α-granules (containing platelet factor 4 , transforming growth factor-β1 , platelet-derived growth factor , fibronectin , B-thromboglobulin , vWF , fibrinogen , and coagulation factors V and XIII ). Thromboxane A2 synthesis Platelet activation initiates the arachidonic acid pathway to produce TXA2 . TXA2 is involved in activating other platelets and