by French chemist  Charles Frederic Gerhardt  in 1853), a modification of  salicylic acid  or  salicin , a  folk remedy  found in the  bark  of the  willow plant. By 1899, Bayer's  trademark   Aspirin  was registered worldwide for Bayer's brand of acetylsalicylic acid, but because of the confiscation of Bayer's US assets