natgillin/translations-raw huggingface dataset:
If treatment with an HMG-CoA reductase inhibitor is indicated, pravastatin or fluvastatin is recommended. 
Ako je indicirano liječenje inhibitorom HMG-CoA reduktaze, preporučuje se pravastatin ili fluvastatin.
Very common Abdominal pain (upper and lower), nausea, diarrhoea (including severe with electrolyte imbalance), vomiting, dyspepsia 
Vrlo često Bol u gornjem i donjem abdomenu, mučnina, proljev (uključujući teški proljev s elektrolitskim disbalansom), povraćanje,
For details on preparation and administration of Norvir powder for oral suspension, refer the patient or care giver to the Package Leaflet, section 3. 
Za pojedinosti o pripremi i primjeni Norvir praška za oralnu suspenziju uputiti bolesnika ili njegovatelja da pogledaju dio 3 Upute o lijeku.
0.5 single IV dose 300 q12h, 3 days 
0,5 jednokratne iv. doze 300 svakih 12h, 3 dana
Concentrations of colchicine are expected to increase when coadministered with ritonavir. 
Očekuju se povećane koncentracije kolhicina pri istodobnoj primjeni s ritonavirom.
Caution should be exercised in administering afatinib with Norvir (refer to the afatinib SmPC). 
Potreban je oprez kada se afatinib primjenjuje zajedno s lijekom Norvir (vidjeti Sažetak opisa svojstava lijeka za afatinib).
Apalutamide is a moderate to strong CYP3A4 inducer and this may lead to a decreased exposure of ritonavir and potential loss of virologic response. 
Apalutamid je umjeren do snažan induktor CYP3A4 što može dovesti do smanjene izloženosti ritonaviru i potencijalnog gubitka virološkog odgovora.
− clorazepate, diazepam, estazolam, flurazepam, triazolam or oral (taken by mouth) midazolam (used to help you sleep and/or relieve anxiety); 
− klorazepat, diazepam, estazolam, flurazepam, triazolam ili oralni (uzet kroz usta) midazolam (koristi se za spavanje i/ili ublažavanje tjeskobe);
Stevens Johnson syndrome, toxic epidermal necrolysis (TEN) 
Rijetko Stevens-Johnsonov sindrom, toksična epidermalna nekroliza (TEN)
Clozapine, pimozide Increased plasma concentrations of clozapine and pimozide. 
Klozapin, pimozid Povećane koncentracije klozapina i pimozida u plazmi.
Very common Pharyngitis, oropharyngeal pain, cough 
Vrlo često Faringitis, orofaringalna bol, kašalj
• Discard any mixture remaining in the mixing cup. 
• Bacite sve što je ostalo u čaši za miješanje.
Tissue to plasma ratios of approximately 1 measured in rat lymph nodes suggests that ritonavir distributes into lymphatic tissues. 
Omjer tkivo:plazma od oko 1, izmjeren u limfnim čvorovima štakora, upućuje na to da se ritonavir distribuira u limfna tkiva.
AbbVie Deutschland GmbH & Co. KG, Knollstrasse, 67061 Ludwigshafen, Germany AbbVie Logistics B.V., Zuiderzeelaan 53, 8017 JV Zwolle, The Netherlands 
KG, Knollstrasse, 67061 Ludwigshafen, Njemačka AbbVie Logistics B.V.,Zuiderzeelaan 53, 8017 JV Zwolle, Nizozemska
The recommended dose of Norvir film-coated tablets is 600 mg (6 tablets) twice daily (total of 1200 mg per day) by mouth. 
Preporučena doza Norvir filmom obloženih tableta je 600 mg (šest tableta) dva puta na dan kroz usta (ukupno 1200 mg na dan).
Pharmacotherapeutic group: antivirals for systemic use, protease inhibitors ATC code: J05AE03 
Farmakoterapijska skupina: antivirotici za sistemnu primjenu, inhibitori proteaza ATK oznaka: J05AE03
• Use the provided oral dosing syringe to measure and administer the prescribed ml volume (see section 4.2). 
• Koristite priloženu dozirnu štrcaljku za usta kako biste izmjerili i primijenili propisani volumen u mililitrima (vidjeti dio 4.2).
Recommendations regarding use of ritonavir dosed as a pharmacokinetic enhancer with rifabutin are noted in section 4.5. 
Preporuke o primjeni ritonavira kada se dozira kao farmakokinetički pojačivač u kombinaciji s rifabutinom navedene su u dijelu 4.5.
Theophylline1 
Teofilin1
− antibiotics (e.g. erythromycin, clarithromycin); 
− antibiotike (npr. eritromicin, klaritromicin);
Amprenavir ↑ 2.4 fold ↑ 11 fold 
Amprenavir ↑ 2,4 puta ↑ 11 puta
Amphetamine Derivatives 
Derivati amfetamina
Medicinal Product Interactions - Ritonavir with Protease Inhibitors 
Interakcije lijekova - ritonavir s inhibitorima proteaza
Endothelin antagonists 
Antagonisti endotelinskih receptora
438 mg (43.8 ml) twice daily 
438 mg (43,8 ml) dva puta na dan
Nevirapine Ritonavir Co-administration of ritonavir with nevirapine does not lead to clinically relevant changes in the pharmacokinetics of either nevirapine or ritonavir. 
Primjena ritonavira istodobno s nevirapinom ne uzrokuje klinički značajne promjene farmakokinetike ni nevirapina ni ritonavira.
If trazodone is coadministered with ritonavir, the combination should be used with caution, initiating trazodone at the lowest dosage and monitoring for clinical response and tolerability. 
Ako se trazodon daje istodobno s ritonavirom, tu kombinaciju treba davati oprezno, a trazodon treba početi davati u najmanjoj dozi te pratiti klinički odgovor i podnošljivost.
The time to maximum concentration (Tmax) remained constant at approximately 4 hours with increasing dose. 
(Tmax) ostalo je nepromijenjeno, na otprilike 4 sata, pri primjeni rastućih doza.
Ritonavir concentrations obtained after 350 to 400 mg/m² twice daily in paediatric patients were comparable to those obtained in adults receiving 600 mg (approximately 330 mg/m²) twice daily. 
Koncentracije ritonavira izmjerene nakon primjene doza od 350 do 400 mg/m2 dva puta na dan pedijatrijskim bolesnicima bile su usporedive s onima izmjerenima u odraslih koji su uzimali 600 mg (oko 330 mg/m2) dva puta na dan.
Co-administration of bosentan and ritonavir may increase steady state bosentan maximum concentrations (Cmax) and area under the curve (AUC) 
Istodobna primjena bosentana i ritonavira može povećati maksimalne koncentracije bosentana u stanju dinamičke ravnoteže (Cmax) i površinu ispod krivulje (AUC)
declined with age with median values of 9.0 L/h/m2 in children less than 3 months of age, 7.8 L/h/m2 in children between 3 and 6 months of age and 4.4 L/h/m2 in children between 6 and 24 months of age. 
smanjivao s dobi, te su medijani vrijednosti iznosili 9,0 l/h/m2 u djece mlađe od 3 mjeseca, 7,8 l/h/m2 u djece u dobi od 3 do 6 mjeseci, a 4,4 l/h/m2 u djece u dobi od 6 do 24 mjeseca.
- Steroids (e.g. dexamethasone, fluticasone propionate, prednisolone, triamcinolone) as Norvir may raise the blood levels of these medicines which may lead to Cushing's syndrome (development of a rounded face) and reduce production of the hormone cortisol. 
− Steroidi (npr. deksametazon, flutikazonpropionat, prednizolon, triamcinolon), jer Norvir može povisiti razine tih lijekova u krvi, što može izazvati pojavu Cushingova sindroma (stvaranje okruglog lica) i smanjiti stvaranje hormona kortizola.
Sleeping agent 
Sredstva za spavanje
− antiretroviral medicines including HIV-protease inhibitors (amprenavir, atazanavir, darunavir, 
− antiretrovirusne lijekove, uključujući inhibitore HIV-proteaza (amprenavir, atazanavir,
− sleeping pills (e.g. alprazolam, zolpidem) and also midazolam administered by injection; 
− pilule za spavanje (npr. alprazolam, zolpidem) i midazolam u injekcijama;
A dose reduction of the glucocorticoid should be considered with close monitoring of local and systemic effects or a switch to a glucocorticoid, which is not a substrate for CYP3A4 (e.g., beclomethasone). 
Valja razmotriti smanjivanje doze glukokortikoida i pažljivo pratiti lokalne i sistemne učinke, ili prijeći na primjenu glukokortikoida koji nije supstrat enzima CYP3A4 (npr.
Common Hypersensitivity, including urticaria and face oedema. 
Često Preosjetljivost, uključujući urtikariju i edem lica.
− anticoagulants (e.g. rivaroxaban, vorapaxar, warfarin); 
− antikoagulanse (npr. rivaroksaban, vorapaksar, varfarin);
Therefore, Norvir should not be co-administered with orally administered midazolam (see section 4.3), whereas caution should be used with co-administration of Norvir and parenteral midazolam. 
Stoga se Norvir ne smije davati istodobno s midazolamom koji se uzima oralno (vidjeti dio 4.3), a pri korištenju lijeka Norvir istodobno s midazolamom za parenteralnu primjenu nužan je oprez.
Tablet: 
tableta)
Powder for oral suspension dose 
Doza praška za oralnu suspenziju
(For caution on parenterally administered midazolam, see section 4.5). 
(Za mjere opreza pri parenteralnoj primjeni midazolama vidjeti dio 4.5).
− voriconazole (used to treat fungal infections)*; 
− vorikonazol (koristi se za liječenje gljivičnih infekcija)*;
Ritonavir film-coated tablets are administered orally and should be ingested with food (see section 
Ritonavir filmom obložene tablete primjenjuju se oralno i preporučuje se uzimanje s hranom (vidjeti dio 5.2).
- Kidney (renal) disease, since your doctor may need to check the dose of your other medicines (such as protease inhibitors). 
− Bolest bubrega, jer će Vaš liječnik možda trebati provjeriti doze drugih lijekova koje uzimate (npr. inhibitori proteaza).
Ergot Derivatives 
Derivati ergota
In cases of co-administration of ritonavir (100 mg twice daily) and indinavir (800 mg twice daily) caution is warranted as the risk of nephrolithiasis may be increased. 
slučajevima istodobne primjene ritonavira (100 mg dva puta na dan) i indinavira (800 mg dva puta na dan) savjetuje se oprez jer zbog povećanog rizika od nefrolitijaze.
Serum concentrations may be increased when co-administered with ritonavir which may increase the risk of toxicity, including the risk of serious adverse events such as QT interval prolongation. 
Serumske se koncentracije mogu povećati pri istodobnoj primjeni ritonavira što može povećati rizik od toksičnosti, uključujući rizik od ozbiljnih štetnih događaja kao što je produljenje QT intervala.
MINIMUM PARTICULARS TO APPEAR ON SMALL PACKAGING UNITS NORVIR POWDER FOR ORAL SUSPENSION - Sachet Label Text 
PODACI KOJE MORA NAJMANJE SADRŽAVATI MALO UNUTARNJE PAKIRANJE NORVIR PRAŠAK ZA ORALNU SUSPENZIJU - Tekst na naljepnici vrećice
Lovastatin, simvastatin Increased plasma concentrations of lovastatin and simvastatin; thereby, increasing the risk of myopathy including rhabdomyolysis (see section 
Lovastatin, simvastatin Povećane koncentracije lovastatina i simvastatina u plazmi; time se povećava rizik od miopatije, uključujući rabdomiolizu (vidjeti dio 4.5).
- If Norvir is taken in combination with other antiretroviral medicines, it is important that you also carefully read the leaflets that are provided with these other medicines. 
− Ako Norvir uzimate u kombinaciji s drugim antiretrovirusnim lijekovima, važno je da pažljivo pročitate i upute o lijeku priložene tim drugim lijekovima.
Data from concomitant use of parenteral midazolam with other protease inhibitors suggest a possible 3 - 4 fold increase in midazolam plasma levels. 
Podaci o istodobnoj primjeri parenteralnog midazolama s drugim inhibitorima proteaza upućuju na to da se razine midazolama u plazmi mogu povećati 3-4 puta.
Alpha1-Adrenoreceptor Antagonist 
Antagonist alfa1-adrenoreceptora
Step 8. 
Korak 8.
− bupropion, a medicine used to help you stop smoking; 
− bupropion, koji se koristi za odvikavanje od pušenja;
Concomitant administration of Norvir and quetiapine is contraindicated as it may increase quetiapine-related toxicity (see section 4.3). 
Istodobna primjena lijeka Norvir i kvetiapina je kontraindicirana jer može povećati s kvetiapinom povezanu toksičnost (vidjeti dio 4.3).
− anticancer treatments (e.g. abemaciclib; afatinib, apalutamide, ceritinib, encorafenib, dasatinib, 
− lijekove za rak (npr. abemaciklib, afatinib, apalutamid, ceritinib, enkorafenib, dasatinib,
PARTICULARS TO APPEAR ON THE OUTER PACKAGING NORVIR POWDER FOR ORAL SUSPENSION - Carton containing 30 sachets each containing 100mg ritonavir 
PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU NORVIR PRAŠAK ZA ORALNU SUSPENZIJU - Kutija koja sadrži 30 vrećica od kojih svaka sadrži 100 mg ritonavira
Fosamprenavir 700 q12h 
Fosamprenavir 700 svakih 12h
Dasatinib, nilotinib, vincristine, vinblastine Serum concentrations may be increased when co-administered with ritonavir resulting in the potential for increased incidence of adverse events. 
Dasatinib, nilotinib, vinkristin, vinblastin Serumske se koncentracije mogu povećati pri istodobnoj primjeni ritonavira, zbog čega se može povećati učestalost štetnih događaja.
200 q8h ↑ 77% 
200 svakih 8h ↑ 77%
Didanosine As ritonavir is recommended to be taken with food and didanosine should be taken on an empty stomach, dosing should be separated by 2.5 h. Dose alterations should not be necessary. 
Budući da se preporučuje uzimanje ritonavira s hranom, a didanozin se mora uzimati na prazan želudac, između uzimanja dvaju lijekova treba načiniti razmak od 2,5 sata.
• Let the liquid stand for 10 minutes in order for most of the bubbles to disappear. 
• Pustite otopinu da odstoji 10 minuta kako bi nestali mjehurići.
In a clinical study investigating the interaction of rifampicin 600 mg once daily and saquinavir 1000 mg with ritonavir 100 mg twice daily in healthy volunteers, severe hepatocellular toxicity with transaminase elevations up to > 20-fold the upper limit of normal after 1 to 5 days of co-administration was noted. 
U kliničkom ispitivanju interakcija rifampicina 600 mg jedanput na dan i sakvinavira 1000 mg s ritonavirom 100 mg dva puta na dan u zdravih dobrovoljaca uočena je hepatocelularna toksičnost s porastom vrijednosti transaminaza do >20 puta iznad gornje granice normale nakon 1-5 dana od početka istodobne primjene.
Fusidic Acid 
Fuzidična kiselina
Very common Dysgeusia, oral and peripheral paraesthesia, headache, dizziness, peripheral neuropathy 
Vrlo često Disgeuzija, cirkumoralna i periferna parestezija, omaglica, periferna neuropatija
b. Place the syringe tip at the bottom of the mixing cup. 
Stavite vrh štrcaljke na dno čaše za miješanje.
Caution should be exercised in administering ceritinib with Norvir. 
Potreban je oprez kada se ceritinib primjenjuje zajedno s lijekom Norvir.
Patients who exhibit these signs or symptoms should be evaluated and Norvir therapy should be discontinued if a diagnosis of pancreatitis is made (see section 4.8). 
Bolesnike u kojih se jave ti znaci ili simptomi treba obraditi, a ako se postavi dijagnoza pankreatitisa, liječenje lijekom Norvir treba obustaviti (vidjeti dio 4.8).
Amphetamine 
Amfetamin
Common Hypercholesterolaemia, hypertriglyceridaemia, gout, oedema and peripheral oedema, dehydration (usually associated with gastrointestinal symptoms) 
Često Hiperkolesterolemija, hipertrigliceridemija, giht, edem i periferni edem, dehidracija (uglavnom povezana sa simptomima od strane probavnog sustava)
Thyroid hormone replacement therapy 
Nadomjesna terapija tireoidnog hormona
Adverse reactions from clinical trials and post-marketing experience in adult patients The most frequently reported adverse drug reactions among patients receiving ritonavir alone or in combination with other antiretroviral drugs were gastrointestinal (including diarrhea, nausea, vomiting, abdominal pain (upper and lower)), neurological disturbances (including paresthesia and oral paresthesia) and fatigue/asthenia. 
Nuspojave iz kliničkih ispitivanja i iz postmarketinškog praćenja kod odraslih bolesnika Najčešće zabilježene nuspojave među bolesnicima koji su uzimali ritonavir sam ili u kombinaciji s drugim antiretrovirusnim lijekovima bili su poremećaji probavnog sustava (uključujući proljev, mučninu, povraćanje, bol u gornjem i donjem abdomenu, neurološki poremećaji (uključujući paresteziju i oralnu paresteziju) i umor/astenija.
fosamprenavir, indinavir, nelfinavir, saquinavir, tipranavir), non-nucleoside reverse transcriptase inhibitors (NNRTI) (delavirdine, efavirenz, nevirapine), and others (didanosine, maraviroc, 
darunavir, fosamprenavir, indinavir, nelfinavir, sakvinavir, tipranavir), nenukleozidne inhibitore reverzne transkriptaze (delavirdin, efavirenz, nevirapin) i druge (didanozin, maravirok, raltegravir, zidovudin);
− epilepsy medicines (e.g. carbamazepine, divalproex, lamotrigine, phenytoin); 
− lijekove za epilepsiju (npr. karbamazepin, divalproeks, lamotrigin, fenitoin);
− ranolazine (used to treat chronic chest pain [angina]); 
− ranolazin (lijek za liječenje kronične boli u prsištu [angine]);
nortriptyline, paroxetine, sertraline, trazodone); 
paroksetin, sertralin, trazodon);
In contrast to long-term administration of ritonavir, there was no significant interaction with bupropion after short-term administration of low doses of ritonavir (200 mg twice daily for 2 days), suggesting reductions in bupropion concentrations may have onset several days after initiation of ritonavir co-administration. 
Za razliku od dugotrajne primjene ritonavira, nije bilo značajne interakcije s bupropionom pri kratkotrajnoj primjeni ritonavira u malim dozama (200 mg dva puta na dan tijekom 2 dana), što upućuje na to da se koncentracije bupropiona počinju smanjivati nekoliko dana nakon uvođenja ritonavira.
- Diabetes, as there have been reports of worsening of or the development of diabetes (diabetes mellitus) in some patients taking protease inhibitors. 
− Šećernu bolest, jer je bilo prijava pogoršanja ili razvoja šećerne bolesti (dijabetes melitus) u nekih bolesnika koji su uzimali inhibitore proteaza.
Taking Norvir with food and drink 
Uzimanje hrane i pića s lijekom Norvir
− Haemophilia, as there have been reports of increased bleeding in patients with haemophilia who are taking this type of medicine (protease inhibitors). 
− Hemofiliju, jer je bilo prijava pojačanog krvarenja u bolesnika s hemofilijom koji uzimaju ovu vrstu lijekova (inhibitore proteaza).
− lomitapide (used to lower blood cholesterol); 
− lomitapid (koristi se za snižavanje kolesterola u krvi);
- Hepatitis B or C and are being treated with a combination of antiretroviral agents, as you are at a greater risk of a severe and potentially life threatening reaction because of the effect on the liver. 
− Hepatitis B ili C i liječite se kombinacijom antiretrovirusnih lijekova, jer ste izloženi većem riziku od teške i možda za život opasne reakcije zbog učinka na jetru.
− tranquillisers (e.g. haloperidol, risperidone, thioridazine); 
− trankvilizatore (npr. haloperidol, risperidon, tioridazin);
HCV Protease Inhibitor 
Inhibitori proteaze HCV-a
The mean average change from baseline over 48 weeks for HIV RNA levels was -0.88 log10 in the ritonavir group versus -0.66 log10 in the ritonavir + zidovudine group versus -0.42 log10 in the zidovudine group. 
Srednja prosječna promjena razine HIV RNK nakon 48 tjedana u odnosu na početno stanje iznosila je -0,88 log10 u skupine liječene ritonavirom i -0,66 log10 u skupine koja je primala ritonavir + zidovudin, a -0,42 log10 u skupine koja je primala samo zidovudin.
The mean average change from baseline over 16 weeks for HIV RNA levels was -0.79 log10 (maximum mean decrease: 1.29 log10) in the ritonavir group versus -0.01 log10 in the control group. 
Srednja prosječna promjena razina HIV RNK nakon 16 tjedana u odnosu na početno stanje iznosila je -0,79 log10 (maksimalno srednje smanjenje: 1,29 log10) u skupini liječenoj ritonavirom, u usporedbi s -0.01 log10 u kontrolnoj skupini.
The bitter aftertaste of Norvir powder for oral suspension may be lessened if peanut butter, hazelnut chocolate spread, or black currant syrup are taken immediately after dose administration. 
Gorak okus u ustima nakon primjene Norvir praška za oralnu suspenziju se može ublažiti ako se odmah nakon primjene doze uzmu maslac od kikirikija, namaz od lješnjaka i čokolade ili sirup od crnog ribiza.
Saquinavir/ritonavir should not be given together with rifampicin, due to the risk of severe hepatotoxicity (presenting as increased hepatic transaminases) if the three medicines are given together (see section 4.5). 
Sakvinavir/ritonavir ne smiju se davati istodobno s rifampicinom zbog rizika od teške hepatotoksičnosti (koja se očituje porastom vrijednosti jetrenih transaminaza) ako se ta tri lijeka daju istodobno (vidjeti dio 4.5).
Tissue distribution studies with 14C-labelled ritonavir in rats showed the liver, adrenals, pancreas, kidneys and thyroid to have the highest concentrations of ritonavir. 
Ispitivanja distribucije 14C-obilježenog ritonavira po tkivima štakora pokazala su najviše koncentracije ritonavira u jetri, nadbubrežnim žlijezdama, gušterači, bubrezima i štitnjači.
β2-agonist (long acting) 
β2-agonist (dugodjelujući) Salmeterol
− immune system (e.g. cyclosporine, tacrolimus, everolimus); 
− imunosupresive (npr. ciklosporin, takrolimus, everolimus);
SPECIAL STORAGE CONDITIONS Store in the original bottle in order to protect from moisture. 
POSEBNE MJERE ČUVANJA Čuvati u originalnoj boci, radi zaštite od vlage.
Concomitant use of neratinib with Norvir is contraindicated due to serious and/or life-threatening potential reactions including hepatotoxicity (see section 4.3). 
Istodobna primjena neratiniba i lijeka Norvir je kontraindicirana zbog ozbiljnih i/ili po život opasnih mogućih reakcija, uključujući hepatotoksičnost (vidjeti dio 4.3).
Do not use Norvir powder for oral suspension after the expiry date on the sachet and carton. 
Norvir prašak za oralnu suspenziju se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na vrećici i kutiji.
Administration of a single 100 mg dose of Norvir tablet with a moderate fat meal (857 kcal, 31% calories from fat) or a high fat meal (907 kcal, 52% calories from fat) was associated with a mean decrease of 20-23% in ritonavir AUC and Cmax. 
Primjena jednokratne doze od 100 mg Norvir tablete s umjereno masnom hranom (857 kcal, 31% kalorija iz masnoća) i hranom s visokim sadržajem masti (907 kcal, 52% kalorija iz masnoća) bila je povezana s srednjim smanjenjem AUC i Cmax ritonavira za 20%-23%.
Ritonavir is not a cure for HIV-1 infection or AIDS. 
Ritonavir nije lijek za izlječenje infekcije virusom HIV-1 ni AIDS-a.
The safety and efficacy of Norvir in children aged below 2 years has not been established. 
Pedijatrijska populacija Sigurnost i djelotvornost lijeka Norvir u djece u dobi manjoj od 2 godine nisu još ustanovljene.
Saquinavir4 ↑ 17-fold ND 
Sakvinavir4 ↑ 17 puta
* Your doctor may decide that you can take rifabutin and/or voriconazole with a booster (lower dose) of Norvir but a full dose of Norvir must not be taken together with these two medicines. 
* Vaš liječnik možda odluči da uzimate rifabutin i/ili vorikonazol s lijekom Norvir kao pojačivačem
Norvir is used by children 2 years of age or older, adolescents and adults who are infected with HIV, the virus which causes AIDS. 
Norvir je namijenjen za liječenje djece u dobi od 2 godine ili starije, adolescenata i odraslih koji su zaraženi HIV-om, virusom koji uzrokuje sindrom stečene imunodeficijencije (AIDS; engl. acquired immunodeficiency syndrome).
In a study completed in 2003, 50 HIV-1 infected, protease inhibitor and lamivudine naïve children age 4 weeks to 2 years received ritonavir 350 or 450 mg/m2 every 12 hours co-administered with zidovudine 160 mg/m2 every 8 hours and lamivudine 4 mg/kg every 12 hours. 
U ispitivanju dovršenom 2003. godine, 50 djece u dobi od 4 tjedna do 2 godine, zaražene virusom HIV-1, koja prethodno nisu primala ni inhibitor proteaza ni lamivudin, dobivala su ritonavir 350 ili 450 mg/m2 svakih 12 sati istodobno sa zidovudinom 160 mg/m2 svakih 8 sati i lamivudinom 4 mg/kg svakih 12 sati.
Common Increased urination, renal impairment (e.g. oliguria, elevated creatinine) 
Često Povećano mokrenje, oštećenje bubrega (npr. oligurija, povišen kreatinin)
For more detailed dose recommendations, including those for children, see the Package Leaflet of the anti-HIV medicines Norvir is given in combination with. 
Više potankosti o preporučenim dozama, uključujući doziranje u djece, naći ćete u uputi o lijeku za lijek u kombinaciji s kojim se Norvir daje.
Common Hepatitis (including increased AST, ALT, GGT), blood bilirubin increased (including jaundice) 
Često Hepatitis (uključujući povišenje AST-a, ALT-a i GGT-a), povišenje bilirubina u krvi
Anti-infectives 
Antiinfektivi
Raltegravir Co-adminsitration of ritonavir and raltegravir results in a minor reduction in raltegravir levels 
Raltegravir Istodobna primjena ritonavira i raltegravira dovodi do blagog sniženja razina raltegravira.
− antifungals (e.g. ketoconazole, itraconazole); 
− protugljivične lijekove (npr. ketokonazol, itrakonazol);
Beige/pale yellow to yellow powder. 
Prašak za oralnu suspenziju Bež/svijetlo žuti do žuti prašak