natgillin/translations-raw huggingface dataset:
Selvom PD-L1-status er prædiktiv for respons hos patienter med fremskredent melanom, er der observeret varig respons hos PD-L1-negative patienter.
Although PD-L1 status is predictive of response in advanced melanoma patients, durable responses have been observed in PD-L1 negative patients.
Selvom placebokontrollerede, pivotale fase III-studier med Jetrea viste fordele i form af en lukning af maculahuller, som er forbundet med vitreomaculær traktion, er der i nogle tilfælde blevet observeret øget traktion med efterfølgende progression eller opståen af et nyt maculahul.
Although in placebo-controlled pivotal phase III studies, JETREA has shown benefit in inducing closure of macular holes associated with vitreomacular traction, in some instances increased traction with subsequent progression or development of new macular hole has been observed.
Selvom pradofloxacin har in-vitro effekt på et bredt spektrum af Gram-positive og Gram-negative bakterier, inklusiv anaerobe bakterier, bør det kun bruges mod de godkendte indikationer (se afsnit 4.2) og i overensstemmelse med forsigtighedsreglerne i afsnit 4.5 i dette SPC.
Although pradofloxacin has in-vitro activity against a wide range of Gram-positive and Gram- negative organisms, including anaerobic bacteria, this veterinary medicinal product should only be used for the approved indications (see section 4.2) and in accordance with the prudent use recommendations in section 4.5 of this SPC.
Selvom proteinuri ( 2 g/dag) øgede belimumabs clearance, og et fald i kreatininclearance nedsatte belimumabs clearance, lå disse effekter inden for det forventede variabilitetsinterval.
Although proteinuria (> 2 g/day) increased belimumab clearance and decreases in creatinine clearance decreased belimumab clearance, these effects were within the expected range of variability.
Selvom prucaloprid kan være et svagt substrat for P-glykoprotein (P-gp), er det ikke en hæmmer af P- gp ved klinisk relevante koncentrationer.
Although prucalopride may be a weak substrate for P-glycoprotein (P-gp), it is not an inhibitor of P-gp at clinically relevant concentrations.
Selvom rilpivirin viste begrænset aktivitet in vitro mod hiv 2 med EC50-værdier i intervallet fra 2.510 til 10.830 nM (920 til
Although rilpivirine demonstrated limited in vitro activity against HIV-2 with EC50 values ranging from 2,510 to
Selvom risikoen for at personer med svækket immunforsvar bliver smittet med Bordetella bronchiseptica er ekstrem lille, anbefales det dog, at katte, der er i tæt kontakt med personer med svækket immunforsvar, ikke vaccineres med denne vaccine.
Although the risk of immunocompromised humans becoming infected with Bordetella bronchiseptica is extremely low, it is advised that cats, which are in close contact with immunocompromised humans are not vaccinated with this vaccine.
Selvom risikoen for knoglenekrose i kæben anses at være velkendt hos de ordinerende læger er der behov for yderligere opmærksomhed af en sådan risiko hos patienterne
In addition, although the risk for ONJ may be well known for the prescribers, further awareness on such risk is needed for the patients.
Selvom samtidig administration af OPV svagt kan nedsætte immunresponset overfor rotavirus-vaccine, blev den kliniske beskyttelse mod alvorlige typer rotavirus-gastroenteritis opretholdt i et klinisk studie med flere end 4.200 børn, som fik Rotarix samtidig med OPV.
Although concomitant administration of OPV may slightly reduce the immune response to rotavirus vaccine, clinical protection against severe rotavirus gastro-enteritis was shown to be maintained in a clinical trial involving more than 4200 subjects who received Rotarix concomitantly with OPV.
Selvom samtidig administration med CYP3A4 fremmere (f.eks. rifampicin, phenytoin, phenobarbital, carbamazepine, Hyperikum Perforatum) ikke er undersøgt, forventes det, at samtidig administration af potente CYP3A4 fremmere kan reducere plasmakoncentrationen af rimonabant og kan resultatere i tab af effekt.
Although concomitant administration of CYP3A4 inducers (e.g. rifampicin, phenytoin, phenobarbital, carbamazepine, St John’s wort) has not been studied, it is expected that concomitant administration of potent CYP3A4 inducers may reduce the plasma concentration of rimonabant and may result in loss of efficacy.
Selvom samtidig behandling med MTX resulterer i en højere steady-state-dalserumkoncentration af Simponi hos patienter med RA, PsA eller AS, indikerer data ikke, at der er behov for dosisjusteringer af hverken Simponi eller MTX (se pkt.
Although concomitant use of MTX results in higher steady-state trough concentrations of Simponi in patients with RA, PsA or AS, the data do not suggest the need for dose adjustment of either Simponi or MTX (see section 5.2).
Selvom sikkerhedsdata er begrænsede, kræves ingen særlige forholdsregler, når amphotericin B, itraconazol, nelfinavir eller mycophenolat mofetil administreres sammen med caspofungin.
Although safety data are limited it appears that no special precautions are needed when amphotericin B, itraconazole, nelfinavir or mycophenolate mofetil are co-administered with caspofungin.
Selvom sprøjten har denne sikkerhedsanordning, er det vigtigt, at sprøjterne efter brug bliver kasseret på den rigtige måde.
Although these syringes have this safety feature, it is still important that you dispose of used syringes properly.
Selvom studiet ikke havde styrke til at vise en statistisk signifikant forskel ved sammenligning af azacitidin med præselektions-CCR-behandlingsgrupperne, var overlevelsesfordelen ved Vidaza desuden længere ved sammenligning med CCR-behandlingsmulighederne BSC alene, lavdosis- cytarabin plus BSC, og den var sammenlignelig med standard intensiv kemoterapi plus BSC.
In addition, although the study was not powered to demonstrate a statistically significant difference when comparing azacitidine to the preselection CCR treatment groups, the survival of Vidaza treated patients was longer when compared to CCR treatment options BSC alone, low-dose cytarabine plus BSC and were similar when compared to standard intensive chemotherapy plus BSC.
Selvom større følsomhed for udvikling af bivirkninger ikke kan udelukkes hos nogle ældre patienter og asiatiske patienter, blev der ikke fundet nogen større forskel i sikkerhed og virkning mellem patienter over 65 år og yngre patienter eller mellem hvide patienter og patienter af andre racer.
Although greater sensitivity to develop adverse reactions in some older patients and Asian patients cannot be ruled out, overall, no major differences were observed in the safety and effectiveness of axitinib between patients who were ≥ 65 years of age and non-elderly, and between White patients and patients of other races.
Selvom sunitinib og den primære metabolit ikke elimineres ved hæmodialyse, var den systemiske eksponering for sunitinib 47% lavere og for den primære metabolit 31% lavere hos patienter med nyresygdom i slutstadiet sammenlignet med personer med normal nyrefunktion.
Although sunitinib and its primary metabolite were not eliminated through hemodialysis in subjects with ESRD, the total systemic exposures were lower by 47% for sunitinib and 31% for its primary metabolite compared to subjects with normal renal function.
Selvom TNF-hæmmere ikke påvirkede abatacepts clearance i placebo-kontrollerede forsøg, oplevede den patientgruppe, der fik samtidig behandling med abatacept og TNF-hæmmere, flere infektioner og alvorlige infektioner end de patienter, der fik behandling med TNF-hæmmere alene.
While TNF-inhibitors did not influence abatacept clearance, in placebo-controlled clinical trials, patients receiving concomitant treatment with abatacept and TNF-inhibitors experienced more infections and serious infections than patients treated with only TNF-inhibitors.
Selvom tramatinib- eksponering sandsynligvis ikke påvirkes af hæmning af BSEP, kan forhøjede trametinib-niveauer ikke udelukkes ved stærk hæmning af P-gp (se pkt.
Although trametinib exposure is unlikely to be affected by inhibition of BSEP, increased levels of trametinib upon strong inhibition of hepatic P-gp cannot be excluded (see section 4.5).
Selvom udvalget bemærkede, at brugen af Telzir forstærket med ritonavir er ikke undersøgt tilstrækkeligt hos patienter, der tidligere har fået omfattende behandling, og at der ingen sammenlignende undersøgelser var blevet gennemført hos børn, fandt udvalget, at fordelene ved Telzir opvejer risiciene, og anbefalede udstedelse af markedsføringstilladelse.
Although the Committee noted that the use of ritonavir-boosted Telzir had not been studied sufficiently in heavily pretreated patients and that no comparative studies had been carried out in children, it decided that Telzir’s benefits are greater than its risks and recommended that it be given marketing authorisation.
Selvom undergrupperne var små gav MabThera vedligeholdelsesbehandling en signifikant fordel i form af samlet overlevelse både for patienter, der responderede på CHOP og for patienter, der responderede på R-CHOP, dog er længere opfølgning nødvendig for at bekræfte denne observation.
Although subgroups were small, MabThera maintenance treatment provided a significant benefit in terms of overall survival for both patients responding to CHOP and patients responding to R-CHOP, although longer follow-up is required to confirm this observation.
Selvom undersøgelserne viste en lidt højere risiko for hjerteproblemer med Pradaxa end med warfarin, opvejede fordelene ved Pradaxa stadig opvejer risiciene.
Although the studies showed a small higher risk of heart problems with Pradaxa than with warfarin, the benefits of Pradaxa were still considered to outweigh its risks.
Selvom virkningen af hæmodialyse ved overdosering med Aripiprazole ikke er undersøgt, er det ikke sandsynligt, at hæmodialyse kan anvendes til behandling af overdosering, da Aripiprazole i udstrakt grad bindes til plasmaproteiner.
Although there is no information on the effect of haemodialysis in treating an overdose with aripiprazole, haemodialysis is unlikely to be useful in overdose management since aripiprazole is highly bound to plasma proteins.
Selvom YENTREVE ikke er godkendt til behandling af depression, bruges det aktive stof (duloxetin) også som en antidepressiv medicin.
Although YENTREVE is not indicated for the treatment of depression, its active ingredient (duloxetine) is used as an antidepressant medicine.
Selvom ændringerne i clarithromycin-parametre ikke anses for klinisk relevante, bør reduktionen af AUC for 14-OH- metabolitten tages med i overvejelserne ved behandling af infektioner forårsaget af Haemophilus influenzae, idet 14- OH-metabolitten er den mest aktive.
Whilst the changes in clarithromycin parameters are not considered clinically relevant, the reduction in the 14-OH metabolite AUC should be considered for the treatment of infections caused by Haemophilus influenzae in which the 14-OH metabolite is most
Selvom ændringerne i clarithromycin-parametre ikke anses for klinisk relevante, bør reduktionen af AUC for 14-OH- metabolitten tages med i overvejelserne ved behandling af infektioner forårsaget af Haemophilus influenzae, idet 14- OH-metabolitten er den mest aktive.
Whilst the changes in clarithromycin parameters are not considered clinically relevant, the reduction in the 14-OH metabolite AUC should be considered for the treatment of infections caused by Haemophilus influenzae in which the 14-OH metabolite is most active.
Selvom ætiologien anses for at være multifaktoriel (inklusive kortikosteroid anvendelse, alkoholforbrug, svær immunsuppression, højere BMI), er tilfælde af osteonekrose blevet observeret især blandt patienter med fremskreden hiv-sygdom og/eller langvarig eksponering for antiretroviral kombinationsbehandling.
Although the etiology is considered to be multifactorial (including corticosteroid use, alcohol consumption, severe immunosuppression, higher body mass index), cases of osteonecrosis have been reported particularly in patients with advanced HIV disease and/or long-term exposure to combination anti-retroviral therapy.
Semintra anvendes til at mindske proteinuri (øget mængde af protein i urinen).
Semintra is used to reduce proteinuria (protein in the urine).
Semintra blev sammenlignet med benazepril (et andet veterinærlægemiddel, som anvendes til at mindske proteinuri) i en undersøgelse i felten hos 224 katte, som hovedsaglig var over 11 år, og som havde kronisk nyresygdom.
Semintra was compared to benazepril (another medicine used in veterinary medicines to reduce proteinuria) in a field study involving 224 cats, aged mainly over 11 years, with chronic kidney disease.
Semintra er et lægemiddel, som indeholder det aktive stof telmisartan.
Semintra is a veterinary medicine that contains the active substance telmisartan.
Semintra mindskede mængden af protein i urinen inden for en uge, efter at behandlingen begyndte.
Semintra decreased protein in the urine within the first seven days after the start of treatment.
Semintra må ikke anvendes hos drægtige eller diegivende katte.
Semintra must not be given to pregnant or lactating cats.
Semintra var lige så effektivt som benazepril til at mindske proteinuri hos katte med kronisk nyresygdom.
Semintra was as effective as benazepril in reducing proteinuria in cats with chronic kidney disease.
Semintra, 4 mg/ml oral opløsning til katte
Semintra 4 mg/ml oral solution for cats
Semintra, 4 mg/ml oral opløsning til katte Telmisartan
Semintra 4 mg/ml oral solution for cats Telmisartan
Sen fase
Delayed phase
Sen fase†
Delayed phase
Sen neutropeni
Late neutropenia
sen strålingsreaktion. du for nylig er blevet vaccineret, da det muligvis kan forårsage dårlige virkninger med Pemetrexed medac.
you have had or are going to have radiation therapy, as there may be an early or late radiation reaction with Pemetrexed medac. you have been recently vaccinated, as this can possibly cause bad effects with Pemetrexed medac.
Seneforstyrrelser, der er forbundet med administration af fluorquinolon, i anamnesen.
History of tendon disorders related to fluoroquinolone administration.
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Humalog BASAL KwikPen). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog BASAL KwikPen (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog BASAL than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Humalog BASAL). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog BASAL (angivet i pu nkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog BASAL than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Humalog Kwikpen). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog KwikPen (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Humalog Mix25 KwikPen). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog Mix25 KwikPen (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog Mix25 than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Humalog Mix25). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog Mix25 (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog Mix25 than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Humalog Mix25). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog Mix25 (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog Mix25than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Humalog Mix50 KwikPen). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog Mix50 KwikPen (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog Mix50 than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Humalog Mix50). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog Mix50 (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog Mix50 than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Humalog). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Liporolog Basal KwikPen). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Liprolog Basal KwikPen (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Liprolog Basal than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Liprolog ).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see section 3: If you take more Liprolog than you need).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget liprolog Basal). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Liprolog Basal (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Liprolog Basal than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Liprolog KwikPen). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Liprolog KwikPen (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Liprolog than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: hvis du har taget for meget Liprolog Mix25 KwikPen). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Liprolog Mix25 KwikPen (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Liprolog Mix25 than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Liprolog Mix25). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Liprolog Mix25 (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Liprolog Mix25 than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Liprolog Mix50 Kwikpen). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Liprolog Mix50 KwikPen (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Liprolog Mix50 than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Liprolog Mix50). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Liprolog Mix50 (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Liprolog Mix50 than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi (se punkt 3: Hvis du har taget for meget Liprolog). hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Liprolog (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Liprolog than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).
Senere i denne indlægsseddel beskrives, hvordan du skal behandle et let tilfælde af hypoglykæmi. hvis du er allergisk (overfølsom) over for insulin lispro eller et af de øvrige indholdsstoffer i Humalog Mix50 (angivet i punkt 6).
Further in this leaflet it tells you how to deal with mild hypoglycaemia (see Section 3: If you take more Humalog Mix50 than you need). if you are allergic (hypersensitive) to insulin lispro or any of the other ingredients of this medicine (listed in section 6).