SEC Contract Filing

Filing Date: 2021-05-13

Document Content:
<DOCUMENT>
<TYPE>EX-10.4
<SEQUENCE>3
<FILENAME>rlay-ex104_188.htm
<DESCRIPTION>EX-10.4
<TEXT>
<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/html4/loose.dtd">
<html>
<head>
<title>
rlay-ex104_188.htm
</title>
</head>
<!-- NG Converter v5.0.2.50 -->
<body>

<p style="text-align:right;margin-bottom:0pt;margin-top:0pt;text-indent:0%;font-weight:bold;font-size:10pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Exhibit 10.4 </p>
<p style="text-align:justify;margin-bottom:0pt;margin-top:0pt;text-indent:0%;font-size:8pt;">&nbsp;</p>
<p style="text-align:center;margin-bottom:12pt;margin-top:0pt;text-indent:0%;font-weight:bold;font-size:12pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">AMENDMENT NO. AR2 TO </p>
<p style="text-align:center;margin-bottom:12pt;margin-top:0pt;text-indent:0%;font-weight:bold;font-size:12pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">AMENDED AND RESTATED COLLABORATION AND LICENSE AGREEMENT</p>
<p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.69%;font-size:12pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">This Amendment No. AR2 to the Amended and Restated Collaboration and License Agreement (the &#8220;<font style="text-decoration:underline;">Amendment No. AR2</font>&#8221;), effective as of May 12, 2021 (the &#8220;<font style="text-decoration:underline;">Amendment No. AR2 Effective Date</font>&#8221;), is by and between <font style="font-weight:bold;">D.&#160;E.&#160;Shaw Research, LLC</font>, a Delaware limited liability company located at 120 West 45<sup style="font-size:85%;line-height:120%;vertical-align:top">th</sup> Street, 39<sup style="font-size:85%;line-height:120%;vertical-align:top">th</sup> Floor, New York, NY 10036 (&#8220;<font style="text-decoration:underline;">DESRES</font>&#8221;), and <font style="font-weight:bold;">Relay Therapeutics, Inc.</font>, a Delaware corporation located at 399 Binney Street, Cambridge, MA 02139 (&#8220;<font style="text-decoration:underline;">Company</font>&#8221;).&nbsp;&nbsp;DESRES and Company are each sometimes referred to herein as a &#8220;<font style="text-decoration:underline;">Party</font>&#8221; or collectively as the &#8220;<font style="text-decoration:underline;">Parties</font>&#8221;.</p>
<p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.69%;font-family:Times New Roman;font-size:11pt;">&nbsp;</p>
<p style="margin-bottom:12pt;margin-top:0pt;text-indent:7.69%;color:#000000;font-size:12pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;"><a name="_Hlk12622680"></a>WHEREAS, DESRES and Company are parties to the Amended and Restated <font style="color:#000000;">Collaboration and License Agr</font>eement, effective as of June 15, 2020, as amended by Amendment No. AR1 effective as of February 4, 2021 (collectively, the &#8220;<font style="text-decoration:underline;">Agreement</font>&#8221;); </p>
<p style="margin-bottom:12pt;margin-top:0pt;text-indent:7.69%;color:#000000;font-size:12pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;"><a name="_cp_text_1_1"></a><a name="_cp_text_4_7"></a><a name="_Hlk11324435"></a><a name="_cp_text_4_8"></a><a name="_cp_text_4_7"></a>WHEREAS, the Parties <a name="_Hlk11324435"></a>desire to increase the Annual Collaboration Fee <a name="_cp_text_4_8"></a>by mutual agreement, as set forth below;</p>
<div align="left">
<table border="0" cellspacing="0" cellpadding="0" style="border-collapse:collapse; width:100%;">
<tr>
<td valign="top" style="width:3.85%;white-space:nowrap">
<p style="margin-bottom:12pt;margin-top:0pt;text-indent:3.85%;font-size:12pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;"></p></td>
<td valign="top">
<p style="margin-bottom:12pt;margin-top:0pt;text-indent:3.85%;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;font-family:Times New Roman;font-size:12pt;"><a name="_cp_text_2_14"></a><a name="_cp_text_2_15"></a><a name="_cp_text_2_25"></a><a name="_cp_text_2_27"></a>NOW THEREFORE, the Parties agree, in accordance with Section 17.4 of the Agreement, as follows:</p></td></tr></table></div>
<p style="margin-bottom:0pt;margin-top:0pt;margin-left:15.38%;text-indent:0%;font-family:Times New Roman;font-size:11pt;"><a name="_cp_text_2_35"></a><a name="_cp_blt_2_37"></a><a name="_cp_blt_1_40"></a><a name="_cp_blt_2_39"></a><a name="_cp_blt_1_42"></a><a name="_cp_blt_2_41"></a>&nbsp;</p>
<div align="left">
<table border="0" cellspacing="0" cellpadding="0" style="border-collapse:collapse; width:100%;">
<tr>
<td valign="top" style="width:7.69%;white-space:nowrap">
<p style="text-align:left;margin-bottom:12pt;margin-top:0pt;font-weight:bold;font-style:normal;color:#auto;font-size:12pt;font-family:Times New Roman;text-transform:none;font-variant: normal;letter-spacing:0pt;"><font style="font-weight:bold;font-style:normal;text-decoration:none;Background-color:#auto;color:#auto;font-size:12pt;font-family:Times New Roman;text-transform:none;font-variant: normal;letter-spacing:0pt;">1.</font></p></td>
<td valign="top">
<p style="text-align:left;margin-bottom:12pt;margin-top:0pt;font-weight:bold;font-style:normal;color:#auto;text-transform:none;font-variant: normal;letter-spacing:0pt;font-family:Times New Roman;font-size:12pt;"><font style="Background-color:#auto;text-decoration:none;"></font><font style="font-weight:normal;color:#000000;"></font><font style="color:#000000;font-weight:normal;">Section 5.1 of the Agreement is hereby deleted in its entirety and replaced as follows:</font></p></td></tr></table></div>
<p style="text-align:left;margin-bottom:12pt;margin-top:0pt;margin-left:7.69%;color:#000000;font-size:12pt;font-family:Times New