carcinoma in adults: 
Površinski karcinom bazalnih celic pri odraslih bolnikih:
Each sachet contains 12.5 mg of imiquimod in 250 mg cream (5 %). 
Ena vrečka vsebuje 12,5 mg imikvimoda v 250 mg kreme (5 %).
Rare reports have been received of exacerbation of autoimmune conditions. 
Redko so poročali o poslabšanju avtoimunskih obolenj.
Due to its immunostimulating properties, imiquimod cream should be used with caution in patients who are receiving immunosuppressive medication (see section 4.4). 
Zaradi njenih imunsko-stimulativnih lastnosti pri bolnikih, ki prejemajo imunosupresivna zdravila, imikvimod kremo uporabljamo previdno (glejte poglavje 4.4).
• Superficial basal cell carcinoma. 
• Površinskega karcinoma bazalnih celic.
Aldara cream contains methyl hydroxybenzoate, propyl hydroxybenzoate, cetyl alcohol, stearyl alcohol and benzyl alcohol 
Krema Aldara vsebuje metilparahidroksibenzoat, propilparahidroksibenzoat, cetilalkohol, stearilalkohol in benzilalkohol
Men with warts under the foreskin should pull the foreskin back each day and wash underneath it. 
Moški z bradavicami pod kožico penisa morajo vsak dan kožico potegniti nazaj in kožo pod njo umiti.
• Do not use more cream than your doctor has advised. 
• Ne prekoračite priporočenega odmerka kreme.
Rarely, intense local inflammatory reactions including skin weeping or erosion can occur after only a few applications of imiquimod cream. 
Redko se lahko pojavijo burne lokalne vnetne reakcije, denimo, rosenje kože ali razjede, že po nekajkratnem nanosu kreme imikvimod.
Cream 
krema
Men with warts under the foreskin should pull the foreskin back each day and wash underneath it (see section 2 “Warnings and precautions”) 
Moški z bradavicami pod kožico penisa morajo vsak dan kožico potegniti nazaj in kožo pod njo umiti (glejte poglavje 2.
Patient reported adverse reactions from 2292 patients treated with imiquimod cream in placebo controlled and open clinical studies are presented below. 
Spodaj so prikazani podatki o reakcijah, o katerih je poročalo 2292 bolnikov, zdravljenih z imikvimod kremo v raziskavah, nadzorovanih s placebom in v odprtih kliničnih raziskavah.
After about 8 hours, wash the area where Aldara cream was applied with mild soap and water. 
Po približno 8 urah področje nanosa kreme Aldara umijte z blagim milom in vodo.
If you experience skin lesions or spots on your skin that start out as small red areas and progress to look like mini targets, possibly with symptoms such as itching, fever, overall ill feeling, achy joints, vision problems, burning, painful or itchy eyes and mouth sores, stop using Aldara cream and tell your doctor immediately. 
Če opazite na koži lezije, madeže, ki se razvijajo v majhne rdeče lise, ki se lahko še naprej povečujejo in ki jih lahko spremljajo znaki kot so srbenje, vročina, slabo počutje, bolečine v sklepih, motnje vida, pečenje, bolečine ali srbenje v očeh in izpuščaji v ustih, prenehajte uporabljati kremo Aldara in o tem obvestite svojega zdravnika.
• External genital and perianal warts (condylomata acuminata) in adults. 
• zunanjih bradavic na spolovilu in v okolici zadnjične odprtine (condylomata acuminata) pri odraslih bolnikih
Treatment with imiquimod cream can be resumed after the skin reaction has moderated. 
Zdravljenje z imikvimod kremo naj se nadaljuje, ko se reakcija umiri.
There was no evidence for serious adverse reaction caused by imiquimod in paediatric patients. 
Ni dokazov o resnih neželenih učinkih imikvimoda pri otrocih.
Imiquimod cream should be applied 3 times per week (example: Monday, Wednesday and Friday) for four weeks prior to normal sleeping hours, and left on the skin for approximately 8 hours. 
Imikvimod kremo nanašamo štiri tedne in sicer trikrat tedensko (npr. v ponedeljek, sredo in petek) pred običajnim časom spanja in jo pustimo na koži za približno 8 ur.
The most frequently reported adverse events from the trials judged probably or possibly related to imiquimod cream are application site disorders, with a frequency of 28.1%. 
Najpogosteje poročan neželen dogodek, za katerega je bilo presojeno, da so verjetno oz. možno povezani z zdravljenjem z imikvimod kremo, so bile spremembe na mestu nanašanja s pogostnostjo 28,1 %.
When applied topically, systemic overdosage with imiquimod cream is unlikely due to minimal percutaneous absorption. 
Če imikvimod krema daje topikalno, sistemsko preveliko odmerjanje ni verjetno zaradi minimalne absorpcije skozi kožo.
Application site dermatitis 
Dermatitis na mestu aplikacije
• If you are being treated for genital warts: 
● Če se zdravite zaradi genitalnih bradavic:
In 157 imiquimod-treated male patients, the combined total clearance rate was 23% as compared to 5% in 161 vehicle-treated patients (95%CI for rate difference: 3% to 36%, p<0.001). 
Pri 157 moških bolnikih, zdravljenih z imikvimodom, je bil delež bolnikov s popolno odstranitvijo bradavic 23 %, pri 161 bolnikih, zdravljenih z nosilcem, pa 5 % (95 % interval zaupanja razlike med očistkoma: 3 % do 36 %, p<0,001).
Do not use Aldara cream for more than 16 weeks in the treatment of each episode of warts. 
Kreme Aldara ne uporabljajte dlje kot 16 tednov za zdravljenje vsake ponovitve (epizode) bradavic na spolovilu ali bradavic v okolici zadnjične odprtine.
Rub gently into the skin until the cream vanishes. 
Kremo nežno vtirajte v kožo dokler ne izgine.
Imiquimod cream may weaken condoms and diaphragms, therefore concurrent use with imiquimod cream is not recommended. 
Imikvimod krema lahko oslabi kondome in diafragme, zato sočasna uporaba ni priporočljiva.
● If you are being treated for actinic keratosis 
• Če se zdravite zaradi aktinične keratoze
The cream should be rubbed into the treatment area until the cream vanishes. 
Kremo vtiramo v področje zdravljenja, dokler se ne vpije.
External genital warts: 
Zunanje genitalne bradavice:
Apart from reactions in the skin, other common effects include headache, anorexia, nausea, muscle pain, joint pain and tiredness. 
Poleg reakcij na koži so bili drugi pogosti učinki glavobol, izguba apetita, slabost, bolečine v mišicah, bolečine v sklepih in utrujenost.
Apply imiquimod cream for 6 weeks, 5 times per week (example: Monday to Friday) prior to normal sleeping hours, and leave on the skin for approximately 8 hours. 
Imikvimod kremo nanašamo petkrat tedensko (npr. od ponedeljka do petka) za 6 tednov pred običajnim časom spanja in jo pustimo na koži za približno 8 ur.
Face oedema 
Edem obraza
(3x/wk, 4 or 8 wks) N = 252 
Aktinična keratoza (3x/teden, 4 ali 8 tednov) n=252
• Actinic keratosis 
• Aktinična keratoza
The excipients methyl hydroxybenzoate (E 218) and propyl hydroxybenzoate (E 216) may cause allergic reactions (possibly delayed). 
Pomožni snovi metilhidroksibenzoat (E 218) in propilhidroksibenzoat (E 216), lahko povzročita preobčutljivostne reakcije (lahko zapoznele).
Imiquimod has not been evaluated for the treatment of basal cell carcinoma within 1 cm of the eyelids, nose, lips or hairline. 
Uporaba imikvimoda za zdravljenje karcinomov bazalnih celic, ki se nahajajo bližje kot 1 cm od očesnih vek, nosu, ustnic in lasišča, ni raziskana.
Aldara cream has no or negligible influence on the ability to drive and use machines. 
4.7 Vpliv na sposobnost vožnje in upravljanja strojev Zdravilo krema Aldara nima vpliva ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja strojev.
Imiquimod cream should be applied prior to normal sleeping hours. 
Imikvimod kremo nanašamo pred spanjem.
- If you have any further questions, please ask your doctor or your pharmacist. 
- Če imate dodatna vprašanja, se posvetujte z zdravnikom ali farmacevtom.
Do not use Aldara cream 
Ne uporabljajte kreme Aldara:
In 119 imiquimod-treated female patients, the combined total clearance rate was 60% as compared to 20% in 105 vehicle-treated patients (95% CI for rate difference: 20% to 61%, p<0.001). 
Pri 119 bolnicah, zdravljenih z imikvimodom, je bil delež bolnic s popolno odstranitvijo bradavic 60 %, pri 105 bolnicah, zdravljenih z nosilcem, pa 20 % (95 % interval zaupanja (IZ) razlike med očistkoma: 20 % do 61 %, p<0,001).
Minimal systemic absorption of imiquimod 5% cream across the skin of 58 patients with actinic keratosis was observed with 3 times per week dosing for 16 weeks. 
Pri 58 bolnikih z aktinično keratozo, ki so nanašali kremo trikrat tedensko za 16 tednov, so opazili minimalno sistemsko absorpcijo imikvimod 5 % kreme preko kože.
EU/1/98/080/001-002 
ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET Z ZDRAVILOM EU/1/98/080/001-002
Uncircumcised males treating warts under the foreskin should retract the foreskin and wash the area daily (see section 4.4). 
Neobrezani moški, ki zdravijo bradavice pod kožico penisa, morajo vsak dan kožico potegniti nazaj in prizadeto območje umiti (glejte poglavje 4.4).
Painful skin reactions at the opening of the vagina have very rarely made it difficult for some women to pass urine. 
Pri nekaterih ženskah so v zelo redkih primerih boleče kožne reakcije na področju vhoda v nožnico otežile izločanje urina.
External genital warts in adults: 
Zunanje genitalne bradavice pri odraslih bolnikih:
Uncommonly some patients experience changes at the application site (bleeding, inflammation, discharge, sensitivity, swelling, small swollen areas in the skin, pins and needles, scabbing, scarring, ulceration or a feeling of warmth or discomfort), or inflammation of the lining of the nose, stuffy nose, flu or flu-like symptoms, depression, eye irritation, swelling of the eyelid, throat pain, diarrhoea, actinic keratosis, redness, swelling of the face, ulcers, pain in extremity, fever, weakness or shivering. 
Občasno so se pri nekaterih bolnikih pojavile spremembe na mestu nanosa (krvavitev, vnetje, izcedek, občutljivost, oteklina, majhne otekline v koži, mravljinčenje, tvorba krast, zabrazgotinjenje, razjeda ali občutek toplote ali neugodja) ali vnetje sluznice nosu, zamašen nos, gripa in gripi podobni simptomi, depresija, draženje oči, oteklina očesne veke, bolečine v žrelu, driska, aktinična keratoza, rdečina, otekanje obraza, razjede, bolečine v udih, zvišana telesna temperatura, občutek slabosti in drgetanje.
Other local reactions such as induration, ulceration, scabbing, and vesicles have also been reported. 
Poročali so tudi o drugih lokalnih reakcijah, kot npr. otrdline, ulceracije, pojavu brazgotin in mehurčkov.
An interruption of dosing should be considered if intense local inflammatory reactions occur (see section 4.4) or if infection is observed at the treatment site. 
Če se pojavijo burne lokalne vnetne reakcije (glejte poglavje 4.4) ali če se na področju zdravljenja razvije okužba, je treba razmisliti o prekinitvi zdravljenja.
• Do not cover the treated area with bandages or other dressings after you have applied Aldara cream. 
• Ne pokrivajte področja zdravljenja s povoji ali obvezami po nanosu kreme Aldara.
b) Tabular Listing of adverse events: 
b) Navedba neželenih učinkov v preglednici:
Infections and infestations: Infection 
Infekcijske in parazitske bolezni: Okužba pogosti pogosti
Imiquimod cream should be applied in a thin layer and rubbed on the clean wart area until the cream vanishes. 
Imikvimod kremo nanesemo v tankem sloju na čisto področje z bradavicami in jo vtiramo dokler se krema ne vpije.
For those patients with complete clinical clearance of the treated AK field recurrence of AK lesions was evaluated. 
Pri bolnikih s popolno klinično ozdravitvijo lezij na zdravljenem AK predelu so ocenili ponovitve AK lezij.
Patient reported adverse reactions from 185 patients treated with imiquimod cream in placebo controlled phase III clinical studies for superficial basal cell carcinoma are presented below. 
Spodaj so prikazani podatki o reakcijah, o katerih je poročalo 185 bolnikov, zdravljenih z imikvimod kremo v kliničnih raziskavah faze III, nadzorovanih s placebom.
Very Commonly the treated skin may be slightly itchy. 
Zelo pogosto lahko zdravljena koža rahlo srbi.
Imiquimod should be used with caution in patients with reduced haematologic reserve (refer to section 4.8d). 
Pri bolnikih z zmanjšanimi hematološkimi vrednostmi je potrebna previdnost pri uporabi imikvimoda (glejte poglavje 4.8 d).
A single-use sachet is sufficient to cover a wart area of 20 cm 
Vrečka za enkratno uporabo zadostuje za prekritje 20 cm področja z bradavicami.
Imiquimod has the potential to exacerbate inflammatory conditions of the skin. 
Imikvimod krema lahko poslabša vnetja na koži.
Investigators of the placebo controlled clinical trials were required to evaluate protocol mandated clinical signs (skin reactions). 
Raziskovalci so morali v nadzorovanih preskušanjih z vehiklom oceniti klinične znake (lokalne reakcije na koži), ki so bili navedeni v protokolu.
Remote site skin reactions, mainly erythema (44%), were also reported in the placebo controlled trials. 
V preskušanjih nadzorovanih s placebom so poročali tudi o kožnih reakcijah na oddaljenih mestih, predvsem rdečici (44 %).
No clinical experience exists with the use of imiquimod cream in immunocompromised patients. 
Z uporabo imikvimod kreme pri imunsko kompromitiranih bolnikih kliničnih izkušenj ni.
Actinic keratosis in adults 
Aktinična keratoza pri odraslih bolnikih:
Imiquimod cream therapy should not be initiated in tissues where open sores or wounds exist until after the area has healed. 
Z imikvimod kremo se ne sme zdraviti tkiva z odprtimi ranami, dokler se le-te ne zacelijo.
How to use Aldara cream 
Kako uporabljati kremo Aldara
Imiquimod cream should be applied 3 times per week (example: Monday, Wednesday, and Friday; or Tuesday, Thursday, and Saturday) prior to normal sleeping hours, and should remain on the skin for 6 to 10 hours. 
Imikvimod kremo nanašamo trikrat tedensko (npr. v ponedeljek, sredo in petek; ali v torek, četrtek in soboto) pred spanjem.
6.1 List of excipients isostearic acid benzyl alcohol cetyl alcohol stearyl alcohol white soft paraffin polysorbate 60 sorbitan stearate glycerol methyl hydroxybenzoate (E 218) propyl hydroxybenzoate (E 216) xanthan gum purified water. 
6.1 Seznam pomožnih snovi izostearinska kislina benzilalkohol cetilalkohol stearilalkohol beli vazelin polisorbat 60 sorbitan stearat glicerol metilparahidroksibenzoat (E 218) propilparahidroksibenzoat (E 216) ksantanski gumi prečiščena voda
When clinical assessment was also included, clearance judged by this composite endpoint was noted in 75% 
Če je bilo vključeno tudi klinično vrednotenje, je bila odstranitev glede na to sestavljeno končno točko dosežena pri 75 % (139/185) vseh bolnikov.
Renal and urinary disorders: Dysuria 
Bolezni sečil: Dizurija
- The other ingredients are isostearic acid, benzyl alcohol, cetyl alcohol, stearyl alcohol, white soft paraffin, polysorbate 60, sorbitan stearate, glycerol, methyl hydroxybenzoate (E 218), propyl hydroxybenzoate (E 216), xanthan gum, purified water (see also section 2 “Aldara cream contains methyl hydroxybenzoate, propyl hydroxybenzoate, cetyl alcohol, stearyl alcohol and benzyl alcohol”). 
- Pomožne snovi so izostearinska kislina, benzilalkohol, cetilalkohol, stearilalkohol, beli vazelin, polisorbat 60, sorbitan stearat, glicerol, metilparahidroksibenzoat (E 218), propilparahidroksibenzoat (E 216), ksantanski gumi, prečiščena voda (glejte tudi poglavje 2 ''Krema Aldara vsebuje metilparahidroksibenzoat, propilparahidroksibenzoat, cetilalkohol, stearilalkohol in benzilalkohol'').
Target tumours were histologically confirmed single primary superficial basal cell carcinomas with a minimum size of 0.5 cm and a maximum diameter of 2 cm. Tumours located within 1 cm of the eyes, nose, mouth, ears or hairline were excluded. 
Ciljni tumorji so bili histološko potrjeni posamezni primarni površinski karcinomi bazalnih celic, ki so obsegali najmanj 0,5 cm2, njihov premer pa ni presegal 2 cm.
Rare cases of remote site dermatologic drug reactions, including erythema multiforme, have been reported from clinical trials. 
Pri kliničnih preskušanjih so poročali o redkih blagih primerih kožnih reakcij, vključno z multiformnim eritemom.
Five -year data from a long-term open-label uncontrolled study indicate that an estimated 77.9% [95% CI (71.9%, 83.8%)] of all the subjects who initially received treatment became clinically clear and remained clear at 60 months. 
Ocenjujejo, da so pri 77,9 % [(95 % interval zaupanja (IZ) 71,9; 83,8 %)] bolnikov, ki so prejeli zdravilo na začetku, klinični znaki bolezni izginili in se 60 mesecev niso ponovno pojavili.
LE11 5SF, United Kingdom 
Loughborough Leicestershire LE11 5SF, Velika Britanija
Do not cover the treated area with bandages or other dressings after you have applied Aldara cream. 
Ne pokrivajte področja zdravljenja s povoji ali obvezami po nanosu kreme Aldara.
● If you are being treated for basal cell carcinoma: 
● Če se zdravite zaradi karcinoma bazalnih celic:
Reductions in haemoglobin, white blood cell count, absolute neutrophils and platelets have been observed in clinical trials. 
V kliničnih preskušanjih so opazili znižanje vrednosti hemoglobina, levkocitov, absolutnih nevtrofilcev in trombocitov.
Do not apply the cream on Saturday and Sunday. 
Nanašajte kremo npr. od ponedeljka do petka, v soboto in nedeljo pa kreme ne nanašajte.
Excipients: isostearic acid, benzyl alcohol, cetyl alcohol, stearyl alcohol, white soft paraffin, polysorbate 60, sorbitan stearate, glycerol, methyl hydroxybenzoate (E 218), propyl hydroxybenzoate (E 216), xanthan gum, purified water. 
Pomožne snovi: izostearinska kislina, benzilalkohol, cetilalkohol, stearilalkohol, beli vazelin, polisorbat 60, sorbitan stearat, glicerol, metilparahidroksibenzoat (E 218), propilparahidroksibenzoat (E 216), ksantanski gumi, prečiščena voda.
Non-clinical data revealed no special hazard for humans based on conventional studies of safety pharmacology, mutagenicity and teratogenicity. 
Neklinični podatki na osnovi običajnih študij farmakološke varnosti, genotoksičnosti in vpliva na sposobnost razmnoževanja ne kažejo posebnega tveganja za človeka.
What Aldara cream contains 
Kaj vsebuje krema Aldara
• Do not apply the cream internally. 
• Krema je namenjena samo za zunanjo uporabo.
Patient reported adverse reactions from 252 patients treated with imiquimod cream in vehicle controlled phase III clinical studies for actinic keratosis are presented below. 
V preglednici so navedeni neželeni učinki, ki so se pojavili pri zdravljenju 252 bolnikov z imikvimod kremo v nadzorovanih kliničnih študijah faze III z vehiklom.
Continue treatment for four weeks. 
Kremo uporabljajte štiri tedne.
Imiquimod cream is indicated for the topical treatment of: 
Kremo z imikvimodom uporabljamo za topikalno zdravljenje:
Aldara 5% cream Imiquimod 
Aldara 5 % krema imikvimod
Topical administration of imiquimod cream resulted in no tumour enhancement at any dose, in comparison with the vehicle cream group. 
Topikalno nanašanje kreme z imikvimodom v primerjavi s skupino, ki so ji nanašali le vehikel, pri nobenem odmerku ni povzročilo rasti tumorjev.
Application site papules 
Papule na mestu aplikacije pogosti
Common effects include: pins and needles, small swollen areas in the skin, pain, burning, irritation, bleeding, redness or rash. 
Pogosti neželeni učinki so: mravljinčenje, majhne otekline v koži, bolečina, pekoč občutek, draženje, krvavitev, rdečica in izpuščaj.
Uncommonly some patients experience changes at the application site (discharge, inflammation, swelling, scabbing, skin breakdown, blisters, dermatitis) or irritability, feeling sick, dry mouth, flulike symptoms and tiredness. 
Občasno so se pri nekaterih bolnikih pojavile spremembe na mestu nanosa (izcedek, vnetje, oteklina, razvoj krast, razpokanje kože, mehurčki, dermatitis) ali draženje, občutek slabosti, izsušena usta, gripi podobni simptomi in utrujenost.
Open a new sachet each time you use the cream. 
Vsakič, ko uporabljate kremo Aldara, odprite novo vrečko.
Some systemic adverse reactions, including back pain (1.1%) and influenza-like symptoms (0.5%) were reported by imiquimod cream patients. 
Bolniki, ki so prejemali imikvimod kremo, so poročali o nekaterih sistemskih neželenih reakcijah, med drugim o bolečini v križu (1,1 %) in simptomih podobnih gripi (0,5 %).