natgillin/translations-raw huggingface dataset:
The median PFS times were 4.2 months (95% CI: 2.8, 5.7) for pemetrexed (HR=0.59; p-value=0.0004 for crizotinib compared with pemetrexed) and 2.6 months (95% CI: 1.6, 4.0) for docetaxel (HR=0.30; p-value &lt; 0.0001 for crizotinib compared with docetaxel).
Medijan vremena PFS-a bio je 4,2 mjeseca (95% CI: 2,8; 5,7) za pemetreksed (HR=0,59; p-vrijednost=0,0004 za krizotinib u usporedbi s pemetreksedom) i 2,6 mjeseca (95% CI: 1,6; 4,0) za docetaksel (HR=0,30; p- vrijednost &lt; 0,0001 za krizotinib u usporedbi s docetakselom). b.
The median radiographic progression-free survival was 5.6 months for patients treated with ZYTIGA and 3.6 months for patients who received placebo (HR = 0.673; 95% CI: [0.585; 0.776], p &lt; 0.0001).
Medijan preživljenja bez radiološki dokazane progresije bolesti iznosilo je 5,6 mjeseci u bolesnika liječenih lijekom ZYTIGA te 3,6 mjeseci u bolesnika koji su primali placebo (HR=0,673; 95% CI: [0,585; 0,776], p &lt; 0,0001).
The median survival of all patients enrolled was 17 months (range &lt; 1 to 36+ months).
Medijan preživljenja svih uključenih bolesnika bio je 17 mjeseci (raspon &lt; 1 do 36+ mjeseci).
The median time from aHUS diagnosis to first dose of Soliris was 14 months (range &lt; 1, 110 months).
Medijan vremena od dijagnoze aHUS-a do prve doze lijeka Soliris iznosio je 14 mjeseci (raspon &lt; 1, 110 mjeseci).
The median time from current thrombotic microangiopathy manifestation to first dose of Soliris was 1 month (range &lt; 1 to 16 months).
Medijan vremena od postojeće manifestacije trombotične mikroangiopatije do prve doze lijeka Soliris iznosio je jedan mjesec (raspon, &lt; 1 do 16 mjeseci).
The median time to first skeletal-related event was 16.7 months for patients treated with enzalutamide and 13.3 months for patients who received placebo (HR = 0.688, 95% CI: [0.566, 0.835]; p &lt; 0.0001).
Medijan vremena do prvog koštanog događaja iznosio je 16,7 mjeseci u bolesnika liječenih enzalutamidom i 13,3 mjeseca u bolesnika koji su primali placebo (omjer hazarda = 0,688, 95% CI: [0,566, 0,835]; p &lt; 0,0001).
The median time to initiation of cytotoxic chemotherapy was 28.0 months for patients receiving enzalutamide and 10.8 months for patients receiving placebo (HR = 0.350, 95% CI: [0.303, 0.403], p &lt; 0.0001).
Medijan vremena do započinjanja citotoksične kemoterapije iznosio je 28,0 mjeseci u bolesnika koji, su primali enzalutamid i 10,8 mjeseci u bolesnika koji su primali placebo (HR = 0,350, 95% CI: [0,303 0,403], p &lt; 0,0001).
The median time to PS ≥ 2 for the Lonsurf group and placebo group was 5.7 months and 4.0 months, respectively, with a hazard ratio of 0.66 (95% CI: [0.56, 0.78]), p &lt; 0.0001.
Medijan vremena do PS ≥ 2 u skupini liječenoj Lonsurfom bio je 5,7 mjeseci, a u placebo skupini 4,0 mjeseci s omjerom hazarda 0,66 (95% CI [0,56; 0,78]), p &lt; 0,0001.
The median time to PSA progression per PCWG2 criteria was 11.2 months for patients treated with enzalutamide and 2.8 months for patients who received placebo [HR = 0.169, (95% CI: 0.147, 0.195), p &lt; 0.0001].
Medijan vremena do progresije PSA prema kriterijima PCWG2 iznosio je 11,2 mjeseci u bolesnika liječenih enzalutamidom i 2,8 mjeseci u bolesnika koji su primali placebo [HR = 0,169, (95% CI: 0,147; 0,195), p &lt; 0,0001].
The median time to testosterone &gt; 1.5 ng/mL (above lower limit of normal range) was 168 days.
Medijan vremena do razine testosterona &gt; 1,5 ng/ml (iznad donje granice normalnog raspona) iznosio je 168 dana.
The median time to viral suppression was shorter with ABC/3TC + DTG (28 vs 84 days, p &lt; 0.0001).
Medijan vremena do virusne supresije bio je kraći u skupini koja je primala ABC/3TC + DTG (28 naspram 84 dana, p &lt; 0,0001).
The median times for the most relevant boceprevir-resistant variants observed in genotype 1b patients ( &gt; 10%) to become undetectable were as follows: I/V170A, 0.46 years; T54A, 0.47 years; V55A, years; A156S, 0.89 years; and T54S, 1.11 years.
Medijani vremena potrebnog da najznačajnije varijante rezistentne na boceprevir primijećene u bolesnika s genotipom 1b ( &gt; 10%) postanu nemjerljive bili su sljedeći: 0,46 godina za I/V170A; 0,47 godina za T54A; 0,83 godina za V55A; 0,89 godina za A156S; 1,11 godina za T54S.
The median times to progression in these endpoints ranged from 0.7 to 2.1 months longer for TMZ than for procarbazine (log rank p = &lt; 0.01 to 0.03).
Medijan vremena do progresije bolesti prema ovim mjerama ishoda bio je za 0,7 do 2,1 mjeseca dulji u skupini koja je primala TMZ nego u skupini koja je primala prokarbazin (log- rang p = &lt; 0,01 do 0,03).
The median times to progression in these endpoints ranged from 0.7 to 2.1 months longer for TMZ than for procarbazine (log rank p = &lt; 0.01 to 0.03).
Medijan vremena do progresije bolesti prema ovim mjerama ishoda bio je za 0,7 do 2,1 mjeseca dulji u skupini koja je primala TMZ nego u skupini koja je primala prokarbazin (log-rang p = &lt; 0,01 do 0,03).
The median times to progression in these endpoints ranged from 0.7 to 2.1 months longer for TMZ than for procarbazine (log rank p= &lt; 0.01 to 0.03).
Medijan vremena do progresije bolesti prema ovim mjerama ishoda bio je za 0,7 do 2,1 mjeseca dulji u skupini koja je primala TMZ nego u skupini koja je primala prokarbazin (log-rang p = &lt; 0,01 do 0,03).
The median trough serum concentrations of ustekinumab in patients with higher weight ( &gt; 100 kg) in the 90 mg group were comparable to those in patients with lower weight (≤ 100 kg) in the 45 mg group.
Medijan najniže serumske koncentracije ustekinumaba kod bolesnika veće tjelesne težine ( &gt; 100 kg) u grupi od 90 mg mogla se usporediti s bolesnicima niže tjelesne težine (≤ 100 kg) u grupi s 45 mg.
The medicinal product is not recommended in obese children and adolescents with body mass index Weight (kg)/ (m2) &gt; 30 kg/m² until further data become available.
Primjena ovog lijeka ne preporučuje se u pretile djece i adolescenata s indeksom tjelesne mase težina (kg)/ (m2) &gt; 30 kg/m² sve dok ne budu dostupni dodatni podaci.
The medicinal product is not recommended in obese children and adolescents with body mass index Weight (kg)/(m²) &gt; 30 kg/m² until further data become available.
Primjena lijeka ne preporučuje se u pretile djece i adolescenata s indeksom tjelesne mase težina (kg)/ (m²) &gt; 30 kg/m² sve dok ne budu dostupni dodatni podaci.
The metabolites hydroxy-dalbavancin and mannosyl aglycone have been detected in urine ( &lt; 25 % of administered dose).
Metaboliti hidroksidalbavancin i manozil aglikon otkriveni su u mokraći ( &lt; 25 % od primijenjene doze).
The minimum inhibitory concentrations of itraconazole for different Aspergillus isolates in birds in Europe varies between 0.25 and &gt; 16 g/ml.
Minimalne inhibitorne koncentracije itrakonazola za različite izolate Aspergillus u ptica u Europi variraju između 0,25 i &gt; 16 g/ml.
The MMR rate at 12 months was statistically significantly higher for nilotinib 300 mg twice daily compared to imatinib 400 mg once daily (44.3% versus 22.3%, p &lt; 0.0001).
Stopa MMR-a u 12. mjesecu je bila statistički značajno viša za 300 mg nilotiniba dva puta na dan u usporedbi s 400 mg imatiniba jedanput na dan (44,3% u odnosu na 22,3%, p &lt; 0,0001).
The model-adjusted mean decrease in HbA1c from baseline with Eperzan was -0.80 (n = 125), -0.83 (n = 98), and -1.08 (n = 19) in patients with mild (eGFR 60 to 89 ml/min/1.73m2), moderate (eGFR 30 to 59 ml/min/1.73m2), and severe (eGFR &lt; 30 ml/min/1.73m2) renal impairment, respectively (see Table 9).
Za model prilagođeno srednje smanjenje vrijednosti HbA1c od početne vrijednosti kod primjene lijeka Eperzan iznosilo je -0,80 (n = 125) u bolesnika s blagim oštećenjem (eGFR 60-89 ml/min/1,73 m2), -0,83 (n = 98) u bolesnika s umjerenim oštećenjem (eGFR 30-59 ml/min/1,73 m2), odnosno -1,08 (n = 19) u bolesnika s teškim oštećenjem bubrežne funkcije (eGFR &lt; 30 ml/min/1,73 m2) (vidjeti Tablicu 9).
The modeled treatment effect for the percent change in urine KS, compared to placebo, was -40.7 % (CI95, -49.0, -32.4; p &lt; 0.0001) for the 2 mg/kg per week regimen.
Modelirani učinak liječenja za postotak promjene KS-a u mokraći u usporedbi s placebom bio je -40,7 % (CI95, -49,0, -32,4; p &lt; 0,0001) za režim doze od 2 mg/kg/tjedno.
The modest lowering effects on BP were consistent over time and a similar number of subjects had systolic BP &lt; 130 mmHg or diastolic BP &lt; 80 mmHg at Week 24 across the treatment groups.
Skromni učinci na sniženje krvnog tlaka bili su postojani tijekom vremena, a u svim je liječenim skupinama sličan broj ispitanika imao sistolički krvni tlak &lt; 130 mmHg ili dijastolički krvni tlak &lt; 80 mmHg u 24. tjednu.
The most common adverse drug reactions (ADR) ( &gt; 30%) reported with vemurafenib include arthralgia, fatigue, rash, photosensitivity reaction, nausea, alopecia and pruritus.
Najčešće nuspojave ( &gt; 30%) prijavljene kod liječenja vemurafenibom uključuju artralgiju, umor, osip, fotosenzitivne reakcije, mučninu, alopeciju i pruritus.
The most common adverse reaction ( &gt; 1 %) leading to discontinuation of posaconazole concentrate for solution for infusion 300 mg once daily was AML (1 %).
Najčešća nuspojava ( &gt; 1%) koja je dovela do prekida primjene posakonazol koncentrata za otopinu za infuziju u dozi od 300 mg jedanput na dan bio je AML (1%).
The most common adverse reactions ( &gt; 5%) in controlled periods of the adult psoriasis, psoriatic arthritis and Crohn’s disease clinical studies with ustekinumab were nasopharyngitis and headache.
Najčešće prijavljene nuspojave ( &gt; 5%) u kontroliranim razdobljima kliničkih ispitivanja psorijaze, psorijatičnog artritisa i Crohnove bolesti kod odraslih bolesnika s ustekinumabom bile su nazofaringitis i glavobolja.
The most common adverse reactions ( &gt; 20%) observed with a higher frequency in the placebo plus vemurafenib arm were arthralgia, alopecia, and hyperkeratosis.
Najčešće nuspojave ( &gt; 20%) primijećene s većom učestalošću u skupini koja je primala placebo plus vemurafenib bile su artralgija, alopecija i hiperkeratoza.
The most common adverse reactions ( &gt; 25%) during therapy with lapatinib were gastrointestinal events (such as diarrhoea, nausea, and vomiting) and rash.
Najčešće nuspojave ( &gt; 25%) tijekom liječenja lapatinibom bile su gastrointestinalne nuspojave (primjerice proljev, mučnina i povraćanje) i osip.
The most common adverse reactions ( &gt; 3%) during clinical trials were headache (10.4%), somnolence (8.6%), nausea (4.0%), and dizziness (3.1%).
Najčešće nuspojave ( &gt; 3 %) tijekom kliničkih ispitivanja bile su glavobolja (10,4 %), somnolencija (8,6 %), mučnina (4,0 %) i omaglica (3,1 %).
The most common adverse reactions (occurring in &gt; 10% of patients) with elotuzumab treatment were infusion related reactions, diarrhoea, herpes zoster, nasopharyngitis, cough, pneumonia, upper respiratory tract infection, lymphopenia and weight decreased.
Najčešće nuspojave (koje su se javile u &gt; 10% bolesnika) kod liječenja elotuzumabom bile su reakcije na infuziju, proljev, herpes zoster, nazofaringitis, kašalj, pneumonija, infekcija gornjih dišnih putova, limfopenija i smanjenje tjelesne težine.
The most common adverse reactions (occurring in &gt; 20% of subjects) were: anaemia, fatigue, diarrhoea, thrombocytopenia, nausea, pyrexia, dyspnoea, respiratory tract infection, cough and peripheral oedema.
Najčešće nuspojave (javljaju se u &gt; 20% ispitanika) bile su: anemija, umor, proljev, trombocitopenija, mučnina, pireksija, dispneja, infekcije dišnog sustava, kašalj i periferni edem.
The most common NCI-CTCAE v.3 Grade 3-4 ADRs ( &gt; 10%) were neutropenia, febrile neutropenia and leucopenia, and the most common serious adverse events were febrile neutropenia, neutropenia and diarrhoea.
Najčešće nuspojave stupnja 3-4 prema verziji 3 NCI-CTCAE kriterija bile su neutropenija, febrilna neutropenija i leukopenija, a najčešći ozbiljni štetni događaji bili su febrilna neutropenija, neutropenija i proljev.
the most common serious ADRs ( &gt; 0.5% of patients) were haemorrhage, pyrexia, dyspnoea, musculoskeletal pain, thrombocytopenia, abdominal pain and vomiting. the most common adverse drug reactions (ADRs) (≥25%) with trastuzumab emtansine were nausea, fatigue, and headache.
najčešće ozbiljne nuspojave na lijek ( &gt; 0,5% bolesnika) bile su krvarenje, pireksija, dispneja, bol u mišićno-koštanom sustavu, trombocitopenija, bol u abdomenu i povraćanje. najčešće nuspojave (≥ 25%) trastuzumab emtanzina bile su mučnina, umor i glavobolja.
The most commonly reported ( &gt; 20%) events following dual or triple therapy in both treatment groups (basiliximab vs. placebo) were constipation, urinary tract infection, pain, nausea, peripheral oedema, hypertension, anaemia, headache, hyperkalaemia, hypercholesterolaemia, postoperative wound complication, weight increase, increase in blood creatinine, hypophosphataemia, diarrhoea and upper respiratory tract infection.
Najčešće zabilježeni ( &gt; 20%) štetni događaji nakon dvostruke ili trostruke terapije u obje skupine (basiliksimab naspram placebo) bile su konstipacija, infekcija mokraćnog sustava, bol, mučnina, periferni edemi, hipertenzija, anemija, glavobolja, hiperkalijemija, hiperkolesterolemija, postoperativna komplikacija rane, porast tjelesne težine, povišeni kreatinin u krvi, hipofosfatemija, proljev i infekcija gornjih dišnih putova.
The most commonly reported ( &gt; 20%) events following dual therapy in both ( &lt; 35 kg vs.  35 kg weight) cohorts were urinary tract infection, hypertrichosis, rhinitis, pyrexia, hypertension, upper respiratory tract infection, viral infection, sepsis and constipation.
Najčešće zabilježeni ( &gt; 20%) štetni događaji nakon dvostruke terapije u obje ( &lt; 35 kg naspram ≥35 kg tjelesne težine) kohorte bile su infekcija mokraćnog sustava, hipertrihoza, rinitis, vrućica, hipertenzija, infekcija gornjih dišnih puteva, virusna infekcija, sepsa i konstipacija.
The most commonly reported adverse drug reactions (reported in &gt; 1/10 patients) are reactions consistent with the pharmacologic action of Kepivance on skin and oral epithelium, e.g. oedema, including peripheral oedema, and hypertrophia of oral structures.
Najčešće nuspojave na lijek (u &gt; 1/10 bolesnika) su reakcije koje odgovaraju farmakološkom djelovanju Kepivancea na kožu i oralni epitel, npr. edem, uključujući periferni edem i hipertrofiju oralnih struktura.
The most commonly reported adverse reaction leading to discontinuation in patients treated with Plegridy 125 micrograms subcutaneously every 2 weeks was influenza-like illness ( &lt; 1%).
Najčešće prijavljena nuspojava koja je dovela do prekida liječenja u bolesnika liječenih Plegridyjem u dozi od 125 mikrograma supkutanom injekcijom svaka dva tjedna, je bila bolest nalik gripi ( &lt; 1%).
The most commonly reported adverse reactions (occurring in &gt; 10% of patients) are tremor, renal impairment, hyperglycaemic conditions, diabetes mellitus, hyperkalaemia, infections, hypertension and insomnia.
Najčešće prijavljene nuspojave izazvane lijekom (javljaju se u &gt; 10% bolesnika) uključuju tremor, oštećenje bubrega, hiperglikemička stanja, šećernu bolest, hiperkalijemiju, infekcije, hipertenziju i nesanicu.
The most commonly reported adverse reactions (occurring in &gt; 10% of patients) are tremor, renal impairment, hyperglycaemic conditions, diabetes mellitus, hyperkalaemia, infections, hypertension and insomnia.
Najčešće zabilježene nuspojave (koje nastaju u &gt; 10% bolesnika) su tremor, oštećenje funkcije bubrega, hiperglikemijska stanja, šećerna bolest, hiperkalijemija, infekcije, hipertenzija i nesanica.
The most commonly reported adverse reactions (occurring in &gt; 10% of patients) are thrombocytopaenia, anaemia, pyrexia, hypertension, hypokalaemia, hypophosphataemia, urinary tract infection, hypercholesterolaemia, hyperglycaemia, hypertriglyceridaemia, abdominal pain, lymphocoele, peripheral oedema, arthralgia, acne, diarrhoea, pain, constipation, nausea, headache, increased blood creatinine, and increased blood lactate dehydrogenase (LDH).
Najčešće prijavljene nuspojave (javljaju se u &gt; 10% bolesnika) su trombocitopenija, anemija, pireksija, hipertenzija, hipokalemija, hipofosfatemija, infekcije mokraćnih puteva, hiperkolesterolemija, hiperglikemija, hipertrigliceridemija, bol u abdomenu, limfokela, periferni edem, artralgija, akne, proljev, bol, konstipacija, mučnina, glavobolja, povišena razina kreatinina u krvi, povišena razina laktat dehidrogenaze (LDH) u krvi.
The most commonly reported adverse reactions (occurring in 10% of patients) are thrombocytopaenia, anaemia, pyrexia, hypertension, hypokalaemia, hypophosphataemia, urinary tract infection, hypercholesterolaemia, hyperglycaemia, hypertriglyceridaemia, abdominal pain, lymphocoele, peripheral oedema, arthralgia, acne, diarrhoea, pain, constipation, nausea, headache, increased blood creatinine, and increased blood lactate dehydrogenase (LDH).
Najčešće prijavljene nuspojave (javljaju se u &gt; 10% bolesnika) su trombocitopenija, anemija, pireksija, hipertenzija, hipokalemija, hipofosfatemija, infekcije mokraćnih puteva, hiperkolesterolemija, hiperglikemija, hipertrigliceridemija, bol u abdomenu, limfokela, periferni edem, artralgija, akne, proljev, bol, konstipacija, mučnina, glavobolja, povišena razina kreatinina u krvi, povišena razina laktat dehidrogenaze (LDH) u krvi.
The most commonly reported adverse reactions are upper gastrointestinal adverse reactions including abdominal pain, dyspepsia, oesophageal ulcer, dysphagia, abdominal distension and acid regurgitation ( &gt; 1 %).
Najčešće prijavljene nuspojave su nuspojave u gornjem dijelu gastrointestinalnog trakta koje uključuju bol u abdomenu, dispepsiju, ulkus jednjaka, disfagiju, abdominalnu distenziju i regurgitaciju želučane kiseline ( &gt; 1%).
The most commonly reported adverse reactions for tacrolimus (occurring in &gt; 10% of patients) are tremor, renal impairment, hyperglycaemic conditions, diabetes mellitus, hyperkalaemia, infections, hypertension and insomnia.
Najčešće prijavljene nuspojave na takrolimus (javljaju se u &gt; 10% bolesnika) uključuju tremor, oštećenje bubrega, hiperglikemiiska stanja, šećernu bolest, hiperkalijemiju, infekcije, hipertenziju i nesanicu.
The most commonly reported adverse reactions in surgical patients were cough, airway complication of anaesthesia, anaesthetic complications, procedural hypotension and procedural complication (Common (≥ 1/100 to &lt; 1/10)).
Najčešće prijavljene nuspojave u kirurških bolesnika bile su kašalj, komplikacija anestezije na dišnim putevima, anesteziološke komplikacije, proceduralna hipotenzija i proceduralna komplikacija (često (≥ 1/100 i &lt; 1/10)).
The most commonly reported adverse reactions leading to discontinuation (incidence &gt; 1%) in patients treated with Tecfidera were flushing (3%) and gastrointestinal events (4%).
Najčešće prijavljene nuspojave koje su dovele do prekida (incidencija &gt; 1%) u bolesnika liječenih Tecfiderom su crvenilo uz osjećaj vrućine (3%), i gastrointestinalne smetnje (4%).
The most commonly reported adverse reactions of docetaxel alone are: neutropenia (which was reversible and not cumulative; the median day to nadir was 7 days and the median duration of severe neutropenia ( &lt; 500 cells/mm3) was 7 days), anaemia, alopecia, nausea, vomiting, stomatitis, diarrhoea and asthenia.
Najčešće prijavljene nuspojave samog docetaksela su: neutropenija (koja je bila reverzibilna i nije bila kumulativna; medijan javljanja najnižih vrijednosti je bio 7 dana, a medijan trajanja teške neutropenije (500 stanica/mm3) je bio 7 dana), anemija, alopecija, mučnina, povraćanje, stomatitis, proljev i astenija.
The most commonly reported adverse reactions of docetaxel alone are: neutropenia (which was reversible and not cumulative; the median day to nadir was 7 days and the median duration of severe neutropenia ( &lt; 500 cells/mm3) was 7 days), anaemia, alopecia, nausea, vomiting, stomatitis, diarrhoea and asthenia.
Najčešće prijavljene nuspojave samog docetaksela su: neutropenija (koja je bila reverzibilna i nije bila kumulativna; medijan javljanja najnižih vrijednosti je bio 7 dana, a medijan trajanja teške neutropenije ( &lt; 500 stanica/mm3 ) je bio 7 dana), anemija, alopecija, mučnina, povraćanje, stomatitis, proljev i astenija.
The most commonly reported related adverse reactions (occurring in &gt; 1% of patients) were: fungal infection, insomnia, dysgeusia, headache, dizziness, nausea, constipation, diarrhoea, vomiting, alanine aminotransferase increased, aspartate aminotransferase increased, pruritus, rash, renal failure acute, blood creatinine increased, urine abnormality (foamy urine), fatigue and chills.
Najčešće prijavljene nuspojave (koje su se pojavile na &gt; 1% bolesnika) bile su: gljivična infekcija, nesanica, disgeuzija, glavobolja, omaglica, mučnina, konstipacija, dijareja, povraćanje, povećanje alanin aminotransferaze, povećanje aspartat aminotransferaze, svrbež, osip, akutno zatajenje bubrega, povećanje razine kreatinina u krvi, promjena mokraće (pjenušava mokraća), umor i zimica.
The most frequent adverse drug reactions ( &gt; 10.0% of patients) during treatment with SIRTURO in the controlled trials were nausea (35.3% in the SIRTURO group vs 25.7% in the placebo group), arthralgia (29.4% vs 20.0%), headache (23.5% vs 11.4%), vomiting (20.6% vs 22.9%) and dizziness (12.7% vs 11.4%).
Najčešće nuspojave ( &gt; 10,0% bolesnika) u kontroliranim ispitivanjima tijekom liječenja lijekom SIRTURO bile su mučnina (35,3% u SIRTURO skupini naspram 25,7% u placebo skupini), artralgija (29,4% naspram 20,0%), glavobolja (23,5% naspram 11,4%), povraćanje (20,6% naspram 22,9%) i omaglica (12,7% naspram 11,4%).
The most frequent event was a haematoma &lt; 5 cm at puncture site.
Najučestaliji događaj bio je hematom &lt; 5 cm na mjestu uboda.
The most frequent Grade 3-4 adverse reactions (incidence ≥1/100 to &lt; 1/10) were stomatitis, anaemia, hyperglycaemia, infections, fatigue, diarrhoea, pneumonitis, asthenia, thrombocytopenia, neutropenia, dyspnoea, proteinuria, lymphopenia, haemorrhage, hypophosphataemia, rash, hypertension, pneumonia, alanine aminotransferase (ALT) increased, aspartate aminotransferase (AST) increased and diabetes mellitus.
Najučestalije nuspojave stupnja 3-4 (incidencija ≥1/100 do &lt; 1/10) su bile stomatitis, anemija, hiperglikemija, infekcije, umor, proljev, pneumonitis, astenija, trombocitopenija, neutropenija, dispneja, proteinurija, limfopenija, hemoragija, hipofosfatemija, osip, hipertenzija, pneumonija, povišena alanin aminotransferaza (ALT), povišena aspartat aminotransferaza (AST) i šećerna bolest.
The most frequently ( &gt; 25% of subjects) detected post-baseline RAVs in these subjects were amino acid substitutions V36M (61%) and R155K (68%) in subjects infected with genotype 1a viruses and T54A (42%), T54S (37%), A156S (26%) and V170A (32%) in subjects infected with genotype 1b viruses.
Najčešći RAV-ovi otkriveni u tih ispitanika nakon početka ispitivanja (otkriveni u &gt; 25% ispitanika) bili su V36M (61%) i R155K (68%) u ispitanika zaraženih virusom genotipa 1a, te T54A (42%), T54S (37%), A156S (26%) i V170A (32%) u ispitanika zaraženih virusom genotipa 1b.
The most frequently ( &gt; 5% of adult subjects treated) reported adverse reactions with fosamprenavir/ritonavir combination were gastrointestinal reactions (nausea, diarrhoea, abdominal pain and vomiting) and headache.
Najučestalije ( &gt; 5% liječenih odraslih ispitanika) prijavljene nuspojave s kombinacijom fosamprenavira/ritonavira bile su gastrointestinalne reakcije (mučnina, proljev, bol u abdomenu i povraćanje) i glavobolja.
The most frequently observed adverse drug reactions in patients treated with delamanid (i.e. incidence &gt; 10%) are nausea (38.3%), vomiting (33%), and dizziness (30.2%).
Najčešće uočene nuspojave na lijek u bolesnika liječenih delamanidom (primjerice, incidencija &gt; 10%) su mučnina (38,3%), povraćanje (33%) i omaglica (30,2%).
The most frequently reported adverse reaction ( &gt; 25 %) with an onset during the posaconazole intravenous phase of dosing with 300 mg once daily was diarrhoea (32 %).
Najčešće prijavljena nuspojava ( &gt; 25%) koja je nastupila tijekom intravenske faze primjene doze od 300 mg jedanput na dan bio je proljev (32%).