natgillin/translations-raw huggingface dataset:
Claxton, L.D., Allen, J., Auletta, A., Mortelmans, K., Nestmann, E. and Zeiger, E., (1987) Guide for the Salmonella typhimurium/Mammalian Microsome Tests for Bacterial Mutagenicity. Mutation Res. 189, p. 83-91.
Claxton, L. D., Allen, J., Auletta, A., Mortelmans, K, Nestmann, E. a Zeiger, E. (1987), Guide for the Salmonella typhimurium/Mammalian Microsome Tests for Bacterial Mutagenicity, Mutation Res., 189, s. 83 – 91.
The temperature in the experimental animal room should be 22 oC (± 3o) for rodents and 18 oC (± 3o) for rabbits.
Teplota v miestnosti pre pokusné zvieratá by mala byť 22 oC (± 3 oC) pre hlodavce a 18 oC (± 3 oC) pre králiky.
If data on spermatogenesis are available from a previous repeated dose study of sufficient duration, e.g. a 90-day study, males of the P generation need not be included in the evaluation.
Ak sú dostupné údaje o spermatogenéze z predchádzajúcej štúdie pri opakovaných dávkach s dostatočným trvaním, napr. 90-dňová štúdia, nie je potrebné do štúdie zahrnúť samce P generácie.
It is recommended, however, that samples or digital recordings of sperm of the P generation are saved, to enable later evaluation.
Odporúča sa však, aby sa uchovali vzorky alebo digitálne záznamy spermy P generácie na umožnenie neskoršieho posúdenia.
Enumeration should be performed on the selected subset of males of all dose groups immediately after killing the animals unless video or digital recordings are made, or unless the specimens are freezed and analysed later.
Počet sa zistí u vybratej podskupiny samcov všetkých dávkových skupín bezprostredne po usmrtení zvierat, pokiaľ sa neurobia video alebo digitálne záznamy, alebo pokiaľ sa vzorky nezamrazia a neanalyzujú neskôr.
ENV/JM/MONO(2001)6, Paris. http://www.olis.oecd.org/olis/2001doc.nsf/LinkTo/env-jm-mono(2001)6.
ENV/JM/MONO(2001)6, Paris. http://www.olis. oecd.org/olis/2001doc.nsf/LinkTo/env-jm-mono(2001)6.
Dilution water
Voda na prípravu roztokov
Deionised or distilled water, free from inhibitory concentrations of toxic substances (e.g. Cu ++ ions) is used.
Používa sa deionizovaná alebo destilovaná voda neobsahujúca inhibičné koncentrácie toxických látok (napr. ióny Cu++).
It must contain no more than 10 % of the organic carbon content introduced by the test material.
Musí obsahovať menej ako 10 % organického uhlíka, ktorý sa nachádza v testovanom materiáli.
The high purity of the test water is necessary to eliminate high blank values.
Vysoká čistota skúšobnej vody je nevyhnutná, aby sa eliminovali vysoké hodnoty slepého pokusu.
The degree of biodegradation is calculated by expressing the concentration of DOC removed (corrected for that in the blank inoculum control) as a percentage of the concentration initially present.
Stupeň biodegradácie sa vypočíta vyjadrením koncentrácie odstráneného DOC (upravené na kontrolu bez inokula) ako percento počiatočnej koncentrácie.
ThODmg O2
/mg ThOD (mg O2
0(Cblo)
(Cblo)
0,05 M borax +0,1 N HCl
0,05 M bórax +0,1 N HCl
Bouche. M. B., 1972, Lombriciens de France, Ecologie et Systematique, Institut National de la Recherche Agronomique, p. 671.
Bouche, M. B., 1972, Lombriciens de France, Ecology et Systématique, Institut National de la Recherche Agronomique, 671 s.
A solution of 5,5-dichlorophenol can for example be prepared by dissolving 0,5 g 3,5-dichlorophenol in 10 ml of 1M NaOH, diluting to approximately 30 ml with distilled water, adding under stirring 0,5M H2SO4 to the point of incipient precipitation — approximately 8 ml of 0,5M H2SO4 will be required — and finally diluting the mixture to one litre with distilled water.
Roztok 5,5-dichlórfenolu môže byť pripravený napríklad rozpustením 0,5 g 3,5-dichlórfenolu v 10 ml 1M NaOH, predtým rozriedeným v približne 30 ml destilovanej vody, pridaním za miešania s 0,5M H2SO4 do bodu počiatočného zrážania – vyžaduje sa približne 8 ml 0,5M H2S04 – a následným zriedením zmesi na jeden liter s destilovanou vodou.
The pH should then be in the range 7 to 8.
Predpokladané pH v pripravenej zmesi sa pohybuje v rozmedzí 7 až 8.
Air
vzduch
Cf and Cw (with standard deviation and range, if appropriate) for all sampling times (Cf expressed in μg/g wet weight (ppm) of whole body or specified tissues thereof e.g. lipid, and Cw in μg/ml (ppm).
Cf a Cw (spolu so štandardnou odchýlkou a rozsahom, ak je to potrebné) v každom čase odberu vzoriek [Cf je vyjadrené v μg/g vlhkej hmotnosti (ppm) celého tela alebo jeho určeného tkaniva, napríklad tuku, a Cw vyjadrené v μg/ml (ppm)].
Cw values for the control series (background should also be reported),
Hodnoty Cw pre kontrolné skupiny (treba uviesť aj hodnoty pozadia),
Bluegill (8)
Pleskáč silný (8)
Clupea harengus
Clupea harensus
P ' % survival observed in the test concentration
P ' % prežívajúcich zistené pri testovanej koncentrácií
C % survival in the control
C prežívajúce pri kontrolnom stanovení
Aquatic Toxicology and Hazard Assessment: Fifth Conference, ASTM STP 766, J.G. Pearson, R.B. Foster and W.E.
Aquatic Toxicology and Hazard Assessment: Fifth Conference, ASTM STP 766, J. G. Pearson, R. B. Foster and W.
silt loam
prachovitá hlina
loam
hlina
loamy sand
hlinitý piesok
clay loam/clay
ílovitá hlina/íl
Russell M.H., (1995), ‘Recommended approaches to assess pesticide mobility in soil’ in Environmental Behavior of Agrochemicals (ed. T.R.
Russell M. H., (1995), „Recommended approaches to assess pesticide mobility in soil“ in Environmental Behavior of Agrochemicals (ed.
Briggs G.G. (1969) ‘Molecular structure of herbicides and their sorption by soils’.
Briggs G. G. (1969), „Molecular structure of herbicides and their sorption by soils“.
These particles, with a size less than 0,2 μm, can have an important impact on the whole adsorption mechanism of a substance in a soil suspension.
Tieto častice, s veľkosťou menšou ako 0,2 μm môžu mať významný vplyv na celý mechanizmus adsorpcie látky v pôdnej suspenzii.
When centrifugation is performed as described above, colloids remain in the aqueous phase and are subjected to analysis together with the aqueous phase.
Po ukončení odstreďovania, ako je popísané vyššie, koloidy zostávajú vo vodnej fáze a sú podrobené analýze spolu s vodnom fázou.
The various methods of determining the vapour pressure are compared as to application, repeatability, reproducibility, measuring range, existing standard.
Rôzne metódy na stanovenie tlaku pary sa porovnávajú z hľadiska ich použiteľnosti, opakovateľnosti, reprodukovateľnosti, rozsahu merania a existujúcich technických noriem.
This is done in the following table.
Prehľadná forma porovnania týchto metód je uvedená v tejto tabuľke.
Mp < 2000
Mp < 2000
However, if further confirmation of the classification is required, an optional supplementary procedure may be conducted, as follows.
Ak sa však vyžaduje ďalšie potvrdenie klasifikácie, môže sa vykonať tento voliteľný doplnkový postup.
Genotoxic Effects of Airborne Agents.
Genotoxic Effects of Airborne Agents. New York, Plenum, pp.
Male Chinese hamsters and mice are commonly used.
Najbežnejšie sa používajú samce čínskych morčiat a myší.
However, males of other appropriate mammalian species may be used.
Použiť sa dajú samce iného vhodného druhu cicavcov.
Norfloxacin
norfloxacín
For each series of tests use only one batch of water, checked beforehand by DOC analysis. Such a check is not necessary for the closed bottle test, but the oxygen consumption of the water must be low.
Pre každú sériu testov použite len úplne totožnú vodu z jednej sady, ktorá je skontrolovaná analýzou DOC. Takáto kontrola nie je nutná pri teste uzavretej fľaše, ale spotreba kyslíka vo vode musí byť nízka.
Disodium monohydrogen orthophosphate dihydrate Na2HPO4.
Hydrogénfosforečnan disodný dihydrát Na2HPO4.
Magnesium sulphate heptahydrate, MgSO4.
Síran horečnatý heptahydrát, MgSO4.
Test (mg)
teste (mg)
Add poorly soluble test chemicals directly on a weight or volume basis or handle as described in Appendix 3, except that neither solvents nor emulsifying agents should be used.
Slabo rozpustné testované chemické látky pridajte priamo, a to podľa ich hmotnosti alebo objemu, alebo s nimi zaobchádzajte podľa toho, ako je to uvedené v dodatku 3, okrem toho by sa nemali pridať rozpúšťadlá ani emulzifikátory.
Add the CO2 absorbent to all flasks in the special cups provided.
Pridajte absorbent CO2 do všetkých príslušných nádob.
2 HNO2 + O2 = 2 HNO3
2 HNO4 + O4 = 2 HNO2
2 NH4Cl + 4 O2 = 2 HNO3 + 2 HCl + 2 H2O
2 NH2Cl + 4 O2 = 2 HNO3 + 2 HCl + 2 H4O
Research Triangle Park, N.C.
Analysis of Human or Animal Adipose Tissue, in Analysis of Pesticide Residues in Human and Environmental Samples, Thompson J. F. (ed.)
Accumulation in Aquatic organisms.
(1985), Accumulation in Aquatic Organisms.
log e w1
log e W1
log e w2
log e W2
logR=-logKd
ads eq
Kd*(msoi/V0) > 0.1 (direct method : measurement of both phases) as appropriate
Rad 2
The temperature of the test media should be within the range 18-22 oC. However, for any one test, the temperature should not, if possible, vary by more than 2 oC within these limits (e.g. 18-20, 19-21 or 20-22 oC).
Teplota testovaného média je v rozmedzí 18 – 22 oC, na žiaden test, ak je to možné, by sa však teplota nemala meniť viac ako o 2 oC v rámci týchto limitov (napr. 18 – 20 oC, 19 – 21 oC, 20 – 22 oC).
This alters the equilibrium of the fluid in the U-tube. To compensate for this, nitrogen or air is admitted to the apparatus via a valve until the pressure indicator fluid is at zero again.
Toto zmení rovnováhu kvapaliny v trubici tvaru U. Na kompenzovanie tohto javu sa do prístroja cez ventil vpúšťa dusík alebo vzduch dovtedy, kým sa kvapalina na indikáciu tlaku opäť neustáli na nulovej hodnote.
In the case of solids, depending on the pressure and temperature range, the manometer liquids listed in 1.6.2.1 are used. The degassed manometer liquid is filled into a bulge on the long arm of the isoteniscope.
V prípade tuhých látok sa použijú tlakomerové kvapaliny uvedené v odseku 1.6.2.1 v závislosti od tlakového a teplotného rozmedzia.
The HPLC method enables partition coefficients to be estimated in the log Pow range 0 to 6. Normally, the partition coefficient of a compound can be estimated to within ± l log unit of the shake-flask value.
Metóda vysokoúčinnej kvapalinovej chromatografie umožňuje odhadovanie rozdeľovacích koeficientov v rozmedzí log Pow od 0 do 6.
Moribund status: being in a state of dying or inability to survive, even if treated.
Moribundný stav: stav umierania alebo neschopnosti prežiť, dokonca aj pri liečbe.
Predictable death: presence of clinical signs indicative of death at a known time in the future before the planned end of the experiment, for example: inability to reach water or food.
Predvídateľná smrť: prítomnosť klinických príznakov charakteristických pre smrť v známom čase v budúcnosti pred plánovaným ukončením experimentu, napríklad neschopnosť prijímať vodu alebo jedlo.
Aeschacher, H.U., Wolleb, U. and Porchet, L., (1987) Liquid Preincubation Mutagenicity Test for Foods. J. Food Safety, 8, p. 167-177.
Aeschacher, H. U, Wolleb, U. a Porchet, L. (1987), Liquid Mutagenicity Test for Foods, J. Food Safety, 8, s. 167 – 177.
Mahon, G.A.T., Green, M.H.L., Middleton, B., Mitchell, I., Robinson, W.D. and Tweats, D.J., (1989) Analysis of Data from Microbial Colony Assays. In: UKEMS Sub-Committee on Guidelines for Mutagenicity Testing.
Mahon, G A. T., Green, M. H. L., Middleton, B., Mitchel, I., Robinson, W.
Selection of species The rat or mouse are the preferred species.
Výber druhov Preferované druhy sú myš a potkan.
The amount of 3H-TdR incorporation in the nuclei and the cytoplasm of morphologically normal cells, as evidenced by the deposition of silver grains, should be determined by suitable methods. Grain counts are determined over the nuclei (nuclear grains, NG) and nucleus equivalent areas over the cytoplasm (cytoplasmic grains, CG).
Počty vlákien sa nehodnotia na S-fázové jadrá, avšak je možné zaznamenať podiel S-fázových buniek.
CG counts are measured by either taking the most heavily labelled area of cytoplasm, or by taking an average of two to three random cytoplasmic grain counts adjacent to the nucleus. Other counting methods (e.g. whole cell counting) may be used if they can be justified (6).
Množstvo aplikovaného 3H-TdR do jadra a cytoplazmy morfologicky normálnych buniek podľa rozloženia striebristých vlákien sa stanovuje vhodnou metódou.
PART VII.
ČASŤ VII.
M.I.T.I.
TEST M.I.T.I.
EC50: is the concentration estimated to immobilise 50 % of the daphnids within a stated exposure period. If another definition is used, this must be reported, together with its reference.
EC50: je koncentrácia odhadnutá na imobilizovanie 50 % dafnií počas stanovenej expozičnej doby; ak sa použije iná definícia, musí sa to zaznamenať spolu s príslušným odkazom.
Cs(t)
Ca(t)
0,1 N NaOH + 50 ml. biphthalate to 100 ml 4,8
17,70 ml 0,1 N NaOH + 50 ml hydrogénftalánu do 100 ml
0,1 N NaOH + 50 ml. biphthalate to 100 ml 5,6
39,85 ml 0,1 N NaOH + 50 ml hydrogénftalánu do 100 ml
0,1 N NaOH + 50 ml. biphthalate to 100 ml 5,8
43,00 ml 0,1 N NaOH + 50 ml hydrogénftalánu do 100 ml
0,1 M monopotassium citrate and 0,1 N HCl at 18 oC [2]49,7 ml.
10,0 B. KOLTHOFF A VLEESCHHOUWER: Citranové tlmivé roztoky KOLTHOFF a VLEESCHHOUWER [2] Zloženie pH
DOC [1]mg/l
DOC [1](mg/liter)
If the sludge cannot be used on the day of collection, 50 ml of synthetic sewage is added to each litre of the activated sludge prepared as described above; this is then aerated overnight at 20 ± 2 oC. It is then kept aerated for use during the day.
Ak kal nie je možné spracovať v deň odberu vzorky, pridá sa 50 ml syntetického kalu na každý liter aktivovaného kalu pripraveného podľa predchádzajúcich doporučení, a takto spracovaná zmes je potom prevzdušňovaná cez noc pri teplote 20 ± 2 oC a následne aj počas celého dňa pred použitím.
Dda
(Dds)
Various estuarine and marine species have been used in different countries, for example: Spot
V jednotlivých krajinách sa používajú rozličné brakické a morské druhy rýb, napríklad:
SCOPE, 1985, John Wiley & Sons Ltd. N.Y.
John Wiley and Sons Ltd, N. Y.
The average r3 for each test concentration may then be compared with the average r3 for the controls. The LOEC can then be identified as before.
Priemerná hodnota r3 na každú testovanú koncentráciu sa môže potom porovnávať s priemernou hodnotou r3 na kontrolné nádrže a LOEC sa môže identifikovať rovnako ako v predchádzajúcom prípade.
var.
rôzne
Fenthion
fention
Triapenthenol
triapentenol
100 kPa 1 bar = 0,1 MPa
1 bar = 0,1 MPa
20 Pa s
22 Pa s
Reischauer pycnometer (for liquids with a kinematic viscosity of less than 100.
Reischauer pycnometer (for liquids with a kinematic viscosity of less than 100 .
Perform validated and accepted in vitro or ex vivo test for skin corrosion Corrosive response Assume corrosivity in vivo. No further testing is needed. ↓ Substance is not corrosive ↓ 6
Obrázok
Mavournin, K.H., Blakey, D.H., Cimino, M.C., Salamone, M.F. and Heddle, J.A., (1990) The In Vivo Micronucleus Assay in Mammalian Bone Marrow and Peripheral Blood. A report of the U.S.
Mavournin, K. H., Blakey, D. H, Cimino, M. C, Salamone, M. F. a Heddle, J. A. (1990), The In vivo Micronucleus Assay in Mammalian Bone Marrow and Peripheral Blood.
Wise, D.L. et al. (1997) Terminology of Developmental Abnormalities in Common Laboratory Mammals (Version 1) Teratology, 55, p. 249-292.
Wise, D.L. et al. (1997) Terminology of Developmental Abnormalities in Common Laboratory Mammals (Version 1) Teratology 55; 249 – 292.
Normally 100 cells are scored from each animal from at least two slides; the scoring of less than 100 cells/animal should be justified. Grain counts are not scored for S-phase nuclei, but the proportion of S-phase cells may be recorded.
Z každého zvieraťa sa z minimálne dvoch sklíčok hodnotí 100 buniek; hodnotenie menej ako 100 buniek/zviera sa zdôvodní.
% DOC removed: a1 -b-c
% odstráneného = a-b-c
For example, in general chemicals with Kd ≤ 1 cm3 g-1 are considered to be qualitatively mobile. Similarly, a mobility classification scheme based on Koc values has been developed by MacCall et al.
Napríklad vo všeobecnosti chemikálie s Kd ≤ 1 cm3 g-1 sú hodnotené ako kvalitatívne mobilné.
log Kom = (4,040 +/- 0,038) - (0,557 +/- 0,012) log Sw Chiou et al.
log Kom = (4,040 +/– 0,038) – (0,557 +/– 0,012) log Sw
Ambrose, D.; Lawrenson, I.J.; Sprake, C.H.S. J. Chem.
Ambrose, D., Lawrenson, I. J., Sprake, C.H.S.
Comsa, J.K. Fremerey and B. Lindenau.
Comsa, J. K. Fremerey and B. Lindenau.
Hansch and A.J. Leo, Substituent Constants for Correlation Analysis in Chemistry and Biology, John Wiley, New York, 1979.
Hansch and A. J. Leo, Substituent Constants for Correlation Analysis in Chemistry and Biology, John Wiley, New York 1979.
Leo, C. Hansch and D. Elkins, Partition coefficients and their uses. Chem.
Leo, C. Hansch and D. Elkins, Partition coefficients and their uses.
Nirrlees, S.J. Noulton, C.T. Murphy, P.J. Taylor; J. Med.
Nirrlees, S. J. Noulton, C. T. Murphy, P. J., Taylor, J. Med.
Ishidate, M. Jr. and Sofuni, T., (1985). The In Vitro Chromosomal Aberration Test Using Chinese Hamster Lung (CHL) Fibroblast Cells in Culture. In: Progress in Mutation Research, Vol. 5, Ashby, J. et al., (Eds) Elsevier Science Publishers, Amsterdam-New York-Oxford, p. 427-432.
Ishidate, M. Jr. a Sofumi, T. (1985), The In Vitro Chromosomal Aberration Test Using Chinese Hamster Lung (CHL) Fibroblast Cells in Culture, in: Progress in Mutation Research, vol. 5, Ashby, J. et al. (eds), Elsevier Science Publishers, Amsterdam – New York – Oxford, s. 427 – 432.
A report from ICPEMC Task Group 9. Mutation Res, 257, p. 147-204.
A report from ICPEMC Task Group 9, Mutation Res., 257, s. 147 – 204.
Toxicol., 14, p. 513-522.
Toxicol 14, s. 513 – 522.
Hayashi, M., Tice, R.R., MacGregor, J.T., Anderson, D., Blackey, D.H., Kirsch-Volders, M., Oleson, Jr. F. B., Pacchierotti, F., Romagna, F., Shimada, H., Sutou, S. and Vannier, B., (1994) In Vivo Rodent Erythrocyte Micronucleus Assay. Mutation Res., 312, p. 293-304.
Hayashi, M., Tice, R. R, MacGregor, J. T., Anderson, D., Blackey, D. H, Kirsch-Volders, M., Oleson, Jr., F. B., Pacchicrotti, F., Romagna, F., Shimada, H., Soutou, S. a Vannier, B. (1994), In vivo Rodent Erythrocyte Micronucleus Assay, Mutation Res., 312, s. 293 – 304.
Treatment of S. cerevisiae strains is usually performed in a liquid test procedure involving either stationary or growing cells. Initial experiments should be done on growing cells.
Ovplyvňovanie S. cerevisiae sa bežne robí v tekutom prostredí použitím stacionárnych alebo rastúcich buniek.
UKEMS Subcommittee on Guidelines for Mutagenicity Testing.
UKEMS Subcommittee on Guidelines for Mutagenicity Testing. Report.
KCl dil. to 100 ml
5,3 ml HCl + 25 ml KCl zriediť na 100 ml
Leiostomus xanthurus
Lelostormus xanthous
Entomol.
Econ.
Weissberger ed.: Technique of Organic Chemistry, Physical Methods of Organic Chemistry, 3rd ed. Chapter IX, Interscience Publ., New York, 1959, vol. I, Part I.
Weissberger ed.: Technique of Organic Chemistry, Physical Methods of Organic Chemistry, 3rd ed., Chapter IX, Interscience Publ., New York, 1959, Vol. I, Part I.
Pin Ring
Krúžok
Chan P.K. and A.W. Hayes.
Chan P.K. and A.W.
Category 5 > 2000 - 5000 ∞
Kategória 5 > 2000 – 5000
Statistical methods may be used as an aid in evaluating the test results (6). Statistical significance should not be the only determining factor for a positive response.
Ako pomôcka sa pri hodnotení výsledkov testov používajú štatistické metódy (6).
Fielder, R.J., Allen, J.A., Boobis, A.R., Botham, P.A., Doe, J., Esdaile, D.J., Gatehouse, D.G., Hodson-Walker, G., Morton, D.B., Kirkland, D.J. and Richold, M. (1992). Report of British Toxicology Society/UK Environmental Mutagen Society Working Group: Dose setting in In vivo Mutagenicity Assays. Mutagenesis, 7, p. 313-319.
Fielder, R I, Allen, J. A., Boobis, A. R, Botham, P. A., Doe, I, Esdaile, D. J., Gatehouse, D. G., Hodson-Walker, G., Morton, D. B., Kirkland, D. J. a Richold, M. (1992), Report of British Toxicology Society/UK Environmental Mutagen Society Working Group: Dose Setting in In vivo Mutagenicity Assays, Mutagenesis, 7, s. 313 – 319.
Locke-Huhle, C., (1983) Endoreduplication in Chinese hamster cells during alpha-radiation induced G2 arrest. Mutation Res. 119, p. 403-413.
Locke-Huhle, C. (1983), Endoreduplication in Chinese Hamster Cells during Alpha Radiation Induced G2 Arrest, Mutation Res., 119, s. 403 – 413.
Statistical methods may be used as an aid in evaluating the test results (18)(19). Statistical significance should not be the only determining factor for a positive response.
Ako pomôcka sa pri hodnotení výsledkov testov používajú štatistické metódy (18) (19).
(1983). The Induction of Micronuclei as a Measure of Genotoxicity. Mutation Res., 123, p. 61-118.
(1983), The Induction of Micronuclei as a Measure of Genotoxicity, Mutation Res., 123, s. 61 – 118.
Romagna, F. and Staniforth, C.D., (1989) The automated bone marrow micronucleus test. Mutation Res., 213, p. 91-104.
Romagna, F. a Staniforth, C. D. (1989), The Automated Bone Marrow Micronucleus Test, Mutation Res., 213, s. 91 – 104.
Matsushima, T., Sawamura, M., Hara, K. and Sugimura, T., (1976) A Safe Substitute for Polychlorinated Biphenyls as an Inducer or Metabolic Activation Systems. In: ‘In vitro metabolic Activation in Mutagenesis Testing’ Eds. F.J. de Serres et al.
Matsushima, T., Sawamura, M., Hara, K. a Sugimura, T. (1976), A Safe Substitute for Polychlorinated Biphenyl as an Inducer of Metabolic Activation Systems, in: In Vitro Metabolic Activation in Mutagenesis testing, de Serres a kol.
Part II. Statistical Evaluation of Mutagenicity Test Data. Ed.
a Tweats, D. J. (1989), Analysis of Data from Microbial Colony Assays, in: UKEMS Sub-Committee on Guidelines for Mutagenicity Testing, Report, Part II, Statistical Evaluation of Mutagenicity test Data, ed.
However, data on the adsorption on the surface of the test vessels gained from this experiment cannot be directly extrapolated to soil/solution experiment. The presence of soil will affect this adsorption.
Údaje o adsorpcii na povrchu testovacích nádob získaných z tohto pokusu nemôžu byť priamo extrapolované na pokus pôdy a roztoku.
Tier 2
Kd*(mpôda l/V0) > 0,3(nepriama metóda, meranie ochudobnenia roztoku)
Tier 3
Rad 1
Software (Program CLOGP-3).
Chem. Software (Program CLOGP-3).
In practice this can be achieved by preparing a 1:1 mixture of the liquid to be tested and cellulose in a greater amount than needed for the trial and transferring 5 ±0,1 g to the pressure vessel. The mixture is to be freshly prepared for each trial.
V praxi sa to dá dosiahnuť prípravou zmesi testovanej kvapaliny s celulózou v pomere 1:1 vo väčšom množstve, ako je potrebné pre test, a do tlakovej nádoby sa nadávkuje 5 g ±0,1 g. Pre každý test osobitne sa pripraví čerstvá zmes.
MacGregor, J.T., Wehr, C.M., Henika, P.R., and Shelby, M.E., (1990) The in vivo Erythrocyte Micronucleus Test: Measurement at Steady State Increases Assay Efficiency and Permits Integration with Toxicity Studies. Fund.
MacGregor, J. T., Wehr, C. M., Henika, P. R a Shelby, M. E. (1990), The in vivo Erythrocyte Micronucleus Test: Measurement at Steady State Increases Assay Efficiency and Permits Integration with Toxicity Studies, Fund.
Mutation Res., 189, p. 123-133.
Mutation Res., 189, 123 – 133.
0Cb(o)
0Cb(l)
the soil/solution ratio, the equilibrium time for adsorption and the amount of test substance adsorbed at equilibrium,
čas potrebný na dosiahnutie adsorpčnej rovnováhy a množstvo testovanej látky adsorbovanej v rovnovážnom stave,
conversion from diet/drinking water test substance concentration (ppm) to the actual dose (mg/kg body weight/day), if applicable, details of food and water quality,
konverzia z koncentrácie testovacej látky v strave/vode (ppm) na samotnú dávku (mg/kg/telesná hmotnosť/deň), ak je to vhodné,
Dose: is the amount of test substance consumed. Dose is expressed as mass (μg) of test substance per test animal (μg/bee).
Dávka: je množstvo skonzumovanej testovanej látky a je vyjadrená ako hmotnosť (ug) testovanej látky na testovaného živočícha (μg/včelu).
Harkins, W.D., Jordan, H.F., J. Amer. Chem.
Harkins, W.
Leo, C. Hansch and D. Elkins, Chem. Rev., 1971, vol. 71, p. 525.
Leo, C. Hansch and D. Elkins, Chem. Rev., 1971, vol. 71, 525.
Leo, C. Hansch, D. Elkins, Chem. Rev., 1971, vol. 71, p. 525.
Leo, C. Hansch, D. Elkins, Chem. Rev., 1971, vol. 71, 525.