at regular intervals thereafter. Dose reduction or discontinuation of the SNRI should be considered in patients who experience a sustained increase in blood pressure or pulse rate. REFERENCE + Salmeterol and Cymbalta Product Information. Effexor (venlafaxine). Anonymous Wyeth-Ayerst Laboratories, Philadelphia, PA. PROD; Product Information. Savella (milnacipran). Anonymous Forest Pharmaceuticals, St. Louis,