Lobotomite Lobotomites are surgically - altered humans found at Big MT in the year 2281 . Background . Lobotomites are the result of medical experiments performed at Big MT . Most were residents or wanderers of the Mojave Wasteland unfortunate enough to have been collected by the Big MT drones before having all of their major organs replaced with electronic equivalents by the Sink ' s Auto - Doc routine . This routine was designed to keep all inhabitants of the Big MT inside and therefore secret , as only a brain inside a functioning human body can bypass the radar fence . The advanced Tesla coils that replaced the brains of the lobotomites were meant to allow individuals thus transformed to cognitively function with relative normalcy , operating their bodies remotely as the Courier does . However , a problem with the Auto - Doc ' s programming meant that every captive processed instead had their brains lobotomized or completely destroyed , rendering them mindlessly aggressive shells of what they once were . Generations of the Big MT ' s captives were maimed this way before the Courier ' s bullet - scarred brain forced the Auto - Doc to correct its own programming . Lobotomites are only capable of simple tasks such as using doors , walking , and fighting hand - to - hand or with firearms . They seem to have a proclivity for collecting random objects , as evinced by their base , the Cuckoo ' s Nest . They are actively hostile . Although they wear almost no armor , the modifications made to their bodies make them significantly tougher and more resistant to damage than the average human . Unable to talk normally , they mainly grunt but some can at times be heard saying " die , " " stop you , " and " never . " It also appears that the Tesla coils give them a relatively long life , since a lobotomite called Test Subject 1 , probably the first created in Big MT , is still alive in 2281 . Dr . Dala calls them " skinvelopes . " Her observations report that 43 % of the time when two lobotomites are left together , they will either fight for dominance or " . . . inject bodily fluids into each others ' orifices . " The Think Tank makes use of lobotomites for their various experiments - they can be found inside many labs , and the Courier can splice them with dogs and robots in the X - 8 research center - however , the Courier has very little to no control over the results of their splicing . Typically , lobotomites wear a torn patient hood with a respirator , headphones , and a pair of high - tech goggles , with straps to attach them all . They can be found all across Big MT , mostly around buildings and areas marked on the map . Characteristics . Lobotomites wear lobotomite jumpsuit s or patient gown s which offer very little protection against damage . This apparel has a low Damage Threshold , but the medium to high health of the lobotomites somewhat counterbalances this . Lobotomites are armed with either a firearm or melee weapon . They carry more powerful weapons at higher player levels , and can pose a credible threat even to very high level players , since at very high levels they often carry hunting revolver s or brush gun s . At all levels , melee - oriented lobotomites frequently carry Saturnite fist s or proton axe s . Usually , they attack in groups of three - with two melee - oriented members and one ranged . A single night stalker occasionally can be found in their group . Appearances . Lobotomites appear in the " " , " Old World Blues " . They also appeared on a loading screen of " Fallout " and they were to appear in " Fallout 2 " in a cut encounter . Bugs . Lobotomites are notorious for spawning right in front of the player . For example , fast - traveling to Ulysses ' Point and waiting for a few seconds will cause lobotomites to spawn near Higgs Village and in front of the entrance to Ulysses ' Point as well . The lobotomite that spawns at the entrance to Ulysses ' Point may actually exit from the entrance at times , but generally just pops up upon fast travel .