vasculitis . Thiazides may induce phototoxic dermatitis . In addition, a rare, distinct entity with clinical and laboratory features indistinguishable from those of subacute cutaneous lupus erythematosus is associated with HCTZ. A 67-year-old woman with hypothyroidism, hypercalcemia, depression, and hypertension developed facial erythema , headaches , tremors , confusion and personality changes