SEC Contract Filing

Filing Date: 2024-08-14

Document Content:
<DOCUMENT>
<TYPE>EX-10.1
<SEQUENCE>2
<FILENAME>ea021067201ex10-1_unicycive.htm
<DESCRIPTION>MANUFACTURING AND SUPPLY AGREEMENT DATED AS OF OCTOBER 31, 2020 BY AND BETWEEN UNICYCIVE THERAPEUTICS, INC. AND SHILPA MEDICARE LTD
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: right; text-indent: 0pt"><B>Exhibit 10.1</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-indent: 0pt; margin: 0pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; width: 100%"><TR STYLE="vertical-align: top; text-align: justify">
<TD STYLE="width: 0.25in; text-align: left"><FONT STYLE="font-size: 10pt">[*]</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt">Certain information in this
document has been omitted from this exhibit because it is both (i) not material and (ii) would be competitively harmful if publicly disclosed.</FONT></TD>
</TR></TABLE>
<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="text-indent: 0pt; font: bold 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: center">MANUFACTURING AND SUPPLY
AGREEMENT</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; text-indent: 0pt; margin: 0pt; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify; text-indent: 0.5in">This Manufacturing
and Supply Agreement, effective as of 31<SUP>st</SUP> October 2020 (the &ldquo;Effective Date&rdquo;), is entered into by and between <B>Unicycive
Therapeutics Inc., </B>a Delaware corporation having offices at 5150 El Camino Real, Suite A-32, Los Altos, CA 94022 (&ldquo;Unicycive&rdquo;),
and <B>Shilpa Medicare Ltd., </B>an India corporation having offices at # 12-6-214/ A I, Hyderabad Road, Raichur - 584 135, Karnataka,
India (&ldquo;Shilpa&rdquo;).</P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="text-indent: 0pt; font: bold 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: center"><FONT STYLE="text-decoration: none">RECITALS</FONT></P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify; text-indent: 0.5in"><B>WHEREAS,
</B>UNICYCIVE owns or otherwise controls all current proprietary information, intellectual property rights and technology relating to
the drug known as Renazorb, a description of and information relating to which is set forth in <U>Exhibit A</U> of this Agreement (&ldquo;Renazorb&rdquo;);
and</P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify; text-indent: 0.5in"><B>WHEREAS,
</B>UNICYCIVE wishes Shilpa to provide, and Shilpa has agreed to provide, pursuant to the terms and conditions set forth in this Agreement,
certain development, manufacturing, supply and other CMC-related services related to the development and commercialization of Renazorb,</P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify; text-indent: 0.5in"><B>THEREFORE, </B>UNICYCIVE and Shilpa hereby agree as follows:</P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify; text-indent: 0in"><B>1.<FONT STYLE="font-family: Times New Roman, Times, Serif"> </FONT>Definitions. </B>When
used in this Agreement the capitalized terms listed in this Section 1 shall have the following meanings:</P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify; text-indent: 0.5in">1.1<FONT STYLE="font-family: Times New Roman, Times, Serif">
</FONT>&ldquo;<U>Affiliate</U>&rdquo; means any entity controlling, controlled by or under common control with a party to this Agreement.
For purposes of this definition, the term &ldquo;control&rdquo; shall mean the direct or indirect beneficial ownership of 50% or more of
the voting or income interest in such entity.</P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify; text-indent: 0.5in">1.2<FONT STYLE="font-family: Times New Roman, Times, Serif">
</FONT>&ldquo;<U>Agreement</U>&rdquo; means this Manufacturing and Supply Agreement, including any exhibits or schedules hereto, as such
may be amended from time to time, in writing, by mutual agreement of the parties.</P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify; text-indent: 0.5in">1.3<FONT STYLE="font-family: Times New Roman, Times, Serif">
</FONT>&ldquo;<U>Certificate of Analysis</U>&rdquo; means a certificate provided by Shilpa or a Third-Party Manufacturer for each Renazorb
Shipment, certifying that the Renazorb Shipment meets all applicable Legal Requirements and the Renazorb Specifications.</P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt; text-align: justify; text-indent: 0.5in">1.4
&ldquo;<U>Delivery Date</U>&rdquo; shall have the meaning specified in Section 7.</P>

<P STYLE="text-indent: 0pt; font: 10pt Times New Roman, Times, Serif; margin: 0pt">&nbsp;</P>

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