natgillin/translations-raw huggingface dataset:
The prevalence of acquired resistance may vary geographically and with time for selected species and local information on resistance is desirable, particularly when treating severe infections.
Prevalenca pridobljene odpornosti se lahko za izbrane vrste razlikuje geografsko in časovno.
The combination of vancomycin with a cephalosporin has a synergistic effect against some oxacillin-resistant Staphylococcus epidermidis strains, and the combination of vancomycin with rifampicin has a synergistic effect against Staphylococcus epidermidis and a partial synergistic effect against some Staphylococcus aureus strains.
Kombinacija vankomicina s cefalosporini ima sinergističen učinek proti nekaterim na oksacilin odpornih sevom Staphylococcus epidermidis, kombinacija vankomicina z rifampicinom pa ima sinergističen učinek na Staphylococcus epidermidis in delno sinergističen učinek pri nekaterih sevih Staphylococcus aureus.
Significantly increased doses may be required to achieve therapeutic serum concentrations in pregnant women (see Section 4.6).
Pri nosečnicah bo za doseganje terapevtske koncentracije v serumu morda treba precej povečati odmerek (glejte poglavje 4.6).
4 to 6 weeks*
4 do 6 tednov*
Model-based methods may be useful in the prediction of individual dose requirements to reach an adequate AUC.
Pri določevanju, kakšna velikost odmerka je pri posamezniku potrebna, da bi dosegli ustrezen AUC, lahko uporabimo metode na podlagi modeliranja.
Cross-resistance with other glycopeptide antibiotics, such as teicoplanin, does occur.
Včasih pride do navzkrižne odpornosti med drugimi glikopeptidnimi antibiotiki, kot je teikoplanin.
Administration site related reactions
Reakcije na mestu uporabe
Drug interactions with anaesthetic agents
Interakcije zdravila z anestetiki
Minimum inhibitory concentration breakpoints established by the European Committee on Antimicrobial Susceptibility Testing (EUCAST) are as follows:
Mejne vrednosti, ki temeljijo na testih Evropskega odbora za preskušanje za protimikrobne občutljivosti (EUCAST):
Lower maintenance doses may be required due to the age-related reduction in renal function.
Pri starejših bolnikih bo morda treba zmanjšati odmerke zdravila zaradi zmanjšanega delovanja ledvic.
The most common adverse reactions are phlebitis, pseudo-allergic reactions and flushing of the upper body (“red-neck syndrome”) in connection with too rapid intravenous infusion of vancomycin.
Najpogostejši neželeni učinki so flebitis, psevdoalergijske reakcije, pordelost zgornjega dela telesa (»sindrom rdečega moža«) pri prehitrem intravenskem infundiranju vankomicina.
Vancomycin should be used with care in patients with renal insufficiency, including anuria, as the possibility of developing toxic effects is much higher in the presence of prolonged high blood concentrations.
Pri bolnikih z ledvično insufienco, vključno z anurijo, je treba vankomicin uporabljati previdno, sa je verjetnost za razvoj toksičnih učinkov ob dolgotrajno visokih koncentracijah veliko večja.
In obese patients, the initial dose should be individually adapted according to total body weight as in non-obese patients.
Pri bolnikih s prekomerno telesno maso je treba začetni odmerek prilagoditi posamezniku glede na skupno telesno maso, tako kot pri bolnikih z normalno telesno maso.
Vancomycin is a tricyclic glycopeptide antibiotic that inhibits the synthesis of the cell wall in sensitive bacteria by binding with high affinity to the D-alanyl-D-alanine terminus of cell wall precursor units.
Vankomicin je triciklični glikopeptidni antibiotik, ki zavira sintezo celične stene občutljivih bakterij, tako da se z veliko afiniteto veže na D-alanil-D-alaninski konec prekurzorskih enot celične stene.
The frequency of therapeutic drug monitoring (TDM) needs to be individualized based on the clinical situation and response to treatment, ranging from daily sampling that may be required in some hemodynamically unstable patients to at least once weekly in stable patients showing a treatment response.
Pri nekaterih hemodinamično nestabilnih bolnikih je lahko potrebno vsakodnevno vzorčenje, pri hemodinamično stabilnih bolnikih, ki se odzivajo na zdravljenje, pa lahko zadošča preverjanje vsaj enkrat na teden.
What Vancomycin is and what it is used for
Kaj je zdravilo [Ime zdravila] in za kaj ga uporabljamo
Vancomycin should be used with caution in patients with allergic reactions to teicoplanin, since cross hypersensitivity, including fatal anaphylactic shock, may occur.
Pri bolnikih z alergijskimi reakcijami na teikoplanin moramo biti previdni pri uporabi vankomicina, saj lahko pride do navzkrižne preobčutljivosti, tudi do usodnega anafilaktičnega šoka.
Ototoxicity has primarily been reported in patients given high doses, or in those on concomitant treatment with other ototoxic medicinal product like aminoglycoside, or in those who had a preexisting reduction in kidney function or hearing.
O ototoksičnosti poročajo predvsem pri bolnikih, ki so dobili velike odmerke, ali pri tistih, ki so jih hkrati zdravil z drugimi ototoksičnimi zdravili, kot je aminoglikozid, ali pri tistih, ki so pred zdravljenem imeli težave z zmanjšanim delovanjem ledvic ali s sluhom.
Pseudomembranous enterocolitis
Psevdomembranski enterokolitis
Vancomycin is used in adults and adolescents from 12 years of age for the treatment of infections of the mucosa of the small and the large intestines with damage to the mucosae (pseudomembranous colitis), caused by the Clostridium difficile bacterium.
Vankomicin uporabljamo pri odraslih in mladostnikih, starejših od 12 let, za zdravljenje okužb sluznice tankega in debelega črevesa s poškodbami sluznice (psevdomembranski kolitis), ki so posledice bakterije Clostridium difficile.
Continuous infusion: loading dose of 1000 mg/L per litter of dialysate followed by 25 mg/L (after 3-6 h of loading dose) in all exchanges.
Kontinuirana infuzija: začetni odmerek je 1000 mg/l na liter dializata, ki mu sledi 25 mg/l (3-6 ur po začetnem odmerku) v vseh menjavah.
NAME OF THE MEDICINAL PRODUCT [For all vancomycin 125 mg capsule] <{(Invented) vancomycin 125mg capsule}> [For all vancomycin 250 mg capsule] <{(Invented) vancomycin 250mg capsule}>
IME ZDRAVILA [Za vse kapsule vankomicina 125 mg] <{(Izmišljeno ime) 125 mg kapsule}> [Za vse kapsule vankomicina 250 mg] <{(Izmišljeno ime) 250 mg kapsule}>
The absorption of vancomycin from the gastrointestinal tract is negligible.
Absorpcija vankomicina iz prebavnega sistema je zanemarljiva.
During or shortly after rapid infusion anaphylactic/anaphylactoid reactions including wheezing may occur.
Med ali kmalu po hitri infuziji lahko pride do anafilaktičnih ali anafilaktoidnih reakcij, tudi do piskajočega dihanja.
During anaesthesia, doses must be well diluted and administered slowly with close cardiac monitoring.
Med anestezijo mora biti odmerek močno razredčen in treba ga je dovajati počasi.
In case of severe persistent diarrhoea the possibility of pseudomembranous enterocolitis that might be life-threatening has to be taken into account (see section 4.8).
V primeru dolgotrajne hude driske lahko pride do smrtno nevarnega psevdomembranskega enterokolitisa (glejte poglavje 4.8).
When using for the treatment of infections related to peritoneal dialysis, your doctor will decide exactly how much vancomycin you need.
Pri zdravljenju okužb, povezanih s peritonealno dializo, vam bo zdravnik predpisal primeren odmerek vankomicina.
Depending on the clinical situation, consideration could be given to withhold the next dose while awaiting the results of vancomycin levels.
Od kliničnega stanja je odvisno, ali se bomo odločili počakati z naslednjim odmerkom, dokler ne izvemo vrednosti za vankomicin v serumu.
In neonates, after intravenous administration, vancomycin volume of distribution varies between 0.38 and 0.97 L/kg, similar to adult values, while clearance varies between 0.63 and 1.4 ml/kg/min.
Pri novorojenčkih, po intravenski uporabi, se volumen porazdelitve giblje med 0,38 in 0,97 l/kg, kar so podobne vrednosti kot pri odraslih.
Stopping the infusion usually results in a prompt cessation of these reactions.
Te reakcije običajno takoj izginejo, če ustavite injiciranje.
Vancomycin pharmacokinetics is not altered in patients with hepatic impairment.
Farmokinetika vankomicina pri bolnikih z okvaro jeter ni spremenjena.
[For parenteral formulations authorised for intraperitoneal use:] - In patients receiving peritoneal dialysis, vancomycin is used in adults and children for the treatment of infections related to peritoneal dialysis.
[Za parenteralna zdravila, odobrena za intraperitonealno uporabo:] - Pri bolnikih, odraslih in otrocih, ki prejemajo peritonealno dializo, zdravimo okužbe, povezane s peritonealno dializo.
Synergism
Sinergizem
This may be associated with a high fever and joint pains - Cardiac arrest - Inflammation of the bowel which causes abdominal pain and diarrhea, which may contain blood Not known (frequency cannot be estimated from the available data): - Being sick (throwing up), diarrhoea - Confusion, drowsiness, lack of energy, swelling, fluid retention, decreased urine - Rash with swelling or pain behind the ears, in the neck, groin, under the chin and armpits (swollen lymph nodes), abnormal blood and liver function tests - Rash with blisters and fever.
To lahko spremljajo visoka vročina in bolečine v sklepih - srčni zastoj - vnetje črevesja z bolečinami v trebuhu in drisko, v blatu se lahko pojavi kri Neznana pogostnost (pogostnosti iz razpoložljivih podatkov ni mogoče ugotoviti): - bruhanje, driska - zbeganost, dremavost, pomanjkanje energije, zatekanje, zastajanje tekočine, manj pogosto uriniranje - izpuščaj z oteklino ali bolečino za uhlji, v vratu, dimljah, pod brado in pazduhami (otečene bezgavke), nenormalni izvidi krvi in delovanja jeter - izpuščaj z mehurji in vročina
- Necrotizing
-nekrotizirajoče
Cardiac disorders Very rare
Srčne bolezni: Zelo redko srčni zastoj
15 mg/kg
15 mg/kg na 24 ur
Pregnancy
Nosečnice
Adults and adolescents (from 12 years and older) The dosage will be calculated according to your body weight.
Uporaba pri odraslih in otrocih, starejših od 12 let Odmerek bodo izračunali glede na vašo telesno maso.
Drug fever, shivering, Pain and muscle spasm of the chest and back muscles
Redki z zdravilom povzročena vročina, drgetanje, bolečina in krči v mišicah prsi in hrbta
Preterm and term newborn infants (from 0 to 27 days) The dosage will be calculated according to post-menstrual age (time elapsed between the first day of the last menstrual period and birth (gestational age) plus the time elapsed after birth (post-natal age).
Odmerek bo izračunan glede na postmenstrualno starost (čas od prvega dne zadnje menstruacije do rojstva (gestacijska starost) plus čas po rojstvu (postnatalna starost)).
Vancomycin powder is made into a <solution for infusion> <or> <oral solution>.
Vankomicin je prašek, iz katerega pripravimo <raztopino za infundiranje><ali><peroralno raztopino.>
Vancomycin capsules are indicated in patients 12 years and older for the treatment of Clostridium difficile infection (CDI) (see sections 4.2, 4.4 and 5.1).
Vankomicin v obliki kapsul je primeren za zdravljene bolnikov, starejših od 12 let, pri okužbah z bakterijo Clostridium difficile (CDI, Clostridium difficile infection) (glejte poglavja 4.2, 4.4 in 5.1).
Oral Use Only
Samo za peroralno uporabo
One possible way of dosing vancomycin in neonates is illustrated in the following table: (see section 4.4)
Primer odmerjanja vankomicina pri novorojenčkih je prikazan v spodnji preglednici: (glejte poglavje
When vancomycin is administered parenterally, the most common adverse reactions are phlebitis, pseudo-allergic reactions and flushing of the upper body (“red-neck syndrome”) in connection with too rapid intravenous infusion of vancomycin.
Pri parenteralni uporabi vankomicina so najbolj pogosti neželeni učinki flebitis, psevdoalergijske reakcije in pordelost zgornjega dela telesa (»sindrom rdečega vratu«) pri prehitrem intravenskem infundiranju vankomicina.
Vancomycin should not be administered intramuscularly due to the risk of necrosis at the site of administration.
Vankomicina ne smemo vnesti intramuskularno, saj lahko pride do nekroze na mestu vnosa.
2 - Strictly follow the prescription.
1 - atibiotike uporabljajte le, če vam jih predpiše zdravnik 2 - natančno upoštevajte recept
No dose adjustment is needed in patients with hepatic insufficiency.
Pri bolnikih z okvarjenim delovanjem jeter prilagoditev odmerkov ni potrebna.
Concomitant administration of vancomycin and anaesthetic agents has been associated with erythema and histamine-like flushing in children.
Hkratna uporaba vankomicina in anestetikov pri otrocih lahko povzroči eritem in odzive, podobne histaminskemu.
- Being sick (throwing up), diarrhoea - Confusion, drowsiness, lack of energy, swelling, fluid retention, decreased urine - Rash with swelling or pain behind the ears, in the neck, groin, under the chin and armpits (swollen lymph nodes), abnormal blood and liver function tests - Rash with blisters and fever.
- zbeganost, dremavost, pomanjkanje energije, zatekanje, zastajanje tekočine, manj pogosto uriniranje - izpuščaj z oteklino ali bolečino za uhlji, v vratu, dimljah, pod brado in pazduhami (otečene bezgavke), nenormalni izvidi krvi in delovanja jeter - izpuščaj z mehurji in vročina
In patients on intermittent haemodialysis, vancomycin levels should be usually obtained before the start of the haemodialysis session.
Pri bolnikih na intermitentni hemodializi je treba raven vankomicina preveriti pred začetkom naslednje hemodialize.
Hypersensitivity to the active substance or to any of the excipients (see section 4.4).
4.3 Kontraindikacije Preobčutljivost za vankomicin ali katero koli pomožno snov (glejte poglavje 4.4).
However, if you have an inflammatory disorder of the digestive tract, especially if you also have a kidney disorder, similar side effects as those that occur when vancomycin is given by infusion may appear.
Če pa imate vnetno bolezen prebavil, še posebej če imate hkrati tudi motnje v delovanju ledvic, lahko pride do podobnih neželenih učinkov kot pri vankomicinu, ki ga dobite v obliki infuzije.
Vancomycin is administered intravenously for the treatment of systemic infections.
Za zdravljenje sistemskih okužb vankomicin uporabimo intravensko.
Serial monitoring of renal function should be performed when treating patients with underlying renal dysfunction or patients receiving concomitant therapy with an aminoglycoside or other nephrotoxic drugs.
Treba je redno preverjati delovanje ledvic pri bolnikih z okvarjenim delovanjem ledvic in pri bolnikih, ki imajo hkrati terapijo z aminoglikozidom ali drugimi nefrotoksičnimi zdravili.
Renal function must be taken into consideration for subsequent doses and interval of administration.
Pri nadaljnjih odmerkih in določanju intervalov med odmerki je treba upoštevati ledvično funkcijo.
Vancomycin should be used with particular care in premature neonates and young infants, because of their renal immaturity and the possible increase in the serum concentration of vancomycin.
Vankomicin je treba uporabljati še posebej previdno pri nedonošenčkih in dojenčkih, saj še nimajo povsem razvitih ledvic in obstaja verjetnost za zvišanje ravni vankomicina v serumu.
[For parenteral formulations authorised for intraperitoneal use:] Intraperitoneal administration
[Za parenteralna zdravila, odobrena za intraperitonealno uporabo:] Intraperitonealna uporaba
No blood concentrations were detected and urinary recovery did not exceed
V krvi niso našli sledi zdravila, v urinu pa delež učinkovine ni presegel 0,76%.
[For parenteral formulations authorised for oral use:] The absorption of vancomycin from the gastrointestinal tract is negligible.
[Za parenteralna zdravila, odobrena za peroralno uporabo:] Prevzem vankomicina iz prebavnega sistema v telo je zanemarljiv.
Oral vancomycin use increases the chance of vancomycin-resistant Enterococci populations in the gastrointestinal tract.
Pri peroralni uporabi vankomicina se poveča tveganje za namnožitev na vankomicin odpornoh populacij enterokokov v prebavnem sistemu.
Vancomycin is active against gram-positive bacteria, such as staphylococci, streptococci, enterococci, pneumococci, and clostridia.
Vankomicin je učinkovit proti po Gramu pozitivnih bakterijam, kot so stafilokoki, streptokoki, enterokoki, pnevmokoki in klostridij.
Peritoneal dialysis-associated peritonitis
Peritonitis zaradi peritonealne dialize
After oral administration, monitoring vancomycin serum concentrations in patients with inflammatory intestinal disorders should be performed (see section 4.4).
Pri peroralni uporabi vankomicina je pri bolnikih z vnetnimi črevesnimi boleznimi treba nadzirati koncentracijo vankomicina v serumu (glejte poglavje 4.4).
Each vial contains 1000 mg contains vancomycin hydrochloride equivalent to 1,000,000 IU vancomycin.
Ena viala vsebuje vankomicinijev klorid v količini, ki ustreza 1000 mg (1 000 000 i.e.) vankomicina.
In some countries, increasing cases of resistance are observed particularly in enterococci; multi-resistant strains of Enterococcus faecium are especially alarming.
Še posebej je zaskrbljujpče pojavljanje multiodpornih sevov bakterije Enterococcus faecium.
Vancomycin is indicated in all age groups for the treatment of Clostridium difficile infection (CDI) (see sections 4.2, 4.4 and 5.1).
Vankomicin uporabljamo za vse starostne skupine za zdravljenje okužb z bakterijo Clostridium difficile (glejte poglavja 4.2, 4.4 in 5.1).
Vancomycin diffuses readily across the placenta and is distributed into cord blood.
Vankomicin skozi placento prehaja v popkovnično kri.
Each vial contains 500 mg vancomycin hydrochloride equivalent to 500,000 IU vancomycin.
Ena viala vsebuje vankomicinijev klorid v količini, ki ustreza 500 mg (500 000 i.e.) vankomicina.
[For all vancomycin 125 mg capsule] <{(Invented) vancomycin 125mg capsule}>
[Za vse kapsule vankomicina 125 mg] <{(Ime zdravila) 125 mg kapsule}>
Anti-diarrhoeic medicinal products must not be given.
Bolniku ne smemo dati zdravil proti driski.
In patients with impaired renal function the terminal elimination half- life of vancomycin is prolonged and the total body clearance is reduced.
Pri bolnikih z ledvično okvaro je razpolovni čas izločanja podaljšan in skupni očistek manjši.
Continuous vancomycin infusion may be considered, e.g., in patients with unstable vancomycin clearance.
V nekaterih primerih, npr. pri bolnikih z nestabilnim očistkom vankomicina, lahko razmislimo o kontinuirani infuziji.
This may lead to vancomycin accumulation in patients with co-existing renal impairment.
To lahko pri bolnikih, ki imajo hkrati ledvično okvaro, privede do kopičenja vankomicina.
Serial tests of auditory function may be helpful in order to minimise the risk of ototoxicity in patients with an underlying hearing loss, or who are receiving concomitant therapy with an ototoxic agent such as an aminoglycoside.
Priporočljivo je redno preverjanje sluha, kar lahko pomaga zmanjšati tveganje za ototoksičnost pri bolnikih s prisotno izgubo sluha ali tistih, ki se hkrati zdravijo z ototoksičnimi snovmi, kot so denimo aminoglikozidi.
[For all vancomycin 250 mg capsule] <{(Invented) vancomycin 250mg capsule}>
[Za vse kapsule vankomicina 250 mg] <{(Ime zdravila) 250 mg kapsule}>
[For parenteral formulations authorised for perioperative antibacterial prophylaxis, include the wording as follows:]
[Za parenteralna zdravila, odobrena za perioperativno preprečevanje bakterijskih okužb, vnesite spodnje besedilo:]
[For parenteral formulations authorised for intraperitoneal use, the indication should be as follows:] Intraperitoneal administration
[Za parenteralna zdravila, odobrena za intraperitonealno uporabo, je indikacija naslednja:] Intraperitonealna uporaba
Vancomycin is indicated in all age groups for the treatment of peritoneal dialysis-associated peritonitis (see sections 4.2, 4.4 and 5.1).
Vankomicin uporabljamo za vse starostne skupine za zdravljenje peritonitisa, ki je posledica peritonealne dialize (glejte poglavja 4.2, 4.4 in 5.1).
Reversible neutropenia, agranulocytosis, eosinophilia, thrombocytopenia, pancytopenia.
Bolezni krvi in limfatičnega sistema: Redki reverzibilna nevtropenija, agranulocitoza, eozinofilija, trombocitopenija, pancitopenija
Adults and adolescents aged 12 to less than 18 years old
Odrasli in mladostniki (od 12 do 18 let)
Commonly susceptible species Gram positive
Vrste, ki so navadno občutljive Po Gramu pozitivne Enterococcus faecalis
If you get any side effects, talk to your doctor, hospital pharmacist or nurse.
Če ste negotovi, se posvetujte z zdravnikom ali farmacevtom.
Anti-motility agents should be avoided and proton pump inhibitor use should be reconsidered.
Treba se je izogibati snovem, ki zavirajo peristaltično gibanje črevesa, in treba je proučiti ustreznost uporabe zaviralcev protonske črpalke.
[For parenteral formulations authorised for oral use:] If given for treatment of gastric disorders (so called Pseudomembranous colitis), the medicinal product must be administrated as a solution for oral use (you will take the medicine by mouth).
Če je zdravilo namenjeno zdravljenju želodčnih bolezni (t. i. psevdomembranskega kolitisa), mora biti pripravljeno kot raztopina za peroralno uporabo (zdravilo boste zaužili).
[The below wording should be introduced in this section for all vancomycin containing products] Consideration should be given to official guidance on the appropriate use of antibacterial agents.
[Besedilo spodaj je treba vnesti v to poglavje za vsa zdravila, ki vsebujejo vankomicin.]
Respiratory, thoracic and mediastinal disorders: Common
Bolezni dihal, prsnega koša in mediastinalnega prostora: Pogosti dispneja, stridor
Powder for concentrate for solution for infusion
Prašek za koncentrat za raztopino za infundiranje 1.
Susceptible ≤ 2 mg/L
Občutljivi organizmi ≤ 2 mg/l
[for vancomycin powder for concentrate for infusion authorised for oral use] Vancomycin can be given orally in adults and children for the treament of infection of the mucosa of the small and the large intestines with damage to the mucosae (pseudomembranous colitis), caused by the Clostridium difficile bacterium.
Vankomicin lahko damo peroralno odraslim in otrokom za zdravljenje okužb sluznice tankega in debelega črevesa s poškodbami sluznice (psevdomembranski kolitis), ki so posledica bakterije Clostridium difficile.
Amendments to relevant sections of the summary of product characteristics and the package leaflets
PRILOGA III POVZETEK GLAVNIH ZNAČILNOSTI ZDRAVILA, OZNAČEVANJE IN NAVODILO ZA UPORABO
Talk to your doctor or hospital pharmacist or nurse during treatment with Vancomycin if: - You are receiving vancomycin for a long time (you may need to have your blood, hepatic and kidneys tested during treatment).
- prejemate vankomicin za zdravljenje driske zaradi okužbe z bakterijo Clostridium difficile v obliki infuzije namesto peroralno Med zdravljenjem z zdravilom Vankomicin se posvetujte s svojim zdravnikom, bolnišničnim farmacevtom ali medicinsko sestro, če: - prejemate vankomicin daljše obdobje (med zdravljenjem boste morali opravljati preiskave krvi ter delovanja jeter in ledvic) - se vam med zdravljenjem na koži pojavi kakršna koli reakcija - dobite hudo ali dolgotrajno drisko med jemanjem vankomicina.
[For all vancomycin 1000 mg powder for concentrate for solution for infusion] <{(Invented) vancomycin 1000mg powder for concentrate for solution for infusion}>
[Za vse praške vankomicin za koncentrat za raztopino za infundiranje 1000] <{(Izmišljeno ime) 1000 mg prašek za koncentrat za pripravo raztopine za infundiranje}>
[For all vancomycin 500 mg powder for concentrate for solution for infusion] <{(Invented) vancomycin 500mg powder for concentrate for solution for infusion}>
[Za vse praške vankomicin za koncentrat za raztopino za infundiranje 500 mg] <{(Izmišljeno ime) 500 mg prašek za koncentrat za raztopino za infundiranje}>
Acquired resistance to glycopeptides is most common in enterococci and is based on acquisition of various van gene complexes which modifies the D-alanyl-D-alanine target to D-alanyl-D-lactate or Dalanyl-D-serine which bind vancomycin poorly.
Pridobljena odpornost na glikopeptide je najpogostejša pri enterokokih in temelji na pridobitvi različnih genskih kompleksov van.