natgillin/translations-raw huggingface dataset:
• Your child should not take Diacomit after the expiry date, which is stated on the label.
• Vaše dijete ne smije uzimati Diacomit nakon isteka roka valjanosti, navedenog na pakiranju.
Undesirable combinations (to be avoided unless strictly necessary) - Rye ergot alkaloids (ergotamine, dihydroergotamine) Ergotism with possibility of necrosis of the extremities (inhibition of hepatic elimination of rye ergot).
Nepoželjne kombinacije ( izbjegavati ukoliko nije strogo neophodno) - Alkaloidi ražene glavice (ergotamin, dihidroergotamin) Ergotizam s mogućnosti nekroze udova (inhibicija hepatičke eliminacije alkaloida ražene glavice)
Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system listed in Appendix V.
Od zdravstvenih radnika se traži da prijave svaku sumnju na nuspojavu lijeka putem nacionalnog sustava prijave nuspojava navedenog u Dodatku V*.
The consequences are increased plasma levels of these anticonvulsants with potential risk of overdose.
Posljedica je povećanje razine ovih antikonvulziva u plazmi s mogućim rizikom od predoziranja.
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Ako vam je liječnik rekao da ne podnosite neke šećere, obratite se liječniku prije uzimanja ovog lijeka.
Bottles of 30, 60 and 90 capsules in cardboard cartons.
Bočice od 30, 60 i 90 kapsula u kartonskim kutijama.
Likewise, the effect of stiripentol on their metabolism is not known.
Shodno tomu, nepoznat je utjecaj stiripentola na metabolizam ovih lijekova.
Aggressiveness, irritability, behaviour disorders, opposing behaviour, hyperexcitability, sleep disorders
Agresivnost, razdražljivost, poremećaji ponašanja, suprotstavljanje, hiperekscitabilnost, poremećaji sna
In the pivotal studies, when the use of stiripentol was initiated, the daily dose of clobazam was 0.5 mg/kg/day usually administered in divided doses, twice daily.
U ključnim ispitivanjima, kada je započeta primjena stiripentola, dnevna doza klobazama je bila 0,5 mg/kg/dan, obično podijeljena za primjenu dva puta na dan.
- Topiramate
- Topiramat
such as anorexia, loss of appetite, vomiting, your child's growth rate should be carefully monitored.
kao što su anoreksija, gubitak teka, povraćanje, potrebno je pažljivo nadzirati rast Vašeg djeteta.
In the absence of human studies on excretion in breast milk, and given that stiripentol passes freely from plasma into milk in the goat, breast-feeding is not recommended during treatment.
U odsustvu ispitivanja izlučivanja u majčino mlijeko u ljudi, a znajući da stiripentol prolazi slobodno iz plazme u mlijeko u koza, dojenje se ne savjetuje za vrijeme liječenja.
• if your child is allergic to stiripentol or to any of the other ingredients of Diacomit.
• ako je Vaše dijete alergično na stiripentol ili na neki drugi sastojak Diacomita.
Uncommon Rare
Manje često Rijetk0
It is used in conjunction with clobazam and valproate (other antiepileptic medicines) to treat a certain form of epilepsy called severe myoclonic epilepsy in infancy (Dravet's syndrome), which affects children.
Koristi se dodatno uz klobazam i valproat (druge antiepileptike) u liječenju određenog oblika epilepsije koji se naziva teška mioklona epilepsija u djetinjstvu (Dravetov sindrom), koja pogađa djecu.
Studies in the rat on fertility and general reproductive performance and on pre- and postnatal development were uneventful except for a minor reduction in the survival of pups nursed by mothers exhibiting toxic responses to stiripentol at a dose of 800 mg/kg/day (see section 4.6).
Ispitivanja plodnosti i opće reproduktivne sposobnosti u štakora, i prenatalnog i postnatalnog razvoja su bila bez važnih događaja osim male redukcije u preživljavanju mladunaca koji su majke dojile, a koji su pokazali toksični odgovor na stiripentol pri dozi od 800 mg/kg/dan (vidjeti dio 4.6).
In these children, the use of stiripentol will be done under the close supervision of the doctor.
U ove će se djece stiripentol primjenjivati uz strogi nadzor liječnika.
How to take the Diacomit powder for oral suspension The powder should be mixed in a glass of water and should be taken immediately after mixing during the meal.
Kako uzimati Diacomit prašak za oralnu suspenziju Prašak treba razmutiti u čaši vode i uzeti odmah nakon miješanja tijekom obroka.
The daily dosage of clobazam and/or valproate should be reduced according to the onset of side effects whilst on stiripentol therapy (see section 4.2).
Dnevne doze klobazama i/ili valproata treba smanjiti u skladu s javljanjem nuspojava u tijeku liječenja stiripentolom (vidjeti dio 4.2).
In case stiripentol therapy is continued during breast-feeding, the breast-fed infant should be carefully observed for potential adverse effects.
U slučaju da je liječenje stiripentolom nastavljeno tijekom dojenja, dojenče treba pomno promatrati zbog mogućih nuspojava.
The increase in steady state levels with the combined use of stiripentol, valproate, and clobazam is similar in adults and children, though inter-individual variability is marked.
Porast u koncentracijama u stanju dinamičke ravnoteže u kombiniranoj primjeni stiripentola, valproata i klobazama je sličan u djece i odraslih, iako je interindividualna varijabilnost znatna.
If your child takes more Diacomit than he or she should Contact your child's doctor if you know or think your child has taken more medicine than he or she should have.
Ako Vaše dijete uzme više Diacomita nego što bi smjelo Obratite se djetetovom liječniku ako znate ili mislite da je Vaše dijete uzelo više lijeka nego što je trebalo.
The combination with Diacomit should be avoided as it may increase their blood levels, leading to digestive disorders, racing heart and insomnia.
Treba izbjegavati kombiniranje s Diacomitom, jer može povećati njihovu razinu u krvi, što izaziva probavne smetnje, lupanje srca i nesanicu.
There are no clinical study data to support the use of stiripentol as monotherapy in Dravet's syndrome.
Nema podataka iz kliničkih studija koji bi poduprli primjenu stiripentola kao monoterapije u Dravetovom sindromu.
Stiripentol has also been shown to enhance GABAA receptor-mediated transmission in the immature rat hippocampus and increase the mean open-duration (but not the frequency) of GABAA receptor chloride channels by a barbiturate-like mechanism.
Pokazano je također da u hipokampusu mladih štakora stiripentol povećava GABAA transmisiju posredovanu receptorima i povećava srednju vrijednost trajanja otvorenosti (ali ne učestalost) kloridnih kanala u GABAA receptoru, mehanizmom sličnim kao u barbiturata.
Increased risk of dose-dependent adverse reactions such as rhabdomyolysis (decreased hepatic metabolism of cholesterol-lowering medicinal product).
Povećanje rizika od nuspojava ovisnih o dozi kao što je rabdomioliza (smanjen hepatički metabolizam lijeka koji snižava razinu kolesterola).
The second effect of stiripentol is mainly based on metabolic inhibition of several isoenzymes, in particular CYP450 3A4 and 2C19, involved in the hepatic metabolism of other anti-epileptic medicines.
Drugi učinak stiripentola se uglavnom temelji na metaboličkoj inhibiciji nekoliko izoenzima, a osobito CYP450 3A4 i 2C19, uključenih u hepatički metabolizam drugih antiepileptičkih lijekova.
It is well absorbed by the oral route since the majority of an oral dose is excreted in urine.
Dobro se apsorbira uzet peroralno jer se glavnina oralne doze izlučuje urinom.
The daily dosage may be administered in 2 or 3 divided doses.
Dnevna doza može se primijeniti u 2 ili 3 podijeljene doze.
Clearance and volume of distribution were related to body weight by an allometric model with exponents of 0.433 and 1, respectively: as body weight increased from 10 to 60 kg, apparent oral clearance increased from 2.60 to 5.65 L/hr and apparent volume of distribution increased from 32.0 to 191.8 L. As a result, elimination half-life increased from 8.5hr (for 10 kg) to 23.5 hr (for 60 kg).
Klirens i volumen distribucije su bili u odnosu s tjelesnom težinom, prikazano alometrijskim modelom s eksponentom 0,433 i 1: kako se tjelesna težina povećavala od 10 do 60 kg, prividni oralni klirens se povećavao od 2,60 to 5,65 L/h, a prividni volumen distribucije se povećavao od 32,0 to 191,8 L.
Diplopia
Diplopija
• if your child has kidney or liver problems.
• ako Vaše dijete ima problema s bubrezima ili jetrom.
Pharmacotherapeutic group: Antiepileptics, other antiepileptics, ATC code: N03AX17
Farmakoterapijska skupina: antiepileptici, drugi antiepileptici, ATK oznaka: N03AX17
The influence of other antiepileptic medicinal products on stiripentol pharmacokinetics is not well established.
Utjecaj drugih antiepileptičkih lijekova na farmakokinetiku stiripentola nije dovoljno utvrđen.
How to take the Diacomit capsules
Kako uzimati Diacomit kapsule
Stopping treatment suddenly can lead to an outbreak of seizures.
Nagli prekid terapije može dovesti do pojave napadaja.
Stiripentol is an inhibitor of the enzymes CYP2C19, CYP3A4 and CYP2D6 and may markedly increase the plasma concentrations of substances metabolised by these enzymes and increase the risk of adverse reactions (see section 4.5).
Stiripentol je inhibitor enzima CYP2C19, CYP3A4 i CYP2D6 i može znatno povećati koncentracije u plazmi tvari koje se metaboliziraju ovim enzimima i povećati rizik od nuspojava (vidjeti dio 4.5).
In the event of clinical signs of adverse reactions or overdose of clobazam (i.e., drowsiness, hypotonia, and irritability in young children), this daily dose was reduced by 25% every week.
U slučaju kliničkih znakova nuspojava ili predoziranja klobazamom (to jest, pospanosti, hipotonije, te razdražljivosti u male djece), ova dnevna doza je smanjivana svakog tjedna za 25%.
These substances should not be used in conjunction with stiripentol in the management of Dravet's syndrome.
Ove tvari ne smiju se uzimati zajedno sa stiripentolom u liječenju Dravetovog sindroma.
Effect of stiripentol on cytochrome P450 enzymes
Utjecaj stiripentola na enzime citokroma P450
• rash, skin allergy, urticaria (pinkish, itchy swellings on the skin);
• osip, kožna alergija, urtikarija (ružičaste otekline na koži koje svrbe);
Within each frequency grouping, undesirable effects are presented in order of decreasing severity.
Unutar svake grupe učestalosti nuspojave su prikazane po redu opadanja težine.
90 hard capsules
90 tvrdih kapsula
However, some patients may experience dizziness and ataxia that may affect ability to drive and use machines and patients should not drive or use machinery whilst on stiripentol therapy.
Međutim, neki bolesnici mogu iskusiti omaglicu i ataksiju koje mogu utjecati na sposobnost upravljanja vozilima i rada sa strojevima te bolesnici na terapiji stiripentolom ne bi trebali upravljati vozilima i raditi sa strojevima.
Photosensitivity, rash, cutaneous allergy, urticaria
Fotosenzitivnost, osip, kožna alergija, urtikarija
• nausea, vomiting;
• mučnina, povraćanje;
Neutropenia may be associated with the administration of stiripentol, clobazam and valproate.
Neutropenija može biti povezana s primjenom stiripentola, klobazama i valproata.
Your child must NOT take Diacomit
Vaše dijete NE smije uzimati Diacomit
phenobarbital, primidone, phenytoin, carbamazepine, diazepam.
fenobarbital, primidon, fenitoin, karbamazepin, diazepam. - lijekove koji sadrže:
Pharmacotherapeutic group: Antiepileptics, other antiepileptics, ATC code: N03AX17 Mechanism of action
Farmakoterapijska skupina: antiepileptici, drugi antiepileptici, ATK oznaka: N03AX17 Mehanizam djelovanja
Read all of this leaflet carefully before your child starts taking this medicine because it contains important information for you.
Vaše dijete počne uzimati ovaj lijek jer sadrži Vama važne podatke.
It is recommended that if a switch of formulations is required this is done under clinical supervision, in case of problems with tolerability (see section 5.2).
Preporuka je da se u slučaju potrebe za zamjenom farmaceutskih oblika zamjena radi pod kliničkim nadzorom zbog problema s podnošenjem lijeka (vidjeti dio 5.2).
s r.o Opletalova 25
Desitin Pharma spol. s r.o Opletalova 25
Boxes of 30, 60 and 90 sachets.
Kutije od 30, 60 i 90 vrećica.
In view of the lack of genotoxicity of stiripentol and the well-known, special susceptibility of the mouse liver to tumour formation in the presence of hepatic enzyme induction, this finding is not considered to indicate a risk of tumorigenicity in patients.
Glede nedostatka genotoksičnosti stiripentola, a dobro poznate, osobite podložnosti mišje jetere ka stvaranju tumora u prisustvu indukcije hepatičkih enzima, ne smatra se da ovaj nalaz ukazuje na rizik od tumora u ljudi.
Toxicity studies in animals (rat, monkey, mouse) have not revealed any consistent pattern of toxicity apart from liver enlargement associated with hepatocellular hypertrophy, which occurred when high doses of stiripentol were administered to both rodents and non-rodents.
Istraživanja toksičnosti u životinja (štakora, majmuna, miševa) nisu otkrila dosljedan obrazac toksičnosti osim povećanja jetre udruženog s hepatocelularnom hipertrofijom, koja se javljala kad su visoke doze stiripentola primjenjivane i na glodavce i na ne-glodavce.
After a baseline period of 1 month, placebo (n=20) or stiripentol (n=21) was added to valproate and clobazam during a double-blind period of 2 months.
Nakon početnog perioda od 1 mjeseca, placebo (n=20) ili stiripentol (n=21) je dodan valproatu i klobazamu tijekom dvostruko slijepog perioda od 2 mjeseca.
The data were best fitted with a one compartment model with first order absorption and elimination processes.
Podaci su se najbolje uklopili u model jednog odjeljka s apsorpcijom i eliminacijom koje odgovaraju kinetici prvog reda.
The following pharmacokinetic properties of stiripentol have been reported from studies in adult healthy volunteers and adult patients.
Sljedeća farmakokinetička svojstva stiripentola su zabilježena iz ispitivanja na odraslim zdravim dobrovoljcima i odraslim bolesnicima.
You can also report side effects directly via the national reporting system listed in Appendix V.
Nuspojave možete prijaviti izravno putem nacionalnog sustava za prijavu nuspojava: navedenog u Dodatku V*.
Breast-feeding is not recommended during treatment with this medicine.
Tijekom liječenja ovim lijekom, dojenje se ne preporučuje.
Data on the potential for inhibition of CYP1A2 are limited, and therefore, interactions with theophylline and caffeine cannot be excluded because of the increased plasma levels of theophylline and caffeine which may occur via inhibition of their hepatic metabolism, potentially leading to toxicity.
Oskudni su podaci o mogućoj inhibiciji CYP1A2, te se stoga ne mogu isključiti interakcije s teofilinom i kofeinom zbog povećanih razina teofilina i kofeina u plazmi, koje mogu nastati inhibicijom njihovog hepatičkog metabolizma, što potencijalno može dovesti do toksičnosti.
Paediatric population The dose of stiripentol is calculated on a mg/kg body weight basis.
Pedijatrijska populacija Doza stripentola izračunava se na temelju doziranja u mg/kg tjelesne težine.
The most common side effects with stiripentol are anorexia, weight loss, insomnia, drowsiness, ataxia, hypotonia and dystonia.
Najčešće nuspojave kod primjene stiripentola su anoreksija, gubitak na težini, nesanica, pospanost, ataksija, hipotonija i distonija.
41 children with SMEI were included in a randomised, placebo-controlled, add-on trial.
41 dijete sa SMEI je bilo uključeno u randomiziranu placebo kontroliranu studiju dodatne terapije.
Diacomit contains aspartame, glucose, sorbitol and sodium This medicine contains 2.5 mg aspartame in each 250mg-sachet and 5 mg each 500mg-sachet.
Diacomit sadrži aspartam, glukozu, sorbitol i natrij Ovaj lijek sadrži 2,5 mg aspartama u svakoj vrećici od 250 mg i 5 mg u svakoj vrećici od 500 mg.
- Immunosuppressants (tacrolimus, cyclosporine, sirolimus) Raised blood levels of immunosuppressants (decreased hepatic metabolism).
- Imunosupresivi (takrolimus, ciklosporin, sirolimus) Povećanje razine imunosupresiva u krvi (smanjen hepatički metabolizam).
DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date of first authorization: 04 January 2007
Datum prvog odobrenja: 04. siječnja 2007.
Monitoring of plasma concentrations or adverse reactions is recommended.
Preporučuje se nadzor koncentracija u plazmi i nuspojava.
60 sachets
60 vrećica
• Because the frequency of gastrointestinal side effect with Diacomit, clobazam and valproate,
• Zbog učestalih gastrointestinalnih nuspojava kod uzimanja Diacomita, klobazama i valproata,
Given the frequency of gastrointestinal adverse reactions to treatment with stiripentol and valproate (anorexia, loss of appetite, nausea, vomiting), the growth rate of children under this combination of treatment should be carefully monitored.
S obzirom na učestalost gastrointestinalnih nuspojava u liječenju stiripentolom i valproatom (anoreksija, gubitak teka, mučnina, povraćanje), treba pomno nadzirati brzinu rasta u djece liječene kombinacijom ovih lijekova.
This medicine contains sorbitol: 2.4 mg in each 250mg-sachet and 4.8 mg in each 500mg-sachet.
Ovaj lijek sadrži sorbitol: 2,4 mg u svakoj vrećici od 250 mg i 4,8 mg u svakoj vrećici od 500 mg.
The powder should be mixed in a glass of water and should be taken immediately after mixing during a meal.
Prašak treba razmutiti u čaši vode i popiti odmah nakon miješanja tijekom obroka.
Responders were defined as having more than 50% reduction in the frequency of clonic (or tonicclonic) seizures during the second month of the double-blind period compared with baseline.
Bolesnici s odgovorom su definirani kao oni koji su imali više od 50% smanjenja učestalosti kloničkih ( ili toničko-kloničkih) napadaja tijekom drugog mjeseca dvostruko slijepog perioda u usporedbi s početnim periodom.
90 sachets
90 vrećica
• raised levels of liver enzymes, especially when given with either of the antiepileptic medicines carbamazepine and sodium valproate;
• povišene razine jetrenih enzima, posebno ako se lijek uzima s bilo kojim od dva antiepileptička lijeka - karbamazepinom i natrijevim valproatom;
If your child forgets to take Diacomit
Ako Vaše dijete zaboravi uzeti Diacomit
* Thrombocytopenia data are derived from both clinical trials and post-marketing experience.
* Podaci o trombocitopeniji su dobivenii iz kliničkih ispitivanja i postmarketinškog iskustva.
- Cisapride, halofantrine, pimozide, quinidine, bepridil Increased risk of cardiac arrhythmias and torsades de pointes/wave burst arrhythmia in particular.
- Cisaprid, halofantrin, pimozid, kinidin, bepridil Povećanje rizika od srčanih aritmija, a osobito od ventrikularne aritmije tipa torsades de pointes.
Patients aged ≥ 18 years of age
≥ 18 godina
There are no clinical study data to support the clinical safety of stiripentol administered at daily doses greater than 50 mg/kg/day.
Nema podataka iz kliničkih studija koji bi poduprli kliničku sigurnost stiripentola primijenjenog u dnevnim dozama većim od 50 mg/kg/danu.
With regard to topiramate, it is considered that potential competition of inhibition on CYP2C19 should not occur because it probably requires plasma concentrations 5-15 times higher than plasma concentrations obtained with the standard recommended topiramate dose and dosage schedules.
Smatra se da moguća kompeticija inhibicije CYP2C19 ne nastaje zato što vjerojatno zahtijeva koncentracije u plazmi 5-15 puta veće nego koncentracije koje se dostižu standardnim preporučenim dozama topiramata i njegovim rasporedom uzimanja.
Size 2 pink capsule
Ružičasta kapsula veličine 2
At therapeutic concentrations, stiripentol significantly inhibits several CYP450 isoenzymes: for example, CYP2C19, CYP2D6 and CYP3A4.
U terapijskim koncentracijama, stiripentol značajno inhibira nekoliko CYP450 izoenzima, na primjer CYP2C19, CYP2D6 i CYP3A4.
Clinical monitoring of plasma levels of other anticonvulsants when combined with stiripentol with possible dose adjustments is recommended.
Savjetuje se kliničko praćenje razina drugih antikonvulziva u plazmi i eventualna prilagodba doza pri kombiniranju sa stiripentolom.
Stiripentol must always be taken with food as it degrades rapidly in an acidic environment (e.g. exposure to gastric acid in an empty stomach).
Stiripentol se uvijek mora uzimati s hranom jer se brzo razgrađuje u kiselom okolišu (kao što je izloženost želučanoj kiselini u praznom želucu).
Potential medicinal product interactions affecting stiripentol
Moguće interakcije s drugim lijekovima koje utječu na stiripentol
In view of the indication, administration of stiripentol during pregnancy and in women of childbearing potential would not be expected.
S obzirom na indikaciju, ne očekuje se primjena stiripentola tijekom trudnoće i u žena koje mogu rađati.
This medicine contains less than 1 mmol sodium (23 mg) per sachet, that is to say essentially ‘sodium-free'.
Ovaj lijek sadrži manje od 1 mmol natrija (23 mg) po vrećici, tj. zanemarive količine natrija.
Do NOT take Diacomit with milk or dairy products (yoghurt, soft cream cheeses, etc), fruit juice, fizzy drinks or food and drinks that contain caffeine or theophylline (for example cola, chocolate, coffee, tea and energy drinks).
NEMOJTE uzimati Diacomit s mlijekom ili mliječnim proizvodima (jogurt, meki krem sirevi, itd.), s voćnim sokom, gaziranim pićima ili hranom i pićima koji sadrže kofein ili teofilin (kao što su kokakola, čokolada, kava, čaj, energetski napitci).
Dose adjustments of other antiepileptics used in combination with stiripentol Despite the absence of comprehensive pharmacology data on potential drug interactions, the following advice regarding modification of the dose and dosage schedules of other anti-epileptic medicinal products administered in conjunction with stiripentol is provided based on clinical experience.
Prilagodba doze ostalih antiepileptika koji se primjenjuju u kombinaciji sa stiripentolom Unatoč nepostojanju sveobuhvatnih farmakoloških podataka o mogućim interakcijama s drugim lijekovima, na temelju kliničkog iskustva se daju sljedeći savjeti glede promjene doze i rasporeda uzimanja drugih antiepileptičkih lijekova koji se primjenjuju istodobno sa stiripentolom.
MINIMUM PARTICULARS TO APPEAR ON SMALL IMMEDIATE PACKAGING UNITS SACHET LABEL TEXT
PODACI KOJE MORA NAJMANJE SADRŽAVATI MALO UNUTARNJE PAKIRANJE TEKST NA VREĆICI
Based on the clinical observations in this group of patients, there is no evidence to suggest that a change in topiramate dose and dosage schedules is needed if coadministered with stiripentol.
Na temelju kliničkog promatranja ove skupine bolesnika, nije bilo dokaza koji bi ukazali na potrebu za promjenom doze ili rasporeda uzimanja topiramata pri istodobnoj primjeni sa stiripentolom.
BIOCODEX 1 avenue Blaise Pascal, 60000 Beauvais FRANCE
BIOCODEX 1 avenue Blaise Pascal, 60000 Beauvais FRANCUSKA
• The capsule shell is made of gelatine, titanium dioxide (E171).
• Ovojnica kapsule se sastoji od želatine, titanijeva dioksida (E171).
Relative bioavailability between the capsules and powder for oral suspension in sachet formulations has been studied in healthy male volunteers after a 1,000 mg single oral administration.
Relativna bioraspoloživost kapsula i praška za oralnu suspenziju u vrećici je istraživana u zdravih muških dobrovoljaca poslije jednokratne peroralne primjene doze od 1000 mg.
If your child has problems with certain ingredients of Diacomit (e.g. aspartame, glucose, sorbitol).
Ako Vaše dijete ima problema s nekim sastojcima Diacomita (na primjer aspartam, glukoza, sorbitol), pogledajte u tom slučaju u daljem tekstu: “ Diacomit sadrži aspartam, glukozu, sorbitol i natrij”.
PARTICULARS TO APPEAR ON THE IMMEDIATE PACKAGING BOTTLE LABEL TEXT
PODACI KOJI SE MORAJU NALAZITI NA UNUTARNJEM PAKIRANJU TEKST NA BOČICI
The powder should be mixed in a glass of water and should be taken immediately after mixing.
Prašak treba razmutiti u čaši vode i popiti odmah nakon miješanja.
Abnormal laboratory findings
Poremećene laboratorijske pretrage
What Diacomit 500 mg contains
Što Diacomit 500 mg sadrži
Paediatric population pharmacokinetic study
Farmakokinetička ispitivanja u pedijatrijskoj populaciji