Rare (in more than 1 in 10,000 patients but less than 1 in 1000 patients) • high pressure within the eyes, inflammation of the colored part of the eye, extensive inflammation of the eye; • skin cancer, cancer, cancer that affects the lymph system, malignant melanoma; • thyroid disorders; • protein in urine; •. reduction in blood platelets which increases risk of bleeding or bruising, reduction in blood cells which can cause weakness, bruising or make infections more likely; • chest pain, heart stops pumping, blockages in the arteries of the heart, fluid around the heart that can cause severe chest pain, heart problems that can cause shortness of breath or ankle swelling, sensation of heart beating rapidly; • hearing loss, buzzing; • inflammation of the pancreas which causes severe pain in the abdomen and back, inflammation that causes abdominal pain and diarrhoea, blockages of the intestine that cause nausea and vomiting, inflammation that causes pain on swallowing, indigestion, inflammation of the stomach which causes pain in the abdomen, nausea and vomiting; • extensive injury to the liver, abdominal symptoms (such as vomiting, indigestion, constipation), excess fat in the liver which can cause abdominal discomfort, fatigue and feeling unwell, stones in the gallbladder that can cause severe pain and fever, blood test shows changes in the way the liver is working; • inflammation that causes fever, skin rash, joint pain; • inflammation of the large intestine that causes fever, abdominal pain and cramping, constipation; • skin and deep tissue destruction caused by infection; • high blood level of calcium that is usually without symptoms but could cause abdominal pain, depression, weakness and kidney stones, low blood calcium that can cause tingling in the fingers and toes and muscle cramping; • abnormal muscle breakdown which can lead to kidney problems; • swelling in the back of the throat, fluid around the lungs that may cause shortness of breath, pain upon taking a deep breath; • inflammation of abdominal fat causing painful skin nodules; • a sac in the wall of a major artery, blockage of a heart valve usually without symptoms but may cause shortness of breath with exercise, chest pain and fainting, inflammation and clot of a vein, blockage of a blood vessel, sensation of heart beating rapidly; • multiple sclerosis, facial muscle weakness or paralysis.
Rare (la mai mult de 1 pacient din 10000 dar la mai puţin de 1 pacient din 1000): tensiune crescută intraoculară, inflamaţia zonei colorate a ochiului, inflamaţia întregului ochi; • cancer de piele, cancer, cancer care afectează sistemul imunitar, melanoma malign; • tulburări ale tiroidei; • proteinurie; • scăderea numărului de trombocite care creşte riscul sângerărilor sau a apariţiei vânătăilor, • scăderea numărului celulelor sanguine care pot cauza slăbiciune, vânătăi sau pot determina apariţia infecţiilor mai uşor; dureri în piept, oprirea pompării sângelui de către inimă, obstrucţii ale arterelor inimii, lichid în • jurul inimii care produce dureri puternice de piept, probleme cardiace care pot duce la scurtarea respiraţiei sau edeme ale gleznelor, senzaţia de bătăi cardiace rapide; pierderea auzului, ţiuituri; • inflamaţii ale pancreasului care determină dureri puternice în abdomen şi spate, inflamaţie care • determină dureri abdominale sau diaree, obstrucţii intestinale care produc greaţă şi vărsături, inlamaţii care produc durere la înghiţire, indigestie, inflamaţia stomacului care produce dureri abdominale, greaţă şi vărsături; afectarea extinsă a ficatului, simptome abdominale (cum sunt vărsături, indigestie, constipaţie), • încărcare cu grăsime a ficatului care produce discomfort abdominal, oboseală şi senzaţie de rău, pietre la vezica biliară care produc dureri puternice şi febră, teste de laborator care arată modificări ale funcţiei ficatului; inflamaţii care produc febră, erupţii pe piele, dureri articulare; • inflamaţii ale intestinului gros care produc febră, dureri abdominale şi crampe, constipaţie; • leziuni ale pielii şi ale ţesuturilor profunde determinate de infecţii; • valori crescute ale calciului din sânge care de obicei nu sunt simptomatice dar pot determina • dureri abdominale, depresie, slăbiciune, pietre la rinichi, valori scăzute ale calciului din sânge care determină furnicături ale degetelor de la mâini şi picioare şi crampe musculare; oboseală musculară anormală care poate duce la probleme renale; •