Deuterochloroform Main article: Deuterated chloroform Deuterated chloroform is an isotopologue of chloroform with a single deuterium atom. CDCl 3 is a common solvent used in NMR Spectroscopy . Deuterochloroform is produced by the haloform reaction [ citation needed ] , the reaction of acetone (or ethanol) with sodium hypochlorite or calcium hypochlorite.