Orthotopic Homotransplantation of the Mammalian Heart
name: label: Collection Creator
content: National Museum of American History (U.S.). Division of Medical Sciences
label: Collection Creator
content: National Museum of American History (U.S.). Division of Medical Sciences
setName: label: See more items in
content: Medical Sciences Film Collection
label: See more items in
content: Medical Sciences Film Collection / Series 1: Technical Films
physdesc: label: Extent
content: 1 Film reel (color, composite optical soundtrack, print, 16mm; 390 feet)
unitdate: label: Date
content: 1968
container: label: Container
content: Reel OF 222.17
dataSource: label: Archival Repository
content: Archives Center, National Museum of American History
objectType: label: Type
content: Archival materials
label: Type
content: Film reels
scopecontent: label: Scope and Contents
content: Title and date on can label: Orthotopic Homotransplantation of the Heart in Puppies, 1964. 

Credits: cinematographer: Harold Friedman, BPA from the Clinical Congress of the American College of Surgeons; Yoshio Kondo, M.D., Franz Gradel, M.D., Adrian Kantrowitz, M.D. from the Division of Surgical Research, Maimonides Hospital of Brooklyn; supported by U.S.P.H.S. Grant # H-6510.

Summary: an attempt to develop a practical technique for transplantation of the heart in puppies under profound hypothermia, thus avoiding the use of a pump oxygenerator. Recipient is cooled to about 16 degrees C.; donor is cooled to 28 degrees C. The recipient's chest is opened and the slow-beating heart under this degree of hypothermia is removed. The donor's heart is removed by another surgical team and kept in a cold solution until needed.  It is attached to the recipient, taking care to make a water-tight seal and traumatize the tissue as little as possible. The aorta is re-attached and all air removed. The operation takes 45 minutes. We're shown the growth and development of three pups with transplanted hearts. No immunosuppresant drugs were used.