natgillin/translations-raw huggingface dataset:
Therefore, it is considered appropriate to give a lower total dose of GONAL-f than generally used for urinary FSH, not only in order to optimise follicular development but also to minimise the risk of unwanted ovarian hyperstimulation.
Zato je primerno, da predpišemo nižji skupni odmerek zdravila GONAL-f kot se običajno uporablja za urinarni FSH, ne samo za optimiranje razvoja foliklov, ampak tudi zato, da čim bolj zmanjšamo tveganje za neželjeno hiperstimulacijo jajčnikov.
However the OHSS will only occur if hCG is also administered (see section 2, OHSS).
Vendar pa se lahko OHSS pojavi samo, če se uporabi tudi hCG (glejte poglavje 2, OHSS).
• If you have irregular periods, start using GONAL-f within the first 7 days of your menstrual cycle.
• Če imate neredne menstruacije, začnite uporabljati zdravilo GONAL-f v roku prvih 7 dni vašega menstruacijskega ciklusa.
Self-administration of GONAL-f should only be performed by patients who are well motivated, adequately trained and have access to expert advice.
Sami si lahko dajejo zdravilo GONAL-f samo bolniki, ki so dobro motivirani, ustrezno poučeni in imajo dostop do strokovnega nasveta.
Do not use GONAL-f if you notice any visible signs of deterioration, if the liquid contains particles or is not clear.
Ne uporabljajte zdravila GONAL-f, če opazite kakršne koli vidne znake kvarjenja, če tekočina vsebuje delce ali ni bistra.
Using your treatment diary to record your daily injection(s) allows you to verify every day that you received the full prescribed dose.
Uporaba dnevnika zdravljenja za beleženje dnevnih injiciranje vam omogoča potrditev, da ste vsak dan prejeli polni predpisani odmerek.
• Get a new needle - only use the "single-use" needles supplied.
• Vzemite novo iglo - uporabljajte samo igle za "enkratno uporabo".
Adherence to recommended GONAL-f dose and regimen of administration can minimise the risk of ovarian hyperstimulation (see sections 4.2 and 4.8).
Upoštevanje priporočenega odmerka zdravila GONAL-f in režima uporabe lahko zmanjšata tveganje hiperstimulacije jajčnikov (glejte poglavji 4.2 in 4.8).
The medicine must be administered immediately after preparation.
Zdravilo morate injicirati takoj po pripravi.
• Hold the dose knob down for a minimum of 5 seconds to ensure you inject the full dose (2).
• Gumb za odmerek držite navzdol vsaj 5 sekund, da injicirate celotni odmerek (2).
Warning: Medicine should not be disposed of via wastewater or household waste.
Opozorilo: Zdravila ne smete odvreči v odpadne vode ali med gospodinjske odpadke.
The effects of taking too much GONAL-f are unknown.
Učinki jemanja prevelike količine zdravila GONAL-f niso znani.
Studies have shown that co-administration with lutropin alfa, does not significantly alter the activity, stability, pharmacokinetic nor pharmacodynamic properties of the active substances.
Študije so pokazale, da sočasno dajanje z lutropinom alfa ne spreminja značilno aktivnosti, stabilnosti, farmakokinetičnih in farmakodinamičnih značilnosti učinkovin.
• Record this remaining dose in the ‘'Amount Set to Inject'' section in the next row (6).
• Zabeležite preostali odmerek v poglavje "Količina, nastavljena za injiciranje" v naslednji vrstici (6).
Push the plunger until the air bubbles are gone.
Potiskajte bat dokler zračni mehurčki ne izginejo.
If you are not sure, talk to your doctor before using this medicine.
Če ste negotovi, se posvetujte z zdravnikom preden uporabite to zdravilo.
Warning: If the Dose Feedback Window shows a number higher than 0, the GONAL-f pre-filled pen is empty and you have not received your full prescribed dose.
Opozorilo: Če je številka v okencu za prikaz odmerka večja od 0, to pomeni, da je GONAL-f napolnjen injekcijski peresnik prazen in da niste prejeli celega predpisanega odmerka.
Take as much time as you need to inject all the solution.
Vzemite si dovolj časa, da vbrizgate vso raztopino.
If severe OHSS occurs, it is recommended that gonadotropin treatment be stopped if still ongoing, and that the patient be hospitalised and appropriate therapy be started.
Če se pojavi hud OHSS, je priporočljivo zdravljenje z gonadotropinom ukiniti, v kolikor še traja, in bolnico sprejeti v bolnišnico in začeti ustrezno zdravljenje OHSS.
• Continue by pushing the capped needle against a firm surface until you hear a “click.”
• Nadaljujte s potiskanjem igle s pokrovčkom na čvrsto površino, dokler ne zaslišite "klika" (click).
Table: Results of study GF 8407 (randomised parallel group study comparing efficacy and safety of GONAL-f with urinary FSH in assisted reproduction technologies)
Preglednica: Zaključki preskušanja GF 8407 (randomizirano preskušanje z vzporednima skupinama pri katerem so primerjali učinkovitost in varnost zdravila GONAL-f z urinarnim FSH pri postopkih asistirane reprodukcije)
A commonly used regimen commences at 75-150 IU FSH daily and is increased preferably by 37.5 or 75 IU at 7 or preferably 14 day intervals if necessary, to obtain an adequate, but not excessive, response.
Režim, ki se običajno uporablja se začne z odmerkom 75-150 i.e. FSH na dan, in se ga, če je potrebno, povečuje za 37,5 ali 75 i.e. v 7 ali najbolje v 14 dnevnih intervalih, za doseganje zadostnega, a ne pretiranega odziva.
If you get lower abdominal pain, gain any weight rapidly, feel sick or are vomiting or if you have difficulty in breathing, talk to your doctor straight away who might ask you to stop using this medicine (see section 4).
Če se pojavijo bolečine v spodnjem delu trebuha, če hitro pridobite telesno maso, če vam je slabo ali bruhate ali imate težave z dihanjem, se takoj pogovorite z zdravnikom, ki vam bo lahko priporočil prekinitev zdravljenja (glejte poglavje 4).
Women with anovulation resulting from severe LH and FSH deficiency.
Ženske z anovulacijo zaradi hudega pomanjkanja LH in FSH.
If you notice any of the above-listed side effects you should immediately contact your doctor who might ask you to stop using GONAL-f.
Če opazite katerega koli od zgoraj navedenih neželenih učinkov, se takoj posvetujte z zdravnikom, ki vam bo morda predlagal, da prenehate uporabljati zdravilo GONAL-f.
• GONAL-f dose may be increased, depending on your response.
• Odmerek zdravila GONAL-f se lahko zviša glede na vaš odziv.
4.7 Effects on ability to drive and use machines GONAL-f is expected to have no or negligible influence on the ability to drive and use machines.
4.7 Vpliv na sposobnost vožnje in upravljanja strojev Pričakuje se, da zdravilo GONAL-f nima vpliva ali ima zanemarljiv vpliv na sposobnost vožnje in upravljanja strojev.
The prepared solution is for your use alone and must not be given to other patients.
Pripravljena raztopina je samo za vašo uporabo in se ne sme injicirati drugim bolnikom.
Follitropin alfa is a type of “Follicle Stimulating Hormone” (FSH) which belongs to the family of hormones called “gonadotropins”.
Folitropin alfa je vrsta "folikle stimulirajočega hormona" (FSH), ki spada v skupino hormonov, ki se imenujejo "gonadotropini".
Patients with porphyria or a family history of porphyria should be closely monitored during treatment with GONAL-f.
Bolnike s porfirijo ali s porfirijo v družinski anamnezi moramo med zdravljenjem z zdravilom GONAL-f skrbno nadzorovati.
Women with anovulation (including polycystic ovarian syndrome) GONAL-f may be given as a course of daily injections.
Ženske z anovulacijo (vključno s sindromom policističnih jajčnikov) Zdravilo GONAL-f se lahko daje kot zaporedje dnevnih injekcij.
B. CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Medicinal product subject to restricted medical prescription (See Annex I: Summary of Product Characteristics, section 4.2)
B. POGOJI ALI OMEJITVE GLEDE OSKRBE IN UPORABE Predpisovanje in izdaja zdravila je le na recept s posebnim režimom (glejte Prilogo I: Povzetek glavnih značilnosti zdravila, poglavje 4.2).
If your doctor decides to try GONAL-f treatment, to monitor the treatment, they may ask you to provide semen for analysis 4 to 6 months after starting treatment.
Če se zdravnik odloči, da vas bo poskusil zdraviti z zdravilom GONAL-f, vas bo za spremljanje vašega zdravljenja, 4 do 6 mesecev po začetku zdravljenja, prosil za vzorce sperme za analizo.
The effects of an overdose of GONAL-f are unknown, nevertheless, there is a possibility that OHSS may occur (see section 4.4).
Učinki prevelikega odmerka zdravila GONAL-f niso znani, vendar pa obstaja možnost, da se pojavi OHSS (glejte poglavje 4.4).
• If you are a man: with damaged testicles that cannot be healed.
• če ste moški: z nepopravljivo poškodbo testisov.
• gynaecological haemorrhages of unknown aetiology
• ginekološka krvavitev neznane etiologije
• Never reuse any used needle.
• Nikoli ponovno ne uporabite že uporabljene igle.
This instructions for use was last revised in:
»Navodilo za uporabo« je bilo nazadnje revidirano dne:
• Serious blood clotting complications (thromboembolic events) sometimes independent of OHSS may be found very rarely (may affect up to 1 in 10,000 people).
• Resni zapleti zaradi krvnih strdkov (trombembolični dogodki), ki so včasih neodvisni od OHSS, so zelo redki (prizadenejo lahko največ 1 od 10.000 bolnikov).
• The solvent contains water for injections and benzyl alcohol.
• Vehikel vsebuje vodo za injekcije in benzilalkohol.
GONAL-f is indicated for use in infertility (see section 4.1).
Zdravilo GONAL-f je indicirano za uporabo pri neplodnosti (glejte poglavje 4.1).
• 2 alcohol swabs
• 2 alkoholni blazinici
• Immediately inject the solution: Your doctor or nurse will have already advised you where to inject (e.g. tummy, front of thigh).
• Takoj injicirajte raztopino: Vaš zdravnik ali medicinska sestra sta vam že svetovala, kje dati injekcijo (npr. v trebuh, sprednjo stran stegna).
Your doctor will have told you how many IUs to inject each day.
Vaš zdravnik vam bo povedal, koliko i.e. si morate vsak dan injicirati.
• Complications of OHSS such as twisting of ovaries or blood clotting may occur rarely (may affect up to 1 in 1,000 people).
• Zapleti OHSS, kot je torzija jajčnikov ali nastajanje krvnih strdkov, se pojavijo redko (prizadene lahko največ 1 od 1.000 bolnikov).
In rabbits, the formulation reconstituted with 0.9 % benzyl alcohol and 0.9 % benzyl alcohol alone, both resulted in a slight haemorrhage and subacute inflammation after single subcutaneous injection or mild inflammatory and degenerative changes after single intramuscular injection respectively.
Pri zajcih sta tako pripravek rekonstituiran z 0,9 % benzilalkoholom kot sam 0,9 % benzilalkohol povzročila rahlo krvavitev in subakutno vnetje po enkratni subkutani injekciji oziroma blago vnetje in degenerativne spremembe po enkratni intramuskularni injekciji.
• Inject under the skin by pushing gently the plunger, as you were taught.
• Z nežnim pritiskanjem na bat injicirajte pod kožo, kot so vas naučili.
When undergoing assisted reproductive technology or stimulation of your ovaries to produce eggs, you are more likely to have a miscarriage than the average woman.
Pri tehnikah asistirane reprodukcije ali stimulacije jajčnikov za tvorbo jajčec je verjetnost splava večja kot pri povprečnih ženskah.
(If you have been prescribed more than one vial of GONAL-f, slowly re-inject the solution into another powder vial, until you have the prescribed number of powder vials dissolved in the solution.
(Če vam je zdravnik predpisal več kot eno vialo zdravila GONAL-f, počasi ponovno injicirajte raztopino v drugo vialo s praškom, dokler v raztopini ne raztopite predpisanega števila vial s praškom.
Dial your prescribed dose.
Izberete svoj predpisani odmerek.
Get together everything you need and lay them out:
Pripravite in razvrstite vse kar potrebujete:
This may indicate that the ovaries over-reacted to the treatment and that large ovarian cysts developed (see also in section 2. under “Ovarian HyperStimulation Syndrome”).
Lahko kažejo na to, da so se jajčniki premočno odzvali na zdravljenje in so se razvile velike ciste na jajčnikih (glejte tudi poglavje 2 "Sindrom hiperstimulacije jajčnikov (OHSS)").
In adult women
Pri odraslih ženskah
Removing air bubbles
Odstranjevanje zračnih mehurčkov
The following table states the volume to be administered to deliver the prescribed dose:
V naslednji tabeli so navedeni volumni, ki se aplicirajo za zagotovitev predpisanega odmerka:
GONAL-f should not be used when an effective response cannot be obtained.
Zdravila GONAL-f se ne sme uporabiti, če ni mogoče doseči učinkovitega odziva.
• fibroid tumours of the uterus incompatible with pregnancy
• fibroidni tumorji maternice, ki niso združljivi z nosečnostjo
• Draw up some air into the syringe by pulling the plunger to approximately the 1 mL mark.
• Povlecite v brizgo malo zraka s potegom bata približno do oznake 1 ml.
GONAL-f should be given at a dose of 150 IU three times a week, concomitantly with hCG, for a minimum of 4 months.
Zdravilo GONAL-f se mora dajati v odmerku 150 i.e., trikrat na teden, sočasno s hCG, najmanj 4 mesece.
• After a minimum of 5 seconds, pull the needle out of the skin while keeping the dose setting knob pressed down (3).
• Po vsaj 5 sekundah izvlecite iglo iz kože in še vedno držite pritisnjen gumb za nastavitev odmerka (3).
Removing the needle after each injection.
Odstranjevanje injekcijske igle po vsakem injiciranju
• Do not use any GONAL-f solution left in the vial after 28 days.
• Ne uporabite raztopine zdravila GONAL-f, ki po 28 dneh ostane v viali.
In a commonly used protocol, GONAL-f is started approximately 2 weeks after the start of agonist treatment, both being continued until adequate follicular development is achieved.
Po protokolu, ki se splošno uporablja, se zdravljenje z zdravilom GONAL-f začne približno 2 tedna po začetku zdravljenja z agonistom in se nadaljuje z dajanjem obeh zdravil, dokler ni dosežen zadosten folikularni razvoj.
Amount Displayed After Injection
Količina, prikazana po injiciranju
GONAL-f is a potent gonadotrophic substance capable of causing mild to severe adverse reactions, and should only be used by physicians who are thoroughly familiar with infertility problems and their management.
Zdravilo GONAL-f je močna gonadotropna učinkovina, ki lahko povzroči blage do hude neželene reakcije in jo zato smejo uporabljati samo zdravniki, ki dobro poznajo težave neplodnosti in njihovo obvladovanje.
• Your doctor or nurse will show you how to inject GONAL-f before you can inject yourself.
• Vaš zdravnik ali medicinska sestra vam bosta pokazala kako se injicira zdravilo GONAL-f, preden si ga boste lahko injicirali sami.
The pH of the solution is 6.7-7.3.
pH raztopine je 6,7 do 7,3.
Warning: Please read these instructions for use before using your GONAL-f pre-filled pen.
Opozorilo: Ta navodila preberite pred uporabo GONAL-f napolnjenega injekcijskega peresnika.
Thromboembolism (both in association with and separate from OHSS)
trombembolizem (tako v povezavi z OHSS in nepovezano z njim)
Safety, efficacy and pharmacokinetics of GONAL-f in patients with renal or hepatic impairment have not been established.
Varnost, učinkovitost in farmakokinetika zdravila GONAL-f pri bolnikih z ledvično ali jetrno okvaro niso bili dokazani.
For instructions on the reconstitution and administration of GONAL-f powder and solvent for solution for injection see section 6.6 and the package leaflet.
Za navodila glede rekonstitucije in dajanja zdravila GONAL-f prašek in vehikel za raztopino za injiciranje glejte poglavje 6.6 in navodilo za uporabo.
If you had in the past or recently blood clots in the leg or in the lung, or a heart attack or stroke, or if those happened in your family, then you might have a higher risk that these problems occur or become worse with GONAL-f treatment.
Težave s strjevanjem krvi (trombembolični dogodki) Če ste pred kratkim ali v preteklosti imeli krvne strdke v nogah ali v pljučih, srčni napad ali kap, ali če se je to zgodilo kakemu družinskemu članu, je morda pri vas večje tveganje, da se te težave pri zdravljenju z zdravilom GONAL-f pojavijo ali poslabšajo.
In case of exposure during pregnancy, clinical data are not sufficient to exclude a teratogenic effect of GONAL-f.
Klinični podatki pri nosečnicah, izpostavljenih zdravilu, ne zadoščajo za izključitev teratogenih učinkov zdravila GONAL-f.
Treatment with GONAL-f should be initiated under the supervision of a physician experienced in the treatment of fertility disorders.
Zdravljenje z zdravilom GONAL-f se mora začeti pod nadzorom zdravnika, ki ima izkušnje z zdravljenjem motenj plodnosti.
• An empty syringe for injection (see illustration below)
• 1 prazno injekcijsko brizgo za injiciranje (glejte sliko spodaj)
Dispose of all used items: Once you have finished your injection, immediately discard all needles and empty glass containers safely preferably in the sharp container.
Odstranite vse uporabljene predmete: Ko ste zaključili z injiciranjem, takoj varno zavrzite vse injekcijske igle in prazne steklene vsebnike, najbolje v posodo za ostre predmete.
Contains: 1 mL water for injections
Vsebuje: 1 ml vode za injekcije.
ONLY check for drop(s) the FIRST TIME you use a new GONAL-f pre-filled pen to remove air in the system.
Kaplje preverite LE PRVIČ, ko uporabljate nov GONAL-f napolnjeni injekcijski peresnik, da iz sistema odstranite zrak.
Therefore, if signs of ovarian hyperstimulation occur such as serum oestradiol level > 5,500 pg/mL or > 20,200 pmol/L and/or ≥ 40 follicles in total, it is recommended that hCG be withheld and the patient be advised to refrain from coitus or to use barrier contraceptive methods for at least 4 days.
Zato je v primeru pojava znakov hiperstimulacije jajčnikov, kot so ravni estradiola v serumu > 5.500 pg/ml ali > 20.200 pmol/l in/ali skupno ≥ 40 foliklov, priporočljivo, da se opusti dajanje hCG in se bolnici svetuje, da se vzdrži spolnih odnosov ali uporablja mehanska kontracepcijska sredstva najmanj 4 dni.
• Set the dose to the missing amount you recorded in the treatment diary or the number still displayed in the Dose Feedback Window on your previous pen, and inject.
• Nastavite odmerek na manjkajočo količino, ki ste jo zabeležili v dnevnik zdravljenja, ali številko, prikazano v okencu za prikaz odmerka predhodnega napolnjenega injekcijskega peresnika, in injicirajte.
• The OHSS may become severe with clearly enlarged ovaries, decreased urine production, weight gain, difficulty in breathing and/or possible fluid accumulation in your stomach or chest.
• OHSS lahko postane resen z izrazito povečanimi jajčniki, zmanjšanim nastajanjem urina, s pridobivanjem telesne mase, težavami dihanja in/ali morebitnim nabiranjem tekočine v trebuhu ali prsnem košu.
Throw it away in a sharps disposal container.
Zavrzite ga v vsebnik za odlaganje ostrih odpadkov.
Individual reconstituted vials should be for single patient use only.
Posamične rekonstituirane viale so namenjene za uporabo pri samo enem bolniku.
The pH of the reconstituted solution is 6.5-7.5.
pH rekonstituirane raztopine je 6,5 do 7,5.
Up to three containers of powder may be dissolved in 1 mL of solvent.)
Do tri vsebnike s praškom lahko raztopite v 1 ml vehikla.)
Swirl gently without removing the syringe.
Nežno obračajte, ne da bi odstranili injekcijsko brizgo.
Water for injections Benzyl alcohol
Vehikel voda za injekcije benzilalkohol
When undergoing assisted reproductive technology the risk of having a multiple pregnancy is related to your age, the quality and the number of fertilised eggs or embryos placed inside you.
Pri uporabi tehnik asistirane reprodukcije je tveganje za večplodno nosečnost povezano z vašo starostjo in kakovostjo ter številom oplojenih prenesenih jajčec ali embrijev.
In women, safe and effective use of GONAL-f calls for monitoring of ovarian response with ultrasound, alone or preferably in combination with measurement of serum oestradiol levels, on a regular basis.
Pri ženskah je za varno in učinkovito uporabo zdravila GONAL-f potrebno redno nadzorovanje odziva jajčnikov z ultrazvokom ali še bolje z ultrazvokom v kombinaciji z merjenjem serumskih ravni estradiola.
If you are not ovulating and have irregular or no periods.
Če nimate ovulacije in imate neredne menstruacije ali menstruacij nimate
• If you administer GONAL-f to yourself, please carefully read and follow the “Instructions for
• Če si zdravilo GONAL-f dajete sami, skrbno preberite in upoštevajte "Navodilo za uporabo".
Nevertheless one could expect Ovarian Hyper-Stimulation Syndrome (OHSS) to occur, which is described in section 4.
Vendar pa lahko pričakujemo pojav sindroma hiperstimulacije jajčnikov (Ovarian Hyper-Stimulation Syndrome - OHSS), ki je podrobno opisan v poglavju 4.
Getting your GONAL-f pre-filled pen ready for injection 4.1.
Priprava vašega GONAL-f napolnjenega injekcijskega peresnika za injiciranje 4.1.
• Repeat Section 3 (“Before you start using your GONAL-f pre-filled pen “) through Section 4 (“Getting your GONAL-f pre-filled pen ready for injection“) with a second pen.
• Ponovite poglavje 3 ("Preden začnete uporabljati svoj GONAL-f napolnjeni injekcijski peresnik") do poglavja 4 ("Priprava vašega GONAL-f napolnjenega injekcijskega peresnika za injiciranje") z drugim napolnjenim injekcijskim peresnikom.
Comparative clinical studies have shown that on average patients require a lower cumulative dose and shorter treatment duration with GONAL-f compared with urinary FSH.
Primerjalna klinična preskušanja so pokazala, da potrebuje bolnik v povprečju nižji skupni odmerek in krajše trajanje zdravljenja z zdravilom GONAL-f kot z urinarnim FSH.
• Take the syringe for injection and fill it with air by pulling the plunger to the correct dose in International Units (IU FSH).
• Vzemite brizgo za injiciranje in jo napolnite z zrakom tako, da bat potegnete do pravega odmerka v mednarodnih enotah (i.e. FSH).
What GONAL-f is and what it is used for What you need to know before you use GONAL-f How to use GONAL-f
Kaj je zdravilo GONAL-f in za kaj ga uporabljamo Kaj morate vedeti, preden boste uporabili zdravilo GONAL-f Kako uporabljati zdravilo GONAL-f
• If you see a tiny drop(s) of fluid proceed to Section 5: Setting the dose prescribed by your doctor.
• Če vidite majhne kaplje tekočine, nadaljujte s poglavjem 5: Nastavitev odmerka, ki ga je predpisal zdravnik.
• The dose number shown in the Dose Feedback Window will turn back to 0.
• Številka, prikazana v okencu za prikaz odmerka, se vrne na 0.
• For further injections with the prepared solution of GONAL-f, repeat steps 4. to 7.
• Za sledeča injiciranja pripravljene raztopine zdravila GONAL-f ponovite korake od točke 4 do
Safety and effectiveness of GONAL-f in elderly patients have not been established.
Varnost in učinkovitost zdravila GONAL-f pri starejših bolnikih nista bili dokazani.
When using GONAL-f, you have a higher risk of being pregnant with more than one child at the same time (“multiple pregnancy”, mostly twins), than if you conceived naturally.
Pri uporabi zdravila GONAL-f je tveganje za nosečnost z več plodi večja ("večplodna nosečnost", običajno dvojčki) kot pri naravni zanositvi.
• The numbers on the Dose Feedback Window are measured in International Units or IUs.
• Številke v oknu za prikaz odmerka so v mednarodnih enotah ali i.e.
•Gather everything you need and lay it out:
• Pripravite in zložite vse potrebno:
Such patients are unresponsive to GONAL-f/hCG therapy.
Takšni bolniki se na zdravljenje z zdravilom GONAL-f/hCG ne odzivajo.
• Anovulation (including polycystic ovarian syndrome) in women who have been unresponsive to treatment with clomiphene citrate.
• Anovulacija (vključno s sindromom policističnih jajčnikov) pri ženskah, ki se niso odzvale na zdravljenje s klomifen citratom.
Luteal phase support may be considered since lack of substances with luteotrophic activity (LH/hCG) after ovulation may lead to premature failure of the corpus luteum.
Podpora lutealne faze je morda potrebna, ker lahko pomanjkanje snovi z luteotropnim učinkom (LH/hCG) po ovulaciji vodi do prezgodnje odpovedi rumenega telesca.