claim: Proponents of globalism tend to advocate for lowering budgets.
evidence: The S9 fraction is the product of an organ tissue homogenate used in biological assays .. homogenate. homogenization ( biology ). The S9 fraction is most frequently used in assays that measure the metabolism of drugs and other xenobiotics .. metabolism. metabolism. It is defined by the U.S. National Library of Medicine 's `` IUPAC Glossary of Terms Used in Toxicology '' as the `` Supernatant fraction obtained from an organ -LRB- usually liver -RRB- homogenate by centrifuging at 9000 g for 20 minutes in a suitable medium ; this fraction contains cytosol and microsomes . ''. homogenate. homogenization ( biology ). U.S. National Library of Medicine. U.S. National Library of Medicine. IUPAC. IUPAC. Supernatant. Supernatant. centrifuging. centrifuge. cytosol. cytosol. microsomes. microsomes. The microsomes component of the S9 fraction contain cytochrome P450 isoforms -LRB- phase I metabolism -RRB- and other enzyme activities .. metabolism. metabolism. microsomes. microsomes. cytochrome P450. cytochrome P450. phase I metabolism. Drug metabolism#Phase I. The cytosolic portion contains the major part of the activities of transferases -LRB- phase II metabolism -RRB- .. metabolism. metabolism. phase II metabolism. Drug metabolism#Phase II. The S9 fraction is easier to prepare than purified microsomes .. microsomes. microsomes