natgillin/translations-raw huggingface dataset:
Common side effects (may affect up to 1 in 10 people): allergic reactions dry mouth and skin throat infections dry eyes bladder and skin infections sweating shingles feeling weak and unwell inflammation of the breast anxiety inflammation of the liver depression kidney disorders abnormal thinking increased muscle tone or tension asthma 
Očesne bolezni konjunktivitis zelo pogosto povečano solzenje zelo pogosto suhe oči pogosto edem papile vidnega živca neznano retinalna krvavitev neznano
Pericardial effusion 
• odpoved ledvic
1Heart beat irregular 
1nereden srčni utrip zelo pogosto
After a median follow-up of 12 months, the hazard ratio (HR) for disease-free survival (DFS) was 0.54 (95% CI 0.44, 0.67) which translates into an absolute benefit, in terms of a 2-year disease-free survival rate, of 7.6 percentage points (85.8% versus 78.2%) in favour of the trastuzumab arm. 
Po mediano 12-mesečnem spremljanju je bilo razmerje ogroženosti za preživetje brez bolezni 0,54 (95-% IZ: 0,44; 0,67).
Faint/barely perceptible membranous reactivity in ≥ 10% of tumour cells; cells are reactive only in part of their membrane 
Bledo, komaj zaznavno obarvanje membrane je prisotno pri ≥ 10 % tumorskih celic.
Orthopnoea 
Imunogenost
Skin and subcutaneous tissue disorders 
• okužbe mehurja in kože znojenje
Neutropenia 
Odmerjanje
The relationship between fluconazole use and these events is unclear. 
Povezava med flukonazolom in temi dogodki ni jasna.
Adopted at the 6-9 February 2017 PRAC 
Sprejeto na seji odbora PRAC med 6. in 9. februarjem 2017
Nivolumab - Pemphigoid (EPITT no 18759) 
Nivolumab - pemfigoid (EPITT št. 18759)
Undesirable effects e Rash is a composite term which includes maculopapular rash, rash erythematous, rash pruritic, rash follicular, rash macular, rash morbilliform, rash papular, rash pustular, rash papulosquamous, rash vesicular, rash generalised, dermatitis, dermatitis acneiform, dermatitis allergic, dermatitis atopic, dermatitis bullous, dermatitis exfoliative, dermatitis psoriasiform, and drug eruption and pemphigoid. 
Neželeni učinki e Izpuščaj je sestavljen izraz, ki vključuje makulopapulozni izpuščaj, eritemski izpuščaj, srbeči izpuščaj, folikularni izpuščaj, makulozni izpuščaj, morbiliformni izpuščaj, papulozni izpuščaj, pustulozni izpuščaj, papuloskvamozni izpuščaj, vezikulozni izpuščaj, generalizirani izpuščaj, dermatitis, akneiformni dermatitis, alergijski dermatitis, atopični dermatitis, bulozni dermatitis, eksfoliativni dermatitis, psoriaziformni dermatitis, in medikamentni izpuščaj in pemfigoid.
An observational study has suggested an increased risk of spontaneous abortion in women treated with fluconazole during the first trimester. 
Opazovalna študija kaže na povečano tveganje spontanega splava pri ženskah, zdravljenih s flukonazolom v prvem trimesečju.
There have been reports of multiple congenital abnormalities (including brachycephalia, ears dysplasia, giant anterior fontanelle, femoral bowing and radio-humeral synostosis) in infants whose mothers were treated for at least three or more months with high doses (400-800 mg daily) of fluconazole for coccidioidomycosis. 
Poročali so o multiplih kongenitalnih anomalijah (vključno z brahicefalijo, displazijo ušes, veliko sprednjo fontanelo, upognjenostjo stegnenice in radio-humeralno sinostozo) pri dojenčkih, katerih matere so najmanj tri mesece ali več dobivale velike odmerke (od 400 do 800 mg/dan) flukonazola za zdravljenje kokcidioidomikoze.
Data from several hundred pregnant women treated with standard doses (<200 mg/day) of fluconazole, administered as a single or repeated dose in the first trimester, show no increased risk of undesirable effects in the foetus. 
Podatki, dobljeni pri več sto nosečnicah, zdravljenih z običajnimi odmerki flukonazola (< 200 mg/dan) v enkratnem ali večkratnih odmerkih v prvem trimesečju nosečnosti, niso pokazali nobenih neželenih učinkov pri plodu.
Fluconazole in high dose and/or in prolonged regimens should not be used during pregnancy except for potentially life-threatening infections. 
Flukonazol se v velikih odmerkih in/ali pri dolgotrajnem zdravljenju ne sme uporabljati med nosečnostjo, razen v primeru potencialno življenjsko ogrožajočih okužb.
Fluconazole in standard doses and short-term treatments should not be used in pregnancy unless clearly necessary. 
Flukonazol se v običajnih odmerkih in pri kratkotrajnem zdravljenju ne sme uporabljati med nosečnostjo, razen če to ni nujno potrebno.
4 - Possible side effects Skin rash sometimes with blisters, itching 
Navodilo za uporabo 4 - Možni neželeni učinki Kožni izpuščaj, včasih z mehurčki, srbenje
Fluconazole - Spontaneous abortion and stillbirth (EPITT no 18666) 
Flukonazol - spontani splav in mrtvorojenost (EPITT št.
Water may be given. 
Lahko se jim ponudi voda.
The stopper may be safely punctured up to 100 times. 
Zamašek lahko varno prebodete do 100-krat.
The following doses are recommended: 
Priporočeni so naslednji odmerki:
SPECIAL WARNINGS, IF NECESSARY 
POSEBNA OPOZORILA, ČE SO POTREBNA
At maximal effect, the animal is relaxed, recumbent and does not respond to external stimulus. 
Pri največjem učinku je žival sproščena, neaktivna in se ne odziva na zunanje dražljaje.
Spontaneous recovery occurs within 3 hours. 
Do spontanega prenehanja delovanja pride v treh urah.
Frequent and regular monitoring of respiratory and cardiac function should be performed. 
Pogosto in redno spremljajte dihanje in delovanje srca.
In a clinical study, the requirement for propofol was reduced by 50%. 
V klinični študiji je bila potreba po propofolu zmanjšana za 50 %.
Do not use in animals with severe systemic disease or in animals that are moribund. 
Ne uporabite pri živalih s hudimi sistemskimi boleznimi ali pri umirajočih živalih.
Blood pressure will increase initially and then return to normal or below normal. 
Krvni pritisk se najprej poviša in se nato vrne na normalno raven ali pod njo.
The eyes should be protected by a suitable eye lubricant. 
Oči morate zaščititi z ustreznim mazilom za oči.
If symptoms occur, seek the advice of a physician. 
Če se pojavijo simptomi, poiščite zdravniško pomoč.
*only intramuscularly 
*samo intramuskularno
However this duration is dependent on a number of variables and further analgesia should be administered in accordance with clinical judgement. 
Vendar je njeno trajanje odvisno od številnih dejavnikov, zato je treba nadaljnjo analgezijo dajati glede na klinično presojo.
It is also advisable to have oxygen readily available, should hypoxaemia be detected or suspected. 
Priporočljivo je imeti na voljo kisik, če bi se pojavila hipoksemija ali če bi posumili nanjo.
Sympathetic neurotransmission is prevented and the level of consciousness decreases. 
Tako se prepreči simpatetična nevrotransmisija in zniža raven zavesti.
Within 15 minutes dogs and cats are normally awake and standing. 
Psi in mačke so navadno budni in stojijo po 15 minutah.
All known metabolites lack pharmacological activity. 
Vsi znani presnovki so brez farmakološke aktivnosti.
In case of skin or mucosal contact, wash the exposed skin immediately after exposure with large amounts of water and remove contaminated clothes that are in direct contact with skin. 
V primeru stika s kožo ali sluznico izpostavljen del nemudoma sperite z veliko količino vode in odstranite umazana oblačila, ki so v neposrednem stiku s kožo.
The maximum plasma concentration is reached about 0.24 h after intramuscular administration. 
Najvišja koncentracija v plazmi je dosežena približno 0,24 ure po intramuskularnem dajanju.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements. 
Vsako neporabljeno zdravilo za uporabo v veterinarski medicini ali odpadne snovi, ki nastanejo iz teh zdravil, je treba odstraniti v skladu z nacionalnimi zahtevami.
According to studies in rats, the maximum concentration in the central nervous system is several times that of the corresponding concentration in plasma. 
Raziskave na podganah kažejo, da je najvišja koncentracija v osrednjem živčevju nekajkrat višja kot ustrezna koncentracija v plazmi.
Respiration rate can occasionally decrease. 
Občasno lahko pride do zmanjšanja hitrosti dihanja.
For any information about this veterinary medicinal product, please contact the local representative of the marketing authorisation holder. 
Za vse nadaljnje informacije o tem zdravilu se obrnite na krajevno predstavništvo imetnika dovoljenja za promet z zdravilom.>
The elimination half-life (t1⁄2) is 40-50 minutes. 
Razpolovni čas izločanja (t1⁄2) je 40-50 minut.
Respiratory and haemodynamic symptoms should be treated symptomatically. 
Dihalne in hemodinamične simptome je treba zdraviti simptomatsko.
Pulse oximetry may be useful but is not essential for adequate monitoring. 
Pulzna oksimetrija je lahko ustrezen, vendar ne nujen način spremljanja teh funkcij.
In a clinical study, dexmedetomidine contributed to postoperative analgesia for 0.5 - 4 hours. 
V klinični študiji je deksmedetomidin prispeval k pooperativni analgeziji, ki je trajala 0,5-4 ure.
The veterinary medicinal product is not intended for repeat injections. 
Zdravilo za uporabo v veterinarski medicini ni namenjeno za ponavljajoče injiciranje.
Ventricular arrhythmias have also been reported. 
Poročali so tudi o ventrikularni aritmiji.
After treatment, the animal should not be given water or food before it is able to swallow. 
Po zdravljenju se živalim, dokler ne morejo požirati, ne daje voda ali hrana.
The bioavailability of dexmedetomidine is 60% and the apparent volume of distribution (Vd) is 0.9 l/kg. 
Biološka razpoložljivost deksmedetomidina je 60-odstotna in navidezni volumen porazdelitve (Vd) je 0,9 l/kg.
The duration and depth of the sedation and analgesia are dose-dependent. 
Trajanje in globina sedacije in analgezije sta odvisna od odmerka.
For deep sedation and analgesia with butorphanol 
Za globoko sedacijo in analgezijo z butorfanolom
Nervous, aggressive or excited animals should be given the possibility to calm down before initiation of treatment. 
Pri razdraženih, agresivnih ali razburjenih živalih počakajte, da se pomirijo, preden začnete zdravljenje.
Dexmedetomidine is a potent and selective α2-adrenoceptor agonist that inhibits the release of noradrenaline from noradrenergic neurons. 
Deksmedetomidin je močan in selektiven agonist α2-adrenoreceptorjev, ki zavira sproščanje noradrenalina iz noradrenergičnih nevronov.
Metabolites are excreted mainly in the urine (51% of the dose), and to a lesser extent in the faeces. 
Presnovki se izločajo večinoma z urinom (51 % odmerka) in v manjši meri z blatom.
Do not use in animals with cardiovascular disorders. 
Ne uporabite pri živalih z boleznimi srca in ožilja.
<{MM/YYYY}> 
<{MM/LLLL}>
To be used with precaution in elderly animals. 
Bodite previdni pri uporabi pri starejših živalih.
The mean half-life of elimination of dexmedetomidine increased to 1.6 h and the total exposure (AUC) increased by 50%. 
Srednja vrednost razpolovnega časa izločanja deksmedetomidina se je povečala na 1,6 ure, skupna izpostavljenost (AUC) pa za 50 %.
Pharmacotherapeutic group: Psycholeptics, hypnotics and sedatives ATCvet code: QN05CM18 
Farmakoterapevtska skupina: Psiholeptiki, hipnotiki in sedativi Oznaka ATCvet: QN05CM18.
It is recommended that animals are fasted for 12 hours prior to Cepedex administration. 
Priporočeno je, da se živali postijo 12 ur pred uporabo zdravila Cepedex.
4.10 Overdose (symptoms, emergency procedures, antidotes) 
4.10 Preveliko odmerjanje (simptomi, nujni ukrepi, protistrupi)
Sodium hydroxide (E 524) (for pH adjustment) Hydrochloric acid (E507) (for pH adjustment) Water for injections 
Natrijev hidroksid (E 524) (za uravnavo pH) Klorovodikova kislina (E 507) (za uravnavo pH) Voda za injekcije
In clinical trials the incidence of hypoxaemia was common, especially within the 15 first minutes into dexmedetomidine-ketamine anaesthesia. 
Pri kliničnih raziskavah je bila hipoksemija pogosta, zlasti v prvih 15 minutah deksmedetomidino-ketaminske anestezije.
Dogs: Dexmedetomidine doses are based on body surface area: 
Psi: Odmerki deksmedetomidina temeljijo na telesni površini.
The administration of dexmedetomidine to puppies younger than 16 weeks and kittens younger than 12 weeks has not been studied. 
Uporaba deksmedetomidina pri kužkih, mlajših od 16 tednov, in mačkah, mlajših od 12 tednov, ni bila preučena.
In case of eye contact, rinse abundantly with fresh water. 
V primeru stika z očmi jih dobro sperite s svežo vodo.
THE WORDS "FOR ANIMAL TREATMENT ONLY" AND CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE, IF APPLICABLE 
BESEDILO “SAMO ZA ŽIVALI” IN POGOJI ALI OMEJITVE GLEDE OSKRBE IN
In case of accidental oral intake or self-injection, seek medical advice immediately and show the package insert to the physician but DO NOT DRIVE as sedation and changes in blood pressure may occur. 
V primeru nenamernega peroralnega zaužitja ali samoinjiciranja nemudoma poiščite zdravniško pomoč in zdravniku pokažite nalepko na ovojnini, vendar NE VOZITE, saj lahko pride do sedacije in sprememb v krvnem pritisku.
Dexmedetomidine is compatible with butorphanol and ketamine in the same syringe at least for two hours. 
Deksmedetomidin je združljiv z butorfanolom in ketaminom v isti brizgi najmanj dve uri.
Methyl parahydroxybenzoate (E 218) 
metilparahidroksibenzoat (E 218)
Overdose (symptoms, emergency procedures, antidotes) Dogs: 
Preveliko odmerjanje (simptomi, nujni ukrepi, protistrupi) Psi:
In the circulation, dexmedetomidine is largely bound to plasma proteins (>90%). 
Deksmedetomidin se v krvi večinoma veže na plazemske beljakovine (> 90%).
Corneal opacities may occur during sedation (see also the section on Special precautions for the use in animals). 
Med sedacijo lahko pride do motnosti roženice (glejte tudi poglavje Posebni previdnostni ukrepi za uporabo pri živalih).
A slight decrease in temperature may be observed. 
Lahko se pojavi tudi rahlo znižanje telesne temperature.
Atipamezole does not reverse the effect of ketamine. 
Atipamezol ne izniči učinka ketamina.
Due to peripheral vasoconstriction and venous desaturation in the presence of normal arterial oxygenation, the mucous membranes may appear pale and/or with a blue tinge. 
Zaradi periferne vazokonstrikcije in venske desaturacije ob normalni arterijski oksigenaciji so lahko sluznice videti blede in/ali modrikaste.
Use of an appropriately graduated syringe is recommended to ensure accurate dosing when administering small volumes. 
Da bi zagotovili natančno odmerjanje, se pri dajanju majhnih količin priporoča uporaba ustrezno graduirane brizge.
Biotransformations in the cat occur by hydroxylation in the liver. 
Do biološke transformacije pri mačkah pride s hidroksilacijo v jetrih.
Vomiting may occur 5-10 minutes after injection. 
5-10 minut po injiciranju lahko pride do bruhanja.
Anticholinergics should be used with caution with dexmedetomidine. 
Protiholinergične snovi je treba skupaj z deksmedetomidinom uporabljati previdno.
Do not use in case of known hypersensitivity to the active substance or to any of the excipients. 
Ne uporabite v primeru znane preobčutljivosti na zdravilno učinkovino ali katerokoli pomožno snov.
In some dogs and cats, a decrease in respiratory rate may occur. 
Pri nekaterih psih in mačkah se lahko zmanjša hitrost dihanja.
Care should be taken to avoid self-injection. 
Paziti je treba, da ne pride do samoinjiciranja.
People with known hypersensitivity to the active substance or any of the excipients should administer the veterinary medicinal product with caution. 
Osebe z znano preobčutljivostjo na zdravilno učinkovino ali katerokoli pomožno snov morajo zdravilo za uporabo v veterinarski medicini dajati previdno.
Sedation lasts for at least 120 minutes post administration and analgesia lasts for at least 90 minutes. 
Sedacija traja vsaj 120 minut, analgezija pa vsaj 90 minut po dajanju.
Dexmedetomidine is also rapidly distributed in the body and penetrates the blood-brain barrier readily. 
Deksmedetomidin se tudi hitro razširi po telesu in zlahka preide skozi možgansko bariero.
DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION 
ODMERKI ZA POSAMEZNE ŽIVALSKE VRSTE TER POT(I) IN NAČIN UPORABE IN
Administration of atipamezole after dexmedetomidine rapidly reverses the effects and thus shortens the recovery period. 
Uporaba atipamezola po deksmedetomidinu hitro izniči učinke in tako skrajša obdobje okrevanja.
Major biotransformations in the dog include hydroxylation, glucuronic acid conjugation and Nmethylation in the liver. 
Med večje biološke transformacije pri psih spadajo hidroksilacija, konjugacija glukuronske kisline in Nmetilacija v jetrih.
Date of first authorisation:13/12/2016 <Date of last renewal:> <{DD/MM/YYYY}> <{DD month YYYY}.> 
<Datum zadnjega podaljšanja dovoljenja za promet:> <{DD/MM/LLLL}> <{DD mesec LLLL}.>
The dose should be adjusted to the type of surgery, length of procedure and patient temperament. 
Odmerek mora biti prilagojen vrsti in trajanju kirurškega posega ter značaju živali.
Deep sedation and analgesia in dogs in concomitant use with butorphanol for medical and minor surgical procedures. 
Globoka sedacija in analgezija pri psih pri sočasni uporabi z butorfanolom za zdravstvene in manjše kirurške postopke.
Therefore the use of the product during pregnancy and lactation is not recommended. 
Zato uporaba zdravila med brejostjo in dojenjem ni priporočena.
Shelf-life after first opening the container: 56 days. 
EXP: Rok uporabnosti po prvem odpiranju vsebnika: 56 dni.
Dogs: After an intramuscular dose of 50 micrograms/kg a maximum concentration in plasma of about 12 nanograms/ml is reached after 0.6 hours. 
Psi: Po intramuskularnem odmerku v višini 50 mikrogramov/kg je najvišja koncentracija v plazmi približno 12 nanogramov/ml, dosežena po 0,6 ure.
The specific α2-adrenoceptor antagonist, atipamezole, which is approved for use in animals, has been used in humans only experimentally to antagonize dexmedetomidine-induced effects. 
Specifičen antagonist α2-adrenoreceptorjev, odobren za uporabo pri živalih, je bil pri človeku uporabljen kot antagonist učinkov deksmedetomidina samo poskusno.
Volatile anaesthetic requirements for maintenance anaesthesia are also reduced. 
Zmanjšana je tudi potreba po hlapnih anestetikih za vzdrževanje anestezije.
When administering in conjunction with butorphanol (0.1 mg/kg) for deep sedation and analgesia, the intramuscular dose of dexmedetomidine is 300 micrograms/square metre body surface area. 
Pri sočasni uporabi z butorfanolom (0,1 mg/kg) za globoko sedacijo in analgezijo znaša intramuskularni odmerek deksmedetomidina 300 mikrogramov/kvadratni meter telesne površine.
Blood pressure decreases to normal or below normal levels after an initial increase. 
Po začetnem povišanju se krvni pritisk zmanjša na normalno raven ali pod njo.
When dexmedetomidine and ketamine are used sequentially, with a 10 minute interval, cats may occasionally experience AV-block or extrasystole. 
Pri zaporedni uporabi deksmedetomidina in ketamina z 10-minutnim presledkom lahko pri mačkah pride do občasnih AV-blokov ali ekstrasistol.
Dexmedetomidine, butorphanol and/or ketamine can be mixed in the same syringe as they have been shown to be pharmaceutically compatible. 
Deksmedetomidin, butorfanol in/ali ketamin se lahko zmešajo v isti brizgi, saj so dokazano farmacevtsko združljivi.
Muscle tremors may occur during sedation. 
Med sedacijo se lahko pojavi drgetanje mišic.
(mcg/kg) 
(mikrogramov/kg)
Read the package leaflet before use 
Pred uporabo preberite navodilo za uporabo.
Use of dexmedetomidine as a premedicant in dogs and cats significantly reduces the amount of induction medicinal product required for induction of anaesthesia. 
Uporaba deksmedetomidina za premedikacijo psov in mačk bistveno zmanjša količino indukcijskega zdravila, potrebnega za indukcijo anestezije.
Metabolites are excreted mainly in the urine and to a lesser extent in the faeces. 
Presnovki se izločajo večinoma z urinom in v manjši meri z blatom.
Cardboard box pack sizes: 
Velikost pakiranja kartonske škatle:
The premedication dose of dexmedetomidine is 125 - 375 micrograms/square metre body surface area, administered 20 minutes prior to induction for procedures requiring anaesthesia. 
Odmerek deksmedetomidina za premedikacijo je 125-375 mikrogramov/kvadratni meter telesne površine, dati pa ga je treba 20 minut pred začetkom posega, za katerega je anestezija potrebna.
These may include profound sinus bradycardia, 1st and 2nd degree AV block, sinus arrest or pause, as well as atrial, supraventricular and ventricular premature complexes. 
Mednje lahko spadajo globoka sinusna bradikardija, AV-blok prve in druge stopnje, sinusni zastoj ali prekinitev, prav tako prezgodnji atrijski, supraventrikularni in ventrikularni kompleksi.
For the full list of excipients, see section 6.1. 
0,2 mg Za celoten seznam pomožnih snovi, glejte poglavje 6.1.
Premedication in dogs and cats before induction and maintenance of general anaesthesia. 
Premedikacija psov in mačk pred uvajanjem in vzdrževanjem splošne anestezije.
Treated animals should be kept warm and at a constant temperature, both during the procedure and recovery. 
Živalim, zdravljenim s tem zdravilom je treba med posegom in okrevanjem zagotoviti, da so na toplem, pri stalni temperaturi.
A dose of 10 mg ketamine/ kg used concurrently with 40 micrograms dexmedetomidine/ kg may cause tachycardia. 
Uporaba odmerka 10 mg ketamina/kg skupaj s 40 mikrogrami deksmedetomidina/kg lahko povzroči tahikardijo.
All anaesthetic agents used for induction or maintenance of anaesthesia should be administered to effect. 
Vse anestetike za induciranje ali vzdrževanje anestezije je treba dajati,
Concomitant use of dexmedetomidine and butorphanol produces sedative and analgesic effects beginning no later than 15 minutes after administration. 
Sočasna uporaba deksmedetomidina in butorfanola sproži sedativne in analgetične učinke v manj kot 15 minutah po dajanju.
By virtue of its α2-adrenergic activity, dexmedetomidine causes a decrease in heart rate and body temperature. 
Deksmedetomidin zaradi α2-adrenergičnega delovanja povzroča zmanjšanje srčnega utripa in telesne temperature.
The use of other central nervous system depressants is expected to potentiate the effects of dexmedetomidine and therefore an appropriate dose adjustment should be made. 
Pričakuje se, da uporaba drugih zaviralcev osrednjega živčevja okrepi učinke deksmedetomidina, zato je potrebna ustrezna prilagoditev odmerka.
Pregnant women should administer the product with special caution to avoid self-injection since uterine contractions and decreased foetal blood pressure may occur after accidental systemic exposure. 
Nosečnice morajo pri injiciranju zdravila še posebno paziti, da ne pride do samoinjiciranja, saj lahko po nenamerni sistemski izpostavitvi pride do krčev maternice in zmanjšanega krvnega tlaka pri plodu.
Methyl parahydroxybenzoate (E 218) Propyl parahydroxybenzoate Sodium chloride 
Metilparahidroksibenzoat (E 218) Propilparahidroksibenzoat Natrijev klorid
Advice to physicians: Cepedex is an α2-adrenoreceptor agonist, symptoms after absorption may involve clinical effects including dose-dependent sedation, respiratory depression, bradycardia, hypotension, a dry mouth, and hyperglycaemia. 
Nasvet zdravnikom: zdravilo Cepedex je agonist α2-adrenoreceptorjev, simptomi po absorpciji lahko vključujejo klinične učinke, vključno s sedacijo odvisno od odmerka, respiratorno depresijo, bradikardijo, hipotenzijo, suhimi usti in hiperglikemijo.
If you notice any serious effects or other effects not mentioned in this package leaflet, please inform your veterinary surgeon. 
Če opazite kakršne koli resne neželene učinke ali druge učinke, ki niso omenjeni v teh navodilih za uporabo,
Vomiting, hypothermia and nervousness have been reported after such use. 
Po taki uporabi so poročali o bruhanju, podhladitvi in živčnosti.
The apparent volume of distribution (Vd) is 2.2 l/kg and the elimination half-life (t1⁄2) is one hour. 
Navidezni volumen porazdelitve (Vd) je 2,2 l/kg, razpolovni čas izločanja (t1⁄2) pa ena ura.
Sedation may be reversed with atipamezole (see section 4.10). 
Učinki sedacije se lahko izničijo z atipamezolom (glejte poglavje 4.10).