our Maps page for general directions: www.posadacondominiums.com/Maps.htm From Phoenix: take I-10 east to Tucson. From Tucson: Take I-10 to I-19 south to Nogales , Arizona. San Carlos is about 270 miles/435 kilometers due south of Nogales, Arizona. Take I-19 south about 60 miles to Nogales, through Green Valley, Tubac, and Rio Rico.