natgillin/translations-raw huggingface dataset:
Du må ikke stoppe med at tage Darunavir Mylan uden først at tale med din læge Lægemidler til behandling af hiv kan få dig til at føle dig bedre.
Do not stop taking Darunavir Mylan without talking to your doctor first Anti-HIV medicine may make you feel better.
Vedrørende kliniske studieresultater for ART-naive pædiatriske patienter i alderen 12 til 17 år henvises til produktresuméet for darunavir 400 mg og 800 mg tabletter.
For clinical trial results in ART-naïve paediatric patients aged 12 to 17 years, refer to the Summary of Product Characteristics for darunavir 400 mg and 800 mg tablets.
● 12 ART-naive hiv-1-smittede pædiatriske patienter i alderen 12 til 17 år med en legemsvægt på mindst 40 kg, som fik darunavir tabletter sammen med lavdosis ritonavir en gang dagligt i kombination med andre antiretrovirale lægemidler (se pkt.
● 12 ART-naïve HIV-1 infected paediatric patients aged from 12 to 17 years and weighing at least 40 kg who received darunavir tablets with low dose ritonavir once daily in combination with other antiretroviral agents (see section 5.1).
Elbasvir/grazoprevir Darunavir med lavdosis ritonavir kan medføre en stigning i eksponeringen for grazoprevir.
Darunavir with low dose ritonavir may increase the exposure to grazoprevir.
12,2)d
(1.9; 25.3)d d
- Øvrige indholdsstoffer: kolloid vandfri silica, mikrokrystallinsk cellulose, crospovidon, natriumcarboxymethylstivelse, hypromellose, magnesiumstearat.
- The other ingredients are colloidal anhydrous silica, cellulose microcrystalline, crospovidone, sodium starch glycolate, hypromellose, magnesium stearate.
Meget almindelig udslæt (herunder makulært, makulopapulært, papulært, erytematøst, pruritisk udslæt, generaliseret udslæt og allergisk dermatitis)
Not known rash (including macular, maculopapular, papular, erythematous, pruritic rash, generalised rash, and allergic dermatitis)
Darunavir Mylan 75 mg, 150 mg, 300 mg og 600 mg tabletter kan anvendes til at sammensætte passende behandlingsregimer (se pkt.
Darunavir Mylan 75 mg, 150 mg, 300 mg and 600 mg tablets may be used to provide suitable dose regimens (see section 4.2):
Warfarinkoncentrationer kan blive påvirket ved samtidig administration af boostet darunavir.
Warfarin concentrations may be affected when coadministered with boosted darunavir.
atorvastatin AUC ↑ 3-4 gange atorvastatin Cmin ↑ ≈5,5-10 gange atorvastatin Cmax ↑ ≈2 gange #darunavir/ritonavir
Atorvastatin 10 mg once daily atorvastatin AUC ↑ 3-4 fold atorvastatin Cmin ↑ ≈5.5-10 fold atorvastatin Cmax ↑ ≈2 fold darunavir/ritonavir
Samtidig administration af darunavir med lavdosis ritonavir og quetiapin er kontraindiceret, da quetiapin-relateret toksicitet derved kan øges.
Concomitant administration of darunavir with low dose ritonavir and quetiapine is contraindicated as it may increase quetiapinerelated toxicity.
Der skal udvises forsigtighed, og om muligt anbefales monitorering af terapeutisk koncentration for disse antiarytmika ved coadministration med darunavir med lavdosis ritonavir.
Caution is warranted and therapeutic concentration monitoring, if available, is recommended for these antiarrhythmics when coadministered with darunavir with low dose ritonavir.
Det kan inkludere gulfarvning af din hud eller det hvide i dine øjne, mørk (tefarvet) urin, bleg afføring, kvalme, opkast, appetitløshed, smerte, ømhed eller smerter og ubehag i højre side under dine ribben.
These may include yellowing of your skin or whites of your eyes, dark (tea coloured) urine, pale coloured stools (bowel movements), nausea, vomiting, loss of appetite, or pain, aching, or pain and discomfort on your right side below your ribs.
Darunavir 400 mg og 800 mg tabletter kan anvendes til at sammensætte regimet med 800 mg en gang dagligt.
Darunavir 400 mg and 800 mg tablets can be used to construct the once daily 800 mg regimen.
4.5) - sildenafil - ved behandling af pulmonal arteriel hypertension, avanafil - simvastatin, lovastatin og lomitapid (se pkt.
see section 4.5) - sildenafil - when used for the treatment of pulmonary arterial hypertension, avanafil - simvastatin, lovastatin and lomitapide (see section 4.5) - dabigatran, ticagrelor (see section 4.5).
Lægemidler, som påvirker darunavireksponering (cobicistat som farmakoforstærker) Darunavir og cobicistat metaboliseres via CYP3A, og co-administration med CYP3A-induktorer kan derfor medføre subterapeutisk plasmaeksponering for darunavir.
Darunavir and cobicistat are metabolised by CYP3A, and co-administration with CYP3A inducers may therefore result in subtherapeutic plasma exposure to darunavir.
Adskillige af interaktionsstudierne (markeret med i tabellen nedenfor) er gennemført med doser af darunavir, der er lavere end den anbefalede dosis, eller med et andet doseringsregime (se pkt.
Several of the interaction studies (indicated by in the table below) have been performed at lower than recommended doses of darunavir or with a different dosing regimen (see section 4.2 Posology).
Det frarådes at co-administrere boostet Darunavir Mylan og glecaprevir/pibrentasvir.
It is not recommended to co-administer boosted darunavir with glecaprevir/pibrentasvir.
carbamazepin AUC ↑ 45% carbamazepin Cmin ↑ 54% carbamazepin Cmax ↑ 43% darunavir AUC ↔ darunavir Cmin  15% darunavir Cmax ↔
Carbamazepine 200 mg twice daily carbamazepine AUC ↑ 45% carbamazepine Cmin ↑ 54% carbamazepine Cmax ↑ 43% darunavir AUC ↔ darunavir Cmin ↓ 15% darunavir Cmax ↔
Samtidig administration af darunavir med lavdosis ritonavir og elbasvir/grazoprevir er kontraindiceret (se punkt 4.3).
Concomitant use of darunavir with low dose ritonavir and elbasvir/grazoprevir is contraindicated (see section 4.3).
Det anbefales udelukkende at anvende 75 mg og 150 mg tabletter til at opnå den anbefalede dosis til voksne, når der er besvær med at synke tabletterne på 300 mg eller 600 mg. Spædbørn og små børns evne til at synke hele tabletter skal vurderes, inden ordination af darunavir-tabletter.
The use of 75 mg and 150 mg tablets to achieve the recommended dose is appropriate when there is a difficulty in swallowing the 300 mg or 600 mg tablets.
Almindelig opkastning, mavesmerter, abdominal distension, dyspepsi, flatulens, forhøjede pancreas-enzymer
Uncommon diarrhoea, nausea vomiting, abdominal pain, abdominal distension, dyspepsia, flatulence, pancreatic enzymes increased pancreatitis acute
Der blev ikke observeret krydsresistens med andre hiv-PI'er i de virologiske svigt fra GS-US-216-130-studiet.
In the virologic failures of the GS-US-216-130 trial no cross-resistance with other HIV PIs was observed.
ethinylestradiol AUC ↓ 44% β ethinylestradiol Cmin ↓ 62% β ethinylestradiol Cmax ↓ 32% β norethindron AUC ↓ 14% β norethindron Cmin ↓ 30% β norethindron Cmax  β β med darunavir/ritonavir
ethinylestradiol Cmax  14% € with darunavir/cobicistat ethinylestradiol AUC ↓ 44% ethinylestradiol Cmin ↓ 62% ethinylestradiol Cmax ↓ 32% norethindrone AUC ↓ 14% norethindrone Cmin ↓ 30% norethindrone Cmax ↔ β with darunavir/ritonavir
Samtidig administration af boostet darunavir og alfuzosin er kontraindiceret (se punkt 4.3).
Co-administration of boosted darunavir and alfuzosin is contraindicated (see section 4.3).
(induktion af CYP enzymerne)
(induction of CYP450 enzymes)
En sikker og effektiv dosis af sildenafil til behandling af pulmonal arteriel hypertension administreret sammen med darunavirog lavdosis ritonavir er ikke fastlagt.
A safe and effective dose of sildenafil for the treatment of pulmonary arterial hypertension co-administered with darunavir and low dose ritonavir has not been established.
- højt blodtryk, rødmen - røde eller tørre øjne - feber, hævelse af nedre lemmer pga. væske, utilpashed, irritabilitet, smerte - symptomer på infektion, herpes simplex - rejsningsbesvær, forstørrelse af bryster - soveproblemer, døsighed, depression, angst, unormale drømme, nedsat seksualdrift
- high blood pressure, flushing - red or dry eyes - fever, swelling of lower limbs due to fluids, malaise, irritability, pain - symptoms of infection, herpes simplex - erectile dysfunction, enlargement of breasts - sleeping problems, sleepiness, depression, anxiety, abnormal dreams, decrease in sexual drive
indinavir AUC ↑ 23% indinavir Cmin ↑ 125% indinavir Cmax  darunavir AUC ↑ 24% darunavir Cmin ↑ 44% darunavir Cmax ↑ 11%
Indinavir 800 mg twice daily indinavir AUC ↑ 23% indinavir Cmin ↑ 125% indinavir Cmax ↔ #darunavir AUC ↑ 24% darunavir Cmin ↑ 44% #darunavir Cmax ↑ 11%
Co-administreret boostet darunavir og amiodaron, bepridil, dronedaron, ivabradin, quinidin eller ranolazin er kontraindiceret (se pkt.
Co-administration of boosted darunavir and amiodarone, bepridil, dronedarone, ivabradine, quinidine, or ranolazine is contraindicated (see section 4.3).
Co-administration af boostet Darunavir Mylan og naloxegol er kontraindiceret.
Co-administration of boosted darunavir and naloxegol is contraindicated.
Darunavir, administreret sammen med lavdosis ritonavir, er i kombination med andre antiretrovirale lægemidler indiceret til behandling af patienter med human immundefektvirus (hiv-1)-infektion.
Darunavir co-administered with low dose ritonavir is indicated in combination with other antiretroviral medicinal products for the treatment of patients with human immunodeficiency virus (HIV-1) infection.
Der skal udvises forsigtighed, og om muligt anbefales monitorering af terapeutisk koncentration for disse antiarytmika ved coadministration med boostet darunavir.
Caution is warranted and ther apeutic concentration monitoring, if available, is recommended for these antiarrhythmics when co-administered with boosted darunavir.
Se produktresuméet for darunavir 75 mg, 150 mg, 300 mg eller 600 mg tabletter.
See the Summary of Product Characteristics for darunavir 75 mg, 150 mg, 300 mg or 600 mg tablets.
Darunavir i kombination med cobicistat eller ritonavir påvirker ikke eller kun i ubetydelig grad Trafikog arbejdssikkerhed.
Darunavir in combination with cobicistat or ritonavir has no or negligible influence on the ability to drive and use machines.
Anbefalet dosis af darunavir-tabletter og ritonavir a til behandlingsnaive pædiatriske patienter (3 til 17 år)
Recommended dose for treatment-naïve paediatric patients (3 to 17 years) with darunavir tablets and ritonavir a
Eksponeringen for disse immunsuppresiva vil øges ved samtidig administration af darunavir og lavdosis ritonavir.
Exposure to these immunosuppressants will be increased when co-administered with darunavir co-administered with low dose ritonavir.
Et dosisregime med darunavir taget med ritonavir en gang dagligt i forbindelse med et måltid kan anvendes til patienter, der tidligere har været eksponeret for antiretrovirale lægemidler, men uden mutationer associeret med darunavir resistens (DRV-RAMs)*, og som har plasma-hiv-1-RNA < 100.000 kopier/ml og CD4+-celletal  100 x 10
A once daily dose regimen of darunavir taken with ritonavir taken with food may be used in patients with prior exposure to antiretroviral medicinal products but without darunavir resistance associated mutations (DRV-RAMs)* and who have plasma HIV-1 RNA < 100,000 copies/ml and CD4+ cell count ≥ 100 cells x 10
Co-administration af parenteral midazolam med darunavir coadministreret med lavdosis ritonavir kan give en kraftig forøgelse af koncentrationen af dette benzodiazepin.
If parenteral midazolam is coadministered with darunavir coadministered with low dose ritonavir it may cause a large increase in the concentration of this benzodiazepine.
60 filmovertrukne tabletter 240 filmovertrukne tabletter
60 film-coated tablets 240 film-coated tablets
Koncentrationerne af disse lægemidler kan øges ved coadministration med darunavir med lavdosis ritonavir, hvilket kan øge risikoen for de bivirkninger, der normalt ses med disse midler.
Concentrations of these medicinal products may be increased when co-administered with darunavir with low dose ritonavir resulting in the potential for increased adverse events usually associated with these agents.
Æske til flaske
Bottle carton
Co-administration af darunavir og ritonavir med lægemidler, som primært metaboliseres af CYP2D6 (såsom flecainid, propafenon, metoprolol), kan resultere i en øget plasmakoncentration af disse lægemidler, hvilket kan øge eller forlænge deres terapeutiske effekt og bivirkninger.
Co-administration of darunavir and ritonavir with medicinal products which are primarily metabolised by CYP2D6 (such as flecainide, propafenone, metoprolol) may result in increased plasma concentrations of these medicinal products, which could increase or prolong their therapeutic effect and adverse reactions.
450 mg darunavir + 60 mg ritonavir to gange dagligt mere end 40 kg*
450 milligram darunavir + 60 milligram ritonavir twice a day more than 40 kilograms*
rosuvastatin AUC ↑ 48% rosuvastatin Cmax ↑ 144% baseret på offentliggjorte data med darunavir/ritonavir rosuvastatin AUC ↑ 93 % rosuvastatin Cmax ↑ 277 % rosuvastatin Cmin ND med darunavir/cobicistat 800/150 mg
Rosuvastatin 10 mg once daily rosuvastatin AUC ↑ 48%║ rosuvastatin Cmax ↑ 144% ║ based on published data with darunavir/ritonavir rosuvastatin AUC ↑ 93%§ rosuvastatin Cmax ↑ 277% rosuvastatin Cmin ND§
480 filmovertrukne tabletter 480 x 1 filmovertrukne tabletter
Blister carton 480 film-coated tablets 480 x 1 film-coated tablets
Ikke almindelig artritis urica, anoreksi, nedsat appetit, vægttab, vægtstigning, hyperglykæmi, insulinresistens, nedsat HDL, øget appetit, polydipsi, øget lactatdehydrogenase i blodet
Uncommon diabetes mellitus, hypertriglyceridaemia, hypercholesterolaemia, hyperlipidaemia gout, anorexia, decreased appetite, decreased weight, increased weight, hyperglycaemia, insulin resistance, decreased high density lipoprotein, increased appetite, polydipsia, increased blood lactate dehydrogenase
Den samlede farmakokinetiske, forstærkende effekt af ritonavir var en ca. 14-fold stigning i den systemiske eksponering for darunavir ved administration af en oral enkeltdosis darunavir på 600 mg i kombination med ritonavir 100 mg to gange dagligt (se pkt.
The overall pharmacokinetic enhancement effect by ritonavir was an approximate 14-fold increase in the systemic exposure of darunavir when a single dose of 600 mg darunavir was given orally in combination with ritonavir at 100 mg twice daily (see section 4.4).
Samtidig anvendelse af cochicin og darunavir administreret sammen med lavdosis ritonavir kan øge eksponeringen for colchicin.
Concomitant use of colchicine and darunavir coadministered with low dose ritonavir may increase the exposure to colchicine.
Dolutegravir dolutegravir AUC ↓ 22% dolutegravir C24h ↓ 38% dolutegravir Cmax ↓ 11% darunavir ↔* * Ved brug af historiske farmakokinetiske data på tværs af studier.
HIV ANTIRETROVIRALS Integrase strand transfer inhibitors Dolutegravir dolutegravir AUC ↓ 22% dolutegravir C24h ↓ 38% dolutegravir Cmax ↓ 11% darunavir ↔* * Using cross-study comparisons to historical pharmacokinetic data
Lave forekomster af udvikling af resistent hiv-1-virus blev observeret hos ART-naive patienter, som blev behandlet første gang med darunavir/cobicistat en gang dagligt i kombination med andre ART, og hos ART-erfarne patienter uden darunavir-RAMs, som fik darunavir/cobicistat i kombination med andre ART. Tabellen nedenfor viser udviklingen af hiv-1 protease-mutationer og resistens over for PI'er ved virologiske svigt ved endepunktet i GS-US-216-130-studiet.
Low rates of developing resistant HIV-1 virus were observed in ART-naïve patients who are treated for the first time with darunavir/cobicistat once daily in combination with other ART, and in ARTexperienced patients with no darunavir RAMs receiving darunavir/cobicistat in combination with other ART.
Æske til flaske 480 filmovertrukne tabletter
Bottle carton 480 film-coated tablets
Darunavir, co-administreret med cobicistat, er i kombination med andre antiretrovirale lægemidler indiceret til behandling af human immundefektvirus (hiv-1)-infektion hos voksne patienter (se pkt.
Darunavir co-administered with cobicistat is indicated in combination with other antiretroviral medicinal products for the treatment of human immunodeficiency virus (HIV-1) infection in adult patients (see section 4.2).
 15 kg til < 30 kg
≥ 15 kg to < 30 kg
Darunavir med cobicistat eller ritonavir er ikke blevet testet med alle proteasehæmmere og må ikke bruges med andre hiv-proteasehæmmere.
Darunavir with cobicistat or ritonavir has not been tested with all PIs (protease inhibitors) and must not be used with other HIV PIs.
efavirenz AUC ↑ 21% efavirenz Cmin ↑ 17% efavirenz Cmax ↑ 15% #darunavir AUC ↓ 13% darunavir Cmin ↓ 31% darunavir Cmax ↓ 15% (↑ efavirenz fra CYP3A-hæmning) (↓ darunavir fra CYP3A-induktion)
600 mg once daily efavirenz AUC ↑ 21% efavirenz Cmin ↑ 17% efavirenz Cmax ↑ 15% darunavir AUC ↓ 13% #darunavir Cmin ↓ 31% darunavir Cmax ↓ 15% (↑ efavirenz from CYP3A inhibition) (↓ darunavir from CYP3A induction)
Der er ikke anbefalet dosisjustering af darunavir/ritonavir.
No dose adjustment for darunavir/ritonavir is recommended.
HDPE-flaskepakke med polypropylenskruelåg indeholdende 30, 60 og 90 tabletter.
HDPE bottle pack with a PP screw cap containing 30, 60, 90 tablets.
Det anbefales ikke at co-administrere boostet darunavir og boceprevir.
It is not recommended to co-administer boosted darunavir and boceprevir.
Klinisk monitorering anbefales ved co-administration af darunavir med lavdosis ritonavir og disse antidepressiva, og det kan være nødvendigt at justere dosis af antidepressivummet.
Clinical monitoring is recommended when coadministering darunavir with low dose ritonavir with these antidepressants and a dose adjustment of the antidepressant may be needed.
Effekt af darunavir 800 mg en gang dagligt co-administreret med 150 mg cobicistat en gang dagligt hos ART-naive og ART-erfarne patienter
Efficacy of darunavir 800 mg once daily co-administered with 150 mg cobicistat once daily in ART-naïve and ART-experienced patients
Didanosin skal administreres på tom mave, således at det bliver administreret 1 time før eller 2 timer efter boostet darunavir, taget sammen med føde.
administered 1 hour before or 2 hours after boosted darunavir given with food.
Produktresuméet for cobicistat eller ritonavir, som det måtte være relevant, skal derfor læses, inden behandling med darunavir påbegyndes.
The Summary of Product Characteristics of cobicistat or ritonavir as appropriate, must therefore be consulted prior to initiation of therapy with darunavir.
Hvis efavirenz skal anvendes i kombination med darunavir, bør der anvendes et regime med darunavir/ritonavir 600/100 mg to gange dagligt.
If efavirenz is to be used in combination with darunavir, the darunavir/ritonavir 600/100 mg twice daily regimen should be used.
Efavirenz i kombination med darunavir/ritonavir 800/100 mg en gang dagligt kan medføre suboptimal darunavir Cmin.
Efavirenz in combination with darunavir/ritonavir 800/100 mg once daily may result in suboptimal darunavir Cmin.
Darunavir Mylan 150 mg filmovertrukne tabletter fås i blisterkort med 240 tabletter og i plastbeholdere med 60 og 240 tabletter.
Darunavir Mylan 150 mg film-coated tablets are available in blister packs containing 240 tablets and in plastic bottles containing 60 and 240 tablets.
Se produktresuméet for darunavir 75 mg, 150 mg, 300 mg og 600 mg tabletter (se pkt.
See the Summary of Product Characteristics for darunavir 75 mg, 150 mg, 300 mg and 600 mg tablets (see section 4.5).
Det anbefales ikke at co-administrere darunavir med lavdosis ritonavir og boceprevir.
It is not recommended to coadminister darunavir with low dose ritonavir and boceprevir.
Darunavir Mylan skal altid gives oralt med lavdosis ritonavir som en farmakokinetisk forstærker og i kombination med andre antiretrovirale lægemidler.
Darunavir Mylan must always be given orally with low dose ritonavir as a pharmacokinetic enhancer and in combination with other antiretroviral medicinal products.
Darunavir kan muligvis øge risikoen for forhøjet kaliumindhold i blodet pga. drospirenon.
Darunavir might increase the risk for elevated potassium levels by drospirenone.
4.1), kan der anvendes et regime med 800 mg en gang dagligt sammen med cobicistat 150 mg en gang dagligt eller ritonavir 100 mg en gang dagligt i forbindelse med et måltid.
6/l (see section 4.1) a regimen of 800 mg once daily with cobicistat 150 mg once daily or ritonavir 100 mg once daily taken with food may be used.
Plasmakoncentrationen af lovastatin og simvastatin forventes at stige markant, når de gives sammen med darunavir administreret sammen med lavdosis ritonavir (CYP3A-hæmning)
Lovastatin and simvastatin are expected to have markedly increased plasma concentrations when co-administered with darunavir co-administered with low dose ritonavir.
Hos gnavere var de identificerede målorganer det hæmatopoietiske system, blodkoagulationssystemet, lever og skjoldbruskkirtlen Der blev observeret et variabelt men begrænset fald i parametre for røde blodlegemer samt stigninger i aktiveret, partiel tromboplastintid.
A variable but limited decrease in red blood cell-related parameters was observed, together with increases in activated partial thromboplastin time.
Darunavir/ritonavir 10 kg til < 15 kg N=5
10 kg to < 15 kg N=5
Se doseringsanbefalingerne til ART-naive patienter i produktresuméet for darunavir 400 mg og 800 mg tabletter.
For dosage recommendations in ART-naïve patients see the Summary of Product Characteristics for darunavir 400 mg and 800 mg tablets.
1 tablet a 800 mg darunavir) sammen med 100 mg ritonavir en gang dagligt.
1 tablet containing 800 milligram of darunavir) together with 100 milligram ritonavir once daily.
Sjælden pyrexi, brystsmerter, perifert ødem, utilpashed, varmefølelse, irritabilitet, smerte kulderystelse, unormal følelse, tørhed
Rare asthenia, fatigue pyrexia, chest pain, peripheral oedema, malaise, feeling hot, irritability, pain chills, abnormal feeling, xerosis
Co-administration af parenteral midazolam med boostet darunavir kan give en kraftig forøgelse af koncentrationen af dette benzodiazepin.
If parenteral midazolam is coadministered with boosted darunavir it may cause a large increase in the concentration of this benzodiazepine.
Darunavir Mylan 75 mg filmovertrukne tabletter Hver filmovertrukken tablet indeholder 75 mg darunavir.
Darunavir Mylan 75 mg film-coated tablets Each film-coated tablet contains 75 mg of darunavir.
Med CD4+ celletal (x 10
With Baseline CD4+ cell count (x 10
Samtidig anvendelse af sildenafil eller tadalafil til behandling af pulmonal arteriel hypertension og darunavir administreret sammen med lavdosis ritonavir kan øge plasmakoncentrationen af sildenafil og tadalafil.
Concomitant use of sildenafil or tadalafil for the treatment of pulmonary arterial hypertension and darunavir co-administered with low dose ritonavir may increase plasma concentrations of sildenafil or tadalafil.
Børn og unge Darunavir Mylan må ikke anvendes til børn, der er yngre end 3 år og vejer mindre end 15 kg.
Children and adolescents Darunavir is not for use in children younger than 3 years of age or weighing less than 15 kilograms.
Sjælden pankreatitis, gastritis, gastroøsofageal reflukssygdom, aftøs stomatitis, opkastningsfornemmelser, mundtørhed, mavebesvær, forstoppelse, forhøjet lipase, ræben, oral dysæstesi,
Rare pancreatitis, gastritis, gastrooesophageal reflux disease, aphthous stomatitis, retching, dry mouth, abdominal discomfort, constipation, increased lipase, eructation, oral dysaesthesia stomatitis, haematemesis, cheilitis, dry lip, coated tongue
Hvis du kommer i tanke om den glemte dosis inden for 12 timer, skal du straks tage en dosis.
If you notice within 6 hours, you must take your missed dose immediately.
darunavir virker ikke korrekt uden samtidig indtagelse af mad.
Darunavir cannot work properly without food.
Baseret på teoretiske overvejelser forventes co-administreret boostet darunavir at øge eksponeringen for lomitapid.
Based on theoretical considerations boosted darunavir is expected to increase the exposure of lomitapide when co-administered.
HDPE-flaskepakke med polypropylenskruelåg indeholdende 60 og 240 tabletter.
HDPE bottle pack with a PP screw cap containing 60 and 240 tablets.
Børn Darunavir må ikke anvendes til børn, der er yngre end 3 år og vejer mindre end 15 kg.
Children Darunavir is not for use in children younger than 3 years of age or weighing less than 15 kilograms.