Humulin L, LENTE
date: label: date made
content: before March 1995
name: label: maker
content: Eli Lilly and Company
notes: label: Description (Brief)
content: Humulin is human insulin used for treating diabetes. Prior to its development, diabetics used insulin isolated from pig and cow pancreases. Developed by Genentech, the first American biotechnology company, Humulin was licensed to Eli Lilly and became the first marketable product created through recombinant DNA technology. Its licensing by the FDA in October 1982 also made it the first recombinant pharmaceutical approved for use in the United States.
label: Description (Brief)
content: Recombinant pharmaceuticals are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for human insulin are inserted into bacteria. Bacteria produce insulin, which is harvested and used as the active ingredient in Humulin.
label: Description (Brief)
content: Humulin L is an intermediate-acting insulin with a slower onset of action than regular insulin and a longer duration of activity (up to 24 hours). Due to declining use of longer-acting insulins, Humulin L was discontinued in 2005.
label: Description (Brief)
content: Object is a sealed white cardboard box with black and red printing.
label: Location
content: Currently not on view
place: label: place made
content: United States: Indiana, Indianapolis
setName: label: See more items in
content: Medicine and Science: Medicine
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content: Health & Medicine
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content: Biotechnology and Genetics
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content: Recombinant Pharmaceuticals
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content: Science & Mathematics
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content: Diabetes
dataSource: label: Data Source
content: National Museum of American History
identifier: label: ID Number
content: 2012.0046.46
label: accession number
content: 2012.0046
label: catalog number
content: 2012.0046.46
objectType: label: Object Name
content: pharmaceutical
label: Object Name
content: biological
label: Object Name
content: insulin
physicalDescription: label: Physical Description
content: human insulin (overall material)
label: Measurements
content: overall: 2 3/4 in x 1 3/8 in x 1 3/8 in; 6.985 cm x 3.4925 cm x 3.4925 cm
label: Measurements
content: overall: 1 5/16 in x 2 7/8 in x 1 5/16 in; 3.33375 cm x 7.3025 cm x 3.33375 cm