, arthritis , aggravated arthritis , gouty arthritis , neck pain , cervical vertebral fracture, chondrocalcinosis pyrophosphate, steroid myopathy, myopathy , and spinal compression fracture have been reported. General side effects including fatigue (31.1%), pyrexia (20.9%), peripheral edema (20.3%), asthenia (14.9%), edema (10.1%), pain (6.8%), rigors (6.1%), chest pain (5.4%),