In addition to its connection with AS, HLA-B27 is implicated in Reiter's syndrome , certain eye disorders such as acute anterior uveitis and iritis , psoriatic arthritis and ulcerative colitis . Reiter's syndrome then again, is statistically associated with AS. From: http://emedicine.medscape.com/article/1201027-overview   Clinical Features of HLA-B27 Syndromes - Reactive Arthritis Reactive