natgillin/translations-raw huggingface dataset:
Therefore, inhibitors of these isoenzymes may reduce sildenafil clearance and inducers of these isoenzymes may increase sildenafil clearance. 
Zbog toga inhibitori tih izoenzima mogu smanjiti klirens sildenafila, a induktori ovih izoenzima mogu povećati klirens sildenafila.
Healthy, elderly volunteers (65 years or over) had a reduced clearance of sildenafil, resulting in approximately 90% higher plasma concentrations of sildenafil and the active N-desmethyl metabolite compared to those seen in healthy younger volunteers (18-45 years). 
Zdravi stariji dobrovoljci (65 godina ili stariji) imali su smanjeni klirens sildenafila, što je rezultiralo približno 90% višim koncentracijama sildenafila i aktivnog N-dezmetil metabolita u plazmi u usporedbi s koncentracijama opaženim u zdravih mlađih dobrovoljaca (18-45 godina).
Symptoms may include severe peeling and swelling of the skin, blistering of the mouth, genitals and around the eyes, fever. 
Simptomi mogu uključivati jako ljuštenje i oticanje kože, plikove u ustima, na genitalijama i oko očiju, vrućicu.
Population pharmacokinetic analysis of clinical trial data indicated a reduction in sildenafil clearance when co-administered with CYP3A4 inhibitors (such as ketoconazole, erythromycin, cimetidine). 
Populacijska farmakokinetička analiza podataka iz kliničkog ispitivanja pokazuje smanjenje klirensa sildenafila kada se primjenjuje istodobno s CYP3A4 inhibitorima (kao što su ketokonazol, eritromicin, cimetidin).
Sildenafil (50 mg) did not potentiate the increase in bleeding time caused by acetyl salicylic acid (150 mg). 
Sildenafil (50 mg) nije potencirao produljenje vremena krvarenja, izazvano acetilsalicilnom kiselinom (150 mg).
These decreases in blood pressure are consistent with the vasodilatory effects of sildenafil, probably due to increased cGMP levels in vascular smooth muscle. 
Ova sniženja krvnog tlaka su u skladu s vazodilatatornim učincima sildenafila, vjerojatno zbog povišenih vrijednosti cGMP u glatkim mišićima krvnih žila.
In addition, N-desmethyl metabolite AUC and Cmax values were significantly increased by 200% and 79% respectively. 
Nadalje, vrijednosti AUC i Cmax N-dezmetil metabolita bile su značajno povećane, 200% odnosno 79%.
Chest pain, Fatigue, Feeling hot 
Bol u prsima, umor, osjećaj vrućine
This metabolite has a phosphodiesterase selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50% that of the parent drug. 
Ovaj metabolit ima profil selektivnosti za fosfodiesterazu koji je sličan sildenafilu te in vitro djelovanje na PDE5 koje iznosi približno 50% od onog za ishodišni lijek.
There is a 10-fold selectivity over PDE6 which is involved in the phototransduction pathway in the retina. 
Prisutna je 10 puta veća selektivnost u usporedbi s PDE6 koja je uključena u fototransdukcijski put u mrežnici.
Based on efficacy and tolerability, the dose may be increased to 100 mg or decreased to 25 mg. 
S obzirom na djelotvornost i podnošljivost, doza se može povisiti do 100 mg ili sniziti do 25 mg.
This medicine is used to treat pulmonary arterial hypertension (i.e. high blood pressure in the lungs) and chronic thromboembolic pulmonary hypertension (i.e. high blood pressure in the lungs secondary to blood clots). 
Ovaj lijek se primjenjuje u liječenju plućne arterijske hipertenzije (kod visokog krvnog tlaka u plućima) i kronične tromboembolijske plućne hipertenzije (kod visokog krvnog tlaka u plućima kao posljedica stvaranja krvnih ugrušaka).
This medicine allows an erection to last long enough for you to satisfactorily complete sexual activity. 
Ovaj lijek osigurava dovoljno dugo trajanje erekcije za zadovoljavajući spolni odnos.
Nausea, Dyspepsia 
Mučnina, dispepsija
The side effects reported in association with the use of sildenafil are usually mild to moderate and of a short duration. 
Nuspojave zabilježene kod primjene sildenafila obično su blage do umjerene i kratko traju.
Sildenafil ratiopharm will only work when you are sexually stimulated. 
Sildenafil ratiopharm djeluje samo uz seksualnu stimulaciju.
Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness. 
Unutar svake skupine učestalosti, nuspojave su prikazane prema ozbiljnosti, silaznim redoslijedom.
These additional blood pressure reductions were of a similar magnitude to those seen when sildenafil was administered alone to healthy volunteers (see section 5.1). 
Ova dodatna sniženja krvnog tlaka bila su po jačini slična onima koja su uočena kod zasebne primjene sildenafila zdravim dobrovoljcima (vidjeti dio 5.1).
The safety of sildenafil has not been studied in the following sub-groups of patients and its use is therefore contraindicated: severe hepatic impairment, hypotension (blood pressure < 90/50 mmHg), recent history of stroke or myocardial infarction and known hereditary degenerative retinal disorders such as retinitis pigmentosa (a minority of these patients have genetic disorders of retinal phosphodiesterases). 
Sigurnost sildenafila nije ispitana u sljedećim podskupinama bolesnika te je njegova primjena stoga kontraindicirana: teško oštećenje jetre, hipotenzija (krvni tlak <90/50 mm Hg), anamneza nedavnog moždanog udara ili infarkta miokarda i poznati nasljedni degenerativni poremećaji retine kao što su retinitis pigmentosa (manji dio tih bolesnika ima genetske poremećaje retinalnih fosfodiesteraza).
Hypertension, Hypotension 
Hipertenzija, hipotenzija
Sildenafil (100 mg) did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates. 
Sildenafil (100 mg) nije utjecao na farmakokinetiku stanja dinamičke ravnoteže inhibitora HIV proteaze, sakvinavira i ritonavira, koji su CYP3A4 supstrati.
Take ½ or 1 film-coated tablet of Sildenafil ratiopharm as prescribed by your doctor about 1 hour before sexual activity. 
Uzmite ½ ili 1 filmom obloženu tabletu lijeka Sildenafil ratiopharm, prema uputama Vašeg liječnika, oko sat vremena prije spolnog odnosa.
No significant interactions were shown when sildenafil (50 mg) was co-administered with tolbutamide (250 mg) or warfarin (40 mg), both of which are metabolised by CYP2C9. 
Nisu zabilježene značajne interakcije kod istodobne primjene sildenafila (50 mg) s tolbutamidom (250 mg) ili varfarinom (40 mg), lijekovima koji se metaboliziraju putem CYP2C9.
There was no effect on sperm motility or morphology after single 100 mg oral doses of sildenafil in healthy volunteers (see section 5.1). 
Nije bilo učinka na motilitet ili morfologiju spermija nakon jednokratnih peroralnih doza od 100 mg sildenafila kod zdravih dobrovoljaca (vidjeti dio 5.1).
What Sildenafil ratiopharm contains - The active substance is sildenafil. 
Što Sildenafil ratiopharm sadrži - Djelatna tvar je sildenafil.
In three specific drug-drug interaction studies, the alpha-blocker doxazosin (4 mg and 8 mg) and sildenafil (25 mg, 50 mg, or 100 mg) were administered simultaneously to patients with benign prostatic hyperplasia (BPH) stabilized on doxazosin therapy. 
U tri specifična ispitivanja interakcije lijek-lijek, alfa-blokator doksazosin (4 mg i 8 mg) i sildenafil (25 mg, 50 mg ili 100 mg) primijenjeni su istodobno u bolesnika s benignom hiperplazijom prostate (BHP) stabiliziranima na terapiji doksazosinom.
In a specific interaction study, where sildenafil (100 mg) was co-administered with amlodipine in hypertensive patients, there was an additional reduction on supine systolic blood pressure of 8 mmHg. 
U specifičnom ispitivanju interakcije, gdje se sildenafil (100 mg) primjenjivao istodobno s amlodipinom u bolesnika s hipertenzijom, došlo je do dodatnog sniženja sistoličkog krvnog tlaka u ležećem položaju od 8 mmHg.
The mean maximum decreases in supine systolic blood pressure following 100 mg oral dosing of sildenafil was 8.4 mmHg. 
Srednje maksimalno sniženje sistoličkog krvnog tlaka u ležećem položaju nakon oralnog doziranja sildenafila od 100 mg iznosilo je 8,4 mmHg.
In a small size placebo-controlled study of patients with documented early age-related macular degeneration (n = 9), sildenafil (single dose, 100 mg) demonstrated no significant changes in the visual tests conducted (visual acuity, Amsler grid, colour discrimination simulated traffic light, Humphrey perimeter and photostress). 
U malom placebom kontroliranom ispitivanju bolesnika s dokumentiranom ranom makularnom degeneracijom povezanom s dobi (n=9), sildenafil (jednokratna doza, 100 mg) nije prikazao značajne promjene u provedenim testovima vida (oštrina vida, Amslerova mreža, raspoznavanje boja simulacijom semafora, Humphreyev perimetar i fotostres).
In these study populations, mean additional reductions of supine blood pressure of 7/7 mmHg, 9/5 mmHg, and 8/4 mmHg, and mean additional reductions of standing blood pressure of 6/6 mmHg, 11/4 mmHg, and 4/5 mmHg, respectively, were observed. 
U ispitivanoj populaciji uočena su dodatna sniženja krvnog tlaka u ležećem položaju srednjih vrijednosti od 7/7 mmHg, 9/5 mmHg odnosno 8/4 mmHg te dodatna sniženja krvnog tlaka u stojećem položaju srednjih vrijednosti od 6/6 mmHg, 11/4 mmHg odnosno 4/5 mmHg.
Although specific interaction studies were not conducted for all medicinal products, population pharmacokinetic analysis showed no effect of concomitant treatment on sildenafil pharmacokinetics when grouped as CYP2C9 inhibitors (such as tolbutamide, warfarin, phenytoin), CYP2D6 inhibitors (such as selective serotonin reuptake inhibitors, tricyclic antidepressants), thiazide and related diuretics, loop and potassium sparing diuretics, angiotensin converting enzyme inhibitors, calcium channel blockers, beta-adrenoreceptor antagonists or inducers of CYP450 metabolism (such as rifampicin, barbiturates). 
Iako specifična ispitivanja interakcija nisu provedena za sve lijekove, populacijska farmakokinetička analiza nije ukazala na djelovanje istodobno primijenjenih terapija na farmakokinetiku sildenafila, grupiranih kao CYP2C9 inhibitori (kao što su tolbutamid, varfarin, fenitoin), CYP2D6 inhibitori (kao što su selektivni inhibitori ponovne pohrane serotonina, triciklični antidepresivi), tiazid i srodni diuretici, diuretici Henleove petlje i oni koji štede kalij, inhibitori angiotenzin konvertirajućeg enzima, blokatori kalcijevih kanala, antagonisti beta-adrenoreceptora ili induktori CYP450 metabolizma (kao što su rifampicin, barbiturati).
Take 1 film-coated tablet of Sildenafil ratiopharm about 1 hour before sexual activity. 
Uzmite 1 filmom obloženu tabletu lijeka Sildenafil ratiopharm oko sat vremena prije spolnog odnosa.
- if you have ever suffered from loss of vision due to an eye condition known as “stroke of the eye” (non-arteritic anterior ischaemic optic neuropathy, NAION). 
ako ste ikada imali gubitak vida zbog stanja koje se zove "infarkt oka" (nearteritična prednja ishemijska optička neuropatija, NAION).
In clinical studies, riociguat has been shown to augment the hypotensive effects of PDE5 inhibitors. 
U kliničkim ispitivanjima, riociguat je pokazao da pojačava hipotenzivni učinak inhibitora PDE5.
Sildenafil showed no effect on cardiac output, and did not impair blood flow through the stenosed coronary arteries. 
Sildenafil nije pokazao učinak na minutni volumen srca te nije narušio protok krvi kroz sužene koronarne arterije.
In addition, initiation of sildenafil at a dose of 25 mg should be considered (see sections 4.4 and 4.5). 
Nadalje, potrebno je razmotriti primjenu početne doze sildenafila od 25 mg (vidjeti dijelove 4.4 i 4.5).
The pharmacokinetics of sildenafil in patients with severely impaired hepatic function have not been studied. 
Farmakokinetika sildenafila u bolesnika s teškim oštećenjem funkcije jetre nije ispitivana.
Agents for the treatment of erectile dysfunction, including sildenafil, should be used with caution in patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis or Peyronie's disease), or in patients who have conditions which may predispose them to priapism (such as sickle cell anaemia, multiple myeloma or leukaemia). 
Sredstva za liječenje erektilne disfunkcije, uključujući sildenafil, treba oprezno primjenjivati u bolesnika s anatomskom deformacijom penisa (kao što su angulacija, kavernozna fibroza ili Peyronijeva bolest) ili u bolesnika koji imaju stanja koja ih mogu predisponirati za prijapizam (kao što su anemija srpastih stanica, multipli mijelom ili leukemija).
Cimetidine (800 mg), a cytochrome P450 inhibitor and non-specific CYP3A4 inhibitor, caused a 56% increase in plasma sildenafil concentrations when co-administered with sildenafil (50 mg) to healthy volunteers. 
(800 mg), inhibitor citokroma P450 i nespecifični CYP3A4 inhibitor, uzrokovao je 56%-tni porast koncentracija sildenafila u plazmi kada se primjenjivao istodobno sa sildenafilom (50 mg) u zdravih dobrovoljaca.
Symptoms include sudden wheeziness, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat. 
Simptomi ulkjučuju iznenadno piskanje, otežano disanje ili omaglicu, oticanje vjeđa, lica, usnica ili grla.
If you feel dizzy, or if your vision or hearing is affected after taking Sildenafil ratiopharm, do not drive or operate any tools or machines. 
Ako osjetite omaglicu ili ako imate problema s vidom ili sluhom nakon uzimanja lijeka Sildenafil ratiopharm, ne smijete upravljati vozilima, odnosno rukovati alatima ili strojevima.
Grapefruit juice is a weak inhibitor of CYP3A4 gut wall metabolism and may give rise to modest increases in plasma levels of sildenafil. 
Sok od grejpa slab je inhibitor CYP3A4 uključenog u metabolizam u stijenci crijeva i može izazvati umjereni porast razina sildenafila u plazmi.
In a study of the haemodynamic effects of a single oral 100 mg dose of sildenafil in 14 patients with severe coronary artery disease (CAD) (> 70% stenosis of at least one coronary artery), the mean resting systolic and diastolic blood pressures decreased by 7% and 6% respectively compared to baseline. 
U ispitivanju hemodinamičkih učinaka jednokratne oralne doze sildenafila od 100 mg u 14 bolesnika s teškom bolesti koronarnih arterija (> 70% stenoza barem jedne koronarne arterije), srednji sistolički i dijastolički krvni tlak u mirovanju je snižen za 7%, odnosno 6% u usporedbi s početnom vrijednosti.
Sildenafil ratiopharm is a treatment for adult men with erectile dysfunction, sometimes known as impotence. 
Sildenafil ratiopharm je namijenjen liječenju odraslih muškaraca s erektilnom disfunkcijom, ponekad zvanom pod nazivom impotencija.
Vertigo, Tinnitus 
Vrtoglavica, tinitus
Although no increased incidence of adverse events was observed in these patients, when sildenafil is administered concomitantly with CYP3A4 inhibitors, a starting dose of 25 mg should be considered. 
Iako u tih bolesnika nije opažena povećana incidencija štetnih događaja, kod istodobne primjene sildenafila s CYP3A4 inhibitorima potrebno je razmotriti primjenu početne doze od 25 mg.
Nasal congestion 
Nazalna kongestija
In volunteers with mild to moderate renal impairment (creatinine clearance = 30-80 mL/min), the pharmacokinetics of sildenafil were not altered after receiving a 50 mg single oral dose. 
U dobrovoljaca s blagim do umjerenim poremećajem bubrega (klirens kreatinina = 30-80 ml/min), nakon uzimanja jednokratne oralne doze od 50 mg nije bilo promjena u farmakokinetici sildenafila.
Patients with increased susceptibility to vasodilators include those with left ventricular outflow obstruction (e.g. aortic stenosis, hypertrophic obstructive cardiomyopathy), or those with the rare syndrome of multiple system atrophy manifesting as severely impaired autonomic control of blood pressure. 
Bolesnici s povećanom osjetljivošću na vazodilatatore obuhvaćaju one s opstrukcijom izlaznog trakta lijevog ventrikula (npr. aortna stenoza, hipertrofična opstruktivna kardiomiopatija) ili bolesnike s rijetkim sindromom multiple sustavne atrofije koja se manifestira teškim poremećajem autonomne kontrole krvnog tlaka.
Merckle GmbH Ludwig-Merckle-Strasse 3 89143 Blaubeuren Germany 
Merckle GmbH Ludwig-Merckle-Strasse 3 89143 Blaubeuren Njemačka
With the exception of ritonavir for which co-administration with sildenafil is not advised (see section 4.4), a starting dose of 25 mg should be considered in patients receiving concomitant treatment with CYP3A4 inhibitors (see section 4.5). 
S iznimkom ritonavira, kod kojeg se istodobna primjena sa sildenafilom ne savjetuje (vidjeti dio 4.4), u bolesnika koji se istodobno liječe CYP3A4 inhibitorima potrebno je razmotriti primjenu početne doze od 25 mg (vidjeti dio 4.5).
Serious cardiovascular events, including myocardial infarction, unstable angina, sudden cardiac death, ventricular arrhythmia, cerebrovascular haemorrhage, transient ischaemic attack, hypertension and hypotension have been reported post-marketing in temporal association with the use of sildenafil. 
Ozbiljni kardiovaskularni događaji, uključujući infarkt miokarda, nestabilnu anginu, iznenadnu srčanu smrt, ventrikularnu aritmiju, cerebrovaskularno krvarenje, tranzitornu ishemijsku ataku, hipertenziju i hipotenziju bili su prijavljeni u razdoblju nakon stavljanja lijeka u promet, kao vremenski povezani s primjenom sildenafila.
Initiation of sildenafil at a dose of 25 mg should be considered (see section 4.2). 
Potrebno je razmotriti početak liječenja sildenafilom u dozi od 25 mg (vidjeti dio 4.2).
If you experience sudden decrease or loss of vision, stop taking Sildenafil ratiopharm and contact your doctor IMMEDIATELY. 
Ako primijetite nagli gubitak vida, prestanite uzimati Sildenafil ratiopharm i ODMAH se obratite svom liječniku.
*Reported during post-marketing surveillance only **Visual colour distortions: Chloropsia, Chromatopsia, Cyanopsia, Erythropsia and Xanthopsia ***Lacrimation disorders: Dry eye, Lacrimal disorder and Lacrimation increased 
*Prijavljeno isključivo nakon stavljanja lijeka u promet **Vizualni poremećaj percepcije boja: kloropsija, kromatopsija,cijanopsija, eritropsija i ksantopsija ***Poremećaji suzenja: suho oko, suzni poremećaji i pojačano suzenje
The corresponding change in supine diastolic blood pressure was 5.5 mmHg. 
Odgovarajuća promjena dijastoličkog krvnog tlaka u ležećem položaju iznosila je 5,5 mmHg.
If this occurs during or after intercourse: Get in a semi-sitting position and try to relax. 
• Zauzmite polusjedeći položaj i pokušajte se opustiti.
- if you suffer from kidney or liver problems. 
- ako imate problema s bubrezima ili jetrom.
Pooling of the following classes of antihypertensive medication, diuretics, beta-blockers, ACE inhibitors, angiotensin II antagonists, antihypertensive medicinal products (vasodilator and centrally-acting), adrenergic neurone blockers, calcium channel blockers and alpha-adrenoceptor blockers, showed no difference in the side effect profile in patients taking sildenafil compared to placebo treatment. 
Analiza podataka sljedećih klasa antihipertenzivnih lijekova: diuretika, beta-blokatora, ACE inhibitora, antagonista angiotenzina II, antihipertenzivnih lijekova (vazodilatatora i onih sa središnjim djelovanjem), blokatora adrenergičkog neurona, blokatora kalcijevih kanala i blokatora alfaadrenoceptora, nije pokazala razlike u profilu nuspojava u bolesnika koji uzimaju sildenafil u usporedbi s liječenjem placebom.
Cases of non-arteritic anterior ischaemic optic neuropathy, a rare condition, have been reported spontaneously and in an observational study in connection with the intake of sildenafil and other PDE5 inhibitors (see section 4.8). 
Slučajevi nearteritične anteriorne ishemijske optičke neuropatije, rijetkog stanja, prijavljeni su spontano i u opservacijskom ispitivanju vezano uz uzimanje sildenafila i drugih PDE5 inhibitora (vidjeti dio 4.8).
What Sildenafil ratiopharm is and what it is used for What you need to know before you take Sildenafil ratiopharm How to take Sildenafil ratiopharm Possible side effects 
Što je Sildenafil ratiopharm i za što se koristi Što morate znati prije nego počnete uzimati Sildenafil ratiopharm
If you are not certain, ask your doctor or pharmacist. 
Ako niste sigurni, provjerite sa svojim liječnikom ili ljekarnikom.
In order to reduce the probability of these symptoms occurring, you should start taking Sildenafil ratiopharm only when you are already well controlled on a regular daily dose of your alpha blocker. 
Kako biste smanjili vjerojatnost pojave tih simptoma, Sildenafil ratiopharm smijete početi uzimati tek nakon što ste redovnom dnevnom primjenom alfablokatora postigli dobru kontrolu krvnog tlaka.
Based on efficacy and tolerability, the dose may be increased step-wise to 50 mg up to 100 mg as necessary. 
Na temelju djelotvornosti i podnošljivosti, doza se može postupno povisiti na 50 mg sve do 100 mg prema potrebi.
A medical history and physical examination should be undertaken to diagnose erectile dysfunction and determine potential underlying causes, before pharmacological treatment is considered. 
Prije odluke o farmakološkom liječenju, potrebno je uzeti medicinsku anamnezu i izvršiti fizikalni pregled radi dijagnoze erektilne disfunkcije i određivanja mogućih primarnih uzroka.
Concomitant administration of sildenafil to patients taking alpha-blocker therapy may lead to symptomatic hypotension in a few susceptible individuals. 
Istodobna primjena sildenafila u bolesnika koji primaju terapiju alfa-blokatorom može dovesti do simptomatske hipotenzije u manjeg broja osjetljivih osoba.
Tachycardia, Palpitations 
Tahikardija, palpitacije
(≥ 1/100 and 
(≥1/100 i
Other medicines and Sildenafil ratiopharm 
Drugi lijekovi i Sildenafil ratiopharm
Cases of visual defects have been reported spontaneously in connection with the intake of sildenafil and other PDE5 inhibitors (see section 4.8). 
Slučajevi poremećaja vida prijavljeni su spontano vezano uz uzimanje sildenafila i drugih PDE5 inhibitora (vidjeti dio 4.8).
In volunteers with mild to moderate hepatic cirrhosis (Child-Pugh A and B) sildenafil clearance was reduced, resulting in increases in AUC (84%) and Cmax (47%) compared to age-matched volunteers with no hepatic impairment. 
U dobrovoljaca s blagom do umjerenom cirozom jetre (Child-Pugh A i B) klirens sildenafila bio je snižen, što je rezultiralo porastom AUC (84%) i Cmax (47%) u usporedbi s dobrovoljcima odgovarajućim po dobi bez oštećenja jetre.
Across all trials, the proportion of patients reporting improvement on sildenafil were as follows: psychogenic erectile dysfunction (84%), mixed erectile dysfunction (77%), organic erectile dysfunction (68%), elderly (67%), diabetes mellitus (59%), ischaemic heart disease (69%), hypertension (68%), TURP (61%), 
Uzimajući u obzir sva ispitivanja, udio bolesnika koji su prijavili poboljšanje uz sildenafil bio je sljedeći: psihogena erektilna disfunkcija (84%), mješovita erektilna disfunkcija (77%), organska erektilna disfunkcija (68%), starije osobe (67%), dijabetes melitus (59%), ishemična bolest srca (69%), hipertenzija (68%), TURP (61%), radikalna prostatektomija (43%), ozljeda leđne moždine (83%), depresija (75%).
If you take more Sildenafil ratiopharm than you should Men who take too much Sildenafil ratiopharm may experience more side effects or may get severe muscle pain. 
Ako uzmete više lijeka Sildenafil ratiopharm nego što ste trebali Veći broj nuspojava ili jaka bol u mišićima mogu se javiti u muškaraca koji uzmu previše tableta Sildenafil ratiopharm.
Do NOT take Sildenafil ratiopharm if you are taking medicines that contain nitrates (e.g. glycerol trinitrate) or nitric oxide donors (e.g. amyl nitrite, also called “poppers”). 
NE uzimajte Sildenafil ratiopharm ako uzimate lijekove koji sadrže nitrate (primjerice glicerol trinitrat) ili donore dušikovih oksida (primjerice amil nitrit).
In order to get the maximum benefit from your medicine, it is recommended that you avoid alcohol before intake of this medicine. 
Kako biste maksimalno iskoristili prednosti lijeka Sildenafil ratiopharm, preporučuje se izbjegavati alkohol prije primjene ovog lijeka.
Effects of other medicinal products on sildenafil In vitro studies 
Učinci drugih lijekova na sildenafil