natgillin/translations-raw huggingface dataset:
I normale donorer er dyspnø almindeligt rapporteret og andre pulmonale bivirkninger (hæmoptyse, pulmonal blødning, lunge infiltrater og hypoxi) er blevet rapporteret sjældent.
In normal donors, dyspnoea has been reported commonly and other pulmonary adverse events (haemoptysis, pulmonary haemorrhage, lung infiltrates, and hypoxia) have been reported uncommonly.
I normale donorer er dyspnø almindeligt rapporteret og andre pulmonale bivirkninger (hæmoptyse, pulmonal blødning, lunge infiltrater og hypoxia) er blevet rapporteret sjældent.
In normal donors, dyspnoea has been reported commonly and other pulmonary adverse events (haemoptysis, pulmonary haemorrhage, lung infiltrates, and hypoxia) have been reported uncommonly.
I normale donorer er dyspnø almindeligt rapporteret og andre pulmonale bivirkninger (hæmoptyse, pulmonal blødning, lungeinfiltrater og hypoxia) er blevet rapporteret sjældent.
In normal donors, dyspnoea has been reported commonly and other pulmonary adverse events (haemoptysis, pulmonary haemorrhage, lung infiltrates, and hypoxia) have been reported uncommonly.
I NSABP B-31 og NCCTG N9831-studierne blev Herceptin administreret i kombination med paclitaxel efter AC-kemoterapi.
In the NSABP B-31 and NCCTG N9831 studies Herceptin was administered in combination with paclitaxel, following AC chemotherapy.
I NSABP B-31 ogNCCTG N9831-studierne blev Herceptin administreret i kombination med paclitaxel efter AC-kemoterapi.
In the NSABP B-31 and NCCTG N9831 studies Herceptin was administered in combination with paclitaxel, following AC chemotherapy.
I nuværende klinisk praksis måles koncentrationer i fuldblod med immunoassay- metoder.
In current clinical practice, whole blood levels are monitored using immunoassay methods.
I nuværende kliniske praksis bliver koncentrationen af sirolimus i fuldblod målt ved både kro- matografiske og immunologiske metoder.
Currently in clinical practice, sirolimus whole blood concentrations are being measured by both chromatographic and immunoassay methodologies.
I nuværende kliniske praksis, bliver koncentrationen af sirolimus i fuldblod målt ved både kro- matografiske og immunologiske metoder.
Currently in clinical practice, sirolimus whole blood concentrations are being measured by both chromatographic and immunoassay methodologies.
I NV17424 (PEDS-C) studiet blev tidligere ubehandlede pædiatriske patienter fra 5 til 17 år (55 %
In the NV17424 (PEDS-C) study, previously untreated paediatric patients 5 to 17 years of age (55
I NVAF-studierne var den samlede bivirkningsfrekvens relateret til blødning pga. apixaban 24,3% i apixaban versus warfarin studiet og 9,6% i apixaban- versus acetylsalicylsyrestudiet.
In the NVAF studies, the overall incidence of adverse reactions related to bleeding with apixaban was 24.3% in the apixaban vs warfarin study and 9.6% in the apixaban vs acetylsalicylic acid study.
I NVAF-studierne var den samlede bivirkningsfrekvens relateret til blødning pga. apixaban 24,3% i apixaban- versus warfarinstudiet og 9,6% i apixaban- versus acetylsalicylsyrestudiet.
In the NVAF studies, the overall incidence of adverse reactions related to bleeding with apixaban was 24.3% in the apixaban vs warfarin study and 9.6% in the apixaban vs acetylsalicylic acid study.
I nyfødte kalve:
In new born calves:
I nyrerne inhiberer spironolaktone den aldosteron-inducerede natriumretention, hvilket fører til en øget udskillelse af natrium og vand, samt retention af kalium.
In the kidney, spironolactone inhibits the aldosterone-induced sodium retention leading to increase in sodium and subsequently water excretion, and potassium retention.
I nyretransplantationsstudierne med belatacept blev der rapporteret om en patient, der fik samtidig behandling med en IL-2- receptorantagonist, mycophenolatmofetil (MMF) og kortikosteroider.
In the renal transplant studies of belatacept, one case of PML was reported in a patient who received an IL-2 receptor antagonist, mycophenolate mofetil (MMF) and corticosteroids as concomitant treatment.
I nødstilfælde hos aktuelle Actrapid brugere (hospitaliserede eller ved defekt insulinpen) kan Actrapid udtages med en 100 E insulinsprøjte fra en cylinderampul.
In case of emergency in current Actrapid users (hospitalisation or insulin pen malfunction), Actrapid can be withdrawn with an U100 insulin syringe from a cartridge.
I nødstilfælde hos aktuelle Actrapid brugere (hospitaliserede eller ved defekt insulinpen) kan Actrapid udtages med en 100 E insulinsprøjte fra InnoLet.
In case of emergency in current Actrapid users (hospitalisation or insulin pen malfunction), Actrapid can be withdrawn with an U100 insulin syringe from InnoLet.
I nødstilfælde hos aktuelle Actrapid brugere (hospitaliserede eller ved defekt insulinpen), kan Actrapid udtages med en 100 E insulinsprøjte fra FlexPen.
In case of emergency in current Actrapid users (hospitalisation or insulin pen malfunction), Actrapid can be withdrawn with an U100 insulin syringe from FlexPen.
I nødstilfælde hos nuværende brugere af NovoRapid (grundet hospitalsindlæggelse eller insulin- pensvigt), kan NovoRapid trækkes ud med en insulinsprøjte på 100 enheder fra en NovoRapid cylinderampul eller fyldt pen.
In case of emergency in current NovoRapid users (hospitalisation or insulin pen malfunction), NovoRapid can be withdrawn with an U100 insulin syringe from a NovoRapid cartridge or pre-filled pen.
I observationsgruppen steg den mediane IgG-koncentration efterfølgende til over nedre referencegrænse, men forblev konstant i MabThera-gruppen.
In the observation group, the median IgG level subsequently increased to above the LLN, but remained constant in the MabThera group.
I og med at selexipag ikke påvirker eksponeringen for CYP3A4-substratet R-warfarin eller CYP2C9-substratet S-warfarin, forventes der ikke nedsat virkning af hormonelle kontraceptiva.
Since selexipag did not affect the exposure to the CYP3A4 substrate R-warfarin or to the CYP2C9 substrate S-warfarin, reduced efficacy of hormonal contraceptives is not expected.
I olaratumab plus doxorubicin-armen var de alvorligste (grad ≥ 3) bivirkninger neutropeni (54,7 %) og muskuloskeletale smerter (7,8 %).
In the olaratumab plus doxorubicin arm, the most serious (Grade ≥3) adverse drug reactions (ADRs) observed were neutropenia (54.7 %) and musculoskeletal pain (7.8 %).
I områder der er endemisk for hjerteorm, kan behandlinger en gang om måneden signifikant reducere risikoen for re-infektioner forårsaget af henholdsvis rund-, hage og piskeorm.
In areas endemic for heartworm, monthly treatment may significantly reduce the risk of re-infection caused by the respective round-, hook- and whipworms.
I områder der ikke er endemiske for hjerteorm, kan produktet bruges som en del af et sæsonbestemt forebyggende program mod lopper og gastrointestinale nematoder.
In areas non-endemic for heartworm, the product can be used as part of a seasonal prevention programme against fleas and gastrointestinal nematodes.
I områder hvor hjerteorm forekommer, kan behandlinger en gang om måneden mærkbart reducere risikoen for re-infektioner forårsaget af henholdsvis rund-, hage og piskeorm.
In areas endemic for heartworm, monthly treatment may significantly reduce the risk of re-infection caused by the respective roundworm, hookworms and whipworms.
I områder hvor hjerteorm forekommer, kan behandlinger en gang om måneden mærkbart reducere risikoen for re-infektioner forårsaget af henholdsvis rundorm og hageorm.
In areas endemic for heartworm, monthly treatment may significantly reduce the risk of re-infection caused by the respective roundworms and hookworms.
I områder hvor hjerteorm ikke forekommer, kan produktet bruges som en del af et sæsonforebyggende program mod lopper og indvoldsorme.
In areas non-endemic for heartworm, the product can be used as part of a seasonal prevention programme against fleas and gastrointestinal nematodes.
I områder, hvor der ikke forekommer smitte med hjerteorm, kan man give hundene en enkelt dosis af Trifexis for at forebygge sæsonbetingede loppeangreb, når der er
In areas where heartworm infection does not occur, dogs may be given a single dose of Trifexis to prevent seasonal fleas when infections with gut nematodes have been
I områder, hvor der vides at forekomme infektion med hjerteorm, bør den første dosis gives én måned før den forventede forekomst af myg og derefter med månedlige intervaller i den tid af året, hvor der forekommer myg og lopper, indtil mindst én måned efter sidste udsættelse for myg.
In areas where heartworm infection is known to occur, the first dose should be given one month before the expected appearance of mosquitoes and then at monthly intervals during the time of year when mosquitoes and fleas are present, until at least one month after the last exposure to mosquitoes.
I områder, hvor hepatitis B er almindeligt forekommende, bør der fortsat vaccineres mod hepatitis B ved fødslen, og vaccination med Tritanrix HepB kan indledes i seks-ugers-alderen.
In areas where hepatitis B is common, vaccination against hepatitis B at birth should be continued as normal, with Tritanrix HepB started at six weeks of age.
I Onivyde er irinotecan indkapslet i bittesmå fedtpartikler, der kaldes liposomer.
In Onivyde, irinotecan is contained within tiny fat particles called ‘liposomes’.
I op til en time efter indgift af lægemidlet kan vaskulære strukturer MRA- scannes med høj opløsning.
High resolution MRA scans of vascular structures are obtained up to one hour after administration of the medicinal product.
i opdelte doser i 2-5 dage kombineret med
in divided doses for 2-5 days in
I open-label perioderne i studie I, II, III og VI var forbedring i fysisk funktion opretholdt gennem henholdsvis 7 år, 5 år, 5 år og 2 år.
During the open-label periods of Studies I, II, III, and VI the improvement in physical function has been maintained through 7 years, 5 years, 5 years, and 2 years, respectively.
I opløsningsmidlet er indholdsstofferne mannitol og vand.
In the solvent the ingredients are mannitol and water.
I opløsningsmidlet: carmellosenatrium, natriumchlorid, polysorbat 20, natriumdihydrogenphosphat monohydrat, dinatriumphosphat-heptahydrat og vand til injektionsvæsker.
In the solvent: carmellose sodium, sodium chloride, polysorbate 20, sodium dihydrogen phosphate monohydrate, disodium phosphate heptahydrate and water for injection.
I opløsningsmidlet: carmellosenatrium, natriumchlorid, polysorbat 20, natriumdihydrogenphosphat monohydrat, dinatriumphosphat-heptahydrat, vand til injektionsvæsker og natriumhydroxid (til justering af pH-værdien (surhed)).
In the solvent: carmellose sodium, sodium chloride, polysorbate 20, sodium dihydrogen phosphate monohydrate, disodium phosphate heptahydrate, water for injection and sodium hydroxide (for pH adjustment).
I ordinationsvejledningen vil der være en tjekliste for at minde den ordinerende læge om kontraindikationer, advarsler og forsigtighedsregler før ordination og for at understøtte regelmæssig monitorering af kardiovaskulær risiko.
Within the prescriber guide there will be a check-list to remind prescribers of the contraindications, warnings and precautions prior to prescribing and to support the regular monitoring of cardiovascular risk.
I organismen omdannes 6-mercaptopurin i cellerne til et stof, der griber ind i dannelsen af nyt dna.
In the body, 6–mercaptopurine is converted within cells into a substance that interferes with the production of new DNA.
I osteoporose-behandlingsforsøget viste bazedoxifen 20 mg og raloxifen 60 mg efter 3 års behandling signifikante fald i det samlede kolesterolindhold i serum, lavdensitetslipoprotein (LDL)-kolesterol og en signifikant stigning i højdensitetslipoprotein (HDL)-kolesterol sammenlignet med placebo.
In the osteoporosis treatment study after 3 years of treatment, bazedoxifene 20 mg and raloxifene 60 mg exhibited significant reductions in serum total cholesterol, low-density lipoprotein (LDL) cholesterol and a significant increase in high-density lipoprotein (HDL) cholesterol compared to placebo.
I osteoporose-behandlingsstudiet med bazedoxifen (gennemsnitsalder = 66,5 år) var VTE-raten pr.
In the bazedoxifene osteoporosis treatment trial (mean age = 66.5 years), the VTE rate per
I osteoporosebehandlingsundersøgelsen blev endometrietykkelsen evalueret årligt i 4 år i en under- gruppe af undersøgelsespopulationen (1.644 patienter).
In the osteoporosis treatment trial, endometrial thickness was evaluated annually in a subset of the study population (1,644 patients) for 4 years.
I osteoporoseforsøget (PFT, HORIZON – Tilbagevendende Fraktur Studie [RFT] var den samlede incidens for atrieflimren sammenlignelig for Aclasta (2,6 %) og placebo (2,1 %).
In the osteoporosis trials (PFT, HORIZON - Recurrent Fracture Trial [RFT]) the pooled atrial fibrillation incidences were comparable between Aclasta (2.6%) and placebo (2.1%).
I osteoporoseforsøget (PFT, HORIZON – Tilbagevendende Fraktur Studie [RFT] var den samlede incidens for atrieflimren sammenlignelig for zoledronsyre (2,6 %) og placebo (2,1 %).
In the osteoporosis trials (PFT, HORIZON - Recurrent Fracture Trial [RFT]) the pooled atrial fibrillation incidences were comparable between zoledronic acid (2.6%) and placebo (2.1%).
I osteoporoseforsøget (PFT, HORIZON – Tilbagevendende Fraktur Studie [RFT] var den samlede incidens for atrieflimren sammenlignelig for zoledronsyre (2,6%) og placebo (2,1%).
In the osteoporosis trials (PFT, HORIZON - Recurrent Fracture Trial [RFT]) the pooled atrial fibrillation incidences were comparable between zoledronic acid (2.6%) and placebo (2.1%).
I otte offentliggjorte kliniske undersøgelser (8 fase III afprøvninger) omfattende 4735 patienter med fremskreden ovariekræft og i tolv offentliggjorte kliniske afprøvninger (én stor fase II og elve fase III afprøvninger) omfattende 4315 NSCLC patienter behandlet med paclitaxel og platin-indeholdende regimer, blev der observeret lignende bivirkninger sammenlignet med enkeltmiddel- paclitaxelbehandling.
In eight published clinical trials (8 Phase III trials) including 4,735 patients with advanced ovarian cancer and in twelve published clinical trials (one large Phase II and eleven Phase III trials) including 4,315 NSCLC patients treated with paclitaxel and platinum-containing regimens, similar undesirable effects were observed compared to single-agent paclitaxel treatment.
I otte studier, der er udført i forskellige europæiske lande samt i Chile og Filippinerne, er Synflorix’ immunogenicitet blevet vurderet efter primærvaccination med tre doser i overensstemmelse med de enkelte landes vaccinationsprogrammer (ved 6-10-14-ugers alderen, ved 2-3-4-, 3-4-5- eller 2-4-6- måneders alderen).
In total eight studies, conducted in various countries across Europe, in Chile and in the Philippines, have evaluated the immunogenicity of Synflorix after a three-dose primary series (N=3,089) according to different vaccination schedules (6-10-14 weeks, 2-3-4, 3-4-5 or 2-4-6 months of age).
I ovenstående eksempel viser dosisantallet, at der er 13 injektioner tilbage.
In the example above the dose number shows there are 13 injections left
I ovenstående tilfælde bør en oral opløsning anvendes.
In all of the above cases an oral solution should be used.
I ovenstående tilfælde bør Levetiracetam ratiopharm 100 mg/ml oral opløsning anvendes.
In all of the above cases Levetiracetam ratiopharm 100 mg/ml oral solution should be used.
I overensstemmelse hermed er certolizumab pegol et antistof Fab’ fragment konjugeret med PEG for at forlænge den terminale plasmaeliminationshalveringstid for Fab’ til en værdi, som er sammenlignelig med det fuldstændige antistof.
Accordingly, certolizumab pegol is an antibody Fab' fragment conjugated with PEG in order to extend the terminal plasma elimination half-life of the Fab' to a value comparable with a whole antibody product.
I overensstemmelse med CHMP-retningslinjerne for risikostyringsprogrammer for lægemidler til humant brug skal en opdateret RMP fremsendes samtidig med den efterfølgende periodiske sikkerhedsopdateringsrapport (PSUR).
As per the CHMP Guideline on Risk Management Systems for medicinal products for human use, the updated RMP should be submitted at the same time as the next Periodic Safety Update Report (PSUR).
I overensstemmelse med CHMP-retningslinjerne for risikostyringsprogrammer for lægemidler til men- nesker skal den opdaterede RMP fremsendes samtidig med den næste periodiske sikkerhedsopdate- ringsrapport (PSUR).
As per the CHMP Guideline on Risk Management Systems for medicinal products for human use, the updated RMP should be submitted at the same time as the next Periodic Safety Update Report (PSUR).
I overensstemmelse med CHMP-retningslinjerne for risikostyringsprogrammer for lægemidler til mennesker skal den opdaterede RMP fremsendes samtidig med den næste periodiske sikkerhedsopdateringsrapport (PSUR) (dvs. i den præ-pandemiske periode).
As per the CHMP Guideline on Risk Management Systems for medicinal products for human use, the updated RMP should be submitted at the same time as the next Periodic Safety Update Report (PSUR) (i.e. in the pre-pandemic period).
I overensstemmelse med de potentielt immunogene egenskaber ved lægemidler, der indeholder proteiner eller peptider, kan patienterne udvikle anti-lixisenatid antistoffer efter behandling med Lyxumia, og i slutningen af den 24-ugers behandlingsperiode i de placebokontrollerede studier havde 69,8 % af lixisenatid-patienterne en positiv antistofstatus.
Consistent with the potentially immunogenic properties of medicinal products containing proteins or peptides, patients may develop anti-lixisenatide antibodies following treatment with Lyxumia and, at the end of the main 24-week treatment period in placebo-controlled studies, 69.8% of lixisenatide patients had a positive antibody status.
I overensstemmelse med de virkninger, der er set ved andre stoffer, som binder til benzodiazepin- receptorer, blev reversibel øget vægt af lever og binyrer i rotter og hunde, kun observeret i forbindelse med gentagen oral administration af doser mange gange højere end den maksimale anbefalede humane dosis.
In line with effects observed with other compounds binding to benzodiazepine receptors, reversible increases in liver and adrenal weights in rats and dogs were only noted upon repeated oral administration of high multiples of the maximum human therapeutic dose.
I overensstemmelse med den udtalte proteinbinding har A771726 et lille fordelingsvolumen (ca.
Consistent with extensive protein binding A771726 has a low apparent volume of distribution (approximately
I overensstemmelse med dets antikolinerge aktivitet skal aclidiniumbromid anvendes med forsigtighed hos patienter med symptomatisk prostatahyperplasi eller blærehalsobstruktion eller med snævervinklet glaukom (omend direkte kontakt af produktet med øjnene er yderst usandsynligt).
Consistent with its anticholinergic activity, aclidinium bromide should be used with caution in patients with symptomatic prostatic hyperplasia or bladder-neck obstruction or with narrow-angle glaucoma (even though direct contact of the product with the eyes is very unlikely).
I overensstemmelse med disse data er der ikke rapporteret nogen klinisk relevante lægemiddelinteraktioner i kliniske studier med SANCUSO.
In agreement with these data, no clinically relevant drug interactions have been reported in clinical studies with SANCUSO.
I overensstemmelse med en begrænset ekstravaskulær fordeling er det gennemsnitlige fordelingsvolumen for pembrolizumab ved steady state lille (~7,4 liter; variationskoefficient (CV) 19%).
Consistent with a limited extravascular distribution, the volume of distribution of pembrolizumab at steady state is small (~7.4 L; CV: 19%).
I overensstemmelse med en selvregulerende clearancemekanisme falder serumkoncentrationen af lipegfilgrastim langsomt under kemoterapi-induceret forbigående neutrofil- nadir, og hurtigt under den følgende forbedring af neutrofiltallet (se figur 1).
Consistent with a self-regulating clearance mechanism, the serum concentration of lipegfilgrastim declines slowly during the chemotherapy-induced transient neutrophil nadir and rapidly at the following onset of neutrophil recovery (see figure 1).
I overensstemmelse med god avlspraksis bør de inficerede fugles omgivelser desuden rengøres og desinficeres med et egnet antimykotisk produkt.
In accordance with good animal husbandry, the cleaning and disinfection of the infected birds’ environment with an appropriate antifungal product should be recommended.
I overensstemmelse med god avlspraksis bør de inficerede fugles omgivelser desuden rengøres og desinficeres med et egnet svampemiddel.
In accordance with good animal husbandry, the cleaning and disinfection of the infected birds’ environment with an appropriate antifungal product is recommended.
I overensstemmelse med individuel klinisk vurdering anbefales det dog alligevel at kontrollere nyrefunktionen, serum-calcium, phosphat og magnesium hos patienter i Bondronat- behandling.
Nevertheless, according to clinical assessment of the individual patient, it is recommended that renal function, serum calcium, phosphate and magnesium should be monitored in patients treated with Bondronat.
I overensstemmelse med individuel klinisk vurdering anbefales det dog alligevel at kontrollere nyrefunktionen, serum-calcium, phosphat og magnesium hos patienter i Iasibon-behandling.
Nevertheless, according to clinical assessment of the individual patient, it is recommended that renal function, serum calcium, phosphate and magnesium should be monitored in patients treated with Iasibon.
I overensstemmelse med reduktion i føtal vækst blev der yderligere, sekundært til oligohydramnios, også noteret lungehypoplasi (1 af 6 i 30 mg/kg og 1 af 2 i 100 mg/kg gruppen), ventrikel-septum-defekt (1 af 6 i 30 mg/kg gruppen), tynd ventrikelvæg (1 af 2 i 100 mg/kg gruppen) og mindre skeletale misdannelser (eksterne – 3 af 6 i 30 mg/kg gruppen).
In addition, consistent with foetal growth restrictions, secondary to oligohydramnios, lung hypoplasia (1 of 6 in 30 mg/kg and 1 of 2 in100 mg/kg groups), ventricular septal defects (1 of 6 in 30 mg/kg group), thin ventricular wall (1 of 2 in 100 mg/kg group) and minor skeletal defects (external - 3 of 6 in 30 mg/kg group) were also noted.
I overensstemmelse med standard medicinsk praksis for indgivelse af hepatitis B-vaccine, skal der udføres regelmæssige antistofundersøgelser på hæmodialysepatienter.
In accordance with standard medical practice for hepatitis B vaccine administration, regular antibody testing should be done in hemodialysis patients.
I overensstemmelse med tidligere erfaringer var titre og persistens af antistofrespons generelt lave og forøgedes ikke ved forsat behandling (6,8% af forsøgspersonerne var seropositive ved 2 på hinanden følgende kontrolbesøg), og der var ingen åbenlys sammenhæng mellem udvikling af antistoffer og klinisk respons, bivirkninger eller farmakokinetik.
Consistent with previous experience, titers and persistence of antibody responses were generally low and did not increase upon continued dosing (6.8% subjects were seropositive on 2 consecutive visits), and there was no apparent correlation of antibody development to clinical response, adverse events, or PK.
I overensstemmelse med virkningsmekanisme reducerer rosiglitazon i kombination med metformin insulinresistens og forbedret pankreatisk -celle.
Consistent with the mechanism of action, rosiglitazone in combination with metformin reduced insulin resistance and improved pancreatic ß-cell function.
I overensstemmelse med virkningsmekanismen reducerede rosiglitazon insulinresistens og forbedrede pankreatisk -celle funktion.
Consistent with the mechanism of action, rosiglitazone reduced insulin resistance and improved pancreatic ß-cell function.