Intocostrin, 5cc, 100 Units, (A Physiologically Standardized preparation from Curare)
date: label: date made
content: before 1951-04-24
label: product expiration date
content: 1951-04-24
name: label: maker
content: Bristol-Myers Squibb Company
notes: label: Description
content: The indications or use of this product as provided by the manufacturer are: Clinical investigation indicates Intocostrin can be used to supplement anesthetic agents, inducing a muscular relaxation which facilitates surgery. When given intravenously immediately before the shock therapy of mental disease, it is useful in softening the severity of convulsions and preventing fractures. It produces a more or less transient but often useful relaxing effect in certain neurologic conditions. It may be useful for its relaxing effect in carrying out certain manipulative diagnostic procedures as well as in the reduction of fractures or dislocations. The specific action of curare is useful in the diagnosis of myasthenia gravis. [from paper insert]
label: Description
content: Yellow paper-covered cardboard box with yellow and brown label. Box contains one glass vial with rubber and metal stopper and paper label, and one paper insert. Vial is about 60% full of brownish liquid. List 4854; Lot No. 0090320.
label: Description
content: In 1939 E. R Squibb & Sons introduced Intocostrine, the first commercially available preparation of curare for clinical use. The drug is an extract of the South American vine Chondrodendron tomentosum, one of the principal sources of curare. The active alkaloid, d-tubocurarine chloride, was isolated in crystalline form in the mid-1930s.
label: Location
content: Currently not on view
place: label: place made
content: United States: New York, New York City
setName: label: See more items in
content: Medicine and Science: Medicine
dataSource: label: Data Source
content: National Museum of American History
identifier: label: ID Number
content: 1980.0076.056
label: accession number
content: 1980.0076
label: catalog number
content: 1980.0076.056
label: serial number
content: 0C90320
objectType: label: Object Name
content: pharmaceutical
physicalDescription: label: Physical Description
content: chondodendron tomentosum extract, purified (drug active ingredients)
label: Measurements
content: overall: 1 1/8 in x 2 5/8 in x 1 in; 2.8575 cm x 6.6675 cm x 2.54 cm