natgillin/translations-raw huggingface dataset:
Therefore, the same problems may be seen if Emtricitabine/Tenofovir disoproxil Zentiva is administered with a third nucleoside analogue.
Stoga će se možda uočiti isti problemi ako se Emtricitabine/Tenofovir disoproxil Zentiva primjenjuje s nekim trećim analogom nukleozida.
Therefore, the time to reach steady state plasma concentration would be expected to occur in approximately 7-8 days.
Prema tome, vrijeme dostizanja koncentracije stanja dinamičke ravnoteže u plazmi očekuje se u roku od 7 do 8 dana.
Therefore, the use of Cimzia during pregnancy is not recommended.
Stoga se ne preporučuje primjenjivati Cimziju u trudnoći.
Therefore, the use of COCs should not be recommended until the breast- feeding mother has completely weaned her child and an alternative contraceptive method should be proposed to women wishing to breastfeed.
Stoga se ne preporučuje primjena KOK-a sve do potpunog prestanka dojenja, a majkama koje žele nastaviti dojiti treba preporučiti drugu metodu kontracepcije.
Therefore, the use of COCs should not be recommended until the nursing mother has completely weaned her child and an alternative contraceptive method should be proposed to women wishing to breastfeed.
Stoga se ne preporučuje primjena KOK-a sve do potpunog prestanka dojenja, a majkama koje žele nastaviti dojiti treba preporučiti drugu metodu kontracepcije.
Therefore, the use of Comtan in children cannot be recommended.
Stoga se ne preporučuje primjena Comtana u djece.
Therefore, the use of Comtess in children cannot be recommended.
Stoga se ne preporučuje primjena Comtessa u djece.
Therefore, the use of Corbilta in children is not recommended.
Stoga se primjena Corbilte u djece ne preporučuje.
Therefore, the use of Edistride is not recommended in patients with moderately or severely reduced
Stoga se primjena lijeka Edistride ne preporučuje u bolesnika s umjereno ili ozbiljno smanjenom funkcijom
Therefore, the use of Entacapone Orion in children cannot be recommended.
Stoga se ne preporučuje primjena Entacapone Oriona u djece.
Therefore, the use of Entacapone Teva in children cannot be recommended.
Stoga se ne preporučuje primjena Entakapona Teva u djece.
Therefore, the use of Irbesartan/Hydrochlorothiazide Teva is not recommended.
Primjena lijeka Irbesartan/Hidroklorotiazid Teva se stoga ne preporučuje.
Therefore, the use of Levodopa/Carbidopa/Entacapone Orion in children is not recommended.
Stoga se primjena Levodopa/Carbidopa/Entacapone Oriona u djece ne preporučuje.
Therefore, the use of Orgalutran is contraindicated in patients with hepatic impairment (see section 4.3).
Stoga je primjena lijeka Orgalutran kontraindicirana u bolesnica s oštećenjem funkcije jetre (vidjeti dio 4.3).
Therefore, the use of Orgalutran is contraindicated in patients with moderate or severe renal impairment (see section 4.3).
Stoga je primjena lijeka Orgalutran kontraindicirana u bolesnica s umjerenim ili teškim oštećenjem funkcije bubrega (vidjeti dio 4.3).
Therefore, the use of PritorPlus is not recommended.
Stoga se ne preporučuje primjena PritorPlusa.
Therefore, the use of Stalevo in children is not recommended.
Stoga se primjena Staleva u djece ne preporučuje.
Therefore, the use of strong CYP3A4 enzyme inducers (e.g. rifampicin, phenobarbital, carbamazepine, phenytoin and St. John’s Wort) with apremilast is not recommended.
Stoga se ne preporučuje primjena jakih induktora enzima CYP3A4 (npr. rifampicin, fenobarbital, karbamazepin, fenitoin i gospina trava) s apremilastom.
Therefore, the use of such combinations is not recommended.
Stoga se primjena takvih kombinacija ne preporučuje.
Therefore, the use of telavancin in patients with pre-existing acute renal failure and in patients with severe renal impairment is contraindicated (see section 4.3).
je primjena telavancina kod bolesnika s već postojećim akutnim zatajenjem bubrega i kod bolesnika s teškim oštećenjem funkcije bubrega kontraindicirana (vidjeti dio 4.3).
Therefore, the use of Xarelto in combination with dual antiplatelet therapy in patients at known increased risk for bleeding should be balanced against the benefit in terms of prevention of atherothrombotic events.
Stoga primjenu lijeka Xarelto u kombinaciji s dvojnom antitrombocitnom terapijom u bolesnika za koje se zna da imaju povećan rizik od krvarenja treba uravnotežiti u odnosu na korist za sprječavanje aterotrombotskih događaja.
Therefore, the use of Xarelto is not recommended in patients receiving concomitant systemic treatment with azole-antimycotics such as ketoconazole, itraconazole, voriconazole and posaconazole or HIV protease inhibitors.
Stoga se primjena lijeka Xarelto ne preporučuje bolesnika koji istodobno sistemski primaju azolne antimikotike poput ketokonazola, itrakonazola, varikonazola i posakonazola, ili inhibitore HIV proteaza.
Therefore, the use of Xarelto is not recommended in patients receiving concomitant systemic treatment with azole-antimycotics such as ketoconazole, itraconazole, voriconazole and posaconazole or HIV protease inhibitors.
Stoga se primjena lijeka Xarelto ne preporučuje u bolesnika koji istodobno sistemski primaju azolne antimikotike poput ketokonazola, itrakonazola, varikonazola i posakonazola, ili inhibitore HIV proteaza.
Therefore, the veterinary medicinal product should only be used in such animals according to a benefit/risk assessment by the responsible veterinarian.
Stoga ovaj veterinarsko-medicinski proizvod se smije primijeniti samo na osnovi procjene odgovornog veterinara, da je korist veća od mogućih štetnih učinaka.
Therefore, the veterinary medicinal product should only be used in such animals according to a benefit/risk assessment by the responsible veterinarian.
Stoga, veterinarsko medicinski proizvod se kod tih životinja treba koristiti na osnovi procjene koristi/rizika odgovornog veterinara.
Therefore, their occurrence after treatment with eslicarbazepine acetate cannot be excluded.
Stoga se njihova pojava nakon liječenjaeslikarbazepinacetatom ne može isključiti.
Therefore, therapeutic effects and/or metabolite levels of medicinal products, including some oral contraceptives, that are substrates for this enzyme may be reduced and their full effects cannot be guaranteed, following co- administration with glycerol phenylbutyrate.
Stoga se terapijski učinci i/ili razine metabolita lijekova, uključujući neke oralne kontraceptive koji su supstrati za ovaj enzim, mogu smanjiti i njihovi puni učinci ne mogu se jamčiti, nakon istodobne primjene glicerolfenilbutirata.
Therefore, there are not sufficient data to recommend the use of MEPACT in patients >30 years of age.
Stoga nema dovoljno podataka da bi se preporučila primjena lijeka MEPACT kod bolesnika starijih od 30 godina.
Therefore, there is a potential for interaction with other concomitantly administered medicinal products that are metabolized primarily by or modulate the activity of CYP3A4 (see section 4.5).
Stoga postoji mogućnost interakcije s drugim istodobno primijenjenim lijekovima koji se metaboliziraju primarno preko CYP3A4 ili moduliraju aktivnost tog enzima (vidjeti dio 4.5).
Therefore, there is little potential for interactions with antiretroviral protease inhibitors, non- nucleosides and other medicinal products metabolised by major P450 enzymes.
Stoga postoji mala mogućnost za interakcije lijeka s antiretrovirusnim inhibitorima proteaze, nenukleozidima te drugim lijekovima koji se metaboliziraju putem glavnih P450 enzima.
Therefore, there is no need to adjust the dosage of Perjeta based on these covariates.
Stoga nema potrebe za prilagođavanjem doze lijeka Perjeta na temelju navedenih kovarijanti.
Therefore, this co-administration should be avoided unless judged strictly necessary (see section 4.5).
Zbog toga se istodobna terapija lopinavira/ritonavira i rifampicina mora izbjegavati ukoliko nije neophodna (vidjeti dio 4.5).
Therefore, this combination is not recommended (see section 4.4).
Ta se kombinacija stoga ne preporučuje (vidjeti dio 4.4.).
Therefore, this medicinal product must be discontinued prior to, or at the time of the test and not be reinstituted until at least 48 hours afterwards, and only after renal function has been re-evaluated and has not deteriorated further (see section 4.5).
Stoga se liječenje ovim lijekom mora prekinuti prije ili za vrijeme pretrage i ne smije se ponovo započeti najmanje 48 sati nakon toga, i to samo kada se funkcija bubrega ponovno ocijeni te ako se nije dodatno pogoršala (vidjeti dio 4.5).
Therefore, this medicinal product must be discontinued prior to, or at the time of the test and not reinstituted until 48 hours afterwards, and only after renal function has been re-evaluated and has not deteriorated further (see section 4.4).
Stoga je potrebno prekinuti primjenu ovog lijeka prije ili u vrijeme pretrage, te se lijek smije ponovno uvesti najmanje 48 sati nakon toga i tek nakon što se funkcija bubrega ponovo ocijenila i nije se dodatno pogoršala (vidjeti dio 4.4).
Therefore, this medicinal product should be used with caution in such patients.
Stoga ovaj lijek treba primjenjivati s oprezom u takvih bolesnika.
Therefore, this medicine should be used with caution in such patients.
Stoga u takvih bolesnika ovaj lijek treba primjenjivati s oprezom.
Therefore, this specific regimen with concomitant administration with high-dose cytarabine (2 g/m2 per day) by continuous infusion over 24 hours is not recommended.
Stoga se ne preporučuje ovaj kombinirani režim s istodobnom primjenom visokih doza citarabina (2 g/m2 na dan) kontinuiranom infuzijom u trajanju od 24 sata.
Therefore, this specific regimen with concomitant administration with high-dose cytarabine (2 g/m2 per day) by continuous infusion over 24 hours is not recommended.
Stoga se ne preporučuje ovaj specifični režim s istodobnom primjenom visokih doza citarabina (2g/m2 na dan) kontinuiranom infuzijom u trajanju od 24 sata.
Therefore, treating patients with Pompe disease with immunosuppressive agents may further increase the risk of developing severe respiratory infections and vigilance is recommended.
Stoga liječenje oboljelih od Pompeove bolesti imunosupresivnim sredstvima može dodatno povećati rizik od razvoja teških respiratornih infekcija te se preporučuje oprez.
Therefore, treatment should be discontinued prior to, or at the time of the test and not reinstituted until 48 hours afterwards, and only after renal function has been re-evaluated and found to be normal (see section 4.4).
Zbog toga treba prekinuti uzimanje lijeka prije ili za vrijeme pretrage, a liječenje se može nastaviti 48 sati nakon pretrage i to samo kada se utvrdi da je funkcija bubrega normalna (vidjeti dio 4.4).
Therefore, treatment should be discontinued prior to, or at the time of the test and not reinstituted until 48 hours afterwards, and only after renal function has been re-evaluated and found to be normal (see section 4.5).
Zbog toga treba prekinuti uzimanje lijeka prije ili za vrijeme pretrage, a liječenje se može nastaviti 48 sati nakon pretrage i to tek nakon što se ponovnom procjenom utvrdi da je funkcija bubrega normalna (vidjeti dio 4.5).
Therefore, treatment with denosumab may impair bone growth in children with open growth plates and may inhibit eruption of dentition.
Dakle liječenje denosumabom može narušiti rast kostiju u djece s otvorenim pločama rasta te može inhibirati izbijanje zuba.
Therefore, treatment with Procox does not resolve clinical symptoms arising from mucosal damage (e.g. diarrhoea) that have arisen before treatment.
Stoga, primjena Procox-a ne rješava kliničke simptome koji su uzrokovani oštećenjem sluznice (npr. proljev) koji su nastali prije tretiranja.
Therefore, unless your doctor tells you to stop treatment, it is important to keep taking CELSENTRI correctly, as described above.
Zbog toga je, osim ako Vam liječnik ne savjetuje da prekinete uzimati lijek, važno redovito uzimati CELSENTRI, kao što je to ranije opisano.
Therefore, until more experience is gained, breast- feeding should be discontinued when Cubicin is administered to nursing women.
Stoga, dok se ne bude raspolagalo većim brojem podataka, treba prekinuti dojenje ukoliko se Cubicin primjenjuje u dojilja.
Therefore, upon re- administration of eptotermin alfa, a risk of developing autoimmunity towards the endogenous BMP proteins may exist.
Stoga u slučaju ponovne primjene eptotermina alfa postoji rizik od razvoja autoimuniteta prema endogenim proteinima BMP.
Therefore, use of Kalydeco in these patients is not recommended.
Stoga se ne preporučuje primjena lijeka Kalydeco u tih bolesnika.
Therefore, vandetanib is not indicated for use in paediatric patients.
Stoga, vandetanib nije namijenjen za primjenu u pedijatrijskih bolesnika.
Therefore, vardenafil should be administered to these patients only after careful benefit-risk assessment.
Stoga se vardenafil kod ovih bolesnika smije primjenjivati samo nakon pažljive procjene koristi i rizika.
Therefore, varenicline can effectively block nicotine's ability to fully activate α4β2 receptors and the mesolimbic dopamine system, the neuronal mechanism underlying reinforcement and reward experienced upon smoking.
Stoga vareniklin može djelotvorno blokirati sposobnost nikotina da u potpunosti aktivira α4β2 receptore i mezolibički dopaminski sustav - neuronski mehanizam u podlozi poticaja i doživljaja ugode nakon pušenja.
Therefore, varenicline can effectively block nicotine's ability to fully activate α4β2 receptors and the mesolimbic dopamine system, the neuronal mechanism underlying reinforcement and reward experienced upon smoking.
Stoga vareniklin može djelotvorno blokirati sposobnost nikotina da u potpunosti aktivira α4β2 receptore i mezolibički dopaminski sustav – neuronski mehanizam u podlozi poticaja i doživljaja ugode nakon pušenja.
Therefore, Vectibix should not be administered in combination with bevacizumab containing chemotherapy (see sections 4.5 and 5.1).
Zbog navedenog, Vectibix se ne smije primjenjivati u kombinaciji s kemoterapijskim protokolom koji sadrži bevacizumab (vidjeti dio 4.5 i 5.1).
Therefore, vincristine should be given in a timely manner before administration of Oncaspar in order to minimise toxicity.
Stoga, vinkristin treba pravovremeno primijeniti prije primjene Oncaspara radi smanjenja toksičnosti na najmanju moguću mjeru.
Therefore, Vipdomet should be discontinued prior to, or at the time of, the test and not reinstituted until 48 hours afterwards, and only after renal function has been re-evaluated and found to be normal (see section 4.4).
Stoga se prije ili u vrijeme pretrage treba prekinuti primjena Vipdometa i ponovno nastaviti nakon najmanje 48 sati, i to tek nakon što se ponovno procijeni funkcija bubrega i potvrdi da je normalna (vidjeti dio 4.4).
Therefore, Vipdomet should be discontinued prior to, or at the time of, the test and not reinstituted until 48 hours afterwards, and only after renal function has been re-evaluated and found to be normal (see section 4.5).
Stoga se prije ili u vrijeme pretrage treba prekinuti primjena Vipdometa i ponovno nastaviti nakon najmanje 48 sati, i to tek nakon što se ponovno procijeni funkcija bubrega i potvrdi da je normalna (vidjeti dio 4.5).
Therefore, virological response should be closely monitored.
Stoga je potrebno pomno pratiti virološki odgovor.
Therefore, Vitekta should not be used during breast- feeding.
Stoga se Vitekta ne bi trebala primjenjivati tijekom dojenja.
Therefore, Voncento is not recommended to be used in children with haemophilia A under the age of 12 years.
Stoga se Voncento ne preporučuje za primjenu u djece s hemofilijom A u dobi mlađoj od 12 godina.
Therefore, when co-administered with substrates of OAT 3, such as cefaclor, benzylpenicillin, ciprofloxacin, indomethacin, ketoprofen, furosemide, cimetidine, methotrexate, zidovudine, caution is recommended.
Stoga se preporučuje oprez kod istodobne primjene leflunomida sa supstratima OAT3, kao što su cefaklor, benzilpenicilin, ciprofloksacin, indometacin, ketoprofen, furosemid, cimetidin, metotreksat, zidovudin.
Therefore, when injecting Orgalutran in the morning treatment with Orgalutran should be continued throughout the gonadotrophin treatment period including the day of triggering ovulation.
Stoga, kada se Orgalutran primjenjuje ujutro, liječenje ovim lijekom treba nastaviti cijelo vrijeme liječenja gonadotropinom, uključujući i dan kada se izaziva ovulacija.
Therefore, when ISENTRESS is co-administered with calcium carbonate containing antacids no dose adjustment is required.
Stoga pri istodobnoj primjeni lijeka ISENTRESS i antacida koji sadrže kalcijev karbonat nije potrebno prilagođavati dozu.
Therefore, when PARP proteins are blocked, the damaged DNA in cancer cells cannot be repaired, and, as a result, the cancer cells die.
Stoga, ako su PARP proteini inhibirani, oštećenje DNK u stanica raka ne može se popraviti, i to rezultira smrću stanica raka.
Therefore, when such toxicities occur or if for any other reason A771726 needs to be cleared rapidly from the body, the washout procedure has to be followed.
Stoga, pri pojavi tih toksičnosti ili potrebe za brzim uklanjanjem A771726 iz organizma zbog bilo kojeg drugog razloga treba obaviti ispiranj ("washout" postupak).
Therefore, when such toxicities occur or if for any other reason A771726 needs to be cleared rapidly from the body, the washout procedure has to be followed.
Stoga, pri pojavi tih toksičnosti ili potrebe za brzim uklanjanjem A771726 iz organizma zbog bilo kojeg drugog razloga treba obaviti postupak ispiranja („washout“).
Therefore, when such toxicities occur or if for for any other reason A771726 needs to be cleared rapidly from the body, the washout procedure has to be followed.
Stoga, pri pojavi tih toksičnosti ili potrebe za brzim uklanjanjem A771726 iz organizma zbog bilo kojeg drugog razloga treba obaviti postupak ispiranja ("washout").
Therefore, when such toxicities occur or if for for any other reason A771726 needs to be cleared rapidly from the body, the washout procedure has to be followed.
Stoga, pri pojavi tih toksičnosti ili potrebe za brzim uklanjanjem A771726 iz organizma zbog bilo kojeg drugog razloga treba obaviti postupak ispiranja („washout“).
Therefore, when switching between fentanyl containing medicinal products indicated for treatment of breakthrough pain, including intranasal formulations, it is essential that patients are again titrated with the new medicinal product, and not switched on a dose-for-dose (microgram-for- microgram) basis.
Stoga je pri prelaženju s jednog lijeka s fentanilom indiciranog za liječenje probijajuće boli na drugi takav lijek, uključujući intranazalne pripravke, bitno bolesnike ponovno titrirati za taj novi lijek, a ne zamijeniti lijekove po načelu doza za dozu (mikrogram za mikrogram).
Therefore, when taking Xaluprine, avoid excessive exposure to sunlight, wear protective clothing and use protective sunscreen with a high protection factor
Stoga pri uzimanju Xaluprinea izbjegavajte prekomjerno izlaganje sunčevoj svjetlosti, nosite zaštitnu odjeću i upotrebljavajte zaštitnu kremu za sunčanje s visokim zaštitnim faktorom.
Therefore, when temsirolimus is co-administered with medicinal products which are P-gp substrates (e.g. digoxin, vincristine, colchicine, dabigatran, lenalidomide, and paclitaxel) close monitoring for adverse events related to the co-administered medicinal products should be observed.
Stoga, kad se temsirolimus primjenjuje istodobno s lijekovima koji su supstrati P-gp (npr. digoksin, vinkristin, kolhicin, dabigatran i paklitaksel) potreban je pažljiv nadzor zbog štetnih događaja povezanih s istodobnom primjenom ovih lijekova.
Therefore, when using antiviral medicinal products that are human thymidine kinase substrates, monitor for possible decreased efficacy of the antiviral medicinal product, and consider switching to an alternative antiviral medicinal product that is not a human thymidine kinase substrate, such as lamivudine, zalcitabine, didanosine and abacavir (see section 5.1).
Zbog toga, kod primjene antivirusnih lijekova koji su supstrati ljudske timidin kinaze, treba pratiti moguću smanjenu učinkovitost antivirusnog lijeka i treba razmisliti o prelasku na drugi antivirusni lijek koji nije supstrat ljudske timidin kinaze, kao što su lamivudin, zalcitabin, didanozin i abakavir (vidjeti dio 5.1).
Therefore, when warfarin is co-administered, close INR follow-up and monitoring monitoring is recommended.
Stoga, kod istodobne primjene varfarina, preporučuje se pomno praćenje i nadzor INR-a.
Therefore, when warfarin or anothercoumarin anticoagulant is co-administered, close international normalised ratio (INR) follow-up and monitoring is recommended.
Stoga, kada se varfarin i drugi kumarinski antikoagulansi primjenjuju istodobno s leflunomidom, preporučuje se pomno praćenje i nadzor internacionalnog normaliziranog omjera (engl. international normalised ratio, INR).
Therefore, whenever possible, Vitekta should be administered with a fully active ritonavir-boosted protease inhibitor and a second fully active antiretroviral agent to minimise the potential for virologic failure and the development of resistance (see section 5.1).
Stoga je, kad god je moguće, lijek Vitekta potrebno primijeniti s potpuno aktivnim, ritonavirom pojačanim, inhibitorom proteaze i drugim potpuno aktivnim antiretrovirusnim lijekom kako bi se umanjila mogućnost virološkog neuspjeha i razvoja rezistencije (vidjeti dio 5.1).
Therefore, withholding of antihypertensive treatments should be considered for 12 hours prior to and throughout each Gazyvaro infusion and for the first hour after administration.
Stoga, potrebno je razmotriti suzdržavanje od antihipertenziva 12 sati prije i tijekom svake infuzije lijeka Gazyvaro te još sat vremena nakon primjene lijeka.
Therefore, women of child bearing potential should use effective contraceptive measures when receiving a course of treatment with LEMTRADA and for 4 months following that course of treatment.
Stoga žene u reproduktivnoj dobi moraju primjenjivati djelotvorne kontracepcijske mjere tijekom liječenja lijekom LEMTRADA i 4 mjeseca nakon toga ciklusa liječenja.
Therefore, women of childbearing potential must use adequate contraception during treatment with Zebinix, and up to the end of the current menstruation cycle after the treatment has been discontinued (see sections 4.4 and 4.6).
Stoga, žene u generativnoj dobi moraju koristiti odgovarajuću kontracepciju tijekom liječenja Zebinixom, a sve do kraja tekućeg ciklusa menstruacije nakon što je liječenje prekinuto (vidjeti dijelove 4.4 i 4.6).
Therefore, women should not breast-feed during treatment with Vargatef.
Stoga žene ne smiju dojiti tijekom liječenja Vargatefom.
Therefore, women taking everolimus should not breast-feed.
Stoga žene koje uzimaju everolimus ne smiju dojiti.
Therefore, women taking Odomzo must take effective measures to prevent pregnancy during treatment and for 20 months after stopping it.
Stoga, žene koje uzimaju lijek Odomzo moraju poduzeti djelotvorne mjere kako bi spriječile trudnoću tijekom terapije i tijekom 20 mjeseci nakon prestanka uzimanja terapije.
Therefore, wounds with areas of full-thickness and deep burn should be autografted as soon as possible after NexoBrid debridement (see section 5.1 for study results).
Stoga rane kod kojih su prisutne opekline pune debljine kože i duboke opekline treba nakon debridmana NexoBridom čim prije pokriti presatkom vlastite kože (vidjeti dio 5.1 za rezultate ispitivanja).
Therefore, Xarelto is to be used with caution in these patients.
Stoga se Xarelto u tih bolesnika treba primjenjivati s oprezom.
Therefore, Xiapex must be injected only into the Peyronie’s plaque and care should be taken to avoid injecting into the urethra, nerves, blood vessels, corpora cavernosa or other collagen-containing structures of the penis.
Zbog toga se Xiapex mora injicirati samo u Peyronijev plak i treba paziti da ga se ne bi injiciralo u uretru, živce, krvne žile, kavernozna tijela ili druge strukture penisa koje sadrže kolagen.
Therefore, you may be at risk of getting an infection while you are taking Afinitor. impact your kidney function.
Zbog toga možete biti u opasnosti od infekcije dok uzimate Afinitor. utjecati na funkciju bubrega.