2'-epimerase , and uridine diphosphate-N-acetylglucosamine-2'-epimerase . This enzyme participates in aminosugars metabolism . In microorganisms this epimerase is involved in in the synthesis of the capsule precursor UDP-ManNAcA. [ 1 ] [ 2 ] Some of these enzymes are bifunctional. The UDP-N-acetylglucosamine 2-epimerase from rat liver displays both epimerase and kinase