natgillin/translations-raw huggingface dataset:
Hvis du er holdt op med at tage Ziagen af en eller anden grund - særligt hvis det er, fordi du mener, at du har bivirkninger, eller fordi du har en anden sygdom:
If you have stopped taking Ziagen for any reason - especially because you think you are having side effects, or because you have other illness:
Abacavir anbefales ikke til patienter med moderat og svært nedsat leverfunktion.
Abacavir is not recommended in patients with moderate or severe hepatic impairment.
Tages den orale opløsning efter doseringsanbefalingerne, indeholder hver dosis på 15 ml ca. 5 g sorbitol.
When taken according to the dosage recommendations each 15 ml dose contains approximately 5 g of sorbitol.
Derudover er effekten og sikkerheden af abacavir, givet én gang daglig, blevet demonstreret i et pivotalt klinisk studie (CNA30021- se pkt.
Additionally, the efficacy and safety of abacavir given once daily has been demonstrated in a pivotal clinical study (CNA30021See section 5.1 Clinical experience).
Myokardieinfarkt
Myocardial Infarction
• udbredt udslæt med blisterdannelse og hudafskalning, særligt omkring munden, næsen, øjnene og kønsdelene (Stevens-Johnsons syndrom) og i alvorlige tilfælde med hudafskalning på mere end 30 % af kroppens overflade (toksisk epidermal nekrolyse)
• a widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome), and a more severe form causing skin peeling in more than 30% of the body surface (toxic epidermal necrolysis)
Overfølsomhed over for abacavir eller over for et eller flere af hjælpestofferne anført i pkt 6.1.
Hypersensitivity to abacavir or to any of the excipients listed in section 6.1.
Ensartet klinisk succes (punktestimat for behandlingsforskel -1.7, 95 % CI -8.4 - 4.9) blev observeret for begge regimer.
Similar clinical success (point estimate for treatment difference -1.7, 95% CI -8.4, 4.9) was observed for both regimens.
Ziagen oral opløsning findes i high density polyethylenflasker med børnesikret låg, som indeholder 240 ml.
Ziagen oral solution is supplied in high density polyethylene bottles with child-resistant closures, containing 240 ml of oral solution.
For at undgå genoptagelse af abacavir-behandling bør patienter, der har oplevet en formodet overfølsomhedsreaktion, instrueres i at bortskaffe deres resterende Ziagen-tabletter.
• In order to avoid restarting abacavir, patients who have experienced a suspected HSR should be instructed to dispose of their remaining Ziagen tablets
Hvis abacavir bruges til patienter med let nedsat leverfunktion er omhyggelig monitorering påkrævet, herunder monitorering af plasmakoncentrationen af abacavir, hvis det er muligt (se pkt.
If abacavir is used in patients with mild hepatic impairment, then close monitoring is required, including monitoring of abacavir plasma levels if feasible (see sections 4.4 and 5.2).
Hvis behandling med 2 daglige doser er uhensigtsmæssig, kan behandling med én daglig dosis (16 mg/kg) overvejes.
If a twice daily regimen is not feasible, a once daily regimen (16 mg/kg/day) could be considered.
Den gennemsnitlige (CV) AUC over et doseringsinterval på 12 timer var 6,02 µg·time/ml (29 %), ækvivalent med en daglig AUC på ca. 12,0 µg·time/ml.
The mean (CV) AUC over a dosing interval of 12 hours was 6.02 µg.h/ml (29%), equivalent to a daily AUC of approximately 12.0 µg.h/ml.
Klinisk relevans af disse data hos mennesker er ikke kendt.
Clinical relevance in human of these data is unknown.
I reproduktionstoksicitetsstudier blev der observeret embryo- og føtal-toksicitet hos rotter, men ikke hos kaniner.
In reproductive toxicity studies, embryo and foetal toxicity have been observed in rats but not in rabbits.
Ziagen oral opløsning er en klar til gullig opløsning, der kan blive brunlig over tid, og som har jordbær/banansmag.
Ziagen oral solution is clear to yellowish in colour which may turn into a brown colour over time with strawberry/banana flavouring.
Metabolisme og ernæring Almindelig: Appetitmangel Meget sjælden: Laktacidose
Metabolism and nutrition disorders Common: anorexia Very rare: lactic acidosis
Generelt viser tilgængelige data fra kohortestudier og randomiserede studier uoverensstemmelser, således kan der hverken be- eller afkræftes en årsagssammenhæng mellem abacavirbehandling og risiko for myokardieinfarkt.
Overall the available data from observational cohorts and from randomised trials show some inconsistency so can neither confirm nor refute a causal relationship between abacavir treatment and the risk of myocardial infarction.
Gule, bikonvekse, kapselformede tabletter med delekærv, der er præget ”GX 623” på begge sider.
The scored tablets are yellow, biconvex, capsule shaped and are engraved with ‘GX 623' on both sides.
Karcinogenicitetsstudier hos mus og rotter af oralt administreret abacavir viste en stigning i forekomsten af ond- og godartede tumorer.
Carcinogenicity studies with orally administered abacavir in mice and rats showed an increase in the incidence of malignant and non-malignant tumours.
Lægen vil eventuelt holde ekstra øje med dig, så længe du tager Ziagen.
Your doctor may need to monitor you while you are taking Ziagen.
Randomiseret sammenligning af en behandling, som indeholdt dosering med abacavir og lamivudin én gang daglig vs. dosering 2 gange daglig blev foretaget indenfor et randomiseret, multicenter, kontrolleret studie med HIV-inficerede pædiatriske patienter.
A randomised comparison of a regimen including once daily vs twice daily dosing of abacavir and lamivudine was undertaken within a randomised, multicentre, controlled study of HIV-infected, paediatric patients.
Dyrestudier har vist toksicitet over for det udviklende embryon og foster hos rotter, men ikke hos kaniner (se pkt.
Animal studies have shown toxicity to the developing embryo and foetus in rats, but not in rabbits (see section 5.3).
-2,3 % (95 % CI -9,3 % - +4,7 %), p=0,52
-2.3% (95% CI -9.3% to +4.7%), p=0.52
• Tidligere behandlede voksne
• Therapy experienced adults
Fremstiller: Glaxo Operations UK Ltd (trading as Glaxo Wellcome Operations), Priory Street, Ware, Hertfordshire, SG12 0DJ, Storbritannien.
Glaxo Operations UK Ltd (trading as Glaxo Wellcome Operations), Priory Street, Ware, Hertfordshire, SG 12 0DJ, United Kingdom.
Virologisk respons baseret på HIV-1-RNA under 80 kopier/ml plasma ved uge 48 og uge 96 ved én gang daglig versus 2 gange daglig dosering af abacavir + lamivudin; randomisering af ARROW (observationsanalyse)
Virological Response Based on Plasma HIV-1 RNA less than 80 copies/ml at Week 48 and Week 96 in the Once Daily versus Twice Daily abacavir + lamivudine randomisation of ARROW (Observed Analysis)
Ved uge 48 var andelen af patienter med hiv-RNA < 50 kopier/ml 63 %, 80 % og 86 % for henholdsvis ZDV/3TC/ABC, ZDV/3TC/EFV og ZDV/3TC/ABC/EFV.
At week 48 the proportion of subjects with HIV RNA <50 copies/ml were 63%, 80% and 86% for the ZDV/3TC/ABC, ZDV/3TC/EFV and ZDV/3TC/ABC/EFV arms, respectively.
Tripel nukleosidterapi
Triple nucleoside therapy
Brug doseringssprøjten til oral administration, der ligger i pakningen, til at afmåle den nøjagtige dosis.
Use the oral dosing syringe supplied with the pack to measure your dose accurately.
MINDSTEKRAV TIL MÆRKNING PÅ BLISTERKORT ELLER BLISTERSTRIPS
MINIMUM PARTICULARS TO APPEAR ON BLISTERS OR STRIPS TABLET BLISTER FOIL TEXT
Efter 36 uger på et behandlingsregime indeholdende abacavir og lamivudin 2 gange daglig blev 669 egnede patienter randomiseret til enten at fortsætte med dosering 2 gange daglig eller skifte til abacavir og lamivudin én gang daglig i minimum 96 uger.
After 36 weeks on a regimen including twice daily abacavir and lamivudine, 669 eligible subjects were randomised to either continue twice daily dosing or switch to once daily abacavir and lamivudine for at least 96 weeks.
Sæt tilpasningsstykket af plastik i flaskehalsen.
Push the plastic adapter into the neck of the bottle
Der foreligger ingen kliniske data for patienter med moderat og svært nedsat leverfunktion, hvorfor abacavir ikke bør anvendes, medmindre det vurderes nødvendigt.
In patients with moderate or severe hepatic impairment, no clinical data are available, therefore the use of abacavir is not recommended unless judged necessary.
Børn (som vejer under 25 kg):
Children (weighing less than 25 kg):
Indlægsseddel: Information til brugeren Ziagen 300 mg filmovertrukne tabletter
Package leaflet: Information for the user Ziagen 300 mg Film-coated tablets
Hvis du har glemt at tage Ziagen
If you forget to take Ziagen
Ziagen filmovertrukne tabletter er præget med 'GX 623' på begge sider og forsynet med delekærv.
Ziagen film-coated tablets are engraved with ‘GX 623' on both sides.
I et farmakokinetisk studie (PENTA 15) skiftede fire virologisk kontrollerede patienter under 12 måneder fra abacavir plus lamivudin oral opløsning to gange daglig til dosering én gang daglig.
In a pharmacokinetic study (PENTA 15), four virologically controlled subjects less than 12 months of age switched from abacavir plus lamivudine oral solution twice daily to a once daily regimen.
Placer sprøjten i munden med spidsen mod indersiden af kinden.
Remove the syringe from the adapter Put the syringe into your mouth, placing the tip of the syringe against the inside of your cheek.
Kombinationsbehandling såsom Ziagen kan forårsage udvikling af andre sygdomme under behandlingen af hiv.
Combination therapy including Ziagen may cause other conditions to develop during HIV treatment.
Ved skift tilbage til 2 daglige doser skal patienten tage den første af de to anbefalede daglige doser ca. 24 timer efter den sidste dosis.
When changing back to a twice daily regimen, patients should take the recommended twice daily dose approximately 24 hours after the last once daily dose.
Ziagen og lignende medicin kan give fosteret bivirkninger.
Ziagen and similar medicines may cause side effects in unborn babies.
Der skal tages højde for, at data vedrørende behandling med én daglig dosis er meget begrænsede hos denne population (se pkt.
It should be taken into account that data for the once daily regimen are very limited in this population (see sections 5.1 and 5.2).
Hos hiv-inficerede patienter med svær immuninsufficiens kan der ved påbegyndelse af antiretroviral kombinationsbehandling (CART) opstå en inflammatorisk reaktion på asymptomatiske eller residuale opportunistiske infektioner.
In HIV-infected patients with severe immune deficiency at the time of initiation of combination antiretroviral therapy (CART) an inflammatory reaction to asymptomatic or residual opportunistic infections may arise.
Disse symptomer kan føre til fejldiagnosticering af overfølsomhed som respiratorisk sygdom (pneumoni, bronkitis, faryngitis) eller gastroenteritis.
Importantly, such symptoms may lead to misdiagnosis of HSR as respiratory disease (pneumonia, bronchitis, pharyngitis), or gastroenteritis .
Voksne, unge og børn (som vejer mindst 25 kg):
Adults, adolescents and children (weighing at least 25 kg):
Administration 2 gange daglig (300 mg):
Twice daily (300 mg) administration:
Hos patienter med leverinsufficiens, herunder kronisk aktiv hepatitis, ses oftere abnorm leverfunktion i forbindelse med den antiretrovirale behandling, og disse patienter skal kontrolleres i henhold til standardpraksis.
Patients with pre-existing liver dysfunction, including chronic active hepatitis, have an increased frequency of liver function abnormalities during combination antiretroviral therapy, and should be monitored according to standard practice.
-1,6 % (95 % CI -8.4 % - +5,2 %), p=0,65
-1.6% (95% CI -8.4% to +5.2%), p=0.65
Et fertilitetsstudie hos rotter viste, at abacavir ikke påvirkede hanlig eller hunlig fertilitet.
A fertility study in the rat has shown that abacavir had no effect on male or female fertility.
Pakningen indeholder en 10 ml doseringssprøjte og et tilpasningsstykke i plastik til flasken.
A 10 ml oral dosing syringe and a plastic adapter for the bottle are included in the pack.
-4,8 % (95 % CI -11,5 % - +1,9 %), p=0,16
-4.8% (95% CI -11.5% to +1.9%), p=0.16
Tabletovertræk: Triacetin, methylhydroxypropylcellulose, titandioxid, polysorbat 80 og gul jernoxid.
The tablet coating contains triacetin, methylhydroxypropylcellulose, titanium dioxide, polysorbate 80 and iron oxide yellow.
Da Ziagen indeholder abacavir kan nogle patienter, som tager Ziagen, få en overfølsomhedsreaktion (alvorlig allergisk reaktion), som kan være livstruende, hvis behandling med Ziagen fortsættes.
Since Ziagen contains abacavir some patients taking Ziagen may develop a hypersensitivity reaction (serious allergic reaction) which can be life-threatening if treatment with Ziagen is continued.
Børn, som får abacavir-tabletter i henhold til doseringsanbefalingerne, opnår højere abacavir-plasmaniveauer end børn, som får oral opløsning, da der administreres højere mg/kg-doser med tabletformuleringen.
Children receiving abacavir oral tablets according to the recommended dosage regimen achieve higher plasma abacavir exposure than children receiving oral solution because higher mg/kg doses are administered with the tablet formulation.
Øvrige symptomer omfatter:
Other symptoms include:
Et farmakokinetisk studie viste, at samtidig administration af 600 mg abacavir 2 gange daglig og methadon reducerede Cmax for abacavir med 35 % og udsatte tmax med en time, men AUC var uændret.
Methadone: in a pharmacokinetic study, co-administration of 600 mg abacavir twice daily with methadone showed a 35% reduction in abacavir Cmax and a one hour delay in tmax but the AUC was unchanged.
Læs oplysningerne under 'Andre bivirkninger ved kombinationsbehandling af hiv' i punkt 4 i denne indlægsseddel.
Read the information ‘Other possible side effects of combination therapy for HIV' in Section 4 of this leaflet.
Hvis din samlede dosis f.eks. er 30 ml, skal du tage 3 sprøjter fyldt med medicin.
For example, if your dose is 30 ml, you need to take 3 syringe-fulls of medicine Take the syringe out of the bottle and wash it thoroughly in clean water.
Tryk langsomt stemplet i bund, så du får tid til at synke medicinen.
Slowly push the plunger in, allowing time to swallow.
Virkning og anvendelse Ziagen anvendes til behandling af hiv-infektioner (humant immundefektvirus).
What Ziagen is and what it is used for Ziagen is used to treat HIV (human immunodeficiency virus) infection.
Procent med < 400 pr. ml vRNA
Percent with <400 copies/ml vRNA
For at undgå overførsel af hiv anbefales det, at hiv-inficerede kvinder under ingen omstændigheder ammer deres børn.
It is recommended that HIV infected women do not breast-feed their infants under any circumstances in order to avoid transmission of HIV.
Træk i sprøjtens stempel, indtil sprøjten indeholder den første mængde af din samlede dosis.
Pull out the syringe plunger until the syringe contains the first part of your full dose Turn the bottle the right way up.
Disse var primært asymptomatiske hiv-inficerede patienter - Centre for Disease Control and Prevention (CDC) stadie A. De blev randomiseret til at modtage enten abacavir 600 mg én gang daglig eller 300 mg 2 gange daglig, i kombination med efavirenz og lamivudin givet én gang daglig.
These were primarily asymptomatic HIV infected patients - Centre for Disease Control and Prevention (CDC) stage A. They were randomised to receive either abacavir 600 mg once daily or 300 mg twice daily, in combination with efavirenz and lamivudine given once daily.
Selv patienter, som ikke har genet HLA-B*5701, kan udvikle en overfølsomhedsreaktion (en alvorlig allergisk reaktion).
Even patients who don't have the HLA-B*5701 gene may still develop a hypersensitivity reaction (a serious allergic reaction).
Fordelen ved Ziagen er hovedsageligt baseret på resultater af studier med voksne behandlingsnaive patienter med et regime af Ziagen 300 mg 2 gange daglig i kombination med zidovudin og lamivudin.
The demonstration of the benefit of Ziagen is mainly based on results of studies performed in adult treatment-naïve patients using a regimen of Ziagen 300 mg twice daily in combination with zidovudine and lamivudine.
Hvis du er overfølsom over for Ziagen, skal du returnere alle dine Ziagen-tabletter, så de kan blive destrueret korrekt.
If you are hypersensitive to Ziagen, return all your unused Ziagen tablets for safe disposal.
Indlægsseddel: Information til brugeren Ziagen 20 mg/ml oral opløsning
Package leaflet: Information for the user Ziagen 20 mg/ml oral solution
I et studie af 20 hiv-inficerede patienter der fik abacavir 300 mg 2 gange daglig, med kun én 300 mg dosis indtaget før prøveudtagning efter 24 timer, var den geometriske gennemsnitlige terminale carbovir-TP intracellulære halveringstid ved steady state 20,6 timer, sammenlignet med den geometriske gennemsnitlige abacavir plasmahalveringstid i dette studie på 2,6 timer.
In a study of 20 HIV-infected patients receiving abacavir 300 mg twice daily, with only one 300 mg dose taken prior to the 24 hour sampling period, the geometric mean terminal carbovir-TP intracellular half-life at steady-state was 20.6 hours, compared to the geometric mean abacavir plasma half-life in this study of 2.6 hours.
Øvrige indholdsstoffer: Sorbitol 70 % (E420), saccharinnatrium, natriumcitrat, vandfri citronsyre, methylparahydroxybenzoat (E218), propylparahydroxybenzoat (E216), propylenglycol (E1520), maltodextrin, mælkesyre, glyceryltriacetat, syntetisk jordbær- og banansmag, renset vand, natriumhydroxid og/eller saltsyre til pH-justering.
The other ingredients are sorbitol 70% (E420), saccharin sodium, sodium citrate, citric acid anhydrous, methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), propylene glycol (E1520), maltodextrin, lactic acid, glyceryl triacetate, artificial strawberry and banana flavour, purified water, sodium hydroxide and/or hydrochloric acid for pH adjustment.
Indeholder blandt andet: sorbitol (340 mg/ml, E420), methylparahydroxybenzoat (E218) og propylparahydroxybenzoat (E216).
Contains amongst others: sorbitol (340 mg/ml, E420), methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216).
Ziagen findes også som oral opløsning (20 mg abacavir/ml) til børn over tre måneder med en kropsvægt under 14 kg, eller til patienter, der har behov for en lavere dosis, eller som ikke kan synke tabletter.
An oral solution (20 mg abacavir/ml) is also available for the treatment of children over three months of age and weighing less than 14 kg, or for people who need a lower than usual dose, or who cannot take tablets.
Autoimmune sygdomme (som f.eks. Graves´ sygdom og autoimmun hepatitis) er også blevet rapporteret i forbindelse med immunreaktivering; dog er den rapporterede tid til frembrud mere variabel, og frembrud kan forekomme mange måneder efter behandlingsstart (se pkt.
Autoimmune disorders (such as Graves' disease and autoimmune hepatitis) have also been reported to occur in the setting of immune reactivation; however, the reported time to onset is more variable and these events can occur many months after initiation of treatment (see section 4.4).
Gult jernoxid.
Iron oxide yellow
Hvis du er overfølsom over for Ziagen, skal du returnere al din Ziagen oral opløsning, så det kan blive destrueret korrekt.
If you are hypersensitive to Ziagen, return all your unused Ziagen oral solution for safe disposal.
Plasma HIV-1-RNA <80 kopier/ml Risikodifference (én gang daglig vs. to gange daglig)
Plasma HIV-1 RNA <80 c/ml Risk difference (once daily-twice daily)
Glaxo Operations UK Ltd. (registreret som GlaxoWellcome Operations) Harmire Road
Glaxo Operations UK Ltd (trading as GlaxoWellcome Operations) Harmire Road
Hos voksne, behandlet med abacavir i kombination med lamivudin og zidovudin, var andelen af patienter med en udetekterbar virusbyrde (< 400 kopier/ml) ca. 70 % (”intention to treat”-analyse efter 48 uger) med et tilsvarende øget CD4-celletal.
In adults treated with abacavir in combination with lamivudine and zidovudine the proportion of patients with undetectable viral load (<400 copies/ml) was approximately 70% (intention to treat analysis at 48 weeks) with corresponding rise in CD4 cells.
Adapteren sættes i flaskehalsen og sprøjten sættes fast i adaptoren.
The adapter is placed in the neck of the bottle and the syringe attached to this.
ViiV Healthcare BV, Huis ter Heideweg 62, 3705 LZ Zeist, Holland
ViiV Healthcare BV, Huis ter Heideweg 62, 3705 LZ Zeist, Netherlands
Det er vigtigt, at du tager Ziagen regelmæssigt, da der er større risiko for at få en overfølsomhedsreaktion, hvis du tager medicinen uregelmæssigt.
It is important to take Ziagen regularly, because if you take it at irregular intervals, you may be more likely to have a hypersensitivity reaction.
Glaxo Operations UK Ltd. (registreret som GlaxoWellcome Operations), Harmire Road, Barnard Castle, Co. Durham DL12 8DT, Storbritannien eller ViiV Healthcare Trading Services UK Limited, 12 Riverwalk, Citywest Business Campus, Dublin 24, Irland
Manufacturer: Glaxo Operations UK Ltd, (trading as GlaxoWellcome Operations) Harmire Road Barnard Castle Co. Durham DL12 8DT United Kingdom or ViiV Healthcare Trading Services UK Limited, 12 Riverwalk,
Ziagen indeholder også konserveringsmidler (parahydroxybenzoater), der kan udløse en overfølsomhedsreaktion (eventuelt forsinket).
Ziagen also contains preservatives (parahydroxybenzoates) which may cause allergic reactions (possibly delayed).
Overfølsomhedsreaktioner (se også pkt.
Hypersensitivity reactions (see also section 4.8)
Administration én gang daglig (600 mg):
Once daily (600 mg) administration:
I cellekulturer blev abacavirs antivirale aktivitet ikke antagoniseret ved kombination med nukleosid revers transkriptasehæmmerne (NRTI'er) didanosin, emtricitabin, lamivudin, stavudin, tenofovir eller zidovudin, non-nukleosid revers transkriptasehæmmeren (NNRTI) nevirapin eller proteasehæmmeren (PI) amprenavir.
The antiviral activity of abacavir in cell culture was not antagonized when combined with the nucleoside reverse transcriptase inhibitors (NRTIs) didanosine, emtricitabine, lamivudine, stavudine, tenofovir or zidovudine, the non-nucleoside reverse transcriptase inhibitor (NNRTI) nevirapine, or the protease inhibitor (PI) amprenavir.
I prækliniske toksikologiske studier blev det påvist, at behandling med abacavir øgede levervægten hos rotter og aber.
In pre-clinical toxicology studies, abacavir treatment was shown to increase liver weights in rats and monkeys.
Metylhydroxypropylcellulose Titandioxid
Methylhydroxypropylcellulose Titanium dioxide Polysorbate 80
Hvis du holder op med at tage Ziagen
If you have stopped taking Ziagen
123 (74 %) ud af de 166 forsøgspersoner havde M184V/I, 50 (30 %) havde T215Y/F, 45 (27 %) havde M4IL, 30 (18 %) havde K70R og 25 (15 %) havde D67N.
In a meta-analysis of five clinical trials where abacavir was added to intensify therapy, of 166 subjects, 123 (74%) had M184V/I, 50 (30%) had T215Y/F, 45 (27%) had M41L, 30 (18%) had K70R and 25 (15%) had D67N.
Ifølge kliniske studier med børn absorberes abacavir hurtigt og godt, når det gives som oral opløsning og tabletter.
According to clinical trials performed in children abacavir is rapidly and well absorbed from oral solution and tablet formulations administered to children.
Filmovertrukne tabletter
Film-coated Tablets
Dosisjustering af Ziagen er ikke nødvendig hos patienter med nyreinsufficiens.
No dosage adjustment of Ziagen is necessary in patients with renal dysfunction.
Ud over bivirkninger ved Ziagen nævnt nedenfor, kan du få andre sygdomme, når du får kombinationsbehandling mod hiv.
As well as the side effects listed below for Ziagen, other conditions can develop during combination therapy for HIV.
Ligeledes havde en større andel af børn behandlet med kombinationer, som indeholdte abacavir, HIV-1-RNA ≤ 50 kopier/ml ved 48 uger (henholdsvis 53 %, 42 % og 28 %, p=0,07).
Similarly, greater proportions of children treated with the abacavir containing combinations had HIV-1 RNA ≤50 copies/ml at 48 weeks (53%, 42% and 28% respectively, p=0.07).