Best Female: Christina Aguilera Best Group: Depeche Mode Best Pop: Justin Timberlake Best Rock: The Killers Best R&B: Rihanna Best Hip-Hop: Kanye West Best Alternative: Muse Best Song: Gnarls Barkley , " Crazy " Best Video: Justice vs. Simian , "We Are Your Friends" Best Album: Red Hot Chili Peppers ,