Recombivax HB, Hepatitis B Vaccine (Recombinant) Pediatric Formulation, 0.5 mL
date: label: date made
content: ca 1988
label: product expiration date
content: 1988-05-14
name: label: maker
content: Merck Sharp and Dohme
notes: label: Description (Brief)
content: Recombivax HB is a vaccine that provides immunization against hepatitis B. It is injected intramuscularly. Recombivax HB is the first recombinant vaccine. Prior hepatitis B vaccines relied on viruses derived from human blood sources.
label: Description (Brief)
content: Recombinant pharmaceuticals are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for the hepatitis B virus's surface antigen are inserted into yeast. Yeast produce the hepatitis B surface antigens, which are harvested and used as the active ingredient in Recombivax HB. Surface antigens are the part of the hepatitis B virus that the body recognizes to create an immune response. After being exposed to the antigen, the body learns to identify and respond quickly to the presence of hepatitis B and can successfully ward off future possible infections.
label: Description (Brief)
content: Object consists of a white cardboard box with light blue stripes and light blue, red, and black printing. Box contains a product insert and a round clear glass bottle with metal top and white label. Bottle contains clear solution.
label: Location
content: Currently not on view
place: label: place made
content: United States: Pennsylvania, West Point
topic: label: Subject
content: Vaccines
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content: Medicine and Science: Medicine
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content: Health & Medicine
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content: The Antibody Initiative
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content: Biotechnology and Genetics
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content: Antibody Initiative: Infectious Disease, Allergy, and Immunotherapy Collections
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content: Recombinant Pharmaceuticals
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content: Science & Mathematics
dataSource: label: Data Source
content: National Museum of American History
identifier: label: ID Number
content: 1987.0782.01
label: accession number
content: 1987.0782
label: catalog number
content: 1987.0782.01
objectType: label: Object Name
content: biological
label: Object Name
content: vaccine, hepatitis
physicalDescription: label: Physical Description
content: Hepatitis B surface antigen on alum adjuvant, 5 mcg (drug active ingredients)
label: Measurements
content: overall: 2 1/2 in x 1 5/16 in x 1 3/16 in; 6.35 cm x 3.33375 cm x 3.01625 cm
label: Measurements
content: bottle: 3.3 mm x 1.4 cm; 1/8 in x 9/16 in