Actimmune, Interferon gamma-1b injection
date: label: date made
content: before November 1993
name: label: maker
content: Genentech, Inc.
notes: label: Description (Brief)
content: Actimmune is a recombinant pharmaceutical used to treat children and adults with chronic granulomatous disease (CGD, an immune system disorder) and severe, malignant osteopetrosis (a disease which causes bones to become extremely dense and can lead to blindness, scoliosis, and a number of other problems).
label: Description (Brief)
content: Recombinant pharmaceuticals are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for human interferon are inserted into bacteria. Interferon is a substance that is naturally made by the body to fight infections and tumors. Bacteria produce the interferon, which is harvested and used as the active ingredient in Actimmune.
label: Description (Brief)
content: Object is a plastic clamshell-style box with tabs for opening labeled "HOLD" and "LIFT." Box contains 12 single-dose vials, which are round, clear glass bottles with blue plastic tops and white labels with black and green printing.
label: Location
content: Currently not on view
place: label: place made
content: United States: California, South San Francisco
setName: label: See more items in
content: Medicine and Science: Medicine
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content: Health & Medicine
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content: The Antibody Initiative
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content: Biotechnology and Genetics
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content: Recombinant Pharmaceuticals
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content: Science & Mathematics
label: See more items in
content: Antibody Initiative: Monoclonal Antibodies
dataSource: label: Data Source
content: National Museum of American History
identifier: label: ID Number
content: 2012.0046.49
label: accession number
content: 2012.0046
label: catalog number
content: 2012.0046.49
objectType: label: Object Name
content: biological
label: Object Name
content: pharmaceutical, recombinant
physicalDescription: label: Measurements
content: overall: 1 3/4 in x 4 1/8 in x 3 5/8 in; 4.445 cm x 10.4775 cm x 9.2075 cm
label: Measurements
content: overall: 1 3/4 in x 4 1/8 in x 3 3/4 in; 4.445 cm x 10.4775 cm x 9.525 cm