natgillin/translations-raw huggingface dataset:
After eight days of repeated administration the reduction is about 85%. 
Po osmih dneh ponavljajoče se uporabe je zmanjšanje približno 85-odstotno.
A very small statistically significant but clinically irrelevant effect was found. 
Ugotovili so zelo majhen, statistično značilen, vendar klinično nepomemben učinek.
Your doctor will sometimes prescribe you a different dose and will tell you how long your treatment will last. 
Zdravnik vam bo včasih predpisal drugačen odmerek in vam povedal, koliko časa bo trajalo zdravljenje.
The clinical trials were all small, open and uncontrolled trials. 
Vsa klinična preskušanja so bila majhna, odprta in nekontrolirana prskušanja.
France sanofi-aventis 
Francija sanofi-aventis
In two of the studies, lansoprazole (formulation) was given immediately after a meal. 
V dveh izmed njih se je lansoprazol (formulacija) dajal neposredno po obroku.
Wyeth AB BOX 1822, 171 24 Solna, Sweden 
Wyeth AB BOX 1822, 171 24 Solna, Švedska
This medicine is available without prescription. 
To zdravilo je na voljo brez recepta.
Unless the applicant can show convincing data on satisfactory safety with the exposures obtained, it is recommended that a dose reduction of 50% is made. 
Razen če lahko vlagatelj pokaže prepričljive podatke o zadovoljivi varnosti pri doseženih izpostavljenostih, je priporočljivo upoštevati 50 % zmanjšanje odmerka.
4.2 Posology (in special populations) 
4.2 Odmerjanje (pri posebnih populacijah)
It is unlikely that the proposed vehicles, even if not of the same brand, would be of such pH and therefore affect the granule coating. 
Ni verjetno, da bi predlagani vehikli, tudi če niso iste blagovne znamke, imeli tako pH vrednost in bi posledično vplivali na oblogo zrnc.
Frequencies are defined as common (> 1/100, < 1/10); uncommon (> 1/1,000, < 1/100); rare (>1/10,000, <1/1,000); very rare (<1/10,000). 
Pogostnost neželenih učinkov je definirana kot: pogosti (> 1/100, < 1/10); občasni (> 1/1.000, < 1/100); redki (> 1/10.000, < 1/1.000); zelo redki (< 1/10.000).
In the third study, no effect of food was observed when the food was taken 30 minutes after administration. 
Pri tretji raziskavi niso opazili nobenega učinka hrane, če je bila ta zaužita 30 minut po dajanju zdravila.
However, prophylactic treatment should be recommended only for patients at high risk, see SPC for detailed proposal. 
Vendar pa se naj profilaktično zdravljenje priporoča le za bolnike z visokim tveganjem, za natančen predlog glejte SPC.
However, the magnitude of increase in exposure that is acceptable depends on the available clinical safety data available on the exposures. 
Vendar pa je sprejemljiva magnituda povečanja izpostavljenosti odvisna od razpoložljivih kliničnih varnostnih podatkov o izpostavljenosti.
Do not stop treatment early because your symptoms have got better. 
Zdravljenja ne prekinite predčasno, če se simptomi izboljšajo.
The pharmacokinetic data of children and adolescents are summarised under section 5.2. 
Farmakokinetični podatki za otroke in mladostnike so povzeti v poglavju 5.2.
H-1103 Budapest, Gyomroi ut 19-21 Hungary 
H-1103 Budimpešta, Gyomroi ut 19-21 Madžarska
52066 Aachen, Germany 
52066 Aachen, Nemčija
This might be attributed to high rates of metronidazole resistence. 
To bi bilo mogoče pripisati visokim stopnjam rezistence na metronidazol.
If you forget to take a dose, take it as soon as your remember unless it is nearly time for your next dose. 
Če pozabite vzeti odmerek, ga vzemite takoj, ko se spomnite, razen če je skoraj čas, ko bi morali vzeti naslednji odmerek.
Place the tablet on your tongue and suck gently. 
Tableto položite na jezik in nežno sesajte.
The factor that would influence the bioavailability the most would be if the granules were mixed with a vehicle of pH>7. 
Dejavnik, ki bi najbolj vplival na biološko uporabnost, bi nastopil, če bi bila zrnca zmešana z vehiklom s pH>7.
Medicines should not be disposed of via wastewater or household waste. 
Zdravil ne smete odstraniti v odpadne vode ali gospodinjske odpadke.
30,400 00040 Pomezia, Roma, Italy 
30,400 00040 Pomezia, Roma, Italija
The plasma protein binding is 97%. 
Vezava na beljakovine v plazmi je 97-odstotna.
In addition the CHMP identified the additional points to be harmonised in the various SPC sections. 
Nadalje je CHMP opredelil dodatne točke, ki jih je potrebno uskladiti v različnih poglavjih SPC.
Read all the information in this leaflet for guidance. 
Preberite vse podatke v tem navodilu za uporabo.
The clinical relevance of this is unknown. 
Klinični pomen tega ni znan.
Via Elio Vittorini 129 00144 Roma, Italy 
Via Elio Vittorini 129 00144 Roma, Italija
Although all treatments resulted in equivalent AUC of lansoprazole, it has to be noted that the studies were performed with certain brands of the different vehicles. 
Čeprav so vsa zdravljenja privedla do ekvivalentnega AUC lansoprazola, je treba omeniti, da so bile raziskave izvedene z določenimi blagovnimi znamkami različnih vehiklov.
If you take Agopton on a long-term basis (longer than 1 year) your doctor will probably keep you under regular surveillance. 
Če boste zdravilo Agopton jemali daljši čas (več kot 1 leto), vas bo zdravnik verjetno redno pregledoval.
If the required daily dose exceeds 120 mg, it should be given in two divided doses. 
Če potrebni dnevni odmerek presega 120 mg, ga je treba razdeliti v dva odmerka.
Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. 
Obvestite svojega zdravnika, če jemljete ali ste pred kratkim jemali katero koli zdravilo, tudi če ste ga dobili brez recepta.
The effects of overdose on lansoprazole in humans are not known (although the acute toxicity is likely to be low) and, consequently, instruction for treatment cannot be given. 
Učinki prevelikega odmerjanja lansoprazola pri človeku niso znani (čeprav je akutna toksičnost verjetno majhna), zato ni mogoče dati navodil za zdravljenje.
The manufacturer is: <{Name and address}> <{tel}> <{fax}> <{e-mail}> 
Izdelovalec: <{Ime in naslov}> <{tel.}> <{faks}> <{e-pošta}> [Izpolni država članica.]
Furthermore, at both timepoints, there was a trend for better efficacy of the 30 mg dose. 
Nadalje je bilo ob obeh časih vrednotenja mogoče zaznati trend večje učinkovitosti 30 mg odmerka.
Taking Agopton with food and drink 
Jemanje zdravila Agopton skupaj s hrano in pijačo
As regards the relief of symptoms, this was examined in both studies through the use of diary cards and investigator interviews. 
Kar se tiče lajšanja simptomov, so ga pri obeh raziskavah preverjali s pomočjo dnevnikov in intervjujev raziskovalcev.
Treatment will usually be every day for 7 days. 
Zdravljenje ponavadi traja 7 dni vsak dan.
Also contains lactose and aspartame. 
Vsebuje tudi laktozo in aspartam.
Your condition may not have been fully healed and may reoccur if you do not finish your course of treatment. 
Bolezen morda še ni povsem pozdravljena in se lahko ponovi, če ne dokončate zdravljenja.
Do not crush or chew these capsules or the content of an emptied capsule because this will stop them from working properly. 
Kapsul ali njihove vsebine ne zdrobite in jih ne žvečite, ker bo to preprečilo pravilno delovanje.
A daily dose of 30 mg should not be exceeded in the elderly unless there are compelling clinical indications. 
Dnevni odmerek 30 mg se pri starejših bolnikih ne sme preseči, razen kadar obstajajo nujne klinične indikacije.
This is also reflected in the SPC for lansoprazole. 
To je razvidno tudi iz SPC za lansoprazol.
This is reflected in the SPC. 
To je razvidno v SPC.
[To be completed nationally - Statement and phone number to be inserted based on national requirement for information on a toxicological service.] 
[Izpolni država članica - Izjavo in telefonsko številko vnesite glede na lokalne zahteve o informacijah o toksikološki službi.]
Agopton should not be given to children. 
Zdravilo Agopton se ne sme dajati otrokom.
If you are taking Agopton once a day, try to take it at the same time each day. 
Če zdravilo Agopton jemljete enkrat na dan, ga poskusite jemati vsak dan ob istem času.
The doctor may have to adjust your dosage. 
Morda vam bo moral prilagoditi odmerek.
• the Summary of Products Characteristic, Labelling and Package Leaflet proposed by the Marketing Authorisation Holders has been assessed based on the documentation submitted and the scientific discussion within the Committee, 
• Povzetek glavnih značilnosti zdravila, označevanje in Navodila za uporabo, ki jih je predlagalo podjetje, so bili ocenjeni na podlagi predložene dokumentacije in znanstvene razprave v okviru odbora,
• Symptomatic gastroesophageal reflux disease (4.1 and 4.2) 
• Simptomatska gastroezofagealna refluksna bolezen (4.1 in 4.2)
Agopton should be taken at least 30 minutes before food (see section 5.2). 
Zdravilo Agopton je treba jemati vsaj 30 minut pred obrokom (glejte poglavje 5.2).
Further reductions are not practically possible and data may not allow simulations of PK/PD regarding the increase the dose-interval. 
Nadaljnja zmanjšanja praktično niso možna in podatki morda ne dopuščajo simulacije farmakokinetike/farmakodinamike v zvezi s povečanjem odmernega intervala.
Relief of symptoms is obtained rapidly. 
Simptomi se hitro ublažijo.
• 4.5 Interaction with other medicinal products and other forms of interaction 
• 4.5 Medsebojno delovanje z drugimi zdravili in druge oblike interakcij
One study of the interaction with phenytoin has been submitted. 
Predložena je bila ena raziskava o interakciji s fenitoinom.
• Food interaction 
• Medsebojno delovanje s hrano
To give your medicine the best chance of working, take it at the right time and do not miss a dose. 
Da bi zdravilo najbolje delovalo, ga vzemite ob ustreznem času in ne izpustite odmerka.
Almirall Prodesfarma, S.A. General Mitre, 151 08022 -Barcelona, Spain 
Almirall Prodesfarma, S.A. General Mitre, 151 08022 Barcelona, Španija
The treatment duration is most commonly 7 days but sometimes up to 14 days. 
Zdravljenje najpogosteje traja 7 dni, včasih pa tudi do 14 dni.
It was agreed that the indication should only mention “symptomatic gastroesophageal reflux disease”. 
Dogovorjeno je bilo, naj indikacija omenja zgolj »simptomatsko gastroezofagealno refluksno bolezen«.
Because of limited safety data for patients on maintenance treatment for longer than 1 year, regular review of the treatment and a thorough risk/benefit assessment should regularly be performed in these patients. 
Zaradi omejenih podatkov o varnosti bolnikov na vzdrževalnem zdravljenju, ki traja dlje kot eno leto, je treba redno preverjati zdravljenje ter temeljito oceniti tveganje in koristi.
The usual doses of Agopton for adults are given below. 
Običajni odmerki zdravila Agopton za odrasle so navedeni spodaj.
Benefit/Risk consideration 
Ocenjevanje razmerja med koristmi in tveganji
OVERALL SUMMARY OF THE SCIENTIFIC EVALUATION OF AGOPTON AND ASSOCIATED NAMES 
SPLOŠNI POVZETEK ZNANSTVENEGA VREDNOTENJA ZDRAVILA AGOPTON IN Z NJIM POVEZANIH IMEN
The submitted data for the indication “symptomatic gastroesophageal reflux disease” support this the indication. 
Predloženi podatki za indikacijo »simptomatska gastroezofagealna refluksna bolezen« podpirajo to indikacijo.
Also contains sucrose and mannitol (E421). 
Vsebuje tudi saharozo in manitol (E 421).
The evaluation of the symptoms yielded less clear results than for the healing of the ulceration, and the results are inconsistent across the different symptoms/parameters and methods used to assess the symptoms. 
Vrednotenje simptomov je podalo manj jasne rezultate kot zdravljenje razjed, rezultati pa pri vrednotenju različnih simptomov oz. parametrov ter metod, uporabljenih za oceno simptomov, niso konsistentni.
A study has shown that co-administration of lansoprazole (60 mg once daily) with atazanavir 400 mg to healthy volunteers resulted in a substantial reduction in atazanavir exposure (approximately 90% decrease in AUC and Cmax). 
Študija je pokazala, da je sočasna uporaba lansoprazola (60 mg enkrat na dan) in atazanavira 400 mg pri zdravih prostovoljcih povzročila pomembno zmanjšanje izpostavljenosti atazanaviru (približno 90odstotno zmanjšanje vrednosti AUC in Cmax).
Seber Portuguesa Farmaceutica, SA Rua Norberto de Oliveira,1a 5 2675-130 Povoa de Santo Adriao, Portugal 
Seber Portuguesa Farmaceutica, SA Rua Norberto de Oliveira,1a 5 2675-130 Povoa de Santo Adriao, Portugalska
A blood test will be taken to check possible reduction of white blood cells (agranulocytosis). 
Opravil bo krvno preiskavo, s katero bo preveril, ali je prisotno zmanjšanje števila belih krvničk (agranulocitoza).
Colitis, stomatitis 
Kolitis, stomatitis
A decision on whether to continue/discontinue breast-feeding or to continue/discontinue therapy with lansoprazole should be made taking into account the benefit of breastfeeding to the child and the benefit of lansoprazole therapy to the woman. 
Pri odločitvi, ali nadaljevati ali prekiniti dojenje oziroma ali nadaljevati ali prekiniti zdravljenje z lansoprazolom, je treba upoštevati korist dojenja za otroka in korist zdravljenja z lansoprazolom za žensko.
• the scope of the referral was the harmonisation of the Summary of Products Characteristics, 
• Namen napotitve je bil usklajevanje Povzetkov glavnih značilnosti zdravila,
For the best results from your medicines you should take Agopton at least 30 minutes before food. 
Za najboljše rezultate morate zdravilo Agopton jemati vsaj 30 minut pred obrokom.
While the results for the two doses of lansoprazole and for misoprostol are very similar, all three treatments were markedly better than placebo and this is confirmed by statistical analysis (p<0.001 for each active vs. placebo comparison). 
Medtem ko so bili rezultati za oba odmerka lansoprazola in misoprostol zelo podobni, so se vsi trije načini zdravljenja odrezali bistveno bolje od placeba, kar potrjuje statistična analiza (p<0,001 za vsako učinkovino v primerjavi s placebom).
Based on the documentation submitted by the MAH and the scientific discussion within the Committee, the CHMP considered that the benefit/risk ratio of Agopton and associated names is favourable for use relating to: 
Na podlagi dokumentacije, ki jo je predložil imetnik dovoljenja za promet z zdravilom, ter znanstvene razprave v okviru Odbora je CHMP menil, da je razmerje med tveganji in koristmi za zdravilo Agopton in z njim povezana imena ugodno za uporabo v zvezi z:
Lansoprazole has not been marketed for use in children or adolescents in the EU. 
Lansoprazol v EU nima dovoljenja za promet za uporabo pri otrocih ali mladostnikih.
Patients with moderate or severe liver disease should be kept under regular supervision and a 50% reduction of the daily dose is recommended (see section 4.4 and 5.2). 
Bolnike z zmerno do hudo boleznijo jeter je treba redno nadzorovati, priporoča pa se 50-odstotno zmanjšanje dnevnega odmerka (glejte poglavji 4.4 in 5.2).
Due to the fact that Agopton and associated names (lansoprazole) does not have the same Summary of Product Characteristics (SPC) in the various Member States in the European Union as a result of divergent national decisions, a harmonisation of the SPC for Agopton and associated names, throughout Europe has become necessary. 
Z ozirom na dejstvo, da zdravilo Agopton in z njim povezana imena (lansoprazol) v različnih državah članicah EU nima istega Povzetka glavnih značilnosti zdravila (SPC), kar je posledica razhajajočih se nacionalnih odločitev, je prišlo do potrebe po uskladitvi SPC za zdravilo Agopton in z njim povezana imena po celotni Evropi.
The overall relief of the primary symptoms (epigastric pain and heartburn) were assessed. 
Ocenjeno je bilo splošno lajšanje primarnih simptomov (epigastrična bolečina in zgaga).
The recommended dose should be 15-30 mg o.d. with recommendations regarding further investigation, should the patient not respond within 4 weeks. 
Priporočeni odmerek naj bo 15 do 30 mg enkrat dnevno, s priporočilom za nadaljnje preiskave, če se bolnik ne odzove v roku 4 tednov.
Laboratoires TAKEDA SA 15, quai de Dion Bouton 92816 Puteaux cedex, France 
Laboratoires TAKEDA SA 15, quai de Dion Bouton 92816 Puteaux cedex, Francija
Increase in liver enzyme levels 
Zvišane ravni jetrnih encimov
Directions for re-constituting suspension from sachets: 
Navodila za rekonstitucijo suspenzije iz vrečic:
46 quai de la Papee 75601 Paris Cedex 12, France 
46 quai de la Papee 75601 Paris Cedex 12, Francija
Higher exposure for lansoprazole was also seen in newborns and babies up to an age of approx. 10 weeks. 
Višja izpostavljenost lansoprazolu je bila opažena tudi pri novorojenčkih in dojenčkih starosti do približno 10 tednov.
The contents of one sachet should be reconstituted by stirring into 30 ml (two tablespoons) of tap water, and swallowed immediately. 
Vsebino ene vrečice je treba rekonstituirati tako, da jo vmešate v 30 ml (dve žlici) vode in takoj pogoltnete.
However, the pharmacokinetic and pharmacodynamic data as well as clinical data for the use of lansoprazole in children are available in the literature. 
Vendar pa so v literaturi na voljo farmakokinetični in farmakodinamični podatki, kakor tudi klinični podatki za uporabo lansoprazola pri otrocih.
Capsules should be swallowed whole with liquid. 
Kapsule je treba pogoltniti cele, s tekočino.
The CHMP agrees that no information regarding the lansoprazole effects on phenytoin or carbamazepine is needed in the SPC. 
CHMP se strinja, da v SPC ni potrebno navesti nobene informacije v zvezi z vplivom lansoprazola na fenitoin ali karbamazepín.
Steven-Johnson syndrome, toxic epidermal necrolysis 
Steven-Johnsonov sindrom, toksična epidermalna nekroliza
The following side effects are very rare (occur in less than 1 in 10000 patients): - severe hypersensitivity reactions including shock. 
Naslednji neželeni učinki so zelo redki (pojavijo se pri manj kot 1 bolniku od 10.000): - hude preobčutljivostne reakcije, vključno s šokom.
No clinically significant interactions of lansoprazole with nonsteroidal anti-inflammatory drugs have been demonstrated, although no formal interactions studies have been performed. 
Klinično pomembnih interakcij med lansoprazolom in nesteroidnimi antirevmatiki niso ugotovili, vendar formalnih študij interakcij niso opravili.
However, at 4 weeks, the efficacy of the 15 mg dose was less than for the comparator at 8 weeks. 
Vendar pa je bila učinkovitost 15 mg odmerka pri 4 tednih manjša od učinkovitosti primerjalnega zdravila pri 8 tednih.
CYP2C19 is subject to genetic polymorphism and 2-6 % of the population, called poor metabolisers (PMs), are homozygote for a mutant CYP2C19 allele and therefore lacks a functional CYP2C19 enzyme. 
CYP2C19 je izpostavljen genetskemu polimorfizmu in 2-6 % populacije, t. i. bolniki s počasno presnovo (PM - Poor Metaboliser) so homozigoti za mutantni alel CYP2C19 in zato nimajo funkcionalnega encima CYP2C19.
It may be suitable for those who are unable to take clarithromycin as part of an eradication therapy, when local resistance rates to metronidazole are low. 
Utegne pa biti primeren za tiste, ki v okviru eradikacijskega zdravljenja ne morejo jemati klaritromicina, če so lokalne stopnje rezistence na metronidazol nizke.
In conclusion, the efficacy data are considered too weak to support a paediatric indication of oesophagitis in children and adolescents. 
Tako so podatki glede učinkovitosti ocenjeni kot prešibki, da bi podpirali pediatrično indikacijo za ezofagitis pri otrocih in mladostnikih.
Caution is advised when combining the two drugs. 
Pri kombiniranju teh dveh zdravil se priporoča previdnost.
If the symptoms are not relieved within 4 weeks with a daily dose of 30 mg, further examinations are recommended. 
Če se simptomi ne ublažijo v 4 tednih zdravljenja z odmerkom 30 mg na dan, se priporočajo nadaljnje preiskave.
If you are pregnant, breast-feeding or if there is a chance you might be pregnant ask your doctor for advice before taking this medicine. 
Če ste noseči, dojite ali če obstaja verjetnost, da ste noseči, se pred začetkom jemanja tega zdravila posvetujte z zdravnikom.
Insomnia, hallucination, confusion 
Insomnija, halucinacije, konfuznost
Hepatitis, jaundice 
Hepatitis, zlatenica
Different disease concepts for “symptomatic gastroesophageal reflux disease” and other “functional diseases” e.g. “dyspepsia”, are established throughout Europe and reflected in different labelling. 
Po Evropi so uveljavljena različna tolmačenja za »simptomatsko gastroezofagealno refluksno bolezen« in druge »funkcionalne bolezni«, npr. dispepsijo«, kar se odraža v različnem označevanju.
- very rarely Agopton may cause a reduction in the number of white blood cells and your resistance to infection may be decreased. 
- Zdravilo Agopton lahko zelo redko povzroči zmanjšanje števila belih krvničk, kar lahko zmanjša odpornost na okužbe.
When selecting appropriate combination therapy consideration should be given to official local guidance regarding bacterial resistance, duration of treatment, (most commonly 7 days but sometimes up to 14 days) and appropriate use of antibacterial agents. 
Pri iskanju ustreznega kombiniranega zdravljenja je treba upoštevati uradne lokalne smernice glede bakterijske rezistence, trajanja zdravljenja (najpogosteje 7 dni, vendar včasih 14 dni) in ustrezne uporabe antibiotikov.
The proportion remaining healed at 12 months in evaluable patients was 39% on placebo vs. 84 % on lansoprazole15 mg maintenance. 
Delež ocenjevanih bolnikov, ki so ostali zdravi po 12 mesecih, je znašal 39 % pri placebu v primerjavi s 84 % za lansoprazol 15 mg kot vzdrževalno zdravljenje.
Effects of other drugs on lansoprazole 
Učinki drugih zdravil na lansoprazol
John Wyeth & Brother Limited Trading as Wyeth Pharmaceuticals Huntercombe Lane South Taplow, Maidenhead Berkshire SL6 0PH UK 
John Wyeth & Brother Limited Trading as Wyeth Pharmaceuticals Huntercombe Lane South Taplow, Maidenhead Berkshire SL6 0PH Velika Britanija
• Dosage recommendation for the eradication of H. pylori differences: inclusion of specific recommendations on the antibiotics to be used 
• Razlike v priporočilu za odmerjanje za eradikacijo H. pylori: Vključitev specifičnih priporočil za antibiotike, ki se naj uporabljajo
However, higher values for exposure will be expected in children below 1 year of age with the pharmaceutical forms that are commercially available. 
Vendar pa se pri otrocih, starih manj kot eno leto, ob uporabi komercialno dosegljivih farmacevtskih oblik pričakujejo višje vrednosti izpostavljenosti.
Germany (referring Member State) identified the following issues, each affecting several sections of the SPC. 
Nemčija (referenčna država članica) je opredelila v nadaljevanju naštete vidike, od katerih se vsak tiče več poglavij Povzetka glavnih značilnosti zdravila (SPC).
However the trial design and the results of the studies were not adequate to recommend the use of lansoprazole in for the treatment of oesophagitis in children. 
Vendar pa zasnova raziskav in rezultati niso bili ustrezni, da bi bilo mogoče priporočiti uporabo lansoprazola za zdravljenje ezofagitisa pri otrocih.
15 mg once daily. 
15 mg enkrat na dan.
This medicinal product is authorised in the Member States of the EEA under the following names: 
Zdravilo je pridobilo dovoljenje za promet v državah članicah EGP pod naslednjimi imeni: Irska:
In the case of suspected overdose the patient should be monitored. 
Če se sumi na preveliko odmerjanje, mora biti bolnik pod nadzorom.
Your doctor may perform or have performed an additional investigation called an endoscopy in order to diagnose your condition and/or exclude malignant disease. 
Zdravnik bo morda opravil ali pa je opravil dodatno preiskavo, imenovano endoskopija, da bi ugotovil, katero bolezen imate ali izključil možnost raka ali oboje.
As short-term antisecretory treatment combined with eradication therapy is known to be associated with significantly improved healing rates over antisecretory treatment alone, testing for and eradication of H. pylori would be considered mandatory. 
Glede na to, da je znano, da je kratkoročno antisekretorno zdravljenje v kombinaciji z eradikacijskim zdravljenjem povezano s pomembno izboljšanimi stopnjami celjenja v primerjavi z zgolj antisekretornim zdravljenjem, bi morala biti testiranje za H. pylori in eradikacija obvezna.