natgillin/translations-raw huggingface dataset:
Cholestagel as monotherapy is indicated as adjunctive therapy to diet for reduction of elevated total-cholesterol and LDL-C in adult patients with primary hypercholesterolaemia, in whom a statin is considered inappropriate or is not well-tolerated. 
Zdravilo Cholestagel kot monoterapija je indicirano kot dodatno zdravljenje ob dieti za zniževanje zvišanega celokupnega holesterola in holesterola LDL (LDL-C) pri odraslih bolnikih s primarno hiperholesterolemijo, za katere se smatra, da statin ni ustrezen ali ga slabo prenašajo.
In an interaction study in healthy volunteers, co-administration of Cholestagel and ciclosporin significantly reduced the AUC0-inf and Cmax of ciclosporin by 34% by 44%, respectively. 
V klinični raziskavi medsebojnega delovanja pri zdravih prostovoljcih je sočasno jemanje zdravila Cholestagel in ciklosporina znatno znižalo vrednosti AUC0-inf ciklosporina za 34% in vrednosti Cmax ciklosporina za 44%.
The most frequently occurring adverse reactions are flatulence and constipation, found within the gastrointestinal disorders system organ class. 
Neželena učinka, o katerih so poročali najpogosteje sta flatulenca in obstipacija, ki po klasifikaciji spadata v organski sistem bolezni prebavil.
In a 6-month dose-response study in patients with primary hypercholesterolaemia receiving 3.8 or 4.5 g Cholestagel daily, a 15 to 18% decrease in LDL-C levels was observed, which was evident within 2 weeks of administration. 
V šestmesečni študiji odzivnosti na odmerke pri bolnikih s primarno hiperholesterolemijo, ki so dnevno prejemali 3,8 ali 4,5 g zdravila Cholestagel, so v prvih dveh tednih opazili od 15 do 18 % znižanje koncentracije holesterola LDL.
In addition, Total-C decreased 7 to 10%, HDL-C increased 3% and triglycerides increased 9 to 10%. 
10 %, koncentracija holesterola HDL se je zvišala za 3 %, koncentracija trigliceridov pa za 9 do 10 %.
Should overdosage occur, however, the chief potential harm would be obstruction of the gastrointestinal tract. 
Ob morebitnem prevelikem odmerjanju bi bila osnovna potencialna težava obstrukcija prebavil.
QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains 625 mg colesevelam (as hydrochloride). 
KAKOVOSTNA IN KOLIČINSKA SESTAVA Vsaka tableta vsebuje 625 mg holesevelama (v obliki holesevelamijevega klorida).
High density polyethylene bottles with a polypropylene cap without outer carton. 
Plastenke iz polietilena visoke gostote s pokrovom iz polipropilena brez zunanje ovojnine.
Antidiabetic agents 
Antidiabetična zdravila
Your liver uses cholesterol from your blood to do this, which lowers the level of cholesterol in your blood. 
Za to jetra uporabijo holesterol iz krvi, kar znižuje njegovo koncentracijo v krvi.
• Anti-epileptic medicines (medicines, such as phenytoin, used to treat epilepsy). 
• antiepileptična zdravila (zdravila za zdravljenje epilepsije, kot je fenitoin),
Ursodeoxycholic acid 
Ursodeoksiholna kislina
The fenofibrate plus Cholestagel group (64 patients) demonstrated a 10% reduction on LDL-C levels versus 2% increase for the fenofibrate group 
V skupini, ki je jemala fenofibrat in zdravilo Cholestagel (64 bolnikov), je prišlo do 10 % znižanja ravni holesterola LDL v primerjavi z 2 % zvišanjem v skupini, ki je jemala samo fenofibrat (65 bolnikov).
Cholestagel tablets are off-white, capsule-shaped film-coated tablets and imprinted with ‘C625' on one side. 
Tablete Cholestagel so sivobele filmsko obložene tablete v obliki kapsul z napisom "C625" na eni strani.
Cholestagel co-administered with a 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitor (statin) is indicated as adjunctive therapy to diet to provide an additive reduction in low-density lipoprotein cholesterol (LDL-C) levels in adult patients with primary hypercholesterolaemia who are not adequately controlled with a statin alone. 
Zdravilo Cholestagel, uporabljeno sočasno z inhibitorjem 3-hidroksi-3-metilglutaril-koencim A (HMG-CoA) reduktazo (statinom), je indicirano kot dodatno zdravljenje ob dieti za dodatno zniževanje koncentracije holesterola z lipoproteini nizke gostote (LDL-C) pri odraslih bolnikih s primarno hiperholesterolemijo, pri katerih zgolj statin ni dovolj učinkovit.
Microcrystalline cellulose (E460) Silica colloidal anhydrous Magnesium stearate Purified water 
Jedro tablete: mikrokristalna celuloza (E460) brezvodni koloidni silicijev dioksid magnezijev stearat prečiščena voda
The combination of ezetimibe 10 mg and Cholestagel 3.8 g daily therapy in the absence of a statin resulted in a significant combined effect for LDL-C lowering by 32% demonstrating an additional effect of 11% LDL-C lowering with Cholestagel and ezetimibe compared to ezetimibe alone. 
S kombinacijo 10 mg ezetimiba in 3,8 g zdravila Cholestagel dnevno brez statina so dosegli statistično pomemben kombiniran učinek znižanja koncentracije holesterola LDL za 32 %, kar pomeni, da je kombinacija zdravila Cholestagel in ezetimiba dodatno znižala koncentracijo holesterola LDL za 11 % v primerjavi z ezetimibom samim.
If you stop taking Cholestagel Your cholesterol may increase to the level it was before treatment was started. 
Koncentracija holesterola se lahko dvigne do koncentracije, kakršno ste imeli pred začetkom zdravljenja.
Do not take Cholestagel: - if you are allergic to colesevelam or to any of the other ingredients of this medicine (listed in section 6) - if you have a blockage in your intestines or bile ducts (tubes that carry bile) 
Kaj morate vedeti, preden boste vzeli zdravilo Cholestagel Ne jemljite zdravila Cholestagel - če ste alergični na holesevelam ali katero koli sestavino tega zdravila (navedeno v poglavju 6), - če imate zaporo v črevesju ali žolčevodih (vodi za izločanje žolča).
This prevents your body from recycling the bile acids from your intestines in the usual way. 
To telesu preprečuje običajno ponovno uporabo žolčnih kislin iz črevesja.
In an interaction study in healthy volunteers, Cholestagel reduced the Cmax of norethindrone as well as the AUC and Cmax of ethinylestradiol when administered simultaneously with the oral contraceptive pill. 
V študiji o medsebojnem delovanju pri zdravih prostovoljcih je zdravilo Cholestagel znižalo vrednosti Cmax noretindrona ter vrednosti AUC in Cmax etinilestradiola ob sočasnem jemanju s peroralno kontracepcijsko tabletko.
How to take Cholestagel 
Kako jemati zdravilo Cholestagel
Cholestagel is not absorbed from the gastrointestinal tract. 
Cholestagel se ne absorbira iz prebavil.
The LDL-C lowering mechanism of bile acid sequestrants has been previously established as follows: As the bile acid pool becomes depleted, the hepatic enzyme, cholesterol 7--hydroxylase, is upregulated, which increases the conversion of cholesterol to bile acids. 
Mehanizem nižanja koncentracije holesterola LDL absorbentov žolčnih kislin deluje na naslednji način: Ko začne zmanjkovati žolčnih kislin, se poveča delovanje jetrnega encima holesterol 7--hidroksilaze, kar poveča pretvorbo holesterola v žolčne kisline.
MARKETING AUTHORISATION HOLDER Genzyme Europe B.V., Paasheuvelweg 25, 1105 BP Amsterdam, the Netherlands. 
IMETNIK DOVOLJENJA ZA PROMET Z ZDRAVILOM Genzyme Europe B.V., Paasheuvelweg 25, 1105 BP Amsterdam, Nizozemska.
- Cholestagel may be prescribed on its own in addition to a diet low in fat and cholesterol when treatment with a statin (a class of cholesterol-lowering medicines that work in the liver) is inappropriate or not well tolerated. 
- Zdravilo Cholestagel se lahko predpiše samostojno, poleg diete z nizko vsebnostjo maščob in holesterola, kadar zdravljenje s statinom (vrsta zdravil za zniževanje koncentracije holesterola, ki delujejo v jetrih) ni ustrezno ali če ga bolniki ne prenašajo dobro.
Cholestagel can also be used in combination with ezetimibe, with or without a statin, in adult patients with primary hypercholesterolaemia, including patients with familial hypercholesterolaemia (see section 5.1). 
Zdravilo Cholestagel se pri odraslih bolnikih s primarno hiperholesterolemijo, vključno z bolniki z družinsko hiperholesterolemijo, lahko uporabi tudi v kombinaciji z ezetimibom s statinom ali brez njega (glejte poglavje 5.1).
It is important that you take olmesartan at least 4 hours before you take Cholestagel. 
Pomembno je, da vzamete olmesartan vsaj 4 ure pred zaužitjem zdravila Cholestagel.
It is important that you take glimepiride and glipizide at least 4 hours before you take Cholestagel. 
Pomembno je, da vzamete glimepirid in glipizid vsaj 4 ure pred zaužitjem zdravila Cholestagel.
Cholestagel tablets should be taken orally with a meal and liquid. 
Tablete Cholestagel je treba jemati peroralno s tekočino in ob obroku.
Multi-centre, randomised, double-blind, placebo-controlled studies in 487 patients demonstrated an additive reduction of 8 to 16% in LDL-C when 2.3 to 3.8 g Cholestagel and a statin (atorvastatin, lovastatin or simvastatin) were administered at the same time. 
Multicentrične, randomizirane, dvojno slepe s placebom kontrolirane študije na 487 bolnikih so pri sočasni uporabi 2,3 do 3,8 g zdravila Cholestagel in statina (atorvastatina, lovastatina ali simvastatina) pokazale dodatno znižanje koncentracije holesterola LDL za 8 do 16 %.
Driving and using machines Your ability to drive or operate machines is not affected by taking Cholestagel tablets. 
Vpliv na sposobnost upravljanja vozil in strojev Jemanje tablet Cholestagel ne vpliva na vašo sposobnost upravljanja vozil in strojev.
There is no need for dose adjustment when Cholestagel is administered to elderly patients. 
Starejši bolniki Pri uporabi zdravila Cholestagel pri starejših bolnikih ni potrebno prilagoditi odmerka.
Always take Cholestagel exactly as your doctor or pharmacist has told you. 
Pri uporabi zdravila Cholestagel natančno upoštevajte navodila svojega zdravnika ali farmacevta.
Cholestagel works in your intestinal system by binding bile acids produced by your liver and carrying the bile acids out of your body with your faeces. 
Zdravilo Cholestagel deluje v prebavilih tako, da veže žolčne kisline, ki jih proizvajajo jetra, ter jih izloči z blatom.
When a drug interaction cannot be excluded with a concomitant medicinal product for which minor variations in the therapeutic level would be clinically important, or where no clinical data are available on co-administration, Cholestagel should be administered at least four hours before or at least four hours after the concomitant medication in order to minimize the risk of reduced absorption of the concomitant medication (see section 4.5). 
Kadar ne morete izključiti medsebojnega delovanja s sočasno uporabljenim zdravilom, pri katerem bi lahko bile manjše spremembe pri zdravljenju klinično pomembne ali kadar ni kliničnih podatkov o sočasni uporabi, je potrebno zdravilo Cholestagel vzeti vsaj štiri ure pred ali vsaj štiri ure po sočasno uporabljenem zdravilu, da bi zmanjšali tveganje zmanjšane absorpcije sočasno uporabljenega zdravila (glejte poglavje 4.5).
- Cholestagel may be used together with a statin and the diet low in fat and cholesterol when patients are not appropriately controlled by the statin on its own. 
- Zdravilo Cholestagel se lahko uporablja skupaj s statini in dieto z nizko vsebnostjo maščob in holesterola, kadar zdravljenje samo s statini ne zadostuje.
Cholestagel resulted in a statistically significant LDL-C reduction of 11% and 11% at 6 and 12 weeks vs an increase of 7% and 1% in the placebo group; mean baseline levels were 3.75 mmol/L and 3.86 mmol/L, respectively. 
Zdravilo Cholestagel je povzročilo statistično pomembno znižanje koncentracije holesterola LDL za 11 % po 6 tednih in 11 % po 12 tednih iz povprečne izhodiščne koncentracije 3,75 mmol/L, v placebo skupini pa se je koncentracija holesterola LDL po 6 tednih zvišala za 7 %, po 12 tednih pa za 1 % iz povprečne izhodiščne koncentracije 3,86 mmol/L.
Marketing authorisation holder Genzyme Europe B.V., Paasheuvelweg 25, 1105 BP Amsterdam, the Netherlands 
Imetnik dovoljenja za promet z zdravilom Genzyme Europe B.V., Paasheuvelweg 25, 1105 BP Amsterdam, Nizozemska
Co-administration of colesevelam and glipizide decreases the exposure of glipizide. 
Sočasno jemanje holesevelama in glipizida zmanjša izpostavljenost glipizidu.
In an interaction study in healthy volunteers, Cholestagel reduced the AUC and Cmax of levothyroxine when administered either concomitantly or after 1 hour. 
V študiji o medsebojnem delovanju pri zdravih prostovoljcih je zdravilo Cholestagel znižalo vrednosti AUC in Cmax levotiroksina tako ob sočasnem jemanju kot po 1 uri.
The location of such potential obstruction, the degree of obstruction and the presence or absence of normal gut motility would determine treatment. 
Zdravljenje bi bilo odvisno od mesta in stopnje obstrukcije ter normalne ali nenormalne gibljivosti prebavil.
Anticoagulant therapy should be monitored closely in patients receiving warfarin or similar agents, since bile acid sequestrants, like Cholestagel, have been shown to reduce absorption of vitamin K and therefore interfere with warfarin's anticoagulant effect (see also section 4.5). 
Pri bolnikih, ki prejemajo varfarin ali podobne učinkovine, morate zdravljenje z antikoagulanti pozorno spremljati, kajti adsorbenti žolčnih kislin, kot je zdravilo Cholestagel, zmanjšujejo absorpcijo vitamina K in tako ovirajo antikoagulantni učinek varfarina (glejte tudi poglavje 4.5).
For all patients, Cholestagel resulted in a statistically significant LDL-C reduction of 11% at 3.8 g/day and 4% at 1.9 g/day, versus a 3% increase in the placebo group. 
Pri vseh bolnikih se je po zdravljenju z zdravilom Cholestagel statistično pomembno znižala koncentracija holesterola LDL, in sicer za 11 % v skupini, ki je prejemala odmerek 3,8 g/dan, in za 4 % v skupini, ki je prejemala odmerek 1,9 g/dan, v placebo skupini pa se je koncentracija zvišala za 3 %.
Your doctor may tell you to take the Cholestagel dose either once a day or twice a day; in either case Cholestagel should be taken with a meal. 
Zdravnik vam bo morda dejal, da vzamete odmerek zdravila Cholestagel bodisi enkrat ali dvakrat dnevno.
What Cholestagel contains 
Kaj vsebuje zdravilo Cholestagel
Cholestagel 625 mg film-coated tablets Colesevelam 
Cholestagel 625 mg filmsko obložene tablete holesevelam
Patients starting on ciclosporin already taking Cholestagel should have their ciclosporin blood concentrations monitored as normal and their dose adjusted as normal. 
Bolniki, ki že jemljejo zdravilo Cholestagel in bodo hkrati začeli jemati ciklosporin, morajo imeti kontrolne izmerjene vrednosti ciklosporina v krvi normalne in odmerek ciklosporina prilagojen normalni vrednosti.
As noted in general, when a drug interaction cannot be excluded with a concomitant medicinal product, Cholestagel should be administered at least four hours before or at least four hours after the concomitant medication to minimise the risk of reduced absorption of the concomitant medication. 
Na splošno velja, da je potrebno v primeru, kadar ne morete izključiti medsebojnega delovanja s sočasno uporabljenim zdravilom, zdravilo Cholestagel vzeti vsaj štiri ure pred ali vsaj štiri ure po sočasno uporabljenem zdravilu, da bi zmanjšali tveganje zmanjšane absorpcije sočasno uporabljenega zdravila.
Cholestagel contains the active substance colesevelam (as hydrochloride). 
Zdravilo Cholestagel vsebuje učinkovino holesevelam (v obliki holesevelamijevega klorida).
Cholestagel has not been compared directly to other bile acid sequestrants in clinical trials. 
V kliničnih preskušanjih niso neposredno primerjali zdravila Cholestagel z drugimi adsorbenti žolčnih kislin.
The maximum recommended dose is 6 tablets per day taken as 3 tablets twice per day with meals or 6 tablets taken once per day with a meal. 
Najvišji priporočeni odmerek je 6 tablet dnevno, ki se vzamejo kot 3 tablete dvakrat dnevno, ob obrokih, ali 6 tablet enkrat dnevno, ob obroku.
- The active substance is colesevelam (as hydrochloride). 
- Zdravilna učinkovina je holesevelam (v obliki holesevelamijevega klorida).
For statin-naïve patients on monotherapy, Cholestagel resulted in a statistically significant LDL-C reduction of 12% at 3.8 g/day and 7% at 1.9 g/day, versus a 1% reduction in the placebo group (see section 4.2). 
Pri bolnikih, ki se še niso zdravili s statini v obliki monoterapije, se je po zdravljenju z zdravilom Cholestagel statistično pomembno znižala koncentracija holesterola LDL, in sicer za 12 % v skupini, ki je prejemala odmerek 3,8 g/dan, in za 7 % v skupini, ki je prejemala odmerek 1,9 g/dan, v placebo skupini pa se je koncentracija znižala za 1 % (glejte poglavje 4.2).
Co-administration of colesevelam and olmesartan decreases the exposure of olmesartan. 
Sočasno jemanje holesevelama in olmesartana zmanjša izpostavljenost olmesartanu.
The background incidence of flatulence and diarrhoea were higher in patients receiving placebo in the same controlled clinical studies. 
V istih nadziranih kliničnih študijah so opazili večjo pogostost pojavljanja flatulence in diareje pri bolnikih, ki so prejemali placebo.
Anticoagulant therapy should be monitored closely in patients receiving warfarin or similar agents, since bile acid sequestrants, like Cholestagel, have been shown to reduce absorption of vitamin K and therefore interfere with warfarin's anticoagulant effect. 
Pri bolnikih, ki prejemajo varfarin ali podobna zdravila, morate zdravljenje z antikoagulanti pozorno spremljati, kajti adsorbenti žolčnih kislin, kot je zdravilo Cholestagel, zmanjšujejo absorpcijo vitamina K in tako ovirajo antikoagulatni učinek varfarina.
Patients starting on Cholestagel already taking ciclosporin should have their blood concentrations monitored prior to combination therapy and frequently monitored immediately starting co-therapy with the ciclosporin dose adjusted accordingly. 
Pri bolnikih, ki že jemljejo ciklosporin in bodo hkrati začeli jemati tudi zdravilo Cholestagel, se morajo izvajati kontrolne meritve vrednosti v krvi pred kombiniranim zdravljenjem in nato pogosto takoj po začetku kombiniranega zdravljenja s ciklosporinom; odmerek ciklosporina mora biti ustrezno prilagojen.
Therefore when a drug interaction cannot be excluded with a concomitant medicinal product for which minor variations in the therapeutic level would be clinically important, Cholestagel should be administered at least four hours before or at least four hours after the concomitant medication to minimize the risk of reduced absorption of the concomitant medication. 
Kadar ne morete izključiti medsebojnega delovanja s sočasno uporabljenim zdravilom, pri katerem bi lahko bile manjše spremembe pri zdravljenju klinično pomembne, je potrebno zdravilo Cholestagel vzeti najmanj štiri ure pred ali najmanj štiri ure po sočasno uporabljenem zdravilu, da bi zmanjšali tveganje za zmanjšano absorpcijo sočasno uporabljenega zdravila.
Genzyme Europe B.V. Paasheuvelweg 25, 1105 BP Amsterdam The Netherlands 
Paasheuvelweg 25, 1105 BP Amsterdam Nizozemska
Therefore, patients taking both ciclosporin and Cholestagel should have their blood concentrations monitored prior to and frequently after when Cholestagel therapy is stopped with their ciclosporin dose adjusted accordingly. 
Zato je potrebno pri bolnikih, ki hkrati jemljejo ciklosporin in zdravilo Cholestagel, izvajati kontrolne meritve vrednosti v krvi pred zdravljenjem in nato pogosto po prenehanju zdravljenja z zdravilom Cholestagel; odmerek ciklosporina pa mora biti ustrezno prilagojen.
STATEMENT OF ACTIVE SUBSTANCE(S) Each tablet contains 625 mg of colesevelam (as hydrochloride). 
NAVEDBA ENE ALI VEČ ZDRAVILNIH UČINKOVIN Vsaka tableta vsebuje 625 mg holesevelama (v obliki holesevelamijevega klorida).
DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION 
DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Z ZDRAVILOM Datum prve odobritve: 10. marec 2004
High density polyethylene bottles with a polypropylene cap. 
Plastenke iz polietilena visoke gostote s pokrovom iz polipropilena z ali zunanje ovojnine.
The recommended starting dose of Cholestagel is 6 tablets per day taken as 3 tablets twice per day with meals or 6 tablets once per day with a meal. 
Priporočeni začetni odmerek je 6 tablet dnevno, ki se vzamejo kot 3 tablete dvakrat dnevno, ob obrokih, ali 6 tablet enkrat dnevno, ob obroku.
Additionally, if you have any condition that could cause you to have a deficiency of vitamins A, D, E or K, your doctor may want to check your vitamin levels periodically while you are taking Cholestagel. 
Poleg tega vam bo med jemanjem zdravila Cholestagel zdravnik morda želel občasno preveriti koncentracije vitaminov, če imate bolezen, ki bi lahko povzročila pomanjkanje vitaminov A, D, E ali K. Če bo potrebno, vam bo svetoval jemanje vitaminskih nadomestkov.
Cholestagel in combination with statins and in combination with ezetimibe was well tolerated and the adverse reactions observed were consistent with the known safety profile of statins or ezetimibe alone. 
Ugotovljeni neželeni učinki so bili skladni z znanim varnostnim profilom statinov samih oz. ezetimiba samega.
Olmesartan should be administered at least 4 hours prior to colesevelam. 
Olmesartan je treba vzeti vsaj 4 ure pred zaužitjem holesevelama.
No interaction was observed when Cholestagel was administered at least four hours after levothyroxine. 
Niso opazili medsebojnega delovanja, če je bilo zdravilo Cholestagel vzeto najmanj štiri ure po levotiroksinu.
Glipizide should be administered at least 4 hours prior to colesevelam. 
Glipizid je potrebno vzeti vsaj 4 ure pred zaužitjem holesevelama.
As described in Section 2, if you will be taking Cholestagel along with another medicine it is possible that your doctor will advise you to take Cholestagel at least 4 hours before or at least 4 hours after taking the other medicine. 
Če boste med zdravljenjem z zdravilom Cholestagel jemali drugo zdravilo, vam bo morda zdravnik svetoval, da zdravilo Cholestagel vzamete najmanj 4 ure pred ali najmanj 4 ure po tem, ko ste vzeli druga zdravila, kot je opisano v poglavju 2.
The recommended dose for Cholestagel is 3 tablets taken twice a day with meals or 6 tablets a day with a meal. 
Priporočeni odmerek zdravila Cholestagel je 3 tablete dvakrat dnevno, ob obroku, ali 6 tablet enkrat dnevno, ob obroku.
This interaction was also observed when Cholestagel was administered one hour after the oral contraceptive pill. 
Tako medsebojno delovanje so opazili tudi, če je bilo zdravilo Cholestagel vzeto eno uro po peroralni kontracepcijski tabletki, vendar pa niso opazili medsebojnega delovanja, če je bilo zdravilo Cholestagel vzeto štiri ure po peroralni kontracepcijski tabletki.
The effect of 3.8 g Cholestagel plus 10 mg ezetimibe versus 10 mg ezetimibe alone on LDL-C levels was assessed in a multicentre, randomised, double-blind, placebo-controlled, parallel-group study in 86 patients with primary hypercholesterolaemia over a 6-week treatment period. 
V multicentrični, randomizirani, dvojno slepi, s placebom kontrolirani študiji vzporednih skupin s 86 bolniki s primarno hiperholesterolemijo so v 6 tednih zdravljenja ocenjevali učinek kombinacije 3,8 g zdravila Cholestagel in 10 mg ezetimiba v primerjavi z 10 mg ezetimiba samega na koncentracijo holesterola LDL.
There were no significant effects on growth, sexual maturation, fat-soluble vitamin levels or clotting factors, and the adverse reaction profile for Cholestagel was comparable to that seen with placebo. 
Ni bilo pomembnih učinkov na rast, spolno dozorevanje, koncentracijo v maščobi topnih vitaminov ali faktorjev strjevanja krvi.
Therefore glimepiride should be administered at least 4 hours prior to colesevelam. 
Zato je potrebno glimepirid vzeti vsaj 4 ure pred zaužitjem holesevelama.
Cholestagel had no effect on the bioavailability of lovastatin in an interaction study. 
V študiji interakcije so ugotovili, da zdravilo Cholestagel ni imelo učinka na biološko razpoložljivost lovastatina.
Cholesterol is the sole precursor of bile acids. 
Edini prekurzor žolčnih kislin je holesterol.
Constipation or bloating could occur. 
Lahko se pojavijo prebavne motnje.
Anticoagulant therapy 
Zdravljenje z antikoagulanti
No interaction was observed when Cholestagel was administered four hours after glyburide. 
Niso opazili medsebojnega delovanja, če je bilo zdravilo Cholestagel vzeto najmanj štiri ure po gliburidu.