natgillin/translations-raw huggingface dataset:
Placement or removal of an epidural catheter or lumbar puncture is best performed when the anticoagulant effect of enoxaparin sodium is low; however, the exact timing to reach a sufficiently low anticoagulant effect in each patient is not known.
Namestitev ali odstranitev epiduralnega katetra oz. lumbalno punkcijo je najbolje izvesti, ko je antikoagulantni učinek natrijevega enoksaparinata majhen, toda natančen čas, ko je dosežen dovolj majhen antikoagulantni učinek pri posameznem bolniku, ni znan.
It should not be mixed or co-administered with other medications.
Ne smete ga mešati ali uporabiti sočasno z drugimi zdravili.
If bleeding occurs, the origin of the haemorrhage should be investigated and appropriate treatment instituted.
Če se pojavi krvavitev, je treba ugotoviti njen vir in uvesti ustrezno zdravljenje.
Enoxaparin sodium has been evaluated in more than 15,000 patients who received enoxaparin sodium in clinical trials.
Natrijev enoksaparinat so ocenili pri več kot 15.000 bolnikih, ki so ga prejemali v kliničnih preskušanjih.
This decrease was mainly attributed to a decrease in ATIII level secondary to a reduced synthesis of ATIII in patients with hepatic impairment.
To zmanjšanje so pripisali predvsem zmanjšanju ravni ATIII zaradi zmanjšane sinteze ATIII pri bolnikih z okvaro jeter.
• are currently using medicines which affect bleeding (see section below - Other medicines).
• če trenutno uporabljate zdravila, ki vplivajo na strjevanje krvi (glejte spodaj - poglavje Druga
Also, tell your doctor if you have any problem with your spine or if you ever had spinal surgery.
Prav tako morate zdravniku povedati, če imate kakšne težave s hrbtenico, ali če ste kdaj imeli operacijo na hrbtenici.
If you experience any bleeding event that does not stop by itself or if you experience signs of excessive bleeding (exceptional weakness, tiredness, paleness, dizziness, headache or unexplained swelling), consult your doctor immediately.
Če se vam pojavi krvavitev, ki se ne ustavi sama od sebe, ali če se vam pojavijo znaki prekomerne krvavitve (izredna šibkost, utrujenost, bledica, omotica, glavobol ali nepojasnjeno otekanje), se takoj posvetujte z zdravnikom.
These anticoagulant activities are mediated through anti-thrombin III (ATIII) resulting in anti-thrombotic activities in humans.
Te antikoagulantne učinke posreduje antitrombin III (ATIII); posledica je antitrombotično delovanje pri človeku.
Start taking the direct oral anticoagulant 0-2 hours before the time you would have had the next injection, then continue as normal.
Neposredni peroralni antikoagulans začnite jemati 0 do 2 uri pred časom, ko bi bila na vrsti naslednja injekcija, nato nadaljujte kot običajno.
• you have ever had a reaction to heparin that caused a severe drop in the number of your platelets
• če ste kdaj imeli reakcijo na heparin, ki vam je povzročila hudo zmanjšanje števila trombocitov
Enoxaparin sodium treatment is prescribed for an average period of 10 days.
Zdravljenje z natrijevim enoksaparinatom se predpiše za povprečno 10 dni.
In humans, there is no evidence that enoxaparin crosses the placental barrier during the second and third trimester of pregnancy.
Pri človeku ni dokazov, da bi enoksaparin v drugem in tretjem trimesečju nosečnosti prehajal skozi placentno pregrado.
Before injecting yourself with Thorinane - Check the expiry date on the medicine.
Preden si injicirate zdravilo Thorinane - Preverite datum izteka roka uporabnosti na ovojnini.
Pre-filled syringe 2 years
Napolnjena injekcijska brizga 2 leti
In surgical patients, haemorrhage complications were considered major: (1) if the haemorrhage caused a significant clinical event, or (2) if accompanied by haemoglobin decrease ≥ 2 g/dL or transfusion of 2 or more units of blood products.
Pri kirurških bolnikih so bili krvavitveni zapleti ocenjeni kot hudi: (1) če je krvavitev povzročila pomemben kliničen dogodek, ali (2) če jo je spremljalo znižanje hemoglobina za ≥ 2 g/dl ali transfuzija 2 ali več enot krvnih pripravkov.
These factors are known to contribute to the overall antithrombotic effect of enoxaparin sodium.
Znano je, da ti faktorji pripomorejo k celotnemu antitrombotičnemu učinku natrijevega enoksaparinata.
Thorinane can be used during breastfeeding.
Zdravilo Thorinane se lahko uporablja med obdobjem dojenja.
See “Do not use Thorinane”.
Glejte tudi "Ne uporabljajte zdravila Thorinane".
Based on the results of a population pharmacokinetic analysis, the enoxaparin sodium kinetic profile is not different in elderly subjects compared to younger subjects when renal function is normal.
Na podlagi rezultatov analize populacijske farmakokinetike se kinetični profil natrijevega enoksaparinata pri starejših preiskovancih ne razlikuje od tistega pri mlajših, če je delovanje ledvic normalno.
When used as curative treatment, aPTT can be prolonged by 1.5-2.2 times the control time at peak activity.
Če je uporabljen za kurativno zdravljenje, se lahko aPTČ ob vrhu aktivnosti podaljša na 1,5- do 2,2-kratni kontrolni čas.
Likewise, consider not using enoxaparin sodium until at least 4 hours after the spinal/epidural puncture or after the catheter has been removed.
Prav tako ne uporabljajte natrijevega enoksaparinata, dokler ne minejo vsaj 4 ure po spinalni/epiduralni punkciji ali odstranitvi katetra.
Frequencies are defined as follows: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1000 to < 1/100); rare (≥ 1/10,000 to <1/1,000); and very rare (< 1/10,000) or not known (cannot be estimated from available data).
Opredelitev pogostnosti je: zelo pogosti (≥ 1/10), pogosti (≥ 1/100 do < 1/10), občasni (≥ 1/1000 do < 1/100), redki (≥ 1/10.000 do < 1/1.000) in zelo redki (< 1/10.000) ali neznana pogostnost (ni mogoče oceniti iz razpoložljivih podatkov) Pri vsakem organskem sistemu so neželeni učinki navedeni po padajoči resnosti.
• General
• Splošno
• Spinal/Epidural anaesthesia or lumbar puncture
• Spinalna/epiduralna anestezija ali lumbalna punkcija
• Rare: Cutaneous vasculitis*, skin necrosis* usually occurring at the injection site (these phenomena have been usually preceded by purpura or erythematous plaques, infiltrated and painful).
• Redki: Kožni vaskulitis*, nekroza kože*, ki se po navadi pojavi na mestu injiciranja (pred temi pojavi so se po navadi razvili purpura ali infiltrirani in boleči eritematozni plaki).
Enoxaparin is a LMWH with a mean molecular weight of approximately 4,500 daltons, in which the antithrombotic and anticoagulant activities of standard heparin have been dissociated.
Enoksaparin je NMH s povprečno molekulsko maso približno 4.500 daltonov, pri katerem sta antitrombotično in antikoagulantno delovanje standardnega heparina ločena.
The regimen should be selected by the physician based on an individual assessment including evaluation of the thromboembolic risk and of the risk of bleeding.
Shemo mora zdravnik izbrati na podlagi ocene posameznega bolnika, vključno z ovrednotenjem tveganja za trombembolijo in tveganja za krvavitev.
• Large red irregularly shaped skin lesions with or without blisters.
• Velike, rdeče kožne spremembe nepravilnih oblik, z mehurji ali brez njih.
Treatment with enoxaparin sodium is prescribed for at least 6 to 14 days whatever the recovery status (e.g. mobility).
Zdravljenje z natrijevim enoksaparinatom se predpiše za vsaj 6 do 14 dni, ne glede na stanje okrevanja (npr. mobilnost).
The decision to use enoxaparin sodium in such a case must be made only after a careful benefit risk assessment and after non-heparin alternative treatments are considered (e.g. danaparoid sodium or lepirudin).
Odločitev za uporabo natrijevega enoksaparinata sme biti v takšnem primeru narejena le po natančni oceni koristi in tveganja ter po razmisleku o drugih, neheparinskih možnosti zdravljenja (npr. natrijev danaparoid ali lepirudin).
- The other ingredient is water for injections.
- Druga sestavina zdravila je voda za injekcije.
However, even with high doses of protamine, the anti-Xa activity of enoxaparin sodium is never completely neutralized (maximum about 60%) (see the prescribing information for protamine salts).
Vendar pa anti-Xa aktivnosti natrijevega enoksaparinata ni mogoče nikoli povsem nevtralizirati niti z velikimi odmerki protamina (največ okrog 60 %) (glejte informacije za predpisovanje soli protamina).
If the combination is indicated, enoxaparin sodium should be used with careful clinical and laboratory monitoring when appropriate.
Če je kombinirano zdravljenje indicirano, je priporočljivo natrijev enoksaparinat uporabljati ob natančnem kliničnem in laboratorijskem nadzoru, kot je primerno.
These are more likely to appear in the area you have been injected with Thorinane.
Verjetnost zanje je večja v predelih, kamor ste si injicirali zdravilo Thorinane.
EXP The diluted solution must be used within 8 hours.
EXP Razredčeno raztopino porabite v 8 urah.
• The dose will depend on how likely you are to develop a clot.
• Odmerek bo odvisen od verjetnosti, da se vam pojavi strdek.
Do not start treatment with Thorinane until 12 hours after the final dose of direct oral anticoagulant.
Zdravljenja z zdravilom Thorinane ne začnite prej kot 12 ur po zadnjem odmerku neposrednega peroralnega antikoagulansa.
• Rare: Anaphylactic/Anaphylactoid reactions including shock*
• Redki: Anafilaktične/anafilaktoidne reakcije, vključno s šokom*
Stop using Thorinane and talk to a doctor or nurse at once if you get any signs of a severe allergic reaction (such as difficulty breathing, swelling of the lips, mouth, throat or eyes).
Nehajte uporabljati zdravilo Thorinane in se takoj posvetujte z zdravnikom ali medicinsko sestro, če se vam pojavi kakršen koli znak hude alergijske reakcije (na primer težko dihanje, oteklost ustnic, ust, žrela ali oči).
• Pink patches on your skin.
• Rožnate lise na koži.
As there is an interval before the VKA reaches its maximum effect, enoxaparin sodium therapy should be continued at a constant dose for as long as necessary in order to maintain the INR within the desired therapeutic range for the indication in two successive tests.
Ker je potreben določen čas, preden VKA doseže svoj največji učinek, je treba uporabo natrijevega enoksaparinata nadaljevati v stalnem odmerku, dokler je potrebno, da bi vrednost INR v dveh zaporednih testiranjih ohranili znotraj želenega terapevtskega območja za konkretno indikacijo.
• Increases in liver enzymes.
• Zvišanje jetrnih encimov.
• Percutaneous coronary revascularization procedures
• Postopki za perkutano koronarno revaskularizacijo
o For dosage in patients ≥ 75 years of age, see paragraph “Elderly”.
o Za odmerjanje pri bolnikih, starih ≥ 75 let, glejte odstavek "Starejše osebe".
: Platelet increased >400 G/L
: Povečanje števila trombocitov > 400 G/l
GREECE
Grčija
Enoxaparin sodium cannot be used interchangeably (unit for unit) with other LMWHs.
Natrijevega enoksaparinata ni mogoče uporabljati medsebojno zamenljivo (enota za enoto) z drugimi NMH.
The SC injections of enoxaparin sodium were given until hospital discharge or for a maximum of eight days (whichever came first).
Subkutane injekcije natrijevega enoksaparinata so dobivali do odpusta iz bolnišnice ali največ osem dni (kar od tega je bilo prej).
Anti-Xa levels are still detectable at these time points, and these delays are not a guarantee that neuraxial hematoma will be avoided.
Ob teh časih so koncentracije anti-Xa še zaznavne in takšni odlogi niso zagotovilo, da se ne bo pojavil nevraksialni hematom.
This medicine should be injected just under the skin on your stomach, but not too near the belly button or any scar tissue (at least 5 cm away from these).
Zdravilo injicirajte tik pod kožo na trebuhu, vendar ne v bližini popka ali brazgotine (vsaj 5 cm stran).
When the container is full, give it to your doctor or home care nurse for disposal.
Ko je zabojnik poln, ga predajte zdravniku ali patronažni sestri, da ga ustrezno zavrže.
• Your doctor will normally ask you to take aspirin (acetylsalicylic acid) as well.
• Praviloma vam bo zdravnik poleg tega predpisal tudi acetilsalicilno kislino.
• Decreased red blood cell count.
• Zmanjšanje števila rdečih krvnih celic
• Your doctor will decide how long you should receive Thorinane.
• Zdravnik bo določil, koliko časa morate prejemati zdravilo Thorinane.
D. CONDITIONS OR RESTRICTIONS WITH REGARD TO THE SAFE AND EFFECTIVE
D. POGOJI ALI OMEJITVE V ZVEZI Z VARNO IN
In lactating rats, the passage of enoxaparin or its metabolites in milk is very low.
Pri doječih podganah je prehajanje enoksaparina in njegovih presnovkov v mleko zelo majhno.
The syringe is pre-filled and ready to use.
Brizga je napolnjena in pripravljena za uporabo.
The volume of distribution of enoxaparin sodium anti-Xa activity is about 4.3 litres and is close to the blood volume.
Volumen porazdelitve aktivnosti anti-Xa natrijevega enoksaparinata je približno 4,3 litra in je podoben volumnu krvi.
Enoxaparin sodium regimen administered during these clinical trials varies depending on indications.
Sheme uporabe natrijevega enoksaparinata, uporabljene v teh kliničnih preskušanjih, so se razlikovale glede na indikacije.
• If you have restricted mobility due to illness, you will normally be given 4,000 IU (40 mg) of Thorinane each day.
• Če imate zaradi bolezni omejeno mobilnost, boste po navadi dobili 4.000 i.e. (40 mg) zdravila
The enoxaparin sodium dosing strategy was adjusted for severe renally impaired patients and for the elderly of at least 75 years of age.
Odmerjanje natrijevega enoksaparinata je bilo prilagojeno pri bolnikih s hudo okvaro ledvic in starejših bolnikih, starih vsaj 75 let.
After dilution is completed, the volume to be injected can be calculated using the following formula [Volume of diluted solution (mL) = Patient weight (kg) x 0.1] or using the table below.
Ko je razredčenje končano, lahko količino, ki jo je treba injicirati, izračunate po formuli [količina razredčene raztopine (ml) = bolnikova telesna masa (kg) x 0,1], ali uporabite spodnjo preglednico.
VTE = Venous thromboembolic events which included DVT, PE, and death considered to be thromboembolic in origin * p value versus placebo =0.0002
VTE = venski trombembolični dogodki; obsegali so GVT, PE in smrt, za katero je bilo ocenjeno, da je posledica trombembolije * Vrednost p v primerjavi s placebom = 0,0002
Elimination appears monophasic with a half-life of about 5 hours after a single SC dose to about 7 hours after repeated dosing.
Kaže, da je odstranjevanje enofazno; razpolovni čas je od 5 ur po uporabi enkratnega subkutanega odmerka do približno 7 ur po ponavljajočem se odmerjanju.
The administration should be alternated between the left and right anterolateral or posterolateral abdominal wall.
Injicirati je treba izmenjaje v levi in desni anterolateralni ali posterolateralni del trebušne stene.
Other adverse reactions observed in clinical studies and reported in post-marketing experience (* indicates reactions from post-marketing experience) are detailed below.
Drugi neželeni učinki, opaženi v kliničnih študijah in zabeleženi po prihodu zdravila na trg, so podrobno navedeni spodaj (* označuje učinke, zabeležene po prihodu zdravila na trg).
Dose adjustment based on monitoring of anti-Xa levels is unreliable in patients with liver cirrhosis and not recommended (see section 5.2).
Prilagajanje odmerka na podlagi nadzorovanja ravni anti-Xa je pri bolnikih s cirozo jeter nezanesljivo in ni priporočljivo (glejte poglavje 5.2).
6) Hold the syringe so that the needle is pointing downwards (vertically at a 90º angle).
6) Injekcijsko brizgo primite, tako da je igla usmerjena navzdol (navpično pod kotom 90°).
This results in differences in pharmacokinetics and associated biological activities (e.g. anti-thrombin activity, and platelet interactions).
Posledica tega so razlike v farmakokinetiki in spremljajočih bioloških učinkih (npr. antitrombinsko delovanje in medsebojno delovanje s trombociti).
The quantitative determination of anti-Xa and anti-IIa pharmacokinetic activities was conducted by validated amidolytic methods.
Farmakokinetična aktivnost anti-Xa in anti-IIa je bila kvantitativno določena z validiranimi amidolitičnimi metodami.
Thorinane is a biosimilar medicinal product.
Thorinane je podobno biološko zdravilo.
Pregnant women receiving enoxaparin sodium should be carefully monitored for evidence of bleeding or excessive anticoagulation and should be warned of the haemorrhagic risk.
Nosečnice, ki prejemajo natrijev enoksaparinat, je treba natančno nadzorovati glede znakov krvavitev ali prekomerne antikoagulacije in jih je treba opozoriti na tveganje za krvavitve.
If signs or symptoms of spinal hematoma are suspected, initiate urgent diagnosis and treatment including consideration for spinal cord decompression even though such treatment may not prevent or reverse neurological sequelae.
Če obstaja sum na znake ali simptome spinalnega hematoma, je treba začeti nujno diagnostiko in zdravljenje, vključno z dekompresijo hrbtenjače, čeprav takšno zdravljenje morda ne bo preprečilo ali odpravilo nevroloških posledic.
• You bruise more easily than usual.
• Bolj kot po navadi ste nagnjeni k podplutbam.
Obese patients are at higher risk for thromboembolism.
Debeli bolniki imajo večje tveganje za trombembolijo.
Thorinane can be used for two different types of heart attack called STEMI (ST segment elevation myocardial infarction) or Non STEMI (NSTEMI).
Zdravilo Thorinane se lahko uporablja za dve različni vrsti srčnega infarkta: STEMI (srčni infarkt z dvigom spojnice ST) ali ne-STEMI (NSTEMI).
What Thorinane is and what it is used for What you need to know before you use Thorinane How to use Thorinane
Kaj je zdravilo Thorinane in za kaj ga uporabljamo Kaj morate vedeti, preden boste uporabili zdravilo Thorinane
Remember: Do not inject yourself within 5 cm of your belly button or around existing scars or bruises.
Ne pozabite: Zdravila ne injicirajte v predelu 5 cm okoli popka ali okrog brazgotin ali podplutb.
• If you are using Thorinane to treat blood clots in your body and going to receive spinal or epidural anaesthesia or lumbar puncture within 24 hours.
• Če uporabljate Thorinane za zdravljenje krvnih strdkov in imate v 24 urah predvideno spinalno anestezijo, epiduralno anestezijo ali lumbalno punkcijo.
• Osteoporosis (a condition where your bones are more likely to break) after long term use.
• Osteoporoza (stanje, povezano z večjo verjetnostjo za zlome krvi) po dolgotrajni uporabi.
- Check your abdomen to see if the last injection caused any redness, change in skin colour, swelling,
- Preglejte trebuh in se prepričajte, da zadnja injekcija ni povzročila pordelosti, spremembe v barvi kože, otekline, izcedka ali bolečine.
Enoxaparin sodium or standard heparin therapy was administered for a minimum of 5 days and until the targeted warfarin sodium INR was achieved.
Natrijev enoksaparinat ali običajno heparinsko zdravljenje so uporabljali najmanj 5 dni in dokler ni bilo doseženo ciljno INR natrijevega varfarinata.
For treatment of acute STEMI in elderly patients ≥75 years of age, an initial IV bolus must not be used.
Za zdravljenje akutnega STEMI pri starejših bolnikih, starih ≥ 75 let, se ne sme uporabiti začetnega intravenskega bolusa.
As with other anticoagulants, haemorrhage may occur in the presence of associated risk factors such as: organic lesions liable to bleed, invasive procedures or the concomitant use of medications affecting haemostasis (see sections 4.4 and 4.5).
Tako kot pri drugih antikoagulansih se krvavitev lahko pojavi v prisotnosti spremljajočih dejavnikov tveganja, npr.: organskih lezij, nagnjenih h krvavitvi, invazivnih posegov ali sočasne uporabe zdravil, ki vplivajo na hemostazo (glejte poglavji 4.4 in 4.5).
There were no significant differences in major haemorrhages, although a haemorrhage at the site of the SC injection was more frequent.
Značilnih razlik glede večjih krvavitev ni bilo, čeprav so bile krvavitve na mestu subkutane injekcije pogostejše.
Animal studies did not show any effect on fertility (see section 5.3).
Študije na živalih niso pokazale učinkov na plodnost (glejte poglavje 5.3).
• Lost of control over your bladder or bowel (so you cannot control when you go to the toilet).
• Izguba nadzora nad sečnim mehurjem ali črevesjem (tako da ne morete obvladati odvajanja).
• If you have had a reaction to heparin that caused a severe drop in the number of your clotting cells (platelets) - this reaction is called heparin-induced thrombocytopenia - within the last 100 days or if you have antibodies against enoxaparin in your blood.
• Če ste imeli v zadnjih 100 dneh reakcijo na heparin, ki je povzročila hudo zmanjšanje števila trombocitov (krvnih ploščic) - takšno reakcijo imenujemo s heparinom izzvana trombocitopenija - ali če imate v krvi protitelesa proti enoksaparinu.
In order to improve the LMWH traceability, it is recommended that health care professionals record the trade name and batch number of the administered product in the patient file.
Za izboljšanje sledljivosti NMH je priporočljivo, da zdravstveni delavci v bolnikovo dokumentacijo vpišejo ime in številko serije uporabljenega zdravila.
What you need to know before you use Thorinane
Kaj morate vedeti, preden boste uporabili zdravilo Thorinane
If the treatment with enoxaparin sodium is to be continued, the next scheduled dose should be given no sooner than 6 to 8 hours after sheath removal.
Če naj se zdravljenje z natrijevim enoksaparinatom nadaljuje, se naslednjega predvidenega odmerka ne sme uporabiti prej kot 6 do 8 ur po odstranitvi ovojnice.
• Medicines which increase potassium level in your blood such as potassium salts, water pills, some medicines for heart problems.
• Zdravila, ki povečajo koncentracijo kalija v krvi, na primer kalijeve soli, tablete za odvajanje vode, nekatera zdravila za težave s srcem.
7) Press down on the plunger with your finger.
7) S prstom pritisnite bat.
Having this medicine
Prejemanje tega zdravila
Paediatric population The safety and efficacy of enoxaparin sodium in children have not been established (see section 4.2).
Pediatrična populacija Varnost in učinkovitost natrijevega enoksaparinata pri otrocih nista ugotovljeni (glejte poglavje 4.2).
What Thorinane is and what it is used for
Kaj je zdravilo Thorinane in za kaj ga uporabljamo
Treatment of acute STEMI (patients under 75)
Zdravljenje akutnega STEMI (bolniki, mlajši od 75 let)
• Dextran injection - used as a blood replacer
• Injekcije dekstrana - uporablja se kot nadomestek krvi.
• At the same time you will also be given Thorinane as an injection underneath your skin (subcutaneous injection).
• Obenem boste dobili zdravilo Thorinane tudi v injekciji pod kožo (subkutano).
If there is a need for earlier than 12 hours enoxaparin sodium preoperative prophylactic initiation (e.g. high risk patient waiting for a deferred orthopaedic surgery), the last injection should be administered no later than 12 hours prior to surgery and resumed 12 hours after surgery.
Če obstaja potreba po uvedbi profilakse z natrijevim enoksaparinatom več kot 12 ur pred operacijo (npr. bolniki z velikim tveganjem, ki čakajo na odloženo ortopedsko operacijo), je treba zadnjo injekcijo dati najpozneje 12 ur pred operacijo in uporabo znova začeti 12 ur po operaciji.
The 3,000 IU (30 mg) dose can then be directly injected into the IV line.
Odmerek 3.000 i.e. (30 mg) lahko potem neposredno injicirate v intravensko linijo.
In case a closure device is used, the sheath can be removed immediately.
Če uporabite zaporni pripomoček, lahko ovojnico odstranite nemudoma.
• Uncommon: Bullous dermatitis
• Občasni: Bulozni dermatitis
Acute coronary syndrome: treatment of unstable angina and NSTEMI and treatment of acute STEMI
Akutni koronarni sindrom: Zdravljenje nestabilne angine pektoris in NSTEMI ter zdravljenje akutnega STEMI
The pre-filled disposable syringe is ready for immediate use.
Napolnjena injekcijska brizga je pripravljena za takojšnjo uporabo.
Enoxaparin sodium is primarily metabolized in the liver by desulfation and/or depolymerization to lower molecular weight species with much reduced biological potency.
Natrijev enoksaparinat se presnovi predvsem v jetrih z desulfuracijo in/ali depolimerizacijo v vrste z manjšo molekulsko maso in veliko manjšo biološko močjo.