SEC Contract Filing

Filing Date: 2017-02-28

Document Content:
<DOCUMENT>
<TYPE>EX-10.16
<SEQUENCE>3
<FILENAME>tsro-20161231ex10168b5ed.htm
<DESCRIPTION>EX-10.16
<TEXT>
<!--HTML document created with Merrill Bridge 6.4.50.0-->
<!--Created on: 2/28/2017 3:39:19 PM-->
<html>
	<head>
 <title>
 tsro_Ex10_16
 </title>
	</head>
	<body><div style="margin-left:11.7647058823529%;margin-right:11.7647058823529%;"><div style="width:100%">

 <p style="margin:0pt;text-align:right;line-height:100%;font-family:Calibri;font-size: 12pt;">

 <font style="display:inline;font-family:Times New Roman,Times,serif;font-weight:bold;font-size:12pt;">Exhibit 10.16</font>

 </p>

 <p style="margin:0pt;text-align:right;line-height:100%;font-family:Calibri;font-size: 11pt;">

 &nbsp;

 </p>

</div></div><div style="margin-left:11.7647058823529%;margin-right:11.7647058823529%;">
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;text-align:center;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">TESARO,&nbsp;INC.</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;text-align:center;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">1000 Winter Street, Suite&nbsp;3300</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;text-align:center;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">Waltham, Massachusetts 02451</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;text-align:center;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">&nbsp;</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;font-size:12pt;">February 23, 2017</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">&nbsp;</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">Mary Lynne Hedley, Ph.D.</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">President and Chief Operating Officer</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">TESARO,&nbsp;Inc.</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">1000 Winter Street, Suite&nbsp;3300</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">Waltham, Massachusetts 02451</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">&nbsp;</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">Dear Mary Lynne:</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">&nbsp;</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;text-indent:36pt;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">On behalf of TESARO,&nbsp;Inc. (the &#x201C;</font><font style="display:inline;font-family:Times New Roman,Times,serif;font-weight:bold;color:#000000;font-size:12pt;">Company</font><font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">&#x201D;),&nbsp;I am very pleased to offer you an amended and restated employment letter in connection with your ongoing employment in the position of President and Chief Operating Officer.</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:100%;text-indent:36pt;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">&nbsp;</font>
 </p>
 <p style="margin:0pt 0pt 0pt 36pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">The terms of your position with the Company are as set forth below:</font>
 </p>
 <p style="margin:0pt 0pt 0pt 36pt;background-color: #FFFFFF;line-height:100%;color:#000000;font-family:Calibri;font-size: 12pt;">
 <font style="display:inline;font-family:Times New Roman,Times,serif;color:#000000;font-size:12pt;">&nbsp;</font>
 </p>
 <p style="margin:0pt;background-color: #FFFFFF;line-height:13pt;text-indent:36pt;c