natgillin/translations-raw huggingface dataset:
Choice of other medicinal products and dose selection should be considered accordingly, as adverse reactions may continue and efficacy may, at least partly, persist until albiglutide levels decline. 
To je treba ustrezno upoštevati pri izbiri drugih zdravil in njihovega odmerka, ker se neželeni učinki lahko nadaljujejo, učinek pa lahko vsaj deloma traja, dokler se koncentracija albiglutida ne zniža.
Adverse reactions from phase III studies during the entire treatment periods and postmarketing reports 
Neželeni učinki v študijah III. faze med celotnim obdobjem zdravljenja in poročilih iz obdobja po prihodu zdravila na trg.
These data exclude the use of antidiabetic therapies permitted after the efficacy assessment if glycaemic thresholds were exceeded. 
Ti podatki ne vključujejo uporabe antidiabetičnih zdravil, dovoljenih po oceni učinkovitosti, če so bili preseženi pragi glikemije.
Patients treated with albiglutide should be advised of the potential risk of dehydration, and take precautions to avoid fluid depletion. 
Bolnike, ki se zdravijo z albiglutidom, je treba poučiti o možnem tveganju dehidracije in jim svetovati ukrepe v izogib izgube tekočin.
Don't use Eperzan: 
Ne uporabljajte zdravila Eperzan:
A few drops of liquid may come out of the needle. 
Iz igle lahko priteče nekaj kapljic tekočine.
The needle must be attached to allow air to escape while turning the cartridge from [2] to [3] in the number window. 
Iglo je treba namestiti, da gre lahko iz nje zrak, medtem ko sučete vložek z [2] na [3] v številčnem okencu.
The dose may be increased to 50 mg once weekly based on individual glycaemic response. 
Odmerek je mogoče zvišati na 50 mg enkrat na teden glede na posameznikov glikemični odziv.
Speak to your doctor about how to recognise the symptoms of ketoacidosis and seek urgent medical treatment if they occur. 
Z zdravnikom se posvetujte o tem, kako prepoznati simptome ketoacidoze; če se vam takšni simptomi pojavijo, poiščite nujno zdravniško pomoč.
Your doctor may increase your dose to 50 mg once weekly if your blood sugar is not controlled by the 30 mg dose. 
Zdravnik vam lahko odmerek zviša na 50 mg enkrat na teden, če vaš krvni sladkor z odmerkom 30 mg ni urejen.
If you miss a dose, inject the next dose as soon as possible within 3 days after the missed dose. 
Če izpustite odmerek, si naslednji odmerek injicirajte čim prej v 3 dneh po izpuščenem odmerku.
Japanese patients showed approximately 30 to 40% higher exposures than Caucasians, likely attributable to lower body weight. 
Pri japonskih bolnikih je bila izpostavljenost približno 30 do 40 % večja kot pri belcih, verjetno zaradi manjše telesne mase.
In addition, albiglutide did not significantly alter the pharmacodynamic effects of warfarin as measured by the international normalized ratio. 
Poleg tega albiglutid ni pomembno spremenil farmakodinamičnih učinkov varfarina, merjeno z internacionalnim normaliziranim razmerjem.
When Eperzan is added to existing metformin therapy, the current metformin dose can be continued unchanged. 
Če je zdravilo Eperzan dodano obstoječemu zdravljenju z metforminom, se lahko metformin še naprej uporablja v nespremenjenem odmerku.
Step 8 Deliver injection 8a Insert needle straight into the injection site. 
8. korak Injicirajte 8a Zabodite iglo naravnost v mesto za injiciranje.
Based on the results of population pharmacokinetic analyses, there is no clinically relevant effect of gender on clearance. 
Na podlagi rezultatov populacijskih farmakokinetičnih analiz spol nima klinično pomembnega vpliva na očistek.
It is unknown whether the reduced offspring body weight was caused by a direct albiglutide effect on the offspring or secondary to effects on the dam. 
Ni znano, ali je bil vzrok zmanjšane telesne mase mladičev neposreden učinek albiglutida na mladiče ali sekundaren zaradi učinkov na samice-matere.
Injection Button* 
Gumb za injiciranje*
Check Medicine 
Preverite zdravilo
Pharmacotherapeutic group: Drugs used in diabetes. 
Farmakoterapevtska skupina: Zdravila za zdravljenje diabetesa.
At the end of this period the pen should be used or discarded. 
Po koncu tega obdobja je treba peresnik uporabiti ali zavreči.
DO NOT use pen if there are still particles in the liquid. 
NE UPORABITE peresnika, če so v tekočini še vedno delci.
Eperzan should be discontinued at least 1 month before a planned pregnancy due to the long washout period for albiglutide. 
Zdravilo Eperzan je treba prenehati uporabljati vsaj 1 mesec pred načrtovano zanositvijo, ker je obdobje izpiranja albiglutida dolgo.
It may affect up to 1 in 100 people. 
Pojavi se lahko pri do 1 od 100 oseb.
Never mix insulin and Eperzan together. 
Insulina in zdravila Eperzan nikdar ne zmešajte.
Other Supplies Needed 
Druge potrebščine
If pancreatitis is suspected, Eperzan should be discontinued; if pancreatitis is confirmed, Eperzan should not be restarted. 
V primeru suma na pankreatitis je treba uporabo zdravila Eperzan prekiniti; če je pankreatitis potrjen, se zdravila Eperzan ne sme več uvesti.
If it has been more than 8 hours since the medicine was mixed in Step 2, throw away the pen and use another pen. 
Če je od mešanja zdravila v 2. koraku minilo že več kot 8 ur, peresnik zavrzite in uporabite drugega.
Eperzan should be administered once a week on the same day each week. 
Zdravilo Eperzan je treba uporabljati enkrat na teden, vsak teden na isti dan.
The most serious adverse reaction in clinical trials was acute pancreatitis (see section 4.4). 
Najresnejši neželeni učinek v kliničnih preskušanjih je bil akutni pankreatitis (glejte poglavje 4.4).
IMPORTANT: Make sure you have waited 30 minutes before continuing onto step 4. 
POMEMBNO: Prepričajte se, da ste počakali 30 minut, preden nadaljujete s 4. korakom.
Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. 
Preobčutljivost na zdravilno učinkovino ali katero koli pomožno snov, navedeno v poglavju 6.1
Diarrhoea (13% versus 9%), nausea (12% versus 11%), vomiting (5% versus 4%), and constipation (5% versus 4%) were the most frequently reported, and the majority of events occurred within the first 6 months. 
Najpogosteje zabeleženi so bili driska (13 % v primerjavi z 9 %), navzea (12 % v primerjavi z 11 %), bruhanje (5 % v primerjavi s 4 %) in zaprtost (5 % v primerjavi s 4 %); večina učinkov se je pojavila v prvih 6 mesecih.
If the pen is jammed or leaking, throw it away and use another pen. 
Če se peresnik zatakne ali pušča, ga zavrzite in uporabite drugega.
Therapeutic proteins such as albiglutide are catabolised by widely distributed proteolytic enzymes, which are not restricted to hepatic tissue; therefore, changes in hepatic function are unlikely to have any effect on the elimination of Eperzan (see section 4.2). 
Terapevtske beljakovine, kakršna je albiglutid, se katabolizirajo s široko razprostranjenimi proteolitičnimi encimi, ki niso omejeni na jetrno tkivo, zato ni verjetno, da bi spremembe delovanja jeter vplivale na odstranjevanje zdravila Eperzan (glejte poglavje 4.2).
Wait 30 Minutes 
Počakajte 30 minut
8c After hearing the “click,” continue holding down the injection button and slowly count to 5 to deliver the full dose of medicine (Figure T). 
8c Potem ko zaslišite "klik", še naprej držite gumb za injiciranje pritisnjen dol ter počasi preštejte do 5, da boste injicirali celotni odmerek zdravila (Slika T).
What if I do not attach the needle at Step 5? 
Kaj, če igle ne namestim v 5. koraku?
A decrease in halflife of simvastatin and simvastatin acid from ~7 hours to 3.5 hours was observed. 
Razpolovni čas simvastatina in simvastatinske kisline se je skrajšal s ~7 ur na 3,5 ure.
DO NOT rest the back of the device (where the injection button is exposed) on a flat surface while removing needle caps. 
NE POLAGAJTE zadnjega dela peresnika (na katerem je izpostavljen gumb za injiciranje) na ravno površino, medtem ko snemate pokrovčka igle.
For full instructions on the reconstitution and administration of Eperzan see section 6.6 and the instructions for use included in the package leaflet. 
Za celotna navodila za pripravo in dajanje zdravila Eperzan glejte poglavje 6.6 in navodila, ki jih vsebuje navodilo za uporabo.
These findings are consistent with lactational ileus syndrome which has been previously reported in mice. 
Ti izsledki se skladajo s sindromom laktacijskega ileusa, ki je bil že opisan pri miših.
If it is more than 3 days since you missed your dose, wait until your usually scheduled day for your next injection. 
Če so od tedaj, ko ste izpustili odmerek, minili že več kot 3 dnevi, počakajte na svoj običajni, predvideni dan za naslednjo injekcijo.
1c Check that the pen has a [1] in the number window (Figure F). 
1c Preverite, da ima peresnik v številčnem okencu [1] (Slika F).
If the needle is attached before Step 5, some of the medicine may be lost during mixing. 
Če iglo namestite prej kot v 5. koraku, lahko med mešanjem izgubite nekaj zdravila.
Generally, injection site reactions were mild in intensity and did not require treatment. 
Na splošno so bile reakcije na mestu injiciranja blage in jih ni bilo treba zdraviti.
• A clean empty cup (Figure C). 
• Prazno, čisto posodico (Slika C)
IMPORTANT: Make sure you have waited 15 minutes before continuing onto step 4. 
POMEMBNO: Prepričajte se, da ste počakali 15 minut, preden nadaljujete s 4. korakom.
Throw out the pen in a container for pen disposal right away after injecting, as shown in Step 9. 
Peresnik takoj po injiciranju zavrzite v vsebnik za odlaganje, kot je prikazano v 9. koraku.
Eperzan has not been studied in patients with severe gastrointestinal disease, including severe gastroparesis, and therefore it is not recommended in these patients. 
Zdravilo Eperzan ni raziskano pri bolnikih s hudo boleznijo prebavil, vključno s hudo gastroparezo, zato pri takšnih bolnikih ni priporočljivo.
The use of Eperzan does not require specific blood glucose self-monitoring. 
Uporaba zdravila Eperzan ne zahteva specifičnega samomerjenja glukoze v krvi.
Albiglutide is a recombinant fusion protein consisting of two copies of a 30-amino acid sequence of modified human glucagon-like peptide 1 genetically fused in series to human albumin. 
Albiglutid je rekombinantna fuzijska beljakovina, sestavljena iz dveh kopij zaporedja 30 aminokislin modificiranega humanega glukagonu podobnega peptida 1, v zaporedjih genetsko vezanega na humani albumin.
The percentage of patients who developed antibodies to albiglutide on treatment was 4% (137/3,267). 
Med zdravljenjem so se protitelesa proti albiglutidu pojavila pri 4 % (137/3.267) bolnikov.
In both the Eperzan and all comparator groups, patients with events were generally male, older, or had renal impairment. 
Tako v skupini z zdravilom Eperzan kot v skupinah z vsemi primerjalnimi zdravili so bili bolniki z dogodki na splošno moški, starejši in z okvaro ledvic.
Caution should be exercised in patients receiving medicinal products with a narrow therapeutic index or medicinal products that require careful clinical monitoring. 
zdravljenih z zdravili, ki imajo ozek terapevtski indeks ali zahtevajo skrbno klinično spremljanje.
In addition, a clinical pharmacology study showed a similar increased exposure for patients with moderate or severe renal impairment or those on haemodialysis relative to patients without renal impairment. 
Poleg tega je klinična farmakološka študija pokazala podobno povečanje izpostavljenosti pri bolnikih z zmerno ali hudo okvaro ledvic ali tistih na hemodializi glede na bolnike brez okvare ledvic.
This is to make sure the medicine has dissolved. 
Tako boste zagotovili, da se je zdravilo raztopilo.
Eperzan helps your body to increase the production of insulin when your blood sugar is high. 
Zdravilo Eperzan telesu pomaga povečati nastajanje insulina, kadar imate visok krvni sladkor.
What Eperzan is and what it is used for 
Kaj je zdravilo Eperzan in za kaj ga uporabljamo
Push Down Slowly 
Počasi potiskajte dol
The pen has the medicine powder in one compartment and the water in another compartment. 
Peresnik vsebuje v enem razdelku prašek z zdravilom in v drugem razdelku vodo.
• After the powder and liquid are mixed within the pen, the pen should be used within 8 hours. 
• Po tem, ko prašek in tekočino v peresniku premešate, morate peresnik uporabiti v 8 urah.
Eperzan is not recommended if you have these 
Zdravilo Eperzan ni priporočljivo, če imate te bolezni.
Thereafter, patients can resume dosing on their usual day of administration. 
Potem lahko bolnik nadaljuje uporabo na svoj običajni dan dajanja zdravila.
Inspect the pen for ‘1' in the number window and expiration date. 
Preglejte peresnik za številko "1" v številčnem okencu in datum uporabe.
Albiglutide is produced in Saccharomyces cerevisiae cells by recombinant DNA technology. 
Albiglutid je pridobljen v celicah Saccharomyces cerevisiae s tehnologijo rekombinantne DNA.
If you are pregnant or breast-feeding, if you think you may be pregnant, or are planning to have a baby, ask your doctor, nurse or pharmacist for advice before using this medicine. 
Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom, medicinsko sestro ali farmacevtom, preden uporabite to zdravilo.
Active-controlled study versus sitagliptin in patients with type 2 diabetes and different degrees of renal impairment 
Z aktivno učinkovino kontrolirana študija v primerjavi s sitagliptinom pri bolnikih s sladkorno boleznijo tipa 2 in različnimi stopnjami okvare ledvic
Among patients randomised to other comparators, the incidence of symptomatic hypoglycaemia was 7% to 33% when used with a sulphonylurea or insulin and 2% to 4% in combinations without these medicinal products. 
Med bolniki, randomiziranimi na druga primerjalna zdravila, je bila incidenca simptomatskih hipoglikemij od 7 do 33 % med uporabo s sulfonilsečnino ali insulinom in od 2 do 4 % v kombinaciji brez teh zdravil.
Other medicines and Eperzan 
Druga zdravila in zdravilo Eperzan
Severe allergic reactions 
Resne alergijske reakcije
Complete dissolution for the 30 mg pen usually occurs within 2 minutes but may take up to 5 minutes, as confirmed by visual inspection for a clear solution free of particles. 
Popolna raztopitev je s 30-mg peresnikom po navadi dosežena v 2 minutah, a lahko traja do 5 minut; raztopitev potrdite s pregledom raztopine, ki mora biti bistra in brez delcev.
Once weekly 
Enkrat na teden
Given that albiglutide is an albumin-based protein therapeutic agent, it is likely to be present in human milk. 
Glede na to, da je albiglutid beljakovinsko zdravilo na podlagi albumina, je verjetno prisoten v materinem mleku pri človeku.
7c Place both needle caps into a container for pen disposal. 
7c Oba pokrovčka igle zavrzite v vsebnik za odlaganje peresnika.
1b Check dosage and expiration date on pen (Figure E). 
1b Na peresniku preverite odmerek in datum izteka roka uporabnosti peresnika (Slika E).
However, in healthy volunteers following 50 mg the steady state concentration was 7.39 µg/ml at day 36, thus higher than population PK analyses from phase III patient studies predicted. 
Toda pri zdravih prostovoljcih je bila koncentracija v stanju dinamičnega ravnovesja po odmerku 50 mg 36. dan 7,39 µg/ml in torej višja kot napovedana v populacijskih farmakokinetičnih analizah v študijah III. faze pri bolnikih.
Frequency categories below reflect combined data for the 2 doses of Eperzan, 30 mg or 50 mg weekly subcutaneously. 
Spodaj navedene kategorije pogostnosti odražajo združene podatke za 2 odmerka zdravila Eperzan, 30 mg ali 50 mg na teden subkutano.
Figure 1: Kaplan-Meier curve showing durability of glycaemic control (measured by time to rescue) for Eperzan, relative to two active controls (sitagliptin and glimepiride) and placebo 
Slika 1: Kaplan-Meierjeva krivulja, ki prikazuje trajnost urejenosti glikemije (merjeno s časom do rešilnega ukrepanja) za zdravilo Eperzan glede na dve aktivni primerjalni učinkovini (sitagliptin in glimepirid) in placebo
The majority of the observed reduction in fasting plasma glucose occurs after a single dose, consistent with the pharmacokinetic profile of albiglutide. 
Večina opaženega znižanja glukoze v plazmi na tešče se pojavi po posameznem odmerku; to se sklada s farmakokinetičnimi značilnostmi albiglutida.
Clean Empty Cup Clock/Timer 
Prazna, čista posodica Ura/štoparica
Eperzan must not be injected into a vein (intravenously) or into a muscle (intramuscularly). 
Zdravila Eperzan ne smete injicirati v veno (intravensko) ali v mišico (intramuskularno).
Eperzan has no or negligible influence on your ability to drive or use machines. 
Zdravilo Eperzan nima ali ima zanemarljiv vpliv na vašo sposobnost vožnje in upravljanja s stroji.
In a population pharmacokinetic analysis including a phase III trial in patients with mild, moderate and severe renal impairment, exposures were increased by approximately 30 to 40% in severe renal impairment compared to those observed in type 2 diabetic patients with normal renal function. 
V populacijski farmakokinetični analizi vključno s preskušanjem III. faze pri bolnikih z blago, zmerno ali hudo okvaro ledvic se je izpostavljenost pri hudi okvari ledvic povečala za približno 30 do 40 % v primerjavi z izpostavljenostjo, ugotovljeno pri sladkornih bolnikih tipa 2 z normalnim delovanjem ledvic.
In combination with other glucose-lowering medicinal products including basal insulin, when these, together with diet and exercise, do not provide adequate glycaemic control (see section 4.4 and 5.1 for available data on different combinations). 
V kombinaciji z drugimi zdravili za zniževanje glukoze, vključno z bazalnim insulinom, če ta zdravila skupaj z dieto in telesno dejavnostjo ne dosežejo ustrezne urejenosti glikemije (glejte poglavji 4.4 in 5.1 za podatke o različnih kombinacijah).
Talk to your doctor, nurse or pharmacist about how to inject Eperzan the right way. 
Posvetujte se z zdravnikom, medicinsko sestro ali farmacevtom o tem, kako pravilno injicirati zdravilo Eperzan.
Do not inject a double dose to make up for a forgotten dose. 
Ne injicirajte si dvojnega odmerka, če ste pozabili uporabiti prejšnji odmerek.
Remaining cartons must be stored at 2C to 8C until required. 
Preostale škatle je treba shranjevati pri temperaturi 2 °C do 8 °C do uporabe.
This can result in particles floating in the clear cartridge, not getting your full dose, or a blocked needle. 
To lahko povzroči, da v prozornem vložku plavajo delci, da ne dobite celotnega odmerka, ali da se igla zamaši.
There is no specific antidote for overdose with Eperzan. 
Specifičnega antidota za preveliko odmerjanje zdravila Eperzan ni.
Step 7 Prepare for injection 
7. korak Priprava za injiciranje
Background therapies in these studies included diet and exercise, metformin, sulphonylurea, thiazolidinedione, insulin glargine, or a combination of antidiabetic medicinal products. 
Osnovna zdravljenja v teh študijah so vključevala dieto in telesno dejavnost, metformin, sulfonilsečnino, tiazolidindion, insulin glargin ali kombinacijo antidiabetičnih zdravil.
Paediatric population: No pharmacokinetic data are available in paediatric patients. 
Farmakokinetičnih podatkov za pediatrične bolnike ni.
It is not known if albiglutide is excreted in human milk. 
Ni znano, ali se albiglutid izloča v materino mleko.
Viewing Window Number Window 
Opazovalno okence Številčno okence
The mean estimate of apparent volume of distribution of albiglutide following SC administration is 11 litres. 
Povprečni ocenjeni navidezni volumen porazdelitve albiglutida po subkutani uporabi je 11 litrov.
Otherwise, the pattern of adverse events was generally similar for antibody positive and negative patients. 
Sicer pa je bil vzorec neželenih učinkov na splošno podoben pri bolnikih s pozitivnim in negativnim izvidom protiteles.
Choose Injection Site 
Izberite mesto za injiciranje
Water for injections 
Vehikel: voda za injekcije
Step 1. 
1. korakom.
Once weekly. 
Enkrat na teden.
Experience in patients with severe renal impairment (<30 ml/min/1.73m2) or on dialysis is very limited and therefore Eperzan is not recommended in this population (see sections 4.4, 4.8, 5.1, 5.2). 
Izkušenj pri bolnikih s hudo okvaro ledvic (< 30 ml/min/1,73m2) in pri bolnikih na dializi je zelo malo, zato zdravilo Eperzan v tej populaciji ni priporočljivo (glejte poglavja 4.4, 4.8, 5.1 in 5.2).
During clinical studies of patients with type 2 diabetes, the highest dose of Eperzan administered was 100 mg subcutaneously every four weeks for 12 weeks. 
V kliničnih študijah pri bolnikih s sladkorno boleznijo tipa 2 je bil najvišji uporabljeni odmerek zdravila Eperzan 100 mg subkutano na štiri tedne 12 tednov.
6.6 Special precautions for disposal and other handling 
6.6 Posebni varnostni ukrepi za odstranjevanje in ravnanje z zdravilom Odlaganje
The clinical relevance of the observed thyroid C-cell tumours in rodents is unknown. 
Klinični pomen pri glodalcih opaženih tumorjev ščitničnih celic C ni znan.
9a Pull the needle out of your skin (Figure U). 
9a Potegnite iglo iz kože (Slika U).
Atrial fibrillation/flutter 
Atrijska fibrilacija/undulacija
The mean daily dose of insulin lispro at Week 26 was 31 IU, and at Week 52, 69% of patients treated with Eperzan were on 50 mg weekly. 
Povprečni dnevni odmerek insulina lispro 26. teden je bil 31 i.e. in 52. teden je 69 % bolnikov, zdravljenih z zdravilom Eperzan, prejemalo 50 mg na teden.
These types of gastrointestinal events may lead to dehydration, and worsen renal function. 
Ti učinki na prebavilih lahko povzročijo dehidracijo in poslabšajo delovanje ledvic.
Exposures at the 30 mg and 50 mg dose levels were consistent with a dose-proportional increase. 
Izpostavljenost pri odmerku 30 mg in 50 mg se je skladala z zvišanjem, sorazmernim odmerku.
Eperzan comes in a pen injector that you can inject yourself. 
Zdravilo Eperzan je na voljo v injekcijskem peresniku, ki si ga lahko injicirate sami.
Most patients with severe hypoglycaemic events in clinical studies were receiving concurrent sulphonylurea or insulin and none required hospitalisation or led to withdrawal of treatment. 
Večina bolnikov, ki so imeli v kliničnih študijah hude hipoglikemije, je sočasno prejemala sulfonilsečnino ali insulin; v nobenem od teh primerov ni bil potreben sprejem v bolnišnico in ni bilo treba opustiti zdravila.
Store in a refrigerator (between 2C and 8C). 
Shranjujte v hladilniku (med 2 °C in 8 °C).
Although most patients with injection site reactions were antibody negative (~85%), injection site reactions were reported more frequently for antibody positive (41%, N = 116) than antibody negative patients (14%, N = 1,927). 
Večina bolnikov, ki so imeli reakcije na mestu injiciranja, je sicer imela negativen izvid protiteles (~85 %), toda reakcije na mestu injiciranja so bile pri bolnikih s pozitivnim izvidom protiteles pogostejše (41 %, N = 116) kot pri tistih z negativnim izvidom (14 %, N = 1.927).
With the clear cartridge pointing up, gently swirl the pen for one minute. 
S prozornim vložkom obrnjenim navzgor previdno vrtite peresnik eno minuto.
Offspring of mice dosed with 50 mg/kg/day during organogenesis had reduced weight during the pre-weaning period (which recovered after weaning), dehydration and coldness, and a delay in balanopreputial separation. 
Mladiči miši, ki so prejemale 50 mg/kg/dan med obdobjem organogeneze, so imeli manjšo telesno maso pred odstavitvijo (ki se je popravila po odstavitvi), dehidriranost in hladnost ter zapoznelo balanoprepucijsko ločevanje.
Stop taking Eperzan and talk to your doctor straight away 
Nehajte uporabljati zdravilo Eperzan in se nemudoma posvetujte z zdravnikom.
When Eperzan is used in combination with insulin secretagogues (such as sulphonylureas) or insulin, patients should be advised to take precautions to avoid hypoglycaemia while driving and using machines (see section 4.4). 
Če je zdravilo Eperzan uporabljeno v kombinaciji z insulinskimi sekretagogi (kot so sulfonilsečnine) ali insulinom, je treba bolnikom naročiti, naj uporabijo previdnostne ukrepe, da se izognejo hipoglikemijam med vožnjo in upravljanjem s stroji (glejte poglavje 4.4).