natgillin/translations-raw huggingface dataset:
However, acidic drinks, e.g. orange juice, should generally be avoided as the powder tends not to mix well and may precipitate out.
Međutim, kisela pića, npr. sok od naranče, treba općenito izbjegavati jer se prah s njima ne pomiješa dobro već može ostati u talogu.
- Your or your child's medical treatment may include, in addition to CYSTAGON, one or more supplements to replace important electrolytes lost through the kidneys.
- Liječenje Vas ili Vašeg djeteta može uključivati, uz CYSTAGON, jedan ili više nadomjestaka koji zamjenjuju važne elektrolite izgubljene bubrezima.
Your doctor could require a regular physical and X-ray examination for the skin and the bones to control the effects of the medicinal product.
Vaš liječnik može zahtijevati redoviti fizikalni i rendgenski pregled kože i kostiju radi kontrole učinaka ovog lijeka.
Approximately 35% of patients can be expected to experience adverse reactions.
Očekuje se da oko 35% bolesnika razvije nuspojave.
Patients on treatment maintained growth as compared to untreated patients.
Liječeni bolesnici održali su rast usporediv s neliječenim bolesnicima.
The consequence of this for the clinical use of the drug is unknown.
Posljedice ovoga, za kliničku upotrebu lijeka nisu poznate.
Intact CYSTAGON hard capsules should not be administered to children under the age of approximately 6 years due to risk of aspiration (see section 4.2).
Neotvorene CYSTAGON tvrde kapsule ne treba davati djeci mlađoj od 6 godina zbog rizika aspiracije (vidjeti dio 4.2).
When these effects appear at the initiation of cysteamine therapy, temporary suspension and gradual reintroduction of treatment may be effective in improving tolerance.
Kada se ove nuspojave pojave na početku terapije cisteaminom, privremena obustava i postupno ponovno uvođenje terapije može pomoći u poboljšanju tolerancije.
Make sure you know how you or your child reacts to this medicine before doing anything that could be dangerous if not alert.
Provjerite kako Vi ili Vaše dijete reagirate na ovaj lijek prije nego što učinite bilo što, što bi moglo biti opasno ako Vam je smanjena pozornost.
Regular blood and urine tests to measure the levels of the body's important electrolytes are also necessary to help your or your child's doctor correctly adjust the doses of these supplements.
Redovite pretrage krvi i mokraće radi mjerenja razine elektrolita važnih za tijelo također su nužne da bi pomogle Vašem liječniku ili liječniku Vašeg djeteta da prilagodi doze ovih nadomjestaka.
If any skin or bone abnormalities appear, please inform your doctor immediately.
Ukoliko se pojave bilo kakve abnormalnosti kože ili kostiju, molimo Vas da odmah obavijestite svojeg liječnika.
The principal efficacy measurements were serum creatinine and calculated creatinine clearance and growth (height).
Osnovne mjere djelotvornosti bile su kreatinin u serumu te izračunat klirens kreatinina i rast (visina).
The WBC levels should be measured 5 to 6 hours after dosing and should be checked frequently when initiating therapy (e.g. monthly) and every 3-4 months when on a stable dose.
Razinu u leukocitima treba mjeriti 5 do 6 sati nakon uzimanja doze te ju treba pri uvođenju terapije često provjeravati (npr. svaki mjesec), a kada se postigne stabilna doza, treba provjeravati svaka 3-4 mjeseca.
The recommended dose is 1.30 g/m 2/day of the free base divided four times daily.
Preporučena doza je 1,30 g/m2/dan slobodne baze podijeljene u četiri puta na dan.
Read all of this leaflet carefully before you start using this medicine.
Pažljivo pročitajte cijelu uputu prije nego počnete primjenjivati lijek.
Among cysteamine patients, glomerular function was maintained over time.
Među bolesnicima koji su primali cisteamin, glomerularna funkcija je održana tijekom vremena.
Self examination of your or your child's skin is recommended.
Preporuča se samopregled Vaše kože ili kože Vašeg djeteta.
Patients with hepatic insufficiency: Dose adjustment is not normally required; however, leucocyte cystine levels should be monitored.
Bolesnici sa insuficijencijom jetre: Prilagodba doze obično nije potrebna; međutim, treba pratiti razinu cistina u leukocitima.
Date of latest renewal: 23 June 2007.
Datum posljednje obnove: 23. lipanj 2007.
Do not use CYSTAGON - if you -or your child- are allergic (hypersensitive) to cysteamine bitartrate or penicillamine or any of the other ingredients of Cystagon.
Nemojte primjenjivati CYSTAGON - ako ste Vi ili Vaše dijete alergični (preosjetljivi) na cisteaminditartrat ili penicilamin ili bilo koji drugi sastojak lijeka Cystagon.
It is important to take the dose as close to every 6 hours as possible.
Važno je uzimati doze u razmacima od približno svakih 6 sati.
These mainly involve the gastrointestinal and central nervous systems.
One uglavnom uključuju probavni i središnji živčani sustav.
- To avoid any risk of aspiration in the lungs, the capsules should not be given to children under the age of approximately 6 years.
- Da bi se izbjegao rizik slučajnog udisanja u pluća, kapsule se ne smiju davati djeci mlađoj od približno 6 godina.
Like all medicines, CYSTAGON can cause side effects, although not everybody gets them.
Kao i svi drugi lijekovi, CYSTAGON može uzrokovati nuspojave, iako se one neće pojaviti kod svih osoba.
In a pharmacokinetic study performed in 24 healthy volunteers for 24 hours, the mean estimate ( sd) for the terminal half-life of elimination was 4.8 ( 1.8) hours.
U farmakokinetičkom ispitivanju provedenom na 24 zdrava dobrovoljca kroz 24 sata, procijenjena srednja vrijednost ( sd) poluvremena eliminacije bila je 4,8 ( 1,8) sati.
If a pregnancy is diagnosed or planned, the treatment should be carefully reconsidered and the patient must be advised of the possible teratogenic risk of cysteamine.
Ukoliko se dijagnosticira trudnoća ili se ona planira, treba pažljivo razmotriti potrebu za liječenjem, a bolesnicu upoznati s mogućim teratogenim rizikom cisteamina.
A desiccant unit containing black activated carbon and silica gel granules is included in the bottle.
Sredstvo za sušenje koje sadrži crni aktivni ugljen i granule silikagela umetnuto je u bočicu.
Uncommon: Nervousness, hallucination
Manje često: Nervoza, halucinacija
In all studies, patient response was better when treatment was started at an early age with good renal function.
U svim ispitivanjima, odgovor bolesnika bio je bolji kada se liječenje započelo u ranoj dobi uz dobru funkciju bubrega.
CYSTAGON may cause some people to become drowsy or less vigilant than they are normally.
CYSTAGON može kod nekih ljudi dovesti do pospanosti ili slabije pažnje nego što je za njih normalno.
Self-examination of the skin by the patient or the parents should also be advised.
Također treba bolesnicima ili roditeljima savjetovati samopregled kože.
Always use CYSTAGON exactly as your doctor or your child's doctor has told you.
Uvijek primjenite CYSTAGON točno onako kako Vam je rekao Vaš liječnik ili liječnik Vašeg djeteta.
If several doses of the supplements are missed or weakness or drowsiness develops, call the doctor for instructions.
Ukoliko propustite nekoliko doza ovih nadomjestaka ili dođe do slabosti i umora, nazovite svog liječnika radi uputa.
CYSTAGON is a medicine that reacts with cystine to decrease its level within the cells.
CYSTAGON je lijek koji reagira s cistinom da bi smanjio njegovu razinu unutar stanica.
The following side effects were reported as follows: very common (occurring in at least one in 10 patients), common (occurring in at least one in 100 patients), uncommon (occurring in at least one in1,000 patients), rare (occurring in at least one in 10,000 patients), very rare (occurring in at least one in 100,000 patients).
Sljedeće nuspojave zabilježene su kako slijedi: vrlo često (pojavljuju se kod najmanje 1 na 10 bolesnika), često (pojavljuju se kod najmanje 1 na 100 bolesnika), manje često (pojavljuju se kod najmanje 1 na 1000 bolesnika), rijetko (pojavljuju se kod najmanje 1 na 10 000 bolesnika), vrlo rijetko (pojavljuju se kod najmanje 1 na 100 000 bolesnika).
No carcinogenic studies have been conducted with CYSTAGON.
Nisu provedena ispitivanja kancerogenosti sa CYSTAGONOM.
Date of first authorisation: 23 June 1997.
Datum prvog odobrenja: 23. lipanj 1997.
CYSTAGON is prescribed to manage this rare inherited disorder.
CYSTAGON se propisuje za liječenje ovog rijetkog nasljednog poremećaja.
Do not store above 25°C and keep the container tightly closed in order to protect from light and moisture.
Nemojte čuvati na temperaturi iznad 25°C te spremnik čuvajte čvrsto zatvoren radi zaštite od svjetlosti i vlage.
When starting therapy, patients should not engage in potentially hazardous activities until the effects of the medicinal product on each individual are known.
Pri započinjanju terapije, bolesnici se ne smiju upuštati u potencijalno opasne aktivnosti sve dok se ne vidi učinak ovog lijeka na svakog pojedinca.
- Hard capsules should not be given to children under approximately six years of age because they may not be able to swallow them and they may choke.
- Tvrde kapsule ne smiju se davati djeci mlađoj od šest godina jer ih ona možda neće biti sposobna progutati te se mogu ugušiti.
In contrast to phosphocysteamine, CYSTAGON does not contain phosphate.
Za razliku od fosfocisteamina, CYSTAGON ne sadrži fosfat.
The elimination of unchanged cysteamine in the urine has been shown to range between 0.3 % and 1.7% of the total daily dose in four patients; the bulk of cysteamine is excreted as sulphate.
Pokazalo se da je eliminacija nepromijenjenog cisteamina urinom u rasponu od 0,3 % i 1,7% ukupne dnevne doze kod četiri bolesnika; većina cisteamina se izlučuje u obliku sulfata.
Therefore, CYSTAGON should not be used during pregnancy, particularly during the first trimester, unless clearly necessary.
Stoga, se CYSTAGON ne smije primjenjivati tijekom trudnoće, osobito u prvom tromjesečju, ukoliko nije neophodno.
When starting therapy, you or your child should not engage in potentially hazardous activities until the effects of the drug are well known.
Prilikom započinjanja terapije, Vi i Vaše dijete ne biste se trebali upuštati u potencijalno opasne aktivnosti sve dok nisu dobro poznati učinci lijeka.
Frequencies are defined as: very common (≥ 1/10), common (≥1/100 to 1/10) and uncommon (≥1/1,000 to 1/100).
Učestalost je definirana prema sljedećim kategorijama: vrlo često (≥ 1/10), često (≥ 1/100 i < 1/10) te manje često (≥ 1/1000 i < 1/100).
Should overdosage occur, the respiratory and cardiovascular systems should be supported appropriately.
Ukoliko dođe do predoziranja, treba dati suportivnu terapiju dišnog i kardiovaskularnog sustava.
Placebo treated patients, in contrast, experienced a gradual rise in serum creatinine.
Suprotno toga, bolesnici koji su primali placebo doživjeli su postupni porast kreatinina u serumu.
Using CYSTAGON with food and drink
Uzimanje hrane i pića s CYSTAGONom
Within each frequency grouping, undesirable effects are presented in order of decreasing seriouness
Unutar svake skupine učestalosti, nuspojave su prikazane u padajućem nizu prema ozbiljnosti.
Your or your child's doctor will arrange for the blood tests to be done.
Vaš liječnik ili liječnik Vašeg djeteta organizirat će ove pretrage.
CYSTAGON can be administered with electrolyte and mineral replacements necessary for management of the Fanconi syndrome as well as vitamin D and thyroid hormones.
CYSTAGON se može primjenjivati zajedno s nadomjescima za elektrolite i minerale koji su potrebni za liječenje Fanconijevog sindroma kao i s vitaminom D i hormonima štitnjače.
Pharmacotherapeutic group: Alimentary tract and metabolism product, ATC code: A16AA04.
Farmakoterapijska skupina: Lijekovi za probavni sustav i metabolizam, ATK oznaka: A16AA04.
Renal tubular function was not affected by treatment.
Liječenje nije utjecalo na renalnu tubularnu funkciju.
Cystinosis is a metabolic disease called ‘nephropathic cystinosis' which is characterized by an abnormal accumulation of the amino acid cystine in various organs of the body such as the kidney, eye, muscle, pancreas, and brain.
Cistinoza je metabolička bolest zvana 'nefropatska cistinoza' koju karakterizira abnormalno nakupljanje aminokiseline cistina u raznim tjelesnim organima poput bubrega, oka, mišića, gušterače i mozga.
Take special care with CYSTAGON - When your or your child's disorder has been confirmed by leucocyte cystine measurements, the therapy with CYSTAGON must be started as soon as possible.
Budite posebno oprezni s CYSTAGONom - Kada je mjerenjem cistina u leukocitima kod Vas ili Vašeg djeteta potvrđen poremećaj, liječenje Cystagonom mora se započeti što je ranije moguće.
For children under approximately six years of age, the hard capsule may be opened and the contents sprinkled on food (e.g. milk, potatoes or starch based foods) or mixed in formula.
Za djecu mlađu od šest godina starosti, tvrda se kapsula može otvoriti i sadržaj posuti po hrani (npr. mlijeku, krumpirima ili namirnicama na bazi škroba) ili pomiješati u formulu.
CYSTAGON is contraindicated in patients who have developed hypersensitivity to penicillamine.
CYSTAGON je kontraindiciran kod bolesnika koji su razvili preosjetljivost na penicilamin.
Therefore, where cysteamine ophthalmic solution is used for that purpose, its usage should continue.
Stoga, kada se za tu svrhu koristi oftalmološka otopina, njenu upotrebu treba nastaviti.
One patient subsequently died of acute cerebral ischemia with marked vasculopathy.
Jedan je bolesnik posljedično umro od akutne cerebralne ishemije s izraženom vaskulopatijom.
Cysteamine mechanism of action by interfering with the cross-linking of collagen fibers has been postulated (see section 4.4).
Pretpostavlja se da je mehanizam djelovanja cisteamina ometanje križnog povezivanja kolagenskih vlakana (vidjeti dio 4.4).
The mixed disulfide is then exported from the lysosomes by an intact lysine transport system.
Miješani disulfid se zatim prenosi iz lizosoma putem neoštećenog transportnog sustava za lizin.
No information is available for patients with severe renal insufficiency.
Nisu dostupni podaci za bolesnike s teškom insuficijencijom bubrega.
The maximum dose of CYSTAGON used in clinical trials was 1.95 g/m2/day.
Maksimalna doza CYSTAGONA korištena u kliničkim ispitivanjima bila je 1,95 g/m2/dan.
Detailed information on this product is available on the website of the European Medicines Agency (EMA) http://www.ema.europa.eu
Podrobnije informacije o ovom lijeku dostupne su na web stranicama Europske agencije za lijekove (EMA) http://www.ema.europa.eu.
For children up to age 12 years, the dose will be based on the body size (surface area), the usual dose being 1.30 g/m2 of body surface area per day.
Za djecu do 12 godina, doza će se temeljiti na veličini tijela (površini) te će uobičajena doza biti 1,30 g/m tjelesne površine na dan.
However, due to the results of animal studies in breast-feeding mothers and neonates (see section 5.3), breast-feeding is contra-indicated in women taking CYSTAGON.
Međutim, zbog rezultata ispitivanja provedenih na životinjama koje su dojile i njihovoj mladunčadi (vidjeti dio 5.3), dojenje je kontraindicirano u žena koje uzimaju CYSTAGON.
Cystine build up causes kidney damage and excretion of excess amounts of glucose, proteins and electrolytes.
Nagomilani cistin dovodi do oštećenja bubrega i izlučivanja prekomjernih količina glukoze, proteina i elektrolita.
100 hard capsules (with a desiccant unit in the bottle) 500 hard capsules (with a desiccant unit in the bottle)
100 tvrdih kapsula (sa sredstvom za sušenje u bočici) 500 tvrdih kapsula (sa sredstvom za sušenje u bočici)
Very limited data suggest that cysteamine pharmacokinetic parameters may not be significantly modified in patients with mild to moderate renal insufficiency.
Vrlo ograničeni podaci upućuju na to da farmakokinetički parametri cisteamina nisu značajno promijenjeni kod bolesnika s blagim do umjerenim zatajenjem bubrega.
- Your doctor could require controlling the blood cell count on a regular basis.
- Vaš liječnik može zahtijevati redovitu kontrolu krvne slike.
There are no adequate data from the use of cysteamine bitartrate in pregnant women.
Ne postoje adekvatni podaci o primjeni cisteamin bitartrata u trudnica.
A reduction of fertility was observed in rats at 375 mg/kg/day, a dose at which body weight gain was retarded.
Kod štakora je zabilježeno smanjenje fertiliteta pri 375 mg/kg/dan, dozi pri kojoj je bio usporen prirast tjelesne težine.
Bottles of 100 or 500 hard capsules.
Bočice sa 100 ili 500 tvrdih kapsula.
Nephropathic cystinosis must have been diagnosed by both clinical signs and biochemical investigations (leucocyte cystine measurements).
Nefropatska cistinoza mora biti dijagnosticirana na temelju i kliničkih znakova i biokemijskih pretraga (mjerenja cistina u leukocitima).
Teratogenic effects have been described in rats when cysteamine is administered over the period of organogenesis at a dose of 100 mg/kg/day.
Teratogeni učinci su opisani kod štakora kada je cisteamin primijenjen tijekom razdoblja organogeneze u dozi od 100 mg/kg/dan.
Cases of nephrotic syndrome have been reported within 6 months of starting therapy with progressive recovery after treatment discontinuation.
Zabilježeni slučajevi nefrotskog sindoma unutar 6 mjeseci od započinjanja terapije s progresivnim oporavkom nakon prekida liječenja.
CYSTAGON therapy must be initiated promptly after confirmation of the diagnosis of nephropathic cystinosis to achieve maximum benefit.
Liječenje CYSTAGONOM treba započeti odmah nakon potvrde dijagnoze nefropatske cistinoze kako bi se postigla maksimalna korist.
CYSTAGON should be taken or given only by mouth and exactly as your or your child's doctor directs.
CYSTAGON treba uzimati ili davati samo na usta i točno kako Vam je Vaš liječnik ili liječnik Vašeg djeteta odredio.
Genotoxicity studies have been performed: although in published studies using cysteamine, induction of chromosome aberrations in cultured eukaryotic cell lines has been reported, specific studies with cysteamine bitartrate did not show any mutagenic effects in the Ames test or any clastogenic effect in the mouse micronucleus test.
Provedena su ispitivanja genotoksičnosti: iako je u objavljenim ispitivanjima s cisteaminom zabilježeno izazivanje kromosomskih aberacija u kulturama eukariotskih staničnih linija, specifična ispitivanja s cisteamin bitartratom nisu pokazala mutagene učinke u Amesovom testu ili bilo kakav klastogeni učinak u mikronukleus testu na mišu.
In any case the usual dose should not exceed 1.95 g/m2/day.
U nijednom slučaju doza ne smije prelaziti 1,95 g/m2/dan.
This is equivalent to 0.6 g/m2/day in the rat, which is less than half the recommended clinical maintenance dose of cysteamine, i.e. 1.30 g/ m2/day.
Ovo je ekvivalentno dozi od 0,6 g/m2/dan kod štakora, što je manje od polovice preporučene kliničke doze održavanja za cisteamin, tj. 1,30 g/ m2/dan.
The plasma protein binding in patients at steady state is similar: 53.1 % ( 3.6) and 51.1 % ( 4.5) at 1.5 and 6 hours post-dose, respectively.
Vezanje za proteine plazme kod bolesnika u stanju dinamičke ravnoteže je slično: 53,1 % ( 3,6) odnosno 51,1 % ( 4,5) nakon 1,5 odnosno 6 sati od primjene doze.
Digestive tolerance of cysteamine is improved when the medicinal product is taken just after or with food.
Podnošenje cisteamina od strane probavnog sustava poboljšano je kada se ovaj lijek uzima neposredno nakon ili tijekom obroka.
Indomethacin and CYSTAGON have been used simultaneously in some patients.
U nekih su bolesnika istodobno korišteni indometacin i CYSTAGON.
In cases where histopathological examination of the skin was performed, the results suggested angioendotheliomatosis.
U slučajevima u kojim je proveden histopatološki pregled kože, rezultati su upućivali na angioendoteliomatozu.
In cases of patients with kidney transplants, anti-rejection treatments have been used with cysteamine.
U bolesnika s transplantiranim bubrezima, terapija protiv odbacivanja transplantata korištena je s cisteaminom.
- Regular blood tests to measure the amount of cystine inside white blood cells are necessary to help determine the correct dose of CYSTAGON.
- Neophodne su redovite krvne pretrage radi mjerenja cistina unutar leukocita da bi pomogle odrediti ispravnu dozu Cystagona.
Keep the container tightly closed in order to protect from light and moisture
Spremnik čuvati čvrsto zatvoren radi zaštite od svjetlosti i vlage.
• For patients over age 12 and over 50 kg weight, the recommended CYSTAGON dose is 2 g/day, divided four times daily.
• Za bolesnike iznad 12 godina i preko 50 kg tjelesne težine, preporučena doza CYSTAGONA je 2 g/dan, podijeljena u četiri puta na dan.
If any similar skin or bone abnormalities appear, it is recommended to decrease the dose of CYSTAGON.
Ukoliko se pojave bilo koje slične abnormalnosti kože ili kostiju, preporučuje se smanjiti dozu CYSTAGONA.
You may already be receiving phosphate supplements and the dose of these may need to be changed when CYSTAGON is substituted for phosphocysteamine.
Možda već primate nadomjestke fosfata te će njihovu dozu možda trebati promijeniti kada se CYSTAGON zamijeni fosfocisteaminom.
In children who are at risk of aspiration, aged approximately 6 years and under, the hard capsules should be opened and the content sprinkled on food.
U djece kod koje postoji rizik od aspiracije, u dobi oko 6 godina i mlađe, tvrde kapsule treba otvoriti, a sadržaj posipati po hrani.
The leucocyte cystine level reaches its minimum (mean ( sd) value: 1.8  0.8 hours) slightly later than the peak plasma cysteamine concentration (mean ( sd) value: 1.4  0.4 hours) and returns to its baseline level as the plasma cysteamine concentration decreases at 6 hours post-dose.
Razina cistina u leukocitima postiže svoj minimum (srednja vrijednost ( sd): 1,8  0,8 sati) nešto kasnije od postizanja vršne koncentracije cisteamina u plazmi (srednja vrijednost ( sd): 1,4  0,4 sati) te se vraća na bazalnu razinu kako se koncentracija cisteamina u plazmi smanji 6 sati nakon uzete doze.
At this dose, weight gain and survival of the offspring during lactation was also reduced.
Pri ovoj dozi, također su bili smanjeni prirast tjelesne težine te preživljavanje potomaka tijekom dojenja.
Common: Headache, encephalopathy Uncommon: Somnolence, convulsions
Često: Glavobolja, encefalopatija Manje često: Somnolencija, konvulzije
An earlier study treated 94 children with nephropathic cystinosis with increasing doses of cysteamine to attain white cell cystine levels of less than 2 nmol hemicystine/mg protein 5 to 6 hours post-dose, and compared their outcome with an historical control group of 17 children treated with placebo.
U ranijoj studiji 94 djece s nefropatskom cistinozom liječeno je rastućim dozama cisteamina da bi se održala razina cistina u leukocitima ispod 2 nmol hemicistina/mg proteina 5 do 6 sati nakon uzimanja doze te je ishod kod njih uspoređen s povijesnom kontrolnom skupinom od 17-tero djece koja su primala placebo.
Cysteamine reduces cystine accumulation in some cells (e.g. leukocytes, muscle and liver cells) of nephropathic cystinosis patients and, when treatment is started early, it delays the development of renal failure.
Cisteamin smanjuje nakupljanje cistina u nekim stanicama (npr. leukocitima, mišićnim i jetrenim stanicama) kod bolesnika s nefropatskom cistinozom te, ukoliko je liječenje rano započeto, odgađa nastanak zatajenja bubrega.
High doses of cysteamine impair the ability of lactating mothers to feed their pups.
Visoke doze cisteamina oštećuju sposobnost ženki u laktaciji da hrane svoje mladunce.
It is not known if cysteamine is removed by haemodialysis.
Nije poznato da li se cisteamin odstranjuje hemodijalizom.
In one clinical study, baseline white cell cystine levels were 3.73 (range 0.13 to 19.8) nmol hemicystine/mg protein and were maintained close to 1 nmol hemicystine/mg protein with a cysteamine dose range of 1.3 to 1.95 g/m2/day.
U jednom kliničkom ispitivanju, bazalna razina cistina u leukocitima iznosila je 3,73 (raspon 0,13 do 19,8) nmol hemicistina/mg proteina te je održavana blizu 1 nmol hemicistina/mg proteina uz raspon doza cisteamina od 1,3 do 1,95 g/m2/dan.
CYSTAGON may cause some drowsiness.
CYSTAGON može dovesti do pospanosti.