natgillin/translations-raw huggingface dataset:
Therefore there is the potential of drug interactions mediated by inhibition of transporters. 
Stoga su moguće interakcije između lijekova uslijed inhibicije prijenosnika.
The effect of tadalafil is more potent on PDE5 than on other phosphodiesterases. 
Djelovanje tadalafila na PDE5 snažnije je nego na druge fosfodiesteraze.
This drug is used to treat pulmonary arterial hypertension (i.e., high blood pressure in the lungs) and chronic thromboembolic pulmonary hypertension (i.e., high blood pressure in the lungs secondary to blood clots). 
Taj se lijek koristi za liječenje plućne arterijske hipertenzije (tj. povišenog krvnog tlaka u plućima) i kronične tromboembolijske plućne hipertenzije (tj. povišenog krvnog tlaka u plućima koji je posljedica krvnih ugrušaka).
In study subjects whose blood pressure was not controlled, the reduction was greater although this reduction was not associated with hypotensive symptoms in the majority of subjects. 
U ispitanika u kojih krvni tlak nije bio kontroliran smanjenje je bilo veće, ali u većine ispitanika nije bilo povezano s hipotenzivnim simptomima.
If you are taking riociguat or are unsure tell your doctor. 
Ako uzimate riocigvat ili niste sigurni, obavijestite svog liječnika.
This is thought to result from the combined effects of nitrates and tadalafil on the nitric oxide/cGMP pathway. 
Smatra se da je to posljedica kombiniranog djelovanja nitrata i tadalafila na signalni put dušikova oksida/cGMP-a.
Drinking alcohol may affect your ability to get an erection and may temporarily lower your blood pressure. 
Konzumiranje alkohola može utjecati na sposobnost postizanja erekcije i privremeno sniziti krvni tlak.
CIALIS has negligible influence on the ability to drive or use machines. 
CIALIS zanemarivo utječe na sposobnost upravljanja vozilima i rada sa strojevima.
This results in smooth muscle relaxation and inflow of blood into the penile tissues, thereby producing an erection. 
To dovodi do opuštanja glatkih mišića i dotoka krvi u tkivo penisa, čime se postiže erekcija.
In subjects taking multiple antihypertensives, the ambulatory-blood-pressure changes appeared to relate to the degree of blood-pressure control. 
U bolesnika koji su uzimali nekoliko antihipertenziva činilo se da su izmjerene promjene krvnog tlaka povezane sa stupnjem kontrole krvnog tlaka.
Dose adjustments are not required in elderly patients. 
Nije potrebno prilagođavati dozu u starijih bolesnika.
Since benign prostatic hyperplasia and prostate cancer may have the same symptoms, your doctor will check you for prostate cancer before starting treatment with CIALIS for benign prostatic hyperplasia. 
Budući da benigna hiperplazija i rak prostate mogu imati iste simptome, liječnik će napraviti pretrage za rak prostate prije početka primjene lijeka CIALIS za benignu hiperplaziju prostate.
The only pharmacodynamic effect was a small (3.5 bpm) increase in heart rate. 
Jedini farmakodinamički učinak bilo je malo ubrzanje srčanog ritma (3,5 otkucaja u minuti).
Frequency convention: very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1000 to 
Kategorije učestalosti: vrlo često (≥ 1/10), često (≥ 1/100 i < 1/10), manje često (≥ 1/1000 i < 1/100),
The adverse reactions reported were transient, and generally mild or moderate. 
Prijavljene nuspojave bile su prolazne te u pravilu blagog ili umjerenog intenziteta.
In haemodialysis patients, Cmax was 41 % higher than that observed in healthy subjects. 
U bolesnika na hemodijalizi je Cmax bio 41% veći nego u zdravih ispitanika.
Prior to initiating any treatment for erectile dysfunction, physicians should consider the cardiovascular status of their patients, since there is a degree of cardiac risk associated with sexual activity. 
Prije uvođenja bilo kakvog liječenja erektilne disfunkcije liječnici trebaju razmotriti kardiovaskularni status svojih bolesnika jer se uz seksualnu aktivnost veže određen stupanj srčanog rizika.
The recommended starting dose is one 10 mg tablet before sexual activity. 
Preporučena početna doza je jedna tableta od 10 mg koja se uzima prije seksualne aktivnosti.
This finding is consistent with the low affinity of tadalafil for PDE6 compared to PDE5. 
Ovaj je nalaz u skladu s niskim afinitetom tadalafila za PDE6 u odnosu na PDE5.
Cases of sudden hearing loss have been reported after the use of tadalafil. 
Prijavljeni su slučajevi iznenadnog gubitka sluha nakon primjene tadalafila.
When dogs were treated there was reduced sperm development in the testes. 
Kod primjene ovog lijeka u pasa primijećeno je smanjeno stvaranje sperme u testisima.
Healthy elderly subjects (65 years or over), had a lower oral clearance of tadalafil, resulting in 25 % higher exposure (AUC) relative to healthy subjects aged 19 to 45 years. 
Zdravi stariji ispitanici (65 godina i stariji) imali su manji klirens tadalafila nakon peroralne primjene, što je dovelo do 25% veće izloženosti (AUC) u odnosu na zdrave ispitanike u dobi od 19 do 45 godina.
Some medicines may be affected by CIALIS or they may affect how well CIALIS will work. 
CIALIS može utjecati na neke lijekove ili oni mogu utjecati na djelovanje lijeka CIALIS.
Detailed information on this medicinal product is available on the website of the European Medicines Agency http://www.ema.europa.eu. 
Detaljnije informacije o ovom lijeku dostupne su na internetskoj stranici Europske agencije za lijekove: http://www.ema.europa.eu.
The majority of headaches reported with CIALIS once-aday dosing are experienced within the first 10 to 30 days of starting treatment. 
U većini se slučajeva glavobolja prijavljena kod primjene lijeka CIALIS jedanput na dan javila unutar prvih 10 do 30 dana nakon početka liječenja.
Although it is not known if the event is directly related to tadalafil, if you experience decreased or sudden hearing loss, stop taking CIALIS and contact your doctor immediately. 
Iako nije poznato je li taj događaj izravno povezan s tadalafilom, ako primijetite slabljenje ili iznenadan gubitak sluha, prestanite uzimati CIALIS i odmah se javite svom liječniku.
Physicians should consider the potential cardiac risk of sexual activity in patients with pre-existing cardiovascular disease. 
Liječnici moraju razmotriti potencijalni rizik za srce tijekom seksualne aktivnosti u bolesnika s postojećom kardiovaskularnom bolešću.
CIALIS has been shown to improve these urinary symptoms as early as 1-2 weeks after starting treatment. 
Pokazalo se da CIALIS ublažava te simptome u mokraćnom sustavu već 1-2 tjedna nakon početka liječenja.
Three studies were conducted in men to assess the potential effect on spermatogenesis of CIALIS 10 mg (one 6-month study) and 20 mg (one 6-month and one 9-month study) administered daily. 
Provedena su tri ispitivanja u muškaraca kako bi se procijenio potencijalni utjecaj svakodnevne primjene lijeka CIALIS u dozi od 10 mg (jedno 6-mjesečno ispitivanje) i 20 mg (jedno 6-mjesečno i jedno
The rate and extent of absorption of tadalafil are not influenced by food, thus CIALIS may be taken with or without food. 
Hrana ne utječe na brzinu i opseg apsorpcije tadalafila, tako da se CIALIS može uzimati s hranom ili bez nje.
Due to increased tadalafil exposure (AUC), limited clinical experience and the lack of ability to influence clearance by dialysis, once-a-day dosing of CIALIS is not recommended in patients with severe renal impairment. 
Zbog povećane izloženosti tadalafilu (AUC), ograničenog kliničkog iskustva i nemogućnosti da se na klirens utječe dijalizom, ne preporučuje se primjena lijeka CIALIS jedanput na dan u bolesnika s teškim oštećenjem bubrežne funkcije.
The mean oral clearance for tadalafil is 2.5 l/h and the mean half-life is 17.5 hours in healthy subjects. 
Prosječan klirens tadalafila nakon peroralne primjene iznosi 2,5 l/h, a prosječan poluvijek u zdravih ispitanika iznosi 17,5 sati.
Before treatment with CIALIS 
Prije liječenja lijekom CIALIS
CYP2C9 substrates (e.g. R-warfarin) 
Supstrati CYP2C9 (npr. R-varfarin)
Consequently, it is not expected to be clinically active at observed metabolite concentrations. 
Stoga se ne očekuje se da će u opaženim koncentracijama biti klinički aktivan.
Tadalafil pharmacokinetics in healthy subjects are linear with respect to time and dose. 
Linearnost/nelinearnost Farmakokinetika tadalafila u zdravih je ispitanika linearna s obzirom na vrijeme i dozu.
Interaction studies were conducted with 10 mg and/or 20 mg tadalafil, as indicated below. 
Provedena su ispitivanja interakcija s tadalafilom u dozama od 10 mg i/ili 20 mg, kako je opisano u nastavku.
Pharmacokinetics determined with a population approach in patients with erectile dysfunction are similar to pharmacokinetics in subjects without erectile dysfunction. 
Farmakokinetika utvrđena populacijskim pristupom u bolesnika s erektilnom disfunkcijom bila je slična farmakokinetici u ispitanika bez erektilne disfunkcije.
de la Industria 30, 28108 Alcobendas, Madrid, Spain. 
Proizvođač: Lilly S.A., Avda. de la Industria 30, 28108 Alcobendas, Madrid, Španjolska
Not all packs sizes may be marketed. 
Na tržištu se ne moraju nalaziti sve veličine pakiranja.
If you have a heart problem you should tell your doctor. 
Ako imate tegoba sa srcem, obavijestite o tome svog liječnika.
MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS BLISTERS 
PODACI KOJE MORA NAJMANJE SADRŽAVATI BLISTER ILI STRIP BLISTER
In clinical studies, tadalafil (5, 10 and 20 mg) was shown to augment the hypotensive effects of nitrates. 
U kliničkim se ispitivanjima pokazalo da tadalafil (5, 10 i 20 mg) pojačava hipotenzivne učinke nitrata.
Tadalafil has vasodilator properties, resulting in mild and transient decreases in blood pressure (see section 5.1) and as such potentiates the hypotensive effect of nitrates (see section 4.3). 
Tadalafil ima vazodilatacijska svojstva koja dovode do blagih i prolaznih sniženja krvnog tlaka (vidjeti dio 5.1) i tako pojačavaju hipotenzivni učinak nitrata (vidjeti dio 4.3).
2 film-coated tablets 4 film-coated tablets 8 film-coated tablets 10 film-coated tablets 12 film-coated tablets 
2 filmom obložene tablete 4 filmom obložene tablete 8 filmom obloženih tableta 10 filmom obloženih tableta 12 filmom obloženih tableta
The overall safety results from this study were generally consistent with the known safety profile of tadalafil and with adverse events (AEs) expected in a paediatric DMD population receiving corticosteroids. 
Sveukupni rezultati za sigurnost iz ovog ispitivanja u načelu su bili u skladu s poznatim sigurnosnim profilom tadalafila, uz nuspojave očekivane u pedijatrijskoj populaciji s DMD-om koja prima kortikosteroide.
Absolute bioavailability of tadalafil following oral dosing has not been determined. 
Apsolutna bioraspoloživost tadalafila nakon peroralne primjene nije utvrđena.
Priapism and anatomical deformation of the penis 
Prijapizam i anatomske deformacije penisa
DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorisation: 12 November 2002 
Datum prvog odobrenja: 12. studenog 2002.
In patients receiving concomitant antihypertensive medicinal products, tadalafil 20 mg may induce a blood pressure decrease, which (with the exception of alpha blockers -see above-) is, in general, minor and not likely to be clinically relevant. 
U bolesnika koji se istodobno liječe antihipertenzivima tadalafil u dozi od 20 mg može izazvati sniženje krvnog tlaka koje je (uz izuzetak alfa-blokatora - vidjeti prethodni odlomak) u pravilu malo i nije vjerojatno da će biti klinički značajno.
CIALIS contains the active substance tadalafil which belongs to a group of medicines called phosphodiesterase type 5 inhibitors. 
CIALIS sadrži djelatnu tvar tadalafil koja pripada skupini lijekova koji se nazivaju inhibitorima fosfodiesteraze tipa 5.
The appropriateness of continued use of the daily regimen should be reassessed periodically. 
Primjerenost kontinuirane svakodnevne primjene lijeka treba povremeno iznova procijeniti.
Although the frequency of reports of dizziness in placebo and tadalafil arms in clinical trials was similar, patients should be aware of how they react to CIALIS, before driving or using machines. 
Iako je u kliničkim ispitivanjima učestalost prijavljivanja omaglice bila podjednaka u skupinama koje su primale placebo odnosno tadalafil, bolesnici moraju biti svjesni kako reagiraju na CIALIS prije nego upravljaju vozilom ili rukuju strojevima.
Tadalafil (10 mg except for studies with angiotensin II receptor blockers and amlodipine in which a 20 mg dose was applied) had no clinically significant interaction with any of these classes. 
Tadalafil (10 mg, osim u ispitivanjima s blokatorima receptora angiotenzina II i amlodipinom, gdje je primijenjena doza od 20 mg) ni s jednom od navedenih skupina nije imao klinički značajne interakcije.
CIALIS, should be used with caution in patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis or Peyronie's disease), or in patients who have conditions which may predispose them to priapism (such as sickle cell anaemia, multiple myeloma or leukaemia). 
CIALIS treba primjenjivati uz oprez u bolesnika s anatomskim deformacijama penisa (poput angulacije, kavernozne fibroze ili Peyronijeve bolesti) i u bolesnika koji pate od nekih stanja koja mogu biti predispozicija za prijapizam (poput anemije srpastih stanica, multiplog mijeloma ili leukemije).
However, you have been given the dose of one 20mg tablet as your doctor has decided that the recommended dose of 10mg is too weak. 
propisana Vam je doza od jedne tablete od 20 mg jer je Vaš liječnik odlučio da preporučena doza od
- riociguat. 
- riocigvat.
Effects of other substances on tadalafil 
Učinci drugih lijekova na tadalafil
In patients who anticipate a frequent use of CIALIS (i.e., at least twice weekly) a once daily regimen with the lowest doses of CIALIS might be considered suitable, based on patient choice and the physician's judgement. 
U bolesnika koji očekuju učestalu primjenu lijeka CIALIS (tj. najmanje dvaput tjedno) možda će biti primjerena primjena najniže doze lijeka jedanput na dan, ovisno o želji bolesnika i prosudbi liječnika.
When initiating daily treatment with tadalafil, appropriate clinical considerations should be given to a possible dose adjustment of the antihypertensive therapy. 
Kada se započinje liječenje tadalafilom, treba napraviti odgovarajuću kliničku procjenu moguće prilagodba doze antihipertenziva.
The role of transporters (for example p-glycoprotein) in the disposition of tadalafil is not known. 
Nije poznata uloga prijenosnika (primjerice, p-glikoproteina) u raspoloživosti tadalafila.
One of these studies assessed improvements in erectile dysfunction and signs and symptoms of benign prostatic hyperplasia in patients with both conditions. 
U jednom od tih ispitivanja procijenjeno je poboljšanje erektilne disfunkcije i ublažavanje znakova i simptoma benigne hiperplazije prostate u bolesnika koji su bolovali od obje bolesti.
Warnings and precautions Talk to your doctor before taking CIALIS. 
Obratite se svom liječniku prije nego uzmete CIALIS.
How to take CIALIS 
Kako uzimati CIALIS
Based on the results of a clinical study in which 150 subjects receiving daily doses of tadalafil 20 mg for 7 days and 0.4 mg sublingual nitroglycerin at various times, this interaction lasted for more than 24 hours and was no longer detectable when 48 hours had elapsed after the last tadalafil dose. 
Na temelju rezultata iz kliničkog ispitivanja u kojem je 150 ispitanika primalo dozu od 20 mg tadalafila na dan tijekom 7 dana i dozu od 0,4 mg nitroglicerina primijenjena sublingvalno u različito doba, ta je interakcija trajala dulje od 24 sata, a nije više bila mjerljiva 48 sati nakon primjene posljednje doze tadalafila.
Preclinical studies showed an additive systemic blood pressure lowering effect when PDE5 inhibitors were combined with riociguat. 
Pretklinička ispitivanja pokazala su aditivan učinak na sniženje sistemskog krvnog tlaka kada su se inhibitori PDE5 primjenjivali u kombinaciji s riocigvatom.
When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels of cGMP in the corpus cavernosum. 
Kad seksualna stimulacija izazove lokalno otpuštanje dušikova oksida, tadalafil inhibira PDE5 i tako dovodi do povišenih koncentracija cGMP-a u šupljikavom tijelu.
The resulting vascular relaxation increases blood perfusion which may be the mechanism by which symptoms of benign prostatic hyperplasia are reduced. 
Posljedično opuštanje krvni žila povećava perfuziju krvi, što bi mogao biti mehanizam kojim se ublažavaju simptomi benigne hiperplazije prostate.
Effects of tadalafil on other medicinal products 
Učinci tadalafila na druge lijekove
CIALIS 5 mg is used to treat adult men with: - erectile dysfunction. 
CIALIS 5 mg tablete primjenjuju se za liječenje odraslih muškaraca koji imaju: - erektilnu disfunkciju.
In those patients in whom tadalafil 10 mg does not produce an adequate effect, 20 mg might be tried. 
U bolesnika u kojih tadalafil u dozi od 10 mg ne izazove odgovarajući učinak može se pokušati s dozom od 20 mg.
Tadalafil is also > 10,000-fold more potent for PDE5 than for PDE7 through PDE10. 
Tadalafil također djeluje > 10 000 puta jače na PDE5 nego na enzime PDE7 do PDE10.
- priapsim, a prolonged and possibly painful erection after taking CIALIS (frequency rare). 
- prijapizam, dugotrajna i potencijalno bolna erekcija nakon uzimanja lijeka CIALIS (rijetka učestalost).
With regard to those interaction studies where only the 10 mg tadalafil dose was used, clinically relevant interactions at higher doses cannot be completely ruled out. 
U ispitivanjima interakcija u kojima je tadalafil primijenjen samo u dozi od 10 mg ne mogu se u potpunosti isključiti klinički značajne interakcije pri većim dozama.
Following sexual stimulation CIALIS works by helping the blood vessels in your penis to relax, allowing the flow of blood into your penis. 
Nakon seksualne stimulacije CIALIS pridonosi opuštanju krvnih žila u penisu i tako omogućuje dotok krvi u penis.
CIALIS has been shown to significantly improve the ability of obtaining a hard erect penis suitable for sexual activity. 
Pokazalo se da CIALIS značajno poboljšava sposobnost postizanja i održavanja ukrućenosti dostatne za uspješnu seksualnu aktivnost.
Antidiabetic medicinal products Specific interaction studies with antidiabetic medicinal products were not conducted. 
Antidijabetici Nisu provedena posebna ispitivanja interakcija s antidijabeticima.
5- alpha reductase inhibitors 
Inhibitori 5-alfa reduktaze
Patients with diabetes 
Bolesnici sa šećernom bolešću
The most commonly reported adverse reactions in patients taking CIALIS for the treatment of erectile dysfunction or benign prostatic hyperplasia were headache, dyspepsia, back pain and myalgia, in which the incidences increase with increasing dose of CIALIS. 
Najčešće prijavljena nuspojava u bolesnika koji uzimaju CIALIS za liječenje erektilne disfunkcije ili benigne hiperplazije prostate bile su glavobolja, dispepsija, bolovi u leđima i mialgija, a njihova je incidencija rasla s povećanjem doze lijeka CIALIS.
The randomised, double-blind, placebo-controlled, parallel, 3-arm study of tadalafil was conducted in 331 boys aged 7-14 years with DMD receiving concurrent corticosteroid therapy. 
To randomizirano, dvostruko slijepo, placebom kontrolirano ispitivanje tadalafila s tri paralelne skupine provedeno je u 331 dječaka s DMD-om u dobi od 7 do 14 godina koji su istodobno primali terapiju kortikosteroidima.
Treatment of the signs and symptoms of benign prostatic hyperplasia in adult males. 
Liječenje znakova i simptoma benigne hiperplazije prostate u odraslih muškaraca.
CIALIS is not intended for use by women. 
CIALIS nije namijenjen za primjenu u žena.
Tadalafil (10 mg and 20 mg) did not potentiate the increase in bleeding time caused by acetyl salicylic acid. 
Tadalafil (10 mg i 20 mg) nije potencirao produljenje vremena krvarenja uzrokovano acetilsalicilatnom kiselinom.
Benign prostatic hyperplasia 
Benigna hiperplazija prostate
The effect of PDE5 inhibition on cGMP concentration in the corpus cavernosum is also observed in the smooth muscle of the prostate, the bladder and their vascular supply. 
Učinak inhibicije PDE5 na koncentracije cGMP-a u šupljikavom tijelu također je primijećen u glatkom mišićju prostate, mjehura i krvnih žila koje ih opskrbljuju.
Tadalafil is > 10,000-fold more potent for PDE5 than for PDE1, PDE2, and PDE4, enzymes which are found in the heart, brain, blood vessels, liver, and other organs. 
Tadalafil djeluje > 10 000 puta jače na PDE5 nego na PDE1, PDE2 i PDE4, enzime koji se nalaze u srcu, mozgu, krvnim žilama, jetri i drugim organima.
Studies have confirmed that tadalafil does not inhibit or induce CYP450 isoforms, including CYP3A4, CYP1A2, CYP2D6, CYP2E1, CYP2C9 and CYP2C19. 
Ispitivanja su potvrdila da tadalafil ne inhibira niti inducira izoforme CYP450, uključujući CYP3A4, CYP1A2, CYP2D6, CYP2E1, CYP2C9 i CYP2C19.
A CYP3A4 inducer, rifampicin, reduced tadalafil AUC by 88 %, relative to the AUC values for tadalafil alone (10 mg). 
Rifampicin, induktor CYP3A4, smanjio je AUC tadalafila za 88 % u odnosu na vrijednost AUC-a kod primjene samog tadalafila (10 mg).
The maintenance of the effect was evaluated in an open-label extension to one of the studies, which showed that the improvement in total international prostate symptom score seen at 12 weeks was maintained for up to 1 additional year of treatment with CIALIS 5mg. 
Održavanje učinka procijenjeno je u otvorenom produžetku jednog ispitivanja u kojem je poboljšanje ukupnog rezultata na Međunarodnoj ljestvici simptoma prostatizma primijećeno u 12. tjednu održano tijekom jedne dodatne godine liječenja lijekom CIALIS u dozi od 5 mg.
Although specific interactions have not been studied, other protease inhibitors, such as saquinavir, and other CYP3A4 inhibitors, such as erythromycin, clarithromycin, itraconazole and grapefruit juice should be co-administered with caution as they would be expected to increase plasma concentrations of tadalafil (see section 4.4). 
Iako specifične interakcije nisu ispitane, druge inhibitore proteaze, poput sakvinavira, i druge inhibitore CYP3A4, poput eritromicina, klaritromicina, itrakonazola i soka od grejpa, treba primjenjivati uz oprez jer se očekuje da bi ti lijekovi mogli dovesti do povećanja koncentracije tadalafila u plazmi (vidjeti dio 4.4).
- removal of all or part of the prostate gland in which nerves of the prostate are cut (radical non nerve-sparing prostatectomy). 
- kojima je djelomično ili u cijelosti uklonjena prostata i pritom su prerezani živci prostate (radikalna prostatektomija pri kojoj nisu očuvani živci).
Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). 
Tadalafil je selektivni, reverzibilni inhibitor fosfodiesteraze tipa 5 (PDE5) specifične za ciklički gvanozinfosfat (cGMP).
A. MANUFACTUR ER(S) RESPONSIBLE FOR BATCH RELEASE 
PRILOG II. A. PROIZVOĐAČ(I) ODGOVORAN(NI) ZA PUŠTANJE SERIJE LIJEKA U PROMET
These vascular effects may be complemented by inhibition of bladder afferent nerve activity and smooth muscle relaxation of the prostate and bladder. 
Navedene krvožilne učinke može pratiti inhibicija aktivnosti aferentnog živca u mjehuru i opuštanje glatkih mišića prostate i mjehura.
The maximum dose frequency is once per day. 
Najčešća učestalost doziranja smije biti jednom na dan.
Deutschland Lilly Deutschland GmbH 
Lilly Deutschland GmbH Tel.
This is when the prostate gland gets bigger with age. 
To je stanje u kojem se žlijezda prostata povećava s dobi.
CIALIS improves blood flow to, and relaxes the muscles of, the prostate and bladder which may reduce symptoms of benign prostatic hyperplasia. 
CIALIS poboljšava dotok krvi i opušta mišiće prostate i mjehura, čime se mogu ublažiti simptomi benigne hiperplazije prostate.
If you experience any of the following side effects stop using the medicine and seek medical help immediately: - allergic reactions including rashes (frequency uncommon). 
Ako se pojavi bilo koja od sljedećih nuspojava, prestanite uzimati lijek i odmah zatražite pomoć liječnika: - alergijske reakcije, uključujući osipe (manje česta učestalost).