natgillin/translations-raw huggingface dataset:
Desuden blev hjertefrekvensen reduceret med i gennemsnit 11,0 slag i minuttet (bpm) hos de patienter, som fik Multaq, sammenlignet med en stigning på 0,7 bpm hos de patienter, som fik placebo.
In addition, heart rates reduced by an average of 11.0 beats per minute (bpm) in the patients who took Multaq, compared with a rise of 0.7 bpm in the patients who took placebo.
Desuden blev patienter med type 2-diabetes og svært nedsat nyrefunktion (< 30 ml/min.) sammenlignet med patienter med type 2-diabetes og normal nyrefunktion.
In addition patients with T2DM and severe renal impairment (<30 ml/min) were compared to T2DM patients with normal renal function.
Desuden blev reduktionen i dosis af binyrebarkhormon på 5 mg dagligt anset for klinisk vigtig, selv om den var beskeden, på baggrund af komplikationerne ved langvarig behandling med binyrebarkhormon.
In addition, a reduction in corticosteroid dose of 5 mg daily, although modest, was considered clinically relevant, given the complications of long-term corticosteroid treatment.
Desuden blev to 12-ugers placebokontrollerede studier udført med patienter med utilstrækkeligt kontrolleret type 2-diabetes og hypertension.
Furthermore, two 12- week, placebo-controlled studies were conducted in patients with inadequately controlled type 2 diabetes and hypertension.
Desuden bør effektiv antiepileptisk behandling ikke afbrydes, da forværring af sygdommen er skadelig for både moderen og fosteret.
Moreover, effective antiepileptic therapy must not be interrupted, since the aggravation of the illness is detrimental to both the mother and the foetus.
Desuden bør graviditet undgås i1 måned efter vaccinationen (se pkt.
Furthermore, pregnancy should be avoided for 1 month following vaccination (see section 4.6).
Desuden bør kvinder, der tager Duavive, rådes til at bevæge sig regelmæssigt under rejser, som indebærer langvarig immobilisering.
In addition, women taking DUAVIVE should be advised to move about periodically during travel involving prolonged immobilisation.
Desuden bør lægemidlet gives under nøje overvågning af erfarent sundhedspersonale og et sted, hvor der er umiddelbar adgang til genoplivningsfaciliteter.
In addition, the medicine should be given under the close supervision of an experienced healthcare professional and in an environment where facilities for resuscitating patients are immediately available.
Desuden bør muligheden for QTc-forlængelse og torsades de pointes tages i betragtning.
In addition, the possibility of QTc prolongation and Torsades de pointes should be considered.
Desuden bør patienter advares om risikoen for hypoglykæmi, når Efficib anvendes sammen med sulfonylurinstof eller sammen med insulin.
In addition, patients should be alerted to the risk of hypoglycaemia when Efficib is used in combination with a sulphonylurea or with insulin.
Desuden bør patienter advares om risikoen for hypoglykæmi, når Ristfor anvendes sammen med sulfonylurinstof eller sammen med insulin.
In addition, patients should be alerted to the risk of hypoglycaemia when Ristfor is used in combination with a sulphonylurea or with insulin.
Desuden bør patienter, der er i sunitinibbehandling, observeres tæt for tegn og symptomer på thyroideadysfunktion, og de patienter, som udvikler tegn og/eller symptomer herpå, bør have foretaget laboratorieundersøgelse af thyroideafunktionen.
In addition, patients should be observed closely for signs and symptoms of thyroid dysfunction during treatment, and patients who develop any signs and/or symptoms suggestive of thyroid dysfunction should have laboratory testing of thyroid function performed as clinically indicated.
Desuden bør Zevalin ikke anvendes til patienter med non-Hodgkin’s lymfom, der involverer hjernen og/eller rygmarven, da disse patienter ikke var omfattet af undersøgelserne på mennesker (kliniske studier).
In addition, Zevalin is not recommended for the use in patients with non-Hodgkin’s lymphoma involving the brain and/or spinal cord as those patients were not included in clinical studies.
Desuden er akut eksponering af vernakalant i poor metabolizers af CYP2D6 kun minimalt forskellig i sammenligning med extensive metabolizers.
In addition, acute exposure of vernakalant in poor metabolisers of CYP2D6 is only minimally different when compared to that of extensive metabolisers.
Desuden er bivirkninger fra det understøttende studie, MCL-001, blevet inkluderet i tabel 3.
Additionally, ADRs from supportive study MCL-001 have been included in table 3.
Desuden er BRINAVESS ikke blevet vurderet hos patienter med klinisk betydningsfuld valvulær stenose, hypertrofisk obstruktiv kardiomyopati, restriktiv kardiomyopati eller konstriktiv perikardit og bør ikke anvendes i disse tilfælde.
Furthermore, BRINAVESS has not been evaluated in patients with clinically meaningful valvular stenosis, hypertrophic obstructive cardiomyopathy, restrictive cardiomyopathy, or constrictive pericarditis and its use cannot be recommended in such cases.
Desuden er de tilgængelige dosisstyrker ikke egnet til startbehandling hos børn, der vejer mindre end 25 kg, patienter der ikke er i stand til at sluge tabletter eller til administration af doser under 250 mg.
In addition, the available dose strengths of the tablets are not appropriate for initial treatment in children weighing less than 25 kg, for patients unable to swallow tablets or for the administration of doses below 250 mg.
Desuden er de tilgængelige tabletstyrker ikke egnet til initialbehandling af børn, som vejer mindre end 25 kg, til patienter, som ikke er i stand til at synke tabletter, eller til administration af doser under 250 mg.
In addition, the available dose strengths of the tablets are not appropriate for initial treatment in children weighing less than 25 kg, for patients unable to swallow tablets or for the administration of doses below 250 mg.
Desuden er den tilsvarende hyppighed anført for hver bivirkning efter nedenstående konvention (CIOMS III): meget almindelig (≥1/10); almindelig (≥1/100 til <1/10); ikke almindelig (≥1/1.000 til <1/100); sjælden (≥1/10.000 til <1/1.000); meget sjælden (<1/10.000); ikke kendt (kan ikke estimeres ud fra forhåndenværende data).
In addition, the corresponding frequency category using the following convention (CIOMS III) is also provided for each adverse drug reaction: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); not known: frequency cannot be estimated from the available data.
Desuden er den virksomhed, der fremstiller Gilenya, i færd med at foretage en vurdering af risikoen for hjerte- og kredsløbsproblemer.
In addition, the company that makes Gilenya will carry out a study to assess the risk of side effects on the heart and circulation.
Desuden er der blevet rapporteret en forsinket allergisk hudreaktion (cheilitis) efter længerevarende dermal eksponering (mundskyl).
In addition, a delayed-type allergic skin reaction (cheilitis) after longer-term dermal exposure (mouthwash) has been reported.
Desuden er der blevet rapporteret øjenhævelse, dyspnø og myalgi som bivirkninger med oral palonosetron, men de blev ikke observeret i løbet af udviklingen af Akynzeo.
In addition eye swelling, dyspnoea and myalgia as adverse reactions have been reported with oral palonosetron but not observed during the development of Akynzeo.
Desuden er der efter markedsføring rapporteret om en pludselig alvorlig allergisk reaktion (anafylaktisk chok) med Trevaclyn og/eller andre nicotinsyrepræparater (alene og/eller sammen med visse andre kolesterolsænkende lægemidler).
Additionally, the following were reported during post-marketing experience with Trevaclyn and/or other nicotinic acid products (alone and/or with certain other cholesterol-lowering medicines). a sudden serious allergic reaction (anaphylactic shock).
Desuden er der rapporteret en del forskellige bivirkninger ved anvendelse af enten Merck PRP-OMPC vaccine eller Merck Hepatitis B (rekombinant) vaccine efter markedsføring hos spædbørn og børn i alderen op til 71 måneder.
In addition, a variety of adverse effects have been reported with marketed use of either Merck PRP- OMPC Vaccine or Merck Hepatitis B (Recombinant) Vaccine in infants and children through 71 months of age.
Desuden er der set forbigående, moderate fald i ikke–fastende blodglukose.
Transient, moderate decreases in non-fasting blood glucose have also been seen.
Desuden er det blevet påvist, at flåterne falder hurtigere af behandlede hunde, hvilket indirekte mindsker risikoen for overførsel af visse flåtbårne sygdomme til hunde fra smittebærende flåter.
In addition, it has been shown that ticks detach more quickly from treated dogs, which indirectly reduces the risk of transmission of certain tick- borne diseases to dogs from infected ticks.
Desuden er det ikke fastslået, i hvilket omfang Vizamyl er egnet til at forudsige forløbet af Alzheimers sygdom hos patienter med hukommelsesproblemer eller til at overvåge behandlingens gavnlige virkning for patienterne.
In addition, the usefulness of Vizamyl in predicting the development of Alzheimer’s disease in patients with memory problems or in monitoring patients’ response to treatment has not been established.
Desuden er det ikke fastslået, i hvor høj grad Amyvid er egnet til at forudsige Alzheimers sygdom hos patienter med hukommelsesproblemer eller til at overvåge patienternes respons på behandlingen.
In addition, the usefulness of Amyvid in predicting the development of Alzheimer’s disease in patients with memory problems or in monitoring patients’ response to treatment has not been established.
Desuden er det ikke fastslået, i hvor høj grad Neuraceq er egnet til at forudsige forløbet af Alzheimers sygdom hos patienter med hukommelsesproblemer eller til at overvåge patienternes respons på behandlingen.
In addition, the usefulness of Neuraceq in predicting the development of Alzheimer’s disease in patients with memory problems or in monitoring patients’ response to treatment has not been established.
Desuden er det kontraindiceret hos patienter, der tidligere har haft akutte og alvorlige overfølsomhedsreaktioner (f.eks. en anafylaktisk reaktion) over for et hvilket som helst andet betalaktamantibiotikum (se pkt.
In addition, it is contraindicated in patients with a history of an immediate and severe hypersensitivity (e.g. anaphylactic reaction) to any other type of beta-lactam antibacterial agent (see section 4.3).
Desuden er det særligt vigtigt, at du fortæller lægen, hvis du også bruger nogle af følgende lægemidler, da de kan nedsætte virkningen af irinotecan:
It is also especially important that you tell your doctor if you are also taking the following medicines, since they reduce the availability of irinotecan in your body:
Desuden er det vigtigt for dig at vide, at
Furthermore, it is important for you to know that:
Desuden er det vist, at epoetin alfa i doser på 75 til 150 IE/kg ugentligt opretholder hæmatokritniveauer på 36 til 38 % i op til seks måneder.
Moreover, epoetin alfa doses of 75 to 150 IU/kg per week have been shown to maintain haematocrits of 36 to 38% for up to six months.
Desuden er en eller flere af følgende symptomer set som del af en allergisk reaktion over for Trevaclyn.
In addition, one or more of the following symptoms have been reported as part of an allergic reaction to Trevaclyn.
Desuden er en forbigående stigning i kropstemperaturen på vaccinationsdagen på ca.
Moreover, a transient increase in body temperature on the day of vaccination of about
Desuden er en K70E-substitution i hiv 1-revers transkriptase blevet selekteret af tenofovir, og det forårsager nedsat følsomhed for abacavir, emtricitabin, tenofovir og lamivudin på lavt niveau.
In addition, a K70E substitution in HIV-1 reverse transcriptase has been selected by tenofovir and results in low-level reduced susceptibility to abacavir, emtricitabine, tenofovir and lamivudine.
Desuden er en K70E-substitution i hiv 1-revers transkriptase blevet selekteret klinisk af tenofovirdisoproxilfumarat og resulterer i en lav grad af nedsat følsomhed for abacavir, emtricitabin, tenofovir og lamivudin.
In addition, a K70E substitution in HIV-1 reverse transcriptase has been selected clinically by tenofovir disoproxil fumarate and results in low-level reduced susceptibility to abacavir, emtricitabine, tenofovir, and lamivudine.
Desuden er en tredje undersøgelse i gang hos 5 623 patienter, hvor tidligere behandling med en anden sygdomsmodificerende behandling (glatirameracetat, beta-interferon eller fingolimod)ikke har virket.
In addition, a third study is ongoing in 5,623 patients where previous treatment with another disease-modifying therapy had failed (glatiramer acetate, beta-interferon or fingolimod).
Desuden er følgende bivirkninger set efter markedsføringen.
In addition, the following side effects have been identified during post-marketing experience.
Desuden er følgende set ved behandling med IntronA: Vogt-Koyanagi-Harada syndrom (en autoimmun inflammatorisk lidelse, der påvirker øjnene, huden og membraner i ører, hjerne og rygmarv), tanker om at true andre mennesker på livet, mani (unormalt stor eller unødvendig entusiasme), bipolare lidelser (humørsvingninger karakteriseret ved vekslende episoder af tungsind og begejstring), hjertesvigt, perikardie-effusion (væskeansamling mellem perikardiet (hjertesækken) og selve hjertet) samt lungefibrose (dannelse af arvæv i lungerne).
Additionally, Vogt-Koyanagi-Harada syndrome (an autoimmune inflammatory disorder affecting the eyes, skin and the membranes of the ears, brain and spinal cord), thoughts about threatening the life of others, mania (excessive or unreasonable enthusiasm), bipolar disorders (mood disorders characterized by alternating episodes of sadness and excitement), congestive heart failure, pericardial effusion (a fluid collection that develops between the pericardium (the lining of the heart) and the heart itself), and pulmonary fibrosis (scarring of the lungs) have been reported with IntronA use.
Desuden er graft versus host disease (GvHD) blevet rapporteret (se pkt. c nedenfor).
Graft versus Host Disease (GvHD) has also been reported (see section c below).
Desuden er sløret syn anført som en yderligere ADR forbundet med timololkomponenten i Ganfort i CCDS.
Furthermore, Vision blurred is listed as an additional ADR associated with the timolol component of Ganfort in the CCDS.
Desuden er virusresistens over for Sovaldi meget ualmindelig, og Sovaldi virker mod alle typer hepatitis C-virus.
In addition, virus resistance to Sovaldi is very uncommon and Sovaldi works against all types of hepatitis C virus.
Desuden evaluerede studie I den hæmostatiske virkning ved behandling af blødningsepisoder og fastlagde den hæmostatiske virkning ved perioperativ behandling hos forsøgspersoner, der gennemgik større kirurgiske indgreb.
In addition, study I evaluated haemostatic efficacy in the treatment of bleeding episodes; and determined haemostatic efficacy during perioperative management in subjects undergoing major surgical procedures.
Desuden evaluerede studie I hæmostatisk virkning ved behandling af blødningsepisoder, og fastlagde hæmostatisk virkning ved perioperativ behandling af forsøgspersoner, der gennemgik større kirurgiske indgreb.
In addition, study I evaluated haemostatic efficacy in the treatment of bleeding episodes; and determined haemostatic efficacy during perioperative management in subjects undergoing major surgical procedures.
Desuden fandt udvalget, at da Ravicti fås som en væske, kan dette gøre lægemidlet mere velsmagende, specielt for børn, sammenlignet med andre lægemidler, der fås som granulat til tilsætning til maden; den flydende formulering letter også indgivelse via sonde til patienter, der ikke kan synke pga. neurologiske problemer.
Additionally, the Committee considered that since Ravicti is available as a liquid this could make the medicine more palatable especially for children, compared with other medicines available as granules to be added to food; the liquid formulation also facilitates its administration via tube to patients unable to swallow because of neurological problems.
Desuden fik 37 % af de patienter, der fik Constella, væsentlig eller fuldstæn- dig lindring af symptomerne i mindst 6 ud af de 12 ugers behandling, sammenholdt med 19 % af dem, der fik placebo.
In addition, 37% of patients who received Constella were considerably or completely relieved from symptoms for at least 6 out of the 12 weeks of treatment, compared with 19% of patients who received placebo.
Desuden fik signifikant færre patienter behandlet med cetuximab anden-linje- behandling.
In addition, significantly fewer patients treated with cetuximab received second-line therapy.
Desuden fik to kvindelige kræftpatienter i compassionate use- programmet (på udleveringstilladelser) myokardieinfarkt efter mobilisering af hæmatopoietiske stamceller med plerixafor og G-CSF.
Additionally, two female oncology patients in the compassionate use programme experienced myocardial infarction following haematopoietic stem cell mobilisation with plerixafor and G-CSF.
Desuden findes pakninger, der indeholder 6 hvide blisterkort (60 x 1) som perforerede aluminiums enkeltdosis- blistre.
Furthermore, cartons containing 6 blister strips (60 x 1) in perforated aluminium unit dose white blisters.
Desuden findes pakninger, der indeholder 6 hvide blisterkort (60 x 1) som perforerede aluminiums enkeltdosis-blistre.
Furthermore, cartons containing 6 blister strips (60 x 1) in perforated aluminium unit dose white blisters.
Desuden forbedrede fesoterodin den gennemsnitlige ændring i den ud- tømte mængde pr. vandladning, og den gennemsnitlige ændring i antallet af kontinente dage pr. uge (se Tabel 1 nedenfor).
Furthermore, fesoterodine improved the mean change in the voided volume per micturition, and the mean change in the number of continent days per week (see Table 1 below).
Desuden forekom der reaktioner på injektionsstedet (kløe), lave blodsukkerniveauer (når det blev anvendt sammen med et sulfonylurinstof) og hovedpine.
In addition, reactions at the site of injection (itching and redness), low blood sugar levels (when used with a sulphonylurea) and headache occurred.
Desuden fungerer imepitoin som en svag calciumkanalblokker, hvilket kan bidrage til dets antikonvulsive egenskaber.
In addition, imepitoin has a weak calcium channel blocking effect which may contribute to its anticonvulsive properties.
Desuden fås tabletterne i enkeltdosisblister i pakningsstørrelserne 30 x 1,
Additionally, the tablets are also available in unit dose blister for the pack size of 30x1, 60x1 and 100x1 tablets.
Desuden fås til alle aldersgrupper til administration to gange dagligt en oral suspension (se det pågældende produktresumé).
Furthermore, an immediate- release oral suspension dosage form is available for all age groups for a twice daily administration (please refer to the respective Summary of Product Characteristics).
Desuden har den væsentligste metabolit af osateronacetat (15β- hydroxyleret-osateronacetat) anti-androgene egenskaber.
Also, the major metabolite of osaterone acetate (15-hydroxylated - osaterone acetate) has anti-androgenic activity.
Desuden har i alt 169 sager, været associeret med et antidepressivt middel og 27 sager med antipsykotika midler, 48.5% og henholdsvis 55.5% rapporterede manglende virkning mens de fik orlistat 60 mg i forbindelse med antidepressiva, antipsykotika og lithium.
In addition, a total of 169 cases have been associated with an antidepressant and 27 cases with antipsychotics, 48.5% and 55.5% respectively, reported lack of efficacy while receiving orlistat 60 mg in association with antidepressants, antipsychotics and lithium.
Desuden har patienter, der testede positive for antistoffer mod lægemidlet, ikke vist tegn på overfølsomhed eller takyfylaksi ved administration af asfotase alfa.
Furthermore, patients confirmed positive for anti-drug antibodies have not shown signs of hypersensitivity or tachyphylaxis with asfotase alfa administration.
Desuden har patienter, der testede positive for antistoffer, ikke vist tegn på overfølsomhed eller takyfylaksi efter subkutan administration af asfotase alfa.
Furthermore, patients confirmed positive for antibodies have not shown signs of hypersensitivity or tachyphylaxis following subcutaneous administration of asfotase alfa.
Desuden havde 49% af sunitinib-patienterne tumorer uden funktion versus 52% af placebo-patienterne, og 92% af patienterne i begge behandlingsarme havde levermetastaser.
Additionally, 49% of sunitinib patients had non-functioning tumours versus 52% of placebo patients and 92% patients in both arms had liver metastases.
Desuden hæmmede emtricitabin ikke uridine-5’-diphosphoglucuronyltransferase (UGT), det enzym, der er ansvarligt for glucuronidation.
Also, emtricitabine did not inhibit uridine-5’-diphosphoglucuronyl transferase (UGT), the enzyme responsible for glucuronidation.
Desuden hæmmede raltegravir den virale replikation i kulturer af mitogenaktiverede mononukleære celler fra humant perifert blod inficeret med forskellige, primære kliniske isolater af hiv-1, inklusive isolater fra 5 non-B-subtyper, og isolater, som var resistente over for reverse transkriptasehæmmere og proteasehæmmere.
In addition, raltegravir inhibited viral replication in cultures of mitogen-activated human peripheral blood mononuclear cells infected with diverse, primary clinical isolates of HIV-1, including isolates from 5 non-B subtypes, and isolates resistant to reverse transcriptase inhibitors and protease inhibitors.
Desuden hæmmer pomalidomid proliferation af lenalidomid-resistente myelomatose-cellelinjer og virker synergistisk med dexamethason på induktion af tumorcelle-apoptose i både lenalidomid-følsomme og lenalidomid- resistente cellelinjer.
Additionally, pomalidomide inhibits the proliferation of lenalidomide-resistant multiple myeloma cell lines and synergises with dexamethasone in both lenalidomide-sensitive and lenalidomide-resistant cell lines to induce tumour cell apoptosis.
Desuden hæmmer tazobactam ikke følgende typer beta-lactamaser:
In addition tazobactam does not inhibit the following types of beta-lactamase:
Desuden indikerer flere prækliniske studier, at der er en negativ feedback- mekanisme på molekylærniveau, der begrænser BMP'ers knogleinduktion.
In addition, several non-clinical studies indicate that there is a negative feedback mechanism at the molecular level that limits bone induction by BMPs.
Desuden indsender virksomheden resultaterne af undersøgelser med henblik på yderligere at karakterisere, hvilke patienter Vectibix virker bedst hos.
In addition, the company will provide the results of studies to try to further characterise those patients who respond better to Vectibix.
Desuden kan anden medicin påvirke virkningen af Myocet.
Also some other medicines can affect the way Myocet works.
Desuden kan blødningen komme igen, når lægemidlet ikke længere anvendes.
Bleeding can also come back after the medicine is stopped.
Desuden kan der anvendes 50 mg to gange om ugen i de første 12 uger af behandlingen af plaque-psoriasis.
Treatment with 50 mg twice a week can also be used during the first 12 weeks of treatment for plaque psoriasis.
Desuden kan der gives et peroralt antihistamin f.eks. difenhydramin 50 mg og et analgetikum f.eks. paracetamol 500 mg.
In addition, an oral antihistamine, e.g. diphenhydramine 50 mg, and an analgesic, e.g. paracetamol 500 mg, may be given.
Desuden kan der ofte opstå systemiske symptomer såsom sløvhed og en nedsættelse af appetitten, hvilket sommetider ledsages af feber og en stiv gang.
In addition, systemic signs, such as lethargy and a reduction in appetite may also commonly occur, sometimes accompanied by pyrexia and a stiff gait.
Desuden kan det dræbe visse typer flåter, hvis de er til stede, når lægemidlet påføres.
It may also kill certain types of ticks if they are present when the medicine is applied.
Desuden kan Imatinib Accord 100 mg tabletter fås i perforeret enhedsdosis-blister af PVC/PVdC/alu i pakningsstørrelser med 30 x 1, 60 x 1, 90 x 1, 120 x 1 eller 180 x 1 filmovertrukne tabletter.
Additionally Imatinib Accord 100 mg tablets are available in perforated unit dose blister packs (PVC/PVdC/Alu) containing 30x1, 60x1,90x1, 120x1 or 180x1 film-coated tablets.