natgillin/translations-raw huggingface dataset:
Hypoglycaemia (low blood sugar) means that there is not enough sugar in the blood.
Hipoglikemija (nizka koncentracija krvnega sladkorja) pomeni, da v krvi ni dovolj sladkorja.
Cases of diabetic ketoacidosis have been reported when Apidra has been given in continuous subcutaneous insulin infusion in pump systems.
Primeri diabetične ketoacidoze so bili opisani, če je bilo zdravilo Apidra uporabljeno za kontinuirano subkutano infundiranje insulina v sistemih s črpalko.
Failure to follow Apidra specific instructions may lead to serious adverse events.
Neupoštevanje specifičnih navodil za zdravilo Apidra lahko povzroči resne neželene učinke.
Elderly Very limited pharmacokinetic data are available for elderly patients with diabetes mellitus.
Starejši Na voljo so le zelo omejeni podatki o farmakokinetiki pri starejših bolnikih z diabetesom mellitusom.
Apidra contains metacresol, which may cause allergic reactions.
Zdravilo Apidra vsebuje metakrezol, ki lahko povzroči alergijske reakcije.
INFORMATION IN BRAILLE Apidra
PODATKI V BRAILLOVI PISAVI Apidra
In controlled clinical studies in adults, insulin glulisine did not show differences in safety and efficacy in subgroup analyses based on race and gender.
V kontroliranih kliničnih preizkušanjih pri odraslih se varnost in učinkovitost insulina glulisin v analizah podskupin po starosti in spolu nista razlikovali.
Do not stop Apidra without speaking to a doctor, who will tell you what needs to be done.
Ne prenehajte zdravljenja z zdravilom Apidra, ne da bi se pogovorili z zdravnikom.
What Apidra looks like and contents of the pack
Izgled zdravila Apidra in vsebina pakiranja
SoloStar has to be used as recommended in these Instructions for use (see section 6.6).
SoloStar uporabljajte kot je priporočeno v navodilih za ravnanje z injekcijskim peresnikom (glejte poglavje 6.6).
Apidra contains metacresol Apidra contains metacresol, which may cause allergic reactions.
Apidra vsebuje metakrezol Zdravilo Apidra vsebuje metakrezol, ki lahko povzroči alergijske reakcije.
Read and follow the instructions that come with your insulin infusion pump.
Preberite in upoštevajte navodila, priložena vaši črpalki za infundiranje insulina.
If you forget to use Apidra
Če ste pozabili uporabiti zdravilo Apidra
They may include cold sweats, cool pale skin, fatigue, nervousness or tremor, anxiousness, unusual tiredness or weakness, confusion, difficulty in concentration, drowsiness, excessive hunger, vision changes, headache, nausea and palpitation.
Obsegajo lahko hladno znojenje, hladno in bledo kožo, izčrpanost, živčnost ali tremor, anksioznost, nenavadno utrujenost ali šibkost, zmedenost, težave s koncentracijo, zaspanost, čezmerno lakoto, spremembe vida, glavobol, navzeo in palpitacije.
The pen must not be soaked, washed or lubricated as this may damage it.
Injekcijskega peresnika ne smete namakati, umivati ali mazati, ker ga s tem lahko poškodujete.
The patient should always follow the Apidra specific instructions and always have access to alternative insulin delivery system in case of pump system failure.
Bolnik mora vedno upoštevati specifična navodila za uporabo zdravila Apidra in mora vedno imeti na voljo še drug sistem za dajanje insulina za primer, da sistem s črpalko odpove.
Continuous subcutaneous infusion pump Refer to section 4.2 and 4.4 for advice.
Stalno subkutano infundiranje s črpalko Glejte poglavji 4.2 in 4.4.
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Če ste noseči ali dojite, menite, da bil lahko bili noseči ali načrtujete zanositev, se posvetujte s svojim zdravnikom ali s farmacevtom, preden vzamete to zdravilo.
These could be symptoms of severe cases of generalised allergy to insulin, including anaphylactic reaction, which may be life-threatening.
To so lahko znaki generalizirane alergije na insulin, vključno z anafilaktično reakcijo, ki je lahko smrtno nevarna.
If you experience the following symptoms, contact your doctor immediately:
Takoj povejte zdravniku, če izkusite sledeče simptome:
If you stop using Apidra
Če ste prenehali uporabljati zdravilo Apidra
Severe cases of generalized allergy, including anaphylactic reaction, may be life-threatening.
Hudi primeri generaliziranih alergij, vključno z anafilaktičnimi reakcijami, so lahko smrtno nevarni.
A number of substances affect glucose metabolism and may require dose adjustment of insulin glulisine and particularly close monitoring.
Na presnovo glukoze vplivajo številna zdravila; potrebna utegneta biti prilagoditev odmerka insulina glulisin in posebno natančno nadziranje.
Hyperglycaemia (high blood sugar) means that there is too much sugar in the blood.
Hiperglikemija (visok krvni sladkor) pomeni, da je v krvi preveč sladkorja.
Packs of 1, 2, 4 and 5 vials are available.
Na voljo so pakiranja z 1, 2, 4 in 5 vialami.
To prevent the possible transmission of disease, each pen must be used by one patient only.
Da preprečite možen prenos bolezni, sme vsak injekcijski peresnik uporabljati samo en bolnik.
Malfunction of the insulin pump or infusion set or handling errors can rapidly lead to hyperglycaemia, ketosis and diabetic ketoacidosis.
Nepravilno delovanje insulinske črpalke ali kompleta za infundiranje, ali napake pri ravnanju lahko hitro povzročijo hiperglikemijo, ketozo in diabetično ketoacidozo.
Studies in healthy volunteers and patients with diabetes demonstrated that insulin glulisine is more rapid in onset of action and of shorter duration of action than regular human insulin when given subcutaneously.
Študije pri zdravih prostovoljcih in bolnikih z diabetesom so pokazale, da začne insulin glulisin po subkutani uporabi delovati hitreje in deluje krajši čas kot navadni humani insulin.
Continuous subcutaneous insulin infusion
Kontinuirano subkutano infundiranje insulina
Your doctor may tell you to use it in combination with an intermediate, long-acting insulin, a basal insulin or with tablets used to treat high blood sugar levels.
Zdravnik vam bo morda naročil, da ga uporabljate v kombinaciji s srednjedolgo-, dolgodelujočim insulinom, z bazalnim insulinom ali s tabletami, ki se uporabljajo za zdravljenje visokih koncentracij krvnega sladkorja.
B. Line up the needle with the pen, and keep it straight as you attach it (screw or push on,
B. Naravnajte iglo z injekcijskim peresnikom in jo držite naravnost, medtem ko jo nameščate (privijte jo ali jo potisnite, odvisno od vrste igle).
If administration by syringe, intravenous injection or infusion pump is necessary, a vial should be used (see section 4.4).
Če je potrebno dajanje z injekcijsko brizgo, intravensko injekcijo ali infuzijsko črpalko, je treba uporabiti vialo (glejte poglavje 4.4).
Recommended safety measures for removal and disposal of needles must be followed (e.g. a one handed capping technique) in order to reduce the risk of accidental needle injury and transmission of infectious diseases.
Upoštevajte priporočene varnostne ukrepe, ko igle odstranjujete in zavržete (npr. tehniko pokrivanja z eno roko), da boste zmanjšali tveganje za naključno poškodbo z iglo in prenos nalezljivih bolezni.
The distribution and elimination of insulin glulisine and regular human insulin after intravenous administration is similar with volumes of distribution of 13 l and 22 l and half-lives of 13 and 18 minutes, respectively.
Porazdelitev in izločanje insulina glulisin in navadnega humanega insulina sta po intravenski uporabi podobni: volumen porazdelitve je pri prvem 13 l in pri drugem 22 l, razpolovni čas pa pri prvem 13 minut in pri drugem 18 minut.
Read carefully the "SoloStar Instructions for use" included in this package leaflet.
Natančno preberite "Navodila za ravnanje s SoloStarjem", ki jih vključuje to navodilo.
You may need to use Apidra with syringes or pens.
Morda boste morali zdravilo Apidra uporabiti z injekcijskimi brizgami ali injekcijskimi peresniki.
In a clinical study performed in non-diabetic subjects covering a wide range of renal function (CrCl >80 ml/min, 30-50 ml/min, <30 ml/min), the rapid-acting properties of insulin glulisine were generally maintained.
V klinični študiji pri nediabetičnih preiskovancih z zelo različnim delovanjem ledvic (očistek kreatinina > 80 ml/min, 30-50 ml/min, < 30 ml/min) se je hitro delovanje insulina glulisin praviloma ohranilo.
Insulin glulisine was shown to be comparable to regular human insulin with regard to glycated haemoglobin (expressed as HbA1c equivalent) changes from baseline to the 6-month endpoint (-0.46% for insulin glulisine and -0.30% for regular human insulin, p=0.0029) and from baseline to the 12-month endpoint (-0.23% for insulin glulisine and -0.13% for regular human insulin, difference not significant).
Insulin glulisin je primerljiv navadnemu humanemu insulinu, kar zadeva spremembo glikiranega hemoglobina (izraženo kot ekvivalent HbA1c) od izhodišča do končne točke po 6-ih mesecih (-0,46 % za insulin glulisin in -0,30 % za navadni humani insulin, p = 0,0029) in od izhodišča do končne točke po 12-ih mesecih (-0,23 % za insulin glulisin in -0,13 % za navadni humani insulin, razlika ni značilna).
They can also spread around the injection site.
Te reakcije se lahko razširijo tudi okoli mesta injiciranja.
Comparable self-monitored blood glucose values were observed.
Ugotovili so tudi primerljive vrednosti glukoze v krvi, izmerjene s samokontrolo.
Check the insulin A. Check the label on your SoloStar to make sure you have the correct insulin.
A. Preverite nalepko na injekcijskem peresniku SoloStar, da se boste prepričali, ali imate pravi insulin.
When insulin glulisine is injected subcutaneously, the glucose lowering activity will begin within 10-20 minutes.
Po subkutanem injiciranju insulina glulisin se učinek na zniževanje glukoze pojavi v 10 do 20 minutah.
• Always have a spare SoloStar in case your SoloStar is lost or damaged.
• Vedno imejte na zalogi rezerven SoloStar, če injekcijski peresnik izgubite ali se poškoduje.
There are no or limited amount of data (less than 300 pregnancy outcomes) from the use of insulin glulisine in pregnant women.
Podatkov o uporabi insulina glulisin pri nosečnicah ni oziroma so na voljo le omejene količine podatkov (manj kot 300 izidov nosečnosti).
Administered immediately before a test meal, insulin glulisine provided better postprandial control than regular human insulin, as in adults (see section 5.1).
Insulin glulisin, apliciran tik pred testnim obrokom, je zagotovil boljšo postprandialno urejenost kot navadni humani insulin, tako kot pri odraslih (glejte poglavje 5.1).
GLULISINE LISPRO REGULAR
GLULISIN LISPRO NAVADNI
Apidra should be used at a concentration of 1 Unit/ml insulin glulisine in infusion systems with sodium chloride 9 mg/ml (0.9%) solution for infusion with or without 40 mmol/l potassium chloride using coextruded polyolefin/polyamide plastic infusion bags with a dedicated infusion line.
Zdravilo Apidra je treba v koncentraciji 1 enota/ml insulina glulisin uporabiti v infuzijskih sistemih z 0,9 % (9 mg/ml) raztopino natrijevega klorida za infundiranje, s 40 mmol/l kalijevega klorida ali brez njega, ter z uporabo koekstrudiranih plastičnih infuzijskih vrečk iz poliolefina/poliamida in namensko infuzijsko linijo.
METHOD AND ROUTE(S) OF ADMINISTRATION Subcutaneous use.
POSTOPEK IN POT(I) UPORABE ZDRAVILA Za subkutano uporabo.
A phase I study carried out with insulin glulisine, lispro and regular human insulin in an obese population has demonstrated that insulin glulisine maintains its rapid-acting properties.
Študija faze I, opravljena z insulinom glulisin, insulinom lispro in navadnim humanim insulinom pri populaciji debelih preiskovancev, je pokazala, da insulin glulisin ohrani svoje hitro delovanje.
The label on the pen should be checked to make sure it contains the correct insulin.
Preveriti morate oznako na injekcijskem peresniku in se tako prepričati, da vsebuje pravi insulin.
The time to 10% of total INS exposure was reached earlier by approximately 5-6 min with insulin glulisine.
Z insulinom lispro je bila 10 % skupna INS izpostavljenost dosežena približno 5-6 minut hitreje.
If SoloStar is in cool storage, it should be taken out 1 to 2 hours before you inject to allow it to warm up.
Če je SoloStar shranjen na hladnem, ga morate vzeti iz hladilnika 1 do 2 uri pred injiciranjem, da se ogreje.
OTHER SPECIAL WARNING(S), IF NECESSARY Use only clear and colourless solutions.
DRUGA POSEBNA OPOZORILA, ČE SO POTREBNA Raztopino uporabite le, če je bistra in brezbarvna.
After removing the pen cap, the appearance of insulin should also be checked: the insulin solution must be clear, colourless, with no solid particles visible, and must have a water-like consistency.
Po odstranitvi pokrovčka injekcijskega peresnika je treba preveriti videz insulina: raztopina insulina mora biti bistra, brezbarvna, brez vidnih delcev in vodi podobne konsistence.
Hydrochloric acid, concentrated Sodium hydroxide Water for injections
koncentrirana klorovodikova kislina, natrijev hidroksid, voda za injekcije.
Figure 2: Glucose infusion rates (GIR) after subcutaneous injection of 0.3 Units/kg of insulin glulisine (GLULISINE) or insulin lispro (LISPRO) or regular human insulin (REGULAR) in an obese population.
Slika 2: Hitrost infundiranja glukoze (GIR) po subkutani injekciji 0,3 enot/kg insulina glulisin (GLULISIN) ali insulina lispro (LISPRO) ali navadnega humanega insulina (NAVADNI) pri debelih preiskovancih.
When insulin glulisine was injected subcutaneously into abdomen, deltoid and thigh, the concentration-time profiles were similar with a slightly faster absorption when administered in the abdomen compared to the thigh.
Po subkutanem injiciranju insulina glulisin v trebuh, deltoidni predel in stegno je bil profil časovnega poteka koncentracije podoben, z nekoliko hitrejšo absorpcijo po aplikaciji v trebuh kot po aplikaciji v stegno.
Apidra should be given by subcutaneous injection shortly (0-15 min) before or soon after meals or by continuous subcutaneous pump infusion.
Zdravilo Apidra se uporablja v subkutani injekciji tik (0-15 minut) pred obroki ali kmalu po njih ali stalni subkutani infuziji s črpalko.
When mixed with NPH human insulin, Apidra should be drawn into the syringe first.
V primeru mešanja s humanim insulinom NPH, je treba insulin Apidra v brizgo potegniti najprej.
Before using Apidra in the pump system you should have been given detailed instructions on how to use the pump system.
Preden insulin Apidra uporabite v sistemu s črpalko, morate dobiti izčrpna navodila o uporabi črpalke.
A. Use the injection method as instructed by your doctor, pharmacist or nurse.
A. Uporabite postopek injiciranja, ki vam ga je pokazal vaš zdravnik, farmacevt ali medicinska sestra..
Important information about some of the ingredients of Apidra This medicine contains less than 1 mmol (23 mg) sodium per dose, i.e. it is essentially ‘sodium-free'.
Pomembne informacije o nekaterih sestavinah zdravila Apidra To zdravilo vsebuje manj kot 1 mmol (23 mg) natrija na odmerek, kar v bistvu pomeni brez natrija.
Breast-feeding mothers may require adjustments in insulin dose and diet.
Pri doječih materah utegne biti potrebna prilagoditev odmerka insulina in prehrane.
What Apidra is and what it is used for
Kaj je zdravilo Apidra in za kaj ga uporabljamo
What Apidra is and what it is used for What you need to know before you use Apidra How to use Apidra
Kaj je zdravilo Apidra in za kaj ga uporabljamo Kaj morate vedeti, preden boste uporabili zdravilo Apidra Kako uporabljati zdravilo Apidra Možni neželeni učinki
Figure 3: Pharmacokinetic profile of insulin glulisine and regular human insulin in type 1 diabetes mellitus patients after a dose of 0.15 Units/kg.
Slika 3: Farmakokinetične značilnosti insulina glulisin in navadnega humanega insulina pri bolnikih z diabetesom mellitusom tipa 1 po odmerku 0,15 enot/kg.
How to use Apidra
Kako uporabljati zdravilo Apidra
If you inject your insulin too often at the same skin site, fatty tissue under the skin at this site may either shrink or thicken.
Če si insulin prepogosto injicirate na isto mesto, lahko podkožno maščevje na tem mestu bodisi izgine ali se zadebeli.
To ensure you get the accurate dose, the Apidra cartridges are to be used only with the following pens: - JuniorSTAR which delivers doses in steps of 0.5 units - ClikSTAR, Tactipen, Autopen 24, AllStar or AllStar PRO which deliver doses in steps of 1 unit.
Da zagotovite, da prejmete pravilen odmerek, vložke zdravila Apidra uporabljajte samo s sledečimi injekcijskimi peresniki: - JuniorSTAR, s katerim odmerjamo v korakih po 0,5 enot - ClikSTAR, Tactipen, Autopen 24, AllStar ali AllStar PRO, s katerimi odmerjamo v korakih po 1 enoto.
Conditions which may make the early warning symptoms of hypoglycaemia different or less pronounced include long duration of diabetes, intensified insulin therapy, diabetic nerve disease, medicinal products such as beta blockers or after transfer from animal-source insulin to human insulin.
Med stanji, ki lahko spremenijo zgodnje opozorilne simptome hipoglikemije ali zmanjšajo njihovo izrazitost, so dolgotrajen diabetes, intenzivirano zdravljenje z insulinom, diabetična nevropatija, zdravila, kakršna so zaviralci adrenergičnih receptorjev beta, ali prehod z insulina živalskega izvora na humani insulin.
In this study, the time to 20% of total AUC and the AUC (0-2h) representing the early glucose lowering activity were respectively of 114 minutes and 427 mg/kg for insulin glulisine, 121 minutes and 354 mg/kg for lispro, 150 minutes and 197 mg/kg for regular human insulin (see figure 2).
V tej študiji sta bila čas do 20 % celotne AUC in AUC (0-2h), ki predstavljata zgodnji učinek na znižanje glukoze, pri insulinu glulisin 114 minut in 427 mg.kg-1, pri insulinu lispro 121 minut in 354 mg.kg-1 in pri navadnem humanem insulinu 150 minut in 197 mg.kg-1 (slika 2).
Read carefully all of this leaflet including the Instructions for Use of Apidra SoloStar, pre-filled pen, before using this medicine because it contains important information for you.
Pred začetkom uporaboe zdravila natančno preberite navodilo, vključno z navodilom za ravnanje z zdravilom Apidra SoloStar napolnjen injekcijski peresnik, ker vsebuje za vas pomembne podatke!
Type 2 diabetes mellitus-Adults
Diabetes mellitus tipa 2 - odrasli
Inspect the vial before use.
Vialo pred uporabo preglejte.
If the insulin pen is damaged or not working properly (due to mechanical defects) it has to be discarded, and a new insulin pen has to be used.
Če je injekcijski peresnik poškodovan ali ne deluje pravilno (zaradi mehanskih poškodb), ga zavrzite in uporabite nov injekcijski peresnik.
Apidra 100 Units/ml solution for injection in a vial: Most of the cases were related to handling errors or pump system failure when Apidra was used with CSII.
(2) Apidra 100 enot/ml raztopina za injiciranje v viali: Večina teh primerov je bila povezana z napakami pri ravnanju ali z odpovedjo sistema s črpalko, če je bilo zdravilo Apidra uporabljeno s CSII.
Beta-blockers, clonidine, lithium salts or alcohol may either potentiate or weaken the blood-glucose-lowering activity of insulin.
Zaviralci adrenergičnih receptorjev beta, klonidin, litijeve soli ali alkohol lahko učinek znižanja glukoze v krvi pri insulinu bodisi stopnjujejo ali oslabijo.
There are no or limited data on the use of Apidra in pregnant women.
Podatkov o uporabi zdravila Apidra pri nosečnicah ni oziroma so omejeni.
What you need to know before you use Apidra
Kaj morate vedeti preden boste uporabili zdravilo Apidra
Always use a new sterile needle for each injection.
Za vsako injiciranje vedno uporabite novo, sterilno iglo.
Generalised allergy to insulin: Associated symptoms may include large-scale skin reactions (rash and itching all over the body), severe swelling of skin or mucous membranes (angioedema), shortness of breath, a fall in blood pressure with rapid heartbeat and sweating.
Generalizirane alergije na insulin: skupni simptomi vključujejo obsežne kožne reakcije (izpuščaj in srbenje po celem telesu), huda oteklina kože ali sluznic (angioedem), oteženo dihanje, znižanje krvnega tlaka s hitrim bitjem srca in znojenje.
Figure 1A
slika 1 A
B. Dispose of the needle safely, as instructed by your doctor, pharmacist or nurse.
B. Iglo varno zavrzite, kot vam je naročil vaš zdravnik, farmacevt ali medicinska sestra..
Do not put SoloStar next to the freezer compartment or a freezer pack.
Ne shranjujte SoloStarja v bližini zamrzovalnega razdelka ali zamrzovalnega vložka.
GLUCOSE - mg/dL
GLUKOZA V KRVI - mg/dl
Deterioration of renal function may lead to a decrease in insulin requirements.
Lahko pa napredujoče slabšanje delovanja ledvic povzroči zmanjšanje potrebe po insulinu.
Apidra must not be mixed with glucose or Ringer's solution or with any other insulin.
Zdravila Apidra se ne sme mešati z raztopino glukoze, Ringerjevo raztopino ali s katerimkoli drugim insulinom.
A phase I study in 18 obese patients with type 2 diabetes mellitus (BMI between 35 and 40 kg/m2) with insulin glulisine and insulin lispro [90% CI: 0.81, 0.95 (p=<0.01)] has shown that insulin glulisine effectively controls diurnal postprandial blood glucose excursions.
Študija faze I, izvedena pri 18 bolnikih s prekomerno telesno maso in diabetesom mellitusom tipa 2 (indeks telesne mase med 35 in 40 kg/m2) z insulinom glulisin in insulinom lispro [90 % interval zaupanja: 0,81; 0,95 (p = < 0,01)] je pokazala, da insulin glulisin učinkovito nadzira dnevno postprandialno nihanje glukoze v krvi.
Step 2.
Nastavite odmerek 2.
Subcutaneous use Abbreviation authorised for multilingual pack
Kratica odobrena za večjezično ovojnino.
Apidra 100 Units/ml solution for injection in a vial Cases of hyperglycaemia have been reported with Apidra when used with CSII (see section 4.4) that has led to Diabetic Ketoacidosis (DKA); most of the cases were related to handling errors or pump system failure.
Med uporabo zdravila Apidra v CSII so bili opisani primeri hiperglikemije (glejte poglavje 4.4), ki so povzročili diabetično ketoacidozo (DKA); večina primerov je bila povezana z napakami pri ravnanju ali z odpovedjo sistema s črpalko.
Apidra must not be mixed with any preparation other than NPH human insulin.
Zdravila Apidra ne smete mešati z nobenim drugim preparatom kot s humanim insulinom NPH.
For more information on signs and symptoms of hyperglycaemia refer to the box at the end of this leaflet.
Za več informacij o znakih in simptomih hiperglikemije glejte okvirček na koncu tega navodila.
The pharmacokinetic properties of insulin glulisine are generally maintained in patients with renal impairment.
Farmakokinetične lastnosti insulina glulisin se pri bolnikih z okvaro ledvic praviloma ohranijo.
In an across study analysis of insulin glulisine in either healthy subjects or subjects with type 1 or type 2 diabetes mellitus the apparent half-life ranged from 37 to 75 minutes (interquartile range).
V analizi prečne študije insulina glulisin pri zdravih preiskovancih ali preiskovancih z diabetesom mellitusom tipa 1 ali tipa 2 je bil navidezni razpolovni čas od 37 do 75 minut (interkvartilni razpon).
One unit of insulin glulisine has the same glucose-lowering activity as one unit of regular human insulin.
Ena enota insulina glulisin ima enak hipoglikemičen učinek kot ena enota navadnega humanega insulina.
Patients using continuous subcutaneous insulin infusion pump therapy must be trained to administer insulin by injection and have alternative insulin delivery system available in case of pump system failure (see section 4.2 and 4.8).
Bolnike, ki uporabljajo zdravljenje s kontinuiranim subkutanim infundiranjem insulina, je treba usposobiti za uporabo insulina z injiciranjem in na voljo morajo imeti še drug sistem za dajanje insulina za primer, da sistem s črpalko odpove (glejte poglavji 4.2 in 4.8).
In the per-protocol population there was a significantly larger observed reduction in GHb in the pre-meal glulisine group compared with the regular insulin group.
V populaciji po-protokolu so v skupini, ki je uporabljala glulisin pred obrokom, ugotovili značilno večje znižanje vrednosti glikiranega hemoglobina kot v skupini, ki je uporabljala navadni insulin.