natgillin/translations-raw huggingface dataset:
The field studies showed that Equip WNV protects horses from West Nile virus by reducing the number of viraemic horses after infection with West Nile virus lineage 1 or 2 strains and by reducing the duration and severity of clinical signs against lineage 2 strains. 
Nila tako što smanjuje broj viremičnih konja nakon infekcije virusom Zapadnog Nila, linije sojeva 1 ili 2 te smanjuje trajanje i težinu kliničkih znakova linije sojeva 2.
How has Equip WNV been studied? 
Kako se Equip WNV ispitivao?
Blisters: 2 years. 
Blisteri: 2 godine.
Use within 100 days after opening. 
Iskoristiti unutar 100 dana od otvaranja.
Children and adolescents Nemdatine is not recommended for children and adolescents under the age of 18 years. 
Nemdatine se ne preporučuje za djecu i adolescente mlađe od 18 godina.
Continue to take Nemdatine as long as it is of benefit to you. 
Nastavite uzimati Nemdatine onoliko dugo koliko od nje imate koristi.
Nemdatine with food and drink 
Nemdatine s hranom i pićem
< 1/1,000), very rare (< 1/10,000), not known (cannot be estimated from the available data). 
1/1000), vrlo rijetko (< 1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
You may experience increased symptoms as described in section 4 ‘Possible side effects'. 
Mogli bi Vam se javiti izraženiji simptomi opisani u dijelu 4 „Moguće nuspojave“.
Some factors that may raise urine pH (see section 5.2 ‘Elimination') may necessitate careful monitoring of the patient. 
Neki čimbenici koji mogu povisiti pH mokraće (vidjeti dio 5.2 „Eliminacija”) mogu zahtijevati pažljivo nadziranje bolesnika.
If you go into hospital, let your doctor know that you are taking Nemdatine. 
Ako dođete u bolnicu, obavijestite svog liječnika da uzimate Nemdatine.
What Nemdatine looks like and contents of the pack 
Kako Nemdatine izgleda i sadržaj pakiranja
HDPE bottles: use within 100 days after opening. 
HDPE boce: iskoristiti unutar 100 dana od otvaranja.
What Nemdatine is and what it is used for 
Što je Nemdatine i za što se koristi
If you forget to take Nemdatine - If you find you have forgotten to take your dose of Nemdatine, wait and take your next dose at the usual time. 
Ako ste zaboravili uzeti Nemdatine - Ako ustanovite da ste zaboravili uzeti dozu lijeka Nemdatine, pričekajte i uzmite sljedeću dozu u uobičajeno vrijeme.
Talk to your doctor or pharmacist before taking Nemdatine - if you have a history of epileptic seizures - if you have recently experienced a myocardial infarction (heart attack), or if you are suffering from congestive heart failure or from an uncontrolled hypertension (high blood pressure). 
Obratite se svom liječniku ili ljekarniku prije nego uzmete Nemdatine - ako u anamnezi imate epileptičke napadaje - ako ste nedavno imali infarkt miokarda (srčani udar), ili ako bolujete od kongestivnog zatajenja srca ili nekontrolirane hipertenzije (povišeni krvni tlak).
Memantine has an absolute bioavailability of approximately 100 %. 
Apsorpcija Memantin ima apsolutnu bioraspoloživost od približno 100%.
Nemdatine should be administered orally once a day and should be taken at the same time every day. 
Nemdatine treba primjenjivati peroralno jedanput na dan i potrebno ga je uzimati svaki dan u isto vrijeme.
PVC/PVDC-Aluminium blisters. 
PVC/PVDC-aluminijski blisteri.
6.5 Nature and contents of container PVC/PVDC-Aluminium blisters. 
6.5 Vrsta i sadržaj spremnika PVC/PVDC-aluminijski blisteri.
- Concomitant use of memantine and amantadine should be avoided, owing to the risk of pharmacotoxic psychosis. 
Potrebno je izbjegavati istodobnu primjenu memantina i amantadina zbog rizika od farmakotoksične psihoze.
In the most extreme case of overdose, the patient survived the oral intake of a total of 2,000 mg memantine with effects on the central nervous system (coma for 10 days, and later diplopia and agitation). 
U najekstremnijem slučaju predoziranja bolesnik je preživio peroralno uzimanje ukupne količine od 2000 mg memantina s učincima na središnji živčani sustav (koma tijekom 10 dana, a nakon toga diplopija i agitacija).
Very Rare (affects less than 1 user in 10,000) - Seizures 
Vrlo rijetke (javljaju se kod manje od 1 na 10 000 korisnika) napadaji
Furthermore, Nemdatine has minor or moderate influence on the ability to drive and use machines such that outpatients should be warned to take special care. 
Nadalje, Nemdatine ima blagi ili umjereni utjecaj na sposobnost upravljanja vozilima i rada sa strojevima, pa ambulantne bolesnike treba upozoriti da na to obrate posebnu pozornost.
What Nemdatine is and what it is used for What you need to know before you take Nemdatine How to take Nemdatine 
Što je Nemdatine i za što se koristi Što morate znati prije nego počnete uzimati Nemdatine Kako uzimati Nemdatine
Also, Nemdatine may change your reactivity, making driving or operating machinery inappropriate. 
Nemdatine također može promijeniti Vašu sposobnost reagiranja, što čini upravljanje vozilima i rad na strojevima neprikladnima.
Other medicines and Nemdatine 
Drugi lijekovi i Nemdatine
What you need to know before you take Nemdatine 
Što morate znati prije nego počnete uzimati Nemdatine
In a study using orally administered 14C-memantine, a mean of 84 % of the dose was recovered within 20 days, more than 99 % being excreted renally. 
U ispitivanju u kojem je korišten oralno primijenjen 14C-memantin, uklonjeno je prosječno 84% doze unutar 20 dana, više od 99% izlučeno je putem bubrega.
QUALITATIVE AND QUANTITATIVE COMPOSITION Nemdatine 5 mg 
KVALITATIVNI I KVANTITATIVNI SASTAV Nemdatine 5 mg
Uncommon Confusion Uncommon Hallucinations1 
Manje često konfuzija Manje često halucinacije1
Adverse reactions are ranked according to system organ class, using the following convention: very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to 
Nuspojave su razvrstane prema klasifikaciji organskih sustava, koristeći sljedeću konvenciju: vrlo često (≥1/10), često (≥1/100 i < 1/10), manje često (≥ 1/1000 i < 1/100), rijetko (≥1/10 000 i <
INFORMATION IN BRAILLE Nemdatine 5 mg, 10 mg, 15 mg, 20 mg 
16. PODACI NA BRAILLEOVOM PISMU Nemdatine 5 mg, 10 mg, 15 mg, 20 mg
- Other active substances such as cimetidine, ranitidine, procainamide, quinidine, quinine and nicotine that use the same renal cationic transport system as amantadine may also possibly interact with memantine leading to a potential risk of increased plasma levels. 
Ostale djelatne tvari poput cimetidina, ranitidina, prokainamida, kinidina, kinina i nikotina koje koriste isti sustav bubrežnog kationskog transporta kao i amantadin mogle bi također stupiti u interakciju s memantinom i dovesti do potencijalnog rizika povišenja njegove koncentracije u plazmi.
Not known Pancreatitis2 
Nepoznato pankreatitis2
- In post-marketing experience, isolated cases with international normalized ratio (INR) increases have been reported in patients concomitantly treated with warfarin. 
U postmarketinškom iskustvu zabilježeni su izolirani slučajevi povišenja međunarodno ujednačenog omjera (INR-a) kod bolesnika koji su istodobno liječeni varfarinom.
Magnesium stearate 
A talk magnezijev stearat
The Nemdatine treatment initiation pack is only to be used for the beginning of the treatment with Nemdatine. 
Pakiranje lijeka Nemdatine za početak liječenja se treba koristiti samo na početku liječenja lijekom
- If you take a large overdose of Nemdatine, contact your doctor or get medical advice, as you may need medical attention. 
- Ako ste uzeli preveliku dozu lijeka Nemdatine, javite se Vašem liječniku za savjet, jer bi Vam mogla zatrebati medicinska pomoć.
In order to reduce the risk of undesirable effects, the maintenance dose is achieved by upward titration of 5 mg per week over the first 3 weeks as follows. 
Radi smanjenja rizika od nuspojava, doza održavanja se postiže titracijom povećavanjem doze od 5 mg tjedno tijekom prva 3 tjedna na sljedeći način.
Nemdatine belongs to a group of medicines known as anti-dementia medicines. 
Nemdatine se ubraja u skupinu lijekova poznatih kao lijekovi protiv demencije.
How to take Nemdatine 
Kako uzimati Nemdatine
The recommended maintenance dose is 20 mg once a day, which is reached at the beginning of the 4th week. 
Preporučena doza održavanja je 20 mg jedanput na dan, te se postiže na početku 4. tjedna.
Do not take Nemdatine - if you are allergic to memantine hydrochloride or any of the other ingredients of this medicine 
Nemojte uzimati Nemdatine - ako ste alergični na memantinklorid ili neki drugi sastojak ovog lijeka (naveden u dijelu 6).
Pharmacotherapeutic group: Psychoanaleptics, other Anti-dementia drugs, ATC code: N06DX01. 
Farmakoterapijska skupina: psihoanaleptici,ostali lijekovi protiv demencije, ATK oznaka: N06DX01.
Your doctor will tell you whether your illness allows you to drive and to use machines safely. 
Upravljanje vozilima i strojevima Liječnik će Vam reći dopušta li Vam bolest sigurno upravljanje vozilima i rad na strojevima.
Studies in volunteers have demonstrated linear pharmacokinetics in the dose range of 10 to 40 mg. Pharmacokinetic/pharmacodynamic relationship 
Ispitivanja na dobrovoljcima pokazala su linearnu farmakokinetiku u rasponu doza od 10 do 40 mg.
Balance disorders Uncommon Gait abnormal Very rare 
Manje često abnormalni hod Vrlo rijetko napadaji
In volunteers with normal kidney function, total clearance (Cltot) amounts to 170 ml/min/1.73 m² and part of total renal clearance is achieved by tubular secretion. 
Kod dobrovoljaca s normalnom funkcijom bubrega ukupni klirens (Cltot) iznosi do 170 ml/min/1,73 m², a dio se ukupnog bubrežnog klirensa postiže tubularnom sekrecijom.
The recommended treatment dose of 20 mg per day is achieved by a gradual increase of the Nemdatine dose during the first 3 weeks of treatment. 
Preporučena doza za liječenje od 20 mg dnevno postiže se postupnim povećanjem doze lijeka Nemdatine tijekom prva 3 tjedna liječenja.
In these situations the treatment should be carefully supervised, and the clinical benefit of Nemdatine reassessed by your doctor on a regular basis. 
U tim slučajevima liječenje mora biti pažljivo nadzirano, a liječnik treba redovito ponovno procjenjivati kliničku korist od uzimanja lijeka Nemdatine.
Not known (frequency cannot be estimated from the available data) - Inflammation of the pancreas, inflammation of the liver (hepatitis) and psychotic reactions 
Nepoznate učestalosti (učestalost se ne može procijeniti iz raspoloživih podataka) upala gušterače, upala jetre (hepatitis) i psihotične reakcije
When patients were identified with concurrent worsening in all three domains, results showed a statistically significant effect of memantine in preventing worsening, as twice as many placebo-treated patients as memantine-treated patients showed worsening in all three domains (21 % vs. 11 %, p < 0.0001). 
Kada je ustanovljeno istodobno pogoršanje stanja bolesnika u sva tri područja rezultati su pokazali statistički značajan učinak memantina u sprječavanju pogoršanja, u skupini bolesnika liječenih placebom bilo je dvostruko više pogoršanja u sva tri područja nego u skupini bolesnika liječenih memantinom (21% naspram 11%, p<0,0001).
- The other ingredients are: Tablet core: Microcrystalline cellulose, crospovidone Type A, talc and magnesium stearate. 
Drugi sastojci su: Jezgra tablete: mikrokristalična celuloza, krospovidon vrste A, talk i magnezijev stearat.
Nemdatine acts on these NMDA-receptors improving the transmission of nerve signals and the memory. 
Nemdatine djeluje na navedene NMDA receptore poboljšavajući prijenos živčanih signala i pamćenje.
The recommended dose of Nemdatine for adults and older people is 20 mg once a day. 
Preporučena doza lijeka Nemdatine za odrasle i starije osobe je 20 mg jedanput na dan.
At the beginning of treatment you will start by using Nemdatine 5 mg film-coated tablets once a day. 
Liječenje ćete započeti korištenjem Nemdatine filmom obloženih tableta od 5 mg jedanput na dan.
Treatment initiation pack. 
Pakiranje za početak liječenja.
The most frequently occurring adverse reactions with a higher incidence in the memantine group than in the placebo group were dizziness (6.3 % vs. 5.6 %, respectively), headache (5.2 % vs. 3.9 %), constipation (4.6 % vs. 2.6 %), somnolence (3.4 % vs. 2.2 %) and hypertension (4.1 % vs. 2.8 %). 
naspram 5,6%), glavobolja (5,2% naspram 3,9%), konstipacija (4,6% naspram 2,6%), somnolencija (3,4% naspram 2,2%) i hipertenzija (4,1% naspram 2,8%).
Day 15, 16, 17, 18, 19, 20, 21 
15., 16., 17., 18., 19., 20., 21. dan
HDPE bottle: 100 film-coated tablets. 
HDPE boca: 100 filmom obloženih tableta.
In patients with mildly impaired renal function (creatinine clearance 50 − 80 ml/min) no dose adjustment is required. 
Kod bolesnika s blagim oštećenjem funkcije bubrega (klirens kreatinina 50-80 ml/min) nije potrebna prilagodba doze.
Keep this medicine out of the sight and reach of children. 
Kako čuvati Nemdatine Ovaj lijek čuvajte izvan pogleda i dohvata djece.
Day 1, 2, 3, 4, 5, 6, 7 
1., 2., 3., 4., 5., 6., 7. dan
In particular, Nemdatine may change the effects of the following medicines and their dose may need to be adjusted by your doctor: - amantadine, ketamine, dextromethorphan - dantrolene, baclofen - cimetidine, ranitidine, procainamide, quinidine, quinine, nicotine - hydrochlorothiazide (or any combination with hydrochlorothiazide) - anticholinergics (substances generally used to treat movement disorders or intestinal cramps) - anticonvulsants (substances used to prevent and relieve seizures) - barbiturates (substances generally used to induce sleep) - dopaminergic agonists (substances such as L-dopa, bromocriptine) - neuroleptics (substances used in the treatment of mental disorders) - oral anticoagulants 
Posebice, Nemdatine može promijeniti učinak sljedećih lijekova te će liječnik možda morati prilagoditi njihovu dozu: - amantadin, ketamin, dekstrometorfan - dantrolen, baklofen - cimetidin, ranitidin, prokainamid, kinidin, kinin, nikotin - hidroklorotiazid (ili bilo koja kombinacija s hidroklorotiazidom)
Day 22, 23, 24, 25, 26, 27, 28 
4. tjedan 22., 23., 24., 25., 26., 27., 28. dan
Day 8, 9, 10, 11, 12, 13, 14 
8., 9., 10., 11., 12., 13., 14. dan
Blister packs: 28, 30, 42, 50, 56, 60, 98 and 112 film-coated tablets. 
Pakiranja s blisterima: 28, 30, 42, 50, 56, 60, 98 i 112 filmom obloženih tableta.
The usual starting dose is 5 mg memantine once a day for the first week. 
Uobičajena početna doza iznosi 5 mg memantina jedanput na dan tijekom prvog tjedna.
From the fourth week on, the usual dose is 20 mg memantine once a day. 
Od četvrtog tjedna nadalje, uobičajena doza je 20 mg memantina jedanput na dan.
Uncommon (affects 1 to 10 users in 1,000) - Tiredness, fungal infections, confusion, hallucinations, vomiting, abnormal gait, heart failure and venous blood clotting (thrombosis/thromboembolism) 
Manje česte (javljaju se kod 1 do 10 na 1000 korisnika) umor, gljivične infekcije, smetenost, halucinacije, povraćanje, poremećaj hoda, zatajenje srca i zgrušavanje venske krvi (tromboza/tromboembolija)
- The other ingredients for Nemdatine 5, 10, 15 and 20 mg film-coated tablets are: Tablet core: Microcrystalline cellulose, crospovidone Type A, talc and magnesium stearate. 
- Drugi sastojci za Nemdatine 5, 10, 15 i 20 mg filmom obložene tablete su: Jezgra tablete: mikrokristalična celuloza, krospovidon vrste A, talk i magnezijev stearat.
The recommended starting dose is 5 mg per day which is stepwise increased over the first 4 weeks of treatment reaching the recommended maintenance dose as follows: Week 1 (day 1-7): 
Preporučena početna doza je 5 mg dnevno, koja se postupno povećava tijekom prva 4 tjedna liječenja, te doseže preporučenu dozu održavanja na sljedeći način:
Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. 
potpunim nedostatkom laktaze ili malapsorpcijom glukoze i galaktoze ne bi smjeli uzimati ovaj lijek.
engraved on one side. 
„M20” na jednoj strani.
The following Adverse Reactions listed in the table below have been accumulated in clinical studies with memantine and since its introduction in the market. 
Tablični popis nuspojava Sljedeće nuspojave koje su prikupljene tijekom kliničkih ispitivanja s memantinom i nakon stavljanja lijeka u promet su prikazane u tablici ispod.
This is increased to 10 mg memantine in the second week and to 15 mg memantine once a day in the third week. 
Ova doza se povećava na 10 mg memantina u drugom tjednu, te na 15 mg memantina jedanput na dan u trećem tjednu.
Bottle: 100 film-coated tablets. 
Boca: 100 filmom obloženih tableta.
Nemdatine contains lactose monohydrate 
Nemdatine sadrži laktozu hidrat
What Nemdatine contains - The active substance is memantine hydrochloride. 
Što Nemdatine sadrži - Djelatna tvar je memantinklorid.
One treatment initiation pack contains 28 tablets in 4 blisters in a wallet pack or a multipack of 4 blisters in 4 separate immediate cartons and one outer carton with 7 tablets of Nemdatine 5 mg, 7 tablets of Nemdatine 10 mg, 7 tablets of Nemdatine 15 mg and 7 tablets of Nemdatine 20 mg. 
Jedno pakiranje za početak liječenja sadrži 28 tableta u 4 blistera u preklopnom pakiranju ili višestruko pakiranje od 4 blistera u 4 unutarnje kutije i jednoj vanjskoj kutiji sa 7 tableta od Nemdatine 5 mg, 7 tableta od Nemdatine 10 mg, 7 tableta od Nemdatine 15 mg i 7 tableta od Nemdatine 20 mg.
28 film-coated tablets 30 film-coated tablets 42 film-coated tablets 50 film-coated tablets 56 film-coated tablets 60 film-coated tablets 98 film-coated tablets 112 film-coated tablets 
28 filmom obloženih tableta 30 filmom obloženih tableta 42 filmom obložene tablete 50 filmom obloženih tableta 56 filmom obloženih tableta 60 filmom obloženih tableta 98 filmom obloženih tableta 112 filmom obloženih tableta
Additional for 15 mg film-coated tablets Iron oxide yellow, red and black (E172) Additional for 20 mg film-coated tablets Iron oxide red and yellow (E172) 
Dodatno kod 15 mg filmom obloženih tableta željezov oksid, žuti, crveni i crni (E172) Dodatno kod 20 mg filmom obloženih tableta željezov oksid, crveni i žuti (E172) 6.2 Inkompatibilnosti
Do not use this medicine after the expiry date which is stated on the carton and blister after ‘EXP'. 
Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i blisteru iza oznake „EXP“.
What is Nemdatine used for Nemdatine is used for the treatment of adult patients with moderate to severe Alzheimer's disease. 
Nemdatine se koristi za liječenje odraslih bolesnika s umjerenom do teškom Alzheimerovom bolešću.
CONDITIONS OR RESTRICTIONS REGARDING SUPPLY AND USE Medicinal product subject to restricted prescription (see Annex I: Summary of Product Characteristics, section 4.2). 
Lijek se izdaje na ograničeni recept (vidjeti Prilog I.: Sažetak opisa svojstava lijeka, dio 4.2.).
Do not use this medicine after the expiry date which is stated on the carton, blister and bottle label after ‘EXP'. 
Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na pakiranju, blisteru i naljepnici na boci iza „EXP“.
Each pack contains 28 film-coated tablets (7 film-coated tablets of 5 mg, 7 film-coated tablets of 10 mg, 7 film-coated tablets of 15 mg and 7 film-coated tablets of 20 mg) in a wallet pack or as a pack of 4 blisters in 4 separate immediate cartons and one outer carton. 
Jedno pakiranje sadrži 28 filmom obloženih tableta (7 filmom obloženih tableta od 5 mg, 7 filmom obloženih tableta od 10 mg, 7 filmom obloženih tableta od 15 mg i 7 filmom obloženih tableta od 20 mg) u preklopnom pakiranju ili višestrukom pakiranju od 4 blistera u 4 unutarnje kutije i jednoj vanjskoj kutiji.
How does Nemdatine work 
Kako djeluje Nemdatine
Each tablet contains 5, 10, 15 or 20 mg of memantine hydrochloride equivalent to 4.15, 8.31, 12.46 or 16.62 mg memantine. 
Jedna tableta sadrži 5, 10, 15 ili 20 mg memantinklorida, što odgovara 4,15; 8,31; 12,46 ili 16,62 mg memantina.
The 20 mg tablets furthermore contain iron oxide red and yellow (E172). 
Osim toga, tablete od 20 mg sadrže željezov oksid, crveni i žuti (E172).
Nemdatine should be administered orally once a day. 
Nemdatine treba primjenjivati kroz usta jedanput na dan.
This medicinal product contains lactose. 
Ovaj lijek sadrži laktozu hidrat.
Memantine-treated patients showed a statistically significantly better effect than placebo-treated patients on the primary endpoints: Alzheimer´s disease assessment scale (ADAS-cog) (p = 0.003) and CIBIC-plus (p = 0.004) at week 24 (last observation carried forward (LOCF)). 
Bolesnici liječeni memantinom pokazali su statistički značajno bolji učinak nego bolesnici koji su primali placebo u pogledu primarnih ishoda: skala procjene Alzheimerove bolesti (ADAS-cog) (p=0,003) i CIBIC-plus
- The mode of action suggests that the effects of L-dopa, dopaminergic agonists, and anticholinergics may be enhanced by concomitant treatment with NMDA-antagonists such as memantine. 
Zbog farmakoloških učinaka i mehanizma djelovanja memantina moguće su sljedeće interakcije: Način djelovanja sugerira da bi učinci L-dope, dopaminergičkih agonista i antikolinergika mogli biti pojačani pri istodobnom liječenju NMDA-antagonistima poput memantina.
In this case, monitoring of your kidney function should be performed by your doctor at specified intervals. 
U tom slučaju liječnik treba u određenim razmacima nadzirati funkciju bubrega.
The 15 mg tablets furthermore contain iron oxide yellow, red and black (E172). 
Osim toga, tablete od 15 mg sadrže željezov oksid, žuti, crveni i crni (E172).
PARTICULARS TO APPEAR ON THE OUTER PACKAGING. 
PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU
Nemdatine contains the active substance memantine hydrochloride. 
Nemdatine sadrži djelatnu tvar memantinklorid.
Week 2 (day 8-14): Take one 10 mg tablet once a day (white, capsule shaped) for 7 days. 
2. tjedan (8. - 14. dan): Uzimajte jednu tabletu od 10 mg jedanput na dan (bijelu, u obliku kapsule) tijekom 7 dana.
This is increased to two tablets once a day (1x 10 mg) in the second week and to three tablets once a day (1x 15 mg) in the third week. 
Ova doza se povećava na dvije tablete jedanput na dan (1x 10 mg) u drugom tjednu, te na tri tablete jedanput na dan (1x 15 mg) u trećem tjednu.
Nemdatine belongs to a group of medicines called NMDAreceptor antagonists. 
Nemdatine spada u skupinu lijekova poznatih kao antagonisti NMDA
If you take more Nemdatine than you should - In general, taking too much Nemdatine should not result in any harm to you. 
- Općenito, uzimanje previše lijeka Nemdatine ne bi Vam trebalo naškoditi.
From the fourth week on, the usual dose is 4 tablets once a day (1x 20 mg). 
Od četvrtog tjedna nadalje, uobičajena doza je 4 tablete jedanput na dan (1x 20 mg).
On the basis of the clinical studies, the recommended dose for patients over the age of 65 years is 20 mg per day (20 mg once a day) as described above. 
Temeljem kliničkih ispitivanja, preporučena doza za bolesnike starije od 65 godina iznosi 20 mg dnevno
Common (affects 1 to 10 users in 100) - Headache, sleepiness, constipation, elevated liver function test, dizziness, balance disorders, 
Česte (javljaju se kod 1 do 10 na 100 korisnika) glavobolja, pospanost, zatvor, povišeni rezultati testova jetrene funkcije, omaglica, poremećaji ravnoteže, nedostatak zraka, visoki krvni tlak i preosjetljivost na lijek
The patient should take four 5 mg film-coated tablets (20 mg), two 10 mg film-coated tablets (20 mg) or one 20 mg film-coated tablet (20 mg) per day. 
Bolesnik treba uzimati četiri filmom obložene tablete od 5 mg (20 mg), dvije filmom obložene tablete od 10 mg (20 mg) ili jednu filmom obloženu tabletu od 20 mg (20 mg) dnevno.
Tablet cores for 5, 10, 15 and 20 mg film-coated tablets Microcrystalline cellulose 
Jezgra tablete za 5, 10, 15 i 20 mg filmom obložene tablete celuloza, mikrokristalična krospovidon vrste
From the fourth week on, the usual dose is 2 tablets once a day (1x 20 mg). 
Od četvrtog tjedna nadalje, uobičajena doza je 2 tablete jedanput na dan (1x 20 mg).
Week 3 (day 15-21): Take one 15 mg tablet once a day (orange, oval shaped) for 7 days. 
3. tjedan (15. - 21. dan): Uzimajte jednu tabletu od 15 mg jedanput na dan (narančastu, ovalnog oblika) tijekom 7 dana.