natgillin/translations-raw huggingface dataset:
The use of Tamiflu may be considered during pregnancy if necessary and after considering the available safety and benefit information (for data on benefit in pregnant women please refer to section 5.1 “treatment of influenza in pregnant women”), and the pathogenicity of the circulating influenza virus strain.
Pri tem je treba upoštevati razpoložljive informacije o varnosti in koristih (za podatke o koristih pri nosečnicah glejte poglavje 5.1 “Zdravljenje gripe pri nosečnicah”) ter patogenost krožečega seva virusa gripe.
5 ml oseltamivir suspension delivers 0.9 g of sorbitol.
5 ml suspenzije oseltamivir vsebuje 0,9 g sorbitola.
≤ 7 kg up to 40 ml
£ 7 kg do 40 ml
Paediatric population (infants less than one year of age) In two studies to characterise the pharmacokinetics, pharmacodynamics and safety profile of oseltamivir therapy in 135 influenza infected children less than one year of age, the safety profile was similar among age cohorts with vomiting, diarrohea and diaper rash being the most frequently reported adverse events (see section 5.2).
V dveh študijah, v katerih so opredelili farmakokinetiko, farmakodinamiko in varnostni profil oseltamivirja pri 135 z gripo okuženih otrocih, mlajših od 1 leta, je bil varnostni profil med vsemi starostnimi skupinami podoben, z bruhanjem, drisko in pleničnim izpuščajem kot najbolj pogosto poročanimi neželenimi učinki (glejte poglavje 5.2).
INFORMATION IN BRAILLE tamiflu 45 mg
PODATKI V BRAILLOVI PISAVI tamiflu 45 mg
The following age-adjusted dosing prophylaxis regimen is recommended for infants 0 - 12 months of age (see Section 5.2 for exposure simulation):
0 do 12 mesecev (za simulacijo izpostavljenosti glejte poglavje 5.2), je: Starost
• Tympanic membrane (eardrum) disorder.
· okvara membrane tympani (ušesnega bobniča).
Tamiflu 6 mg/ml powder for oral suspension oseltamivir
Tamiflu 6 mg/ml prašek za peroralno suspenzijo oseltamivir
Prophylaxis of influenza in immunocompromised patients: A double-blind, placebo-controlled, randomised study was conducted for seasonal prophylaxis of influenza in 475 immunocompromised patients (388 patients with solid organ transplantation [195 placebo; 193 oseltamivir], 87 patients with haemopoetic stem cell transplantation [43 placebo; 44 oseltamivir], no patient with other immunosuppressant conditions), including 18 children 1 to 12 years of age.
bolnikov s presajenimi parenhimskimi organi [195 bolnikov je prejemalo placebo, 193 pa oseltamivir], 87 bolnikov s presajenimi krvotvornimi matičnimi celicami [43 bolnikov je prejemalo placebo, 44 pa oseltamivir], bolnikov z drugimi stanji, ki bi zmanjšale imunski odziv, ni bilo) vključno z 18 otroki, starimi od 1 do 12 let, so opravili dvojno slepo, s placebom nadzorovano, randomizirano študijo za sezonsko preprečevanje gripe.
• Sweet food to hide the bitter taste of the powder.
· vodo, · sladko hrano, ki bo zakrila grenak okus praška.
When Tamiflu powder for oral suspension is not available Commercially manufactured Tamiflu for oral suspension (6 mg/ml) is the preferred product for paediatric and adult patients who have difficulties swallowing capsules or where lower doses are needed.
Kadar zdravila Tamiflu prašek za peroralno suspenzijo ni na voljo Komercialno izdelano zdravilo Tamiflu prašek za peroralno suspenzijo (6 mg/ml) je najbolj primerna oblika za pediatrične in odrasle bolnike, ki imajo težave pri požiranju kapsul ali kjer so potrebni manjši odmerki.
The following serious side effects have been rarely reported since oseltamivir has been marketed:
Odkar je oseltamivir na tržišču, so o naslednjih resnih neželenih učinkih poročali redko:
Children weighing > 40 kg and who are able to swallow capsules may receive prophylaxis with a 75 mg capsule once daily for 10 days as an alternative to the recommended dose of Tamiflu suspension.
Otroci, ki tehtajo več kot 40 kg in zmorejo pogoltniti kapsulo, lahko za preprečevanje gripe namesto priporočenega odmerka suspenzije zdravila Tamiflu prejmejo 75-mg kapsule enkrat na dan 10 dni.
Yellow iron oxide (E172) Red iron oxide (E172) Black iron oxide (E172) Titanium dioxide (E171)
rdeči železov oksid (E172) črni železov oksid (E172)
For doses above 3.0 ml to 10 ml, 10 ml oral dispenser should be used.
Za odmerke od 3,0 ml do 10 ml je potrebno uporabiti 10-ml peroralni odmernik.
More than 23 kg, up to 40 kg
Več kot 23 kg in do 40 kg
More than 15 kg, up to 23 kg
Več kot 15 kg in do 23 kg
Other medicines and Tamiflu Tell your doctor or pharmacist if you are taking any other medicines, or have recently taken any.
Obvestite zdravnika ali farmacevta, če jemljete ali ste pred kratkim jemali katero koli drugo zdravilo,
Infants less than 1 year (including full-term newborn babies) Child's weight (nearest)
Dojenčki, stari manj kot 1 leto (vključno z donošenimi novorojenčki) Otrokova telesna masa (najbližja)
Do not try to make a 30 mg, 60 mg or 75 mg dose by using the contents of 45 mg capsules.
Ne poskušajte narediti 30-mg, 60mg ali 75-mg odmerka z uporabo vsebine iz 45-mg kapsul, temveč uporabite kapsule z ustreznim odmerkom.
The following weight-adjusted dosing regimens are recommended for infants and children 1 year of age or older:
Priporočeno odmerjanje glede na telesno maso za dojenčke in otroke, stare 1 leto in več, je:
Oseltamivir is readily absorbed from the gastrointestinal tract after oral administration of oseltamivir phosphate (pro-drug) and is extensively converted by predominantly hepatic esterases to the active metabolite (oseltamivir carboxylate).
Oseltamivir se po peroralnem zaužitju oseltamivirjevega fosfata (predzdravila) hitro absorbira iz gastrointestinalnega trakta in se znatno večinoma z jetrnimi esterazami pretvori v aktivni presnovek
Prevention during an influenza epidemic in the community: In a pooled analysis of two other studies conducted in unvaccinated otherwise healthy adults, oseltamivir 75 mg once daily given for 6 weeks significantly reduced the incidence of clinical influenza illness from 25/519 (4.8 %) in the placebo group to 6/520 (1.2 %) in the oseltamivir group (76 % reduction [95 % CI 1.6 - 5.7; p = 0.0006]) during a community outbreak of influenza.
Preprečevanje gripe med epidemijo v okolici: skupna analiza dveh drugih študij, ki so ju opravili pri necepljenih, sicer zdravih odraslih, ki so prejemali 75 mg oseltamivirja enkrat na dan 6 tednov, je pokazala pomembno zmanjšanje pogostnosti klinične oblike gripe v skupini, ki je jemala oseltamivir med izbruhom gripe v okolici (6/520 (1,2 %)) v primerjavi s placebo skupino (25/519, (4,8 %)) (76 % zmanjšanje [95-% interval zaupanja 1,6-5,7; p = 0,0006]).
Pharmacy compounded 6 mg/ml suspension prepared from capsules
Preglednica za odmerjanje 6 mg/ml suspenzije, pripravljene v lekarni, iz kapsul zdravila
Children weighing > 40 kg and who are able to swallow capsules may receive treatment with the adult dosage of 75 mg capsules twice daily for 5 days as an alternative to the recommended dose of Tamiflu suspension.
Otroci, ki tehtajo več kot 40 kg in zmorejo pogoltniti kapsulo, lahko namesto priporočenega odmerka suspenzije zdravila Tamiflu prejmejo odmerek za odrasle - 75-mg kapsulo dvakrat na dan 5 dni.
Tamiflu can be taken with or without food, although taking it with food can reduce the chance of feeling or being sick (nausea or vomiting).
Jemanje s hrano zmanjša možnost slabega počutja (siljenje na bruhanje ali bruhanje).
Store the medicine below 25 º C for up to 10 days.
Zdravilo shranjujte do 10 dni pri temperaturi do 25 °C.
Push the tip of the dispenser into the bottle adapter.
Pritisnite vrh odmernika v nastavek za steklenico.
In the total population, there was a reduction in the incidence of laboratory-confirmed clinical influenza in households from 20 % (27/136) in the group not receiving prevention to 7 % (10/135) in the group receiving prevention (62.7 % reduction [95 % CI 26.0 - 81.2; p = 0.0042]).
V celotni populaciji je bilo zmanjšanje v pojavnosti klinične laboratorijsko potrjene influence v gospodinjstvu iz 20 % (27/136) v skupini, ki ni prejemala zdravila za preprečevanje, na 7 % (10/135) v skupini, ki je prejemala zdravilo za preprečevanje (62,7-% znižanje [95-% interval zaupanja 26,0 - 81,21; p = 0,0042]).
Tamiflu 75 mg hard capsules are available in blister packs of 10.
Trde kapsule zdravila Tamiflu 75 mg so na voljo v pretisnih omotih po 10 kapsul.
Tamiflu 30 mg hard capsules are available in blister packs of 10.
Trde kapsule zdravila Tamiflu 30 mg so na voljo v pretisnih omotih po 10 kapsul.
The proportion of subjects who developed specified lower respiratory tract complications (mainly bronchitis) treated with antibiotics was reduced from 12.7 % (135/1,063) in the placebo group to 8.6 % (116/1,350) in the oseltamivir treated population (p = 0.0012).
Odstotek bolnikov, pri katerih so se pojavili opisani zapleti v spodnjem delu respiratornega trakta (v glavnem bronhitis) in so se zdravili z antibiotiki, je bil v placebo skupini 12,7 % (135/1063), v skupini, ki se je zdravila z oseltamivirjem, pa 8,6 % (116/1350; p = 0,0012).
Tamiflu 75 mg hard capsules 10 years
Tamiflu 75 mg trde kapsule 10 let
What Tamiflu looks like and contents of the pack The 45 mg hard capsule consists of a grey opaque body bearing the imprint “ROCHE” and a grey opaque cap bearing the imprint “45 mg”.
Izgled zdravila Tamiflu in vsebina pakiranja 45 mg trda kapsula ima sivo neprozorno telo z napisom “ROCHE” in siv neprozoren pokrov z napisom “45 mg”.
30 mg (suspension or capsules) once daily
30 mg (suspenzija ali kapsula) enkrat na dan
- Tamiflu is indicated for post-exposure prevention of influenza in infants less than 1 year of age during a pandemic influenza outbreak (see section 5.2).
mlajših od 1 leta, med izbruhom pandemije gripe (glejte poglavje 5.2).
The following dosing regimen is recommended for treatment of infants below 1 year of age:
Za dojenčke, stare manj kot 1 leto, se priporoča naslednji režim odmerjanja:
What Tamiflu contains
Kaj vsebuje zdravilo Tamiflu
NAME OF THE MEDICINAL PRODUCT Tamiflu 6 mg/ml powder for oral suspension
IME ZDRAVILA Tamiflu 6 mg/ml prašek za peroralno suspenzijo
Use the larger dispenser draw up 7.5 ml water.
s katerim boste odmerili 7,5 ml vode.
How to take Tamiflu
Kako jemati zdravilo Tamiflu
A study in older people in nursing homes, where 80 % of participants received vaccine in the season of the study, oseltamivir 75 mg once daily given for 6 weeks significantly reduced the incidence of clinical influenza illness from 12/272 (4.4 %) in the placebo group to 1/276 (0.4 %) in the oseltamivir group (92 % reduction [95 % CI 1.5 - 6.6; p = 0.0015]).
Študija med starejšimi ljudmi v domovih za ostarele, kjer je 80 % udeležencev prejelo cepivo v sezoni, ko je potekala študija, je pri jemanju oseltamivirja v odmerku 75 mg enkrat na dan 6 tednov, pokazala pomembno zmanjšanje pogostnosti klinične oblike gripe (1/276 (0,4 %)) v primerjavi s placebo skupino (12/272 (4,4 %)) (92-% zmanjšanje [95-% interval zaupanja 1,5-6,6; p = 0,0015]).
10 capsules (300 mg)
10 kapsul (300 mg)
• Add all the water, close and shake Pour all of the water from the jug into the bottle, onto the powder.
Vso vodo iz čaše prelijte v steklenico, na prašek.
• For doses from 1.0 ml to 3.0 ml, the 3 ml oral dispenser should be used.
Za odmerke od 1,0 ml do 3,0 ml je potrebno uporabiti 3-ml peroralni odmernik.
See the instructions overleaf to make up and give a dose.
Glejte navodilo za pripravo in odmerjanje na naslednjih straneh.
• Nausea.
· bolečina,
What Tamiflu looks like and contents of the pack The 30 mg hard capsule consists of a light yellow opaque body bearing the imprint “ROCHE” and a light yellow opaque cap bearing the imprint “30 mg”.
Izgled zdravila Tamiflu in vsebina pakiranja 30-mg trda kapsula ima svetlo rumeno neprozorno telo z napisom “ROCHE” in svetlo rumen neprozoren pokrov z napisom “30 mg”.
Tamiflu 45 mg hard capsules 10 years
Tamiflu 45 mg trde kapsule 10 let
1 bottle contains 390 mg of oseltamivir.
NAVEDBA ENE ALI VEČ UČINKOVIN 1 steklenica vsebuje 390 mg oseltamivirja.
10 ml oseltamivir suspension delivers 1.7 g of sorbitol.
10 ml suspenzije oseltamivir vsebuje 1,7 g sorbitola.
See Making liquid Tamiflu at home, over the page.
Za navodila glejte Priprava tekočega zdravila Tamiflu doma na naslednjih straneh.
For measuring 12.5 ml of water a 10 ml dispenser should be used.
Za odmerjanje 12,5 ml vode se mora uporabiti 10-ml odmernik.
7.5 ml oseltamivir suspension delivers 1.3 g of sorbitol.
7,5 ml suspenzije oseltamivir vsebuje 1,3 g sorbitola.
The following serious adverse reactions have been rarely reported since oseltamivir has been marketed: Anaphylactic and anaphylactoid reactions, hepatic disorders (fulminant hepatitis, hepatic function disorder and jaundice), angioneurotic oedema, Stevens-Johnson syndrome and toxic epidermal necrolysis, gastrointestinal bleeding and neuropsychiatric disorders.
Odkar je oseltamivir na tržišču, so o naslednjih resnih neželenih učinkih poročali redko: anafilaktične in anafilaktoidne reakcije, bolezni jeter (fulminantni hepatitis, moteno delovanje jeter in zlatenica),
D- 79639 Grenzach -Wyhlen Germany
D-79639 Grenzach-Wyhlen Nemčija
• Depending on the required dose you will need the 3 ml oral dispenser (yellow plunger, 0.1 ml graduation) or the 10 ml oral dispenser (white plunger 0.5 ml graduation) from the medicine pack.
Potrebovali boste: · steklenico s pripravljeno peroralno suspenzijo zdravila Tamiflu, · Glede na potrebni odmerek boste potrebovali 3-ml peroralni odmernik (rumeni bat, skala po 0,1 ml) ali 10-ml peroralni odmernik (bel bat, skala po 0,5 ml), priložen v pakiranju.
Shake the suspension well and draw the appropriate recommended dose into the dispenser.
Faza 2 Odmerite in dajte pravi odmerek Suspenzijo dobro pretresite in dajte priporočeni odmerek v odmernik.
Turn the whole unit upright.
Potisnite bat navzdol proti vrhu odmernika.
12.5 ml oseltamivir suspension delivers 2.1 g of sorbitol.
12,5 ml suspenzije oseltamivir vsebuje 2,1 g sorbitola.
In a pooled analysis of all influenza-positive adults and adolescents (N = 2,413) enrolled into treatment studies, oseltamivir 75 mg twice daily for 5 days reduced the median duration of influenza illness by approximately one day from 5.2 days (95 % CI 4.9 - 5.5 days) in the placebo group to 4.2 days (95 % CI 4.0 - 4.4 days; p ≤ 0.0001).
75 mg dvakrat na dan 5 dni, je bila mediana trajanja okužbe z virusom influence zmanjšana za približno en dan - s 5,2 dneva (95-% interval zaupanja 4,9-5,5 dni) v placebo skupini na 4,2 dni (95% interval zaupanja 4,0-4,4 dni; p ≤ 0,0001).
Do not try to make a 45 mg or 75 mg dose by using the contents of 30 mg capsules.
Ne poskušajte narediti 45-mg ali 75-mg odmerka z uporabo vsebine iz 30-mg kapsul, temveč uporabite kapsule z ustreznim odmerkom.
A 3 ml oral dispenser (graduated in 0.1 ml steps) should be used for dosing children 0 - 12 months of age requiring 1 ml to 3 ml of Tamiflu 6 mg/ml oral suspension.
Pri odmerjanju otrokom, starim od 0 do 12 mesecev, ki potrebujejo 1 ml do 3 ml zdravila Tamiflu 6 mg/ml peroralne suspenzije, je potrebno uporabiti 3-ml peroralni odmernik (z oznakami po 0,1 ml).
Tamiflu 30 mg and 45 mg capsules are available as an alternative to the recommended dose of Tamiflu 6 mg/ml suspension.
Tamiflu 6 mg/ml so na voljo 30-mg in 45-mg kapsule zdravila Tamiflu.
Tamiflu 30 mg hard capsules
Tamiflu 30 mg trde kapsule
For storage conditions of the pharmacy compounded suspension, see section 6.3.
Za pogoje shranjevanja suspenzije, pripravljene v lekarni, glejte poglavje 6.3. 6.5 Vrsta ovojnine in vsebina
Among children who were not already shedding virus at baseline, the incidence of laboratory-confirmed clinical influenza was reduced from 21 % (15/70) in the group not receiving prevention to 4 % (2/47) in the group receiving prevention (80.1 % reduction [95 % CI 22.0 - 94.9; p = 0.0206]).
V študiji se je incidenca klinične laboratorijsko potrjene influence pri otrocih, ki še niso izločali virusa na začetku, zmanjšala iz 21 % (15/70) v skupini, ki ni prejemala zdravila za preprečevanje, na 4 % (2/47) v skupini, ki je prejemala zdravilo za preprečevanje gripe (80,1-% zmanjšanje [95-% interval zaupanja 22,0-94,9; p = 0,0206]).
Eczema, Dermatitis, Rash, Urticaria
Bolezni jeter, žolčnika in žolčevodov
MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS Label for bottle
zaporka nastavek za steklenico merilna čaša oznaka
For infants less than 1 year of age: The recommended prophylaxis dose for infants less than 12 months during a pandemic influenza outbreak is half of the daily treatment dose.
mlajših od 1 leta, je polovica dnevnega odmerka za zdravljenje med izbruhom pandemije gripe.
In influenza-positive older people , oseltamivir significantly reduced the incidence of specified lower respiratory tract complications (mainly bronchitis) treated with antibiotics from 19 % (52/268) in the placebo group to 12 % (29/250) in the oseltamivir treated population (p = 0.0156).
Pri starejših bolnikih, okuženih z virusom influence, je bila pogostnost specifičnih zapletov spodnjega respiratornega trakta (v glavnem bronhitisa), zdravljenih z antibiotiki, v skupini, ki je prejemala oseltamivir, pomembno zmanjšana v primerjavi s skupino, ki je jemala placebo (12 % (29/250) proti 19 % (52/268); p = 0,0156).
Tamiflu 45 mg hard capsules are available in blister packs of 10.
Trde kapsule zdravila Tamiflu 45 mg so na voljo v pretisnih omotih po 10 kapsul.
• Runny nose
• izcedek iz nosu,
Use the larger dispenser to draw up 5 ml water.
s katerim boste odmerili 5 ml vode.
• One small oral dose dispenser showing measurements of 0.1 ml, to give the dose
· velik peroralni odmernik za odmerjanje vode - 5- ali 10-ml odmernik, · majhen peroralni odmernik z oznakami za odmerjanje po 0,1 ml za dajanje odmerka zdravila,
Oseltamivir significantly reduced the incidence of clinical influenza illness occurring in the contacts of confirmed influenza cases from 24/200 (12 %) in the placebo group to 2/205 (1 %) in the oseltamivir group (92 % reduction [95 % CI 6 - 16; p ≤ 0.0001]).
V skupini, ki je jemala oseltamivir, je bila pogostnost pojava klinične gripe, ki se je pojavila po stiku z bolniki, okuženimi z virusom influence, pomembno zmanjšana (2/205 (1 %) v primerjavi s placebo skupino (24/200 (12 %)) (92-% zmanjšanje [95-% interval zaupanja 6-16; p ≤ 0,0001]).
The hard capsule consists of a light yellow opaque body bearing the imprint “ROCHE” and a light yellow opaque cap bearing the imprint “30 mg”.
Trda kapsula ima svetlo rumeno neprozorno telo z napisom “ROCHE” in svetlo rumen neprozoren pokrov z napisom “30 mg”.
Teratology studies have been conducted in rats and rabbits at doses of up to 1,500 mg/kg/day and 500 mg/kg/day, respectively.
Študije teratogenosti pri podganah, ki so prejemale odmerke do 1500 mg/kg/dan, in pri kuncih, ki so prejemali odmerke do 500 mg/kg/dan, niso pokazale vplivov na razvoj zarodka.
• If you have the right capsule strength for the dose needed (a 75 mg dose), you will open the capsule and stir its contents into one teaspoon (or less) of a suitable sweetened food product.
Priprava tekočega zdravila Tamiflu doma · Če imate na voljo ustrezne kapsule za odmerek, ki ga potrebujete (75-mg odmerek), boste kapsulo odprli in vsebino vmešali v eno čajno žličko (ali manj) primerne sladke hrane.
Tamiflu 75 mg hard capsules
Tamiflu 75 mg trde kapsule
A 3 ml oral dispenser (graduated in 0.1 ml steps) should be used for dosing infants less than 1 year old requiring 1 to 3 ml of Tamiflu oral suspension.
Za odmerjanje dojenčkom, mlajšim od 1 leta, ki potrebujejo 1 do 3 ml peroralne suspenzije Tamiflu, je potrebno uporabiti 3-ml peroralni odmernik (z oznakami po 0,1 ml).
• Sore throat
boleče grlo,
The hard capsule consists of a grey opaque body bearing the imprint “ROCHE” and a light yellow opaque cap bearing the imprint “75 mg”.
Trda kapsula ima sivo neprozorno telo z napisom “ROCHE” in svetlo rumen neprozoren pokrov z napisom “75 mg”.
Use the larger dispenser to draw up 12.5 ml water.
s katerim boste odmerili 12,5 ml vode.
The indication in infants below the age of 1 is based upon extrapolation of efficacy data from older children and the recommended posology is based upon pharmacokinetic modelling data (see Section
Indikacija pri dojenčkih, mlajših od 1 leta, temelji na ekstrapolaciji podatkov o učinkovitosti pri starejših otrocih.
Treatment of influenza: Dose adjustment is recommended for adults and adolescents (13 to 17 years of age) with moderate or severe renal impairment.
Zdravljenje gripe: prilagajanje odmerkov je priporočljivo za odrasle in mladostnike (stare od 13 do 17
NAME OF THE MEDICINAL PRODUCT Tamiflu 6 mg/ml powder for oral suspension Oseltamivir
IME ZDRAVILA Tamiflu 6 mg/ml prašek za peroralno suspenzijo oseltamivir
Patients with Resistance Mutations (%) Phenotyping* Geno- and Phenotyping* Adults and adolescents 0.88% (21/2377)
Bolniki z virusnimi sevi, odpornimi na oseltamivir (%) Fenotipizacija* Genotipizacija in fenotipizacija*
• Anaphylactic and anaphylactoid reactions: severe allergic reactions, with face and skin swelling, itchy rashes, low blood pressure and breathing difficulties
· anafilaktične in anafilaktoidne reakcije: hude alergijske reakcije z otekanjem obraza in kože,
There is insufficient clinical data available in infants and children (1 year of age or older) with renal impairment to be able to make any dosing recommendation (see sections 4.2 and 5.2).
Zadostnih kliničnih podatkov za pripravo priporočil o odmerjanju pri dojenčkih in otrocih (starih 1 leto ali več) z ledvično okvaro ni na voljo (glejte poglavji
Respiratory, thoracic and mediastinal disorders
Bolezni dihal, prsnega koša in mediastinalnega prostora kašelj,
In households of influenza-infected index cases, there was a reduction in the incidence of influenza from 26 % (23/89) in the group not receiving prevention to 11 % (9/84) in the group receiving prevention (58.5 % reduction [95 % CI 15.6 - 79.6; p = 0.0114]).
V gospodinjstvu s kliničnimi simptomi gripe je bilo znižanje pojavnosti influence iz 26 % (23/89) v skupini, ki ni prejemala zdravila za preprečevanje, na 11 % (9/84) v skupini, ki je prejemala zdravilo za preprečevanje (58,5-% znižanje [95-% interval zaupanja
10.0 ml twice daily 10.0 ml once daily
10 ml dvakrat na dan 10 ml enkrat na dan
• Vomiting.
• siljenje na bruhanje,
7.5 ml once daily
7,5 ml enkrat na dan
Tamiflu 45 mg hard capsules
Tamiflu 45 mg trde kapsule
The hard capsule consists of a grey opaque body bearing the imprint “ROCHE” and a grey opaque cap bearing the imprint “45 mg”.
Trda kapsula ima sivo neprozorno telo z napisom “ROCHE” in siv neprozoren pokrov z napisom “45 mg”.
• Prepare the oral dispenser
· Pripravite peroralni odmernik
12.5 ml once daily
12,5 ml enkrat na dan
• The other ingredients are: capsule contents: pregelatinised starch, talc, povidone, croscarmellose sodium and sodium stearyl fumarate capsule shell: gelatin, yellow iron oxide (E172), red iron oxide (E172), black iron oxide (E172) and titanium dioxide (E171) printing ink: shellac (E904), titanium dioxide (E171) FD and C Blue 2 (indigo carmine E132).
• Pomožne snovi so: vsebina kapsule: predgelirani škrob, smukec, povidon, natrijev premrežen karmelozat in natrijev stearilfumarat; ovojnica kapsule: želatina, rumeni železov oksid (E172), rdeči železov oksid (E172), črni železov oksid (E172) in titanov dioksid (E171); barvilo za tisk: šelak (E904), titanov dioksid (E171) in FD in C modro 2 (indigotin E132).
Prevention during an influenza epidemic in the community Prevention during an influenza epidemic has not been studied in children below 12 years of age.
Preprečevanje gripe med epidemijo v okolici Preprečevanje gripe med epidemijo v okolici ni bilo preučevano pri otrocih, mlajših od 12 let.
Treatment: The recommended oral dose is 75 mg oseltamivir twice daily for 5 days for adolescents (13 to 17 years of age) and adults.
Zdravljenje: priporočeni peroralni odmerek za mladostnike (stare od 13 do 17 let) in odrasle je 75 mg oseltamivirja dvakrat na dan 5 dni.
Stevens-Johnson syndrome, Toxic epidermal necrolysis
toksična epidermalna nekroliza
You must tell your doctor if you are breast-feeding so that your doctor can decide if Tamiflu is right for you.
Če dojite, obvestite zdravnika, ki bo odločil o tem, ali boste prejeli zdravilo Tamiflu ali ne.