Posilac, sterile sometribove zinc suspension
date: label: date made
content: April 1993 to June 1994
label: product expiration date
content: 1994-06
name: label: maker
content: Monsanto Company
notes: label: Description (Brief)
content: Posilac is a recombinant pharmaceutical used to increase milk production in lactating dairy cows. Approved by the FDA in 1993, Posilac was the first biotechnology product offered for sale by Monsanto. The company sold the rights to Elanco, a division of Eli Lilly and Company in 2008.
label: Description (Brief)
content: Its active ingredient, bovine growth hormone-also known as rBGH and rBST-has been at the center of ongoing controversy in the United States. Although deemed safe by the FDA, rBGH is banned in many other countries. American consumer groups have countered FDA claims of safety with concerns about possible health risks stemming from differences in milk produced by cows treated with rBGH and milk produced by untreated cows.
label: Description (Brief)
content: Recombinant pharmaceuticals like Posilac are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for bovine somatotropin (growth hormone) are inserted into bacteria. Bacteria produce the somatotropin, which is harvested and used as the active ingredient in Posilac.
label: Description (Brief)
content: Object consists of a white cardboard box with light blue, dark blue, and red printing. Box contains 25 needles, 25 syringes, and a product insert. Needles are disposable, wrapped individually, and have a purple plastic base and a clear plastic cap. Syringes are 500-mg single doses, and they are made of white plastic with white labels with red, blue, and black printing.
label: Location
content: Currently not on view
place: label: place made
content: United States: Missouri, Saint Louis
label: place made
content: Austria
label: place made
content: Netherlands
setName: label: See more items in
content: Medicine and Science: Medicine
label: See more items in
content: Health & Medicine
label: See more items in
content: Biotechnology and Genetics
label: See more items in
content: Recombinant Pharmaceuticals
label: See more items in
content: Science & Mathematics
dataSource: label: Data Source
content: National Museum of American History
identifier: label: ID Number
content: 2012.0046.50
label: accession number
content: 2012.0046
label: catalog number
content: 2012.0046.50
objectType: label: Object Name
content: pharmaceutical
physicalDescription: label: Physical Description
content: sometribove zinc, 500 mg (drug active ingredients)
label: Measurements
content: overall: 2 1/4 in x 4 3/4 in x 6 1/2 in; 5.715 cm x 12.065 cm x 16.51 cm