claim: The Siege of Fort Stanwix began on August 2, 1777.
evidence: It has been shown that integral membrane proteins that mediate the uptake of a wide variety of molecules with the concomitant uptake of sodium ions -LRB- sodium symporters -RRB- can be grouped , on the basis of sequence and functional similarities into a number of distinct families .. sodium. sodium. sequence. sequence ( biology ). One of these families is known as the sodium  : dicarboxylate symporter family -LRB- SDF -RRB- .. sodium. sodium. Such re-uptake of neurotransmitters from the synapses , is thought to be an important mechanism for terminating their action , by removing these chemicals from the synaptic cleft , and transporting them into presynaptic nerve terminals , and surrounding neuroglia .. mechanism. Nuclear receptor#Mechanism of action. chemicals. chemical substance. synaptic. Synapse. presynaptic. presynaptic. nerve. nerve. this removal is also believed to prevent them accumulating to the point of reaching neurotoxic .. neurotoxic. Neurotoxicity. The structure of these transporter proteins has been variously reported to contain from 8 to 10 transmembrane -LRB- TM -RRB- regions , although 10 now seems to be the accepted value .. structure. secondary structure. transporter. membrane transporter protein. transmembrane. Protein kinase#Receptor tyrosine kinases. Members of the family include  : several mammalian excitatory amino acid transporters , and a number of bacterial transporters .. amino acid. amino acid. transporters. membrane transport protein. They vary with regars to their dependence on transport of sodium , and other ions .. sodium. sodium