claim: The Invisible Man came out after enforcement of the Motion Picture Production Code censorship guidelines took effect.
evidence: Noncovalent solid-phase organic synthesis or NC-SPOS is a form of Solid-phase synthesis whereby the organic substrate is bonded to the solid phase not by a covalent bond but by other chemical interactions .. Solid-phase synthesis. Solid-phase synthesis. covalent bond. covalent bond. This bond may consist of an induced dipole interaction between a hydrophobic matrix and a hydrophobic anchor .. induced dipole interaction. induced dipole interaction. hydrophobic. hydrophobic. As long as the reaction medium is hydrophilic -LRB- polar -RRB- in nature the anchor will remain on the solid phase .. Switching to a nonpolar solvent releases the organic substrate containing the anchor .. nonpolar solvent. nonpolar solvent. In one experimental setup the hydrophobic matrix is RP silica gel -LRB- C18 -RRB- and the anchor is acridone .. hydrophobic. hydrophobic. RP silica gel. RP silica gel. acridone. acridone. Acridone is N-alkylated and the terminal alkene group is converted into an aldehyde by ozonolysis .. Acridone. Acridone. alkene. alkene. aldehyde. aldehyde. ozonolysis. ozonolysis. This compound is bonded to RP silica gel and this system is subjected to a tandem sequence of organic reactions .. RP silica gel. RP silica gel. The first reaction is a Barbier reaction with propargylic bromide in water -LRB- green chemistry -RRB- and the second reaction is a Sonogashira coupling .. Barbier reaction. Barbier reaction. green chemistry. green chemistry. Sonogashira coupling. Sonogashira coupling. Substrates may vary in these sequences and in this way a chemical library of new compounds can be realized .. chemical library. chemical library. The phosphorus ligand in the Sonogashira coupling with phenyliodine is the water-soluble TPPTS ligand. Sonogashira coupling. Sonogashira coupling. TPPTS ligand. TPPTS ligand