natgillin/translations-raw huggingface dataset:
If you develop a fever that does not go away, bruise or bleed very easily or look very pale, call your doctor right away.
Če se pri vas pojavi zvišana telesna temperatura, ki ne mine, blage podplutbe ali zlahka zakrvavite ali pa ste zelo bledi, takoj pokličite svojega zdravnika.
Systemic infections (including sepsis, candidiasis and influenza), intestinal infections (including gastroenteritis viral), skin and soft tissue infections (including paronychia, cellulitis, impetigo, necrotising fasciitis and herpes zoster), ear infections, oral infections (including herpes simplex, oral herpes and tooth infections), reproductive tract infections (including vulvovaginal mycotic infection),
črevesne okužbe (vključno z virusnim gastroenteritisom), okužbe kože in mehkih tkiv (vključno z zanohtnico, celulitisom, impetigom,
First dose of 160 mg (four 40 mg injections in one day or two 40 mg injections per day for two consecutive days), followed by 80 mg (two 40 mg injections in one day) two weeks later.
Prvi odmerek je 160 mg (štiri 40 mg injekcije v enem dnevu ali dve 40 mg injekciji na dan dva zaporedna dneva), čemur sledi 80 mg (dve 40 mg injekciji v enem dnevu) dva tedna kasneje.
Adequate data from treating patients who are carriers of HBV with anti-viral therapy in conjunction with TNF-antagonist therapy to prevent HBV reactivation are not available.
Pri bolnikih, ki so pozitivni na okužbo s hepatitisom B, se priporoča posvetovanje z zdravnikom specialistom za zdravljenje okužb s hepatitisom B. Nosilce HBV, ki potrebujejo zdravljenje z zdravilom Humira, je treba ves čas zdravljenja in več mesecev po koncu zdravljenja natančno spremljati glede znakov in simptomov aktivne okužbe s HBV. O zdravljenju nosilcev HBV s protivirusno terapijo v kombinaciji z antagonistom TNF za preprečitev reaktivacije HBV ni zadostnih podatkov.
RA study III evaluated 619 patients with moderately to severely active rheumatoid arthritis who were  18 years old, and who had an ineffective response to methotrexate at doses of 12.5 to 25 mg or have been intolerant to 10 mg of methotrexate every week.
V študiji revmatoidnega artritisa III je bilo ocenjeno 619 bolnikov z zmerno do hudo aktivnim revmatoidnim artritisom, starih ≥ 18 let, ki se niso učinkovito odzvali na odmerke metotreksata od
Tuberculosis, including reactivation and new onset of tuberculosis, has been reported in patients receiving Humira.
Pri bolnikih, zdravljenih z zdravilom Humira, so poročali o tuberkulozi, vključno z reaktivacijo in novimi pojavi tuberkuloze.
PASI 75 and PGA of clear or minimal response rates in these patients were 74.7% and 59.0%, respectively, after an additional 108 weeks of open-label therapy (total of 160 weeks).
Po dodatnih 108 tednih odprtega zdravljenja (skupaj 160 tednov) sta bila pri teh bolnikih delež odziva PASI 75 74,7 % in delež odziva PGA "čisto" ali "minimalno" 59,0 %.
Humira 80 mg solution for injection in pre-filled pen EU/1/03/256/021
Humira 80 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku EU/1/03/256/021
First dose of 160 mg (four 40 mg injections in one day or two 40 mg injections per day for two consecutive days), followed by an 80 mg dose (two 40 mg injections in one day) two weeks later.
Prvi odmerek je 160 mg (štiri 40 mg injekcije v enem dnevu ali dve 40 mg injekciji na dan dva zaporedna dneva), čemur sledi 80 mg odmerek (dve 40 mg injekciji v enem dnevu) dva tedna kasneje.
In some rare cases, especially if you are taking other medicines that suppress the immune system, reactivation of HBV can be life-threatening.
V redkih primerih, zlasti če uporabljate druga zdravila, ki zavirajo imunski sistem, je reaktivacija HBV
Humira 40 mg solution for injection in pre-filled pen EU/1/03/256/007
Humira 40 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku EU/1/03/256/007
Humira 40 mg solution for injection in vials is supplied as a sterile solution of 40 mg adalimumab dissolved in 0.8 ml solution.
Zdravilo Humira 40 mg raztopina za injiciranje v vialah je na voljo kot sterilna raztopina 40 mg adalimumaba, raztopljenega v 0,8 ml raztopine.
Humira 40 mg solution for injection in pre-filled pen EU/1/03/256/016
Humira 40 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku EU/1/03/256/016
Humira is used to treat moderate to severe chronic plaque psoriasis in adults.
Zdravilo Humira se uporablja za zdravljenje zmerne do hude kronične luskavice pri odraslih.
Results from both studies demonstrated statistically significant reduction of the risk of treatment failure in patients treated with Humira versus patients receiving placebo (See Table 29).
Klinični odziv Rezultati iz obeh študij kažejo statistično značilno zmanjšanje tveganja za neuspeh zdravljenja pri bolnikih, ki so prejemali zdravilo Humira, v primerjavi z bolniki, ki so prejemali placebo (glejte preglednico 29).
Results from both studies demonstrated statistically significant reduction of the risk of treatment failure in patients treated with Humira versus patients receiving placebo (See Table 19).
Klinični odziv Rezultati iz obeh študij kažejo statistično značilno zmanjšanje tveganja za neuspeh zdravljenja pri bolnikih, ki so prejemali zdravilo Humira, v primerjavi z bolniki, ki so prejemali placebo (glejte preglednico 19).
• 1 pre-filled pen (0.4 ml sterile solution), with 2 alcohol pads in a blister.
• 1 napolnjen injekcijski peresnik (0,4 ml sterilne raztopine) z 2 alkoholnima zložencema v pretisnem omotu.
One 0.4 ml pre-filled syringe contains 40 mg adalimumab.
Ena 0,4 ml napolnjena injekcijska brizga vsebuje 40 mg adalimumaba.
Humira 20 mg solution for injection in pre-filled syringe adalimumab
Humira 20 mg raztopina za injiciranje v napolnjeni injekcijski brizgi adalimumab
Non-infectious uveitis
Neinfekcijski uveitis
b p-value is from the pairwise comparison of Humira monotherapy and Humira/methotrexate combination therapy using the Mann-Whitney U test c p-value is from the pairwise comparison of Humira monotherapy and methotrexate monotherapy using the Mann-Whitney U test
Celotna Sharpova ocena Ocena erozij Seštevek JSN a Vrednost p se nanaša na parno primerjavo monoterapije z metotreksatom in kombinirane terapije z zdravilom Humira/metotreksatom z Mann-Whitneyevim testom U b Vrednost p se nanaša na parno primerjavo monoterapije z zdravilom Humira in kombinirane terapije z zdravilom Humira/metotreksatom z Mann-Whitneyevim testom U c Vrednost p se nanaša na parno primerjavo monoterapije z zdravilom Humira in monoterapije z metotreksatom z Mann-Whitneyevim testom U.
All p-values are pairwise comparisons of proportions for Humira versus placebo * p < 0.001
Vse vrednosti p so za parne primerjave deležev med zdravilom Humira in placebom.
• 1 pre-filled pen (0.8 ml sterile solution), with 2 alcohol pads in a blister.
• 1 napolnjen injekcijski peresnik (0,8 ml sterilne raztopine) z 2 alkoholnima zložencema v pretisnem omotu.
Results from both studies demonstrated statistically significant reduction of the risk of treatment failure in patients treated with Humira versus patients receiving placebo (See Table 24).
Klinični odziv Rezultati iz obeh študij kažejo statistično značilno zmanjšanje tveganja za neuspeh zdravljenja pri bolnikih, ki so prejemali zdravilo Humira, v primerjavi z bolniki, ki so prejemali placebo (glejte preglednico 24).
ASAS Partial Remission BASDAI
ASAS delno izboljšanje BASDAIb50
Solution for injection 1 pre-filled pen 2 alcohol pads
raztopina za injiciranje 1 napolnjen injekcijski peresnik 2 alkoholna zloženca
• Check with your doctor before your child receives any vaccines.
• Preden vaš otrok opravi kakršno koli cepljenje, se posvetujte z zdravnikom.
It is important that you tell your doctor if your child has symptoms of infections, for example, fever, wounds, feeling tired, dental problems.
Pomembno je, da zdravniku poveste, če ima vaš otrok simptome okužb, npr. zvišano telesno temperaturo, rane, občutek utrujenosti ali težave z zobmi.
Intestinal perforation
Avtoimuna obolenja
• fatty liver
• zamaščenost jeter
In paediatric patients with moderate to severe CD, the open-label adalimumab induction dose was 160/80 mg or 80/40 mg at Weeks 0 and 2, respectively, dependent on a body weight cut-off of 40 kg. At Week 4, patients were randomised 1:1 to either the Standard Dose (40/20 mg eow) or Low Dose (20/10 mg eow) maintenance treatment groups based on their body weight.
Pediatrični bolniki z zmerno do hudo Crohnovo boleznijo so odvisno od njihove telesne mase (več ali manj od 40 kg) dobivali odprt začetni odmerek adalimumaba 160/80 mg v 0. tednu in 80/40 mg v
There is no relevant use of Humira in children aged less than 2 years in this indication.
Uporaba zdravila Humira pri otrocih, mlajših od 2 let, za to indikacijo ni primerna.
• The following instructions explain how to give yourself a subcutaneous injection of Humira using the pre-filled pen.
• Naslednja navodila pojasnjujejo, kako si subkutano injicirati zdravilo Humira z napolnjenim injekcijskim peresnikom.
In RA studies I-IV, all individual components of the ACR response criteria (number of tender and swollen joints, physician and patient assessment of disease activity and pain, disability index (HAQ) scores and CRP (mg/dl) values) improved at 24 or 26 weeks compared to placebo.
NP NP a Študija revmatoidnega artritisa I po 24 tednih, študija revmatoidnega artritisa II po 26 tednih in študija revmatoidnega artritisa III po 24 in 52 tednih b 40 mg zdravilo Humira vsak drugi teden c MTX = metotreksat **p < 0,01, zdravilo Humira v primerjavi s placebom; V študijah revmatoidnega artritisa I-IV so se v primerjavi s placebom po 24 oz. 26 tednih izboljšali vsi posamezni elementi meril odziva po ACR (število bolečih in oteklih sklepov, zdravnikova in bolnikova ocena aktivnosti bolezni in bolečin, vrednost indeksa invalidnosti (HAQ) in vrednost CRP
If your child develops a fever that does not go away, develops light bruises or bleeds very easily or looks very pale, call your doctor right away.
Če vaš otrok dobi zvišano telesno temperaturo, ki ne mine, če se mu pojavljajo podplutbe, zlahka zakrvavi ali je zelo bled, se takoj posvetujte s svojim zdravnikom.
This will include a thorough medical evaluation including your child's medical history and appropriate screening tests (for example chest X-ray and a tuberculin test).
To bo vključevalo natančno zdravniško oceno vključno s poizvedbo o zdravju vašega otroka v preteklosti in ustrezne preiskave (npr. rentgensko slikanje prsnega koša in tuberkulinski test).
• Tell your doctor if you are taking azathioprine or 6-mercaptopurine with Humira.
• Povejte zdravniku, če jemljete azatioprin ali 6-merkaptopurin sočasno z zdravilom
Please check with your doctor before you receive any vaccines.
Preden opravite kakršnokoli cepljenje, se posvetujte z zdravnikom.
If there are more than a few drops of liquid on the injection site, contact your doctor, nurse or pharmacist.
• Če menite, da niste dali polnega odmerka, se posvetujte z zdravnikom, farmacevtom ali medicinsko sestro.
It is important that you tell your doctor if you have symptoms of infections, for example, fever, wounds, feeling tired, dental problems.
Pomembno je, da zdravniku poveste, če imate simptome okužb, na primer zvišano telesno temperaturo, rane, občutek utrujenosti ali težave z zobmi.
The primary endpoint in RA study V was the percent of patients who achieved an ACR 50 response at Week 52.
Primarna končna točka študije revmatoidnega artritisa V je bil odstotek bolnikov, ki so do
If you accidentally inject Humira more frequently than told to by your doctor or pharmacist, call your doctor or pharmacist and tell him/her that you have taken more.
Če pomotoma injicirate zdravilo Humira pogosteje, kot vam je naročil zdravnik ali farmacevt, se morate posvetovati z njim ali s farmacevtom in mu povedati, da ste uporabili večji odmerek.
Humira 40 mg solution for injection in pre-filled syringe Each 0.8 ml single dose pre-filled syringe contains 40 mg of adalimumab.
Humira 40 mg raztopina za injiciranje v napolnjeni injekcijski brizgi Ena 0,8 ml napolnjena injekcijska brizga z enim odmerkom vsebuje 40 mg adalimumaba.
• hearing loss, buzzing
• izguba sluha, šumenje v ušesih
In controlled Phase 3 trials of Humira in patients with Crohn's disease and ulcerative colitis with a control period ranging from 4 to 52 weeks.
V kontroliranih preskušanjih faze 3 z zdravilom Humira pri bolnikih z revmatoidnim artritisom in psoriatičnim artritisom s trajanjem kontrolnega obdobja od 4 do 104 tedne, so se zvišanja ALT ≥ 3 x
Keep the pre-filled syringe in the outer carton in order to protect from light.
Napolnjen peresnik shranjujte v zunanji ovojnini za zagotovitev zaščite pred svetlobo.
< 40 kg • 40 mg at Week 0 and 20 mg at Week 2
40 mg 2. teden oziroma 40 mg 0. teden in 20 mg 2. teden.
• fatty liver;
• zamaščenost jeter;
The usual dose regimen for hidradenitis suppurativa is an initial dose of 160 mg (as four 40 mg injections in one day or two 40 mg injections per day for two consecutive days), followed by an 80 mg dose (as two 40 mg injections in one day) two weeks later.
Običajni začetni odmerek je 160 mg (kot štiri 40 mg injekcije v enem dnevu ali kot dve 40 mg injekciji na dan dva zaporedna dneva), ki mu sledi 80 mg (kot dve 40 mg injekciji v enem dnevu) dva tedna kasneje.
It is important to tell your doctor if your child gets symptoms such as fever, wounds, feeling tired or dental problems.
Pomembno je, da zdravniku poveste, če se pri vašem otroku pojavijo simptomi, kot so npr. zvišana telesna temperatura, rane, občutek utrujenosti ali težave z zobmi.
p = 0.031
< 0,001c
Humira 40 mg solution for injection in pre-filled syringe Each 0.4 ml single dose pre-filled syringe contains 40 mg of adalimumab.
Humira 40 mg raztopina za injiciranje v napolnjeni injekcijski brizgi Ena 0,4 ml napolnjena injekcijska brizga z enim odmerkom vsebuje 40 mg adalimumaba.
• 2 pre-filled syringes (0.8 ml sterile solution), each with 1 alcohol pad, in a blister.
• 2 napolnjeni injekcijski brizgi (0,8 ml sterilne raztopine), vsaka z 1 alkoholnim zložencem, v pretisnem omotu.
DO NOT push the white plunger rod past the dose position.
belega nosilca bata preko položaja za odmerek.
Do not remove the pre-filled pen while the injection is being given.
Napolnjenega injekcijskega peresnika med injiciranjem ne smete odstraniti.
• Plaque psoriasis
• luskavice (psoriaze) v plakih
After proper training, the injection can be self-administered or given by another person, for example a family member or friend.
Po ustreznem urjenju si lahko injekcije dajete sami ali vam jih daje kdo drug, npr. svojec ali prijatelj.
• If you experience allergic reactions with symptoms such as chest tightness, wheezing, dizziness, swelling or rash do not inject more Humira and contact your doctor immediately since, in rare cases, these reactions can be life threatening.
• Če doživite alergijske reakcije s simptomi, kot so tiščanje v prsih, piskajoče dihanje, omotica, otekanje ali izpuščaj, zdravila Humira ne injicirajte več in se takoj posvetujte s svojim zdravnikom, saj so v redkih primerih te reakcije lahko življenje ogrožajoče.
• If your child experiences allergic reactions with symptoms such as chest tightness, wheezing, dizziness, swelling or rash do not inject more Humira and contact your doctor immediately since, in rare cases, these reactions can be life threatening.
• Če vaš otrok doživi alergijske reakcije s simptomi, kot so tiščanje v prsih, piskajoče dihanje, omotica, otekanje ali izpuščaj, zdravila Humira ne injicirajte več in se takoj posvetujte s svojim zdravnikom, saj so v redkih primerih te reakcije lahko življenje ogrožajoče.
Humira Pre-filled Pen
OVOJNINAH NALEPKA NA PERESNIKU
Hepatitis reactivation of hepatitis B
• hepatitis • reaktivacija hepatitisa B
• 2 pre-filled syringes (0.4 ml sterile solution), each with 1 alcohol pad, in a blister.
• 2 napolnjeni injekcijski brizgi (0,4 ml sterilne raztopine), vsaka z 1 alkoholnim zložencem, v pretisnem omotu.
Lipids increased
• povečano potenje
• 4 pre-filled syringes (0.8 ml sterile solution), each with 1 alcohol pad, in a blister.
• 4 napolnjene injekcijske brizge (0,8 ml sterilne raztopine), vsaka z 1 alkoholnim zložencem, v pretisnem omotu.
• 6 pre-filled syringes (0.8 ml sterile solution), each with 1 alcohol pad, in a blister.
• 6 napolnjenih injekcijskih brizg (0,8 ml sterilne raztopine), vsaka z 1 alkoholnim zložencem, v pretisnem omotu.
• blood in urine
• kri v urinu • težave z ledvicami
Hold the pre-filled syringe with the needle facing up.
Napolnjeno injekcijsko brizgo primite, tako da je igla obrnjena navzgor.
Humira 40 mg solution for injection in pre-filled syringe is supplied as a sterile solution of 40 mg adalimumab dissolved in 0.4 ml solution.
Zdravilo Humira 40 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku je na voljo kot sterilna raztopina 40 mg adalimumaba, raztopljenega v 0,4 ml raztopine.
Humira 40 mg solution for injection in pre-filled syringe is supplied as a sterile solution of 40 mg adalimumab dissolved in 0.8 ml solution.
Zdravilo Humira 40 mg raztopina za injiciranje v napolnjenem injekcijskem peresniku je na voljo kot sterilna raztopina 40 mg adalimumaba, raztopljenega v 0,8 ml raztopine.
• 4 pre-filled syringes (0.4 ml sterile solution), each with 1 alcohol pad, in a blister.
• 4 napolnjene injekcijske brizge (0,4 ml sterilne raztopine), vsaka z 1 alkoholnim zložencem, v pretisnem omotu.
Some of those patients were also treated with azathioprine or 6- mercaptopurine.
Nekateri od teh bolnikov so bili zdravljeni tudi z azatioprinom ali
Your child should not take Humira with medicines containing the following active substances due to increased risk of serious infection:
Zaradi povečanega tveganja za resne okužbe vaš otrok zdravila Humira ne sme jemati z zdravili, ki vsebujejo naslednje učinkovine:
• inflammations
• zardevanje
Humira 80 mg solution for injection in pre-filled syringe with automatic needle guard Humira 80 mg solution for injection in single-use pre-filled syringe with automatic needle guard.
Zdravilo Humira 80 mg raztopina za injiciranje v napolnjeni injekcijski brizgi z avtomatskim ščitnikom za iglo za enkratno uporabo.
Packs of: 1 pre-filled syringe with needle guard (0.8 ml sterile solution) in a blister, and 1 alcohol pad.
1 napolnjena injekcijska brizga s ščitnikom za iglo (0,8 ml sterilne raztopine) v pretisnem omotu in
• liver failure
• odpoved jeter
During the controlled portions of pivotal Humira trials in adults of at least 12 weeks in duration in patients with moderately to severely active rheumatoid arthritis, ankylosing spondylitis, axial spondyloarthritis without radiographic evidence of AS, psoriatic arthritis, psoriasis, hidradenitis suppurativa, Crohn's disease, ulcerative colitis and uveitis, malignancies, other than lymphoma and non-melanoma skin cancer,
Ta preskušanja so vključila bolnike z revmatoidnim artritisom (tako tiste, ki so imeli bolezen kratek čas, kot tiste, ki so jo imeli že dolgo), juvenilnim idiopatskim artritisom (poliartikularnim juvenilnim idiopatskim artritisom in artritisom, povezanim z entezitisom), aksialnim spondiloartritisom, (ankilozirajočim sponditisom in aksialnim spondiloartritisom brez radiografskega dokaza za AS), psoriatičnim artritisom, Crohnovo boleznijo, ulceroznim kolitisom, psoriazo, hidradenitis suppurativa in uveitisom.
• 6 pre-filled syringes (0.4 ml sterile solution), each with 1 alcohol pad, in a blister.
• 6 napolnjenih injekcijskih brizg (0,4 ml sterilne raztopine), vsaka z 1 alkoholnim zložencem, v pretisnem omotu.
Ελλάδα
vnetje občasni
Needle Cover
Pokrovček igle
Humira 40 mg solution for injection in pre-filled syringe with needle guard Humira 40 mg solution for injection in single-use pre-filled syringe (type I glass) with needle guard for hospital and caregiver use.
Zdravilo Humira 40 mg raztopina za injiciranje v napolnjeni injekcijski brizgi (steklo tipa I) za enkratno uporabo, opremljeni s ščitnikom za iglo, za zdravniško in bolnišnično uporabo.
Humira b/ MTX n=63
Zdravilo Humirab/ MTXc n = 63
This will include a thorough medical evaluation including your medical history and appropriate screening tests (for example chest X-ray and a tuberculin test).
To bo vključevalo natančno zdravniško oceno vključno s poizvedbo o vašem zdravju v preteklosti in ustrezne preiskave (npr. rentgensko slikanje prsnih organov in tuberkulinski test).
If you develop a fever that does not go away, develop light bruises or bleed very easily or look very pale, call your doctor right away.
Če se pri vas pojavi zvišana telesna temperatura, ki ne mine, če se vam pojavljajo blage podplutbe, zlahka zakrvavite ali ste zelo bledi, takoj pokličite svojega zdravnika.
Humira/methotrexate patients demonstrated significantly less radiographic progression than patients receiving methotrexate alone at 6 and 12 months (see Table 11).
Pri bolnikih, ki so dobivali zdravilo Humira in metotreksat, je bilo po 6 in 12 mesecih (glejte preglednico 11)
• If you get allergic reactions with symptoms such as chest tightness, wheezing, dizziness, swelling or rash do not inject more Humira and contact your doctor immediately since, in rare cases, these reactions can be life threatening.
• Če se pri vas pojavijo alergijske reakcije s simptomi, kot so tiščanje v prsih, piskajoče dihanje, omotica, otekanje ali izpuščaj, zdravila Humira ne injicirajte več in se takoj posvetujte s svojim zdravnikom, saj so v redkih primerih te reakcije lahko življenje ogrožajoče.
In Psoriasis Study I, 28% of patients who were PASI 75 responders and were re-randomised to placebo at Week 33 compared to 5% continuing on Humira, p < 0.001, experienced “loss of adequate response” (PASI score after Week 33 and on or before Week 52 that resulted in a <PASI 50 response relative to baseline with a minimum of a 6-point increase in PASI score relative to Week 33).
V študiji pri psoriazi I so 33. teden "izgubo ustreznega odziva" zabeležili pri 28 % bolnikov, ki so dosegli odziv PASI 75 in so bili ob ponovni randomizaciji razvrščeni na placebo, in pri 5 % bolnikov,
• Advise your doctor if you have a history of recurrent infections or other conditions that increase the risk of infections.
• Zdravniku povejte, če ste imeli v preteklosti ponavljajoče se okužbe ali druge bolezni, ki zvečujejo tveganje za okužbe.
What you need to know before you use humira
Kaj morate vedeti, preden boste uporabili zdravilo Humira Ne uporabljajte zdravila Humira:
d score methotrexate
Activity Score)
Do not freeze.
Ne drgnite.
• respiratory tract infections (including cold, runny nose, sinus infection, pneumonia);
• reakcije na mestu injiciranja (vključno z bolečino, oteklostjo, pordelostjo ali srbenjem); • okužbe dihalnega trakta (vključno s prehladom, izcedkom iz nosu, okužbo sinusov, pljučnico);
Humira therapy should not be continued in patients failing to respond within this time period.
Pri bolnikih, ki se v tem času ne odzovejo, zdravljenja ni priporočljivo nadaljevati.
Adverse Reaction bacterial infections, eye infections, diverticulitis
raztopina za injiciranje (injekcija) bistra, brezbarvna raztopina
Humira 40 mg Weekly
Humira 40 mg vsak teden placebo
Patients had serum samples tested for autoantibodies at multiple time points in rheumatoid arthritis studies I − V. In these trials, 11.9% of patients treated with Humira and 8.1% of placebo and active control − treated patients that had negative baseline anti-nuclear antibody titres reported positive titres at Week 24.
prejemnikov zdravila Humira in 8,1 % prejemnikov placeba in kontrolne učinkovine, ki so imeli izhodiščno negativne titre teh protiteles.
• low blood measurements for platelets
• nizke krvne vrednosti za trombocite
Disease flares at the end of 32weeks a (n/N)
32-tedenskega obdobjaa (n/N)
You should not take Humira with medicines containing the following active substances due to increased risk of serious infection:
Zaradi povečanega tveganja pojava resnih okužb zdravila Humira ne smete jemati skupaj z zdravili, ki vsebujejo naslednje učinkovine: