natgillin/translations-raw huggingface dataset:
Ruconest must be administered by a healthcare professional until the patient (or caregiver) is competent to administer after having been properly trained and in agreement with the healthcare professional.
Zdravilo Ruconest mora dajati zdravstveni delavec, dokler bolnik (ali skrbnik) po ustreznem usposabljanju in v dogovoru z zdravstvenim delavcem ni zadostno usposobljen za samostojno dajanje.
• Draw in the volume of prepared solution, while keeping the syringe in the vertical position.
• Izsesajte količino pripravljene raztopine, pri čemer naj bo brizga v navpičnem položaju.
Preclinical data do not indicate any safety concern for the use of conestat alfa in humans based on studies of safety pharmacology, single-dose toxicity, two-week sub-chronic toxicity and local tolerance in various animal species including rats, dogs, rabbits and cynomolgus monkeys.
Predklinični podatki na osnovi običajnih študij farmakološke varnosti, toksičnosti enkratnega odmerka, dvotedenske subkronične toksičnosti in lokalne tolerance pri različnih živalskih vrstah, vključno s podganami, psi, kunci in javanskimi makaki, ne kažejo posebnega tveganja za človeka.
• Carefully pull back the syringe plunger slightly until you see blood being drawn into the tubing, to ensure that the needle is in the vein.
• Previdno rahlo povlecite bat brizge, dokler v cevki ne zagledate krvi, s tem se boste prepričali, da je igla v žili.
• Abdominal pain, diarrhoea, nausea
• Bolečine v trebuhu, diareja, slabost
The patient card should contain the following key elements:
Opozorilna kartica za bolnika mora vsebovati naslednje ključne elemente:
For patients of 84 kg or above the volume required to be administered is 28 ml, corresponding to 4200 U (2 vials).
Za bolnike s telesno maso 84 kg ali več je potrebni volumen za dajanje 28 ml, kar ustreza 4200 e. (2 viali).
If you plan becoming pregnant, discuss with your doctor before starting to use Ruconest.
Če načrtujete zanositev, se posvetujte z zdravnikom, preden vzamete to zdravilo.
No dose adjustment is necessary in patients with renal impairment since conestat alfa does not undergo renal clearance.
Pri bolnikih z ledvično okvaro ni potrebna prilagoditev odmerka, saj se konestat alfa ne izloča prek ledvic.
- Body weight up to 84 kg
- Telesna masa do 84 kg
The medicinal product should be used immediately.
Zdravilo je treba takoj uporabiti.
• The fact that Ruconest is derived from milk of transgenic rabbits and contains trace of rabbit proteins (Host Related Impurities, HRI).
• Dejstva, da se zdravilo Ruconest pridobiva iz mleka transgenskih kuncev in vsebuje sledove kunčjih beljakovin (nečistote, povezane z gostiteljem: HRI - Host Related Impurities).
• There are limited data on the use of this medicinal product in home or self-administration.
• Podatkov o uporabi tega zdravila pri zdravljenju doma ali samostojnem dajanju je malo.
Some side effects may occur during treatment with Ruconest: Common: may affect up to 1 in 10 people
Med zdravljenjem z zdravilom Ruconest se lahko pojavijo nekateri neželeni učinki: Pogosti (pojavijo se lahko pri največ 1 od 10 bolnikov):
Step 11: Preparing the injection site
11. korak: Priprava mesta za injiciranje
Do not use this medicine after the expiry date which is stated on the carton and on the label of the vial after EXP.
Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, ki je naveden na škatli in na oznaki viale poleg oznake EXP. Rok uporabnosti zdravila se izteče na zadnji dan navedenega meseca.
The administration of Ruconest is to resolve the shortage of C1 inhibitor and will lead to reduction of symptoms of an acute attack of HAE.
Z dajanjem zdravila Ruconest odpravimo pomanjkanje zaviralca C1 in zmanjšamo simptome akutnega napada angioedema.
Do not drive or use machinery if you feel dizzy or suffer from headache after using Ruconest.
Ne vozite avtomobila ali upravljajte z orodji ali stroji, če imate po uporabi zdravila Ruconest vrtoglavico ali glavobol.
• the batch number written on the label of the powder vial
• številko serije na nalepki viale s praškom
Inject the Ruconest solution immediately after preparation, preferably while seated.
Raztopino zdravila Ruconest injicirajte nemudoma po pripravi, če je mogoče, v sedečem položaju.
Conestat alfa is derived from milk of transgenic rabbits and contains traces of rabbit protein.
Konestat alfa je pridobljen iz mleka transgenskih kuncev in vsebuje sledove kunčjih beljakovin.
• Hives and swelling of the skin.
• Koprivnica in otekanje kože.
• Carefully remove the plaster for securing the needle and withdraw the needle from the vein.
• Previdno odstranite obliž za pritrditev igle in jo odstranite iz žile.
Ruconest must be administered by a healthcare professional until you or your caregiver are properly trained and capable to administer Ruconest.
Zdravilo Ruconest mora dajati zdravstveni delavec, dokler vi ali vaš skrbnik niste zadostno usposobljeni in zmožni za dajanje zdravila Ruconest.
1 powder vial 1 solvent vial 2 vial adapters 1 syringe
1 vialo s praškom 1 vialo z vehiklom 2 adapterja za viale 1 brizgo
In the majority of cases a single dose of Ruconest is sufficient to treat an acute angioedema attack.
V večini primerov za zdravljenje akutnega napada angioedema zadostuje en odmerek zdravila
Very common (≥1/10), Common (≥1/100 to <1/10), Uncommon (≥1/1,000 to <1/100), Rare (≥1/10,000 to <1/1,000),
Pogostnost neželenih učinkov v nadaljevanju je opredeljena v skladu z naslednjo klasifikacijo: zelo pogosti (≥1/10), pogosti (≥1/100 do <1/10), občasni (≥1/1.000 do <1/100), redki (≥1/10.000 do <1/1.000),
Based on animal data, conestat alfa is cleared from the circulation by the liver via receptor-mediated endocytosis followed by complete hydrolysis/degradation.
Na podlagi podatkov študij na živalih se konestat alfa očisti iz krvnega obtoka s presnovo v jetrih z od receptorja odvisno endocitozo, ki ji sledi popolna hidroliza/razgradnja.
Home-treatment and self-administration
Zdravljenje doma in samostojno dajanje
If air bubbles appear, minimise as far as possible by gently tapping the syringe and applying gentle pressure by pushing the plunger into the syringe.
Če se pojavijo mehurčki, jih poskusite čim bolj omejiti z nežnim trepljanjem brizge in nežnim pritiskanjem bata v brizgo.
• That patients treated with Ruconest should be monitored for clinical signs and symptoms of hypersensitivity during administration.
• Da je treba bolnike, zdravljene z zdravilom Ruconest, med dajanjem spremljati glede preobčutljivostnih kliničnih znakov in simptomov.
Patients should be informed of the early signs of hypersensitivity reactions including hives, generalised urticaria, tightness of the chest, wheezing, hypotension and anaphylaxis.
Bolnike je treba poučiti o zgodnjih znakih preobčutljivostnih reakcij, ki vključujejo koprivnico, generalizirano urtikarijo, stiskanje v prsih, hropenje, hipotenzijo in anafilakso.
- Body weight up to 84 kg For patients up to 84 kg calculate the volume required to be administered according to the formula below:
- Telesna masa do 84 kg Za bolnike s telesno maso do 84 kg izračunajte potrebni volumen v skladu s spodnjo preglednico:
• It is the responsibility of the physician to provide the patient or a caregiver with instructions and training on administration outside of a clinic setting.
• Zdravnik mora bolnika ali njegovega skrbnika poučiti in usposobiti za dajanje zdravila zunaj bolnišnične ustanove.
• Turn the whole - solvent vial with adapter and syringe - upside down.
• Celotni sestav - vialo z vehiklom, adapter in brizgo - obrnite na glavo.
Ruconest should be administered by a healthcare professional.
Zdravilo Ruconest mora dati zdravstveni delavec.
It is not recommended to use Ruconest during pregnancy or breast-feeding.
Uporaba zdravila Ruconest med nosečnostjo ali dojenjem ni priporočena.
• Immediately after removing the needle, press the sterile pad on the injection site for a few minutes to reduce bleeding.
• Takoj po odstranitvi igle na mesto injiciranja pritisnite sterilni tampon in ga držite nekaj minut,
1 infusion set with needle 2 alcohol pads 1 sterile non-woven pad 1 adhesive plaster
1 komplet za infundiranje z iglo 2 alkoholni blazinici 1 sterilni netkani tampon 1 obliž
After administration of Ruconest (50 U/kg) to asymptomatic HAE patients, a Cmax of 1.36 U/ml was observed.
Po dajanju zdravila Ruconest (50 e./kg) asimptomatičnim bolnikom s HAE so izmerili Cmaks 1,36 e./ml.
- bodyweight 42 kg or less: 1 powder and 1 solvent vial - bodyweight over 42 kg: 2 powder and 2 solvent vials
- telesna masa do 42 kg: 1 viala s praškom in 1 viala z vehiklom - telesna masa nad 42 kg: 2 viali s praškom in 2 viali z vehiklom
• It is the responsibility of the physician to verify that all the necessary skills have been acquired by the non-Healthcare Professional and that Ruconest may be safely and effectively administered outside of a Healthcare Professional setting.
• Zdravnik je dolžan preveriti, da je nezdravstveni delavec razvil vse potrebne spretnosti ter da je omogočeno varno in učinkovito dajanje zdravila Ruconest zunaj zdravstvene ambulante.
Step 3: Mounting of adapters on vials
3. korak: Namestitev adapterjev na viale
Conestat alfa, recombinant human complement component 1 (C1) esterase inhibitor (rhC1INH), is an analogue of human C1INH and is obtained from the milk of rabbits expressing the gene encoding for human C1INH.
Konestat alfa, rekombinantna humana sestavina komplementa 1 (C1) zaviralca esteraze (rhC1INH), je analog humanega C1INH in se ga pridobiva iz mleka kuncev, ki izražajo kodiranje gena za humani
• 1 vial of 2100 U powder
• 1 vialo z 2100 e. praška
Solvent vial: Water for injections
Viala z vehiklom: voda za injekcije
Millilitres of prepared solution to be injected below 84 kg bodyweight in kg divided by three
Število mililitrov, ki jih je treba injicirati do 84 kg telesna masa v kg deljeno s tri več kot 84 kg
- Body weight of 84 kg or greater
- Telesna masa 84 kg ali več
The efficacy and safety of Ruconest as a treatment of acute angioedema attacks in patients with HAE has been evaluated in two double blind randomized placebo controlled and four open label clinical studies.
HAE so ocenili v dveh dvojno slepih, randomiziranih, s placebom nadzorovanih študijah in štirih odprtih kliničnih študijah.
Water for injections should be added slowly to avoid forceful impact on the powder and mixed gently to minimise foaming of the solution.
Vodo za injekcije je treba dodati počasi, da se izognete močnemu curku na prašek, in rahlo premešati, da v največji možni meri omejite penjenje raztopine.
• Dizziness, throat irritation
• Vrtoglavica, draženje v grlu
Leave the syringe on the adapter.
Brizgo pustite pritrjeno na adapter.
Powder for solution for injection 1 vial
prašek za raztopino za injiciranje 1 viala
Conestat alfa is a recombinant (not blood-derived) form of human C1 inhibitor (rhC1INH).
Konestat alfa je rekombinantna (ni proizvedena iz krvi) oblika humanega zaviralca C1 (rhC1INH).
Remove the needle cap from the needle of the infusion set and carefully insert the needle into the vein.
Odstranite pokrovček igle s kompleta za infundiranje in jo previdno vstavite v žilo.
• Safely dispose of the used infusion set with needle, any unused solution, the syringe and the empty vial in an appropriate medical waste container as these materials may hurt others if not disposed of properly.
• Uporabljeni komplet za infundiranje skupaj z iglo, vso neporabljeno raztopino, brizgo in prazno vialo varno odstranite v ustrezni zabojnik za medicinske odpadke, saj lahko ti pripomočki poškodujejo druge, če niso primerno odstranjeni.
Conestat alfa is the recombinant analogue of the human C1 esterase inhibitor (rhC1INH) produced by recombinant DNA technology in the milk of transgenic rabbits.
Konestat alfa je rekombinantni analog humanega zaviralca esteraze C1 (rhC1INH), pridobljen s tehnologijo rekombinantne DNA v mleku transgenskih kuncev.
• Hold the adapter with the other hand and attach the syringe.
• Z drugo roko primite adapter in namestite brizgo.
Ruconest is to be used by adults and adolescents with a rare inherited blood disorder, called Hereditary Angioedema (HAE).
Zdravilo Ruconest lahko uporabljajo odrasli in mladostniki z redko dedno krvno boleznijo, imenovano dedni (hereditarni) angioedem.
• Use of Ruconest is only approved in acute attacks of hereditary angioedema.
• Zdravilo Ruconest se lahko uporablja samo pri akutnih napadih hereditarnega (dednega) angioedema.
Please safely dispose of the used infusion set with needle, any unused solution, the syringe and the empty vial in an appropriate medical waste container as these materials may hurt others if not disposed of properly.
Odstranjevanje Prosimo, da uporabljeni komplet za infundiranje skupaj z iglo, vso neporabljeno raztopino, brizgo in prazno vialo varno odstranite v ustrezni zabojnik za medicinske odpadke, saj lahko ti pripomočki poškodujejo druge, če niso primerno odstranjeni.
Inhibition kinetics were found to be comparable with those observed for plasma-derived human C1INH.
Ugotovili so, da je kinetika zaviranja primerljiva s tisto, ugotovljeno za humani C1INH, pridobljen iz plazme.
• Batch number and dose
• Številko serije in odmerek zdravila
Ruconest is presented as a single glass vial containing a white to off-white powder for solution for injection together with one glass vial containg a clear, colourless solvent to dissolve the powder.
Zdravilo Ruconest je pakirano kot ena steklena viala z belim do belkastim praškom za raztopino za injiciranje skupaj s stekleno vialo, ki vsebuje bistro, brezbarvno tekočino za raztopitev praška.
One case of hypersensitivity was observed in clinical trials with Ruconest.
V kliničnih preizkušanjih z zdravilom Ruconest so opazili en primer preobčutljivosti.
100 U/kg n =16
100 e/kg n =16
While keeping it vertical, slowly draw in 14 ml solvent.
Držite ga v navpičnem položaju in počasi izsesajte 14 ml vehikla.
Name and address of the manufacturers of the biological active substance
SPROŠČANJE SERIJ Ime in naslov izdelovalcev biološke zdravilne učinkovine
• Secure the needle by applying the plaster, around 7 cm long, over the wings of the needle.
• Obliž dolžine približno 7 cm namestite čez krilca in zavarujte iglo.
• Hives and swelling of the skin
• Koprivnica in otekanje kože
• Summary of Product Characteristics and Patient Information Leaflet for Ruconest
• Povzetek glavnih značilnosti zdravila in navodilo za uporabo za zdravilo Ruconest.
- unfold the tubing and gently inject this solution, similar to the first syringe
- sprostite cevko in nežno injicirajte to raztopino po enakem postopku kot prvo 13. korak: Po injiciranju
Abdominal discomfort Oral paraesthesia
Bolezni prebavil diareja slabost nelagodje v trebuhu oralna parestezija
50 U/kg n =12
50 e/kg n =12
Ruconest will be initiated by a doctor who is specialised in the diagnosis and treatment of hereditary angioedema.
Zdravilo Ruconest bo uvedel zdravnik specialist za diagnosticiranje in zdravljenje hereditarnega angioedema.
• Copies of the patient card to be given to patients before they receive Ruconest.
• Opozorilno kartico za bolnika, ki jo mora bolnik prejeti pred začetkom uporabe zdravila
• That they are receiving Ruconest for treatment of acute attack of hereditary angioedema.
• Da prejemajo zdravilo Ruconest za zdravljenje akutnih napadov dednega angioedema.
• Remove the needle cap.
• Odstranite pokrov igle.
Draw in the required volume of prepared solution.
Izsesajte zahtevano količino pripravljene raztopine.
In the randomized controlled trials 39/41 (95%) of patients treated with Ruconest reached time to beginning of relief within 4 hours.
V randomiziranih, nadzorovanih študijah je 39/41 (95 %) bolnikov, zdravljenih z zdravilom Ruconest,
• Next, put the self-adhesive plaster on the injection site.
• Nato na mesto injiciranja namestite samolepilni obliž.
Ruconest is supplied with an administration kit in a carton box containing:
Zdravilo Ruconest je na voljo skupaj s kompletom za dajanje zdravila v kartonski škatli, ki vsebuje:
Talk to your doctor before using Ruconest.
Pred uporabo zdravila Ruconest se posvetujte z zdravnikom.
No more than 2 doses, calculated according to step 7, should be given within 24 hours.
Skladno z izračunom iz 7. koraka v 24 urah ne smete prejeti več kot dveh odmerkov.
Scientific literature indicates an interaction of tissue-type plasminogen activator (tPA) and C1INH containing medicinal products.
Znanstvena literatura navaja medsebojno delovanje zdravil, ki vsebujejo tkivni aktivator plazminogena
What Ruconest looks like and contents of the pack
Izgled zdravila Ruconest in vsebina pakiranja
If you have prepared: - one vial with solution, draw up the volume as calculated - two vials and your bodyweight is below 84 kg, draw up in a similar way: a)14 ml from the first vial b) from the second vial, the difference between your calculated volume and the 14 ml from the first vial
- dve viali in je vaša telesna masa manj kot 84 kg, vbrizgajte na podoben način: a) 14 ml iz prve viale b) iz druge viale vbrizgajte razliko med vašo izračunano količino in 14 ml iz prve viale - dve viali in je vaša telesna masa več kot 84 kg, iz vsake viale vbrizgajte 14 ml v vsako brizgo
An additional dose of 50 U/kg was administered for 13/133 (10%) attacks.
Dodatni odmerek 50 e./kg je bil dan pri 13/133
If not used immediately in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2 to 8ºC, unless reconstitution has taken place in controlled and validated aseptic conditions.
24 ur pri temperaturi 2 ºC do 8 ºC, razen če je bila rekonstitucija opravljena v kontroliranih in validiranih aseptičnih pogojih.
• Necessary skills have to be acquired by non-Healthcare Professionals before Ruconest may be safely and effectively administered outside of a Healthcare Professional setting.
• Nezdravstveni delavec mora pred tem pridobiti potrebne spretnosti za varno in učinkovito dajanje zdravila Ruconest zunaj zdravstvene ambulante.
Skin and subcutaneous tissue disorders
Bolezni kože in podkožja koprivnica
Solvent for Ruconest Water for injections
vehikel za zdravilo Ruconest voda za injekcije
In case of an insufficient clinical response, an additional dose (50 U/kg body weight up to 4200 U) can be administered (see section 5.1).
V primeru nezadostnega kliničnega odziva se lahko da dodatni odmerek (50 e./kg telesne mase do 4200 e.) (glejte poglavje 5.1).
Ruconest is presented as a single glass vial containing a white to off-white powder for solution for injection.
Zdravilo Ruconest je pakirano kot ena steklena viala z belim do belkastim praškom za raztopino za injiciranje.
There are limited data on the use of this medicinal product in home- or self administration.
Podatkov o uporabi tega zdravila pri zdravljenju doma ali ob samostojnem dajanju je malo.
• Place the syringe on the work surface, taking care not to touch the surface or any other object with the syringe tip.
• Brizgo položite na delovno površino, pri čemer pazite, da se s konico brizge ne boste dotaknili površine ali katerega koli drugega predmeta.
• Hold this end with one hand, attach the syringe tip end and secure by turning clockwise until it stops.
• Ta konec držite z eno roko, namestite konico brizge in jo zavrtite v smeri urinega kazalca, da zaskoči.
• Position the tourniquet above the injection site - preferably the middle part of the upper arm.
• Žilno prevezo namestite nad mesto za injiciranje - če je mogoče, na sredo nadlakti.
The active substance is conestat alfa.
Zdravilna učinkovina je konestat alfa.
The effect of conestat alfa on the following target proteases was assessed in vitro: activated C1s, kallikrein, factor XIIa and factor XIa.
In vitro so ugotavljali učinek konestata alfa na naslednje tarčne proteaze: aktivirani C1, kalikrein,
• That Ruconest is derived from milk of transgenic rabbits and contains trace of rabbit proteins.
• Da je zdravilo Ruconest pridobljeno iz mleka transgenskih kuncev in vsebuje sledove kunčjih beljakovin.
100 U/kg n =13
100 e/kg n =13
Hepatic impairment may prolong the plasma half-life of conestat alfa, but this is not thought to be a clinical concern.
Kliničnih izkušenj z uporabo zdravila Ruconest pri bolnikih z jetrno okvaro ni. Jetrna okvara lahko podaljša plazemski razpolovni čas konestata alfa, vendar se meni, da to ni klinično pomembno.
If two syringes were prepared: fold over the tubing to prevent backflow, unscrew the empty syringe from the infusion set (counter clockwise) and immediately replace it with the second syringe.
Če sta pripravljeni dve brizgi: preganite cevko, da preprečite povratni tok, prazno brizgo odvijte s kompleta za infundiranje (zavrtite v smeri, ki je nasprotna vrtenju urinega kazalca) in jo nemudoma nadomestite z drugo brizgo.
• That Ruconest is contra indicated in all patients with known or suspected rabbit allergy.
• Da je zdravilo Ruconest kontraindicirano pri vseh bolnikih z znano alergijo na kunce ali sumom nanjo.
Once reconstituted, the product should be used immediately.
Po rekonstituciji je treba zdravilo takoj uporabiti.
- 2 adapters if 1 powder and 1 solvent vial is required - 4 adapters if 2 powder and 2 solvent vials are required
- 2 adapterja potrebujete v primeru 1 viale s praškom in 1 viale z vehiklom - 4 adapterje potrebujete v primeru 2 vial s praškom in 2 vial z vehiklom
• Put the adapter onto a powder vial, piercing the stopper, until it snaps onto the vial neck.
• Adapter nastavite na vialo s praškom, pritiskajte na zaporko, dokler ne zaskoči na vrat viale.
• Take a sterile syringe out of its packaging.
• Sterilno brizgo odstranite iz ovojnine.
There is no excretion, as conestat alfa is cleared from the circulation via receptor-mediated endocytosis followed by complete hydrolysis/degradation in the liver.
Izločanje Izločanja v obliki nespremenjenega konestata alfa ni, saj se konestat alfa očisti iz krvnega obtoka s presnovo v jetrih z od receptorja odvisno endocitozo, ki ji sledi popolna hidroliza/razgradnja.
• Fold down the yellow protection cap over the needle.
• Prek igle poveznite rumeni pokrovček.
• Remove the packaging from the adapter on the powder vial.
• Odstranite ovojnino z adapterja na viali s praškom.
Do not use this medicine if, after dissolving, you notice particles in the solution or if the solution is discolored.
Ne uporabljajte tega zdravila, če po raztapljanju raztopina spremeni barvo ali vsebuje delce.
Ruconest contains sodium (19.5 mg per vial)
Zdravilo Ruconest vsebuje natrij (19,5 mg na vialo)
Step 10: Preparation of the infusion set
10. korak: Priprava kompleta za infundiranje
Draw in 14 ml of solvent.
Izsesajte 14 ml vehikla.
Saline n = 13
Fiziološka raztopina n = 13
• 1 syringe
• 1 brizga
• date and time of the administration
• datum in čas injiciranja
• Push the solvent slowly, in a single motion, into the powder vial in order to minimise foaming.
• Z eno potezo vehikel počasi vbrizgajte v vialo s praškom, da v največji možni meri preprečite penjenje.
Hold the syringe with the tip pointing upwards and gently press the plunger to fill the infusion set with the solution.
Brizgo držite tako, da je konica obrnjena navzgor, in nežno pritisnite bat, da se komplet za infundiranje napolni z raztopino.
One administration kit contains:
En komplet za dajanje zdravila vsebuje:
Each vial of Ruconest (2100 U) should be reconstituted with 14 ml water for injections.
Rekonstitucija Vsako vialo zdravila Ruconest (2100 e.) se rekonstituira s 14 ml vode za injekcije.
Always use this medicine exactly as described in this leaflet or as your doctor or nurse have told you.
Pri uporabi tega zdravila natančno upoštevajte napotke v tem navodilu ali navodila zdravnika ali medicinske sestre.
Solvent vial: 20 ml of water for injections in a vial (type 1 glass) with a stopper (siliconized chlorobutyl rubber) and a flip-off seal (aluminium and coloured plastic).
Viala z vehiklom: 20 ml vode za injekcije v viali (steklo vrste 1) z zaporko (silikonizirana klorobutilna guma) in tesnilom »flip-off« (aluminij in barvna plastika).
• Carefully insert the needle of the infusion set, at the flattest possible angle, into the vein.
• Iglo iz kompleta za infundiranje pod najnižjim možnim kotom previdno vstavite v žilo.
Inject over about
Injiciranje v veno