natgillin/translations-raw huggingface dataset:
Symptoms include acute onset of decreased visual acuity or ocular pain and typically occur within hours to weeks of telmisartan hydrochlorothiazide initiation.
Simptomi uključuju akutan nastup smanjene oštrine vida ili boli u očima, a karakteristično je da se pojavljuju unutar nekoliko sati do tjedana od početka primjene telmisartan hidroklorotiazida.
<1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data).
<1/10); manje često (≥1/1000 i <1/100); rijetko (≥1/10 000 i <1/1000); vrlo rijetko (<1/10 000); nepoznato (ne može se procijeniti iz dostupnih podataka).
Actelsar HCT should not be given to patients with cholestasis, biliary obstructive disorders or severe hepatic insufficiency (see section 4.3) since telmisartan is mostly eliminated with the bile.
Actelsar HCT ne smije se davati bolesnicima s kolestazom, bilijarnim opstruktivnim poremećajima ili teškom insuficijencijom jetre (vidjeti dio 4.3), s obzirom da se telmisartan uglavnom eliminira putem žuči.
One study included a population comprised of 71,533 cases of BCC and of 8,629 cases of SCC matched to 1,430,833 and 172,462 population controls, respectively.
71 533 slučaja BCC-a i 8629 slučajeva SCC-a usklađenih s 1 430 833, odnosno 172 462 kontrola u populaciji.
As with all other angiotensin II receptor antagonists, telmisartan is apparently less effective in lowering blood pressure in black patients than in non blacks, possibly because of higher prevalence of low renin states in the black hypertensive population.
Etničke razlike Kao i kod svih drugih antagonista receptora angiotenzina II, telmisartan je očigledno manje učinkoviti kod snižavanja krvnog tlaka kod ljudi crne rase nego kod ljudi koji nisu crne rase, vjerojatno zbog veće prevalencije niskih razina renina kod populacije crne rase s hipertenzijom.
- Hydrochlorothiazide belongs to a group of medicines called thiazide diuretics, which cause your urine output to increase, leading to a lowering of your blood pressure.
- Hidroklorotiazid pripada skupini lijekova koji se nazivaju tiazidski diuretici, koji uzrokuju povećano izlučivanje urina, što također snižava krvni tlak.
The use of Actelsar HCT in children and adolescents up to the age of 18 years is not recommended.
Primjena Actelsara HCT kod djece i adolescenata ispod 18 godina starosti se ne preporučuje.
If calcium supplements or calcium sparing medicinal products (e.g. vitamin D therapy) must be prescribed, serum calcium levels should be monitored and calcium dose adjusted accordingly.
Ako se moraju propisati nadomjesci kalcija ili lijekovi koji štede kalcij (npr. terapija vitaminom D), mora se pratiti serumske vrijednosti kalcija te u skladu s time prilagođavati dozu kalcija.
Increased incidence of sepsis has been observed with telmisartan only, however it can not be ruled out for Actelsar HCT.
Povećana učestalost sepse je primijećena samo uz telmisartan, ali se to ne može isključiti za Actelsar HCT.
No additional preclinical studies have been performed with the Fixed Dose Combination product 80 mg/25 mg.
Nisu provedene dodatne pretkliničke studije lijekova s kombinacijom fiksnih doza 80 mg/25 mg.
Hydrochlorothiazide: Following oral administration of telmisartan/hydrochlorothiazide, peak concentrations of hydrochlorothiazide are reached in approximately 1.0-3.0 hours after dosing.
Hidroklorotiazid: Nakon peroralne primjene telmisartana/hidroklorotiazida, vršne koncetracije hidroklorotiazida postižu se za oko 1,0-3,0 sati nakon doziranja.
Contains desiccant, do not eat.
Sadrži sredstvo za sušenje koje se ne smije pojesti.
- if you have severe liver problems such as cholestasis or biliary obstruction (problems with drainage of the bile from the liver and gall bladder) or any other severe liver disease.
- ako imate teške jetrene tegobe kao što je kolestaza ili opstrukcija žuči (poteškoće s istjecanjem žuči iz jetre i žučnog mjehura) ili neku drugu tešku bolest jetre.
Although clinically significant hyperkalaemia has not been documented with Actelsar HCT, risk factors for the development of hyperkalaemia include renal insufficiency and/or heart failure, and diabetes mellitus.
Iako klinički značajna hiperkalemija nije zabilježena uz Actelsar HCT, rizični faktori za razvoj hiperkalemije uključuju renalnu insuficijenciju i/ili zatajenje srca, te šećerna bolest.
Most cases of hepatic function abnormal/liver disorder from post-marketing experience with telmisartan occurred in Japanese patients.
Većina slučajeva abnormalne jetrene funkcije / poremećaja jetre iz iskustva u razdoblju nakon stavljanja telmisartana u promet pojavila se među japanskom populacijom.
The use of hydrochlorothiazide during breast feeding is not recommended.
Primjena hidroklorotiazida tijekom dojenja se ne preporučuje.
Actelsar HCT should be taken in patients whose blood pressure is not adequately controlled by telmisartan alone.
Actelsar HCT namijenjen je bolesnicima čiji se krvni tlak ne može adekvatno kontrolirati samo telmisartanom.
Therefore, it is not expected to potentiate bradykinin-mediated adverse events.
Stoga se ne očekuje potenciranje nuspojava posredovanih bradikininom.
Adverse reactions known to occur with each component given singly but which have not been seen in clinical trials may occur during treatment with Actelsar HCT.
Nuspojave za koje se zna da se pojavljuju sa svakom komponentom zasebno, ali nisu bile primijećene u kliničkim ispitivanjima mogu se pojaviti tijekom liječenja
Experience with telmisartan/hydrochlorothiazide is modest in the patients with mild to moderate renal impairment, therefore periodic monitoring of potassium, creatinine and uric acid serum levels is recommended.
Iskustvo s telmisartanom/hidroklorotiazidom je skromno kod bolesnika s blagim do umjerenim oštećenjem funkcije bubrega, stoga se preporučuje periodično praćenje serumskih vrijednosti kalija, kreatinina i mokraćne kiseline.
The other ingredients are magnesium stearate (E470b), potassium hydroxide, meglumine, povidone, sodium starch glycolate (type A), microcrystalline cellulose, mannitol (E421).
Drugi sastojci su magnezijev stearat (E470b), kalijev hidroksid, meglumin, povidon, natrijev škroboglikolat (vrste A), mikrokristalična celuloza, manitol (E421).
Thiazides may increase the risk of adverse events caused by amantadine.
Tiazidi mogu povećati rizik od nuspojava koje uzrokuje amantadin.
- Digoxin.
.- digoksin.
Al/Al blister, Al/PVC/PVDC blister and HDPE tablet container with LDPE cap and HDPE desiccant with silica filling.
Al/Al blister, Al/PVC/PVDC blister i HDPE spremnik za tablete sa LDPE zatvaračem i sredstvom za sušenje od silicijevog dioksida u HDPE spremniku.
1 Based on post-marketing experience 2 For further description, please see sub-section “Description of selected adverse reactions”
1 Na osnovi iskustva u razdoblju nakon stavljanja lijeka u promet 2 Za dodatni opis, molimo pogledajte odlomak „Opis izabranih nuspojava“
Therefore, the use of Actelsar HCT is not recommended.
Stoga se ne preporučuje primjena Actelsara HCT.
PARTICULARS TO APPEAR ON THE OUTER PACKAGING Carton for Al/PVC/PVDC blister
PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU Kutija za Al/PVC/PVDC blister
Medicinal products used in the treatment for gout (e.g. probenecid, sulfinpyrazone and allopurinol) Dose adjustment of uricosuric medicinal products may be necessary as hydrochlorothiazide may raise the level of serum uric acid.
Lijekovi koji se primjenjuju u liječenju gihta (npr. probenecid, sulfinpirazon i alopurinol) Može biti potrebna prilagodba doze urikozuričnih lijekova s obzirom da hidroklorotiazid može povisiti razinu mokraćne kiseline u serumu.
Telmisartan blocks the effect of angiotensin II so that the blood vessels relax, and your blood pressure is lowered.
Telmisartan blokira učinak angiotenzina II i tako opušta krvne žile te je krvni tlak niži.
Lupus-like syndrome, photosensitivity reactions, skin vasculitis, toxic epidermal necrolysis, erythema multiforme
Sindrom nalik na lupus, reakcije fotoosjetljivosti, vaskulitis kože, toksična epidermalna nekroliza, multiformni eritem
Anorexia, appetite decreased, electrolyte imbalance, hypercholesterolaemia, hyperglycaemia, hypovolaemia
Anoreksija, smanjeni apetit, neravnoteža elektrolita, hiperkolesterolemija, hiperglikemija, hipovolemija
Non-steroidal anti-inflammatory medicinal products (NSAIDs) NSAIDs (i.e. acetylsalicylic acid at anti-inflammatory dose regimens, COX-2 inhibitors and non-selective NSAIDs) may reduce the diuretic, natriuretic and antihypertensive effects of thiazide diuretics and the antihypertensive effects of angiotensin II receptor antagonists.
NSAIL-i (tj. acetilsalicilatna kiselina u protuupalnim režimima doziranja, COX-2 inhibitori i neselektivni NSAIL-i) mogu reducirati diuretski, natriuretski i antihipertenzivni učinak tiazidskih diuretika te antihipertenzivni učinak antagonista receptora angiotenzina II.
Actelsar HCT is used to treat high blood pressure (essential hypertension) in adults whose blood pressure is not controlled enough when telmisartan is used alone.
Actelsar HCT se primjenjuje u liječenju visokog krvnog tlaka (esencijalna hipertenzija) kod odraslih osoba čiji krvni tlak nije dobro kontroliran uz primjenu samog telmisartana.
Adverse reactions previously reported with one of the individual components may be potential adverse reactions with Actelsar HCT, even if not observed in clinical trials with this product.
Nuspojave prethodno prijavljene s jednom od individualnih komponenti mogu biti potencijalne nuspojave Actelsara HCT, čak iako nisu zabilježene u kliničkim ispitivanjima ovoga lijeka.
What you need to know before you take Actelsar HCT Do not take Actelsar HCT
Što morate znati prije nego počnete uzimati Actelsar HCT
Other medicines and Actelsar HCT
Drugi lijekovi i Actelsar HCT
Because no information is available regarding the use of telmisartan during breast-feeding, Actelsar HCT is not recommended and alternative treatments with better established safety profiles during breast-feeding are preferable, especially while nursing a newborn or preterm infant.
S obzirom da ne postoje raspoloživi podaci u vezi primjene Actelsara HCT tijekom dojenja, Actelsar HCT se ne preporučuje, te se preferiraju zamjenski lijekovi s utemeljenijim profilima sigurnosti tijekom dojenja, osobito u slučaju novorođenčeta ili prijevremeno rođenog djeteta.
If you forget to take Actelsar HCT
Ako ste zaboravili uzeti Actelsar HCT
Gastric lesions could be prevented/ameliorated by oral sodium chloride solution supplementation and group housing of animals.
Gastrične lezije mogu se spriječiti/ublažiti oralnim nadomjescima otopine natrijevog klorida i grupnim smještanjem životinja.
The effect of Actelsar HCT may be reduced when you take NSAIDs (non steroidal anti-inflammatory medicines, e.g. acetylsalicyl acid or ibuprofen).
Učinak Actelsara HCTse može smanjiti dok uzimate NSAIL-e (nesteroidni protuupalni lijekovi, npr. acetilsalicilatnu kiselinu ili ibuprofen).
Telmisartan: Following oral administration, peak concentrations of telmisartan are reached in 0.5-1.5 h after dosing.
Telmisartan: nakon peroralne primjene vršne koncetracije telmisartana postižu se 0,5-1,5 h nakon doziranja.
Sepsis including fatal outcome3 Blood and lymphatic system disorders Uncommon:
Sepsa uključujući fatalni ishod3 Poremećaji krvi i limfnog sustava Manje često:
3 For further description, please see sub-section “Description of selected adverse reactions”.
3 Za dodatni opis, molimo pogledajte odlomak „Opis izabranih nuspojava“
Possible side effects of Actelsar HCT:
Moguće nuspojave Actelsara HCT:
Actelsar HCT is a combination of an angiotensin II receptor antagonist, telmisartan, and a thiazide diuretic, hydrochlorothiazide.
Actelsar HCT je kombinacija antagonista receptora angiotenzina II, telmisartana i tiazidskog diuretika, hidroklorotiazida.
Blood creatinine increased, blood creatine phosphokinase increased, hepatic enzyme increased
Povišene vrijednosti kreatinina u krvi, povišene vrijednosti kreatin fosfokinaze, povišene vrijednosti jetrenih enzima
Angiotensin II receptor antagonists should not be initiated during pregnancy.
Trudnoća Primjena antagonista receptora angiotenzina II ne smije se započinjati u trudnoći.
Angioedema (also with fatal outcome), erythema, pruritus, rash, hyperhidrosis, urticaria
Angioedem (također s fatalnim ishodom), eritem, pruritus, osip,
Hypokalaemia may result in muscle spasms and/or accentuate arrhythmia associated with the concomitant use of digitalis glycosides or certain anti-arrhythmic medicinal products.
Hipokalemija može rezultirati grčevima mišića i/ili izraženom aritmijom povezanom s istodobnom primjenom glikozida digitalisa ili određenih antiaritmika.
Hypoglycaemia (in diabetic patients)
Hipoglikemija (kod dijabetičara)
Presumably through blockade of the reninangiotensin-aldosterone system, co-administration of telmisartan tends to reverse the potassium loss associated with these diuretics.
Pretpostavlja se da putem blokade sustava renin-angiotenzin-aldosteron, istodobna primjena telmisartana ima tendenciju smanjenja gubitka kalija povezanog s ovim diureticima.
Adverse reactions have been ranked under headings of frequency using the following convention: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to
Nuspojave su klasificirane po učestalosti koristeći sljedeću podjelu: vrlo često (≥1/10); često (≥1/100 i
Serious angioedema may occur rarely
Ozbiljni angioedem može se pojaviti rijetko (≥1/10 000
- Severe renal impairment (creatinine clearance <30 ml/min).
- Teško oštećenje funkcije bubrega (klirens kreatinina <30 ml/min).
The hazard ratio for telmisartan vs. ramipril was 1.01 (97.5% CI 0.93-1.10, p (non-inferiority)=0.0019 at a margin of 1.13).
Omjer rizika za telmisartan naspram ramiprila bio je 1,01 (97,5% CI 0,93-1,10, p (za neinferiornost) = 0,0019 na margini od 1,13).
Possible preventive measures such as limited exposure to sunlight and UV rays and, in case of exposure, adequate protection should be advised to the patients in order to minimize the risk of skin cancer.
Bolesnicima je potrebno savjetovati moguće preventivne mjere kao što je ograničena izloženost sunčevoj svjetlosti i UV zrakama i, u slučaju izloženosti, odgovarajuća zaštita,
PARTICULARS TO APPEAR ON THE OUTER PACKAGING Carton for Al/Al blister
PODACI KOJI SE MORAJU NALAZITI NA VANJSKOM PAKIRANJU Kutija za Al/Al blister
Toxicological findings also well known from preclinical studies with angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists were: a reduction of red cell parameters (erythrocytes, haemoglobin, haematocrit), changes of renal haemodynamics (increased blood urea nitrogen and creatinine), increased plasma renin activity, hypertrophy/hyperplasia of the juxtaglomerular cells and gastric mucosal injury.
Toksikološki nalazi također dobro poznati iz pretkliničkih studija s inhibitorima enzima koji pretvara angiotenzin i s antagonistima receptora angiotenzina II bili su: smanjenje parametara crvenih krvnih stanica (eritrociti, hemoglobin, hematokrit), promjene u bubrežnoj hemodinamici (povišeni dušik iz uree u krvi (BUN - engl. blood urea nitrogen) i kreatinin), povećana aktivnost renina u plazmi, hipertrofija/hiperplazija jukstaglomerularnih stanica i ozljeda želučane sluznice.
There was no evidence for benefit on cardiovascular mortality (hazard ratio 1.03, 95 % CI 0.85 - 1.24).
Nije bilo dokaza pozitivnih učinaka na kardiovaskularnu smrtnost (omjer rizika 1,03, 95% CI 0,85-1,24).
The concomitant use of Actelsar HCT with aliskiren-containing products is contraindicated in patients with diabetes mellitus or renal impairment (GFR <60 ml/min/1.73 m2) (see sections 4.5 and 5.1).
Istodobna primjena lijeka Actelsar HCT s lijekovima koji sadrže aliskiren kontraindicirana je u bolesnika sa šećernom bolešću ili oštećenjem funkcije bubrega (GFR<60 ml/min/1,73 m2) (vidjeti dijelove 4.5 i 5.1).
With hydrochlorothiazide, onset of diuresis occurs in 2 hours, and peak effect occurs at about 4 hours, while the action persists for approximately 6-12 hours.
Uz hidroklorotiazid, početak diureze javlja se za 2 sata, a vršni učinak pojavljuje se nakon otprilike 4 sata,
pentamidine, sparfloxacine, terfenadine, vincamine IV)
sparfloksacin, terfenadin, vinkamin i.v.)
The all-cause mortality rate was 11.6 % and 11.8 % among telmisartan and ramipril treated patients, respectively.
11,6% među bolesnicima liječenih telmisartanom i 11,8% među bolesnicima liječenih ramiprilom.
Periodic monitoring of serum potassium and ECG is recommended when Actelsar HCT is administered with medicinal products affected by serum potassium disturbances (e.g. digitalis glycosides, antiarrhythmics) and the following torsades de pointes inducing medicinal products (which include some antiarrhythmics), hypokalaemia being a predisposing factor to torsades de pointes.
Preporučuje se periodično praćenje kalija u serumu i EKG kada se Actelsar HCT uzima s lijekovima na koje utječu poremećaji kalija u serumu (npr. glikozidi digitalisa, antiaritmici) i sljedećim lijekovima koji induciraju torsades de pointes (što uključuje pojedine antiaritmike), s hipokalemijom kao predisponirajućim faktorom za torsades de pointes.
Tablet 30 tablets 90 tablets 250 tablets
Tableta 30 tableta 90 tableta 250 tableta
Actelsar HCT is not indicated in patients with severe hepatic impairment.
Actelsar HCT nije indiciran kod bolesnika s teškim oštećenjem funkcije jetre.
Infections and infestations Uncommon:
Infekcije i infestacije Rijetko:
Previous preclinical safety studies performed with co-administration of telmisartan and hydrochlorothiazide in normotensive rats and dogs, in doses producing exposure comparable to that in the clinical therapeutic range, caused no additional findings not already observed with administration of either substance alone.
Prethodne pretkliničke studije o sigurnosti izvedene pri istodobnoj primjeni telmisartana i hidroklorotiazida na normotenzivnim štakorima i psima u dozama koje dovode do izloženosti usporedivoj s onim u kliničkom terapijskom rasponu nisu dale dodatna otkrića koja već ranije nisu bila primijećena u primjeni svake tvari zasebno.
Due to the hydrochlorothiazide component, markedly low blood pressure and low blood levels of potassium can also happen, which may result in nausea, sleepiness and muscle cramps and/or irregular heartbeat associated with the concomitant use of medicinal products such as digitalis or certain anti-arrhythmic treatments.
Zbog hidroklorotiazida kao komponente, također može doći i do izrazitije niskog krvnog tlaka i niskih vrijednosti kalija u krvi, što može rezultirati mučninom, pospanošću i grčevima mišića i/ili nepravilnim otkucajima srca povezanim s istodobnom primjenom lijekova kao što su digitalis ili određeni antiaritmici.
Exposure to angiotensin II receptor antagonist therapy during the second and third trimesters is known to induce human fetotoxicity (decreased renal function, oligohydramnios, skull ossification retardation) and neonatal toxicity (renal failure, hypotension, hyperkalaemia) (see section 5.3).
Poznato je da izloženost terapiji antagonistom receptora angiotenzina II tijekom drugog i trećeg tromjesečja inducira fetotoksičnost u ljudi (smanjena bubrežna funkcija, oligohidramnion, kašnjenje osifikacije lubanje) kao i neonatalnu toksičnost (zatajenje bubrega, hipotenzija, hiperkalemija) (vidjeti dio 5.3).
In patients taking hydrochlorothiazide alone the following additional side effects have been reported:
Kod bolesnika koji uzimaju monoterapiju hidroklorotiazida prijavljene su sljedeće dodatne nuspojave.
Abdominal pain, constipation, dyspepsia, vomiting, gastritis
Bol u abdomenu, konstipacija, dispepsija, povraćanje, gastritis
Common (may affect up to 1 in 10 people): Dizziness
Često (mogu se javiti u do 1 na 10 osoba): Omaglica
Neoplasms benign, malignant and unspecified (incl cysts and polyps) Not known
Dobroćudne, zloćudne i nespecificirane novotvorine (uključujući ciste i polipe)
- Other medicines used to treat high blood pressure, corticosteroids, painkillers (such as nonsteroidal anti-inflammatory drugs [NSAIDs]), medicines to treat cancer, gout, or arthritis.
- drugi lijekovi koji se primjenjuju u liječenju visokog krvnog tlaka, kortikosteroidi, lijekovi protiv bolova (kao što su nesteroidni protuupalni lijekovi [NSAIL-ovi]), lijekovi za liječenje raka, gihta, ili artritisa.
- Medicines for the treatment of diabetes (insulins or oral agents such as metformin).
- lijekovi za liječenje dijabetesa (inzulini ili lijekovi koji se primjenjuju kroz usta kao što je metformin).
Xanthopsia, acute myopia, acute angle-closure glaucoma
Ksantopsija, akutna miopija, akutni glaukom zatvorenog kuta
For Al/Al blisters and HDPE tablet container: 2 years.
Za Al/Al blistere i HDPE spremnik s tabletama: 2 godine.
In patients with mild to moderate hepatic impairment the posology should not exceed Actelsar HCT 40 mg/12.5 mg once daily.
Kod bolesnika s blagim do umjerenim oštećenjem funkcije jetre doza ne smije prelaziti Actelsar HCT 40 mg/12,5 mg jedanput dnevno.
Syncope, paraesthesia
Sinkopa, parestezija
Some people feel dizzy or tired when taking Actelsar HCT.
Neke osobe mogu osjećati omaglicu ili umor tijekom primjene Actelsara HCT.
PARTICULARS TO APPEAR ON THE INNER PACKAGING Label for HDPE tablet container
PODACI KOJI SE MORAJU NALAZITI NA UNUTARNJEM PAKIRANJU Naljepnica za HDPE spremnik s tabletama
There is no clinical experience with Actelsar HCT in patients with hepatic impairment.
Nema kliničkog iskustva s Actelsarom HCT kod bolesnika s oštećenjem funkcije jetre.
Food slightly reduces the bioavailability of telmisartan with a reduction in the area under the plasma concentration time curve (AUC) of about 6% with the 40 mg tablet and about 19% after a 160 mg dose.
Hrana u vrlo maloj mjeri reducira bioraspoloživost telmisartana, s redukcijom površine ispod krivulje plazmatske koncentracije u odnosu na vrijeme (AUC) od oko 6% uz tabletu od
In case of surgery or anaesthetics, you should tell your doctor that you are taking Actelsar HCT.
Ako trebate na operaciju ili primati anestetik, morate biti sigurni da Vaš liječnik zna da uzimate
- class Ia antiarrythmics (e.g. quinidine, hydroquinidine, disopyramide) - class III antiarrythmics (e.g. amiodarone, sotalol, dofetilide, ibutilide) - some antipsychotics (e.g. thioridazine, chlorpromazine, levomepromazine, trifluoperazine,
- skupina Ia antiaritmika (npr. kinidin, hidrokinidin, disopiramid) - skupina III antiaritmika (npr. amiodaron, sotalol, dofetilid, ibutilid) - neki antipsihotici (npr. tioridazin, klorpromazin, levomepromazin, trifluoperazin, cijamemazin,
When pregnancy is diagnosed, treatment with angiotensin II receptor antagonists should be stopped immediately, and if appropriate, alternative therapy should be started.
Kada se trudnoća dijagnosticira, liječenje antagonistima receptora angiotenzina II mora se trenutno prekinuti, te, prema potrebi, početi sa zamjenskom terapijom.
Actelsar HCT 40 mg/12.5 mg tablets EU/1/13/817/043
Actelsar HCT 40 mg/12,5 mg tablete EU/1/13/817/043
Telmisartan Adverse reactions occurred with similar frequency in placebo and telmisartan treated patients.
Nuspojave su se pojavljivale s istom učestalošću kod osoba liječenih placebom i telmisartanom.
Sodium starch glycolate (type A) Microcrystalline cellulose Mannitol (E421)
celuloza, mikrokristalična manitol (E421)
ACE-inhibitors and angiotensin II receptor blockers should not be used concomitantly in patients with diabetic nephropathy.
inhibitori i blokatori angiotenzin II receptora ne smiju se primjenjivati istodobno u bolesnika s dijabetičkom nefropatijom.
Actelsar HCT 80 mg/12.5 mg tablets EU/1/13/817/014
Actelsar HCT 80 mg/12,5 mg tablete EU/1/13/817/014
How to take Actelsar HCT
Kako uzimati Actelsar HCT
Hypersensitivity, anaphylactic reactions Metabolism and nutrition disorders Uncommon:
Preosjetljivost, anafilaktičke reakcije Poremećaji metabolizma i prehrane Manje često: