natgillin/translations-raw huggingface dataset:
This includes fractures (breaks in the bone), spinal compression (when the spinal cord is compressed by the bone), bone disorders needing radiotherapy (treatment with radiation) or surgery, and hypercalcaemia (high levels of calcium in the blood).
Ovo uključuje frakture (pucanje kosti), spinalnu kompresiju (kada kost komprimira kralježničku moždinu), koštane poremećaje koji zahtijevaju radioterapiju (liječenje zračenjem) ili kirurški zahvat te hiperkalkemiju (visoke razine kalcija u tijelu).
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Zoledronic Acid Hospira.
Objašnjava kako je Povjerenstvo za lijekove za primjenu kod ljudi (CHMP) ocijenilo lijek da bi donijelo svoje mišljenje u korist izdavanja odobrenja za stavljanje lijeka u promet i svoje preporuke u vezi s uvjetima za uporabu za Zoledronatnu kiselinu Hospira.
By preventing the breakdown of bones, Zoledronic Acid Hospira also helps to reduce the amount of calcium released into the blood.
Prevenirajući razgradnju kostiju, Zoledronatna kiselina Hospira također pomaže u smanjivanju količine kalcija koji se ispušta u krv.
Patients must have adequate fluids before and after treatment, and should receive adequate supplements of vitamin D and calcium.
Bolesnici moraju uzeti primjerenu količinu tekućine prije i nakon liječenja, te moraju primiti odgovarajuće nadomjeske vitamina D i kalcija.
It is available as a concentrate (4 mg/5 ml) to be made up into a solution for infusion (drip) into a vein, and as solutions for infusion (4 mg/100 ml and 5 mg/100 ml).
Dostupan je kao koncentrat (4 mg/5 ml) za miješanje u otopinu za infuziju (drip) u venu i kao otopine za infuziju (4 mg/100 ml i 5 mg/100 ml).
For more information about treatment with Zoledronic Acid Hospira, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.
Više informacija o terapiji Zoledronatnom kiselinom Hospira pročitajte u uputi lijeka (također dio EPAR-a), odnosno obratite se svom liječniku ili ljekarniku.
The European Commission granted a marketing authorisation valid throughout the European Union for Zoledronic Acid Hospira on 19 November 2012.
Europska komisija izdala je odobrenje za stavljanje u promet koje za Zoledronatnu kiselinu Hospira vrijedi na prostoru Europske unije od 19. studenog 2012.
This is a summary of the European public assessment report (EPAR) for Zoledronic Acid Hospira.
Ovo je sažetak Europskoga javnog izvješća o ocjeni dokumentacije (EPAR) za Zoledronatnu kiselinu Hospira.
For more information on generic and hybrid medicines, see the question-and-answer document here.
Više informacija o generičkim lijekovima potražite u dokumentu s pitanjima i odgovorima ovdje.
The company provided data from the published literature on zoledronic acid.
Tvrtka je dostavila podatke iz objavljene literature koja je dostupna za zoledronatnu kiselinu.
The reduction of bone loss helps to make bones less likely to break, which is useful in preventing fractures in cancer patients with bone metastases.
Smanjenje gubitka koštane mase pomaže pri smanjivanju izgleda za pucanje kostiju, što je korisno u prevenciji fraktura u bolesnika oboljelih od raka s metastazama u kostima.
Because Zoledronic Acid Hospira is given by infusion and contains the same active substance as the reference medicines, its benefits and risks are taken as being the same as the reference medicines'.
Budući da se Zoledronatna kiselina Hospira primjenjuje infuzijom i sadrži istu djelatnu tvar kao referentni lijekovi, smatra se da su njezine koristi i rizici isti kao i oni referentnih lijekova.
No additional studies were needed as Zoledronic Acid Hospira is given by infusion and contains the same active substance as the reference medicines, Zometa and Aclasta.
Dodatna ispitivanja nisu bila potrebna budući da se Zoledronatna kiselina Hospira primjenjuje infuzijom i sadrži istu djelatnu tvar kao referenti lijekovi Zometa i Aclasta.
Zoledronic Acid Hospira is a ‘generic' and a ‘hybrid' medicine.
Zoledronatna kiselina Hospira je „generički” i „hibridni lijek”.
Zoledronic Acid Hospira 5 mg/100 ml solution is used to treat Paget's disease of the bone in adults.
Otopina Zoledronatne kiseline Hospira od 5 mg/100 ml koristi se za liječenje Pagetove bolesti kostiju u odraslih bolesnika.
For the prevention of bone complications and treatment of hypercalcaemia caused by tumours, the usual dose of Zoledronic Acid Hospira is one infusion of 4 mg over at least 15 minutes.
Za potrebe prevencije koštanih događaja i liječenje hiperkalkemije uzrokovane tumorima, uobičajena je doza Zoledronatne kiseline Hospira jedna infuzija od 4 mg koja se uzima tijekom najmanje 15 minuta.
What measures are being taken to ensure the safe and effective use of Zoledronic Acid Hospira?
Koje se mjere poduzimaju kako bi se osigurala sigurna i učinkovita primjena Zoledronatne kiseline Hospira?
A risk management plan has been developed to ensure that Zoledronic Acid Hospira is used as safely as possible.
Pripremljen je plan upravljanja rizikom kako bi se osigurala što sigurnija primjena Zoledronatne kiseline Hospira.
The CHMP concluded that, in accordance with EU requirements, Zoledronic Acid Hospira has been shown to be comparable to Zometa and Aclasta.
Povjerenstvo za lijekove za primjenu kod ljudi (CHMP) pri Agenciji zaključilo je kako je, u skladu s preduvjetima EU-a, potvrđeno da je Zoledronatna kiselina Hospira usporediva s lijekovima Zometa i Aclasta.
For the treatment of Paget's disease of the bone, Zoledronic Acid Hospira is given as one infusion lasting at least 15 minutes.
Za potrebe liječenja Pagetove bolesti kostiju, Zoledronatna kiselina Hospira primjenjuje se kao infuzija koja traje najmanje 15 minuta.
Aclasta is the reference medicine for the 5 mg/100 ml solution.
Aclasta je referentni lijek za otopinu od 5 mg/100 ml.
An additional infusion, given at least one year after the first one, can be considered if the patient's disease comes back.
Ako dođe do relapsa bolesti u bolesnika, može se razmotriti primjena dodatne infuzije, koja se primjenjuje barem godinu dana nakon prve infuzije.
The Committee recommended that Zoledronic Acid Hospira be given marketing authorisation.
Povjerenstvo je preporučilo izdavanje odobrenja za stavljanje u promet Zoledronatne kiseline Hospira.
The active substance in Zoledronic Acid Hospira, zoledronic acid, is a bisphosphonate.
Djelatna tvar Zoledronatne kiseline Hospira, zoledronatna kiselina, je bisfosfonat.
What are the benefits and risks of Zoledronic Acid Hospira?
Koje su koristi i rizici Zoledronatne kiseline Hospira?
Zoledronic Acid Hospira 4 mg/5 ml concentrate and 4 mg/100 ml solution are used to prevent bone complications in adults with advanced cancer that is affecting the bone.
Koncentrat Zoledronatne kiseline Hospira od 4 mg/5 ml i otopina Zoledronatne kiseline Hospira od 4 mg/100 ml koriste se za prevenciju koštanih događaja u odraslih bolesnika s uznapredovalim rakom koji je zahvatio kost.
Other information about Zoledronic Acid Hospira
Ostale informacije o Zoledronatnoj kiselini Hospira
The reference medicine for the 4 mg/5 ml concentrate and 4 mg/100 ml solution is Zometa.
Referentni lijek za koncentrat od 4 mg/5 ml i otopinu od 4 mg/100 ml je Zometa.
Zoledronic Acid Hospira is a medicine that contains the active substance zoledronic acid.
Zoledronatna kiselina Hospira je lijek koji sadrži djelatnu tvar zoledronatnu kiselinu.
Zoledronic Acid Hospira zoledronic acid
Zoledronatna kiselina Hospira zoledronatna kiselina
Based on this plan, safety information has been included in the summary of product characteristics and the package leaflet for Zoledronic Acid Hospira, including the appropriate precautions to be followed by healthcare professionals and patients.
Zoledronatnu kiselinu Hospira uključene su sigurnosne informacije, uključujući odgovarajuće mjere opreza kojih se zdravstveni djelatnici i bolesnici trebaju pridržavati.
Why has Zoledronic Acid Hospira been approved?
Zašto je Zoledronatna kiselina Hospira odobrena?
Therefore, the CHMP's view was that, as for Zometa and Aclasta, the benefit outweighs the identified risks.
Stoga je stav CHMP-a kako koristi nadmašuju utvrđene rizike, kao i kod lijekova Zometa i Aclasta.
What is Zoledronic Acid Hospira?
Što je Zoledronatna kiselina Hospira?
How is Zoledronic Acid Hospira used?
Kako se Zoledronatna kiselina Hospira koristi?
How has Zoledronic Acid Hospira been studied?
Kako je Zoledronatna kiselina Hospira ispitivana?
What is Zoledronic Acid Hospira used for?
Za što se Zoledronatna kiselina Hospira koristi?
How does Zoledronic Acid Hospira work?
Kako djeluje Zoledronatna kiselina Hospira?
Date of first authorisation: 04/12/2013 Date of latest renewal: 24/09/2018
Datum prvog odobrenja: 04/12/2013 Datum produljenja odobrenja: 24/09/2018
Wash hands immediately after use.
Oprati ruke odmah nakon korištenja.
Do not smoke, drink or eat during application.
Ne pušiti, piti ili jesti za vrijeme primjene.
ATC vet code: QP54AA54.
ATC vet kod: QP54AA54
Overdose (symptoms):
Predoziranje (simptomi):
If this occurs, wash off with soap and water.
Ako se to dogodi, treba ih isprati sapunom i vodom.
Opened applicators should be disposed of immediately.
Otvorene aplikatore treba zbrinuti odmah.
Recently treated animals should not sleep with owners, especially children.
Nedavno liječene životinje ne smiju spavati s vlasnicima, osobito djecom.
Avoid contact with the cat's eyes.
Izbjegavajte kontakt s mačjim očima.
Therefore, epidemiological information about current susceptibility of the target species should be taken into account in order to limit the possibility of a future selection for resistance.
Epidemiološke podatke o trenutnoj osjetljivosti ciljnih vrsta treba uzeti u obzir kako bi se smanjila mogućnost pojave rezistencije u budućnosti.
Clear colourless to yellow to red/brown solution.
Bistra bezbojna do žuta do crveno/smeđa otopina.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
4.10 Predoziranje (klinički znakovi, hitni postupci, antidoti), ako je nužno
Correct application will minimise the occurrence of such events (see section 4.9).
Pravilna primjena će smanjiti pojavu takvih nuspojava (vidjeti odjeljak 4.9).
Do not use in rabbits.
Ne koristiti u kunića.
For the full list of excipients, see section 6.1.
Za popis pomoćnih tvari, vidjeti dio 6.1.
(S)-methoprene, once absorbed, is very quickly metabolised and excreted.
(S)-metopren, jednom apsorbiran se vrlo brzo metabolizira i eliminira.
Other animals living in the same household should also be treated with a suitable product.
Druge životinje koje žive u domaćinstvu treba također zaštiti odgovarajućim proizvodom.
Fipronil sulfone, as a photodegradation product of fipronil, is also found on the hair.
Fipronil sulfon, kao proizvod fotodegradacije fipronila se također nalazi na dlaci.
Children should not be allowed to play with treated animals during this period.
Djeci se ne smije dozvoliti da se igraju s tretiranim životinjama tijekom tog razdoblja.
No data on the effect of bathing/shampooing on the efficacy of the veterinary medicinal product in cats is available.
Nema raspoloživih podataka o utjecaju kupanja/šamponiranja na učinkovitost veterinarskomedicinskog proizvoda u mačaka.
Select the applicator size (or combination of applicators, for cats >7.5 kg) adapted to the cat's weight.
Odaberite veličinu aplikatora (ili kombinaciju aplikatora, za mačke > 7,5 kg), prilagođenu težini mačke.
Disintegrated and partially digested fragments may occasionally be seen in the faeces.
Raspadnuti i djelomično probavljeni dijelovi parazita se mogu povremeno vidjeti u izmetu.
Avoid contact of the applicator content with the fingers.
Izbjegavati dodir sadržaja aplikatora s prstima.
Applicator
Aplikator
On very rare occasions, symptomatic treatment can be required.
Vrlo rijetko može biti potrebno odgovarajuće simptomatsko liječenje.
Symptomatic treatment can be required if the signs do not resolve spontaneously within 24 hours.
Odgovarajuće simptomatsko liječenje može biti potrebno ako svi znakovi spontano ne prođu u roku od 24 sata.
The product should be applied to dry skin in an area where the cat cannot lick it off.
Ovaj proizvod treba primijeniti na suhu kožu, na mjesto s kojeg ga mačka ne može polizati.
Praziquantel has a moderate tissue distribution, and about 64-84% of praziquantel is bound to plasma proteins.
Prazikvantel ima umjerenu distribuciju u tkivu, oko 64-84% prazikvantela je vezano za proteine plazme.
However, brief contact of the animal with water on one or two occasions within the month following application is unlikely to significantly reduce its efficacy.
Međutim, kratkotrajni doticaj životinje s vodom, jednom ili dva puta unutar mjesec dana nakon primjene, neće bitno umanjiti učinkovitost.
The safety of the veterinary medicinal product has not been established during pregnancy and lactation.
Neškodljivost veterinarsko medicinskog proizvoda nije utvrđena tijekom graviditeta i laktacije.
Prevention of heartworm disease (Dirofilaria immitis larvae) should start within 1 month after the first expected exposure to mosquitoes.
Prevencija dirofilarioze (Dirofilaria immitis) treba početi unutar mjesec dana nakon prve očekivane izloženosti komarcima.
Echinococcosis represents a hazard for humans, and is a notifiable disease to the World Organisation for Animal Health (OIE).
Ehinokokoza predstavlja opasnost za ljude i prijavljuje se Svjetskoj organizaciji za zdravlje životinja (OIE).
If you notice any side effects, even those not already listed in this package leaflet or you think that the medicine has not worked, please inform your veterinary surgeon.
Ako zamijetite bilo koju nuspojavu, čak i one nuspojave koje nisu opisane u uputi o VMP ili ako mislite da proizvod nije djelovao, molimo obavijestite svog veterinara.
Place the tip of the applicator on the skin and apply the entire content directly onto the skin in one spot.
Postaviti vrh aplikatora na kožu i nanijeti cijeli sadržaj izravno na kožu na jednom mjestu.
Do not use in sick or convalescent animals.
Ne koristiti u bolesnih ili životinja u rekonvalescenciji.
Treatment should not be extrapolated from one animal to the other without veterinary opinion.
Režim primjene na jednoj životinji se ne smije koristi za druge životinje bez veterinarskog mišljenja.
(S)-Methoprene is an insect growth regulator (IGR) of the class of compounds known as juvenile hormone analogues that inhibit the development of immature stages of insects.
(S)-metopren je regulator rasta kukaca (IGR) iz skupine spojeva poznatih kao analozi juvenilnog hormona koji inhibiraju razvoj nezrelih stadija kukaca.
Do not use this veterinary medicinal product after the expiry date which is stated on the carton after EXP.
Ne koristiti veterinarsko-medicinski proizvod poslije isteka roka valjanosti naznačenog na kutiji poslije EXP.
Any unused veterinary medicinal product or waste material derived from it should be disposed of in accordance with local requirements.
Bilo koji neupotrebljeni veterinarsko-medicinski proizvod ili otpadni materijali dobiven primjenom tih veterinarsko-medicinskih proizvoda treba se odlagati u skladu s lokalnim propisima.
Its metabolism is limited, and it is mainly excreted unchanged in the faeces.
Metabolizam mu je ograničen, te se uglavnom eliminira nepromijenjen u izmetu.
In long hair breeds, special attention should be paid to apply the product onto the skin, and not on the hair to ensure optimal efficacy.
dugodlakih pasmina, posebnu pozornost treba posvetiti primjeni proizvoda na kožu, a ne na dlaku čime se osiguravala optimalna učinkovitost.
4 Chemin du Calquet, 31000 Toulouse
4 Chemin du Calquet, 31000 Toulouse FANCUSKA
BROADLINE or empty container should not enter water courses as this may be dangerous for fish and other aquatic organisms.
BROADLINE ili prazna ambalaža ne smije se odlagati u vodotokove zbog opasnosti za ribe i druge vodene organizme.
Pharmacotherapeutic group: antiparasitic products, insecticides, avermectins, eprinomectin in combinations.
Farmakoterapijska skupina: antiparazitici, insekticidi, avermektini, eprinomektin u kombinaciji.
Once absorbed, eprinomectin is highly bound to plasma proteins (> 99%), has low clearance from blood, and distributes well into tissues.
Nakon što se absorbira, eprinomektin se čvrsto veže za proteine plazme (> 99%), teško se eliminira iz krvi te izvrsno distribuira u tkivima.
Eprinomectin and praziquantel act systemically, with plasma concentrations reaching a maximum within 48 hours and 6 hours after treatment, respectively, reaching mean maximum concentrations (Cmax) of 20.1 ng/ml for eprinomectin and 157 ng/ml for praziquantel.
Eprinomektin i prazikvantel djeluju sustavno uz maksimalnu koncentraciju u plazmi u roku od 48 sati i 6 sati nakon tretmana, odnosno postizanja maksimalne koncentracije (Cmax) od 20,1 ng/ml za eprinomektin i 157 ng/ml za prazikvantel.
Glycerol formal Disodium edetate (E385) Propyl gallate (E310) Thiodipropionic acid Dimethyl isosorbide Butylhydroxytoluene (E321)
Glicerol formal Dinatrijev edetat (E385) Propil galat (E310) Tiodipropionska kiselina Dimetil izosorbid Butilhidroksitoluen (E321)
This compound mimics the action of juvenile hormone and causes impaired development and death of the developing stages of fleas.
Ovaj spoj oponaša djelovanje juvenilnog hormona i uzrokuje nepravilan razvoj i smrt razvojnih faza buha.
The peak plasma concentrations of the absorbed fraction of fipronil and (S)-methoprene are reached within 8 to 9 hours.
Vrhunac koncentracije u plazmi apsorbiranog fipronila i (S)-metoprena postiže se unutar 8 do 9 sati.
In case of accidental eye exposure, flush the eyes thoroughly with water as the product can cause slight mucous membrane and eye irritation.
slučaju dodira s očima, vodom temeljito isprati oči s obzirom da proizvod može izazvati blagu iritaciju sluznice i oka.
Do not inject, do not administer orally or via any other route.
Nemojte ubrizgavati, niti davati na usta ili na bilo koji drugi način.
The rationale for prescription should be tailored to the individual needs of the cat, based on clinical assessment, the animal's lifestyle and on the local epidemiological situation (including zoonotic risks, where relevant) in order to address exclusively situations of mixed infestations/risk of infestation.
Odluku o propisivanju treba uskladiti s individualnim potrebama mačke, temeljenu na kliničkoj slici, načinu života i lokalnoj epidemiološkoj situaciji (uključujući zoonotski rizik, ukoliko je bitno) isključivo u cilju rješavanja mješovitih infestacija/rizika od infestacija.
Remove the applicator from the package and hold it upright.
- Ukloniti aplikator iz pakovanja i držati ga uspravno.
However, as a precaution, it is not recommended to bath animals within 2 days after treatment.
Međutim, kao mjera predostrožnosti, nije preporučljivo kupati životinje unutar 2 dana nakon aplikacije.
Cats in areas endemic for heartworm, or those which have travelled to endemic areas, may be infected with adult heartworms.
Mačke u endemskim područjima s dirofilariozom, ili one koje su putovale u endemska područja, mogu biti invadirane odraslim dirofilarijima.
The veterinary medicinal product is not intended for use in dogs.
Veterinarsko medicinski proizvod nije namijenjen psima.
In vitro metabolism assays and in vivo studies have demonstrated that there are no pharmacodynamic or pharmacokinetic interactions between fipronil, (S)-methoprene, eprinomectin and praziquantel.
In vitro testovi metabolizma i in vivo studije su pokazale da ne postoji farmakodinamička ili farmakokinetička interakcija između fipronila, (S)-metoprena, eprinomektina i prazikvantela.
Correct application will minimise the occurrence of such events (see section DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION).
Pravilna primjena će smanjiti pojavu takvih nuspojava (vidjeti odjeljak Doziranje za svaku ciljnu vrstu životinja, način i put primjene).
Unlike other species, fipronil sulfone is not formed in cat.
fipronil sulfon se u mački ne stvara.
In these severe cases concomitant treatment may be necessary.
U takvim ozbiljnim slučajevima dodatno liječenje može biti potrebno.
After treatment with BROADLINE, ticks will generally be killed within 48 hours after infestation without having a blood meal.
Nakon tretmana s BROADLINE-om, krpelji će uglavnom uginuti u roku od 48 sati nakon infestacije, bez konzumiranja krvnog obroka.
Unit dose syringe-shaped applicators (clear siliconised cyclic olefin copolymer (COC)) containing 0.3 ml or 0.9 ml of product, closed with a polymer cap and placed in individual plastic blisters.
Jedinične doze aplikatora u obliku brizgalice (od čistog silikoniziranog cikličkog olefinskog kopolimera (HOO)) zatvorene s kapom polimera, koji sadrže 0,3 ml ili 0,9 ml proizvoda i smještene u pojedinačnim plastičnim blisterima.
Wear gloves when handling the veterinary medicinal product.
Nositi rukavice tijekom primjene veterinarsko-medicinskog proizvoda.
Praziquantel is a synthetic isoquinoline-pyrazine derivative with activity against tapeworms.
Prazikvantel je sintetički izokinolin-pirazinski derivat s aktivnošću protiv crijevnih trakavica.
- Prevention of environmental flea contamination by inhibiting the development of flea immature stages (eggs, larvae and pupae) for over a month.
- Prevencija kontaminacije okoliša buhama inhibicijom razvoja nezrelih stadija buha (jaja, ličinki i kukuljica) tijekom razdoblja dužeg od mjesec dana.
This results in severe damage to the parasite integument, contraction and paralysis, disruption of metabolism and finally leads to the death and expulsion of the parasite.
Isto rezultira teškim oštećenjem stjenke parazita, kontrakcije i paralize, poremećaja metabolizma i na kraju uginućem parazita i njegovog izbacivanja.
Brief contact of the animal with water within the month following application is unlikely to reduce the efficacy of the product.
Kratkotrajni doticaj životinje s vodom tijekom mjesec dana od primjene neće utjecati na učinkovitost proizvoda.
- Treatment and prevention of infestations by ticks (Ixodes ricinus).
- Liječenje i prevencija infestacije krpeljima (Ixodes ricinus).
It is important to apply the veterinary medicinal product to a skin area where the cat cannot lick it off: on the neck, in between shoulders.
Ovaj veterinarsko-medicinski proizvod bitno je primijeniti na kožu, na mjestu s kojeg ga mačka ne može polizati: na vratu i između lopatica.
The ectoparasitic activity of fipronil and (S)-methoprene is mediated by direct contact with the ectoparasites rather than by systemic exposure.
Ektoparaziticidno djelovanje fipronila i (S)-metoprena posljedica je izravnog dodira s ektoparazitima, a ne sustavne izloženosti.
The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s)) - common (more than 1 but less than 10 animals in 100 animals treated) - uncommon (more than 1 but less than 10 animals in 1,000 animals treated) - rare (more than 1 but less than 10 animals in 10,000 animals treated) - very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
- rijetke (više od 1, ali manje od 10 životinja na 10.000 tretiranih životinja) - vrlo rijetke (manje od 1 životinje na 10.000 tretiranih životinja, uključujući izolirane slučajeve).
If eye irritation persists or if side effects are noted, seek medical advice and show the package leaflet or the label to the physician.
Ako nadraženost oka ne prestane ili ako se pojave nuspojave, treba potražiti savjet liječnika i pokazati mu uputu ili etiketu.
The topical application, with additional potential oral exposure from grooming, also results in partial systemic exposure that decreases over time.
Lokalna primjena s dodatnom mogućom izloženošću preko usta (lizanje), dovodi do djelomične sustavne izloženosti koja se smanjuje tijekom vremena.
Use the applicator size adapted to the weight of the cat.
Koristiti aplikator veličine prilagođene težini mačke.
Pull back the plunger slightly, twist and pull off the cap.
Povući klip malo unazad, okrenuti i maknuti poklopac.