sentences: A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model


sentences: An engineered ACE2 decoy receptor can be administered by inhalation and potently targets the BA.1 and BA.2 omicron variants of SARS-CoV-2

labels: microbiology


sentences: A Rapid, High Throughput, Viral Infectivity Assay using Automated Brightfield Microscopy with Machine Learning


sentences: Analytic representation of inhomogeneous-resolution maps of three-dimensional scalar fields

labels: molecular biology


sentences: A widely applicable and cost-effective method for general and specific RNA-protein complex isolation


sentences: GLOBAL HOST RESPONSES TO THE MICROBIOTA AT SINGLE CELL RESOLUTION IN GNOTOBIOTIC ZEBRAFISH

labels: developmental biology


sentences: Dysregulated H19/Igf2 expression disrupts cardiac-placental axis during development of Silver Russell Syndrome-like mouse models


sentences: Finding the strongest gene drive: Simulations reveal unexpected performance differences between Anopheles homing suppression drive candidates

labels: genetics


sentences: Identification of consensus hairpin loop structure among the negative sense sub-genomic RNAs of SARS-CoV-2

labels: bioinformatics


sentences: Unique molecular signatures sustained in circulating monocytes and regulatory T cells in Convalescent COVID-19 patients

labels: immunology


sentences: Cells with Stochastically Increased Methyltransferase to Restriction Endonuclease Ratio Provide an Entry for Bacteriophage into Protected Cell Population


sentences: Mosaic RBD nanoparticles protect against multiple sarbecovirus challenges in animal models


sentences: High resolution parallel sequencing reveals multi-strain Campylobacter in broiler chicken flocks testing 'negative' by conventional culture methods: implications for control of Campylobacter infection.


sentences: miR-34a negatively regulates cell cycle factor Cdt2/DTL in HPV infected Cervical Cancer Cells


sentences: Deep selection shapes the intragenomic diversity of rRNA genes

labels: genomics


sentences: Mitigating the Bfl-1-mediated antiapoptotic pathway in diffuse large B cell lymphoma by inhibiting HDACs

labels: cancer biology


sentences: Molecular basis of uracil/H+ symport mechanism operated by the FurE/NCS1 transporter


sentences: Monitoring of urban ecological environment including air quality using satellite imagery

labels: ecology


sentences: Systemic ablation of Camkk2 impairs metastatic colonization and improves insulin sensitivity in TRAMP mice: Evidence for cancer cell-extrinsic CAMKK2 functions in prostate cancer


sentences: Safety assessment of insecticidal proteins: A case study utilizing His-tagged protein to determine the safety of Mpp75Aa1.1, a new ETX_MTX2 protein that controls western corn rootworm

labels: pharmacology and toxicology


sentences: Rhythmic modulation of prediction errors: a possible role for the beta-range in speech processing

labels: neuroscience


sentences: Serotonin Modulates an Inhibitory Input to the Central Amygdala from the Ventral Periaqueductal Gray


sentences: Cortical integration of higher-order thalamic inputs is lineage-dependent


sentences: Mapping the subcortical connectome using in vivo diffusion MRI: feasability and reliability


sentences: Action sequence dynamics rely on accessory hyperdirect pathway-related targets in the striatum


sentences: A multiplexed in vivo approach to identify driver genes in small cell lung cancer


sentences: Improving the Safety of Cultured Meat Using Basal Medium Prepared using Food Ingredients

labels: cell biology


sentences: ALS-associated mutant KIF5A forms oligomers and aggregates and induces neuronal toxicity


sentences: The force required to remove tubulin from the microtubule lattice

labels: biophysics


sentences: Autophagy-cell death balance is maintained by Polycomb-mediated regulation during stem cell differentiation


sentences: Identification of a novel chalcone reductase gene for isoliquiritigenin biosynthesis in dahlia (Dahlia variabilis)

labels: plant biology


sentences: Stability and learning in excitatory synapses by nonlinear inhibitory plasticity


sentences: LTD-inducing low frequency stimulation enhances p-Tau181 and p-Tau217 in an age-dependent manner in live rats


sentences: Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus


sentences: Zebrafish cornea formation and homeostasis reflect robustness in camera-type eye biology, regardless of its environment


sentences: Wild common crossbills produce redder body feathers when their wings are clipped

labels: evolutionary biology


sentences: Social Learning of a Spatial Task by Observation Alone

labels: animal behavior and cognition


sentences: ggtranscript: an R package for the visualization and interpretation of transcript isoforms using ggplot2


sentences: Sorting of plant mitochondrial and plastid heteroplasmy is extremely rapid and depends on MSH1 activity


sentences: Glutathione-mediated plant response to high-temperature


sentences: Noise facilitates entrainment of a population of uncoupled limit cycle oscillators

labels: systems biology


sentences: Deciphering the fibre-orientation independent component of R2* (R2,iso*) in the human brain with a single multi-echo gradient-recalled-echo measurement under varying microstructural conditions


sentences: Age-related differences in functional network segregation in the context of sex and reproductive stage


sentences: Context-independent expression of spatial code in hippocampus


sentences: STEPS 4.0: Fast and memory-efficient molecular simulations of neurons at the nanoscale


sentences: NDR1/2 kinases regulate membrane trafficking, enable efficient autophagy and prevent neurodegeneration


sentences: Excitatory-Inhibitory Recurrent Dynamics Produce Robust Visual Grids and Stable Attractors


sentences: Zfp503/Nlz2 is Required for RPE Differentiation and Optic Fissure Closure


sentences: Molecular characterization of cell types in the squid Loligo vulgaris


sentences: Effects of haemosporidian co-infection and parasitemia on reproductive strategies in a polymorphic species


sentences: High Quality Phasing Using Linked-Read Whole Genome Sequencing of Patient Cohorts Informs Genetic Understanding of Complex Traits


sentences: Genome sequence of 12 Vigna species as a knowledge base of stress tolerance and resistance


sentences: Pangenomics provides insights into the role of synanthropy in barn swallow evolution


sentences: Telomere-to-telomere human DNA replication timing profiles


sentences: Resistance of mitochondrial DNA to chemical-induced germline mutations is independent of mitophagy in C. elegans


sentences: vcferr: Development, Validation, and Application of a SNP Genotyping Error Simulation Framework


sentences: Growth instabilities shape morphology and genetic diversity of cellular aggregates


sentences: Learning of probabilistic punishment as a model of anxiety produces changes in action but not punishment encoding in the dmPFC and VTA


sentences: Primate dopamine neurons activated in rewarding environment by tonic disinhibition from amygdala


sentences: Glial dysregulation in human brain in Fragile X-related disorders


sentences: High-resolution epigenetic profiling identifies novel regulators of COPD in human lung fibroblasts


sentences: The hidden intricacies of aquaporins: Remarkable details in a common structural scaffold


sentences: A novel cis-element enabled bacterial uptake by plant cells


sentences: Genotype by microbiome interactions have large effects on growth in Lotus japonicus


sentences: Classification of Movement-Related Oscillations in sEEG Recordings with Machine Learning


sentences: Health hazards posed by ionizing radiation to human space missions and newly developing methodologies to investigate them


sentences: Inflammaging in human photoexposed skin: Early onset of senescence and imbalanced epidermal homeostasis across the decades.


sentences: Transcriptional control of nucleus accumbens neuronal excitability by Retinoid X Receptor Alpha tunes sensitivity to drug rewards


sentences: Local translation provides the asymmetric distribution of CaMKII required for associative memory formation


sentences: Activation of the CA2-vCA1 pathway reverses social discrimination dysfunction in Shank3B knockout mice


sentences: Sparcl1/Hevin drives inflammatory and neuropathic pain through astrocyte and NMDA receptor signaling


sentences: Large-Scale Benchmarking of Diverse Artificial Vision Models in Prediction of 7T Human Neuroimaging Data


sentences: Individual differences in late positive potential amplitude and theta power predict cue-induced eating


sentences: Lassa virus glycoprotein nanoparticles elicit a neutralizing antibody that defines a new site of vulnerability


sentences: Detection of interphylum transfers of the magnetosome gene cluster in magnetotactic bacteria

labels: microbiology


sentences: Hyperbolic Geometry-Based Deep Learning Methods to Produce Population Trees from Genotype Data


sentences: Model-free Prediction Test with Application to Genomics Data


sentences: CoCoA: Conditional Correlation Models with Association Size


sentences: Multimodal microscale mechanical mapping of cancer cells in complex microenvironments


sentences: Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics


sentences: Natural variation identifies new effectors of water use efficiency in Arabidopsis.


sentences: Profiling the diversity of agonist-selective effects on the proximal proteome environment of G protein-coupled receptors


sentences: The pre-Bötzinger complex is necessary for the expression of post-inspiration


sentences: Post-activation depression produces extensor H-reflex suppression following flexor afferent conditioning


sentences: PAF1 modulates innate immunity by both activation and repression of gene expression.

labels: molecular biology


sentences: Digitizing the coral reef: machine learning of underwater spectral images enables dense taxonomic mapping of benthic habitats


sentences: Molecular basis of DNA recognition by the HMG-box-C1 module of Capicua

labels: biochemistry


sentences: The Modular μSiM Reconfigured: Integration of Microfluidic Capabilities to Study in vitro Barrier Tissue Models under Flow

labels: bioengineering


sentences: An environmentally ultrasensitive fluorine-19 NMR probe for monitoring protein conformational equilibria


sentences: Containing Cancer with Personalized Minimum Effective Dose


sentences: Effect of TSS on anti-CVB3 through TLR3 pathway


sentences: Mutated Tumor Suppressors Follow Oncogenes Profile by the Gene Hypermethylation of Partners in the Protein Interaction Networks


sentences: Single Cell Profiling of CD45+ Spinal Cord Cells Reveals Microglial and B Cell Heterogeneity and Crosstalk Following Spinal Cord Injury


sentences: Cell type profiling in salamanders identifies innovations in vertebrate forebrain evolution


sentences: Slc9a6 mutation causes Purkinje cell loss and ataxia in the spontaneous shaker rat


sentences: An atypical ABC transporter is involved in antifungal resistance and host interactions in the pathogenic fungus Cryptococcus neoformans


sentences: The connection between the gut mycobiome community of natural black soldier fly populations and their environment


sentences: Microtubule-Connexin-43 regulation suppresses arrhythmias and fibrosis in Duchenne muscular dystrophy mice.


sentences: Canonical Wnt Signaling and the Regulation of Divergent Mesenchymal Fgf8 expression in Axolotl Limb Development and Regeneration

labels: developmental biology


sentences: 2-deoxyglucose inhibits yeast AMPK signaling and triggers glucose transporter endocytosis, potentiating the drug toxicity

labels: genetics


sentences: A DEAD-box helicase drives the partitioning of a pro-differentiation NAB protein into nuclear foci


sentences: The Modular μSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro


sentences: Reference-based cell type matching of spatial transcriptomics data

labels: bioinformatics


sentences: The Codon Statistics Database: a Database of Codon Usage Bias


sentences: Fast model-free standardization and integration of single-cell transcriptomics data


sentences: Hip osteoarthritis: A novel network analysis of subchondral trabecular bone structures


sentences: Paclitaxel-loaded PEGylated Cationic Lipid Nanodiscs and Small Liposomes with Protruding Brush Conformation PEG-chains Show Tumor Penetration and Proapoptotic Caspase-3 Activation


sentences: Cell-free prototyping enables implementation of optimized reverse beta-oxidation pathways in heterotrophic and autotrophic bacteria

labels: synthetic biology


sentences: Validation of DeepLabCut as a tool for markerless 3D pose estimation


sentences: Molecular Control of Circuit Plasticity and the Permanence of Imprinted Odor Memory


sentences: Made together, replayed together: Context reinstatement during sleep guides memory consolidation


sentences: Comprehensive profiling of antibody responses to the human anellome using programmable phage display

labels: immunology


sentences: Costimulation of TLR8 responses by CXCL4 in Human Monocytes Mediated by TBK1-IRF5 Signaling and Epigenomic Remodeling


sentences: Reproducible and sensitive micro-tissue RNA-sequencing from formalin-fixed paraffin-embedded tissue for spatial gene expression analysis


sentences: Estimating interaction matrices from performance data for diverse systems

labels: ecology


sentences: Automated identification and registration of anatomical landmarks in C. elegans


sentences: Solvation Dynamics of a Single Triglyceride as a Function of its Chain Length


sentences: Spatial transcriptomic analysis of childhood ependymoma implicates unresolved wound healing as a driver of tumor progression

labels: cancer biology


sentences: 3'UTR-directed, kinase proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells


sentences: A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants


sentences: Vomocytosis of Cryptococcus neoformans cells from murine, bone marrow-derived dendritic cells


sentences: The impact of the rice production system (irrigated vs lowland) on root-associated microbiome from farmer's fields in western Burkina Faso


sentences: Nectar compounds impact bacterial and fungal growth and shift community dynamics in a nectar analog


sentences: Superfast Evolution of Multi-drug Antibiotic Resistance


sentences: The outer mitochondrial membrane protein TMEM11 is a novel negative regulator of BNIP3/BNIP3L-dependent receptor-mediated mitophagy

labels: cell biology


sentences: Discovery of a druggable copper-signaling pathway that drives cell plasticity and inflammation


sentences: Subcellular mapping of the protein landscape of SARS-CoV-2 infected cells for target-centric drug repurposing


sentences: A multidisciplinary analysis of the as-isolated Escherichia coli SufBC2D complex reveals the presence of two new iron-sulfur clusters


sentences: Predicting Protein Function and Orientation on a Gold Nanoparticle Surface Using a Residue-Based Affinity Scale

labels: biophysics


sentences: Reactive oxygen species generated by infrared laser light in optical tweezers inhibits the germination of bacterial spores


sentences: Inositol hexakisphosphate (IP6) accelerates immature HIV-1 Gag protein assembly towards kinetically-trapped morphologies


sentences: Base editing screens map mutations affecting IFNγ signalling in cancer


sentences: spongEffects: ceRNA modules offer patient-specific insights into the miRNA regulatory landscape


sentences: Glia-neuron coupling via a bipartite sialylation pathway promotes neural transmission and stress tolerance in Drosophila

labels: neuroscience


sentences: Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex


sentences: Convergent epitope specificities, V gene usage and public clones elicited by primary exposure to SARS-CoV-2 variants


sentences: Phylogenetic analysis of the origin and spread of plague in Madagascar


sentences: Characterization of the growth and morphology of a BSL-2 Coccidioides posadasii strain that persists in the parasitic life cycle at ambient CO2.


sentences: PinR as a Stress Inducible Inhibitory Transcription Factor in Stopping Stress-induced Mutagenesis Bacterial Evolution of Antibiotic Resistance


sentences: Tuberculosis treatment failure associated with evolution of antibiotic resilience


sentences: DNA methylation in human gastric epithelial cells allows cell type-related plasticity and defines regional identity


sentences: Regulation of EBNA1 Protein Stability by PLOD1 Lysine Hydroxylase


sentences: Structural basis of actin filament assembly and aging


sentences: Driving Forces underlying Selectivity Filter Gating in the MthK Potassium Channel


sentences: Repeated ethanol exposure and withdrawal alters ACE2 expression in discrete brain regions: Implications for SARS-CoV-2 infection


sentences: CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses


sentences: ZccE is a Novel P-type ATPase That Protects Streptococcus mutans Against Zinc Intoxication


sentences: Dynamic de novo adipose tissue development during metamorphosis in Drosophila melanogaster


sentences: The addition of antibiotics to embryo culture media caused altered expression of genes in pathways governing DNA integrity in mouse blastocysts


sentences: Lack of universal mutational biases in a fungal phylum

labels: evolutionary biology


sentences: THRONCAT: Efficient metabolic labeling of newly synthesized proteins using a bioorthogonal threonine analog


sentences: Evolution of decreased aggression in honey bees targeted brain cell gene regulatory networks

labels: genomics


sentences: TOR acts as metabolic gatekeeper for auxin-dependent lateral root initiation in Arabidopsis thaliana

labels: plant biology


sentences: Xanthomonas infection transforms the apoplast into an accessible and habitable niche for Salmonella enterica

labels: microbiology


sentences: Lifting the ban on nuclear import activates Gdown1-mediated modulation of global transcription and facilitates adaptation to cellular stresses


sentences: PPAR-γ activation promotes xenogenic bioroot regeneration by attenuating the xenograft induced-oxidative stress


sentences: Mechano-redox control of Mac-1 de-adhesion from ICAM-1 by protein disulfide isomerase promotes directional movement of neutrophils under flow


sentences: Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets

labels: pharmacology and toxicology


sentences: Membrane compartmentalization of Ect2/Cyk4/Mklp1 and NuMA/dynein/dynactin is essential for cleavage furrow formation during anaphase


sentences: Accounting for cis-regulatory constraint prioritizes genes likely to affect species-specific traits


sentences: Right Anterior Theta Connectivity Predicts Autistic Social Traits in Neurotypical Children


sentences: Neuroimaging within the Dominantly Inherited Alzheimer's Network (DIAN): PET and MRI


sentences: Lagrangian Formalism in Biology: I. Standard Lagrangians and their Role in Population Dynamics


sentences: Quantifying the capacity for assisted migration to achieve conservation and forestry goals under climate change


sentences: Genomic demography of world's ethnic groups and their genomic identity between two individuals


sentences: Development of a new 3D tracking system for multiple marmosets under free-moving conditions

labels: animal behavior and cognition


sentences: DTSyn: a dual-transformer-based neural network to predict synergistic drug combinations


sentences: Pain as a Trigger for Epigenetic Modifications in Limbic Circuitry


sentences: Patient-derived recombinant autoantibodies reveal the subcellular neuroglial distribution and heterogeneous interactome of leucine-rich glioma-inactivated 1


sentences: Focal Non-invasive Deep-brain Stimulation with Temporal Interference for the Suppression of Epileptic Biomarkers


sentences: Sleep spindles favor emotion regulation over memory consolidation of stressors in PTSD


sentences: Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings


sentences: The human placenta dictates the phenotype of decidual macrophages.


sentences: A machine learning method for estimating the probability of presence using presence-background data


sentences: Sex differences in allometry for phenotypic traits indicate that females are not scaled males


sentences: High-density mapping of QTL controlling agronomically important traits in quinoa (Chenopodium quinoa Willd.)


sentences: Acoustic signatures in cavefish populations inhabiting different caves


sentences: The growth rate of DNA condensate droplets increases with the size of participating subunits

labels: bioengineering


sentences: Boquila: NGS read simulator to eliminate read nucleotide bias in sequence analysis


sentences: Transcriptional dynamics of colorectal cancer risk associated variation at 11q23.1 are correlated with tuft cell abundance and marker expression in silico


sentences: Imputation of Low-density Marker Chip Data in Plant Breeding: Evaluation of Methods Based on Sugar Beet


sentences: Optimal inference of molecular interactions in live FRET imaging


sentences: Effects of taurine in mice and zebrafish behavioral assays with translational relevance to schizophrenia


sentences: Toward a first principles understanding of the activation and deactivation mechanisms of class A G-protein coupled receptors and voltage-gated cation channels


sentences: Enhanced performance in perceptual decision making task without deprivation in mice using medial forebrain bundle stimulation


sentences: Large scale in vivo acquisition, segmentation and 3D reconstruction of cortical vasculature using functional ultrasound imaging.


sentences: Reanalysis of double EphA3 knockin maps in mouse shows the importance of chemoaffinity in topographic map formation


sentences: Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease


sentences: Correlative SIP-FISH-SEM-Raman-NanoSIMS links identity, morphology, biochemistry, and physiology of environmental microbes


sentences: Acinetobacter baumannii sampled from cattle and pigs represent novel clones


sentences: Transcriptomics, Regulatory Syntax, and Enhancer Identification in Heterogenous Populations of Mesoderm-Induced ESCs at Single-Cell Resolution

labels: developmental biology


sentences: Generation of raptor diversity in Europe: linking speciation to climate changes and the ability to migrate


sentences: Do amplifiers of selection maximise average fitness?


sentences: Phylogenomics Illuminates the Evolutionary History of Wild Silkmoths in Space and Time (Lepidoptera: Saturniidae)


sentences: Mesoscopic oblique plane microscopy (Meso-OPM) - enabling large-scale 4D isotropic cellular resolution imaging with a diffractive light sheet


sentences: scAllele: a versatile tool for the detection and analysis of variants in scRNA-seq


sentences: MultiHeadGAN: A Deep Learning Method for Low Contrast Retinal Pigment Epithelium Cells Segmentation in Fluorescent Flatmount Microscopy Images


sentences: A Quantitative Modelling Approach for DNA Repair on a Population Scale


sentences: A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage


sentences: The sugarless grape trait characterized by single berry phenotyping


sentences: Memory reactivation in slow wave sleep enhances relational learning


sentences: Multi-Layered Maps of Neuropil with Segmentation-Guided Contrastive Learning


sentences: A comparison of intracranial volume estimation methods and their cross-sectional and longitudinal associations with age


sentences: Population genetic analysis reveals the role of natural selection and phylogeography on genome-wide diversity in an extremely compact and reduced microsporidian genome


sentences: Holobiont transcriptomes for the critically endangered staghorn coral (Acropora cervicornis) from two environmentally distinct sites on Turneffe Atoll, Belize


sentences: Effects of low intensity pulsed ultrasound stimulation on metabolic lipolysis of adipocytes


sentences: Protein language models trained on multiple sequence alignments learn phylogenetic relationships


sentences: A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer


sentences: Establishing combination PAC-1 and TRAIL regimens for treating ovarian cancer based on patient-specific pharmacokinetic profiles using in silico clinical trails


sentences: Measurement of plant water status via static uniaxial compression of the leaf lamina


sentences: The origin of diffuse noxious inhibitory controls


sentences: Novel Adult Cortical Neuron Processing and Screening method illustrates Sex- and Age-dependent effects of pharmaceutical compounds


sentences: Different astrocyte-to-neuron conversion tracing reporters affect results in mouse striatum under Ptbp1 knockdown


sentences: Bacteriophages antagonize cGAS-like immunity in bacteria


sentences: NtrC expression at lag-phase improves competitive fitness under low and fluctuating nutrient condition


sentences: Multiethnic Polygenic Risk Prediction in Diverse Populations through Transfer Learning

labels: genetics


sentences: GTAGMe-seq: joint profiling of genetic variants, DNA methylation, GpC methyltransferase footprints, and 3D genome in the same DNA molecules


sentences: On the Geometry of Interacting Axon Tracts in Relation to Their Functional Properties


sentences: ACE2 engagement exposes the fusion peptide to pan-coronavirus neutralizing antibodies


sentences: The Structural and Biochemical Basis for FER Receptor Kinase Early Signaling Initiation in Arabidopsis

labels: biochemistry


sentences: Sabatier principle for rationalizing enzymatic hydrolysis of a synthetic polyester


sentences: Endothelial Caspase-9 Promotes Glial Changes, Inflammation, and Contrast Sensitivity Decline in Retinal Vascular Injury


sentences: Homozygous CADPS2 mutations cause neurodegenerative disease with Lewy bodies in parrots


sentences: Selective IL13Rα2-Targeted Functionality of IL13-Ligand CARs is Enhanced by Inclusion of 4-1BB Co-Stimulation


sentences: SARS-CoV-2 accessory protein ORF8 decreases antibody-dependent cellular cytotoxicity


sentences: Improved fluorescent Listeria spp. biosensors for analysis of antimicrobials by flow cytometry


sentences: CRISPRi screen for enhancing heterologous α-amylase yield in Bacillus subtilis


sentences: Orphan nuclear receptors promote alternative lengthening of telomeres (ALT) through ALT-associated PML bodies

labels: molecular biology


sentences: Structural insights into crista junction formation by the Mic60-Mic19 complex


sentences: In vitro reconstitution of calcium-dependent recruitment of the human ESCRT machinery in lysosomal membrane repair


sentences: A partnership of the lipid scramblase XK and of the lipid transfer protein VPS13A at the plasma membrane


sentences: Evolution of CRISPR-associated Endonucleases as Inferred from Resurrected Proteins


sentences: Characterizing Photosynthetic Biofuel Production: Isotopically non-stationary 13C metabolic flux analysis (INST-13CMFA) on limonene producingSynechococcus sp. PCC 7002


sentences: Differential gene expression profiling reveals potential biomarkers and pharmacological compounds against SARS-CoV-2: insights from machine learning and bioinformatics approaches

labels: bioinformatics


sentences: Predicting variability in nascent RNA from transcription initiation kinetics


sentences: Comparative Structural and Dynamics Study of Free and gRNA-bound FnCas9 and SpCas9 Proteins


sentences: Intracellular Aβ42 aggregation leads to cellular thermogenesis


sentences: Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival


sentences: WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation


sentences: PRMT5 is a therapeutic target in choroidal neovascularization


sentences: Interfering with plant developmental timing promotes susceptibility to insect vectors of a bacterial parasite


sentences: HTL/KAI2 signalling substitutes for light to control plant germination


sentences: A mini-TGA protein, lacking a functional DNA-binding domain, modulates gene expression through heterogeneous association with transcription factors


sentences: Proteomic characterization of spinal cord synaptoneurosomes from Tg-SOD1/G93A mice supports a role for MNK1 and local translation in the early stages of amyotrophic lateral sclerosis


sentences: TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8+ T cells

labels: immunology


sentences: Controlling taxa abundance improves metatranscriptomics differential analysis


sentences: Obligate sexual reproduction of a homothallic fungus closely related to the Cryptococcus pathogenic species complex


sentences: Emerging Roles of Importin alpha/beta and EB1 in Differential Regulation of Kif18B Astral Microtubule Destabilization


sentences: A conserved PLK1 docking site in TopBP1 maintains genome integrity during mitosis


sentences: Species Distribution Modeling of Aedes aegypti in Maricopa County, Arizona from 2014-2020

labels: ecology


sentences: Genetic surveillance of SARS-CoV-2 Mpro reveals high sequence and structural conservation prior to the introduction of protease inhibitor Paxlovid


sentences: Mechanism and consequence of daily modulation of cortical parvalbumin-positive inhibitory neurons


sentences: Convergent impact of schizophrenia risk genes


sentences: Longer metaphase and fewer chromosome segregation errors in modern human than Neandertal brain development


sentences: Inhibiting presynaptic calcium channel mobility in the auditory cortex suppresses synchronized input processing


sentences: Glucocorticoids Mediate Transcriptome-wide Alternative Polyadenylation: Mechanisms and Functional Implications


sentences: Jumping out of trouble: Evidence for a cognitive map in guppies (Poecilia reticulata)


sentences: 3D Organic Bioelectronics for Monitoring In Vitro Stem Cell Cultures


sentences: Transcriptome of the coralline alga Calliarthron tuberculosum (Corallinales, Rhodophyta) reveals convergent evolution of a partial lignin biosynthesis pathway


sentences: Human Digital Twin: Automated Cell Type Distance Computation and 3D Atlas Construction in Multiplexed Skin Biopsies

labels: cell biology


sentences: Nitrite lowers the oxygen cost of ATP supply in skeletal muscle cells by stimulating the rate of glycolytic ATP synthesis


sentences: Cellular compartmentalisation and receptor promiscuity as a strategy for accurate and robust inference of position during morphogenesis

labels: biophysics


sentences: Liquid droplet aging and fibril formation of the stress granule protein TIA1 low complexity domain


sentences: Behavioral and imaging analysis of Foxg1 heterozygous mice

labels: neuroscience


sentences: S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress


sentences: Constitutive, calcium-independent endoplasmic reticulum-plasma membrane contact site oscillations and its implications in store-operated calcium entry


sentences: Ancestral origins are associated with SARS-CoV-2 susceptibility and protection in a Florida patient population


sentences: High-throughput imaging and quantitative analysis uncovers the nature of plasmid positioning by ParABS


sentences: Prediction of gene essentiality using machine learning and genome-scale metabolic models

labels: systems biology


sentences: Evaluation of the broth microdilution methodology for susceptibility testing of Mycobacterium tuberculosis in Peru


sentences: Influenza A virus RNA Polymerase targets the chromatin of innate immune response genes


sentences: Plastomes of Hyalomonas oviformis and Hyalogonium fusiforme evolved dissimilar architecture after loss of photosynthesis

labels: genomics


sentences: WWP2 osteoarthritis risk allele rs1052429-A confers risk by affecting cartilage matrix deposition via hypoxia associated genes


sentences: High fat diet initiates rapid adaptation of the intestine


sentences: Microtubules self-repair in living cells


sentences: TYMV has dual action on the plant RNA silencing defense through its VSR P69 and the host RNASE THREE LIKE1

labels: plant biology


sentences: Structure-function conservation between the methyltransferases SETD3 and SETD6


sentences: Computational rewiring of allosteric pathways reprograms GPCR selective responses to ligands


sentences: Ageing critically transforms the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it


sentences: Effects of organic fertilizer digestate on the growth of tomato (Lycopersicon esculentum Mill)


sentences: Neighbouring modifications interfere with the detection of phosphorylated alpha-synuclein at Serine 129: Revisiting the specificity of pS129 antibodies


sentences: Identification and characterization of the T cell receptor (TCR) repertoire of the Cynomolgus macaque (Macaca Fascicularis)


sentences: Resolution of glycogen and glycogen-degrading activities reveals correlates of Lactobacillus crispatus dominance in a cohort of young African women

labels: microbiology


sentences: Hypoxia-induced tracheal elasticity in vector beetle facilitates the loading of pinewood nematode


sentences: The Role of Replication-induced Chromosomal Copy Numbers in Spatio-temporal Gene Regulation and Evolutionary Chromosome Plasticity


sentences: A divide-and-conquer approach for genomic prediction in rubber tree using machine learning


sentences: Correlation and Path Coefficient Analyses in Hot Pepper (Capsicum annum L.)


sentences: CUT&Tag recovers up to half of ENCODE ChIP-seq peaks


sentences: Gradient-k: Improving the performance of K-Means using the density gradient


sentences: Deep learning to decompose macromolecules into independent Markovian domains


sentences: Painters in chromatin: a unified quantitative framework to systematically characterize epigenome regulation and memory


sentences: In silico analysis of Bacopa monnieri (L.) Wettst. compounds for drug development against Neurodegenerative Disorders

labels: pharmacology and toxicology


sentences: Hypercaloric diet triggers transient molecular rearrangements of astrocytes selectively in the arcuate nucleus


sentences: Fear memory in humans is consolidated over time independent of sleep


sentences: Incertohypothalamic A13 dopaminergic neurons are involved in fine forelimb movements but not reward


sentences: Plant-invertebrate interactions across a forested retrogressive chronosequence


sentences: Performance and limitations of linkage-disequilibrium-basedmethods for inferring the genomic landscape of recombination anddetecting hotspots: a simulation study


sentences: Variable Selection via Grace-AKO with Applications in Genomics


sentences: Contributions of the N-terminal intrinsically disordered region of the SARS-CoV-2 nucleocapsid protein to RNA-induced phase separation


sentences: The dynamical Matryoshka model: 2. Modeling of local lipid dynamics at the sub-nanosecond timescale in phospholipid membranes


sentences: Mapping whole-brain projections of anatomically defined prefrontal neurons using combined 3D convolution networks


sentences: Hierarchical architecture of dopaminergic circuits enables second-order conditioning in Drosophila


sentences: Fear extinction is regulated by long noncoding RNA activity at the synapse


sentences: Screening the Pathogen Box Compounds for Activity Against Plasmodium falciparum Sporozoite Motility


sentences: Conformational flexibility, lipid binding, and regulatory domains in CelTOS


sentences: Cross neutralization of Omicron BA.1 against BA.2 and BA.3 SARS-CoV-2


sentences: Brequinar and Dipyridamole in Combination Exhibits Synergistic Antiviral Activity Against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19


sentences: Methylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2Omicron variant BA.1 infection of human airway epithelial explant cultures


sentences: Identification of C270 as a novel site for allosteric modulators of SARS-CoV-2 papain-like protease


sentences: An in situ cut-and-paste genome editing platform mediated by CRISPR/Cas9 or Cas12a


sentences: Clinical mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2


sentences: Protein Quaternary Structures in Solution are a Mixture of Multiple forms


sentences: Helical remodeling augments 5-lipoxygenase activity


sentences: Sensitive detection and structural characterisation of UV-induced cross-links in protein-RNA complexes using CLIR-MS


sentences: Prediction of infectivity of SARS-CoV2: Mathematical Model with Docking Simulation analysis between Spike Protein and ACE2


sentences: Model guided design of enhanced bi-stable controllers to effectively switch cellular states

labels: synthetic biology


sentences: CIS calibrates GM-CSF signalling strength to regulate macrophage polarization via a STAT5-IRF8 axis


sentences: cGASylation by a bacterial E1-E2 fusion protein primes antiviral immune signaling


sentences: SARS-CoV-2 Omicron is specifically restricted in its replication in human lung tissue, compared to other variants of concern


sentences: On the relationship between Pathogenic Potential and Infective Inoculum


sentences: Vaccination decreases the risk of influenza A virus reassortment with a concomitant increase in subgenomic genetic variation in pigs


sentences: Small Molecules Restore Azole Activity Against Drug-Tolerant and Drug-Resistant Candida Isolates


sentences: Ultra-deep Sequencing of Hadza Hunter-Gatherers Recovers Vanishing Microbes


sentences: Chaperone Requirements for De Novo Folding of Saccharomyces cerevisiae Septins


sentences: Chemokine Receptor 1 and its associated immune pathway are downregulated in SF3B1MT blood and non-blood cancers


sentences: Monitoring promoter activity by RNA editing based reporter


sentences: Impact of hydrostatic pressure on organic carbon cycling of the deep-sea microbiome


sentences: Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species

labels: evolutionary biology


sentences: Competition for H2A.Z between genes and repetitive elements establishes response to anti-viral immune activation


sentences: A chromosome-length assembly of the Hawaiian Monk seal (Neomonarchus schauinslandi) confirms genomic stability in the Pinnipeds and a prolonged history of "genetic purging"


sentences: Evaluating Client Protein Recovery by the Hsp40s DNAJB8 and DNAJB1 with AP-MS


sentences: A metabolic labeling-based chemoproteomic platform unravels the physiological roles of choline metabolites


sentences: Structural interplay between DNA-shape proteinrecognition and supercoiling: the case of IHF


sentences: Oncogene-induced matrix reorganization controls CD8+ T cell function in the tumor microenvironment

labels: cancer biology


sentences: Protein Kinase C Delta Regulates Mononuclear Phagocytes and Hinders Response to Immunotherapy in Cancer


sentences: Sialophorin is an essential host element for vaccine immunity against pulmonary fungal infections


sentences: A ROS-dependent mechanism to drive progression through S phase


sentences: Understanding the transcriptional response to ER stress in Chinese hamster ovary cells using multiplexed single cell RNA-seq


sentences: AMPK-p38 axis converts human pluripotent stem cells to naïve state


sentences: Early Endosome Capture Proteomics and its Application to Amyloid Precursor Protein Intramembrane Processing by β and γ-Secretases


sentences: The molecular organization of flat and curved caveolae indicates bendable structural units at the plasma membrane.


sentences: MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size

labels: genetics


sentences: Prioritization of driver genes in cancer-associated copy number alterations identifies B4GALT5 as a glycooncogene


sentences: Timing Is Everything In Autumn - Coordination Of Senescence Onset By A Transcriptional Program In Response To Environmental And Phytohormone Signals


sentences: Prostaglandin D2 pathway in a transgenic rat model of Alzheimer's disease: therapeutic potential of timapiprant a DP2 antagonist


sentences: Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury


sentences: Protons in gating the Kv1,2 channel: a calculated conformational change in response to addition of a proton, and a proposed path from voltage sensing domain to gate


sentences: PIEZO1-dependent erythrocyte dehydration as the mechanism for selection of an allele protecting from severe malaria.


sentences: mEos4b photoconversion efficiency depends on laser illumination conditions used in PALM


sentences: One-sided design of protein-protein interaction motifs using deep learning


sentences: Computational design of ultrasensitive flexible peptide:receptor signaling complexes for enhanced chemotaxis


sentences: High temperature molecular motions within a model protomembrane architecture


sentences: Hand-foot coordination is significantly influenced by motion direction in individuals with autism spectrum disorder


sentences: A neuromodulatory model for determining the effect of emotion-respiration-cognition coupling on the time-to-respond


sentences: Electrophysiological signatures reveal spinal learning mechanisms for a lasting sensorimotor adaptation


sentences: Excitatory and inhibitory effects of HCN channel modulation on excitability of layer V pyramidal cells


sentences: A recurrent network architecture explains tectal activity dynamics and experience-dependent behaviour


sentences: Computational analysis of memory consolidation following inhibitory avoidance (IA) training in adult and infant rats: critical roles of CaMKIIα and MeCP2


sentences: High-contrast en-bloc staining of mouse whole-brain samples for EM-based connectomics


sentences: Unraveling axonal mechanisms of traumatic brain injury


sentences: Integrated single-cell (phospho-)protein and RNA detection uncovers phenotypic characteristics of human antibody secreting cells.


sentences: Evaluating impact of experimental design on accuracy of parameter estimation and model selection efficiency: T cell clustering as a case study


sentences: The cardiopharyngeal mesoderm contributes to lymphatic vessel development

labels: developmental biology


sentences: Lethal and sub-lethal concentrations of pesticides detected in milkweeds purchased from nurseries across the United States


sentences: The interplay between habitat fragmentation and life traits affects specialization in lichen symbioses


sentences: Introduced crops supplement rather than replace indigenous crops in an African center of agrobiodiversity


sentences: Climate adaptation and vulnerability of foundation species in a global change hotspot


sentences: Evolutionary relationships and range evolution of greenhood orchids (subtribe Pterostylidinae): insights from plastid phylogenomics


sentences: Convergent genomic signatures of adaptation to an extreme environment in cyprinoid fishes


sentences: Fold Evolution by Creative Destruction


sentences: Macroevolutionary diversity of traits and genomes in the model yeast genus Saccharomyces


sentences: Insights into the domestication of avocado and potential genetic contributors to heterodichogamy


sentences: Felidae call type and species identification based on acoustic features

labels: animal behavior and cognition


sentences: Improved performance of biohybrid muscle-based bio-bots doped with piezoelectric boron nitride nanotubes

labels: bioengineering


sentences: An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences

labels: bioinformatics


sentences: The dynamical Matryoshka model: 3. Diffusive nature of the atomic motions contained in a new dynamical model for deciphering local lipid dynamics


sentences: Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery


sentences: Multi-omic profiling of the leukemic microenvironment shows bone marrow interstitial fluid is distinct from peripheral blood plasma


sentences: Evolutionary gain and loss of a plant pattern-recognition receptor for HAMP recognition


sentences: Dissecting Succulence: Crassulacean Acid Metabolism and Hydraulic Capacitance are Independent Adaptations in Clusia Leaves


sentences: Discussion-based DEI education to help create inclusive and open BME research lab environments

labels: scientific communication and education


sentences: Defining Predictors of Successful Early Career to Independent Funding Conversion Among Surgeon-Scientists


sentences: Pad&eacute SSA: A frequency domain method for estimating the dynamics of stochastic reaction networks


sentences: A fluctuation-based approach to infer kinetics and topology of cell-state switching


sentences: The impact of sparsity in low-rank recurrent neural networks


sentences: The role of clearance in neurodegenerative diseases


sentences: Different patterns of visual processing for shapes in V1 of mouse and monkey


sentences: Retinal ganglion cell endowment is correlated with optic tract fiber cross section, not density


sentences: Responses of cortical neurons to intracortical microstimulation in awake primates


sentences: CRISPR activation rescues abnormalities in SCN2A haploinsufficiency-associated autism spectrum disorder


sentences: Medial prefrontal-hippocampal concordance in child-parent dyads underlies children's psychological wellbeing


sentences: Autophagy slows the aging of Germline stem cells in Drosophila through modulation of E-cadherin


sentences: High predation risk decimates survival duringthe reproduction season

labels: ecology


sentences: Predicting catchment suitability for biodiversity at national scales


sentences: The genetic architecture of multiple mutualisms and mating system in Turnera ulmifolia


sentences: The genome sequence of the scarce swallowtail, Iphiclides podalirius


sentences: Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors


sentences: Cas9 targeted nanopore sequencing with enhanced variant calling improves CYP2D6-CYP2D7 hybrid allele genotyping


sentences: OTTERS: A powerful TWAS framework leveraging summary-level reference data


sentences: Robust inference of expression state in bulk and single-cell RNA-Seq using curated intergenic regions


sentences: dartR v2: an accessible genetic analysis platform for conservation, ecology, and agriculture


sentences: Improved Centromere Assemblies for RefGen_v4


sentences: A robust method for measuring social reward in adult mice


sentences: Characterization of a miniaturized ultrasound transducer customized for oral health applications


sentences: Human iPSC-Vascular Smooth Muscle Cell Spheroids Demonstrate Size-dependent Alterations in Cellular Viability and Secretory Function


sentences: Mesenchymal Stem Cells Sense the Toughness of Nanomaterials and Interfaces


sentences: RNAinsecta: A tool for prediction of pre-microRNA in insects using machine learning algorithms.


sentences: Designing microplate layouts using artificial intelligence


sentences: A Novel Sequence Labeling Framework for Extracting Drug-Protein Relations from Biomedical Literature


sentences: Small molecules from Bacopa monneiri as potent inhibitors against Neurodegenerative disorders


sentences: Does Tesla valve work for microscale active swimmers? - a computational study

labels: biophysics


sentences: Bladder cancer organoids as a functional system to model different disease stages and therapy response


sentences: Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T cell lymphoma


sentences: Transcriptional landscape in BRAF wild type metastatic melanoma


sentences: Pulmonary dust foci as rat pneumoconiosis lesion induced by titanium dioxide nanoparticles in 13-week inhalation study

labels: pathology


sentences: Frontal Cortex Gates Distractor Stimulus Encoding in Target Sensory Cortex

labels: neuroscience


sentences: Affective enhancement of episodic memory is associated with widespread patterns of intrinsic functional connectivity across the adult lifespan


sentences: Unraveling the functional attributes of the language connectome: crucial subnetworks, flexibility and variability.


sentences: Performance comparison of systemic activity correction in fNIRS for methods with and without short distance channels


sentences: EEG-representational geometries and psychometric distortions in approximate numerical judgment


sentences: The role of capacity constraints in Convolutional Neural Networks for learning random versus natural data


sentences: Normative sleep spindle database and findings from 772 healthy children from birth through 18 years


sentences: Endo-lysosomal assembly variations among Human Leukocyte Antigen class I (HLA-I) allotypes

labels: immunology


sentences: Identification of large offspring syndrome during pregnancy through ultrasonography and maternal blood transcriptome analyses


sentences: String-Pulling as a Behavioral Assessment of Skilled Forelimb Motor Function in a Middle Cerebral Artery Occlusion Rat Model


sentences: Quantitative crosslinking and mass spectrometry determine binding interfaces and affinities mediating kinetochore stabilization

labels: biochemistry


sentences: Imaging optically thick tissues simply and reproducibly: a practical guide to Lightsheet Macroscopy


sentences: Full-mouth photoacoustic/ultrasound imaging of the periodontal pocket with a compact intraoral transducer


sentences: StORF-Reporter: Finding Genes between Genes


sentences: ShrinkCRISPR : A flexible method for differential fitness analysis of CRISPR-Cas9 screen data.


sentences: Phasor-Based Multi-Harmonic Unmixing for in-vivo Hyperspectral Imaging


sentences: RNA helicase DDX5 mediates adaptive response to multi-kinase inhibitors in liver cancer


sentences: Shedding Light on the Black Box of a Neural Network Used to Detect Prostate Cancer in Whole Slide Images by Occlusion-Based Explainability


sentences: An untargeted metabolomics analysis of exogenous chemicals in human milk and transfer to the infant


sentences: Mass red blood cell extravasation and tubular uptake results in toxic injury to the tubules during kidney ischemia from venous clamping

labels: physiology


sentences: Influence of ambient day light variations and age on the Iris-pupillary area ratio in beef cattle


sentences: Effect of tempol on post-thaw semen parameters and fertility during chicken semen cryopreservation


sentences: Characterization of EDS1-independent plant defense responses against bacterial pathogens using Duckweed/Pseudomonas pathosystems

labels: plant biology


sentences: Relative stability of mRNA and protein severely limits inference of gene networks from single-cell mRNA measurements

labels: systems biology


sentences: Long-range inhibition synchronizes and updates prefrontal task activity


sentences: Impact of 98 LRRK2 variants linked to Parkinson's Disease on kinase activity and microtubule binding


sentences: Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics electrophysiological phenotype of the A53T mutation


sentences: A neural decision signal during internal sampling from working memory


sentences: Munc13 supports vesicle fusogenicity after disrupting active zone scaffolds and synaptic vesicle docking


sentences: Spatially resolved transcriptomics reveals innervation-responsive functional clusters in skeletal muscle

labels: molecular biology


sentences: Temporal and Spatial Resolution of a Protein Quake that Activates Hydrogen Tunneling in Soybean Lipoxygenase


sentences: Multi-environment genome-wide association mapping of culm morphology traits in barley


sentences: Active Anemosensing Hypothesis: How Flying Insects Could Estimate Ambient Wind Direction Through Sensory Integration & Active Movement


sentences: Targeted Proteomics and Support Vector Classification Reveal Potential Biomarkers for the Early Detection of High-grade Serous Ovarian Cancer

labels: cancer biology


sentences: GPR183 mediates the capacity of the novel CD47-CD19 bispecific antibody TG-1801 to heighten ublituximab-umbralisib (U2) anti-lymphoma activity


sentences: The mouse claustrum synaptically connects cortical network motifs


sentences: Follicular helper T cells expressing Blimp1 are specialized for plasma cell differentiation


sentences: MAIT cells activate dendritic cells to promote T follicular helper cell differentiation and humoral immunity


sentences: Rapid and accurate identification of Escherichia coli STEC O157:H7 by mass spectrometry, artificial intelligence and detection of specific biomarkers peaks.

labels: microbiology


sentences: Development of a long-read NGS workflow for improved characterization of fastidious respiratory mycoplasmas


sentences: Cell type-specific Expression Quantitative Trait Loci

labels: genomics


sentences: PanGu Drug Model: Learn a Molecule Like a Human


sentences: Prediction of brain functions from structural connectome using graph neural network


sentences: Informational Masking Can Constrain Acoustically Guided Mating Behavior


sentences: History of previous midlife estradiol treatment permanently alters interactions of brain insulin-like growth factor-1 signaling and hippocampal estrogen synthesis to enhance cognitive aging in a rat model of menopause


sentences: Hippocampal CA1 represents action and reward events instantly compared to the superficial and deep layers of the lateral entorhinal cortex


sentences: Different olfactory neuron classes use distinct temporal and molecular programs to complete synaptic development


sentences: Irrational choices via a curvilinear representational geometry for value


sentences: An Open and Continuously Updated Fern Tree of Life (FTOL)

labels: evolutionary biology


sentences: Direct and indirect impacts of positive selection on genomic variation in Drosophila serrata

labels: genetics


sentences: De novo sequencing, diploid assembly, and annotation of the black carpenter ant, Camponotus pennsylvanicus, and its symbionts by one person for $1000, using nanopore sequencing.


sentences: Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures

labels: bioinformatics


sentences: Size matters - the impact of nucleus size on results from spatial transcriptomics


sentences: Beneficial and Detrimental Effects of Nonspecific Binding During DNA Hybridization


sentences: Antibody evolution to SARS-CoV-2 after single-dose Ad26.COV2.S vaccine


sentences: In vivo prenylomic profiling in the brain of a transgenic mouse model of Alzheimer's disease reveals increased prenylation of a key set of proteins


sentences: A single vesicle fluorescence-bleaching assay for multi-parameter analysis of proteoliposomes by total internal reflection fluorescence microscopy


sentences: miRNA upregulate protein and glycan expression via direct activation in proliferating cells


sentences: Decision Tree Ensembles Utilizing Multivariate Splits Are Effective at Investigating Beta-Diversity in Medically Relevant 16S Amplicon Sequencing Data


sentences: Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity


sentences: New broad-spectrum anti-Flavivirus human antibodies with Zika virus-neutralizing potential


sentences: Recall of pre-existing cross-reactive B cell memory following Omicron breakthrough infection


sentences: Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2


sentences: Environment and the Evolutionary Trajectory of Horizontal Gene Transfer.


sentences: Frequency of change determines effectiveness of microbial response strategies in sulfidic stream microbiomes


sentences: Functional Biomarkers of Ex-vivo Dental Caries Onset


sentences: Surface microbiota of Mediterranean loggerhead sea turtles unravelled by 16S and 18S amplicon sequencing


sentences: GTP-bound E. coli FtsZ filaments are composed of Tense monomers: A DNP NMR study using interface detection.


sentences: Feedback linking cell envelope stiffness, curvature, and synthesis enables robust rod-shaped bacterial growth


sentences: The temporal transcriptomic signature of cartilage formation


sentences: Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike


sentences: Evidence that Nek1 does not phosphorylate Rad54-S572 during recovery from IR


sentences: USP18 is an essential regulator of muscle cell differentiation and maturation

labels: cell biology


sentences: HSD3B1 is an Oxysterol 3β-Hydroxysteroid Dehydrogenase in Human Placenta


sentences: Actin turnover required for adhesion-independent bleb migration


sentences: Integrative conformational ensembles of Sic1 using different initial pools and optimization methods


sentences: Head-to-head comparison of CCN4, DNMT3A, PTPN11, and SPARC as suppressors of anti-tumor immunity


sentences: Characterization of cell-fate decision landscapes by estimating transcription factor dynamics.


sentences: Physiopathological changes of ferritin mRNA density and distribution in hippocampal astrocytes in the mouse brain


sentences: Fasciola hepatica Fatty Acid Binding Protein 1 modulates T cell polarization by promoting dendritic cell thrombospondin-1 secretion without affecting metabolic homeostasis in obese mice


sentences: Omicron breakthrough infection drives cross-variant neutralization and memory B cell formation


sentences: A 3' UTR-derived small RNA connecting nitrogen and carbon metabolism in enteric bacteria


sentences: Periplasmic oxidized-protein repair during copper stress in E. coli: a focus on the metallochaperone CusF.


sentences: Comparative metagenomic analysis of biosynthetic diversity across sponge microbiomes highlights metabolic novelty, conservation and diversification


sentences: Single-Molecule Analysis of DNA-binding proteins from Nuclear Extracts (SMADNE)


sentences: Topographically distinct adaptive landscapes for skulls, skeletons, and size explain the dietary adaptive radiation of Carnivora (Mammalia)


sentences: Olfactory Sensitivity Aligns with Caste Revealing Multipotential Minors and Specialized Soldier Majors in Camponotus floridanus Ants


sentences: Efflux-linked Accelerated Evolution of Antibiotic Resistance at a Population Edge


sentences: Bacterial threat assessment of bacteriophage infection is mediated by intracellular polyamine accumulation and Gac/Rsm signaling


sentences: Allopeptimicins: unique antibacterial metabolites generated by hybrid PKS-NRPS, with original self-defense mechanism in Actinoallomurus


sentences: Overexpression of the WAPO-A1 gene increases the number of spikelets per spike in bread wheat


sentences: CryoGrid-PIXUL-RNA: High throughput RNA isolation platform for tissue transcript analysis


sentences: Spatial-CITE-seq: spatially resolved high-plex protein and whole transcriptome co-mapping


sentences: Late maturation of executive control promotes conceptual development


sentences: Explaining flexible continuous speech comprehension from individual motor rhythms


sentences: Inter-Individual Variability in Dorsal Stream Dynamics During Word Production


sentences: Robustness of the ferret model for influenza risk assessment studies: a cross-laboratory exercise


sentences: Engineering a more specific E. coli glyoxylate/hydroxypyruvate reductase for coupled steady state kinetics assays


sentences: The optimal strategy of incompatible insect technique (IIT) using Wolbachia to control Malaria


sentences: Building molecular band-pass filters via molecular sequestration

labels: synthetic biology


sentences: Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression


sentences: Pleiotrophin signals through ALK receptor to enhance growth of neurons in the presence of inhibitory CSPGs


sentences: The WalRK Two-component system is Essential for Proper Cell Envelope Biogenesis in Clostridioides difficile


sentences: Robust Variation in Infant Gut Microbiome Assembly Across a Spectrum of Lifestyles


sentences: Novel Requirement for Staphylococcal Cell Wall-Anchored Protein SasD in Pulmonary Infection


sentences: Activation of the integrative and conjugative element Tn916 causes growth arrest and death of host bacteria


sentences: Extensive heterogeneity of the HIV-1 infected CD4+ T-cell reservoir revealed by single-cell viral ASAPseq


sentences: The fluorescence-activating and absorption-shifting tag (FAST) enables live-cell fluorescence imaging of Methanococcus maripaludis


sentences: Control of pancreatic islet function and glucose homeostasis by a novel microexon program misregulated in type 2 diabetes


sentences: Mmp14-controlled extracellular matrix homeostasis is required for circadian rhythm


sentences: Xport-A functions as a chaperone by stabilizing the first 5 transmembrane domains of Rhodopsin-1


sentences: Unifying genetic association tests via regression: Prospective and retrospective, parametric and non-parametric, and genotype- and allele-based tests


sentences: Appia: a web interface for chromatography


sentences: Cotranslational folding and assembly of the dimeric E. coli inner membrane protein EmrE


sentences: Highly multiplexed targeted plasma proteomics quantifies several hundred blood proteins in serum from colorectal carcinoma patients


sentences: Clinically-relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance


sentences: Oncogenic mutations in the DNA-binding domain of FOXO1 disrupt folding: quantitative insights from experiments and molecular simulations


sentences: Microgravity enhances the phenotype of Arabidopsis zigzag-1 and reduces the Wortmannin-induced vacuole fusion in root cells


sentences: Computational design and construction of an Escherichia coli strain engineered to produce a non-standard amino acid


sentences: Reduced cutaneous CD200:CD200R1 signalling in psoriasis enhances neutrophil recruitment to skin


sentences: IMC10 and LMF1 mediate membrane contact between the mitochondrion and the inner membrane complex in Toxoplasma gondii


sentences: Artificial selection methods from evolutionary computing show promise for directed evolution of microbes


sentences: Approximations to the expectations and variances of ratios of tree properties under the coalescent


sentences: DeepAcr: Predicting Anti-CRISPR with Deep Learning


sentences: TP53 somatic mutations in Asian breast cancer are associated with subtype-specific effects


sentences: Dual pathway architecture underlying vocal learning in songbirds


sentences: A retrospective and stepwise learning strategy revealed by neuronal activity in the basal forebrain


sentences: FCHO controls AP2's critical endocytic roles through a PtdIns4,5P2 membrane-dependent switch


sentences: Reduced mitochondria provide an essential function for the cytosolic methionine cycle


sentences: A Locally Activatable Sensor for Robust Quantification of Organellar Glutathione


sentences: Death-seq identifies regulators of cell death and senolytic therapies


sentences: Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway


sentences: A dual mechanism of APC/C inhibition by MAP kinases


sentences: Surface curvature and basal hydraulic stress induce spatial bias in cell extrusion


sentences: Dietary αKG inhibits SARS CoV-2 infection and rescues inflamed lungs to restore normal O2 saturation in animals


sentences: RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia


sentences: Conformational Flexibility in Neutralization of SARS-CoV-2 by Naturally Elicited Anti-SARS-CoV-2 Antibodies


sentences: SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant


sentences: Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets


sentences: Kinetic and Redox Characterization of KRAS G12C Inhibition


sentences: Molecular basis of neurodevelopmental disorder-causing mutation in nonsense-mediated mRNA decay factor UPF3B


sentences: SEACells: Inference of transcriptional and epigenomic cellular states from single-cell genomics data


sentences: A co-operative knock-on mechanism underpins Ca2+-selective cation permeation in TRPV channels

labels: biophysics


sentences: Farnesyltransferase inhibition overcomes the adaptive resistance to osimertinib in EGFR-mutant NSCLC


sentences: NSMCE2, a Novel Super-Enhancer Regulated Gene, is Linked to Poor Prognosis and Therapy Resistance in Breast Cancer


sentences: Modulation of Receptor-like Trans-Membrane Kinase 1 nuclear localisation by DA1 peptidases in Arabidopsis.


sentences: Harnessing cellular perception apparatus for smart metabolic reprogramming


sentences: VMHdm/cSF-1 Neuronal Circuits Regulate Skeletal Muscle PGC1-α via the Sympathoadrenal Drive


sentences: M2e-specific monoclonal antibody cocktails against influenza A virus are superior to individual monoclonal antibody treatments, universally effective, and viral escape mutant resistant


sentences: Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature upon SARS-CoV-2 sensing by monocytes in COVID-19


sentences: CD169+ macrophages orchestrate plasmacytoid dendritic cell arrest and retention for optimal priming in the bone marrow of malaria-infected mice


sentences: Dynamics of drug response in single mycobacterial cells by microfluidic dose-response assay


sentences: Melanization is an important antifungal defense mechanism in Galleria mellonella hosts


sentences: Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8

labels: developmental biology


sentences: Asexual male production by ZW recombination in Artemia parthenogenetica


sentences: Allele mining, evolutionary genetic analysis of TaHKT1;5 gene and evaluation of salinity stress in selected lines of wheat.


sentences: The Bcvic1 and Bcvic2 vegetative incompatibility genes in Botrytis cinerea encode proteins with domain architectures involved in allorecognition in other filamentous fungi


sentences: Combining GWAS and TWAS to identify candidate causal genes for tocochromanol levels in maize grain


sentences: Loss-of-function mutations in novel triacylglycerol lipase genes are associated with low rancidity in pearl millet flour


sentences: Protein-Peptide Turnover Profiling reveals wiring of phosphorylation during protein maturation


sentences: Evolutionary adaptation of the folding pathway for secretability


sentences: Near-neutral pH increased n-caprylate production in a microbiome with product inhibition of methanogenesis

labels: bioengineering


sentences: Prediction of designer-recombinases for DNA editing with generative deep learning


sentences: Viability of AMURA biomarkers from single-shell diffusion MRI in Migraine Clinical Studies

labels: neuroscience


sentences: Unravelling specific diet and gut microbial contributions to inflammatory bowel disease


sentences: Saving the Devils is in the details: Tasmanian Devil facial tumor disease can be eliminated with interventions

labels: ecology


sentences: Population estimation of a cryptic moss frog using acoustic spatially explicit capture recapture


sentences: Fungal States of Minds

labels: animal behavior and cognition


sentences: Rapid loss of fine motor skills after low dose space radiation exposure


sentences: Nonlethal effects of predation: Presence of insectivorous birds affects the behaviour and level of stress in insects


sentences: A Miniaturized 3D-Printed Pressure Regulator (μPR) for Microfluidic Cell Culture Applications


sentences: Thermal Effects on Neurons During Stimulation of the Brain


sentences: Scanning Single Molecule Localization Microscopy (scanSMLM) for super-resolution optical volume imaging


sentences: Simultaneous adjustments of major mitochondrial pathways through redox regulation of dihydrolipoamide dehydrogenase (mtLPD1)

labels: plant biology


sentences: Active emulsions in living cell membranes driven by contractile stresses and transbilayer coupling


sentences: Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions


sentences: A comparison of feature selection methodologies and learning algorithms in the development of a DNA methylation-based telomere length estimator


sentences: Vimentin Intermediate Filaments Can Enhance or Abate Active Cellular Forces in a Microenvironmental Stiffness-Dependent Manner


sentences: Perturbed actin cap and nuclear morphology in primary fibroblasts of Huntington's disease patients as a new phenotypic marker for personalized drug evaluation


sentences: Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation


sentences: A brain-inspired object-based attention network for multi-object recognition and visual reasoning


sentences: Growth rate controls the sensitivity of gene regulatory circuits

labels: systems biology


sentences: Dominance vs. epistasis: the biophysical origins and plasticity of genetic interactions within and between alleles


sentences: Antibodies to Coagulase of Staphylococcus aureus crossreact to Efb and reveal different binding of shared Fibrinogen Binding repeats

labels: biochemistry


sentences: Tegaserod maleate suppresses the growth of gastric cancer in vivo and in vitro by targeting MEK1/2

labels: pathology


sentences: Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein


sentences: Accumulated 3-phosphoglycerate in darkness is a primary starting substrate for stepwise photosynthetic induction process in cyanobacteria


sentences: Emergence and clonal expansion in Europe of Vibrio aestuarianus lineages pathogenic for oysters

labels: microbiology


sentences: Anatomy and Symbiosis of the digestive system of the vent shrimps Rimicaris exoculata and Rimicaris chacei revealed through imaging approaches.


sentences: Evolutionary relations between mycorrhizal symbiosis and plant-plant communication in trees


sentences: Genomic insights into present local adaptation and future climate change vulnerability of a keystone forest tree species in East Asian


sentences: Genomic regions associate with major axes of variation in gas exchange and leaf construction traits in cultivated sunflower (Helianthus annuus L.)


sentences: Combined drought resistance strategies and the hydraulic limit in co-existing Mediterranean woody species


sentences: Cellular dynamics of endosperm development in Arabidopsis thaliana


sentences: A scalable phenotyping approach for female floral organ development and senescence in the absence of pollination in wheat


sentences: Toxoplasma gondii Coq1 is a heptaprenyl diphosphate synthase and its inhibition by a lipophilic bisphosphonate protects mice against T. gondii infection


sentences: Intracellular acidification is a hallmark of thymineless death in E. coli


sentences: Unique genomic sequences in novel Mycobacterium avium subsp. hominissuis lineage enabled fine scale tracing the transmission route during pig movement


sentences: Differential pathogenesis of SARS-CoV-2 variants of concern in human ACE2-expressing mice


sentences: Neuroendocrine control of the proteostatic network by HPK-1 delays aging


sentences: Transmembrane helices 5 and 12 control transport dynamics, substrate affinity and specificity in the elevator-type UapA transporter


sentences: Structure and function of a Notch-like proteolytic switch domain in the extracellular matrix receptor dystroglycan


sentences: Unbreakable DNA tension probes show that cell adhesion receptors detect the molecular force-extension curve of their ligands


sentences: Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome


sentences: Older circuits get richer: neurogenesis timeline shapes hubness and neurogenetic profiles of the adult human brain


sentences: CCR4 and CCR7 differentially regulate thymocyte subset localization with distinct outcomes for central tolerance

labels: immunology


sentences: Identification and functional characterization of two heme uptake systems required for virulence of the fish pathogen Flavobacterium psychrophilum


sentences: Modulation of the gut microbiome by novel synthetic glycans for the production of propionate and the reduction of cardiometabolic risk factors


sentences: Moxifloxacin-mediated killing of Mycobacterium tuberculosis involves respiratory downshift, reductive stress, and ROS accumulation


sentences: Anthropogenic disturbance impacts gut microbiome homeostasis in a Malagasy primate


sentences: Evidence for a widespread third system for bacterial polysaccharide export across the outer membrane comprising a composite OPX/β-barrel translocon


sentences: Re-engineering of CUP1 promoter and Cup2/Ace1 transactivator to convert Saccharomyces cerevisiae into a whole-cell eukaryotic biosensor capable of detecting 10 nM of bioavailable copper

labels: molecular biology


sentences: Nrf2 prevents diabetic cardiomyopathy via antioxidation and normalization of glucose and lipid metabolism in the heart


sentences: Overactive mitochondrial DNA replisome causes neonatal heart failure via ferroptosis


sentences: Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.


sentences: Rheology of growing axons


sentences: Western spotted skunks provide important food web linkages in forest of the Pacific Northwest


sentences: hemispheR: an R package for fisheye canopy image analysis


sentences: Genomic legacies of ancient adaptation illuminate the GC-content evolution in bacterial genomes

labels: evolutionary biology


sentences: Comparing evolvability and pleiotropy across environments


sentences: Mechanism-based crosslinking probes capture E. coli ketosynthase FabB in conformationally-distinct catalytic states.


sentences: Nuclease proteins CifA and CifB promote spermatid DNA damage associated with symbiont-induced cytoplasmic incompatibility


sentences: Structural and Preliminary Biochemical Characterization of MppQ, a PLP-Dependent Aminotransferase from 	Streptomyces hygroscopicus


sentences: Engineering functional membrane-membrane interface by InterSpy


sentences: Screening candidate genes related to psoas muscle traits in Debao and Landrace pigs based on transcriptome analysis

labels: genomics


sentences: Lumbar time-varying muscle synergies in trunk flexion and bending movements at different velocities


sentences: MAECI: A Pipeline For Generating Consensus Sequence With Nanopore Sequencing Long-read Assembly and Error Correction

labels: bioinformatics


sentences: Collagen remodeling dictates pancreatic cancer bioenergetics and outcome through DDR1 activation or degradation

labels: cancer biology


sentences: Biological responses to terahertz radiation with different power density in primary hippocampal neurons


sentences: Sub-type selective muscarinic acetylcholine receptor modulation for the treatment of parkinsonian tremor


sentences: Molecular differences in APOBEC3 counteraction by primate herpesviruses reveal an evolutionary link between the genesis of APOBEC3B and novel viral ribonucleotide reductase function


sentences: Surface detection of SARS-CoV-2 by lateral flow LAMP

labels: genetics


sentences: Melanoma cells release DEL-1 via small extracellular vesicles


sentences: Gut Enterochromaffin Cells are Critical Drivers of Visceral Pain and Anxiety

labels: physiology


sentences: Cholinergic stimulation modulates the functional composition of CA3 cell types in the hippocampus


sentences: Transcriptional Heterogeneity and Cell Cycle Regulation as Central Determinants of Primitive Endoderm Priming.

labels: developmental biology


sentences: The angular gyrus is engaged by autobiographical recall not object-semantics, or event-semantics: Evidence from contrastive propositional speech production

labels: neuroscience


sentences: Molecular dissection of condensin II-mediated chromosome assembly using in vitro assays

labels: cell biology


sentences: Chromatin regulates genome-wide transcription factor binding affinities


sentences: Socially learned arbitrary call use in a wild primate

labels: animal behavior and cognition


sentences: One-trial social learning of vervet monkey alarm calling


sentences: Genetically encoded sensors for analysing neurotransmission among synaptically-connected neurons


sentences: Emergence of distinct neural subspaces in motor cortical dynamics during volitional adjustments of ongoing locomotion


sentences: Human statistical learning dynamically shapes the hippocampal processing of temporal associations


sentences: A deep hierarchy of predictions enables assignment of semantic roles in real-time speech comprehension


sentences: Comprehensive Structural Variant Detection: From Mosaic to Population-Level


sentences: Immediate predation risk alters the relationship between potential and realised selection on male traits in the Trinidad guppy Poecilia reticulata


sentences: A playback paradox? Nathusius' bats, Pipistrellus nathusii, bypass mating and fueling opportunities on migratory transit flights


sentences: Species-typical chemical signals mediate reproductive isolation in a teleost fish


sentences: GoFish: A low-cost, open-source platform for closed-loop behavioural experiments on fish


sentences: Delayed dynamics of migratory response to CTLA-4 blockade reveals a mechanistic view on potential T cells reinvigoration following immune checkpoint blockade


sentences: In Utero Activation of NK Cells in Congenital CMV Infection


sentences: Decision heuristics in contexts exploiting intrinsic skill


sentences: Bmal1-knockout mice exhibit reduced cocaine-seeking behaviour and cognitive impairments


sentences: Factors determining distributions of rainforest Drosophila shift from interspecific competition to high temperature with decreasing elevation

labels: ecology


sentences: Newfoundland and Labrador: A mosaic founder population of an Irish and British diaspora from 300 years ago.


sentences: Estimates of in vivo turnover numbers by simultaneously considering data from multiple conditions improve metabolic predictions


sentences: Reproducible stool metagenomic biomarkers linked to the melanoma immunotherapy positive outcome


sentences: Age at cancer diagnosis by breed, weight, sex, and cancer type in a cohort of over 3,000 dogs: determining the optimal age to initiate cancer screening in canine patients


sentences: Functional autapses form in striatal parvalbumin interneurons but not medium spiny neurons


sentences: Trait anxiety is associated with hidden state inference during aversive reversal learning


sentences: Visuo-tactile integration in texture perception: A replication and extension study


sentences: Cellular and Molecular Organization of the Rhesus Macaque Dorsal Horn with a Comparison to Mouse


sentences: Nonlinear Parameter and State Estimation Approach in End-stage Kidney Disease Patients

labels: bioengineering


sentences: Factors regulating translation coupled mRNA degradation in yeast


sentences: GenMPI: Cluster Scalable Variant Calling forShort/Long Reads Sequencing Data


sentences: LENS - Landscape of Effective Neoantigens Software


sentences: Tackling polypharmacology of kinase inhibitors by transcription factor activity profiling.

labels: pharmacology and toxicology


sentences: Speed-dependent biomechanical changes vary across individual gait metrics post-stroke relative to neurotypical adults


sentences: Cue-driven motor planning facilitates express visuomotor responses in human arm muscles


sentences: An open-source, ready-to-use and validated ripple detector plugin for the Open Ephys GUI


sentences: Functional Cell Types in the Mouse Superior Colliculus


sentences: Microstructural alterations in tract development in college football: a longitudinal diffusion MRI study


sentences: Separation of NaV Subtypes in the Axon InitialSegment can Impede or Promote Backpropagation


sentences: Brain-heart interactions are optimized across the respiratory cycle via interoceptive attention


sentences: Stochastic analysis of frequency bandwidth and noise attenuation in neurotransmission


sentences: Persistent pervasive transcription in RNA exosome depleted oocytes results in loss of female fertility


sentences: Bird community structure in a mixed forest-production landscape in the northern Western Ghats, India


sentences: Evolutionary responses of a reef-building coral to climate change at the end of the last glacial maximum


sentences: Behavioral dysregulation and monoaminergic deficits precede memory impairments in human tau-overexpressing (htau) mice


sentences: Lumbar time-varying muscle synergies in trunk flexion and bending movements at different velocities


sentences: Machine Learning Classification Reveals Robust Morphometric Biomarker of Glial and Neuronal Arbors


sentences: A computational modeling of primary-microRNA expression


sentences: Cellpose 2.0: how to train your own model


sentences: Motifizer: a tool for parsing high-throughput sequencing datasets and quantitative comparative analyses of transcription factor-binding sites


sentences: Single-cell multimodal modeling with deep parametric inference


sentences: epiAneufinder: identifying copy number variations from single-cell ATAC-seq data


sentences: Communication-Efficient Cluster Scalable Genomics Data Processing Using Apache Arrow Flight


sentences: Elongated exons encoding disordered regions expedited eukaryotic evolution


sentences: A multiscale whole-cell theory for mechano-sensitive migration on viscoelastic substrates

labels: biophysics


sentences: Drug addiction mutations unveil a methylation ceiling in EZH2-mutant lymphoma


sentences: A paracrine circuit of IL-1b/IL-1R1 between myeloid and tumor cells drives glioblastoma progression


sentences: Laboratory evolution of synthetic electron transport system variants reveals a larger metabolic respiratory system and its plasticity

labels: systems biology


sentences: Chronic hM3Dq-DREADD mediated chemogenetic activation of parvalbumin-positive inhibitory interneurons in postnatal life alters anxiety and despair-like behavior in adulthood in a task and sex-dependent manner


sentences: The Insulin receptor regulates the persistence of mechanical nociceptive sensitization in flies and mice


sentences: Bidirectional modulation of neuronal excitability via ionic actuation of potassium


sentences: The influence of stereopsis on visual saliency in a proto-object based model of selective attention


sentences: Information theory characteristics improve the prediction of lithium response in bipolar disorder patients using an SVM classifier


sentences: DomeVR: A setup for experimental control of an immersive dome virtual environment created with Unreal Engine 4


sentences: Functional coupling of the mesencephalic locomotor region and V2a reticulospinal neurons driving forward locomotion


sentences: Firing behavior of single motor neurons of the tibialis anterior in human walking as non-invasively revealed by HDsEMG decomposition


sentences: Kidins220 regulates the development of B cells bearing the {lambda} light chain

labels: immunology


sentences: Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands


sentences: T cell-mediated development of stromal fibroblasts with an immune-enhancing chemokine profile


sentences: Climate change will redefine taxonomic, functional, and phylogenetic diversity patterns of Odonata in space and time


sentences: Prey resources are more important than climatic conditions for predicting the distribution of a broad-ranged apex predator


sentences: Systematic identification of unannotated ORFs in Drosophila reveals evolutionary heterogeneity


sentences: The genetic architectures of vine and skin maturity in tetraploid potato


sentences: Remodeling of gene regulatory networks underlying thermogenic stimuli-induced adipose beiging


sentences: A Self-Purifying Microfluidic System for Identifying Drugs Acting Against Adult Schistosomes


sentences: Engineering Proprioceptive Implants via Surgical and Regenerative Approaches: Preliminary Interpretations


sentences: Noncoding RNA's competing endogenous gene pair as motif in serous ovarian cancer


sentences: Principal component analysis- and tensor decomposition-based unsupervised feature extraction to select more reasonable differentially methylated cytosines: Optimization of standard deviation versus state-of-the-art methods


sentences: DeepToA: An Ensemble Deep-Learning Approach to Predicting the Theater of Activity of a Microbiome


sentences: Talin-drug interaction reveals a key molecular determinant for biphasic mechanical effect: studied under single-molecule resolution


sentences: Tumor spheroids accelerate persistently invading cancer cells


sentences: Loss of HOXA10 causes endometrial hyperplasia progressing to endometrial cancer


sentences: The catalytic domain of cellulose synthase (CESA) is involved in vesicle trafficking and protein dynamics

labels: plant biology


sentences: Sloppiness: fundamental study, new formalism and quantification


sentences: Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development


sentences: Perivascular SPP1 Mediates Microglial Engulfment of Synapses in Alzheimers Disease Models


sentences: Effect of LSD and music on the time-varying brain dynamics


sentences: Delay-related activity in marmoset prefrontal cortex


sentences: Dichotomic Regulation of Striatal Plasticity by Dynorphin


sentences: Overactivation of a sleep-active neuron decouples survival from the need to sleep


sentences: All-optical visualization of specific molecules in the ultrastructural context of brain tissue


sentences: Neuronal nuclear calcium signaling suppression of microglial reactivity is mediated by osteoprotegerin after traumatic brain injury


sentences: Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with poor neurological outcomes after cardiac arrest


sentences: A one-step CRISPR-based strategy for endogenous gene tagging in Drosophila melanogaster

labels: molecular biology


sentences: Detection and molecular characterization of a phytoplasma associated with Cucumber (Cucumis sativus) and its first report from India


sentences: Transcriptional profiling from whole embryos to single neuroblast lineages in Drosophila


sentences: Colouring coral larvae for tracking dispersal


sentences: Community adaptation to temperature explains abrupt soil bacterial community shift along a geothermal gradient on Iceland


sentences: NUMT PARSER: automated identification and removal of nuclear mitochondrial pseudogenes (numts) for accurate mitochondrial genome reconstruction in Panthera

labels: evolutionary biology


sentences: Full-length dystrophin is expressed across human tissues and DMD downregulation commonly occurring in tumours coincides with Duchenne-like molecular alterations


sentences: Active vision during prey-capture in wild marmoset monkeys


sentences: Microenvironmental engineering improves the self-organization of patterned microvascular networks


sentences: Systematic classification error profoundly impacts inference in high-depth Whole Genome Shotgun Sequencing datasets

labels: bioinformatics


sentences: recolorize: improved color segmentation of digital images (for people with other things to do)


sentences: A Deep Learning Method for MiRNA/IsomiR Target Detection


sentences: DeepVelo: Deep Learning extends RNA velocity to multi-lineage systems with cell-specific kinetics


sentences: Molecular-Dynamics Simulation Methods for Macromolecular Crystallography


sentences: Characterizing the extracellular matrix transcriptome of cervical, endometrial, anduterine cancers

labels: cancer biology


sentences: 3'UTR-dependent dynamic changes in TP53 mRNA localization regulate p53 tumor suppressor activity


sentences: Increased adipose tissue indices of androgen catabolism and aromatization in women with metabolic dysfunction


sentences: Electron tomography analysis of the prolamellar body and its transformation into grana thylakoids in the cryofixed Arabidopsis cotyledon


sentences: Ralstonia solanacearum effector RipAF1 ADP-ribosylates host FBN1 to induce resistance against bacterial wilt


sentences: ASTF1, an AP2/ERF-family transcription factor and ortholog of cultivated tomato LEAFLESS, is required for acylsugar biosynthesis


sentences: Gut microbiome-linked metabolites in the pathobiology of depression and anxiety - a role for bile acids


sentences: Cognitive dysfunction and anxiety resulted from synaptic downscaling, hippocampal atrophy and ventricular enlargement in i.c.v. streptozotocin injected male Wistar rats


sentences: Application of light-sheet mesoscopy to image host-pathogen interactions in intact organs


sentences: Small silencing RNAs expressed from W-linked retrocopies of Masculinizer target the male-determining gene PxyMasc during female sex determination in the Diamondback moth Plutella xylostella


sentences: mRNAid, an Open-Source Platform for Therapeutic mRNA Design and Optimization Strategies


sentences: Reduced stroke outcome in old-aged female mice maintained on a dietary vitamin B12 deficiency


sentences: Microglia Detect Externalized Phosphatidylserine on Synapses for Elimination via TREM2 in Alzheimer's Disease Models


sentences: Tissue-wide Genetic and Cellular Landscape Shapes the Execution of Sequential PRC2 Functions in Neural Stem Cell Lineage Progression


sentences: Mice expressing P301S mutant human tau have deficits in interval timing


sentences: High-level motor planning allows flexible walking at different gait patterns in a neuromechanical model


sentences: Neural systems underlying RDoC social constructs: An activation likelihood estimation meta-analysis


sentences: Substance P and adenosine signaling pathways regulate exosomal sorting of miR-21 in colonic epithelial cells


sentences: Methacrylic acid-based biomaterials promote peripheral innervation in the subcutaneous space of mice


sentences: A Python Package for the Localization of Protein Modifications in Mass Spectrometry Data


sentences: Immunopharmacological evaluation of adjuvant efficacy of Monophosphoryl lipid-A and CpG ODN with SARS-CoV-2 RBD antigen


sentences: Impact of prior infection on SARS-CoV-2 antibody responses in vaccinated long-term care facility staff


sentences: Screening of SARS-CoV-2 Antivirals Through a Cell-Based RNA-Dependent RNA Polymerase (RdRp) Reporter Assay

labels: microbiology


sentences: Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection


sentences: Evolution of Delta variant by non-Spike signature co-appearing mutations: trailblazer of COVID-19 disease outcome

labels: genomics


sentences: Time series analysis of SARS-CoV-2 genomes and correlations among highly prevalent mutations


sentences: The network of SARS-CoV-2-cancer molecular interactions and pathways


sentences: The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito


sentences: Tracing carbon metabolism with stable isotope metabolomics reveals the legacy of diverse carbon sources in soil


sentences: Divergent LD-transpeptidase-independent effects of peptidoglycan carboxypeptidases on intrinsic ss-lactam and vancomycin resistance


sentences: The impact of PrsA over-expression on the Bacillus subtilis transcriptome during fed-batch fermentation of alpha-amylase production


sentences: Transmission of human influenza A virus in pigs selects for adaptive mutations on the HA gene


sentences: FLAGELLAR MOTILITY DURING E. COLI BIOFILM FORMATION PROVIDES A COMPETITIVE DISADVANTAGE WHICH RECEDES IN THE PRESENCE OF CO-COLONIZERS.


sentences: TransCRISPR - sgRNA design tool for CRISPR/Cas9 experiments targeting transcription factor motifs


sentences: Parental histone distribution at nascent strands controls homologous recombination during DNA damage tolerance


sentences: Revealing determinants of translation efficiency via whole-gene codon randomisation and machine learning


sentences: CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever


sentences: Distinct regions of H. pylori's bactofilin regulate protein interactions to control cell shape


sentences: Single-cell transcriptomics to define Plasmodium falciparum stage-transition in the mosquito midgut


sentences: Description of Halopseudomonas maritima sp. nov., based on phylogenomic analysis


sentences: Enhancing Prime Editing Efficiency and Flexibility with Tethered and Split pegRNAs


sentences: Development of ultra-low-input nanoRibo-seq enables quantification of translational control, revealing broad uORF translation by subtype-specific neurons


sentences: Cryo-EM Structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids


sentences: m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site


sentences: Microclimate is a strong predictor of the native and invasive plant-associated soil microbiota on San Cristobal Island, Galapagos archipelago


sentences: Comparative analysis about the structure of complete chloroplast genomes in genus Mangifera and accuracy verification about phylogenetic analysis based on gene ycf2 in genus level


sentences: Nucleoporins facilitate ORC loading onto chromatin


sentences: How to select the best model from AlphaFold2 structures?


sentences: Identification of Antimalarial Compounds that Inhibit Apicomplexan AP2 Proteins


sentences: Protist diversity and metabolic strategy in freshwater lakes are shaped by trophic state and watershed land use at a continental scale


sentences: Non-cancer stem cell-derived Fibromodulin activates Integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth


sentences: Toward an optimal contraception dosing strategy


sentences: Vascular inflammation exposes perivascular cells to SARS-CoV-2 infection


sentences: ViReMaShiny: An Interactive Application for Analysis of Viral Recombination Data


sentences: Delineating antibody escape from Omicron variants


sentences: SARS-CoV-2 Omicron (BA.1 and BA.2) specific novel CD8+ and CD4+ T cell epitopes targeting spike protein.


sentences: Delta-Omicron recombinant SARS-CoV-2 in a transplant patient treated with Sotrovimab


sentences: CARP2 regulates the Golgi dynamics upon EGF stimulation


sentences: Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase


sentences: Introducing CELLBLOKS: a novel organ-on-a-chip platform allowing a plug-and-play approach towards building organotypic models


sentences: Redox sensing by SENP1 augments insulin secretion early after high-fat feeding in mice


sentences: Salicin modifies osteoarthritis progression by binding on IRE1α and inhibiting IRE1α mediated endoplasmic reticulum stress


sentences: Conserved degronome features governing quality control-associated proteolysis


sentences: Cryo-EM reveals an entangled kinetic trap in the folding pathway of a catalytic RNA

labels: biochemistry


sentences: Exploring the effect of mechanical anisotropy of protein structures in the unfoldase mechanism of AAA+ molecular machines


sentences: State Dependent Anionic Pore Currents Conducted by Single Countercharge Mutants in a Voltage-Sensing Phosphatase


sentences: Advanced transcriptomic analysis reveals the role of efflux pumps and media composition in antibiotic responses of Pseudomonas aeruginosa


sentences: An Ultralong Bovine CDRH3 that Targets a Conserved, Cryptic Epitope on SARS-CoV and SARS-CoV-2


sentences: Impact of energy limitations on function and resilience in long-wavelength Photosystem II


sentences: Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation, and ssDNA binding kinetics


sentences: Deep Local Analysis evaluates protein docking conformations with locally oriented cubes


sentences: Architecture of the chikungunya virus replication organelle


sentences: Copper binding leads to increased dynamics in the regulatory N-terminal domain of full-length human copper transporter ATP7B


sentences: Overexpression of TopBP1 leads to transformation with a TP53 mutation of non-tumorigenic breast epithelial cells


sentences: Nitroimidazopyrazinones with oral activity against tuberculosis and Chagas disease in mouse models of infection


sentences: PEP7 is a ligand for receptor kinase SIRK1 to regulate aquaporins and root growth


sentences: The potyviral protein 6K2 from Turnip mosaic virus increases plant resilience to drought


sentences: Screening of the optimal CpG-oligodeoxynucleotide for anti-inflammatory responses in avian macrophage cell line HD11


sentences: Evidence for complex interplay between quorum sensing and antibiotic resistance in Pseudomonas aeruginosa


sentences: Extended genomic analyses of the broad-host-range phages vB_KmiM-2Di and vB_KmiM-4Dii reveal slopekviruses have highly conserved genomes


sentences: A positive feedback loop controls Toxoplasma chronic differentiation


sentences: Dental pulp metagenomics reveals ancient human Herpesviridae.


sentences: Culexarchaeia, a novel archaeal class of anaerobic generalists inhabiting geothermal environments


sentences: Using Culture-Enriched Phenotypic Metagenomics for Targeted High-Throughput Monitoring of Clinically-Important Fraction of Beta-Lactam Resistome


sentences: Unexpected Complexity of the Ammonia Monooxygenase in Archaea


sentences: Barcoding genetically distinct Plasmodium falciparum strains for comparative assessment of fitness and antimalarial drug resistance