natgillin/translations-raw huggingface dataset:
For more information about treatment with Clopidogrel Zentiva, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist. 
Za več informacij o zdravljenju z zdravilom Clopidogrel Zentiva preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte s svojim zdravnikom ali farmacevtom.
• recently had a myocardial infarction (heart attack). 
• ki so nedavno doživeli miokardni infarkt (srčni napad).
• peripheral arterial disease (problems with blood flow in the arteries); 
• ki imajo periferno arterijsko bolezen (težave s pretokom krvi v arterijah);
The European Commission granted a marketing authorisation valid throughout the European Union for Clopidogrel Winthrop on 16 July 2008. 
Evropska komisija je dovoljenje za promet z zdravilom Clopidogrel Zentiva , veljavno po vsej Evropski uniji, odobrila dne 16. julija 2008.
This showed that Clopidogrel Zentiva reduces the risk of an event. 
To je dokaz, da zdravilo Clopidogrel Zentiva zmanjšuje tveganje za pojav dogodka.
This is a summary of the European public assessment report (EPAR) for Clopidogrel Zentiva. 
Ta dokument je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Clopidogrel Zentiva.
The standard dose of Clopidogrel Zentiva is one 75-mg tablet once a day. 
Običajni odmerek zdravila Clopidogrel Zentiva je ena 75-miligramska tableta enkrat dnevno.
Clopidogrel Zentiva should not be used in people who may be hypersensitive (allergic) to clopidogrel or any of the other ingredients. 
Zdravila Clopidogrel Zentiva ne smejo uporabljati osebe, ki utegnejo biti preobčutljive za (alergične na) klopidogrel ali katero koli drugo sestavino zdravila.
In CAPRIE, there were 939 events in the Clopidogrel Zentiva group, and 1,020 in the aspirin group. 
V študiji CAPRIE je bilo v skupini, ki je prejemala zdravilo Clopidogrel Zentiva, 939 dogodkov, v skupini, zdravljeni z aspirinom, pa 1 020.
Clopidogrel Zentiva can be started between a few days and 35 days after the attack; 
Zdravilo Clopidogrel Zentiva se lahko začne jemati od nekaj dni po napadu do 35 dni po njem;
Clopidogrel Zentiva is converted into its active form in the body. 
Zdravilo Clopidogrel Zentiva se v svojo aktivno obliko pretvori v telesu.
In acute coronary syndrome and atrial fibrillation, Clopidogrel Zentiva is used together with aspirin, the dose of which should not be higher than 100 mg. 
Pri akutnem koronarnem sindromu in atrijski fibrilaciji se zdravilo Clopidogrel Zentiva uporablja skupaj z aspirinom, katerega odmerek ne sme biti višji od 100 mg.
Some of these patients have had a stent inserted (a short tube) placed in an artery to prevent it from closing up. 
Nekaterim bolnikom je bil v arterijo vstavljen stent (kratka cevka), da prepreči njeno zamašitev.
In acute coronary syndrome, treatment generally starts with a loading dose of one 300-mg tablet or four 75-mg tablets. 
Pri akutnem koronarnem sindromu se zdravljenje na splošno začne z udarnim odmerkom ene 300miligramske tablete ali štirih 75-miligramskih tablet.
The most common side effects with Clopidogrel Zentiva (seen in between 1 and 10 patients in 100) are haematoma (a collection of blood under the skin), epistaxis (nosebleeds), gastrointestinal haemorrhage (bleeding in the stomach or gut), diarrhoea, abdominal pain (stomach ache), dyspepsia (heartburn), bruising and bleeding where the skin is punctured. 
Najpogostejši neželeni učinki zdravila Clopidogrel Zentiva (opaženi pri 1 do 10 bolnikih izmed 100) so hematomi (kopičenje krvi pod kožo), epistaksa (krvavitve iz nosu), gastrointestinalna hemoragija (krvavitve v želodcu ali črevesju), driska, bolečine v trebuhu, dispepsija (zgaga), podplutbe in krvavitve na mestu, kjer je koža predrta.
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Clopidogrel Zentiva. 
Pojasnjuje, kako je Odbor za zdravila za uporabo v humani medicini (CHMP) ocenil zdravilo Clopidogrel Zentiva, na podlagi česar je oblikoval mnenje za odobritev dovoljenja za promet z njim in priporočila glede pogojev njegove uporabe.
Clopidogrel Zentiva was more effective than aspirin at preventing new ischaemic events. 
Zdravilo Clopidogrel Zentiva je bilo pri preprečevanju novih ishemičnih dogodkov učinkovitejše od aspirina.
The main measure of effectiveness was how many patients experienced a new ‘ischaemic event' (heart attack, ischaemic stroke or death) over one to three years. 
Glavno merilo učinkovitosti je bilo, koliko bolnikov je v enem do treh let utrpelo nov „ishemični dogodek“ (srčni napad, ishemično kap ali smrt).
In the studies of acute coronary syndrome, all of the patients also took aspirin and the main measure of effectiveness was the number of patients who experienced an ‘event' such as a blocked artery, another heart attack or death during the study. 
V študijah akutnega koronarnega sindroma so vsi bolniki jemali tudi aspirin, glavno merilo učinkovitosti pa je bilo število bolnikov z „dogodkom“, kot je blokirana arterija, ponovni srčni napad ali smrt med študijo.
Clopidogrel Zentiva can be started between seven days and six months after the stroke; 
Zdravilo Clopidogrel Zentiva se lahko začne jemati od sedem dni po napadu do šest mesecev po njem;
The CHMP decided that Clopidogrel Zentiva's benefits are greater than its risks and recommended that it be given marketing authorisation. 
Odbor za zdravila za uporabo v humani medicini (CHMP) je zaključil, da so koristi zdravila Clopidogrel Zentiva večje od z njim povezanih tveganj, in priporočil, da se zanj odobri dovoljenje za promet.
Clopidogrel Zentiva is used to prevent problems caused by blood clots in adults who have: 
Zdravilo Clopidogrel Zentiva se uporablja za preprečevanje težav, ki jih povzročajo krvni strdki pri odraslih,
Clopidogrel Zentiva is a medicine that contains the active substance clopidogrel. 
Clopidogrel Zentiva je zdravilo, ki vsebuje zdravilno učinkovino klopidogrel.
In the study in atrial fibrillation patients, Clopidogrel Zentiva taken together with aspirin reduced the risk of new events by 11% compared with placebo taken with aspirin, with the largest reduction (28%) seen for stroke. 
V študiji atrijske fibrilacije so bolniki zdravilo Clopidogrel Zentiva jemali skupaj z aspirinom, kar je zmanjšalo tveganje za nove dogodke za 11 % v primerjavi s placebom, vzetim skupaj z aspirinom, kjer je bilo največje zmanjšanje, opaženo pri kapi (28 %).
• atrial fibrillation (irregular rapid contractions of the upper chambers of the heart), when it should be given with aspirin. 
• ki trpijo za atrijsko fibrilacijo (nerednim hitrim krčenjem zgornjih srčnih preddvorov), pri katerih se mora dajati skupaj z aspirinom.
What benefit has Clopidogrel Zentiva shown during the studies? 
Kakšne koristi je zdravilo Clopidogrel Zentiva izkazalo med študijami?
For the full list of all side effects reported with Clopidogrel Zentiva, see the Package Leaflet. 
Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila Clopidogrel Zentiva, glejte navodilo za uporabo.
• recently had an ischaemic stroke (stroke caused by failure of the blood supply to part of the brain). 
• ki so nedavno utrpeli ishemično kap (kap zaradi neoskrbe določenega dela možganov s krvjo).
Previously known as Clopidogrel Winthrop events such as a heart attack or stroke, cannot take vitamin K antagonists (other medicines that prevent blood clots) and are at low risk of bleeding. 
pri katerih obstaja vsaj en dejavnik tveganja za vaskularni dogodek, kot je srčni napad ali kap, ki ne morejo jemati antagonistov vitamina K (drugega zdravila, ki preprečuje krvne strdke) in pri katerih obstaja majhno tveganje za krvavitve.
Clopidogrel Zentiva has been compared with aspirin in a study called CAPRIE including around 19,000 patients who had recently had a heart attack or ischaemic stroke, or who had established peripheral arterial disease. 
Zdravilo Clopidogrel Zentiva so primerjali z aspirinom v študiji CAPRIE, v katero je bilo vključenih okoli 19 000 bolnikov, ki so nedavno doživeli srčni napad ali ishemično kap ali pri katerih je bilo ugotovljeno periferno arterijsko obolenje.
• a condition known as ‘acute coronary syndrome', when it should be given with aspirin (another medicine that prevents blood clots). 
• ki imajo akutni koronarni sindrom, pri katerem se mora zdravilo dajati skupaj z aspirinom (drugim zdravilom za preprečevanje krvnih strdkov).
In ST segment elevation myocardial infarction, fewer patients on Clopidogrel Zentiva had events than patients on placebo (262 against 377 in the CLARITY study, and 2,121 against 2,310 in the COMMIT study). 
Pri miokardnem infarktu z dvigom spojnice ST je dogodke utrpelo manj bolnikov, ki so jemali zdravilo Clopidogrel Zentiva, od tistih, ki so jemali placebo (262 oziroma 377 v študiji CLARITY in 2 121 oziroma 2 310 v študiji COMMIT).
Clopidogrel Zentiva has also been compared with placebo in two studies involving patients with ST segment elevation: CLARITY, which involved over 3,000 patients and lasted for up to eight days; and COMMIT, which involved almost 46,000 patients and in which the patients received Clopidogrel Zentiva with or without metoprolol (another medicine used for heart problems or high blood pressure) for up to four weeks. 
Zdravilo Clopidogrel Zentiva so primerjali tudi s placebom v dveh študijah z bolniki z elevacijo ST-spojnice: študija CLARITY je vključevala več kot 3 000 bolnikov in je trajala do osem dni, študija COMMIT pa je vključevala skoraj 46 000 bolnikov, ki so do štiri tedne prejemali zdravilo Clopidogrel Zentiva z metoprololom (drugim zdravilom za težave s srcem ali visok krvni tlak) ali brez njega.
The active substance in Clopidogrel Zentiva, clopidogrel, is an inhibitor of platelet aggregation. 
Zdravilna učinkovina v zdravilu Clopidogrel Zentiva, klopidogrel, je zaviralec agregacije trombocitov.
In acute coronary syndrome, Clopidogrel Zentiva has been compared with placebo (a dummy treatment) in one study involving over 12,000 patients with non-ST segment elevation, 2,172 of whom had a stent inserted during the study (CURE study, lasting up to a year). 
Pri akutnem koronarnem sindromu so zdravilo Clopidogrel Zentiva primerjali s placebom (zdravilom brez zdravilne učinkovine) v eni študiji z 12 000 bolniki brez dviga spojnice ST, od katerih so 2 172 bolnikom med študijo vstavili stent (študija CURE, ki je trajala do enega leta).
What is the risk associated with Clopidogrel Zentiva? 
Kakšna tveganja so povezana z zdravilom Clopidogrel Zentiva?
Why has Clopidogrel Zentiva been approved? 
Zakaj je bilo zdravilo Clopidogrel Zentiva odobreno?
Other information about Clopidogrel Zentiva 
Druge informacije o zdravilu Clopidogrel Zentiva:
In other words, about 10 patients in 1,000 will avoid having a new ischaemic event two years after starting Clopidogrel Zentiva instead of aspirin. 
To pomeni, da bo med bolniki, ki jemljejo zdravilo Clopidogrel Zentiva, manj novih ishemičnih napadov kot pri tistih, ki jemljejo aspirin, saj jemanje zdravila Clopidogrel Zentiva namesto aspirina prepreči ponovni ishemični napad v dveh letih po začetku jemanja pri približno 10 bolnikih od 1 000.
In atrial fibrillation, Clopidogrel Zentiva has been compared with placebo (both taken together with aspirin) in one main study involving around 7,500 patients who had at least one risk factor for vascular events and who could not take vitamin K antagonist therapy. 
Pri atrijski fibrilaciji je bilo zdravilo Clopidogrel Zentiva primerjano s placebom (oba vzeta skupaj z aspirinom) v eni glavni študiji, v kateri je sodelovalo okoli 7 500 bolnikov, ki so imeli vsaj en dejavnik tveganja za vaskularni dogodek in ki ne morejo prejemati zdravljenja z antagonistom vitamina K. Bolniki so bili zdravljeni povprečno tri leta, glavno merilo učinkovitosti pa je bilo število bolnikov, ki so doživeli bodisi srčni napad bodisi ishemično kap ali pa so umrli.
How has Clopidogrel Zentiva been studied? 
Kako je bilo zdravilo Clopidogrel Zentiva raziskano?
What is Clopidogrel Zentiva? 
Kaj je zdravilo Clopidogrel Zentiva?
What is Clopidogrel Zentiva used for? 
Za kaj se zdravilo Clopidogrel Zentiva uporablja?
How is Clopidogrel Zentiva used? 
Kako se zdravilo Clopidogrel Zentiva uporablja?
How does Clopidogrel Zentiva work? 
Kako zdravilo Clopidogrel Zentiva deluje?
6 (6 x 1) pre-filled pens + 6 (6 x 1) swab (multipack) 
6(6x1) napolnjenih injekcijskih peresnikov + 6(6x1) blazinic (skupno pakiranje)
• Be careful how much alcohol you drink. 
• Bodite pozorni na to, koliko alkohola popijete.
If this happens, a more specific test can be performed. 
Če se to zgodi, se morajo uporabiti bolj specifične preiskave.
The mechanism for this increased risk is not known. 
Mehanizem tega povečanega tveganja ni znan.
The patients in these trials died from a variety of causes that were consistent with expectations for this population. 
Bolniki v teh preskušanjih so umrli zaradi različnih vzrokov, ki so se skladali s pričakovanji za to populacijo.
Long-term implications for cognitive and behavioural development are not known. 
Dolgoročne posledice za kognitivni in vedenjski razvoj niso znane.
The product information may be subsequently updated by the Member State competent authorities, in liaison with the Reference Member State, as appropriate, in accordance with the procedures laid down in Chapter 4 of Title III of Directive 2001/83/EC. 
Informacije o zdravilu se lahko nato posodobijo s strani pristojnih organov držav članic v sodelovanju z referenčno državo članico, kot je to primerno, skladno s postopki, določenimi v Poglavju 4 Naslova III Direktive 2001/83/EC.
Tell your doctor as soon as possible if you have: 
Svojemu zdravniku morate čim prej povedati, če imate:
The relevance of this finding for humans is unknown. 
Pomen te ugotovitve za človeka ni znan.
However, some cases occurred in patients without pre-existing risk factors. 
Vendar pa so se nekateri primeri pojavili tudi pri bolnikih brez obstoječih dejavnikov tveganja.
Consequently, newborns should be monitored carefully. 
Zato je treba novorojenčke skrbno spremljati.
This risk persists until significant remission occurs. 
Takšno tveganje obstaja, vse dokler ne pride do znatnega umika bolezni.
The average dose was 669 mg. 
Povprečni odmerek je bil 669 mg.
You and your doctor should check your weight regularly. 
Vi sami in vaš zdravnik morate redno kontrolirati vašo telesno maso.
(16) May lead to falls. 
(16) Lahko povzroči padce.
(12) See text below 
(12) Glejte besedilo spodaj.
You might ask them to tell you if they think your depression is getting worse, or if they are worried about changes in your behaviour. 
Prosite ga lahko tudi, da naj vas opozori, če meni, da se je depresija poslabšala ali ga skrbijo spremembe v vašem vedenju.
Decreases in free T3 
znižanje prostega T3
This belongs to a group of medicines called antipsychotics. 
Spada v skupino zdravil, ki jih imenujemo antipsihotiki.
Gradual withdrawal over a period of at least 1 to 2 weeks is advisable. 
Priporočljiva je postopna opustitev v obdobju vsaj 1 do 2 tednov.
Two short-term (6 week) studies enrolled patients who had shown an inadequate response to at least one antidepressant. 
Dve kratkotrajni (6-tedenski) študiji sta vključili bolnike, ki so se neustrezno odzvali na vsaj en antidepresiv.
• Disturbance in speech and language. 
• motnje pri govoru, jeziku,
These thoughts may also be increased if you suddenly stop taking your medication. 
Takšne misli lahko postanejo hujše, če nenadno prenehate z jemanjem vašega zdravila.
In some cases, a prior increase in body weight has been reported which may be a predisposing factor. 
V nekaterih primerih so ugotovili predhodno povečanje telesne mase, kar bi lahko bil predispozicijski dejavnik.
• Change in electrical activity of the heart seen on ECG (QT prolongation) 
• sprememba v električni aktivnosti srca, ki se vidi na EKG (podaljšanje intervala QT),
It must therefore be ensured that patients receive clear information on the appropriate dosage for their condition. 
Zato je treba zagotoviti, da bolniki dobijo jasne informacije o ustreznem odmerjanju za njihovo bolezen.
You may be more likely to think like this if you are a young adult. 
Pojav takšnih misli se vam verjetneje pojavi, če ste mladi odrasli.
• You will take your tablets once a day, at bedtime or twice a day, depending on your illness 
• Tablete boste jemali enkrat na dan pred spanjem ali dvakrat na dan, odvisno od vaše bolezni.
Close medical supervision and monitoring should be continued until the patient recovers. 
Natančen zdravniški nadzor in spremljanje sta potrebna, dokler si bolnik ne opomore.
• You have problems with your liver. 
• imate težave z jetri,
If your baby develops any of these symptoms you may need to contact your doctor. 
Če vaš otrok razvije katerega koli od teh simptomov, se boste morda morali posvetovati s svojim zdravnikom.
It is general clinical experience that the risk of suicide may increase in the early stages of recovery. 
Splošne klinične izkušnje kažejo, da se tveganje za samomor v zgodnji fazi izboljšanja lahko poveča.
• You or someone else in your family has a history of blood clots, as medicines like these have been associated with formation of blood clots. 
• imate vi ali kdo v vaši družini zgodovino nastanka krvnih strdkov, saj so ta zdravila povezana z nastankom krvnih strdkov.
The moderate amount of published data from exposed pregnancies (i.e. between 300-1000 pregnancy outcomes), including individual reports and some observational studies do not suggest an increased risk of malformations due to treatment. 
Zmeren obseg objavljenih podatkov o izpostavljenih nosečnostih (med 300-1000 izidov nosečnosti), vključno s posameznimi poročili in nekaj opazovalnimi študijami, ne kaže povečanega tveganja za pojav malformacij zaradi zdravljenja.
There was no apparent dose relationship. 
Očitne povezanosti z odmerkom ni bilo.
Therefore, quetiapine should only be used during pregnancy if the benefits justify the potential risks. 
Kvetiapin se sme zato uporabljati med nosečnostjo le, če koristi zdravljenja upravičujejo možna tveganja.
No data are available on maintenance of effect or recurrence prevention in this age group. 
Podatkov o vzdrževanju učinka ali preprečevanju ponovitve za to starostno skupino ni.
Appropriate clinical monitoring is advisable in accordance with utilised antipsychotic guidelines. 
Priporočljivo je ustrezno klinično spremljanje v skladu z uporabljanimi smernicami za antipsihotike.
This is not recommended as standard treatment, because of potential negative effect of physostigmine on cardiac conductance. 
To ni priporočljivo kot standardno zdravljenje in sicer zaradi potencialnega negativnega učinka fizostigmina na prevodnost srca.
• Dizziness or a severe sense of feeling sleepy. 
• omotica ali občutek hude zaspanosti.
Formal interaction studies with commonly used cardiovascular medicinal products have not been performed. 
Formalne študije medsebojnega delovanja s pogosto uporabljanimi srčno-žilnimi zdravili niso bile izvedene.
Your doctor may suggest you reduce the dose gradually before stopping treatment. 
Zdravnik vam bo morda svetoval, da pred opustitvijo zdravila odmerek zmanjšujete postopoma.
An increased risk cannot be excluded for other antipsychotics or other patient populations. 
Večjega tveganja ni mogoče izključiti za druga antipsihotična zdravila ali druge populacije bolnikov.
• You have had a stroke, especially if you are elderly 
• ste imeli možgansko kap, zlasti če ste starejši,
The available evidence from placebo-controlled clinical trials is presented in sections 4.4, 4.8, 5.1 and 5.2. 
Ugotovitve s placebom kontroliranih kliničnih preskušanj so predstavljene v poglavjih 4.4, 4.8, 5.1 in 5.2.
Your doctor may ask you to have blood tests from time to time. 
Zdravnik vas bo zato morda občasno napotil na preiskavo krvi.
Lipid changes should be managed as clinically appropriate. 
Spremembe lipidov naj bodo zdravljene, kot je klinično primerno.
These conditions can be caused by this type of medicine. 
Te znake lahko povzroči ta skupina zdravil.
Efficacy and safety has not been evaluated in patients over 65 years with depressive episodes in the framework of bipolar disorder. 
Učinkovitost in varnost nista ocenjeni pri bolnikih, starejših od 65 let, z depresivnimi epizodami v okviru bipolarne motnje.
Approximately 73% of the radioactivity is excreted in the urine and 21% in the faeces. 
Približno 73 % radioaktivnosti se izloči v urinu in 21 % v blatu.
For these patients, the mean maximum decrease in hemoglobin at any time was -1.50 g/dL. 
Pri teh bolnikih, je bilo povprečno največje znižanje hemoglobina kadarkoli -1,50 g/dl.
• Some medicines for HIV. 
• nekatera zdravila za zdravljenje HIV,
• Feeling more hungry 
• občutek večje lakote,
Some side effects are only seen when a blood test is taken. 
Nekateri neželeni učinki se lahko odkrijejo le s preiskavo krvi.
This Summary of Product Characteristics, labelling and package leaflet is the outcome of the referral procedure to which this Commission decision relates. 
Ta Povzetek glavnih značilnosti zdravila, Ovojnina in Navodilo za uporabo so rezultat napotitvenega postopka, s katerim je povezana odločitev Komisije.
The recommended daily dose is 300 mg. 
Priporočeni dnevni odmerek je 300 mg.
Therefore, patients should be advised to exercise caution until they are familiar with the potential effects of the medication. 
Zato je treba bolnikom naročiti, naj bodo previdni, dokler ne spoznajo možnih učinkov zdravila.
Contact your doctor or nearest hospital straight away. 
Takoj pojdite do svojega zdravnika ali v najbližjo bolnišnico.
• Increased appetite 
• povečan apetit,
In patients who develop these symptoms, increasing the dose may be detrimental. 
Bolnikom, ki se jim pojavijo ti simptomi, lahko povečanje odmerka škoduje.
There is no specific antidote to quetiapine. 
Specifičnega antidota za kvetiapin ni.
• Schizophrenia: where you may hear or feel things that are not there, believe things that are not true or feel unusually suspicious, anxious, confused, guilty, tense or depressed. 
• shizofrenije: ko lahko slišite ali zaznavate stvari, ki jih ni, verjamete v stvari, ki niso resnične ali se počutite nenavadno sumničave, zaskrbljene, zmedene, krive, napete ali depresivne.
You may find it helpful to tell a relative or close friend that you are depressed, and ask them to read this leaflet. 
Morda bi bilo koristno, če za težave z depresijo poveste sorodniku ali dobremu prijatelju, in ga prosite, da prebere to navodilo.
The maintenance dose (daily dose) will depend on your illness and needs but will usually be between 150 mg and 800 mg. 
Vzdrževalni odmerek (dnevni odmerek) bo odvisen od vaše bolezni in potreb, a praviloma je odmerek med 150 mg in 800 mg.
All prolonged-release tablets are capsule shaped and marked with XR and the strength. 
Vse tablete s podaljšanim sproščanjem so kapsulaste oblike in označene z oznako »XR« in jakostjo.
There are no data from long-term studies to demonstrate Seroquel's effectiveness in preventing subsequent manic or depressive episodes. 
Ni podatkov iz dolgotrajnih študij, ki bi pokazali učinkovitost zdravila Seroquel pri preprečevanju poznejših maničnih ali depresivnih epizod.
Individual patients may benefit from a 600 mg dose. 
Posameznim bolnikom lahko koristi odmerek 600 mg.
• You can take your tablets with or without food. 
• Tablete lahko jemljete s hrano ali brez.
In laboratory animals at a clinically relevant exposure level the following deviations were seen, which as yet have not been confirmed in long-term clinical research: 
Pri laboratorijskih živalih so ob klinično pomembni ravni izpostavljenosti opažali naslednje odklone, ki pa v dolgoročnih kliničnih raziskavah doslej še niso bili potrjeni:
If you notice any of these symptoms seek medical advice immediately. 
Če opazite katerega od teh simptomov nemudoma poiščite zdravniško pomoč.
As improvement may not occur during the first few weeks or more of treatment, patients should be closely monitored until such improvement occurs. 
Ker se prvih nekaj tednov zdravljenja ali dlje zdravstveno stanje morda še ne bo izboljšalo, je potrebno bolnike skrbno nadzirati, vse dokler ne pride do izboljšanja.