Word: metastasize Part of Speech: verb Etymology: From metastasis + -ize (suffix forming verbs meaning to do things denoted by the adjectives or nouns the suffix is attached to). Metastasis is a learned borrowing from Late Latin metastasis (“(rhetoric) rapid or sudden transition from one argument, point, or topic to another”), and from its etymons Koine Greek μετάστασις (metástasis, “(rhetoric) rapid or sudden transition from one argument, point, or topic to another”) and Ancient Greek μετάστασις (metástasis, “change; removal; (medicine) movement of disease, pain, etc., from one part of the body to another”), from μετᾰ- (metă-, prefix denoting change in condition or position) (possibly ultimately from Proto-Indo-European *meth₂) + στᾰ́σῐς (stắsĭs, “condition, state; position”) (ultimately from Proto-Indo-European *steh₂- (“to stand (up)”)), modelled after μεθιστάναι (methistánai, “to change; to remove”). The use of French métastase (“metastasis”) to refer to the spread of cancer was coined in 1829 by the French gynecologist Joseph Récamier (1774–1852). Pronunciation: /mɪˈtæstəsaɪz/, /məˈtæstəˌsaɪz/ 1. Of a disease (especially cancer) or a tumour: to form a metastasis (“a secondary focus away from the primary site”) in (a body organ). Labels: British, English, Oxford, US, specifically, transitive Example: "I remember the first time he woke up throwing up, and my first thought wasn't, 'Oh he has the stomach flu,'" she [Rene McNall-Knapp] said. "It was, 'Oh, it's gone to his brain, and it's metastasized his brain, and he's throwing up because of that.'" 2. To disseminate or spread (something, often an undesirable thing), especially in a destructive manner. Labels: British, English, Oxford, US, figuratively, transitive Example: In a broader sense, criticism as a form is in trouble. And celebrities like [Ariana] Grande, like [Michael] Che, like [Olivia] Munn, who swat at it to the delight of their fans, concerningly seem to metastasize the problem. 3. Of a disease (especially cancer) or a tumour: to undergo metastasis (“spreading from a primary site to one or more other sites in the body”). Labels: British, English, Oxford, US, intransitive, specifically Example: On other screens are closeups of skin pores, before and after, details of regimes for everything, your hands, your neck, your thighs. Your elbows, especially your elbows: aging begins at the elbows and metastasizes. Example: Your lump could be a secondary cancer metastasized from the bowel. I had a patient like that not long ago. 4. Of a thing, often one which is undesirable: to disseminate or spread, especially in a destructive manner. Labels: British, English, Oxford, US, figuratively, intransitive Example: Late last month, a conservative website called The Federalist published an article advocating that healthy, young Americans deliberately infect themselves with Covid-19, […] If enough Americans expose themselves to the virus and become immune, the theory goes, the country would have a mobilized cadre of immune citizens. […] The article was widely discredited by public health experts and economists, as both logically dubious and ethically specious, but such thinking has already metastasized.