intoxications ( dinitrophenol , triethyltin , hexachlorophene , isoniazid ), in Reye's syndrome , severe hypothermia , early ischemia , encephalopathy , early stroke or hypoxia , cardiac arrest, pseudotumor cerebri, and cerebral toxins.   Osmotic cerebral edema Normally cerebral-spinal fluid (CSF) and extracellular fluid (ECF) osmolality of the brain is