natgillin/translations-raw huggingface dataset:
Each tablet of Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg contains 300 mg irbesartan and 12.5 mg hydrochlorothiazide. 
Jedna Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg tableta sadrži 300 mg irbesartana i 12,5 mg hidroklorotiazida.
Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg tablets irbesartan/hydrochlorothiazide 
Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg tablete irbesartan/hidroklorotiazid
Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg tablets irbesartan/hydrochlorothiazide 
Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg tablete irbesartan/hidroklorotiazid
EU/1/06/377/011 - 14 tablets EU/1/06/377/012 - 28 tablets EU/1/06/377/029 - 30 tablets EU/1/06/377/013 - 56 tablets EU/1/06/377/014 - 56 x 1 tablets EU/1/06/377/015 - 84 tablets EU/1/06/377/030 - 90 tablets EU/1/06/377/016 - 98 tablets 
EU/1/06/377/011 - 14 tableta EU/1/06/377/012 - 28 tableta EU/1/06/377/029 - 30 tableta EU/1/06/377/013 - 56 tableta EU/1/06/377/014 - 56 x 1 tableta EU/1/06/377/015 - 84 tableta EU/1/06/377/030 - 90 tableta EU/1/06/377/016 - 98 tableta
Package leaflet: Information for the patient Irbesartan Hydrochlorothiazide Zentiva 300 mg/25 mg film-coated tablets irbesartan/hydrochlorothiazide 
Uputa o lijeku: Informacija za bolesnika Irbesartan Hydrochlorothiazide Zentiva 300 mg/25 mg filmom obložene tablete irbesartan/hidroklorotiazid
QUALITATIVE AND QUANTITATIVE COMPOSITION Each film-coated tablet contains 150 mg of irbesartan and 12.5 mg of hydrochlorothiazide. 
KVALITATIVNI I KVANTITATIVNI SASTAV Jedna filmom obložena tableta sadrži 150 mg irbesartana i 12,5 mg hidroklorotiazida.
The trough to peak effects measured by cuff during office visits were 68% and 76% for Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg and Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg, respectively. 
Učinci najniže i najviše koncentracije na sniženje krvnog tlaka nakon primjene lijeka Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg odnosno Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg, prema mjerenjima manžetom za vrijeme kontrolnog pregleda, iznosili su 68% odnosno 76%.
NAME OF THE MEDICINAL PRODUCT Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg film-coated tablets. 
NAZIV LIJEKA Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg filmom obložene tablete
EU/1/06/377/023 - 14 tablets EU/1/06/377/024 - 28 tablets EU/1/06/377/033 - 30 tablets EU/1/06/377/025 - 56 tablets EU/1/06/377/026 - 56 x 1 tablets EU/1/06/377/027 - 84 tablets EU/1/06/377/034 - 90 tablets EU/1/06/377/028 - 98 tablets 
EU/1/06/377/023 - 14 tableta EU/1/06/377/024 - 28 tableta EU/1/06/377/033 - 30 tableta EU/1/06/377/025 - 56 tableta EU/1/06/377/026 - 56 x 1 tableta EU/1/06/377/027 - 84 tableta EU/1/06/377/034 - 90 tableta EU/1/06/377/028 - 98 tableta
NAME OF THE MEDICINAL PRODUCT Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg tablets. 
NAZIV LIJEKA Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg tablete
NAME OF THE MEDICINAL PRODUCT Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg tablets. 
NAZIV LIJEKA Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg tablete
NAME OF THE MEDICINAL PRODUCT Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg film-coated tablets. 
NAZIV LIJEKA Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg filmom obložene tablete
Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg film-coated tablets are supplied in blister packs of 14, 28, 30, 56, 84, 90 or 98 film-coated tablets. 
Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg filmom obložene tablete dostupne su u blister pakiranjima od 14, 28, 30, 56, 84, 90 ili 98 filmom obloženih tableta.
What Irbesartan Hydrochlorothiazide Zentiva looks like and contents of the pack Irbesartan Hydrochlorothiazide Zentiva 300 mg/25 mg film-coated tablets are pink, biconvex, ovalshaped, with a heart debossed on one side and the number 2788 engraved on the other side. 
Kako Irbesartan Hydrochlorothiazide Zentiva izgleda i sadržaj pakiranja Irbesartan Hydrochlorothiazide Zentiva 300 mg/25 mg filmom obložene tablete su bikonveksne, ovalne tablete boje breskve s utisnutom oznakom srca na jednoj i brojem 2788 na drugoj strani.
Each film-coated tablet of Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg contains 150 mg irbesartan and 12.5 mg hydrochlorothiazide. 
Jedna Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg filmom obložena tableta sadrži 150 mg irbesartana i 12,5 mg hidroklorotiazida.
• stomach discoloration, ulcers and focal necrosis of gastric mucosa were observed in few rats in a 6 months toxicity study at irbesartan 90 mg/kg/day, hydrochlorothiazide 90 mg/kg/day, and irbesartan/hydrochlorothiazide 10/10 mg/kg/day. 
promjene funkcije bubrega, karakterizirane blagim porastom razine ureje i kreatinina u serumu kao i hiperplazija/hipertrofija jukstaglomerularnog aparata, što je izravna posljedica interakcije irbesartana s renin-angiotenzinskim sustavom; blago sniženje eritrocitnih parametara (eritrociti, hemoglobin, hematokrit); diskoloracija želuca, ulceracije i fokalna nekroza sluznice želuca primijećene su u nekoliko štakora tijekom šestomjesečnog istraživanja toksičnosti nakon doza od 90 mg/kg/dan irbesartana, 90 mg/kg/dan hidroklorotiazida te kombinacije irbesartana/hidroklorotiazida od 10/10 mg/kg/dan; te lezije nisu zabilježene kod makaki majmuna; smanjenje razine kalija u serumu koje izaziva hidroklorotiazid djelomično je smanjeno kad se hidroklorotiazid davao u kombinaciji s irbesartanom.
Each film-coated tablet of Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg contains 300 mg irbesartan and 12.5 mg hydrochlorothiazide. 
Jedna Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg filmom obložena tableta sadrži 300 mg irbesartana i 12,5 mg hidroklorotiazida.
Side effects reported since the launch of Irbesartan Hydrochlorothiazide Zentiva Some undesirable effects have been reported since marketing of Irbesartan Hydrochlorothiazide Zentiva. 
Neke su nuspojave prijavljene nakon stavljanja lijeka Irbesartan Hydrochlorothiazide Zentiva na tržište.
Lactose monohydrate Hypromellose Titanium dioxide Macrogol 3350 
Film ovojnica: laktoza hidrat hipromeloza titanijev dioksid makrogol 3350 željezov oksid, crveni i crni karnauba vosak
Dosage 
PSUR
What Irbesartan Hydrochlorothiazide Zentiva looks like and contents of the pack Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg film-coated tablets are peach, biconvex, ovalshaped, with a heart debossed on one side and the number 2875 engraved on the other side. 
Kako Irbesartan Hydrochlorothiazide Zentiva izgleda i sadržaj pakiranja Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg filmom obložene tablete su bikonveksne, ovalne tablete boje breskve s utisnutom oznakom srca na jednoj i brojem 2875 na drugoj strani.
• Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg may be administered in patients insufficiently controlled by irbesartan 300 mg or by Irbesartan Hydrochlorothiazide 
Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg može se propisati bolesnicima čiji se krvni tlak ne može na odgovarajući način kontrolirati irbesartanom u dozi od 300 mg ili lijekom Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg.
Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg film-coated tablets irbesartan/hydrochlorothiazide 
Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg filmom obložene tablete irbesartan/hidroklorotiazid
What Irbesartan Hydrochlorothiazide Zentiva looks like and contents of the pack Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg film-coated tablets are peach, biconvex, ovalshaped, with a heart debossed on one side and the number 2876 engraved on the other side. 
Kako Irbesartan Hydrochlorothiazide Zentiva izgleda i sadržaj pakiranja Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg filmom obložene tablete su bikonveksne, ovalne tablete boje breskve s utisnutom oznakom srca na jednoj i brojem 2876 na drugoj strani.
Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg film-coated tablets irbesartan/hydrochlorothiazide 
Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg filmom obložene tablete irbesartan/hidroklorotiazid
Package leaflet: Information for the patient Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg tablets irbesartan/hydrochlorothiazide 
Uputa o lijeku: Informacija za bolesnika Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg tablete irbesartan/hidroklorotiazid
What Irbesartan Hydrochlorothiazide Zentiva looks like and contents of the pack Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg tablets are peach, biconvex, oval-shaped, with a heart debossed on one side and the number 2775 engraved on the other side. 
Kako Irbesartan Hydrochlorothiazide Zentiva izgleda i sadržaj pakiranja Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg tablete su bikonveksne, ovalne tablete boje breskve s utisnutom oznakom srca na jednoj i brojem 2775 na drugoj strani.
Package leaflet: Information for the patient Irbesartan Hydrochlorothiazide Zentiva 150 mg/12.5 mg film-coated tablets irbesartan/hydrochlorothiazide 
Uputa o lijeku: Informacija za bolesnika Irbesartan Hydrochlorothiazide Zentiva 150 mg/12,5 mg filmom obložene tablete irbesartan/hidroklorotiazid
Package leaflet: Information for the patient Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg tablets irbesartan/hydrochlorothiazide 
Uputa o lijeku: Informacija za bolesnika Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg tablete irbesartan/hidroklorotiazid
If you take more Irbesartan Hydrochlorothiazide Zentiva than you should If you accidentally take too many tablets, contact your doctor immediately. 
Ako slučajno uzmete previše tableta, odmah se obratite svome liječniku.
What Irbesartan Hydrochlorothiazide Zentiva looks like and contents of the pack Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg tablets are peach, biconvex, oval-shaped, with a heart debossed on one side and the number 2776 engraved on the other side. 
Kako Irbesartan Hydrochlorothiazide Zentiva izgleda i sadržaj pakiranja Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg tablete su bikonveksne, ovalne tablete boje breskve s utisnutom oznakom srca na jednoj i brojem 2776 na drugoj strani.
PV-Italy@zentiva.com 
PV-Lithuania@zentiva.com
Package leaflet: Information for the patient Irbesartan Hydrochlorothiazide Zentiva 300 mg/12.5 mg film-coated tablets irbesartan/hydrochlorothiazide 
Uputa o lijeku: Informacija za bolesnika Irbesartan Hydrochlorothiazide Zentiva 300 mg/12,5 mg filmom obložene tablete irbesartan/hidroklorotiazid
Each tablet contains: irbesartan 150 mg and hydrochlorothiazide 12.5 mg 
Jedna tableta sadrži 150 mg irbesartana i 12,5 mg hidroklorotiazida
Posology 
publika
120 (60 x 2) capsules (multipack) 
120 (60 x 2) kapsula (višestruko pakiranje)
4866 Unterach am Attersee Austria 
4866 Unterach am Attersee Austrija
There is no known reason for this. 
Razlog tome nije poznat.
In some cases you may need a blood transfusion. 
U nekim slučajevima može biti potrebna transfuzija krvi.
A risk to the newborn/infant cannot be excluded. 
Rizik za novorođenče/dojenče ne može biti isključen.
Blood tests during treatment 
Krvne pretrage tijekom liječenja
If this does occur, it is most likely to occur at the first dose. 
Dođe li do navedenoga, najvjerojatnije će to biti pri primjeni prve doze lijeka.
This can lead to severe bleeding from relatively small injuries such as a small cut. 
To može dovesti do obilnoga krvarenja iz relativno malih rana, poput male porezotine.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. 
Obavijestite svog liječnika ili ljekarnika ako uzimate ili ste nedavno uzimali ili biste mogli uzimati bilo koje druge lijekove.
If you feel tired or weak, do not drive, and do not use any tools or machines. 
Osjećate li se umorno ili slabo, nemojte voziti, niti rukovati alatima ili strojevima.
These patients should be treated with caution. 
Ove bolesnike valja liječiti s oprezom.
This includes spontaneous case reports as well as serious adverse events from ongoing studies. 
Uključeni su spontano prijavljeni slučajevi kao i ozbiljne nuspojave iz studija koje su u tijeku.
This can even be life threatening. 
Ovakvo stanje može biti opasno po život.
If you are an elderly person, you could be more sensitive to nervous system side effects (see the list above under “Warnings and precautions”). 
Ako ste starija osoba, mogli biste biti osjetljiviji na nuspojave živčanog sustava (pogledajte popis iznad pod naslovom „Upozorenja i mjere opreza“).
Infection and infestations 
Infekcije i infestacije
Your dose of Atriance may need to be adjusted. 
Vaša doza lijeka Atriance će možda morati bit prilagođena.
Efficacy and safety were similar for both regimens. 
Djelotvornost i sigurnost primjene u oba slučaja bile su podjednake.
The abnormal high number of white blood cells can appear in the blood and other parts of the body. 
Abnormalno visok broj bijelih krvnih stanica se može pojaviti u krvi i drugim dijelovima tijela.
No case of overdose has been reported. 
Do sada nije prijavljen niti jedan slučaj predoziranja.
• Signs of infection. 
• Znakovi infekcije.
The following convention has been utilised for the classification of frequency: very common (≥ 1/10), common (≥ 1/100 to < 1/10), uncommon (≥ 1/1,000 to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000), and not known (cannot be estimated from the available data). 
Pri klasifikaciji učestalosti nuspojava korištena je sljedeća kategorizacija: vrlo često (≥1/10), često (≥1/100 i <1/10), manje često (≥1/1000 i <1/100), rijetko (≥1/10 000 i <1/1000), vrlo rijetko (<1/10 000), i nepoznato (ne može se procijeniti iz raspoloživih podataka).
Date of first authorisation: 22 August 2007 Date of latest renewal: 16 June 2017 
Datum posljednje obnove odobrenja: 16. lipnja 2017.
Atriance may reduce the number of white blood cells and lower your resistance to infection (including pneumonia). 
Atriance može smanjiti broj bijelih krvnih stanica i umanjiti Vašu otpornost na infekciju (uključujući upalu pluća).
Ask your doctor for advice before taking any medicine. 
Obratite se svom liječniku za savjet prije nego uzmete bilo koji lijek.
Atriance is used to treat patients with: 
Atriance se koristi za liječenje oboljelih od:
The following additional adverse reactions were seen: 
Uočene su sljedeće nuspojave:
38.0 µM.h (39 %), respectively. 
38,0 µM.h (39%).
The potential risk in humans is unknown, however, exposure during pregnancy will likely lead to anomalies and malformations of the foetus. 
Mogući rizik u ljudi nije poznat, no primjena ovoga lijeka tijekom trudnoće vjerojatno bi rezultirala anomalijama i malformacijama ploda.
Your doctor will decide how many treatment cycles are required. 
Vaš liječnik će odlučiti koliko je ciklusa liječenja potrebno.
Nelarabine should not be used during pregnancy unless clearly necessary. 
Nelarabin se ne smije primjenjivati tijekom trudnoće, osim u slučaju kada je to izričito nužno.
Aspartate aminotransferase increased 
Povišenje vrijednosti aspartat aminotransferaze
Do not try and become pregnant/father a child until your doctor advises you it is safe to do so. 
Ne pokušavajte zanijeti/začeti dijete sa svojim partnerom/partnericom dok Vam liječnik ne kaže da to možete učiniti bez štetnih posljedica.
Other medicines and Atriance 
Drugi lijekovi i Atriance
Pharmacotherapeutic group: Antineoplastic agents, antimetabolites, purine analogues, ATC code: L01B B 07 
Farmakoterapijska skupina: Antineoplastici, antimetaboliti, analozi purina, ATK oznaka: L01B B 07
Survival at one year was 29 % [95 % CI: 12 %-45 %]. 
Preživljenje nakon godine dana iznosilo je 29% [95%-ni CI: 12%-45%].
There was a single additional report of biopsy confirmed progressive multifocal leukoencephalopathy in the adult population. 
Samo je jedno dodatno izvješće o slučaju biopsijom potvrđene progresivne multifokalne leukoencefalopatije, zabilježene u odrasloj populaciji.
Your doctor will check for these symptoms regularly during treatment. 
Vaš liječnik će redovito tijekom liječenja provjeravati te simptome.
Based on the pharmacological action of the compound, undesirable effects on fertility are possible. 
Na temelju saznanja o farmakološkom djelovanju ovoga spoja, mogući su neželjeni učinci na plodnost.
You will have an infusion (a drip) once a day on days 1, 3 and 5 of treatment. 
Infuziju (drip) ćete primati jednom dnevno 1., 3. i 5. dana liječenja.
Time to complete response in both classifications of response ranged from 2.9 to 11.7 weeks. 
U oba slučaja, vrijeme do postizanja potpunoga odgovora kretalo se u rasponu od 2,9 do 11,7 tjedana.
• Lowered blood pressure. 
• Sniženi krvni tlak.
What Atriance is and what it is used for 
Što je Atriance i za što se koristi
Two paediatric patients had fatal neurological events. 
U dva pedijatrijska bolesnika došlo je do pojave fatalnih neuroloških događaja.
The dose of Atriance you are given will be based on: 
Doza lijeka Atriance kojom ćete biti liječeni temeljit će se na:
Rarely, it can lead to even more severe bleeding (haemorrhage). 
U rijetkim slučajevima može doći i do težeg, obilnijeg krvarenja (hemoragije).
You/your child (if he/she is being treated) will have an infusion (a drip) once a day for 5 days. 
Vi/ Vaše dijete (ukoliko se ono liječi) dobivat ćete/dobivat će infuziju (drip) jednom dnevno kroz 5 dana zaredom.
Your doctor should perform blood tests regularly during treatment to check for blood problems that have been associated with the use of Atriance. 
Vaš liječnik će provoditi krvne pretrage redovito tijekom liječenja kako bi provjerio krvne probleme koji se povezuju s primjenom lijeka Atriance.
The majority of side effects reported with Atriance were seen in adults, children and adolescents. 
Većina nuspojava povezanih s lijekom Atriance uočena je u odraslih bolesnika, djece i adolescenata.
Some of the side effects were reported more often in adult patients. 
Neke od nuspojava češće su uočavane u odraslih bolesnika.
Peripheral neurological disorders (sensory and motor) 
Poremećaji perifernog živčanog sustava (senzorni i motorički)
Tell your doctor if any of these apply to you. 
Obavijestite svog liječnika ako se nešto od navedenog odnosi na Vas.
This being an approval under exceptional circumstance and pursuant to Article 14(8) of Regulation (EC) No 726/2004, the MAH shall conduct, within the stated timeframe, the following measures: 
Budući da je ovo odobrenje za stavljanje lijeka u promet u iznimnim okolnostima, sukladno članku 14. stavku 8. Uredbe (EZ) br. 726/2004, nositelj odobrenja dužan je unutar navedenog vremenskog roka provesti sljedeće mjere:
Patients must be cautioned that somnolence can affect performance of skilled tasks, such as driving. 
Bolesnike se mora upozoriti da somnolencija može negativno utjecati na sposobnost izvođenja radnji koje iziskuju određene vještine, poput upravljanja vozilima.
• Unintentional rhythmic shaking of one or more limbs (tremors). 
• Nevoljno ritmično drhtanje jednoga ili više ekstremiteta (tremori).
Carcinogenicity testing of nelarabine has not been performed. 
Ispitivanje karcinogenosti nelarabina nije provedeno.
This includes any herbal products or medicines you have bought without a prescription 
To uključuje i biljne lijekove kao i one koje ste nabavili bez recepta.
Atriance has major influence on the ability to drive and use machines. 
Atriance značajno utječe na sposobnost upravljanja vozilima i rada sa strojevima.
Men with partners who are pregnant or could become pregnant should use condoms during treatment with nelarabine and for at least three months following cessation of treatment. 
Muškarci čije su partnerice trudne ili mogu zatrudnjeti moraju koristiti prezervative za vrijeme trajanja liječenja te barem tri mjeseca nakon završetka liječenja nelarabinom.
Atriance is not recommended for pregnant women. 
Primjena lijeka Atriance u trudnica se ne preporučuje.
What Atriance is and what it is used for What you need to know before you are given Atriance How Atriance is given 
Što je Atriance i za što se koristi Što morate znati prije nego počnete primati Atriance
Both sexually active men and women should use effective methods of contraception during treatment with nelarabine. 
Spolno aktivni muškarci i spolno aktivne žene moraju primjenjivati učinkovite metode kontracepcije za vrijeme trajanja liječenja nelarabinom.
Adults (1,500 mg/m N=103 
Odrasli (1500 mg/m N=103
Clinical studies of nelarabine did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger patients. 
Klinička ispitivanja nelarabina nisu uključila dovoljan broj bolesnika u dobi od 65 i više godina, da bi se moglo utvrditi reagiraju li oni na lijek drugačije od mlađih bolesnika.
In an exploratory analysis, increasing age, especially age 65 years and older, appeared to be associated with increased rates of neurological adverse events. 
Eksploracijska analiza je pokazala da je starija životna dob, posebice ona od 65 i više godina, povezana s povišenim stopama neuroloških nuspojava.
• Staff should be trained in how to handle and transfer the medicinal product. 
• Osoblje bi trebalo biti obučeno kako rukovati i prenositi lijek.
Atriance is supplied in packs of 1 vial or 6 vials. 
Atriance je dostupan u pakiranjima s 1 bočicom ili 6 bočica.
Atriance contains nelarabine which belongs to a group of medicines known as antineoplastic agents, used in chemotherapy to kill some types of cancer cells. 
Atriance sadrži nelarabin koji spada u skupinu lijekova poznatih kao antineoplastici koji se koriste u kemoterapiji za uništavanje nekih vrsta stanica raka.
Leukaemia causes an abnormal increase in the number of white blood cells. 
Leukemija uzrokuje abnormalni porast broja bijelih krvnih stanica.
• Swelling of parts of the body due to accumulation of abnormal amounts of fluid (oedema). 
• Oticanje dijelova tijela uslijed nakupljanja abnormalnih količina tekućine (edem).
Your doctor will check for these symptoms regularly during treatment (see also section 4, "Possible side effects"). 
Vaš će liječnik redovito tijekom liječenja provjeravati jeste li razvili ovakve simptome (pogledajte i dio 4, „Moguće nuspojave“).
What you need to know before you are given Atriance 
Što morate znati prije nego počnete primati Atriance
Nine of these 31 patients failed to respond to prior induction (refractory patients). 
Devet njih nije reagiralo na ranije liječenje (rezistentni slučajevi).
• if you (or your child, if he/she is being treated) are allergic to nelarabine or any of the other ingredients of this medicine (listed in section 6). 
• ako ste (odnosno Vaše dijete, ako se ono liječi) alergični/alergično na nelarabin ili neki drugi sastojak ovog lijeka (naveden u dijelu 6).
A doctor or nurse will give you the dose of Atriance as an infusion (a drip). 
Liječnik ili medicinska sestra dat će Vam dozu lijeka Atriance u obliku infuzije (drip).
Nelarabine and ara-G did not significantly inhibit the activities of the major hepatic cytochrome P450 (CYP) isoenzymes CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, or CYP3A4 in vitro. 
U in vitro uvjetima nelarabin i ara-G nisu u značajnoj mjeri inhibirali aktivnost glavnih izoenzima jetrenoga citokroma P450 (CYP) - CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 ili CYP3A4.
Children (650 mg/m N=84 
Djeca (650 mg/m N=84
This medicinal product has been authorised under “exceptional circumstances”. 
Ovaj lijek je odobren pod „iznimnim okolnostima“.
Nelarabine and ara-G are rapidly eliminated from plasma with a half-life of approximately 30 minutes and 3 hours, respectively. 
Nelarabin i ara-G se brzo eliminiraju iz plazme, pri čemu poluvijek nelarabina iznosi približno 30 minuta, a ara-G oko 3 sata.
The effect of nelarabine on fertility in humans is unknown. 
Učinak nelarabina na plodnost u ljudi nije poznat.
Infections and infestations Infection (including but not limited to; sepsis, bacteraemia, pneumonia, fungal infection) 
Infekcije i infestacije Infekcija (uključujući, no ne svodeći se samo na: sepsu, bakterijemiju, upalu pluća, gljivičnu infekciju)
In this case, its cells are called lymphoblasts. 
U ovom slučaju te stanice se zovu limfoblasti.