Species 8472 bio - ship The Species 8472 bio - ship was a type of organic starship used by Species 8472 in large numbers during their invasion of the Milky Way Galaxy in 2373 . ( ) History . In 2373 , the Borg provoked a war with Species 8472 by invading fluidic space . Species 8472 defeated the Borg and launched their own counter - invasion of the Milky Way , sending hundreds of bio - ships through a string of quantum singularities in a region of space later nicknamed the " Northwest Passage " . Near the end of that year , the discovered a single regenerating bio - ship amongst the debris of 15 Borg cube s . The ship fired on " Voyager " , knocking it off - course before " Voyager " escaped . Many more bio - ships were detected as " Voyager " traveled deeper into Borg space . ( ) After forging an alliance with the Borg , the " Voyager " crew developed nanoprobe - based bio - molecular warhead s effective against Species 8472 . Seven of Nine then took " Voyager " into fluidic space to force a confrontation ; " Voyager " successfully destroyed four bio - ships within fluidic space , and thirteen more after it returned to normal space . Faced with this weapon , the remaining bio - ships retreated to fluidic space en masse . ( ) One damaged bio - ship was left behind in the Delta Quadrant . It was chased by a Hirogen hunting party for six months and eventually abandoned by its pilot above an asteroid . ( ) Technical data . A bio - ship was composed of genetically similar organic material to Species 8472 and thus shared their resistance to technology and weakness to modified nanoprobes . The ship was highly resistant to conventional weaponry and could regenerate itself if damaged . The hull was also impervious to sensor s and tractor beam s . Each bio - ship was piloted by a single individual . Bio - ships were armed with a single forward - mounted directed energy weapon powerful enough to destroy Borg cubes with a few shots . Eight bio - ships , directing their firepower into an energy focusing ship , were capable of destroying a planet . Equipped with an antimatter - based warp propulsion system , the ship could operate both in its native medium of fluidic space and in the vacuum of normal space , and open quantum singularities to pass between the two . When in flight , the three fins on the bio - ship ' s rear section were extended . Internally , the bio - ship had structures resembling flesh and bones . There was a network of organic conduit s that carried electrodynamic fluid , possibly as an energy source , as well as a binary matrix laced with neuropeptide s that may have functioned as a computer . The bio - ship could dock to another vessel by " dissolving " through to its interior . ( ) Appendices . Background information . The Species 8472 bio - ships were created as a CGI model built by Foundation Imaging ' s senior supervising visual effects animator , Adam " Mojo " Lebowitz . Their two forms of weaponry were devised by Visual Effects Supervisor Ronald B . Moore and Visual Effects Coordinator Cheryl Gluckstern . ( " Cinefantastique " , Vol . 29 , No . 6 / 7 , p . 95 ) The bio - ship was featured in the of the VOY Season 6 DVD . However , Species 8472 does not appear in the sixth season of " Voyager " . Apocrypha . In " Star Trek Online " , this ship is identified as a " Nicor " - class cruiser .