symptoms generally disappear during long-term treatment. Other reactions that have been reported with isosorbide mononitrate modified release tablets include   tachycardia , vomiting, diarrhoea,   vertigo   and heartburn. Interactions §                      Sildenafil   (Viagra). Concomitant administration of isosorbide mononitrate and sildenafil (Viagra) can potentiate the vasodilatory effect of isosorbide mononitrate