natgillin/translations-raw huggingface dataset:
• If you experience visual changes, bad or frequent headache, associated with feeling sick (nausea) or vomiting, especially at the start of treatment, tell your doctor immediately.
• Če opazite spremembe vida, imate hude ali pogoste glavobole, povezane s siljenjem na bruhanje (navzea) ali z bruhanjem, še posebej po uvedbi zdravljenja, o tem nemudoma obvestite svojega zdravnika.
As shown by the illustrations below, NutropinAq pen and cartridges are available in two designs (with or without additional yellow colour).
Injekcijski peresnik NutropinAq Pen in vložki so na voljo v dveh zunanjih podobah (z ali brez dodatne rumene barve), kot je prikazano spodaj.
During pregnancy, maternal somatropin will largely be replaced by placental growth hormone.
Med nosečnostjo placentni rastni hormon v glavnem nadomesti materin somatropin.
Rare: Gynaecomastia
Redki: ginekomastija
Now turn the black dose knob clockwise (See illustration) by one click (0.1mg).
Zdaj zasučite črni odmerni gumb v smeri urinega kazalca (glejte sliko) za en klik (0,1 mg).
Growth failure associated with chronic renal insufficiency
Zaostanek v rasti, povezan s kronično ledvično insuficienco
There is no antidote for somatropin overdose.
Antidota za primere prevelikega odmerjanja somatropina ni.
Serum calcium is not significantly altered by somatropin.
Kalcija v serumu somatropin ne spremeni bistveno.
Needles from other countries may not fit on your NutropinAq Pen.
Zgodi se lahko, da se igle iz drugih držav ne prilegajo vašemu injekcijskemu peresniku NutropinAq Pen.
Thus, the greatest improvement in adult height was observed in patients who received early GH treatment and oestrogen after age 14 years.
Tako je bilo največje izboljšanje telesne višine v odrasli dobi doseženo pri bolnicah, ki so se zgodaj začele zdraviti z rastnim hormonom, z estrogenom pa po 14. letu starosti.
Your doctor or nurse will recommend a needle that is appropriate for you.
Zdravnik ali medicinska sestra vam bosta svetovala za vas primerno iglo.
Monitoring is advisable when somatropin is administered in combination with medicinal products known to be metabolised by CYP450 liver enzymes, such as corticosteroids, sex steroids, anticonvulsants, and cyclosporin.
Med uporabo somatropina v kombinaciji z zdravili, za katera je znano, da se presnavljajo z jetrnimi encimi CYP450, kot na primer kortikosteroidi, spolni steroidi, antiepileptiki ali ciklosporin, je priporočljivo nadziranje.
In patients with severe liver dysfunction a reduction in somatropin clearance has been noted.
Pri bolnikih s hudo motenim delovanjem jeter so opazili zmanjšanje očistka somatropina.
Children with growth failure due to inadequate growth hormone secretion (n=236) Common: central nervous system neoplasm (2 patients experienced a recurrent medulloblastoma, 1 patient experienced a histiocytoma).
Otroci z zaostankom v rasti zaradi nezadostnega izločanja rastnega hormona (n=236) Pogosti: novotvorbe centralnega živčnega sistema (dva bolnika s ponovitvijo meduloblastoma, en bolnik s histiocitomom).
Growth failure associated with Turner syndrome
Zaostanek v rasti, povezan s Turnerjevim sindromom
Information about the pharmacokinetics of somatropin in elderly and paediatric populations, in different races or genders and in patients with renal or hepatic impairment is incomplete.
Podatki o farmakokinetiki somatropina pri starostnikih, pediatrični populaciji, različnih rasah ali spolih in bolnikih z okvaro ledvic ali jeter, so nepopolni.
Approximately 2.5 % of patients from the NCGS have experienced drug related adverse reactions.
V študiji NCGS so se neželeni učinki zdravila pojavili pri približno 2,5 % bolnikov.
The volume of distribution at steady state for somatropin in healthy adult males is about 50 ml/kg bodyweight, approximating the serum volume.
Volumen porazdelitve somatropina v stanju dinamičnega ravnovesja je pri zdravih odraslih moških okrog 50 ml/kg telesne mase in se približuje volumnu seruma.
After intravenous bolus administration of somatropin, the mean terminal half-life t½ or t½is about 20 minutes and the mean clearance is reported to be in the range of 116 - 174 ml/h/kg.
Po intravenski bolusni aplikaciji somatropina je povprečni končni razpolovni čas t½ oz. t½ približno 20 minut, povprečni očistek pa od 116 - 174 ml/uro/kg.
Decrease in the number of red blood cells in the blood (anaemia), decrease in blood sugar level (hypoglycaemia) and increase in phosphate levels (hyperphosphatemia).
Zmanjšanje števila rdečih krvnih celic (anemija), znižanje vrednosti krvnega sladkorja (hipoglikemija) in zvišanje vrednosti fosfatov (hiperfosfatemija).
Do not take a double dose to make up for a missed dose.
Ne uporabite dvojnega odmerka, če ste pozabili uporabiti prejšnji odmerek.
Patients with ACTH deficiency should have their glucocorticoid replacement therapy carefully adjusted to avoid any inhibitory effect on growth.
Pri bolnikih s pomanjkanjem ACTH je treba nadomestno zdravljenje z glukokortikoidi skrbno prilagoditi, da bi preprečili zaviralni učinek na rast.
België/Belgique/Belgien Luxembourg/Luxemburg Ipsen NV Guldensporenpark 87 B-9820 Merelbeke België /Belgique/Belgien Tél/Tel: + 32 - 9 - 243 96 00
België/Belgique/Belgien Luxembourg/Luxemburg Ipsen NV Guldensporenpark 87 B-9820 Merelbeke België /Belgique/Belgien
What you need to know before you use NutropinAq
Kaj morate vedeti, preden boste uporabili zdravilo NutropinAq
It is then cleaved within renal cells into its constituent amino acids, which return to the systemic circulation.
V ledvičnih celicah se nato razcepi v aminokisline, ki ga gradijo, te pa se vrnejo v sistemski obtok.
In both studies there was a significant improvement in growth rate in the naïve patients, increasing from 4.2 to 10.9 cm/year in one study and from 4.8 to 11.2 cm/year in the other at 12 months.
V obeh študijah je bilo pri predhodno nezdravljenih bolnikih doseženo pomembno izboljšanje stopnje rasti, in sicer se je po 12 mesecih v eni študiji stopnja rasti povečala iz 4,2 na 10,9 cm/leto, v drugi pa iz 4,8 na 11,2 cm/leto.
Enlarged tonsils leading to snoring, difficulty breathing or swallowing, brief interruption of breathing during sleep (sleep apnea), or fluid in the ear, as well as infections of the ear.
Zvečanje tonzil, kar lahko povzroči smrčanje, težave pri dihanju ali požiranju ali kratko prekinitev dihanja med spanjem (apneja v spanju), kopičenje tekočine v ušesu in okužbe ušesa.
Treatment must be discontinued if there is evidence of tumour growth.
Zdravljenje je treba prekiniti, če obstajajo dokazi o rasti tumorja.
Predicted adult height (PAH) increased from 157.7-161.0 cm at baseline to 161.4-167.4 cm at Month 12 and 166.2-171.1 cm at Month 36.
Pričakovana telesna višina v odrasli dobi (PAH- predicted adult height) se je iz 157,7-161,0 cm v izhodišču povečala na 161,4-167,4 cm v 12. mesecu in 166,2-171,1 cm v 36. mesecu.
Both the liver and the kidney have been shown to be important protein catabolising organs for growth hormone.
Dokazano je, da so jetra in ledvice pomembni organi za beljakovinski katabolizem rastnega hormona.
Q: Why do I have to rewind the black dose knob on my NutropinAq Pen every time I replace the cartridge?
V: Zakaj moram črni odmerni gumb na injekcijskem peresniku NutropinAq Pen prevrteti nazaj vsakič, ko zamenjam vložek?
Rare: Abnormal behaviour, depression, insomnia
Redki: nenormalno vedenje, depresija, nespečnost
This is reflected by nitrogen retention as demonstrated by a decline in urinary nitrogen excretion and blood urea nitrogen during growth hormone therapy.
To se kaže z retenco dušika, ki se kaže kot zmanjšano izločanje dušika v urin in znižanjem sečnine v krvi med zdravljenjem z rastnim hormonom.
Table 1 contains very common (≥ 1/10), common (≥ 1/100, < 1/10); uncommon (≥ 1/1000, < 1/100); rare (≥ 1/10,000, < 1/1,000) adverse reactions which occurred in clinical trials and a post-marketing surveillance survey.
Pogostnost neželenih učinkov je navedena v skladu z naslednjim dogovorom: zelo pogosti (≥ 1/10), pogosti (≥ 1/100, < 1/10), občasni (≥ 1/1.000, < 1/100) in redki (≥ 1/10.000, < 1/1.000).
A: If you drop the NutropinAq Pen, check to see if the cartridge is damaged.
O: Če vam injekcijski peresnik NutropinAq Pen pade, preverite, če je vložek poškodovan.
Neoplasms (malignant and benign) were reported in both the pivotal and supportive clinical trials and in the post-marketing surveillance survey (see sections 4.3 and 4.4).
O novotvorbah (malignih in benignih) so poročali tako v ključnih kot podpornih kliničnih preskušanjih in tudi med spremljanjem zdravila v obdobju trženja (glejte poglavji 4.3 in 4.4).
Very common (may affect more than 1 in 10 patients)
Zelo pogosti (pojavijo se lahko pri več kot 1 od 10 bolnikov)
The NutropinAq dosage and administration schedule should be individualised for each patient.
Odmerjanje in urnik uporabe zdravila NutropinAq je treba določiti za vsakega bolnika posamezno.
We also suggest you consult your doctor or nurse for a demonstration.
Svetujemo tudi, da vam zdravnik ali medicinska sestra prikažeta njegovo uporabo.
If you use more NutropinAq than you should
Če ste uporabili večji odmerek zdravila NutropinAq, kot bi smeli
Two pivotal, open label, uncontrolled, multicentre studies have been conducted, one exclusively in previously untreated patients (n=67), and the other in previously untreated patients (n=63)
Izvedeni sta bili dve ključni, odprti, nenadzorovani multicentrični študiji, ena izključno pri predhodno nezdravljenih bolnikih (n=67), druga pa pri predhodno nezdravljenih bolnikih (n=63) in pri otrocih, ki so se predhodno zdravili s somatropinom (n=9).
Patients with inadequate growth hormone secretion sometimes experience fasting hypoglycaemia that is improved by treatment with somatropin.
Bolniki z nezadostnim izločanjem rastnega hormona včasih doživljajo hipoglikemijo na tešče, ki se z zdravljenjem s somatropinom izboljša.
Intracranial hypertension was reported in the post-marketing surveillance survey.
O pojavu intrakranialne hipertenzije so poročali med spremljanjem zdravila v obdobju trženja.
Do not use NutropinAq:
Ne uporabljajte zdravila NutropinAq:
Pain, bleeding, bruising, rash and itching at the site of injection.
Bolečina, krvavitev, modrice, izpuščaj in srbenje na mestu injiciranja.
Somatropin therapy should be continued in children and adolescents until their epiphysis are closed, or up to the time of renal transplantation.
Zdravljenje s somatropinom pri otrocih in mladostnikih naj se nadaljuje do zapiranja epifiz ali do časa presaditve ledvic.
Difficulty to hold-in urine (urinary incontinence), high frequency (pollakiuria) and volume (polyuria) of urination.
Nezmožnost zadrževanja urina (urinska inkontinenca), pogosto uriniranje (polakisurija) in izločanje velike količine urina (poliurija).
Do not change the dosage without consulting your doctor.
Odmerka brez posveta z zdravnikom ne smete spreminjati.
Supporting data from a study on adult-onset GHD patients were generally consistent with those of the pivotal studies, with some improvements in BMD.
Podporni podatki iz študije pri bolnikih s pomanjkanjem rastnega hormona z začetkom v odrasli dobi se na splošno ujemajo s podatki iz ključnih študij, z nekaterimi izboljšavami vrednosti BMD.
Somatropin is known to be associated with inhibition of the reproduction in male and female rats at doses of 3 IU/kg/day (1 mg/kg/day) or more, with reduced copulation and conception rates, lengthened or absent oestrous cycles, and at 10 IU/kg/day (3.3 mg/kg/day).
Znano je, da somatropin pri odmerkih 3 i.e./kg/dan (1 mg/kg/dan) ali večjih zavira procese razmnoževanja pri samcih in samicah podgan, pri čemer se zmanjša delež parjenj in koncepcij, estrusni cikel pa se pri odmerku 10 i.e./kg/dan (3,3 mg/kg/dan) podaljša ali izostane.
However, no cause and effect relationship with growth hormone treatment has been proven.
Vendar pa ni dokazov o vzročno-posledični povezavi z zdravljenjem z rastnim hormonom.
• Do not let your NutropinAq Pen and/or cartridge freeze.
• Injekcijskega peresnika NutropinAq Pen in/ali vložka ne smete pustiti, da zamrzneta.
This is not unusual for solutions containing proteins like NutropinAq and does not affect the strength of the product.
Za raztopine, kakršna je NutropinAq, ki vsebujejo beljakovine, to ni nič nenavadnega in ne pomeni, da je moč zdravila oslabela.
The dose should be adjusted stepwise, controlled by serum Insulin-like Growth Factor-1 (IGF-I) values.
Odmerek je treba prilagajati postopoma in glede na vrednosti insulinu podobnega rastnega dejavnika I (IGF-I) v serumu.
The effects of growth hormone on recovery were studied in two placebo-controlled clinical trials involving 522 adult patients who were critically ill due to complications following open-heart or abdominal surgery, multiple accidental traumas, or who were having acute respiratory failure.
Učinke rastnega hormona na okrevanje so proučevali v dveh s placebom kontroliranih kliničnih preskušanjih, ki sta zajeli 522 odraslih bolnikov, kritično bolnih zaradi zapletov po operaciji na odprtem srcu ali abdomnu, po politravmi ali akutni respiratorni odpovedi.
Glucocorticoids use
Uporaba glukokortikoidov
• If you have a replacement therapy with glucocorticoids you should consult your doctor regularly as you may need adjustment of your glucocorticoid dose.
• Če se zdravite z nadomeščanjem glukokortikoidov, se morate redno posvetovati s svojim zdravnikom, saj bo odmerek glukokortikoida morda treba prilagoditi.
In all reported cases, intracranial hypertension associated signs and symptoms resolved after reduction of the NutropinAq dose or termination of therapy (see section 4.4).
V vseh opisanih primerih so znaki in simptomi, povezani z intrakranialno hipertenzijo, izzveneli po zmanjšanju odmerka zdravila NutropinAq ali prekinitvi zdravljenja (glejte poglavje 4.4).
Somatropin stimulates growth rate and increases adult height in children who lack endogenous growth hormone and in children who have growth failure due to Turner Syndrome or CRI.
Somatropin stimulira hitrost rasti in zveča odraslo višino pri otrocih, ki jim primanjkuje endogenega rastnega hormona, in pri otrocih z motnjo rasti zaradi Turnerjevega sindroma ali kronične insuficience ledvic.
Allow the cartridge to come to room temperature and gently swirl.
Pustite, da se vložek segreje na sobno temperaturo in previdno vrtite.
In children it tells the body to grow, help the bones to develop normally and, in later adult life, GH helps to maintain a normal body shape and metabolism.
Pri otrocih uravnava rast telesa in pomaga k normalnemu razvoju kosti, kasneje, v odrasli dobi, pa rastni hormon pomaga ohranjati normalno obliko telesa in presnovo.
• When you have Turner syndrome.
• če ima deklica Turnerjev sindrom.
The NutropinAq Pen allows for administration of a minimum dose of 0.1 mg to a maximum dose of 4.0 mg, in 0.1 mg increments.
Injekcijski peresnik NutropinAq Pen omogoča aplikacijo odmerkov od najmanjšega 0,1 mg do največjega 4,0 mg v stopnjah po 0,1 mg.
Somatropin therapy should be continued in children and adolescents until their epiphysis are closed.
Zdravljenje s somatropinom pri otrocih in mladostnikih naj se nadaljuje do zapiranja epifiz.
Gender No gender-specific pharmacokinetic studies have been done with NutropinAq.
Za spol specifične farmakokinetične študije z zdravilom NutropinAq niso bile izvedene.
Conversely, if a woman on NutropinAq discontinues oral oestrogen therapy, the dose of NutropinAq may need to be reduced to avoid excess of growth hormone and/or side effects (see section 4.5).
Nasprotno, če ženska, ki se zdravi z zdravilom NutropinAq, preneha z zdravljenjem s peroralnimi estrogeni, bo odmerek zdravila NutropinAq morda treba zmanjšati, da se prepreči presežek rastnega hormona in/ali pojav neželenih učinkov (glejte poglavje 4.5).
Do not use NutropinAq if you notice that the solution is cloudy.
Ne uporabljajte zdravila NutropinAq, če opazite, da je raztopina motna.
One ml contains 5 mg of somatropin*
En ml vsebuje 5 mg somatropina.
The available literature indicates that the pharmacokinetics of somatropin are similar in men and women.
Razpoložljiva literatura kaže, da je farmakokinetika somatropina pri moških in ženskah podobna.
What NutropinAq looks like and contents of the pack
Izgled zdravila NutropinAq in vsebina pakiranja
No conventional reproduction studies were performed.
Običajne študije vpliva na sposobnost razmnoževanje niso bile izvedene.
In all reported cases, intracranial hypertension-associated signs and symptoms resolved after reduction of the somatropin dose or termination of the therapy.
V vseh opisanih primerih so znaki in simptomi, povezani z intrakranialno hipertenzijo, izginili po zmanjšanju odmerka somatropina ali prekinitvi zdravljenja.
Children with growth failure associated with chronic renal insufficiency (n=171) Common: renal failure, peritonitis, osteonecrosis, blood creatinine increase.
Otroci z zaostankom v rasti, povezanim s kronično insuficienco ledvic (n=171) Pogosti: odpoved ledvic, peritonitis, osteonekroza, zvišanje kreatinina v krvi.
* Somatropin is a human growth hormone produced in Escherichia coli cells by recombinant DNA technology.
* Somatropin je humani rastni hormon, pridobljen iz celic Escherichie coli z genskim inženirstvom.
• if you have complications after a major surgery (open-heart or abdominal surgery), a multiple trauma, acute respiratory failure, or similar conditions.
• če imate zaplete po veliki operaciji (operacija na odprtem srcu ali v trebušni votlini), politravmo, akutno respiratorno odpoved ali podobna stanja.
If you are using the active shield, slide the shield onto the pen and push the 2 black lock knobs on the needle shield toward the tip.
Če uporabljate aktivni ščitnik, ga namestite na injekcijski peresnik in potisnite 2 črna zaskočna gumba na ščitniku igle proti konici.
2 ml of solution in a cartridge (Type I glass) closed with a stopper (butyl rubber) and a seal (rubber).
2 ml raztopine v vložku iz stekla tipa I, zaprtim z zamaškom iz butilne gume in gumijasto zaporo.
The dosage scale located beside the window of the cartridge holder should not be used as a dose measurement.
Odmerne skale ob okencu držala vložka ne smete uporabljati za merjenje odmerka.
Since somatropin therapy following renal transplantation has not been adequately tested, NutropinAq treatment should be terminated after that surgery.
Zdravljenje s somatropinom po presaditvi ledvice ni dovolj preiskušeno, zato je treba zdravljenje z zdravilom NutropinAq po takšni operaciji ukiniti.
Q: How long can I keep my NutropinAq Pen and cartridge outside the refrigerator?
V: Koliko časa imam lahko injekcijski peresnik NutropinAq Pen in vložek zunaj hladilnika?
Growth Hormone (GH) is a chemical messenger made by a small gland in your brain called the pituitary.
Rastni hormon je kemični prenašalec, ki nastaja v majhni žlezi v možganih, imenovani hipofiza.
In adults with growth hormone deficiency:
Odrasli s pomanjkanjem rastnega hormona:
Carefully remove both protective caps from the needle by pulling gently.
S previdnim potegom z igle pazljivo odstranite oba zaščitna pokrovčka.
In genotoxicity studies with other recombinant growth hormone preparations, there was no evidence of gene mutation in bacterial reverse mutation assays, chromosomal damage in human lymphocyte and mouse bone marrow cells, gene conversion in yeast or unscheduled DNA synthesis in human carcinoma cells.
Pri študijah genotoksičnosti drugih rekombinantnih pripravkov rastnega hormona niso zasledili genskih mutacij pri bakterijskem testu reverznih mutacij, kromosomskih poškodb na humanih limfocitih in mišjih celicah kostnega mozga, genskih zamenjav pri kvasovkah ali nepredvidene sinteze DNA na humanih rakavih celicah.
This medicinal product contains less than 1 mmol sodium (23 mg) per vial, i.e. essentially “sodiumfree”.
To zdravilo vsebuje manj kot 1 mmol (23 mg) natrija na vložek, kar v bistvu pomeni “brez natrija”.
• Clean the cartridge rubber seal with an alcohol swab or cotton ball saturated with alcohol.
• Očistite gumijasto zaporo vložka s kosmom vate, prepojenim z alkoholom, ali z alkoholnim zložencem.
Somatropin induces retention of sodium, potassium and phosphorus.
Somatropin sproži zadrževanje natrija, kalija in fosforja.
This side effect is uncommon, it may affect up to 1 in 100 patients.
Ta neželeni učinek je občasen, pojavi se lahko pri do 1 od 100 bolnikov.
• If you have complications after major surgery (open-heart or abdominal surgery), multiple trauma, acute respiratory failure, or similar conditions, your doctor should decide whether it is safe to continue NutropinAq treatment.
• Če imate zaplete po veliki operaciji (operacija na odprtem srcu ali v trebušni votlini), politravmo, akutno respiratorno odpoved ali podobna stanja, mora zdravnik presoditi, če je nadaljevanje zdravljenja z zdravilom NutropinAq varno.
Swelling of the hands and feet due to an accumulation of fluid (peripheral oedema) sometimes associated with localised muscle pain (myalgia) and pain in joints (arthralgia).
Otekanje rok in nog zaradi kopičenja tekočine (periferni edem), ki je včasih povezano z lokalizirano bolečino v mišicah (mialgija) in bolečino v sklepih (artralgija).
If you have scoliosis, you will need to be frequently checked for an increase in the curve.
Če imate skoliozo, boste morali pogosto na preglede zaradi morebitnega napredovanja ukrivljenosti.
Bone disorder where the upper leg (femur) moves apart from the hip (slipped capital femoral epiphysis).
Bolezen kosti, kjer se stegnenica (femur) premakne stran od kolčnega sklepa (zdrs epifize glavice stegnenice).
There was also a significant increase in height SDS in somatropin-treated patients, from -2.9 to -2.7 at baseline to -1.6 to -1.4 at 24 months.
Pomembno se je povečala tudi vrednost SDS telesne višine pri bolnikih, ki so se zdravili somatropinom, in sicer od vrednosti -2,9 do -2,7 v izhodišču do vrednosti od -1,6 do -1,4 v 24. mesecu.
These could be signs of a temporary increase in pressure within the brain (intracranial hypertension).
To so lahko znaki prehodnega povečanja tlaka v možganih (intrakranialna hipertenzija).
If a woman taking NutropinAq begins oral oestrogen therapy, the dose of NutropinAq may need to be increased to maintain the serum IGF-1 levels within the normal age appropriate range.
Uporaba skupaj s peroralnim estrogenskim zdravljenjem Če se ženska, ki jemlje zdravilo NutropinAq, začne zdraviti s peroralnimi estrogeni, bo odmerek zdravila NutropinAq morda treba povečati, da se vrednosti serumskega IGF-1 ohranijo v normalnem starostno primernem razponu.
The use of NutropinAq in patients with chronic renal insufficiency receiving glucocorticoid therapy has not been evaluated.
Uporaba zdravila NutropinAq pri bolnikih s kronično odpovedjo ledvic, ki dobivajo glukokortikoide, ni raziskana.
The active substance of NutropinAq is somatropin*.
- Učinkovina zdravila NutropinAq je somatropin*.
In patients treated with somatropin, previously undiagnosed central (secondary) hypoadrenalism may be unmasked requiring glucocorticoid replacement therapy.
Pri bolnikih, ki se zdravijo s somatropinom, se lahko izrazi predhodno prikriti centralni (sekundarni) hipoadrenalizem, ki zahteva nadomestno zdravljenje z glukokortikoidi.
• If during growing, a limp or hip or knee pain develops, ask the doctor for advice.
• Če se med rastjo pojavi šepanje ali bolečina v kolku ali kolenu, se posvetujte z zdravnikom.
The working of the pen and the content of the cartridges are the same for both designs.
Delovanje injekcijskega peresnika in vložkov je enako pri obeh zunanjih podobah.
Serum concentration of inorganic phosphorus are increased in patients with growth hormone deficiency after NutropinAq therapy due to metabolic activity associated with bone growth and increased tubular reabsorption in the kidney.
Koncentracija neorganskega fosforja v serumu se pri bolnikih s pomanjkanjem rastnega hormona po zdravljenju z zdravilom NutropinAq zveča zaradi presnovnega delovanja, povezanega z rastjo kosti in večjo reabsorpcijo v ledvičnih tubulih.
Persistent stinging, burning sensation, pain and/or numbness in the palm of the hand due to a trapped nerve at the wrist (carpal tunnel syndrome).
Stalno zbadanje, pekoč občutek, bolečina in/ali odrevenelost v dlani zaradi ujetega živca v zapestju (sindrom karpalnega kanala).