claim: Georges Gilles de la Tourette described symptoms in 1984.
evidence: Multiple EGF-like-domains 10 is a protein that in humans is encoded by the MEGF10 gene .. protein. protein. gene. gene. MEGF10 is a regulator of satellite cell myogenesis and interacts with Notch1 in myoblasts .. satellite cell. satellite cell. myogenesis. myogenesis. Notch1. Notch 1. It has been shown to be the cause of early-onset myopathy , areflexia , respiratory distress and dysphagia .. myopathy. myopathy. areflexia. areflexia. respiratory distress. respiratory distress. dysphagia. dysphagia. MEGF10 and MEGF11 , have critical roles in the formation of mosaics by two retinal interneuron subtypes , starburst amacrine cells and horizontal cells in mice .. MEGF11. MEGF11. amacrine cells. Retina amacrine cell. horizontal cells. Retina horizontal cell. These cells are less likely to be near neighbours of the same subtype than would occur by chance , resulting in ` exclusion zones ' that separate them .. Mosaic arrangements provide a mechanism to distribute each cell type evenly across the retina , ensuring that all parts of the visual field have access to a full set of processing elements .