dogs, particularly  Westies  and  Cairn Terriers . [7] [8] Causes: Krabbe disease is caused by  mutations  in the  GALC   gene  located on  chromosome   14  (14q31), [9]  which causes a deficiency of an  enzyme  called  galactocerebrosidase . The build-up of unmetabolized lipids affects the growth of the nerve's protective myelin