claim: Mamata Banerjee was banned from any political office positions in India in 2001.
evidence: Haptoglobin -LRB- abbreviated as Hp -RRB- is the protein that in humans is encoded by the HP gene .. protein. protein. gene. gene. In blood plasma , haptoglobin binds free hemoglobin -LRB- Hb -RRB- released from erythrocytes with high affinity and thereby inhibits its oxidative activity .. blood plasma. blood plasma. hemoglobin. hemoglobin. erythrocytes. erythrocytes. affinity. Affinity ( pharmacology ). oxidative. oxidative. The haptoglobin-hemoglobin complex will then be removed by the reticuloendothelial system -LRB- mostly the spleen -RRB- .. hemoglobin. hemoglobin. complex. protein complex. reticuloendothelial system. reticuloendothelial system. spleen. spleen. In clinical settings , the haptoglobulin assay is used to screen for and monitor intravascular hemolytic anemia .. hemolytic anemia. hemolytic anemia. In intravascular hemolysis , free hemoglobin will be released into circulation and hence haptoglobin will bind the hemoglobin .. hemoglobin. hemoglobin. This causes a decline in haptoglobin levels .. Conversely , in extravascular hemolysis the reticuloendothelial system , especially splenic monocytes , phagocytose the erythrocytes and hemoglobin is relatively not released into circulation ; however , excess hemolysis can release some hemoglobin causing haptoglobin levels to be decreased .. hemoglobin. hemoglobin. erythrocytes. erythrocytes. reticuloendothelial system. reticuloendothelial system. extravascular hemolysis. extravascular hemolysis. Therefore , haptoglobin is not a reliable way to differentiate between intravascular and extravascular hemolysis .. extravascular hemolysis. extravascular hemolysis