natgillin/translations-raw huggingface dataset:
• Try and space the doses evenly apart at times which are good for you - for example, first thing in the morning and then in the early evening. 
• Poskusite odmerke razporediti enakomerno tako, da vam bo najbolj ustrezalo - na primer zgodaj zjutraj, ko vstanete, in nato zgodaj zvečer.
DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 
DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Datum prve pridobitve dovoljenja za promet:
This improvement enables the body to fight infections that may have been present with no obvious symptoms. 
To izboljšanje omogoča telesu, da se brani pred okužbami, ki so bile prej prisotne brez očitnih simptomov.
Long-term animal carcinogenicity studies have not been performed. 
Dolgotrajnih študij kancerogenosti pri živalih niso izvajali.
You will probably find it most comfortable to: 
Najbrž vam bo najbolj ustrezalo, da:
It is believed that these symptoms are due to a recovery of the body's immune system. 
Menijo, da so ti simptomi posledica okrevanja imunskega sistema.
• The recommended dose is 90 mg twice a day for adults and adolescents (16 years and older). 
• Priporočeni odmerek je 90 mg dvakrat na dan, za odrasle in mladostnike (stare 16 let in več).
Your doctor should discuss this with you at that time. 
V tem primeru se bo zdravnik z vami o tem posebej pogovoril.
The severity of the pain and discomfort did not increase with treatment duration. 
Jakost bolečine in neugodja se ni povečevala s trajanjem zdravljenja.
Signs of previous infections 
Znaki predhodnih okužb
HIV attacks cells in your blood called CD4 or T-cells. 
Virus HIV napada celice v vaši krvi, ki se imenujejo CD4 ali T-celice.
A vial is suitable for single use only; unused portions must be discarded. 
Viala je primerna samo za enkratno uporabo; neporabljene dele moramo zavreči.
180 alcohol swabs. 
180 alkoholnih zložencev.
The marketing authorisation holder shall submit periodic safety update reports for this product in accordance with the requirements set out in the list of Union reference dates (EURD list) provided for under Article 107c(7) of Directive 2001/83/EC and published on the European medicines web-portal 
Imetnik dovoljenja za promet z zdravilom mora redno posodobljena poročila o varnosti zdravila za to zdravilo predložiti v skladu z zahtevami, določenimi v seznamu referenčnih datumov Unije (seznamu EURD), opredeljenem v členu 107c(7) Direktive 2001/83/ES in objavljenem na evropskem spletnem portalu o zdravilih.
Most adverse reactions were of mild or moderate intensity. 
Večina neželenih učinkov je bila blage ali zmerne intenzitete.
Includes discontinuations from loss to follow-up, treatment refusal, and other reasons. 
Vključuje prekinitve zaradi prekinitev spremljanja, zavrnitve zdravljenja in ostale vzroke.
Pinch as much of a skin fold as possible - without making yourself uncomfortable. 
Napravite tako veliko kožno gubo, kot je še mogoče, ne da bi vam bilo neprijetno.
Frequency categories are defined using the following convention: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); not known (cannot be estimated from the available data). 
Za razvrstitev pogostnosti je uporabljen naslednji dogovor: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1000 do < 1/100), redki (≥ 1/10.000 do < 1/1000), zelo redki (< 1/10.000), neznana (ni mogoče oceniti iz razpoložljivih podatkov).
995 patients comprised the intent-to-treat population. 
995 bolnikov so vključili v skupino, ki so jo nameravali zdraviti.
These signs do not definitely mean you are allergic to this medicine. 
Ti znaki še ne pomenijo zagotovo, da ste preobčutljivi na to zdravilo.
Wash hands thoroughly. 
Temeljito si umijte roke.
• The HIV virus in your blood may eventually become resistant to Fuzeon. 
• Virus HIV v vaši krvi lahko sčasoma postane odporen na zdravilo Fuzeon.
Fuzeon with food and drink 
Zdravilo Fuzeon skupaj s hrano in pijačo
Children ≥ 6 years and adolescents: The experience in children is limited (see section 5.2). 
Otroci ≥ 6 let in mladostniki: izkušnje pri otrocih so omejene (glejte poglavje 5.2).
Autoimmune disorders may occur many months after the start of treatment. 
Avtoimunske bolezni se lahko pojavijo več mesecev po začetku zdravljenja.
• Let the water flow slowly down the inside of the vial. 
• Voda naj znotraj viale počasi teče navzdol.
However, you still need to follow the instructions given in the package leaflets for the other medicines you are taking. 
Vendar pa se še vedno morate ravnati po navodilih za uporabo vaših drugih zdravil, ki jih jemljete.
The majority of patients had no change in the toxicity grade of any laboratory parameter during the study except for those listed in Table 4. 
Večina bolnikov med študijo ni imela spremembe v katerem koli laboratorijskem parametru za oceno toksičnosti, razen za tiste, ki so navedeni v preglednici 4.
● Once you have washed your hands, do not touch anything except the medicine and supplies. 
● Ko ste si umili roke, se ne dotikajte ničesar, razen zdravila in pripomočkov.
Step E: Disposing of used supplies 
Korak E: odlaganje uporabljenih potrebščin
Stop using Fuzeon and see a doctor straight away, if you notice any of the following serious side effects - you may need urgent medical treatment: 
Prenehajte jemati zdravilo Fuzeon in takoj poiščite zdravnika, če opazite katerega koli od sledečih resnih neželenih učinkov - morda boste potrebovali urgentno zdravniško pomoč:
This leaflet is available in all EU/EEA languages on the European Medicines Agency website. 
To navodilo za uporabo je na voljo v vseh uradnih jezikih EU/EGP na spletni strani Evropske agencije za zdravila.
Enfuvirtide should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. 
Enfuvirtid naj se med nosečnostjo uporablja samo, če možna korist upravičuje možno tveganje za plod.
Tip: Your doctor or nurse may suggest different injection techniques that will work best for you. 
Opomba: Vaš zdravnik ali medicinska sestra vam bosta morda predlagala drugačne metode injiciranja, ki vam bodo bolj ustrezale.
See further instructions on how to use Fuzeon at the end of this leaflet (see Section 7). 
Nadaljnji napotki, kako uporabljati zdravilo Fuzeon, so navedeni na koncu tega navodila za uporabo (glejte poglavje 7).
Discuss with your physician the precautions needed to avoid infecting other people. 
Pogovorite se z zdravnikom o potrebnih previdnostnih ukrepih, da se izognete prenosu okužbe na druge ljudi.
• Do not take a double dose to make up for a forgotten dose. 
• Nikoli ne vzemite dvojnega odmerka, da bi nadomestili pozabljeni odmerek.
It is bound predominantly to albumin and to a lower extent to α-1 acid glycoprotein. 
Veže se predvsem na albumine in v manjšem obsegu na α-1 kisle glikoproteine.
Although these syringes have this safety feature, it is still important that you dispose of used syringes properly. 
Čeprav imajo te brizge to varovalno lastnost, je pomembno, da uporabljene injekcijske brizge zavržete pravilno.
• Fuzeon is not a cure for HIV infection. 
• Fuzeon ni zdravilo za ozdravitev okužbe s HIV.
1Discontinuations or virological failures considered as failures. 
1Prekinitve ali virološki neuspehi, smatrani kot neuspeh.
• hold the syringe in your left hand and 
• držite injekcijsko brizgo v levi roki in
System organ class Frequency 
Organski sistem Pogostnost
Please be aware that the vial contains more liquid than you need (2 ml); you only have to pull out 1.1 ml to prepare your injection properly. 
Prosimo upoštevajte, da viala vsebuje več tekočine, kot je potrebujete (2 ml); za pravilno pripravo vaše injekcije je morate odvzeti le 1,1 ml.
Any inflammatory symptoms should be evaluated and treatment instituted when necessary. 
Kakršne koli vnetne simptome je treba obravnavati in uvesti zdravljenje, kadar je potrebno.
● Wash your hands well. 
● Temeljito si umijte roke.
While effective viral suppression with antiretroviral therapy has been proven to substantially reduce the risk of sexual transmission, a residual risk cannot be excluded. 
Čeprav se je izkazalo, da učinkovita virusna supresija s protiretrovirusno terapijo bistveno zmanjša tveganje spolnega prenosa, preostalega tveganja ni mogoče izključiti.
They may also be worse when the injection is given deeper than intended (for example, into a muscle). 
kadar je injekcija dana globlje, kot je namenjeno (na primer v mišico).
Few patients included in the phase III trials were co-infected with hepatitis B/C. 
Nekaj bolnikov, vključenih v preskušanja faze III, je bilo okuženih tudi s hepatitisom B/C.
You can use Fuzeon with or without food. 
Zdravilo Fuzeon lahko uporabite ob obroku ali brez njega.
Chemical and physical in-use stability has been demonstrated for 48 hours at 5°C when protected from light. 
Podatki pri uporabi kažejo kemijsko in fizikalno stabilnost 48 ur pri 5 °C, če je zdravilo zaščiteno pred svetlobo.
The clinical relevance of these findings is unknown. 
Pomen teh dognanj za klinično uporabo ni znan.
The virus needs to make contact with, and get inside these cells in order for the virus to multiply. 
Virus mora imeti stik s celico in vanjo vstopiti, zato da se lahko v njej razmnožuje.
• Be careful not to forcefully shoot water into the powder, since this can cause foaming. 
• Bodite previdni, da vode prehitro s silo ne iztisnete v prašek, ker to lahko povzroči penjenje.
Animal studies do not indicate harmful effects with respect to foetal development. 
Študije na živalih ne kažejo na škodljive vplive na razvoj plodu.
In deciding on a new regimen for patients who have failed an antiretroviral regimen, careful consideration should be given to the treatment history of the individual patient and the patterns of mutations associated with different medicinal products. 
Pri odločanju o novem režimu zdravljenja za bolnike, pri katerih je bil protiretrovirusni režim zdravljenja neuspešen, moramo skrbno preučiti anamnezo zdravljenja posameznega bolnika in vzorce mutacij, povezane z različnimi zdravili.
You should not use Fuzeon unless specifically told to by your doctor. 
Zdravila Fuzeon ne smete uporabiti, razen če vam je vaš zdravnik to izrecno naročil.
There is no evidence that enfuvirtide may alter the patient's ability to drive and use machines, however, the adverse event profile of enfuvirtide should be taken into account (see section 4.8). 
Ni dokazov, da bi enfuvirtid lahko spremenil bolnikovo sposobnost vožnje in upravljanja strojev, vendar pa je treba upoštevati profil neželenih dogodkov enfuvirtida (glejte poglavje 4.8).
Excipient with known effect: sodium. 
Pomožne snovi z znanim učinkom: natrij.
Please also refer to the respective summary of product characteristics of the other antiretroviral medicinal products used in the combination. 
Prosimo, glejte tudi povzetke glavnih značilnosti zdravila za druga protiretrovirusna zdravila, ki se uporabljajo v kombinaciji.
Where to Inject 
Kam injicirati
Antiretroviral drug resistance: Incomplete viral suppression may lead to the development of drug resistance to one or more components of the regimen. 
Odpornost proti protiretrovirusnim zdravilom: nepopolna virusna supresija lahko vodi v razvoj odpornosti proti zdravilom za eno ali več sestavin režima zdravljenja.
● Never use a syringe with a bent or damaged needle. 
● Nikoli ne uporabljajte injekcijske brizge z zvito ali poškodovano iglo.
• feeling anxious or irritated 
• občutek tesnobe ali razdraženosti,
You may like to ask someone to come with you to an injection training session with your doctor or nurse. 
Lahko tudi prosite nekoga, da gre z vami na usposabljanje za injiciranje pri vašem zdravniku ali medicinski sestri.
In case of concomitant antiviral therapy for hepatitis B or C, please refer also to the relevant product information for these medicinal products. 
V primeru sočasnega protivirusnega zdravljenja za hepatitis B ali C, prosimo, glejte tudi ustrezna navodila za ta zdravila.
● Never inject your medicine with other injectable medicines. 
● Svojega zdravila nikoli ne injicirajte z drugimi zdravili za injiciranje.
Animal studies have shown that enfuvirtide may impair some immune functions (see section 5.3). 
Študije na živalih so pokazale, da lahko enfuvirtid oslabi nekatere funkcije imunskega sistema (glejte poglavje 5.3).
This includes medicines obtained without a prescription and herbal medicines. 
To vključuje tudi zdravila brez recepta in zdravila rastlinskega izvora.
Combination studies of enfuvirtide with representative members of the various antiretroviral classes exhibited additive to synergistic antiviral activities and an absence of antagonism. 
Študije kombinacij enfuvirtida z reprezentativnimi predstavniki različnih protivirusnih razredov so pokazale dodatne sinergistične protivirusne aktivnosti in odsotnost antagonizma.
Powder 4 years 
Prašek 4 leta
This pack provides you with everything you need to prepare and take your Fuzeon for 30 days of injections. 
V tem zavitku je vse, kar potrebujete za pripravo in jemanje vašega zdravila Fuzeon za 30 dni injiciranja.
** M-H test: Discontinuations or virological failure considered as failures. 
** M-H test: prekinitve zdravljenja ali virološki neuspehi smatrani kot neuspehi.
Patients with liver disease 
Bolniki z jetrno boleznijo
Push the needle into the skin at a 45-degree angle. 
Potisnite injekcijsko iglo v kožo pod kotom 45 stopinj.
% of Event comprising Grade 4 reactions 
% dogodkov, ki predstavljajo reakcije 4.
Less than 13% of the dose was removed during haemodialysis. 
Med hemodializo se je odstranilo manj kot 13 % odmerka.
The geometric mean changes ranged from 15.2 fold for V38M to 41.6 fold for V38A. 
Geometrična sredina sprememb je bila v razponu od 15,2-krat za V38M do 41,6-krat za V38A.
gGrade 3= > 3 cm but ≤ 5 cm; Grade 4= > 5 cm. 
gStopnja 3 = > 3 cm, toda ≤ 5 cm; stopnja 4 = > 5 cm.
If not, store in a refrigerator and use within 24 hours. 
Če ga ne, ga shranite v hladilnik in uporabite v 24 urah.
% of Event comprising Grade 3 reactions 
% dogodkov, ki predstavljajo reakcije 3.
Other medicines and Fuzeon 
Druga zdravila in zdravilo Fuzeon
Injection site reactions (ISRs) were the most frequently reported adverse reaction and occurred in 98% of the patients (Table 3). 
Reakcije na mestu injiciranja so bile najpogostejši neželeni učinek, o katerem so poročali in so se pojavile pri 98 % bolnikov (preglednica 3).
Step A: Getting Started 
Korak A: začetna priprava
If there is evidence of particulate matter, the vial must not be used and should be discarded or returned to the pharmacy. 
Če so vidni delci, viale ne sme uporabiti in jo mora zavreči ali vrniti v lekarno.
• shaking (tremor) 
• tresenje (tremor),
• Do not inject into areas that could become irritated by your belt or the waistline of your clothes. 
• Ne injicirajte v mesta, ki jih lahko draži vaš pas ali rob vaših oblačil.
He did not experience an adverse reaction as a result. 
Posledično ni občutil nobenih neželenih učinkov.
How much to use 
Koliko zdravila uporabiti
Precautions to prevent transmission should be taken in accordance with national guidelines. 
V skladu z nacionalnimi smernicami je treba sprejeti previdnostne ukrepe za preprečevanje prenosa.
fGrade 3= refractory to topical treatment or requiring oral or parenteral treatment; Grade 4= not defined. 
fStopnja 3 = refraktarno za lokalno zdravljenje, ali ki zahteva peroralno ali parenteralno zdravljenje; stopnja 4 = ni definirano.
This may feel like lumps under the skin. 
To lahko občutite kot podkožne grudice.
As with other antiretrovirals, enfuvirtide should optimally be combined with other antiretrovirals to which the patient's virus is sensitive (see section 5.1). 
Kot velja za druga protiretrovirusna zdravila, enfuvirtid optimalno kombiniramo z drugimi protiretrovirusnimi zdravili, za katere je bolnikov virus občutljiv (glejte poglavje 5.1).
CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE 
B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE
This metabolite is detected in human plasma following administration of enfuvirtide, with an AUC ranging from 2.4 to 15% of the enfuvirtide AUC. 
Presnovek zaznamo v človeški plazmi po dajanju enfuvirtida, z AUC v obsegu od 2,4 do 15 % AUC enfuvirtida.
If you forget to use Fuzeon 
Če ste pozabili uporabiti zdravilo Fuzeon
● Never use or share used needles. 
● Nikoli ne uporabite ali delite že uporabljenih igel.
No case of overdose has been reported. 
Ni poročil o primerih prevelikega odmerjanja.
The resistance to influenza and streptococcal infection in rats was only weakly compromised. 
Odpornost proti gripi in okužbi s streptokoki je bila pri podganah le malo zmanjšana.
If you notice any symptoms of infection or other symptoms such as muscle weakness, weakness beginning in the hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity, please inform your doctor immediately to seek necessary treatment. 
Če opazite kakršne koli simptome okužbe ali druge simptome, na primer mišično oslabelost, oslabelost, ki se najprej pojavi v dlaneh in stopalih in nato širi proti trupu, palpitacije, tremor ali hiperaktivnost zaradi potrebnega zdravljenja, nemudoma obvestite zdravnika.
This side effect is rare (affects less than 1 in 1,000 people). 
Ta neželeni učinek je redek (pojavi se pri manj kot 1 od 1.000 bolnikov).
• If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. 
Nosečnost in dojenje • Če ste noseči, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom, preden vzamete to zdravilo.
In an Early Access Program study, one patient was administered 180 mg of Fuzeon as a single dose on one occasion. 
V študijah programa predhodne dostopnosti (Early Access Program study) je en bolnik enkrat prejel 180 mg zdravila Fuzeon v enkratnem odmerku.
Any unused medicinal product should be disposed of in accordance with local requirements. 
Neuporabljeno zdravilo zavrzite v skladu z lokalnimi predpisi.
1 copies/ml 
kopij/ml
MARKETING AUTHORISATION NUMBER(S) EU/1/03/252/001 
ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/03/252/001
This is attached to the needle and covers it after use to lower the risk of the needle accidently pricking another person. 
Pripomoček je pritrjen na iglo in jo po uporabi pokrije ter s tem zmanjša tveganje, da bi se kdo drug po nesreči zbodel.
There you will find instructions on how to prepare Fuzeon and how to give yourself an injection. 
Tam boste našli navodila, kako pripraviti zdravilo Fuzeon in kako si dati injekcijo.
Discontinued due to other reasons†φ§ 
4 % ni na voljo prekinitev zaradi drugih vzrokov †φ§
• you have chronic hepatitis B or C or another liver disease - you are more likely to get serious liver problems while using this medicine 
• imate kronični hepatitis B ali C ali drugo jetrno bolezen - obstaja večja verjetnost, da se ob jemanju tega zdravila pojavijo resne težave z jetri.
If it is not used straight away it must be stored in a refrigerator (2°C - 8°C) and used within 24 hours. 
Če je ne uporabite takoj, jo shranite v hladilniku (2 °C - 8 °C) in uporabite v 24 urah.
After pulling out the needle 
Ko ste izvlekli iglo
No studies on the effects on the ability to drive and use machines have been performed. 
Študije o vplivu na sposobnost vožnje in upravljanja strojev niso bile izvedene.
If you are preparing both of your daily doses at one time, make sure to use new syringes, Water for Injections, and Fuzeon for each dose. 
Če sočasno pripravljate oba dnevna odmerka, poskrbite, da za vsak odmerek uporabite novo injekcijsko brizgo, novo vodo za injekcije in novo zdravilo Fuzeon.
This injects the air. 
Tako iztisnete zrak.
These substitutions were correlated with varying levels of reduced enfuvirtide susceptibility in HIV sitedirected mutants. 
Te substitucije so bile korelirane z različnimi stopnjami zmanjšane dovzetnosti za enfuvirtid v lokacijsko usmerjenih mutantah HIV.
• Do not breast-feed if you have HIV because HIV may be passed on to the baby. 
• Če ste okuženi z virusom HIV, ne smete dojiti, saj se lahko virus HIV prenese na otroka.
Gender and Weight: Analysis of plasma concentration data from patients in clinical trials indicated that the clearance of enfuvirtide is 20% lower in females than males irrespective of weight and is increased with increased body weight irrespective of gender (20% higher in a 100 kg and 20% lower in a 40 kg body weight patient relative to a 70 kg reference patient). 
Spol in telesna masa: analiza podatkov o plazemskih koncentracijah pri bolnikih v kliničnih preskušanjih je pokazala, da je očistek enfuvirtida ne glede na telesno maso 20 % nižji pri ženskah v primerjavi z moškimi in poraste s povečanjem telesne mase ne glede na spol (20 % višji pri bolniku s telesno maso 100 kg in 20 % nižji pri bolniku s telesno maso 40 kg v primerjavi z referenčnim bolnikom s telesno maso 70 kg).
Risk factors that may predict the occurrence or severity of hypersensitivity to enfuvirtide have not been identified. 
Dejavniki tveganja, na osnovi katerih bi lahko predvideli pojav ali resnost preobčutljivosti za enfuvirtid, niso bili določeni.
 Risk factors for developing this disease include: how long you have been taking anti-HIV medicines, whether you take corticosteroids, how much alcohol you drink, how well your immune system works and being overweight. 
• Dejavniki tveganja za pojav te bolezni vključujejo: čas jemanja zdravil proti virusu HIV, jemanje kortikosteroidov, količino zaužitega alkohola, kako dobro deluje vaš imunski sistem in če imate preveliko telesno maso.
The addition of Fuzeon to background antiretroviral therapy generally did not increase the frequency or severity of most adverse reactions. 
Dodatek zdravila Fuzeon temeljnemu protiretrovirusnemu zdravljenju v splošnem ni povečal pogostnosti ali resnosti večine neželenih učinkov.
● Never mix your medicine with tap water. 
● Svojega zdravila nikoli ne mešajte z vodo iz pipe.
After reconstitution: Store in a refrigerator (2°C - 8°C). 
Po rekonstituciji shranjujte v hladilniku (2-8 °C).
You can still pass on HIV when taking this medicine, although the risk is lowered by effective antiretroviral therapy. 
Med jemanjem tega zdravila okužbo z virusom HIV še vedno lahko prenesete na drugo osebo, čeprav je tveganje zmanjšano z učinkovitim protiretrovirusnim zdravljenjem.
Elderly: There is no experience in patients > 65 years old. 
Starejši: pri bolnikih, starejših od 65 let, ni izkušenj.
Slowly pull back the plunger until the water reaches the 1.1 ml mark. 
Počasi izvlecite bat, dokler voda ne doseže oznake 1,1 ml.
The relationship of these substitutions to in vivo effectiveness of enfuvirtide has not been established. 
Razmerje teh substitucij do in vivo učinkovitosti enfuvirtida ni bilo ugotovljeno.
Bone disease (osteonecrosis) 
Bolezni kosti (osteonekroza)
Fuzeon should be prescribed by physicians who are experienced in the treatment of HIV infection. 
Zdravilo Fuzeon naj predpisujejo zdravniki z izkušnjami pri zdravljenju okužbe s HIV.
When to have someone to help you 
Če potrebujete pomoč,
In these the addition of Fuzeon did not increase the incidence of hepatic events. 
Pri njih dodatek zdravila Fuzeon ni povečal pojavnosti jetrnih dogodkov.
Conversely, mutations in aa 36-45 of gp41 which give resistance to enfuvirtide would not be expected to give cross resistance to other classes of antiretrovirals. 
Nasprotno se za mutacije v AK 36-45 glikoproteina 41, ki dajejo odpornost proti enfuvirtidu, ne bi pričakovalo, da bi dale navzkrižno odpornost proti drugim razredom protiretrovirusnih učinkovin.
If this happens, your blood levels of virus may begin to rise. 
Če se bo to zgodilo, bodo koncentracije virusa v krvi ponovno pričele rasti.
Patients should be advised to seek medical advice if they experience joint aches and pain, joint stiffness or difficulty in movement. 
Bolnikom je treba svetovati, naj poiščejo zdravniško pomoč, če se jim pojavijo bolečine v sklepih, togost sklepov ali težave z gibljivostjo.
In vitro human microsomal studies and in in vivo studies indicate that enfuvirtide is not an inhibitor of CYP450 enzymes. 
In vitro mikrosomalne študije pri ljudeh ter in vivo študije kažejo, da enfuvirtid ni zaviralec encimov CYP450.