natgillin/translations-raw huggingface dataset:
If the control window still does not change to red, you may have forgotten to release the orange button before inhaling, or you may not have inhaled strongly enough.
Če se kontrolno okence še vedno ne obarva rdeče, ste morda pred inhaliranjem pozabili sprostiti oranžni gumb, ali pa morda niste dovolj močno inhalirali.
*As the primary endpoint did not achieve statistical significance, all p-values for secondary endpoints are tested at a nominal significance level of 0.05, and no formal statistical inference can be drawn.
*Ker primarni opazovani dogodek ni dosegel statistične značilnosti, so bile vse vrednosti p za sekundarne opazovane dogodke testirane z nominalno ravnjo značilnosti 0,05 in formalno statistično sklepanje ni mogoče.
• Medicines that lower the amount of potassium in your blood.
• zdravila, ki znižujejo raven kalija v krvi.
• Each time you load a dose by pressing the orange button, the dose indicator moves by a small amount towards the next number (50, 40, 30, 20, 10, or 0).
• Vsakič, ko s pritiskom na oranžni gumb naložite odmerek, se indikator odmerka za malenkost premakne proti naslednji številki (50, 40, 30, 20, 10, ali 0).
Some side effects may be serious: if you get any of these side effects, tell your doctor immediately.
Nekateri neželeni učinki so lahko resni: Če pride do katerega od navedenih neželenih učinkov, takoj obvestite zdravnika.
- You can use Brimica Genuair anytime before or after food or drink.
- Zdravilo Brimica Genuair lahko uporabite kadar koli pred uživanjem hrane ali pijače ali po tem.
Hypokalaemia increases susceptibility to cardiac arrhythmias.
Hipokaliemija povečuje dovzetnost za srčne aritmije.
It is important to instruct the patients to read the Instructions for Use in the Package Leaflet.
Pomembno je bolnike poučiti, da natančno preberejo navodila za uporabo v Navodilu za uporabo.
- The recommended dose is one inhalation in the morning and one inhalation in the evening.
- Priporočeni odmerek je en vdih zjutraj in en vdih zvečer.
Orange button
Oranžni gumb
Moreover, post-marketing reports of ‘peripheral oedema' did not show positive re-challenge.
Poleg tega v poročilih po prihodu zdravila na trg pri "perifernih edemih" niso ugotovili pozitivne ponovne provokacije.
If this occurs, medicinal product should be stopped and other treatment will be considered.
Če pride do tega, je treba zdravljenje z zdravilom prekiniti in razmisliti o drugačnem zdravljenju.
The plasma protein binding of formoterol is 61% to 64% (34% primarily to albumin).
Vezava formoterola na plazemske proteine je znašala med 61 % in 64 % (na albumin v osnovi znaša 34 %).
Name and address of the manufacturer responsible for batch release Industrias Farmacéuticas Almirall, S.A.
Ime in naslov izdelovalca, odgovornega za sproščanje serij Industrias Farmacéuticas Almirall, S.A.
• Medicines which can cause a type of change in the electrical activity of the heart known as QT interval prolongation (observed in an electrocardiogram).
• zdravila, ki lahko povzročijo vrsto spremembe električne dejavnosti srca, poznano kot podaljšanje intervala QT (opazi se na elektrokardiogramu).
If a dose is missed, it should be taken as soon as possible and the next dose should be taken at the usual time.
Če se odmerek izpusti, ga je treba uporabiti čim prej, naslednji odmerek pa ob običajnem času.
If you are affected by either of these side effects, do not drive or use machines until the dizziness has cleared or your vision has returned to normal.
Če imate katerega koli od teh neželenih učinkov, ne vozite in ne upravljajte strojev, dokler omotica ne mine in se povrne normalen vid.
Do not hold the orange button down while inhaling.
Ne držite oranžnega gumba navzdol, medtem ko inhalirate.
If you use Brimica Genuair with some other medicines, the effect of Brimica Genuair or the other medicines may be altered.
Če zdravilo Brimica Genuair uporabljate z drugimi zdravili, se lahko učinek zdravila Brimica Genuair ali drugih zdravil spremeni.
Each delivered dose contains approximately 11 mg lactose (as monohydrate).
En dostavljen odmerek vsebuje približno 11 mg laktoze (v obliki monohidrata).
The frequency of adverse reactions is defined using the following convention: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000) and not known (cannot be estimated from available data).
Pogostnost neželenih učinkov je opredeljena po naslednjem dogovoru: zelo pogosti (≥1/10), pogosti (≥1/100 do <1/10), občasni (≥1/1.000 do <1/100), redki (≥1/10.000 do <1/1.000), zelo redki (<1/10.000) in neznana (ni mogoče oceniti iz razpoložljivih podatkov).
The most frequently reported adverse reactions with Brimica Genuair were nasopharyngitis (7.9%) and headache (6.8%).
Najpogosteje poročana neželena učinka zdravila Brimica Genuair sta bila nazofaringitis (7,9 %) in glavobol (6,8 %).
Brimica Genuair should only be used during pregnancy if the expected benefits outweigh the potential risks.
Zdravilo Brimica Genuair se lahko uporablja med nosečnostjo samo, če se pričakuje, da koristi odtehtajo morebitna tveganja.
Even though the orange button is locked, your last dose may still be inhaled.
Tudi če je oranžni gumb zaklenjen, lahko še vedno vdihnete zadnji odmerek.
The combination of these substances with different mechanisms of action results in additive efficacy compared to that achieved with either component alone.
Kombinacija teh učinkovin z različnima mehanizmoma delovanja je dodatno prispevala k učinkovitosti v primerjavi z učinkovitostjo posamezne učinkovine.
It is unknown whether aclidinium (and/or its metabolites) or formoterol are excreted in human milk.
Ni znano, ali se aklidinij (in/ali njegovi presnovki) ali formoterol izločata v materino mleko.
Cytochrome P450 isoenzymes CYP2D6, CYP2C19, CYP2C9 and CYP2A6 are involved in the O-demethylation of formoterol.
Izoencimi citokroma P450 (CYP2D6, CYP2C19, CYP2C9 in CYP2A6) so vpleteni v proces O-demetilacije formoterola.
These effects are known exaggerated pharmacological responses observed with β2-agonists.
Ti učinki so znani pretirani farmakološki odzivi, opaženi pri agonistih β2.
Aclidinium is rapidly and extensively hydrolysed to its pharmacologically inactive alcohol- and carboxylic acid-derivatives.
Aklidinij se hitro in obširno hidrolizira v farmakološko neaktivne derivate alkohola in karboksilne kisline.
Aclidinium/formoterol did not statistically significantly reduce the average number of night-time awakenings due to COPD compared with placebo or formoterol.
Aklidinij/formoterol ni statistično pomembno zmanjšal povprečnega števila zbujanj ponoči zaradi KOPB v primerjavi s placebom ali formoterolom.
It is important that you read this information as the Genuair may work differently from inhalers you have used previously.
Pomembno je, da preberete te informacije, ker lahko inhalator Genuair deluje drugače od inhalatorjev, ki ste jih že prej uporabljali.
Hypokalaemic treatment
Hipokaliemično zdravljenje
Keep breathing in for as long as possible.
Nadaljujte z vdihavanjem kolikor dolgo je mogoče.
Make sure you have released the orange button, and you have breathed out completely.
Preverite, da ste sprostili oranžni gumb in da ste v celoti izdihnili.
Since aclidinium bromide is quickly broken down in plasma, the level of systemic anticholinergic undesirable effects is low.
Aklidinijev bromid se hitro razgrajuje v plazmi, zato je raven sistemskih antiholinergičnih neželenih učinkov nizka.
No dose adjustments are necessary in these patients.
Prilagajanje odmerka pri teh bolnikih ni potrebno.
Squeeze here and pull
Tukaj stisnite in povlecite
Do not use Brimica Genuair: - if you are allergic to aclidinium, formoterol fumarate dihydrate or to the other ingredient of this medicine (listed in Section 6).
Ne uporabljajte zdravila Brimica Genuair: - če ste alergični na aklidinij, formoterolijev fumarat dihidrat ali katero koli drugo sestavino tega zdravila (navedeno v poglavju 6).
Pharmacotherapeutic group: Drugs for obstructive airway diseases, adrenergics in combination with anticholinergics, ATC code: R03AL05
Farmakoterapevtska skupina: zdravila za obstruktivne pljučne bolezni, adrenergiki v kombinaciji z antiholinergiki, oznaka ATC: R03AL05
Stop and Check:
Preden nadaljujete, preverite:
The low absolute bioavailability of inhaled aclidinium (<5%) is because aclidinium undergoes extensive systemic and pre-systemic hydrolysis whether deposited in the lung or swallowed.
Nizka absolutna biološka razpoložljivost inhaliranega aklidinija (< 5 %) je posledica obširne sistemske in predsistemske hidrolize aklidinija, odloženega v pljuča ali zaužitega.
The European Medicines Agency has waived the obligation to submit the results of studies with Brimica Genuair in all subsets of the paediatric population in COPD (see section 4.2 for information on paediatric use).
Evropska agencija za zdravila je odstopila od zahteve za predložitev rezultatov študij z zdravilom Brimica Genuair za vse podskupine pediatrične populacije s KOPB (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
The presentation of the safety profile is based on the experience with Brimica Genuair and the individual components.
Prikaz varnostnega profila temelji na izkušnjah z zdravilom Brimica Genuair in njegovima posameznima učinkovinama.
*Half-life consistent with product accumulation based on a known dose regimen.
*Razpolovni čas, ki se ujema s kopičenjem zdravila na podlagi znane odmerne sheme.
Preferred term
Izbrani izraz
You should not use Brimica Genuair if you are pregnant or are breast-feeding unless your doctor tells you to do so.
Zdravila Brimica Genuair ne smete uporabljati, če ste noseči ali dojite, razen če vam tako ne naroči zdravnik.
In some patients, this medicine may cause blurred vision or dizziness.
To zdravilo lahko pri nekaterih bolnikih povzroči zamegljen vid ali omotico.
Other side effects which may occur while using Brimica Genuair:
Drugi neželeni učinki, ki se lahko pojavijo med uporabo zdravila Brimica Genuair:
Do not use Brimica Genuair if you notice that the pack is damaged or shows signs of tampering.
Ne uporabljajte zdravila Brimica Genuair, če opazite, da je ovojnina poškodovana ali kaže znake poseganja vanjo.
Stop using the medicine and contact your doctor immediately if you:
Prenehajte uporabljati zdravilo in se nemudoma posvetujte z zdravnikom:
Do not use this medicine after the expiry date which is stated on the inhaler label, carton and inhaler bag after “EXP”.
Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na nalepki inhalatorja, škatli in vrečki inhalatorja poleg oznake »EXP«.
Submission of the results of the agreed post-authorisation safety study (PASS) for aclidinium bromide to evaluate the overall mortality and the proposed cardiovascular safety endpoints (with an additional endpoint of cardiac arrhythmia) among patients with COPD using aclidinium/formoterol, according to a protocol agreed by the PRAC.
Predložitev rezultatov dogovorjene študije varnosti po izdaji dovoljenja za promet z zdravilom (post-authorisation safety study, PASS) za aklidinijev bromid za ocenjevanje skupne umrljivosti in predlaganih kardiovaskularnih varnostnih končnih točk (z dodatno končno točko srčne aritmije) pri bolnikih s KOPB, ki uporabljajo aklidinij/formoterol, skladno s protokolom, o katerem se je dogovoril odbor PRAC.
- Instructions for use: Refer to the Instructions for Use at the end of this leaflet for instructions on how to use the Genuair inhaler.
- Navodila za uporabo: Za navodila o uporabi inhalatorja Genuair glejte navodila za uporabo zdravila na koncu teh Navodil za uporabo.
COPD is a long-term disease; therefore, Brimica Genuair is for long-term use.
KOPB je dolgotrajna bolezen, zato je tudi zdravilo Brimica Genuair namenjeno za dolgotrajno uporabo.
If your usual COPD symptoms (breathlessness, wheezing, cough) do not improve or get worse while you are using Brimica Genuair you should continue to use it, but go to see your doctor as soon as possible because you may need another medicine.
Če se vaši simptomi KOPB (zadihanost, piskajoče dihanje ali kašelj) med uporabo zdravila Brimica Genuair ne izboljšajo ali če se poslabšajo, nadaljujte z uporabo zdravila, vendar čim prej obiščite zdravnika, saj boste morda potrebovali drugo zdravilo.
Children and adolescents Brimica Genuair is not for use in children or adolescents below 18 years of age.
Otroci in mladostniki Zdravilo Brimica Genuair ni namenjeno za otroke ali mladostnike do 18. leta starosti.
Medicinal products that are known to prolong the QTc interval are associated with an increased risk of ventricular arrhythmias.
Zdravila, ki dokazano podaljšujejo interval QTc, so povezana s povečanim tveganjem za prekatne aritmije.
ALUMINIUM BAG
ALUMINIJASTA VREČKA
However, paradoxical bronchospasm has been observed with other inhalation therapies.
Paradoksni bronhospazem pa so opazili pri drugih vrstah inhalacijskih terapij.
Taking Brimica Genuair regularly will reduce the effects of COPD on your everyday life.
Redna uporaba zdravila Brimica Genuair zmanjša učinke bolezni KOPB na vaše vsakdanje življenje.
Go back to ‘STEP 1 Prepare your dose' and repeat steps 1.1 to 1.6.
Vrnite se na ‘KORAK 1 Priprava odmerka' in ponovite korake 1.1 do
1.5 Release the orange button (Figure F).
1.5 Sprostite oranžni gumb (Slika F).
Brimica Genuair should be discontinued in case of overdose.
Zdravljenje z zdravilom Brimica Genuair je treba v primeru prevelikega odmerjanja prekiniti.
These may be signs of a condition called “paradoxical bronchospasm”, which is an excessive and prolonged contraction of the airway muscles immediately following treatment with a bronchodilator.
To so lahko znaki stanja, imenovanega »paradoksni bronhospazem«: prekomernega in dolgotrajnega skrčenja mišic v dihalnih poteh takoj po uporabi bronhodilatatorja.
- The other ingredient is lactose monohydrate (see end of section 2 under ‘Brimica Genuair contains lactose' for more information).
- Druga sestavina zdravila je laktoza monohidrat (za več informacij glejte konec poglavja 2 pod naslovom »Zdravilo Brimica Genuair vsebuje laktozo«).
c. Pull off the cap by lightly squeezing the arrows marked on each side (Figure B).
c) Odstranite pokrovček, tako da rahlo stisnete puščici, označeni na vsaki strani (Slika B).
The safety experience with Brimica Genuair comprised exposure in clinical trials at the recommended therapeutic dose for up to 12 months, and in post-marketing experience.
Izkušnje o varnosti z zdravilom Brimica Genuair vključujejo izpostavljenost v kliničnih preskušanjih do 12 mesecev pri priporočenem terapevtskem odmerku in izkušnje iz obdobja trženja zdravila.
b. Do not press the orange button until you are ready to take a dose.
b) Ne pritisnite oranžnega gumba, dokler niste pripravljeni, da vzamete odmerek.
The main plasma protein that binds aclidinium is albumin.
Glavni plazemski protein, ki veže aklidinijev bromid, je albumin.
Mean effective half-lives* observed for both aclidinium and formoterol (based on the accumulation ratio) are approximately 10 hours.
Povprečni efektivni razpolovni čas* tako aklidinija kot formoterola (na podlagi razmerja kopičenja) je bil približno 10 ur.
Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucosegalactose malabsorption should not take this medicinal product.
Bolniki z redko dedno intoleranco na galaktozo, odsotnostjo encima laktaze ali malabsorpcijo glukoze/galaktoze, ne smejo jemati tega zdravila.
After inhalation, 6% to 9% of the delivered dose of formoterol is excreted in the urine unchanged or as direct conjugates of formoterol.
Po inhalaciji se od 6 % do 9 % dostavljenega odmerka formoterola izloči v urinu v nespremenjeni obliki ali v obliki njegovega konjugata.
[arrow] Tear here
[puščica] Odprite tukaj.
No clinically significant effects of Brimica Genuair on cardiac rhythm were observed on 24-hour Holter monitoring in a subset of 551 patients, of whom 114 received Brimica Genuair twice daily.
Poleg tega niso opazili nobenih klinično pomembnih učinkov zdravila Brimica Genuair na srčni ritem v 24-urnem spremljanju z napravo Holter v podskupini 551 bolnikov, od katerih jih je 114 prejemalo zdravilo Brimica Genuair dvakrat na dan.
• When a red band appears in the dose indicator, this means you are nearing your last dose(Figure
• Ko se na indikatorju odmerka pojavi rdeča oznaka, to pomeni, da se približujete zadnjemu odmerku (Slika N), ali
1.3 Hold the inhaler horizontally with the mouthpiece facing you and the orange button on top (Figure D).
1.3 Držite inhalator vodoravno, z ustnikom obrnjenim proti vam in z oranžnim gumbom na vrhu (Slika D).
The plasma protein binding of aclidinium determined in vitro most likely corresponded to the protein binding of the metabolites due to the rapid hydrolysis of aclidinium in plasma; plasma protein binding was 87% for the carboxylic acid metabolite and 15% for the alcohol metabolite.
Vezava aklidinija na plazemske proteine, ki je bila ugotovljena in vitro, je najverjetneje ustrezala vezavi presnovkov na proteine zaradi hitre hidrolize aklidinija v plazmi; vezanje na plazemske proteine je znašalo 87 % za karboksikislinski presnovek in 15 % za alkoholni presnovek.
Dry mouth, which has been observed with anticholinergic treatment, may in the long term be associated with dental caries.
Suha usta, učinek, ki ga opažajo pri zdravljenju z antiholinergiki, so lahko dolgoročno povezana z zobno gnilobo.
There are no data available on the use of Brimica Genuair in pregnant women.
Podatkov o uporabi zdravila Brimica Genuair pri nosečnicah ni.
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor, nurse or pharmacist for advice before using this medicine.
Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom, medicinsko sestro ali farmacevtom, preden uporabite to zdravilo.
Brimica Genuair should not be used in asthma; clinical studies of Brimica Genuair in asthma have not been conducted.
Zdravilo Brimica Genuair ni namenjeno uporabi pri astmi; klinične študije z zdravilom Brimica Genuair pri astmi niso bile izvedene.
The mouthpiece is covered with a removable orange protective cap.
Ustnik je prekrit z odstranljivim oranžnim zaščitnim pokrovčkom.
Concomitant treatment with methylxanthine derivatives, steroids, or non-potassium-sparing diuretics may potentiate the possible hypokalaemic effect of β2-adrenergic agonists, therefore caution is advised in their concomitant use (see section 4.4).
Sočasno hipokaliemično zdravljenje z metilksantinskimi derivati, steroidi ali diuretiki, ki ne varčujejo s kalijem, lahko stopnjuje možni hipokaliemični učinek agonistov β2-adrenergičnih receptorjev, zato je pri sočasni uporabi potrebna previdnost (glejte poglavje 4.4).
In the long-term, dry mouth can be associated with tooth decay, so it is important to pay attention to oral hygiene.
Suha usta so lahko na dolgi rok povezana z zobno gnilobo, zaradi česar morate biti pozorni na ustno higieno.
• On first use, every inhaler contains at least 60 doses, or at least 30 doses, depending on the pack size.
• Ob prvi uporabi, vsak inhalator vsebuje najmanj 60 odmerkov ali najmanj 30 odmerkov,
Formoterol is a potent selective β2-adrenoceptor agonist.
Formoterol je močan selektivni agonist β2-adrenergičnih receptorjev.
During these studies, patients were permitted to continue their stable treatment with inhaled corticosteroids, low doses of oral corticosteroids, oxygen therapy (if less than 15h/day) or methylxanthines and to use salbutamol as rescue medication.
Med trajanjem teh študij so lahko bolniki nadaljevali stalno zdravljenje s kortikosteroidi za vdihavanje, nizkimi odmerki peroralnih kortikosteroidov, zdravljenjem s kisikom (če je krajše od 15 ur/dan) ali metilksantini in uporabo salbutamola kot reševalnega zdravila.
Efficacy was assessed by measures of lung function, symptomatic outcomes, disease-specific health status, rescue medication use, and exacerbations.
Učinkovitost so ocenjevali z merjenjem pljučne funkcije, simptomatskimi izidi, od bolezni odvisnim zdravstvenim stanjem, uporabo reševalnega zdravila in pojavom poslabšanj.
In addition to improving pulmonary function, formoterol has been shown to improve symptoms and quality of life in patients with COPD.
Formoterol poleg izboljšanja pljučne funkcije dokazano izboljšuje simptome in kakovost življenja bolnikov s KOPB.
COPD exacerbation reductions
Zmanjšanje poslabšanja KOPB
The Genuair inhaler is a multicomponent device made of plastic (polycarbonate, acrylonitrilebutadiene-styrene, polyoxymethylene, polyester-butylene-terephthalate, polypropylene, polystyrene) and stainless steel.
Inhalator Genuair sestavlja več kosov, izdelanih iz plastike (polikarbonata, akrilonitril-butadien-stirena, polioksimetilena, poliester-butilen-tereftalata, polipropilena, polistirena) in nerjavnega jekla.
Lung volumes, exercise endurance and physical activity The effect of Brimica Genuair on lung volumes, exercise endurance and physical activity was investigated in an 8-week parallel, randomised, placebo-controlled clinical study in COPD patients with hyperinflation (functional residual capacity [FRC] >120%).
Pljučni volumni, obremenitvena vzdržljivost in telesna dejavnost Vpliv zdravila Brimica Genuair na pljučne volumne, obremenitveno vzdržljivost in telesno dejavnost so raziskali v 8-tedenski vzporedni, randomizirani, s placebom kontrolirani klinični študiji bolnikov s KOPB, ki so imeli hiperinflacijo (funkcionalna rezidualna kapaciteta [FRC] > 120 %).
In Phase III clinical studies, the frequency of notable increases in blood glucose with Brimica Genuair was low (0.1%) and similar to placebo.
V kliničnih študijah 3. faze zdravila Brimica Genuair je bila pogostnost pomembnega povečanja glukoze v krvi nizka (0,1 %) in podobna ravni s placebom.
The occurrence of blurred vision or dizziness may influence the ability to drive or to use machines.
Pojav zamegljenega vida ali omotice lahko vpliva na sposobnost vožnje ali upravljanja s stroji.
Hypersensitivity to the active substances or to the excipient listed in section 6.1.
Preobčutljivost na učinkovini ali katero koli pomožno snov, navedeno v poglavju 6.1.
There are no data regarding the specific use of aclidinium/formoterol in patients with renal or hepatic impairment.
Na voljo ni nobenih podatkov o specifični uporabi aklidinija/formoterola pri bolnikih z ledvično ali jetrno okvaro.
Other medicines and Brimica Genuair
Druga zdravila in zdravilo Brimica Genuair
The onset of action of Brimica Genuair was comparable to the effect of the fast-acting β2-agonist formoterol 12 micrograms.
Začetek delovanja zdravila Brimica Genuair je primerljiv z učinkom hitro delujočega agonista β2 formoterola 12 mikrogramov.
Bronchodilators relax the muscles in your airways, which allows the airways to open more widely and helps you to breathe more easily.
Bronhodilatatorji sproščajo mišice v dihalnih poteh, kar omogoča širše odprtje dihalnih poti in s tem pripomorejo k lažjemu dihanju.
Biotransformation via CYP450 enzymes plays a minor role in the total metabolic clearance of aclidinium.
Biološka transformacija prek encimov CYP450 igra manjšo vlogo pri skupnem presnovnem očistku aklidinija.
Based on the above mentioned data, the PRAC considered that ‘peripheral oedema' should be removed from the list of adverse drug reactions in section 4.8 of the SmPC and ‘Swelling of hands, ankles or feet' should be deleted in section 4 of the Package Leaflet.
Na podlagi zgoraj omenjenih podatkov odbor PRAC meni, da je treba "periferne edeme" odstraniti s seznama neželenih učinkov zdravila v poglavju 4.8 Povzetka glavnih značilnosti zdravila in "Otekanje dlani, gležnjev ali stopal" izbrisati iz poglavja 4 Navodila za uporabo.
In case such effects occur, treatment may need to be discontinued.
Če se pojavijo ti učinki, je treba razmisliti o prekinitvi zdravljenja.
The Brimica Genuair clinical development programme was conducted in patients with moderate or severe COPD.
Klinični razvojni program zdravila Brimica Genuair je bil izveden pri bolnikih z zmerno ali hudo KOPB.