natgillin/translations-raw huggingface dataset:
The acetylation process is not genetically determined as is the case for isoniazid. 
Proces acetilacije nije genetički utvrđen kao što je to u slučaju izoniazida.
The recommended schedule is 4 g every 8 hours. 
Preporučena doza je 4 g svakih 8 sati.
If you forget to take a dose of GRANUPAS 
Ako ste zaboravili uzeti dozu lijeka GRANUPAS
Regular monitoring of the thyroid function is indicated for all people living with HIV. 
Redovito praćenje funkcije štitnjače indicirano je za sve osobe koje imaju HIV.
PARTICULARS TO APPEAR ON THE OUTER PACKAGING CARTON BOX 
PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU KARTONSKA KUTIJA
The optimal dose regimen in children is uncertain. 
Optimalni dozni režim u djece je promjenljiv.
In a single dose (4 grams) pharmacokinetic study in healthy adult volunteers (N=11) the initial time to a 2 µg/mL serum level of aminosalicylic acid was 2 hours with a range of 45 minutes to 24 hours; the median time to peak was 6 hours with a range of 1.5 to 24 hours; the mean peak level was 20 µg/mL with a range of 9 to 35µg/mL: a level of 2 µg/mL was maintained for an average of 8 hours with a range of 5 to 9.5 a level of 1 µg/mL was maintained for an average of 8.8 hours with a range of 6 to 11.5 hours. 
U farmakokinetičkom ispitivanju jedne doze (4 grama) u zdravih odraslih dobrovoljaca (N=11), početno vrijeme za postizanje 2 µg/mL razine aminosalicilatne kiseline u serumu bilo je 2 sata s rasponom od 45 minuta do 24 sata; medijan do postizanja vršne koncentracije bio je 6 sati s rasponom od 1,5 do 24 sata; srednja vrijednost vršne koncentracije iznosila je 20 µg/mL s rasponom od 9 do 35µg/mL: razina od 2µg/mL održana je prosječno 8 sati s rasponom od 5 do 9,5 sati, razina od 1 µg/mL održana je prosječno 8,8 sati s rasponom od 6 do 11,5 sati.
The dosage is doubled every 2 days until reaching a total of 1 gram after which the dosage is divided to follow the regular schedule of administration. 
Doza se zatim udvostručuje svaka 2 dana sve dok se ne postigne ukupna doza od 1 grama, nakon čega se doza treba podijeliti kako bi se pratio redoviti raspored primjene.
The recommended total dose per day is 150 mg for each kg of body weight. 
Preporučena ukupna doza na dan iznosi 150 mg po kilogramu tjelesne mase.
See section 4.2 for posology adjustments for desensitization. 
Vidjeti dio 4.2 o prilagodbi doziranja za potrebe desenzibilizacije.
• elevated liver enzymes, 
• povišene vrijednosti jetrenih enzima,
Triglyceride absorption is always normal. 
Apsorpcija triglicerida je uvijek očuvana.
• Diphenylhydramine (for allergic reactions) 
difenilhidramin (za alergijske reakcije)
What GRANUPAS is and what it is used for What you need to know before you take GRANUPAS How to take GRANUPAS 
Što je GRANUPAS i za što se koristi Što morate znati prije nego počnete uzimati GRANUPAS Kako uzimati GRANUPAS
Use of GRANUPAS is not recommended in newborn babies (under 28 days of age). 
Djeca Primjena lijeka GRANUPAS ne preporučuje se u novorođenčadi (mlađe od 28 dana).
• reduced ability to absorb nutrients from food ulcer, 
• smanjena sposobnost apsorpcije hranjivih tvari iz hrane,
• To measure the dose: o Lines on the spoon indicate the amount (in milligrams of para-aminosalicylic acid). 
• Za mjerenje doze: o Linije na žlici označavaju količinu (u miligramima paraaminosalicilatne kiseline).
Plasma protein binding is about 50 to 60%, the kinetic distribution has a half-life of 0.94 hours and a volume of distribution of 1.001 L/kg. 
Vezanje za proteine plazme je 50 do 60%, kinetička distribucija ima poluvijek od 0,94 sati i volumen distribucije od 1,001 L/kg.
• red spots on the skin, 
• crvene mrlje na koži,
What GRANUPAS looks like and contents of the pack 
Kako GRANUPAS izgleda i sadržaj pakiranja
Uncommon side effects (may affect more than 1 in 1,000 people): • loss of appetite (anorexia). 
Manje česte (mogu se pojaviti u više od 1 na 1 000 osoba): • gubitak apetita (anoreksija)
• reduction of the ability of red blood cells to release oxygen 
• smanjenje sposobnosti crvenih krvnih stanica da otpuštaju kisik
For infants, children and adolescents the dosage will be adapted to the patient's weight at 150 mg/kg per day, divided in two intakes. 
Za dojenčad, djecu i adolescente, doza se treba prilagoditi prema tjelesnoj težini bolesnika, i to 150 mg/kg na dan, podijeljeno u dvije dnevne doze.
There is no experience with overdose in humans. 
Nema slučajeva predoziranja u ljudi.
Swallow the granules whole. 
Progutajte cijele granule.
The recommended dose for adults is 1 sachet three times a day, with a schedule of 1 sachet every 8 hours. 
Preporučena doza za odrasle osobe je 1 vrećica tri puta na dan, i to 1 vrećica svakih 8 sati.
Lucane Pharma 172 rue de Charonne 75011 Paris France 
Proizvođač Lucane Pharma 172 rue de Charonne 75011 Paris Francuska
Pharmacotherapeutic group: Antimycobacterials, drugs for treatment of tuberculosis, ATC code: J04AA01 
Farmakoterapijska skupina: Antimikobakterijski lijekovi, lijekovi za liječenje tuberkuloze, ATK oznaka: J04AA01
Your physician may need to start with a lower dose to prevent possible side effects. 
Vaš liječnik će možda i započeti liječenje s manjom dozom kako bi se spriječile nuspojave.
• crystals in urine. 
• kristali u mokraći.
The data available from a rat embryofoetal development study, where animals were given sodium aminosalicylate (3.85 to 385 mg/kg) were limited. 
Podaci dostupni iz ispitivanja embrio-fetalnog razvoja u štakora, u kojima je životinjama davan natrijev aminosalicilat (3,85 do 385 mg/kg), bili su ograničeni.
• if you are allergic to para-aminosalicylic acid or any of the other ingredients of this medicine (listed in section 6). 
• ako ste alergični na paraaminosalicilatnu kiselinu ili neku pomoćnu tvar ovog lijeka (navedenu u dijelu 6).
GRANUPAS is not recommended during pregnancy and should only be used if advised by your physician. 
GRANUPAS se ne preporučuje tijekom trudnoće i smije se uzimati samo ako vam je to savjetovao liječnik.
The patient must be monitored carefully during the first three months of therapy and treatment must be discontinued immediately at the first sign of a rash, fever or other premonitory signs of intolerance. 
Bolesnici se moraju pažljivo pratiti tijekom prva tri mjeseca terapije, a liječenje se mora odmah prekinuti na prvi znak osipa, vrućice ili ostalih najavljujućih simptoma netolerancije.
• disturbance of gait and equilibrium. 
• poremećaji hoda i ravnoteže.
• yellowing of skin or eyes (jaundice), 
• žutilo kože ili očiju (žutica),
GRANUPAS is unlikely to affect your ability to drive any vehicle and use machines. 
Nije izgledno da GRANUPAS utječe na Vašu sposobnost upravljanja vozilima i strojevima.
The medicinal product should be swallowed immediately after mixing with orange juice, tomato juice, apple sauce and yogurt whilst the granules are intact. 
Lijek se treba progutati odmah nakon miješanja sa sokom od naranče, sokom od rajčice, kašicom od jabuke ili jogurtom dok su granule još uvijek cijele.
• weight loss. 
• gubitak tjelesne težine.
If you experience any of these symptoms, you must contact to your doctor immediately. 
Ako primijetite bilo koji od navedenih simptoma, morate se odmah obratiti svom liječniku.
to < 1/100), rare (≥ 1/10,000 to < 1/1,000), very rare (< 1/10,000), not known (cannot be estimated from the available data). 
Učestalost je definirana kao vrlo često (≥ 1/10), često (≥ 1/100 i < 1/10), manje često (≥ 1/1000 i < 1/100), rijetko (≥ 1/10 000 i < 1/1000), vrlo rijetko (< 1/10 000), nepoznato (ne može se procijeniti iz dostupnih podataka).
The dose in infants, children and adolescents will be calculated by your doctor based on the patient's body weight. 
Liječnik će izračunati dozu za dojenčad, djecu i adolescente na temelju tjelesne težine bolesnika.
• If some granules are left in the glass, add some more juice and drink straight away. 
Ako granule ostanu na dnu čaše, dodajte još malo soka i odmah popijte.
It should be drunk at once ensuring that the granules are not left in the glass. 
Sadržaj čaše treba popiti odjednom pazeći da granule nisu ostale u čaši.
A dosing spoon is provided to measure small doses below 4 g for young children. 
S lijekom se isporučuje i žlica za doziranje kako bi se omogućilo mjerenje doza manjih od 4g za mlađu djecu.
Cutaneous hypersensitivity reactions were also frequent as well as adverse reactions related to the nervous system. 
Kožne reakcije preosjetljivosti također su česte kao i nuspojave povezane sa živčanim sustavom.
Talk to your doctor or pharmacist before taking GRANUPAS 
Obratite se svom liječniku ili ljekarniku prije nego uzmete GRANUPAS
Results indicate that para-aminosalicylic acid was considered not to have produced any clastogenic effect in mice treated at non-toxic dose levels (examined 24 hours after 2 daily administrations of 312.5 to 1250 mg/kg). 
Rezultati pokazuju da se paraaminosalicilatna kiselina ne smatra uzrokom bilo kojeg klastogenog učinka u miševa koji su bili tretirani netoksičnim dozama (ispitivani u trajanju od 24 sata nakon 2 dana primjene od 312,5 do 1250 mg/kg).
o Put granules directly into the spoon. 
o Stavite granule izravno na žlicu.
1244 RL Ankeveen The Netherlands 
1244 RL Ankeveen Nizozemska
It is important that you do not dissolve, crush or chew the granules as they may not absorb properly and may cause stomach ache or bleeding. 
Važno je da ne otapate, ne drobite i ne žvačete granule jer to može dovesti do slabe apsorcije i uzrokovati bol u želucu ili krvarenje.
It inhibits the onset of bacterial resistance to streptomycin and isoniazid. 
Inhibira razvoj bakterijske rezistencije na streptomicin i izoniazid.
Pleural or synovial fluid concentrations are approximately equal to plasma. 
Koncentracije u pleuralnoj ili sinovijskoj tekućine otprilike su jednake onima u plazmi.
Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis. 
Aminosalicilatna kiselina je bakteriostatik protiv Mycobacterium tuberculosis.
Each box contains 30 sachets. 
Jedna kutija sadrži 30 vrećica.
The drug does not cross the blood brain barrier in patients unless the meninges are inflamed, when the concentration of para-aminosalicylic acid in cerebrospinal fluid is about 10 to 50% of the plasma. 
Lijek ne prolazi kroz krvno-moždanu barijeru u bolesnika, osim ako moždana ovojnica nije upaljena, kada koncentracija paraaminosalicilatne kiseline u cerebrospinalnoj tekućini iznosi otprilike 10 do 50% plazmatske koncentracije.
Cellulose, microcrystalline 
Celuloza, mikrokristalična
• if you have liver problems or mild or moderate kidney disease 
• ako imate problema s jetrom ili blagu ili umjerenu bolest bubrega
Bone defects were observed at 77 mg/kg only.and increased foetal weight was noted at the other doses. 
Defekti kostiju uočeni su samo pri 77 mg/kg, a povećana težina fetusa uočena je pri višim dozama.
• if you have a stomach ulcer 
• ako imate čir želuca
• soft stools, 
• mekane stolice,
The lack of a dose-response relationship suggests that the findings are not of clinical relevance, but it is noted that the findings were observed at doses below those proposed clinically. 
Nedostatak odnosa doze i odgovora ukazuje da navedeni rezultati nisu klinički značajni, no isti su uočeni pri dozama manjima od klinički predloženih doza.
The cumulative excretion of para-aminosalicylic after 24 hours is 84% of an oral dose of 4 g, 21% as para-aminosalicylic acid and 63% as the acetylated form. 
Kumulativno izlučivanje paraaminosalicilatne kiseline nakon 24 sata iznosi 84% oralne doze od 4 g, i to 21% u obliku paraaminosalicilatatne kiseline i 63% u acetiliranom obliku.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements. 
Neiskorišteni lijek ili otpadni materijal potrebno je zbrinuti sukladno nacionalnim propisima..
As there are no adequate and well controlled studies of para- aminosalicylic acid in humans, para-aminosalicylic acid should be given to a pregnant woman only if clearly needed. 
Budući da ne postoje primjerena i dobro kontrolirana ispitivanja paraaminosalicilatne kiseline u ljudi, paraaminosalicilatna kiselina se smije primjenjivati u trudnica samo ako je to neophodno.
During the first 3 months of your treatment with GRANUPAS, you must be attentive to any sign of allergic reaction (for example skin eruption, itchy red spots on the skin, itching, rash, watery or itchy eyes or stuffy nose) or hepatitis (for example fever, fatigue, dark urine, pale stool, abdominal pain, yellow skin and eyes). 
Tijekom prva 3 mjeseca liječenja lijekom GRANUPAS morate obratiti pozornost na bilo kakve znakove alergijske reakcije (poput izbijanja kožnih promjena, crvenih mrlja na koži koje svrbe, svrbeža, osipa, suzenja očiju ili svrbeža u očima te začepljenog nosa) ili hepatitisa (poput vrućice, umora, tamnog urina, svijetle stolice, boli u trbuhu, žute kože i očiju).
The first symptoms usually appear within three months of the start of therapy with a rash as the most common adverse reaction followed by fever and much less frequently by gastrointestinal disturbances of anorexia, nausea or diarrhoea. 
Prvi se simptomi najčešće pojavljuju unutar tri mjeseca od početka terapije, i to kao osip koji je najčešća nuspojava zatim vrućica i mnogo rjeđe gastrointestinalni poremećaji anoreksija, mučnina ili proljev.
Gastro-resistant granules The granules are small off white/ light brown coloured approximately 1.5 mm diameter. 
Granule su male prljavo bijele / svjetlo smeđe boje promjera otprilike 1,5 mm.
They will not dissolve, but swirling the juice in the glass will help re-suspend the granules if they sink. 
Granule se neće otopiti, no miješanjem soka u čaši, granule će se ponovno podići s dna čaše, ukoliko potonu.
Decreased prothrombine level, hepatocytolysis. 
Snižena razina protrombina, hepatocitoliza.
Smaller doses in children should be measured using the dosing spoon and given by sprinkling on apple sauce or yogurt. 
Manje doze u djece trebaju se izmjeriti žlicom za doziranje i dati posipane na kašicu od jabuke ili jogurt.
The concentration of the metabolite may be increased in cases of renal failure. 
Koncentracija metabolita može se povisiti u slučaju zatajenja bubrega.
Sodium aminosalicylic acid was not mutagenic in Ames test strain TA 100. 
Natrij aminosalicilatna kiselina nije bila mutagena u Ames testu soja TA 100.
If you are not sure, talk to your doctor or pharmacist before taking GRANUPAS. 
Ako niste sigurni obratite se svom liječniku ili ljekarniku prije uzimanja lijeka GRANUPAS.
In the event of overdose, it is recommended that the patient is monitored for any signs or symptoms of adverse reactions and that appropriate symptomatic treatment is instituted immediately. 
U slučaju predoziranja preporučuje se praćenje znakova i simptoma nuspojava u bolesnika i trenutno započinjanje simptomatskog liječenja.
Given that the metabolites of para-aminosalicylic acid are largely excreted via glomerular filtration, caution is warranted in patients with mild to moderate renal impairment (see also section 4.3). 
Budući da se metaboliti paraaminosalicilatne kiseline uvelike izlučuju putem glomerularne filtracije, lijek se treba primjenjivati oprezno u bolesnika s blagim do umjerenim oštećenjem bubrega (vidjeti također dio 4.3).
The sachets can be stored below 25°C up to 24 hours after first opening. 
Vrećice se mogu čuvati pri temperaturama do 25°C do 24 sata nakon prvog otvaranja.
Patients should be advised that the skeletons of the granules may be seen in the stools. 
Bolesnike treba upozoriti da se čestice granula mogu uočiti u stolici.
Frequency, type and severity of adverse reactions in children are expected to be the same as in adults. 
Očekuju se ista učestalost, tip i težina nuspojava u djece kao i u odraslih osoba.
• prolonged bleeding time, 
• produljeno vrijeme krvarenja,
Given the metabolic pathway of para-aminosalicylic acid no significant drug interaction is anticipated. 
Uzimajući u obzir metabolički put paraaminosalicilatne kiseline, ne očekuju se značajne interakcije lijeka.
Any granules left-over at the bottom of the glass should be swallowed immediately by adding a small quantity of liquid. 
Ako granule ostanu na dnu čaše, trebaju se odmah progutati s malom količinom tekućine.
The mechanism of action of para-aminosalicylic acid resembles the sulfonamides, competing with paraminobenzoic acid (PABA) for dihydropteroate synthetase (DHP), a key enzyme in the biosynthesis of folates. 
Mehanizam djelovanja paraaminosalicilatne kiseline sličan je sulfonamidima, koji se natječu s paraminobenzoinskom kiselinom (PABA) za sintetazu dihidropteroata (DHP), ključnog enzima u biosintezi folata.
In the rabbit, sodium aminosalicylate had no effects on embryofoetal development; however, the doses evaluated were below those proposed clinically. 
U kunića, natrijev aminosalicilat nije imao učinaka na embrio-fetalni razvoj, no ispitivane doze su bile manje od klinički predloženih.
(*) in subjects also infected with HIV thyroid gland problems and specifically underactive thyroid or low levels of thyroid hormones, are a very common side effect that may affect more than 1 in 10 people. 
(*) kod osoba koje su zaražene i HIV-om, problemi sa štitnom žlijezdom, a naročito smanjena aktivnost štitinjače ili niske vrijednosti hormona štitnjače, vrlo su česta nuspojava koja se može javiti u više od 1 na 10 osoba.
The sachets can be stored below 25°C up to 24 hours after opening. 
Vrećice se mogu čuvati pri temperaturi manjoj od 25°C do 24 sata nakon otvaranja.
GRANUPAS is a gastro-resistant preparation and, therefore, the acid-resistant coating of the granules protects against degradation in the stomach therefore preventing the formation of meta-aminophenol (a known hepatotoxin). 
GRANUPAS je želučanootporan pripravak i ovojnica granula otporna na kiselinu štiti granule od degradacije u želucu sprječavajući tako formiranje metaaminofenola (poznatog hepatotoksina).
GRANUPAS is not recommended during pregnancy and in women of childbearing potential not using contraception. 
Ne preporučuje se koristiti lijek GRANUPAS tijekom trudnoće niti u žena reproduktivne dobi koje ne koriste kontracepciju.
o Tap the spoon once on a table to give a horizontal level of granules and continue filling if necessary. 
o Kucnite žlicom jednom o stol kako bi se granule vodoravno poravnale te nadopunite prema potrebi.
In a single dose study the plasma half-life of para-aminosalicylic acid administered as GRANUPAS was 1.62 ± 0.85 h. 
U ispitivanju jedne doze, poluvijek u plazmi paraaminosalicilatne kiseline primijenjene kao GRANUPAS iznosio je 1,62±0,85 h.
The major metabolites of PAS are produced by conjugation to glycine in para-aminosalicyluric acid (PASU) for up to 25% of the dose and to N-acetyl in N-acetyl para-aminosalicylic acid (Ac-PAS) for up to 70% of the dose. 
Većina metabolita PAS-a nastaje konjugacijom do glicina u paraaminosaliciluričnoj kiselini (PASU) do 25% doze i do N-acetila u N-acetil paraaminosalicilatnoj kiselini (Ac-PAS) do 70% doze.
Para-aminosalicylic acid may cause hepatitis. 
Paraaminosalicilatna kiselina može uzrokovati hepatitis.
What you need to know before you take GRANUPAS Do not take GRANUPAS 
Što morate znati prije nego počnete uzimati GRANUPAS
Common Giddiness, vestibular syndrome. 
Omaglica, vestibularni sindrom
A malabsorption syndrome can develop in patients on para-aminosalicylic acid, but is usually not complete. 
Malapsorpcijski sindrom se može razviti u bolesnika liječenih paraaminosalicilatnom kiselinom, no ovaj sindrom najčešće nije potpuno razvijen.
Small amounts of this agent are distributed in the milk and bile. 
Male količine ovog lijeka distribuirane su u majčinom mlijeku i žuči.
Because the granules are protected by an enteric coating, absorption does not commence until they leave the stomach. 
Budući da su granule presvučene ovojnicom otpornom na želučanu kiselinu, apsorpcija granula ne započinje dok ne napuste želudac.
The contents of the sachet should be added to a glass of orange or tomato juice. 
Sadržaj vrećice treba dodati u čašu soka od naranče ili soka od rajčice.
Very rare Thrombocytopenia, purpura, leukopenia, anemia, methemoglobinemia, agranulocytosis. 
Trombocitopenija, purpura, leukopenija, anemija, methemoglobinemija, agranulocitoza
The granules should not be crushed or chewed, as this impairs the gastro-resistant coating. 
Granule se ne smiju zdrobiti ni žvakati jer to oštećuje želučanootporni film.
Increased blood alkaline phosphatase, transaminases, weight loss. 
Povišene vrijednosti alkalne fosfataze u krvi, Povišene vrijednosti transaminaza, gubitak težine
Do not chew or crush. 
Ne žvakati ili drobiti.
This medicine is presented as light brown gastro-resistant granules in sachets. 
Ovaj se lijek isporučuje kao svjetlosmeđe želučanootporne granule u vrećicama.
Methacrylic acid - Ethyl acrylate copolymer (1:1) Dispersion 30 per cent Hypromellose 
Metakrilatna kiselina - etilakrilat kopolimer (1:1), 30-postotna disperzija Hipromeloza
Para-aminosalicylic acid may decrease the gastrointestinal absorption of digoxin, by inhibiting the absorption function of intestinal cells. 
Paraaminosalicilatna kiselina može smanjiti gastrointestinalnu apsorpciju digoksina inhibirajući apsorpcijsku funkciju intestinalnih stanica.
An in vivo genotoxicity study (micronucleus test) has been conducted with para-aminosalicylic acid. 
Provedena je in vivo studija genotoksičnosti (test mikronuklusa) s paraaminosalicilatnom kiselinom.
The small granules are designed to escape the restriction on gastric emptying of large particles. 
Male su granule dizajnirane tako da izbjegnu ograničenje izlaska velikih čestica iz želuca.
info@lucanepharma.com 
info@lucanepharma.com info@lucanepharma.com
Para-aminosalicylic acid is distributed in various tissues and fluids including the lungs, kidneys, liver and peritoneal fluid. 
Paraaminosalicilatna kiselina distribuira se u različitim tkivima i tekućinama, uključujući pluća, bubrege, jetru i peritonealnu tekućinu.
EU/1/13/896/001 
12. BROJ(EVI) ODOBRENJA ZA STAVLJANJE LIJEKA U PROMET EU/1/13/896/001
Gastric ulcer 
Ulkus želuca
• if you have severe kidney disease. 
• ako bolujete od teške bolesti bubrega.
Hypothyroidism in HIV co-infected patients is a very common event and occurs in ≥ 1/10 subjects, particularly when para-aminosalicylic acid is administered with ethionamide/prothionamide. 
Hipotireoza u bolesnika istodobno zaraženih HIV-om je vrlo čest događaj i pojavljuje se u ≥1/10 osoba, posebno kada se paraaminosalicilatna kiselina primjenjuje s etionamidom/protionamidom.
GRANUPAS is indicated for use as part of an appropriate combination regimen for multi-drug resistant tuberculosis in adults and paediatric patients from 28 days of age and older when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability. 
GRANUPAS je indiciran za liječenje multirezistentne tuberkuloze kao dio odgovarajuće kombinirane terapijske sheme u odraslih i pedijatrijskih bolesnika u dobi od 28 dana i starijih kada se zbog rezistencije ili nepodnošljivosti lijeka ne mogu koristiti uobičajene kombinacije lijekova.
Malabsorption syndrome*, peptic ulcer, gastrointestinal bleeding, jaundice, metallic taste. 
Malapsorpcijski sindrom*, peptički ulkus, gastrointestinalno krvarenje, žutica, metalni okus
Literature reports on para- aminosalicylic acid in pregnant women always report co-administration of other medicinal products. 
Podaci dostupni u literaturi o primjeni paraaminosalicilatne kiseline u trudnica uvijek navode istovremenu primjenu drugih lijekova.
Malabsorption syndrome 
Sindrom malapsorpcije
The complete syndrome includes steatorrhoea, an abnormal small bowel pattern on x-ray, villus atrophy, depressed cholesterol, reduced D-xylose and iron absorption. 
Potpuni malapsorpcijski sindrom uključuje steatoreju, abnormalne nalaze tankog crijeva na rendgenskim snimkama, atrofiju crijevnih resica, snižene vrijednosti kolesterola, smanjenu apsorpciju D-ksiloze i željeza.