natgillin/translations-raw huggingface dataset:
In the total population, there was a reduction in the incidence of laboratory-confirmed clinical influenza in households from 20 % (27 / 136) in the group not receiving prevention to 7 % (10 / 135) in the group receiving prevention (62.7 % reduction [95 % CI 26.081.2; p = 0.0042]).
V celotni populaciji je bilo zmanjšanje v pojavnosti klinične laboratorijsko potrjene influence v gospodinjstvu iz 20 % (27/136) v skupini, ki ni prejemala zdravila za preprečevanje na 7 % (10/135) v skupini, ki je prejemala zdravilo za preprečevanje (62,7-% znižanje [95-% interval zaupanja 26,0 - 81,21; p = 0,0042]).
Altered level of consciousness, Convulsion
Bolezni živčevja glavobol nespečnost spremenjena raven zavesti, konvulzije
A study in older people in nursing homes, where 80 % of participants received vaccine in the season of the study, oseltamivir 75 mg once daily given for 6 weeks significantly reduced the incidence of clinical influenza illness from 12/272 (4.4 %) in the placebo group to 1/276 (0.4 %) in the oseltamivir group (92 % reduction [95 % CI 1.5 - 6.6; p = 0.0015]).
Študija med starejšimi ljudmi v domovih za ostarele, kjer je 80 % udeležencev prejelo cepivo v sezoni, ko je potekala študija, je pri jemanju oseltamivirja v odmerku 75 mg enkrat na dan 6 tednov, pokazala pomembno zmanjšanje pogostnosti klinične oblike gripe (1/276 (0,4 %)) v primerjavi s placebo skupino (12/272 (4,4 %)) (92-% zmanjšanje [95-% interval zaupanja 1,5 - 6,6; p = 0,0015]).
In the event that oseltamivir powder for oral suspension is not available, the pharmacist may compound a suspension (6 mg/ml) from Ebilfumin capsules.
V primeru, ko komercialno izdelanega oseltamivir praška za peroralno suspenzijo ni na voljo, lahko farmacevt pripravi suspenzijo (6 mg/ml) iz kapsul zdravila Ebilfumin.
Treatment of influenza infection
Zdravljenje okužbe z virusom influence
Prevention during an influenza epidemic in the community has not been studied in children below 12 years of age.
Preprečevanje gripe med epidemijo v okolici ni bilo preučevano pri otrocih, mlajših od 12 let.
• Sweet food to hide the bitter taste of the Ebilfumin.
• sladko hrano, ki bo zakrila grenak okus suspenzije zdravila Ebilfumin.
Additionally, diarrhoea and nappy rash have been reported.
Poleg tega so poročali še o driski in pleničnem izpuščaju.
Children 1 to 12 years Body weight
Otroci, stari od 1 do 12 let Telesna masa
When oseltamivir powder for oral suspension is not available Commercially manufactured oseltamivir powder for oral suspension (6 mg/ml) is the preferred product for paediatric and adult patients who have difficulties swallowing capsules or where lower doses are needed.
Kadar zdravila Ebilfumin prašek za peroralno suspenzijo ni na voljo Komercialno izdelan oseltamivir prašek za peroralno suspenzijo (6 mg/ml) je najbolj primernaen izdelekoblika za pediatrične in odrasle bolnike, ki imajo težave pri požiranju kapsul ali kjer so potrebni manjši odmerki.
75 mg once daily
75 mg enkrat na dan
This is to hide the bitter taste of the Ebilfumin powder.
To bo prikrilo grenak okus praška Ebilfumin.
The proportion of subjects who developed specified lower respiratory tract complications (mainly bronchitis) treated with antibiotics was reduced from 12.7 % (135/1,063) in the placebo group to 8.6 % (116/1,350) in the oseltamivir treated population (p = 0.0012).
Odstotek bolnikov, pri katerih so se pojavili opisani zapleti v spodnjem delu respiratornega trakta (v glavnem bronhitis) in so se zdravili z antibiotiki, je bil v placebo skupini 12,7 % (135/1.063), v skupini, ki se je zdravila z oseltamivirjem, pa 8,6 % (116/1.350; p = 0,0012).
20 capsules (600 mg)
20 kapsul (600 mg)
Treating flu:
Zdravljenje gripe:
There is no evidence for efficacy of oseltamivir in any illness caused by agents other than influenza viruses (see section 5.1).
O učinkovitosti oseltamivirja pri okužbah, ki jih ne povzročajo virusi influence, ni dokazov (glejte poglavje 5.1).
In the majority of patients, these ARs did not lead to discontinuation of oseltamivir.
Pri večini bolnikov zaradi teh neželenih učinkov ni prišlo do prekinitve zdravljenja z zdravilom Ebilfumin.
Children (1-12 years)
odrasli in mladostniki otroci (1-12 let)
3.0 ml (or 5.0 ml)
3,0 ml (ali 5,0 ml)
Step 1: Pour all the powder into a bowl
1. korak: Ves prašek stresite v posodo.
2.0 ml (or 3.0 ml)
2,0 ml (ali 3,0 ml)
These events are also experienced by patients with influenza without oseltamivir administration.
Ti dogodki so se pojavili tudi pri bolnikih z gripo, ki niso jemali oseltamivirja.
40 kg or more
40 kg ali več
The hard capsule consists of a white opaque body and a rich yellow cap bearing the black imprint “OS 75”.
Trda kapsula ima motno belo telo in rumen neprozoren pokrovček s črnim napisom “OS 75”.
Pour all of the powder into the bowl.
Ves prašek stresite v posodo.
Treatment of influenza in high risk populations: The median duration of influenza illness in older subjects (≥ 65 years) and in subjects with chronic cardiac and/or respiratory disease receiving oseltamivir 75 mg twice daily for 5 days was not reduced significantly.
(starih 65 let ali več) in pri bolnikih s kronično boleznijo srca ali dihal ali obojim, ki so prejemali odmerek 75 mg oseltamivirja dvakrat na dan 5 dni, ni bila pomembno znižana.
Caution should be exercised when preparing oseltamivir oral suspension and when administering oseltamivir products to children.
Pri pripravi peroralne suspenzije Ebilfumin in pri dajanju zdravila Ebilfumin otrokom je potrebna previdnost.
The virulence of influenza epidemics is not predictable and varies within a region and from season to season, therefore the number needed to treat (NNT) in order to prevent one case of influenza illness varies.
Virulenca epidemije gripe ni predvidljiva in se razlikuje glede na regijo in od sezone do sezone.
Do not try to make a 30 mg, 60 mg or 75 mg dose by using the contents of 45 mg capsules.
Ne poskušajte narediti 30 mg, 60 mg ali 75 mg odmerka z uporabo vsebine iz 45 mg kapsul, temveč uporabite kapsule z ustreznim odmerkom.
Pharmacy compounded 6 mg/ml suspension prepared from capsules
6 mg/ml suspenzija pripravljena v lekarni iz kapsul
The column on the right of the table shows how much of the liquid mixture you will need to draw up.
V stolpcu na desni strani preglednice poiščite ustrezno količino suspenzije zdravila Ebilfumin, ki jo boste potrebovali.
• Convulsion
• utrujenost
For instructions on preparing the extemporaneous formulation, see section 6.6.
Navodila za sprotno (ex-tempore) izdelavo so v poglavju 6.6.
12 capsules (360 mg)
12 kapsul (360 mg)
Yellow iron oxide (E172) Titanium dioxide (E171) Body:
želatina rumeni železov oksid (E172) titanov dioksid (E171) telo: želatina titanov dioksid (E171)
upper abdominal pain), Dyspepsia, Nausea
(vključno z bolečino v zgornjem delu trebuha), dispepsija, navzea
Yellow iron oxide (E172) Titanium dioxide (E171)
Ovojnica kapsule želatina rumeni železov oksid (E172) titanov dioksid (E171)
Refer to the table below for the proper dosing instructions.
Za ustrezna navodila za odmerjanje glejte spodnjo preglednico.
Prevention during an influenza epidemic in the community: In a pooled analysis of two other studies conducted in unvaccinated otherwise healthy adults, oseltamivir 75 mg once daily given for 6 weeks significantly reduced the incidence of clinical influenza illness from 25 /519 (4.8 %) in the placebo group to 6/520 (1.2 %) in the oseltamivir group (76 % reduction [95 % CI 1.6 - 5.7; p = 0.0006]) during a community outbreak of influenza.
Preprečevanje gripe med epidemijo v okolici: skupna analiza dveh drugih študij, ki so ju opravili pri necepljenih, sicer zdravih odraslih, ki so prejemali 75 mg oseltamivirja enkrat na dan 6 tednov, je pokazala pomembno zmanjšanje pogostnosti klinične oblike gripe v skupini, ki je jemala oseltamivir med izbruhom gripe v okolici (6/520 (1,2 %)) v primerjavi s placebo skupino (25/519, (4,8 %)) (76 %
Since 2007 naturally occurring resistance associated with the H275Y mutation in seasonal H1N1 strains has been sporadically detected.
Od leta 2007 so v sezonskih sevih H1N1
For measuring 12.5 ml of water, a 10 ml dispenser should be used.
Za odmerjanje 12,5 ml vode se mora uporabiti 10 ml odmernik.
Treatment of influenza
Zdravljenje gripe
Infants 0 - 12 months of age
Dojenčki, stari od 0 do 12 mesecev
18 capsules (540 mg)
18 kapsul (540 mg)
The following serious adverse reactions have been rarely reported since oseltamivir has been marketed: Anaphylactic and anaphylactoid reactions, hepatic disorders (fulminant hepatitis, hepatic function disorder and jaundice), angioneurotic oedema, Stevens-Johnson syndrome and toxic epidermal necrolysis, gastrointestinal bleeding and neuropsychiatric disorders.
Odkar je oseltamivir na tržišču so o naslednjih resnih neželenih učinkih poročali redko: anafilaktične in anafilaktoidne reakcije, bolezni jeter (fulminantni hepatitis, moteno delovanje jeter in zlatenica),
5.0 ml (or 10.0 ml)
5,0 ml (ali 10,0 ml)
Prevention of influenza: Dose adjustment is recommended for adults and adolescents (13 to 17 years of age) with moderate or severe renal impairment as detailed in the table below.
Preprečevanje gripe: prilagajanje odmerkov je priporočljivo za odrasle in mladostnike (stare od 13 do 17 let) z zmerno ali hudo ledvično okvaro.
The following age-adjusted dosing prophylaxis regimen is recommended for infants 0 - 12 months of age (see Section 5.2 for exposure simulation):
0 do 12 mesecev (za simulacijo izpostavljenosti glejte poglavje 5.2), je:
Adults and adolescents 13 years and over Body weight
Odrasli in mladostniki stari 13 let in več Telesna masa
The following serious side effects have been rarely reported since oseltamivir has been marketed:
Odkar je oseltamivir na tržišču so o naslednjih resnih neželenih učinkih poročali redko:
60 mg once daily
60 mg enkrat na dan
Prevention during an influenza epidemic in the community: Prevention during an influenza epidemic has not been studied in children below 12 years of age.
Preprečevanje gripe med epidemijo v okolici: Preprečevanje gripe med epidemijo v okolici ni bilo preučevano pri otrocih, mlajših od 12 let.
In a pooled analysis of all influenza-positive adults and adolescents (N = 2,413) enrolled into treatment studies, oseltamivir 75 mg twice daily for 5 days reduced the median duration of influenza illness by approximately one day from 5.2 days (95 % CI 4.9 - 5.5 days) in the placebo group to 4.2 days (95 % CI 4.0 - 4.4 days; p ≤ 0.0001).
75 mg dvakrat na dan 5 dni, je bila mediana trajanja okužbe z virusom influence zmanjšana za približno en dan - s 5,2 dneva (95-% interval zaupanja 4,9 - 5,5 dni) v placebo skupini na 4,2 dni (95% interval zaupanja 4,0 - 4,4 dni; p ≤ 0,0001).
See Making Liquid Ebilfumin at home for instructions.
Za navodila glejte Priprava tekočega zdravila Ebilfumin doma.
25 capsules (750 mg)
25 kapsul (750 mg)
3 kg to 10+ kg
3 kg do 10 in več kg
Contents of the pack and other information
Shranjevanje zdravila Ebilfumin Vsebina pakiranja in dodatne informacije
8 capsules (360 mg)
8 kapsul (360 mg)
Erythema multiforme, Stevens-Johnson syndrome, Toxic epidermal necrolysis
angionevrotični edem, Stevens-Johnson sindrom in toksična epidermalna nekroliza, krvavitve v prebavilih in nevropsihiatrične bolezni.
Posology and method of administration) results in an increased exposure (of up to 50%) to the active metabolite when compared to adult nonimmunocompromised patients with comparable creatinine clearance.
Populacijska farmakokinetična analiza kaže, da zdravljenje odraslih imunsko ogroženih bolnikov z oseltamivirjem (kot je opisano v poglavju 4.2 Odmerjanje in način uporabe) povzroči povečano izpostavljenost (do 50 %) aktivnemu presnovku v primerjavi z imunsko neogroženimi odraslimi bolniki s primerljivim očistkom kreatinina.
• One or two 30 mg Ebilfumin capsule(s)
• eno ali dve 30 mg kapsuli zdravila Ebilfumin
• One 75 mg Ebilfumin capsule
• eno 75 mg kapsulo zdravila Ebilfumin
Step 2: Pour all the powder into a bowl
2. korak: Ves prašek stresite v posodo.
Prevention during an influenza epidemic in the community: Prevention during an influenza epidemic has not been studied in children 0-12 months of age.
Preprečevanje gripe med epidemijo v okolici: Preprečevanje gripe med epidemijo v okolici ni bilo preučevano pri otrocih, starih od 0 do 12 mesecev.
You must tell your doctor if you are breast-feeding so that your doctor can decide if Ebilfumin is right for you.
Če dojite, obvestite zdravnika, ki bo odločil o tem, ali boste prejeli zdravilo Ebilfumin ali ne.
Ebilfumin 30 mg hard capsules
Ebilfumin 30 mg trde kapsule
Do not try to make a 45 mg or 75 mg dose by using the contents of 30 mg capsules.
Ne poskušajte narediti 45 mg ali 75 mg odmerka z uporabo vsebine iz 30 mg kapsul, temveč uporabite kapsule z ustreznim odmerkom.
Reversible irritancy of rabbits' eyes was detected.
Pri kuncih so opazili reverzibilno vzdraženost oči.
- The other ingredients are: capsule contents: pregelatinized starch (derived from maize starch), talc, povidone (K-29/32), croscarmellose sodium, sodium stearyl fumarate capsule shell: cap: gelatin, yellow iron oxide (E172) and titanium dioxide (E171), body: gelatin, titanium dioxide (E171) printing ink: shellac glaze-45% (20% esterified), black iron oxide (E172), propylene glycol (E1520), ammonium hydroxide 28% (E527)
- Pomožne snovi so: vsebina kapsule: predgelirani škrob (pridobljen iz koruznega škroba), smukec, povidon (K29/32), natrijev premrežen karmelozat in natrijev stearilfumarat; ovojnica kapsule: želatina, rumeni železov oksid (E172) in titanov dioksid (E171); tiskarsko črnilo: šelak-45% (20% zaestreno), črni železov oksid (E172), propilenglikol (E1520), 28% amonijev hidroksid (E527)
Ebilfumin 75 mg hard capsules
Ebilfumin 75 mg trde kapsule
12.5 ml twice daily 12.5 ml once daily
12,5 ml dvakrat na dan 12,5 ml enkrat na dan
18 mg twice daily
18 mg dvakrat na dan
8 capsules (600 mg)
8 kapsul (600 mg)
Step 3: Sweeten the powder and give the dose
3. korak: Sladkajte suspenzijo in jo dajte bolniku.
Treatment: The recommended oral dose is 75 mg oseltamivir twice daily for 5 days for adolescents (13 to 17 years of age) and adults.
Zdravljenje: priporočeni peroralni odmerek za mladostnike (stare od 13 do 17 let) in odrasle je 75 mg oseltamivirja dvakrat na dan, 5 dni.
7.5 ml twice daily 7.5 ml once daily
7,5 ml dvakrat na dan 7,5 ml enkrat na dan
Step 4: Draw up the liquid mixture
4. korak: Povlecite suspenzijo v odmernik.
Oseltamivir significantly reduced the incidence of clinical influenza illness occurring in the contacts of confirmed influenza cases from 24/200 (12 %) in the placebo group to 2/205 (1 %) in the oseltamivir group (92 % reduction [95 % CI 6 - 16; p ≤ 0.0001]).
V skupini, ki je jemala oseltamivir, je bila pogostnost pojava klinične gripe, ki se je pojavila po stiku z bolniki, okuženimi z virusom influence, pomembno zmanjšana (2/205 (1 %) v primerjavi s placebo skupino (24/200 (12 %)) (92-% zmanjšanje [95-%
The hard capsule consists of a rich yellow body and cap bearing the black imprint “OS 30”.
Trda kapsula ima rumeno neprozorno telo in pokrov s črnim napisom “OS 30”.
How to take Ebilfumin
Kako se uporablja zdravilo Ebilfumin
9 mg twice daily
9 mg dvakrat na dan
The hard capsule consists of a white opaque body and cap bearing the black imprint “OS 45”.
Trda kapsula ima motno belo telo in pokrov s črnim napisom “OS 45”.
EU/1/14/915/005 (10 hard capsules blister) EU/1/14/915/006 (10 hard capsules container)
EU/1/14/915/005 (10 trdih kapsul v pretisnem omotu) EU/1/14/915/006 (10 trdih kapsul v HDPE vsebniku)
12 capsules (540 mg)
12 kapsul (540 mg)
The lower predicted exposure however, remains above inhibitory concentrations (IC95 values) and at a therapeutic level for a range of influenza virus strains.
(vrednosti IC 95) in v terapevtskem nivoju za vrsto sevov virusa gripe.
Post-exposure prevention: The recommended prophylaxis dose for infants less than 1 year of age during a pandemic influenza outbreak is half of the daily treatment dose.
mlajših od 1 leta, je polovica dnevnega odmerka za zdravljenje, med izbruhom pandemije gripe.
Add a small amount - no more than one teaspoonful - of a sweet food to the second bowl.
V drugo posodo dodajte majhno količino sladke hrane (največ eno čajno žličko).
No studies have been carried out in paediatric patients with hepatic disorder.
Študij pri otrocih z jetrno boleznijo niso izvajali.
Total volume to compound per patient weight (ml) Measurement loss considered
Celokupni volumen, ki ga je potrebno pripraviti glede na bolnikovo telesno maso (ml) Meritvene izgube so upoštevane
Pack-size 10 capsules.
V pakiranju po 10 kapsul.
Ebilfumin 30 mg hard capsules are available in blister packs or tablet containers of 10.
Trde kapsule zdravila Ebilfumin 30 mg so na voljo v pretisnih omotih po 10 kapsul.
Prophylaxis of influenza in immunocompromised patients: A double-blind, placebo-controlled, randomised study was conducted for seasonal prophylaxis of influenza in 475 immunocompromised patients (388 patients with solid organ transplantation [195 placebo; 193 oseltamivir], 87 patients with haemopoetic stem cell transplantation [43 placebo; 44 oseltamivir], no patient with other immunosuppressant conditions), including 18 children 1 to 12 years of age.
87 bolnikov s presajenimi krvotvornimi matičnimi celicami [43 bolnikov je prejemalo placebo, 44 pa oseltamivir], bolnikov z drugimi stanji, ki bi zmanjšale imunski odziv ni bilo) vključno z 18 otroki,
This includes medicines obtained without a prescription.
Predpisovanje in izdaja zdravila je le na recept.
Ebilfumin 75 mg hard capsules are available in blister packs or tablet containers of 10.
Trde kapsule zdravila Ebilfumin 75 mg so na voljo v pretisnih omotih po 10 kapsul.
How to store Ebilfumin
Shranjevanje zdravila Ebilfumin
Fulminant hepatitis, Hepatic failure, Hepatitis
žolčnika in žolčevodov zvišane vrednosti jetrnih encimov fulminantni hepatitis, odpoved jeter, hepatitis
• One 45 mg Ebilfumin capsule
• eno 45 mg kapsulo zdravila Ebilfumin
oseltamivir significantly reduced the incidence of specified lower respiratory tract complications (mainly bronchitis) treated with antibiotics from 19 % (52/268) in the placebo group to 12 % (29/250) in the oseltamivir treated population (p = 0.0156).
Pri starejših bolnikih, okuženih z virusom influence, je bila pogostnost specifičnih zapletov spodnjega respiratornega trakta (v glavnem bronhitisa), zdravljenih z antibiotiki, v skupini, ki je prejemala oseltamivir, pomembno zmanjšana v primerjavi s skupino, ki je jemala placebo (12 % (29/250) proti 19 % (52/268); p = 0,0156).
Visual disturbance
Očesne bolezni motnje vida
• One 30 mg Ebilfumin capsule
• eno 30 mg kapsulo zdravila Ebilfumin
In lactating rats, oseltamivir and the active metabolite are excreted in the milk.
Pri podganah so med laktacijo opazili izločanje oseltamivirja in aktivnega presnovka v mleko.
10 capsules (750 mg)
10 kapsul (750 mg)
The indication in infants below the age of 1 is based upon extrapolation of efficacy data from older children and the recommended posology is based upon pharmacokinetic modelling data (see Section 5.2).
Priporočeno odmerjanje temelji na podatkih, pridobljenih s farmakokinetičnim modeliranjem (glejte poglavje 5.2).
Ebilfumin 45 mg hard capsules are available in blister packs or tablet containers of 10.
Trde kapsule zdravila Ebilfumin 45 mg so na voljo v pretisnih omotih po 10 kapsul.
Post-exposure prevention of influenza in infants less than 1 year of age during a pandemic: Prevention during an influenza pandemic has not been studied in controlled clinical studies in children 0-12 months of age.
Preprečevanja gripe med pandemijo v nadzorovanih kliničnih študijah pri otrocih v starosti 0-12 mesecev niso proučevali.
Hold a 75 mg capsule upright over a bowl and carefully snip off the rounded tip with scissors.
75 mg kapsulo držite navpično nad posodo in s škarjami odrežite zaobljeno konico.
Efficacy of oseltamivir in the treatment of subjects with chronic cardiac disease and/or respiratory disease has not been established.
Učinkovitost oseltamivirja pri bolnikih s kronično boleznijo srca ali boleznijo dihal ali obojim ni znana.
EU/1/14/915/003 (10 hard capsules container) EU/1/14/915/004 (10 hard capsules blister)
EU/1/14/915/003 (10 trdih kapsul v HDPE vsebniku) EU/1/14/915/004 (10 trdih kapsul v pretisnem omotu)
Hold a 30 mg capsule upright over a bowl and carefully snip off the rounded tip with scissors.
30 mg kapsulo držite navpično nad posodo in s škarjami odrežite zaobljeno konico.
Ebilfumin 45 mg hard capsules
Ebilfumin 45 mg trde kapsule
If possible, mark or highlight the graduation corresponding to the appropriate dose (according to the dosing tables above) on the oral syringe for each patient.
Suspenzijo, pripravljeno v lekarni, opremite z graduirano brizgo za peroralno dajanje, namenjeno za merjenje majhnih količin suspenzije.Če je mogoče, označite za vsakega bolnika posebej volumen na brizgi za peroralno dajanje, ki ustreza določenemu odmerku (glede na zgornjo preglednico za odmerjanje).
Please use
Način uporabe
Teratology studies have been conducted in rats and rabbits at doses of up to 1,500 mg/kg/day and 500 mg/kg/day, respectively.
Študije teratogenosti pri podganah, ki so prejemale odmerke do 1.500 mg/kg/dan, in pri kuncih, ki so prejemali odmerke do 500 mg/kg/dan, niso pokazale vplivov na razvoj zarodka.
No dose adjustment is required either for treatment or for prevention in patients with hepatic dysfunction.
Pri bolnikih z motenim jetrnim delovanjem prilagajanje odmerkov za zdravljenje ali preprečevanje gripe ni potrebno.
45 mg once daily
45 mg enkrat na dan
These events were reported primarily among paediatric and adolescent patients and often had an abrupt onset and rapid resolution.
O teh dogodkih so poročali predvsem pri pediatričnih bolnikih in mladostnikih.
(These may affect up to 1 in 1,000 people)
(pojavijo se lahko pri največ 1 od 1.000 bolnikov)
No pharmacokinetic interactions between oseltamivir or its major metabolite have been observed when co-administering oseltamivir with paracetamol, acetylsalicylic acid, cimetidine, antacids (magnesium and aluminium hydroxides and calcium carbonates), rimantadine or warfarin (in subjects stable on warfarin and without influenza).
(magnezijevi in aluminijevi hidroksidi ter kalcijevi karbonati), rimantadina ali varfarina (pri osebah, ki so bile z jemanjem varfarina stabilne in brez gripe) niso opazili farmakokinetičnih interakcij med oseltamivirjem ali njegovim glavnim presnovkom.
24 mg twice daily
24 mg dvakrat na dan
Hold a 45 mg capsule upright over a bowl and carefully snip off the rounded tip with scissors.
45 mg kapsulo držite navpično nad posodo in s škarjami odrežite zaobljeno konico.
6 capsules (450 mg)
6 kapsul (450 mg)
Ebilfumin 75 mg hard capsules oseltamivir
Ebilfumin 75 mg trde kapsule oseltamivir
This is to hide the bitter taste of the Ebilfumin.
To bo zakrilo grenak okus suspenzije zdravila Ebilfumin.
Ebilfumin 30 mg hard capsules oseltamivir
Ebilfumin 30 mg trde kapsule oseltamivir
15 mg twice daily
15 mg dvakrat na dan
However, care should be taken when prescribing oseltamivir in subjects when taking co-excreted agents with a narrow therapeutic margin (e.g. chlorpropamide, methotrexate, phenylbutazone).
Pri predpisovanju oseltamivirja bolnikom, ki sočasno jemljejo zdravila, ki se izločajo enako kot oseltamivir in imajo ozko terapevtsko okno (npr. klorpropamid, metotreksat,
Infants less than 1 year (including full-term newborn babies): Dose of Ebilfumin
Dojenčki, mlajši od 1 leta (vključno z donošenimi novorojenčki):
Oseltamivir reduced the incidence of acute otitis media from 26.5 % (53/200) in the placebo group to 16 % (29/183) in the oseltamivir treated children (p = 0.013).
Pogostnost akutnega vnetja srednjega ušesa je bila v skupini otrok, ki je jemala oseltamivir, manjša (16 % (29/183)) v primerjavi s skupino, ki je jemala placebo (26,5 % (53/200)) (p = 0,013).
The median duration of illness in influenza B infected subjects did not differ significantly between the treatment groups in individual studies.
se med posameznimi skupinami v študijah ni pomembno razlikovala.
EU/1/14/915/001 (10 hard capsules blister) EU/1/14/915/002 (10 hard capsules container)
EU/1/14/915/001 (10 trdih kapsul v pretisnem omotu) EU/1/14/915/002 (10 trdih kapsul v HDPE vsebniku)