natgillin/translations-raw huggingface dataset:
• Infectious Sinusitis and Airsacculitis caused by M. gallisepticum, M. synoviae and M. meleagridis: 40 mg tiamulin hydrogen fumarate (equivalent to 88.9 mg of product)/kg body weight administered daily for the period of 3 to 5 consecutive days
• Infekcijski sinusitis in vnetje zračnih vrečk, ki ju povzročajo M. gallisepticum, M. synoviae in M. meleagridis: Dnevni odmerek 40 mg tiamulinijevega hidrogenfumarata (kar ustreza 88,9 mg zdravila)/kg telesne mase v obdobju 3 do 5 dni zaporedoma.
In these studies the MICs ranged from ≤0.008-64 µg/ml, with MIC50s of ≤0.062 µg/ml up to 0.125 µg/ml and MIC90s of 0.25 µg/ml up to 8 µg/ml.
V teh študijah so bile MIK v razponu med ≤ 0,008 in 64 µg/ml, MIK50 v razponu med ≤ 0,062 µg/ml in 0,125 µg/ml ter MIK90 v razponu med 0,25 µg/ml in 8 µg/ml.
• Chronic Respiratory Disease caused by M. gallisepticum and Airsacculitis and Infectious Synovitis caused by M. synoviae: 25 mg tiamulin hydrogen fumarate (equivalent to 55.6 mg of product)/kg body weight administered daily for the period of 3 to 5 consecutive days.
• Kronična respiratorna bolezen, ki jo povzroča M. gallisepticum, ter vnetje zračnih vrečk in infekcijski sinovitis, ki ju povzroča M. synoviae: Dnevni odmerek 25 mg tiamulinijevega hidrogenfumarata (kar ustreza 55,6 mg zdravila)/kg telesne mase v obdobju 3 do 5 dni zaporedoma.
Turkeys Meat and offal: 6 days
Purani Meso in organi: 6 dni.
iii) For the treatment of Porcine Proliferative Enteropathy (ileitis) caused by Lawsonia intracellularis.
iii) Za zdravljenje proliferativne enteropatije (ileitisa) pri prašičih, ki jo povzroča Lawsonia intracellularis.
Tiamulin has been shown to interact with ionophores such as monensin, salinomycin and narasin and may result in signs indistinguishable from an ionophore toxicosis.
4.8 Medsebojno delovanje z drugimi zdravili in druge oblike interakcij Tiamulin dokazano medsebojno deluje z ionoforji, kot so monenzin, salinomicin in narazin, kar lahko povzroči znake, ki jih ni mogoče ločiti od zastrupitve z ionoforji.
Water intake may be depressed during the administration of tiamulin in birds.
Vnos vode se pri pticah med zdravljenjem s tiamulinom lahko zmanjša.
• Enzootic Pneumonia caused by M hyopneumoniae, including infections complicated by Pasteurella multocida, or Pleuropneumonia caused by A. pleuropneumoniae: 20 mg tiamulin hydrogen fumarate (equivalent to 44.4 mg of product)/kg body weight administered daily for 5 consecutive days.
• Enzootska pljučnica, ki jo povzroča M. hyopneumoniae, vključno z okužbami, ki se zapletejo zaradi bakterije Pasteurella multocida, in plevropneumonija, ki jo povzroča A. pleuropneumoniae: Dnevni odmerek 20 mg tiamulinijevega hidrogenfumarata (kar ustreza 44,4 mg zdravila)/kg telesne mase v pitni vodi za prašiče v obdobju 5 dni zaporedoma.
Denagard 45% is a veterinary medicinal product presented as granules for use in drinking water for pigs, chicken and turkeys containing 450 mg tiamulin hydrogen fumarate per gram product.
Zdravilo Denagard 45% je zdravilo za uporabo v veterinarski medicini, na voljo v obliki zrnc za uporabo v pitni vodi za prašiče, piščance in purane, ki vsebuje 450 mg tiamulinijevega hidrogenfumarata na gram zdravila.
Denagard 45% and its associated names are veterinary medicinal products presented as granules for use in drinking water for pigs, chicken and turkeys containing 450 mg tiamulin hydrogen fumarate as an active substance per gram product.
Zdravilo Denagard 45% in povezana imena so zdravila za uporabo v veterinarski medicini, na voljo v obliki zrnc za uporabo v pitni vodi za prašiče, piščance in purane, ki kot zdravilno učinkovino vsebujejo 450 mg tiamulinijevega hidrogenfumarata na gram zdravila.
In the field trials tiamulin was administered at inclusion rates of 125 - 250 ppm or daily doses from 12.7 to 59.7 mg tiamulin hydrogen fumarate/kg body weight for three days.
V terenskih preskušanjih je bila uporabljena vsebnost tiamulina 125-250 ppm oziroma dnevni odmerki 12,7-59,7 mg tiamulinijevega hidrogenfumarata/kg telesne mase v obdobju treh dni.
In drinking water
dajanje v vodo za pitje
Pregnancy and lactation: Can be used in pigs during pregnancy and lactation.
Lahko se uporablja pri prašičih v obdobju brejosti in laktacije.
In turkeys serum levels of tiamulin hydrogen fumarate are lower with a 50 mg tiamulin hydrogen fumarate/kg body weight single dose giving a Cmax of 3.02 µg/ml in serum, and 25 mg/kg giving 1.46 µg/ml.
Pri puranih so serumske koncentracije tiamulinijevega hidrogenfumarata po enkratnem odmerku 50 mg tiamulinijevega hidrogenfumarata/kg telesne mase manjše, in sicer je vrednost Cmax 3,02 µg/ml, po odmerku 25 mg/kg pa 1,46 µg/ml.
From these data the CVMP concluded that Denagard 45% at a dose of 40 mg tiamulin hydrogen fumarate (equivalent to 88.9 mg of product)/kg body weight for three to five consecutive days would be efficacious in the treatment and metaphylaxis of Infectious Sinusitis and Airsacculitis caused by Mycoplasma gallisepticum, Mycoplasma synoviae and Mycoplasma meleagridis susceptible to tiamulin.
Na podlagi teh podatkov je odbor CVMP zaključil, da je zdravilo Denagard 45 % v odmerku 40 mg tiamulinijevega hidrogenfumarata (kar ustreza 88,9 mg zdravila)/kg telesne mase v obdobju treh do petih dni zaporedoma učinkovito pri zdravljenju in metafilaksi infeksijckskega sinusitisa in vnetja zračnih vrečk, ki ju povzročajo Mycoplasma gallisepticum, Mycoplasma synoviae in Mycoplasma meleagridis, občutljive za tiamulin.
For M. synoviae MICs ranged from 0.05 to 0.5 µg/ml with MIC50s of 0.1 µg/ml and a MIC90 of 0.25 µg/ml.
MIK za M. synoviae so bile v razponu med 0,05 in 0,5 µg/ml z MIK50 0,1 µg/ml in MIK90 0,25 µg/ml.
The artificial infection studies were carried out using tiamulin inclusion rates in drinking water ranging from 60 to 250 ppm or estimated daily doses from 15.4 to 64.2 mg tiamulin hydrogen fumarate/kg body weight.
Študiji z umetno okužbo sta bili opravljeni z uporabo vsebnosti tiamulina v pitni vodi med 60 in 250 ppm oziroma z ocenjenimi dnevnimi odmerki od 15,4 do 64,2 mg tiamulinijevega hidrogenfumarata/kg telesne mase.
The indication treatment of Porcine Proliferative Enteropathy (ileitis) caused by L. intracellularis was supported by in vitro susceptibility data, artificial infection studies and a field trial.
Indikacijo zdravljenja prašičje proliferativne enteropatije (ileitisa), ki jo povzroča L. intracellularis, podpirajo podatki o občutljivosti in vitro, študije z umetno okužbo in terensko preskušanje.
Guidance for preparing product solutions:
Navodila za pripravo raztopine zdravila:
Following a single oral dose of 10 mg and 25 mg tiamulin hydrogen fumarate/kg body weight the Cmax was 1.03 µg/ml and 1.82 µg/ml in serum respectively by microbiological assay and the Tmax was 2 hours for both.
Po enkratnem peroralnem odmerku 10 mg in 25 mg tiamulinijevega hidrogenfumarata/kg telesne mase sta bili vrednosti Cmax, določeni z mikrobiološkim testom, 1,03 µg/ml oziroma 1,82 µg/ml, čas tmax pa je bil v obeh primerih 2 uri.
ii) For the treatment of Porcine Colonic Spirochaetosis (colitis) caused by Brachyspira pilosicoli.
ii) Za zdravljenje spirohetoze debelega črevesa (kolitisa) pri prašičih, ki jo povzroča Brachyspira pilosicoli.
Consequently, a withdrawal period in eggs of zero days is accepted.
Zato je sprejeta karenca za jajca nič dni.
Tiamulin at inclusion rates of 100 ppm (equivalent to 5 mg tiamulin hydrogen fumarate/kg body weight) and doses of 8 mg tiamulin hydrogen fumarate/kg body weight was administered for five to ten days.
Tiamulin so dajali pet do deset dni z vsebnostjo 100 ppm (kar ustreza 5 mg tiamulinijevega hidrogenfumarata/kg telesne mase) in odmerkom 8 mg tiamulinijevega hidrogenfumarata/kg telesne mase.
iMIC50 was 0.125 µg/ml, iMIC90 0.125 µg/ml with an iMIC range of 0.125-0.5 µg/ml.
iMIK50 je bila 0,125 µg/ml, iMIK90 0,125 µg/ml z razponom iMIK med 0,125 in 0,5 µg/ml.
• Swine Dysentery caused by B hyodysenteriae or Porcine Colonic Spirochaetosis (colitis) caused by B.pilosicoli: 8.8 mg tiamulin hydrogen fumarate (equivalent to 19.6 mg of product)/kg body weight administered daily in the drinking water of pigs for 3 to 5 consecutive days depending on the severity of the infection and/or the duration of the disease.
• Prašičja dizenterija, ki jo povzroča B. hyodysenteriae,in spirohetoza debelega črevesa (ileitis) pri prašičih, ki jo povzroča B. pilosicoli: Dnevni odmerek 8,8 mg tiamulinijevega hidrogenfumarata (kar ustreza 19,6 mg zdravila)/kg telesne mase v pitni vodi za prašiče v obdobju 3 do 5 dni zaporedoma, odvisno od resnosti okužbe in/ali trajanja bolezni.
450 mg/g Oral granules Swine, chickens (broilers, rearing of broilers, layers / breeders), turkeys (for fattening and breeding)
450 mg/g peroralna zrnca prašiči, piščanci (brojlerji, brojlerji za rejo, nesnice/vzrejne živali), purani (ta pitanje in vzrejo)
Animals should not receive products containing monensin, salinomycin or narasin during or at least 7 days before or after treatment with tiamulin.
Živali med zdravljenjem s tiamulinom ali vsaj 7 dni pred njim oziroma 7 dni po njem ne smejo prejemati zdravil, ki vsebujejo monenzin, salinomicin ali narazin.
EXP {month/year}
Datum izteka roka uporabnosti zdravila EXP: {mesec/leto}
The Netherlands Elanco Europe Ltd. Lilly House, Priestley Road Basingstoke, Hampshire RG24 9NL
Nizozemska Elanco Europe Ltd. Lilly House, Priestley Road Basingstoke, Hampshire RG24 9NL
Lactose
Karenca
Following a 50 mg tiamulin hydrogen fumarate/kg body weight single dose the Cmax was 4.02 µg/ml in serum by microbiological assay and after a 25 mg/kg dose it was 1.86 µg/ml.
Po enkratnem odmerku 50 mg tiamulinijevega hidrogenfumarata/kg telesne mase je bila vrednost Cmax v serumu, določena z mikrobiološkim testom, 4,02 µg/ml, po odmerku 25 mg/kg pa 1,86 µg/ml.
Denagard 45% granulat dla świń, kur i indyków
Denagard 45% granulat dla świń, kur i indyków tiamulinijev hidrogenfumarat
DENAGARD 45%, κοκκία για πόσιμο διάλυμα
DENAGARD 45%, κοκκία για πόσιμο διάλυμα tiamulinijev hidrogenfumarat
The presence of the disease in the flock must be established before the product is used.
Pred uporabo zdravila je treba ugotoviti prisotnost bolezni v jati.
• Treatment and metaphylaxis of Infectious Sinusitis and Airsacculitis caused by M. gallisepticum, M. synoviae and M. meleagridis susceptible to tiamulin.
• Zdravljenje in metafilaksa infekcijskega sinusitisa in vnetja zračnih vrečk, ki ju povzročajo M. gallisepticum, M. synoviae in M. meleagridis, občutljive za tiamulin.
Groups of birds were sacrified at 0 hours, 8 hours, 1 day, 2 days, 3 days and 5 days after withdrawal of treatment and samples from muscle (mixed samples from breast and leg), liver, skin and underlying subcutaneous fat were taken for residue analysis.
Skupine ptic so žrtvovali po 0 urah, 8 urah, 1 dnevu, 2 dneh, 3 dneh in 5 dneh po ukinitvi zdravljenja.
• Treatment of Swine Dysentery caused by B. hyodysenteriae susceptible to tiamulin.
• Zdravljenje prašičje dizenterije, ki jo povzroča B. hyodysenteriae, občutljiva za tiamulin.
For M. synoviae MICs ranged from 0.004 to 0.5 µg/ml with a MIC50 of 0,125 µg/ml and a MIC90 of 0.25 µg/ml.
MIK za M. synoviae so bile v razponu med 0,004 in 0,5 µg/ml z MIK50 0,125 µg/ml in MIK90 0,25 µg/ml.
In chicken a GLP-compliant residue depletion study in laying hens was conducted.
Pri kokoših nesnicah so opravili študijo izločanja ostankov, skladno z dobro laboratorijsko prakso.
Slovak Republic Elanco Europe Ltd. Lilly House, Priestley Road Basingstoke, Hampshire RG24 9NL
Portugalska Elanco Europe Ltd. Lilly House, Priestley Road Basingstoke, Hampshire RG24 9NL
• Treatment of Porcine Proliferative Enteropathy (ileitis) caused by L. intracellularis susceptible to tiamulin.
• Zdravljenje prašičje proliferativne enteropatije (ileitisa), ki jo povzroča L. intracellularis, občutljiva za tiamulin.
Artificial challenge studies were carried out using tiamulin inclusion rates in drinking water ranging from 60 to 250 ppm or estimated doses from 10 to 64.2 mg tiamulin hydrogen fumarate/kg body weight.
Opravljene so bile študije z umetno izpostavitvijo, v katerih je bila uporabljena vsebnost tiamulina v pitni vodi med 60 in 250 ppm oziroma ocenjeni odmerki od 10 do 64,2 mg tiamulinijevega hidrogenfumarata/kg telesne mase.
From these data the CVMP concluded that Denagard 45% at a dose of 25 mg tiamulin hydrogen fumarate (equivalent to 55.6 mg of product)/kg body weight for three to five consecutive days would be efficacious in the treatment and metaphylaxis of Chronic Respiratory Disease caused by M. gallisepticum.
Na podlagi teh podatkov je odbor CVMP zaključil, da je zdravilo Denagard 45% v odmerku 25 mg tiamulinijevega hidrogenfumarata (kar ustreza 55,6 mg zdravila)/kg telesne mase v obdobju treh do petih dni zaporedoma učinkovito pri zdravljenju in metafilaksi kronične respiratorne bolezni, ki jo povzroča M. gallisepticum.
Target species chickens, indications and posology
Ciljna vrsta piščanci, indikacije in način odmerjanja
From these data the CVMP concluded that Denagard 45% at a dose of 20 mg tiamulin hydrogen fumarate (equivalent to 44.4 mg of product)/kg body weight for five consecutive days would be efficacious in the treatment and metaphylaxis of Enzootic Pneumonia caused by M. hyopneumoniae, including infections complicated by P. multocida.
Na podlagi teh podatkov je odbor CVMP zaključil, da je zdravilo Denagard 45% v odmerku 20 mg tiamulinijevega hidrogenfumarata (kar ustreza 44,4 mg zdravila)/kg telesne mase v obdobju petih dni zaporedoma učinkovito pri zdravljenju in metafilaksi enzootske pljučnice, ki jo povzroča M. hyopneumoniae, vključno z okužbami, ki se zapletejo zaradi P. multocida.
Denagard 450 mg/g Granulat zum Eingeben über das Trinkwasser
Denagard 450 mg/g Granulat zum Eingeben über das Trinkwasser tiamulinijev hidrogenfumarat
Denagard vet 450 mg/g rakeet
Denagard vet 450 mg/g rakeet tiamulinijev hidrogenfumarat
DENAGARD 450 mg/g granule pro přípravu perorálního roztoku
DENAGARD 450 mg/g granule pro přípravu perorálního roztoku tiamulinijev hidrogenfumarat
• Treatment of Pleuropneumonia caused by A. pleuropneumoniae susceptible to tiamulin.
• Zdravljenje plevropnevmonije, ki jo povzroča A. pleuropneumoniae, občutljiv za tiamulin.
Meat and offal: 2 days (8.8 mg tiamulin hydrogen fumarate (equivalent to 19.6 mg of product)/kg body weight)
Meso in organi: 2 dni (8,8 mg tiamulinijevega hidrogenfumarata (kar ustreza 19,6 mg zdravila)/kg telesne mase).
• Treatment and metaphylaxis of Enzootic Pneumonia caused by M. hyopneumoniae, including infections complicated by P. multocida susceptible to tiamulin.
• Zdravljenje in metafilaksa enzootske pljučnice, ki jo povzroča M. hyopneumoniae, vključno z okužbami, ki se zapletejo zaradi bakterije P. multocida, občutljive za tiamulin.
Name of the veterinary medicinal product Denagard 450 mg/g granules for use in drinking water for pigs, chickens and turkeys Tiamulin hydrogen fumarate
Denagard 450 mg/g zrnca za uporabo v pitni vodi za prašiče, piščance in purane tiamulinijev hidrogenfumarat
Meat and offal: 4 days (20 mg tiamulin hydrogen fumarate (equivalent to 44.4 mg of product)/kg body weight)
Meso in organi: 4 dni (20 mg tiamulinijevega hidrogenfumarata (kar ustreza 44,4 mg zdravila)/kg telesne mase).
Similar findings were reported from other studies dating from 1997 - 2014 with MIC50 ranging from ≤0.015 µg/ml - 0.06 µg/ml, MIC90 ranging from 0.031 µg/ml - 0,125 µg/ml, and MIC ranges of 0.002-0.125 µg/ml.
O podobnih izsledkih so poročali iz drugih študij, izvedenih v obdobju med letoma 1997 in 2014, pri čemer je bil razpon MIK50 med ≤ 0,015 µg/ml in 0,06 µg/ml, MIK90 v razponu med
Oral, administered in drinking water
peroralna uporaba, dajanje v vodo za pitje
• Treatment of Porcine Colonic Spirochaetosis (colitis) caused by B. pilosicoli susceptible to tiamulin.
• Zdravljenje spirohetoze debelega črevesa (kolitisa) pri prašičih, ki jo povzroča B. pilosicoli, občutljiva za tiamulin.
Doses administered ranged from 8.8-20 mg tiamulin hydrogen fumarate/kg body weight for 5 days.
Odmerki so bili v razponu med 8,8 in 20 mg tiamulinijevega hidrogenfumarata/kg telesne mase, dajali pa so jih v obdobju 5 dni.
Denagard 450 mg/g granulát na perorálny roztok
Denagard 450 mg/g granulát na perorálny roztok tiamulinijev hidrogenfumarat
• Meat and offal: 2 days (when the administered dose is 8.8 mg tiamulin hydrogen fumarate (equivalent to 19.6 mg of product)/kg body weight)
• Meso in organi: 2 dni (ob uporabi odmerka 8,8 mg tiamulinijevega hidrogenfumarata (kar ustreza 19,6 mg zdravila)/kg telesne mase)
Tiamutin 45% PigsChicken-Turkey
Tiamutin 45% PigsChicken-Turkey tiamulinijev hidrogenfumarat
From these data the CVMP concluded that Denagard 45% at a dose of 20 mg tiamulin hydrogen fumarate (equivalent to 44.4 mg of product)/kg body weight for five consecutive days would be efficacious in the treatment Pleuropneumonia caused by A. pleuropneumoniae.
Na podlagi teh podatkov je odbor CVMP zaključil, da je zdravilo Denagard 45% v odmerku 20 mg tiamulinijevega hidrogenfumarata (kar ustreza 44,4 mg zdravila)/kg telesne mase v obdobju petih dni zaporedoma učinkovito pri zdravljenju plevropnevmonije, ki jo povzroča A. pleuropneumoniae.
• Meat and offal: 4 days (when the administered dose is 20 mg tiamulin hydrogen fumarate (equivalent to 44.4 mg of product)/kg body weight)
• Meso in organi: 4 dni (ob uporabi odmerka 20 mg tiamulinijevega hidrogenfumarata (kar ustreza 44,4 mg zdravila)/kg telesne mase)
Target species turkeys, indications and posology
Ciljna vrsta purani, indikacije in način odmerjanja
Meat and offal: 2 days Eggs:
Meso in organi: 2 dni.
Pigs - Treatment of Swine Dysentery caused by Brachyspira hyodysenteriae susceptible to tiamulin.
Prašiči - Zdravljenje prašičje dizenterije, ki jo povzroča Brachyspira hyodysenteriae, občutljiva na tiamulin.
6.1 List of excipients
FARMACEVTSKI PODATKI 6.1 Seznam pomožnih snovi laktoza
The dosage is 25 mg tiamulin hydrogen fumarate (equivalent to 55.6 mg of product)/kg body weight administered daily for the period of 3 to 5 consecutive days.
Odmerek je 25 mg tiamulinijevega hidrogenfumarata (kar ustreza 55,6 mg zdravila)/kg telesne mase na dan od 3 do 5 dni zaporedoma.
• Treatment and metaphylaxis of Chronic Respiratory Disease caused by M. gallisepticum and Airsacculitis and Infectious Synovitis caused by M. synoviae susceptible to tiamulin.
• Zdravljenje in metafilaksa kronične respiratorne bolezni, ki jo povzroča M. gallisepticum, ter vnetja zračnih vrečk in infekcijskega sinovitisa, ki ju povzroča M. synoviae, občutljiva za tiamulin.
PHARMACEUTICAL FORM Granules for use in drinking water White to pale yellow granules
FARMACEVTSKA OBLIKA Zrnca za uporabo v pitni vodi.
Denagard 450 mg/g granulado oral para suínos, galinhas e perus
Denagard 450 mg/g granulado oral para suínos, galinhas e perus tiamulinijev hidrogenfumarat
- Dosage: 25 mg tiamulin hydrogen fumarate (equivalent to 55.6 mg of product)/kg body weight administered daily for 3 to 5 consecutive days.
- Odmerjanje: Dnevni odmerek 25 mg tiamulinijevega hidrogenfumarata (kar ustreza 55,6 mg zdravila)/kg telesne mase v obdobju 3 do 5 dni zaporedoma.
Pigs i) Treatment of Swine Dysentery caused by Brachyspira hyodysenteriae susceptible to tiamulin.
Prašiči i) Zdravljenje prašičje dizenterije, ki jo povzroča Brachyspira hyodysenteriae, občutljiva na tiamulin.
The dosage is 20 mg tiamulin hydrogen fumarate (equivalent to 44.4 mg of product)/kg body weight administered daily for 5 consecutive days.
Odmerek je 20 mg tiamulinijevega hidrogenfumarata (kar ustreza 44,4 mg zdravila)/kg telesne mase na dan 5 dni zaporedoma.
Treatment and metaphylaxis of Infectious Sinusitis and Airsacculitis caused by Mycoplasma gallisepticum, Mycoplasma synoviae and Mycoplasma meleagridis susceptible to tiamulin.
Zdravljenje in metafilaksa infekcijskega sinusitisa in vnetja zračnih vrečk, ki ju povzročajo Mycoplasma gallisepticum, Mycoplasma synoviae in Mycoplasma meleagridis, občutljive za tiamulin.
The liver residue data were subjected to log-linear regression using the WT1.4 calculation program and the resulting withdrawal period was 42 hours, rounded up to two days.
Podatke o ostankih v jetrih so obdelali z logistično linearno regresijo z računskim programom WT1.4.
Treatment of Swine Dysentery caused by Brachyspira hyodysenteriae susceptible to tiamulin.
Zdravljenje prašičje dizenterije, ki jo povzroča Brachyspira hyodysenteriae, občutljiva za tiamulin.
DENAGARD 45 %, vandenyje tirpios granulės
DENAGARD 45 %, vandenyje tirpios granulės tiamulinijev hidrogenfumarat
Animal species
zdravljenih živali
The dosage is 8.8 mg tiamulin hydrogen fumarate (equivalent to 19.6 mg of product)/kg body weight daily administered in the drinking water of pigs for 3 to 5 consecutive days depending on the severity of the infection and/or the duration of the disease.
Odmerek je 8,8 mg tiamulinijevega hidrogenfumarata (kar ustreza 19,6 mg zdravila)/kg telesne mase na dan, ki se daje prašičem v vodo za pitje od 3 do 5 dni zaporedoma, odvisno od resnosti okužbe in/ali trajanja bolezni.
NAME OF THE VETERINARY MEDICINAL PRODUCT Denagard 450 mg/g granules for use in drinking water for pigs, chickens and turkeys
Denagard 450 mg/g zrnca za uporabo v pitni vodi za prašiče, piščance in purane
The dosage is 40 mg tiamulin hydrogen fumarate (equivalent to 88.9 mg of product)/kg body weight daily administered for the period of 3 to 5 consecutive days.
Odmerek je 40 mg tiamulinijevega hidrogenfumarata (kar ustreza 88,9 mg zdravila)/kg telesne mase na dan od 3 do 5 dni zaporedoma.
- Dosage: 8.8 mg tiamulin hydrogen fumarate (equivalent to 19.6 mg of product)/kg body weight administered daily in the drinking water of pigs for 3 to 5 consecutive days depending on the severity of the infection and/or the duration of the disease.
- Odmerjanje: Dnevni odmerek 8,8 mg tiamulinijevega hidrogenfumarata (kar ustreza 19,6 mg zdravila)/kg telesne mase v pitni vodi za prašiče v obdobju 3 do 5 dni zaporedoma, odvisno od resnosti okužbe in/ali trajanja bolezni.
The dosage is 8.8 mg tiamulin hydrogen fumarate (equivalent to 19.6 mg of product)/kg body weight daily administered in the drinking water of pigs for 5 consecutive days.
Odmerek je 8,8 mg tiamulinijevega hidrogenfumarata (kar ustreza 19,6 mg zdravila)/kg telesne mase na dan, ki se daje prašičem v vodo za pitje 5 dni zaporedoma.
Tiamutin 45% ChickenTurkey
Tiamutin 45% ChickenTurkey tiamulinijev hidrogenfumarat
From these data the CVMP concluded that Denagard 45% at a dose of 8.8 mg tiamulin hydrogen fumarate (equivalent to 19.6 mg of product)/kg body weight for five consecutive days would be efficacious in the treatment of Porcine Proliferative Enteropathy (ileitis) caused by L. intracellularis.
Na podlagi teh podatkov je odbor CVMP zaključil, da je zdravilo Denagard 45% v odmerku 8,8 mg tiamulinijevega hidrogenfumarata (kar ustreza 19,6 mg zdravila)/kg telesne mase v obdobju petih dni zaporedoma učinkovito pri zdravljenju prašičje proliferativne enteropatije (ileitisa), ki jo povzroča L. intracellularis.
450 mg/g Powder for use in drinking water
450 mg/g zrnca za uporabo v pitni vodi prašiči peroralna uporaba
For the treatment and metaphylaxis of Chronic Respiratory Disease caused by Mycoplasma gallisepticum and Airsacculitis and Infectious Synovitis caused by Mycoplasma synoviae.
Za zdravljenje in metafilakso kronične bolezni dihal, ki jo povzroča Mycoplasma gallisepticum, ter vnetja zračnih vreč in infekcijskega sinovitisa, ki ju povzroča Mycoplasma synoviae.
- Dosage: 8.8 mg tiamulin hydrogen fumarate (equivalent to 19.6 mg of product)/kg body weight administered daily in the drinking water of pigs for 5 consecutive days.
- Odmerjanje: Dnevni odmerek 8,8 mg tiamulinijevega hidrogenfumarata (kar ustreza 19,6 mg zdravila)/kg telesne mase v pitni vodi za prašiče v obdobju 5 dni zaporedoma.
- Dosage: 40 mg tiamulin hydrogen fumarate (equivalent to 88.9 mg of product)/kg body weight administered daily for 3 to 5 consecutive days.
- Odmerjanje: Dnevni odmerek 40 mg tiamulinijevega hidrogenfumarata (kar ustreza 88,9 mg zdravila)/kg telesne mase v obdobju 3 do 5 dni zaporedoma.
Treatment of Porcine Proliferative Enteropathy (ileitis) caused by Lawsonia intracellularis susceptible to tiamulin.
Zdravljenje prašičje proliferativne enteropatije (ileitisa), ki jo povzroča Lawsonia intracellularis, občutljiva za tiamulin.