Mutation Mutation was a biological change outside that of normal evolution , be it forced or effected by outside sources to bring a change which would not normally have occurred in the same time frame or along a particular path of evolution . Something was said to be mutagenic if it caused mutation . Process . Some reasons for mutation were similar to that of evolution — the adaption to a situation , area , or time ; however it was a forced and " unnatural " change , outside of what of would have occurred during " normal " evolution . Other mutations were caused by accident or by deliberate design of another individual or species . Mutations could be caused by deliberate subjection to a mutagenic process , ( TV : " Genesis of the Daleks " ) by exposure to radiation , ( TV : " The Ambush " , " The Ark " , PROSE : " The Sons of the Crab " ) by exposure to DNA or toxins from another species , ( PROSE : " The Weeping " , TV : " Cold Blood " ) or by other means . Examples . According to one account , the Dalek s were created by Davros mutating the Kaled race by subjecting them ( or their cells ) to a mutagenic process , forcing them to evolve from the effect of radiation . ( TV : " Genesis of the Daleks " ) According to another account , the surviving Dal s and Thal s of a neutronic war involving atomic weapon s mutated in the war , the Dals being the " forebear " to the creature inside the Daleks ' armour . ( TV : " The Ambush " ) Many mutants also lived in the Lake of Mutations on Skaro . According to Ganatus , the creatures in the lake were bred and crossbred until the original species had " long been replaced " . ( TV : " The Expedition " ) According to a definition by the Movellan s , Davros himself was a humanoid mutant . ( TV : " Destiny of the Daleks " ) The Refusian s ' invisibility was a result of a mutation caused by solar flare s on their planet Refusis II . ( TV : " The Ark " ) The spiders of Metebelis III mutated , becoming highly intelligent and having great psycho - kinetic / telepathic powers as a result of mutation from the Metebelis or " blue " crystal . ( TV : " Planet of the Spiders " ) The Primord s came into existence during an attempt to penetrate the Earth ' s crust , when humans came into physical contact with Stahlman ' s ooze . This mutated them into the animalistic Primords which favoured heat like that provided by the Stahlman ' s ooze . ( TV : " Inferno " ) Although the physical changes of the Solonian s were believed by the humans of the Earth Empire to be harmful mutations , they were actually part of the species ' natural life cycle , where seasonal metamorphosis occurred . ( TV : " The Mutants " ) Mawdryn and his followers stole a metamorphic symbiosis regenerator from the Time Lord s and used it on themselves , only to find that their immortality was one of unending mutation and regeneration . ( TV : " Mawdryn Undead " ) The entire colonist population of Agelaos was mutated by the millions of types of alien DNA filtering through the wormhole above the planet . ( PROSE : " The Weeping " ) Silurian venom sometimes had mutagenic properties , as when Alaya poisoned Tony Mack . ( TV : " Cold Blood " ) The Yend underwent severe mutations after exposure to radiation from the star Mortain . ( PROSE : " The Sons of the Crab " ) On one planet , a crashed spacecraft spilled fuel . This caused nearby insect s and other life forms to mutate to giant sizes . ( COMIC : " The Mutants " ) Exposure to zygma energy , employed in the functioning of the time cabinet , caused mutations on its only known user , Magnus Greel . ( TV : " The Talons of Weng - Chiang " ) The Time Lord s became what they were through billions of years of exposure to the Untempered Schism . Similarly , Melody Pond was mutated in utero by being conceived in the TARDIS as it was flying through the time vortex . ( TV : " A Good Man Goes to War " ) Saibra , a woman who identified as " mutant human " , had a condition which enabled her to change form by replicating living cells upon contact . She was given a gene suppressant to control her condition by the Twelfth Doctor . ( TV : " Time Heist " ) Other mutant humans included Xais , as well as Eddie and Charlie Nisbett . ( AUDIO : " The Romance of Crime " )