sentences: Biallelic and gene-wide genomic substitution for endogenous intron and retroelement mutagenesis in human cells


sentences: Fabrication of Conductive Hollow Microfibers for Encapsulation of Astrocyte Cells

labels: bioengineering


sentences: A deep unsupervised language model for protein design

labels: bioinformatics


sentences: CRISPRcleanR WebApp: an interactive web application for processing genome-wide pooled CRISPR-Cas9 viability screen


sentences: Ion channel model reduction using manifold boundaries

labels: biophysics


sentences: Prokaryotic genome design is ruled by the mechanical properties and complexity of the DNA sequence


sentences: Insight into Polyproline II Helical Bundle Stability and Folding from NMR Spectroscopic Characterization of the Snow Flea Antifreeze Protein Denatured State


sentences: Cardiac ventricular myosin and slow skeletal myosin exhibit dissimilar chemo-mechanical properties despite the same myosin heavy chain isoform.


sentences: Pan-cancer distribution of cleaved cell-surface Amphiregulin, the target of the GMF-1A3 antibody drug conjugate

labels: cancer biology


sentences: Flotillin-2 regulates EGFR activation, degradation, and cancer growth


sentences: Structure and function of diadenylate cyclase DacM from Mycoplasma ovipneumoniae

labels: pathology


sentences: Adipocyte-specific ablation of the Ca2+ pump SERCA2 impairs whole-body metabolic function and reveals the diverse metabolic flexibility of white and brown adipose tissue.

labels: physiology


sentences: Odors drive feeding through gustatory receptor neurons in Drosophila

labels: neuroscience


sentences: BLMM: Parallelised Computing for Big Linear Mixed Models


sentences: Cellular stress in brain organoids is limited to a distinct and bioinformatically removable subpopulation.


sentences: A Trem2*R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques


sentences: Organization of thalamocortical structural covariance and a corresponding 3D atlas of the mouse thalamus


sentences: Neuromodulation of striatal D1 cells shapes BOLD fluctuations in anatomically connected thalamic and cortical regions


sentences: Development of a PET radioligand for α2δ-1 subunit of calcium channels for imaging neuropathic pain


sentences: Electroencephalographic dynamics of rhythmicbreath-based meditation


sentences: Alpha-1-antitrypsin binds to the glucocorticoid receptor with biological significance in macrophages

labels: immunology


sentences: The role of Staphylococcus agnetis and Staphylococcus hyicus in the pathogenesis of buffalo fly skin lesions in cattle

labels: microbiology


sentences: Hypoxia shapes the immune landscape in lung injury promoting inflammation persistence

labels: cell biology


sentences: Automated classification of estrous stage in rodents using deep learning


sentences: ID1 and CEBPA Coordinate Epidermal Progenitor Cell Differentiation

labels: developmental biology


sentences: Estimating contemporary migration numbers of adults based on kinship relationships in iteroparous species

labels: ecology


sentences: Effects of disease emergence on invasive grass impacts


sentences: Analysis of synthetic genetic interactions of non-coding RNAs in Saccharomyces cerevisiae

labels: genetics


sentences: Oxytocin and Emotional Tear in Dogs

labels: animal behavior and cognition


sentences: Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development

labels: biochemistry


sentences: Double NPY motifs at the N-terminus of Sso2 synergistically bind Sec3 to promote membrane fusion


sentences: Generating minimum set of gRNA to cover multiple targets in multiple genomes with MINORg


sentences: Mechanical stress driven by rigidity sensing governs epithelial stability


sentences: Direct measurement of the aerotactic response in a bacterial suspension


sentences: Evaluating the "cost of generating force" hypothesis across frequency in human running and hopping


sentences: Robust high-throughput phenotyping with deep segmentation enabled by a web-based annotator

labels: plant biology


sentences: Characterization of dengue virus 3UTR RNA binding proteins in mosquitoes reveals that AeStaufen reduces subgenomic flaviviral RNA in saliva

labels: zoology


sentences: The role of UBE3A in the autism and epilepsy-related Dup15q syndrome using patient-derived, CRISPR-corrected neurons


sentences: Pan-phylum In Silico Analyses of Nematode Endocannabinoid Signalling Systems Highlight Novel Opportunities for Parasite Drug Target Discovery


sentences: Domain-general and domain-specific functional networks of Broca's area underlying language processing


sentences: The maternal X chromosome impairs cognition and accelerates brain aging through epigenetic modulation in female mice


sentences: Influenza A Virus Compromises anti-Streptococcal Innate Immunity


sentences: IFN-induced protein with tetratricopeptide repeats 2 (Ifit2) limits autoimmune inflammation by regulating myeloid cell activation and metabolic activity


sentences: Functional entry of Members of Venezuelan Equine Encephalitis Complex into host cells is dependent on clathrin-mediated endocytosis, in a pH-Dependent Manner


sentences: Optical photothermal infrared spectroscopy can differentiate equine osteoarthritic plasma extracellular vesicles from healthy controls

labels: molecular biology


sentences: Alveolar regeneration following viral infection is independent of tuft cells


sentences: An easily modifiable conjugative plasmid for studying horizontal gene transfer

labels: evolutionary biology


sentences: Using Local Genetic Correlation Improves Polygenic Score Prediction Across Traits

labels: genomics


sentences: Floating EMG Sensors and Stimulators Wirelessly Powered and Operated by Volume Conduction for Networked Neuroprosthetics

labels: bioengineering


sentences: Improved eukaryotic detection compatible with large-scale automated analysis of metagenomes

labels: bioinformatics


sentences: Accurate in silico confirmation of rare copy number variant calls from exome sequencing data using transfer learning


sentences: Web-based Histology Reference Atlas for the Freshwater Crustacean Daphnia magna


sentences: A connectomics-based taxonomy of mammals


sentences: Genetic mapping of APP and amyloid-β biology modulation by trisomy 21


sentences: In vitro susceptibility to beta-lactam antibiotics and viability of Neisseria gonorrhoeae strains producing plasmid-mediated broad- and extended-spectrum beta-lactamases


sentences: The role of Cycloastragenol at the intersection of Nrf-2/ARE, telomerase, and proteasome activity


sentences: Novel pathogen introduction rapidly alters evolved movement strategies, restructuring animal societies


sentences: Optimized high-throughput screening of non-coding variants identified from genome-wide association studies


sentences: Observation of a single protein by ultrafast X-ray diffraction

labels: biophysics


sentences: Calcium-induced environmental adaptability of the blood protein vitronectin


sentences: Field and experimental data together with computational models reveal how cleaner fish adjust decisions in a biological market


sentences: Reference genome choice and filtering thresholds jointly influence phylogenomic analyses


sentences: Blockade of redox second messengers inhibits JAK/STAT and MEK/ERK signaling sensitizing FLT3-mutant acute myeloid leukemia to targeted therapies

labels: cancer biology


sentences: Triosephosphate export from chloroplasts regulates flavonoid biosynthesis and permits high light acclimation through the inactivation of SnRK1


sentences: Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain

labels: neuroscience


sentences: Modelling the modulation of cortical Up-Down state switching by astrocytes


sentences: Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease


sentences: Placental inflammation leads to abnormal embryonic heart development

labels: immunology


sentences: Prokaryotic phospholipid translocation by ubiquitous PplT domain proteins

labels: microbiology


sentences: Cost-effectively dissecting the genetic architecture of complex wool traits in rabbits by low-coverage sequencing


sentences: Resolving clonal substructure from single cell genomic data using CopyKit


sentences: Structural and biochemical insights into lipid transport by VPS13 proteins.

labels: cell biology


sentences: Deep learning in human neurons predicts mechanistic subtypes of Parkinson's


sentences: The inositol-requiring enzyme 1α/X-box protein 1 (IRE1α/XBP1) pathway of the unfolded protein response is impaired in pediatric cholestatic liver disease explants


sentences: Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction


sentences: Oligomer-to-Monomer Transition Underlies the Chaperone Function of AAGAB in AP1/AP2 Assembly


sentences: State-of-the-Art Estimation of Protein Model Accuracy using AlphaFold


sentences: Cryo-EM structure of amyloid fibril formed by α-synuclein familial A53E mutation


sentences: Loss of tumor suppressor WWOX enhances RAS activity in pancreatic cancer


sentences: The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor


sentences: Visualization of mRNA Expression in Pseudomonas aeruginosa Aggregates Reveals Spatial Patterns of Fermentative and Denitrifying Metabolism


sentences: IRONMAN interacts with OsHRZ1 and OsHRZ2 to maintain Fe homeostasis


sentences: Accurate detection of structural variation is hard


sentences: Impact of dominance rank specification in dyadic interaction models


sentences: Interspecies isobaric labeling-based quantitative proteomics reveals protein changes in the ovary of Aedes aegypti co-infected with ZIKV and Wolbachia


sentences: Single-cell microfluidic analysis unravels individual cellular fates during Double-Strand Break Repair


sentences: Continuous extraction and concentration of secreted metabolites from engineered microbes using membrane technology


sentences: Combining two Genetic Sexing Strains allows sorting of non-transgenic males for Aedes genetic control


sentences: Uncertainty quantification in the cerebral circulation simulation focusing on the collateral flow: Surrogate model approach with machine learning


sentences: Towards unsupervised classification of macromolecular complexes in cryo electron tomography: challenges and opportunities


sentences: Predicting the structure of large protein complexes using AlphaFold and sequential assembly


sentences: Dynamics of endogenous PARP1 and PARP2 during DNA damage revealed by live-cell single-molecule imaging


sentences: Dissecting β-Cardiac Myosin and Cardiac Myosin-Binding Protein C Interactions using a Nanosurf Assay


sentences: Systemic circulating microRNA landscape in Lynch syndrome


sentences: Predicting systemic and pulmonary tissue barrier concentration of orally inhaled drug products

labels: pharmacology and toxicology


sentences: The pho1;2a'-m1.1 allele of Phosphate1 conditions mis-regulation of the phosphorus starvation response in maize (Zea mays ssp. mays L.)


sentences: Cold-induced cyt elevations function to support osmoregulation in marine diatoms


sentences: Pulvinar Slits: Cellulose-deficient and De-esterified Homogalacturonan-rich Structures in a Legume Motor Cell


sentences: Improving an rRNA depletion protocol with statistical design of experiments

labels: systems biology


sentences: Use of Avian Adeno-Associated Virus for the Delivery of Transgenes to Pekin Duck Cells in vitro and in vivo


sentences: New distribution data and phylogenetic approach reveal bioregionalization of the western Palearctic ants


sentences: Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates that reduce surface AMPA receptor expression in primary neurons


sentences: Species-specific chromatin landscape determines how transposable elements shape genome evolution


sentences: THE STABILIZATAION OF C-MYC BY THE NOVEL CELL CYCLE REGULATOR, SPY1, DECREASES EFFICACY OF BREAST CANCER TREATMENTS


sentences: ATR-I774Yfs*5 promotes genomic instability through micronuclei formation


sentences: Taxonomic investigation of the zooplanktivorous Lake Malawi cichlids Copadichromis mloto (Iles) and C. virginalis (Iles).


sentences: Comparing the potential of microglia preparations generated using different human iPSC-based differentiation methods to model microglia-mediated mechanisms of amyotrophic lateral sclerosis pathophysiology


sentences: Purinergic P2X7 Receptor-mediated inflammation precedes PTSD-related Behaviors in Rats


sentences: The pore-forming protein gasdermin D is a cellular redox sensor


sentences: Evolutionary Principles of Bacterial Signaling Capacity and Complexity


sentences: Identification of unusually disulphide-bonded insulin forms using mass spectrometry and thermolysin cleavage


sentences: Interstrand Crosslinks in Donor DNA Boost Gene Editing in Human Cells


sentences: Ecdysone signaling controls early embryogenesis in the short-germ hemimetabolous insect Blattella germanica.

labels: developmental biology


sentences: Robustness of field studies evaluating biodiversity responses to invasive species management in New Zealand

labels: ecology


sentences: Anatomical, ontogenetic, and genomic homologies guide reconstructions of the teeth-to-baleen transition in mysticete whales


sentences: Dynamic evolution of recently duplicated genes in Caenorhabditis elegans


sentences: Variation in cytonuclear expression accommodation among allopolyploid plants


sentences: Opiate responses are controlled by interactions of Oprm1 and Fgf12 loci in the murine BXD family: Correspondence to human GWAS finding

labels: genetics


sentences: Retained introns in long RNA-seq reads are not reliably detected in sample-matched short reads


sentences: Protein arginine and lysine methylation in Trypanosoma cruzi


sentences: Snaq: A Dynamic Snakemake Pipeline for Microbiome data analysis with QIIME2


sentences: Identifying transcription factor-DNA interactions using machine learning


sentences: EZH2 endorses cell plasticity to carcinoma cells facilitating mesenchymal to epithelial transition and tumour colonization


sentences: The GHB analogue HOCPCA improves sensorimotor function after MCAO via CaMKIIα


sentences: Transcutaneous electrical nerve stimulation modulates corticospinal excitability while preserving motor unit discharge properties during isometric contractions

labels: physiology


sentences: Candidatus Liberibacter asiaticus reduces callose and reactive oxygen species production in the phloem

labels: plant biology


sentences: Assessing cats' (Felis catus) sensitivity to human pointing gestures

labels: animal behavior and cognition


sentences: The rostral medial frontal cortex is crucial for engagement in consummatory behavior


sentences: The Speech Envelope Following REsponse in Normal and Hearing Impaired Listeners


sentences: Neural Activity in Afferent Projections to the Infralimbic Cortex is Associated with Individual Differences in the Recall of Fear Extinction.


sentences: The NIN-LIKE PROTEIN 7 (NLP7) transcription factor modulates auxin pathways to regulate root cap development


sentences: Integration of multi-omics data reveals interplay between brassinosteroid and TORC signaling in Arabidopsis


sentences: Co-release of histamine and GABA in prefrontal cortex excites fast-spiking interneurons and causes divisive gain change in pyramidal cells; an effect that is enhanced in older mice


sentences: Ultrastructure of COPII vesicle formation characterised by correlative light and electron microscopy.


sentences: Regulation of Cardiomyocyte Adhesion and Mechanosignalling Through Distinct Nanoscale Behaviour of Integrin Ligands Mimicking Healthy or Fibrotic ECM


sentences: PP2A forestalls mitophagy by dephosphorylating Parkin and ubiquitin

labels: biochemistry


sentences: Helical ultrastructure of the oncogenic metalloprotease meprin α in complex with a small molecule hydroxamate inhibitor


sentences: Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery


sentences: Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis


sentences: Microtubules control Buc Phase separation and Balbiani body condensation in zebrafish oocyte polarity


sentences: Chondroitin Sulfate Proteoglycan 4,6 sulfation regulates sympathetic nerve regeneration after myocardial infarction


sentences: Maternal diet and gut microbiota influence predisposition to cardiovascular disease in the offspring


sentences: How large and diverse are field populations of fungal plant pathogens? The case of Zymoseptoria tritici


sentences: Identification of the gene coding for seed cotyledon albumin SCA in the pea (Pisum L.) genome

labels: molecular biology


sentences: Predation increases prey fitness via transgenerational priming


sentences: A genomic analysis of parasite-mediated population differentiation in a metapopulation

labels: evolutionary biology


sentences: Comparison of CRISPR/Cas9-mediated megabase-scale genome deletion methods in mouse embryonic stem cells

labels: genomics


sentences: Environmental DNA sequencing data from algal blooms in Lake Erie using Oxford Nanopore MinION


sentences: Comprehensive phylogenomics of Methylobacterium reveals four evolutionary distinct groups and underappreciated phyllosphere diversity.


sentences: Protein Language Model Performs Efficient Homology Detection

labels: bioinformatics


sentences: An immune-lncRNA risk model to predict prognosis for patients with head and neck squamous cell carcinoma


sentences: ILnc: Prioritizing Long Non-coding RNAs for Pan-cancer Analysis of Immune Cell Infiltration


sentences: Systems level analysis of time and stimuli specific signaling through PKA


sentences: Reliability of M1-P15 as a cortical marker for transcallosal inhibition: a preregistered TMS-EEG study

labels: neuroscience


sentences: Evaluating spatial and network properties of NMDA-dependent neuronal connectivity in mixed cortical cultures


sentences: Modulation of glucose metabolism by 2-Deoxy-D-Glucose (2DG) promotes IL-17 producing human T cell subsets

labels: immunology


sentences: The cancer chemotherapeutic 5-fluorouracil is a potent inhibitor of Fusobacterium nucleatum and its activity is modified by the intratumoral microbiota

labels: microbiology


sentences: Direct colorimetry of imipenem decomposition as a novel cost effective method for detecting carabapenamase producing bacteria


sentences: High nutrient loads hinder successful restoration of natural habitats in freshwater wetlands


sentences: Diversity and determinants of recombination landscapes in flowering plants


sentences: Fast analyzing, exploring and sharing quantitative omics data using omicsViewer


sentences: RF4Del: A Random Forest approach for accurate deletion detection


sentences: Gene selection by incorporating genetic networks into case-control association studies


sentences: Photoacoustic imaging reveals mechanisms of rapid-acting insulin formulations dynamics at the injection site


sentences: A distinct subset of oligodendrocyte lineage cells interact with the developing dorsal root entry during its genesis


sentences: Dynamics of brain-fluid circulation are altered in the mature-onset Tet-off APP mouse model of amyloidosis


sentences: Cortical interneuron loss and seizure generation as novel clinically relevant disease phenotypes in Cln2R207X mice


sentences: Deletion of can1/cat1 genes and expression of a dominant any1 mutation establish an effective canavanine selection in fission yeast


sentences: Ecology and evolution of chlamydial symbionts of arthropods


sentences: Stack Mapping Anchor Points (SMAP): a versatile suite of tools for read-backed haplotyping


sentences: CATHe: Detection of remote homologues for CATH superfamilies using embeddings from protein language models


sentences: ViReMa: A Virus Recombination Mapper of Next-Generation Sequencing data characterizes diverse recombinant viral nucleic acids


sentences: STracking: a free and open-source python library for particle tracking and analysis


sentences: Hyperuricemia triggers Renal Tubular Epithelial Pyroptosis by using ROS to activate the NLRP3 inflammasome

labels: pathology


sentences: MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium


sentences: Beyond energy balance in agrivoltaic food production: Emergent crop traits from color selective solar cells


sentences: Systematic dissection of phosphorylation-dependent YAP1 complex formation elucidates a key role for PTPN14 in Hippo signal integration


sentences: On the normative advantages of dopamine and striatal opponency for learning and choice


sentences: sDarken: Next generation genetically encoded fluorescent sensors for serotonin


sentences: Development, feasibility and potential effectiveness of community-based continuous mass dog vaccination delivery strategies: lessons for optimization and replication


sentences: Minor differences in peptide presentation between chicken MHC class I molecules can explain differences in disease susceptibility


sentences: Quantitative Analysis of Transcriptome Dynamics Provides Novel Insights into Developmental State Transitions


sentences: Life history diversity and signals of trade-offs in a large group of chloroviruses


sentences: Empirical study on software and process quality in bioinformatics tools


sentences: High throughput screen in a co-culture model to uncover therapeutic strategies to potentiate the cancer-inhibiting properties of the tumor-stroma in pancreatic cancer

labels: cancer biology


sentences: sstar: A Python package for detecting archaic introgression from population genetic data with S*


sentences: In vivo CRISPR screens reveal SCAF1 and USP15 as novel drivers of pancreatic cancer


sentences: In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer


sentences: Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling


sentences: Wnt and BMP signaling enhance melanocyte regeneration and suppress melanoma cell migration


sentences: Genome-resolved metaproteomics decodes the microbial and viral contributions to coupled carbon and nitrogen cycling in river sediments


sentences: Metal Coordinating Inhibitors of Rift Valley Fever virus Replication


sentences: Synapse-type-specific competitive Hebbian learning forms functional recurrent networks


sentences: A robust Reeb graph model of white matter fibers with application to Alzheimer's disease progression


sentences: Patterned apoptosis modulates local growth and tissue shape in a fast-growing epithelium


sentences: The extinction of threatened species by anthropogenic threats endangers the functional diversity of turtles and crocodiles


sentences: Improved basic cytogenetics challenges holocentricity of butterfly chromosomes


sentences: Assessment of genetic diversity and SNP marker development within peanut germplasm in Taiwan by RAD-seq


sentences: High-frame-rate analysis of knee cartilage deformation by spiral dualMRI and relaxation mapping

labels: bioengineering


sentences: cgRNASP: coarse-grained statistical potentials with residue separation for RNA structure evaluation

labels: biophysics


sentences: Profiling Mouse Brown and White Adipocytes to Identify Metabolically Relevant Small ORFs and Functional Microproteins

labels: systems biology


sentences: Rhythm of relationships in a social fish over the course of a full year in the wild


sentences: Wireless networks of injectable microelectronic stimulators based on rectification of volume conducted high frequency currents


sentences: dialogi: Utilising NLP with chemical and disease similarities to drive the identification of Drug-Induced Liver Injury literature


sentences: FPGA Acceleration of GWAS Permutation Testing


sentences: Selective Control of Parasitic Nematodes Using Bioactivated Nematicides

labels: pharmacology and toxicology


sentences: A fungal endophyte-generated nucleoside signal regulates host cell death and promotes root colonization


sentences: BrainQCNet: a Deep Learning attention-based model for multi-scale detection of artifacts in brain structural MRI scans


sentences: A novel automated morphological analysis of microglia activation using a deep learning assisted model


sentences: Synapse type-specific molecular nanoconfigurations of the presynaptic active zone in the hippocampus identified by systematic nanoscopy


sentences: Coherent network oscillations regulate quiescence and behavioral responsiveness in Drosophila


sentences: B cells are addicted to immunoglobulin production in the ER


sentences: The AppNL-G-F mouse model of Alzheimer's disease is refractory to regulatory T cell treatment


sentences: The asymmetric ABA response on both sides of root tip is important for tomato root hydrotropism by mediating proton efflux and cell elongation

labels: ecology


sentences: Elevated human footprint on islands promotes both introduction and extinction probability of insular reptiles at opposite ends of geographic, evolutionary and ecological continua


sentences: Positive selection of senescence through increased evolvability: ageing is not a by-product of evolution.


sentences: Black Queen Hypothesis, partial privatization, andquorum sensing evolution


sentences: A re-emerging arbovirus in livestock in China: Early genomic surveillance and phylogeographic analysis


sentences: Sulfur-mediated chalcogen versus hydrogen bonds in proteins: a seesaw effect in the conformational space


sentences: Human myelin proteolipid protein structure and lipid bilayer stacking


sentences: Tetrasulfide Bridge (TTSB) Formation: an Extraordinary Intermediate Structure in the Architecture and Dynamics of the HIV-1s gp120 molecule


sentences: A low-power communication scheme for wireless, 1000 channel brain-machine interfaces


sentences: OncoPubMiner: A platform for oncology publication mining


sentences: Testing microbiome associations with censored survival outcomes at both the community and individual taxon levels


sentences: AttnPacker: An end-to-end deep learning method for rotamer-free protein side-chain packing


sentences: A method to predict 3D structural ensembles of chromatins from pairwise distances: Applications to Interphase Chromosomes and Structural Variants


sentences: DeepSCM: an efficient convolutional neural network surrogate model for the screening of therapeutic antibody viscosity


sentences: Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability


sentences: Human endogenous retrovirus activation contributes to biliary atresia pathogenesis through re-education of resident macrophages


sentences: A Nematode-Selective Potentiator of Organophosphate and Carbamate Agrochemicals


sentences: Comparing flickering and pulsed chromatic pupil light responses

labels: physiology


sentences: Physiological trait networks enhance understanding of crop growth and water use in contrasting environments

labels: plant biology


sentences: A comprehensive mechanistic model of adipocyte signaling with layers of confidence


sentences: A Spatiotemporal Reconstruction of the C. elegans Pharyngeal Cuticle Reveals a Structure Rich in Phase-Separating Proteins


sentences: Comparative analysis of total alpha-synuclein (αSYN) immunoassays reveals that they do not capture the diversity of modified αSYN proteoforms


sentences: Chemogenetic enhancement of cAMP signaling renders hippocampal synaptic plasticity resilient to the impact of acute sleep deprivation


sentences: Neurons in inferior temporal cortex are sensitive to motion trajectory during degraded object recognition


sentences: Dimensionality reduction of calcium-imaged neuronal population activity


sentences: Implicit sensorimotor adaptation is preserved in Parkinson's Disease


sentences: Circuit analysis of the Drosophila brain using connectivity-based neuronal classification reveals organization of key information processing pathways


sentences: Antecedent effect models as an exploratory rather than predictive tool to understand the response of plant populations to climate drivers


sentences: Urbanization and green corridors influence reproductive success and pollinators of common milkweed


sentences: Functional universality in slow-growing microbial communities arises from thermodynamic constraints


sentences: Reproductive barriers and genomic hotspots of adaptation during allopatric species divergence


sentences: A self-adjusting, progressive shock magnitude procedure to investigate resistance to punishment: characterization in male and female rats

labels: animal behavior and cognition


sentences: Strength-mass scaling law governs mass distribution inside honey bee swarms


sentences: GRAPE: Genomic Relatedness Detection Pipeline


sentences: Tension anisotropy drives phenotypic transitions of cells via two-way cell-ECM feedback


sentences: Generative and interpretable machine learning for aptamer design and analysis of in vitro sequence selection


sentences: Automated patch clamp screening of amiloride and 5-N,N-hexamethyleneamiloride (HMA) analogs identifies 6-iodoamiloride as a potent acid-sensing ion channel inhibitor.


sentences: Is Melanopsin Activation Affecting Large Field Color Matching Functions?


sentences: Phyllochron duration and changes through rice development shape the vertical leaf size profile


sentences: Impairments in fear extinction memory and basolateral amygdala plasticity in the TgF344-AD rat model of Alzheimer's disease are distinct from non-pathological aging.


sentences: Associations between locus coeruleus MRI contrast and physiological responses to acute stress in younger and older adults


sentences: Examination of diurnal variation and sex differences in hippocampal neurophysiology and spatial memory


sentences: Sample size requirement for achieving multisite harmonization using structural brain MRI features


sentences: E-cigarette vapour from base components propylene glycol and vegetable glycerine inhibits inflammatory response in macrophages and epithelial cells


sentences: A minimal growth medium for Pseudomonas azotoformans associated with insect gut


sentences: Molecular architecture of the TasA biofilm scaffold in Bacillus subtilis


sentences: Gram-negative Antimicrobial spectrum of Ulmus pumila


sentences: Inorganic sulfur fixation via a new homocysteine synthase allows yeast cells to cooperatively compensate for methionine auxotrophy

labels: molecular biology


sentences: Diffusional variance-determined stochastic translation efficiency


sentences: Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events


sentences: Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility

labels: evolutionary biology


sentences: Shared and distinct genetic etiologies for different types of clonal hematopoiesis

labels: genetics


sentences: A Microengineered Brain-Chip to Model Neuroinflammation in Humans


sentences: High axial-resolution optical stimulation of neurons in vivo via two-photon optogenetics with speckle-free beaded-ring pattern


sentences: Deep brain stimulation pulse sequences to optimally modulate frequency-specific neural activity


sentences: Real-time denoising of fluorescence time-lapse imaging enables high-sensitivity observations of biological dynamics beyond the shot-noise limit


sentences: LIPA-driven hydrolysis of cholesteryl arachidonate promotes cancer metastasis via NF-κB


sentences: Invasiveness of Cancer Populations in a Two-dimensional Percolation cluster: a Stochastic Mathematical Approach


sentences: Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic arachidonate cascade in streptozotocin-induced diabetic rats


sentences: Culture media, DMSO and efflux affect the antibacterial activity of cisplatin and oxaliplatin


sentences: Genome-wide analysis of PTR/POT transporters in Candida species and their functional characterization in the newly emerged pathogen Candida auris


sentences: Revisiting Ancient Polyploidy in Leptosporangiate Ferns


sentences: Variation in spontaneous mutation rate and spectrum across the genome of Neurospora crassa


sentences: LANTSA: Landmark-based transferable subspace analysis for single-cell and spatial transcriptomics

labels: bioinformatics


sentences: High-throughput Production of Diverse Xenobiotic Metabolites with P450-transduced Huh7 Hepatoma Cell Lines


sentences: Boosting transformation in wheat by BBM-WUS


sentences: Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types and cortical subnetworks

labels: neuroscience


sentences: N-Terminomic Changes of Neurons During Excitotoxicity Reveals Proteolytic Events Associated with Synaptic Dysfunctions and Potential Targets for Neuroprotection


sentences: A consensus protocol for the recovery of mercury methylation genes from metagenomes


sentences: A surface pocket in the cytoplasmic domain of the herpes simplex virus fusogen gB controls membrane fusion


sentences: A new insight into RecA filament regulation by RecX from the analysis of conformation-specific interactions


sentences: Prior selection affects phenotypic and transcriptional response to hypoxia


sentences: Landing manoeuvres predict roost-site preferences in bats


sentences: Asymmetrical lineage introgression and recombination in populations of Aspergillus flavus: implications for biological control


sentences: Graph-based algorithms for phase-type distributions


sentences: Organellar transcripts dominate the cellular mRNA pool across plants of varying ploidy levels


sentences: Accelerating PERx Reaction Enables Covalent Nanobodies for Potent Neutralization of SARS-Cov-2 and Variants

labels: synthetic biology


sentences: Development of a ferritin-based nanoparticle vaccine against the SARS-CoV-2 Omicron variant

labels: microbiology


sentences: The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes


sentences: Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events


sentences: A broad and potent neutralization epitope in SARS-related coronaviruses


sentences: Discovery of anti-SARS-CoV-2 molecules using structure-assisted repurposing approach targeting N-protein


sentences: Dual inhibition of vacuolar ATPase and TMPRSS2 is required for complete blockade of SARS-CoV-2 entry into cells

labels: cell biology


sentences: The triadic structure of personality space in the house mouse resembles that of species with known personality badges; suggesting reciprocal hierarchies are an evolutionary motif with mixed strategies being more common


sentences: Parchment Glutamine Index (PQI): A novel method to estimate glutamine deamidation levels in parchment collagen obtained from low-quality MALDI-TOF data


sentences: Antiviral State of CD1c+ cDC contributes to Increased Maturation and Activation of Cytotoxic Natural Killer cells in Sjogrens Syndrome

labels: immunology


sentences: Immunization with recombinant accessory protein-deficient SARS-CoV-2 protects against lethal challenge and viral transmission


sentences: Combination treatment can hinder the evolution of resistance to antimicrobial peptides


sentences: STOmicsDB: a database of Spatial Transcriptomic data

labels: genomics


sentences: Two types of hand withdraw movement to place food in the mouth mediated by somatosensation in 22-species of strepsirrhines


sentences: Do males know? Evidence-driven rainmaking of male bonobos to meet fertile phase of females


sentences: In vitro engineering of the lung alveolus

labels: bioengineering


sentences: Step length and the extrapolated center of mass co-vary to stabilize the margin of stability in the anterior-posterior direction during unobstructed and obstructed walking


sentences: Porous yet Dense matrices: using ice to shape collagen 3D cell culture systems with increased physiological relevance


sentences: kb_DRAM: Annotating and functional profiling of genomes with DRAM in KBase


sentences: Palo: Spatially-aware color palette optimization for single-cell and spatial data


sentences: Planemo: a command-line toolkit for developing, deploying, and executing scientific data analyses


sentences: Blood-based transcriptomic signature panel identification for cancer diagnosis: Benchmarking of feature extraction methods


sentences: Novel tuberculosis combination regimens of two and three-months therapy duration


sentences: Effect of GDF15 on acetaminophen (APAP)-induced liver injury in mice


sentences: Hippocampal theta and episodic memory


sentences: Astrocyte mitochondria produce nitric oxide from nitrite to modulate cerebral blood flow during brain hypoxia


sentences: Virgin Birth: A genetic basis for facultative parthenogenesis


sentences: Neutrophil Peptidylarginine Deiminase 4 is Essential for Detrimental Age-related Cardiac Remodeling and Dysfunction in Mice


sentences: The sunflower WRINKLED1 transcription factor regulates fatty acid biosynthesis genes through an AW box binding sequence with a particular base bias


sentences: Interferon-induced lysosomal membrane permeabilization causes cDC1-deserts in tumors.


sentences: Arctic phytoplankton spring bloom diversity across the marginal ice zone in Baffin Bay


sentences: Expression and Purification of BsaXI Restriction Endonuclease and Engineering New Specificity from BsaXI Specificity (S) Subunit


sentences: Parsing the role of NSP1 in SARS-CoV-2 infection


sentences: STORM-seq Reveals Differentiation Trajectories of Primary Human Fallopian Tube Epithelium


sentences: Oxidative phosphorylation pathway disruption is an alternative pathological mechanism leading to Diamond-Blackfan anemia


sentences: Imaging tools generated by CRISPR/Cas9 tagging reveal cytokinetic diversity in mammalian cells


sentences: Endosomes deliver ceramide phosphoethanolamine with unique acyl chain anchors to the cleavage furrow during male meiotic cytokinesis


sentences: TNIP1 inhibits Mitophagy via interaction with FIP200 and TAX1BP1


sentences: Genetic mapping of multiple metabolic traits identifies novel genes for adiposity, lipids and insulin secretory capacity in outbred rats


sentences: Deterioration of the human transcriptome with age due to increasing intron retention and spurious splicing


sentences: Molecular docking between human TMPRSS2 and the serine protease Kunitz-type inhibitor rBmTI-A

labels: biochemistry


sentences: Hypoxia-inducible factor 1 signaling drives placental aging and can elicit inflammatory changes in uterine myocytes


sentences: Peritoneal M2 macrophage-derived extracellular vesicles as natural multi-target nanotherapeutics to attenuate cytokine storm after severe infections


sentences: Intratumoral Recall of Childhood Vaccine-Specific CD4+ T cells Coordinates Type I and II Antitumor Immunity


sentences: Modulation of the extracellular matrix by Streptococcus gallolyticus subsp. gallolyticus and importance in cell proliferation


sentences: Revealing the microbial heritage of traditional Brazilian cheeses through metagenomics


sentences: Contribution of the Golgi apparatus in morphogenesis of a virus induced cytopathic vacuolar system


sentences: Group II Intron-Like Reverse TranscriptasesFunction in Double-Strand Break Repair by Microhomology-Mediated End Joining


sentences: Opposing effects of calcium stress in human muscle: defective glucose utilization leading to diabetes vs. stress-adaptive effects of a junctophilin fragment


sentences: Lnc956-TRIM28-HSP90B1 complex on replication forks promotes CMG helicase retention to ensure stem cell genomic stability and embryogenesis


sentences: Base editing derived models of human WDR34 and WDR60 disease alleles replicate retrograde IFT and hedgehog signaling defects and suggest disturbed Golgi protein transport


sentences: Discovery of a novel jingmenvirus in Australian sugarcane Soldier fly (Inopus flavus) larvae


sentences: Hemin availability induces coordinated DNA methylation and gene expression changes in Porphyromonas gingivalis


sentences: Structural insights into the regulation of acetylation-dependent genome condensation


sentences: Mitochondrial Redox Adaptations Enable Aspartate Synthesis in SDH-deficient Cells


sentences: Validation of a small molecule inhibitor of PDE6D-RAS interaction with potent anti-leukemic effects

labels: cancer biology


sentences: EPI-589, a redox-active neuroprotectant, potently protects cultured cells from oxidative stress and alleviates symptomatic and pathological progression of motor neuron disease in the wobbler mouse

labels: pharmacology and toxicology


sentences: Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy


sentences: Structural basis for ultrapotent neutralization of human metapneumovirus


sentences: Transcriptome profiling of barley and tomato shoot and root meristems unravels physiological variations underlying photoperiodic sensitivity

labels: developmental biology


sentences: First assessment of Iranian pomegranate germplasm using targeted metabolites and morphological traits to develop the core collection and modeling of the current and future spatial distribution under climate change conditions

labels: plant biology


sentences: Formulation of substrates with agricultural and forestry wastes for Camellia oleifera Abel seedling cultivation


sentences: Altered integration of excitatory inputs onto the basal dendrites of layer 5 pyramidal neurons in a mouse model of Fragile X Syndrome


sentences: A Genetic History of Continuity and Mobility in the Iron Age Central Mediterranean


sentences: An integrated single-cell atlas of the skeleton from development through adulthood


sentences: Ontogeny of oscillatory slow-wave and neuronal population activity in human iPSC-3D cortical circuits


sentences: Dissecting neural computations of the human auditory pathway using deep neural networks for speech


sentences: Individual neurophysiological signatures of spontaneous rhythm processing


sentences: The Regulatory Mendelian Mutation score for GRCh38


sentences: Mutational footprint of platinum chemotherapy in a secondary thyroid cancer


sentences: Connectivity in Large-Scale Resting State Brain Networks is Related to Motor Learning: a High-Density EEG Study


sentences: Vascular dysregulation following SARS-CoV-2 infection involves integrin signaling through a VE-Cadherin mediated pathway


sentences: Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model.


sentences: Omicron variant of SARS-COV-2 gains new mutations in New Zealand and Hong Kong


sentences: Structural basis of Omicron immune evasion: A comparative computational study of Spike protein-Antibody interaction.

labels: biophysics


sentences: Neutrophils initiate the destruction of the olfactory epithelium during SARS-CoV-2 infection in hamsters


sentences: Pulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA.1 (B.1.1.529) variant in Syrian golden hamsters


sentences: Sensorimotor transformation underlying odor-modulated locomotion in walking Drosophila


sentences: Motor Cortex Excitability in Chronic Low Back Pain


sentences: APOE ϵ2 vs APOE ϵ4 dosage shows sex-specific links to hippocampus-default network subregion co-variation


sentences: Dynamic and selective engrams emerge with memory consolidation


sentences: A large and rich EEG dataset for modeling human visual object recognition


sentences: Place cells are non-randomly clustered by field location in CA1 hippocampus


sentences: Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease severity and lung inflammation


sentences: Dual spatially resolved transcriptomics for SARS-CoV-2 host-pathogen colocalization studies in humans


sentences: A pathogenicity locus of Streptococcus gallolyticus subspecies gallolyticus


sentences: Halophilic bacteria Bacillus altitudinis MIM2 producing melanin isolated from Mundra port, Kutch, Gujarat, India


sentences: Broad-spectrum extracellular antiviral properties of Cucurbiturils


sentences: High resolution reconstruction of a Jumbo bacteriophage infecting capsulated bacteria using hyperbranched tail fibers


sentences: Defining the genes required for survival of Mycobacterium bovis in the bovine host offers novel insights into the genetic basis of survival of pathogenic mycobacteria


sentences: Growth inhibition of Akkermansia muciniphila by a secreted pathobiont sialidase


sentences: On-Ramp: a tool for rapid, multiplexed validation of plasmids using nanopore sequencing

labels: molecular biology


sentences: Endogenous IL-10 Contributes to Wound Healing and Regulates Tissue Repair


sentences: A subpopulation of Talin 1 resides in the nucleus and regulates gene expression


sentences: Graph deep learning reveals multiple signal pathways activated in anti-citrullinated protein antibodies stimulated synoviocytes


sentences: Dual targeting of Saccharomyces cerevisiae Pso2 to mitochondria and the nucleus, and its functional relevance in the repair of DNA interstrand crosslinks


sentences: Expressed therapeutic protein yields are predicted by transiently transfected mammalian cell population


sentences: Integrated platform for multi-scale molecular imaging andphenotyping of the human brain


sentences: Genetic engineering of Acidithiobacillus ferridurans with CRISPR-Cas9/dCas9 systems


sentences: Exogenous application of dsRNA for the control of viruses in cucurbits


sentences: Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation

labels: systems biology


sentences: Overlap across psychotic disorders: A functional network connectivity analysis


sentences: Atypical small GTPase RABL3 interacts with RAB11 to regulate early ciliogenesis in human cells


sentences: Endocytosis is required for access of surface-bound cargo to the flagellar pocket of trypanosomes


sentences: Crumbs complex-directed apical membrane dynamics in epithelial cell ingression


sentences: Honeycomb crystallography: Experiment-theory approach for bee comb formation under geometric frustrations

labels: ecology


sentences: Sex chromosome differentiation via changes in the Y chromosome repeat landscape in African annual killifishes Nothobranchius furzeri and N. kadleci

labels: evolutionary biology


sentences: Detecting patterns of accessory genome coevolution in bacterial species using data from thousands of bacterial genomes


sentences: R-BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures


sentences: Mechanistic insight into the ATP hydrolysis cycle of tick-borne encephalitis virus helicase


sentences: Multi-level cellular and functional annotation of single-cell transcriptomes

labels: bioinformatics


sentences: QTLViewer: An interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations


sentences: Self-association features of NS1 proteins from different flaviviruses


sentences: Replacing bar graphs of continuous data with more informative graphics: Are we making progress?

labels: scientific communication and education


sentences: Cas9-Mediated Knockout of Ndrg2 Enhances the Regenerative Potential of Dendritic Cells for Wound Healing


sentences: The Use and Misuse of Composite Environmental Indices


sentences: Reproducibility problem with a proposed standard method to measure disinfection efficacy

labels: microbiology


sentences: Production of novel biosurfactant by a new yeast species isolated from Prunus mume Sieb. et Zucc.


sentences: Deep learning based feature extraction for prediction and interpretation of sharp- wave ripples

labels: neuroscience


sentences: Claudin5 protects the peripheral endothelial barrier in an organ and vessel type-specific manner

labels: cell biology


sentences: Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variability


sentences: Identifying the genes impacted by cell proliferation in proteomics and transcriptomics studies


sentences: Integration of multimodal data in the developing tooth reveals candidate dental disease genes


sentences: Decorating chromatin for enhanced genome editing using CRISPR-Cas9

labels: genetics


sentences: A modality independent proto-organization of human multisensory areas


sentences: Functional architecture of cerebral cortex during naturalistic movie-watching


sentences: Reciprocal representation of encoded features by cortical excitatory and inhibitory neuronal populations.


sentences: The development of efficient communication in the human connectome.


sentences: Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum supports social novelty preference


sentences: Tripartite extended amygdala - basal ganglia CRH circuit drives arousal and avoidance behaviour


sentences: Neonate personality affects early-life resource acquisition in a large social mammal


sentences: On the use of relative brain size


sentences: miR319-targeted TCP4/LANCEOLATE directly regulates OVATE and auxin responses to modulate tomato gynoecium patterning and fruit morphology


sentences: EXTERNAL CONTROL OF CANCER CELLULAR DYNAMICS USING ADAPTIVE MODEL PREDICTIVE CONTROL


sentences: Replication-dependent organisation constrains positioning of long DNA repeats in bacterial genomes

labels: genomics


sentences: Genomes of Two Flying Squid Species Provide Novel Sights into Adaptations of Cephalopods to Pelagic Life


sentences: Improved sensitivity and resolution of ATAC-seq differential DNA accessibility analysis


sentences: Allosteric activation of CRISPR-Cas12a requires the concerted movement of the bridge helix and helix 1 of the RuvC II domain

labels: biochemistry


sentences: The orphan ligand, Activin C, signals through activin receptor-like kinase 7


sentences: Interpreting the contributions of transcript features to protein abundance prediction models


sentences: Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells


sentences: Artificial Hsp100-mediated systems for re-localizing protein aggregates


sentences: Strain stiffening of the Ndc80 complex


sentences: Merging of ventral fibers at adhesions drives the remodeling of cellular contractile systems in fibroblasts.


sentences: Targeting A-Kinase Anchoring Protein 12 Phosphorylation in Hepatic Stellate Cells Regulates Liver Injury and Fibrosis in Mouse Models


sentences: Zfp281 inhibits the pluripotent-to-totipotent state transition in mouse embryonic stem cells


sentences: FGF10 triggers de novo alveologenesis in a BPD model: impact on the resident mesenchymal niche cells


sentences: CyberSco.Py: open-source software for event-based, conditional microscopy


sentences: Cellular redox metabolism is modulated by the distinct localization of cyclic nucleotide phosphodiesterase 5A isoforms


sentences: Aftiphilin regulation of myosin light chain kinase activity promotes actin dynamics and intestinal epithelial barrier function


sentences: A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease


sentences: KIF24 controls the clustering of supernumerary centrosomes in pancreatic ductal adenocarcinoma cells


sentences: Cell size and actin architecture determine force generation in optogenetically activated adherent cells


sentences: CDKL5 deficiency slows synaptic vesicle endocytosis


sentences: Dual role of an essential HtrA2/Omi protease in the human malaria parasite: maintenance of mitochondrial homeostasis and induction of apoptosis like cell death under cellular stress


sentences: Molecular Crowding Facilitates Bundling of IMPDH Polymers and Cytoophidium Formation


sentences: The X chromosome is a potential polarising signal for asymmetric cell divisions in meiotic cells of a nematode


sentences: Lipid-correlated alterations in the transcriptome are enriched in several specific pathways in the postmortem prefrontal cortex of Japanese patients with schizophrenia

labels: pathology


sentences: Concurrent separation of phase-locked and non-phase-locked activity


sentences: Geometrical factors determining dendritic domain intersection between neurons: a modeling study


sentences: Sharp wave ripples in macaque V1 and V4 are modulated by top-down visual attention


sentences: Integrated Diffusion Image Operator (iDIO): A tool for automated configuration and processing of diffusion MRI data


sentences: Regulation of presynaptic Ca2+ channel abundance at active zones through a balance of delivery and turnover


sentences: Beetles provide directed dispersal of viable spores of a keystone wood decay fungus


sentences: The chemical basis of metabolic interdependence in microbial communities


sentences: Eco-evolutionary dynamics of clonal multicellular life cycles


sentences: Little skate genome exposes the gene regulatory mechanisms underlying the evolution of vertebrate locomotion


sentences: Genetic affinities and adaptation of the South West coast populations of India


sentences: Assessing behavioral sex differences to chemical cues of predation risk while provisioning nestlings in a hole-nesting bird

labels: animal behavior and cognition


sentences: The physical properties of the stick insect pad secretion are independent of body size

labels: bioengineering


sentences: Neq2X7: a multi-purpose and open-source fusion DNA polymerase for advanced DNA engineering and diagnostics PCR


sentences: Development of a single layer microfluidic device for dynamic stimulation, culture and imaging of mammalian cells


sentences: Unleashing alternative polyadenylation analyses with REPAC


sentences: HCLC-FC: a novel statistical method for phenome-wide association studies


sentences: New β-propellers are continuously amplified from single blades in all major lineages of the β-propeller superfamily


sentences: Comparison and evaluation of data-driven protein stability prediction models


sentences: Identification of m6A and m5C RNA modifications at single-molecule resolution from Nanopore sequencing


sentences: iSparse kmeans: a two-step clustering approach for big dynamic functional network connectivity data


sentences: Hyperglycemic O-GlcNAc transferase activity drives cancer stem cell induction in TNBC

labels: cancer biology


sentences: Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies


sentences: High-fat diet promotes Acute Promyelocytic Leukemia through PPARδ-enhanced self-renewal of preleukemic progenitors


sentences: A Drosophila in vivo chemical screen reveals that combination drug treatment targeting MEK and DGKα mitigates Ras-driven polarity-impaired tumourigenesis.


sentences: Induction of promoter methylation and transcriptional gene silencing upon high pressure spraying of 24-nt small RNAs in Nicotiana benthamiana

labels: plant biology


sentences: Carbon dots boost dsRNA delivery in plants and increase local and systemic siRNA production


sentences: High salinity activates CEF and attenuates state transitions in both psychrophilic and mesophilic Chlamydomonas species


sentences: Remorin proteins serve as membrane topology scaffolds in plants


sentences: Epistatic Modifiers Influence the Expression of Continual Flowering in Strawberry


sentences: Increases in vein length compensate for leaf area lost to lobing in grapevine


sentences: Individualized Gaussian Process-based Prediction of Memory Performance and Biomarker Status in Ageing and Alzheimer's disease


sentences: Plakoglobin is a mechanoresponsive regulator of naïve pluripotency

labels: developmental biology


sentences: Decomposing predictability to identify dominant causal drivers in complex ecosystems


sentences: What are you lookin' at?: A role for sexual conflict in coevolution of female display signals and male sensory adaptations?


sentences: MR-DoC2: bidirectional causal modeling with instrumental variables and data from relatives


sentences: Exploring a diverse world of effector domains and amyloid signaling motifs in fungal NLR proteins


sentences: MiXcan: a Framework for Cell-Type-Specific Transcriptome-Wide Association Studies with an Application to Breast Cancer


sentences: MSclassifR: an R package for supervised classification of mass spectra with machine learning methods


sentences: Learning deep representations of enzyme thermal adaptation


sentences: Systematic evaluation of chromatin immunoprecipitation sequencing to study histone occupancy in dormancy transitions of grapevine buds


sentences: Predictable and stable epimutations induced during clonal propagation with embryonic transcription factors


sentences: Age-dependent lipid droplet-rich microglia worsen stroke outcome in old mice


sentences: Temporal dynamics of competition between statistical learning and episodic memory in intracranial recordings of human visual cortex


sentences: Dual STDP processes at Purkinje cells contribute to distinct improvements in accuracy and vigor of saccadic eye movements.


sentences: A conserved immune trajectory of recovery in hospitalized COVID-19 patients

labels: immunology


sentences: Size-selective mortality fosters evolutionary changes in collective learning across ontogeny and decision-making in zebrafish, Danio rerio

labels: ecology


sentences: Targeting an evolutionarily conserved "E-L-L" motif in the spike protein to develop a small molecule fusion inhibitor against SARS-CoV-2


sentences: Allosteric binders of ACE2 are promising anti-SARS-CoV-2 agents


sentences: Nitrogen and phosphorus deficiencies alter primary and secondary metabolites of soybean roots


sentences: A free classified advertising website is a high-risk unregulated source of domestic wild boar, pot-bellied pigs, and their hybrids with domestic swine in Canada: Implications for African Swine Fever Risk Preparedness


sentences: Neuroligin-3 in Dopamine Neurons Promotes Behavioral and Neurobiological Adaptations to Chronic Morphine Exposure


sentences: Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines


sentences: Direct detection of natural selection in Bronze Age Britain

labels: evolutionary biology


sentences: MePMe-seq: Antibody-free simultaneous m6A and m5C mapping in mRNA by metabolic propargyl labeling and sequencing


sentences: Long range electromagnetic effects drive protein-protein approaches: an egg of Coulomb


sentences: Molecular Dynamics simulation of TDP-43 RRM in the presence and absence of RNA

labels: biophysics


sentences: Quorum sensing as a mechanism to harness the wisdom of the crowds


sentences: Chlamydia trachomatis suppresses host cell store-operated Ca2+ entry and inhibits NFAT/calcineurin signaling


sentences: Is virulence phenotype evolution driven exclusively by Lr gene deployment in French Puccinia triticina populations?


sentences: Dynamic model of bovine brucellosis to investigate control strategies in endemic settings


sentences: A coevolution experiment reveals parallel mutations in the AcrA-AcrB-TolC efflux pump that contributes to bacterial antibiotic resistance


sentences: Tales of Two α-Carboxysomes: the Structure and Assembly of Cargo Rubisco


sentences: Rapid detection of Staphylococcus aureus and Streptococcus pneumoniae by real-time analysis of volatile metabolites


sentences: Phylogenetic analysis of human parainfluenza type 3 virus strains responsible for the outbreak during the COVID-19 pandemic in Seoul, South Korea


sentences: Zika virus NS4A hijacks host ANKLE2 to promote viral replication

labels: molecular biology


sentences: ANTARCTIC FUNGI: A BIO-SOURCE ALTERNATIVE TO PRODUCE POLYUNSATURATED FATTY ACIDS (PUFAs)


sentences: Hibernation shows no apparent effect on germline mutation rates in grizzly bears


sentences: Plasmid stability in fluctuating environments:population genetics of multi-copy plasmids


sentences: Genome-wide binding of Drosophila Mask reveals its role in maintenance of gene activation by Trithorax group


sentences: In depth exploration of the alternative proteome of Drosophila melanogaster


sentences: A single-cell clusters similarity measure for different batches, datasets, and samples

labels: bioinformatics


sentences: Single cells tell their own story: An updated framework for understanding stochastic variations in cell cycle progression in bacteria


sentences: Integrative DNA methylation analysis of pediatric brain tumors reveals tumor type-specific developmental trajectories and epigenetic signatures of malignancy


sentences: Targeting Cblb-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cells responses


sentences: PeroxiHUB: a modular cell-free biosensing platform using H2O2 as signal integrator

labels: synthetic biology


sentences: Strain-specific alterations in gut microbiome and host immune responses elicited by Bifidobacterium pseudolongum

labels: microbiology


sentences: A potential interacting network identified by quantitative proteomics for the sole adenylyl cyclase Cyr1 of Candida albicans


sentences: A novel conserved protein in Streptococcus agalactiae, BvaP, is important for vaginal colonization and biofilm formation


sentences: Chemical and genetic screens identify new regulators of tetracycline-inducible gene expression system in mammalian cells


sentences: Phase separated ribosome nascent chain complexes paused in translation are capable to continue expression of proteins playing role in genotoxic stress response upon DNA damage


sentences: Uterine injury during diestrus leads to embryo spacing defects and perturbations in the COX pathway in subsequent pregnancies


sentences: Leaf bacterial community structure and variation in wild ruderal plants are shaped by the interaction of host species and defense chemistry with environment


sentences: Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes


sentences: The DNA methylation landscape of the human oxytocin receptor gene (OXTR): Recommendations for future research


sentences: AHR agonist ITE boosted PD1 antibodys effects by inhibiting myeloid-derived cells suppressive cells in an orthotopic mouse glioma model


sentences: Validating methods to eradicate Select Agent and phylotype I Ralstonia solanacearum strains reveals that growth in planta increases bacterial stress tolerance


sentences: Genetic interaction analysis reveals that Cryptococcus neoformans utilizes multiple acetyl-CoA-generating pathways during infection


sentences: Multigrate: single-cell multi-omic data integration


sentences: Multimodal spatiotemporal phenotyping of human organoid development

labels: systems biology


sentences: Hypothalamic-pituitary-adrenal axis dysfunction worsens epilepsy outcomes and increases SUDEP risk

labels: neuroscience


sentences: Proportional intracranial volume correction differentially biases behavioral predictions across neuroanatomical features and populations


sentences: Chimpanzees organize their social relationships like humans


sentences: Medial septum glutamate neurons are essential for spatial goal-directed memory


sentences: Invasion genetics of the longhorn crazy ant: the global expansion of a double-clonal reproduction system


sentences: Selection on the fly: short term adaptation to an altered sexual selection regime in Drosophila pseudoobscura


sentences: Coevolution of Patch Selection in Stochastic Environments


sentences: Inbreeding depression in an outbred nine-spined stickleback (Pungitius pungitius) population


sentences: Hybrid-derived weedy rice maintains adaptive combinations of alleles associated with seed dormancy


sentences: Evolution of transposable element-derived enhancer activity

labels: genetics


sentences: minute: A MINUTE-ChIP data analysis workflow


sentences: MHC-I binding affinity derived metrics fail to predict tumor specific neoantigen immunogenicity


sentences: Effect of ambient fluid rheology on oscillatory instabilities in filament-motor systems


sentences: Pharmacokinetics of Sustained-Release Buprenorphine and Extended-Release Buprenorphine in Mice with Surgical Catheterization

labels: pharmacology and toxicology


sentences: Does ankle push-off correct for errors in anterior-posterior foot placement relative to center-of-mass state?

labels: physiology


sentences: Adenosine A1R/A3R Agonist AST-004 Reduces Brain Infarction in Mouse and Rat Models of Acute Ischemic Stroke


sentences: Mixture of Learning Strategies Underlies Rodent Behavior in Dynamic Foraging


sentences: The Influence of Neural activity and Neural Cytoarchitecture on Cerebrovascular Arborization: A Computational Model


sentences: Selective V1-to-V4 communication of attended stimuli mediated by attentional effects in V1


sentences: Brain Capillary Pericytes are Metabolic Sentinels that Control Blood Flow through KATP Channel Activity


sentences: Spontaneous myocarditis in mice predisposed to autoimmune disease: Including Vaccination-induced onset


sentences: A novel method accounting for predictor uncertainty and model transferability of invasive species distribution models


sentences: Functional Assays Reclassify Suspected Splice-Altering Variants of Uncertain Significance in Mendelian Channelopathies


sentences: A comprehensive dimensional reduction framework to learn single-cell phenotypic topology uncovers T cell diversity


sentences: SIMMAM 3.0 - Updating the Toolbox for the Conservation of Marine Mammals


sentences: Photons guided by axons may enable backpropagation-based learning in the brain


sentences: Angiotensin blockade enhances motivational reward learning via enhancing ventral striatal prediction error and frontostriatal communication


sentences: Glassy phase in dynamically-balanced neural networks


sentences: Generation and proof-of-concept for allogeneic CD123 CAR-Delta One T (DOT) cells in Acute Myeloid Leukemia


sentences: SLC15A4 favors inflammasome function via mTORC1 signaling and autophagy restraint in dendritic cells


sentences: Mutation-Attention (MuAt): deep representation learning of somatic mutations for tumour typing and subtyping

labels: genomics


sentences: Mapping Multiple Factors Mediated Chromatin Interactions to Assess Regulatory Network and Dysregulation of Lung Cancer-Related Genes


sentences: Limited effects of age on the use of the ankle and counter-rotation mechanism in the sagittal plane

labels: bioengineering


sentences: Probabilistic Brain Extraction in MR Images via Conditional Generative Adversarial Networks


sentences: Fluximplied: A novel approach integrates rate limiting steps and differential expression for pathway analysis


sentences: UniFuncNet: a flexible network annotation framework


sentences: Non-ribosomal peptide synthetase domain boundary identification and new motifs discovery based on motif-intermotifs standardized architecture


sentences: The identification of two newly discovered fluorescent proteins in human glioblastoma

labels: cancer biology


sentences: Heterogeneous multimeric metabolite ion species observed in LC-MS based metabolomics data sets


sentences: Model-guided design of the diversity of a synthetic human gut community


sentences: Glucagon-like peptide-1 receptor differentially controls mossy cell activity across the dentate gyrus longitudinal axis


sentences: Microarray profiling of hypothalamic gene expression changes in Huntington's disease mouse models


sentences: Optogenetic stimulation of medial septal glutamatergic neurons modulates theta-gamma coupling in the hippocampus


sentences: Developmental phenomics suggests that H3K4 monomethylation catalyzed by Trr functions as a phenotypic capacitor

labels: developmental biology


sentences: Targeted deletion of uterine glandular Foxa2 induces embryonic diapause in mice


sentences: Noninvasive stimulation of the ventromedial prefrontal cortex modulates rationality of human decision-making


sentences: The pyruvate dehydrogenase complex regulates mitophagic selectivity independently of its catalytic activity

labels: cell biology


sentences: Long-term T cell perturbations and waning antibody levels in individuals needing hospitalization for COVID-19

labels: immunology


sentences: The effect of waning on antibody levels and memory B cell recall following SARS-CoV-2 infection or vaccination


sentences: A novel anti-PD-L1/IL-15 immunocytokine overcomes resistance to PD-L1 blockade and elicits potent antitumor immunity


sentences: Broad neutralization of SARS-CoV-2 variants by circular mRNA producing VFLIP-X spike in mice


sentences: High-resolution secretory timeline from vesicle formation at the Golgi to fusion at the plasma membrane in S. cerevisiae


sentences: Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation


sentences: AtEH/Pan1 proteins drive phase separation of the TPLATE complex and clathrin polymerisation during plant endocytosis


sentences: Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations


sentences: Substrate trapping approach identifies TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes


sentences: En1 and Lmx1b do not recapitulate embryonic dorsal-ventral limb patterning functions during mouse digit tip regeneration


sentences: Sea anemone Frizzled receptors play partially redundant roles in the oral-aboral axis patterning


sentences: Differential expression of Nanog 3UTR and coding region mRNA components defines an embryonic stem cell niche


sentences: Inherent dynamics of maltose binding protein (MBP) are immune to the native environment.


sentences: Gill developmental program in the teleost mandibular arch


sentences: A non-invasive method for time-lapse imaging of microbial interactions and biofilm dynamics


sentences: A bipartite, low-affinity roadblock domain-containing GAP complex regulates bacterial front-rear polarity


sentences: Acute Cytomegalovirus Infection Modulates the Intestinal Microbiota and Targets Intestinal Epithelial Cells


sentences: Transcriptome analysis of alcohol dependence and stress interactions in the nucleus of the solitary tract


sentences: Arginine 65 methylation of Neurogenin 3 by PRMT1 is a prerequisite for development of hESCs into pancreatic endocrine cells


sentences: Evaluating the potential benefits and pitfalls of combining protein and expression quantitative trait loci in evidencing drug targets


sentences: Structure and functional mapping of the KRAB-KAP1 repressor complex

labels: biochemistry


sentences: Eight week dietary inclusion of nitrite-containing frankfurter exacerbates colorectal cancer pathology, increases oxidative stress, alters metabolism and causes gut dybiosis in APCmin mice


sentences: Structure of a Rad52 homolog from bacteriophage in complex with a novel duplex intermediate of DNA annealing


sentences: Groundwater metabolome responds to recharge in fractured sedimentary strata


sentences: Visualizing the Transiently Populated Closed-State of Human HSP90 ATP Binding Domain

labels: biophysics


sentences: A microfluidic platform to investigate the role of mechanical constraints on tissue reorganization


sentences: Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer


sentences: Multivalent, Bispecific ????B7-H3-????CD3 Chemically Self-Assembled Nanorings Direct Potent T-cell Responses Against Medulloblastoma


sentences: Stress-tolerant, recyclable, and autonomously renewable biocatalyst platform enabled by engineered bacterial spores


sentences: Lineage tracing via associative chromosome/plasmid barcoding with siBar


sentences: The faecal microbiome of the wild European badger Meles meles; a comparison against other wild omnivorous mammals from across the globe


sentences: New features of micro-RNA regulation of mRNA translation and stability revealed by expression of targeted or not targeted reporter genes

labels: molecular biology


sentences: Identification of Aspergillus niger aquaporins involved in hydrogen peroxide signaling


sentences: The Arabidopsis Hop1 homolog ASY1 mediates cross-over assurance and interference


sentences: The DeepFaune initiative: a collaborative effort towards the automatic identification of the French fauna in camera-trap images

labels: ecology


sentences: clampFISH 2.0 enables rapid, scalable amplified RNA detection in situ


sentences: Rational design of Cas9 ribonucleoprotein with a "gRNA-shRNA" for multidimensional genome manipulation and enhanced homology-directed repair


sentences: TidyMass: An Object-oriented Reproducible Analysis Framework for LC-MS Data

labels: bioinformatics


sentences: Proteome reallocation enables the selective de novo biosynthesis of non-linear, branched-chain acetate esters

labels: synthetic biology


sentences: Structure of dynein-dynactin on microtubules shows tandem recruitment of cargo adaptors


sentences: A correlational study between microstructural, macrostructural and functional age-related changes in the human visual cortex


sentences: Effects of different environmental intervention durations on the intestinal mucosal barrier and the brain-gut axis in rats with colorectal cancer


sentences: Fgf8 dosage regulates jaw shape and symmetry through pharyngeal-cardiac tissue relationships


sentences: Single-cell RNA sequencing of conditional 	Pten knockout neurons in mice


sentences: Distinct cortical responses to Auditory Statistics: pre-attentive discriminations based on local and global representations


sentences: Mesoaccumbal glutamate neurons drive reward via glutamate release, but aversion via dopamine co-release


sentences: A brain-wide analysis maps structural evolution to distinct anatomical modules


sentences: Surface motility favors co-dependent interaction between Pseudomonas aeruginosa and Burkholderia cenocepacia

labels: microbiology


sentences: Genomics epidemiology analysis reveals hidden signatures of drug resistance in Mycobacterium tuberculosis


sentences: Brain-wide screen of prelimbic cortex inputs reveals a functional shift during early fear memory consolidation

labels: neuroscience


sentences: Circulating miR-30b-5p is up regulated in Cavalier King Charles Spaniels affected by early myxomatous mitral valve disease


sentences: Genomic analyses identify key molecules and significant signaling pathways in Sorafenib treated hepatocellular cancer cells


sentences: Tempo: an unsupervised Bayesian algorithm for circadian phase inference in single-cell transcriptomics


sentences: The Trichloroethylene Metabolite S-(1,2-dichlorovinyl)-l-cysteine Inhibits Lipopolysaccharide-induced Transcriptomic Inflammation Pathways and Cytokine Secretion in a Macrophage Cell Model


sentences: Feature-based attention multiplicatively scales the fMRI-BOLD contrast-response function


sentences: NFAT5 induction by the tumor microenvironment enforces CD8 T cell exhaustion


sentences: Are trapping data still suited for home range estimation? An analysis with various estimators, asymptotic models and data ordering procedures


sentences: The use of pigs vocalisation structure to assess the quality of human-pig relationship

labels: animal behavior and cognition


sentences: Cavitation Induced Fracture of Intact Brain Tissue


sentences: A systematic comparison of current bioinformatic tools for glycoproteomics data


sentences: Unsupervised discovery of tissue architecture in multiplexed imaging


sentences: Adversarial attacks and adversarial robustness in computational pathology


sentences: metaPathwayMap: A tool to predict metabolic pathway neighborhoods from structural classes of untargeted metabolomics peaks


sentences: Dynamic play between human N-α-acetyltransferase D and H4-mutant histones: Molecular dynamics study


sentences: Dual blockade of misfolded alpha-sarcoglycan degradation by bortezomib and givinostat combination

labels: pharmacology and toxicology


sentences: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight in obese mice


sentences: Like host, like parasite: intraspecific divergence in a polystomatid flatworm parasite across South Africa echoes that of its frog host

labels: zoology


sentences: Electroencephalography-derived functional connectivity in sensorimotor networks in Stroke and Multiple Sclerosis Fatigue


sentences: Sst+ GPi output neurons provide direct feedback to key nodes of the basal ganglia and drive behavioral flexibility.


sentences: Microglial P2Y12 mediates chronic stress-induced synapse loss in the prefrontal cortex and associated behavioral consequences in male mice


sentences: How Hippocampus Solves Inverse Problems: A Circuit Hypothesis


sentences: Comparable theta phase coding dynamics along the transverse axis of CA1


sentences: A flexible and versatile system for multicolor fiber photometry and optogenetic manipulation


sentences: Thermoregulatory Dynamics Reveal Sex-Specific Inflammatory Responses to Experimental Autoimmune Encephalomyelitis in Mice: Implications for Multiple Sclerosis-Induced Fatigue in Females


sentences: Saturated reconstruction of living brain tissue


sentences: Geometry of spiking activity in early visual cortex: a Topological Data Analytic approach


sentences: Glocal dendritic spikes: variation in branch activity during dendritic spiking indicates multiple functional units in the pyramidal neuron apical tuft


sentences: Axisymmetric diffusion kurtosis imaging with Rician bias correction: A simulation study


sentences: T cell migration requires ion and water influx to regulate actin polymerization


sentences: VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome


sentences: Sex and size matter: foraging ecology of offshore harbour porpoises in waters around Greenland


sentences: Engineering ecologically complementary rhizosphere probiotics using consortia of specialized bacterial mutants


sentences: Beyond inappropriate fire regimes: a synthesis of fire-driven declines of threatened mammals in Australia


sentences: Xanthomonas indica sp. nov., a non-pathogenic bacterium isolated from healthy rice (Oryza sativa) seeds from India

labels: evolutionary biology


sentences: Transcriptional control of the lacZ promoter is under directional and diversifying selection


sentences: Case-only rare variant analysis of severe alcohol dependence (AD) using a multivariate hierarchical gene clustering approach.

labels: genetics


sentences: QTLs analysis for cold tolerance in rice (Oryza sp.) at the seedling stage using F2 population developed from cross between the genotypes NERICA L-19 and Diamante


sentences: DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types


sentences: Integrated protein and transcriptome high-throughput spatial profiling

labels: genomics


sentences: Integration of visual and antennal mechanosensory feedback during head stabilization in hawkmoths


sentences: Optimization of the precursor supply for an enhanced FK-506 production in Streptomyces tsukubaensis

labels: bioengineering


sentences: 3D Bioprinted perfusable and vascularized breast tumor model for dynamic screening of chemotherapeutics and CAR-T cells


sentences: Case-control analysis of single-cell RNA-seq studies


sentences: Drug Mechanism Enrichment Analysis: A tool to link molecular signatures with sensitivity to drug mechanisms of action


sentences: EsMeCaTa: Estimating metabolic capabilities from taxonomic affiliations


sentences: Feature selection and aggregation for antibiotic resistance GWAS in Mycobacterium tuberculosis: a comparative study.


sentences: -Labeled PARP-1 PET Imaging of PSMA Targeted Alpha Particle Radiotherapy Response

labels: cancer biology


sentences: Comparison of co-immunoprecipitation techniques for effective identification of SNTA1 interacting proteins in breast cancer cells


sentences: SciCV, the Swiss National Science Foundation's new CV format

labels: scientific communication and education


sentences: Robust group- but limited individual-level (longitudinal) reliability and insights into cross-phases response prediction of conditioned fear


sentences: Resolving the mesoscopic missing link: Biophysical modeling of EEG from cortical columns in primates


sentences: Tuning of motor outputs produced by spinal stimulation during voluntary control of torque directions in monkeys


sentences: High-level visual areas act like domain-general filters with strong selectivity and functional specialization


sentences: Subjectivity of time perception alters choice preference for future rewards through fronto-striatal value signal dynamics


sentences: IRON REGULATORY PROTEIN (IRP)-MEDIATED IRON HOMEOSTASIS IS CRITICAL FOR NEUTROPHIL DEVELOPMENT AND DIFFERENTIATION IN THE BONE MARROW

labels: immunology


sentences: Minicollagens play the governing role in polar capsule formation in parasitic cnidarians, the Myxozoa

labels: developmental biology


sentences: Gut microbiota composition in colorectal cancer patients is genetically regulated


sentences: Cytokine and chemokine profile in patients hospitalized with COVID-19: A comparative study

labels: biochemistry


sentences: Potent and specific human monoclonal antibodies against SARS-CoV-2 Omicron variant by rapid mRNA immunization of humanized mice


sentences: Dynamical Systems Models for Plasma Dilution

labels: biophysics


sentences: Automated neuron tracking inside moving and deforming animals using deep learning and targeted augmentation


sentences: Targeted Anatomical and Functional Identification of Antinociceptive and Pronociceptive Serotonergic Neurons that project to the Superficial Dorsal Horn


sentences: Prime-boost vaccinations with two serologically distinct chimpanzee adenovirus vectors expressing SARS-CoV-2 spike or nucleocapsid tested in a hamster COVID-19 model


sentences: SARS-CoV-2 Omicron potently neutralized by a novel antibody with unique Spike binding properties


sentences: Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains


sentences: Rethinking the role of intraspecific variability in species coexistence

labels: ecology


sentences: Adaptive Magnetic Resonance


sentences: Patch2Self denoising of Diffusion MRI with Self-Supervision and Matrix Sketching


sentences: The cGAS-STING pathway affects vertebral bone but does not promote intervertebral disc cell senescence or degeneration

labels: cell biology


sentences: Instance segmentation of mitochondria in electron microscopy images with a generalist deep learning model.


sentences: Two different phospholipases C, Isc1 and Pgc1, cooperate to regulate mitochondrial function


sentences: Local actuation of organoids by magnetic nanoparticles


sentences: Modelling global mRNA dynamics during Drosophila embryogenesis reveals a relationship between mRNA degradation and P-bodies


sentences: A naturally arising broad and potent CD4-binding site antibody with low somatic mutation


sentences: Reproductive tradeoffs govern sexually dimorphic tubular lysosome induction in C. elegans


sentences: Gene mutations and molecular evolution of the chikungunya virus E1 and E2 from 2014 to 2019


sentences: Per-Pathogen Virulence of HIV-1 subtypes A, C and D


sentences: Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression


sentences: Hiplot: a comprehensive and easy-to-use web service boosting publication-ready biomedical data visualization

labels: bioinformatics


sentences: Loop extrusion driven volume phase transition of entangled chromosomes


sentences: A model for determining the length distribution of actin filaments in cells


sentences: Stability of asymmetric cell division under confinement: A deformable cell model of cytokinesis applied to C. elegans development


sentences: Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome depleted regions


sentences: Interface resistance of biomolecular condensates


sentences: Computational Study of Ion Permeation Through Claudin-4 Paracellular Channels


sentences: Analysis of alternative mRNA splicing in vemuraf-enib-resistant melanoma cells


sentences: A mathematical model of antibiotic resistance gene flow from livestock and spread amongst humans


sentences: Enhanced envelope coding following acoustic trauma is detrimental to neural coding of speech in noise

labels: neuroscience


sentences: Patterns of retrieval-related cortico-striatal connectivity are stable across the adult lifespan


sentences: Development of visual cortex in human neonates are selectively modified by postnatal experience


sentences: High-fidelity dendritic sodium spike generation in human layer 2/3 neocortical pyramidal neurons


sentences: Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating T cells.


sentences: Bidirectional regulation between AP-1 and SUMO genes modulates inflammatory signaling during Salmonella Typhimurium infection

labels: microbiology


sentences: The coordination between penicillin-binding protein 1a (PBP1a) and the hydrolytic peptidase DacB determines the integrity of bacterial cell poles


sentences: Post-transcriptional regulation by copper with a new upstream Open Reading Frame


sentences: Modification of the SUMO activating enzyme subunit SAE2 directs SUMO isoform bias required for mitotic fidelity.

labels: molecular biology


sentences: Pathogen-driven induction of a host transcriptome facilitating epithelial-to-mesenchymal transition


sentences: Maternal H3K36 and H3K27 HMTs protect germline immortality via regulation of the transcription factor LIN-15B


sentences: Rapid colour changes in a tiny threatened gecko do not impede computer-assisted individual recognition


sentences: Distilling complex evolutionary histories with shiftPlot


sentences: Novel Murine models of Mania and Depression

labels: animal behavior and cognition


sentences: Control algorithms underlying the translational optomotor response


sentences: Long-term memory in frog-eating bats


sentences: Prioritized single-cell proteomics reveals molecular and functional polarization across primary macrophages


sentences: Engineering Principles and Algorithmic Design Synthesis for Ultracompact Bio-Hybrid Perfusion Chip


sentences: Proteochemometric method for pIC50 prediction of Flaviviridae


sentences: GPCR-IFP: A Web Server for Analyzing G-Protein Coupled Receptor-Ligand Fingerprint Interaction from Experimental Structures


sentences: Extracting physical characteristics of higher-order chromatin structures from 3D image data


sentences: Hsp multichaperone complex buffers pathologically modified Tau


sentences: Topological action potentials in engineered tissues


sentences: Gene expression signature of castrate resistant prostate cancer


sentences: Extracellular matrix guidance determines proteolytic and non-proteolytic cancer cell patterning


sentences: No evidence of induced skin cancer or other skin abnormalities after long term (66 week) chronic exposure to 222-nm far-UVC radiatio


sentences: Humans trade-off energetic cost with fatigue avoidance while walking

labels: physiology


sentences: Mesembryanthemum crystallinum plasma membrane root aquaporins are regulated via clathrin-coated vesicles in response to salt stress

labels: plant biology


sentences: DUF581-9 (At2g44670; FLZ3) negatively regulates SnRK1 activity by interference with T-loop phosphorylation


sentences: Water influx is required for CD4+ T cell activation and T cell-dependent antibody responses


sentences: Plasma iron controls neutrophil production and function


sentences: DISTINCTIVE FEATURES OF THE RESPIRATORY SYNCYTIAL VIRUS PRIMING LOOP COMPARED TO OTHER NON-SEGMENTED NEGATIVE STRAND RNA VIRUSES


sentences: Genetic and environmental drivers of large-scale epigenetic variation in Thlaspi arvense

labels: evolutionary biology


sentences: Spatial transcriptomics reveal markers of histopathological changes in Duchenne muscular dystrophy mouse models

labels: genomics


sentences: DNA co-methylation has a stable structure and is related to specific aspects of genome regulation


sentences: Technology applications in bovine gait analysis: a scoping review

labels: zoology


sentences: Female reproductive fluid composition differs based on mating system in Peromyscus mice


sentences: Projective LDDMM: Spatially Reconstructing a Story of Rostrally-Dominant Tau in Alzheimer's Disease

labels: bioengineering


sentences: Ubiquitous lognormal distribution of neuron densities across mammalian cerebral cortex


sentences: Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy


sentences: Biocompatible polymers for scalable production of human neural organoids


sentences: Transcriptomic similarity in the mouse and human brain


sentences: Impact of maternal protein restriction on hypoxia-inducible factor (HIF) expression in male fetal kidney development


sentences: A single amino acid transporter controls the uptake of priming-inducing beta-amino acids and the associated trade-off between induced resistance and plant growth.


sentences: Alpha-mannosidase-2 modulates arbovirus infection in a pathogen- and Wolbachia-specific manner in Aedes aegypti mosquitoes


sentences: Establishment of an efficient transformation and CRISPR/Cas9-mediated gene editing system in Chinese local planting cassava (Manihot esculenta Crantz) cultivar SC8


sentences: Combining quadrat, rake and echosounding to estimate submerged aquatic vegetation biomass at the ecosystem scale


sentences: Transcriptomic analysis of the C3-CAM transition in Cistanthe longiscapa, a drought tolerant plant in the Atacama Desert


sentences: Timely sleep coupling: spindle-slow wave synchrony is linked to early amyloid-β burden and predicts memory decline


sentences: Inka2, a novel Pak4 inhibitor, regulates actin dynamics in dendritic spine development


sentences: COVID-19 patients have increased levels of membrane-associated and soluble CD48

labels: immunology


sentences: Pre-exposure to mRNA-LNPs reprograms adaptive and innate immune responses in an inheritable fashion


sentences: Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortex


sentences: Glial control of sphingolipid levels sculpts diurnal remodeling of sleep circuitry


sentences: Synapses in oligodendrocyte precursor cells are dynamic and contribute to Ca2+ activity


sentences: The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton


sentences: Inducible depletion of Scleraxis-lineage cells during tendon healing impairs multi-scale restoration of tendon structure


sentences: Coverage-preserving sparsification of overlap graphs for long-read assembly


sentences: Geology and discovery record of the Trinil Pithecanthropus erectus site, Java

labels: paleontology


sentences: The rate of information transmission through the MAPK/ERKsignaling pathway stimulated in a pulsatile manner

labels: systems biology


sentences: Gene Co-expression Connectivity Predicts Gene Targets Underlying High Ionic Liquid Tolerance in Yarrowia lipolytica


sentences: Diminished distractor filtering with increased perceptual load and sustained effort explains attention deficit in post-stroke fatigue


sentences: The combination of Hebbian and predictive plasticity learns invariant object representations in deep sensory networks


sentences: EXONIZATION BY THE EMERGENCE OF A CLEAVAGE-POLYADENYLATION SITE


sentences: Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1 mediated HSR

labels: genetics


sentences: Plasmid characterization in bacterial isolates of public health relevance in a tertiary healthcare facility in Kilimanjaro, Tanzania


sentences: Towards reliable quantification of cell state velocities


sentences: DENVIS: scalable and high-throughput virtual screening using graph neural networks with atomic and surface protein pocket features


sentences: Complementing machine learning-based structure predictions with native mass spectrometry

labels: biophysics


sentences: MINSTED nanoscopy enters the Angstrom localization range


sentences: Proteomic profiling identifies co-regulated expression of splicing factors as a characteristic feature of intravenous leiomyomatosis

labels: cancer biology


sentences: KAT5 activity regulates G0-like states in human gliomas


sentences: Dietary Induced Dynamic Plasticity of Intestinal Stem Cells and the Mucosa in Elevating Risk for Tumor Development


sentences: Toxicological Analysis of Poly-Lactide Co-Glycolide Microparticles, Chitosan Nanoparticles and Poly(Anhydride) Nanoparticles in Vero Cell

labels: pharmacology and toxicology


sentences: Single-nucleotide substitution determines pollen production in Japanese cedar


sentences: Generalized Method of Moments improves parameter estimation in biochemical signaling models of time-stamped single-cell snapshot data


sentences: Sparse coding models predict a spectral bias in the development of primary visual cortex (V1) receptive fields

labels: neuroscience


sentences: Reproducible Tract Profiles (RTP2): from diffusion MRI acquisition to clinical practice and research


sentences: Altered PVN-to-CA2 hippocampal oxytocin pathway and reduced number of oxytocin-receptor expressing astrocytes in heart failure rats


sentences: A murine model of hnRNPH2-related neurodevelopmental disorder recapitulates clinical features of human disease and reveals a mechanism for genetic compensation of HNRNPH2


sentences: Hyper-adaptation in the Human Brain: Functional and structural changes in the foot section of the primary motor cortex in a top wheelchair racing Paralympian


sentences: Fine oculomotor knowledge enhances high-acuity vision


sentences: Characterizing brain imaging features associated with ADAS-Cog13 sub-scores with 3D convolutional neural networks


sentences: The Cocktail Party Effect in Post-Stroke Fatigue: an EEG study


sentences: pTDP-43 aggregates accumulate in the gut and other non-central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis


sentences: Causal Inference on Neuroimaging Data with Mendelian Randomisation


sentences: A multi-scale fusion CNN model based on adaptive transfer learning for multi-class MI-classification in BCI system


sentences: Beneficial effects of prolonged 2-phenylethyl alcohol inhalation on chronic distress-induced anxio-depressive-like phenotype in female mice


sentences: Condensin positioning at telomeres by Taz1 promotes telomere disjunction in anaphase

labels: cell biology


sentences: Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells


sentences: Towards understanding diversity, endemicity and global change vulnerability of soil fungi

labels: ecology


sentences: A novel PLS1 c.981+1G>A variant causes autosomal-dominant hereditary hearing loss in a family via up-regulation of the PI3K-Akt signaling pathway


sentences: A novel class of long small RNAs associates with Argonaute1 and is up-regulated by nutrient deprivation in the alga Chlamydomonas


sentences: Tissue-adjusted pathway analysis of cancer (TPAC)


sentences: Lack of self-medication by fungus infected Lasius platythorax ants in a multitrophic experiment

labels: animal behavior and cognition


sentences: Characterization of Quantum Dots with Hyperspectral Fluorescence Microscopy for Multiplexed Optical Imaging of Biomolecules


sentences: Fragment-Based Ligand Generation Guided By Geometric Deep Learning On Protein-Ligand Structure


sentences: Bioinformatics Analysis of next generation sequencing data for Risk Prediction in Patients with Type 1 diabetes mellitus

labels: bioinformatics


sentences: Phenotype to genotype mapping using supervised and unsupervised learning


sentences: Modeling of Aryl Hydrocarbon Receptor Pathway Intrinsic Immunometabolic Role using Glioblastoma Stem Cells and Patient-Derived Organoids


sentences: SPDEF promotes the classical subtype of pancreatic ductal adenocarcinoma.


sentences: Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy

labels: pathology


sentences: Temporal integration of rod signals in luminance and chromatic pathways

labels: physiology


sentences: Novel diversity panel facilitates genomic dissection of lodging in tef (Eragrostis tef)

labels: plant biology


sentences: Heterocyclic aromatic amines (HAAs) target mitochondrial physiology


sentences: Emotional intensity can enrich or degrade memories: impact of the amygdalar pathway on hippocampus through inhibitory neurons


sentences: Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals

labels: developmental biology


sentences: Understandable Multifunctionality Measures Using Hill Numbers


sentences: Peripheral and central employment of acid-sensing ion channels during early bilaterian evolution

labels: evolutionary biology


sentences: Standardization of cytological behavior of pollens in sorghum by Image analysis


sentences: Symbolic quantitative cognition in wild zebrafish (Danio rerio)


sentences: Evidence-based calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for clinical use of PP3/BP4 criteria


sentences: Fate mapping melanoma persister cells through regression and into recurrent disease in adult zebrafish


sentences: POU2AF2/C11orf53 functions as a co-activator of POU2F3 by maintaining chromatin accessibility and enhancer activity


sentences: Distribution and frequency of salivary gland tumours: an international multicenter study


sentences: Spatio-temporal modeling reveals a layer of tunable control circuits for the distribution of cytokines in tissues