natgillin/translations-raw huggingface dataset:
Da effekten af EMEND på oralt administrerede CYP3A4-substraters farmakokinetik er større end EMENDs effekt på intravenøst administrerede CYP3A4-substraters famakokinetik, kan interaktion med oralt administrerede kemoterapeutika, som metaboliseres primært eller delvist af CYP3A4 (fx etoposid, vinorelbin) ikke udelukkes.
Because the effect of EMEND on the pharmacokinetics of orally administered CYP3A4 substrates is greater than the effect of EMEND on the pharmacokinetics of intravenously administered CYP3A4 substrates, an interaction with orally administered chemotherapeutic medicinal products metabolised primarily or partly by CYP3A4 (e.g., etoposide, vinorelbine) cannot be excluded.
Da effekten af Gardasil 9 ikke kunne blive evalueret mod placebo, blev følgende eksplorative analyser udført.
Since the efficacy of Gardasil 9 could not be evaluated against placebo, the following exploratory analyses were conducted.
Da effekten af lavdosiseksponering af imatinib hos spædbarnet er ukendt, bør kvinder, der tager imatinib, ikke amme.
However, since the effects of low-dose exposure of the infant to imatinib are unknown, women taking imatinib should not breast- feed.
Da effekten af produktet på fertilitet, klækkeevne og kyllingernes levedygtighed ikke er blevet undersøgt, frarådes brug hos avlsfugle, der producerer æg til slagtekyllinger eller som erstatningsæglæggere.
As the effect of the product on egg fertility, hatchability and chick viability has not been investigated, use in breeding birds producing eggs for broiler stock or as replacement layers is not recommended.
Da Efficib indeholder metforminhydrochlorid, bør behandlingen seponeres 48 timer før elektiv operation med generel, spinal eller epidural anæstesi.
As Efficib contains metformin hydrochloride, the treatment should be discontinued 48 hours before elective surgery with general, spinal or epidural anaesthesia.
Da eliglustat forventes at forårsage milde stigninger i EKG-intervaller ved væsentligt forhøjede plasmakoncentrationer, bør anvendelsen af Cerdelga undgås hos patienter med hjertesygdom (hjerteinsufficiens, nyligt akut myokardieinfarkt, bradykardi, hjerteblok, ventrikulær arytmi), langt QT-syndrom og i kombination med klasse IA (f.eks. quinidin) og klasse III (f.eks. amiodaron, sotalol) antiarytmika.
Because eliglustat is predicted to cause mild increases in ECG intervals at substantially elevated plasma concentrations, use of Cerdelga should be avoided in patients with cardiac disease (congestive heart failure, recent acute myocardial infarction, bradycardia, heart block, ventricular arrhythmia), long QT syndrome, and in combination with Class IA (e.g. quinidine) and Class III (e.g. amiodarone, sotalol) antiarrhythmic medicinal products.
Da eliminationen af infliximab kan tage op til 6 måneder, bør monitorering fortsæ ttes i denne periode.
Because the elimination of infliximab may take up to six months, monitoring should be continued throughout this period.
Da elvitegravir i høj grad er bundet til plasmaproteiner, er det usandsynligt, at elvitegravir i signifikant grad vil fjernes ved hæmodialyse eller peritonealdialyse.
As elvitegravir is highly bound to plasma proteins, it is unlikely that it will be significantly removed by haemodialysis or peritoneal dialysis.
Da Emtricitabine/Tenofovir disoproxil Zentiva indeholder emtricitabin og tenofovirdisoproxil, kan interaktioner, som er identificeret med disse lægemidler individuelt, forekomme med Emtricitabine/Tenofovir disoproxil Zentiva.
As Emtricitabine/Tenofovir disoproxil Zentiva contains emtricitabine and tenofovir disoproxil , any interactions that have been identified with these agents individually may occur with Emtricitabine/Tenofovir disoproxil Zentiva.
Da en aktiv babesia infektion kan forstyrre udviklingen af beskyttende immunitet, anbefales det at begrænse eksponeringen for flåter i vaccinationsperioden.
As active Babesia infection might interfere with the development of protective immunity it is recommended to reduce exposure to ticks during the period of vaccination.
Da en aktiv babesia infektion kan forstyrre udviklingen af beskyttende immunitet, anbefales det at begrænse eksponeringen for flåter i vaccinationsperioden.
As active babesia infection might interfere with the development of protective immunity, it is recommended to reduce exposure to ticks during the period of vaccination.
Da en godartet forstørrelse af blærehalskirtlen og prostatakræft kan have de samme symptomer, vil Deres læge undersøge Dem for prostatakræft, før De begynder behandlingen med Silodyx.
Since a benign enlargement of the prostate and prostate cancer may present the same symptoms, your doctor will check you for prostate cancer before starting treatment with Silodyx.
Da en godartet forstørrelse af blærehalskirtlen og prostatakræft kan have de samme symptomer, vil Deres læge undersøge Dem for prostatakræft, før De begynder behandlingen med Urorec.
Since a benign enlargement of the prostate and prostate cancer may present the same symptoms, your doctor will check you for prostate cancer before starting treatment with Urorec.
Da en indirekte interaktion mellem komponenter i den orale kontraception og pegaspargase ikke kan udelukkes, anses oralt administrerede kontraceptiva ikke for tilstrækkeligt sikre i disse kliniske situationer (se pkt.
Since an indirect interaction between components of the oral contraception and pegaspargase cannot be ruled out, oral contraceptives are not considered sufficiently safe in such clinical situation (see sections 4.5 and 4.6).
Da en indirekte interaktion mellem komponenter i den orale kontraception og pegaspargase ikke kan udelukkes, anses oralt administrerede kontraceptiva ikke for tilstrækkeligt sikre i disse kliniske situationer.
Since an indirect interaction between components of the oral contraception and pegaspargase cannot be ruled out , oral contraceptives are not considered sufficiently safe in such clinical situation.
Da en sådan behandling kan føre til additiv og endda synergistisk toksicitet (f.eks. hepato- eller hæmatotoksicitet), er kombination med andre DMARD’er (f.eks. methotrexat) ikke tilrådelig.
Since such therapy can lead to additive or even synergistic toxicity (e.g. hepato- or haematotoxicity), combination with another DMARD (e.g. methotrexate) is not advisable.
Da en sådan behandling kan føre til additiv og endda synergistisk toksicitet (f.eks. hepato- eller hæmatotoksicitet), er kombination med andre DMARD’s (f.eks. methotrexat) ikke tilrådelig.
Since such therapy can lead to additive or even synergistic toxicity (e.g. hepato- or haematotoxicity), combination with another DMARD (e.g. methotrexate) is not advisable.
Da en sådan behandling kan føre til additiv og endda synergistisk toksicitet (f.eks. hepato- eller hæmatotoksicitet), er kombination med andre DMARD’s (f.eks. methotrexate) ikke tilrådelig.
Since such therapy can lead to additive or even synergistic toxicity (e.g. hepato- or haematotoxicity), combination with another DMARD (e.g. methotrexate) is not advisable.
Da en vurdering af post-marketing sikkerhedsdatabasen for Caelyx hos patienter ikke har tydet på en signifikant tilbøjelighed til nefrotoksicitet ved Caelyx, vil disse fund hos aber måske ikke have relevans for vurdering af patientrisiko.
Since an evaluation of the post-marketing safety database for Caelyx in patients has not suggested a significant nephrotoxicity liability of Caelyx, these findings in monkeys may not have relevance to patient risk assessment.
Da Entacapone Teva er et generisk lægemiddel, som er bioækvivalent med referencelægemidlet, anses benefit/risk-forholdet for at være det samme som for referencelægemidlet.
Because Entacapone Teva is a generic medicine and is bioequivalent to the reference medicine, its benefits and risks are taken as being the same as the reference medicine’s.
Da Enyglid er et generisk lægemiddel, som er bioækvivalent med referencelægemidlet, anses benefit/risk-forholdet for at være det samme som for referencelægemidlet.
Because Enyglid is a generic medicine and is bioequivalent to the reference medicine, its benefit and risk are taken as being the same as the reference medicine’s.
Da Eptifibatid Accord hæmmer trombocytaggregationen, skal der udvises forsigtighed, når det anvendes med andre stoffer, der påvirker hæmostasen, inklusive ticlopidin, clopidogrel, trombolytika, orale antikoagulantia, dextranopløsninger, adenosin, sulfinpyrazon, prostacyclin, non-steroide antiinflammatoriske stoffer eller dipyramidol (se pkt.
Because Eptifibatide Accord inhibits platelet aggregation, caution must be employed when it is used with other medicinal products that affect haemostasis, including ticlopidine, clopidogrel, thrombolytics, oral anticoagulants, dextran solutions, adenosine, sulfinpyrazone, prostacyclin, non- steroidal anti-inflammatory agents, or dypyridamole (see section 4.5).
Da Eptifibatid Accord hæmmer trombocytaggregationen, skal der udvises forsigtighed, når det anvendes med andre stoffer, der påvirker hæmostasen, inklusive ticlopidin, clopidogrel, trombolytika, orale antikoagulantia, dextranopløsninger, adenosin, sulfinpyrazon, prostacyclin, non-steroide antiinflammatoriske stoffer, eller dipyramidol (se pkt.
Because Eptifibatide Accord inhibits platelet aggregation, caution must be employed when it is used with other medicinal products that affect haemostasis, including ticlopidine, clopidogrel, thrombolytics, oral anticoagulants, dextran solutions, adenosine, sulfinpyrazone, prostacyclin, non- steroidal anti-inflammatory agents, or dypyridamole (see section 4.5).
Da Eptifibatide Accord er et generisk lægemiddel, antages det at have de samme fordele og risici som referencelægemidlet.
Because Eptifibatide Accord is a generic medicine, its benefits and risks are taken as being the same as the reference medicine’s.
Da esomeprazol er en enantiomer af omeprazol, er det hensigtsmæssigt at oplyse om interaktioner, som er rapporteret med omeprazol.
As esomeprazole is one enantiomer of omeprazole it is reasonable to advise about interactions reported with omeprazole.
Da et IgM-respons efter vaccination er ualmindeligt, vil en positiv IGM-ELISA test være en stærk indikator for en naturlig infektion med West Nile virus.
However, since the IgM response following vaccination is infrequent, a positive IgM-ELISA test result is a strong indicator of natural infection with West Nile Virus.
Da Eucreas indeholder metformin, skal behandlingen seponeres 48 timer før elektiv operation med helbedøvelse og må normalt først genoptages tidligst 48 timer efter operationen.
As Eucreas contains metformin, the treatment should be discontinued 48 hours before elective surgery with general anaesthesia and should not usually be resumed earlier than 48 hours afterwards.
Da eventuelle leverskader forvoldt af alkohol kan forværres af behandling med Leflunomide Teva,
Drinking alcohol while taking Leflunomide Teva may increase the chance of liver damage.
Da Eviplera er et kombinationspræparat, og doseringsintervallet for de enkelte komponenter ikke kan ændres, skal behandlingen med Eviplera afbrydes hos patienter med bekræftet kreatininclearance på under < 50 ml/min eller fald i serumphosphat til < 1,0 mg/dl (0,32 mmol/l).
Since Eviplera is a combination product and the dosing interval of the individual components cannot be altered, treatment with Eviplera must be interrupted in patients with confirmed creatinine clearance decreased to < 50 mL/min or decreases in serum phosphate to < 1.0 mg/dL (0.32 mmol/L).
Da Eviplera indeholder emtricitabin, rilpivirinhydrochlorid og tenofovirdisoproxilfumarat, kan interaktioner, som er identificeret med disse aktive stoffer individuelt, forekomme med Eviplera.
As Eviplera contains emtricitabine, rilpivirine hydrochloride and tenofovir disoproxil fumarate, any interactions that have been identified with these active substances individually may occur with Eviplera.
Da Eylea er et proteinbaseret terapeutisk middel, er der ikke udført metabolismestudier.
As Eylea is a protein-based therapeutic, no metabolism studies have been conducted.
Da faktor VIII-produkter måske skal indgives oftere til børn, kan det være nødvendigt at anlægge et centralt venekateter (CVK); dette er en ekstern forbindelse, der giver adgang til blodbanen gennem et kateter, uden at der skal injiceres gennem huden.
Because factor VIII products may have to be given more often in children, a central venous access device (CVAD, an external connector allowing access to the bloodstream through a catheter without injection through the skin) may need to be fitted.
Da farmakokinetikken for 6–mercaptopurin ikke er formelt undersøgt ved leverinsufficiens, kan der ikke gives nogen specifikke dosisanbefalinger.
Since 6–mercaptopurine pharmacokinetics has not been formally studied in hepatic impairment, no specific dose recommendations can be given.
Da farmakokinetikken for 6–mercaptopurin ikke er formelt undersøgt ved nyreinsufficiens, kan der ikke gives nogen specifikke dosisanbefalinger.
Since 6–mercaptopurine pharmacokinetics has not been formally studied in renal impairment, no specific dose recommendations can be given.
Da farmakologisk aktive metabolitter udskilles via urinen, anbefales det dog, at patienter med svært nedsat nyrefunktion overvåges omhyggeligt for alle bivirkninger.
However, considering that pharmacologically active metabolites are eliminated via urine, it is advised that patients with severe renal impairment should be carefully monitored for any adverse reactions.
Da firmaet har fremlagt de supplerende oplysninger, der var anmodet om, ophørte markedsføringstilladelsen med at være ”under særlige omstændigheder” den 28. juli 2006.
As the company had supplied the additional information requested, the ’Exceptional Circumstances’ ended on 28 July 2006.
Da fluoxetin har samme metaboliske profil som paroxetin, dvs. en stærk CYP2D6-hæmmende effekt, kan en lignende mangel på interaktion forventes for fluoxetin.
Since fluoxetine shares a similar metabolic profile with paroxetine, i.e. a strong CYP2D6 inhibitory effect, a similar lack of interaction would be expected for fluoxetine.
Da foderindtagelsen er reduceret som hvis der bruges en traditionel ikke-medicinsk lavenergimetode, må man under behandlingen sikre, at protein, vitaminer, essentielle fede syrer og mineraler, som indtages i den daglige foderration, indeholder minimum det anbefalede behov, for at sikre en komplet og ernæringsmæssigt afbalanceret ernæring.
In the treatment phase, because food intake is reduced as when using a traditional non-medical calorie restriction method, care must be taken to ensure that protein, vitamins, essential fatty acids and minerals supplied by the consumed daily food ration meet minimal recommended requirements in order to ensure a complete and balanced nutritional supply.
Da fordelen observeret hos patienter med 4+lymfeknuder ikke var statistisk signifikant for DFS og OS, blev den positive benefit/risk fordeling for TAC hos patienter med 4+lymfeknuder ikke helt demonstreret ved den endelige analyse.
As the benefit observed in patients with 4+ nodes was not statistically significant on DFS and OS, the positive benefit/risk ratio for TAC patients with 4+ nodes was not fully demonstrated at the final analysis.
Da fordelene hos patienter med 4+ lymfeknuder ikke var statistisk signifikante for sygdoms- fri overlevelse (DFS) og total overlevelse (OS), blev det positive. fordel/risiko forhold for TAC- patienter med 4+ lymfeknuder ikke fuldt demonstreret i den endelige analyse . (se pkt.
As the benefit observed in patient with 4+ nodes was not statistically significant on disease-free survival (DFS) and overall survival (OS), the positive benefit/risk ratio for TAC in patients with 4+ nodes was not fully demonstrated at the final analysis (see section 5.1).
Da fordelene hos patienter med 4+ lymfeknuder ikke var statistisk signifikante for sygdoms-fri overlevelse (DFS) og total overlevelse (OS), blev det positive fordel/risiko forhold for TAC-patienter med 4+ lymfeknuder ikke fuldt demonstreret i den endelige analyse. (se pkt.
As the benefit observed in patient with 4+ nodes was not statistically significant on disease-free survival (DFS) and overall survival (OS), the positive benefit/risk ratio for TAC in patients with 4+ nodes was not fully demonstrated at the final analysis (see section 5.1).
Da fordelene hos patienter med 4+ lymfeknuder ikke var statistisk signifikante for sygdoms-fri overlevelse (DFS) og total overlevelse (OS), blev det positive fordel/risiko-forhold for TAC-patienter med 4+ lymfeknuder ikke fuldt demonstreret i den endelige analyse. (se pkt.
As the benefit observed in patient with 4+ nodes was not statistically significant on disease-free survival (DFS) and overall survival (OS), the positive benefit/risk ratio for TAC in patients with 4+ nodes was not fully demonstrated at the final analysis (see section 5.1).
Da fordelene ved vaccination er stor for denne gruppe børn, bør vaccination ikke udelades eller forsinkes.
As the benefit of the vaccination is high in this group of infants, vaccination should not be withheld or delayed.
Da fordelene ved vaccination er stor for denne gruppe børn, bør vaccination ikke udelades eller forsinkes.
As the benefit of vaccination is high in this group of infants, vaccination should not be withheld or delayed.
Da fordelene ved vaccination er store for denne gruppe af nyfødte, skal vaccination ikke tilbageholdes eller forsinkes.
As the benefit of vaccination is high in this group of infants, vaccination should not be withheld or delayed.
Da fordelenet hos patienter med 4+lymfeknuder ikke var statistisk signifikant for DFS og OS, blev den positive benefit/risk fordeling for TAC hos patienter med 4+lymfeknuder ikke helt demonstreret ved den endelige analyse.
As the benefit observed in patients with 4+ nodes was not statistically significant on DFS and OS, the positive benefit/risk ratio for TAC in patients with 4+ nodes was not fully demonstrated at the final analysis.
Da forløbet skal overvåges i dagene efter injektionen, og da der er risiko for nedsat syn i det øje, hvor injektionen blev givet, anbefales det ikke at behandle det andet øje med Jetrea samtidigt med eller inden for 7 dage efter den indledende injektion.
Treatment with JETREA in the other eye is not recommended concurrently or within 7 days of the initial injection in order to monitor the post-injection course including the potential for decreased vision in the injected eye.
Da formuleringerne ikke er bioækvivalente, bør hverken granulatet til oral suspension eller tyggetabletterne erstatte 400 mg tabletten (se pkt.
Because the formulations are not bioequivalent, neither the granules for oral suspension nor the chewable tablets should be substituted for the 400 mg tablet (see section 5.2).
Da formuleringerne ikke er bioækvivalente, bør hverken tyggetabletterne eller granulatet til oral suspension erstatte 400 mg tabletten (se pkt.
Because the formulations are not bioequivalent, neither the chewable tablets nor the granules for oral suspension should be substituted for the 400 mg tablet (see section 5.2).
Da forøgelser af denne størrelse ikke er klinisk relevante, anbefales dosisjustering ikke til patienter med let nedsat nyrefunktion.
Because increases of this magnitude are not clinically relevant, dose adjustment in patients with mild renal impairment is not recommended.
da g 1
Day 1
da g 2
Day 2
da g 22
Day 22
da g 3
Day 3
Da gastrointestinal perforation er en væsentlig klinisk hændelse, der kan føre til en alvorlig eller livstruende tilstand, bør passende behandling overvejes umiddelbart efter mistænkte symptomer eller tegn opstår.
As gastrointestinal perforation is a medically important event that may lead to a life-threatening or serious condition, adequate treatments should be considered immediately after suspected symptoms or signs occur.
Da GC-C (guanylatcyclase C) receptor vides at være overudtrykt i en tidlig alder, kan børn under 2 år være særligt følsomme over for virkninger af linaclotid.
As GC- C receptor is known to be overexpressed at early ages, children younger than 2 years may be particularly sensitive to linaclotide effects.
Da generiske lægemidler svarende til Zoledronsyre Teva er generiske lægemidler, antages de at have de samme fordele og risici som referencelægemidlet.
Because Zoledronic acid Teva Generics is a generic medicine, its benefits and risks are taken as being the same as the reference medicine’s.
Da Gilenya nedsætter hjertefrekvensen, bør lægen kontrollere patientens blodtryk og hjertefrekvens samt tage et elektrokardiogram (EKG, en test, hvor hjertets elektriske aktivitet måles), inden den første dosis gives.
Because Gilenya decreases the heart rate, doctors should check the patient’s blood pressure, heart rate, as well as their heart by electrocardiogram (ECG, a test that measures the electrical activity of the heart) before giving the first dose.
Da Glidipion er et generisk lægemiddel, som er bioækvivalent med referencelægemidlet, anses benefit/risk-forholdet for at være det samme som for referencelægemidlet.
Because Glidipion is a generic medicine and is bioequivalent to the reference medicine, its benefits and risks are taken as being the same as the reference medicine’s.
Da glukokortikoider kan forårsage forringet vækst, bør anvendelse til unge dyr i vækst overvåges nøje, og store læsioner bør ikke behandles
Since glucocorticosteroids can slow growth, use in young, growing animals should be well controlled and large lesions should not be treated.
Da godkendelsen for Tagrisso er betinget, skal den virksomhed, der markedsfører Tagrisso, forelægge resultaterne af en undersøgelse, hvor Tagrisso sammenlignes med platinbaseret kemoterapi (standardbehandlingen for ikke-småcellet lungekræft).
Since Tagrisso has been granted a conditional approval, the company that markets Tagrisso will provide the findings of a study comparing Tagrisso with platinum-based chemotherapy (standard treatment for NSCLC).
Da granisetron metaboliseres af hepatisk cytokrom P450 lægemiddelmetaboliserende enzymer (CYP1A1 og CYP3A4), kan inducere eller hæmmere af disse enzymer ændre clearance og dermed granisetrons halveringstid.
As granisetron is metabolised by hepatic cytochrome P450 drug-metabolising enzymes (CYP1A1 and CYP3A4), inducers or inhibitors of these enzymes may change the clearance and, hence, the half-life of granisetron.
Da hepatitis B-virusset kan blive resistent over for Hepsera, bør lægen kun ordinere Hepsera, hvis der ikke kan anvendes andre behandlinger, som giver mindre risiko for udvikling af resistens, dekompenseret leversygdom (hvor leveren er beskadiget og ikke fungerer normalt).
Because the hepatitis B virus can become resistant to Hepsera, the doctor should only consider prescribing Hepsera if other treatments that are less likely to lead to resistance cannot be used; decompensated liver disease (when the liver is damaged and does not function normally.
Da Herceptin i injektionssystem er fastgjort til kroppen med en klæbepude, bør Herceptin 600 mg injektionsvæske i hætteglas overvejes til patienter, der vides at være overfølsommehed over for lim (akryl 562).
Herceptin in administration system is affixed to the body with an adhesive pad, therefore for patients with known hypersensitivity to adhesive (Type Acrylic 562), the Herceptin 600 mg Solution for injection in vial should be considered as an alternative.
Da homocystinuri er sjælden, blev Cystadane udpeget som "lægemiddel til sjældne sygdomme" den 9. juli 2001.
Because the number of patients with homocystinuria is low, the disease is considered ‘rare’, and Cystadane was designated an ‘orphan medicine’ (a medicine used in rare diseases) on 9 July 2001.
Da hormonel prævention muligvis ikke er effektiv under behandling med Tracleer, og også på grund af risikoen for at pulmonal hypertension forværres alvorligt under graviditet, anbefales det, at der udføres månedlige graviditetsprøver under Tracleerbehandlingen for at opdage en graviditet tidligst muligt.
Because of possible hormonal contraception failure during Tracleer treatment, and also bearing in mind the risk that pulmonary hypertension severely deteriorates with pregnancy, monthly pregnancy tests during treatment with Tracleer are recommended to allow early detection of pregnancy.