natgillin/translations-raw huggingface dataset:
• Other medicines to treat depression (such as amitriptyline, nortriptyline).
• Druga zdravila za zdravljenje depresije (npr. amitriptilin, nortriptilin)
Co-administration with sertraline is not recommended
Sočasna uporaba s sertralinom ni priporočljiva
• Do not use Zoloft together with disulfiram.
• Ne jemljite zdravila Zoloft sočasno z disulfiramom.
Sertraline does not act as an inhibitor of CYP 3A4, CYP 2C9, CYP 2C19, and CYP 1A2 to a clinically significant degree.
Sertralin nima klinično pomembnega učinka kot zaviralec CYP 3A4, CYP 2C9, CYP 2C19 in CYP 1A2.
Marketing Authorisation Holder (Invented) name
Imetnik dovoljenja za promet Izmišljeno ime
Sertraline should be discontinued in any patient entering a manic phase.
Uporabo sertralina morate prekiniti, če bolnik prehaja v manično fazo.
Section 4.1 - Indications: Panic disorder with or without agoraphobia disorder
Poglavje 4.1 - Indikacije: Panična motnja z agorafobično motnjo ali brez nje
In the two positive general population trials, the male and female sertraline vs. placebo responder rates were similar (females: 57.2% vs 34.5%; males: 53.9% vs 38.2%).
V dveh pozitivnih preskušanjih, izvedenih na splošni populaciji, je bil odziv moških in žensk, zdravljenih s sertralinom v primerjavi s placebom, podoben (ženske: 57,2 % proti 34,5 %; moški: 53,9 % proti 38,2 %).
Schizophrenia Psychotic symptoms might become aggravated in schizophrenic patients.
Shizofrenija Bolnikom s shizofrenijo se lahko psihotični simptomi poslabšajo.
Table 1 displays adverse reactions observed from postmarketing experience (frequency not known) and placebo-controlled clinical trials (comprising a total of 2542 patients on sertraline and 2145 on placebo) in depression, OCD, panic disorder, PTSD and social anxiety disorder.
Preglednica 1 prikazuje neželene učinke, zabeležene med izkušnjami iz obdobja trženja (pogostnost ni znana) in v kliničnih preskušanjih, nadzorovanih s placebom (skupaj so zajela 2542 bolnikov s sertralinom in 2145 s placebom), pri depresiji, OKM, panični motnji, PTSM in socialni anksiozni motnji.
Food does not significantly change the bioavailability of sertraline tablets.
Hrana ne povzroči pomembne spremembe biološke uporabnosti tablet sertralina.
As the capsule contains the excipient lactose (see section 6.1), patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
Kapsule kot pomožno snov vsebujejo laktozo (glejte poglavje 6.1), zato bolniki z redkimi prirojenimi motnjami, kot so galaktozna intoleranca, laponska oblika zmanjšane aktivnosti laktaze ali malabsorpcija laktoze, ne smejo jemati tega zdravila.
Sertraline exhibits dose proportional pharmacokinetics in the range of 50 to 200 mg.
Sertralin ima v območju od 50 do 200 mg odmerka sorazmerno farmakokinetiko.
Anaphylactoid Reaction, Allergic Reaction, Allergy
Bolezni imunskega sistema anafilaktoidna reakcija, alergijska reakcija, alergija
In accord with its selective inhibition of 5-HT uptake, sertraline does not enhance catecholaminergic activity.
Sertralin skladno s svojim selektivnim zavrtjem privzema 5-HT ne zvečuje kateholaminergičnega delovanja.
Do not mix the concentrate with anything other than the liquids listed.
Koncentrata ne smete redčiti z ničimer drugim kot z naštetimi tekočinami.
Depression and OCD Sertraline treatment should be started at a dose of 50 mg/day.
Depresija in OKM Sertralin je treba uporabiti v odmerku 50 mg/dan.
Switching from Selective Serotonin Reuptake Inhibitors (SSRIs), antidepressants or antiobsessional drugs
Prehod s selektivnih zaviralcev ponovnega privzema serotonina (SSRI), antidepresivov ali antiobsesivnih zdravil
The active compound of Zoloft and associated names is sertraline, a selective serotonin reuptake inhibitor (SSRI).
Učinkovina zdravila Zoloft in z njim povezanih imen je sertralin, selektivni zaviralec ponovnega privzema serotonina (SSRI).
Depression, OCD, Panic Disorder, Social Anxiety Disorder and PTSD Patients not responding to a 50 mg dose may benefit from dose increases.
Depresija, OKM in panična motnja ter PTSM in socialna anksiozna motnja Bolnikom, ki se ne odzovejo na odmerek 50 mg, lahko koristi zvečanje odmerka.
In previous applications, the MAH had submitted data from a placebo-controlled withdrawal study (relapse prevention study) in which responders to 1 year open label treatment were randomised to treatment with sertraline or placebo for a duration of 28 weeks and the results from that study were considered.
V prejšnjih vlogah je imetnik dovoljenja za promet predložil podatke iz s placebom kontrolirane ukinitvene študije (študije preprečevanja ponovitev), v kateri so bili odzivni bolniki po enoletnem neslepem zdravljenju naključno izbrani za 28-tedensko zdravljenje s sertralinom ali placebom, upoštevani pa so bili rezultati te študije.
Sertraline and N-desmethylsertraline are both extensively metabolized in man and the resultant metabolites excreted in faeces and urine in equal amounts.
Pri človeku se sertralin in Ndezmetilsertralin oba izdatno presnavljata; nastali presnovki se v enakih količinah izločijo v blatu in urinu.
6.6 Special precautions for disposal and other handling No special requirements
6.6 Posebni varnostni ukrepi za odstranjevanje in ravnanje z zdravilom Ni posebnih ukrepov.
Serious liver events (including hepatitis, jaundice and liver failure)
Resni jetrni učinki (vključno s hepatitisom, zlatenico in odpovedjo jeter)
Reproduction toxicity studies in animals showed no evidence of teratogenicity or adverse effects on male fertility.
Študije vpliva na sposobnost razmnoževanja pri živalih niso pokazale teratogenega delovanja ali neželenih učinkov na plodnost samcev.
Depending on hepatic function, this effect may still be present for as long as two weeks after the last dose of disulfiram, although one week is the more typical duration of action with standard doses.
Odvisno od delovanja jeter je učinek disulfirama lahko prisoten še dva tedna po zadnjem odmerku, čeprav je običajno obdobje učinkovanja priporočenega odmerka en teden.
Capsules, hard
Trde kapsule
In clinical trials, among patients treated with sertraline, the incidence of reported withdrawal reactions was 23% in those discontinuing sertraline compared to 12% in those who continued to receive sertraline treatment.
V kliničnih preskušanjih je bila pogostnost odtegnitvenih reakcij med bolniki, ki so prenehali dobivati sertralin 23 %, med tistimi, ki so ga dobivali še naprej pa 12 %.
Co-administration of sertraline 200 mg daily with warfarin resulted in a small but statistically significant increase in prothrombin time, which may in some rare cases unbalance the INR value.
Sočasna uporaba 200 mg sertralina na dan z varfarinom je malo, a statistično pomembno podaljšala protrombinski čas, kar lahko v nekaterih redkih primerih povzroči spremembo INR.
Published data concerning sertraline levels in breast milk show that small quantities of sertraline and its metabolite N-desmethylsertraline are excreted in milk.
Objavljeni podatki o koncentraciji sertralina v materinem mleku kažejo, da se v mleko izloča majhna količina sertralina in njegovega presnovka N-dezmetilsertralina.
The % of responders (defined as those patients that did not relapse) for sertraline and placebo arms were 83.4% and 60.8%, respectively.
Odstotek odzivnih bolnikov (ti so bili opredeljeni kot bolniki, pri katerih se ni pojavil relaps) je bil v kraku s sertralinom 83,4 % in v kraku s placebom 60,8 %.
To be taken into account in pregnant or breast-feeding women, children and high-risk groups such as patients with liver disease, or epilepsy.
Vsebnost alkohola je treba upoštevati pri nosečnicah in doječih materah, otrocih in zelo ogroženih skupinah, npr. bolnikih z obolenjem jeter ali epilepsijo.
• Medicines to treat mania and depression (lithium).
• Zdravila za zdravljenje manije in depresije (litij)
Women of childbearing potential should employ an adequate method of contraception if taking sertraline.
Ženske v rodni dobi bi morale uporabljati primerno kontracepcijsko zaščito med jemanjem sertralina.
In patients with diabetes, treatment with an SSRI may alter glycaemic control, possibly due to improvement of depressive symptoms.
Zdravljenje s SSRI lahko pri sladkornih bolnikih vpliva na stanje glikemije, morda zaradi izboljšanja depresivnih simptomov.
Sertraline is not recommended in pregnancy, unless the clinical condition of the woman is such that the benefit of the treatment is expected to outweigh the potential risk.
Sertralina med nosečnostjo ni priporočljivo uporabljati, razen če je klinično stanje ženske takšno, da pričakovane koristi zdravljenja odtehtajo možno tveganje.
These undesirable effects are dose dependent and are often transient in nature with continued treatment.
Ti neželeni učinki so odvisni od odmerka in se med nadaljevanjem zdravljenja pogosto izkažejo za prehodne.
Concomitant treatment with irreversible monoamine oxidase inhibitors (MAOIs) is contraindicated due to the risk of serotonin syndrome with symptoms such as agitation, tremor and hyperthermia.
Sočasno zdravljenje z ireverzibilnimi zaviralci monoaminooksidaze (zaviralci MAO) je kontraindicirano zaradi tveganja serotoninskega sindroma s simptomi, kot so agitiranost, tremor in hipertermija.
There is evidence that sertraline is excreted in human breast milk.
Podatki kažejo, da se sertralin pri človeku izloča v materino mleko.
Panic Disorder, PTSD, and Social Anxiety Disorder Therapy should be initiated at 25 mg/day.
Panična motnja, PTSM in socialna anksiozna motnja Zdravljenje je treba začeti s 25 mg/dan.
Sertraline concentrate for oral solution contains 20 mg/ml of sertraline.
Sertralin koncentrat za peroralno raztopino vsebuje 20 mg sertralina/ml.
Paediatric patients with OCD
Pediatrični bolniki z OKM
What Zoloft is and what it is used for.
Kaj je zdravilo Zoloft in za kaj ga uporabljamo 2.
The risk of withdrawal symptoms depends on the length of treatment, dosage, and the rate at which the dose is reduced.
Tveganje za odtegnitveno reakcijo je odvisno od dolžine zdravljenja, odmerka in hitrosti zmanjševanja odmerka.
• Medicines to treat schizophrenia and other mental disorders (such as perphenazine,
• Zdravila za zdravljenje shizofrenije in drugih duševnih motenj (npr. perfenazin,
In patients with liver damage, the half life of sertraline is prolonged and AUC is increased three fold (see sections 4.2 and 4.4).
Pri bolnikih z okvaro jeter je podaljšan razpolovni čas sertralina, AUC pa je približno trikrat večji (glejte poglavje 4.2 in 4.4).
A review of the trials included in this dossier indicated that there were two trials that included patients with a bipolar disorder and one with depression accompanied by symptoms of anxiety.
Pregled študij, vključenih v to dokumentacijo, je pokazal, da so bili v dve študiji vključeni bolniki z bipolarno motnjo, v eno študijo pa depresivni bolniki s spremljajočimi znaki anksioznosti.
Adolescents and elderly
Mladostniki in odrasli
Nausea is the most common undesirable effect.
Najpogostejši neželeni učinek je navzea.
In patients with moderate-severe renal impairment, there was no significant accumulation of sertraline.
Okvara ledvic Pri bolnikih z zmerno ali hudo okvaro ledvic ni bilo pomembnega kopičenja sertralina.
• Diabetes; your blood glucose levels may be altered due to Zoloft and your diabetes medicines may need to be adjusted.
• Sladkorna bolezen; zaradi jemanja zdravila Zoloft se lahko spremeni nivo glukoze v krvi, zato je potrebno prilagoditi odmerek zdravila za zdravljenje sladkorne bolezni.
Induction of emesis is not recommended.
Sprožitev bruhanja ni priporočljiva.
The results submitted indicated that only 6 patients relapsed during the withdrawal phase of this study, 6% in placebo and 1% in the sertraline arm.
Predloženi rezultati so pokazali, da je bilo zdravljenje med ukinitvenim obdobjem študije neuspešno pri le 6 bolnikih, pri 6 % oseb, zdravljenih s placebom, in pri 1 % tistih, zdravljenih s sertralinom.
If concomitant treatment with sertraline and triptans is clinically warranted, appropriate observation of the patient is advised (see section 4.4).
Če je sočasna uporaba sertralina in triptanov klinično potrebna, je treba bolnika ustrezno nadzorovati (glejte poglavje 4.4).
A multiple dose pharmacokinetic study in subjects with mild, stable cirrhosis demonstrated a prolonged elimination half life and approximately threefold greater AUC and Cmax in comparison to normal subjects.
Farmakokinetična študija več odmerkov pri preiskovancih z blago, stabilno cirozo je pokazala, da je razpolovni čas izločanja pri njih podaljšan, AUC in Cmax pa sta približno trikrat večji kot pri zdravih preiskovancih.
In general, the CHMP considered the wordings proposed by the MAH to be acceptable.
Na splošno je CHMP menil, da je besedilo, ki ga je predlagal imetnik dovoljenja za promet z zdravilom, sprejemljivo.
“Sertraline is indicated for the treatment of major depressive episodes.
„Sertralin je indiciran za zdravljenje hudih depresivnih epizod.
However, the generally lower body weights of children compared to those of adults should be taken into consideration when increasing the dose from 50 mg.
Vendar je v splošnem treba pri povečevanju 50-miligramskega odmerka upoštevati nižjo telesno maso otrok v primerjavi z odraslimi.
If you have a manic episode, contact your doctor immediately.
Če imate manični napad takoj obvestite svojega zdravnika.
In vitro studies indicate that sertraline has little or no potential to inhibit CYP 1A2.
Študije in vitro kažejo, da sertralin zavira CYP 1A2 le malo ali sploh ne.
Following treatment with a reversible MAO-inhibitor, a shorter withdrawal period than 14 days may be used before initiation of sertraline treatment.
Po zdravljenju z reverzibilnim zaviralcem MAO je lahko obdobje prekinitve pred uvedbo zdravljenja s sertralinom krajše od 14 dni.
In controlled studies in normal volunteers, sertraline did not cause sedation and did not interfere with psychomotor performance.
V kontroliranih študijah pri zdravih prostovoljcih sertralin ni povzročil sedacije in ni vplival na psihomotorično zmogljivost.
“Combined data from the 3 studies of PTSD in the general population found a lower response rate in males compared to females.
„Združeni podatki iz treh študij o PTSM pri splošni populacij kažejo na nižji delež odziva pri moških v primerjavi z ženskami.
Use in children and adolescents under 18 years of age Sertraline should not be used in the treatment of children and adolescents under the age of 18 years, except for patients with obsessive compulsive disorder aged 6-17 years old.
Uporaba pri otrocih in mladostnikih, mlajših od 18 let Sertralina ne smete uporabljati za zdravljenje otrok in mladostnikov, mlajših od 18 let, razen za zdravljenje bolnikov z obsesivno-kompulzivno motnjo, starih od 6 do 17 let.
The data submitted to support the additional indication anxiety treatment indication proposed by the MAH consisted of various studies showing that the sertraline groups consistently had a greater reduction in the Ham-D Factor for anxiety and somatisation than the placebo group.
Podatke, predložene v podporo dodatni indikaciji zdravljenja anksioznosti, ki jo je predlagal imetnik dovoljenja za promet z zdravilom, so sestavljale različne študije, ki kažejo, da je imela skupina, zdravljena s sertralinom, v primerjavi s tisto, ki je prejemala placebo, dosledno večje zmanjšanje faktorja Ham-D za anksioznost in somatizacijo.
The most common side effects in children and adolescents were headache, insomnia, diarrhoea and feeling sick.
Najpogostejši neželeni učinki pri otrocih in mladostnikih so bili glavobol, nespečnost, driska in slabost v želodcu.
Concomitant intake of pimozide is contraindicated (see section 4.5).
Kontraindicirana je tudi sočasna uporaba s pimozidom (glejte poglavje 4.5).
Signs and symptoms of hyponatraemia include headache, difficulty concentrating, memory impairment, confusion, weakness and unsteadiness which may lead to falls.
Med znaki in simptomi hiponatriemije so glavobol, težave s koncentracijo, poslabšanje spomina, zmedenost, šibkost in negotovost pri gibanju, ki lahko povzroči padce.
Do not mix sertraline oral concentrate with anything other than the liquids listed.
Koncentrata za peroralno raztopino sertralina ne mešajte z ničimer drugim kot z naštetimi tekočinami.
In total, 13 short term RCTs were carried out in support of the MDD indication, in addition to one randomised withdrawal study and several other long-term studies.
V podporo indikaciji HDM je bilo izvedenih skupno 13 kratkoročnih, randomiziranih kliničnih preskušanj, poleg ene randomizirane ukinitvene ter več drugih dolgoročnih študij.
Section 4.1 - Indications: Obsessive Compulsive Disorder (In paediatric patients)
Poglavje 4.1 - Indikacije: Obsesivno kompulzivna motnja (pri pediatričnih bolnikih)
Since the bioavailability of sertraline capsules is increased in the presence of food, it is recommended that sertraline capsules be administered with meals.
Biološka uporabnost sertralina v kapsulah se v prisotnosti hrane zveča, zato je priporočljivo, da bolniki kapsule sertralina vzamejo ob obrokih.
In some Member States, OCD is also indicated in children and adolescents (aged 6-17).
V nekaterih državah članicah je indiciran tudi za zdravljenje OKM pri otrocih in mladostnikih (starih od 6 do 17 let).
Combined data from the 3 studies of PTSD in the general population found a lower response rate in males compared to females.
Združeni podatki 3 študij PTSD v splošni populaciji so pri moških pokazali manjši delež odziva kot pri ženskah.
• Medicines to treat excessive stomach acid and ulcers (cimetidine).
• Zdravila za zdravljenje čezmerne želodčne kisline in razjed (cimetidin)
Panic disorder, Social anxiety disorder and Post Traumatic Stress Disorder: For panic disorder, social anxiety disorder and post traumatic stress disorder, treatment should be started at (1.25 ml) 25 mg/day, and increased to (2.5 ml) 50 mg/day after one week.
Panična motnja, socialna anksiozna motnja in posttravmatska stresna motnja (PTSM): Pri panični motnji, posttravmatski stresni motnji ter pri socialni fobiji je začetni odmerek (1,25 ml) 25 mg enkrat na dan, ki ga bo zdravnik po enem tednu povišal na (2,5 ml) 50 mg enkrat na dan.
At clinical doses, sertraline blocks the uptake of serotonin into human platelets.
V kliničnih odmerkih sertralin zavre privzem serotonina v človeške trombocite.
• Post traumatic stress disorder (PTSD) (in adults).
• Posttravmatske stresne motnje (PTSM) (pri odraslih).
• Obsessive compulsive disorder (OCD) (in adults and children and adolescents aged 6-17 years old).
• Obsesivno kompulzivne motnje (OKM) (pri odraslih in mladostnikih starih 6-17 let).
Aminotransferarase Increased*, Aspartate Aminotransferase Increased*, Semen Abnormal
zvišanje alaninaminotransferaze*, zvišanje aspartataminotransferaze*.
Elderly patients may be at greater risk of developing hyponatraemia with SSRIs and SNRIs.
Starejši bolniki imajo med uporabo SSRI in SNRI morda večje tveganje za pojav hiponatriemije.
Section 4.1 - Indications: Social Anxiety Disorder
Poglavje 4.1 - Indikacije: Socialna anksiozna motnja
Reproductive System and Breast Disorders** Ejaculation
Motnje reprodukcije in dojk**
“Sertraline is indicated for the treatment of obsessive compulsive disorder (OCD) in adults”,
„Sertralin je indiciran za zdravljenje obsesivno kompulzivne motnje (OKM) pri odraslih“,
Your doctor will advise you on how long to take this medication for.
Zdravnik vam bo svetoval kako dolgo jemati zdravilo Zoloft.
• If you are having electro-convulsive therapy (ECT).
• Ali vas zdravijo z elektrokonvulzivno terapijo (EKT)?
Sertraline dosing does not have to be adjusted based on the degree of renal impairment.
Odmerjanja sertralina ni potrebno prilagoditi stopnji ledvične okvare.
Vision Abnormal
nenormalen vid
Possible Side Effects).
Možni neželeni učinki).
Pfizer Hellas A.E., 243 Messoghion Ave., 154 51 Ν. Psychiko, Athens Greece
Pfizer Hellas A.E., 243 Messoghion Ave., 154 51 Ν. Psychiko, Athens Grčija
“Continued treatment in panic disorder and OCD should be evaluated regularly, as relapse prevention has not been shown for these disorders”.
„Nadaljevanje zdravljenja pri panični motnji in obsesivno kompulzivni motnji (OKM) je treba redno ocenjevati, saj pri teh motnjah preprečevanje ponovitev (recidivov) bolezni ni bilo dokazano.“
In addition, co-administration of phenytoin may cause a reduction of sertraline plasma levels.
Poleg tega lahko sočasno jemanje fenitoina povzroči znižanje plazemske koncentracije sertralina.
Signs and symptoms associated with more severe and/or acute cases have included hallucination, syncope, seizure, coma, respiratory arrest, and death.
Med znaki in simptomi, ki so spremljali hujše in/ali akutne primere, so halucinacije, sinkopa, konvulzije, koma, zastoj dihanja in smrt.
The antibiotic linezolid is a weak reversible and non-selective MAOI and should not be given to patients treated with sertraline (see section 4.3).
Reverzibilni neselektivni zaviralci MAO (linezolid) Antibiotik linezolid je šibek reverzibilen, neselektiven zaviralec MAO, zato ga ne smejo dobiti bolniki, ki prejemajo sertralin (glejte poglavje 4.3).
Generally these symptoms are mild to moderate; however, in some patients they may be severe in intensity.
Na splošno so ti simptomi blagi do zmerni, pri nekaterih bolnikih pa so lahko tudi zelo izraziti.
It also contains glycerol which at high doses can cause headache, abdominal pain and diarrhea.
Vsebuje tudi glicerol, ki lahko v velikih odmerkih povzroči glavobol, bolečine v trebuhu in drisko.
Cases of serum sodium levels lower than 110 mmol/l have been reported.
Opisani so primeri koncentracije natrija v serumu pod 110 mmol/l.
• Panic disorder (in adults).
• Panične motnje (pri odraslih).
Other serotonergic drugs e.g. tryptophan, fenfluramine and 5-HT agonists Co-administration of sertraline with other drugs which enhance the effects of serotonergic neurotransmission such as tryptophan or fenfluramine or 5-HT agonists, or the herbal medicine, St John's Wort (hypericum perforatum), should be undertaken with caution and avoided whenever possible due to the potential for a pharmacodynamic interaction.
Druga serotoninergična zdravila kot npr. triptofan, fenfluramin in agonisti 5-HT Pri sočasni uporabi sertralina z drugimi zdravili, ki stopnjujejo učinke serotoninergičnega živčnega prenosa kot je npr. triptofan, fenfluramin, agonisti 5-HT ali zdravil rastlinskega izvora, ki vsebujejo šentjanževko (Hypericum perforatum), je potrebna previdnost; če je le mogoče, se je uporabi zaradi možnih farmakodinamičnih interakcij treba izogniti.
After one week, the dose should be increased to 50 mg once daily.
Po enem tednu je treba odmerek zvečati na 50 mg enkrat na dan.
Withdrawal reactions when treatment is stopped are common, particularly if the treatment is stopped suddenly (see section 4 Possible side effects).
Odtegnitvena reakcija ob koncu zdravljenja je mogoča, še posebej če je zdravljenje prekinjeno naenkrat (glej točko 4.
Comments were also made to the remaining sections of the SPC, and for all sections, the labelling and the package leaflet were revised accordingly.
Prav tako so bile podane pripombe za druga poglavja povzetka glavnih značilnosti zdravila ter ustrezno popravljena tudi vsa poglavja označevanja in navodila za uporabo.
A meta-analysis of placebo-controlled clinical trials of antidepressant drugs in adult patients with psychiatric disorders showed an increased risk of suicidal behaviour with antidepressants compared to placebo in patients less than 25 years old.
Metaanaliza s placebom nadzorovanih kliničnih preskušanj antidepresivov pri odraslih bolnikih s psihiatričnimi motnjami je pokazala, da pri bolnikih, mlajših od 25 let, pri uporabi antidepresivov obstaja večje tveganje za pojav samomorilnega vedenja kot pri uporabi placeba.
Nevertheless, it is possible that your doctor decides to prescribe Zoloft to a patient under 18 if it is in the patient's interest.
Kljub temu lahko vaš zdravnik, če se odloči, da je to najbolje za bolnika, predpiše zdravilo Zoloft za bolnike, mlajše od 18 let.