natgillin/translations-raw huggingface dataset:
at least one 3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol of formula (I), optionally in form of one of its pure stereoisomers, in particular an enantiomer or a diastereomer, a racemate or in form of a mixture of its stereoisomers, in particular enantiomers and/or diastereomers in any mixing ratio, or any corresponding acid addition salt thereof, or any solvate thereof, and 
najmanje jedan 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol formule (I), [image] po mogućnosti u obliku jednog od njegovih čistih stereoizomera, posebno enantiomera ili dijastereoizomera, racemata ili u obliku smjese njegovih stereoizomera, posebno enatniomera i/ili dijastereoizomera u bilo kojem obliku miješanja, ili bilo koje njegove odgovarajuće kiselinske adicijske soli, ili bilo kojeg njegovog solvata, i
Combination according to any of claims 1-4, characterized in that components (a) and (b) are present in such a weight ratio that the composition will exert a synergistic effect upon administration to a patient. 
Kombinacija prema bilo kojem zahtjevu od 1 do 4, naznačena time da su komponente (a) i (b) prisutne u takvom težinskom omjeru da će sastav vršiti sinergistički učinak nakon primjene na pacijentu.
A pharmaceutical salt, characterized in that the cationic salt component is formed from 
Farmaceutska sol, naznačena time da je komponenta kationske soli formirana od
at least one compound 3-(3-Dimethyfamino-1-ethyl-2-methyl-propyl)-phenol of formula (I), optionally in form of one of its pure stereoisomers, in particular an enantiomer or a diastereomer, a racemate or in form of a mixture of its stereoisomers, in particular enantiomers and/or diastereomers in any mixing ratio, or any solvate thereof, and the anionic salt component is formed from 
najmanje jednog 3-(3-dimetilamino-1-etil-2-metil-propil)-fenola formule (I), [image] po mogućnosti u obliku jednog od njegovih čistih stereoizomera, posebno enantiomera ili dijastereoizomera, racemata ili u obliku smjese njegovih stereoizomera, posebno enatniomera i/ili dijastereoizomera u bilo kojem obliku miješanja, ili bilo kojeg njegovog solvata, i da je komponenta anionske soli formirana od
A compound according to claim 15 or 16, characterized in that it is derived from the compound (1R,2R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol of formula (I') 
Spoj prema zahtjevu 15 ili 16, naznačen time da je dobiven od spoja (1R,2R)-3-(3-dimetilamino-1-etil-2-metil-propil)-fenol formule (I’) [image]
A dosage form according to claim 7, characterized in that it is suitable for oral, intravenous, intraperitoneal, intradermal, intrathekal, intramuscular, intranasal, transmucosal, subcutaneous, or rectal administration. 
Oblik doziranja prema zahtjevu 7, naznačen time da je pogodan za oralnu, intravenoznu, intraperitonealnu, intradermalnu, intratekalnu, intramuskularnu, intranazalnu, transmukoznu, potkožnu, ili rektalnu primjenu.
Use according to claim 24 or 25, characterised in that the medicament is adapted for simultaneous or sequential administration, wherein compound (a) may be administered before or after compound (b) and wherein compounds (a) or (b) are administered either by the same or a different pathway of administration. 
Upotreba prema zahtjevu 24 ili 25, naznačena time da je lijek prilagođen za istodobnu ili sekvencijalnu primjenu, gdje se spoj (a) može primijeniti prije ili nakon spoja (b) i gdje su spojevi (a) ili (b) primijenjeni ili istim ili različitim putem primjene.
Process according to any of the previous claims, wherein the transport of sulphuric acid across said membrane is effected by passing a receiving liquid (preferably water) on the filtrate side of the membrane. 
Postupak prema bilo kojem prethodnom zahtjevu, naznačen time, da je transport sumporne kiseline preko spomenute membrane pospješen prolaskom prijamne tekućine na filtratnoj strani membrane, a ta prijamna tekućina je najbolje voda.
W is selected from the group consisting of oxygen, -S(O)n- and -NR9- where n is zero, one or two, R9 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, acyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic and R8 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic, or when W is -NR9- then R8 and R9, together with the nitrogen atom to which they are bound, can be joined to form a heterocyclic or a substituted heterocyclic group, provided that when W is -S(O)n- and n is one or two, then R8 is not hydrogen; 
W je odabran iz skupine koja sadrži kisik, -S(O)n- i -NR9- gdje n je nula, jedan ili dva, R9 je odabran iz skupine koja sadrži vodik, alkil, supstituirani alkil, acil, aril, supstituirani aril, heteroaril, supstituirani heteroaril, heterocikal i supstituirani heterocikal i R8 je odabran iz skupine koja sadrži vodik, alkil, supstituirani alkil, aril, supstituirani aril, heteroaril, supstituirani heteroaril, heterocikal i supstituirani heterocikal, ili kada W je -NR9- tada R8 i R9, zajedno sa atomom dušika na koji su vezani, mogu se spajati da formiraju heterocikličku ili supstituiranu heterocikličku skupinu, pod uvjetom da kada W je -S(O)n- i n je jedan ili dva, tada R8 nije vodik;
is selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkoxy, substituted alkoxy, amino, substituted amino, aminoacyl, aryl, substituted aryl, halo, heteroaryl, substituted heteroaryl, heterocyclic, substituted heterocyclic, and - XR6 where X is oxygen, -S(O)n- or -NR7- where n is zero, one or two, R6 is selected from the group consisting of alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic, and R7 is hydrogen, alkyl or aryl or, when X is -NR7-, then R7 and R8, together with the nitrogen atom to which they are bound, can be joined to form a heterocyclic or substituted heterocyclic group; 
je odabran iz skupine koja sadrži vodik, alkil, supstituirani alkil, alkoksi; supstituirani alkoksi, amino, supstituirani amino, aminoacil, aril, supstituirani aril, halo, heteroaril, supstituirani heteroaril, heterociklički, supstituirani heterociklički, i - XR6 gdje X je kisik, -S(O)n- ili -NR7- gdje n je nula, jedan ili dva, R6 je odabran iz skupine koja sadrži alkil, supstituirani alkil, aril, supstituirani aril, heteroaril, supstituirani heteroaril, heterocikal i supstituirani heterocikal, i R7 je vodik, alkil ili aril ili, kada X je -NR7-, tada R7 i R6, zajedno sa atomom dušika na koji su vezani, mogu se spajati da formiraju heterocikličku ili supstituiranu heterocikličku skupinu;
R is selected from the group consisting of hydrogen, deuterium and methyl; 
R je odabran iz skupine koja sadrži vodik, deuterij i metil;
R' is selected from the group consisting of hydrogen, deuterium, alkyl and substituted alkyl; alternatively, R and R' and the carbon pendent thereto can be joined to form cycloalkyl, substituted cycloalkyl, heterocyclic or substituted heterocyclic group; 
R' je odabran iz skupine koja sadrži vodik, deuterij, alkil i supstituirani alkil; alternativno, R i R' i atom ugljika koji nose mogu se spojiti da formiraju cikloalkil, supstituirani cikloalkil, heterocikličku ili supstituiranu heterocikličku skupinu;
R" is selected from the group consisting of hydrogen and alkyl or R" together with R' and the nitrogen pendent thereto can be joined to form a heterocyclic or substituted heterocyclic group; 
R" je odabran iz skupine koja sadrži vodik i alkil ili R" zajedno sa R' i dušikom koji nose mogu se spajati da formiraju heterocikličku ili supstituiranu heterocikličku skupinu;
R"' is selected from the group consisting of hydroxy, alkoxy, substituted alkoxy, acyloxy, cycloalkoxy, substituted cycloalkoxy, aryloxy, substituted aryloxy, heteroaryloxy, substituted heteroaryloxy, aryl, -S(O)n-R10 wherein R10 is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl and n is zero, one or two; 
R"' je odabran iz skupine koja sadrži hidroksi, alkoksi, supstituirani alkoksi, aciloksi, cikloalkoksi, supstituirani cikloalkoksi, ariloksi, supstituirani ariloksi, heteroariloksi, supstituirani heteroariloksi, aril, -S(O)n-R10 pri čemu R10 je odabran iz skupine koja sadrži alkil, supstituirani alkil, cikloalkil, supstituirani cikloalkil, aril, supstituirani aril, heteroaril i supstituirani heteroaril i n je nula, jedan ili dva;
"alkoxy" refers to the group "alkyl-O-"; 
"alkoksi" se odnosi na skupinu "alkil-O-";
"substituted alkoxy" refers to the group "substituted alkyl-O-"; 
"supstituirani alkoksi" se odnosi na skupinu "supstituirani alkil-O-";
"aminoacyl" or as a prefix "carbamoyl" or "carboxamide" or "substituted carbamoyl" or "substituted carboxamide" refers to the group -C(O)NR42R42 where each R42 is independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, substituted heterocyclic and where each R42 is joined to form together with the nitrogen atom a heterocyclic or substituted heterocyclic; 
"aminoacil" ili kao prefiks "karbamoil" ili "karboksamid" ili "supstituirani karbamoil" ili "supstituirani karboksamid" se odnosi na skupinu -C(O)NR42R42 gdje svaki R42 je nezavisno odabran iz skupine koja sadrži vodik, alkil, supstituirani alkil, alkenil, supstituirani alkenil, alkinil, supstituirani alkinil, aril, supstituirani aril, cikloalkil, supstituirani cikloalkil, heteroaril, supstituirani heteroaril, heterocikal, supstituirani heterocikal i gdje svaki R42 je spojen da tvori zajedno sa atomom dušika heterocikal ili supstituirani heterocikal;
"substituted alkenyl" refers to alkenyl groups having from 1 to 3 substituents selected from the group consisting of alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, amino, substituted amino, aminoacyl, aryl, substituted aryl, aryloxy, substituted aryloxy, cyano, halogen, hydroxyl, nitro, carboxyl, carboxyl esters, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic; 
"supstituirani alkenil" se odnosi na alkenilne skupine koje imaju od 1 do 3 supstituenata odabranih iz skupine koja sadrži alkoksi, supstituirani alkoksi, acil, acilamino, aciloksi, amino, supstituirani amino, aminoacil, aril, supstituirani aril, ariloksi, supstituirani ariloksi, cijano, halogen, hidroksil, nitro, karboksil, karboksilne estere, cikloalkil, supstituirani cikloalkil, heteroaril, supstituirani heteroaril, heterocikal i supstituirani heterocikal;
"substituted alkynyl" refers to alkynyl groups having from 1 to 3 substituents selected from the group consisting of alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, amino, substituted amino, aminoacyl, aryl, substituted aryl, aryloxy, substituted aryloxy, cyano, halogen, hydroxyl, nitro, carboxyl, carboxyl esters, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic; 
"supstituirani alkinil" se odnosi na alkinilne skupine koje imaju od 1 do 3 supstituenata odabranih iz skupine koja sadrži alkoksi, supstituirani alkoksi, acil, acilamino, aciloksi, amino, supstituirani amino, aminoacil, aril, supstituirani aril, ariloksi, supstituirani ariloksi, cijano, halogen, hidroksil, nitro, karboksil, karboksilne estere, cikloalkil, supstituirani cikloalkil, heteroaril, supstituirani heteroaril, heterocikal i supstituirani heterocikal;
"amino" refers to the group -NH2; 
"amino" se odnosi na skupinu -NH2;
"substituted amino" refers to the group -NR41R41, where each R41 group is independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, substituted heterocyclic, -SO2-alkyl, -SO2-substituted alkyl, -SO2-alkenyl, -SO2-substituted alkenyl, -SO2-cycloalkyl, -SO2-substituted cycloalkyl, -SO2-aryl, -SO2-substituted aryl, -SO2-heteroaryl, -SO2-substituted heteroaryl, -SO2-hctcrocyclic, -SO2 substituted heterocyclic, provided that both R41 groups are not hydrogen; or the R41 groups can be joined together with the nitrogen atom to form a heterocyclic or substituted heterocyclic ring; 
"supstituirani amino" se odnosi na skupinu -NR41R41, gdje svaka R41 skupina je nezavisno odabrana iz skupine koja sadrži vodik, alkil, supstituirani alkil, alkenil, supstituirani alkenil, alkinil, supstituirani alkinil, cikloalkil, supstituirani cikloalkil, aril, supstituirani aril, heteroaril, supstituirani heteroaril, heterocikal, supstituirani heterocikal, -SO2-alkil, -SO2-supstituirani alkil, -SO2-alkenil, -SO2-supstituirani alkenil, -SO2-cikloalkil, -SO2-supstituirani cikloalkil, -SO2-aril, -SO2-supstituirani aril, -SO2-heteroaril, -SO2-supstituirani heteroaril, -SO2- heterocikal, -SO2 supstituirani heterocikal, pod uvjetom da obje R41 skupine nisu vodik; ili R41 skupine mogu se spojiti zajedno sa atomom dušika da formiraju heterociklički ili supstituirani heterociklički prsten;
"aminocarbonyloxy" or as a prefix "carbamoyloxy" or "substituted carbamoyloxy" refers to the groups -OC(O)NR47R47 where each R47 is independently hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic or where each R47 is joined to form, together with the nitrogen atom a heterocyclic or substituted heterocyclic; 
"aminokarboniloksi" ili kao prefiks "karbamoiloksi" ili "supstituirani karbamoiloksi" se odnosi na skupine -OC(O)NR47R47 gdje svaki R47 je nezavisno vodik, alkil, supstituirani alkil, alkenil, supstituirani alkenil, alkinil, supstituirani alkinil, cikloalkil, supstituirani cikloalkil, aril, supstituirani aril, heteroaril, supstituirani heteroaril, heterocikal i supstituirani heterocikal ili gdje svaki R47 je spojen da tvori, zajedno sa atomom dušika heterocikal ili supstituirani heterocikal;
"aminocarbonylamino" refers to the group -NR49C(O)NR49- where R49 is selected from the group consisting of hydrogen and alkyl; 
"aminokarbonilamino" se odnosi na skupinu -NR49C(O)NR49- gdje R49 je odabran iz skupine koja sadrži vodik i alkil;
"aryl" or "Ar" refers to a monovalent aromatic carbocyclic group of from 6 to 14 carbon atoms having a single ring or multiple condensed rings which condensed rings may or may not be aromatic provided that the point of attachment is the aryl group; 
"aril" ili "Ar" se odnosi na monovalentnu aromatsku karbocikličku skupinu sa od 6 do 14 atoma ugljika koja ima jednostruki prsten ili višestruke kondenzirane prstenove koji kondenzirani prstenovi mogu ili ne mogu biti aromatski pod uvjetom da pod uvjetom da je točka spajanja arilna skupina;
"aryloxy" refers to the group aryl-O-; 
"ariloksi" se odnosi na skupinu aril-O-;
"cycloalkyl" refers to cyclic alkyl groups of from 3 to 10 carbon atoms having single or multiple cyclic rings; 
"cikloalkil" se odnosi na cikličke alkilne skupine sa od 3 do 10 atoma ugljika koje imaju jednostruke ili višestruke cikličke prstene;
"substituted cycloalkyl" refers to a cycloalkyl group, having from 1 to 5 substituents selected from the group consisting of oxo (=O), thioxo (=S), alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, amino, substituted amino, aminoacyl, aryl, substituted aryl, aryloxy, substituted aryloxy, cyano, halogen, hydroxyl, nitro, carboxyl, carboxyl esters, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic; 
"supstituirani cikloalkil" se odnosi na cikloalkilnu skupinu, koja ima od 1 do 5 supstituenata odabranih iz skupine koja sadrži okso (=O), tiokso (=S), alkoksi, supstituirani alkoksi, acil, acilamino, aciloksi, amino, supstituirani amino, aminoacil, aril, supstituirani aril, ariloksi, supstituirani ariloksi, cijano, halogen, hidroksil, nitro, karboksil, karboksilne estere, cikloalkil, supstituirani cikloalkil, heteroaril, supstituirani heteroaril, heterocikal i supstituirani heterocikal;
"substituted cycloalkoxy" refers to -O-substituted cycloalkyl groups; 
"supstituirani cikloalkoksi" se odnosi na -O-supstituirane cikloalkilne skupine;
"heteroaryl" refers to an aromatic group of from 1 to 15 carbon atoms and 1 to 4 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur within the ring; 
"heteroaril" se odnosi na aromatsku skupinu od 1 do 15 atoma ugljika i 1 do 4 heteroatoma odabranih iz skupine koja sadrži kisik, dušik i sumpor unutar prstena;
"substituted heteroaryl" refers to heteroaryl groups that are substituted with from I to 3 substituents selected from the same group of substituents defined for substituted aryl; 
"supstituirani heteroaril" se odnosi na heteroarilne skupine koje su supstituirane sa od 1 do 3 supstituenata odabranih iz iste skupine supstituenata definiranih za supstituirani aril;
"heteroaryloxy" refers to the group -O-heteroaryl and "substituted heteroaryloxy" refers to the group -O-substituted heteroaryl; 
"heteroariloksi" se odnosi na skupinu -O-heteroaril i "supstituirani heteroariloksi" se odnosi na skupinu -O-supstituirani heteroaril;
"heterocyclyloxy" refers to the group -O-heterocyclic and "substituted heterocyclyloxy" refers to the group -O-substituted heterocyclic; 
"heterocikliloksi" se odnosi na skupinu -O- heterocikal i "supstituirani heterocikliloksi" se odnosi na skupinu -O-supstituirani heterocikal;
"thiol" or "mercapto" refers to the group -SH; 
"tiol" ili "Merkapto" se odnosi na skupinu -SH;
"substituted alkylthio" refers to the group -S-substituted alkyl; 
"supstituirani alkiltio" se odnosi na skupinu -S-supstituirani alkil;
"substituted cycloalkylthio" refers to the group -S-substituted cycloalkyl; 
"supstituirani cikloalkiltio" se odnosi na skupinu -S-supstituirani cikloalkil;
"heteroarylthio" refers to the group -S-heteroaryl and "substituted heteroarylthio" refers to the group -S-substituted heteroaryl; and "heterocyclicthio" refers to the group -S-heterocyclic and "substituted heterocyclicthio" refers to the group -S-substituted heterocyclic. 
"heteroariltio" se odnosi na skupinu -S-heteroaril i "supstituirani heteroariltio" se odnosi na skupinu -S-supstituirani heteroaril; te "heterociklotio" se odnosi na skupinu -S- heterocikal i "supstituirani heterociklotio " se odnosi na skupinu -S-supstituirani heterocikal.
A compound according to any of the preceding claims, wherein R1 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, halo, alkoxy, aryloxy, substituted aryloxy, substituted aryl, alkylthio, aminoacyl, aryl, substituted amino, heteroaryl, heteroaryloxy, -S(O)n-aryl, -S(O)n-substituted aryl, -S(O)n-heteroaryl, and -S(O)n-substituted heteroaryl, where n is zero, one or two. 
Spoj prema bilo kojem od prethodnih zahtjeva, naznačen time da je R1 odabran iz skupine koja sadrži vodik, alkil, supstituirani alkil, halo, alkoksi, ariloksi, supstituirani ariloksi, supstituirani aril, alkiltio, aminoacil, aril, supstituirani amino, heteroaril, heteroariloksi, -S(O)n-aril, -S(O)n-supstituirani aril, -S(O)n-heteroaril, i -S(O)n-supstituirani heteroaril, gdje n je nula, jedan ili dva.
A compound as in claim 8, wherein R2 is selected from the group consisting of: (4-methoxy)phenylsulfonylamino; 
Spoj prema zahtjevu 8, naznačen time da je R2 odabran iz skupine koja sadrži: (4-metoksi)fenilsulfonilamino;
A compound as in claim 10, wherein R3 is selected from the group consisting of: amino; 
Spoj prema zahtjevu 10, naznačen time da R3 je odabran iz skupine koja sadrži: amino;
A compound as in claim 12, wherein said aryl group is phenyl. 
Spoj prema zahtjevu 12, naznačen time da navedena arilna skupina je fenil.
A compound as in claim 14, wherein R4 is selected from the group consisting of: 
Spoj prema zahtjevu 14, naznačen time da je R4 odabran iz skupine koja sadrži:
A compound as in claim 18, wherein R is selected from the group consisting of phenyl, hydrogen, deuterium and methyl. 
Spoj prema zahtjevu 18, naznačen time da je R odabran iz skupine koja sadrži fenil, vodik, deuterij i metil.
A compound of claim 20, wherein R' is selected from the group consisting of: 
Spoj prema zahtjevu 20, naznačen time da je R' odabran iz skupine koja sadrži:
A compound as in claim 25, wherein said heterocyclic group is pyrrolidinyl. 
Spoj prema zahtjevu 25, naznačen time da navedena heterociklička skupina je pirolidinil.
A compound as in claim 27, wherein R"' is selected from the group consisting of: hydroxy; benzyloxy; 
Spoj prema zahtjevu 27, naznačen time da R"' je odabran iz skupine koja sadrži: hidroksi;
A compound as in claim 29, wherein WR8 is selected from the group consisting of: amino; 
Spoj prema zahtjevu 29, naznačen time da je WR8 odabran iz skupine koja sadrži: amino;
The compounds of the general formula (I), - wherein 
Spojevi opće formule (I), [image] naznačeni time što
and their salts, solvates, N- oxides as well as the salts and solvates thereof. 
i njihove soli, solvati, N-oksidi, kao i njihove soli i solvati.
stands for hydrogen atom or for straight or branched C1-4 alkyl group; 
predstavlja atom vodika ili nerazgranatu ili razgranatu C1-4 alkilnu skupinu;
Z means oxygen atom, sulphur atom, -CHR11-group or -NR12- group - where R11 and R12 independently stand for hydrogen atom, straight or branched C1-4 alkyl group, C3-6 cycloalkyl group, benzyl group, or -CH2-(C1-5 straight or branched acyl)-group, -CH2-CH2-O-(C1-4 straight or branched alkyl)-group or C1-5 straight or branched acyl group; W means nitrogen atom or -CH-group; m is a value of 1, 2 or 3; 
Z označuje atom kisika, atom sumpora, -CHR11- skupinu ili -NR12- skupinu, gdje R11 i R12 neovisno predstavljaju atom vodika, nerazgranatu ili razgranatu C1-4 alkilnu skupinu, C3-6 cikloalkilnu skupinu, benzilnu skupinu ili -CH2-(C1-5 nerazgranati ili razgranati acil)- skupinu, -CH2-CH2-O-(C1-4 nerazgranati ili razgranati alkil)- skupinu ili C1-5 nerazgranatu ili razgranatu acilnu skupinu; W označuje atom dušika ili -CH- skupinu; m ima vrijednost 1, 2 ili 3;
The compounds of the general formula (I) according to Claim 1 or 2, 
Spojevi opće formule (I) u skladu s patentnim zahtjevom 1 ili 2, naznačeni time što
Z means oxygen atom, sulphur atom, -CHR11-group or -NR12- group - where R11 and R12 independently stand for hydrogen atom, straight or branched C1-4 alkyl group, C3-6 cycloalkyl group, benzyl group, or -CH2-(C1-5 straight or branched acyl)-group, -CH2-CH2-O-(C1-4 straight or branched alkyl)-group or C1-5 straight or branched acyl group; 
Z označuje atom kisika, atom sumpora, -CHR11- skupinu ili -NR12- skupinu, gdje R11 i R12 neovisno predstavljaju atom vodika, nerazgranatu ili razgranatu C1-4 alkilnu skupinu, C3-6 cikloalkilnu skupinu, benzilnu skupinu ili -CH2-(C1-5 nerazgranati ili razgranati acil)- skupinu, -CH2-CH2-O-(C1-4 nerazgranati ili razgranati alkil)- skupinu ili C1-5 nerazgranatu ili razgranatu acilnu skupinu;
r is a value of zero or 1; t is a value of zero or 1 -; stands for a phenyl-, benzyl-, thienyl-, or furyl group, optionally substituted with methylenedioxy group, or with one or more, identical or different, straight or branched C1-4 alkyl group, straight or branched C1-4 alkoxy group, hydroxyl group, trifluoromethyl group, cyano group, or halogen atom, or 
r ima vrijednost nula ili 1; t ima vrijednost nula ili 1; predstavlja fenilnu, benzilnu, tienilnu ili furilnu skupinu, izborno supstituiranu s metilendioksi skupinom ili s jednom ili više, istovjetnih ili različitih, nerazgranatih ili razgranatih C1-4 alkilnih skupina, nerazgranatih ili razgranatih C1-4 alkoksi skupina, hidroksilnih skupina, trifluormetilnih skupina, cijano skupina ili atoma halogena, ili