natgillin/translations-raw huggingface dataset:
Appendix A of the European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes (ETS No. 123)
Appendix A of the European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes (ETS No. 123)
Blakey, D.H., G.R.
Blakey, D.H., G.R.
Douglas (1984), Transient DNA lesions induced by benzo[a]pyrene in Chinese hamster ovary cells, Mutation Research, Vol. 140/2-3, pp. 141-45.
Douglas (1984), Transient DNA lesions induced by benzo[a]pyrene in Chinese hamster ovary cells, Mutation Research, Vol. 140/2-3, str. 141.–45.
Douglas (1990), The role of excision repair in the removal of transient benzo[a]pyrene-induced DNA lesions in Chinese hamster ovary cells, Mutation Research, Vol. 236/1, pp. 35-41.
Douglas (1990), The role of excision repair in the removal of transient benzo[a]pyrene-induced DNA lesions in Chinese hamster ovary cells, Mutation Research, Vol. 236/1, str. 35.–41.
Nakajima, M. (2012), Tissue sample preparation for in vivo rodent alkaline Comet assay, Genes and Environment, Vol. 34/1, pp. 50-4.
Nakajima, M. (2012), Tissue sample preparation for in vivo rodent alkaline Comet assay, Genes and Environment, Vol. 34/1, str. 50.–4.
Atlas of Comet Assay Images, Scientist Press Co., Ltd., Tokyo, Japan.
Atlas of Comet Assay Images, Scientist Press Co., Ltd., Tokyo, Japan.
Lovell, D.P., G. Thomas, R. Dubow (1999), Issues related to the experimental design and subsequent statistical analysis of in vivo and in vitro Comet studies, Teratogenesis Carcinogenesis Mutagenesis, Vol. 19/2, pp. 109-19.
Lovell, D.P., G. Thomas, R. Dubow (1999), Issues related to the experimental design and subsequent statistical analysis of in vivo and in vitro Comet studies, Teratogenesis Carcinogenesis Mutagenesis, Vol. 19/2, str. 109.–19.
Wiklund, S.J., E. Agurell (2003), Aspects of design and statistical analysis in the Comet assay, Mutagenesis, Vol. 18/2, pp. 167-75.
Wiklund, S.J., E. Agurell (2003), Aspects of design and statistical analysis in the Comet assay, Mutagenesis, Vol. 18/2, str. 167.–75.
Lovell, D.P., T. Omori (2008), Statistical issues in the use of the Comet assay, Mutagenesis, Vol. 23/3, pp. 171-82.
Lovell, D.P., T. Omori (2008), Statistical issues in the use of the Comet assay, Mutagenesis, Vol. 23/3, str. 171.–82.
Box, G.E.P, Hunter, W.G. and Hunter, J.S.
Box, G.E.P, Hunter, W.G. and Hunter, J.S.
Box G.E.P.
Box G.E.P.
Doncaster, C.P.
Doncaster, C.P.
Mead, R. (1990) The Design of Experiments.
Mead, R. (1990) The Design of Experiments.
Montgomery D.C.
Montgomery D.C.
Winer, B.J.
Winer, B.J.
Wu, C.F.J & Hamada, M.S.
Wu, C.F.J & Hamada, M.S.
Guerard, M., C. Marchand, U. Plappert-Helbig (2014), Influence of Experimental Conditions on Data Variability in the Liver Comet Assay, Environmental and Molecular Mutagenesis, Vol. 55/2, pp. 114-21.
Guerard, M., C. Marchand, U. Plappert-Helbig (2014), Influence of Experimental Conditions on Data Variability in the Liver Comet Assay, Environmental and Molecular Mutagenesis, Vol. 55/2, str. 114.–21.
Recio L, Hobbs C, Caspary W, Witt KL, (2010), Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol, J. Toxicol.
Recio L, Hobbs C, Caspary W, Witt KL, (2010), Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol, J. Toxicol.
Early in 2004 a draft protocol (38), designed to measure the bioaccumulation potential of poorly water soluble organic substances for which the standard water exposure bioconcentration method was not practicable, together with a supporting background document (39), was submitted to an EU PBT working group.
Početkom 2004. radnoj skupini EU-a za tvari s postojanim, bioakumulativnim i otrovnim svojstvima dostavljen je nacrt protokola (38.) osmišljenog za mjerenje potencijala bioakumulacije organskih tvari koje su slabo topljive u vodi i za koje nije moguće provesti standardnu metodu ispitivanja biokoncentracije vodenim izlaganjem, zajedno s popratnim dokumentom (39.).
Further justification given for the method was that potential environmental exposure to such poorly soluble substances (i.e. log KOW >5) may be largely via the diet (cf. (40) (41) (42) (43) (44)).
Dodatno je pojašnjenje za tu metodu bilo da do potencijalne izloženosti okoliša takvim tvarima slabe topljivosti (odnosno čija je vrijednost log KOW > 5) uglavnom može doći kroz hranu (vidjeti 40., 41., 42., 43., 44.).
For this reason, dietary exposure tests are referred to in some published chemicals regulations [43].
Stoga se na ispitivanja izlaganjem kroz hranu upućuje u određenim objavljenim uredbama o kemikalijama [43].
It should be realised however, that in the method described here exposure via the aqueous phase is carefully avoided and thus a BMF value from this test method cannot directly be compared to a BMF value from a field study (in which both water and dietary exposure may be combined).
Međutim, potrebno je naglasiti da se u metodi koja se ovdje opisuje pažljivo izbjegava izlaganje kroz vodenu fazu te se stoga vrijednost BMF-a iz ove ispitne metode ne može izravno usporediti s vrijednošću BMF-a iz terenskih ispitivanja (u kojima je moguće kombinirati vodeno izlaganje i izlaganje kroz hranu).
This section of the present test method is based on this protocol (38) and is a new method that did not appear in the previous version of TM C.13.
Ovaj se odjeljak trenutačne ispitne metode temelji na protokolu (38.) te je riječ o novoj metodi koja nije objavljena u prethodnoj verziji ispitne metode C.13.
This alternative test allows the dietary exposure pathway to be directly investigated under controlled laboratory conditions.
Ovim se alternativnim ispitivanjem omogućuje izravno istraživanje puta izlaganja kroz hranu u kontroliranim laboratorijskim uvjetima.
Li A, Doucette W.J.
Li A, Doucette W.J.
Environ Toxicol Chem 12: 2031-2035
Environ Toxicol Chem 12: 2031-2035.
(OECD (1997), OECD Environmental Health and Safety Publications Series on Testing and Assessment Number 7: Guidance Document on Direct Phototransformation of Chemicals in Water OCDE/GD(97)21. Organisation for Economic Co-operation and Development (OECD), Paris, France.
(OECD (1997), OECD Environmental Health and Safety Publications Series on Testing and Assessment Number 7: Guidance Document on Direct Phototransformation of Chemicals in Water OCDE/GD(97)21. Organisation for Economic Co-operation and Development (OECD), Paris, France.
OECD (2011), QSAR Toolbox 2.1.
OECD (2011), QSAR Toolbox 2.1.
Brown R.S., Akhtar P., Åkerman J., Hampel L., Kozin I.S., Villerius L.A. and Klamer H.J.C.
Brown R.S., Akhtar P., Åkerman J., Hampel L., Kozin I.S., Villerius L.A. and Klamer H.J.C.
Fernandez J.D., Denny J.S. and Tietge J.E.
Fernandez J.D., Denny J.S. and Tietge J.E.
Nichols J.W., Fitzsimmons P.N., Whiteman F.W. and Dawson T.D.
Nichols J.W., Fitzsimmons P.N., Whiteman F.W. and Dawson T.D.
Parkerton T.F., Arnot J.A., Weisbrod A.V., Russom C., Hoke R.A., Woodburn K., Traas T., Bonnell M., Burkhard L.P. and Lampi M.A.
Parkerton T.F., Arnot J.A., Weisbrod A.V., Russom C., Hoke R.A., Woodburn K., Traas T., Bonnell M., Burkhard L.P. and Lampi M.A.
Verbruggen E.M.J., Beek M., Pijnenburg J. and Traas T.P.
Verbruggen E.M.J., Beek M., Pijnenburg J. and Traas T.P.
Schlechtriem C., Fliedner A. and Schäfers C. (2012), Determination of lipid content in fish samples from bioaccumulation studies: Contributions to the revision of OECD Test Guideline 305.
Schlechtriem C., Fliedner A. and Schäfers C. (2012), Determination of lipid content in fish samples from bioaccumulation studies: Contributions to the revision of OECD Test Guideline 305.
OECD (2000), OECD Environmental Health and Safety Publications Series on Testing and Assessment No. 23: Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures ENV/JM/MONO(2000)6.
OECD (2000), OECD Environmental Health and Safety Publications Series on Testing and Assessment No. 23: Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures ENV/JM/MONO(2000)6.
US-EPA (1994), Great Lake water quality initiative technical support document for the procedure to determine bioaccumulation factors 822-R-94-002.
US-EPA (1994), Great Lake water quality initiative technical support document for the procedure to determine bioaccumulation factors 822-R-94-002.
US-FDA (1999), Pesticide analytical manual (PAM).
US-FDA (1999), Pesticide analytical manual (PAM).
US-EPA (1974), Section 5, A (1) Analysis of Human or Animal Adipose Tissue, in Analysis of Pesticide Residues in Human and Environmental Samples, Thompson, J.F., Editor.
US-EPA (1974), Section 5, A (1) Analysis of Human or Animal Adipose Tissue, in Analysis of Pesticide Residues in Human and Environmental Samples, Thompson, J.F., Editor.
Bligh E.G. and Dyer W.J.
Bligh E.G. and Dyer W.J.
Gardner W.S., Frez W.A., Cichocki E.A. and Parrish C.C.
Gardner W.S., Frez W.A., Cichocki E.A. and Parrish C.C.
Smedes F. (1999), Determination of total lipid using non-chlorinated solvents.
Smedes F. (1999), Determination of total lipid using non-chlorinated solvents.
OECD (2006), OECD Environmental Health and Safety Publications Series on Testing and Assessment No. 54: Current approaches in the statistical analysis of ecotoxicity data: a guidance to application.
OECD (2006), OECD Environmental Health and Safety Publications Series on Testing and Assessment No. 54: Current approaches in the statistical analysis of ecotoxicity data: a guidance to application.
Springer T.A., Guiney P.D., Krueger H.O. and Jaber M.J.
Springer T.A., Guiney P.D., Krueger H.O. and Jaber M.J.
Springer T.A.
Springer T.A.
Arnot J.A., Meylan W., Tunkel J., Howard P.H., Mackay D., Bonnell M. and Boethling R.S.
Arnot J.A., Meylan W., Tunkel J., Howard P.H., Mackay D., Bonnell M. and Boethling R.S.
Parkerton T., Letinski D., Febbo E., Davi R., Dzambia C., Connelly M., Christensen K. and Peterson D. (2001), A practical testing approach for assessing bioaccumulation potential of poorly water soluble organic chemicals (presentation). in SETAC Europe 12th Annual Meeting: Madrid, Spain.
Parkerton T., Letinski D., Febbo E., Davi R., Dzambia C., Connelly M., Christensen K. and Peterson D. (2001), A practical testing approach for assessing bioaccumulation potential of poorly water soluble organic chemicals (presentation). in SETAC Europe 12th Annual Meeting: Madrid, Spain.
Fisk A.T., Cymbalisty C.D., Bergman Ã. and Muir D.C.G.
Fisk A.T., Cymbalisty C.D., Bergman Ã. and Muir D.C.G.
Anonymous (2004), Fish, dietary bioaccumulation study — Basic protocol, document submitted to the TC-NES WG on PBT.
Anonymous (2004), Fish, dietary bioaccumulation study – Basic protocol, document submitted to the TC-NES WG on PBT.
Anonymous (2004), Background document to the fish dietary study protocol, document submitted to the TC-NES WG on PBT.
Anonymous (2004), Background document to the fish dietary study protocol, document submitted to the TC-NES WG on PBT.
Bruggeman W.A., Opperhuizen A., Wijbenga A. and Hutzinger O. (1984), Bioaccumulation of super-lipophilic chemicals in fish, Toxicol.
Bruggeman W.A., Opperhuizen A., Wijbenga A. and Hutzinger O. (1984), Bioaccumulation of super-lipophilic chemicals in fish, Toxicol.
Muir D.C.G., Marshall W.K. and Webster G.R.B.
Muir D.C.G., Marshall W.K. and Webster G.R.B.
Thomann R.V.
Thomann R.V.
Nichols J.W., Fitzsimmons P.N. and Whiteman F.W.
Nichols J.W., Fitzsimmons P.N. and Whiteman F.W.
Gobas F.A.P.C., de Wolf W., Burkhard L.P., Verbruggen E. and Plotzke K. (2009), Revisiting bioaccumulation criteria for POPs and PBT assessments.
Gobas F.A.P.C., de Wolf W., Burkhard L.P., Verbruggen E. and Plotzke K. (2009), Revisiting bioaccumulation criteria for POPs and PBT assessments.
5: 624-637.
5: 624. – 637
Fisk A.T., Norstrom R.J., Cymbalisty C.D. and Muir D.G.G.
Fisk A.T., Norstrom R.J., Cymbalisty C.D. and Muir D.G.G.
McGrath J.A., Parkerton T.F. and Di Toro D.M.
McGrath J.A., Parkerton T.F. and Di Toro D.M.
Poppendieck D.G.
Poppendieck D.G.
McCarty L.S. and Mackay D. (1993), Enhancing ecotoxicological modelling and assessment: body residues and modes of toxic action.
McCarty L.S. and Mackay D. (1993), Enhancing ecotoxicological modelling and assessment: body residues and modes of toxic action.
Part II — Additional Report including comparative analysis of trout and carp results ENV/JM/MONO(2012)20.
Part II – Additional Report including comparative analysis of trout and carp results ENV/JM/MONO(2012)20.
20 – 25
20 – 25
13 – 17
13 – 17
Meyer A., Biermann C.H. and Orti G. (1993), The phylogenetic position of the zebrafish (Danio rerio), a model system in developmental biology: An invitation to the comparative method Proc.
Meyer A., Biermann C.H. and Orti G. (1993), The phylogenetic position of the zebrafish (Danio rerio), a model system in developmental biology: An invitation to the comparative method Proc.
SAMPLING SCHEDULES FOR AQUEOUS AND DIETARY EXPOSURE TESTS
RASPOREDI UZORKOVANJA ZA ISPITIVANJA VODENIM IZLAGANJEM I IZLAGANJEM KROZ HRANU
Fish Sampling
Uzorkovanje riba
No. of fish per sample [1]
Br. riba po uzorku [1]
Minimal required frequency (days) [2]
Minimalna učestalost (dani) [2]
Additional sampling (days) [2]
Dodatno uzorkovanje (dani) [2]
Transfer fish to water free of test substance
Prenijeti ribe u vodu bez ispitivane tvari
However, sections 5, 6 and 8 are only relevant for the aqueous exposure method but are included here as they are “general” techniques.
Međutim, odjeljci 5., 6. i 8. relevantni su jedino za metodu izlaganja kroz hranu, ali ovdje su uključeni jer se odnose na ‚opće’ tehnike.
The sequential (sections 4 and 5) and simultaneous (section 6) methods allow the calculation of uptake and depuration constants which are used to derive kinetic BCFs.
Sekvencijske metode (odjeljci 4. i 5.) i simultane metode (odjeljak 6.) omogućuju izračunavanje konstanti apsorpcije i izlučivanja koje se upotrebljavaju za dobivanje kinetičkih BCF-ova.
[Equation A5.17]
[jednadžba A5.17]
For example, the duration of the uptake phase (i.e. time to reach a certain percentage of steady-state, e.g. t80 or t95) for a test substance with log KOW = 4 would be (using Equation A5.5, Equation A5.16 and Equation A5.17):
Primjerice, trajanje faze apsorpcije (tj. vrijeme potrebno da se postigne određeni postotak stabilnog stanja, npr. t80 ili t95) za ispitivanu tvar čiji je log KOW = 4 bilo bi (primjenom jednadžbe A5.5, jednadžbe A5.16 i jednadžbe A5.17):
2,45days59 hours
2,45dana59 sati
4,60days110 hours
4,60dana110 sati
teSS = 6,54 · 10 – 3 · KOW + 55,31 (hours)
teSS = 6,54 · 10 – 3 · KOW + 55,31 (sati)
[Equation A5.19]
[jednadžba A5.19]
When k1/k2 is substituted by BCF (cf. Equation A5.4) in Equation A5.25 and Equation A5.26, the standard error and 95 % CI of the BCF can be estimated as well.
Ako se u jednadžbi A5.25 i jednadžbi A5.26 vrijednost k1/k2 zamijeni vrijednošću BCF (vidjeti jednadžbu A5.4), mogu se procijeniti standardna pogreška i interval 95 %-tne pouzdanosti za BCF. To je posebno korisno kada se uspoređuju različite procjene koje su posljedica transformacije podataka.
This is especially useful when comparing different estimates due to data transformation.
Zavisna varijabla (koncentracija u ribi) može se prilagoditi s ln-transformacijom ili bez nje te se može ocijeniti dobivena nesigurnost u pogledu BCF-a.
The dependent variable (fish concentration) can be fitted with or without ln transformation, and the resulting BCF uncertainty can be evaluated.
Budući da postoji snažna korelacija između parametara k1 i k2 ako se procjenjuju istodobno, možda je bolje prvo izračunati k2 samo iz podataka o izlučivanju (vidjeti prethodno navedeno); k2 se u većini slučajeva može prilično precizno procijeniti iz krivulje izlučivanja.
As a strong correlation exists between the two parameters k1 and k2 if estimated simultaneously, it may be advisable first to calculate k2 from the depuration data only (see above); k2 in most cases can be estimated from the depuration curve with relatively high precision. k1 can be subsequently calculated from the uptake data using non-linear regression [6].
Potom se k1 može izračunati iz podataka o apsorpciji s pomoću nelinearne regresije [6]. Savjetuje se da se pri sekvencijskom prilagođavanju podaci transformiraju na isti način.
One of the most common complications is fish growth during the test.
Jedna od najčešćih komplikacija rast je riba tijekom ispitivanja.
GROWTH DILUTION CORRECTION FOR KINETIC BCF AND BMF
ISPRAVLJANJE U ODNOSU NA RAZRJEĐENJE ZBOG RASTA ZA KINETIČKI BCF I BMF
In case there are indications that first order kinetics do not apply, it is advised to seek advice from a biostatistician for a proper correction of growth dilution or to use the mass based approach described below.
U slučajevima u kojima postoje pokazatelji da kinetika prvog reda ne vrijedi, preporučuje se potražiti savjet biostatističara o prikladnom ispravljanju u odnosu na razrjeđenje zbog rasta ili primijeniti pristup koji se temelji na masi, koji je opisan u nastavku.
In some cases this method for correcting growth dilution is subject to a lack of precision or sometimes does not work (for example for very slowly depurating substances tested in fast growing fish the derived depuration rate constant corrected for growth dilution, k2g, may be very small and so the error in the two rate constants used to derive it become critical, and in some cases kg estimates may be larger than k2).
U nekim slučajevima metodi ispravljanja u odnosu na razrjeđenje zbog rasta nedostaje preciznosti ili ponekad ne djeluje (na primjer kod tvari koje se izlučuju vrlo polako i ispituju u ribama koje brzo rastu izvedena konstanta brzine izlučivanja ispravljena u odnosu na razrjeđenje zbog rasta k2g može biti vrlo mala pa pogreška u dvjema konstantama brzina upotrijebljenima za dobivanje te vrijednosti postaje kritična te u nekim slučajevima procijenjena vrijednost kg može biti viša od vrijednosti k2).
In such cases an alternative approach (i.e. mass approach), which also works when first order growth kinetics have not been obeyed, can be used which avoids the need for the correction.
U takvim se slučajevima može primijeniti alternativni pristup (tj. pristup na temelju podataka o masi), kojim se izbjegava potreba za ispravljanjem i koji djeluje čak i kada nema kinetike prvog reda.
This approach is outlined at the end of this section.
Taj je pristup prikazan na kraju ovog odjeljka.
Growth rate constant subtraction method for growth correction
Ispravljanje u odnosu na rast metodom oduzimanja konstante brzine rasta
For the standard method all individual weight and length data are converted to natural logarithms and ln(weight) or ln(1/weight) is plotted vs. time (day), separately for treatment and control groups.
Kod standardne metode sve se pojedinačne mase i dužine preračunavaju u prirodne logaritme te se ln(masa) ili ln(1/masa) grafički prikazuje u odnosu na vrijeme (dan), odvojeno za ispitne i kontrolne skupine.
Generally for growth dilution correction it is more appropriate to use the weight data from the whole study to derive the growth rate constant (kg), but statistically significant differences between the growth rate constants derived for the uptake phase and depuration phase may indicate that the depuration phase rate constant should be used.
Općenito, za ispravljanje u odnosu na razrjeđenje zbog rasta primjerenije je upotrijebiti podatke o masi iz cijelog ispitivanja da bi se dobila konstanta brzine rasta (kg), ali statistički značajne razlike između konstanti brzine rasta dobivenih za fazu apsorpcije i fazu izlučivanja mogu upućivati na to da bi trebalo upotrijebiti konstantu brzine dobivenu za fazu izlučivanja.
Overall growth rates from aqueous studies for test and control groups can be used to check for any treatment related effects.
Ukupne brzine rasta koje su za ispitne i kontrolne skupine utvrđene ispitivanjima u kojima je primijenjeno vodeno izlaganje mogu se upotrijebiti za provjeru učinaka povezanih s tretiranjem.
The variances in the slopes of the lines are calculated and used to evaluate the statistical significance (p = 0,05) of the difference in the slopes (growth rate constants) using the student t-test (or ANOVA if more than one concentration is tested).
Izračunavaju se varijance u nagibu pravaca te se upotrebljavaju za procjenu statističke značajnosti (p = 0,05) razlike u nagibima (konstantama brzine rasta) primjenom Studentova t-testa (ili ANOVA-e ako se ispituje više od jedne koncentracije).
Weight data are generally preferred for growth correction purposes.
Za potrebe ispravljanja u odnosu na rast uglavnom je poželjnije upotrebljavati podatke o masi.
Length data, treated in the same way, may be useful to compare control and test groups for treatment related effects.
Podaci o duljini, s kojima se postupa na isti način, mogu biti korisni za uspoređivanje kontrolnih i ispitnih skupina u pogledu učinaka povezanih s tretiranjem.
If there is no statistically significant difference in the weight data analysis, the test and control data may be pooled and an overall fish growth rate constant for the study (kg) calculated as the overall slope of the linear correlation.
Ako se analizom podataka o masi ne utvrdi statistički značajna razlika, podaci dobiveni za ispitne i kontrolne skupine mogu se objediniti te se može izračunati ukupna konstanta brzine rasta riba u ispitivanju (kg) kao ukupan nagib linearne korelacije.
If statistically significant differences are observed, growth rate constants for each fish group, and/or study phase, are reported separately.
Ako se opaze statistički značajne razlike, konstante brzine rasta navode se odvojeno za svaku skupinu riba i/ili fazu ispitivanja.
The rate constant from each treated group should then be used for growth dilution correction purposes of that group.
Konstantu brzine utvrđenu za pojedinu tretiranu skupinu trebalo bi potom upotrijebiti za potrebe ispravljanja u odnosu na razrjeđenje zbog rasta za tu skupinu.
If statistical differences between the uptake and depuration phase rate constants were noted, depuration phase derived rate constants should be used.
Ako su zabilježene statistički značajne razlike između konstanti brzine apsorpcije i izlučivanja, trebalo bi upotrijebiti konstante brzine dobivene u fazi izlučivanja.
The calculated growth rate constant (kg expressed as day-1) can be subtracted from the overall depuration rate constant (k2) to give the depuration rate constant, k2g.
Izračunana konstanta brzine rasta (kg iskazan kao dan– 1) može se oduzeti od ukupne konstante brzine izlučivanja (k2) kako bi se dobila konstanta brzine izlučivanja k2g.
[Equation A5.27]
[jednadžba A5.27]
The uptake rate constant is divided by the growth-corrected depuration rate constant to give the growth-corrected kinetic BCF, denoted BCFKg (or BMFKg).
Konstanta brzine apsorpcije dijeli se s konstantom brzine izlučivanja ispravljenom u odnosu na rast kako bi se dobio kinetički BCF ispravljen u odnosu na rast, koji se označuje kao BCFKg (ili BMFKg).
[Equation A5.28]
[jednadžba A5.28]
The growth rate constant derived for a dietary study is used in Equation A7.5 to calculate the growth corrected BMFKg (cf. Appendix 7).
Konstanta brzine rasta dobivena za ispitivanje u kojemu je primijenjeno izlaganje kroz hranu upotrebljava se u jednadžbi A7.5 kako bi se izračunao BMFKg ispravljen u odnosu na rast (vidjeti Dodatak 7.).
Mass based method for growth correction
Ispravljanje u odnosu na rast metodom koja se temelji na podacima o masi
An alternative to the above “growth rate constant subtraction method” that avoids the need to correct for growth can be used as follows.
Umjesto prethodno opisane ‚metode oduzimanja konstante brzine rasta’ može se upotrijebiti i sljedeća metoda kako bi se izbjegla potreba za ispravljanjem u odnosu na rast.
The principle is to use depuration data on a mass basis per whole fish rather than on a concentration basis.
Temelji se na načelu upotrebe podataka o izlučivanju na osnovi mase po cijeloj ribi, a ne na osnovi koncentracije.