reports of mucosal pigmentation associated with minocycline use. Hypersensitivity side effects have included anaphylactoid reactions, anaphylactoid purpura, anaphylaxis (including shock and fatalities), angioneurotic edema , autoimmune vasculitis , drug fever , eosinophilic pneumonitis , erythema multiforme , fixed drug eruptions , hepatitis , lupus-like syndrome , myocarditis , pericarditis , polyarthralgia