natgillin/translations-raw huggingface dataset:
Jankovcova 1569/2c 170 00 Prague Czech Republic 
Jankovcova 1569/2c 170 00 Prague Czech Republic adrenalintartarat
Adrenalin 
adrenalintartarat
Warszawskie Zakłady Farmaceutyczne POLFA S.A. ul. 
Warszawskie Zakłady Farmaceutyczne POLFA S.A. ul. Karolkowa 22/24
BIOPROJET PHARMA 9 Rue Rameau 75002 Paris France 
Francuska BIOPROJET PHARMA 9 Rue Rameau
Anapen, oplossing voor injectie microgram/ dosis 
Anapen, oplossing voor injectie mikrograma /doza
Germany PharmaSwiss Ceska republika s.r.o. 
Njemačka PharmaSwiss Ceska republika s.r.o.
Nepipe Junior mikrogram 
Nepipe Junior paranteralno
Epipen 300 mikrogramů 0,3 mg per dose (0,3 mg/0,3 ml) 
Epipen 300 mikrogramů 0,3 mg po dozi (0,3 mg/0,3 ml)
Meda Pharma Hungary Kft. Váci út 91. 
Mađarska Meda Pharma Hungary Kft.
EpiPen 300 microgram/dosis microgram/ dosis 
EpiPen 300 microgram/dosis mikrograma doza
Adrenalină (epinefrină) 
adrenalin (epinefrin)
MEDA Pharma s.r.o. 
Meda Pharma spol. s r. o.
EpiPen Junior 150 microgram/dosis microgram/ dosis 
EpiPen Junior 150 microgram/dosis mikrograma doza
Anapen junior, oplossing voor injectie microgram/ dosis 
Anapen junior, oplossing voor injectie mikrograma doza
Jext 150 microgram, oplossing voor injectie microgram/ dosis 
Jext 150 microgram, oplossing voor injectie mikrograma doza
Jext 300 microgram, oplossing voor injectie microgram/ dosis 
Jext 300 microgram, oplossing voor injectie mikrograma doza
Meda AS Askerveien 61 Postboks 194 1371 Asker Norway 
Norveška Meda AS Askerveien 61
Adrenalin (hydrochloride) 
Germany adrenalin (klorid)
ALK-Abelló AS Bøge Alle 6-8 
Norveška ALK-Abelló AS Bøge Alle 6-8
EPIPEN JUNIOR 150 mikrogramm oldatos injekció előre töltött tollban microgramm /0,3 ml 
EPIPEN JUNIOR 150 mikrogramm oldatos injekció előre töltött tollban mikrograma/ 0,3 ml
0,15 mg per dose (0,15 mg/0,3 ml) 
0,15 mg po dozi (0,15 mg/0,3 ml)
300 mcg / dose 
300 µg / dose
EPIPEN 300 mikrogramm oldatos injekció előre töltött tollban microgramm /0,3 ml 
EPIPEN 300 mikrogramm oldatos injekció előre töltött tollban mikrograma/ 0,3 ml
ANAPEN 300 mikrogramm/0,3 ml oldatos injekció előretöltött fecskendőben microgramm /0,3 ml 
ANAPEN 300 mikrogramm/0,3 ml oldatos injekció előretöltött fecskendőben mikrograma/ 0,3 ml
Epipen microgram/ 0,3 ml 
Epipen mikrograma / 0,3 ml
ANAPEN JUNIOR 150 mikrogramm/0,3 ml oldatos injekció előretöltött fecskendőben microgramm /0,3 ml 
ANAPEN JUNIOR 150 mikrogramm/0,3 ml oldatos injekció előretöltött fecskendőben mikrograma/ 0,3 ml
ALK-Abello A/S Bøge Alle 6-8 B.O.BOX 408 2970 Horsholm Denmark 
ALK-Abello A/S Bøge Alle 6-8 B.O.BOX 408 2970 Horsholm Denmark adrenalintartarat
0,3 mg per dose (0,3 mg/0,3 ml) 
0,3 mg po dozi (0,3 mg/0,3 ml)
Epipen 300 micrograms solution for injection in pre-filled pen micrograms in 0.3ml solution 
Epipen 300 micrograms solution for injection in pre-filled pen mikrograma in 0,3 ml otopine
ALK-Abelló A/S Boge Allé 6-8. 
Francuska ALK-Abelló A/S Boge Allé 6-8.
Anapen Junior microg/0,3 ml 
Anapen Junior mikrograma/ 0,3 ml
Alk Abello A-S Boge Alle 6-8 Hersholm 2970 Denmark 
Alk Abello A-S Boge Alle 6-8 Hersholm 2970 Denmark adrenalintartarat
Adrenaline Ph. Eur. 
Meath Ireland adrenalin Ph. Eur.
Salisbury SP2 0AH Great Britain 
Salisbury SP2 0AH
Anapen Junior 150 micrograms in 0.3ml solution for injection in a pre-filled syringe micrograms/ 0.3ml 
Anapen Junior 150 micrograms in 0.3ml solution for injection in a pre-filled syringe mikrograma /0,3 ml
Mikrogramm /0,3ml 
mikrograma/ 0,3ml
Germany MEDA Pharma GmbH & Co. KG 
Njemačka MEDA Pharma GmbH & Co.
Nepipe mikrogram 
Nepipe paranteralno
Mikrogramm/0,3 ml Injektionslösung in einer Fertigspritze 
Mikrogramm/0,3 ml Injektionslösung in einer Fertigspritze mikrograma /0,3ml
EpiPen 300 micrograme 300 micrograms/ dose 
Germany adrenalin (epinefrin) EpiPen 300 micrograme 300 mikrograma /dose
MEDA PHARMA, SAU Avda. 
Španjolska MEDA PHARMA, SAU Avda. de Castilla, 2
Hersholm 2970 Denmark 
Hersholm 2970 Denmark adrenalintartarat
Adrenaline acid tartrate 
Denmark adrenalintartarat
Jext 300 micrograms solution for injection in pre-filled pen micrograms 
Jext 300 micrograms solution for injection in pre-filled pen
150 mcg / dose 
150 µg / dose
Anapen 150 micrograms/0,3 ml solution for injection in pre-filled syringe micrograms/ 0,3 ml 
Anapen 150 micrograms/0,3 ml solution for injection in pre-filled syringe mikrograma /0,3 ml
Epipen Junior 150 micrograms solution for injection in pre-filled pen micrograms 
Epipen Junior 150 micrograms solution for injection in pre-filled pen
Epipen 300 micrograms solution for injection in pre-filled pen micrograms 
Epipen 300 micrograms solution for injection in pre-filled pen
Anapen 300 micrograms/0,3 ml solution for injection in pre-filled syringe micrograms/ 0,3 ml 
Anapen 300 micrograms/0,3 ml solution for injection in pre-filled syringe mikrograma /0,3 ml
Jext 150 micrograms solution for injection in pre-filled pen micrograms 
Jext 150 micrograms solution for injection in pre-filled pen
Sweden ALK-Abelló A/S Boge Allé 6-8 
Nizozemska ALK-Abelló A/S Boge Allé 6-8
Epinephrine Bitartrate 
EpiPen paranteralno
EpiPen 150 micrograme 150 micrograms/ dose 
Germany adrenalin (epinefrin) EpiPen 150 micrograme 150 mikrograma /dose
Adrenaline tartrate Jext 150 microgramos solución inyectable en pluma precargada 
Jext 150 microgramos solución inyectable en pluma precargada
Anapen microgram/ 0,3 ml 
Anapen mikrograma /0,3 ml
Adrenaline tartrate Jext mikrogram 
Denmark adrenalinhidrogentar tarat (epinefrinhidrogenta rtarat)
Adrenaline tartrate Jext 300 microgramos solución inyectable en pluma precargada 
Jext 300 microgramos solución inyectable en pluma precargada
Anapen 300 micrograms in 0.3ml solution for injection in a pre-filled syringe micrograms/ 0.3ml 
Anapen 300 micrograms in 0.3ml solution for injection in a pre-filled syringe mikrograma /0,3 ml
Anapen 300 micrograms in 0.3ml solution for injection in a pre-filled syringe micrograms in 0.3ml solution 
Anapen 300 micrograms in 0.3ml solution for injection in a pre-filled syringe mikrograma in 0,3 ml otopine
Epipen 150 micrograms solution for injection in pre-filled pen micrograms 
Epipen 150 micrograms solution for injection in pre-filled pen
Alk Abello A/S Boge Alle 6-8 2970 Horsholm Denmark 
Alk Abello A/S Boge Alle 6-8 2970 Horsholm Denmark epinefrin hidrogentartarat
Anapen microg/0,3 ml 
Anapen mikrograma/ 0,3 ml
1 in 1000 Solution for injection Intramuscular/subcu taneous use 
1 in 1000 otopina za injekciju u mišić/ potkožno
Lincoln Medical limited Unit 8 Wilton Business Centre Wilton 
Norveška Lincoln Medical limited Unit 8 Wilton Business Centre Wilton
Denmark Lincoln Medical Ltd Unit 8 Wilton Business Centre 
Lincoln Medical Ltd Unit 8 Wilton Business Centre
0,3 mg/dose Solution for injection Intramuscular use 
0,3 mg/doza otopina za injekciju u mišić
Adrenaline tartrate Emerade 500 micrograms solution for injection in pre-filled pen micrograms 
Emerade 500 micrograms solution for injection in pre-filled pen
0,15 mg Solution for injection Intramuscular use 
0,15 mg otopina za injekciju u mišić
EpiPen jr mikrogram 
EpiPen jr paranteralno
150 mikrog Solution for injection in pre-filled pen 
Emerade 150 micrograms solution for injection in pre-filled pen
0,15 mg/3ml Solution for injection Intramuscular use 
0,15 mg/3ml otopina za injekciju u mišić
Adrenaline tartrate Emerade 300 micrograms solution for injection in pre-filled pen micrograms 
Emerade 300 micrograms solution for injection in pre-filled pen
Adults, including the elderly 
Odrasli, uključujući starije osobe
Talk to your doctor immediately if these symptoms become severe. 
Odmah obavijestite svog liječnika ako ti simptomi postanu teški.
Date of first authorisation: 22 March 2018 
Datum prvog odobrenja: 22. ožujka 2018.
NS: not significant 
NZ: nije značajno
Treatment was discontinued on study exit (Day 365). 
Liječenje je prekinuto na dan izlaska iz ispitivanja (365. dan).
Not known (frequency cannot be estimated from the available data). 
Nepoznato (učestalost se ne može procijeniti iz dostupnih podataka)
• Do not take this starting dose for more than three days. 
• Nemojte uzimati tu početnu dozu dulje od tri dana.
• Try to take Lokelma at the same time each day. 
• Pokušajte uzimati lijek Lokelma svaki dan u isto vrijeme.
The suspension can be taken with or without food. 
Suspenzija se može uzeti s hranom ili bez nje.
Do not give this medicine to children and adolescents under 18 years of age. 
Ovaj lijek se ne smije davati djeci i adolescentima mlađima od 18 godina.
• Then take the next dose as usual at your normal time. 
• Zatim uzmite sljedeću dozu u uobičajeno vrijeme.
The risk of interaction with X-rays 
Rizik od interakcije s rendgenskim zrakama
• The medicine takes one to two days to work. 
• Lijeku je potreban jedan ili dva dana da ostvari svoj učinak.
Therefore, the subject was eligible for the Correction Phase ITT Population; however, the time point was excluded from the analysis. 
Stoga je taj ispitanik mogao biti uključen u ITT populaciju korekcijske faze; međutim, ta je vremenska točka isključena iz analize.
If you take more Lokelma than you should: 
Ako uzmete više lijeka Lokelma nego što ste trebali:
Do not use this medicine during pregnancy because there is no information on its use in pregnancy. 
Nemojte uzimati ovaj lijek tijekom trudnoće jer nema informacija o njegovoj primjeni u trudnoći.
• You can take this medicine with or without meal. 
• Ovaj lijek možete uzimati s hranom ili bez nje.
Hypokalaemia may be observed (see section 4.8). 
Može se pojaviti hipokalijemija (vidjeti dio 4.8).
If you take more of this medicine than you should, talk to a doctor straight away. 
Ako uzmete više ovog lijeka nego što ste trebali, odmah se obratite liječniku.
• This is to make sure you are getting the correct dose. 
• To je zato da budu sigurni da dobivate točnu dozu lijeka.
Long term exposure 
Dugoročna izloženost
The powder will not dissolve. 
Prašak se neće otopiti.
• Rinse the glass with more water and drink it all up to take all the medicine. 
• Isperite čašu s još vode i popijte sve da biste uzeli sav lijek.
Your doctor or nurse will check your blood potassium level when you start taking this medicine: 
Vaš liječnik ili medicinska sestra provjeravat će Vam razinu kalija u krvi kada počnete uzimati ovaj lijek:
• diuretics (medicines that increase urine production) 
• diuretici (lijekovi koji povećavaju stvaranje mokraće)
The safety and efficacy of Lokelma in children and adolescents (< 18 years) have not been established. 
Sigurnost i djelotvornost lijeka Lokelma kod djece i adolescenata (< 18 godina) nisu ustanovljene.
What Lokelma is and what it is used for 
Što je Lokelma i za što se koristi
If a patient misses a dose they should be instructed to take the next usual dose at their normal time. 
Ako bolesnik propusti uzeti dozu, treba ga uputiti da uzme sljedeću dozu u uobičajeno vrijeme.
If the powder settles, the water should be stirred again. 
Ako se prašak nataloži na dnu, treba ponovno promiješati vodu.
Lokelma 10 g three times daily (N=749) 
Lokelma 10 g triput na dan (N=749)
The white powder will settle in the glass quickly. 
Bijeli prašak brzo će se početi taložiti na dnu čaše.
Do not reduce the dose of this medicine or stop taking it without talking to the doctor who prescribed it. 
Nemojte smanjiti dozu ovog lijeka niti prekinuti njegovu primjenu bez prethodnog razgovora s liječnikom koji Vam ga je propisao.
The sachets are supplied in a carton containing 3, 28 or 30 sachets. 
Vrećice dolaze u kutiji koja sadrži 3, 28 ili 30 vrećica.
41 7.6 49 7.2 NS 
41 7,6 49 7,2 NZ
As a precautionary measure, it is preferable to avoid the use of Lokelma during pregnancy. 
Kao mjera opreza, poželjno je izbjegavati primjenu lijeka Lokelma tijekom trudnoće.
• Stir well and drink the tasteless liquid straight away. 
• Dobro promiješajte i odmah popijte tekućinu bez okusa.
Intestinal perforation 
Intestinalna perforacija
Long-term exposure Clinical trials with Lokelma have not included exposure longer than one year. 
Dugoročna izloženost Klinička ispitivanja lijeka Lokelma nisu uključivala izlaganje dulje od jedne godine.
• The powder does not dissolve and the liquid appears cloudy. 
• Prašak se ne otapa, a tekućina izgleda mutno.
When normokalaemia is achieved, the maintenance regimen should be followed (see below). 
Nakon što se postigne normokalijemija, treba prijeći na režim održavanja (vidjeti u nastavku).
Maintenance phase 
Faza održavanja
Do not take any more until you have spoken to a doctor. 
Nemojte više uzimati lijek dok ne porazgovarate s liječnikom.
Powder for oral suspension. 
Prašak za oralnu suspenziju.
To open, cut across top. 
Za otvaranje, odrežite vrh vrećice.
Hyperkalaemia means that there is a high level of potassium in the blood. 
Hiperkalijemija znači da je prisutna visoka razina kalija u krvi.
The entire contents of the sachet should be emptied in a drinking glass containing approximately 45 ml of water and stirred well. 
Cijeli sadržaj vrećice treba istresti u čašu koja sadrži približno 45 ml vode i dobro ga promiješati.
No dietary restrictions were imposed; patients were instructed to continue their usual diet without any specified alterations. 
Nisu nametnuta nikakva prehrambena ograničenja; bolesnici su dobili naputak da se nastave hraniti kao i obično, bez ikakvih specifičnih promjena.
• you have sudden or severe pain in your abdomen as this may be a sign of a problem that is observed with other medications that work in the gastrointestinal tract. 
• Imate iznenadnu ili jaku bol u trbuhu jer to može biti znak problema koji je zapažen kod drugih lijekova koji djeluju u probavnom sustavu.
Pack sizes: 3, 28 or 30 sachets 
Veličine pakiranja: 3, 28 ili 30 vrećica.
If normokalaemia is not achieved after 72 hours of treatment, other treatment approaches should be considered. 
Ako se normokalijemija ne postigne nakon 72 sata liječenja, potrebno je razmotriti druge terapijske opcije.
Lokelma is indicated for the treatment of hyperkalaemia in adult patients (see section 4.4 and 5.1). 
Lokelma je indicirana za liječenje hiperkalijemije kod odraslih bolesnika (vidjeti dijelove 4.4 i 5.1).
No consistent effect on systolic and diastolic blood pressure has been observed. 
Nije primijećen dosljedan učinak na sistolički i dijastolički krvni tlak.
Due to the open label study design, a causal relationship between these events and Lokelma cannot be definitively established. 
S obzirom na otvoreni dizajn ispitivanja ne može se definitivno utvrditi uzročna povezanost između tih događaja i lijeka Lokelma.
Typically, normokalaemia is achieved within 24 to 48 hours. 
Normokalijemija se obično postiže unutar 24 do 48 sati.
The following convention was used for frequency of adverse reactions: Very common (≥ 1/10); Common (≥ 1/100 to < 1/10); Uncommon (≥ 1/1,000 to < 1/100); Rare (≥ 1/10,000 to < 1/1,000); Very rare (< 1/10,000), not known (cannot be estimated from the available data). 
Za određivanje učestalosti nuspojava koristile su se sljedeće kategorije: vrlo često (≥ 1/10); često (≥ 1/100 i < 1/10); manje često (≥ 1/1000 i < 1/100); rijetko (≥ 1/10 000 i < 1/1000); vrlo rijetko (< 1/10 000); nepoznato (ne može se procijeniti iz dostupnih podataka).
Since intestinal perforation has been reported with polymers that act in the gastrointestinal tract, specific attention should be paid to signs and symptoms related to intestinal perforation. 
S obzirom na to da je intestinalna perforacija prijavljena kod polimera koji djeluju u gastrointestinalnom traktu, potreban je poseban oprez sa znakovima i simptomima povezanima sa intestinalnom perforacijom.
Maintenance (day) 
Održavanje (dan)
What Lokelma contains 
Što Lokelma sadrži
In addition, clinical studies have shown it not to be systemically absorbed. 
Uz to, klinička su ispitivanja pokazala da ne dolazi do njegove sistemske apsorpcije.
Tell your doctor or nurse if you experience any of the following: Common side effects (may affect up to 1 in 10 people). 
Obavijestite liječnika ili medicinsku sestru ako primijetite bilo koju od sljedećih nuspojava: Česte nuspojave (mogu se javiti u do 1 na 10 osoba):
The tasteless liquid should be drunk while still cloudy. 
Tekućinu bez okusa treba popiti dok je još mutna.
Oedema related events 
Događaji povezani s edemom
Correction phase 
Korekcijska faza
While you are taking Lokelma, tell your doctor or nurse if • you need to have an X-ray, as Lokelma may affect the interpretation of the results. 
Dok uzimate lijek Lokelma, obavijestite svog liječnika ili medicinsku sestru ako • trebate ići na rendgensko snimanje, jer lijek Lokelma može utjecati na tumačenje rezultata.
• Do not take a maintenance dose of more than 10 g once a day. 
• Nemojte uzimati dozu održavanja višu od 10 g jedanput na dan.
What Lokelma is and what it is used for What you need to know before you take Lokelma How to take Lokelma 
Što je Lokelma i za što se koristi Što morate znati prije nego počnete uzimati lijek Lokelma Kako uzimati lijek Lokelma
If this happens, stir the liquid again and drink it all up. 
U tom slučaju ponovno promiješajte tekućinu i popijte sve.
Lokelma lowers the high levels of potassium in your body and helps to keep it at a normal level. 
Lokelma snizuje visoke razine kalija u tijelu i pomaže ih održati unutar normalnih vrijednosti.
Median time to normokalaemia was 2.2 hours with 66% of patients achieving normokalaemia at 24 hours and 88% at 48 hours. 
Medijan vremena do nastupa normokalijemije iznosio je 2,2 sata; 66% bolesnika postiglo je normokalijemiju nakon 24 sata, a 88% njih nakon 48 sati.
• renin inhibitors such as aliskiren (for high blood pressure) 
• inhibitori renina, kao što je aliskiren (za visok krvni tlak)
1.25 g three times daily 
1,25 g triput na dan
In addition, two open-label maintenance studies tested long-term safety of Lokelma. 
Nadalje, u dva otvorena ispitivanja terapije održavanja ocjenjivala se dugoročna sigurnost lijeka Lokelma.
In particular, tell them about any medicines which can change your blood potassium levels because your dose of Lokelma may need to be changed. 
Osobito je važno da im kažete ako uzimate bilo koji lijek koji može promijeniti razinu kalija u krvi jer će možda trebati promijeniti dozu lijeka Lokelma.
Pharmacotherapeutic group: Drugs for treatment of hyperkalaemia and hyperphosphatemia, ATC code: V03AE10 
Farmakoterapijska skupina: Lijekovi za liječenje hiperkalijemije i hiperfosfatemije, ATK oznaka: V03AE10
There are no other ingredients in this medicine. 
Ovaj lijek nema drugih sastojaka.
Also, tell your doctor or nurse if you are taking any of the following: 
Također, obavijestite liječnika ili medicinsku sestru i ako uzimate neki od sljedećih lijekova:
If patients are still hyperkalaemic after 48 hours of treatment, the same regimen can be continued for an additional 24 hours. 
Ako je hiperkalijemija prisutna i nakon 48 sati liječenja, isti se režim može nastaviti primjenjivati još 24 sata.
In an environment where other factors affecting renin and aldosterone were not controlled, Lokelma demonstrated a dose-independent change in mean serum aldosterone levels (range: -30% to -31%) compared with the placebo group (+14%). 
U uvjetima u kojima drugi faktori koji utječu na renin i aldosteron nisu bili kontrolirani, Lokelma je dovela do o dozi neovisne promjene srednje vrijednosti serumskih razina aldosterona (raspon: od -30% do -31%) u usporedbi sa skupinom koja je primala placebo (+14%).
• Your doctor may decide that you need more (10 g once a day) or less than this (5 g every other day). 
• Vaš će liječnik možda odlučiti da trebate uzimati više (10 g jedanput na dan) ili manje od toga
Sodium zirconium cyclosilicate starts reducing serum potassium concentrations as soon as 1 hour after ingestion and normokalaemia can be achieved typically within 24 to 48 hours. 
Natrijev cirkonijev ciklosilikat započinje snižavati serumsku koncentraciju kalija već 1 sat nakon ingestije i normokalijemija može biti postignuta obično unutar 24 do 48 sati.
• you start to have a build up of fluid in the tissues, leading to swelling anywhere in your body (usually in the feet and ankles). 
• ako Vam se u tkivima počne nakupljati tekućina, što dovodi do oticanja bilo kojeg dijela tijela (obično stopala i gležnjeva).
• Treatment may be stopped if your blood potassium level becomes too low. 
• Liječenje se može prekinuti ako razina kalija u krvi postane preniska.
Among those patients using RAAS inhibitors at baseline, 89% did not discontinue RAAS inhibitor therapy, 74% were able to maintain the same dose during the maintenance phase and among those not on RAAS inhibitors at baseline, 14% were able to initiate this therapy. 
Među bolesnicima koji su na početku ispitivanja uzimali RAAS inhibitore, njih 89% nije prekinulo terapiju RAAS inhibitorima, a njih 74% moglo je nastaviti primati istu dozu tijekom faze održavanja, dok je među onima koji na početku ispitivanja nisu uzimali RAAS inhibitore, njih 14% moglo započeti tu terapiju.
Due to these factors and its insolubility, no in vivo or in vitro studies have been performed to examine its effect on cytochrome P450 (CYP450) enzymes or transporter activity. 
S obzirom na navedene faktore i netopljivost lijeka, nisu provedena ispitivanja in vivo ni in vitro koja bi ocijenila njegov učinak na enzime citokroma P450 (CYP450) ili aktivnost prijenosnika.
Serum potassium levels should be monitored regularly during treatment. 
Razine kalija u serumu treba redovito kontrolirati tijekom liječenja.
Lokelma is used to treat hyperkalaemia in adults. 
Lokelma se koristi za liječenje hiperkalijemije kod odraslih osoba.
These five studies included 1760 patients given doses of Lokelma; 507 exposed for at least 360 days. 
U tih je pet ispitivanja bilo uključeno 1760 bolesnika koji su primali lijek Lokelma; 507 njih bilo je izloženo lijeku tijekom najmanje 360 dana.
The risk for intestinal perforation with the use of Lokelma is currently unknown. 
Rizik od intestinalne perforacije kod primjene lijeka Lokelma je trenutno nepoznat.
No statistically significant changes in urinary sodium excretion were observed. 
Nisu primijećene statistički značajne promjene u izlučivanju natrija mokraćom.
If any of the above apply to you (or you are not sure), tell your doctor, pharmacist or nurse before taking this medicine. 
Ako se bilo što od navedenoga odnosi na Vas (ili ako niste sigurni), razgovarajte sa svojim liječnikom, ljekarnikom ili medicinskom sestrom prije nego uzmete ovaj lijek.
Starting dose - to lower your high potassium level to normal: 
Početna doza - za snižavanje visoke razine kalija do normalnih vrijednosti:
There were no studies conducted to investigate the pharmacodynamics when sodium zirconium cyclosilicate is administered with or without food. 
Nijedno ispitivanje nije provedeno kako bi se istražila farmakodinamika kada se natrijev cirkonijev ciklosilikat uzima s hranom ili bez nje.
• If you forget to take a dose of this medicine, skip the missed dose. 
• Ako ste zaboravili uzeti ovaj lijek, preskočite propuštenu dozu.
The safety profile of Lokelma was evaluated in clinical trials involving 1760 patients with 507 patients exposed for one year. 
Sigurnosni profil lijeka Lokelma ocjenjivao se u kliničkim ispitivanjima koja su uključivala 1760 bolesnika, od kojih je njih 507 bilo izloženo lijeku tijekom jedne godine.
The adverse reactions identified from controlled trials are shown in Table 1. 
Nuspojave utvrđene u kontroliranim ispitivanjima prikazane su u Tablica
Do not use this medicine after the expiry date which is stated on the carton and the sachet after ‘EXP'. 
Ovaj lijek se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na kutiji i vrećici iza oznake „Rok valjanosti“ ili „EXP“.
Monitoring frequency will depend upon a variety of factors including other medications, progression of chronic kidney disease and dietary potassium intake. 
Učestalost kontrola ovisit će o različitim faktorima, uključujući druge lijekove, progresiju kronične bubrežne bolesti i unos kalija putem hrane.