natgillin/translations-raw huggingface dataset:
You can take Lamictal dispersible/chewable tablets by swallowing them whole with a little water, by chewing them, or by dissolving them in water: 
Lamictal disperzibilne/žvečljive tablete lahko vzamete tako, da jih pogoltnete cele z nekaj vode, jih prežvečite, ali jih raztopite v vodi:
Escalation and maintenance doses should be adjusted according to clinical response (see section 5.2). 
Zviševanje odmerkov in vzdrževalne odmerke morate prilagoditi kliničnemu odzivu (glejte poglavje 5.2).
Clearance and half-life are independent of dose. 
Očistek in razpolovni čas nista odvisna od odmerka.
Results of a population pharmacokinetic analysis including both young and elderly patients with epilepsy, enrolled in the same trials, indicated that the clearance of lamotrigine did not change to a clinically relevant extent. 
Rezultati populacijske farmakokinetične analize, ki je zajela mlade in starejše bolnike z epilepsijo, vključene v ista preskušanja, kažejo, da se očistek lamotrigina ni klinično pomembno spremenil.
Hormonal contraceptives (such as the Pill) can affect the way Lamictal works Your doctor may recommend that you use a particular type of hormonal contraceptive, or another method of contraception, such as condoms, a cap or a coil. 
Hormonska kontracepcija (npr. kontracepcijske tablete) lahko vpliva na delovanje zdravila Lamictal Zdravnik vam bo morda svetoval določeno vrsto hormonske kontracepcije ali uporabo kakšnega drugega načina kontracepcije, npr. kondomov, cervikalne kapice ali materničnega vložka.
The half-life of lamotrigine is greatly affected by concomitant medicinal products. 
Na razpolovni čas lamotrigina močno vplivajo sočasno uporabljana zdravila.
The mean half-life was estimated at 23 hours in infants younger than 26 months on enzyme-inducing therapy, 136 hours when co-administered with valproate and 38 hours in subjects treated without enzyme inducers/inhibitors. 
Ocenjeni povprečni razpolovni čas je bil 23 ur pri otrocih, mlajših od 26 mesecev in zdravljenih z induktorji encimov, 136 ur med sočasno uporabo z valproatom in 38 ur pri preiskovancih, ki niso dobivali induktorjev oz. zaviralcev encimov.
Don't stop unless your doctor advises you to. 
Ne nehajte ga jemati, če vam tega ne naroči zdravnik.
The benefit/risk ratio of adjunctive treatment of partial and generalised seizures in adults and adolescents aged 13 years and above, was confirmed to be positive. 
Potrjeno je bilo, da je razmerje med koristmi in tveganji dopolnilnega zdravljenja delnih in generaliziranih napadov pri odraslih in mladostnikih, starih 13 let in več, pozitivno.
The group concurred that theoretically a mood stabiliser should be able to prevent both manic and depressive recurrences, the characteristic features of Bipolar Disorder, but as of now we do not possess such an ideal mood stabiliser. 
Skupina se je strinjala, da bi teoretično moral biti stabilizator razpoloženja sposoben preprečevati ponovitve maničnih in depresivnih epizod, ki so značilne za bipolarno motnjo, vendar trenutno še ne razpolagamo s takšnim idealnim stabilizatorjem razpoloženja.
• if you are allergic (hypersensitive) to lamotrigine or any of the other ingredients of Lamictal (listed in Section 6). 
• če ste alergični na (preobčutljivi za) lamotrigin ali katerokoli sestavino zdravila Lamictal (pomožne snovi so navedene v poglavju 6).
Lamotrigine is rapidly and completely absorbed from the gut with no significant first-pass metabolism. 
Lamotrigin se iz črevesa absorbira hitro in popolnoma in nima pomembne presnove prvega prehoda.
If this applies to you: Î Tell your doctor, and don't take Lamictal. 
Če to velja za vas: Î Povejte svojemu zdravniku in ne vzemite zdravila Lamictal.
Hepatic dysfunction usually occurs in association with hypersensitivity reactions but isolated cases have been reported without overt signs of hypersensitivity. 
Moteno delovanje jeter se ponavadi pojavi skupaj s preobčutljivostnimi reakcijami, vendar so bili opisani tudi posamezni primeri brez očitnih znakov preobčutljivosti.
Should a woman decide to breast-feed while on therapy with lamotrigine, the infant should be monitored for adverse effects. 
Če se ženska odloči, da bo med zdravljenjem z lamotriginom dojila, je treba dojenčka nadzirati glede neželenih učinkov.
In patients with bipolar disorder, worsening of depressive symptoms and/or the emergence of suicidality may occur whether or not they are taking medications for bipolar disorder, including Lamictal. 
Pri bolnikih z bipolarno motnjo se lahko pojavi poslabšanje depresivnih simptomov in/ali samomorilnost ne glede na to, ali jemljejo zdravila za bipolarno motnjo, vključno z zdravilom Lamictal.
Your doctor may advise you to take extra folic acid if you're planning to become pregnant and while you're pregnant. 
Zdravnik vam bo morda svetoval, da jemljete dodatno folno kislino, če nameravate zanositi in med nosečnostjo.
• Add a little more water to the glass and drink that, to make sure you've taken all the medicine. 
• Nalijte v kozarec še malo vode in jo popijte, da boste res zaužili vse zdravilo.
Thirty-eight responders (> 40% decrease in seizure frequency) were randomised to placebo or continuation of lamotrigine. 
38 bolnikov, ki so se odzvali (tj. se jim je pogostnost napadov zmanjšala za > 40 %), so randomizirali na placebo ali nadaljnje jemanje lamotrigina.
In a study of subjects with Gilbert's Syndrome, mean apparent clearance was reduced by 32% compared with normal controls but the values are within the range for the general population. 
V študiji preiskovancev z Gilbertovim sindromom je bil povprečni navidezni očistek 32 % manjši kot pri zdravih kontrolnih osebah, a vrednosti so bile znotraj razpona za splošno populacijo.
Table 1: Adults and adolescents aged 13 years and above - recommended treatment regimen in epilepsy 
Preglednica 1: Odrasli in mladostniki od 13. leta naprej - priporočeni režim zdravljenja pri epilepsiji.
Study SCAB2006 had a similar design as study SCAB2003, but differed from study SCAB2003 in evaluating a flexible dose of lamotrigine (100 to 400 mg/day) and including patients with bipolar I disorder who had recently or were currently experiencing a manic episode. 
Načrt študije SCAB2006 je bil podoben načrtu študije SCAB2003, vendar se je od študije SCAB2003 razlikovala po tem, da je ocenjevala spremenljiv odmerek lamotrigina (od 100 do 400 mg/dan) in je vključila bolnike z bipolarno motnjo I, ki so pred kratkim ali imajo trenutno manično epizodo.
The usual effective dose of Lamictal for adults and children aged over 12 years is between 100 mg and 400 mg each day. 
Učinkoviti odmerek zdravila Lamictal za odrasle in otroke, starejše od 12 let, je ponavadi med 100 in 400 mg na dan.
These data indicate that lamotrigine does not influence the pharmacokinetics of levetiracetam and that levetiracetam does not influence the pharmacokinetics of lamotrigine. 
Ti podatki kažejo, da lamotrigin ne vpliva na farmakokinetiko levetiracetama, levetiracetam pa ne vpliva na farmakokinetiko lamotrigina.
Dihydrofolate reductase 
Dihidrofolat-reduktaza
The interaction between other oral contraceptive or HRT treatments and lamotrigine have not been studied, though they may similarly affect lamotrigine pharmacokinetic parameters. 
Interakcije med drugimi peroralnimi kontraceptivi ali HNZ in lamotriginom niso raziskane, vendar lahko podobno vplivajo na farmakokinetične parametre lamotrigina.
Lamotrigine did not cause QT prolongation in animals at exposures up to approximately two-times the maximum therapeutic free concentration. 
Lamotrigin ni podaljšal intervala QT pri živalih, izpostavljenih do približno dvakratne največje terapevtske proste koncentracije.
If you have missed taking a dose of Lamictal: Î Ask your doctor for advice on how to start taking it again. 
Če pozabite vzeti odmerek zdravila Lamictal: Î Z zdravnikom se posvetujte, kako naj znova začnete jemati zdravilo.
If you stop taking Lamictal, your dose will not need to be reduced gradually. 
Če prenehate jemati zdravilo Lamictal, vam odmerka ni treba zmanjševati postopoma.
• a sore mouth or eyes 
• vnetje ust ali oči
1 What Lamictal is and what it is used for 2 Before you take Lamictal 3 How to take Lamictal 4 Possible side effects 5 How to store Lamictal 6 Further information 
1 Kaj je zdravilo Lamictal in za kaj ga uporabljamo 2 Kaj morate vedeti, preden boste vzeli zdravilo Lamictal 3 Kako jemati zdravilo Lamictal 4 Možni neželeni učinki
These include: 
Ob upoštevanju naslednjega:
Behavioural events were more common in males. 
Vedenjski učinki so bili pogostejši pri moških.
It is recommended to gradually decrease the daily dose of lamotrigine by 50100 mg each week (at a rate not exceeding 25% of the total daily dose per week) over a period of 3 weeks, unless the clinical response indicates otherwise. 
Priporočljivo je, da dnevni odmerek lamotrigina postopno znižujete za 50-100 mg na teden (in ne za več kot 25 % celotnega dnevnega odmerka na teden) v obdobju 3 tednov, če klinični odziv ne narekuje drugače.
If you are using a hormonal contraceptive, and you notice any changes in your menstrual pattern, such as breakthrough bleeding or spotting between periods: Î Tell your doctor. 
Če uporabljate hormonsko kontracepcijo in opazite kakšne spremembe v menstruaciji, npr. vmesne krvavitve ali krvav izcedek med eno in drugo menstruacijo: Î Povejte zdravniku.
Table 2: Children and adolescents aged 2 to 12 years - recommended treatment regimen in epilepsy (total daily dose in mg/kg body weight/day) 
Preglednica 2: Otroci in mladostniki od 2. do 12. leta starosti - priporočeni režim odmerjanja pri epilepsiji (celotni dnevni odmerek v mg/kg telesne mase/dan)
For adults aged 18 years and over, Lamictal can be used on its own or with other medicines, to prevent the periods of depression that occur in bipolar disorder. 
Pri odraslih od 18. leta dalje je mogoče Lamictal sam ali skupaj z drugimi zdravili uporabljati za preprečevanje obdobij depresije, ki se pojavljajo pri bipolarni motnji.
Lamictal treats epilepsy by blocking the signals in the brain that trigger epileptic seizures (fits). 
Lamictal zdravi epilepsijo tako, da v možganih zavre signale, ki sprožijo epileptični napad (napad krčev).
There are limited data on the efficacy and safety of lamotrigine for adjunctive therapy of partial seizures in children aged 1 month to 2 years (see section 4.4). 
Na voljo je le malo podatkov o učinkovitosti in varnosti lamotrigina kot dodatnega zdravljenja parcialnih napadov pri otrocih v starosti od 1 meseca do 2 let (glejte poglavje 4.4).
Lithium Buproprion Olanzapine 
zonisamid litij buproprion olanzapin
In 143 paediatric patients aged 2 to 26 months, weighing 3 to 16 kg, clearance was reduced compared to older children with the same body weight, receiving similar oral doses per kg body weight as children older than 2 years. 
Pri 143 pediatričnih bolnikih, starih od 2 do 26 mesecev, s telesno težo od 3 do 16 kg, je bil očistek manjši kot pri starejših otrocih z enako telesno težo, ob uporabi podobnih peroralnih odmerkov na kilogram telesne teže kot pri otrocih, starejših od 2 let.
Time to maximum concentration is slightly delayed after food but the extent of absorption is unaffected. 
Čas do največje koncentracije se po zaužitju na poln želodec nekoliko podaljša, delež absorpcije pa se ne spremeni.
It is important to note that early manifestations of hypersensitivity (for example fever, lymphadenopathy) may be present even though rash is not evident. 
Zavedati se je treba, da so lahko zgodnji znaki preobčutljivosti (npr. zvišana telesna temperatura, limfadenopatija) prisotni, tudi če izpuščaj ni opazen.
But you should still talk to your doctor first, if you want to stop taking Lamictal. 
Kljub temu se morate najprej posvetovati z zdravnikom, če želite opustiti jemanje zdravila Lamictal.
Measurement of serum FSH, LH and oestradiol during the study indicated some loss of suppression of ovarian hormonal activity in some women, although measurement of serum progesterone indicated that there was no hormonal evidence of ovulation in any of the 16 subjects. 
Merjenje FSH, LH in estradiola v serumu med študijo je pri nekaterih preiskovankah pokazalo zmanjšanje supresije hormonske aktivnosti jajčnikov, čeprav meritve progesterona, v serumu pri nobeni od 16 preiskovank, niso pokazale hormonskih znakov ovulacije.
But you must be aware that they are potentially serious - so, if you notice any of these symptoms: 
Vendar se morate zavedati, da so lahko resni, zato v primeru, da opazite katerega od teh simptomov: Î Čim prej pojdite k zdravniku.
• if you have problems with your kidneys 
• če imate težave z ledvicami,
- Seizures associated with Lennox-Gastaut syndrome. 
- Napadi, povezani z Lennox-Gastautovim sindromom.
In a pooled analysis of psychiatric indications, events were more common in the first month of treatment, in patients taking lamotrigine. 
V kumulativni analizi psihiatričnih indikacij so bili ti pojavi pogostejši prvi mesec zdravljenja in pri bolnikih, ki so jemali lamotrigin.
Hence an article 30 procedure (Directive 2001/83/EC) for harmonisation of the SPC of lamotrigine across Europe has been initiated by the Marketing Authorisation Holder. 
Iz tega razloga je imetnik dovoljenja za promet z zdravilom v skladu s členom 30 (Direktive 2001/83/ES) sprožil postopek za uskladitev povzetka glavnih značilnosti zdravila za lamotrigin v vsej Evropi.
• a rare skin condition, with severe blisters, and bleeding from the lips, eyes, mouth, nose and genital area (Stevens-Johnson syndrome). 
• redka bolezen kože s hudimi mehurji, krvavitvami iz ustnic, oči, ust, nosu in spolovil (StevensJohnsonov sindrom)
If the calculated dose of lamotrigine (for example for treatment of children with epilepsy or patients with hepatic impairment) does not equate to whole tablets, the dose to be administered is that equal to the lower number of whole tablets. 
Če se izračunani odmerek lamotrigina (npr. za zdravljenje otrok z epilepsijo ali bolnikov z okvaro jeter) ne izide na celotno tableto, morate uporabiti odmerek, ki ustreza navzdol zaokroženemu številu celih tablet.
30 tablets 50 tablets 56 tablets 60 tablets 90 tablets 100 tablets 
30 tablet 50 tablet 56 tablet 60 tablet 90 tablet 100 tablet
Do not use Lamictal after the expiry date shown on the blisters, carton or bottle. 
Zdravila Lamictal ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na pretisnih omotih, škatli ali steklenički.
Weeks 1 + 2 Weeks 3 + 4 Usual maintenance dose 
1. in 2. teden 3. in 4. teden Običajni vzdrževalni odmerek
Therapy with multiple AEDs is associated with a higher risk of congenital malformations than monotherapy and therefore monotherapy should be used whenever possible. 
Zdravljenje z več antiepileptiki spremlja večje tveganje za kongenitalne malformacije v primerjavi z monoterapijo, zato je treba uporabiti monoterapijo, kadar je to le mogoče.
A study in healthy adult volunteers evaluated the effect of repeat doses of lamotrigine (up to 400 mg/day) on cardiac conduction, as assessed by 12-lead ECG. 
V študiji pri zdravih odraslih prostovoljcih so ocenili učinek ponavljajočih se odmerkov lamotrigina (do 400 mg/dan) na prevajanje v srcu, ki so ga ovrednotili z EKG z 12 odvodi.
Two volunteer studies have demonstrated that the effect of lamotrigine on fine visual motor co-ordination, eye movements, body sway and subjective sedative effects did not differ from placebo. 
Dve študiji s prostovoljci sta pokazali, da se vpliv lamotrigina na fino vizualno-motorično koordinacijo, gibe oči, nihanje telesa in subjektivne sedativne učinke ne razlikuje od placeba.
Your doctor will start you on a low dose, and gradually increase the dose over a few weeks until you reach a dose that works for you (called the effective dose). 
Zdravnik vam bo sprva predpisal majhen odmerek, potem pa ga bo v teku nekaj tednov postopoma povečeval, dokler ne boste dosegli za vas učinkovitega odmerka.
Once stabilised using lamotrigine monotherapy or adjunctive therapy, patients were randomly assigned into one of five treatment groups: lamotrigine (50, 200, 400 mg/day), lithium (serum levels of 0.8 to 1.1 mMol/L) or placebo for a maximum of 76 weeks (18 months). 
Ko se je stanje z monoterapijo z lamotriginom ali dodatno terapijo stabilizirano, so bolnike naključno razvrstili v eno od petih terapevtskih skupin: lamotrigin (50, 200, 400 mg/dan), litij (serumske koncentracije od 0,8 do 1,1 mmol/l) ali placebo za največ 76 tednov (18 mesecev).
Middlesex UB11 1BT United Kingdom 
Middlesex UB11 1BT Velika Britanija
In fact, according to available data the mood stabilising property of lamotrigine appears to be due to the prevention of depressive episodes and not to the prevention of manic episodes. 
V skladu z razpoložljivimi podatki se zdi, da je sposobnost lamotrigina za stabilizacijo razpoloženja dejansko povezana s preprečevanjem epizod depresije in ne s preprečevanjem maničnih epizod.
Certain patients, such as those with a history of suicidal behaviour or thoughts, young adults, and those patients exhibiting a significant degree of suicidal ideation prior to commencement of treatment, may be at a greater risk of suicidal thoughts or suicide attempts, and should receive careful monitoring during treatment. 
Pri nekaterih bolnikih, npr. tistih z anamnezo samomorilnega vedenja ali samomorilnih misli, mladih odraslih bolnikih in bolnikih, ki kažejo znatno stopnjo samomorilne miselnosti pred uvedbo zdravljenja, lahko obstaja večje tveganje za pojav samomorilnih misli ali poskusov samomora.
When stopping hormonal contraceptives, the clearance of lamotrigine may be halved. 
Po prenehanju uporabe hormonskih kontraceptivov se lahko očistek lamotrigina prepolovi.
A single dose pharmacokinetic study was performed in 24 subjects with various degrees of hepatic impairment and 12 healthy subjects as controls. 
Farmakokinetična študija s posameznimi odmerki je bila narejena pri 24 preiskovancih z različno stopnjo okvare jeter in pri 12 zdravih preiskovancih kot kontrolnih oseb.
Patients taking other preparations containing lamotrigine 
Bolniki, ki jemljejo druga zdravila, ki vsebujejo lamotrigin
In children taking lamotrigine for the treament of typical absence seizures, efficacy may not be maintained in all patients. 
Pri otrocih, ki jemljejo lamotrigin za zdravljenje značilnih absenčnih napadov, je mogoče, da se učinkovitost ne ohrani pri vseh bolnikih.
Lamotrigine at 200 mg did not affect the pharmacokinetics of olanzapine. 
Lamotrigin v odmerku 200 mg ni vplival na farmakokinetiko olanzapina.
It is indicated as monotherapy as well as adjuvant therapy in partial seizures with or without secondary generalisation, primary generalised seizures and some specific seizure types. 
Indicirana je kot monoterapija in kot adjuvantno zdravilo pri delnih napadih s sekundarno generalizacijo ali brez nje, pri primarno generaliziranih napadih in nekaterih specifičnih vrstah napadov.
For children aged 2 to 12 years, the effective dose depends on their body weight - usually, it's between 1 mg and 15 mg for each kilogram of the child's weight, up to a maximum of 400 mg daily. 
Pri otrocih od 2. do 12. leta starosti je učinkoviti odmerek odvisen od njihove telesne teže; ponavadi je med 1 in 15 mg na kilogram otrokove telesne teže, do največ 400 mg na dan.
Never take more Lamictal than your doctor tells you to. 
Nikoli ne vzemite več Lamictala, kot vam je naročil zdravnik.
Therefore patients should be instructed to promptly report changes in their menstrual pattern, i.e. breakthrough bleeding. 
Zato morate bolnicam naročiti, naj takoj sporočijo spremembe v menstruacijskem ciklusu, npr. vmesne krvavitve.
For AEDs where no such data are available, a similar association with suicide-related events cannot be excluded. 
Pri antiepileptičnih zdravilih, za katera takšnih podatkov ni, ni mogoče izključiti podobnih spremljajočih s samomorom povezanih dogodkov.
Peak plasma concentrations occur approximately 2.5 hours after oral administration of lamotrigine. 
Največjo koncentracijo v plazmi doseže približno 2,5 ure po peroralni uporabi lamotrigina.
Serum levels were measured at the end of week 2 of titration and the subsequent dose either reduced or not increased if the concentration exceeded 0.41 µg/mL, the expected concentration in adults at this time point. 
Nadaljnji odmerek so potem bodisi zmanjšali ali ga niso povečali, če je koncentracija presegla 0,41 µg/ml, kar je pričakovana koncentracija pri odraslih ob tem času.
pain, back pain. 
bolečine, bolečine v hrbtu.
The impact of the modest increase in levonorgestrel clearance, and the changes in serum FSH and LH, on ovarian ovulatory activity is unknown (see section 4.4). 
Vpliv zmernega povečanja očistka levonorgestrela in sprememb FSH in LH v serumu na ovulacijsko aktivnost jajčnikov ni znan (glejte poglavje 4.4).
Based on a retrospective analysis of plasma levels in patients who received lamotrigine both with and without gabapentin, gabapentin does not appear to change the apparent clearance of lamotrigine. 
Retrospektivna analiza plazemske koncentracije pri bolnikih, ki so dobivali lamotrigin z gabapentinom in brez njega, kaže, da gabapentin ne spreminja navideznega očistka lamotrigina.
It is used to treat two conditionsepilepsy and bipolar disorder. 
Uporabljamo ga za zdravljenje dveh bolezniepilepsije in bipolarne motnje.
• if you have ever developed a rash when you've taken lamotrigine or other medicines for epilepsy 
• če se vam je kdaj pojavil izpuščaj med jemanjem lamotrigina ali drugih zdravil proti epilepsiji,
If you are taking Lamictal for epilepsy 
Če jemljete Lamictal za epilepsijo
When the interval since discontinuing lamotrigine exceeds five half-lives (see section 5.2), Lamictal should generally be escalated to the maintenance dose according to the appropriate schedule. 
Če je čas od prekinitve lamotrigina daljši od petih razpolovnih časov (glejte poglavje 5.2), je treba Lamictal praviloma zviševati do vzdrževalnega odmerka po ustrezni shemi.
Table 6: Effects of other medicinal products on glucuronidation of lamotrigine 
Preglednica 6: Vpliv drugih zdravil na glukuronidacijo lamotrigina
• whether you are taking Lamictal with other medicines 
• tega, ali jemljete Lamictal z drugimi zdravili,
In a study in healthy volunteers, lopinavir/ritonavir approximately halved the plasma concentrations of lamotrigine, probably by induction of glucuronidation. 
V študiji zdravih prostovoljcev je lopinavir/ritonavir približno prepolovil plazemsko koncentracijo lamotrigina, verjetno z indukcijo glukuronidacije.
• rapid, uncontrollable eye movements (nystagmus) 
• hitro, neobvladljivo gibanje zrkel (nistagmus)
- high initial doses of lamotrigine and exceeding the recommended dose escalation of lamotrigine therapy (see section 4.2) - concomitant use of valproate (see section 4.2). 
- visokimi začetnimi odmerki lamotrigina in prekoračenjem priporočenega zviševanja odmerka lamotrigina (glejte poglavje 4.2), - sočasno uporabo valproata (glejte poglavje 4.2).
82104 Bratislava Slovakia 
Galvaniho 7/A 82104 Bratislava Slovaška
They are marked ‘LTG' above the number ‘2' on one side; and with two ovals overlapping at right angles on the other. 
Na eni strani imajo oznako 'LTG' nad številko '2', na drugi pa dve elipsi, ki se prekrivata pod pravim kotom.
These may be signs that Lamictal is affecting the way your contraceptive is working. 
To so lahko znaki, da zdravilo Lamictal vpliva na delovanje vaše hormonske kontracepcije.
Precautions relating to epilepsy 
Previdnostni ukrepi pri epilepsiji
• a combination of lopinavir and ritonavir, used to treat Human Immunodeficiency Virus 
• kombinacija lopinavirja in ritonavirja, ki se uporablja za zdravljenje okužbe z virusom človeške imunske pomanjkljivosti (HIV),
agitation, unsteadiness, movement disorders, worsening of Parkinson's disease, extrapyramidal effects, choreoathetosis, increase in seizure frequency. 
agitacija, negotovost pri gibanju, motnje gibanja, poslabšanje Parkinsonove bolezni, ekstrapiramidalni učinki, horeoatetoza, pogostejši epileptični napadi.