dysplasia Progressive retinal atrophy Epilepsy Entropion Hypothyroidism Hyperosteodystrophy Bloat Osteosarcoma Von Willebrand's disease Patent ductus ateriosus History The breed Irish Red Setter was developed in Ireland in the 1700s from the Old Spanish Pointer , setting spaniels , and early Scottish setters . Early Irish Setters were white with red blotches