108 ] Ibuprofen ( Advil )* can cause gastrointestinal irritation, stomach ulcers, and kidney damage in dogs. [ 109 ] Naproxen (Aleve)* has a long half-life in dogs and can cause gastrointestinal irritation, anemia, melena (digested blood in feces), and vomiting. [ 109 ] Antifreeze * is very dangerous to dogs