claim: Heaven Can Wait came out before Here Comes Mr. Jordan.
evidence: Murine caspase-11 , and its human homologs caspase-4 and caspase-5 , are mammalian intracellular receptor proteases activated by TLR4 and TLR3 signaling during the innate immune response .. caspase-4. caspase-4. caspase-5. caspase-5. proteases. proteases. TLR4. TLR4. TLR3. TLR3. innate immune response. innate immune system. caspase. caspase. Caspase-11 , also termed the non-canonical inflammasome , is activated by TLR3 / TLR4-TRIF signaling and directly binds cytosolic lipopolysaccharide -LRB- LPS -RRB- , a major structural element of Gram-negative bacterial cell walls .. TLR4. TLR4. TLR3. TLR3. inflammasome. inflammasome. TRIF. TRIF. cytosolic. cytosolic. lipopolysaccharide. lipopolysaccharide. LPS. lipopolysaccharide. Activation of caspase-11 by LPS is known to cause the activation of other caspase proteins , leading to septic shock , pyroptosis , and often organismal death .. LPS. lipopolysaccharide. caspase. caspase. septic shock. septic shock. pyroptosis. pyroptosis