natgillin/translations-raw huggingface dataset:
Hyperprolactina emia decreases in total T4 decreases in free T4 decreases in total T3 increases in TSH 
Bolezni endokrinega sistema hiperprolaktine mija,15, znižanje celotnega T4 znižanje prostega T4 znižanje celotnega T3 zvišanje TSH 24
• Seroquel can be taken with or without food. 
• Zdravilo Seroquel lahko vzamete s hrano ali brez.
This is because the combined effect of Seroquel XR and alcohol can make you sleepy. 
Skupen učinek zdravila Seroquel SR in alkohola lahko povzroči zaspanost.
Changes in thyroid function tests have also been observed in children and adolescents. 
Pri otrocih in mladostnikih so opazili tudi spremembe v preiskavah delovanja ščitnice.
Concomitant use of quetiapine and thioridazine caused an increased clearance of quetiapine with approx. 70%. 
Pri sočasni uporabi kvetiapina in tioridazina se poveča očistek kvetiapina za približno 70 %.
As with other antipsychotics and antidepressants, Seroquel XR should be used with caution in the elderly, especially during the initial dosing period. 
Tako kot druga antipsihotična in antidepresivna zdravila je potrebno zdravilo Seroquel SR pri starejših bolnikih uporabljati previdno, še posebej v začetnem obdobju uporabe.
Seroquel XR 150 mg and 300 mg/day, given as add-on treatment to ongoing antidepressant therapy (amitriptyline, bupropion, citalopram, duloxetine, escitalopram, fluoxetine, paroxetine, sertraline or venlafaxine) demonstrated superiority over antidepressant therapy alone in reducing depressive symptoms as measured by improvement in MADRS total score (LS mean change vs. placebo of 2-3.3 points). 
Seroquel SR 150 mg in 300 mg/dan kot dodatek že potekajočemu antidepresivnemu zdravljenju (amitriptilin, bupropion, citalopram, duloksetin, escitalopram, fluoksetin, paroksetin, sertralin ali venlafaksin) je v primerjavi z antidepresivno terapijo samo superiorno zmanjšal depresivne simptome; kot merilo je bilo uporabljeno izboljšanje celotnega seštevka po MADRS
Extrapyramidal symptoms3, 4 
Bolezni živčevja ekstrapiramidni simptomi3, 4
Renal impairment: Dosage adjustment is not necessary in patients with renal impairment. 
Okvara ledvic: Pri bolnikih z okvaro ledvic prilagoditev odmerka ni potrebna.
The effect size of the 600 mg and 800 mg doses was greater than that of the 400 mg dose. 
Učinek 600-mg in 800-mg odmerka je bil večji kot
Venous Thromboembolism (VTE) 
Venska tromboembolija (VTE)
Steady-state peak molar concentrations of the active metabolite norquetiapine are 35% of that observed for quetiapine. 
Koncentracija v ravnotežnem stanju aktivnega metabolita norkvetiapina je 35 % delež koncentracije opažene pri kvetiapinu.
Pharmacokinetic data were sampled in 9 children aged 10-12 years old and 12 adolescents, who were on steady-state treatment with 400 mg quetiapine twice daily. 
Farmakokinetični podatki so bili zbrani pri 9 otrocih, starih od 10 do 12 let, in pri 12 mladostnikih, ki so dobivali 400 mg kvetiapina dvakrat na dan in so bili s tem zdravljenjem v stanju dinamičnega ravnovesja.
• Combination of fever, flu-like symptoms, sore throat, or any other infection with very low white blood cell count, a condition called agranulocytosis. 
• kombinacija zvišane telesne temperature, gripi podobnih simptomov, vnetega žrela ali kakšne druge okužbe z zelo majhnim številom belih krvnih celic (stanje imenovano agranulocitoza),
For more convenient dosing, patients who are currently being treated with divided doses of immediate release Seroquel tablets may be switched to Seroquel XR at the equivalent total daily dose taken once daily. 
Za enostavnejše odmerjanje lahko bolniki, ki trenutno dobivajo deljene odmerke tablet Seroquel filmsko obložene tablete, preidejo na zdravilo Seroquel SR v enakem celotnem dnevnem odmerku, ki ga vzamejo enkrat na dan. Potrebne utegnejo biti individualne prilagoditve odmerka.
Prior to initiating treatment, clinicians should consider the safety profile of SEROQUEL XR (see Section 
Pred uvedbo zdravljenja mora zdravnik upoštevati varnostne značilnosti zdravila Seroquel SR (glejte poglavje 4.4).
Such patients should have a WBC count and an absolute neutrophil count (ANC) performed promptly, especially in the absence of predisposing factors. 
Takšnim bolnikom je treba takoj določiti število belih krvnih celic in absolutno število nevtrofilcev, zlasti če nimajo predispozicijskih dejavnikov.
8 tablets 
8 tablet
Your tablets may make you feel sleepy. 
Tablete Seroquel lahko povzročijo zaspanost.
In a study examining the effects of food on the bioavailability of quetiapine, a high-fat meal was found to produce statistically significant increases in the Seroquel XR Cmax and AUC of approximately 50% and 20% respectively., It cannot be excluded that the effect of a high fat meal on the formulation may be larger. 
V študiji, ki je preučevala učinke hrane na biološko uporabnost kvetiapina, so odkrili, da zelo masten obrok povzroči statistično značilno povečanje Cmax in AUC zdravila Seroquel SR za približno 50 % oziroma 20 %.
No information is available for Seroquel XR in children and adolescents. 
O zdravilu Seroquel SR pri otrocih in mladostnikih ni informacij.
There have been reports of agitation, hypertonia, hypotonia, tremor, somnolence, respiratory distress, or feeding disorder. 
hipertoniji, hipotoniji, tremorju, zaspanosti, dihalni stiski in motnjah hranjenja.
Treatment with Seroquel was initiated at 50 mg/day and on day 2 increased to 100 mg/day; subsequently the dose was titrated to a target dose (mania 400-600 mg/day; schizophrenia 400-800 mg/day) using increments of 100 mg/day given two or three times daily. 
Zdravljenje z zdravilom Seroquel so začeli s 50 mg na dan; odmerek so nato 2. dan povečali na 100 mg na dan, potem pa so odmerek titrirali do ciljnega odmerka (manija od 400 do 600 mg na dan, shizofrenija od 400 do 800 mg na dan) v korakih po 100 mg na dan in z uporabo dvakrat ali trikrat na dan.
50 mg tablets are peach coloured; 150 mg tablets are white coloured, 200 mg tablets are yellow coloured; 300 mg tablets are pale yellow coloured and 400 mg tablets are white coloured. 
50 mg tablete so marelične barve; 150 mg tablete so bele barve; 200 mg tablete so rumene barve,
• You, or someone in your family, have or have had any heart problems, for example heart rhythm problems, weakening of the heart muscle or inflammation of the heart or if you are taking any medicines that may have an impact on the way your heart beats. 
• imate ali ste imeli vi ali kdo v vaši družini težave s srcem, na primer motnje srčnega ritma,
What Seroquel is and what it is used for What you need to know before you take Seroquel How to take Seroquel 
Kaj je zdravilo Seroquel in za kaj ga uporabljamo Kaj morate vedeti, preden boste vzeli zdravilo Seroquel Kako jemati zdravilo Seroquel
The tablets should be swallowed whole and not split, chewed or crushed. 
Bolnik mora tablete s podaljšanim sproščanjem pogoltniti cele in jih ne sme lomiti, žvečiti ali drobiti.
If you are, Seroquel should not be taken because the group of medicines that Seroquel belongs to may increase the risk of stroke, or in some cases the risk of death, in elderly people with dementia. 
Če ste, ne smete jemati zdravila Seroquel, kajti skupina zdravil, v katero spada Seroquel, lahko starejšim osebam z demenco poveča tveganje možganske kapi in v nekaterih primerih tveganje smrti.
Cardiomyopathy and myocarditis have been reported in clinical trials and during the post-marketing experience, however, a causal relationship to quetiapine has not been established. 
V kliničnih preskušanjih in med obdobjem po prihodu zdravila na trg so poročali o kardiomiopatiji in miokarditisu, a vzročna povezanost s kvetiapinom ni bila ugotovljena.
Dizziness 4, 16, 
Bolezni živčevja omotica 4, 16,
Quetiapine does not produce dopamine D2-receptor supersensitivity after chronic administration. 
Kvetiapin po kronični uporabi ne povzroči supersenzitivnosti dopaminskih receptorjev D2.
Other medicines and Seroquel Tell your doctor if you are taking or have recently taken any other medicines . 
Obvestite zdravnika ali farmacevta, če jemljete, ste pred kratkim jemali ali pa boste morda začeli jemati katero koli drugo zdravilo.
In one long-term study (up to 2 years treatment) evaluating recurrence prevention in patients with manic, depressed or mixed mood episodes quetiapine was superior to placebo in increasing the time to recurrence of any mood event (manic, mixed or depressed), in patients with bipolar I disorder. 
V eni dolgoročni študiji (do 2 leti zdravljenja), ki je ocenjevala preprečevanje recidivov pri bolnikih z maničnimi, depresivnimi ali mešanimi razpoloženjskimi epizodami, je bil kvetiapin pri bolnikih z bipolarno motnjo I superioren nad placebom, kar zadeva čas do recidiva kateregakoli razpoloženjskega dogodka (maničnega, mešanega ali depresivnega).
The percentage of quetiapine treated patients who gained ≥7% of body weight ranged from 5.3% for the 50 mg daily dose to 15.5% for the 400 mg daily dose (with lower gain for the 600 and 800 mg daily doses), compared to 3.7% for placebo treated patients. 
Odstotek bolnikov, ki so prejemali kvetiapin in se jim je telesna masa povečala za ≥ 7 %, je segal od 5,3 % z dnevnim odmerkom 50 mg do 15,5 % z dnevnim odmerkom 400 mg (z manjšim povečanjem z dnevnima odmerkoma 600 mg in 800 mg); pri bolnikih, ki so prejemali placebo, je bilo to povečanje 3,7 %.
The class of medicines to which Seroquel belongs can cause heart rhythm problems, which can be serious and in severe cases may be fatal. 
Skupina zdravil, v katero spada zdravilo Seroquel, lahko povzroči motnje srčnega ritma, ki so lahko resne in v nekaterih hudih primerih tudi smrtne.
In the 6 week active-controlled switching study the primary outcome variable was the proportion of patients who showed lack of efficacy, ie, who discontinued study treatment due to lack of efficacy or whose PANSS total score increased 20% or more from randomization to any visit. 
pri katerih učinkovitost ni bila zadostna, tj. bolnikov, ki so študijo zaradi nezadostne učinkovitosti prekinili ali pri katerih se je celotni seštevek po PANSS v primerjavi z randomizacijo na kateremkoli pregledu povečal za 20 % ali več.
Weight gain has been reported in patients who have been treated with quetiapine, and should be monitored and managed as clinically appropriate as in accordance with utilized antipsychotic guidelines (See Sections 4.8 and 5.1). 
Zato je te bolnike treba kontrolirati in jih voditi, kot je klinično primerno in v skladu z uporabljanimi smernicami za antipsihotike (glejte poglavji 4.8 in 5.1).
Cellulose, microcrystalline Sodium citrate Lactose monohydrate Magnesium stearate Hypromellose 2208 
Jedro mikrokristalna celuloza natrijev citrat laktoza monohidrat magnezijev stearat hipromeloza 2208
In placebo-controlled studies in elderly patients with dementia-related psychosis, the incidence of cerebrovascular adverse events per 100 patient years was not higher in quetiapine-treated patients than in placebo-treated patients. 
V študijah, kontroliranih s placebom, pri starejših bolnikih s psihozo, povezano z demenco, incidenca možgansko-žilnih neželenih učinkov na 100 bolnikovih let med bolniki, ki so dobivali kvetiapin, ni bila višja, kot v skupini s placebom.
Neither low dose (400 mg/day) nor high dose regimen (800 mg/day) quetiapine was superior to placebo with respect to the percentage of patients achieving response, defined as ≥30% reduction from baseline in PANSS total score. 
Ne shema z nižjim odmerkom (400 mg/dan) ne shema z višjim odmerkom (800 mg/dan) kvetiapina nista bili boljši od placeba, kar zadeva odstotek bolnikov, ki so dosegli odziv (odziv je bil opredeljen kot ≥ 30 % zmanjšanje celotnega seštevka PANSS v primerjavi z izhodiščem).
The reduction in total and free T 4 was maximal within the first six weeks of quetiapine treatment, with no further reduction during long-term treatment. 
Znižanje celotnega in prostega T 4 je bilo največje v prvih šestih tednih zdravljenja s kvetiapinom.
• Inflammation of the liver (hepatitis). 
• vnetje jeter (hepatitis),
• High blood pressure medicines. 
• zvišan krvni tlak.
(See section 4.5). 
(glejte poglavje 4.5).
Pharmacokinetic data were sampled in 9 children aged 10-12 years old and 12 adolescents, who were on steady-state treatment with 400 mg quetiapine (Seroquel) twice daily. 
Farmakokinetični podatki so bili zbrani pri 9 otrocih, starih od 10 do 12 let, in pri 12 mladostnikih, ki so dobivali 400 mg kvetiapina (zdravilo Seroquel) dvakrat na dan in so bili s tem zdravljenjem v stanju dinamičnega ravnovesja.
At steady-state, the dose-normalised plasma levels of the parent compound, quetiapine, in children and adolescents (10-17 years of age) were in general similar to adults, though Cmax in children was at the higher end of the range observed in adults. 
Za odmerek normalizirana koncentracija matične spojine, kvetiapina, je bila v stanju dinamičnega ravnovesja pri otrocih in mladostnikih (starih od 10 do 17 let) na splošno podobna kot pri odraslih, toda Cmax je bila pri otrocih v zgornjem delu razpona, ugotovljenega pri odraslih.
(1) See Section 4.4. 
(1) Glejte poglavje 4.4.
(patients <18 years of age) on at least one occasion. 
mmol/l) (bolniki, stari < 18 let) vsaj v enem primeru.
Combined pack 
(kombinirano pakiranje)
For patients who were randomized to placebo, the mean weight gain during the open label period was 2.39 kg, and by week 48 of the randomized period the mean weight gain was 0.89 kg, compared to open label baseline. 
Pri bolnikih, randomiziranih na placebo, je bilo povprečno povečanje telesne mase med odprtim obdobjem 2,39 kg, do 48. tedna randomiziranega obdobja pa je bilo povprečno povečanje telesne mase 0,89 kg v primerjavi z izhodiščem odprtega obdobja.
In addition, a higher percentage of patients treated in the lithium add-on group (8.0%) had weight gain (≥7%) at the end of treatment compared to patients in the placebo add-on group (4.7%). 
Poleg tega je bil ob koncu zdravljenja delež povečanja telesne mase (≥ 7 %) v skupini z dodatkom litija večji (8,0 %) kot v skupini z dodatkom placeba (4,7 %).
The class of medicines to which Seroquel XR belongs can cause heart rhythm problems, which can be serious and in severe cases may be fatal. 
Skupina zdravil, v katero spada zdravilo Seroquel SR, lahko povzroči motnje srčnega ritma, ki so lahko resne in v nekaterih hudih primerih tudi smrtne.
TRADE NAME 
LASTNIŠKO IME
The 50 mg, 200 mg and 300 mg tablets also contain iron oxide yellow (E172) and the 50 mg tablets contain iron oxide red (E172). 
50-mg, 200-mg in 300-mg tablete vsebujejo tudi rumen železov oksid (E172) in 50- mg tablete vsebujejo rdeč železov oksid (E172).
Tablet Strength 
Jakost tablet
In the mania study, the difference in LS mean change from baseline in YMRS total score (active minus placebo) was -5.21 for Seroquel 400 mg/day and -6.56 for Seroquel 600 mg/day. 
V študiji manije je bila razlika v povprečni spremembi po metodi najmanjših kvadratov celotnega seštevka YMRS v primerjavi z izhodiščem (učinkovina minus placebo) -5,21 za Seroquel 400 mg/dan in -6,56 za Seroquel 600 mg/dan.
Elderly patients should be started on 50 mg/day. 
Pri starejših bolnikih je treba zdravljenje začeti s 50 mg/dan.
Liver problems If you have liver problems your doctor may change your dose. 
Če imate težave z jetri, vam zdravnik lahko spremeni vaš odmerek.
Tablet core: microcrystalline cellulose, sodium citrate, lactose monohydrate, magnesium stearate, hypromellose. 
Jedro tablete: mikrokristalna celuloza, natrijev citrat, laktoza monohidrat, magnezijev stearat, hipromeloza.
Uncommon Rare 
Zelo redki
Like all medicines, Seroquel can cause side effects, although not everybody gets them. 
Kot vsa zdravila ima lahko tudi to zdravilo neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
• Women to have no monthly period or irregular periods. 
• izostanek menstruacij ali neredne menstruacije pri ženskah.
• Do not use Seroquel after the expiry date which is stated on the container after EXP. 
• Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli poleg oznake: »Uporabno do«.
The reduction in total and free T4 was maximal within the first six weeks of quetiapine treatment, with no further reduction during long-term treatment. 
Znižanje celotnega in prostega T4 je bilo največje v prvih šestih tednih zdravljenja s kvetiapinom.
Quetiapine treatment has been associated with somnolence and related symptoms, such as sedation (see Section 4.8). 
Zdravljenje s kvetiapinom je bilo povezano z zaspanostjo in sorodnimi simptomi, npr. sedacijo (glejte poglavje 4.8).
Other than the incidence of extrapyramidal symptoms (see section 4.8 and ‘Clinical Safety' below) the tolerability of Seroquel XR once daily in elderly patients was comparable to that seen in adults (aged 1865 years). 
4.8 in "Klinična varnost", spodaj) so starejši bolniki zdravilo Seroquel SR enkrat na dan prenašali podobno kot odrasli (stari od 18 do 65 let).
If you take more Seroquel XR than you should 
Če ste vzeli večji odmerek zdravila Seroquel SR, kot bi smeli
• Fits or seizures 
• napadi krčev ali konvulzije,
The incidence of relapse was 14.2% for Seroquel XR treated patients and 34.4% for placebo-treated patients. 
Pri bolnikih, ki so dobivali zdravilo Seroquel SR, je bila incidenca recidivov 14,2 %, pri bolnikih, ki so dobivali placebo, pa 34,4 %.
Also caution should be exercised when quetiapine is prescribed either with medicines known to increase QT interval, or with concomitant neuroleptics, especially in the elderly, in patients with congenital long QT syndrome, congestive heart failure, heart hypertrophy, hypokalaemia or hypomagnesaemia (see section 4.5). 
Obenem je potrebna previdnost, če kvetiapin predpišete skupaj z zdravili, za katera je znano, da podaljšajo interval QT ali z drugimi nevroleptiki, posebej pri starejših, pri bolnikih s prirojenim sindromom dolgega intervala QT ter pri bolnikih s kongestivnim srčnim popuščanjem, srčno hipertrofijo, hipokaliemijo ali hipomagneziemijo
(20) Cases of suicidal ideation and suicidal behaviours have been reported during quetiapine therapy or early after treatment discontinuation (see Sections 4.4 and 5.1). 
(20) Med zdravljenjem ali kmalu po prenehanju zdravljenja s kvetiapinom so bili opaženi primeri razmišljanja o samomoru in samomorilno vedenje (glejte poglavji 4.4 in 5.1).
METHOD AND ROUTE(S) OF ADMINISTRATION Do not split, chew or crush the tablets. 
POSTOPEK IN POT(I) UPORABE ZDRAVILA Tablet ne lomite, ne grizite in ne drobite.
Quetiapine data in combination with divalproex or lithium in acute moderate to severe manic episodes is limited; however, combination therapy was well tolerated (see section 4.8 and 5.1). 
Podatki o uporabi kvetiapina v kombinaciji z valproatom ali litijem pri zdravljenju akutnih epizod zmerne do hude manije so omejeni; kombinirano zdravljenje pa so bolniki dobro prenašali (glejte poglavji 4.8 in 5.1).
Venous thromboembolism 
venska trombembolija
If you are, Seroquel XR should not be taken because the group of medicines that Seroquel XR belongs to may increase the risk of stroke, or in some cases the risk of death, in elderly people with dementia. 
Če ste, ne smete jemati zdravila Seroquel SR, kajti skupina zdravil, v katero spada Seroquel SR, lahko starejšim osebam z demenco poveča tveganje možganske kapi in v nekaterih primerih tveganje smrti.
Seroquel contains lactose which is a type of sugar. 
Zdravilo Seroquel vsebuje laktozo, ki je vrsta sladkorja.
When Seroquel XR administered once daily is compared to the same total daily dose of immediate-release quetiapine fumarate (Seroquel immediate release) administered twice daily, the area under the plasma concentration-time curve (AUC) is equivalent, but the maximum plasma concentration (Cmax) is 13% lower at steady state. 
Če primerjamo uporabo zdravila Seroquel SR enkrat na dan z enakim celotnim dnevnim odmerkom kvetiapinijevega fumarata s takojšnjim sproščanjem (zdravilo Seroquel), uporabljenim dvakrat na dan, je površina pod krivuljo koncentracije v plazmi po času (AUC)
Overdose could lead to QT-prolongation, seizures, status epilepticus, rhabdomyolysis, respiratory depression, urinary retention, confusion, delirium and/or agitation, coma and death. 
Preveliko odmerjanje lahko vodi do podaljšanja intervala QT, konvulzij, statusa epilepticusa, rabdomiolize, depresije dihanja,
Seroquel can be administered with or without food. 
Zdravilo Seroquel lahko bolniki jemljejo s hrano ali brez.
Depression in bipolar disorder is associated with an increased risk of suicidal thoughts, self-harm and suicide (suicide-related events). 
Samomor/samomorilne misli ali klinično poslabšanje: Depresija je povezana z večjim tveganjem za pojav samomorilnih misli, samopoškodovanja in samomorilnosti (s samomorom povezani dogodki).
• Increase in the amount of a hormone called prolactin, in the blood. 
• zvišanje koncentracije hormona, imenovanega prolaktin, v krvi.
Do not take Seroquel XR if you are taking any of the following medicines: 
Ne jemljite zdravila Seroquel SR, če jemljete katero od naštetih zdravil:
Seroquel data in combination with divalproex or lithium in acute moderate to severe manic episodes at 3 and 6 weeks is limited; however, combination therapy was well tolerated. 
Podatki o uporabi zdravila Seroquel v kombinaciji z valproatom ali litijem pri zdravljenju akutnih zmernih do hudih maničnih epizod po 3 in 6 tednih so omejeni; kombinirano zdravljenje pa so bolniki dobro prenašali.
The mean quetiapine plasma clearance decreases with approximately 25% in persons with known hepatic impairment (stable alcoholcirrhosis). 
Povprečni plazemski očistek kvetiapina se pri bolnikih z znano okvaro jeter (stabilna alkoholna ciroza) zmanjša za približno 25 %.
Somnolence and dizziness: 
Zaspanost in omotica:
Prolactin levels (patients < 18 years of age): >20 ug/L (>869.56 pmol/L) males; >26 ug/L (>1130.428 pmol/L) females at any time. 
Koncentracija prolaktina (bolniki, stari < 18 let): > 20 µg/l (> 869,56 pmol/l) moški, > 26 µg/l (> 1130,428 pmol/l) ženske kadarkoli.
Based on clinical trial adverse event reports of blood creatine phosphokinase increase not associated with neuroleptic malignant syndrome 15. 
Zvišanje krvnih vrednosti kreatin fosfokinaze, ki ni povezana z malignim nevroleptičnim sindromom.
Longer term relapse prevention trials had an open label period (ranging from 4 to 36 weeks) during which patients were treated with quetiapine, followed by a randomized withdrawal period during which patients were randomized to quetiapine or placebo. 
36 tednov); med odprtim obdobjem so bolniki prejemali kvetiapin, sledilo pa je randomizirano obdobje odtegnitve, med katerim so bolnike randomizirali na kvetiapin ali placebo.
Elevations in serum triglyceride levels 10,30 
Presnovne in prehranske motnje zvišanje koncentracije trigliceridov v serumu 10,30
Cytochrome P450 (CYP) 3A4 is the enzyme that is primarily responsible for the cytochrome P450 mediated metabolism of quetiapine. 
Citokrom P450 (CYP) 3A4 je encim, ki je primarno odgovoren za presnovo kvetiapina s citokromom
(22) Decreased haemoglobin to ≤13 g/dL (8.07 mmol/L) males, ≤12 g/dL (7.45 mmol/L) females on at least one occasion occurred in 11% of quetiapine patients in all trials including open label extensions. 
(21) Glejte poglavje 5.1 (22) Znižanje hemoglobina na ≤ 13 g/dl (8,07 mmol/l) pri moških in ≤ 12 g/dl (7,45 mmol/l) pri ženskah se je vsaj enkrat pojavilo pri 11% bolnikov, ki so prejemali kvetiapin v vseh preskušanjih vključno z odprtimi deli preizkušanj.
(See section 4.4). 
(glejte poglavje 4.4).
Elevations in total cholesterol (predominantly LDL cholesterol) Decreases in HDL cholesterol 17,30, 
Presnovne in prehranske motnje zvišanje koncentracije trigliceridov v serumu zvišanje celotnega holesterola (pretežno holesterola LDL) znižanje holesterola HDL 17,30,
• A combination of high temperature (fever), sweating, stiff muscles, feeling very drowsy or faint (a disorder called “neuroleptic malignant syndrome).” 
• kombinacija zvišane telesne temperature (vročina), znojenja, togih mišic, občutka hude zaspanosti ali omedlevice (to motnjo imenujemo »nevroleptični maligni sindrom«),
Seroquel tablets contain lactose. 
Tablete zdravila Seroquel vsebujejo laktozo.