higher incidence of opioid-related deaths in rural areas than urban areas. Epidemiology Opioids that are most commonly abused are oxycodone (79%), hydrocodone (67%), methadone (40%), morphine (29%), heroin (13%), hydromorphone (16%), fentanyl (9%) and buprenorphine (1%). Regular opium is also abused but is in some form listed previously. Etiology There are