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evidence: Game theory is `` the study of mathematical models of conflict and cooperation between intelligent rational decision-makers . ''. Game theory is mainly used in economics , political science , and psychology , as well as logic , computer science and biology .. economics. economics. political science. political science. psychology. psychology. logic. logic. computer science. computer science. biology. biology. Originally , it addressed zero-sum games , in which one person 's gains result in losses for the other participants .. Today , game theory applies to a wide range of behavioral relations , and is now an umbrella term for the science of logical decision making in humans , animals , and computers .. umbrella term. umbrella term. Modern game theory began with the idea regarding the existence of mixed-strategy equilibria in two-person zero-sum games and its proof by John von Neumann .. John von Neumann. John von Neumann. Von Neumann 's original proof used the Brouwer fixed-point theorem on continuous mappings into compact convex sets , which became a standard method in game theory and mathematical economics .. economics. economics. Brouwer fixed-point theorem. Brouwer fixed-point theorem. mathematical economics. mathematical economics. His paper was followed by the 1944 book Theory of Games and Economic Behavior , co-written with Oskar Morgenstern , which considered cooperative games of several players .. Theory of Games and Economic Behavior. Theory of Games and Economic Behavior. Oskar Morgenstern. Oskar Morgenstern. The second edition of this book provided an axiomatic theory of expected utility , which allowed mathematical statisticians and economists to treat decision-making under uncertainty .. This theory was developed extensively in the 1950s by many scholars .. Game theory was later explicitly applied to biology in the 1970s , although similar developments go back at least as far as the 1930s .. biology. biology. Game theory has been widely recognized as an important tool in many fields .. With the Nobel Memorial Prize in Economic Sciences going to game theorist Jean Tirole in 2014 , eleven game-theorists have now won the economics Nobel Prize .. economics. economics. Nobel Memorial Prize in Economic Sciences. Nobel Memorial Prize in Economic Sciences. Jean Tirole. Jean Tirole. John Maynard Smith was awarded the Crafoord Prize for his application of game theory to biology .. biology. biology. John Maynard Smith. John Maynard Smith. Crafoord Prize. Crafoord Prize