natgillin/translations-raw huggingface dataset:
Formic aldehyde, methanal, methylen oxid, metylaldehyd, oxymetylen, oxometan
Formic aldehyde, methanal, methylene oxide, methylaldehyde, oxymethylene, oxomethane
Klassificering iflg. listen over farlige stoffer (4).
Classification in accordance with the list of hazardous substances (4)
T; R23/24/25: Giftig ved indånding, ved hudkontakt og ved indtagelse.
T; R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
CARC3; R40: Mulighed for kræftfremkaldende effekt.
CARC3; R40: Limited evidence of a carcinogenic effect
R43: Kan give overfølsomhed ved kontakt med huden.
R43: May cause sensitization by skin contact.
Der er tilladt en maksimal mængde på 5 % i neglehærdere
A maximum amount of 5% in nail hardeners allowed
Molvægt (g/mol) Smeltepunkt,
No Observed (Adverse) Effect Level
3890 mm Hg ved 25° C (5)
3890 mm Hg at 25° C (5)
Oktanol/vand fordeling (log Kow)
Octanol/water partition coefficient (log Kow)
De toksiske effekter der er fundet efter eksponering af formaldehyd (ved inhalation) kan afhængig af dosis være slaphed, hovedpine, mavesmerter, besvimelse, angstfornemmelse, brændende følelse i næse og svælg, tørst, klam hud, påvirkning af centralnervesystemet, cyanosis, diarre, svimmelhed, irritation og nekrose i slimhinder og svælg, opkastning, kvalme, koma og chok (6).
The toxic effect observed after exposure of formaldehyde (by inhalation) may be, depending on dose, weakness, headache, abdominal pain, anaesthesia, anxiety, burning sensation in the nose and throat, thirst, clammy skin, central nervous system depression, cyanosis, diarrhoea, dizziness, irritation and necrosis of mucous membranes and gastrointestinal tract, vomiting, nausea, coma, and shock (6).
Indtagelse af vandige opløsninger kan forårsage nyreskader og føre til øget forekomst af format i urinen (6).
Ingestion of aqueous solutions of formaldehyde may cause renal injury and lead to an increase in formate levels in the urine (6).
Irritation og allergi
Skin irritation and sensitisation
Formaldehyd forårsager irritation i øjne, hud og slimhinder (3).
Formaldehyde is irritating to eyes, skin and mucosal membranes (3).
Ved standardiserede lappetest ses formaldehydkoncentrationer at forårsage hudirritation hos raske personer ved 2 % og højere (7).
With standard patch test protocols, formaldehyde concentrations of 2% and higher is observed to produce skin irritation in non-sensitised individuals (7).
Induktion af hudallergi er set ved eksponering for formaldehyd.
Induction of dermal sensitisation to formaldehyde has been observed after dermal exposure.
En induktionsgrænse er ikke klart fastsat, men den er estimeret til mindre end 5 % vandig opløsning (3).
A threshold for induction has not been clearly established, but it is estimated to be less than 5 % aqueous solution (3).
Forskellige studier har klassificeret formaldehyd som moderat til stærk allergifremkaldende (9,10,11).
Different studies has classified formaldehyde as a moderate to strong sensitizer (9,10,11).
I en undersøgelse (maksimization test) på marsvin blev der observeret kontaktallergi i 100 % af dyrene ved en formaldehydkoncentration på 2 % (7).
In an guinea pig maximization test sensitisation was observed in 100% of the animals at a formaldehyde concentration of 2% (7).
Allergi blev påvist ved en koncentration på 0,96 % formaldehyd (12).
Induction of sensitisation was observed at a concentration of 0.96% formaldehyde (12).
I en anden LLNA undersøgelse fremkaldte en formaldehydkoncentration på 0,4 % allergi (9).
In another LLNA test a formaldehyde concentration of 0.4 % induced sensitisation (9).
I en undersøgelse (serial dilution test) blev 8/35 formaldehyd-overfølsomme personer eliciteret med allergi ved den lavest testede koncentration (0,1 %) (7).
In a serial dilution test 8/35 formaldehyde-sensitised subjects developed allergy to the lowest concentration tested (0.1%) (7).
I et andet studie, sås få positive reaktioner ved koncentrationer under 0,1 % formaldehyd.
In another test, a few positive reactions were observed at concentrations below 0.1% formaldehyde.
Følgende responsfrekvenser blev observeret: 9/20 ved 0,5 %, 3/20 ved 0,1 %, 2/20 ved 0,05 %, and 1/20 ved 0,025 % (7).
The following response frequencies were observed: 9/20 at 0.5%, 3/20 at 0.1%, 2/20 at 0.05%, and 1/20 at 0.025% (7).
Læsioner hos forsøgsdyr sker typisk i næsen efter inhalation, i maven efter oral indtagelse og på huden efter dermal påføring.
The typical locations of lesions in experimental animals are the nose after inhalation, the stomach after oral administration and the skin after dermal application.
Læsionernes art afhænger af vævenes iboende evner til at respondere på skaden og af stoffets koncentration (3).
The nature of the lesions depends on the inherent abilities of the tissues involved to respond to the noxious event and on the local concentration of the substance (3).
Under et 2 års kronisk foderstudie i rotter blev der fundet en NOAEL på 15 mg/kg/dag.
In a 2 years chronic feeding study in rats a NOAEL of 15 mg/kg/day was obtained.
NOAEL var baseret på udvikling af læsioner i mavetarmkanalens slimhinde og histopatologiske ændringer i nyrerne efter indtagelse af formaldehyd via drikkevand (13).
The NOAEL was based on development of lesions of the gastric mucosa and histopathological changes in the kidneys after administration of formaldehyde via the drinking water (13).
En oral RfD
An oral RfD
Formaldehyd er genotoksisk i forskellige in vitro systemer (14,15,16).
Formaldehyde is genotoxic in different in vitro systems (14,15,16).
Der findes adskillige in vivo studier, der belyser formaldehyds mutagene potentiale.
Several in vivo studies are available on the mutagenic potential of formaldehyde.
er rapporteret for rotter og mus.
has been reported for rats and mice.
Den laveste TD50 blev fundet for rotter ved 1,35 mg/lgv/dag (17).
The lowest TD50 was found for rats at 1.35 mg/kg bw/day (17).
Baseret på denne værdi kan en acceptabel dosis sættes til 2,7 x 10
Based on this value, an acceptable dose may be estimated to 2.7 × 10
Dette livstidsrisiko er generelt accepteret.
This level of risk is generally accepted.
Der er ingen evidens for, at formaldehyd kan forårsage fosterskade eller kan påvirke reproduktionen ved inhalation (6).
There is no evidence that formaldehyde may induce teratogenicity or may affect reproduction by inhalation exposure (6).
Desuden er der udført en lang række humane lappetests.
Furthermore, a large number of human patch tests have been performed.
Det konkluderes af disse, at formaldehydkoncentrationer under 0,025 - 0,05 % sjældent fremkalder allergi hos formaldehyd-overfølsomme personer.
From these it is concluded that formaldehyde concentrations below 0.025 - 0.05% rarely elicitate sensitisation in formaldehyde-sensitised subject.
Derfor kan en koncentration på 0,01 % formaldehyd betragtes som en sikker koncentration, der omfatter både formaldehyd-overfølsomme personer og induktion af ikke-overfølsomme personer.
Therefore, a concentration of 0.01% formaldehyde may be considered as a safe concentration including both formaldehyde-sensitised subjects and the induction of non-sensitised subjects.
Der er sat en sikkerhedsfaktor på 100 for data fra LLNA undersøgelserne om ekstrapolering af data fra dyr til mennesker og ved at inkludere særligt følsomme menneskelige individer.
A safety factor of 100 is included for the data from LLNA tests for extrapolation of data from animals to humans and including of particularly sensitive human individuals.
En oral referencedosis (RfD) på 0,2 mg/kg lgv/dag er fastsat for formaldehyd baseret på en NOAEL på 15 mg/kg lgv/dag i rotter, der har indtaget formaldehyd via drikkevandet.
An oral Reference Dose (RfD) of 0.2 mg/kg bw/day is established for formaldehyde based on a NOAEL of 15 mg/kg bw/day in rats administrated formaldehyde by drinking water.
Virkningerne var reduceret øgning af legemsvægt og påvirkninger i mavetarmkanalen.
The effects were reduced body weight gain and effects in the gastro-intestinal tract.
Formaldehyd har et kræftfremkaldende potentiale.
Formaldehyde has a carcinogenic potential.
En acceptabel livstidsrisikodosis for cancer er vurderet til 2,7 x 10
An acceptable dose for lifetime risk of cancer has been estimated to 2.7 × 10
mg/kg/lgv/dag.
mg/kg bw/day.
Efter eksponering for denne dosis er der en risiko for cancer i 1 ud af 1 million eksponerede personer.
After exposure to this dose, there is a risk of cancer in 1 out of 1 million exposed persons.
Dette risikoniveau er generelt accepteret.
This risk level is generally accepted.
Tabel 6.1 Sammendrag af data for formaldehyd
Table 6.1 Summary of data for formaldehyde
NOAEL, indtagelse, rotte
NOAEL, intake, rat
Acceptabel dosis - livstids risiko, cancer
Acceptable dose - lifetime risk, cancer
Oral reference dosis (RfD)
Oral Reference Dose (RfD)
6.2 Sundhedsvurdering af stoffer i kunstige negle
6.2 Safety assessment of substances in artificial nails
2-Hydroxyethylakrylat er en farveløs væske med en sød, behagelig duft (5).
2-Hydroxyethyl acrylate is colourless liquid with a sweet pleasant odour (5).
2-Hydroxyethylakrylat er anført i positivlisten for monomerer og andre opstartsstoffer for plastik og emballage beregnet til kontakt med fødevarer.
2-Hydroxyethyl acrylate is included in the positive list of monomers and other starting substances for plastics and coatings intended to come into contact with foodstuffs.
Ethylenglycol, monoakrylat, hydroxyethylakrylat, 2-propenoic acid, 2hydroxyethyl ester
Ethylene glycol, monoacrylate, hydroxyethyl acrylate, 2-propenoic acid, 2-hydroxyethyl ester
T; R24: Giftig ved hudkontakt.
T; R24: Toxic in contact with skin
Studier om akut toksicitet hos 2-hydroxyethylakrylat angiver den orale LD50 værdi til at være 540 - 1070 mg/kg lgv.
Studies on the acute toxicity of 2-hydroxyethyl acrylate indicate oral LD50 values of 540 - 1070 mg/kg bw.
Ufortyndet materiale kan forårsage ætsning i mund, hals, og mavetarmkanalen (18).
Neat material may have caused chemically burns in the tissues of the mouth, throat, and gastrointestinal tract (18).
I akutte dermale toksikologiske studier blev der observeret LD50 værdier på 154 (kaniner, ufortyndet materiale) og >1000 mg/kg lgv (rotter, hjælpestof olivenolie).
Acute dermal toxicity studies showed LD50 values of 154 (rabbits, undiluted material) and >1000 mg/kg bw (rats, vehicle olive oil).
Ved høje koncentrationer blev reduceret øjenlågsfarve, reduceret hornhinde refleks, tab af evne til at rejse sig og muskelkoordinering observeret (18).
At high concentrations decreased eyelid tone, decreased corneal reflex, loss of righting reflex and muscle coordination were noted (18).
Akutte inhalationsstudier, hvor rotter blev eksponeret for 333 til 394 ppm (≈ 1580 - 1870 mg/m
Acute inhalation data indicate that exposures of rats to 333 to 394 ppm (≈ 1580 - 1870 mg/m
Disse data indikerer at 2-hydroxyethylakrylat er moderat akut toksisk.
These data indicate that 2-hydroxyethyl acrylate is moderately acute toxic.
2-Hydroxyethylakrylat virker meget irriterende på huden (5,18).
2-Hydroxyethyl acrylate is severely irritating to the skin (5,18).
Flere studier har vist, at ufortyndet 2-hydroxyethylakrylat virker meget irriterende på huden, hvis stoffet er i kontakt med huden tilstrækkeligt længe (18).
Several studies have shown that undiluted 2-hydroxyethyl acrylate is severely irritating to the skin if left in contact with the skin for a sufficient period of time (18).
Ved øjenkontakt kan 2-hydroxyethylakrylat forårsage alvorlig irritation og forvolde uigenkaldelig skade på hornhinden (18).
Upon eye contact, 2-hydroxyethyl acrylate may cause severe irritation with irreversible corneal injury (18).
Allergistudier på dyr og mennesker viser, at 2-hydroxyethylakrylat er et allergen og kan krydsreagere med andre akrylater.
Skin sensitization studies in animals and humans indicate that 2-hydroxyethyl acrylate is a sensitizer and may cross-react with other acrylates in some exposed individuals.
2-Hydroxyethylakrylat er fundet allergifremkaldende i både LLNA tests, Buehler tests og maximazation tests i marsvin; dog er nogle af studierne af ældre dato (1970-1995) (18).
2-Hydroxyethyl acrylate has been found to be a sensitizer in both local Lymph Node Assays (LLNA), Buehler tests and maximization tests in guinea pigs; however some of the studies being of older date (19701995) (18).
Tolv akrylat-overfølsomme patienter blev testet med forskellige stoffer inklusive 2-hydroxyethylakrylat i en lappetest.
Twelve acrylate-sensitised patients were tested with various substances including 2-hydroxyethyl acrylate in a patch test.
Ti af tolv patienter viste positive reaktioner over for 2-hydroxyethylakrylat, når de blev testet med en koncentration på 0,1 % (20).
Ten out of twelve patients had a positive reaction to 2-hydroxyethyl acrylate when tested at a concentration of 0.1% (20).
I en anden human lappetest med akrylatoverfølsomme testpersoner reagerede 8 % positivt over for 2hydroxyethylakrylat i en koncentration på 0,1 % (21).
In another human patch test with acrylatesensitised subjects 8% of the test persons reacted positive to 2-hydroxyethyl acrylate in a 0.1% concentration (21).
På grundlag af disse studier vurderes 2-hydroxyethylakrylat at have et moderat potentiale for at fremkalde allergi hos akrylat-overfølsomme individer.
Based on these studies 2-hydroxyethyl acrylate is evaluated to have a moderate potential to elicitate sensitisation in acrylate-sensitised subjects.
Toksicitet ved gentagen eller længerevarende eksponering Gentagen eksponering for 2-hydroxyethylakrylat (0, 5, 10, 25 ppm ≈ 0, 24, 48, 119 mg/m
Toxicity from repeated or prolonged exposure Repeated exposures to vapours of 2-hydroxyethyl acrylate (0, 5, 10, 25 ppm ≈ 0, 24, 48, 119 mg/m
3) af rotter via inhalation (7 t/dag, 5 dage/uge i fire uger) forårsagede alvorlig nasal irritation som medførte død på grund af svigtende åndedræt ved højere koncentrationer.
3) to rats via inhalation (7 hr/day, 5 days/week for four weeks) caused severe nasal irritation, resulting in death due to respiratory failure at higher concentrations.
I et mg/m andet studie var effekten på forsøgsrotter efter 18 måneders eksponering for 5 ppm 2-hydroxyethylakrylat irritation af åndedrætsorganerne, uden signifikant tegn på systemisk toksicitet (18).
In another study the effects observed following 18 months exposure of laboratory rats to 5 ppm of 2-hydroxyethyl acrylate were related to irritation of the respiratory tract, without significant evidence of systemic toxicity (18).
Foderstudier med rotter og hunde har vist, at 2-hydroxyethylakrylat har lav toksicitet efter gentagen dosering via denne rute.
Dietary studies with rats and dogs have shown that 2-hydroxyethyl acrylate has a low toxicity after repeated dosing via this route.
Der blev ikke påvist effekter ved den højest testede dosis op til 131 mg/kg/lgv i foderet.
No effects were observed in the highest tested dose up to 131 mg/kg bw/day.
En NOAEL på 131 mg/kg/lgv blev fastsat hos hunde, der blev fodret med op til 131mg/kg lgv i deres foder (18).
A NOAEL of 131 mg/kg bw/day was established in dogs fed up to 131 mg/kg bw in their diet (18).
2-Hydroxyethylakrylat havde ikke mutagen effekt på S.typhimurium (bakteriel reverse mutation assay) in vitro med eller uden metabolisk aktivering, men var positiv med metabolisk aktivering hvis testet med to E.coli stammer.
2-Hydroxyethyl acrylate was not mutagenic to S. typhimurium (bacterial reverse mutation assay) in vitro with or without metabolic activation but was positive with metabolic activation when tested with two E. coli strains.
Der blev ikke set kromosomskader i et 18-måneders inhalationsstudie.
No evidence of chromosomal damage was seen in an 18-month inhalation study.
Fire rotter pr. køn pr. gruppe blev aflivet efter eksponering i 12 måneder og benmarvsceller blev undersøgt for kromosomskader.
Four rats pr. sex pr. group were killed after 12-months exposure and the bone marrow cells examined for chromosomal damage.
Ingen effekter blev observeret (18).
No effects were observed (18).
Der blev ikke observeret carcinogene effekter i et kronisk toksicitet/oncogenicititets studie, der blev foretaget med indånding som eksponeringsrute (18).
No evidence of a carcinogenic effect was observed in a chronic toxicity/oncogenicity study conducted by the inhalation route of exposure (18).
Histopatologiske undersøgelser af rotters reproduktionsorganer i et 18måneders inhalationsstudie viste en øgning af aldersrelaterede læsioner (fibrinoid nedbrydning af sædstrengene) og betændelse i uterus (uden andre associerede histopatologiske effekter).
Histopathological examination of the reproductive organs of rats from an 18month inhalation study revealed an increase in age-related lesion (fibrinoid degeneration in the vascular channels of the testes) and uterine inflammation (without any other associated histopathological effects).
De fundne effekter blev vurderet ikke at være behandlingsrelaterede og ikke skadelig for reproduktionen (18).
Neither effects were considered treatment-related or adverse to reproduction (18).
Indtagelse af 2-hydroxyethylakrylat via foderet hos rotter eller hunde resulterede ikke i behandlingsrelaterede effekter på testikelvægt eller histopatologiske ændringer i testikler eller uterus (18).
Dietary administration of 2-hydroxyethyl acrylate to rats or dogs did not result in treatment-related effects on testicular weight or histopathology of the testes or uterus (18).
2-Hydroxyethylakrylats kritiske effekter er dets potentiale til at kunne inducere og elicitere irritation og kontaktallergi.
The critical effect of 2-hydroxyethyl acrylate is its potential to induce and elicitate irritation and sensitisation.
Der blev ikke fundet en nedre sikker dosis for kontaktallergi, men der blev fundet elicitering af allergi ved en koncentration på 0,1 %.
No lower dose has been established for sensitisation, but elicitation of allergy was observed at a concentration of 0.1%.
Baseret på tilgængelige studier med 2hydroxyethylakrylat vurderes det, at stoffet har et moderat potentiale til at kunne inducere kontaktallergi.
Based on the available studies on 2-hydroxyethyl acrylate it is evaluated that the substance has a moderate potential to induce sensitisation.
Tabel 6.2 Sammenfatning af data for 2-hydroxethylakrylat
Table 6.2 Summary of data for 2-hydroxethyl acrylate
NOEL, (mg/kg lgv), oral, hund
NOEL, (mg/kg bw), oral, dog
2-Hydroxypropylakrylat (HPA) er en klar til let gul væske med en sød lugt (22).
2-Hydroxypropyl acrylate (HPA) is a clear to light yellow liquid with a sweet odour (22).
Der er kun fundet begrænsede data på 2-hydroxypropylakrylat.
Only limited data has been identified on 2-hydroxypropyl acrylate.
Imidlertid blev der fundet data på hydroxypropylakrylat (CAS nr. 25584-83-2).
However, data was found on hydroxypropyl acrylate (CAS no. 25584-83-2).
Nedenfor anvendes de toksikologiske data for dette produkt også til at beskrive 2-hydroxypropylakrylats toksicitet.
Below, data on toxicology for this commercial product is also used to describe the toxicity of 2-hydroxypropyl acrylate.
1,2-Propanediol, 1-akrylat, propylenglycol monoakrylat, beta-hydroxypropylakrylat
1,2-Propanediol, 1-acrylate, propylene glycol monoacrylate, beta-hydroxypropyl acrylate
2-Hydroxypropylakrylat har moderat til lav toksicitet efter oral eksponering.
2-Hydroxypropyl acrylate is of moderate to low toxicity after oral exposure.
LD50 værdier for rotter ved oral eksponering var 250 til 500 mg/kg lgv med rapporterede værdier så høje som 590 til 1300 mg/kg lgv.
The rat oral LD50 was 250 to 500 mg/kg bw with reports of values as high as 590 to 1300 mg/kg bw.
Musens orale LD50 værdi var 1060 mg/kg lgv (22).
The mouse oral LD50 value was 1060 mg/kg bw (22).
LD50 værdier hos kaniner efter lokal applikation varierer fra 170 mg/kg lgv til 250 mg/kg lgv.
LD50 values in rabbits after topical application range from 170 mg/kg bw to 250 mg/kg bw.
Dyrene, der overlevede, udviklede moderat ødem, moderat til alvorlig necrose og lokale tegn på irritation på applikationsstedet (22).
The animals that survived developed moderate oedema, moderate to severe necrosis, and local evidence of irritation at the application site (22).
2-Hydroxypropylakrylat virker irriterende på øjne, næse og åndedrætsorganer (22).
2-Hydroxypropyl acrylate is irritating to the eyes, nasal and respiratory organs (22).
Hydroxypropylakrylat virker meget irriterende på huden (23).
Hydroxypropyl acrylate is highly irritating to the skin (23).
Allergistudier på dyr og mennesker viser, at hydroxypropylakrylat er allergifremkaldende og vil krydsreagere med andre akrylater.
Skin sensitization studies in animals and humans indicate that hydroxypropyl acrylate is likely to be a sensitizer and will cross-react with other acrylates in some exposed individuals.
I marsvin er 2hydroxypropylakrylat et af de mere potente sensibiliserende stoffer (22).
2-Hydroxypropyl acrylate is among the more potent sensitisers in guinea pigs (22).
Ni patienter, der var akrylat-overfølsomme blev i en lappetest testet med forskellige stoffer heriblandt 2-hydroxypropylakrylat.
Nine acrylate-sensitised patients were tested with various substances including 2-hydroxypropyl acrylate in a patch test.
Syv ud af ni patienter reagerede positivt over for 2-hydroxypropylakrylat i en koncentration på 0,1 %, hvilket indikerer et potentiale for kontaktallergi (20).
Seven out of nine patients had a positive reaction to 2-hydroxypropyl acrylate tested in a concentration of 0.1% indicating a sensitisation potential (20).
Det vurderes på basis af humane og dyredata, at 2-hydroxypropylakrylat har et moderat potentiale for at elicitere og inducere allergi.
It is evaluated based on human and animal data that 2-hydroxypropyl acrylate has a moderate potential to elicitate and induce allergy.
Toksicitet ved gentagen eller længerevarende eksponering Rotters, mus', kaniners og hundes gentagen eksponering for dampe af hydroxypropylakrylat (6 t/dag, 5 dage/uge i 21 eller 20 eksponeringer) resulterede i alvorlig irritation af de øvre åndedrætsorganer med døden til følge.
Toxicity from repeated or prolonged exposure Repeated exposure to vapours of hydroxypropyl acrylate (6 hr/day, 5 days/week for 21 or 20 exposures to rats and mice and rabbits and dogs, respectively) did result in severe irritation of the upper respiratory tract, resulting in death due to respiratory failure at higher concentrations and concentration-related local irritation at sub-lethal exposures.
Systemisk toksicitet blev ikke observeret (23).
systemic toxicity was observed (23).
2-hydroxypropylakrylat var ikke mutagent i et in vivo mikronucleus studie med mus (23).
2-Hydroxypropyl acrylate was not mutagenic in an in vivo mouse micronucleus study (23).
Hydroxypropylakrylat var ikke mutagent i S.typhimurium (bakteriel reverse mutation studie) in vitro med eller uden metabolisk aktivering, men var positiv med metabolisk aktivering, hvis testet med to E.coli stammer.
Hydroxypropyl acrylate was not mutagenic to S. typhimurium (bacterial reverse mutation assay) in vitro with or without metabolic activation but was positive with metabolic activation when tested with two E. coli strains.
Hydroxypropylakrylat var negativ i et genmutationsforsøg udført med pattedyrsceller in vitro, men udviste clastogenisk aktivitet i cytogen og kromosom aberration forsøg.
In mammalian cells in vitro, hydroxypropyl acrylate was negative in a gene mutation assay but had clastogenic activity in cytogenetic and chromosomal aberration assays.
I disse pattedyrscelle forsøg, var der kun positive resultater ved koncentrationer, der resulterede i signifikant celledød.
In these mammalian cell assays, positive results occurred only at concentrations that resulted in significant cell death.
Derfor vurderes de positive resultater at være tvivlsomme.
Thus, the positive results are considered equivocal.
Hydroxypropylakrylat var ikke mutagent i en in vivo muse mikronucleus test (23).
Hydroxypropyl acrylate was not mutagenic in an in vivo mouse micronucleus study (23).
Carcinogenicitet Der er ingen data fundet.
Carcinogenicity No data found