natgillin/translations-raw huggingface dataset:
What was EnCyzix expected to be used for? 
Za kaj naj bi se zdravilo EnCyzix uporabljalo?
Patients were given either EnCyzix, or placebo (a dummy treatment) with and without application of a testosterone gel. 
Bolniki so prejemali zdravilo EnCyzix ali placebo (zdravilo brez zdravilne učinkovine).
The main measures of effectiveness were the amount of sperm produced and testosterone levels. 
Pri tem so nekateri uporabljali gel s testosteronom in drugi ne. Glavni merili učinkovitosti sta bili količina nastale sperme in raven testosterona.
The results of the two measurements were compared to see if they were in agreement. 
Dobljene rezultate obeh meritev so primerjali, da bi ugotovili, ali se ujemajo.
Following this, 51 of the patients went on to be followed up for an average of three and a half more years. 
Potem so 51 bolnikov spremljali še v povprečju tri leta in pol.
The European Commission granted a marketing authorisation valid throughout the European Union for Thyrogen on 9 March 2000. 
Evropska komisija je dovoljenje za promet z zdravilom Thyrogen, veljavno po vsej Evropski uniji, odobrila dne 9. marca 2000.
Thyrogen must not be used during pregnancy. 
Zdravilo Thyrogen se ne sme uporabljati med nosečnostjo.
The full EPAR for Thyrogen can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports. 
Celotno evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Thyrogen je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European public assessment reports.
This is a summary of the European public assessment report (EPAR) for Thyrogen. 
To je povzetek evropskega javnega poročila o oceni zdravila (EPAR) za zdravilo Thyrogen.
This finding was confirmed in the follow-up study: all 43 patients whose results could be evaluated after a further three and a half years had successful treatment. 
To odkritje je potrdila študija spremljanja bolnikov: pri vseh 43 bolnikih, pri katerih je bilo rezultate mogoče vrednotiti po treh letih in pol, je bilo zdravljenje uspešno.
Thyrogen thyrotropin alfa 
Thyrogen tirotropin alfa
For more information about treatment with Thyrogen, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist. 
Za več informacij o zdravljenju z zdravilom Thyrogen preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte z zdravnikom ali farmacevtom
The CHMP decided that Thyrogen's benefits are greater than its risks and recommended that it be given marketing authorisation. 
Odbor CHMP je zaključil, da so koristi zdravila Thyrogen večje od z njim povezanih tveganj, in priporočil, da se zanj odobri dovoljenje za promet.
What benefit has Thyrogen shown during the studies? 
Kakšne koristi je zdravilo Thyrogen izkazalo med študijami?
The most common side effect with Thyrogen (seen in more than 1 patient in 10) is nausea (feeling sick). 
Najpogostejši neželeni učinek zdravila Thyrogen (opažen pri 1 bolniku od 10) je navzeja (slabost).
This included 25 patients using Thyrogen and 18 whose replacement therapy was stopped. 
V to skupino spada 25 bolnikov, ki so uporabili zdravilo Thyrogen, in 18 bolnikov s prekinitvijo nadomestnega zdravljenja.
Thyrotropin alfa is produced by a method known as ‘recombinant DNA technology': it is made by a cell that has received a gene (DNA), which makes the cell able to produce the hormone. 
Tirotropin alfa proizvajajo z metodo, imenovano „tehnologija rekombinantne DNK“, pri kateri celica prejme gen (DNK), s katerim lahko tvori hormon.
For eliminating remaining thyroid tissue following thyroid cancer surgery, both treatments were 100% successful after eight months. 
Pri odstranjevanju preostalega ščitničnega tkiva po operaciji ščitnice zaradi raka sta bila po osmih mesecih oba načina zdravljenja 100 % uspešna.
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Thyrogen. 
Pojasnjuje, kako je Odbor za zdravila za uporabo v humani medicini (CHMP) ocenil zdravilo Thyrogen, na podlagi česar je oblikoval mnenje za odobritev dovoljenja za promet z njim in priporočila glede pogojev njegove uporabe.
The iodine is given 24 hours after the last Thyrogen injection and scan is performed 48 to 72 hours later. 
Jod je treba dati 24 ur po zadnji injekciji zdravila Thyrogen, slikanje pa se izvede 48 do 72 ur kasneje.
Thyrogen should not be used in people who may be hypersensitive (allergic) to bovine (cow) or human TSH or to any of the other ingredients. 
Zdravila Thyrogen ne smejo uporabljati osebe, ki utegnejo biti preobčutljive za (alergične na) ščitnico stimulirajoči hormon govejega ali človeškega izvora ali katero koli drugo sestavino zdravila.
In these cases, a scan will be carried out a few days later to see if there is any more thyroid tissue left. 
V takšnih primerih se slikanje izvede z zamikom nekaj dni, ko se preveri, ali je ostalo še kaj ščitničnega tkiva.
However, Thyrogen has the advantage of allowing patients to remain on their replacement therapy before the test is carried out, resulting in a better quality of life, as the temporary withdrawal of the replacement therapy has transient sideeffects which cannot always be tolerated easily. 
Prednost zdravila Thyrogen pa je v tem, da bolnikom omogoča, da pred izvedbo testa še vedno prejemajo nadomestno zdravljenje, kar jim zagotavlja boljšo kakovost življenja, saj ima začasna prekinitev nadomestnega zdravljenja prehodne neželene učinke, ki jih bolniki včasih težko prenašajo.
Other information about Thyrogen 
Druge informacije o zdravilu Thyrogen:
The use of Thyrogen should be supervised by a doctor with expertise in thyroid cancer. 
Uporabo zdravila Thyrogen mora nadzorovati zdravnik z izkušnjami na področju raka ščitnice.
Seventy-two hours after the last injection, a blood test is carried out to check for the presence of a thyroid protein called thyroglobulin, which indicates the presence of thyroid tissue. 
72 ur po zadnjem injiciranju je treba opraviti krvno preiskavo, s katero se preveri prisotnost beljakovine ščitnice, imenovane tiroglobulin, ki nakazuje prisotnost ščitničnega tkiva.
To do this, measurements of thyroid stimulation (production of thyroglobulin and uptake of radioactive iodine) were taken twice: once after treatment with Thyrogen and once after the patients had stopped taking the replacement therapy that inhibits their natural TSH production. 
V ta namen so meritve stimulacije ščitnice (proizvodnja tiroglobulina in privzem radioaktivnega joda) opravili dvakrat: enkrat po zdravljenju z zdravilom Thyrogen in enkrat, ko so bolniki prenehali prejemati nadomestno zdravljenje, ki onemogoča nastajanje naravnega hormona TSH.
Thyrogen is a powder that is made up into a solution for injection. 
Zdravilo Thyrogen je prašek za pripravo raztopine za injiciranje.
What is the risk associated with Thyrogen? 
Kakšna tveganja so povezana z zdravilom Thyrogen?
The active substance in Thyrogen, thyrotropin alfa, is a copy of TSH and is used to stimulate any remaining thyroid tissue in the body, including cancerous tissue. 
Zdravilna učinkovina v zdravilu Thyrogen, tirotropin alfa, je kopija TSH in se uporablja za spodbujanje morebitnega preostalega ščitničnega tkiva v telesu, vključno z rakavimi tkivi.
The company also presented the results of studies from the published literature looking at Thyrogen's effect when it was used with a thyroglobulin test, but without a radioactive iodine scan. 
Družba je predstavila tudi rezultate študij iz objavljene literature, v katerih so proučevali učinek zdravila Thyrogen pri uporabi s tiroglobulinskim testom, vendar brez slikanja z radioaktivnim jodom.
Thyrogen used with lower doses of radioactive iodine was also shown to be effective. 
Tudi ko so zdravilo Thyrogen uporabili z nižjimi odmerki radioaktivnega joda, se je izkazalo za učinkovito.
Thyrogen can also be used in combination with radioactive iodine to ablate (eliminate) any remaining thyroid tissue in patients who have had all or almost all of their thyroid gland removed and whose cancer has not spread to other parts of the body. 
Zdravilo Thyrogen se lahko uporablja tudi v kombinaciji z radioaktivnim jodom za odstranjevanje (uničevanje) preostalega ščitničnega tkiva pri bolnikih, ki so jim odstranili celo ali skoraj celo ščitnico in pri katerih se rak ni razširil na druge dele telesa.
The published studies showed that using Thyrogen was also effective in low-risk patients when leftover tissue was detected only by measuring thyroglobulin levels and that it was not always necessary to do a radioactive iodine scan. 
Objavljene študije so pokazale, da je bila uporaba zdravila Thyrogen učinkovita tudi pri bolnikih z majhnim tveganjem, ko so odkrili ostanke tkiva samo z merjenjem ravni tiroglobulina in slikanje z radioaktivnim jodom ni bilo vedno potrebno.
This is because Thyrogen will stimulate the cells in the tissue to take up the radioactive iodine, which then eliminates them. 
Zdravilo namreč spodbuja celice v tkivu, da privzamejo radioaktivni jod, ki nato te celice uniči.
It is given as two injections into the buttock muscle, 24 hours apart. 
Zdravilo se daje v obliki dveh injekcij v zadnjično mišico v razmiku 24 ur.
For thyroid tissue to be detected, it needs to be active, and this requires the presence of a hormone called thyroid stimulating hormone (TSH). 
Da lahko zaznamo tkivo ščitnice, ga moramo najprej aktivirati, za kar mora biti prisoten hormon, ki ga imenujemo ščitnico stimulirajoči hormon (TSH).
It contains the active substance thyrotropin alfa. 
Vsebuje zdravilno učinkovino tirotropin alfa.
For the full list of all side effects reported with Thyrogen, see the package leaflet. 
Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila Thyrogen, glejte navodilo za uporabo.
The main measure of effectiveness was based on a test to see if the patient had any thyroid tissue remaining at eight months after treatment. 
Glavno merilo učinkovitosti je temeljilo na kontroli osem mesecev po zdravljenju, pri kateri so ugotavljali, ali so pri bolniku še prisotni ostanki ščitničnega tkiva.
When Thyrogen is used to eliminate left-over thyroid tissue, radioactive iodine is also given 24 hours after the last Thyrogen injection. 
Ko se zdravilo Thyrogen uporablja za odstranjevanje preostalega ščitničnega tkiva, je treba radioaktivni jod ravno tako dati 24 ur po zadnji injekciji zdravila Thyrogen.
The thyroglobulin test is an alternative to the radioactive iodine scan for detecting remaining thyroid tissue which involves measuring thyroglobulin produced by the thyroid tissue in the blood. 
Tiroglobulinski test je alternativna metoda slikanju z radioaktivnim jodom za zaznavo preostalega ščitničnega tkiva, ki vključuje meritve tiroglobulina, ki ga proizvaja ščitnično tkivo, v krvi.
Using Thyrogen to detect left over thyroid tissue following surgery was comparable with using the patients' own TSH after their replacement therapy was stopped. 
Uporaba zdravila Thyrogen za zaznavo preostalega ščitničnega tkiva po operaciji je bila primerljiva z uporabo bolnikom lastnega hormona TSH po prekinitvi nadomestnega zdravljenja.
Why has Thyrogen been approved? 
Zakaj je bilo zdravilo Thyrogen odobreno?
The presence of thyroid tissue can be checked by a blood test (showing that the thyroid protein thyroglobulin is being produced by any remaining thyroid tissue) or, if the patient has been given radioactive iodine, by a scan (showing that the remaining thyroid tissue is actively taking up the iodine). 
Prisotnost ščitničnega tkiva je mogoče preveriti s krvno preiskavo (ki pokaže, ali morebitno preostalo ščitnično tkivo proizvaja beljakovino ščitnice tiroglobulin) ali pa s slikanjem z radioaktivnim jodom, če ga je bolnik prejel (saj preostalo ščitnično tkivo aktivno privzame jod in tako postane vidno na sliki).
The larger published studies confirmed that Thyrogen had a similar effect to stopping replacement therapy in patients whose cancer had not spread to other parts of the body. 
V večjih objavljenih študijah so potrdili, da je imelo zdravilo Thyrogen pri bolnikih, pri katerih se rak ni razširil na druge dele telesa, podoben učinek kot prenehanje nadomestnega zdravljenja.
This study also compared Thyrogen with the patients' own TSH. 
V študiji so primerjali tudi zdravilo Thyrogen z bolnikom lastnim hormonom TSH.
Thyrogen is used in patients who have had thyroidectomy (thyroid surgery) because of cancer, to detect any thyroid tissue that might have been left over after the surgery. 
Zdravilo Thyrogen se uporablja pri bolnikih, pri katerih je bila zaradi raka izvedena tiroidektomija (operacija ščitnice), za odkrivanje ščitničnega tkiva, ki je morda ostalo po operaciji.
The company also presented the results of 13 studies from the published literature, including one key study that compared the effect of Thyrogen and the effect of stopping replacement therapy in 394 patients who were followed up for around two and a half years. 
Družba je predstavila tudi rezultate 13 študij iz objavljene literature, vključno z eno glavno študijo, v kateri so primerjali učinek zdravila Thyrogen in učinek prekinitve nadomestnega zdravljenja pri 394 bolnikih, ki so jih spremljali približno dve leti in pol. Z zdravilom Thyrogen sta bili opravljeni še dve objavljeni študiji, ki sta vključevali 1 190 bolnikov, pri katerih so uporabili nižje odmerke radioaktivnega joda.
Thyrogen was used in two studies to detect any remaining thyroid tissue in 381 patients who had had thyroidectomy (thyroid surgery). 
Zdravilo Thyrogen je bilo uporabljeno v dveh študijah za zaznavo morebitnega preostalega ščitničnega tkiva pri 381 bolnikih, pri katerih je bila izvedena tiroidektomija (operacija ščitnice).
Thyrogen can be used to eliminate remaining thyroid tissue when the patient is given higher doses of radioactive iodine. 
Zdravilo Thyrogen je mogoče uporabiti za odstranjevanje preostalega ščitničnega tkiva, kadar je bolnik prejel večje odmerke radioaktivnega joda.
However, patients who have had their thyroid gland removed receive medication (thyroid hormone replacement therapy) that stops their production of TSH. 
Bolniki, ki so jim odstranili žlezo ščitnico, prejemajo zdravila (nadomestno zdravljenje s hormonom tiroksinom), ki povzroči prenehanje nastajanja hormona TSH v telesu.
Thyrogen was used to eliminate any left-over thyroid tissue in a study involving 63 patients with thyroid cancer who were given higher doses of radioactive iodine. 
Zdravilo Thyrogen je bilo uporabljeno tudi za odstranjevanje morebitnega preostalega ščitničnega tkiva v študiji s 63 bolniki z rakom ščitnice, ki so prejeli večje odmerke radioaktivnega joda.
Another way to check for left-over tissue is to give the patient a dose of radioactive iodine that will show up in the thyroid tissue on a scan. 
Drugi način za preverjanje prisotnosti ostankov ščitničnega tkiva je dajanje radioaktivnega joda bolniku, ki se prikaže v tkivu ščitnice ob slikanju.
In these studies the ability of Thyrogen to stimulate left-over thyroid tissue was compared with the patients' own TSH. 
V teh dveh študijah so primerjali zmožnost zdravila Thyrogen za stimulacijo preostalega ščitničnega tkiva z bolnikom lastnim hormonom TSH.
How has Thyrogen been studied? 
Kako je bilo zdravilo Thyrogen raziskano?
How does Thyrogen work? 
Kako zdravilo Thyrogen deluje?
What is Thyrogen used for? 
Za kaj se zdravilo Thyrogen uporablja?
What is Thyrogen? 
Kaj je zdravilo Thyrogen?
How is Thyrogen used? 
Kako se zdravilo Thyrogen uporablja?
Please tell your doctor if: 
Povejte svojemu zdravniku, če:
Elderly (over 65 years of age) 
Starejši bolniki (starejši od 65 let)
This is so the doctor knows what you have taken. 
Tako bo zdravnik vedel, kaj ste vzeli.
The dose is the same as for adults. 
Odmerjanje je enako kot za odrasle.
Do not stop taking your tablets suddenly. 
Tablet ne prenehajte jemati nenadoma.
There is no known specific antidote. 
Znanega specifičnega antidota ni.
Tell your doctor immediately if you are pregnant or planning to become pregnant. 
Takoj povejte svojemu zdravniku, če ste noseči ali če načrtujete nosečnost.
Your doctor will decide whether you will be given this dose for one or two weeks. 
Zdravnik se bo odločil, ali boste ta odmerek prejemali en teden ali dva.
Adults There are two dosing regimes for adults: 
Odrasli Za odrasle obstajata dva režima odmerjanja:
Elderly (over 65 years of age) If you are elderly your doctor will decide the suitable dose for you. 
Starejši bolniki (starejši od 65 let) Če ste starejša oseba, bo zdravnik določil ustrezni odmerek za vas.
Monitoring and prevention 
Spremljanje in preventiva
Take the medicine pack with you. 
S seboj vzemite škatlo z zdravili.
The following side effects can be very serious. 
Naslednji neželeni učinki so lahko zelo resni.
If you forget to take a tablet, take it as soon as you remember and carry on as usual. 
Če pozabite vzeti tableto, jo vzemite takoj, ko se spomnite, in nadaljujte jemanje kot ponavadi.
In the newborn child 
Pri novorojencu
If this happens to you, do not drive or use any tools or machines. 
Če to opazite, ne vozite avtomobila niti ne upravljajte orodij ali strojev.
• Inability to speak or write or understand spoken or written language 
• nezmožnost govora, pisanja ali razumevanja izgovorjenih ali napisanih besed,
Do not take a double dose to make up for the one you have missed. 
Ne vzemite dvojnega odmerka, da nadomestite pozabljenega.
Use is therefore not recommended in these patients. 
Uporaba pri teh bolnikih torej ni priporočljiva.
It is important that your treatment is completed as advised by your doctor or your symptoms may get worse. 
Pomembno je, da zdravljenje končate tako, kot vam je naročil zdravnik, sicer se lahko simptomi poslabšajo.
Therefore, patients should be advised that their physical and/ or mental abilities needed for operating machinery or driving may be impaired and they are recommended not to do so until it has been established that their ability to perform such activities is not affected. 
Zato je treba bolnike obvestiti, da so lahko njihove fizične in/ali mentalne sposobnosti, ki so potrebne za upravljanje strojev ali vožnjo, zmanjšane, in jim priporočiti, da se tem dejavnostim izogibajo, dokler se ne ugotovi, da ni vpliva na njihovo zmožnost opravljanja teh dejavnosti.
However, due to interindividual variability, the effect may be clinically relevant in some individuals. 
Vendar je lahko zaradi velikih razlik med posamezniki ta učinek pri nekaterih posameznih klinično pomemben.
• Increased urine production during night time 
• zvečana tvorba urina ponoči,
The safety and efficacy of Exalief in children below 18 years has not yet been established. 
Varnost in učinkovitost zdravila Exalief pri otrocih starih do 18 let še nista bili dokazani.
These could be signs of an allergic reaction. 
To so lahko znaki alergijske reakcije.
• Increased or decreased appetite 
• zvečan ali zmanjšan apetit,
Dose when you start treatment 
Odmerek ob začetku zdravljenja
As per the CHMP Guideline on Risk Management Systems for medicinal products for human use, the updated RMP should be submitted at the same time as the next Periodic Safety Update Report (PSUR). 
V skladu s smernicamo CHMP o sistemih za obvladovanje tveganja za zdravila za uporabo v humani medicini mora biti posodobljen RMP predložen hkrati z naslednjim rednim posodobljenim poročilom o varnosti zdravila (PSUR).
• High or low blood pressure or a fall in blood pressure on standing up 
• visok ali nizek krvni tlak ali padec krvnega tlaka ob vstajanju,
DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 21.04.2009 
DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Datum pridobitve dovoljenja za promet: 21.04.2009
The mechanism of this risk is not known and the available data do not exclude the possibility of an increased risk for eslicarbazepine acetate. 
Mehanizem tveganja še ni znan, vendar razpoložljivi podatki ne izključujejo možnosti povečanega tveganja za eslikarbazepinacetat.
Pharmacotherapeutic group: Antiepileptics, Carboxamide derivatives, ATC code: N03AF04 
Farmakoterapevtska skupina: antiepileptiki, derivati karboksamida, oznaka ATC: N03AF04
Risk Management plan 
Načrt za obvladovanje tveganja (RMP)
• Difficulty in concentration 
• težave pri koncentraciji,
These could be signs of an allergic reaction 
To so lahko znaki alergijske reakcije;
In patients with CLCR <30 ml/min use is not recommended due to insufficient data. 
Pri bolnikih, pri katerih je CLCR < 30 ml/min, uporaba ni priporočena zaradi nezadostnih podatkov.
• Tell your doctor if you are taking hormonal/oral contraceptives. 
• Povejte zdravniku, če jemljete hormonske/peroralne kontraceptive.
Do not take Exalief if: 
Ne jemljite zdravila Exalief, če:
Apart from this, sodium levels should be determined during routine laboratory examination. 
Poleg tega je treba ravni natrija določiti tudi pri rutinskih laboratorijskih preiskavah.
When initiating or discontinuing treatment with Exalief or changing the dose, it may take 2 to 3 weeks to reach the new level of enzyme activity. 
Ob začetku ali prenehanju zdravljenja z zdravilom Exalief, ali pri spreminjanju njegovega odmerka, lahko doseganje nove ravni encimske aktivnosti traja 2 do 3 tedne.
Symptomatic and supportive treatment should be administered as appropriate. 
Po potrebi je treba uporabiti simptomatsko in podporno zdravljenje.
The presence of HLA-B*1502 allele in other ethnicities is negligible. 
Prisotnost alela HLA-B*1502 pri drugih narodnostih je zanemarljiva.
Minimum effective doses should be given, and monotherapy whenever possible should be preferred at least during the first three months of pregnancy. 
Kadar koli je mogoče, je treba uporabiti najmanjše učinkovite odmerke in samostojno zdravljenje, vsaj v prvih treh mesecih nosečnosti.
Based on individual response, the dose may be increased to 1200 mg once daily (see section 5.1). 
Glede na odziv posameznika se odmerek lahko zveča do 1.200 mg enkrat na dan (glejte poglavje 5.1).
Safety margins based on comparative exposure have thus not been established. 
Zato glede na primerjalno izpostavljenost meje varnosti niso bile ugotovljene.
• Feeling numb in any part of your body 
• občutek otrplosti v kateremkoli delu telesa,
• Ear pain or ringing in the ears 
• bolečine ali zvenenje v ušesih,
Your doctor may need to adjust the dose. 
Zdravnik vam bo morda prilagodil odmerek zdravila.
• you suffer from a heart disease such as heart failure or heart attack. 
• imate bolezen srca, kot sta srčno popuščanje ali srčna kap.
The usual maintenance dose is 800 mg once daily. 
Običajni vzdrževalni odmerek je 800 mg enkrat na dan.
Biotransformation 
Biološka transformacija
Valproate and levetiracetam 
Valproat in levetiracetam
• you suffer from a certain type of heart rhythm disorder (second or third degree atrioventricular (AV) block) 
• imate določeno vrsto okvare srčnega ritma (atrioventrikularni (AV) blok druge ali tretje stopnje)
SPECIAL WARNING THAT THE MEDICINAL PRODUCT MUST BE STORED OUT OF THE REACH AND SIGHT OF CHILDREN 
POSEBNO OPOZORILO O SHRANJEVANJU ZDRAVILA ZUNAJ DOSEGA IN POGLEDA
• Tell your doctor if you are taking tricyclic antidepressants e.g. amitriptyline. 
• Povejte zdravniku, če jemljete triciklične antidepresive, npr. amitriptilin.
If they happen to you stop taking Exalief and tell a doctor or go to a hospital immediately, as you may need urgent medical treatment: 
Če se pojavijo, nehajte jemati zdravilo Exalief in takoj povejte zdravniku ali pojdite v bolnišnico, saj morda potrebujete nujno zdravniško pomoč:
Your doctor will decide how long you should take Exalief for. 
Zdravnik se bo odločil, koliko časa morate jemati zdravilo Exalief.
Children Exalief is not to be given to children and adolescents. 
Otroci Zdravilo Exalief se ne sme dajati otrokom ali mladostnikom.
• Weight loss and general ill health (Cachexia) 
• izguba telesne mase in splošno slabo zdravje (kaheksija),