natgillin/translations-raw huggingface dataset:
Among patients with the highest number of blood eosinophils before treatment, the number of severe flareups per year was 0.66 in patients treated with Fasenra (given every 4 weeks for the first 3 doses and every 8 weeks afterwards), compared with 1.14 in patients given placebo (a dummy treatment).
Pri bolnikih z najvišjo koncentracijo eozinofilcev v krvi pred zdravljenjem je bilo število hudih zagonov bolezni na leto v skupini bolnikov, zdravljenih z zdravilom Fasenra (pri čemer so prve tri odmerke prejeli v razmiku štirih tednov, naslednje odmerke pa vsakih osem tednov), 0,66, pri bolnikih, ki so prejemali placebo (zdravilo brez učinkovine), pa 1,14.
The most common side effects with Fasenra (which may affect up to 1 in 10 people) include headache and pharyngitis (sore throat).
Najpogostejša neželena učinka zdravila Fasenra (ki se lahko pojavita pri največ 1 bolniku od 10) sta glavobol in faringitis (vnetje žrela).
If agreed with the treating doctor, patients already using Fasenra and with no history of severe allergic reactions, or their carers, can inject Fasenra themselves after proper training, including on how to watch out for signs and symptoms of allergic reactions.
Z dovoljenjem lečečega zdravnika lahko bolniki, ki že uporabljajo zdravilo Fasenra in niso nikoli imeli resnih alergijskih reakcij, ali njihovi negovalci po opravljenem ustreznem usposabljanju, ki je vključevalo tudi napotke za spremljanje znakov in simptomov alergijskih reakcij, sami injicirajo zdravilo Fasenra.
It can only be obtained with a prescription and treatment should be started by doctors with experience in the diagnosis and treatment of severe asthma.
Predpisovanje in izdaja zdravila je le na recept, zdravljenje pa mora uvesti zdravnik, ki ima izkušnje z diagnosticiranjem in zdravljenjem hude astme.
It is used as an additional treatment in adults with severe asthma that is not adequately controlled by a combination of high-dose inhaled corticosteroids plus medicines called long-acting beta-agonists.
Uporablja se kot dodatno zdravljenje pri odraslih s hudo astmo, ki ni ustrezno urejena s kombinacijo velikih odmerkov inhalacijskih kortikosteroidov in zdravil, imenovanih dolgodelujoči agonisti beta.
The active substance in Fasenra, benralizumab, is a monoclonal antibody (a type of protein) designed to attach to receptors (targets) called interleukin-5 receptors on the surface of eosinophils.
Učinkovina v zdravilu Fasenra, benralizumab, je monoklonsko protitelo (vrsta beljakovine), zasnovano za vezavo na receptorje (prijemališča), imenovane receptorji interlevkina-5, na površini eozinofilcev.
Fasenra activates the immune system (the body's natural defences) to kill the eosinophils in the blood and lungs.
interlevkina-5 aktivira imunski sistem (naravno obrambo telesa), da uniči eozinofilce v krvi in pljučih.
Fasenra has been shown to be more effective than placebo at reducing the number of asthma flare-ups and the need for corticosteroid treatment.
Zdravilo Fasenra se je pri zmanjševanju števila zagonov astme in potrebe po zdravljenju s kortikosteroidi izkazalo za učinkovitejše od placeba.
For the full list of side effects and restrictions of Fasenra, see the package leaflet.
Za celoten seznam neželenih učinkov in omejitev pri uporabi zdravila Fasenra glejte navodilo za uporabo.
Fasenra is an asthma medicine used to treat adults with a particular type of asthma called eosinophilic asthma.
Zdravilo Fasenra je zdravilo za astmo, ki se uporablja za zdravljenje odraslih s posebno vrsto astme, imenovano eozinofilna astma.
In eosinophilic asthma, symptoms are associated with having too many of a type of white blood cell called eosinophils in the blood and in phlegm in the lungs.
Simptomi pri eozinofilni astmi so povezani s prevelikim številom določene vrste belih krvnih celic, imenovanih eozinofilci, v krvi in pljučni sluzi.
Fasenra is available as a solution for injection in pre-filled syringes and pre-filled pens.
Zdravilo Fasenra je na voljo v obliki raztopine za injiciranje v napolnjeni injekcijski brizgi ali peresniku.
How is Fasenra used?
Kako se zdravilo Fasenra uporablja?
How does Fasenra work?
Kako zdravilo Fasenra deluje?
Fasenra contains the active substance benralizumab.
Vsebuje učinkovino benralizumab.
Fasenra was shown to reduce the number of exacerbations (flare-ups) of asthma during treatment in 2 main studies involving a total of 2,511 patients with eosinophilic asthma that was not adequately controlled by a combination of high-dose inhaled corticosteroids and long-acting beta-agonists.
V dveh glavnih študijah, v kateri je bilo skupno vključenih 2 511 bolnikov z eozinofilno astmo, ki ni bila ustrezno nadzorovana s kombinacijo velikih odmerkov inhalacijskih kortikosteroidov in dolgodelujočih agonistov beta, so dokazali, da zdravljenje z zdravilom Fasenra zmanjša število poslabšanj (zagonov) astme.
When should I seek advice or help?
Kdaj naj poiščem nasvet ali pomoč?
What can I do to help relieve my symptoms?
Kaj lahko storim, za olajšanje simptomov?
Why do you get these symptoms?
Zakaj se pojavijo ti simptomi?
Do not use any other liquids.
Ne uporabljajte nobenih drugih tekočin.
This could be a sign of a serious condition with your heart.
To je lahko znak resnega stanja povezanega z vašim srcem.
If you forget to take a dose, take it as soon as you remember it, on the same day.
Če pozabite vzeti odmerek, ga vzemite takoj, ko se spomnite, v istem dnevu.
Date of first authorisation: 26 August 2013 Date of latest renewal: 25 June 2018
Datum prve odobritve: 26. avgust 2013 Datum zadnjega podaljšanja: 25. junij 2018
Children and adolescents This medicine should not be used by children and adolescents under 18 years of age.
Tega zdravila ne smejo jemati otroci in mladostniki, mlajši od 18 let.
Always stir the mixture just before drinking it.
Mešanico vedno premešajte, tik preden jo popijete.
• Avoid fizzy drinks, coffee, chocolate and alcohol.
• izogibajte se gaziranim pijačam, kavi, čokoladi in alkoholu;
• Eat slowly and eat smaller portions.
• jejte počasi in uživajte manjše obroke;
This is because this medicine can affect the way some medicines work and some medicines can have an effect on it.
To zdravilo namreč lahko vpliva na delovanje nekaterih zdravil in nekatera zdravila lahko vplivajo na to zdravilo.
• Stir until the tablet breaks up (the mixture will not be clear) then drink the mixture straight away or within 30 minutes.
• Mešajte, dokler se tableta ne razpusti (mešanica ne bo bistra), nato mešanico popijte takoj ali v 30 minutah.
In addition, the safety profile is similar for different formulations, treatment indications, age groups and patient populations.
Poleg tega so varnostne značilnosti podobne za različne farmacevtske oblike, indikacije zdravljenja, starostne skupine in populacije bolnikov.
FURTHER HELPFUL INFORMATION
DODATNE KORISTNE INFORMACIJE
• You are due to have a specific blood test (Chromogranin A).
• ste naročeni na specifično preiskavo krvi (kromogranin A).
General Patients should be instructed to consult a doctor if:
Splošno Bolnikom je treba naročiti, naj se posvetujejo z zdravnikom:
• Eat healthier food and try to avoid spicy and fatty foods and large meals late before bedtime.
• Uživajte bolj zdravo hrano in se izogibajte začinjeni ter mastni hrani in velikim obrokom pred spanjem;
The duration of treatment is up to 2 weeks.
Zdravljenje traja do 2 tedna.
The majority of these rated the importance of this change to be Important to Extremely Important in performing their activities of daily living (79 - 86% at week 2).
Večina teh bolnikov je ocenila spremembo kot pomembno do izredno pomembno za opravljanje vsakodnevnih dejavnosti (79 - 86 % 2. teden).
If any of the above apply to you (or you are not sure), talk to your doctor straight away.
Če kaj od naštetega velja za vas (ali če niste prepričani), se takoj posvetujte z zdravnikom.
• Stop smoking.
• prenehajte kaditi.
• The treatment length is up to 14 days.
• Zdravljenje traja do 14 dni.
Poor metabolisers
Slabi metabolizatorji
Treatment should be symptomatic and general supportive measures should be utilised.
Zdravljenje mora biti simptomatsko, z uporabo splošnih podpornih ukrepov.
The clinical importance and the mechanisms behind these reported interactions are not always known.
Klinični pomen in mehanizmi teh opisanih medsebojnih delovanj niso vedno znani.
Less than 1% of the parent compound is found in urine.
V urinu se pojavi manj kot 1 % matičnega zdravila.
• Seeing, feeling or hearing things that are not there (hallucinations)
• videnje, občutenje ali slišanje stvari, ki jih ni (halucinacije)
Tell your doctor immediately before or after taking this medicine, if you notice any of the following symptoms, which could be a sign of another, more serious, disease.
Zdravniku morate takoj, pred ali po jemanju tega zdravila povedati, če opazite katerega od naslednjih simptomov, ki so lahko znak druge, resnejše bolezni:
If you have very low levels of magnesium, you may also have low levels of calcium and/or potassium in your blood.
Če imate zelo nizko koncentracijo magnezija, imate lahko v krvi tudi nizko koncentracijo kalcija in/ali kalija.
The reactions are classified according to MedDRA frequency convention: very common (≥ 1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); not known (cannot be estimated from the available data).
Učinki so razvrščeni glede na dogovor o pogostnosti MedDRA: zelo pogosti (> 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1.000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000), zelo redki (< 1/10.000), neznana (ni mogoče oceniti iz razpoložljivih podatkov).
There is insufficient information on the effects of esomeprazole in newborns/infants.
O učinkih esomeprazola pri novorojenčkih in dojenčkih ni dovolj informacij.
Hypersensitivity to the active substance, substituted benzimidazoles or to any of the excipients listed in section 6.1.
Preobčutljivost na učinkovino, substituirane benzimidazole ali katerokoli pomožno snov, navedeno v poglavju 6.1.
Medicinal products with pH dependent absorption
Zdravila, katerih absorpcija je odvisna od pH
Adverse reactions not observed in clinical studies, but seen in animals at exposure levels similar to clinical exposure levels and with possible relevance to clinical use were as follows:
Neželeni učinki, ki jih v kliničnih študijah niso zabeležili, opazili pa so jih pri živalih ob izpostavljenostih, podobnih kliničnim izpostavljenostim, in bi lahko bili pomembni za klinično uporabo, so:
Heartburn can be a result of eating too much, eating high fat food, eating too quickly and drinking lots of alcohol.
Zgaga je lahko posledica prenajedanja, uživanja hrane z veliko vsebnostjo maščob, prehitrega zaužitja hrane in pitja velike količine alkohola.
Capsules
kapsule
Pfizer Consumer Manufacturing Italy S.r.l., Via Nettunense, 90, 04011, Aprilia (LT), Italy.
Pfizer Consumer Manufacturing Italy S.r.l., Via Nettunense, 90, 04011 Aprilia (LT), Italija
Patients should not take Nexium Control as a long term preventive medicinal product.
Bolniki zdravila Nexium Control ne smejo jemati kot zdravila za dolgoročno preventivo.
Due to limited experience in patients with severe renal insufficiency, such patients should be treated with caution (see section 5.2).
Izkušenj pri bolnikih s hudo insuficienco ledvic je malo, zato je treba takšne bolnike zdraviti previdno (glejte poglavje 5.2).
A dose adjustment of esomeprazole is not regularly required in either of these situations.
V nobeni od teh okoliščin odmerka esomeprazola praviloma ni treba prilagoditi.
• Medicines that are used to thin your blood, such as warfarin.
• zdravila, ki se uporabljajo za redčenje krvi, na primer varfarin.
What are the symptoms of heartburn?
Kakšni so simptomi zgage?
You should specifically tell your doctor or pharmacist if you are taking clopidogrel (used to prevent blood clots).
Zdravniku ali farmacevtu morate posebej povedati, če jemljete klopidogrel (zdravilo, ki se uporablja za preprečevanje nastajanja krvnih strdkov).
• You can take your capsule at any time of the day either with food or on an empty stomach.
• Kapsulo lahko vzamete kadarkoli v teku dneva, s hrano ali na prazen želodec.
A reinforced monitoring of tacrolimus concentrations as well as renal function (creatinine clearance) should be performed, and the dose of tacrolimus adjusted if needed.
Intenzivneje je treba nadzirati koncentracijo takrolimusa in delovanje ledvic (očistek kreatinina), odmerek takrolimusa pa prilagoditi, če je treba.
Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicinal product.
Bolniki z redko dedno intoleranco za fruktozo, malabsorbcijo glukoze/galaktoze ali pomanjkanjem saharoza-izomaltaze ne smejo jemati tega zdravila.
• Increased liver enzymes shown in blood tests that check how the liver is working.
• zvišane vrednosti jetrnih encimov, ki jih pokažejo izvidi krvnih preiskav, s katerimi preverjamo delovanje jeter
You should not use this medicine during breast-feeding.
Tega zdravila ne uporabljajte med dojenjem.
They work by reducing the amount of acid that your stomach produces.
Delujejo tako, da zmanjšajo količino kisline, ki nastaja v želodcu.
• You lose a lot of weight for no reason.
• hujšanje brez razloga,
• Low levels of magnesium in the blood.
• nizka koncentracija magnezija v krvi.
A moderate amount of data on pregnant women (between 300-1,000 pregnancy outcomes) indicate no malformative or feto/ neonatal toxicity of esomeprazole.
Zmeren obseg podatkov o nosečnicah (od 300 do 1.000 izidov nosečnosti) ne kaže, da bi esomeprazol povzročal malformacije, fetotoksične učinke ali toksične učinke na novorojenčka.
• You can take your tablet at any time of the day either with food or on an empty stomach.
• Tableto lahko vzamete kadarkoli v teku dneva, s hrano ali na prazen želodec.
Approximately 2.9±1.5% of the population lack a functional CYP2C19 enzyme and are called poor metabolisers.
Približno 2,9 ± 1,5 % populacije nima funkcionalnega CYP2C19 in jih imenujemo slabi metabolizatorji.
You may also notice that when you lie down, that your heartburn gets worse.
Morda boste opazili, da se zgaga poslabša, kadar se uležete.
• You have problems or pain when swallowing.
• težave ali bolečine pri požiranju,
If you have persistent or longstanding, frequently recurring symptoms even after treatment with this medicine, you should contact your doctor.
Če imate trdovratne ali dolgotrajne, pogosto ponavljajoče se simptome tudi še po zdravljenju s tem zdravilom, se morate posvetovati z zdravnikom.
However, the maximum levels of inhibition of (ADP induced) platelet aggregation in these subjects were the same in both groups.
Največja raven zavrtja (z ADP inducirane) agregacije trombocitov pa je bila pri preiskovancih v obeh skupinah enaka.
• The recommended dose is one tablet a day.
• Priporočeni odmerek je ena tableta na dan.
Patients over 55 years taking any non-prescription indigestion or heartburn remedy on a daily basis should inform their pharmacist or doctor.
Bolniki, starejši od 55 let, ki vsak dan jemljejo brez recepta dostopna zdravila proti želodčnim težavam ali zgagi, morajo o tem obvestiti farmacevta ali zdravnika.
This increase is dose-dependent and results in a more than dose proportional increase in AUC after repeated administration.
Povečanje je odvisno od odmerka in po večkratni uporabi povzroči več kot odmerku sorazmerno povečanje AUC.
No other liquids should be used as the enteric coating may be dissolved.
Drugih tekočin se ne sme uporabljati, ker se lahko gastrorezistentna obloga raztopi.
Symptoms associated with acid reflux (such as heartburn and acid regurgitation) were evaluated retrospectively over a 24 hour period.
Simptome, povezane z refluksom želodčne kisline (kot sta zgaga in regurgitacija kisline), so ocenjevali retrospektivno v 24-urnem obdobju.
To avoid this interference, Nexium Control treatment should be stopped for at least 5 days before CgA measurements (see section 5.1).
Da bi to preprečili, je treba vsaj pet dni pred meritvami CgA prekiniti zdravljenje z zdravilom Nexium Control (glejte poglavje 5.1).
Do not use if you are allergic to esomeprazole or any of the other ingredients of this medicine.
Ne jemljite zdravila, če ste alergični na esomeprazol ali katerokoli drugo sestavino tega zdravila.
• You have severe or persistent diarrhoea; esomeprazole has been associated with a small increased risk of infectious diarrhoea.
• huda ali trdovratna driska; esomeprazol je povezan z nekoliko večjim tveganjem za infekcijsko drisko,
Esomeprazole has minor influence on the ability to drive or use machines.
Esomeprazol ima manjši vpliv na sposobnost vožnje in upravljanja strojev.
It belongs to a group of medicines called ‘proton pump inhibitors'.
Spada v skupino zdravil, ki jih imenujemo "zaviralci protonske črpalke".
If you notice any of the following serious side effects, stop taking Nexium Control and contact a doctor immediately:
Če opazite katerega od naslednjih resnih neželenih učinkov, nehajte jemati zdravilo Nexium Control in se takoj posvetujte z zdravnikom:
Due to the similar pharmacodynamic effects and pharmacokinetic properties of omeprazole and esomeprazole, concomitant administration with esomeprazole and atazanavir is not recommended and concomitant administration with esomeprazole and nelfinavir is contraindicated (see section 4.3 and 4.4).
Zaradi podobnih farmakodinamičnih učinkov in farmakokinetičnih značilnosti omeprazola in esomeprazola sočasna uporaba esomeprazola in atazanavirja ni priporočljiva, sočasna uporaba esomeprazola in nelfinavirja pa je kontraindicirana (glejte poglavji 4.3 in 4.4).
• The active substance is esomeprazole.
• Učinkovina je esomeprazol.
If lesions occur, especially in sun-exposed areas of the skin, and if accompanied by arthralgia, the patient should seek medical help promptly and the health care professional should consider stopping Nexium Control.
Če se pojavijo lezije, zlasti na koži, ki je izpostavljena soncu, in sočasna artralgija, mora bolnik takoj poiskati zdravniško pomoč, zdravstveni delavec pa mora razmisliti o prekinitvi zdravljenja z zdravilom Nexium Control.
However, patients with severe liver impairment should be advised by a doctor before taking Nexium Control (see sections 4.4 and 5.2).
Bolnikom s hudo okvaro jeter pa je treba naročiti, naj se pred jemanjem zdravila Nexium Control posvetujejo z zdravnikom (glejte poglavji 4.4 in 5.2).
- If you are allergic to medicines containing other proton pump inhibitors (e.g. pantoprazole,
- Če ste alergični na zdravila, ki vsebujejo druge zaviralce protonske črpalke (npr. pantoprazol,
Almost 80% of an oral dose of esomeprazole is excreted as metabolites in the urine, the remainder in the faeces.
Skoraj 80 % peroralnega odmerka esomeprazola se izloči v obliki presnovkov v urinu, preostanek pa v blatu.
The median time to first resolution of night-time heartburn was 1 day, statistically significant compared to placebo in one study (p=0.048) and approaching significance in the other (p=0.069).
Mediana časa do prvega prenehanja nočne zgage je bila en dan, kar je bilo v eni študiji statistično pomembno v primerjavi s placebom (p = 0,048) in skoraj statistično pomembno v drugi študiji (p = 0,069).
• The recommended dose is one capsule a day.
• Priporočeni odmerek je ena kapsula na dan.
• Put the tablet in a glass of still (non-fizzy) water.
• Tableto dajte v kozarec negazirane vode (vode brez mehurčkov).
Metabolism and nutrition disorders peripheral oedema hyponatraemia hypomagnesaemia; severe hypomagnesaemia can correlate with hypocalcaemia; hypomagnesaemia may also result in hypokalaemia
Presnovne in prehranske motnje periferni edemi hiponatriemija hipomagneziemija, huda hipomagneziemija je lahko povezana s hipokalciemijo; hipomagneziemija lahko povzroči hipokaliemijo
Esomeprazole 20 mg should not be exceeded.
Odmerek esomeprazola ne sme preseči 20 mg.
+K+-ATPase
+K+-ATPazo (kislinsko črpalko).
This could be ‘Stevens-Johnson syndrome' or ‘toxic epidermal necrolysis', seen very rarely.
To je lahko t. i. Stevens-Johnsonov sindrom ali toksična epidermalna nekroliza; pojavi se zelo redko.
Talk to your pharmacist or doctor if:
Posvetujte se z zdravnikom ali farmacevtom, če:
Absorption of esomeprazole is rapid, with peak plasma levels occurring approximately 1-2 hours after dose.
Absorpcija esomeprazola je hitra, najvišjo koncentracijo v plazmi pa doseže približno 1 do 2 uri po odmerku.
Corresponding proportions for esomeprazole 40 mg were 97%, 92% and 56%.
Po 40 mg esomeprazola so bili ti deleži 97 %, 92 % in 56 %.
Combination with other medicinal products
Kombinacija z drugimi zdravili
• To make sure that you have drunk all of the medicine, rinse the glass very well with half a glass of water and drink it.
• Da boste popili zares vse zdravilo, kozarec nato zelo dobro splaknite s pol kozarca vode in to vodo popijte.
Nexium Control is not meant to bring immediate relief.
Zdravilo Nexium Control ni namenjeno takojšnjemu olajšanju težav.
You may take this medicine with antacids (e.g. magaldrate, alginic acid, sodium bicarbonate, aluminium hydroxide, magnesium carbonate or combinations of these) if needed.
To zdravilo lahko jemljete z antacidi (na primer z magaldratom, alginsko kislino, natrijevim bikarbonatom, aluminijevim hidroksidom, magnezijevim karbonatom ali njihovimi kombinacijami), če je to potrebno.
The apparent volume of distribution at steady state in healthy subjects is approximately 0.22 l/kg body weight.
Navidezni volumen porazdelitve v stanju dinamičnega ravnovesja je pri zdravih preiskovancih približno 0,22 l/kg telesne mase.
Tell your doctor or pharmacist if you are taking any of the following medicines:
Zdravniku ali farmacevtu morate povedati, če jemljete katero od naslednjih zdravil:
Esomeprazole should not be used during breast-feeding.
Esomeprazola se med obdobjem dojenja ne sme uporabljati.
• You have ever had a skin reaction after treatment with a medicine similar to Nexium Control that reduces stomach acid.
• ste že kdaj imeli kožno reakcijo po zdravljenju z zdravilom, podobnim zdravilu Nexium
Patients should consult their doctor before taking this medicinal product if they are due to have an endoscopy or urea breath test.
Pred jemanjem tega zdravila naj se bolniki posvetujejo z zdravnikom, če imajo predvideno endoskopijo ali dihalni test s sečnino.
Esomeprazole is 97% plasma protein bound.
Esomeprazol se v 97 % veže na beljakovine v plazmi.
Esomeprazole is completely metabolised by the cytochrome P450 system (CYP).
Esomeprazol se povsem presnovi s sistemom citokroma P450 (CYP).
• Do not take more than this recommended dose of one tablet (20 mg) a day, even if you don't feel an improvement immediately.
• Ne vzemite večjega odmerka od priporočenega, ki je ena tableta (20 mg) na dan, tudi če ne čutite takoj izboljšanja.
Gastro-resistant tablet.
Gastrorezistentna tableta.
Esomeprazole is the S-isomer of omeprazole and reduces gastric acid secretion through a specific targeted mechanism of action.
Esomeprazol je S-izomer omeprazola in zmanjša izločanje želodčne kisline prek specifičnega mehanizma delovanja.
It is important not to damage the pellets.
Pomembno je, da se zrnca ne poškodujejo.
Pharmacotherapeutic group: Drugs for acid related disorders, proton pump inhibitors, ATC code: A02BC05.
Farmakoterapevtska skupina: zdravila za kislinsko pogojene bolezni, zaviralci protonske črpalke, oznaka ATC: A02BC05.
The slightly prolonged QTc interval observed after administration of cisapride alone, was not further prolonged when cisapride was given in combination with esomeprazole.
Rahlo podaljšanje intervala QTc, opaženo po uporabi samega cisaprida, se med sočasno uporabo cisaprida in esomeprazola ni dodatno povečalo.
• You get a rash on your skin, especially in areas exposed to the sun tell your doctor as soon as you can, as you may need to stop your treatment with Nexium Control.
• če se pojavi kožni izpuščaj, zlasti na koži, ki je izpostavljena soncu, čim prej obvestite zdravnika, saj boste morda morali prekiniti zdravljenje z zdravilom Nexium Control.
Your doctor may need to monitor you when you start or stop taking Nexium Control.
Zdravnik vas bo morda moral spremljati, ko boste začeli ali nehali jemati zdravilo Nexium Control.