natgillin/translations-raw huggingface dataset:
Questions and answers on Canazole (clotrimazole cream
Vprašanja in odgovori v zvezi z zdravilom Canazole (klotrimazol krema 1 %)
Ref.: EMEA/528144/2009 EMEA/H/C/535
: EMEA/528144/2009 EMEA/H/C/535
The marketing authorisation was renewed on 13 October 2009.
Dovoljenje za promet je bilo podaljšano 13. oktobra 2009.
A reduced dose is used in children.
Pri otrocih se uporablja zmanjšan odmerek.
It is available as capsules (blue: 25 mg; orange: 50 mg).
Na voljo je v obliki kapsul (modrih: 25 mg; oranžnih: 50 mg).
The usual dose for adults is 50 mg three times a day.
Priporočeni odmerek za odrasle je 50 mg trikrat na dan.
This causes a variety of effects, including liver disease and damage to the nervous system.
To povzroča številne učinke, vključno z boleznimi jeter in poškodbami živčevja.
This results in copper building up in the body, first in the liver, then in other organs such as the eye and the brain.
Posledično se baker kopiči v telesu, najprej v jetrih, zatem pa tudi v drugih organih, kot so oči in možgani.
Wilzin zinc EPAR summary for the public
Wilzin cink Povzetek EPAR za javnost
Other information about Wilzin:
Druge informacije o zdravilu Wilzin:
The main measure of effectiveness was whether patients had adequate control of copper levels.
Glavno merilo učinkovitosti je bilo, ali je pri bolnikih doseženo ustrezno vzdrževanje ravni bakra.
Gastric irritation is usually worst with the first morning dose and disappears after the first few days of treatment.
Draženje želodca je navadno najhujše pri prvem jutranjem odmerku, po prvih nekaj dneh zdravljenja pa izgine.
Over time, the amount of copper in the body falls, improving the symptoms of the disease.
Sčasoma se količina bakra v telesu zmanjša, kar izboljša simptome bolezni.
Wilzin should be taken on an empty stomach, at least one hour before or two to three hours after meals.
Zdravilo Wilzin je treba jemati na prazen želodec, najmanj eno uro pred obrokom ali dve do tri ure njem.
The European Commission granted a marketing authorisation valid throughout the European Union for Wilzin to Orphan Europe SARL on 13 October 2004.
Evropska komisija je dovoljenje za promet z zdravilom Wilzin, veljavno po vsej Evropski uniji, odobrila družbi Orphan Europe SARL dne 13. oktobra 2004.
The main study involved 148 patients who were treated with Wilzin, but did not compare Wilzin with any other treatments.
V glavno študijo je bilo vključenih 148 bolnikov, ki so bili zdravljeni z zdravilom Wilzin, v njej pa zdravila Wilzin niso primerjali z nobenim drugim zdravljenjem.
This protein attaches to copper and prevents it being transferred into the blood.
Ta beljakovina se veže na baker in preprečuje njegov prenos v kri.
Because zinc has been used to treat Wilson's disease for many years, the company presented the results of studies from the published literature.
Ker se cink že dolgo časa uporablja za zdravljenje Wilsonove bolezni, je družba predstavila rezultate študij iz objavljene literature.
The summary of opinion of the Committee for Orphan Medicinal Products for Wilzin is available here.
Povzetek mnenja Odbora za zdravila sirote o zdravilu Wilzin je na voljo tukaj.
What benefit has Wilzin shown during the studies?
Kakšne koristi je zdravilo Wilzin izkazalo med študijami?
In the main study, 91% of the patients evaluated (91 out of 100) had adequate control of their copper levels within the first year of treatment with Wilzin.
V okviru glavne študije je 91 % ovrednotenih bolnikov (91 bolnikov od 100) v prvem letu zdravljenja z zdravilom Wilzin doseglo ustrezno vzdrževanje ravni bakra.
Delaying the first dose to mid-morning or taking the dose with a small amount of food containing protein, such as meat, may help.
Preložitev prvega odmerka na sredino dopoldneva ali jemanje odmerka z malo beljakovinske hrane, npr. mesa, navadno olajša simptome.
Patients who are switching from a ‘chelating agent' (another type of medicine for Wilson's disease) to Wilzin should continue to take the chelating agent for two to three weeks after starting Wilzin, because Wilzin takes some time to start working fully.
Bolniki, ki z jemanja „kelatorjev“ (druge vrste zdravila za Wilsonovo bolezen) prehajajo na zdravilo Wilzin, morajo kelatorje jemati še dva do tri tedne po začetku jemanja zdravila Wilzin, saj je za pričetek popolnega delovanja zdravila Wilzin potreben določen čas.
The Committee for Medicinal products for Human Use (CHMP) noted that Wilson's disease is a fatal disease and the other medicines already being used for the disease can have severe side effects.
Odbor za zdravila za uporabo v humani medicini (CHMP) je ugotovil, da je Wilsonova bolezen smrtna in da imajo zdravila, ki so že v uporabi, hude neželene učinke.
The most common side effects with Wilzin (seen in between 1 and 10 patients in 100) are gastric irritation (irritation of the stomach) and increased blood levels of enzymes (amylase, lipase and alkaline phosphatase).
Najpogostejši neželeni učinki zdravila Wilzin (opaženi pri 1 do 10 bolnikih izmed 100) so draženje želodca in povišane ravni encimov v krvi (amilaze, lipaze in alkalne fosfataze).
In total, data to support the use of Wilzin came from 255 patients with Wilson's disease.
Podatki v podporo uporabi zdravila Wilzin prihajajo skupaj od 255 bolnikov z Wilsonovo boleznijo.
Wilzin has been shown to be effective in reducing the absorption of copper and reducing the amount of copper in the body.
Zdravilo Wilzin se je izkazalo kot učinkovito pri zmanjševanju absorpcije bakra in zmanjševanju količine bakra v telesu.
Wilzin should not be used in people who may be hypersensitive (allergic) to zinc or any of the other ingredients.
Zdravila Wilzin ne smejo uporabljati osebe, ki utegnejo biti preobčutljive za (alergične na) cink ali katero koli drugo sestavino zdravila.
Zinc has been used to treat Wilson's disease since 1958.
Cink se za zdravljenje Wilsonove bolezni uporablja od leta 1958 naprej.
Wilson's disease is a rare inherited disorder where patients lack an enzyme that is needed to eliminate the copper contained in food from the body.
Wilsonova bolezen je redka prirojena napaka, pri kateri bolniki nimajo encima, potrebnega za izločanje bakra, ki se nahaja v hrani, iz telesa.
Because the number of patients with Wilson's disease is low, the disease is considered ‘rare', and Wilzin was designated an ‘orphan medicine' (a medicine used in rare diseases) on 31 July 2001.
Ker je bolnikov z Wilsonovo boleznijo malo, velja ta bolezen za redko, zato je bilo zdravilo Wilzin dne 31. julija 2001 določeno kot „zdravilo sirota“ (zdravilo, ki se uporablja pri redkih boleznih).
It works by stimulating the body to produce a protein called metallothionein in the cells lining the gut.
Zdravilo spodbudi telo, da začne tvoriti beljakovino, imenovano metalotionein, v celicah, ki obkrožajo črevesje.
The Committee recommended that Wilzin be given marketing authorisation.
Odbor je priporočil, da se za zdravilo Wilzin odobri dovoljenje za promet.
What is the risk associated with Wilzin?
Kakšna tveganja so povezana z zdravilom Wilzin?
Wilzin is a medicine that contains the active substance zinc.
Wilzin je zdravilo, ki vsebuje zdravilno učinkovino cink.
Wilzin treatment should be started by a doctor who has experience in the treatment of Wilson's disease.
Zdravljenje z zdravilom Wilzin mora uvesti zdravnik z izkušnjami z zdravljenjem Wilsonove bolezni.
Why has Wilzin been approved?
Zakaj je bilo zdravilo Wilzin odobreno?
For the full list of all side effects reported with Wilzin, see the Package Leaflet.
Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila Wilzin, glejte navodilo za uporabo.
The active substance in Wilzin is the zinc cation (positively charged zinc), which blocks the absorption of copper from the diet.
Zdravilna učinkovina zdravila Wilzin je cinkov kation (pozitivno nabit cink), ki zavira absorpcijo bakra iz hrane.
Therefore, the Committee decided that Wilzin's benefits are greater than its risks for the treatment of Wilson's disease.
Zato je Odbor zaključil, da so koristi zdravila Wilzin za zdravljenje Wilsonove bolezni večje od z njim povezanih tveganj.
The copper is then passed out of the body in the stools.
Baker se nato izloči iz telesa z blatom.
Wilzin is used to treat Wilson's disease.
Zdravilo Wilzin je namenjeno za zdravljenje Wilsonove bolezni.
The maximum dose of Wilzin is 50 mg five times a day.
Najvišji odmerek zdravila Wilzin je 50 mg petkrat na dan. Za več informacij glejte navodilo za uporabo.
What is Wilzin used for?
Za kaj se zdravilo Wilzin uporablja?
How has Wilzin been studied?
Kako je bilo zdravilo Wilzin raziskano?
What is Wilzin?
Kaj je zdravilo Wilzin?
How does Wilzin work?
Kako zdravilo Wilzin deluje?
The full EPAR for Wilzin can be found here.
Celotno evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Wilzin je na voljo tukaj.
How is Wilzin used?
Kako se zdravilo Wilzin uporablja?
Wilzin is a long-term treatment.
Zdravljenje z zdravilom Wilzin traja vse življenje.
- Tell your doctor:
- Povejte zdravniku:
Date of first authorisation: 9 January 2012 Date of latest renewal: 9 September 2016
Datum prve odobritve: 9. januar 2012 Datum zadnjega podaljšanja: 9. september 2016
This combination should be used with caution.
To kombinacijo je treba uporabljati previdno.
The combination was generally well tolerated.
Kombinacijo so na splošno dobro prenašali.
(see section 4.3).
(Glejte poglavje 4.4.)
Risk to the infant cannot be excluded.
Tveganja za novorojenca ne moremo izključiti.
10000 Zagreb, Croatia
10000 Zagreb Hrvaška
Adults and adolescents over 40 kg
Odrasli in mladostniki težji od 40 kg
- If any member of your family (parents, grandparents, brothers or sisters) has died suddenly due to a heart problem or was born with heart problems.
- če je kateri koli član vaše družine (starši, stari starši, bratje ali sestre) nenadoma umrl zaradi težav s srcem ali je bil rojen z okvaro na srcu.
Keep the medicine container with you so that you can easily describe what you have taken.
S seboj imejte embalažo zdravila, da boste zlahka opisali, kaj ste zaužili.
- It is recommended that the tablet be swallowed whole with water.
- Priporočamo, da tableto pogoltnete celo, z vodo.
Some patients have more serious symptoms that may affect mood or the ability to think clearly.
Nekateri bolniki imajo hujše simptome, ki lahko vplivajo na njihovo razpoloženje ali zmožnost jasnega razmišljanja.
It is used by adults, adolescents and children 3 years of age and older.
Uporablja se pri odraslih, mladostnikih in otrocih, starih 3 leta ali več.
Discuss with your doctor the precautions needed to avoid infecting other people.
Posvetujte se z zdravnikom o potrebnih previdnostnih ukrepih, da se izognete okužbi drugih ljudi.
It is important to tell your doctor or pharmacist if you are taking any of the following: - Other medicines used for HIV infection:
Pomembno je, da zdravniku ali farmacevtu poveste, če jemljete kar koli od naštetega: - Druga zdravila, ki se uporabljajo pri okužbi s HIV:
(CYP3A induction - effect on boceprevir) *0-8 hours
(indukcija CYP3A - vpliv na boceprevir) *0-8 ur
It must always be taken in combination with other anti-HIV medicines.
Vedno ga jemljite le v kombinaciji z drugimi zdravili proti HIV.
ATC code: J05AG03
Oznaka ATC: J05AG03
Any inflammatory symptoms should be evaluated and treatment instituted when necessary.
Kakršne koli vnetne simptome je potrebno obravnavati in uvesti zdravljenje, kadar je potrebno.
Typically, such reactions have been observed within the first few weeks or months of initiation of CART.
Take reakcije so značilno opazili v prvih nekaj tednih ali mesecih po uvedbi
Efavirenz is highly bound (approximately 99.5-99.75%) to human plasma proteins, predominantly albumin.
Efavirenz se močno veže (približno 99,5 - 99,75 %) na človeške plazemske beljakovine, predvsem na albumin.
- If your doctor has told you that you have high or low levels of electrolytes such as potassium or magnesium in your blood.
- če vam je zdravnik povedal, da imate visok ali nizek nivo elektrolitov, kot sta kalij ali magnezij, v krvi.
The standard doses of NRTIs given every 12 hours were used in each of these studies.
V vsaki od teh študij so uporabili standardne odmerke NRTI na vsakih 12 ur.
See below and section 5.3.
Glejte v nadaljevanju in poglavje 5.3.
- unexplained feelings of distress not associated with hallucinations, but it may be difficult to think clearly or sensibly - suicide
- nepojasnjeni občutki stiske, ki niso povezani s halucinacijami, lahko pa povzročajo težave pri jasnem ali razumnem razmišljanju - samomor
Study ACTG 364 48 weeks
Študija ACTG 48 tednov
This may stop the medicines from working properly, or may make any side effects worse.
To lahko prepreči pravilno delovanje zdravila ali poslabša neželene učinke.
Substitutions at RT positions 98, 100, 101, 108, 138, 188, 190 or 225 were also observed, but at lower frequencies, and often only in combination with K103N.
Opazili so tudi substitucije na RT na položajih 98, 100, 101, 108, 138, 188, 190 ali 225, vendar redkeje in pogosto le v kombinaciji s K103N.
- If you are allergic to efavirenz or any of the other ingredients of this medicine (listed in section 6).
- če ste alergični na efavirenz ali katero koli od sestavin tega zdravila (navedeno v poglavju 6).
- Medicines used to treat malaria:
- Zdravila za zdravljenje malarije:
Undesirable effects in children were generally similar to those of adult patients.
Pediatrična populacija Neželeni učinki pri otrocih so bili na splošno podobni kakor pri odraslih bolnikih.
It is believed that these symptoms are due to an improvement in the body's immune response, enabling the body to fight infections that may have been present with no obvious symptoms.
da so ti simptomi posledica izboljšanja telesnega imunskega odgovora, ki omogoča telesu, da se brani pred okužbami, ki so bile prej prisotne brez očitnih simptomov.
While effective viral suppression with antiretroviral therapy, has been proven to substantially reduce the risk of sexual transmission, a residual risk cannot be excluded.
Čeprav se je izkazalo, da učinkovita virusna supresija s protiretrovirusno terapijo bistveno zmanjša tveganje spolnega prenosa, preostalega tveganja ni mogoče izključiti.
- The dose for adults is 600 mg once daily.
- Odmerek za odrasle je 600 mg enkrat na dan.
When treating HIV infection, it is not always possible to tell whether some of the unwanted effects are caused by Efavirenz Teva or by other medicines that you are taking at the same time, or by the HIV disease itself.
Pri zdravljenju okužbe s HIV je včasih težko reči, ali se nekateri neželeni učinki pojavijo zaradi zdravila Efavirenz Teva, drugih zdravil, ki jih jemljete sočasno, ali zaradi bolezni HIV same.
- You can still pass on HIV when taking this medicine, although the risk is lowered by effective antiretroviral therapy.
- Kljub jemanju tega zdravila lahko še vedno s HIV okužite druge osebe, čeprav je tveganje zmanjšano z učinkovitim protiretrovirusnim zdravljenjem.
This proportion is approximately 3-fold higher than the non-protein-bound (free) fraction of efavirenz in plasma.
Ta delež je približno 3-krat višji od frakcije efavirenza v plazmi, ki ni vezana na beljakovine (prosta frakcija).
- Medicines used to treat infection with the hepatitis C virus: boceprevir, telaprevir,
- Zdravila za zdravljenje okužbe z virusom hepatitisa C: boceprevir, telaprevir,
Patients should be advised that if they experience symptoms such as severe depression, psychosis or suicidal ideation, they should contact their doctor immediately to assess the possibility that the symptoms may be related to the use of efavirenz, and if so, to determine whether the risks of continued therapy outweigh the benefits (see section 4.8).
Bolnikom je treba svetovati, naj se v primeru pojava simptomov, kot so huda oblika depresije, psihoza ali misel na samomor, nemudoma posvetujejo z zdravnikom, ki bo ocenil, ali so simptomi lahko povezani z jemanjem efavirenza, in odločil, ali je tveganje nadaljevanja zdravljenja z efavirenzem večje od koristi (glejte poglavje 4.8).
Tell your doctor if you notice any of the following side effects: Very common (affects more than 1 user in 10)
Zdravniku povejte, če opazite katerega koli od naslednjih neželenih učinkov: Zelo pogosti (pojavijo se pri več kot 1 od 10 bolnikov) - kožni izpuščaj
No dose adjustment is necessary for rifampicin, including 600 mg.
Prilagoditev odmerka rifampicina, vključno s 600 mg, ni potrebna.
Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucosegalactose malabsorption should not take this medicinal product.
Bolniki z redko dedno intoleranco za galaktozo, odsotnostjo encima laktaze ali malabsorpcijo glukozegalaktoze ne smejo jemati tega zdravila.
Verapamil, felodipine, nifedipine and nicardipine
verapamil, felodipin, nifedipin in nikardipin
If you are pregnant, you should take Efavirenz Teva only if you and your doctor decide it is clearly needed.
Če ste noseči, lahko zdravilo Efavirenz Teva jemljete le, če se z zdravnikom skupaj odločita, da je to nujno potrebno.
Neither aluminium/magnesium hydroxide antacids nor famotidine altered the absorption of efavirenz.
Niti aluminijevi/ magnezijevi hidroksidni antacidi niti famotidin niso spremenili absorpcije efavirenza.
elbasvir/grazoprevir, simeprevir, sofosbuvir/velpatasvir, sofosbuvir/velpatasvir/voxilaprevir, glecaprevir/pibrentasvir.
elbasvir/grazoprevir, simeprevir, sofosbuvir/velpatasvir, sofosbuvir/velpatasvir/voksilaprevir, glekaprevir/pibrentasvir.
These drugs include: - antiarrhythmics of classes IA and III, - neuroleptics, antidepressive agents,
Med taka zdravila sodijo: - antiaritmiki razreda IA in III, - nevroleptiki, antidepresivi,
In addition, your doctor may prescribe a higher dose of Efavirenz Teva.
Poleg tega vam bo zdravnik morda predpisal večji odmerek zdravila Efavirenz Teva.
Your doctor has prescribed Efavirenz Teva for you because you have HIV infection.
Zdravnik vam je predpisal zdravilo Efavirenz Teva, ker ste okuženi z virusom HIV.
Clarithromycin 14-hydroxymetabolite:
klaritromicin 14-hidroksimetabolit:
If you have taken Efavirenz Teva or the combination tablet containing efavirenz, emtricitabine, and tenofovir during your pregnancy, your doctor may request regular blood tests and other diagnostic tests to monitor the development of your child.
Če zdravilo Efavirenz Teva ali kombinirano zdravilo, ki vsebuje efavirenz, emtricitabin in tenofovir jemljete med nosečnostjo, bo zdravnik morda naročil redne krvne preiskave in druge diagnostične teste za spremljanje razvoja otroka.
- Immunosuppressants such as cyclosporine, sirolimus, or tacrolimus (medicines used to prevent organ transplant rejection): when you start or stop taking Efavirenz Teva, your doctor will closely monitor your plasma levels of the immunosuppressant and may need to adjust its dose.
- Imunosupresive, kot so ciklosporin, sirolimus ali takrolimus (zdravila za preprečitev zavrnitve presajenega organa): ko boste začeli ali prenehali jemati zdravilo Efavirenz Teva, bo zdravnik skrbno nadzoroval količino imunosupresiva v plazmi in bo morda moral prilagoditi njegov odmerek.
Efavirenz has a relatively long terminal half-life of at least 52 hours after single doses and 40-55 hours after multiple doses.
Efavirenz ima relativno dolg končni razpolovni čas: vsaj 52 ur po enkratnem odmerku in 40 do 55 ur po večkratnih odmerkih.
Five of these NNRTI-resistant isolates were found to have K103N or a valine-to-isoleucine substitution at position 108 (V108I) in RT. Three of the efavirenz treatment failure isolates tested remained sensitive to efavirenz in cell culture and were also sensitive to nevirapine and delavirdine.
Pri petih od teh na NNRTI rezistentnih izolatov so našli substitucijo K103N ali substitucijo valin-v-izolevcin na položaju 108 (V108I) na RT. Trije od teh testiranih izolatov iz neuspešnega zdravljenja z efavirenzem so ostali občutljivi na efavirenz v celični kulturi in so bili občutljivi tudi na nevirapin in delavirdin.
Since use of two NNRTIs proved not beneficial in terms of efficacy and safety, co-administration of efavirenz and another NNRTI is not recommended.
Ker uporaba dveh zdravil NNRTI ni pokazala koristi glede učinkovitosti in varnosti, sočasne uporabe efavirenza in drugega zdravila NNRTI ne priporočamo.
30 x 1 film-coated tablets.
30 x1 filmsko obložena tableta.
Study 020 showed similar activity in NRTI-experienced patients over 24 weeks.
Študija 020 je pri bolnikih, ki so se že zdravili z NRTI, po 24 tednih pokazala podobno aktivnost.
Efavirenz regimen Control regimen (n=1,008)
bolniki, ki so prejemali efavirenz kontrolna skupina (n = 1.008)
- Medicines used to lower blood fats (also called statins): atorvastatin, pravastatin, simvastatin.
- Zdravila za znižanje maščob v krvi (imenovana tudi statini): atorvastatin, pravastatin, simvastatin.
Sufficient data on the tolerability of efavirenz with low-dose ritonavir (100 mg, once or twice daily) are not available.
Zadostnih podatkov o prenašanju efavirenza z majhnimi odmerki ritonavirja (100 mg, enkrat ali dvakrat na dan) ni na voljo.
Taking these medicines with Efavirenz Teva could create the potential for serious and/or life-threatening side effects or stop Efavirenz Teva from working properly.
Jemanje teh zdravil skupaj z zdravilom Efavirenz Teva bi lahko povzročilo resne in/ali življenjsko nevarne neželene učinke ali preprečilo pravilno delovanje zdravila Efavirenz Teva.
The potency of efavirenz in cell culture against viral variants with amino acid substitutions at positions 48, 108, 179, 181 or 236 in RT or variants with amino acid substitutions in the protease was similar to that observed against wild-type viral strains.
Učinkovitost efavirenza v celičnih kulturah proti virusnim različicam z aminokislinskimi substitucijami na mestih 48, 108, 179, 181 ali 236 na RT ali različicam z aminokislinskimi substitucijami na proteazi je bila podobna njegovi učinkovitosti proti divjim tipom virusnih sevov.
Efavirenz: no clinically significant interaction.
efavirenz: Ni klinično pomembnih interakcij.
- Diltiazem or similar medicines (called calcium channel blockers which are medicines typically used for high blood pressure or heart problems): when you start taking Efavirenz
- Diltiazem ali podobna zdravila (imenovana zaviralci kalcijevih kanalčkov, zdravila, ki se običajno uporabljajo za zvišan krvni tlak ali težave s srcem): ko boste začeli jemati zdravilo
↓velpatasvir ↓voxilaprevir
↓velpatasvir ↓voksilaprevir
Cross-resistance profiles for efavirenz, nevirapine and delavirdine in cell culture demonstrated that the K103N substitution confers loss of susceptibility to all three NNRTIs.
Profili navzkrižne rezistence na efavirenz, nevirapin in delavirdin v celičnih kulturah so pokazali, da substitucija K103N povzroči izgubo občutljivosti na vse tri NNRTI.
- Efavirenz Teva must be taken with other medicines that act against the HIV virus.
- Efavirenz Teva je treba jemati skupaj z drugimi zdravili, ki delujejo proti virusu HIV.
Efficacy results for studies ACTG 364 and 020 are found in Table 3.
Rezultate učinkovitosti v študijah ACTG 364 in 020 prikazuje preglednica 4.
The free concentration of efavirenz required for 90 to 95% inhibition of wild type or zidovudine-resistant laboratory and clinical isolates in vitro ranged from 0.46 to 6.8 nM in lymphoblastoid cell lines, peripheral blood mononuclear cells (PBMCs) and macrophage/monocyte cultures.
Koncentracija prostega efavirenza, potrebna za 90 % do 95 % in vitro inhibicijo laboratorijskih in kliničnih izolatov divjega tipa ali tistih, ki so rezistentni na zidovudin, je bila v območju od 0,46 do 6,8 nM, in sicer v limfoblastoidnih celičnih linijah, perifernih krvnih enojedrnih celicah (PBMC) in v kulturah makrofagov/monocitov.
Lipid disorders should be managed as clinically appropriate
Motnje lipidov je treba obravnavati klinično ustrezno.
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Če vam je zdravnik povedal, da ne prenašate nekaterih sladkorjev, se, preden začnete jemati to zdravilo, posvetujte z njim.
Tests may show: - increased cholesterol in the blood
Testi lahko pokažejo: - povišane vrednosti holesterola v krvi