natgillin/translations-raw huggingface dataset:
The CHMP decided that Mycamine's benefits are greater than its risks for the treatment of invasive candidiasis and of oesophageal candidiasis, and for the prophylaxis of Candida infection in patients undergoing allogeneic haematopoietic stem cell transplantation or who are expected to have neutropenia for 10 or more days.
CHMP je zaključil, da so koristi zdravila Mycamine večje od z njim povezanih tveganj za zdravljenje invazivne kandidoze in kandidoze požiralnika ter za preprečevanje okužbe s Candido pri bolnikih po alogenski presaditvi hematopoetskih matičnih celic ali pri bolnikih, za katere predvidevajo, da bodo imeli 10- ali večdnevno nevtropenijo.
Because of a possible risk of liver tumours, Mycamine is only to be used if other antifungal medicines are not appropriate.
Zaradi morebitne nevarnosti razvoja jetrnih tumorjev naj bi se zdravilo Mycamine uporabljalo le, če druga protiglivična zdravila niso primerna.
The list of fungi against which Mycamine is active can be found in the summary of product characteristics (also part of the EPAR).
Za seznam glivic, proti katerim deluje zdravilo Mycamine, glejte povzetek glavnih značilnosti zdravila (ki je tudi del EPAR).
For the treatment of invasive candidiasis, Mycamine was compared with amphotericin B in a study involving 531 adults and 106 children, including newborns and premature babies.
Pri zdravljenju invazivne kandidoze so zdravilo Mycamine primerjali z amfotericinom B v študiji, v katero je bilo vključenih 531 odraslih in 106 otrok, vključno z novorojenčki in nedonošenčki.
Additional common side effects in children (seen in between 1 and 10 children in 100) are thrombocytopenia (low blood platelet counts), tachycardia (rapid heart rate), hypertension (high blood pressure), hypotension (low blood pressure), hepatomegaly (enlarged liver), acute renal failure (sudden kidney failure) and increased blood urea levels.
Dodatni pogosti neželeni učinki pri otrocih (opaženi pri 1 do 10 otrocih od 100 otrok) so trombocitopenija (nizka raven krvnih ploščic), tahikardija (hitro utripanje srca), hipertenzija (visok krvni tlak), hipotenzija (nizek krvni tlak), hepatomegalija (povečana jetra), akutna ledvična odpoved in povečane ravni sečnine v krvi.
The active substance in Mycamine, micafungin, is an antifungal medicine, which belongs to the group ‘echinocandins'.
Zdravilna učinkovina zdravila Mycamine, mikafungin, je protiglivično zdravilo, ki spada v skupino ehinokandinov.
• to prevent infection with Candida in patients who are having a bone marrow transplant or who are expected to have neutropenia (low levels of neutrophils, a type of white blood cell) for 10 days or more.
• za preprečevanje okužbe z glivo Candida pri bolnikih pred presaditvijo kostnega mozga ali pri bolnikih, za katere predvidevajo, da bodo 10 ali več dni imeli nevtropenijo (nizko raven nevtrofilcev, vrste belih krvničk).
Why has Mycamine been approved?
Zakaj je bilo zdravilo Mycamine odobreno?
However due to a possible risk of liver tumour, based on results seen in rats, the Committee recommended that Mycamine should only be used if other antifungal medicines are not appropriate.
Vendar je Odbor zaradi morebitne nevarnosti jetrnega tumorja glede na izide študij s podganami priporočil uporabo zdravila Mycamine le, če ni drugih primernih protiglivičnih zdravil.
The full EPAR for Mycamine can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports.
Celotno evropsko javno poročilo o oceni zdravila (EPAR) za zdravilo Mycamine je na voljo na spletni strani agencije: ema.europa.eu/Find medicine/Human medicines/European Public Assessment Reports Za več informacij o zdravljenju z zdravilom Mycamine preberite navodilo za uporabo (ki je prav tako del EPAR) ali se posvetujte z zdravnikom ali farmacevtom.
When Mycamine is used to prevent Candida infection, treatment should continue for one week after white blood cell counts have recovered.
Ko se zdravilo Mycamine uporablja za preprečevanje okužbe s Candido, mora zdravljenje trajati še en teden po vzpostavitvi normalnih vrednosti belih krvničk.
For the full list of all side effects reported with Mycamine, see the package leaflet.
Za celoten seznam neželenih učinkov, o katerih so poročali pri uporabi zdravila Mycamine, glejte navodilo za uporabo.
For the treatment of oesophageal candidiasis, Mycamine was compared with fluconazole in a study involving 518 adults, and with caspofungin in another study involving 452 adults.
Pri zdravljenju kandidoze požiralnika so zdravilo Mycamine primerjali s flukonazolom v študiji, v katero je bilo vključenih 518 odraslih, ter s kaspofunginom v drugi študiji, v katero je bilo vključenih 452 odraslih.
Mycamine should not be used in people who may be hypersensitive (allergic) to micafungin, other echinocandins, or any of the other ingredients.
Zdravila Mycamine ne smejo uporabljati osebe, ki utegnejo biti preobčutljive za (alergične na) mikafungin ali katero koli drugo sestavino zdravila.
Mycamine is also used to treat candidiasis in the oesophagus (gullet) in patients over 16 years of age for whom intravenous treatment is suitable.
Zdravilo Mycamine se prav tako uporablja pri zdravljenju kandidoze požiralnika pri bolnikih, starejših od 16 let, za katere je intravensko zdravljenje primerno.
Patients being treated for invasive candidiasis should receive Mycamine for at least two weeks, and for a week after symptoms have resolved and there are no signs of fungus in the blood.
Bolniki, ki se zdravijo zaradi invazivne kandidoze, morajo zdravilo Mycamine prejemati najmanj dva tedna ter en teden po tem, ko simptomi izginejo in v krvi ni več znakov glivic.
Mycamine is a powder that is dissolved to make a solution for infusion (drip into a vein).
Zdravilo Mycamine je prašek za pripravo raztopine za infundiranje (kapalne infuzije v veno).
Because liver damage and tumours have been seen in rats receiving Mycamine for long periods, patients should be monitored for liver problems during Mycamine treatment using blood tests.
Ker so pri podganah, ki so daljše obdobje prejemale zdravilo Mycamine, opazili poškodbe jeter in tumorje, je treba med zdravljenjem z zdravilom Mycamine bolnike spremljati s krvnimi testi zaradi morebitnih težav z jetri.
Treatment should be stopped if there are persistent increases in liver enzymes.
V primeru trajnega povišanja jetrnih encimov je treba zdravljenje ustaviti.
For the prevention of candidiasis, Mycamine was compared with fluconazole in 889 adults and children undergoing a bone marrow transplant.
Pri preprečevanju kandidoze so zdravilo Mycamine primerjali s flukonazolom pri 889 odraslih in otrocih po presaditvi kostnega mozga.
Mycamine was as effective as the comparator medicines in the treatment of candidiasis.
Zdravilo Mycamine se je pri zdravljenju kandidoze izkazalo za enako učinkovito kot primerjalna zdravila.
Patients being treated for oesophageal candidiasis should continue to receive Mycamine for at least one week after symptoms have resolved.
Bolniki, ki se zdravijo zaradi kandidoze požiralnika, morajo zdravilo Mycamine prejemati še najmanj teden dni po prenehanju simptomov.
In the study of invasive candidiasis, around 90% of the adults receiving either Mycamine or amphotericin B were successfully treated.
V študiji invazivne kandidoze je bilo uspešno zdravljenih 90 % odraslih, ki so prejemali bodisi zdravilo Mycamine bodisi amfotericin B. Podobni rezultati so bili ugotovljeni pri otrocih.
Mycamine was more effective than fluconazole in preventing fungal infection in patients undergoing a bone marrow transplant: 80% of the patients (340 out of 425) receiving Mycamine did not develop a fungal infection, compared with 74% of the patients (336 out of 457) receiving fluconazole.
Zdravilo Mycamine je bilo učinkovitejše od flukonazola pri preprečevanju glivične okužbe pri bolnikih, ki so prestali presaditev kostnega mozga: pri 80 % bolnikov (340 od 425), ki so prejemali zdravilo
How has Mycamine been studied?
Kako je bilo zdravilo Mycamine raziskano?
What is Mycamine used for?
Za kaj se uporablja zdravilo Mycamine?
How does Mycamine work?
Kako zdravilo Mycamine deluje?
How is Mycamine used?
Kako se zdravilo Mycamine uporablja?
• to treat invasive candidiasis (a type of fungal infection caused by a yeast-like fungus called
• za zdravljenje invazivne kandidoze (vrste glivične okužbe, ki jo povzroča kvasovkam podobna gliva, imenovana Candida); „invazivna“ pomeni, da se je gliva razširila v tkivo in krvne žile;
What is Mycamine?
Kaj je zdravilo Mycamine?
EU/1/18/1310/001
EU/1/18/1310/001 Deferipron Lipomed
Blister (aluminium/PVC/PVDC)
500 mg filmsko obložena tableta peroralna uporaba pretisni omot (alu/PVC/PVDC)
Oral use
Jakost
2 tubes 12 tubes 20 tubes 40 tubes
2 tubi 12 tub 20 tub 40 tub
Repeat the administration after 7 days.
Dajanje ponovite po 7 dneh.
EU/2/14/170/0001 (2 tubes) EU/2/14/170/0002 (12 tubes) EU/2/14/170/0003 (20 tubes) EU/2/14/170/0004 (40 tubes)
EU/2/14/170/0001 (2 tubi) EU/2/14/170/0002 (12 tub) EU/2/14/170/0003 (20 tub) EU/2/14/170/0004 (40 tub)
Instructions for proper use:
Navodila za pravilno uporabo:
DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 31/07/2014
DATUM PRIDOBITVE/PODALJŠANJA DOVOLJENJA ZA PROMET Datum pridobitve dovoljenja za promet: 31/07/2014
1 mg For the full list of excipients, see section 6.1.
1 mg Za celoten seznam pomožnih snovi glejte poglavje 6.1.
ATC-vet code: QS02CA90.
Oznaka ATC vet: QS02CA90
These findings were not associated with clinical signs.
Ta opažanja niso bila povezana s kliničnimi znaki.
Do not use in dogs with generalised demodicosis.
Ne uporabite pri psih z generalizirano demodikozo.
To avoid this risk for the owners, it is recommended that this veterinary product is administered only by veterinarians or under their close supervision.
Da bi se lastniki izognili temu tveganju, se priporoča, da se to zdravilo za uporabo v veterinarski medicini daje samo s strani veterinarja ali pod njegovim strogim nadzorom.
Open the tube by twisting the soft tip.
Tubo odprite tako, da zavrtite mehko konico.
Detailed information on this veterinary medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu/ .
Podrobne informacije o tem zdravilu so na voljo na spletni strani Evropske agencije za zdravila (European Medicines Agency) (http://www.ema.europa.eu/).
Avoid accidental contact to the dog's eyes.
Izognite se nenamernemu stiku zdravila z očmi psa.
Cardboard box containing 2, 12, 20 or 40 tubes (each tube containing 2.05 g of product of which a single dose of 1.2 g can be extracted).
Kartonska škatla, ki vsebuje 2, 12, 20 ali 40 tub (vsaka tuba vsebuje 2,05 g zdravila, iz katerega se iztisne enkratni odmerek 1,2 g).
The maximum clinical response may not be seen until 21 days after the second administration.
Do največjega kliničnega odziva lahko pride šele po 21 dneh po drugem dajanju.
Terbinafine:
terbinafin:
In case of parasitic otitis, an appropriate acaricidal treatment should be implemented.
V primeru parazitskega vnetja sluhovoda je treba uvesti ustrezno akaricidno zdravljenje.
Do not use this veterinary medicinal product after the expiry date which is stated on the label after EXP.
Tega zdravila ne smete uporabljati po datumu izteka roka uporabnosti, navedenega na ovojnini za oznako »EXP«.
Additional corticosteroid treatments should be avoided.
Izogibajte se dodatnemu zdravljenju s kortikosteroidi.
If clinical signs develop, seek veterinary advice.
Če se razvijejo klinični znaki, se posvetujte z veterinarjem.
QUALITATIVE AND QUANTITATIVE COMPOSITION 1 dose (1.2 g) contains:
En odmerek (1,2 g) vsebuje:
If hypersensitivity to any of the components occurs, the ear should be thoroughly washed.
Če se pojavi preobčutljivost na katerokoli sestavino, morate uho temeljito sprati.
These findings are considered reversible.
Ta opažanja so bila reverzibilna.
Absorption occurred primarily during the first two to four days after administration, with low plasma concentrations (1 to 42 ng/ml) of active substances.
Do absorpcije je v glavnem prišlo v prvih dveh do štirih dneh po vnosu, plazemske koncentracije učinkovin pa so bile majhne (1 do 42 ng/ml).
Florfenicol is a bacteriostatic antibiotic which acts by inhibiting protein synthesis.
Florfenikol je bakteriostatski antibiotik, ki zavira sintezo beljakovin.
The finding was not correlated with pathological or clinical signs and was reversible.
Ta pojav ni bil povezan s patološkimi ali kliničnimi znaki in je bil reverzibilen.
Terbinafine is an allylamine with a pronounced fungicidal activity.
Terbinafin je alilamin z izrazito fungicidno aktivnostjo.
Whenever possible the use of the veterinary medicinal product should be based on identification of infecting organisms and susceptibility testing.
Če je le mogoče, zdravilo za uporabo v veterinarski medicini uporabljajte na osnovi identifikacije povzročitelja okužbe in testiranja občutljivosti.
The extent of percutaneous absorption of topical medications is determined by many factors including the integrity of the epidermal barrier.
Obseg perkutane absorpcije topikalnih zdravil določajo številni dejavniki, med njimi integriteta epidermalne pregrade.
CONTENTS BY WEIGHT, BY VOLUME OR BY NUMBER OF DOSES 1 dose
VSEBINA, IZRAŽENA Z MASO, PROSTORNINO ALI ŠTEVILOM ODMERKOV 1 odmerek
Terbinafine has a different mode of action than azole antifungals, therefore there is no cross resistance with azole antifungals.
Terbinafin ima drugačen način delovanja kot azolni antimikotiki, zato ni navzkrižne odpornosti z drugimi azolnimi antimikotiki.
Use with precaution in dogs with suspected or confirmed endocrine disorder (i.e. diabetes mellitus; hypo- or hyper-thyroid disease, etc.).
Uporabljajte previdno pri psih s potrjeno endokrino motnjo (tj. sladkorno boleznijo, hipo- ali hipertiroidizmom itd.) ali sumom nanjo.
Accidental eye exposure may occur when the dog shakes its head during or just after administration.
Do nenamerne izpostavljenosti oči lahko pride, ko pes strese z glavo med ali takoj po dajanju zdravila.
Systemic absorption of all active substances was determined in multiple-dose studies after placing the veterinary medicinal product into both ear canals of healthy mixed breed dogs.
Sistemska absorpcija vseh učinkovin je bila določena v raziskavi z večkratnim odmerjanjem, kjer so zdravilo vnesli v oba sluhovoda zdravih psov mešancev.
The formulation dissolves in ear wax and is slowly eliminated from the ear mechanically.
Zdravilo se raztopi v ušesnem maslu in se po mehanski poti počasi izloča iz ušesa.
Fertility: Do not use in breeding animals.
Plodnost: Ne uporabite pri vzrejnih živalih.
The safety of the product has not been established in dogs less than 2 months of age or weighing less than 1.4 kg.
Varnost zdravila pri psih, mlajših od dveh mesecev ali lažjih od 1,4 kg, ni bila dokazana.
Its spectrum of activity includes Gram-positive and Gram-negative bacteria including Staphylococcus pseudintermedius (MIC90 of 8 µg/ml).
Njegov spekter delovanja zajema grampozitivne in gramnegativne bakterije, vključno s Staphylococcus pseudintermedius (MIC90 8 µg/ml).
Do not use in cases of hypersensitivity to the active substances, to other corticosteroids or to any of the excipients.
Ne uporabite v primerih preobčutljivosti na učinkovine, na druge kortikosteroide ali na katerokoli pomožno snov.
Inflammation can increase the percutaneous absorption of veterinary medicinal products.
Vnetje lahko poveča perkutano absorpcijo zdravila.
In animals with a history of chronic or recurrent otitis externa, efficacy of the product may be affected if the underlying causes of the condition such as allergy or anatomical conformation of the ear are not addressed.
Pri živalih z anamnezo kroničnega ali ponavljajočega se vnetja zunanjega sluhovoda je lahko učinkovitost tega zdravila zmanjšana, če primarni vzrok, kot je npr. alergija ali anatomska zgradba ušesa, ni obravnavan.
It is recommended not to repeat ear cleaning until 21 days after the second administration of the product.
Priporoča se, da čiščenja ušes ne ponovite, dokler ne mine 21 dni od drugega dajanja zdravila.
Elanco France S.A.S., 26 Rue de la Chapelle, 68330 Huningue, France
Elanco France S.A.S., 26 Rue de la Chapelle, 68330 Huningue, Francija
Marketing authorisation holder: Elanco GmbH, Heinz-Lohmann-Str. 4, 27472 Cuxhaven, Germany
Imetnik dovoljenja za promet z zdravilom: Elanco GmbH, Heinz-Lohmann-Str. 4, 27472 Cuxhaven, Nemčija
Auricular administration of five times the recommended dose, one week apart, for 5 consecutive weeks (a total six administrations of 5 tubes per ear or 10 tubes per dog) to mixed breed dogs weighing 10 to 14 kg resulted in clinical signs of wetness of the inner and outer pinna (attributed to presence of the product).
Po avrikularni uporabi petkratnega priporočenega odmerka v razmiku enega tedna pet tednov zaporedoma (skupaj šest aplikacij petih tub v eno uho oziroma 10 tub na psa) pri psih mešancih, težkih od 10 do 14 kg, so se pojavili klinični znaki mokrote notranjega in zunanjega dela uhlja (zaradi prisotnosti zdravila).
Single-use multi-layered aluminium and polyethylene tube with a polypropylene thermoplastic elastomer tip.
Večplastna aluminijasta in polietilenska tuba za enkratno uporabo s polipropilensko termoplastično elastomerno konico.
In clinical trials, saline only was used for ear cleaning.
kliničnih raziskavah se je za čiščenje ušes uporabljala le fiziološka raztopina.
Argenta Dundee Limited, Kinnoull Road, Dunsinane Industrial Estate, Dundee DD2 3XR, UNITED KINGDOM
Argenta Dundee Limited, Kinnoull Road, Dunsinane Industrial Estate, Dundee DD2 3XR, Združeno kraljestvo
Decreased cortisol levels were observed after product instillation in tolerance studies (before and after ACTH stimulation), indicating that betamethasone is absorbed and enters the systemic circulation.
V študijah tolerance so po vkapavanju zdravila opazili zmanjšano koncentracijo kortizola (pred stimulacijo z ACTH in po njej), kar kaže na to, da se betametazon absorbira in vstopi v sistemski krvni obtok.
Auricular use.
Avrikularna uporaba.
<{MM/YYYY}> <{DD/MM/YYYY}> <{DD month YYYY}>
DATUM REVIZIJE BESEDILA {DD/MM/LLLL}
There were no clinical signs associated with unilateral vesicle formation within the epithelium of the tympanic membrane (also observed after six administrations, one week apart, of 1 tube per ear or 2 tubes per dog), unilateral mucosal ulceration in the lining of the middle ear cavity, or decrease in serum cortisol response below normal reference range in ACTH stimulation testing.
Kliničnih znakov, povezanih z enostranskim nastajanjem veziklov v epiteliju membrane bobniča (tudi po šestih aplikacijah po eno tubo na uho oziroma dve na psa v razmiku enega tedna), enostransko ulceracijo sluznice srednjega ušesa ali zmanjšanjem odziva serumskega kortizola pod normalnim referenčnim razponom pri stimulacijskem testiranju ACTH, ni bilo.
Do not use during pregnancy and lactation.
Ne uporabite v obdobju brejosti in laktacije.
Bacterial and fungal otitis is often secondary to other conditions.
Bakterijsko in glivično vnetje sluhovoda sta pogosto posledica drugih stanj.
Betamethasone is known to be teratogenic in laboratory species.
Znano je, da je betametazon za laboratorijske vrste živali teratogen.
PARTICULARS TO APPEAR ON THE OUTER PACKAGE Carton box
PODATKI NA ZUNANJI OVOJNINI Kartonska škatla
DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION Auricular use.
ODMERKI ZA POSAMEZNE ŽIVALSKE VRSTE TER POT(I) IN NAČIN UPORABE
Although a causal relationship with the veterinary medicinal product was not definitively established, owners should be recommended to monitor ocular signs (such as squinting, redness and discharge) in the hours and days following the product application, and to promptly consult a veterinarian in case such signs appear.
Čeprav vzročna povezava z zdravilom ni bila dokončno dokazana, se priporoča, da lastniki spremljajo očesne klinične znake (kot so priprte oči, pordelost in izcedek) nekaj ur in dni po dajanju zdravila in se takoj posvetujejo z veterinarjem, če se ti znaki pojavijo.
Before the veterinary medicinal product is applied, the external auditory canal must be examined thoroughly to ensure that the ear drum is not perforated.
Pred dajanjem zdravila za uporabo v veterinarski medicini je treba temeljito pregledati sluhovod, da se prepričate, da bobnič ni predrt.
Apply the product into the ear canal by pressing it between two fingers.
Zdravilo vnesite v sluhovod tako, da ga stisnete med prstoma.
Compatibility with ear cleaners, other than saline, has not been demonstrated.
Kompatibilnost s čistili za ušesa, razen s fiziološko raztopino, ni bila dokazana.
In case of accidental ocular exposure, flush the eyes thoroughly with water for 10 to 15 minutes.
V primeru, da pride do nenamerne izpostavljenosti oči, le-te temeljito spirajte z vodo 10 do 15 minut.
Due to the high antimicrobial concentrations achieved in the ear canal and the multifactorial nature of otitis externa, in vitro susceptibility may not be directly correlated with clinical success.
Zaradi visokih protimikrobnih koncentracij, doseženih v sluhovodu, in multifaktorielnih vzrokov, ki prispevajo k vnetju zunanjega sluhovoda, občutljivosti in vitro ne moremo neposredno povezati s kliničnim uspehom.
This product is a fixed combination of three active substances: antibiotic, antifungal and corticosteroid.
To zdravilo je fiksna kombinacija treh zdravilnih učinkovin: antibiotika, antimikotika in kortikosteroida.
Clean the ears before the initial treatment is applied.
Ušesa pred prvim dajanjem zdravila očistite.
Appropriate diagnosis should be used and therapy of causative conditions should be investigated before antimicrobial treatment is considered.
Pred protimikrobnim zdravljenjem je treba izvesti ustrezno diagnostiko in predvideti zdravljenje vzroka.
These findings don't affect hearing and are reversible.
Pojava ne prizadaneta sluha in sta reverzibilna.
Do not use in pregnant or breeding animals.
Ne uporabite pri brejih ali vzrejnih živalih.
Deafness or impaired hearing, usually temporary, have been reported after use in very rare cases in dogs, mainly in elderly animals, in post authorisation experience.
Glede na izkušnje po pridobitvi dovoljenja za promet so v zelo redkih primerih poročali o gluhosti ali okvari sluha, večinoma začasni, po uporabi zdravila pri psih, predvsem pri starejših živalih.
Additionally, dogs showed slightly elevated red blood cell count, hematocrit, total protein, albumin and alanine aminotransferase.
zvišane vrednosti hematokrita, skupnih beljakovin, albumina in alanin-aminotransferaze.
Prolonged or intensive use of the product may cause blistering of the tympanic membrane epithelium or mucosal ulceration in the lining of the middle ear cavity.
Dolgotrajna ali intenzivna uporaba zdravila lahko povzroči mehurje na epiteliju bobniča ali ulceracijo sluznice srednjega ušesa.
In case of accidental skin contact, wash exposed skin thoroughly with water.
V primeru nenamernega stika s kožo izpostavljeni predel temeljito sperite z vodo.
The veterinary medicinal product is a fixed combination of three active substances (corticosteroid, antifungal and antibiotic):
Zdravilo je fiksna kombinacija treh zdravilnih učinkovin (kortikosteroida, antimikotika in antibiotika):
If accidental ocular exposure does occur, the eyes should be flushed thoroughly with water for 10 to 15 minutes.
V primeru, da pride do nenamerne izpostavljenosti oči, le-te temeljito izpirajte z vodo 10 do 15 minut.
Reversibility of the epithelial tympanic membrane blistering is also likely through epithelial migration, a natural self-cleaning and self-repair mechanism for the tympanic membrane and ear canal.
Reverzibilnost pojava mehurjev na epitelni membrani bobniča je verjetno prav tako posledica epitelne migracije, ki je naravni mehanizem samoočiščenja in samoobnavljanja bobniča in sluhovoda.
Do not use in pregnant or breeding animals (see section 4.7).
Ne uporabite pri brejih ali vzrejnih živalih (glejte poglavje 4.7).
Introduce this flexible soft tip into the ear canal.
Prožno konico vstavite v sluhovod.