natgillin/translations-raw huggingface dataset:
In more than half of the reported cases, treatment with protease inhibitors was continued, or reintroduced if treatment had been discontinued.
U više od polovine prijavljenih slučajeva nastavljeno je liječenje inhibitorima proteaze ili je nakon prekida ponovno uvedeno.
Don't take a double dose to make up for a missed dose.
Nemojte uzeti dvostruku dozu kako biste nadoknadili zaboravljenu dozu.
However, only 65 % of patients were receiving a PI based regimen at study entry.
Međutim, samo je 65% bolesnika, pri uključivanju u ispitivanje, bilo na režimu temeljenom na PI.
• Tingling or numbness around the lips and mouth.
• trnci ili utrnulost oko usana i usta.
See section ‘Other medicines and Telzir'.
Vidjeti dio "Drugi lijekovi i Telzir".
In some patients administration of factor VIII was necessary.
Kod nekih je bolesnika bilo potrebno primijeniti faktor VIII.
Results through 48 weeks of treatment are provided below.
Rezultati tijekom 48 tjedana liječenja navedeni su u nastavku.
What Telzir looks like and contents of the pack
Kako Telzir izgleda i sadržaj pakiranja
This change will decrease the total active substance concentration in the plasma, however the amount of unbound amprenavir, which is the active moiety, is likely to be unchanged.
Ta promjena smanjit će ukupnu koncentraciju djelatne tvari u plazmi, međutim, količina nevezanog amprenavira, koja predstavlja funkcionalnu grupu, vjerojatno će ostati nepromijenjena.
If you have any further questions about ritonavir or the other medicines prescribed, please ask your doctor or pharmacist.
Ako imate dodatnih pitanja o ritonaviru ili drugim lijekovima koji su Vam propisani, molimo obratite se svom liječniku ili ljekarniku.
Patients aged 6 to 11 N=30
Bolesnici u dobi od 6 do 11 godina N=30
CCR5-receptor antagonists
Antagonisti receptora CCR5
Hertfordshire SG12 0DJ United Kingdom
Hertfordshire SG12 0DJ Ujedinjeno Kraljevstvo
The importance of complying with the full recommended dosing regimen should be stressed to all patients.
Svim bolesnicima treba naglasiti važnost pridržavanja cijelog preporučenog režima doziranja.
Patients aged 12 to 18 N=40
Bolesnici u dobi od 12 do 18 godina N=40
ITT-E Population TLOVR analysis
ITT-E Populacija TLOVR analiza
No comparative studies have been undertaken in children or adolescents.
Komparativna ispitivanja nisu se provodila na djeci i adolescentima.
On rare occasions, these muscle disorders have been serious (rhabdomyolysis).
U rijetkim slučajevima su te poteškoće s mišićima bile ozbiljne (rabdomioliza).
Following completion of the 48 week treatment period, subjects at European and Canadian sites were eligible to participate in a study extension to Week 144 maintaining their treatment regimen as per the original randomisation.
Nakon završetka razdoblja liječenja od 48 tjedana, ispitanici u Europi i Kanadi mogli su sudjelovati u nastavku ispitivanja do 144. tjedna održavajući svoj režim liječenja kako su randomizirani na početku ispitivanja.
You may have problems with your bones
Možda ćete imati tegoba s kostima
• if their immune systems are very weak
• koji imaju vrlo slab imunološki sustav
Following administration of Telzir, the half-life of amprenavir is 7.7 hours.
Nakon primjene lijeka Telzir poluvrijeme amprenavira je 7,7 sati.
All Patients CD4-count <50
Svi bolesnici Broj CD4 <50
Resistance patterns were similar to those observed in adults.
Obrasci rezistencije bili su sliči onima primijećenima u odraslih.
• Flare up of old infections
• Razbuktavanje starih infekcija
• if you are taking any of these medicines:
• ako uzimate neki od sljedećih lijekova:
NEUROLEPTIC Pimozide
NEUROLEPTICI Pimozid
If you notice any symptoms of infection or other symptoms such as muscle weakness, weakness beginning in the hands and feet and moving up towards the trunk of the body, palpitations, tremor or hyperactivity, please inform your doctor immediately to seek necessary treatment.
Ako primijetite bilo koji simptom infekcije ili druge simptome poput slabosti mišića, slabosti koja počinje u šakama i stopalima i širi se prema trupu, osjećaja lupanja srca, nevoljnog drhtanja ili hiperaktivnosti, molimo odmah se obratite liječniku kako biste primili potrebno liječenje.
HIV can become resistant to anti-HIV medicines.
HIV može postati otporan na lijekove protiv HIV-a.
Put the syringe into your mouth, placing the tip of the syringe against the inside of your cheek.
Stavite štrcaljku u usta, smještajući vrh štrcaljke uz unutarnju stranu obraza.
• Increase in cholesterol (a type of blood fat).
• povećanje razine kolesterola (vrsta masnoća u krvi).
The efficacy and safety of these therapies with fosamprenavir and ritonavir has not been established.
Nije utvrđena djelotvornost i sigurnost tih terapija s fosamprenavirom i ritonavirom.
Your dose of Telzir may need to be changed if you are taking • etravirine (used to treat HIV infection)
Vašu dozu lijeka Telzir možda će trebati promijeniti ako uzimate • etravirin (koristi se za liječenje HIV infekcije)
In in vitro studies, the protein binding of amprenavir is approximately 90 %.
U ispitivanjima in vitro vezivanje proteina amprenavira je oko 90 %.
Also, some people have become diabetic while taking these medicines.
Nadalje, kod nekih osoba dijabetes se pojavio tijekom uzimanja ovih lijekova.
Amprenavir is a competitive inhibitor of the HIV-1 protease.
Amprenavir je kompetitivni inhibitor HIV-1 proteaze.
Protease is an enzyme produced by HIV which enables the virus to multiply in white blood cells (CD4 cells) in your blood.
Proteaza je enzim kojeg stvara HIV virus, a koji omogućava umnožavanje virusa u bijelim krvnim stanicama (CD4 stanicama) u Vašoj krvi.
According to current treatment guidelines, dual therapy with protease inhibitors is generally not recommended.
U skladu s trenutnim terapijskim smjernicama općenito se ne preporučuje dvojna terapija inhibitorima proteaze.
INHALED/NASAL STEROIDS
INHALACIJSKI/NAZALNI STEROIDI
As an alternative to taking Telzir oral suspension:
Kao alternativa za Telzir oralnu suspenziju:
Caution is warranted and close monitoring is recommended when this combination is given in integrase inhibitorresistant patients.
Potreban je oprez i preporučuje se pomno praćenje kada se ta kombinacija daje bolesnicima rezistentnim na inhibitor integraze.
However, the bioequivalence could not be demonstrated when the oral suspension was given with food.
Bioraspoloživost se, međutim, nije mogla utvrditi pri davanju oralne suspenzije s hranom.
The decrease in amprenavir AUC can result in virological failure and resistance development.
Smanjenje AUC amprenavira može dovesti do neuspješnog virološkog djelovanja i razvoja otpornosti.
• if they are also taking anti-inflammatory medicines called corticosteroids
• koji su uzimali i protuupalne lijekove koje nazivano kortikosteroidima
Glaxo Wellcome Operations, Priory Street, Ware, Hertfordshire SG12 0DJ, United Kingdom Glaxo Wellcome S.A., Avenida de Extremadura 3, 09400 Aranda de Duero Burgos, Spain Oral suspension
Glaxo Wellcome Operations, Priory Street, Ware, Hertfordshire SG12 0DJ, Ujedinjeno Kraljevstvo Glaxo Wellcome S.A., Avenida de Extremadura 3, 09400 Aranda de Duero Burgos, Španjolska Oralna suspenzija
Week 48 AAUCMB (n)
AAUCMB u 48. tjednu (n)
• if they have been taking combination therapy for a long time
• koji su uzimali kombiniranu terapiju tijekom dugog vremenskog razdoblja
Medicinal products - interactions
Lijekovi - interakcije
Frequency categories for the reactions below have been based on clinical trials and postmarketing data.
Kategorije učestalosti za reakcije navedene u nastavku temelje se na kliničkim ispitivanjima i postmarketinškim podacima.
Patients should be advised to seek medical advice if they experience joint aches and pain, joint stiffness or difficulty in movement.
Bolesnike treba savjetovati da zatraže medicinsku pomoć ako osjete bolove u zglobovima, ukočenost zglobova ili poteškoće pri kretanju.
ITT (Ext) Population TLOVR analysis
ITT (Ext) Populacija TLOVR analiza
Metabolites account for approximately 14 % of the administered amprenavir dose in the urine, and approximately 75 % in the faeces.
Metaboliti predstavljaju oko 14% primijenjene doze amprenavira u urinu i oko 75% u fecesu.
• If you have a known allergy to medicines containing sulphonamide.
• Imate li poznate alergije na lijekove koji sadrže sulfonamide.
Median (n)
Medijan (n)
Telzir is used to treat HIV (human immunodeficiency virus) infection.
Telzir se koristi za liječenje HIV (humani virus imunodeficijencije) infekcije.
It should be noted that the Telzir oral suspension has not been evaluated clinically in adults and that the adverse reaction profile detailed in this section is based on the experience in adults with the Telzir film coated tablets.
Potrebno je napomenuti sa se Telzir oralna suspenzija nije klinički procjenjivala u odraslih osoba te da se profil nuspojava koji se detaljno navodi u ovom dijelu temelji na iskustvima odraslih osoba s Telzir filmom obloženim tabletama.
This is based on safety data from a total of 864 patients exposed to fosamprenavir/ritonavir in these three studies.
To se temelji na podacima o sigurnosti dobivenim od 864 bolesnika koji su u bili izloženi fosamprenaviru/ritonaviru u navedena 3 ispitivanja.
Glaxo Operations UK Ltd (trading as GlaxoWellcome Operations)
Glaxo Operations UK Ltd (posluje kao GlaxoWellcome Operations)
Severe and life-threatening skin reactions, including Stevens-Johnson syndrome, were reported in less than 1% of patients included in the clinical development programme.
Teške kožne reakcije opasne po život, uključujući Stevens-Johnsonov sindrom prijavljene su u manje od 1% bolesnika uključenih u klinički razvojni program.
Conclusions regarding the relevance of particular mutations or mutational patterns are subject to change with additional data, and it is recommended to always consult current interpretation systems for analysing resistance test results.
Zaključci o značaju određenih mutacija ili mutacijskih obrazaca podložni su promjenama u skladu s dodatnim podacima te se za analizu rezultata ispitivanja rezistencije preporučuje konzultirati trenutno važeći interpretacijski sistem.
ITT-E observed analysis
Opažena ITT-E analiza
Significant ↓ APV expected
Očekuje se značajno ↓ APV
• Increases in enzymes produced by the liver called transaminases, increases of an enzyme produced by the pancreas called lipase.
• povećanje enzima koje stvara jetra, a koji se nazivaju transaminaze, povećanje enzima koje stvara gušterača a koji se nazivaju lipaze.
With this condition, parts of the bone tissue die because of reduced blood supply to the bone.
U tom stanju, dijelovi koštanog tkiva odumiru zbog smanjene opskrbe krvi u kostima.
Aspen Bad Oldesloe GmbH, Industriestrasse 32-36, D-23843, Bad Oldesloe, Germany or
Aspen Bad Oldesloe GmbH, Industriestrasse 32-36, D-23843, Bad Oldesloe, Njemačka ili
This dose adjustment cannot be made with Telzir tablets.
Tu prilagodbu doze nije moguće učiniti s Telzir tabletama.
When Telzir is co-administered with ritonavir, the half-life of amprenavir is increased to 15 - 23 hours.
Kada se Telzir istodobno primjenjuje s ritonavirom poluvrijeme amprenavira povećava se na 15-23 sata.
Study performed with amprenavir.
Ispitivanje je provedeno s amprenavirom.
Etravirine Cmin↔a Etravirine Cmax↔a a Comparison based on historic control.
Etravirin AUC ↔a Etravirin Cmin↔a Etravirin Cmax↔a a Usporedba temeljena na povijesnoj kontroli.
You may experience muscle problems
Možete imati tegobe s mišićima
Hormonal contraception
Hormonska kontracepcija
The mean AAUCMBs (log10 c/ml) in the ITT (E) population (Observed analysis) at 48 weeks (primary end-point) and other efficacy outcomes by subgroup are described in the tables below:
Srednja vrijednost AAUCMB (log10 c/ml) u ITT (E) populaciji (opažena analiza) u 48. tjednu (primarni ishod) i drugi ishodi djelotvornosti prema podskupinama opisuju se u tablicama koje slijede:
Greater effects may be expected when fluticasone propionate is inhaled.
Mogu se očekivati snažniji učinci pri inhalaciji flutikazon propionata.
If you notice any muscle problems: →Tell your doctor.
Ako primijetite bilo kakav problem s mišićima: →Obavijestite svog liječnika.
You may get a skin rash.
Možda će se kod Vas razviti kožni osip.
Telzir does not require any special storage conditions.
Telzir ne zahtijeva posebne uvjete čuvanja.
• clarithromycin, erythromycin (an antibiotic)
• klaritromicin, eritromicin (antibiotik)
Some people taking combination therapy for HIV develop a condition called osteonecrosis.
Kod nekih ljudi koji uzimaju kombinirani terapiju za HIV može se razviti stanje koje nazivamo osteonekroza.
Adults with liver disease
Odrasli s bolešću jetre
Therapy should be initiated by a physician experienced in the management of HIV infection.
Terapiju treba započeti liječnik koji je iskusan u liječenju HIV infekcija.
In view of the low exposure in reproductive toxicity studies, the potential developmental toxicity of Telzir has not been fully determined.
U pogledu niske izloženosti tijekom ispitivanja reproduktivne toksičnosti, potencijalna razvojna toksičnost lijeka Telzir nije u cijelosti utvrđena.
Aspartate aminotransferase increased
Povećana razina aspartat aminotransferaze
It is not known whether amprenavir can be removed by peritoneal dialysis or haemodialysis.
Nije poznato može li se amprenavir ukloniti peritonealnom dijalizom ili hemodijalizom.
A reduction in the rifabutin dosage by at least 75 % is recommended when administered with Telzir with ritonavir.
Preporučuje se smanjenje doze rifabutina za barem 75% kada ga se primjenjuje s lijekom Telzir i s ritonavirom.
Telzir is a type of medicine known as an anti-retroviral.
Telzir je vrsta lijeka poznata kao antiretrovirusni lijek.
150 mg every other day
150 mg svaki drugi dan
The dose recommendations for this population therefore take into account the observed food effect (see section 4.2).
Preporuke doziranja za ovu populaciju uzimaju u obzir zamijećene utjecaje hrane (vidjeti dio 4.2).
(Ritonavir 100 mg capsules twice daily for 7 days)
(Ritonavir 100 mg kapsule 2 puta dnevno tijekom 7 dana)
Increased bleeding may occur while taking protease inhibitors (such as Telzir).
Može doći do povećanih krvarenja tijekom uzimanja inhibitora proteaze (poput lijeka Telzir).
Doses of atorvastatin no greater than 20 mg/day should be administered, with careful monitoring for atorvastatin toxicity.
Treba primijeniti doze atorvastatina koje nisu veće od 20 mg/dan uz pažljivo praćenje toksičnosti atorvastatina.
Potential for increased alfuzosin concentrations which can result in hypotension.
Postoji potencijal za povećanje koncentracije alfuzosina što može dovesti do hipotenzije.
The pharmacokinetics of fosamprenavir in combination with ritonavir has not been studied in patients over 65 years of age.
Farmakokinetika fosamprenavira u kombinaciji s ritonavirom nije ispitana kod bolesnika starijih od 65 godina.
• The active substance is fosamprenavir.
• Djelatna tvar je fosamprenavir.
< 4 mutations from score
< 4 mutacije od ocjene
Taking Telzir and ritonavir while taking the contraceptive pill may harm your liver and may stop the contraceptive from working properly.
Uzimanje lijeka Telzir i ritonavira dok uzimate kontracepcijske pilule može oštetiti Vašu jetru i spriječiti odgovarajuće djelovanje kontraceptiva.
Week 96 Week 144
96. tjedan 144. tjedan
In females, at the high dose, there was a reduction in the weight of gravid uterus (0 to 16%) probably due to a reduction of the number of ovarian corporea lutea and implantations.
Kod ženki je pri visokim dozama došlo do smanjenja težine gravidnih uterusa (0-16%), najvjerojatnije zbog smanjenja broja žutih tijela u ovarijima i broja implantacija.
Telzir belongs to a group of anti-retroviral medicines called protease inhibitors.
Telzir pripada skupini antiretrovirusnih lijekova koje nazivamo inhibitori proteaze.
Capsule or Solution 100 mg
Kapsule ili otopina 100 mg
Co-administration of amprenavir with grapefruit juice was not associated with clinically significant changes in plasma amprenavir pharmacokinetics.
Istodobna primjena amprenavira sa sokom od grejpa nije bila povezana s klinički značajnim promjenama farmakokinetike amprenavira u plazmi.
If there is evidence of worsening liver disease in such patients, interruption or discontinuation of treatment must be considered.
Ako postoje dokazi da se kod tih bolesnika bolest jetre pogoršava, mora se razmotriti mogućnost privremenog ili trajnog prekida liječenja.
In case of withdrawal of glucocorticoids, progressive dose reduction may have to be performed over a longer period (see section 4.4).
U slučaju da se prestaje s korištenjem glukokortikoida, progresivno postupno smanjenje doze možda treba provesti kroz duže vremensko razdoblje (vidjeti dio 4.4).
AAUCMB Observed Analysis
AAUCMB analiza opaženog
The decrease of (R-) methadone (active enantiomer) is not expected to be clinically significant.
Ne očekuje se klinički značajno smanjenje (R-) metadona (aktivnog enantiomera).
The relationship between in vitro anti-HIV-1 activity of amprenavir and the inhibition of HIV-1 replication in humans has not been defined.
Nije definiran odnos između in vitro anti-HIV-1 aktivnosti amprenavira i inhibicije HIV-1 replikacije kod ljudi.
If you forget to take Telzir
Ako ste zaboravili uzeti Telzir
Ritonavir induces CYP3A4, CYP1A2, CYP2C9 and glucuronosyl transferase.
Ritonavir inducira CYP3A4, CYP1A2, CYP2C9 i glukuronozil transferazu.
When treating HIV, it can be hard to tell whether side effects are caused by Telzir, by other medicines taken at the same time or by the HIV disease itself.
Kod liječenja HIV-a, ponekad može biti teško utvrditi da li su nuspojave uzrokovane lijekom Telzir, drugim lijekovima koje istodobno uzimate ili samom HIV bolesti.
Midazolam: ↑ expected (3-4 fold for parenteral midazolam)
Midazolam: očekuje se ↑ (3-4 puta pri parenteralnoj primjeni midazolama)
Any inflammatory symptoms should be evaluated and treatment instituted when necessary.
Sve simptome upale mora se procijeniti i prema potrebi započeti liječiti.
Other medicines and Telzir
Drugi lijekovi i Telzir
Potential for serious and/or life-threatening reactions such as acute ergot toxicity characterized by peripheral vasospasm and ischemia of the extremities and other tissues.
Postoji potencijal za ozbiljne i/ili po život opasne reakcije kao što je akutna ergot toksičnosti koju karakterizira periferni vazospazam i ishemija ekstremiteta i drugih tkiva.
There have been reports of muscle pain, tenderness or weakness, particularly with antiretroviral therapy including protease inhibitors and nucleoside analogues.
Bilo je prijava boli u mišićima, osjetljivosti ili slabosti, pogotovo s antiretrovirusnom terapijom koja uključuje inhibitore proteaze i analoge nukleozida.
Fosamprenavir AUC values are, in general, less than 1 % of those observed for amprenavir.
Vrijednosti AUC za fosamprenavir općenito su manje od 1% zabilježenih za amprenavir.
Pharmacotherapeutic group: Antivirals for systemic use, protease inhibitor, ATC Code: J05AE07 Mechanism of action
Farmakoterapijska skupina: Antivirusni lijekovi za sistemsku primjenu, inhibitori proteaze, ATK oznaka: J05AE07
FPV/RTV BID - Fosamprenavir with ritonavir twice daily, LPV/RTV BID - Lopinavir / ritonavir twice daily
FPV/RTV BID - Fosamprenavir s ritonavirom 2 puta dnevno, LPV/RTV BID - Lopinavir/ritonavir 2 puta dnevno
• Problems with your bones.
• Tegobe s kostima.
No dosing recommendations can be made for the very young (children < 2 years of age) and Telzir with ritonavir is not recommended for this patient population (see section 4.2).
Ne mogu se donijeti preporuke o doziranju za jako mladu djecu (djeca u dobi < 2 godine starosti) te se Telzir s ritonavirom ne preporučuje za tu populaciju bolesnika (vidjeti dio 4.2).
Single 30 ml dose of antacid suspension (equivalent to 3.6 grams aluminium hydroxide and 1.8 grams magnesium hydroxide
Jedna doza od 30 ml suspenzije antacida (ekvivalent 3,6 g aluminijhidroksida i 1,8 g magnezijhidroksida
ANTIHISTAMINES (HISTAMINE H1 RECEPTOR ANTAGONISTS) Astemizole Terfenadine
ANTIHISTAMINICI (ANTAGONISTI HISTAMINSKIH H1 RECEPTORA) Astemizol
Resistance testing diagnostic companies have developed clinical phenotypic cut-offs for FPV/RTV that can be used to interpret resistance test results.
Dijagnostičke tvrtke za ispitivanje rezistencije razvile su fenotipske skale isključenja za FPV/RTV koje se mogu koristiti za interpretaciju rezultata testiranja rezistencije.
Stevens Johnson syndrome
Stevens-Johnsonov sindrom Angioedem
Therefore, any medicinal products that either share this metabolic pathway or modify CYP3A4 activity may modify the pharmacokinetics of amprenavir and ritonavir.
Stoga, bilo koji lijek koji također ima taj metabolički put ili modificira aktivnost CYP3A4, može modificirati farmakokinetiku amprenavira i ritonavira.
Osteonecrosis: cases of osteonecrosis have been reported, particularly in patients with generally acknowledged risk factors, advanced HIV disease or long-term exposure to CART.
Osteonekroza: prijavljeni su slučajevi osteonekroze, osobito kod bolesnika s opće poznatim faktorima rizika, uznapredovalom HIV bolešću ili dugotrajnom izloženošću CART-u.
Both of these studies compared fosamprenavir/ritonavir with lopinavir / ritonavir.
Oba ova ispitivanja uspoređivala su kombinacije fosamprenavira/ritonavira s lopinavirom/ritonavirom.
Telzir is supplied in plastic bottles containing 225 ml oral suspension.
Telzir dolazi u plastičnim bocama koje sadrže 225 ml oralne suspenzije.
PDE5 INHIBITORS Sildenafil
INHIBITORI PDE5 Sildenafil
Fosamprenavir is converted in man to amprenavir.
Fosamprenavir se kod ljudi pretvara u amprenavir.
It is taken with low doses of another medicine, ritonavir, which boosts the level of Telzir in the blood.
Uzima se s malom dozom drugog lijeka, ritonavira, koji podiže razine lijeka Telzir u krvi.
It can be treated with antihistamines.
Osip se može liječiti antihistaminicima.
Due to CYP3A inhibition by Telzir, concentrations of quetiapine are expected to increase.
Budući da Telzir inhibira CYP3A, očekuje se povećanje koncentracija kvetiapina.
The MAH shall perform the required pharmacovigilance activities and interventions detailed in the agreed RMP presented in Module 1.8.2 of the Marketing Authorisation and any agreed subsequent updates of the RMP.
Nositelj odobrenja obavljat će zadane farmakovigilancijske aktivnosti i intervencije detaljno objašnjene u dogovorenom Planu upravljanja rizikom (RMP), koji se nalazi u Modulu 1.8.2 Odobrenja za stavljanje lijeka u promet te svim sljedećim dogovorenim ažuriranim verzijama RMP-a.
Fosamprenavir is a pro-drug of amprenavir and must not be administered concomitantly with other medicinal products containing amprenavir.
Fosamprenavir je predlijek amprenavira i ne smije se primjenjivati istodobno s drugim lijekovima koji sadrže amprenavir.
If your liver disease gets worse, you may need to stop taking Telzir for a while, or permanently.
Ako dođe do pogoršanja bolseti jetre, možda ćete privremeno ili trajno morati prestati uzimati Telzir.
Shake the bottle vigorously for 20 seconds before first dose is removed and 5 seconds before each subsequent dose.
Prije uzimanja prve doze bocu snažno tresite 20 sekundi, a prije uzimanja svake sljedeće doze 5 sekundi.
The pharmacokinetics of fosamprenavir have not been studied in this patient population (see section 5.2).
Farmakokinetika fosamprenavira nije ispitivana u ovoj populaciji bolesnika (vidjeti dio 5.2).
ERGOT DERIVATIVES
ERGOT DERIVATI
Concomitant use is not recommended unless the potential benefit of treatment outweighs the risk of systemic corticosteroid effects (see section 4.4).
Istodobna primjena se ne preporučuje ukoliko potencijalna korist liječenja nije veća od rizika sistemskih učinaka kortikosteroida (vidjeti dio 4.4).
Take special care with Telzir Talk to your doctor or pharmacist before taking Telzir:
Obratite se svom liječniku ili ljekarniku prije nego uzmete Telzir:
The population enrolled mainly consisted of moderately antiretroviral experienced patients.
Populacija je uglavnom uključivala bolesnike s umjerenim iskustvom s antiretrovirusnim lijekovima.
These include:
Ta stanja uključuju: