natgillin/translations-raw huggingface dataset:
The safety of the vaccine was studied in an overdose laboratory safety study carried out with BTVPUR AlSap 2-4 in sheep.
Varnost cepiva je bila raziskana v laboratorijskih študijah varnosti prevelikega odmerjanja z uporabo cepiva BTVPUR AlSap 2-4 pri ovcah.
Bluetongue vaccine serotype 2 and 4
Cepivo proti bolezni modrega jezika, serotip 2 in 4
The studies on the monovalent vaccines containing bluetongue virus serotypes 2 or 4 showed that the period of protection is 12 months for both serotypes.
Študije monovaletnih cepiv z virusom modrega jezika serotipa 2 ali 4 so pokazale, da zaščita pri obeh serotipih traja 12 mesecev.
BTVPUR AlSap 2-4 contains bluetongue viruses of two types (serotypes 2 and 4).
Zdravilo BTVPUR AlSap 2-4 vsebuje dva tipa virusov modrega jezika (serotipa 2 in 4).
The CVMP concluded that the benefits of BTVPUR AlSap 2-4 exceed the risks for active immunisation of sheep to prevent infection, viraemia and clinical signs caused by the bluetongue virus serotypes 2 and 4, and recommended that BTVPUR AlSap 2-4 be given marketing authorisation.
Odbor za zdravila za uporabo v veterinarski medicini (CVMP) je zaključil, da so koristi cepiva BTVPUR AlSap 2-4 za aktivno imunizacijo ovac za preprečitev okužbe, viremije in kliničnih znakov, ki jih povzročata serotipa 2 in 4 virusa bolezni modrega jezika, večje od z njim povezanih tveganj, in priporočil, da se zanj odobri dovoljenje za promet.
Protection starts three and five weeks after the injection for serotype 4 and serotype 2, respectively.
Zaščita nastopi tri tedne po cepljenju za serotip 4 in pet tednov po cepljenju za serotip 2.
Results also from a series of laboratory safety trials performed with vaccines of similar composition but including only one of the two serotypes of BTVPUR AlSap 2-4 or different bluetongue serotypes were presented in order to extrapolate safety conclusions.
Predstavljeni so bili tudi rezultati niza laboratorijskih preskušanj varnosti z uporabo cepiva s podobno sestavo, ki pa je vsebovalo bodisi le enega od dveh serotipov cepiva BTVPUR AlSap 2-4 bodisi različne serotipe bolezni modrega jezika, da bi tako pridobili zaključke o varnosti.
The company also presented results from a series of trials conducted with vaccines of similar composition but including only one of the two serotypes of BTVPUR AlSap 2-4 in order to extrapolate further efficacy conclusions.
Družba je predstavila tudi rezultate niza preskušanj cepiv podobne sestave, ki vsebujejo le enega od dveh serotipov zdravila BTVPUR AlSap 24, da bi tako pridobili nadaljnje zaključke o učinkovitosti.
BTVPUR AlSap 2-4 contains bluetongue viruses that have been inactivated so that they cannot cause the disease.
Cepivo BTVPUR AlSap 2-4 vsebuje inaktivirane viruse modrega jezika, ki ne povzročajo bolezni.
What benefit has BTVPUR AlSap 2-4 shown during the studies?
Kakšne koristi je zdravilo BTVPUR AlSap 2-4 izkazalo med študijami?
Other information about BTVPUR AlSap 2-4:
Druge informacije o zdravilu BTVPUR AlSap 2-4:
BTVPUR ALSap 2-4 is used in sheep to protect them against bluetongue disease, an infection caused by the bluetongue virus which is transmitted by midges.
Cepivo BTVPUR ALSap 2-4 se uporablja pri ovcah za zaščito pred boleznijo modrega jezika, tj. okužbo, ki jo povzroča virus modrega jezika, prenašajo pa jo krvosesi insekti.
Two further studies were conducted to determine the period of protection of the monovalent vaccines each containing either bluetongue virus serotype 2 or 4 respectively.
Dve dodatni študiji sta bili izvedeni, da bi določili obdobje zaščite, ki ga nudita monovalentni cepivi, od katerih eno vsebuje virus modrega jezika serotip 2, drugo pa serotip 4.
BTVPUR AlSap 2-4 is a vaccine.
BTVPUR AlSap 2-4 je cepivo.
Two more laboratory studies with BTVPUR AlSap 2-4 were presented to support the efficacy of the vaccine.
V podporo učinkovitosti cepiva sta bili predstavljeni dve nadaljnji laboratorijski študiji s cepivom BTVPUR AlSap 2-4.
What is the risk associated with BTVPUR AlSap 2-4?
Kakšna tveganja so povezana z zdravilom BTVPUR AlSap 2-4?
Why has BTVPUR AlSap 2-4 been approved?
Zakaj je bilo zdravilo BTVPUR AlSap 2-4 odobreno?
In both studies lambs were exposed to either bluetongue virus serotype 2 or bluetongue virus serotype 4, 12 months after vaccination.
V obeh študijah so bila jagnjeta 12 mesecev po cepljenju izpostavljena bodisi virusu modrega jezika serotipa 2 bodisi virusu modrega jezika serotipa 4.
What is BTVPUR AlSap 2-4?
Kaj je zdravilo BTVPUR AlSap 2-4?
What is BTVPUR AlSap 2-4 used for?
Za kaj se zdravilo BTVPUR AlSap 2-4 uporablja?
The virus exists in several forms (serotypes) throughout the world; the types used in BTVPUR Alsap 2-4 are serotypes 2 and 4.
Virus obstaja v različnih oblikah (serotipih) po vsem svetu.
How has BTVPUR AlSap 2-4 been studied?
Kako je bilo zdravilo BTVPUR AlSap 2-4 raziskano?
This means that it was not possible to obtain complete information about BTVPUR AlSap 2-4 at the time of the initial authorisation.
To pomeni, da ob prvotni odobritvi ni bilo mogoče pridobiti vseh podatkov o njem.
Incompatibilities None known.
Inkompatibilnosti Niso znane.
Please carefully follow the instructions of the veterinarian.
Upoštevajte navodila veterinarja.
Five major metabolites have been identified.
Zaznali so pet glavnih presnovkov.
Reduction of post-operative pain (over a period of 24 hours):
Zmanjševanje pooperativne bolečine ( čez obdobje 24 ur ):
The active substance in Meloxidyl is an allowed substance as described in table 1 of the annex to Commission Regulation (EU) No 37/2010:
Zdravilna učinkovina v zdravilu Meloxidyl je dovoljena učinkovina, kot je navedena v tabeli 1 (dovoljene snovi) priloge Uredbe Komisije (EU) št. 37/2010:
One ml contains:
1 ml vsebuje:
Lungomare Pirandello, 8 92014 Porto Empedocle (AG) Italy
Lungomare Pirandello, 8 92014 Porto Empedocle (AG) Italija
The excipients listed in section 6.1 of the SPC are either allowed substances for which table 1 of the annex to Commission Regulation (EU) No 37/2010 indicates that no MRLs are required or are considered as not falling within the scope of Regulation (EC) No 470/2009 when used as in this veterinary medicinal product.
Za pomožne snovi, navedene v poglavju 6.1 SPC , tabela 1 (dovoljene snovi) priloge Uredbe Komisije (EU) št.37/2010 določa, da MRL ni potreben ali pa, kot so uporabljene v tem zdravilu za uporabo v veterinarski medicini, niso vključene v Uredbo(ES) št. 470/2009.
If the animal is fed at the time of dosing, the absorption may be slightly delayed.
Če žival ob prejemu zdravila ni tešča, je lahko absorpcija nekoliko odložena.
Detailed information on this veterinary medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu/.
Podrobne informacije o tem zdravilu za uporabo v veterinarski medicini so na voljo na spletni strani Evropske agencije za zdravila http://www.ema.europa.eu/.
Treatment of calves with Meloxidyl 20 minutes before dehorning reduces post-operative pain.
Zdravljenje telet z zdravilom Meloxidyl 20 minut pred odstranitvijo rogov zmanjša pooperativno bolečino.
21% of the recovered dose is eliminated in urine (2% as unchanged meloxicam, 19% as metabolites) and 79% in the faeces (49% as unchanged meloxicam, 30% as metabolites).
21% vnesenega odmerka se odstrani iz telesa z urinom (2 % v obliki nespremenjenega meloksikama, 19 % v obliki presnovkov) in 79 % z blatom (49 % v obliki nespremenjenega meloksikama, 30 % v obliki presnovkov).
Name and address of the manufacturer of the biological active substances Not applicable.
Ime in naslov proizvajalca(proizvajalcev) biološke (bioloških)učinkovine (učinkovin) Ni smiselno.
Reduction of post-operative pain:
Zmanjševanje pooperativne bolečine:
The oral follow-up dose may be administered once daily (at 24 hour intervals) for up to four days.
Peroralni nadaljevalni odmerek lahko dajemo enkrat na dan (v 24-urnih presledkih) največ do štiri dni.
Oral suspension.
Bledorumena suspenzija.
The recommended dose should not be exceeded.
Ne prekoračite priporočenega odmerjanja.
If you notice any side effects, even those not already listed in this package leaflet or you think that the medicine has not worked, please inform your veterinary surgeon .
Če opazite kakršne koli stranske učinke, tudi tiste, ki niso navedeni v tem navodilu za uporabo ali mislite, da zdravilo ni delovalo, obvestite svojega veterinarja.
Thus, for the first day, twice the maintenance volume will be required.
Prvi dan zdravljenja je torej potreben dvakratni volumen vzdrževalnega odmerka.
In case of overdose, adverse reactions, as listed in Section 4.6, are expected to be more severe and more frequent.
V primeru prevelikega odmerka so neželeni učinki navedeni v poglavju 4.6 lahko močnejši in pogostejši.
Do not use in horses producing milk for human consumption.
Ni dovoljena uporaba pri konjih, katerih mleko je namenjeno prehrani ljudi.
As for other species investigated, the main pathway of meloxicam biotransformation in cat is oxidation and there are no pharmacologically active metabolites.
Tako kot pri drugih raziskanih vrstah, je glavna pot biološke transformacije meloksikama pri mačkah oksidacija in ni farmakološko aktivnih presnovkov.
To be administered orally either mixed with food or directly into the mouth.
Zdravilo dajemo peroralno pomešano s hrano ali direktno v gobec živali.
Meloxicam has a narrow therapeutic safety margin in cats and clinical signs of overdose may be seen at relatively small overdose levels.
Meloksikam ima ozko mejo terapevtske varnosti pri mačkah in se lahko klinični znaki prevelikega odmerka pojavijo že pri relativno nizkem prekoračenju odmerka.
Do not store above 25° C.
Ne shranjujte pri temperaturi nad 25 °C
Date of first authorisation: 15.01.2007 Date of last renewal: 19.12.2011
Datum podaljšanja dovoljenja za promet: 19.12.2011
Meloxidyl alone will not provide adequate pain relief during dehorning procedure.
Samo zdravilo Meloxidyl ne zagotavlja ustreznega lajšanja bolečine med samim postopkom odstranjevanja rogov.
Two measuring syringes are provided per each presentation.
V vsakem pakiranju sta priloženi dve merilni brizgi.
Material of the primary container
Material primarne ovojnine
Do not store above 25°C.
Ne shranjujte pri temperaturi nad 25 C
Cattle, pigs and horses
Govedo, prašiči in konji.
The metabolism in horses has not been investigated.
Presnova pri konjih ni bila ugotavljana.
D. OTHER CONDITIONS AND REQUIREMENTS OF THE MARKETING AUTHORISATION
DRUGI POGOJI IN ZAHTEVE DOVOLJENJA ZA PROMET Z ZDRAVILOM>
For post-operative pain relief in cats, safety has only been documented after thiopental/halothane anaesthesia.
Pri lajšanju pooperativnih bolečin pri mačkah je varnost uporabe zdravila dokumentirana samo po narkozi z tiopentalom/halotanom.
The volume of distribution is 0.3 l/kg in dogs and 0.09 l/kg in cats.
Porazdelitveni volumen je 0,3 l/kg pri psih in 0,09 l/kg pri mačkah.
Ceva Santé Animale ensures that the system of pharmacovigilance, as described in Part I of the marketing authorisation application, is in place and functioning before and whilst the veterinary medicinal product is on the market.
D. DRUGI POGOJI IN ZAHTEVE DOVOLJENJA ZA PROMET Z ZDRAVILOM Ceva Santé Animale zagotavlja, da je sistem farmakovigilance, predložen kot je opisan v delu I vloge za pridobitev dovoljenja za promet, vzpostavljen in deluje, preden je zdravilo v prometu in ves čas trženja zdravila.
Meloxicam is eliminated with a half-life of 24 hours in dogs and 15 hours in cats.
Razpolovna doba izločanja meloksikama je 24 ur pri psih in 15 ur pri mačkah.
If the animal is fasted when dosed, the maximal plasma concentrations are obtained after approximately 3 hours.
Če je žival ob prejemu zdravila tešča, je največja koncentracija v plazmi dosežena v približno 3 urah.
Meloxicam also has anti-endotoxic properties because it has been shown to inhibit production of thromboxane B2 induced by E. coli endotoxin administration in calves, lactating cows and pigs.
Deluje tudi antiendotoksično, saj so dokazali, da zavira nastajanje tromboksana B2, izzvano z vnosom endotoksina E. coli pri teletih, kravah v laktaciji in prašičih.
The detection of metabolites from the parent compound in urine and faeces, but not in plasma is indicative for their rapid excretion.
Dejstvo, da so presnovke matične spojine odkrili v urinu in blatu, ne pa tudi v plazmi, kaže na hitro izločanje presnovkov.
Post-operative pain and inflammation following surgical procedures: In case additional pain relief is required, multimodal pain therapy should be considered.
Postoperativna bolečina in vnetje po kirurških postopkih: Če je potrebno dodatno lajšanje bolečine, je treba razmisliti o zdravljenju z dodatnim zdravilom.
In case of overdose, adverse reactions, as listed in Section “Adverse reactions” are expected to be more severe and more frequent.
V primeru prevelikega odmerka so neželeni učinki navedeni v poglavju ''Neželeni učinki'' lahko močnejši in pogostejši.
The safety of the veterinary medicinal product has not been established during pregnancy and lactation (See section 4.3).
Varnost zdravila med brejostjo in laktacijo ni raziskana (glejte 4.3).
Très le Bois - 22600 Loudéac - France Vetem SpA - Lungomare Pirandello, 8 - 92014 Porto Empedocle (AG) - Italy
Très le Bois - 22600 Loudeac - Francija VETEM SpA - Lungomare Pirandello, 8 - 92014 Porto Empedocle (AG) - Italija Meloxidyl 5 mg/ml
Musculo-skeletal disorders: single subcutaneous injection.
Mišično - skeletna obolenja: enkratna podkožna injekcija.
A. MANUFACTURER OF THE BIOLOGICAL ACTIVE SUBSTANCES AND
A. PROIZVAJALEC (PROIZVAJALCI) BIOLOŠKE (BIOLOŠKIH) UČINKOVINE
The suspension could be administered using the smallest syringe for dogs less than 7 kg body weight (one graduation corresponding to 0.5 kg of body weight) or the largest syringe for dogs over than 7 kg body weight (one graduation corresponding to 2.5 kg of body weight).
Suspenzijo lahko dajemo z manjšo brizgo za pse s telesno maso pod 7 kilogramov ( ena graduacija ustreza 0.5 kg telesne mase) ali veliko brizgo za pse s telesno maso nad 7 kilogramov (ena graduacija ustreza 2.5 kg telesne mase).
Colourless type I glass injection vial of 10 ml, closed with a grey EPDM (Ethylene Propylene Diene Monomer) or flurotec rubber stopper and sealed with a flip off aluminium violet seal in a cardboard box.
Viala 10 ml iz brezbarvnega stekla, vrste I, s sivim EPDM (etilen propildien monomernim) ali flurotek gumijastim zamaškom in zapečatena z vijoličastim aluminijastim pečatom v kartonski škatli.
To avoid introduction of external contaminants during use, do not remove the bottle insert and keep the provided syringes only for this product.
Pazite, da med uporabo ne bi prišlo do kontaminacije, zato ne odstranjujte zaščitnega pokrovčka in uporabljajte priloženo merilno brizgo samo za to zdravilo.
4.7 Use during pregnancy, lactation or lay
4.7 Uporaba v obdobju brejosti, laktacije ali valjenja
In cattle and pigs, subcutaneous, intramuscular as well as intravenous administration is well tolerated; only a slight transient swelling at the injection site following subcutaneous administration was observed in less than 10 % of the cattle treated in clinical studies.
Živali podkožno, intramuskularno in intravensko dajanje dobro prenašajo; v kliničnih raziskavah so zasledili samo blago in prehodno oteklino na mestu podkožne injekcije, in sicer pri manj kot 10 % goved.
Ethanol anhydrous Poloxamer 188 Glycofurol Meglumine Glycine
Etanol, brezvodni Poloksamer 188 Glikofurol Meglumin Glicin
The suspension can be given using the measuring syringe provided in the package.
Suspenzijo lahko dajemo z merilno brizgo, ki je priložena pakiranju.
Clear, yellow solution.
Prozorna, rumena raztopina.
Reduction of post-operative pain (over a period of 24 hours): single intravenous or subcutaneous injection before surgery, for example at the time of induction of anaesthesia.
Zmanjševanje pooperativne bolečine ( čez obdobje 24 ur ): enkratna intravenska ali podkožna injekcija pred operacijo, npr. istočasno z indukcijo anestezije.
A clinical response is normally seen within 7 days.
Klinični odziv na zdravljenje je običajno opazen v 7 dneh.
10, 32 or 100 ml bottle with two syringes per presentation.
10, 32 ali 100 ml plastenka z dvema merilnima brizgama v vsakem pakiranju.
Très le Bois - 22600 Loudéac - France
Très le Bois - 22600 LoudéacFrancija
Depress the plunger to empty the contents of the syringe onto the food.
S pritiskom na bat brizge izpraznite vsebino v posodo s hrano vašega psa.
Chronic musculoskeletal disorders: Response to long-term therapy should be monitored at regular intervals by a veterinary surgeon.
Kronična mišično-skeletna obolenja: Pri dolgotrajni uporabi zdravila je potreben reden nadzor veterinarja.
Cattle: meat and offal: 15 days; milk: 5 days Pigs: meat and offal: 5 days Horses: meat and offal: 5 days
Govedo: Meso in organi: 15 dni; Mleko: 5 dni Prašiči: Meso in organi: 5 dni Konji: Meso in organi: 5 dni
Sodium benzoate (E 211)
Pomožna (e) snov (i) Natrijev benzoat (E 211)
Manufacturer responsible for batch release: Ceva Santé Animale - Z.I.
Proizvajalec odgovoren za sproščanje serij:Ceva Santé Animale - Z.I.
In case of inadequate relief of pain when used in the treatment of equine colic, careful re-evaluation of the diagnosis should be made as this could indicate the need for surgical intervention.
V primeru neučinkovanja pri uporabi ob sumu na koliko pri konju, je potrebno ponovno oceniti zdravstveno stanje živali, saj je lahko to znak za potrebo po kirurški intervenciji.
Horses: See section "Contraindications".
Konji: Glejte poglavje »Kontraindikacije«
In very rare cases anaphylactoid reactions may occur and should be treated symptomatically.
V zelo redkih primerih lahko pride do anafilaktične reakcije, kar zdravimo simptomatsko.
Do not use in horses less than 6 weeks of age.
Ne uporabljajte pri konjih mlajših od 6 tednov.
Cattle: Subcutaneous or Intravenous use Pigs: Intramuscular use Horses: Intravenous use Read the package leaflet before use.
Govedo: subkutano ali intravensko dajanje Prašiči: intramuskularno dajanuje Konji: intravensko dajanuje Pred uporabo preberite navodilo za uporabo.
A clinical response is normally seen within 3 - 4 days.
Klinični odziv na zdravljenje je običajno opazen po 3 - 4 dneh.
Dosing procedure using the measuring syringe:
Proces odmerjanja s priloženo merilno brizgo :
Pharmacotherapeutic group: Antiinflammatory and antirheumatic products, non-steroids (oxicams) ATC-vet code: QM01AC06
Farmakoterapevtska skupina: protivnetna in protirevmatična zdravila, nesteroidna (oksikami) ATC vet: QM01AC06
EXP Once broached, use within 28 days.
EXP Načeto zdravilo uporabite v 28 dneh
• Pre-treatment with anti-inflammatory substances may result in additional or increased adverse effects and accordingly a treatment-free period with such drugs should be observed for at least 24 hours before commencement of treatment.
• Predhodno zdravljenje z zdravili s protivnetnim delovanjem lahko povzroči dodatne neželene učinke ali jih okrepi, zato teh zdravil ne smemo dajati najmanj 24 ur pred začetkom zdravljenja.
- Do not use in animals less than 6 weeks of age nor in cats of less than 2 kg.
- Ne uporabite pri živalih mlajših od 6 tednov ali pri mačkah s telesno maso pod 2 kg.
In horses, after intravenous injection meloxicam is eliminated with a terminal half-life of 8.5 hours.
Pri konjih po intravenski aplikaciji je razpolovna doba meloksikama 8,5 ure.
Meloxicam is eliminated with a half-life of 26 hours and 17.5 hours after subcutaneous injection in young cattle and lactating cows, respectively.
Razpolovna doba izločanja meloksikama je po podkožni injekciji 26 ur, pri mladih govedih in kravah v laktaciji pa 17,5 ure.
Reduction of post-operative pain after ovariohysterectomy and minor soft tissue surgery: single subcutaneous injection before surgery, for example at the time of induction of anaesthesia.
Zmanjšanje pooperativne bolečine po ovariohisterektomiji in manjših kirurških posegih na mehkih tkivih: enkratna podkožna injekcija pred operacijo, npr.istočasno z indukcijo anestezije.
Musculo-skeletal disorders:
Mišično - skeletna obolenja:
Dogs: IV or SC Cats: SC
Mačke: SC
In animals at anaesthetic risk (e.g. aged animals) intravenous or subcutaneous fluid therapy during anaesthesia should be taken into consideration.
Pri živalih, ki jim anestezija predstavlja življenjski riziko ( npr. starejše živali ), je potrebna intravensko ali podkožno dajanje infuzijskih tekočin.
Any oral follow-up therapy using meloxicam or other Non Steroidal Anti-Inflammatory Drugs (NSAIDs) should not be administered in cats, as appropriate dosage regimens for such follow-up treatments have not been established.
Vsaka nadaljnja oralna terapija, pri kateri se uporabi meloksikam ali drug nesteroidni antiflogistik (NSAID ) pri mačkah ni priporočljiva, ker režim za ustrezno doziranje pri oralni terapiji ni bil določen.
Withdraw the plunger until the black line on the plunger corresponds to your dog's bodyweight in kilograms.
Obrnite stekleničko z merilno brizgo navzdol in povlecite bat brizge do črne črtice, ki ustreza telesni masi v kilogramih vašega psa.
Return the bottle and syringe upright and remove the syringe.
Stekleničko z merilno brizgo ponovno obrnite v pokončen položaj in nežno odstranite merilno brizgo.
2 mg For the full list of excipients, see section 6.1
2 mg Za celoten seznam pomožnih snovi, glejte poglavje 6.1
Ceva Santé Animale - Z.I Très le Bois - 22600 Loudéac - France
Meloxidyl 0.5 mg/ml Ceva Santé Animale - Z.I Tres le Bois - 22600 Loudeac - FRANCE
After two intramuscular doses of 0.4 mg meloxicam/kg, a Cmax value of 1.9 μg/ml was reached after 1 hour in pigs.
Po dveh intramuskularnih odmerkih meloksikama po 0,4 mg/kg je znašala Cmax pri prašičih po 1 uri 1,9 μg/ml.
Shelf life of the veterinary medicinal product as packaged for sale: 3 years.
Rok uporabnosti zdravila v pakiranju za prodajo : 3 leta.
2.0 mg For the full list of excipients, see section 6.1
2.0 mg Za celoten seznam pomožnih snovi, glejte poglavje 6.1
Alleviation of mild to moderate post-operative pain and inflammation following surgical procedures in cats, e.g. orthopaedic and soft tissue surgery.
Lajšanje blage do zmerne postoperativne bolečine in umirjanje vnetja po kirurških posegih pri mačkah, na primer ortopedskih posegih in operacijah mehkega tkiva.
Pregnancy and lactation: See section “Contraindications”
Brejost in laktacija Glej poglavje " Kontraindikacije "
Pre-treatment with anti-inflammatory substances may result in additional or increased adverse effects and accordingly a treatment-free period with such drugs should be observed for at least 24 hours before commencement of treatment.
Predhodno zdravljenje z zdravili s protivnetnim delovanjem lahko povzroči dodatne neželene učinke ali jih okrepi, zato teh zdravil ne smemo dajati najmanj 24 ur pred začetkom zdravljenja.
impaired hepatic, cardiac or renal function and haemorrhagic disorders.
delovanja jeter, srca ali ledvic in pri hemoragičnih obolenjih.
After a single subcutaneous dose of 0.5 mg meloxicam/kg, Cmaxvalues of 2.1 μg/ml and 2.7 μg/ml were reached after 7.7 hours and 4 hours in young cattle and lactating cows, respectively.
Po enkratnem podkožnem odmerku meloksikama po 0,5 mg/kg je znašala Cmax pri mladih govedih 2,1 μg/ml in 2,7 μg/ml po 7,7 ure oziroma 4 urah pri teletih oziroma kravah v laktaciji.
Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, analgesic, anti-exudative and antipyretic effects.
Meloksikam je nesteroidno protivnetno zdravilo (NSAID) iz skupine oksikamov, ki zavira sintezo prostaglandinov in tako deluje protivnetno, analgetično, antieksudativno in antipiretično.
In dogs, these side effects occur generally within the first treatment week and are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal.
Pri psih so našteti neželeni učinki najpogostnejši prvi teden zdravljenja, so večinoma prehodni in po končanem zdravljenju minejo, vendar so lahko v zelo redkih primerih tudi resni ali smrtno nevarni.
Overdose (symptoms, emergengy procedures, antidotes):
Preveliko odmerjanje (simptomi, nujni ukrepi, protistrupi):