natgillin/translations-raw huggingface dataset:
Ikke almindelige bivirkninger (kan forekomme hos op til 1 ud af 100 personer) - brystsmerter, ændringer i elektrokardiogram, hurtig puls - nedsat eller unormal hudfølsomhed, prikkende fornemmelse, opmærksomhedsforstyrrelser, 
Uncommon side effects (may affect up to 1 in 100 people) - chest pain, changes in electrocardiogram, rapid heart beating - decreased or abnormal skin sensitivity, pins and needles, attention disturbance, loss of memory,
● som er ART-erfarne uden mutationer associeret med darunavirresistens (DRV-RAMs), og som har plasma hiv-1-RNA < 100.000 kopier/ml og CD4+-celletal ≥ 100 x 10 
● ART-experienced with no darunavir resistance associated mutations (DRV-RAMs) and who have plasma HIV-1 RNA < 100,000 copies/ml and CD4+ cell count ≥ 100 cells x 10
TLOVR non-VF censureret algoritme baseret på hiv-1-RNA < 50 kopier/ml med undtagelse af TITAN (hiv-1 RNA < 400 kopier/ml) 
darunavir amprenavir atazanavir indinavir lopinavir saquinavir tipranavir a TLOVR non-VF censored algorithm based on HIV-1 RNA < 50 copies/ml, except for TITAN (HIV-1 RNA < 400
Plasmakoncentrationer af disse lægemidler kan stige ved samtidig administration af darunavir med lavdosis ritonavir, hvilket fører til reducerede serumkortisolkoncentrationer. 
Plasma concentrations of these medicinal products may be increased when co-administered with darunavir with low dose ritonavir, resulting in reduced serum cortisol concentrations.
Pravastatin 40 mg som enkeldosis pravastatin AUC ↑ 81% pravastatin Cmin ND pravastatin Cmax ↑ 63% en op til 5 gangs forøgning blev set hos en begrænset undergruppe af forsøgspersoner 
pravastatin Cmin ND pravastatin Cmax ↑ 63% an up to five-fold increase was seen in a limited subset of subjects
Baseret på teoretiske overvejelser forventes darunavir at øge plasmakoncentrationen af alfuzosin. 
Based on theoretical considerations darunavir is expected to increase alfuzosin plasma concentrations.
375 mg darunavir + 50 mg ritonavir to gange dagligt mellem 30 og 40 kg 
375 milligram darunavir + 50 milligram ritonavir twice a day between 30 and 40 kilograms
- Tag altid darunavir sammen med 100 mg ritonavir. 
- Take darunavir always together with 100 milligram of ritonavir.
Darunavir binder sig især til surt plasma 1glykoprotein. 
Darunavir binds primarily to plasma α1-acid glycoprotein.
Darunavir co-administreret med lavdosis ritonavir og amiodaron, bepridil, dronedaron, ivabradin quinidin eller ranolazin er kontraindiceret (se pkt. 
Darunavir co-administered with low dose ritonavir and amiodarone, bepridil, dronedarone, ivabradine, quinidine, or ranolazine is contraindicated (see section 4.3).
Amitriptylin Desipramin Imipramin Nortriptylin Trazodon paroxetin AUC ↓ 39% paroxetin Cmin ↓ 37% paroxetin Cmax ↓ 36% #darunavir AUC ↔ darunavir Cmin ↔ darunavir Cmax ↔ sertralin AUC ↓ 49% sertralin Cmin ↓ 49% sertralin Cmax ↓ 44% darunavir AUC ↔ darunavir Cmin ↓ 6% darunavir Cmax ↔ 
Amitriptyline Desipramine Imipramine Nortriptyline Trazodone paroxetine AUC ↓ 39% paroxetine Cmin ↓ 37% paroxetine Cmax ↓ 36% #darunavir AUC ↔ darunavir Cmin ↔ #darunavir Cmax ↔ sertraline AUC ↓ 49% sertraline Cmin ↓ 49% sertraline Cmax ↓ 44% #darunavir AUC ↔ darunavir Cmin ↓ 6% #darunavir Cmax ↔
Efavirenz i kombination med boostet darunavir en gang dagligt kan medføre suboptimal darunavir Cmin. 
Efavirenz in combination with boosted darunavir once daily may result in sub-optimal darunavir Cmin.
Almindelig opkastning, kvalme, abdominale smerter, forhøjet blodamylase, dyspepsi, abdominal distention, flatulens 
Common diarrhoea vomiting, nausea, abdominal pain, increased blood amylase, dyspepsia, abdominal distension, flatulence
Alle intervaller 
All ranges
darunavir skal derfor tages med cobicistat eller ritonavir og med mad. 
Therefore, darunavir tablets should be taken with cobicistat or ritonavir and with food.
lopinavir AUC ↔ lopinavir Cmin  13% lopinavir Cmax  11% darunavir AUC ↓ 41% darunavir Cmin ↓ 55% darunavir Cmax ↓ 21% baseret på ikke-dosisnormaliserede værdier 
lopinavir AUC ↔ lopinavir Cmin ↑ 13% lopinavir Cmax ↑ 11% darunavir AUC ↓ 41% darunavir Cmin ↓ 55% darunavir Cmax ↓ 21% based upon non dose normalised values
● 80 ART-erfarne hiv-1-smittede pædiatriske patienter i alderen 6 til 17 år med en legemsvægt på mindst 20 kg som blev behandlet med darunavir tabletter sammen med lavdosis ritonavir to gange dagligt i kombination med andre antiretrovirale lægemidler. 
● 80 ART-experienced HIV-1 infected paediatric patients aged from 6 to 17 years and weighing at least 20 kg who received darunavir tablets with low dose ritonavir twice daily in combination with other antiretroviral agents.
- Slug tabletterne med noget at drikke som f.eks. vand eller mælk. 
- Swallow the tablets with a drink such as water or milk.
Klinisk monitoring anbefales ved administration af boostet duranavir sammen lavdosis ritonavir med disse analgetika. 
Clinical monitoring is recommended when co-administering duranavir with low dose ritonavir with these analgesics.
Darunavir, co-administereret med lavdosis ritonavir kan forventes at øge plasmakoncentrationen af calciumantagonisterne. 
Darunavir coadministered with low dose ritonavir can be expected to increase the plasma concentrations of calcium channel blockers.
Patienter co-inficeret med hepatitis B- og/eller hepatitis C-virus Blandt 1.968 behandlingserfarne patienter, der fik darunavir, co-administreret med ritonavir 600/100 mg to gange dagligt, havde 236 patienter også hepatitis B eller C. Disse patienter havde en større risiko for forhøjelse af hepatisk aminotransferase ved baseline og efter behandlingsstart end patienter uden kronisk viral hepatitis (se pkt. 
Patients co-infected with hepatitis B and/or hepatitis C virus Among 1,968 treatment-experienced patients receiving darunavir co-administered with ritonavir 600/100 mg twice daily, 236 patients were co-infected with hepatitis B or C. Co-infected patients were more likely to have baseline and treatment emergent hepatic transaminase elevations than those without chronic viral hepatitis (see section 4.4).
Informér din læge, hvis du tager: - Amlodipin, diltiazem, disopyramid, carvedilol, felodipin, flecainid, lidocain, metoprolol, mexiletin, nifedipin, nicardipin, propafenon, timolol, verapamil (til hjertesygdom), da den behandlingsmæssige effekt eller bivirkningerne fra disse lægemidler kan øges. 
Tell your doctor if you take: - Amlodipine, diltiazem, disopyramide, carvedilol, felodipine, flecainide, lidocaine, metoprolol, mexiletine, nifedipine, nicardipine, propafenone, timolol, verapamil (for heart disease) as the therapeutic effect or side effects of these medicines may be increased.
Samtidig administration af boostet darunavir og lurasidon, pimozid eller sertindol er kontraindiceret (se punkt 4.3). 
Concominant administration of boosted darunavir and lurasidone, pimozide or sertindole is contraindicated (see section 4.3).
atorvastatin AUC ↑ 3-4 gange atorvastatin Cmin ↑ ≈5,5-10 gange atorvastatin Cmax ↑ ≈2 gange darunavir/ritonavir atorvastatin AUC ↑ 290 % 
Atorvastatin 10 mg once daily atorvastatin AUC ↑ 3-4 fold atorvastatin Cmin ↑ ≈5.5-10 fold atorvastatin Cmax ↑ ≈2 fold #darunavir/ritonavir atorvastatin AUC ↑ 290% Ω
ART-erfarne pædiatriske patienter (3 til 17 år og legemsvægt mindst 15 kg) Det anbefales sædvanligvis at tage darunavir to gange dagligt med ritonavir i forbindelse med et måltid. 
ART-experienced paediatric patients (3 to 17 years of age and weighing at least 15 kg) Darunavir twice daily taken with ritonavir taken with food is usually recommended.
Det anbefales at bruge andre eller supplerende svangerskabsforebyggende metoder, når østrogenbaserede kontraceptiva gives sammen med darunavir og lavdosis ritonavir. 
Alternative or additional contraceptive measures are recommended when oestrogen-based contraceptives are coadministered with boosted darunavir.
rilpivirin AUC ↑ 130% rilpivirin Cmin ↑ 178% rilpivirin Cmax ↑ 79% darunavir AUC ↔ darunavir Cmin ↓ 11% darunavir Cmax ↔ 
Rilpivirine 150 mg once daily rilpivirine AUC ↑ 130% rilpivirine Cmin ↑ 178% rilpivirine Cmax ↑ 79% darunavir AUC ↔ darunavir Cmin ↓ 11% darunavir Cmax ↔
Antal forsøgspersoner med virologisk svigt a og fænotypedata, som udviser resistens over for PI'er ved endepunktet c, n/N 
Number of subjects with virologic failurea and phenotype data that show resistance to PIs at endpointc, n/N
Spørg på apoteket, hvordan du skal bortskaffe medicinrester. 
Ask your pharmacist how to throw away any medicines you no longer use.
 30 kg til < 40 kg 
≥ 30 kg to < 40 kg
Alfentanil metabolisees via CYP3A og kan dermed hæmmes af boostet darunavir. 
The metabolism of alfentanil is mediated via CYP3A, and may as such be inhibited by boosted darunavir.
Almene symptomer og reaktioner på administrationsstedet Almindelig træthed 
General disorders and administration site conditions Common
Immunsystemet Ikke almindelig immunrekonstitutionsinflammatorisk syndrom (IRIS), (lægemiddel)overfølsomhed 
Immune system disorders Uncommon immune reconstitution inflammatory syndrome, (drug) hypersensitivity
drospirenon AUC ↑ 58 % drospirenon Cmin ND drospirenon Cmax ↑ 15 % ethinylestradiol AUC  30 % ethinylestradiol Cmin ND ethinylestradiol Cmax  14 % med darunavir/cobicistat ethinylestradiol AUC ↓ 44% 
drospirenone Cmax ↑ 15% ethinylestradiol AUC  30% ethinylestradiol Cmin ND€
Dosis til børn på 3 år og over, der vejer mindst 15 kg, og som har taget antiretrovirale lægemidler før (dit barns læge vil fastlægge dette) Lægen beregner den korrekte daglige dosis ud fra barnets vægt (se tabellen herunder). 
Dose for children of 3 years of age and above, weighing at least 15 kilograms who have taken antiretroviral medicines before (your child's doctor will determine this) The doctor will work out the right dose based on the weight of the child (see table below).
Tag ikke Darunavir Mylan: 
Do not take Darunavir Mylan
30 filmovertrukne tabletter 60 filmovertrukne tabletter 90 filmovertrukne tabletter 
30 film-coated tablets 60 film-coated tablets 90 film-coated tablets
Dosis til børn på 3 år og over, der vejer mindst 15 kg, og som ikke har taget antiretrovirale lægemidler før (dit barns læge vil fastlægge dette) Lægen beregner den korrekte daglige dosis, der skal tages én gang dagligt, ud fra barnets vægt (se tabellen herunder). 
Dose for children of 3 years of age and above, weighing at least 15 kilograms who have not taken antiretroviral medicines before (your child's doctor will determine this) The doctor will work out the right once daily dose based on the weight of the child (see table below).
Den samlede farmakokinetiske, forstærkende effekt af ritonavir medførte en ca. 14-fold stigning i den systemiske eksponering for darunavir ved administration af en oral enkeltdosis darunavir på 600 mg i kombination med ritonavir 100 mg to gange dagligt. 
The overall pharmacokinetic enhancement effect by ritonavir was an approximate 14-fold increase in the systemic exposure of darunavir when a single dose of 600 mg darunavir was given orally in combination with ritonavir at 100 mg twice daily.
Du må ikke stoppe med at tage Darunavir Mylan uden først at tale med din læge Lægemidler til behandling af hiv kan få dig til at føle dig bedre. 
Do not stop taking Darunavir Mylan without talking to your doctor first Anti-HIV medicine may make you feel better.
Vedrørende kliniske studieresultater for ART-naive pædiatriske patienter i alderen 12 til 17 år henvises til produktresuméet for darunavir 400 mg og 800 mg tabletter. 
For clinical trial results in ART-naïve paediatric patients aged 12 to 17 years, refer to the Summary of Product Characteristics for darunavir 400 mg and 800 mg tablets.
● 12 ART-naive hiv-1-smittede pædiatriske patienter i alderen 12 til 17 år med en legemsvægt på mindst 40 kg, som fik darunavir tabletter sammen med lavdosis ritonavir en gang dagligt i kombination med andre antiretrovirale lægemidler (se pkt. 
● 12 ART-naïve HIV-1 infected paediatric patients aged from 12 to 17 years and weighing at least 40 kg who received darunavir tablets with low dose ritonavir once daily in combination with other antiretroviral agents (see section 5.1).
Elbasvir/grazoprevir Darunavir med lavdosis ritonavir kan medføre en stigning i eksponeringen for grazoprevir. 
Darunavir with low dose ritonavir may increase the exposure to grazoprevir.
12,2)d 
(1.9; 25.3)d d
- Øvrige indholdsstoffer: kolloid vandfri silica, mikrokrystallinsk cellulose, crospovidon, natriumcarboxymethylstivelse, hypromellose, magnesiumstearat. 
- The other ingredients are colloidal anhydrous silica, cellulose microcrystalline, crospovidone, sodium starch glycolate, hypromellose, magnesium stearate.
Meget almindelig udslæt (herunder makulært, makulopapulært, papulært, erytematøst, pruritisk udslæt, generaliseret udslæt og allergisk dermatitis) 
Not known rash (including macular, maculopapular, papular, erythematous, pruritic rash, generalised rash, and allergic dermatitis)
Darunavir Mylan 75 mg, 150 mg, 300 mg og 600 mg tabletter kan anvendes til at sammensætte passende behandlingsregimer (se pkt. 
Darunavir Mylan 75 mg, 150 mg, 300 mg and 600 mg tablets may be used to provide suitable dose regimens (see section 4.2):
Warfarinkoncentrationer kan blive påvirket ved samtidig administration af boostet darunavir. 
Warfarin concentrations may be affected when coadministered with boosted darunavir.
atorvastatin AUC ↑ 3-4 gange atorvastatin Cmin ↑ ≈5,5-10 gange atorvastatin Cmax ↑ ≈2 gange #darunavir/ritonavir 
Atorvastatin 10 mg once daily atorvastatin AUC ↑ 3-4 fold atorvastatin Cmin ↑ ≈5.5-10 fold atorvastatin Cmax ↑ ≈2 fold darunavir/ritonavir
Samtidig administration af darunavir med lavdosis ritonavir og quetiapin er kontraindiceret, da quetiapin-relateret toksicitet derved kan øges. 
Concomitant administration of darunavir with low dose ritonavir and quetiapine is contraindicated as it may increase quetiapinerelated toxicity.
Der skal udvises forsigtighed, og om muligt anbefales monitorering af terapeutisk koncentration for disse antiarytmika ved coadministration med darunavir med lavdosis ritonavir. 
Caution is warranted and therapeutic concentration monitoring, if available, is recommended for these antiarrhythmics when coadministered with darunavir with low dose ritonavir.
Det kan inkludere gulfarvning af din hud eller det hvide i dine øjne, mørk (tefarvet) urin, bleg afføring, kvalme, opkast, appetitløshed, smerte, ømhed eller smerter og ubehag i højre side under dine ribben. 
These may include yellowing of your skin or whites of your eyes, dark (tea coloured) urine, pale coloured stools (bowel movements), nausea, vomiting, loss of appetite, or pain, aching, or pain and discomfort on your right side below your ribs.
Darunavir 400 mg og 800 mg tabletter kan anvendes til at sammensætte regimet med 800 mg en gang dagligt. 
Darunavir 400 mg and 800 mg tablets can be used to construct the once daily 800 mg regimen.
4.5) - sildenafil - ved behandling af pulmonal arteriel hypertension, avanafil - simvastatin, lovastatin og lomitapid (se pkt. 
see section 4.5) - sildenafil - when used for the treatment of pulmonary arterial hypertension, avanafil - simvastatin, lovastatin and lomitapide (see section 4.5) - dabigatran, ticagrelor (see section 4.5).
Lægemidler, som påvirker darunavireksponering (cobicistat som farmakoforstærker) Darunavir og cobicistat metaboliseres via CYP3A, og co-administration med CYP3A-induktorer kan derfor medføre subterapeutisk plasmaeksponering for darunavir. 
Darunavir and cobicistat are metabolised by CYP3A, and co-administration with CYP3A inducers may therefore result in subtherapeutic plasma exposure to darunavir.
Adskillige af interaktionsstudierne (markeret med i tabellen nedenfor) er gennemført med doser af darunavir, der er lavere end den anbefalede dosis, eller med et andet doseringsregime (se pkt. 
Several of the interaction studies (indicated by in the table below) have been performed at lower than recommended doses of darunavir or with a different dosing regimen (see section 4.2 Posology).
Det frarådes at co-administrere boostet Darunavir Mylan og glecaprevir/pibrentasvir. 
It is not recommended to co-administer boosted darunavir with glecaprevir/pibrentasvir.
carbamazepin AUC ↑ 45% carbamazepin Cmin ↑ 54% carbamazepin Cmax ↑ 43% darunavir AUC ↔ darunavir Cmin  15% darunavir Cmax ↔ 
Carbamazepine 200 mg twice daily carbamazepine AUC ↑ 45% carbamazepine Cmin ↑ 54% carbamazepine Cmax ↑ 43% darunavir AUC ↔ darunavir Cmin ↓ 15% darunavir Cmax ↔
Samtidig administration af darunavir med lavdosis ritonavir og elbasvir/grazoprevir er kontraindiceret (se punkt 4.3). 
Concomitant use of darunavir with low dose ritonavir and elbasvir/grazoprevir is contraindicated (see section 4.3).
Det anbefales udelukkende at anvende 75 mg og 150 mg tabletter til at opnå den anbefalede dosis til voksne, når der er besvær med at synke tabletterne på 300 mg eller 600 mg. Spædbørn og små børns evne til at synke hele tabletter skal vurderes, inden ordination af darunavir-tabletter. 
The use of 75 mg and 150 mg tablets to achieve the recommended dose is appropriate when there is a difficulty in swallowing the 300 mg or 600 mg tablets.
Almindelig opkastning, mavesmerter, abdominal distension, dyspepsi, flatulens, forhøjede pancreas-enzymer 
Uncommon diarrhoea, nausea vomiting, abdominal pain, abdominal distension, dyspepsia, flatulence, pancreatic enzymes increased pancreatitis acute
Der blev ikke observeret krydsresistens med andre hiv-PI'er i de virologiske svigt fra GS-US-216-130-studiet. 
In the virologic failures of the GS-US-216-130 trial no cross-resistance with other HIV PIs was observed.
ethinylestradiol AUC ↓ 44% β ethinylestradiol Cmin ↓ 62% β ethinylestradiol Cmax ↓ 32% β norethindron AUC ↓ 14% β norethindron Cmin ↓ 30% β norethindron Cmax  β β med darunavir/ritonavir 
ethinylestradiol Cmax  14% € with darunavir/cobicistat ethinylestradiol AUC ↓ 44% ethinylestradiol Cmin ↓ 62% ethinylestradiol Cmax ↓ 32% norethindrone AUC ↓ 14% norethindrone Cmin ↓ 30% norethindrone Cmax ↔ β with darunavir/ritonavir
Samtidig administration af boostet darunavir og alfuzosin er kontraindiceret (se punkt 4.3). 
Co-administration of boosted darunavir and alfuzosin is contraindicated (see section 4.3).
(induktion af CYP enzymerne) 
(induction of CYP450 enzymes)
En sikker og effektiv dosis af sildenafil til behandling af pulmonal arteriel hypertension administreret sammen med darunavirog lavdosis ritonavir er ikke fastlagt. 
A safe and effective dose of sildenafil for the treatment of pulmonary arterial hypertension co-administered with darunavir and low dose ritonavir has not been established.
- højt blodtryk, rødmen - røde eller tørre øjne - feber, hævelse af nedre lemmer pga. væske, utilpashed, irritabilitet, smerte - symptomer på infektion, herpes simplex - rejsningsbesvær, forstørrelse af bryster - soveproblemer, døsighed, depression, angst, unormale drømme, nedsat seksualdrift 
- high blood pressure, flushing - red or dry eyes - fever, swelling of lower limbs due to fluids, malaise, irritability, pain - symptoms of infection, herpes simplex - erectile dysfunction, enlargement of breasts - sleeping problems, sleepiness, depression, anxiety, abnormal dreams, decrease in sexual drive
indinavir AUC ↑ 23% indinavir Cmin ↑ 125% indinavir Cmax  darunavir AUC ↑ 24% darunavir Cmin ↑ 44% darunavir Cmax ↑ 11% 
Indinavir 800 mg twice daily indinavir AUC ↑ 23% indinavir Cmin ↑ 125% indinavir Cmax ↔ #darunavir AUC ↑ 24% darunavir Cmin ↑ 44% #darunavir Cmax ↑ 11%
Co-administreret boostet darunavir og amiodaron, bepridil, dronedaron, ivabradin, quinidin eller ranolazin er kontraindiceret (se pkt. 
Co-administration of boosted darunavir and amiodarone, bepridil, dronedarone, ivabradine, quinidine, or ranolazine is contraindicated (see section 4.3).
Co-administration af boostet Darunavir Mylan og naloxegol er kontraindiceret. 
Co-administration of boosted darunavir and naloxegol is contraindicated.
Darunavir, administreret sammen med lavdosis ritonavir, er i kombination med andre antiretrovirale lægemidler indiceret til behandling af patienter med human immundefektvirus (hiv-1)-infektion. 
Darunavir co-administered with low dose ritonavir is indicated in combination with other antiretroviral medicinal products for the treatment of patients with human immunodeficiency virus (HIV-1) infection.
Der skal udvises forsigtighed, og om muligt anbefales monitorering af terapeutisk koncentration for disse antiarytmika ved coadministration med boostet darunavir. 
Caution is warranted and ther apeutic concentration monitoring, if available, is recommended for these antiarrhythmics when co-administered with boosted darunavir.
Se produktresuméet for darunavir 75 mg, 150 mg, 300 mg eller 600 mg tabletter. 
See the Summary of Product Characteristics for darunavir 75 mg, 150 mg, 300 mg or 600 mg tablets.
Darunavir i kombination med cobicistat eller ritonavir påvirker ikke eller kun i ubetydelig grad Trafikog arbejdssikkerhed. 
Darunavir in combination with cobicistat or ritonavir has no or negligible influence on the ability to drive and use machines.
Anbefalet dosis af darunavir-tabletter og ritonavir a til behandlingsnaive pædiatriske patienter (3 til 17 år) 
Recommended dose for treatment-naïve paediatric patients (3 to 17 years) with darunavir tablets and ritonavir a
Eksponeringen for disse immunsuppresiva vil øges ved samtidig administration af darunavir og lavdosis ritonavir. 
Exposure to these immunosuppressants will be increased when co-administered with darunavir co-administered with low dose ritonavir.
Et dosisregime med darunavir taget med ritonavir en gang dagligt i forbindelse med et måltid kan anvendes til patienter, der tidligere har været eksponeret for antiretrovirale lægemidler, men uden mutationer associeret med darunavir resistens (DRV-RAMs)*, og som har plasma-hiv-1-RNA < 100.000 kopier/ml og CD4+-celletal  100 x 10 
A once daily dose regimen of darunavir taken with ritonavir taken with food may be used in patients with prior exposure to antiretroviral medicinal products but without darunavir resistance associated mutations (DRV-RAMs)* and who have plasma HIV-1 RNA < 100,000 copies/ml and CD4+ cell count ≥ 100 cells x 10
Co-administration af parenteral midazolam med darunavir coadministreret med lavdosis ritonavir kan give en kraftig forøgelse af koncentrationen af dette benzodiazepin. 
If parenteral midazolam is coadministered with darunavir coadministered with low dose ritonavir it may cause a large increase in the concentration of this benzodiazepine.
60 filmovertrukne tabletter 240 filmovertrukne tabletter 
60 film-coated tablets 240 film-coated tablets
Koncentrationerne af disse lægemidler kan øges ved coadministration med darunavir med lavdosis ritonavir, hvilket kan øge risikoen for de bivirkninger, der normalt ses med disse midler. 
Concentrations of these medicinal products may be increased when co-administered with darunavir with low dose ritonavir resulting in the potential for increased adverse events usually associated with these agents.
Æske til flaske 
Bottle carton
Co-administration af darunavir og ritonavir med lægemidler, som primært metaboliseres af CYP2D6 (såsom flecainid, propafenon, metoprolol), kan resultere i en øget plasmakoncentration af disse lægemidler, hvilket kan øge eller forlænge deres terapeutiske effekt og bivirkninger. 
Co-administration of darunavir and ritonavir with medicinal products which are primarily metabolised by CYP2D6 (such as flecainide, propafenone, metoprolol) may result in increased plasma concentrations of these medicinal products, which could increase or prolong their therapeutic effect and adverse reactions.
450 mg darunavir + 60 mg ritonavir to gange dagligt mere end 40 kg* 
450 milligram darunavir + 60 milligram ritonavir twice a day more than 40 kilograms*
rosuvastatin AUC ↑ 48% rosuvastatin Cmax ↑ 144% baseret på offentliggjorte data med darunavir/ritonavir rosuvastatin AUC ↑ 93 % rosuvastatin Cmax ↑ 277 % rosuvastatin Cmin ND med darunavir/cobicistat 800/150 mg 
Rosuvastatin 10 mg once daily rosuvastatin AUC ↑ 48%║ rosuvastatin Cmax ↑ 144% ║ based on published data with darunavir/ritonavir rosuvastatin AUC ↑ 93%§ rosuvastatin Cmax ↑ 277% rosuvastatin Cmin ND§
480 filmovertrukne tabletter 480 x 1 filmovertrukne tabletter 
Blister carton 480 film-coated tablets 480 x 1 film-coated tablets