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Also referred to as within-laboratory reproducibility (38). Outlier An outlier is an observation that is markedly different from other values in a random sample from a population.
Laboratorionsisäinen uusittavuus Se, missä määrin pätevä laboratoriohenkilöstö voi (kyseisessä laboratoriossa) saada onnistuneesti aikaan samat tulokset käyttämällä tiettyä tutkimussuunnitelmaa eri ajankohtina (38).
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Also referred to as within-laboratory reproducibility (33). Outlier An outlier is an observation that is markedly different from other values in a random sample from a population.
Laboratorionsisäinen uusittavuus Se, missä määrin tietyn laboratorion pätevä henkilöstö voi saada onnistuneesti aikaan samat tulokset käyttämällä tiettyä tutkimussuunnitelmaa eri ajankohtina (33).
In certain situations, when there is a regulatory need to confirm a negative prediction of skin sensitising potential, an optional rLLNA protocol (16) (17) (18) using fewer animals may be used, provided there is adherence to all other LLNA protocol specifications in this TM. Before applying the rLLNA approach, clear justifications and scientific rationale for its use should be provided.
Vaihtoehtoista, vähemmän koe-eläimiä käyttävää rLLNA-menetelmää (16) (17) (18) voidaan soveltaa tietyissä tapauksissa, joissa ihoherkistyspotentiaalin negatiivinen oletus on sääntelysyistä vahvistettava, edellyttäen että kaikkia muita tässä testimenetelmässä kuvattuja LLNA-menettelyn vaatimuksia noudatetaan. rLLNA-menettelyn käyttö on perusteltava selvästi ja tieteellisesti ennen menetelmän käyttöä.
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