natgillin/translations-raw huggingface dataset:
Xaluprine may be taken with food or on an empty stomach.
Zdravilo Xaluprine se lahko vzame skupaj s hrano ali na tešče.
To decrease the risk of exposure disposable gloves should be used when handling Xaluprine.
Za zmanjšanje tveganja izpostavljenosti pri uporabi zdravila Xaluprine vedno uporabljajte rokavice za enkratno uporabo.
Volume (ml)
Prostorni na (ml)
Xaluprine may be taken with food or on an empty stomach, but patients should standardise the method of administration.
Zdravilo Xaluprine se lahko jemlje s hrano ali na tešče, bolniki pa naj način uporabe poenotijo.
Other side effects (the frequency is unknown) - a rare type of cancer (hepatosplenic T-cell lymphoma), (see section 2, Warnings and
- redka vrsta raka (jetrnovranični T-celični limfom) (glejte poglavje 2, Opozorila in previdnostni ukrepi)
Common (affects less than 1 in 10 people) - feeling or being sick (nausea or vomiting) - liver damage - this may show up in blood tests - a drop in red blood cells which may make you tired, weak or breathless (called anaemia) - loss of appetite - diarrhoea - inflammation of the mouth (stomatitis)
Zelo pogosti (pojavijo se pri več kot 1 od 10 bolnikov) - zmanjšanje števila belih krvnih celic in trombocitov (lahko se pokaže pri krvnih preiskavah) Pogosti (pojavijo se pri manj kot 1 od 10 bolnikov) - občutek slabosti ali slabost (navzea ali bruhanje)
Patients with inherited mutated NUDT15 gene are at increased risk for severe 6-mercaptopurine toxicity, such as early leukopenia and alopecia, from conventional doses of thiopurine therapy.
Bolniki z varianto NUDT15 Bolniki s podedovanim mutiranim genom NUDT15 so ob konvencionalnih odmerkih tiopurina izpostavljeni povečanemu tveganju za hudo toksičnost zaradi 6-merkaptopurina, kot sta zgodnja levkopenija in alopecija.
Do not stop taking your medicine unless your doctor tells you to or you may get a relapse of your condition.
Če ste prenehali jemati zdravilo Xaluprine Ne prenehajte jemati zdravila, razen če vam je tako naročil zdravnik, saj se lahko bolezen ponovi.
Do not breast-feed while taking Xaluprine.
Med jemanjem zdravila Xaluprine ne smete dojiti.
- Your doctor may sometimes change your dose of Xaluprine as a result of these tests.
- Na podlagi izvidov teh testov lahko zdravnik občasno spremeni odmerek zdravila Xaluprine.
Since 6-mercaptopurine pharmacokinetics has not been formally studied in hepatic impairment, no specific dose recommendations can be given.
Okvarjeno delovanje jeter Ker farmakokinetika 6-merkaptopurina pri okvarjenem delovanju jeter ni bila uradno raziskana, ni mogoče priporočiti določenega odmerka.
Effects of mercaptopurine on other medicinal products Concomitant administration of yellow fever vaccine is contraindicated, due to the risk of fatal disease in immunocompromised patients (see section 4.3)
Sočasna uporaba s cepivom proti rumeni mrzlici je kontraindicirana zaradi tveganja za smrtno bolezen pri bolnikih z oslabljenim imunskim sistemom (glejte poglavje 4.3).
Xaluprine 20 mg/ml oral suspension mercaptopurine
Xaluprine 20 mg/ml peroralna suspenzija merkaptopurin
Anyone handling Xaluprine should wash their hands before and after administering a dose.
Pred uporabo odmerka zdravila Xaluprine in po njem je potrebno umivanje rok.
The other ingredients are xanthan gum, aspartame (E951), concentrated raspberry juice, sucrose, sodium methyl parahydroxybenzoate (E219), sodium ethyl parahydroxybenzoate (E215), potassium sorbate (E202), sodium hydroxide and purified water (see section 2 Xaluprine contains aspartame, sodium methyl parahydroxybenzoate (E219), sodium ethyl parahydroxybenzoate (E215) and sucrose).
Druge sestavine so ksantanski gumi, aspartam (E951), koncentriran malinov sok, saharoza, natrijev metilparahidroksibenzoat (E 219), natrijev etilparahidroksibenzoat (E 215), kalijev sorbat (E 202), natrijev hidroksid in prečiščena voda (glejte poglavje 2 za dodatne informacije o aspartamu, natrijevem metilparahidroksibenzoatu (E 219), natrijevem etilparahidroksibenzoatu (E 215) in saharozi).
Contents of the pack and other information
Shranjevanje zdravila Xaluprine Vsebina pakiranja in dodatne informacije
Therefore, Xaluprine may be taken with food or on an empty stomach, but patients should standardise the method of administration.
Zato se lahko zdravilo Xaluprine jemlje s hrano ali na tešče, bolniki pa naj način uporabe poenotijo.
Xaluprine is cytotoxic.
Zdravilo Xaluprin je citotoksično.
o A combination of multiple immunosuppressants, given concomitantly increases the risk of disorders of the lymph system due to a viral infection (Epstein-Barr virus (EBV)-associated lymphoproliferative disorders).
o Kombinacija več imunosupresivnih zdravil, ki se dajejo sočasno, poveča tveganje za bolezni limfnega sistema zaradi virusne okužbe (limfoproliferativne bolezni,
Oral suspension.
peroralna suspenzija
Discard 56 days after first opening.
56 dni po prvem odpiranju zdravilo zavrzite.
The bioavailability of oral 6-mercaptopurine shows considerable inter-individual variability, which probably results from its first-pass metabolism.
Biološka uporabnost peroralnega 6-merkaptopurina kaže pomembno variabilnost med posamezniki,
Talk to your doctor, pharmacist or nurse before taking Xaluprine if: - you have been vaccinated with yellow fever vaccine - you have kidney or liver problems, as your doctor will need to check that they are working properly.
- ste bili cepljeni s cepivom proti rumeni mrzlici; - imate težave z ledvicami ali jetri - v tem primeru bo moral zdravnik preveriti, ali pravilno delujejo; - imate bolezen, pri kateri vaše telo proizvaja premalo encima TPMT (tiopurin metiltransferaza)
STATEMENT OF ACTIVE SUBSTANCE(S) One ml of suspension contains 20 mg mercaptopurine (as monohydrate).
En ml suspenzije vsebuje 20 mg merkaptopurina (v obliki monohidrata).
More frequent monitoring may be advisable in those with pre-existing liver disease or receiving other potentially hepatotoxic therapy.
Pri bolnikih z že obstoječo boleznijo jeter ali bolnikih, ki prejemajo druga potencialno hepatotoksična zdravila, se priporoča pogostejše spremljanje delovanja jeter.
Each pack contains one bottle, a bottle adaptor and two dosing syringes (a purple syringe graduated to 1 ml and a white syringe graduated to 5 ml).
V vsakem pakiranju je ena steklenica, nastavek za steklenico in dve brizgi za odmerjanje (vijolična brizga z merilno skalo do 1 ml in bela brizga z merilno skalo do 5 ml).
Having vaccines while you are taking Xaluprine If you are going to have a vaccination it is important to speak to your doctor or nurse before you have it. Vaccination with live vaccines (like polio, measles, mumps and rubella) is not recommended, as these vaccines may give you an infection if you have them whilst you are taking Xaluprine.
Cepljenje z živimi cepivi (npr. proti otroški paralizi, ošpicam, mumpsu in rdečkam) ni priporočljivo, saj lahko ta cepiva pri sočasni uporabi z zdravilom Xaluprine povzročajo okužbe.
- Allergic reaction, the signs may include: o skin rashes o high temperature o joint pain o swollen face
Alergijske reakcije, ki imajo lahko naslednje znake: - kožni izpuščaj
* In patients with inflammatory bowel disease (IBD), an unlicensed indication.
Prehodna oligospermija *Pri bolnikih z vnetno črevesno boleznijo, ki je indikacija brez odobritve.
Each pack contains one bottle, an HDPE bottle adaptor and 2 polyethylene dosing syringes (a purple syringe graduated to 1 ml and a white syringe graduated to 5 ml).
V vsakem pakiranju je ena steklenica, nastavek HDPE za steklenico in 2 polietilenski brizgi za odmerjanje (vijolična brizga z merilno skalo do 1 ml in bela brizga z merilno skalo do 5 ml).
Put on disposable hand gloves before handling Xaluprine.
Pred ravnanjem z zdravilom Xaluprine si nadenite rokavice za enkratno uporabo.
The expiry date refers to the last day of that month, - Do not store above 25°C.
Rok uporabnosti zdravila se izteče na zadnji dan navedenega meseca.
- other cytotoxic medicines (chemotherapy) - when used with Xaluprine there is a greater chance of side effects, such as anaemia - allopurinol or febuxostat (used to treat gout) - oral anticoagulants (used to thin the blood) - olsalazine or mesalazine (used for a bowel disorder called ulcerative colitis) - sulfasalazine (used for rheumatoid arthritis or ulcerative colitis).
- peroralne antikoagulante (uporabljajo se za redčenje krvi); - olsalazin ali mesalazin (uporablja se pri bolezni črevesja, imenovani ulcerozni kolitis)
What Xaluprine looks like and contents of the pack Xaluprine is a pink to brown oral suspension.
Zdravilo Xaluprine je rožnata do rjava peroralna suspenzija.
Xaluprine is for oral use and requires redispersing (by shaking vigorously at least for 30 seconds) prior to dosing.
Zdravilo Xaluprine je namenjeno peroralni uporabi in se mora pred odmerjanjem redispergirati
Transient profound oligospermia has been reported following exposure to 6-mercaptopurine in combination with corticosteroids.
Po izpostavljenosti 6-merkaptopurinu v kombinaciji s kortikosteroidi so poročali o prehodni močni oligospermiji.
Your doctor or pharmacist will advise which syringe to use depending on the dose that has been prescribed.
Glede na odmerek, ki vam je bil predpisan, vam bo zdravnik ali farmacevt svetoval, katero brizgo morate uporabiti.
Also contains: sodium methyl parahydroxybenzoate (E219), sodium ethyl parahydroxybenzoate (E215), potassium sorbate (E202), sodium hydroxide, aspartame (E951) and sucrose.
Vsebuje tudi: natrijev metilparahidroksibenzoat (E 219), natrijev etilparahidroksibenzoat (E 215), kalijev sorbat (E 202), natrijev hidroksid, aspartam (E951) in saharozo.
In a comparative bioavailability study in healthy adult volunteers (n=60), 50mg of Xaluprine oral suspension was demonstrated to be bioequivalent to the reference 50mg tablet for AUC, but not Cmax.
V primerjalni študiji biološke uporabnosti pri odraslih prostovoljcih (n = 60) se je pokazalo, da je
Monitoring of the INR (International Normalised Ratio) value is recommended during concomitant administration with oral anticoagulants.
Med sočasno uporabo s peroralnimi antikoagulanti se priporoča spremljanje vrednosti INR
Shake the bottle vigorously for at least 30 seconds to ensure the medicine is well mixed (figure 1).
Steklenico pred uporabo močno pretresajte vsaj 30 sekund, da se zdravilo dobro premeša
EXPIRY DATE
Datum odpiranja
Xaluprine contains aspartame, sodium methyl parahydroxybenzoate (E219), sodium ethyl parahydroxybenzoate (E215) and sucrose
Zdravilo Xaluprine vsebuje aspartam, natrijev metilparahidroksibenzoat (E 219), natrijev etilparahidroksibenzoat (E 215) in saharoza
4.4 Special warnings and precautions for use
4.4 Posebna opozorila in previdnostni ukrepi Citotoksičnost in hematološko spremljanje
NAME OF THE MEDICINAL PRODUCT Xaluprine 20 mg/ml oral suspension mercaptopurine
Navodilo za uporabo Xaluprine 20 mg/ml peroralna suspenzija merkaptopurin
100 ml.
peroralna suspenzija 100 ml
Let the syringe dry completely before you use that syringe again for dosing.
Brizga naj se pred naslednjo uporabo popolnoma posuši.
Multiple congenital abnormalities have been reported following maternal 6-mercatopurine treatment in combination with other chemotherapy agents.
Pri materah, ki so se zdravile s 6-merkaptopurinom v kombinaciji z drugimi kemoterapevtiki, so poročali o več prirojenih nepravilnostih.
If you are receiving immunosuppressive therapy, taking Xaluprine could put you at greater risk of:
Če prejemate imunosupresivno terapijo, se lahko zaradi jemanja zdravila Xaluprine poveča tveganje za: - pojav tumorjev, tudi za pojav kožnega raka.
Immunisation using a live organism vaccine has the potential to cause infection in immunocompromised hosts.
Pri bolnikih z oslabljenim imunskim sistemom lahko po cepljenju z živim cepivom pride do okužbe.
3rd Floor, Ulysses House
Nova Laboratories Ireland Limited 3rd Floor, Ulysses House
Amber type III glass bottle with tamper evident child-resistant closure (HDPE with expanded polyethylene liner) containing 100 ml of oral suspension.
Rjava steklenica, ki vsebuje 100 ml peroralne suspenzije, iz stekla tipa III z zaporko, ki je varna za otroke in omogoča evidentiranje odpiranja (HDPE z razširjenim polietilenskim vložkom).
There is low entry of 6-mercaptopurine into the cerebrospinal fluid.
Vnos 6-merkaptopurina v likvor je majhen.
Put the cap back on the bottle with the adaptor left in place.
Nastavek pustite na steklenici in jo zaprite z zaporko.
- anti-epileptic medicines such as phenytoin, carbamazepine.
- sulfasalazin (uporablja se pri revmatoidnem artritisu ali ulceroznem kolitisu); - zdravila proti epilepsiji, kot sta fenitoin in karbamazepin.
- Keep this medicine out of the sight and reach of children, preferably in a locked cupboard.
Shranjevanje zdravila Xaluprine - Zdravilo shranjujte nedosegljivo otrokom, po možnosti v zaklenjeni omari.
Reliable contraception must be used to avoid pregnancy whilst you or your partner are taking Xaluprine.
Med jemanjem zdravila Xaluprine morate vi in vaš partner uporabljati zanesljivo kontracepcijo za preprečitev zanositve.
Bone marrow suppression is reversible if 6-mercaptopurine is withdrawn early enough..
Supresija kostnega mozga je reverzibilna, če se zdravljenje s 6-merkaptopurinom pravočasno prekine.
Ask your doctor, pharmacist or midwife for advice.
Posvetujte se z zdravnikom, farmacevtom ali babico.
6-mercaptopurine is also subject to S-methylation by the enzyme thiopurine S-methyltransferase (TPMT), yielding methylmercaptopurine, which is inactive.
S-metiltransferaza (TPMT), pri čemer se tvori metilmerkaptopurin, ki pa je neaktiven.
Xanthine oxidase is the main catabolic enzyme and it converts the 6-mercaptopurine into the inactive metabolite, 6-thiouric acid.
Ksantin-oksidaza je glavni katabolni encim in pretvarja
Reproductive system and breast disorders
Motnje reprodukcije in dojk Redki
BSA (m2) Dose (mg)
Odmer ek (mg)
Bone marrow suppression; leucopenia and thrombocytopenia
Supresija kostnega mozga, levkopenija in trombocitopenija
Ask your doctor if you would like more explanation about this disease.
Če želite podrobnejšo razlago o bolezni, se pogovorite z zdravnikom.
- Any unexpected bruising or bleeding, as this could mean that too few blood cells of a particular type are being produced
Kakršne koli nepričakovane modrice ali krvavitve, ki bi lahko pomenile, da se ne tvori zadostno število določene vrste krvnih celic Nenadno slabo počutje (čeprav imate normalno telesno temperaturo), bolečine v trebuhu in slabost,
1 ml and 5 ml dosing syringes.
peroralna suspenzija 100 ml steklenica nastavek za steklenico 1 ml in 5 ml brizga za odmerjanje
Renal impairment
Edem obraza
Xaluprine contact with skin or mucous membrane must be avoided.
Izogibajte se stiku zdravila Xaluprine s kožo ali sluznico.
NAME OF THE MEDICINAL PRODUCT Xaluprine 20 mg/ml oral suspension
Xaluprine 20 mg/ml peroralna suspenzija
Also other xanthine oxidase inhibitors, such as febuxostat, may decrease the metabolism of mercaptopurine and concomitant administration is not recommended as data are insufficient to determine an adequate dose reduction.
lahko upočasnijo presnavljanje merkaptopurina, in kadar razpoložljivi podatki ne omogočajo določitve ustreznega zmanjšanja odmerka, se odsvetuje sočasna uporaba.
Vaccinations with other live organism vaccines are not recommended in immunocompromised individuals (see section 4.4).
Cepljenja z drugimi živimi cepivi pri osebah z oslabljenim imunskim sistemom niso priporočljiva
Sodium methyl parahydroxybenzoate (E219) Sodium ethyl parahydroxybenzoate (E215) Potassium sorbate (E202) Sodium hydroxide
FARMACEVTSKI PODATKI 6.1 Seznam pomožnih snovi ksantanski gumi aspartam (E951) koncentriran malinov sok saharoza natrijev metilparahidroksibenzoat (E 219) natrijev etilparahidroksibenzoat (E 215) kalijev sorbat (E 202) natrijev hidroksid prečiščena voda 6.2 Inkompatibilnosti
Cases of neutropenic sepsis have been reported in patients receiving 6-mercaptopurine for ALL.
Pri bolnikih z ALL, ki so prejemali 6-merkaptopurin, so poročali o primerih nevtropenične sepse.
Rare (affects less than 1 in 1,000 people) - hair loss - in men: temporary low sperm count - swollen face - various types of cancers including blood, lymph and skin cancers
- različne vrste raka, vključno s krvnim, limfnim in kožnim rakom Zelo redki (pojavijo se pri manj kot 1 od 10 000 bolnikov)
The risk of overdose is also increased when xanthine oxidase inhibitors is being given concomitantly with 6-mercaptopurine (see section 4.5).
Tveganje za preveliko odmerjanje je povečano tudi pri sočasni uporabi zaviralcev ksantin-oksidaze in
Transient oligospermia
Nekroza jeter
You should use this one if the total amount you have to take is more than 1 ml (each graduation of 0.2 ml contains 4 mg of mercaptopurine).
(vsaka merilna oznaka 0,2 ml pomeni 4 mg merkaptopurina).
Additional side effects in children Low blood sugar (hypoglycaemia) - the frequency is unknown.
- razjede v črevesju Drugi neželeni učinki (z neznano pogostostjo)
Uncommon (affects less than 1 in 100 people) - mouth ulcers - inflamed pancreas - joint pain - skin rash - fever - permanent damage to the liver (hepatic necrosis)
- povišana telesna temperatura - trajne poškodbe jeter (nekroza jeter)
How to store Xaluprine
Cepljenje med jemanjem zdravila Xaluprine
32 mg Dispersible Tablet blister (alu/alu)
32 mg Rozpustná tableta peroralna uporaba
Packaging
Velikost pakiranja
● not known (frequency cannot be estimated from the available data)
• ni znano (pogostnosti ni mogoče oceniti na podlagi podatkov, ki so na voljo).
MARKETING AUTHORISATION NUMBER(S) EU/1/09/548/001 - 007
ŠTEVILKA (ŠTEVILKE) DOVOLJENJA (DOVOLJENJ) ZA PROMET EU/1/09/548/001 - 007
It also contains hydrogenated castor oil.
Vsebuje tudi hidrogenirano ricinusovo olje.
Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu/
Podrobne informacije o zdravilu so objavljene na spletni strani Evropske agencije za zdravila (EMA): http://www.ema.europa.eu/.
Children and adolescents Clopidogrel Acino Pharma GmbH is not intended for use in children or adolescents.
Otroci in mladostniki Zdravilo Klopidogrel Acino Pharma GmbH ni namenjeno za uporabo pri otrocih ali mladostnikih.
Excipients: each film-coated tablet contains 3.80 mg of hydrogenated castor oil.
Pomožne snovi: vsaka filmsko obložena tableta vsebuje 3,80 mg hidrogeniranega ricinusovega olja.
-Very rare side effects:
- Redki neželeni učinki:
If a dose is missed: - Within less than 12 hours after regular scheduled time: patients should take the dose immediately and then take the next dose at the regular scheduled time.
Če bolnik izpusti odmerek: - če je zamuda manj kot 12 ur po pravem času: bolnik naj odmerek vzame takoj, potem pa - če je zamuda več kot 12 ur: bolnik naj naslednji odmerek vzame ob pravem času;
Do not use Clopidogrel Acino Pharma GmbH if you notice any visible sign of damage of blister or film-coated tablets.
Ne uporabljajte zdravila Klopidogrel Acino Pharma GmbH, če ste opazili vidne znake poškodovanja pretisnega omota ali filmsko obloženih tablet.
If you forget to take Clopidogrel Acino Pharma GmbH If you forget to take a dose of Clopidogrel Acino Pharma GmbH, but remember within 12 hours of your usual time, take your tablet straight away and then take your next tablet at the usual time.
Če ste pozabili vzeti zdravilo Klopidogrel Acino Pharma GmbH Če pozabite vzeti odmerek zdravila Klopidogrel Acino Pharma GmbH in se nanj spomnite do 12 ur po ustaljenem času, takoj vzemite tableto in nato vzemite naslednjo tableto spet ob ustaljenem času jemanja.
• Paediatric population Clopidogrel should not be used in children because of efficacy concerns (see section 5.1).
• Pediatrična populacija Klopidogrel naj se pri otrocih ne uporablja iz razlogov, ki zadevajo učinkovitost (glejte
Some other medicines may influence the use of Clopidogrel Acino Pharma GmbH or vice versa.
Nekatera druga zdravila lahko vplivajo na uporabo zdravila Klopidogrel Acino Pharma GmbH in obratno.
If you take more Clopidogrel Acino Pharma GmbH than you should Contact your doctor or the nearest hospital emergency department because of the increased risk of bleeding.
Če ste vzeli večji odmerek zdravila Klopidogrel Acino Pharma GmbH, kot bi smeli Zaradi povečanega tveganja krvavitve se posvetujte s svojim zdravnikom ali oddelkom najbližje bolnišnične nujne zdravniške pomoči.
If you think any of these apply to you, or if you are in any doubt at all, consult your doctor before taking Clopidogrel Acino Pharma GmbH.
Če menite, da se karkoli od navedenega nanaša na vas, ali če ste kakorkoli v dvomih, se posvetujte s svojim zdravnikom, preden boste vzeli Klopidogrel Acino Pharma GmbH.
The usual dose is one 75 mg tablet of Clopidogrel Acino Pharma GmbH per day to be taken orally with or without food, and at the same time each day.
Običajni odmerek je ena 75-mg tableta zdravila Klopidogrel Acino Pharma GmbH na dan, ki jo lahko vzamete s hrano ali brez nje; odmerek morate jemati vsak dan ob istem času.
• You should also tell your doctor immediately if you develop a medical condition (also known as Thrombotic Thrombocytopenic Purpura or TTP) that includes fever and bruising under the skin that may appear as red pinpoint dots, with or without unexplained extreme tiredness, confusion, yellowing of the skin or eyes (jaundice) (see section 4 ‘POSSIBLE SIDE EFFECTS').
• morate takoj povedati zdravniku, če razvijete bolezensko stanje (znano tudi kot trombotična trombocitopenična purpura ali TTP) z zvišano telesno temperaturo in modricami pod kožo, ki se lahko pojavijo kot drobne rdeče pike, z ali brez nerazložljive hude utrujenosti, zmedenosti, porumenele kože ali oči (zlatenica) (glejte poglavje 4
SPECIAL STORAGE CONDITIONS Store in the original blister in order to protect from moisture.
POSEBNA NAVODILA ZA SHRANJEVANJE Shranjujte v originalnem pretisnem omotu za zagotovitev zaščite pred vlago.
If you are pregnant or suspect that you are pregnant, you should tell your doctor or your pharmacist before taking Clopidogrel Acino Pharma GmbH.
Če ste noseči ali mislite, da ste noseči, morate o tem obvestiti svojega zdravnika ali farmacevta, preden vzamete zdravilo Klopidogrel Acino Pharma GmbH.
Clopidogrel Acino Pharma GmbH is taken to prevent blood clots (thrombi) forming in hardened blood vessels (arteries), a process known as atherothrombosis, which can lead to atherothrombotic events (such as stroke, heart attack, or death).
Zdravilo Klopidogrel Acino Pharma GmbH se jemlje za preprečevanje nastanka krvnih strdkov (trombov) v otrdelih krvnih žilah (arterijah), proces je znan kot aterotromboza in lahko vodi do aterotrombotičnih dogodkov (kot so kap, srčni napad ali smrt).
If you become pregnant while taking Clopidogrel Acino Pharma GmbH, consult your doctor immediately as it is recommended not to take clopidogrel while you are pregnant.
Če med zdravljenjem z zdravilom Klopidogrel Acino Pharma GmbH zanosite, se takoj posvetujte s svojim zdravnikom, saj jemanje klopidogrela med nosečnostjo ni priporočljivo.
Furthermore, the pharmacodynamic activity of clopidogrel was not significantly influenced by the coadministration of phenobarbital, or oestrogen.
Poleg tega na farmakodinamično aktivnost klopidogrela ni pomembno vplivala sočasna uporaba fenobarbitala ali estrogena.
Driving and using machines Clopidogrel Acino Pharma GmbH is unlikely to affect your ability to drive or to use machines.
Vpliv na sposobnost upravljanja vozil in strojev Ni verjetno, da bi zdravilo Klopidogrel Acino Pharma GmbH vplivalo na vašo sposobnost za vožnjo ali upravljanje strojev.
Like all medicines, Clopidogrel Acino Pharma GmbH can cause side effects, although not everybody gets them.
Kot vsa zdravila ima lahko tudi zdravilo Klopidogrel Acino Pharma GmbH neželene učinke, ki pa se ne pojavijo pri vseh bolnikih.
If you stop taking Clopidogrel Acino Pharma GmbH Do not stop the treatment unless your doctor tells you so.
Če ste prenehali jemati zdravilo Klopidogrel Acino Pharma GmbH Ne prekinite zdravljenja razen, če tako odloči zdravnik.
Clopidogrel is indicated in adults for the prevention of atherothrombotic events in:
4.1 Terapevtske indikacije Klopidogrel je indiciran pri odraslih za preprečevanje aterotrombotičnih dogodkov pri: