Deroxat, Pondera, Cebrilin, Aropax ) [back] Antidepressant s Paroxetine or paroxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI) antidepressant . Prozac was invented at Eli Lilly . It was released in 1992 by the pharmaceutical company GlaxoSmithKline and has since become one of the most prescribed antidepressants on the market, used