natgillin/translations-raw huggingface dataset:
6.2.5.1 Effekter på sundhed Carvon er en monoterpen (terpenoid keton).
6.2.5.1 Effects on health Carvone is a monoterpene (terpenoid ketone).
L-Carvons sensibiliserende virkning anses normalt for lav, men har af og til forårsaget kontaktallergi hos brugere af pebermynte tandpasta og tyggegummi.
The sensitising potential of L- carvone is normally considered low, but it has occasionally caused contact allergy in users of spearmint toothpaste and chewing gum.
I en lappetest (”patch-test”) undersøgelse af 541 patienter havde 15 (2,8%) positive og 12 tvivlsomme positive reaktioner over for l-carvon.
In a ”patch-test” examination of 541 patients, 15 (2.8%) had positive and 12 had doubtful positive reactions towards L-carvone.
I en gentestning med l-carvon i samme eller lavere koncentrationer havde kun 2 ud af 8 patienter positive reaktioner (Paulsen 1993: HSDB).
In a repeated test with L-carvone in the same or lower concentrations only 2 out of 8 patients had positive reactions (Paulsen 1993: HSDB).
L-carvon er også et oxidationsprodukt af d-limonene, hvis oxidationsprodukter er erkendt som hudsensibiliserende (AT 2002).
L-carvone is also an oxidation product of d-limonene, whose oxidation products are known as skin sensitising (AT 2002).
Akut oral, marsvin LD50
Acute oral guinea pig LD50
Der blev ikke noteret skadelige effekter på kropsvægtsforøgelse eller væsentlige organer og væv inklusiv testikler (Hagan et al. 1967).
No adverse effects were noted on body-weight gain or main organs and tissues, including testes (Hagan et al. 1967).
Dosisniveauet, der ikke medførte toksiske effekter, var således 0,25% i foderet (= 2500 ppm) svarende til 125 mg/kg lgv/dag.
Level causing no toxicological effect was thus 0.25% (= 2500 ppm) in the diet, equivalent to 125 mg/kg bw/day.
Det daglige indtag af carvone (begge isomere) pr. capita er anslået til 2,8 mg/person (JECFA 1999).
The daily intake of carvone (both isomers) per capita is estimated at 2.8 mg/person (JECFA 1999).
Regneeksempel med udgangspunkt i den højest målte migration på 0,65 µg/tandbørste:
Example of calculation based on the highest migration measured to 0.65 µg/toothbrush:
Af ovenstående ses, at ingen af de mængder, der indtages eller optages ved indånding, vil medføre en dosis på over den midlertidige ADI på 1,25 mg/kg lgv/dag, hvorfor dette vurderes ikke at ville indebære nogen sundhedsmæssig risiko.
From the above it is seen that none of the amounts ingested or absorbed at toothbrushing will result in a dose above the temporary ADI of 1.25 mg/kg bw/day, for which reason it is assessed not to involve any health risk.
Carvon indebærer ingen sundhedsmæssig risiko ved indtagelse i de mængder, der er konstateret ved analyse af de udvalgte tandbørster.
Carvone implies no health risks to the consumer by oral intake at the concentrations measured in the selected toothbrushes.
N,N-Dimethyacetamid anvendes mest som opløsningsmiddel (solvent) i industrielle anvendelser.
N,N-Dimethylacetamide is mostly used as a solvent in industrial applications.
N,N-Dimethylacetamid bruges f.eks. som solvent for plastik, harpiks (resins and gums), som katalysator i kemiske processer og i malingfjerner.
N,N-Dimethylacetamid is e.g. used as a solvent for plastics, resins and gums, as catalyst in chemical processes, and paint remover.
N,N-Dimethylacetamid kan opløse polyacrylonitril, polyvinylchlorid, polyamid og polyimid.
Polyacrylonitrile, polyvinylchloride, polyamide and polyimide can be dissolved by N,Ndimethylacetamide.
Dimethylacetamid anvendes desuden i produktionen af film og fibre.
N,N-Dimethylacetamide is furthermore used in the production of films and fibres.
For eksempel angiver BASF, at dimethylacetamid anvendes i produktionen af polyacrylonitril fibre, film og overfladedækkende stoffer som lakker (BASF 2001).
For instance, BASF informs that N,N-dimethylacetamide is used in the production of polyacrylonitril fibres, films and coatings and for special lacquers (BASF 2001).
IUPAC navn N,N-dimethylacetamid
IUPAC name N,N-Dimethylacetamide
dimethylacetamid acetdimethylamid dimethylamid acetat
dimethylacetamide acetdimethylamide dimethylamide acetate
Vandopløseligheden er høj, stoffet er angivet som blandbart med vand ved 25ºC (Budavari 1989).
high, the substance is stated as miscible with water at 25°C (Budavari 1989).
Fordelingskoefficienten n-oktanol/vand log Kow er eksperimentelt målt til -0,77 (Hansch et al. 1995).
The partitioning coefficient n- octanol/water log Kow has experimentally been determined to -0.77 (Hansch et al. 1995).
N,N-dimethylacetamid er klassificeret i Listen over farlige stoffer (Miljøministeriet 2002):
N,N-Dimethylacetamide is classified in the List of Dangerous Substances (Miljøministeriet 2002):
Klassificering i blandinger:
Classification in mixtures: conc.
N,N-Dimethylacetamid absorberes let gennem huden.
N,N-Dimethylacetamide is readily absorbed through the skin.
N,N-Dimethylacetamid kan give systemiske skader ved inhalation eller optagelse over huden i tilstrækkelige mængder over længere tid (Kirk-Othmer 1978).
N,N-Dimethylacetamide is capable of producing systemic injury when inhaled or absorbed through the skin in sufficient quantities over a prolonged period of time (Kirk- Othmer 1978).
N,N-Dimethylacetamid har en lav akut toksicitet ved oral indtagelse eller ved kortvarig kontakt med stoffet som væske eller dampe via øjne eller huden (Kirk-Othmer 1978).
N,N-Dimethylacetamide has a low order of acute toxicity when swallowed or upon brief contact of the liquid or vapour with the eyes or skin (Kirk-Othmer 1978).
2240 mg/kg Akut inhalation, rotte LC50, 1 time 2475 ppm
2240 mg/kg Acute inhalation rat LC50, 1 hour 2475 ppm
Referencen angiver ingen koncentration.
The reference presents no concentration levels.
Ved oral indgift af rotter over 22 dage i graviditetsperioden i 5 doseringer (0, 20, 65, 150 og 400 mg/kg lgv/dag) i grupper af 25 dyr pr. dosering med eksponering i dag 7-21 i drægtighedsperioden blev der fundet signifikante effekter ved 400 mg/kg. NOEL for maternel toksicitet var 65 mg/kg lgv/dag og for teratogen effekt var NOEL på 65 mg/kg lgv/dag (OECD 2002a).
By oral administration of N,N-dimethylacetamide to rats over 22 days during gestation in 5 doses (0, 20, 65, 150 and 400 mg/kg bw/day) in groups of 25 animals per dose with exposure in day 7-21 during gestation significant effects were found at 400 mg/kg. NOEL for maternal toxicity was 65 mg/kg bw/day and for teratogenic effect a NOEL of 65 mg/kg bw/day was found (OECD 2002a).
mærkning H - hudgennemtrængelig (AT 2002).
with skin notation i.e. skin penetrable (AT 2002).
N,N-Dimethylacetamid kan optages via alle eksponeringsveje (indånding, optagelse gennem huden og indtagelse).
N,N-Dimethylacetamide can be absorbed by all exposure routes (inhalation, absorption via skin and by oral intake).
Tabel 6.7 Indtagelse af N,N-dimethylacetamid beregnet ud fra de målte afgivelser
Table 6.7 Ingestion of N,N-dimethylacetamid calculated from the measured releases
N,N-dimethylacetamid indebærer ingen sundhedsmæssig risiko ved indtagelse eller ved indånding i de mængder, der er konstateret ved analyse af de udvalgte tandbørster.
N,N-Dimethylacetamid implies no health risks to the consumer by oral intake or inhalation at the concentrations measured in the selected toothbrushes.
2-Methylbenzensulfonamid bruges som tilsætningsstof i den kemiske industri.
2-Methyl-benzene sulphonamide is mainly used as an additive in the chemical industry.
Mindre mængder bruges i produktionen af saccharin.
Minor amounts are used as a chemical intermediate for the production of Saccharin.
2- og 4-Methylbenzensulfonamid (o- og p-toluensulfonamid) blandinger anvendes som en blødgører i smeltelime (hot-melt adhesives) og til at øge flexibiliteten af overfladedæklag baseret på harpikser (OECD 2002).
A mixture of 2-methyl-benzene sulphonamide and 4methyl-benzene sulphonamide is used as a plasticiser for hot-melt adhesives, a chemical intermediate for fluorescent pigments and a chemical intermediate for plasticiser resins (OECD 2002).
Kan give overfølsomhed ved kontakt med huden 6.2.7.1 Effekter på sundhed
May cause sensitization by skin contact 6.2.7.1 Effects on health
Den akutte toksicitet for rotter er lav med LD50- værdier over 1000 mg/kg lgv.
The acute toxicity for rats is low with LD50- values above 1000 mg/kg bw.
Akut oral rotte, hunner
Acute oral rat, females
Stoffet er moderat øjenirriterende for kaniner.
The substance is moderately eye irritating for rabbits.
Hudirritation er hyppigt beskrevet og antages at være et resultat af sulfonamid-delen af det kemiske stof, da følsomheden stiger med stigende mængde af sulfonamid også i andre kemiske forbindelser (HSDB).
Skin irritation is often described and it is assumed to be a result of the sulphonamide moiety of the chemical substance, as the sensitization increases with increasing amount of sulphonamide, also in other chemical compounds (HSDB).
Ved 100 og 500 mg/kg blev der observeret effekter på adfærd, reduceret vægtforøgelse og histopatologiske ændringer i begge køn på en dosisafhængig måde.
At 100 and 500 mg/kg effects on behaviour, reduced increase in weight and histopathological changes in both sexes in a dose-dependent manner.
Baseret på kliniske tegn og hepatologiske effekter var NOAEL for gentagen dosering sat til 20 mg/kg lgv/dag (OECD 2002b).
Based on clinical signs and hepathological effects NOAEL for repeated dose toxicity was set to 20 mg/kg bw/day (OECD 2002b).
I samme studie blev der observeret signifikant reduktion i kropsvægten hos unger ved fødslen og dag 4 hos begge køn ved 500 mg/kg lgv.
In the same study, significant reduction in body weights of pups was observed at birth and on day 4 in both sexes at 500 mg/kg bw.
Der var dog ingen effekter på reproduktionsparametrene ved op til 500 mg/kg lgv.
There was no change in reproductive parameters at up to 500 mg/kg bw.
Baseret på en samlet vurdering af de to forsøg blev 100 mg/kg lgv/dag anset som passende NOAEL for reproduktionstoksicitet (OECD 2002b).
Based on overall evaluation of both results, 100 mg/kg bw/day for reproductive toxicity is considered to be the appropriate NOAEL (OECD 2002b).
Genotoksicitetstests i bakterie- og pattedyrsceller in vitro var negative.
Genotoxicity tests in bacteria and mammalian cells in vitro were negative.
6.2.7.2 Grænseværdier Ingen fundet
6.2.7.2 Threshold limit values None found.
Tabel 6.8 Analyseresultater og estimeret indtagelse af 2methylbenzensulfonamid
Table 6.8 Analysis results and estimated ingestion of 2-methyl-benzene sulphonamide
2-Methylbenzensulfonamid er således påvist i 2 af produkterne i mængder over detektionsgrænsen på 0,25 µg/tandbørste.
2-Methyl-benzene sulphonamide has thus been detected in 2 of the products in amounts above the detection limit of 0.25 µg/toothbrush.
Baseret på en NOAEL 20 mg/kg lgv og en sikkerhedsmargen på 1000 er der anvendt en tolerabel koncentration på 20/1000 = 20 µg/kg lgv/dag.
Based on a NOAEL 20 mg/mg bw and a safety factor of 1000 a tolerable concentration of 20/1000 = 20 µg/kg bw/day has been used.
Af ovenstående ses, at ingen af de mængder, der indtages eller optages ved tandbørstning, vil medføre en dosis på over 20 µg/kg, hvorfor dette vurderes ikke at ville indebære nogen sundhedsmæssig risiko.
From the above it is seen that none of the amounts being ingested or absorbed by toothbrushing, will result in a dose of more than 20 µg/kg, for which reason it is assessed not to involve any health risk.
2-Methylbenzensulfonamid indebærer ingen sundhedsmæssig risiko ved indtagelse i de mængder, der er konstateret ved analyse af de udvalgte tandbørster.
2-Methyl-benzene sulphonamide implies no health risks to the consumer by oral intake at the concentrations measured migrating from the selected toothbrushes.
2- og 4-Methylbenzensulfonamid (o- og p-toluensulfonamid) blandinger anvendes som en reaktiv blødgører (reactive plasticizer) i smeltelime (hot-melt adhesives) og til at øge flexibiliteten af overfladedæklag baseret på harpikser (OECD 2002b).
Mixtures of 2- and 4-methyl-benzene sulphonamide ( = o- and p-toluene sulphonamides) are used as a reactive plasticiser in hot-melt adhesives and to increase the flexibility of surface finishing coat based on resins (OECD 2002b).
UNEP (1995) anfører, at 4-methylbenzensulfonamid anvendes som råmateriale i syntesen af pesticider og fluorescerende farver og pharmaceutiske stoffer, samt at det anvendes som blødgører i varmekrympende plast (”thermosetting resins”) i koncentrationer under 1%.
UNEP (1995) mentions that 4-methyl-benzene sulphonamide is used as raw material for the synthesis of pesticides, fluorescent colorants and drugs and that it is also used as plasticiser for thermosetting resins below 1%.
Kogepunktet er 214ºC ved 1,33 kPa (10 mmHg) (Kirk-Othmer 1982).
The boiling point is 214°C at 1.33 kPa (10 mmHg) (Kirk- Othmer 1982).
Vandopløseligheden er 3160 mg/l ved 25ºC (Yalkowsky og Dannenfelser 1992).
The water solubility is 3160 mg/l at 25°C (Yalkowsky and Dannenfelser 1992).
Eftersom mange af de skadelige effekter synes at være overfølsomhedsreaktioner, er der ingen specifik dosis.
Since many of the adverse effects appear to be hypersensitivity reactions there is no specific toxic dose.
Tilfældene af effekter synes at være korreleret med sulfonamid (HSDB).
The incidence of the adverse effects appears to increase with increased sulphonamide dosage (HSDB).
Der er ikke fundet megen litteratur om akutte letale effekter efter hudkontakt eller oral indtag.
There has not been found much literature about acute lethal effects after skin contact or oral intake.
De fleste data er fundet i en OECD/SIDS rapport (UNEP 1995).
Most of the data have been found in an OECD/SIDS report (UNEP 1995).
Af andre data er der fundet resultater fra en kombineret screeningstest på effekter på udvikling og reproduktion udført efter OECD TG 422.
A combined repeat dose and reproductive/developmental toxicity screening test was performed according to OECD TG 422.
Der blev anvendt doserne 0, 120, 300 og 750 mg/kg indgivet oralt med slange i 42 dage til hanrotter og i 14 dage før parring til dag 3 i dieperioden hos hunnerne.
Doses of: 0, 120, 300 and 750 mg/kg/day were administered by oral gavage for 42 days to male rats and from day 14 before mating through day 3 of lactation to female rats.
4Methylbenzen-sulfonamid viste ingen genotoksiske effekter, og LOAEL for gentagen dosering var 120 mg/kg lgv/dag (UNEP 1995).
4Methyl-benzene sulphonamide did not show any genotoxic effects, and LOAEL (lowest adverse effect level) for repeated dose toxicity was established as 120 mg/kg bw/day (UNEP 1995).
TDI: 0,024 mg/kg lgv/dag .
TDI: 0.024 mg/kg bw/day.
Der er ingen data fundet om hudoptagelse.
No data have been found regarding skin absorption.
Da der ikke er data for optagelsen, er der anvendt 100% optagelse.
As there are no data for the absorption, 100% ingestion has been used.
Tabel 6.9 Analyseresultater og skønnet indtagelse af 4
Table 6.9 Analysis results and estimated ingestion of 4-methyl-benzene sulphonamide
Baseret på studiet af gentagen oral eksponering, blev der udledt en tolerabel dosering på 0,024 mg/kg lgv/dag.
Based on the study of repeated oral exposure, a tolerable dose of 0.024 mg/kg bw/day was established.
Af ovenstående ses, at ingen af de mængder, der indtages eller optages ved tandbørstning, vil medføre en dosis på over 24 µg/kg, hvorfor dette vurderes ikke at ville indebære nogen sundhedsmæssig risiko.
From the table above it is seen that none of the amounts being ingested or absorbed by toothbrushing, will result in a dose of more than 24 µg/kg, for which reason it is assessed not to involve any health risk.
4-Methylbenzensulfonamid indebærer ingen sundhedsmæssig risiko ved indtagelse i de mængder, der er konstateret ved analyse af de udvalgte tandbørster.
4-Methyl-benzene sulphonamide implies no health risks to the consumer by oral intake at the concentrations measured in the analyses of the selected toothbrushes.
1-Methyl-2-pyrrolidinon anvendes som opløsningsmiddel for harpikser (resiner), dispergeringsmiddel for pigmenter og som bestanddel i PVC produktionen.
1-Methyl-2-pyrrolidinone is used as solvent for resins, pigment dispersant and as constituent in the PVC production.
1-Methyl-2-pyrrolidinon anvendes primært som ekstraktionsmiddel i den petrokemiske industri, som et reaktivt medium i polymer og non-polymer kemiske reaktioner, til fjernelse af graffiti og maling.
1-Methyl-2-pyrrolidinone is mainly used as a solvent for extraction in the petrochemical industry, as a reactive medium in polymeric and non-polymeric chemical reactions, as a remover of graffiti and paint.
1-Methyl-2-pyrrolidinon bruges også i formuleringen af pigmenter, farvestoffer, trykfarver og i produktionen af pesticider.
1-Methyl-2pyrrolidinone is also used as a formulating agent in pigments, dyes, and inks and in the production of pesticides.
1-Methyl-2-pyrrolidinon anvendes også i den farmaceutiske industri til af forøge gennemtrængeligheden af medicin påført huden og som bærestof i den kosmetiske industri.
1-Methyl-2-pyrrolidinone is further used as an intermediate in the pharmaceutical industry, as a penetration enhancer for topically applied drugs, and as a vehicle in the cosmetics industry.
Damptrykket er 46 Pa ved 25ºC (0,345 mmHg) (Daubert og Danner 1989).
The vapour pressure is 46 Pa at 25°C (0.345 mmHg) (Daubert and Danner 1989).
Vandopløseligheden er høj (blandbart) ved 25ºC (Lewis 1993).
The water solubility is high (miscible) mg/l at 25°C (Lewis 1993).
1-Methyl-2-pyrrolidinone er klassificeret i Listen over farlige stoffer (Miljøministeriet 2002):
1-Methyl-2-pyrrolidinone is classified in the List of Dangerous Substances (Miljøministeriet 2002):
1-Methyl-2-pyrrolidinon er øjenirriterende (Kirk Othmer 1982).
1-Methyl-2-pyrrolidinon is eye irritating (Kirk Othmer 1982).
Stoffet akutte toksicitet er lav: Akut oral, rotte
The acute toxicity of the substance is low: Acute oral rat
I et 28 dages fødetoksicitetsstudie med gentagen dosering blev rotter indgivet 0, 2000, 6000, 18000 eller 30000 ppm 1-methyl-2-pyrrolidinon.
In a 28-day diet toxicity study with repeated dose 0, 2000, 6000, 18000 or 30000 ppm 1-Methyl-2-pyrrolidinone were administered to the rats.
In vivo parametre, hæmatologiske og klinisk-kemiske parametre, samt en komplet patologisk vurdering blev udført efter 28 dage.
In vivo parameters, haemathological and clinical-chemical parameters, together with a complete pathological evaluation were carried out after 28 days.
NOAEL var 6000 ppm (429 mg/kg lgv) for hanrotter og 18000 ppm (1548 mg/kg lgv) for hunrotter (Malek et al. 1997).
NOAEL was 6000 ppm (429 mg/kg bw) in males and 18000 ppm (1548 mg/kg bw) in females (Malek et al. 1997).
NOAEL var 514 mg/kg lgv (CICAD 2001).
The NOAEL in this study was 514 mg/kg bw (CICAD 2001).
Beregnet ud fra kropsvægten var den daglige gennemsnitsdosis 0, 169, 433 og 1057 mg/kg lgv hos hanner og 0, 217, 565 og 1344 mg/kg lgv hos hunner.
pyrrolidinone dose was 0, 169, 433 and 1057 mg/kg body weight in males and0, 217, 565 and 1344 mg/kg bw in females.
Et dosisrelateret fald i kropsvægt blev observeret fra 7500 ppm.
A dose-related decrease in body weight was observed from 7500 ppm.
Sammen med andre observationer af klinisk og adfærdsmæssig art fastsattes NOAEL til 3000 ppm svarende til 169 mg/kg lgv hos hanner og 217 mg/kg lgv hos hunner (CICAD 2001).
Together with other observations of clinical and behavioural kind, the NOAEL for this study was 3000 ppm equivalent to 169 mg/kg bw in males and 217 mg/kg bw in females (CICAD 2001).
Der findes ingen grænseværdi for arbejdsmiljø i øjeblikket.
At the moment, there is no Danish threshold limit value.
Baseret på akutte data er foreslået en tysk grænseværdi (MAK) på 20 ppm; svarende til 80 mg/m3; med anmærkning H for hudgennemtrængelighed (DF 2001).
Based on acute data a German maximum value for the working environment (MAK) of 20 ppm has been suggested; this corresponds to 80 mg/m3; with skin notation (DF 2001).
En amerikansk grænseværdi for arbejdsmiljø (TWA: 8 timer) er 10 ppm med note om hudgennemtrængelighed (AIHA 1999).
An American threshold limit value for the working environment (TWA, 8 hour) is 10 ppm with skin notation (AIHA 1999).
Ved anbringelse på hud blev 61 til 70% af dosis genfundet i urin over 5 dage, hvoraf det meste inden for 24 timer.
When applied on the skin 61 to 70% of the dose was recovered in urine over 5 days, of which most of it within 24 hours.
6-7% blev afgivet med udåndingsluft og 1-2% med fæces.
6 to 7% was released with the expiration air and 1 to 2% with faeces.
Ved oral indgivelse blev 85-88% genfundet i urinen inden for de første 5 dage (Midgley et al. 1992).
By oral ingestion 85 to 88% was recovered in the urine within the first 5 days (Midgley et al. 1992).
Optagelsen er fundet så høj, at det er anset for rimeligt at anvende 100% absorption.
The absorption was so high that is considered reasonable to use 100% adsorption in the evaluation.
Barnets vægt er sat til 10 kg og absorptionen (biotilgængeligheden) til 100%, da størsteparten må anses for optaget.
The weight of the child has been set at 10 kg, and the absorption (bioavailability) at 100%.
Tabel 6.10 Analyseresultater og skønnet indtagelse af 1-methyl-2pyrrolidinon
Table 6.10 Analysis results and estimated ingestion of 1-methyl-2pyrrolidinone
Til vurdering af oral eksponering er anvendt NOAEL på 169 mg/kg lgv/dag fra 90-dages studiet.
For the evaluation of oral exposure, NOAEL of 169 mg/kg bw/day from the 90-days study is used.
En tolerabel koncentration (TDI) er herefter beregnet som:
Subsequently, a tolerable concentration (TDI) has been calculated as:
Usikkerhedsfaktoren på 300 sammensat af flere faktorer, dvs. 10 for artsforskel (interspecies variation), 10 for interindividuel variation hos mennesker, og 3 for en justering fra 90-dages studiet til kronisk eksponering (IPCS, 1994).
The uncertainty factor of 300 was combined from several factors, i.e. 10 for interspecies variation, 10 for interindividual variation at humans and 3 for an adjustment from the 90-days study to a chronic exposure (IPCS 1994).
Af ovenstående ses, at ingen af de mængder, der eksponeres for ved tandbørstning, vil medføre en dosis på over 0,6 mg/kg lgv/dag (600 µg/kg), hvorfor dette vurderes ikke at ville indebære nogen sundhedsmæssig risiko.
From the above it is seen that none of the amounts being exposed to the consumer by toothbrushing, will result in a dose of more than 0.6 mg/kg bw/day (600 µg/kg bw/day), for which reason it is assessed not to involve any health risk.
1-Methyl-2-pyrrolidinon indebærer ingen sundhedsmæssig risiko ved indtagelse i de mængder, der er konstateret ved analyse af de udvalgte tandbørster.
1-Methyl-2-pyrrolidinone implies no health risks to the consumer by oral intake at the concentrations measured in the selected toothbrushes.
Naphthalen anvendes mest i produktionen af andre kemiske stoffer.
Naphthalene is used mostly in the production of other chemical substances.
Størsteparten anvendes til produktionen af phthalsyre anhydrid.
The major part is used in the manufacture of phthalic acid anhydride.
Naphthalen anvendes også i produktion af farvestoffer via mellemstofferne naphthol og naphthalen sulfonsyre.
Naphthalene is also used in the production of colorants via the intermediates naphthol and naphthalene sulphonic acid.
IUPAC navn Naphthalen CAS nr.
IUPAC name Naphthalene
Vandopløseligheden er 31 mg/l ved 25ºC (Budavari 1989).
The water solubility is 31 mg/l at 25ºC (Budavari 1989).
Fordelingskoefficienten log Kow er 3,4 (ECB 2003).
The partitioning coefficient n-octanol/water log Kow is 3.4 (ECB 2003).
Mulighed for kræftfremkaldende effekt
Possible risk of irreversible effects
67/548/EEC) og er derfor ikke med i Miljøministeriets bekendtgørelse om listen over farlige stoffer (Miljøministeriet 2002).
67/548/EEC) and therefore not yet included in the List of Dangerous Substances (Miljøministeriet 2002).
Samme klassificering er angivet i risikovurderingsrapporten (ECB 2003).
Same classification is stated in the risk assessment report (EC B 2003).
Naphthalen kan optages via alle eksponeringsveje (indånding, optagelse gennem huden og indtagelse).
Naphthalene can be taken up via all exposure routes (inhalation, percutaneous and by ingestion).