natgillin/translations-raw huggingface dataset:
Sevelamer does not contain calcium and decreases the incidence of hypercalcaemic episodes as compared to patients using calcium based phosphate binders alone.
Sevelamer ne vsebuje kalcija in zmanjšuje pojavnost epizod hiperkalcemije v primerjavi z bolniki, ki uporabljajo samo vezalce fosfata na podlagi kalcija.
These figures were 23% and 15% in the subgroup of patients on hemodialysis and peritoneal dialysis, respectively.
Ta delež je bil v podskupini bolnikov na hemodializi 23 % in v podskupini bolnikov na peritonealni dializi 15 %.
Consequently, sevelamer carbonate should not be taken simultaneously with ciprofloxacin.
Zato se sevelamerijevega karbonata ne sme jemati sočasno s ciprofloksacinom.
If you have missed one dose, this dose should be omitted and the next dose should be taken at the usual time with a meal.
Če pozabite vzeti odmerek, ga izpustite in naslednji odmerek vzemite kot običajno s hrano.
Sevelamer has no or negligible influence on the ability to drive and use machines.
Sevelamer nima vpliva ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja strojev.
The suspension should be ingested within 30 minutes after being prepared.
Suspenzijo je treba zaužiti v 30 minutah po pripravi.
What you need to know before you take Renvela 3.
Kaj morate vedeti, preden boste vzeli zdravilo Renvela 3.
Serum calcium levels should therefore be monitored at regular intervals and elemental calcium should be given as a supplement if required.
Zato je treba ravni kalcija v serumu redno nadzirati in po potrebi dodajati elementarni kalcij.
Patients receiving dialysis are subject to certain risks for infection specific to dialysis modality.
Bolniki na dializi so izpostavljeni nekaterim tveganjem za okužbe, ki so odvisne od načina dialize, ki jo prejemajo.
It is unknown whether sevelamer/metabolites are excreted in human milk.
Ni znano, ali se sevelamer/presnovki izločajo v mleko pri človeku.
Intestinal obstruction and ileus/subileus
Obstrukcija črevesja in ileus/subileus
The powder should not be heated (e.g. microwave).
Praška se ne sme segrevati (npr. mikrovalovna pečica).
It can be used in patients undergoing haemodialysis (using a blood filtration machine) or peritoneal dialysis (where fluid is pumped into the abdomen and an internal body membrane filters the blood);
Lahko se uporablja pri bolnikih na hemodializi (uporaba stroja za filtracijo krvi) ali na peritonealni dializi (tekočina se črpa v trebuh, notranja telesna membrana pa filtrira kri);
A total of 101 patients (6 to 18 years old with a BSA range of 0.8 m2 to 2.4 m2) were randomised in the study.
V študijo je bil v celoti randomiziran 101 bolnik (starost od 6 do 18 let in razpon telesne površine od 0,8 do 2,4 m2).
Additional treatments Due to either your kidney condition or your dialysis treatment you may:
Dodatno zdravljenje Zaradi težav z ledvicami ali zdravljenjem z dializo se lahko:
• paediatric patients with chronic (long-term) kidney disease above the age of 6 and above a certain height and weight (used to calculate body surface area by your physician).
• pediatričnih bolnikih s kronično (dolgotrajno) boleznijo ledvic, starejših od 6 let ter nad določeno telesno višino in telesno maso (ta dva podatka zdravnik uporabi za izračun telesne površine).
Contact your doctor who will decide on continuing the treatment or not.
Obrnite se na svojega zdravnika, ki bo presodil, ali naj zdravljenje nadaljujete ali ne.
It cannot be excluded that sevelamer carbonate can bind fat-soluble vitamins contained in ingested food.
Ni mogoče izključiti, da lahko sevelamerijev karbonat veže v maščobi topne vitamine v zaužiti hrani.
• Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
• preobčutljivost na učinkovino ali katero koli pomožno snov, navedeno v poglavju 6.1.
Sevelamer carbonate should only be given to pregnant women if clearly needed and after a careful risk/benefit analysis has been conducted for both the mother and the foetus.
Sevelamerijev karbonat naj nosečnice uporabljajo le, če ga nujno potrebujejo, in po skrbni presoji razmerja med koristmi in tveganjem za mater in plod.
Talk to your doctor who will decide if you can continue the treatment with Renvela.
Posvetujte se s svojim zdravnikom, ki bo presodil, ali lahko nadaljujete zdravljenje z zdravilom Renvela.
Adverse reactions that occurred during clinical trials or that were spontaneously reported from postmarketing experience are listed by frequency in the table below.
Neželeni učinki, ki so se pojavili med kliničnimi študijami in tisti, ki so bili spontano poročani med izkušnjami v obdobju trženja so po pogostnosti našteti v spodnji preglednici.
Fat-soluble vitamins and folate deficiency
V maščobi topni vitamini in pomanjkanje folatov
What Renvela is and what it is used for
Kaj je zdravilo Renvela in za kaj ga uporabljamo
(Instructions for presentation WITHOUT dosing spoon)
(Navodila za obliko BREZ odmerne žličke)
When administering any medicinal product where a reduction in the bioavailability could have a clinically significant effect on safety or efficacy, the medicinal product should be administered at least one hour before or three hours after sevelamer carbonate, or the physician should consider monitoring blood levels.
Pri dajanju katerih koli zdravil, pri katerih ima lahko zmanjšana biološka uporabnost klinično značilen vpliv na varnost ali učinkovitost, je treba zdravilo uporabiti vsaj eno uro pred ali tri ure po uporabi sevelamerijevega karbonata, ali pa mora zdravnik razmisliti o nadzoru ravni v krvi.
These protonated amines bind negatively charged ions such as dietary phosphate in the intestine.
Ti protonirani amini vežejo ione z negativnim nabojem kot so dietni fosfati v črevesju.
Patients taking anti-arrhythmic medicinal products for the control of arrhythmias and anti-seizure medicinal products for the control of seizure disorders were excluded from clinical trials.
Bolniki, ki jemljejo antiaritmična zdravila za nadzor aritmij in antiepileptična zdravila za nadzor epileptičnih napadov, so bili izključeni iz kliničnih preskušanj.
In a clinical trial of one year, no evidence of accumulation of sevelamer was seen.
V enoletnem kliničnem preskušanju niso opažali kopičenja sevelamerja.
Peritonitis is a known complication in patients receiving peritoneal dialysis and in a clinical trial with sevelamer hydrochloride, a greater number of peritonitis cases were reported in the sevelamer group than in the control group.
Peritonitis je znan zaplet pri bolnikih, ki prejemajo peritonealno dializo, in v kliničnih študijah s sevelamerijevim kloridom so poročali o več primerih peritonitisa v skupini, ki je prejemala sevelamer, kot v kontrolni skupini.
Renvela film-coated tablets are white tablets with Renvela 800 imprinted on one side.
Renvela filmsko obložene tablete so bele tablete z natisom Renvela 800 vtisnjenim na eni strani.
Triglycerides, HDL-cholesterol and albumin levels did not change following sevelamer treatment.
Ravni trigliceridov, HDL holesterola in albumina se po zdravljenju s sevelamerom niso spremenile.
Stopping Renvela would lead to important consequences such as calcification in the blood vessels.
Prenehanje jemanja zdravila Renvela bi imelo pomembne posledice, na primer kalcifikacije v žilah.
It is recommended that vitamin supplements be given if necessary.
Priporoča se redno jemanje vitaminskih nadomestkov.
Sevelamer carbonate is not indicated for the control of hyperparathyroidism.
Sevelamerijev karbonat ni indiciran za nadzorovanje hiperparatiroidizma.
Instead of water, the powder may be pre-mixed with a small amount of cold beverage (about 120 ml or half a glass) or food (about 100 grams) and consumed within 30 minutes.
Namesto z vodo, lahko prašek predhodno pomešate z majhno količino pijače (približno 120 ml ali pol kozarca) ali hrane (približno 100 gramov) in zaužijete v 30 minutah.
In rats and dogs, sevelamer reduced absorption of fat soluble vitamins D, E and K (coagulation factors), and folic acid.
Pri podganah in psih je sevelamer zmanjšal absorpcijo v maščobi topnih vitaminov D, E in K (koagulacijski faktorji) in folne kisline.
No new risks or safety signals were identified with the use of sevelamer carbonate during the study.
Med uporabo sevelamerijevega karbonata v študiji niso opazili novih tveganj ali varnostnih signalov.
If you consider stopping your Renvela treatment, contact your doctor or pharmacist first.
Če razmišljate o prenehanju jemanja zdravila Renvela, se najprej posvetujte z zdravnikom ali farmacevtom.
Sevelamer hydrochloride, which contains the same active moiety as sevelamer carbonate, is not absorbed from the gastrointestinal tract, as confirmed by an absorption study in healthy volunteers.
Sevelamerijev klorid, ki vsebuje enako učinkovino kot sevelamerijev karbonat, se ne absorbira iz prebavnega trakta, kar potrjuje študija absorpcije pri zdravih prostovoljcih.
Use the provided dosing spoon for each 0.4 g dose of Renvela powder.
Uporabite priloženo odmerno žličko za vsak 0,4 g odmerek praška zdravila Renvela.
In a 12 week study involving peritoneal dialysis patients however, similar iPTH reductions were seen compared with patients receiving calcium acetate.
Vendar pa so v 12-tedenski študiji, ki je zajemala bolnike na peritonealni dializi, opazili podobna znižanja iPTH v primerjavi z bolniki, ki so prejemali kalcijev acetat.
Initially, your doctor will check the levels of phosphorus in your blood every 2-4 weeks and may adjust the dose of Renvela when necessary to reach an adequate phosphate level.
Vaš zdravnik bo na začetku zdravljenja vsake 2 - 4 tedne preverjal ravni fosforja v vaši krvi in po potrebi prilagodil odmerek zdravila Renvela, če bo to treba zaradi doseganja ustrezne ravni fosfata.
Pharmacokinetic studies have not been carried out with sevelamer carbonate.
Farmakokinetičnih študij s sevelamerijevim karbonatom niso izvajali.
Patients taking sevelamer carbonate should adhere to their prescribed diets.
Bolniki, ki jemljejo sevelamerijev karbonat, morajo upoštevati predpisano dieto.
Because sevelamer binds bile acids, it may interfere with the absorption of fat soluble vitamins such as A, D, E and K.
Ker sevelamer veže žolčne kisline, lahko vpliva na absorpcijo v maščobi topnih vitaminov kot so A, D, E in K.
(Instructions for presentation with dosing spoon) Each carton contains 90 sachets and a dosing spoon to measure the 0.4 g dose of powder.
(Navodila za obliko z odmerno žličko) Vsaka škatla vsebuje 90 vrečic in odmerno žličko, s katero se odmeri 0,4 g praška.
• The effects of medicines such as ciclosporin, mycophenolate mofetil and tacrolimus (medicines used to suppress the immune system) may be reduced by Renvela.
• Učinke zdravil kot so ciklosporin, mofetilmikofenolat in takrolimus (zdravila, ki zavirajo odziv imunskega sistema), lahko zdravilo Renvela zmanjša.
What Renvela looks like and contents of the pack
Izgled zdravila Renvela in vsebina pakiranja
In an in vitro mammalian cytogenetic test with metabolic activation, sevelamer hydrochloride caused a statistically significant increase in the number of structural chromosome aberrations.
V in vitro citogenetskem testu pri sesalcih z aktivacijo presnove je sevelamerijev klorid povzročil statistično značilno povečanje števila strukturnih kromosomskih aberacij.
Taking your Renvela treatment is important to maintain an appropriate phosphate level in your blood.
Jemanje zdravila Renvela je pomembno za vzdrževanje ustrezne koncentracije fosfata v krvi.
Uncommon reports of difficulty swallowing the Renvela tablet have been reported.
Občasno so poročali o težavah s požiranjem tablet Renvela.
The highest dose in this study was 4.5 g/kg/day (human equivalent dose 2 times the maximum clinical trial dose of 13 g/day, based on a comparison of relative BSA).
Najvišji odmerek v tej študiji je bil 4,5 g/kg/dan (pri človeku primerljivo z odmerkom, dvakrat večjim od največjega odmerka v kliničnem preskušanju, ki je 13 g/dan, na osnovi relativne površine telesa).
Therefore this medicine is not recommended for use in children below the age of 6 years.
Zato uporaba tega zdravila pri otrocih, starih manj kot 6 let, ni priporočljiva.
180 (6 bottles of 30) film-coated tablets
180 (6 vsebnikov po 30) filmsko obloženih tablet
A decision on whether to continue/discontinue breast-feeding or to continue/discontinue therapy with sevelamer carbonate should be made taking into account the benefit of breast-feeding to the child and the benefit of sevelamer carbonate therapy to the woman.
Odločitev o nadaljevanju/prekinitvi dojenja ali nadaljevanju/prekinitvi zdravljenja s sevelamerijevim karbonatom je treba sprejeti ob upoštevanju dejavnikov prednosti dojenja za otroka in prednosti terapije s sevelamerijevim karbonatom za bolnico.
• Hypophosphataemia
• hipofosfatemija
- If you have further questions, ask your doctor or pharmacist.
• Če imate dodatna vprašanja, se posvetujte s svojim zdravnikom ali farmacevtom.
In patients undergoing peritoneal dialysis additional monitoring of fat-soluble vitamins and folic acid is recommended, since vitamin A, D, E and K levels were not measured in a clinical study in these patients.
Pri bolnikih, ki so na peritonealni dializi, se priporoča tudi nadziranje v maščobi topnih vitaminov in folne kisline, ker ravni vitaminov A, D, E in K v klinični študiji pri teh bolnikih niso merili.
The recommended starting dose of Renvela for children is based on their height and weight (used to calculate body surface area by your physician).
Priporočeni začetni odmerek zdravila Renvela za otroke temelji na njihovi telesni višini in telesni masi (ta dva podatka zdravnik uporabi za izračun telesne površine).
Constipation is a very common side effect (may affect more than 1 in 10 people).
Zaprtost je zelo pogosti neželeni učinek (pojavi se lahko pri več kot 1 od 10 oseb).
In CKD patients, the maximum average daily dose studied was 14.4 grams of sevelamer carbonate in a single daily dose.
Pri bolnikih s KBL je bil največji preučen povprečni dnevni odmerek 14,4 grama sevelamerijevega karbonata v obliki enega dnevnega odmerka.
The treatment response during the 2-week FDP was not affected by BSA, in contrast however, no treatment response was observed in paediatric patients with qualifying phosphorus levels <7.0 mg/dL.
Telesna površina ni vplivala na odziv na zdravljenje med 2-tedenskim UFO, niso pa opazili nobenega odziva pri pediatričnih bolnikih s kvalifikacijsko koncentracijo fosforja < 7,0 mg/dl.
For paediatric patients with a <1.2 BSA (m2), the oral suspension should be administered, as tablet formulations were not tested in this population and therefore are not appropriate for this population.
Pediatrični bolniki s telesno površino < 1,2 m morajo zdravilo dobiti v peroralni suspenziji, ker tablete v tej populaciji niso preizkušene in zato zanjo niso primerne.
These symptoms can be due to serious inflammatory bowel disease caused by sevelamer crystals deposit in your bowel.
Ti simptomi so lahko posledica resne vnetne bolezni črevesa zaradi odlaganja kristalov sevelamerja v črevesju.
Constipation may be a preceding symptom.
Predhodni simptom je lahko zaprtje.
For doses of less than 0.8 g, the powder in the sachet may be divided.
Za odmerke, manjše od 0,8 g, je mogoče prašek v vrečici razdeliti.
Pharmacotherapeutic group: All other therapeutic products, drugs for treatment of hyperkalemia and hyperphosphataemia.
Farmakoterapevtska skupina: Druga nerazvrščena zdravila za različne bolezni, zdravila za zdravljenje hiperkaliemije in hiperfosfatemije.
Increased levels of serum phosphorus can lead to hard deposits in your body called calcification.
Povišane ravni fosforja v serumu lahko povzročijo nastajanje trdih skupkov snovi (depozit) v telesu, kar se imenuje kalcifikacija.
Sevelamer hydrochloride, which contains the same active moiety as sevelamer carbonate, has been given to normal healthy volunteers in doses of up to 14 grams per day for eight days with no adverse reactions.
Sevelamerijev klorid, ki vsebuje enako učinkovino kot sevelamerijev karbonat, so dajali zdravim prostovoljcem v odmerkih do 14 gramov na dan osem dni brez pojava neželenih učinkov.
If you forget to take Renvela
Če ste pozabili vzeti zdravilo Renvela
As an alternative to water, the powder may be pre-mixed with a small amount of beverage or food (e.g. 100grams/120 ml) and consumed within 30 minutes.
Kot alternativo za vodo lahko prašek predhodno pomešamo z majhno količino pijače ali hrane (npr. 100 gramov / 120 ml) in zaužijemo v 30 minutah.
*Plus subsequent titrating, see section “Titration and maintenance” Children/adolescents (>6 years of age and a BSA of >0.75m2) The recommended starting dose of sevelamer carbonate for children is between 2.4 g and 4.8 g per day based on the patient's BSA category.
*In nadaljnje titriranje, glejte poglavje “Titriranje in vzdrževanje” Otroci/mladostniki (stari > 6 let in s telesno površino > 0,75 m Priporočeni začetni odmerek sevelamerijevega karbonata za otroke je od 2,4 g do 4,8 g na dan na podlagi kategorije bolnikove telesne površine.
The phosphate serum level should be monitored and the Renvela dosage adjusted consequently.
Koncentracijo fosfata v serumu je treba kontrolirati in odmerjanje zdravila Renvela ustrezno prilagoditi.
- Allergic reaction (signs including rash, hives, swelling, trouble breathing).
- Alergijska reakcija (znaki vključujejo izpuščaj, koprivnico, otekanje, težave z dihanjem).
• Medicines treating heartburn and reflux from your stomach or oesophagus, such as omeprazole, pantoprazole, or lansoprazole, known as “proton pump inhibitors”, may reduce the efficacy of Renvela.
• Zdravila za zdravljenje zgage in vračanja kisline (refluksa) iz želodca ali požiralnika, ki jih imenujemo "zaviralci protonske črpalke" in med katere spadajo na primer omeprazol, pantoprazol in lansoprazol, lahko zmanjšajo učinkovitost zdravila Renvela.
In interaction studies in healthy volunteers, sevelamer hydrochloride, which contains the same active moiety as sevelamer carbonate, had no effect on the bioavailability of digoxin, warfarin, enalapril or metoprolol.
Ko so preučevali medsebojno delovanje pri zdravih prostovoljcih, ni imel sevelamerijev klorid, ki vsebuje enako učinkovino kot sevelamerijev karbonat, nobenega učinka na biološko uporabnost digoksina, varfarina, enalaprila ali metoprolola.
(Instructions for presentation with dosing spoon) The sachet has to be discarded after 24 hours of opening.
(Navodila za obliko z odmerno žličko) Vrečico je treba zavreči v roku 24 ur po odprtju.
Animal studies have shown some reproductive toxicity when sevelamer was administered to rats at high doses (see section 5.3).
Študije na živalih so pokazale vpliv na sposobnost razmnoževanja pri dajanju sevelamera podganam v visokih odmerkih (glejte poglavje 5.3).
For a 0.4 g dose: o Shake the sachet holding the top corner before opening, to move the powder to the bottom of the sachet o Open the sachet by tearing along the marked line.
Za odmerek 0,4 g: o Stresite vrečico tako, da jo pred odprtjem držite za zgornji vogal, da se prašek premakne na dno vrečice.
Renvela is indicated for the control of hyperphosphataemia in adult patients receiving haemodialysis or peritoneal dialysis.
Zdravilo Renvela je indicirano za nadzor hiperfosfatemije pri odraslih bolnikih, ki prejemajo hemodializo ali peritonealno dializo.
• active inflammatory bowel disease
• aktivno vnetno obolenje črevesa
Only for bottle label of 180 tablets: 2D barcode carrying the unique identifier included.
Samo za nalepko na vsebniku s 180 tabletami: Vsebuje dvodimenzionalno črtno kodo z edinstveno oznako.
Ciclosporin, mycophenolate mofetil and tacrolimus in transplant patients Reduced levels of ciclosporin, mycophenolate mofetil and tacrolimus have been reported in transplant patients when co-administered with sevelamer hydrochloride without any clinical consequences (e.g., graft rejection).
Ciklosporin, mofetilmikofenolat in takrolimus pri bolnikih po presaditvi Pri bolnikih po presaditvi so poročali o znižanih ravneh ciklosporina, mofetilmikofenolata in takrolimusa pri sočasnem dajanju s sevelamerijevim kloridom, kar pa ni imelo kliničnih posledic (npr. zavrnitve presadka).
Keep the bottle container tightly closed in order to protect from moisture.
Vsebnik shranjujte tesno zaprt za zagotovitev zaščite pred vlago.
The safety and effectiveness of sevelamer carbonate in hyperphosphatemic paediatric patients with CKD was evaluated in a multicenter study with a 2-week, randomised, placebo-controlled, fixed dose period (FDP) followed by a 6-month, single-arm, open-label, dose titration period (DTP).
Varnost in učinkovitost sevelamerijevega karbonata pri hiperfosfatemičnih pediatričnih bolnikih s KBL so ocenili v multicentrični študiji z dvema obdobjema: 2-tedenskim, randomiziranim, s placebom kontroliranim obdobjem uporabe fiksnega odmerka (UFO), ki mu je sledilo 6-mesečno obdobje titriranja odmerka (OTO) z eno samo skupino in odprtim načrtom zdravljenja.
Sevelamer carbonate does not contain any calcium.
Sevelamerijev karbonat ne vsebuje kalcija.
• have disturbed level of bicarbonate in your blood and increased acidity in the blood and other body tissue.
• če imate neustrezno koncentracijo bikarbonata v krvi in povečano kislost v krvi in drugih telesnih tkivih.
The recommended starting dose of this medicine for adults and elderly is 2.4-4.8g per day equally divided over three meals.
Priporočeni začetni odmerek tega zdravila pri odraslih in starejših je 2,4-4,8 g na dan, ki ga enakomerno razdelite med tri obroke.
Forty-nine (49) patients received sevelamer carbonate and 51 received placebo during the 2 week FDP.
Med 2-tedenskim UFO je 49 bolnikov prejemalo sevelamerijev karbonat in 51 placebo.
Sevelamer hydrochloride was not mutagenic in the Ames bacterial mutation assay.
Sevelamerijev klorid ni bil mutagen v Amesovem preskusu bakterijskih mutacij.
If you get any of the following side effects, seek immediate medical attention: - Allergic reaction (signs including rash, hives, swelling, trouble breathing).
Nemudoma poiščite zdravniško pomoč, če se vam pojavi kateri od naslednjih neželenih učinkov: - Alergijska reakcija (znaki vključujejo izpuščaj, koprivnico, otekanje, težave z dihanjem).
You should tell your doctor immediately if you experience any new signs or symptoms of abdominal distress, abdominal swelling, abdominal pain, abdominal tenderness, or abdominal rigidity, constipation, fever, chills, nausea or vomiting.
Svojega zdravnika takoj obvestite, če opazite kakršnekoli nove znake ali simptome težav v trebuhu, oteklosti trebuha, bolečin v trebuhu, občutljivosti ali otrdelosti trebuha, zaprtosti, zvišane telesne temperature, mrzlic, slabosti ali bruhanja.
You may develop peritonitis (infection of your abdominal fluid) associated with your peritoneal dialysis.
Razvije se lahko peritonitis (okužba potrebušnice), povezana s peritonealno dializo.
In patients not taking supplemental vitamins but on sevelamer, serum vitamin A, D, E and K status should be assessed regularly.
Pri bolnikih, ki ne jemljejo vitaminskih nadomestkov, a se zdravijo s sevelamerom, je treba ravni vitaminov A, D, E in K v serumu redno ocenjevati.
Patients with CKD may develop hypocalcaemia or hypercalcaemia.
Pri bolnikih s KBL lahko pride do hipokalcemije ali hiperkalcemije.
Studies in animals have shown that sevelamer did not impair fertility in male or female rats at exposures at a human equivalent dose 2 times the maximum clinical trial dose of 13 g/day, based on a comparison of relative BSA.
Študije na živalih so pokazale, da sevelamer ne vpliva na plodnost pri samcih in samičkah podgan pri izpostavljenosti odmerku, primerljivem dvakrat večjemu od največjega odmerka pri človeku v kliničnem preskušanju 13 g/dan, glede na primerjavo relativne površine telesa.
It binds phosphate from food in the digestive tract and so reduces serum phosphorus levels in the blood.
Ta veže fosfor iz hrane v prebavnem traktu in s tem zmanjša ravni fosforja v krvi.
Most of adverse events reported as related, or possibly related, to sevelamer carbonate were gastrointestinal in nature.
Večina neželenih učinkov, ki so bili zabeleženi kot povezani ali morebiti povezani s sevelamerijevim karbonatom, je bila povezana s prebavili.