Now It's One—A Rationale of the One-Disc Concept
name: label: Collection Creator
content: National Museum of American History (U.S.). Division of Medical Sciences
label: Collection Creator
content: National Museum of American History (U.S.). Division of Medical Sciences
setName: label: See more items in
content: Medical Sciences Film Collection
label: See more items in
content: Medical Sciences Film Collection / Series 4: Pharmaceutical Films
physdesc: label: Extent
content: 1 Film reel (color, composite optical soundtrack, print, 16mm; 500 feet)
unitdate: label: Date
content: 1976
container: label: Container
content: Reel OF 222.78
dataSource: label: Archival Repository
content: Archives Center, National Museum of American History
objectType: label: Type
content: Archival materials
label: Type
content: Film reels
scopecontent: label: Scope and Contents
content: Credits: Live action by Palamar Productions, Inc.; graphics by Sunflower Films, Inc.; written by L. Elaine Busz, B.S. and Mitchell Kory, Ph.D.; Eli Lilly Co., consultants, L.D. Bechtol, Ph.D., M.D.; J.D. German, M.D.; David A. Preston, Waren Wick.

Summary: The film presents the rationale of the one-disc method for susceptibility testing of related antibiotics.  In this case the four Cephalsporin's (Cephalothin, cephaloridine, cephalexin, and cephaloglycin). There is a brief description of susceptibility testing methods. The basis for correlation of zone size with minimum inhibitory concentration (MIC), the significance of regression lines, the interpretation of zone sizes, and data on the clinical feasibility of the one-disc method are discussed and shown in live-action photography and animation. Clinical judgment of the physician is key to the recovery of the patient. This system provides rapid and accurate data to the physician to prescribe the appropriate therapy.