on the island there are fifteen cities and towns which have a population above 50.000 people, these are: [ 74 ] Comune Population (May 2011) Palermo 655,343 Catania 292,855 Messina 242,121 Siracusa 123,248 Marsala 82,812 Gela 77,295 Ragusa 73,756 Trapani 70,642 Vittoria 63,393 Caltanissetta 60,221 Agrigento 59,190 Bagheria 56,421 Modica 55,294