natgillin/translations-raw huggingface dataset:
This section contains information on how to use the Prolia pre-filled syringe. 
Navodila za injiciranje zdravila Prolia v napolnjeni injekcijski brizgi To poglavje obsega informacije o uporabi napolnjene injekcijske brizge zdravila Prolia.
All women received calcium (at least 1,000 mg) and vitamin D (at least 400 IU) supplementation daily. 
Vse ženske so vsak dan dobivale dodatke kalcija (vsaj 1.000 mg) in vitamina D (vsaj 400 i.e.).
MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS PRE-FILLED SYRINGE LABEL (UNBLISTERED) 
NALEPKA ZA NAPOLNJENO INJEKCIJSKO BRIZGO (NE V PRETISNIH OMOTIH)
An absence of lactation due to inhibition of mammary gland maturation (lobulo-alveolar gland development during pregnancy) was also observed in knockout mice lacking RANK or RANKL. 
Prav tako so pri knockout miših brez RANK ali RANKL opazili odsotnost laktacije zaradi zavrtja dozorevanja mlečnih žlez (razvoj lobulo-alveolarnih žlez med brejostjo).
Women received calcium (at least 1,000 mg) and vitamin D (at least 400 IU) supplementation daily. 
Ženske so vsak dan dobivale dodatke kalcija (vsaj 1.000 mg) in vitamina D (vsaj 400 i.e.).
All men received calcium (at least 1,000 mg) and vitamin D (at least 400 IU) supplementation daily. 
Vsi moški so vsak dan dobivali dodatke kalcija (vsaj 1.000 mg) in vitamina D (vsaj 400 i.e.).
1 See section Description of selected adverse reactions 2 See section 4.4 
2 Glejte poglavje 4.4.
The mean lumbar spine BMD T-score at the end of the study was1.3 in patients treated for 10 years. 
Pri bolnicah, zdravljenih 10 let, je bila ob zaključku študije povprečna T-vrednost mineralne gostote kosti v ledvenem delu hrbtenice -1,3.
Do not shake the pre-filled syringe. 
Napolnjene injekcijske brizge NE stresajte.
DO NOT shake the pre-filled syringe. 
Napolnjene injekcijske brizge ne stresajte.
Instructions for injecting with the Prolia pre-filled syringe 
NAPOLNJENA INJEKCIJSKA BRIZGA V PRETISNEM OMOTU
Hepatic impairment 
Klinični zlom vretenc
If no improvement is noted within 48 hours, the diagnosis should be confirmed. 
Če v 48 urah ne opazite izboljšanja, je treba potrditi diagnozo.
No data to support the term “control” were provided. 
Predloženi niso bili nobeni podatki v podporo izrazu „nadzor“.
8 hours 8 hours 
8 ur 8 ur
Member State EU/EEA 
Država članica EU/EGS
In particular its activity has been demonstrated against the following micro-organism: 
Njegovo delovanje so pokazali predvsem proti naslednjim mikroorganizmom:
1 hour 1 hour 
1 ura 1 ura
Each vial is packed into a carton. 
Vsaka viala je pakirana v škatli.
The treatment appears to be intended to be preventive, which is not in line with the principles of prudent use of antibiotics. 
Zdi se, da je zdravljenje preventivno, kar ni v skladu z načeli preudarne uporabe antibiotikov.
Use only according to the benefit/risk assessment by the responsible veterinarian. 
Uporabite le skladno z oceno razmerja korist/tveganje odgovornega veterinarja.
• Avoid contact with skin and eyes. 
• Preprečite stik s kožo in očmi.
• Ensure that animals are properly restrained, including those in the vicinity. 
• Zagotovite, da so živali ustrezno obvladane, vključno z živalmi v okolici.
Occasionally, a soft diffuse swelling may occur at the injection site but this disappears within five to eight days. 
Včasih se lahko na mestu injiciranja pojavi mehka difuzna oteklina, ki pa izgine v petih do osmih dneh.
Scientific evidence suggests that macrolides act synergistically with the host immune system. 
Znanstveni dokazi kažejo, da makrolidi delujejo sinergistično z imunskim sistemom gostitelja.
Rinse any splashes from skin or eyes immediately with water. 
Vse brizge na kožo ali v oči takoj sperite z vodo.
However the bulk of the tilmicosin is excreted unchanged. 
Vendar se večina tilmikozina izloči nespremenjenega.
It is believed to affect protein synthesis. 
Menijo, da učinkuje na sintezo beljakovin.
Overall it can be concluded that data to substantiate the proposed indications in rabbits is minimally reported or lacking. 
Na splošno je mogoče zaključiti, da so podatki za utemeljitev predlaganih indikacij pri kuncih minimalni ali jih ni.
In rare cases recumbency, incoordination and convulsions have been observed. 
V redkih primerih so opazili neaktivnost, nekoordiniranost in konvulzije.
As tilmicosin persists in tissues for several days, the cardiovascular system should be closely monitored and supportive treatment provided. 
Ker tilmikozin v tkivih ostane več dni, je treba skrbno spremljati kardiovaskularni sistem in nuditi podporno zdravljenje.
The main areas of disharmony in the existing SPCs relate to: 
Glavna področja razhajanja v obstoječih povzetkih glavnih značilnosti zdravila se nanašajo na:
Minimum inhibition concentration measured in recently (2009-2012) isolated European field strains, derived from respiratory bovine disease. 
Minimalna inhibicijska koncentracija, izmerjena pri nedavno (2009-2012) izoliranih evropskih sevih s terena, ki izhajajo iz respiratorne bolezni govedi.
Do not administer to horses, donkeys, pigs, goats or primates. 
Ne uporabljajte pri konjih, oslih, prašičih, kozah ali primatih.
With regard to P. multocida it can be concluded that based on the information available for cattle this pathogen should remain in the indication. 
V zvezi z bakterijo P. multocida je mogoče zaključiti, da mora na osnovi razpoložljivih podatkov za govedo ta patogen ostati v indikaciji.
The half-life following subcutaneous injection in cattle is 2-3 days. 
Razpolovna doba po subkutanem injiciranju pri govedu je od 2 do 3 dni.
Tilmicosin in vitro microbiological data of European isolates from respiratory disease in bovines were presented for several periods (2002-2004; 2004-2006 and 2009-2013). 
In vitro mikrobiološki podatki za tilmikozin evropskih izolatov iz bolezni dihal pri govedu so bili predloženi za več obdobij (2002−2004; 2004−2006 in 2009−2013).
Wherever possible, the use of the product should be based on susceptibility testing. 
Kadar je mogoče, mora uporaba zdravila temeljiti na preiskavah za susceptibilnost.
Physicians treating patients exposed to this compound are advised to discuss clinical management with the National Poison Information Service on: ... relevant national number stated (to be completed nationally) 
Zdravniki, ki zdravijo bolnike, izpostavljene tej učinkovini, naj se posvetujejo s kliničnim vodstvom Nacionalnega organa za informacije o strupih na telefonski številki: ... navedba ustrezne nacionalne številke (izpolni država članica)
Furthermore, the safety of margin of the product is not in line with a safe use of the product in the rabbit species given the very small volume to administer. 
Nadalje meja varnosti zdravila ni v skladu z varno uporabo zdravila pri kunčjih vrstah zaradi zelo majhnega volumna za dajanje.
40 kg animals 28-50 kg animals 
40-kilogramske živali Od 28- do 50-kilogramske živali
At day 10 tilmicosin still appeared to have lower udderscores although no longer significant. 
Na 10. dan je imel tilmikozin še vedno nižje ocene vimena, čeprav niso bile več pomembne.
It has bacteriostatic action but at high concentrations it may be bactericidal. 
Deluje bakteriostatično, vendar je lahko pri velikih koncentracijah baktericiden.
Do not administer to pigs. 
Ne uporabljajte pri prašičih.
Cross resistance between tilmicosin and other macrolides and lincomycin has been observed. 
Opazili so navzkrižno rezistenco med tilmikozinom in drugimi makrolidi ter linkomicinom.
The primary cardiac effects are increased heart rate (tachycardia) and decreased contractility (negative inotrophy). 
Primarni srčni učinki so povečan srčni utrip (tahikardija) in zmanjšana kontraktilnost (negativna inotropija).
PROHIBITION OF SALE, SUPPLY AND/OR USE To be completed nationally. 
PREPOVED PRODAJE, OSKRBE IN/ALI UPORABE
These results suggest that intravenous epinephrine may be contraindicated. 
Ti rezultati kažejo, da je lahko intravenski adrenalin kontraindiciran.
Other symptoms observed were: difficulty in moving, reduced appetite and tachycardia. 
Drugi opaženi simptomi so bili: težave pri premikanju, zmanjšan tek in tahikardija.
This restriction in sheep seems difficult to “coexist” with an authorisation in rabbits whose weight is less than 5 kg (rabbits are generally slaughtered around 2.5 kg). 
Ta omejitev pri ovcah težko „soobstaja“ z dovoljenjem za kunce, ki so lažji od 5 kg (kunce se običajno zakolje pri približno 2,5 kg).
Once broached use within 28 days. 
Odprto zdravilo uporabite v 28 dneh.
Sometimes (1 in 12) a pain reaction was seen after subcutaneous injection of tilmicosin. 
Občasno (pri 1 od 12) so po subkutanem injiciranju tilmikozina zabeležili bolečinsko reakcijo.
Milk: 18 days 
Mleko: 18 dni
On 24 April 2012, the Netherlands sent a referral notification under Article 34(1) of Directive 2001/82/EC, as amended, to the CVMP/European Medicines Agency for Micotil 300 mg/ml Injectie and its associated names. 
Dne 24. aprila 2012 je Nizozemska poslala obvestilo o napotitvi v skladu s členom 34(1) Direktive 2001/82/ES, kakor je bila nazadnje spremenjena, odboru CVMP/Evropski agenciji za zdravila za zdravilo Micotil 300 mg/ml Injectie in z njim povezana imena.
Official, national and regional antimicrobial policies should be taken into account when the product is used. 
Pri uporabi zdravila je treba upoštevati uradne, nacionalne in regionalne antimikrobne politike.
The overall benefit-risk balance of the product for use in cattle and sheep was deemed positive subject to the recommended changes in the product information (see annex III). 
Celotno razmerje med tveganji in koristmi za zdravilo za uporabo pri govedu in ovcah je bilo ocenjeno kot ugodno pod pogojem, da se upoštevajo priporočene spremembe v informacijah o zdravilu (glejte Prilogo III).
A slight increase in MIC levels could be observed for Mannheimia haemolytica isolates over the last decade, most of isolates (83%) were clinically susceptible to tilmicosin. 
Rahlo povečanje ravni MIK je bilo mogoče opaziti za izolate bakterije Mannheimia haemolytica v zadnjem desetletju, od katerih je bila večina izolatov (83 %) klinično dovzetna na tilmikozin.
Milk: 36 days 
Mleko: 36 dni
Administration of dobutamine should also be considered due to its positive inotropic effects although it does not influence tachycardia. 
O uporabi dobutamina je treba razmisliti zaradi njegovih pozitivnih inotropnih učinkov, čeprav ne vpliva na tahikardijo.
TARGET SPECIES Cattle and sheep INDICATION(S) 
CILJNE ŽIVALSKE VRSTE Govedo in ovce INDIKACIJA(E)
Do not use this veterinary medicinal product after the expiry date which is stated on the label after EXP. Shelf-life after first opening the container: 28 days 
Zdravila ne smete uporabljati po datumu izteka roka uporabnosti, navedenega na nalepki po EXP. Rok uporabnosti po odprtju vsebnika: 28 dni
This led the CVMP in 2005 to limit the use of Micotil to sheep weighing more than 15 kg and to be administered by veterinary surgeons only (referral procedure under Article 35 of Directive 2001/82/EC, for Micotil 300 (EMEA/V/A/010)). 
Zaradi tega je CVMP leta 2005 omejil uporabo zdravila Micotil na ovce, težje od 15 kg, zdravilo pa lahko dajejo samo veterinarji (napotitveni postopek v skladu s členom 35 Direktive 2001/82/ES za zdravilo Micotil 300 (EMEA/V/A/010)).
An overdosage is likely to happen for such a small amount of product. 
Pri tako majhnih količinah zdravila je zelo verjetno preveliko odmerjanje.
Overall summary of the scientific evaluation of Micotil 300 mg/ml Injectie and its associated names (see annex I) 
Splošni povzetek znanstvenega vrednotenja zdravila Micotil 300 mg/ml Injectie in z njim povezanih imen (glejte Prilogo I)
Higher doses (150 mg/kg body weight) caused ataxia, lethargy and the inability to raise the head. 
Večji odmerki (150 mg/kg telesne mase) so povzročili ataksijo, letargijo in nezmožnost dvigovanja glave.
As expected, oedema developed at the site of injection. 
Kot je bilo pričakovano, se je na mestu injiciranja pojavil edem.
Therefore it is difficult to assess the efficacy of tilmicosin since no bacteriological diagnosis was conducted and both tilmicosin as well as the positive control were administered as a preventive therapeutic, five days before parturition. 
Zato je težavno oceniti učinkovitost tilmikozina, saj ni bilo izvedenih nobenih bakterioloških diagnoz, tilmikozin in pozitivne kontrole pa so bili dani preventivno terapevtsko, pet dni pred kotitvijo.
The clinical studies used naturally infected cattle with interdigital necrobacillosis without a bacteriological diagnosis. 
V klinične študije so vključili naravno okuženo govedo z interdigitalno nekrobacilozo brez bakteriološke diagnostike.
The second clinical trial which studied efficacy of tilmicosin against reproductive diseases showed no inferiority towards the positive control (penicillin combined with an aminoglycoside) however no negative controls were included. 
V drugem kliničnem preskušanju, v katerem so preučevali učinkovitost tilmikozina pri boleznih reprodukcije, niso zabeležili nobene inferiornosti v primerjavi s pozitivno kontrolo (penicilin, skupaj z aminoglikozidom), vendar ni bilo vključenih nobenih negativnih kontrol.
Treatment of interdigital necrobacillosis. 
Zdravljenje interdigitalne nekrobaciloze.
For the full list of excipients, see section 6.1. 
tilmikozin 300 mg Za celoten seznam pomožnih snovi glejte poglavje 6.1.
In milk, a concentration of tilmicosin of 1.2 µg/ml at day 3 has been measured indicating a concentration above most MIC values of the pathogens. 
Pri mleku so izmerili koncentracijo tilmikozina 1,2 µg/ml na 3. dan, kar označuje koncentracije nad večino vrednosti MIK za patogene.
Apply a cold pack (not ice directly) to the injection site. 
Na mesto injiciranja namestite hladno oblogo (ne polagajte ledu neposredno nanj).
The results show that, when administered as recommended to calves and sheep by subcutaneous injection over the dorso-lateral chest, the main parameters are: 
Rezultati kažejo, da so ob priporočeni uporabi pri teletih in ovcah s subkutanim injiciranjem v dorzolateralni predel prsnega koša glavni parametri naslednji:
Administration of intravenous calcium chloride should only be considered if there is positive confirmation of exposure to tilmicosin. 
O uporabi intravenskega kalcijevega klorida je treba razmisliti samo, če je bila izpostavitev tilmikozinu potrjena.
To avoid self-injection do not use automatic injection equipment. 
Da se izognete samoinjiciranju, ne uporabljajte opreme za samodejno injiciranje.
Bordetella bronchiseptica was not isolated in any clinical or preclinical study and no in vitro study has been performed with this bacteria. 
Bakterija Bordetella bronchiseptica ni bila izolirana v nobeni klinični ali predklinični študiji in s to bakterijo ni bila izvedena nobena študija in vitro.
PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGE Glass vial - base label (fold out label details are the same as the package leaflet) 
Steklena viala - osnovna nalepka (podrobnosti na so enake kot v navodilu za uporabo)
The Netherlands referred the issue due to divergent national decisions having been taken by the EU Member States resulting in discrepancies in the product information for Micotil 300 mg/ml Injectie and its associated names. 
Nizozemska je sprožila napotitev zaradi različnih nacionalnih odločitev, ki so jih sprejele države članice EU, kar je povzročilo odstopanja v informacijah o zdravilu za zdravilo Micotil 300 mg/ml Injectie in z njim povezana imena.
Dobutamine partially offset the negative inotropic effects induced by tilmicosin in dogs. 
Dobutamin je delno kompenziral negativne inotropne učinke, ki jih je tilmikozin povzročil pri psih.
List of the names, pharmaceutical forms, strengths of the veterinary medicinal product, animal species, route of administration, marketing authorisation holders in the Member States 
Seznam imen, farmacevtskih oblik, jakosti zdravila za uporabo v veterinarski medicini, živalskih vrst, poti uporabe in imetnikov dovoljenja za promet z zdravilom v državah članicah
• In case of self-injection SEEK IMMEDIATE MEDICAL ATTENTION and take the vial or the package leaflet with you. 
• V primeru samoinjiciranja SE TAKOJ POSVETUJTE Z ZDRAVNIKOM in mu pokažite navodila za uporabo ali vialo.
Micotil 300 Injectie and its associated names are veterinary medicinal products authorised for use in the target species cattle, sheep and rabbits for treatment of various infections caused by microorganisms susceptible to tilmicosin. 
Zdravilo Micotil 300 Injectie in z njim povezana imena so zdravila za uporabo v veterinarski medicini, ki so odobrena za uporabo pri ciljnih vrstah goveda, ovc in kuncev za zdravljenje različnih okužb, ki jih povzročajo mikroorganizmi, dovzetni na tilmikozin.
Do not administer to horses and donkeys. 
Ne uporabljajte pri konjih in oslih.
Mannheimia, Pasteurella, Actinomyces (Corynebacterium), Fusobacterium, Dichelobacter, Staphylococcus, and Mycoplasma organisms of bovine and ovine origin. 
Mannheimia, Pasteurella, Actinomyces (Corynebacterium), Fusobacterium, Dichelobacter, Staphylococcus ter organizmom Mycoplasma govejega in ovčjega izvora.
Staphylococcus aureus was not isolated in any preclinical study or clinical trial. 
Bakterija Staphylococcus aureus ni bila izolirana v nobeni predklinični študiji ali v kliničnem preskušanju.
The use of the product should be based on susceptibility tests. 
Uporaba tega zdravila mora temeljiti na preiskavah susceptibilnosti.
• This product should only be administered by a veterinary surgeon. 
• To zdravilo lahko daje samo veterinarski kirurg.
• Do not use automatic injection equipment. 
• Ne uporabljajte opreme za samodejno injiciranje.
Numerous field studies using naturally infected calves of various ages with pneumonia, conducted over 20 years ago, indicated that tilmicosin is not inferior towards other positive controls, being long acting antibiotics or combinations of two antibiotics. 
Številne študije na terenu, v katere je bilo vključeno naravno okuženo govedo različnih starosti s pljučnico in so bile izvedene pred več kot 20 leti, nakazujejo, da tilmikozin ni slabši do drugih pozitivnih kontrol, na primer dolgodelujočih antibiotikov ali kombinacij dveh antibiotikov.
Biotransformation: Several metabolites are formed, the predominant one being identified as T1 (Ndemethyl tilmicosin). 
Biotransformacija: Tvorili so se mnogi presnovki, od katerih je bil glavni T1 (N-demetiltilmikozin).
MIC measured in these isolates did not show an increase in MIC levels for Pasteurella multocida (97% of the isolates were susceptible to tilmicosin), therefore from the data provided no trend in resistance increase could be observed for one of the major pathogens for respiratory diseases in cattle. 
Vrednosti MIK, izmerjene v teh izolatih, niso pokazale povišanja ravni MIK za bakterijo Pasteurella multocida (97 % izolatov je bilo dovzetnih na tilmikozin), zato iz predloženih podatkov ni mogoče opaziti nobenega trenda povečanja odpornosti za enega najpomembnejših patogenov za bolezni dihal pri govedu.
Additional operator safety warnings: 
Dodatna varnostna opozorila za uporabnika:
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with national requirements. 
Vsako neporabljeno zdravilo za uporabo v veterinarski medicini ali odpadne snovi, ki nastanejo iz teh zdravil, je treba odstraniti skladno z lokalnimi predpisi.
Macrolides appear to enhance phagocyte killing of bacteria. 
Videti je, da makrolidi okrepijo pobijanje bakterij, ki ga povzročajo fagociti.
The MIC90 data from recently isolated European strains should be included in SPC section 5.1 Pharmacodynamic properties. 
Podatke MIK90 iz nedavno izoliranih evropskih sevov je treba vključiti v poglavje 5.1 Farmakodinamične lastnosti povzetka glavnih značilnosti zdravila.
Tilmicosin is a mainly bactericidal semi-synthetic antibiotic of the macrolide group. 
Tilmikozin je večinoma baktericidni polsintetični antibiotik iz skupine makrolidov.
Cattle and sheep 
Govedo in ovce
Benefit-Risk assessment 
Ocena razmerja med tveganji in koristmi
Cardiovascular toxicity may be due to calcium channel blockade. 
Kardiovaskularna toksičnost je lahko posledica blokade kalcijevih kanalčkov.
Avoid introduction of contamination into vial during use. 
Med uporabo preprečite kontaminacijo v viali.
The CVMP concluded that, due to limited availability of alternative veterinary medicinal products for this indication and in the absence of reports on suspected lack of efficacy, the indication “for treatment of ovine mastitis associated with Staphylococcus aureus and Mycoplasma agalactiae” should be maintained, but in a modified manner to better reflect the study results, to “treatment of acute ovine mastitis associated with Staphylococcus aureus and Mycoplasma agalactiae”. 
CVMP je zaključil, da je treba zaradi omejene razpoložljivosti alternativnih zdravil za uporabo v veterinarski medicini za to indikacijo in zaradi odsotnosti poročil o domnevnem pomanjkanju učinkovitosti indikacijo „za zdravljenje mastitisa pri ovcah, povezanega z bakterijama Staphylococcus aureus in Mycoplasma agalactiae“ ohraniti, vendar spremeniti tako, da bolje odraža rezultate študije, in sicer „za zdravljenje akutnega mastitisa pri ovcah, povezanega z bakterijama Staphylococcus aureus in Mycoplasma agalactiae“.
The safety of the veterinary medicinal product has not been established during pregnancy. 
Varnost zdravila v obdobju brejosti ni bila ugotovljena.
Veterinary medicinal product must not be disposed of via waste water or the drainage systems. 
Zdravila za uporabo v veterinarski medicini ne smete zavreči v odpadne vode ali drenažne sisteme.
• May cause sensitisation by skin contact. 
• Ob stiku s kožo lahko povzroči senzibilizacijo.
In pigs, intramuscular injection of 10 mg tilmicosin/kg body weight caused increased respiration, emesis and convulsions; 20 mg/kg body weight resulted in mortality in 3 of 4 pigs, and 30 mg/kg body weight caused the death of all 4 pigs tested. 
Pri prašičih je intramuskularno injiciranje 10 mg tilmikozina/kg telesne mase povzročilo pospešeno dihanje, emezo in konvulzije; odmerek 20 mg/kg telesne mase je povzročil smrt 3 od 4 prašičev, odmerek 30 mg/kg telesne mase pa smrt vseh 4 testiranih prašičev.
THE WORDS “FOR ANIMAL TREATMENT ONLY” AND CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE, IF APPLICABLE For animal treatment only. 
BESEDILO »SAMO ZA ŽIVALI« IN POGOJI ALI OMEJITVE GLEDE OSKRBE IN
In sheep single injections (approximately 30 mg/kg body weight) may cause a slight increase of the rate of respiration. 
Pri ovcah lahko enkratno injiciranje (v odmerku približno 30 mg/kg telesne mase) povzroči rahlo povečanje frekvence dihanja.
Elimination: Following subcutaneous injection, tilmicosin is excreted mainly via the bile into the faeces, but a small proportion is excreted via the urine. 
Izločanje: Po subkutanem injiciranju se tilmikozin izloča zlasti prek žolča z blatom, majhen delež pa se izloči z urinom.
Animal species Route of administration 
Živalska vrsta Pot uporabe
The Netherlands 
Nizozemska NIZOZEMSKA
Intravenous injection in cattle and sheep has been fatal. 
Intravensko injiciranje pri govedu in ovcah je povzročilo smrt.
Since no dose-finding studies in rabbits were provided it cannot be concluded from the data available that Pasteurellosis can be treated with the recommended tilmicosin dosage of 10 mg/kg body weight. 
Ker ni bilo predloženih nobenih študij za določitev odmerka pri kuncih, iz razpoložljivih podatkov ni mogoče zaključiti, da je mogoče bakterijo Pasteurellosis zdraviti s priporočenim odmerkom tilmikozina 10 mg/kg telesne mase.
When a group of animals has to be treated, leave the needle in the vial to remove the subsequent doses. 
Če zdravite skupino živali, pustite iglo v viali, da lahko izvlečete naslednje odmerke.
Pre-clinical data and an isolated clinical report suggest that calcium chloride infusion may help to reverse tilmicosin induced changes in blood pressure and heart rate in humans. 
Predklinični podatki in eno klinično poročilo kažejo, da lahko infundiranje kalcijevega klorida pomaga odpraviti spremembe krvnega tlaka in srčnega utripa, ki jih pri človeku povzroči tilmikozin.