natgillin/translations-raw huggingface dataset:
Swords Laboratories T/A Lawrence Laboratories Unit 12 & 15, Distribution Centre Shannon Industrial Estate Shannon, Co. Clare, V14 DD39 
Swords Laboratories T/A Lawrence Laboratories Unit 12 & 15, Distribution Centre Shannon Industrial Estate Shannon, Co.
Additionally, 34 (47%) received diuretics, 23 (32%) received corticosteroids, and 20 (27%) received both corticosteroids and diuretics. 
Uz to, 34 (47%) bolesnika primala su diuretike, 23 (32%) kortikosteroide, a njih 20 (27%) i kortikosteroide i diuretike.
• Hold plunger to prevent it from moving. 
• Držite klip kako se ne bi pomicao.
Discard any unused suspension 60 days after constitution. 
Baciti svu neupotrijebljenu suspenziju 60 dana nakon rekonstitucije.
It could not be determined whether these mucocutaneous adverse reactions were directly related to SPRYCEL or to concomitant medicinal product. 
Nije se moglo utvrditi da li je ta mukokutana nuspojava direktno povezana s lijekom SPRYCEL ili s istodobno primjenjivanim lijekovima.
Clinically relevant interactions 
Klinički značajne interakcije
Pack size: 1 bottle 
Veličina pakiranja:1 boca
All patients were extensively pretreated. 
Svi su bolesnici prethodno bili opsežno liječeni.
SPRYCEL with food and drink Do not take SPRYCEL with grapefruit or grapefruit juice. 
SPRYCEL s hranom i pićem SPRYCEL se ne smije uzimati s grejpom niti sokom od grejpa.
The primary efficacy endpoint was 3-year event-free survival (EFS), which was 65.5% (55.5, 73.7). 
Primarna mjera ishoda za djelotvornost bilo je 3 godišnje preživljenje bez događaja (EFS), čija je stopa iznosila 65,5% (55,5; 73,7).
After constitution, shake bottle well before each use. 
Nakon rekonstitucije, bocu treba dobro protresti prije svake uporabe.
*Adjusted for Hasford Score and indicated statistical significance at a pre-defined nominal level of significance. 
* Prilagođeno prema rezultatu po Hasfordu i navedena statistička značajnost prema unaprijed određenoj nominalnoj razini značajnosti.
Most resistant patients (72%) had received > 600 mg imatinib. 
Većina bolesnika s rezistencijom (72%) primala je >600 mg imatiniba.
SPRYCEL is not to be used during pregnancy unless clearly necessary. 
SPRYCEL se ne smije uzimati tijekom trudnoće osim ako to nije jasno neophodno.
Wash the outside and the inside of the syringe with water and allow to air dry after each use to reuse for the next day. 
Nakon svake uporabe isperite vanjski i unutarnji dio štrcaljke vodom i ostavite da se osuši na zraku, kako biste je pripremili za ponovnu uporabu sljedeći dan.
MONTHS 
MJESECI
The relevance of the findings from the rat carcinogenicity study for humans is not known. 
Važnost ovih nalaza dobivenih u ispitivanjima kancerogenosti na štakorima za ljude nije poznata.
Dosing for children and adolescents is on the basis of body weight (see Table 1). 
Doziranje za djecu i adolescente temelji se na tjelesnoj težini (vidjeti Tablicu 1).
Do not take SPRYCEL if you are allergic to dasatinib or any of the other ingredients of this medicine (listed in section 6). 
ako ste alergični na dasatinib ili neki drugi sastojak ovog lijeka (naveden u dijelu 6.).
• Store the constituted oral suspension in a refrigerator (2°C - 8°C). 
• Čuvajte pripremljenu oralnu suspenziju u hladnjaku (2°C - 8°C).
Both men and women taking SPRYCEL will be advised to use effective contraception during treatment. 
Muškarcima i ženama koji uzimaju SPRYCEL savjetuje se da tijekom liječenja koriste djelotvornu kontracepciju.
Dasatinib should be administered with caution to patients who have or may develop prolongation of QTc. 
Dasatinib se mora primjenjivati s oprezom u bolesnika koji imaju ili u kojih se može razviti produženje QTc intervala.
Hazard ratio (HR) within 12 months (99.99% CI) 
Omjer hazarda (HR) unutar 12 mjeseci (99,99% CI)
Ask your doctor or pharmacist for advice if you have a liver or kidney disease. 
Pitajte svoj liječnika ili ljekarnika za savjet ako imate jetrenu ili bubrežnu bolest.
These instructions show you how to give a dose of SPRYCEL oral suspension to the patient. 
Ove upute pokazuju kako dati dozu SPRYCEL oralne suspenzije bolesniku.
Cytogenetic response within 12 months cCCyRa p< 0.007* 
Citogenetski odgovor unutar 12 mjeseci cCCyRa p< 0,007*
Nine (12%) patients underwent therapeutic thoracentesis. 
Devet (12%) bolesnika bilo je podvrgnuto terapijskoj torakocentezi.
Time-to MMR 
Vrijeme do MMR
There may be a vacuum pulling the plunger back into barrel. 
Može se stvoriti vakuum koji će povlačiti klip natrag u tijelo štrcaljke.
Note that the markings on the syringe are in mL. 
Imajte na umu da se oznake na štrcaljki odnose na mililitre (ml).
This case was a Grade 1 osteopenia. 
Radilo se o osteopeniji 1. stupnja.
Take special care when driving or using machines in case you experience side effects such as dizziness and blurred vision. 
Budite osobito oprezni pri vožnji ili radu na strojevima u slučaju da dobijete nuspojave poput omaglice ili zamagljenog vida.
SPRYCEL film-coated tablets and SPRYCEL powder for oral suspension are not bioequivalent. 
SPRYCEL filmom obložene tablete i SPRYCEL prašak za oralnu suspenziju nisu bioekvivalentni.
• Put closure back on the bottle and close tightly. 
• Vratite zatvarač na bocu i čvrsto je zatvorite.
Patients who are able to swallow tablets and who desire to switch from SPRYCEL powder for oral suspension to SPRYCEL tablets or patients who are not able to swallow tablets and who desire to switch from tablets to oral suspension, may do so, provided that the correct dosing recommendations for the dosage form are followed. 
Bolesnici koji mogu progutati tablete i žele prijeći sa SPRYCEL praška za oralnu suspenziju na SPRYCEL tablete, odnosno bolesnici koji ne mogu progutati tablete i žele prijeći s tableta na oralnu suspenziju, mogu to učiniti pod uvjetom da se slijede točne preporuke za doziranje za odabrani farmaceutski oblik.
Film-coating Hypromellose Titanium dioxide (E171) Macrogol 400 
Film ovojnica hipromeloza titanijev dioksid (E171) makrogol 400
If the episode does not improve within approximately one week, a course of diuretics or corticosteroids or both concurrently should be considered (see sections 4.4 and 4.8). 
Ako se ova epizoda ne poboljša u roku od približno tjedan dana, treba razmotriti primjenu diuretika ili kortikosteroida ili obaju istodobno (vidjeti dijelove 4.4 i 4.8).
Dosing is on the basis of body weight (see Table 1). 
Doziranje se temelji na tjelesnoj težini (vidjeti Tablicu 1).
By 1 year 5%, p<.2394 
Do 1. godine 5%, p<0,2394
Benzoic acid and benzoates 
Benzoatna kiselina i benzoati
What you need to know before you take SPRYCEL 
Što morate znati prije nego počnete uzimati SPRYCEL
Step 4: Write the date of expiry of the constituted oral suspension on the bottle label (the date of expiry of the constituted oral suspension is 60 days from the date of constitution). 
4. korak: Zapišite datum isteka roka valjanosti rekonstituirane oralne suspenzije na naljepnicu boce (datum isteka roka valjanosti rekonstituirane oralne suspenzije je 60 dana od datuma rekonstitucije).
Dose (maximum dose per day) Original starting dose 
Doza (maksimalna dnevna doza) Prvobitna početna doza
This should be taken into account in patients with diabetes mellitus. 
To treba uzeti u obzir u bolesnika sa šećernom bolešću.
Therefore, caution should be recommended when driving a car or operating machines. 
Stoga se mora preporučiti oprez pri upravljanju vozilima i radu na strojevima.
# DEATHS / # Land Patient 
# SMRTI / # bolesnika
Instructions for administration to the patient 
Upute za primjenu bolesniku
Renal changes in monkeys treated for up to 9 months were limited to an increase in background kidney mineralisation. 
Bubrežne promjene u majmuna liječenih do 9 mjeseci bile su ograničene na porast pozadinske mineralizacije u bubrezima.
Certain medicines may interfere with the effect of SPRYCEL when taken together. 
Određeni lijekovi mogu utjecati na djelovanje lijeka SPRYCEL ako se uzimaju istodobno.
• 1 SPRYCEL oral suspension bottle containing a white to yellow opaque suspension. 
• 1 bocu SPRYCEL oralne suspenzije koja sadrži bijelu do žutu neprozirnu suspenziju
What SPRYCEL contains 
Što SPRYCEL sadrži
If PAH is confirmed, dasatinib should be permanently discontinued. 
Ako se potvrdi PAH, primjena dasatiniba mora se trajno prekinuti.
Results described below are based on a minimum of 2 years and 7 years follow-up after the start of dasatinib therapy. 
Niže navedeni rezultati temelje se na podacima nakon najmanje 2 godine i 7 godina praćenja od početka liječenja dasatinibom.
ANC: absolute neutrophil count *lower tablet dose not available 
ABN: apsolutni broj neutrofila *nije dostupna tableta u nižoj dozi
Depending on how you respond to the treatment, your doctor may suggest a higher or lower dose, or even stopping treatment briefly. 
Ovisno o odgovoru na liječenje, liječnik Vam može preporučiti višu ili nižu dozu ili čak nakratko prekinuti liječenje.
The random inter-occasion variability in exposure is not expected to affect the cumulative exposure and efficacy or safety. 
Ne očekuje se da će ta nasumična intraindividualna varijabilnost u izloženosti u pojedinim vremenskim točkama utjecati na kumulativnu izloženost te djelotvornost ili sigurnost.
If you or your child could be allergic, ask your doctor for advice. 
U slučaju da biste Vi ili Vaše dijete mogli biti alergični, potražite savjet svoga liječnika.
In patients, dasatinib has a large apparent volume of distribution (2,505 L), coefficient of variation (CV% 93%), suggesting that the medicinal product is extensively distributed in the extravascular space. 
Dasatinib u bolesnika ima velik prividni volumen distribucije (2505 l) i koeficijent varijacije (CV% 93%), što ukazuje na to da se lijek široko raspodjeljuje u ekstravaskularnom prostoru.
Refer to the package leaflet for more detailed instructions for use. 
Vidjeti uputu o lijeku za detaljnije upute za uporabu.
Film-coated tablets should not be dispersed as the exposure in patients receiving a dispersed tablet is lower than in those swallowing a whole tablet. 
Filmom obložene tablete ne smiju se otapati jer je izloženost lijeku u bolesnika koji uzmu rastopljenu tabletu manja nego u onih koji progutaju cijelu tabletu.
However, when antacids were administered 2 hours prior to a single dose of SPRYCEL, no relevant changes in dasatinib concentration or exposure were observed. 
Međutim, kad su antacidi bili primijenjeni 2 sata prije pojedinačne doze lijeka SPRYCEL, nisu bile opažene nikakve značajne promjene u koncentraciji dasatiniba ili izloženosti dasatinibu.
Dasatinib and its metabolites are minimally excreted via the kidney. 
Dasatinib i njegovi metaboliti minimalno se izlučuju putem bubrega.
SPRYCEL tablets can be taken with or without a meal. 
SPRYCEL tablete mogu se uzimati uz obrok ili bez njega.
In people with ALL, white cells called lymphocytes multiply too quickly and live too long. 
U osoba s ALL, bijele krvne stanice koje se zovu limfociti prebrzo se množe i predugo žive.
For storage conditions after constitution of the medicinal product, see section 6.3. 
Za uvjete čuvanja nakon rekonstitucije lijeka vidjeti dio 6.3.
Grade 3 or 4 pleural effusion may require thoracocentesis and oxygen therapy. 
Pleuralni izljev stupnja 3. ili 4. može zahtijevati izvođenje torakocenteze i terapiju kisikom.
Results are shown in Table 15. 
Rezultati su prikazani u Tablici 15.
Pharmacotherapeutic group: antineoplastic agents, protein kinase inhibitors, ATC code: L01XE06 
Farmakoterapijska skupina: antineoplastički lijekovi, inhibitori protein kinaze, ATK oznaka: L01XE06
In general, there was no association of decreased calcium with clinical symptoms. 
Općenito, snižene vrijednosti kalcija nisu bile povezane s kliničkim simptomima.
No studies have been performed to evaluate dasatinib interaction with other protein-bound medicinal products. 
Nisu provedena ispitivanja kojima bi se mogle utvrditi interakcije dasatiniba s lijekovima vezanima na proteine.
Accelerated phase CML 
Faza ubrzanja KML
Efficacy results are presented in Tables 12 and 13. 
Rezultati djelotvornosti prikazani su u Tablicama 12 i 13.
The pharmacokinetics of dasatinib were evaluated in 229 adult healthy subjects and in 84 patients. 
Farmakokinetika dasatiniba ispitana je u 229 zdravih odraslih ispitanika i 84 bolesnika.
• If the amount needed is greater than 11 mL, it must be split into 2 doses as shown below: 
• Ako je potrebna količina veća od 11 ml, mora se podijeliti na 2 doze, kako je navedeno u nastavku:
When this rate was based on the 85 patients with evaluable Ig/TCR assessments, the estimate was 89.4%. 
Kad se ta stopa izračunavala na temelju 85 bolesnika u kojih su se mogli ocijeniti podaci za Ig/TCR, procijenjena je na 89,4%.
If marrow cellularity is >10%, resumption of treatment with SPRYCEL may be considered. 
Ako je celularnost koštane srži > 10%, može se razmotriti nastavak liječenja lijekom SPRYCEL.
ALLOW TO AIR DRY AFTER EACH USE 
NAKON SVAKE UPORABE OSTAVITI DA SE OSUŠI NA ZRAKU
This is because SPRYCEL could cause hepatitis B to become active again, which can be fatal in some cases. 
To je potrebno jer SPRYCEL može uzrokovati ponovnu aktivaciju hepatitisa B što u nekim slučajevima može rezultirati smrtnim ishodom.
With the patient in an upright position, place the tip of the syringe into the mouth between the side of the mouth and the tongue. 
Dok je bolesnik u uspravnom položaju, stavite mu vrh štrcaljke između ruba usta i jezika.
Outer Carton: 2D barcode carrying the unique identifier included. 
Kutija: Sadrži 2D barkod s jedinstvenim identifikatorom.
It can be taken with or without a meal and should be taken consistently either in the morning or in the evening (see section 5.2). 
Može se uzeti uz obrok ili bez njega, ali se mora uzimati uvijek dosljedno ili ujutro ili navečer (vidjeti dio 5.2).
At the request of the European Medicines Agency, Whenever the risk management system is modified, especially as the result of new information being received that may lead to a significant change to the benefit/risk profile or as the result of an important (pharmacovigilance or risk minimisation) milestone being reached. 
Ažurirani RMP treba dostaviti: na zahtjev Europske agencije za lijekove; prilikom svake izmjene sustava za upravljanje rizikom, a naročito kada je ta izmjena rezultat primitka novih informacija koje mogu voditi ka značajnim izmjenama omjera korist/rizik, odnosno kada je izmjena rezultat ostvarenja nekog važnog cilja (u smislu farmakovigilancije ili minimizacije rizika).
There was no significant difference of dasatinib PK between children and adolescents. 
Nije bilo značajne razlike u farmakokinetici dasatiniba između djece i adolescenata.
Durability of response and estimated survival rates provide additional evidence of dasatinib clinical benefit. 
Trajnost odgovora i procjena stope preživljenja dodatni su dokazi povoljnog kliničkog djelovanja dasatiniba.
SPRYCEL inhibits the growth of these leukaemic cells. 
SPRYCEL sprječava rast tih leukemijskih stanica.
However, in an in vivo single-dose study in conscious telemetered monkeys, there were no changes in QT interval or ECG wave form. 
Međutim, u telemetrijskom ispitivanju in vivo pojedinačne doze u budnih majmuna nije bilo promjena u QT intervalu ili obliku EKG valova.
Do not take medicines that neutralise stomach acids (antacids such as aluminium hydroxide or magnesium hydroxide) in the 2 hours before or 2 hours after taking SPRYCEL. 
Ne uzimajte lijekove koji neutraliziraju kiselinu u želucu (antacidi poput aluminijevog hidroksida ili magnezijevog hidroksida) 2 sata prije ili 2 sata poslije uzimanja lijeka SPRYCEL.
How long to take SPRYCEL 
Koliko dugo uzimati SPRYCEL
a Confirmed complete cytogenetic response (cCCyR) is defined as a response noted on two consecutive occasions (at least 
Potvrđen potpuni citogenetski odgovor (cCCyR) definira se kao odgovor zabilježen na dva uzastopna pregleda (u razmaku od najmanje 28 dana).
For oral use after constitution. 
Primjena kroz usta nakon rekonstitucije.
Women of childbearing potential/contraception in males and females Both sexually active men and women of childbearing potential should use effective methods of contraception during treatment. 
Žene u reproduktivnoj dobi/kontracepcija u muškaraca i žena Muškarci i žene u reproduktivnoj dobi koji su spolno aktivni trebaju koristiti učinkovite metode kontracepcije tijekom liječenja.
Common depression, insomnia 
Često depresija, nesanica
Rare aplasia pure red cell 
Rijetko aplazija čiste crvene krvne loze
In rats, minimal to mild decreases in erythrocyte parameters were accompanied by bone marrow changes; similar changes occurred in monkeys at a lower incidence. 
U štakora su minimalna do umjerena smanjenja parametara eritrocita bila praćena promjenama u koštanoj srži; slične promjene nastupile su u majmuna, ali uz nižu incidenciju.
Data was pooled across two studies and showed that dasatinib was rapidly absorbed. 
Podaci su objedinjeni iz dvaju ispitivanja, a pokazali su da se dasatinib brzo apsorbira.
In vitro data indicate a potential risk for interaction with CYP2C8 substrates, such as glitazones. 
Podaci iz ispitivanja in vitro pokazuju da postoji i potencijalni rizik od interakcije sa supstratima CYP2C8, kao što su glitazoni.
Ask your doctor or pharmacist for advice if you are pregnant or breast feeding. 
Pitajte svog liječnika ili ljekarnika za savjet ako ste trudni ili dojite.
These effects occurred at doses that did not produce maternal toxicity, indicating that dasatinib is a selective reproductive toxicant from implantation through the completion of organogenesis. 
Ti su se učinci javili pri dozama koje nisu imale toksične učinke na majku, što znači da dasatinib ima selektivne toksične učinke na reprodukciju od faze implantacije do završetka organogeneze.
Following resolution of the first episode, reintroduction of dasatinib at the same dose level should be considered. 
Nakon povlačenja prve epizode, treba razmotriti ponovno uvođenje dasatiniba u istoj dozi.
• If the amount needed is greater than 11 mL, it must be split into 2 doses as indicated in Table 16. 
• Ako je potrebna količina veća od 11 ml, mora se podijeliti na 2 doze, kako je navedeno u Tablici
In mice, dasatinib induced immunosuppression, which was dose-related and effectively managed by dose reduction and/or changes in dosing schedule. 
U miševa je dasatinib izazivao imunosupresiju, koja je ovisila o dozi i učinkovito se rješavala smanjenjem doze i/ili promjenama u rasporedu doziranja.
During the consolidation blocks of chemotherapy, CBCs should be performed every 2 days until recovery (see sections 4.2 and 4.8). 
Tijekom konsolidacijskih blokova kemoterapije kompletnu krvnu sliku treba raditi svaka 2 dana do oporavka (vidjeti dijelove 4.2 i 4.8).
Caution should be exercised if patients are required to take medicinal products that inhibit platelet function or anticoagulants. 
Nužno je biti na oprezu ako bolesnici moraju uzimati lijekove koji inhibiraju funkciju trombocita ili antikoagulanse.
SPRYCEL powder for oral suspension is to be constituted as follows: Note: If you have to constitute more than one bottle, complete one bottle at a time. 
SPRYCEL prašak za oralnu suspenziju treba rekonstituirati na sljedeći način: Napomena: Ako morate rekonstituirati sadržaj više od jedne boce, rekonstituirajte jednu po jednu bocu.
The outcome of patients with bone marrow transplantation after dasatinib treatment has not been fully evaluated. 
Ishod bolesnika s transplantacijom koštane srži nakon liječenja dasatinibom nije još u potpunosti ocijenjen.
• Shake well before each use. 
• Dobro je protresite prije svake primjene.
Efficacy was also assessed in patients who were intolerant to imatinib. 
Djelotvornost se ocjenjivala i u bolesnika koji nisu podnosili imatinib.
The time to MMR is displayed graphically in Figure 1. 
Vrijeme do MMR grafički je prikazano na Slici 1.
Remind the patient or caregiver to shake the bottle vigorously prior to each use. 
Podsjetite bolesnika ili njegovatelja da mora snažno protresti bocu prije svake primjene.
CYP3A4 is a major enzyme responsible for the metabolism of dasatinib. 
CYP3A4 je glavni enzim za metabolizam dasatiniba.
If you have accidentally taken too many tablets, talk to your doctor immediately. 
Ako ste slučajno uzeli previše tableta, odmah se javite liječniku.
Time-to cCCyR Time-to MMR Durability of cCCyR 
Vrijeme do cCCyR Vrijeme do MMR Trajanje cCCyR
These 6 cases included cases of epiphyses delayed fusion, osteopaenia, growth retardation, and gynecomastia (see section 5.1). 
Tih 6 slučajeva uključivalo je slučajeve kasnog srastanja epifize, osteopenije, zastoja u rastu i ginekomastije (vidjeti dio 5.1).
Since dasatinib is associated with grade 3 or 4 myelosuppression (see section 4.4), patients who ingest more than the recommended dose should be closely monitored for myelosuppression and given appropriate supportive treatment. 
Budući da je dasatinib povezan s mijelosupresijom 3. ili 4. stupnja (vidjeti dio 4.4), bolesnici koji uzmu dozu veću od preporučene moraju biti strogo nadzirani zbog moguće mijelosupresije i primiti odgovarajuću potpornu terapiju.
Hypokalaemia or hypomagnesaemia should be corrected prior to dasatinib administration. 
Hipokalijemija ili hipomagnezijemija moraju se korigirati prije primjene dasatiniba.
Pregnant or breast-feeding women should avoid exposure to SPRYCEL powder for oral suspension. 
Trudnice i dojilje trebaju izbjegavati izlaganje SPRYCEL prašku za oralnu suspenziju.
Disease progression was defined as increasing white blood cells despite appropriate therapeutic management, loss of CHR, partial CyR or CCyR, progression to accelerated phase or blast phase, or death. 
Progresija bolesti bila je definirana kao povećanje broja bijelih krvnih stanica unatoč odgovarajućem terapijskom liječenju, gubitak CHR, djelomični CyR ili CCyR, napredovanje u ubrzanu fazu ili blastnu fazu ili smrt.
The film-coated tablets must not be crushed, cut or chewed in order to maintain dosing consistency and minimise the risk of dermal exposure; they must be swallowed whole. 
Filmom obložene tablete ne smiju se drobiti, rezati niti žvakati, kako bi se održala dosljednost doziranja i smanjio rizik dodira s kožom; moraju se progutati cijele.
Patients with mild, moderate or severe hepatic impairment may receive the recommended starting dose. 
Bolesnici s blagim, umjerenim ili teškim oštećenjem jetre mogu primiti preporučenu početnu dozu.
Make sure the second bottle is shaken before use. 
Obavezno protresite drugu bocu prije uporabe.
Histamine-2 antagonists and proton pump inhibitors 
Antagonisti histaminskih H2 receptora i inhibitori protonske pumpe
Since the renal clearance of dasatinib and its metabolites is < 4%, a decrease in total body clearance is not expected in patients with renal insufficiency. 
Budući da je bubrežni klirens dasatiniba i njegovih metabolita <4%, u bolesnika s bubrežnom insuficijencijom ne očekuje se smanjenje ukupnog klirensa iz tijela.
Thrombotic microangiopathy (TMA) 
Trombotska mikroangiopatija (TMA)
Thirty-eight percent of patients had baseline mutations known to confer imatinib resistance. 
Trideset i osam posto bolesnika imalo je osnovne mutacije za koje se zna da uzrokuju otpornost na imatinib.
Step 1: Tap bottom of each bottle (containing 33 g SPRYCEL powder for oral suspension) gently to loosen the powder. 
1. korak: Nježno lupnite dno svake boce (koja sadrži 33 g SPRYCEL praška za oralnu suspenziju) da bi se prašak rastresao.
Changes in the gastrointestinal, haematopoietic and lymphoid systems were reversible following cessation of treatment. 
Promjene u probavnom, hematopoetskom i limfnom sustavu bile su reverzibilne i povukle su se nakon prestanka liječenja.
Slowly withdraw the amount of SPRYCEL oral suspension prescribed by pulling the syringe plunger until it reaches the marking of the dose prescribed. 
Polako izvucite propisanu količinu SPRYCEL oralne suspenzije povlačenjem klipa štrcaljke do oznake koja označava propisanu dozu.
The MRD negativity rates at the end of induction and consolidation as measured by flow cytometry were 66.0% and 84.0%, respectively. 
Stopa negativnih nalaza na MRD na kraju indukcije i konsolidacije izmjerena protočnom citometrijom iznosila je 66,0% odnosno 84,0%.
Paediatric patients with CML 
Pedijatrijski bolesnici s KML