Liposarcomas account for 15% of adult soft tissue sarcoma (STS); this is a heterogeneous group of tumors that are subdivided into five subgroups based on morphology and cytogenic abnormalities (Refs. 1, 2). Well-differentiated liposarcoma (WD) also known as atypical lipomatous tumor (ALT) and de-differentiated liposarcoma (DD) comprise the vast majority of