Common side effects (may affect up to 1 in 10 people): - blue colour of tissues such as the skin or gums caused by too little oxygen - perceptible increase in frequency or force of heartbeat - swelling in arms or legs or other swelling - chest discomfort - upset stomach, decreased appetite or weight loss - injection site or catheter site redness, swelling, infection or other local reaction - rash or redness, inflammation of the skin, itching, dry skin, pale or transient red appearance - inflammation of skin, tendons, muscles or similar tissues that support body structure - inflammation of a vein - upper abdominal or chest wall pain; abdominal bloating or pain; indigestion or pain in your liver - other pain, including neck, shoulder, groin, bone or throat pain; pain after an operation - muscle spasms or stiffness - feeling cold - tired feeling, drowsiness or sleepiness - burning, pricking/tingling sensation, diminished sensitivity to sensation or feeling a sensation without stimulus - involuntary shaking movement - dehydration - low concentration of potassium in blood - mucosal inflammation - nose, throat, or sinus congestion or inflammation - infections of the upper respiratory tract (such as a cold) or the urinary tract (such as a bladder infection) - generalised infection - Herpes simplex (virus) infection - productive cough, wheezing or exertional or exacerbated shortness of breath - spitting of blood or nosebleed - fluid in the lung cavity - blood in urine, difficulty or pain in urination or frequent urination - difficulty sleeping, depression, anxiety or confusion - dizziness - ears ringing - blurred vision - hair loss - difficult, painful menstruation - hearing loss - low number of white blood cells with or without fever, low number of platelets 
- crvenilo na mjestu injekcije ili katetera, oteklina ili druge reakcije na mjestu primjene - osip ili crvenilo, upala kože, svrbež, suha koža, bljedilo ili prolazno crvenilo - upala kože, tetiva, mišića ili sličnih tkiva koja podupiru strukturu tijela - upala vena - bol u gornjem dijelu trbuha ili u stijenci prsnog koša; nadutost trbuha ili bol; probavne tegobe ili bol u jetri - druga bol, uključujući bol u vratu, ramenima, preponama, kostima ili grlu; bol nakon operacije - grčevi ili ukočenost mišića - osjećaj hladnoće - osjećaj umora, omamljenosti ili pospanosti - pečenje, osjećaj bockanja ili trnaca, smanjena osjetljivost na podražaj ili osjećaj nadraženosti bez podražaja - nevoljni drhtavi pokreti - dehidracija - niska koncentracija kalija u krvi - upala sluznice - upala ili začepljenost nosa, grla ili sinusa - upala gornjeg dišnog sustava (poput prehlade) ili mokraćnog sustava (poput upale mjehura) - opća infekcija - infekcija s virusom Herpes simplex - kašalj s iskašljavanjem, piskanje ili gubitak daha u naporu ili pogoršanje nedostatka daha - iskašljavanje krvi ili krvarenje iz nosa - tekućina u ležištu pluća - krv u mokraći, teško ili bolno mokrenje ili često mokrenje - teškoće sa spavanjem, depresija, tjeskoba ili smetenost - omaglica - zvonjava u ušima - zamućen vid - ispadanje kose - bolna mjesečnica - gubitak sluha - snižen broj bijelih krvnih stanica sa ili bez vrućice, snižen broj trombocita