claim: Adam Lambert was the first openly gay artist to top the U.S. Billboard 200.
evidence: Myostatin-related muscle hypertrophy -LRB- or myotonic hypertrophy -RRB- is a rare genetic condition characterized by reduced body fat and increased skeletal muscle size .. genetic condition. genetic condition. body fat. body fat. skeletal muscle. skeletal muscle. Affected individuals have up to twice the usual amount of muscle mass in their bodies .. They also tend to have increased muscle strength .. strength. Physical strength. Myostatin-related muscle hypertrophy is not known to cause many medical problems , and affected individuals are intellectually normal .. The prevalence of this condition is unknown .. Mutations in the MSTN gene cause myostatin-related muscle hypertrophy .. gene. gene. myostatin. myostatin. The MSTN gene provides instructions for making a protein called myostatin , which is active in muscles used for movement -LRB- skeletal muscles -RRB- both before and after birth .. gene. gene. protein. protein. myostatin. myostatin. skeletal muscles. skeletal muscles. birth. birth. This protein normally restrains muscle growth , ensuring that muscles do not grow too large .. protein. protein. Mutations that reduce the production of functional myostatin lead to an overgrowth of muscle tissue .. myostatin. myostatin. Myostatin-related muscle hypertrophy has a pattern of inheritance known as incomplete autosomal dominance .. People with a mutation in both copies of the MSTN gene in each cell -LRB- homozygotes -RRB- have significantly increased muscle mass and strength .. strength. Physical strength. gene. gene. cell. Cell ( biology ). People with a mutation in one copy of the MSTN gene in each cell -LRB- heterozygotes -RRB- also have increased muscle bulk , but to a lesser degree .. gene. gene. cell. Cell ( biology ). Researchers at Guangzhou Institutes of Biomedicine and Health in China have edited the genome of beagles to create double the amount of muscle .. China. China