or exacerbation of autoimmune diseases including idiopathic thrombocytopenic purpura , vasculitis , Raynaud's phenomenon , rheumatoid arthritis arthritis, psoriasis , interstitial nephritis , thyroiditis , lupus erythematosus , hepatitis , myositis and rhabdomyolysis have been reported in patients treated with alpha interferons. Any patient developing an autoimmune disorder during therapy should be