pattern in a similar fashion. In the cytoplasm , spermidine and resveratrol induce convergent protein de-acetylation more frequently than convergent acetylation , while in the nucleus , acetylation is dominantly triggered by both agents. We surmise that subtle and concerted alterations in the acetylproteome regulate autophagy at multiple levels." Link: http://www.ncbi.nlm.nih.gov/pubmed/21460620