natgillin/translations-raw huggingface dataset:
Patient frequencies are defined as: very common ≥1/10; common ≥1/100 to <1/10; uncommon ≥1/1,000 to <1/100; rare: ≥1/10,000 to <1/1,000; very rare: <1/10,000 and not known (cannot be estimated from the available data).
Pogostnosti pri bolnikih so opredeljene takole: zelo pogosti ≥ 1/10, pogosti ≥ 1/100 do < 1/10, občasni ≥ 1/1.000 do < 1/100, redki: ≥ 1/10.000 do < 1/1.000, zelo redki: < 1/10.000 in neznana pogostnost (pogostnosti iz razpoložljivih podatkov ni mogoče oceniti).
You may give both injections in the same body area (for example, your stomach area), but you should not give the injections very close together.
Obe injekciji lahko daste v isti predel telesa (npr. v predel trebuha), vendar pa ju ne smete dati zelo blizu skupaj.
Use Eperzan only if it is a clear yellow solution and contains no particles.
Zdravilo Eperzan uporabite le, če je bistra, rumena raztopina, ki ne vsebuje delcev.
Eperzan that has been frozen must not be used.
Zdravila Eperzan, ki je zamrznilo, ne smete uporabiti.
Patients should be informed of the characteristic symptom of acute pancreatitis.
Bolnike je treba seznaniti z značilnim simptomom akutnega pankreatitisa.
What if I do not attach the needle as instructed?
Kaj, če igle ne namestim po navodilih?
• if you have a serious problem with emptying your stomach (gastroparesis) or if you have severe bowel disease (severe gastrointestinal disease).
• če imate resne težave s praznjenjem želodca (gastroparezo) ali imate hudo bolezen prebavil (hudo gastrointestinalno bolezen).
If possible show them the pack, or this leaflet.
Če je mogoče, jim pokažite pakiranje zdravila ali to navodilo.
What Eperzan is and what it is used for 2.
Kaj je zdravilo Eperzan in za kaj ga uporabljamo 2.
Since the relative stress of lactation energy demands is much lower in humans than mice and humans have large energy reserves, the mortalities observed in lactating mice are considered not relevant to humans.
Ker je relativni stres energijskih potreb med obdobjem dojenja pri človeku veliko manjši kot pri miših in ker so energijske rezerve pri človeku velike, je umrljivost, opažena pri doječih miših, ocenjena kot nepomembna za človeka.
A decision should be made whether to discontinue breast-feeding or to discontinue therapy, taking into account the benefit of breast-feeding for the child and the benefit of therapy for the mother.
Odločiti se je treba za prenehanje dojenja ali za prenehanje zdravljenja, upoštevaje koristi dojenja za otroka in koristi zdravljenja za žensko.
Keep twisting until you see [3] in the window.
Nadaljujte s sukanjem, dokler v okencu ne vidite [3].
This can make it difficult to concentrate and make you dizzy or sleepy.
Zaradi tega se lahko težko zberete, ste omotični ali zaspani.
Complete dissolution for the 50 mg pen usually occurs within 7 minutes but may take up to 10 minutes.
Popolna raztopitev je s 50-mg peresnikom po navadi dosežena v 7 minutah, a lahko traja do 10 minut.
Do not use the pen if the number ‘1' is not showing.
Ne uporabite peresnika, če ni prikazana številka "1".
Each pen injector should be used by one person only and is for single use.
Vsak injekcijski peresnik sme uporabiti le ena oseba in je namenjen za enkratno uporabo.
† The numbers on the clear cartridge represent stages of preparation for your medicine.
† Številke na prozornem vložku pomenijo stopnje priprave vašega zdravila.
The cup, timer and container are not provided in the pack.
Posodica, štoparica in vsebnik niso priloženi v pakiranju.
It must not be administered intravenously or intramuscularly.
Ne sme se ga uporabljati intravensko ali intramuskularno.
The pancreas changes were not associated with histomorphologic abnormalities or evidence of increased proliferation.
Pankreatičnih sprememb niso spremljale histomorfološke nepravilnosti ali znaki povečane proliferacije.
Seeing small air bubbles remaining is normal and you can still use the pen.
Nekaj preostalih majhnih zračnih mehurčkov je normalno in peresnik lahko kljub temu uporabite.
Do not use this medicine after the expiry date which is stated on the pen and the carton after ‘EXP'.
Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na peresniku in škatli poleg oznake "EXP".
Glaxo Operations UK Limited (Trading as Glaxo Wellcome Operations) Harmire Road
Glaxo Operations UK Limited (posluje kot Glaxo Wellcome Operations) Harmire Road
A pen cannot be re-used.
Peresnika ni mogoče ponovno uporabiti.
Simvastatin AUC was decreased by 40% and simvastatin Cmax was increased by 18%.
AUC simvastatina se je zmanjšala za 40 %, Cmax simvastatina pa se je povečala za 18 %.
Inspect, and continue to swirl the pen until all the powder is dissolved.
Raztopino preglejte in nadaljujte z vrtenjem peresnika, dokler se ves prašek ne raztopi.
This will help mix the medicine.
To bo pomagalo premešati zdravilo.
Each pen is used to deliver one dose.
Vsak peresnik je namenjen za dajanje enega odmerka.
What you need to know before you take Eperzan 3.
Kaj morate vedeti, preden boste vzeli zdravilo Eperzan 3.
7a Choose your injection site (Figure P).
7a Izberite mesto za injiciranje (Slika P).
What if I leave my pen with the needle attached (Step 5), and then come back to finish the next step much later?
Kaj, če pustim peresnik z nameščeno iglo (5. korak) in naslednji korak dokončam šele veliko pozneje?
These are rare in people taking Eperzan (may affect up to 1 in 1000 people).
Te so redke pri ljudeh, ki prejemajo zdravilo Eperzan (pojavijo se lahko pri do 1 od 1.000 bolnikov).
Figure A * Injection Button is inside the pen until the pen is ready for injection.
Slika A * Gumb za injiciranje je znotraj peresnika, dokler peresnik ni pripravljen za injiciranje.
Eperzan should not be used during pregnancy, and is not recommended in women of childbearing potential not using effective contraception.
Zdravila Eperzan se ne sme uporabljati med nosečnostjo ter ni priporočljivo za ženske v rodni dobi, ki ne uporabljajo učinkovite kontracepcije.
The recommended dose is 30 mg once a week, injected on the same day each week.
Priporočeni odmerek je 30 mg enkrat na teden, injiciran vsak teden na isti dan.
Your doctor will decide if you can use Eperzan, and will explain the symptoms of pancreatitis (see ‘Conditions you need to look out for'
Zdravnik bo presodil, ali lahko uporabljate zdravilo Eperzan, in vas bo seznanil s simptomi pankreatitisa (glejte "Stanja na katera morate biti
You can use Eperzan at any time of day, with or without meals.
Zdravilo Eperzan lahko uporabite kadar koli tekom dneva, s hrano ali brez nje.
After that, you can go back to having your injection on the usual day.
Potem se lahko vrnete k injiciranju zdravila na vaš običajni dan.
The AUC of simvastatin acid was increased by 36% and Cmax was increased by approximately 100%.
simvastatinske kisline se je povečala za 36 %, Cmax pa se je povečala za približno 100 %.
If necessary you can change the day of the week on which you use Eperzan, as long as it is at least 4 days since your last dose.
lahko spremenite dan v tednu, na katerega uporabljate zdravilo Eperzan; pogoj je, da so minili vsaj 4 dnevi od vašega zadnjega odmerka.
Lift Pen from Skin
Dvignite peresnik s kože
(122 mild, 99 moderate, 15 severe)a
(122 blaga, 99 zmerna, 15 huda)a
The day of weekly administration can be changed if necessary as long as the last dose was administered 4 or more days previously.
Če je treba, se lahko dan tedenske uporabe spremeni; pogoj za to je, da je bil zadnji odmerek uporabljen 4 ali več dni pred tem.
• if you have Type 1 (insulin-dependent) diabetes or ketoacidosis (a very serious complication of diabetes which happens when your body is not able to break down glucose because there is not enough insulin), this medicine will not be right for you.
• če imate sladkorno bolezen tipa 1 (od insulina odvisno sladkorno bolezen) ali ketoacidozo (to je zelo resen zaplet sladkorne bolezni, ki se pojavi, kadar telo ne more uporabljati glukoze, ker ni dovolj insulina), to zdravilo ni pravo za vas.
Instruct the patient to read the full Instructions for Use (IFU) including the Questions and Answers before starting the therapy and refer back to the IFU each time before injecting the dose.
Bolnika poučite, naj prebere celotna Navodila za uporabo, vključno z Vprašanji in odgovori, pred začetkom zdravljenja ter se obrne na Navodila za uporabo vsakič pred injiciranjem odmerka.
This will mix the medicine powder and liquid.
To bo zmešalo prašek z zdravilom in tekočino.
For Eperzan, these were single episodes of pneumonia in patients participating in studies with 32 weeks up to 3 years of observation.
Z zdravilom Eperzan so bili to enkratni pojavi pljučnice pri bolnikih v študijah, ki so obsegale od 32 tednov do 3 let opazovanja.
The European Medicines Agency has deferred the obligation to submit the results of studies with Eperzan in one or more subsets of the paediatric population in the treatment of type 2 diabetes mellitus (see section 4.2 for information on paediatric use).
Evropska agencija za zdravila je začasno odložila zahtevo za predložitev rezultatov študij z zdravilom Eperzan za eno ali več podskupin pediatrične populacije za zdravljenje sladkorne bolezni tipa 2 (za podatke o uporabi pri pediatrični populaciji glejte poglavje 4.2).
As long as the needle has not been attached, the pen can be used for up to 8 hours from the time Step 2 was started.
Če še niste namestili igle, lahko peresnik uporabite v času do 8 ur po začetku 2. koraka.
Clean Empty Cup Clock/Timer min. sec.
Prazna, čista posodica Ura/štoparica min. sek.
Each pen contains a white to yellow powder and a colourless solvent in separate compartments.
Vsak peresnik vsebuje bel do rumen prašek in brezbarvno topilo (vehikel) v ločenih razdelkih.
Wait 15 Minutes
Počakajte 15 minut
It is acceptable to inject Eperzan and insulin in the same body region but the injections should not be adjacent to each other.
Sprejemljivo je injiciranje zdravila Eperzan in insulina v isti predel telesa, vendar mesti injiciranja ne smeta biti eno zraven drugega.
Choice of other medicinal products and dose selection should be considered accordingly, as adverse reactions may continue and efficacy may, at least partly, persist until albiglutide levels decline.
To je treba ustrezno upoštevati pri izbiri drugih zdravil in njihovega odmerka, ker se neželeni učinki lahko nadaljujejo, učinek pa lahko vsaj deloma traja, dokler se koncentracija albiglutida ne zniža.
Adverse reactions from phase III studies during the entire treatment periods and postmarketing reports
Neželeni učinki v študijah III. faze med celotnim obdobjem zdravljenja in poročilih iz obdobja po prihodu zdravila na trg.
These data exclude the use of antidiabetic therapies permitted after the efficacy assessment if glycaemic thresholds were exceeded.
Ti podatki ne vključujejo uporabe antidiabetičnih zdravil, dovoljenih po oceni učinkovitosti, če so bili preseženi pragi glikemije.
Patients treated with albiglutide should be advised of the potential risk of dehydration, and take precautions to avoid fluid depletion.
Bolnike, ki se zdravijo z albiglutidom, je treba poučiti o možnem tveganju dehidracije in jim svetovati ukrepe v izogib izgube tekočin.
Don't use Eperzan:
Ne uporabljajte zdravila Eperzan:
A few drops of liquid may come out of the needle.
Iz igle lahko priteče nekaj kapljic tekočine.
The needle must be attached to allow air to escape while turning the cartridge from [2] to [3] in the number window.
Iglo je treba namestiti, da gre lahko iz nje zrak, medtem ko sučete vložek z [2] na [3] v številčnem okencu.
The dose may be increased to 50 mg once weekly based on individual glycaemic response.
Odmerek je mogoče zvišati na 50 mg enkrat na teden glede na posameznikov glikemični odziv.
Speak to your doctor about how to recognise the symptoms of ketoacidosis and seek urgent medical treatment if they occur.
Z zdravnikom se posvetujte o tem, kako prepoznati simptome ketoacidoze; če se vam takšni simptomi pojavijo, poiščite nujno zdravniško pomoč.
Your doctor may increase your dose to 50 mg once weekly if your blood sugar is not controlled by the 30 mg dose.
Zdravnik vam lahko odmerek zviša na 50 mg enkrat na teden, če vaš krvni sladkor z odmerkom 30 mg ni urejen.
If you miss a dose, inject the next dose as soon as possible within 3 days after the missed dose.
Če izpustite odmerek, si naslednji odmerek injicirajte čim prej v 3 dneh po izpuščenem odmerku.
Japanese patients showed approximately 30 to 40% higher exposures than Caucasians, likely attributable to lower body weight.
Pri japonskih bolnikih je bila izpostavljenost približno 30 do 40 % večja kot pri belcih, verjetno zaradi manjše telesne mase.
In addition, albiglutide did not significantly alter the pharmacodynamic effects of warfarin as measured by the international normalized ratio.
Poleg tega albiglutid ni pomembno spremenil farmakodinamičnih učinkov varfarina, merjeno z internacionalnim normaliziranim razmerjem.
When Eperzan is added to existing metformin therapy, the current metformin dose can be continued unchanged.
Če je zdravilo Eperzan dodano obstoječemu zdravljenju z metforminom, se lahko metformin še naprej uporablja v nespremenjenem odmerku.
Step 8 Deliver injection 8a Insert needle straight into the injection site.
8. korak Injicirajte 8a Zabodite iglo naravnost v mesto za injiciranje.
Based on the results of population pharmacokinetic analyses, there is no clinically relevant effect of gender on clearance.
Na podlagi rezultatov populacijskih farmakokinetičnih analiz spol nima klinično pomembnega vpliva na očistek.
It is unknown whether the reduced offspring body weight was caused by a direct albiglutide effect on the offspring or secondary to effects on the dam.
Ni znano, ali je bil vzrok zmanjšane telesne mase mladičev neposreden učinek albiglutida na mladiče ali sekundaren zaradi učinkov na samice-matere.
Injection Button*
Gumb za injiciranje*
Check Medicine
Preverite zdravilo
Pharmacotherapeutic group: Drugs used in diabetes.
Farmakoterapevtska skupina: Zdravila za zdravljenje diabetesa.
At the end of this period the pen should be used or discarded.
Po koncu tega obdobja je treba peresnik uporabiti ali zavreči.
DO NOT use pen if there are still particles in the liquid.
NE UPORABITE peresnika, če so v tekočini še vedno delci.
Eperzan should be discontinued at least 1 month before a planned pregnancy due to the long washout period for albiglutide.
Zdravilo Eperzan je treba prenehati uporabljati vsaj 1 mesec pred načrtovano zanositvijo, ker je obdobje izpiranja albiglutida dolgo.
It may affect up to 1 in 100 people.
Pojavi se lahko pri do 1 od 100 oseb.
Never mix insulin and Eperzan together.
Insulina in zdravila Eperzan nikdar ne zmešajte.
Other Supplies Needed
Druge potrebščine
If pancreatitis is suspected, Eperzan should be discontinued; if pancreatitis is confirmed, Eperzan should not be restarted.
V primeru suma na pankreatitis je treba uporabo zdravila Eperzan prekiniti; če je pankreatitis potrjen, se zdravila Eperzan ne sme več uvesti.
If it has been more than 8 hours since the medicine was mixed in Step 2, throw away the pen and use another pen.
Če je od mešanja zdravila v 2. koraku minilo že več kot 8 ur, peresnik zavrzite in uporabite drugega.
Eperzan should be administered once a week on the same day each week.
Zdravilo Eperzan je treba uporabljati enkrat na teden, vsak teden na isti dan.
The most serious adverse reaction in clinical trials was acute pancreatitis (see section 4.4).
Najresnejši neželeni učinek v kliničnih preskušanjih je bil akutni pankreatitis (glejte poglavje 4.4).
IMPORTANT: Make sure you have waited 30 minutes before continuing onto step 4.
POMEMBNO: Prepričajte se, da ste počakali 30 minut, preden nadaljujete s 4. korakom.
Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Preobčutljivost na zdravilno učinkovino ali katero koli pomožno snov, navedeno v poglavju 6.1
Diarrhoea (13% versus 9%), nausea (12% versus 11%), vomiting (5% versus 4%), and constipation (5% versus 4%) were the most frequently reported, and the majority of events occurred within the first 6 months.
Najpogosteje zabeleženi so bili driska (13 % v primerjavi z 9 %), navzea (12 % v primerjavi z 11 %), bruhanje (5 % v primerjavi s 4 %) in zaprtost (5 % v primerjavi s 4 %); večina učinkov se je pojavila v prvih 6 mesecih.
If the pen is jammed or leaking, throw it away and use another pen.
Če se peresnik zatakne ali pušča, ga zavrzite in uporabite drugega.
Therapeutic proteins such as albiglutide are catabolised by widely distributed proteolytic enzymes, which are not restricted to hepatic tissue; therefore, changes in hepatic function are unlikely to have any effect on the elimination of Eperzan (see section 4.2).
Terapevtske beljakovine, kakršna je albiglutid, se katabolizirajo s široko razprostranjenimi proteolitičnimi encimi, ki niso omejeni na jetrno tkivo, zato ni verjetno, da bi spremembe delovanja jeter vplivale na odstranjevanje zdravila Eperzan (glejte poglavje 4.2).
Wait 30 Minutes
Počakajte 30 minut
8c After hearing the “click,” continue holding down the injection button and slowly count to 5 to deliver the full dose of medicine (Figure T).
8c Potem ko zaslišite "klik", še naprej držite gumb za injiciranje pritisnjen dol ter počasi preštejte do 5, da boste injicirali celotni odmerek zdravila (Slika T).
What if I do not attach the needle at Step 5?
Kaj, če igle ne namestim v 5. koraku?
A decrease in halflife of simvastatin and simvastatin acid from ~7 hours to 3.5 hours was observed.
Razpolovni čas simvastatina in simvastatinske kisline se je skrajšal s ~7 ur na 3,5 ure.
DO NOT rest the back of the device (where the injection button is exposed) on a flat surface while removing needle caps.
NE POLAGAJTE zadnjega dela peresnika (na katerem je izpostavljen gumb za injiciranje) na ravno površino, medtem ko snemate pokrovčka igle.
For full instructions on the reconstitution and administration of Eperzan see section 6.6 and the instructions for use included in the package leaflet.
Za celotna navodila za pripravo in dajanje zdravila Eperzan glejte poglavje 6.6 in navodila, ki jih vsebuje navodilo za uporabo.
These findings are consistent with lactational ileus syndrome which has been previously reported in mice.
Ti izsledki se skladajo s sindromom laktacijskega ileusa, ki je bil že opisan pri miših.
If it is more than 3 days since you missed your dose, wait until your usually scheduled day for your next injection.
Če so od tedaj, ko ste izpustili odmerek, minili že več kot 3 dnevi, počakajte na svoj običajni, predvideni dan za naslednjo injekcijo.
1c Check that the pen has a [1] in the number window (Figure F).
1c Preverite, da ima peresnik v številčnem okencu [1] (Slika F).
If the needle is attached before Step 5, some of the medicine may be lost during mixing.
Če iglo namestite prej kot v 5. koraku, lahko med mešanjem izgubite nekaj zdravila.
Generally, injection site reactions were mild in intensity and did not require treatment.
Na splošno so bile reakcije na mestu injiciranja blage in jih ni bilo treba zdraviti.
• A clean empty cup (Figure C).
• Prazno, čisto posodico (Slika C)
IMPORTANT: Make sure you have waited 15 minutes before continuing onto step 4.
POMEMBNO: Prepričajte se, da ste počakali 15 minut, preden nadaljujete s 4. korakom.
Throw out the pen in a container for pen disposal right away after injecting, as shown in Step 9.
Peresnik takoj po injiciranju zavrzite v vsebnik za odlaganje, kot je prikazano v 9. koraku.
Eperzan has not been studied in patients with severe gastrointestinal disease, including severe gastroparesis, and therefore it is not recommended in these patients.
Zdravilo Eperzan ni raziskano pri bolnikih s hudo boleznijo prebavil, vključno s hudo gastroparezo, zato pri takšnih bolnikih ni priporočljivo.
The use of Eperzan does not require specific blood glucose self-monitoring.
Uporaba zdravila Eperzan ne zahteva specifičnega samomerjenja glukoze v krvi.
Albiglutide is a recombinant fusion protein consisting of two copies of a 30-amino acid sequence of modified human glucagon-like peptide 1 genetically fused in series to human albumin.
Albiglutid je rekombinantna fuzijska beljakovina, sestavljena iz dveh kopij zaporedja 30 aminokislin modificiranega humanega glukagonu podobnega peptida 1, v zaporedjih genetsko vezanega na humani albumin.
The percentage of patients who developed antibodies to albiglutide on treatment was 4% (137/3,267).
Med zdravljenjem so se protitelesa proti albiglutidu pojavila pri 4 % (137/3.267) bolnikov.
In both the Eperzan and all comparator groups, patients with events were generally male, older, or had renal impairment.
Tako v skupini z zdravilom Eperzan kot v skupinah z vsemi primerjalnimi zdravili so bili bolniki z dogodki na splošno moški, starejši in z okvaro ledvic.
Caution should be exercised in patients receiving medicinal products with a narrow therapeutic index or medicinal products that require careful clinical monitoring.
zdravljenih z zdravili, ki imajo ozek terapevtski indeks ali zahtevajo skrbno klinično spremljanje.
In addition, a clinical pharmacology study showed a similar increased exposure for patients with moderate or severe renal impairment or those on haemodialysis relative to patients without renal impairment.
Poleg tega je klinična farmakološka študija pokazala podobno povečanje izpostavljenosti pri bolnikih z zmerno ali hudo okvaro ledvic ali tistih na hemodializi glede na bolnike brez okvare ledvic.
This is to make sure the medicine has dissolved.
Tako boste zagotovili, da se je zdravilo raztopilo.
Eperzan helps your body to increase the production of insulin when your blood sugar is high.
Zdravilo Eperzan telesu pomaga povečati nastajanje insulina, kadar imate visok krvni sladkor.
What Eperzan is and what it is used for
Kaj je zdravilo Eperzan in za kaj ga uporabljamo
Push Down Slowly
Počasi potiskajte dol
The pen has the medicine powder in one compartment and the water in another compartment.
Peresnik vsebuje v enem razdelku prašek z zdravilom in v drugem razdelku vodo.
• After the powder and liquid are mixed within the pen, the pen should be used within 8 hours.
• Po tem, ko prašek in tekočino v peresniku premešate, morate peresnik uporabiti v 8 urah.
Eperzan is not recommended if you have these
Zdravilo Eperzan ni priporočljivo, če imate te bolezni.
Thereafter, patients can resume dosing on their usual day of administration.
Potem lahko bolnik nadaljuje uporabo na svoj običajni dan dajanja zdravila.
Inspect the pen for ‘1' in the number window and expiration date.
Preglejte peresnik za številko "1" v številčnem okencu in datum uporabe.
Albiglutide is produced in Saccharomyces cerevisiae cells by recombinant DNA technology.
Albiglutid je pridobljen v celicah Saccharomyces cerevisiae s tehnologijo rekombinantne DNA.
If you are pregnant or breast-feeding, if you think you may be pregnant, or are planning to have a baby, ask your doctor, nurse or pharmacist for advice before using this medicine.
Če ste noseči ali dojite, menite, da bi lahko bili noseči ali načrtujete zanositev, se posvetujte z zdravnikom, medicinsko sestro ali farmacevtom, preden uporabite to zdravilo.
Active-controlled study versus sitagliptin in patients with type 2 diabetes and different degrees of renal impairment
Z aktivno učinkovino kontrolirana študija v primerjavi s sitagliptinom pri bolnikih s sladkorno boleznijo tipa 2 in različnimi stopnjami okvare ledvic
Among patients randomised to other comparators, the incidence of symptomatic hypoglycaemia was 7% to 33% when used with a sulphonylurea or insulin and 2% to 4% in combinations without these medicinal products.
Med bolniki, randomiziranimi na druga primerjalna zdravila, je bila incidenca simptomatskih hipoglikemij od 7 do 33 % med uporabo s sulfonilsečnino ali insulinom in od 2 do 4 % v kombinaciji brez teh zdravil.
Other medicines and Eperzan
Druga zdravila in zdravilo Eperzan
Severe allergic reactions
Resne alergijske reakcije
Complete dissolution for the 30 mg pen usually occurs within 2 minutes but may take up to 5 minutes, as confirmed by visual inspection for a clear solution free of particles.
Popolna raztopitev je s 30-mg peresnikom po navadi dosežena v 2 minutah, a lahko traja do 5 minut; raztopitev potrdite s pregledom raztopine, ki mora biti bistra in brez delcev.
Once weekly
Enkrat na teden