sentences: Design principles to assemble drug combinations for effective tuberculosis therapy using interpretable pairwise drug response measurements


sentences: Salmonella enterica serovar Typhimurium chitinases modulate the intestinal glycome and promote small intestinal invasion.

labels: microbiology


sentences: Polyunsaturated fatty acid arachidonic acid increases the virulence of gut pathogen, Yersinia enterocolitica


sentences: Predictions of the SARS-CoV-2 Omicron Variant (B.1.1.529) Spike Protein Receptor-Binding Domain Structure and Neutralizing Antibody Interactions

labels: molecular biology


sentences: A two-step metagenomics approach for prey identification from the blood meals of common vampire bats (Desmodus rotundus)


sentences: Cistrome and transcriptome analysis identifies unique androgen receptor (AR) and AR- V7 splice variant chromatin binding and transcriptional activities


sentences: TRAP1 and cyclophilin D compete at OSCP subunit to regulate enzymatic activity and permeability transition pore opening by F-ATP synthase

labels: cell biology


sentences: THO and TRAMP complexes prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions

labels: genetics


sentences: Mathematical expressions describing enzyme velocity and inhibition at high enzyme concentration

labels: biochemistry


sentences: Creation of photocyclic vertebrate rhodopsin by single amino acid substitution


sentences: FPCountR: Absolute quantification of fluorescent proteins for synthetic biology

labels: synthetic biology


sentences: ARBRE: Computational resource to predict pathways towards industrially important aromatic compounds


sentences: Evaluation of odorant-binding protein-1 as a molecular marker for identifying biological forms and delimitating sibling species of Anopheles stephensi


sentences: Tailer: A Pipeline for Sequencing-Based Analysis of Non-Polyadenylated RNA 3' End Processing


sentences: Ca2+ Mediates HIF-dependent Upregulation of Aquaporin 1 in Pulmonary Arterial Smooth Muscle Cells


sentences: Genetic conversion of a split-drive into a full-drive element


sentences: Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation

labels: genomics


sentences: Functional Anatomy of the TDP-43 Redox Sensor


sentences: Tracing the genetics of neurological disease to the mutation-directed addition of single hydrogen bonds


sentences: SAVED by a toxin: Structure and function of the CRISPR Lon protease.


sentences: Modeling the trajectory of SARS-CoV-2 spike protein evolution in continuous latent space using a neural network and Gaussian process

labels: bioinformatics


sentences: Pandemic-scale phylogenetics


sentences: miR-199-3p Suppresses Cellular Migration and Viability and Promotes Progesterone Production in Goose Ovarian Follicles Before Selection by Targeting ITGB8 and Regulating Other ECM-related Genes


sentences: Chromatin accessibility differences between alpha, beta, and delta cells identifies common and cell type-specific enhancers


sentences: Deltamethrin contact exposure mediated toxicity and histopathological aberrations in tissue systems of cockroach species Periplaneta americana and Blatella germanica

labels: zoology


sentences: Dairy vs. beef production - expert views on welfare

labels: animal behavior and cognition


sentences: The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes


sentences: Escherichia coli antimicrobial resistance; Phenotypic and genotypic characterization


sentences: Sexual and developmental variations of ecto-parasitism in damselflies

labels: evolutionary biology


sentences: Aggregation chimeras provide evidence of in vivo intercellular correction in ovine CLN6 neuronal ceroid lipofuscinosis (Batten disease)

labels: neuroscience


sentences: Heterozygous transcriptional and nonsense decay signatures in blood outgrowth endothelial cells from patients with hereditary haemorrhagic telangiectasia


sentences: Tubulinopathy mutations in TUBA1A that disrupt neuronal morphogenesis and migration override XMAP215/Stu2 regulation of microtubule dynamics


sentences: Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration


sentences: Age-dependent aggregation of ribosomal RNA-binding proteins links deterioration in chromatin stability with loss of proteostasis


sentences: Nucleotide imbalance decouples cell growth from cell proliferation


sentences: Exophers are components of mammalian cell neurobiology in health and disease


sentences: Rab40c Regulates Focal Adhesions and Protein Phosphatase 6 Activity by Controlling ANKRD28 Ubiquitylation and Degradation


sentences: Ubiquitination regulates cytoophidium assembly in Schizosaccharomyces pombe


sentences: Prdm16 and Notch functionally and physically interact during artery development

labels: developmental biology


sentences: Tissue-specific inhibition of protein sumoylation uncovers diverse SUMO functions during C. elegans vulval development


sentences: Patterned mechanical feedback establishes a global myosin gradient


sentences: Subcellular spatial transcriptomics identifies three mechanistically different classes of localizing RNAs


sentences: Distributed Feedforward and Feedback Processing across Perisylvian Cortex Supports Human Speech


sentences: The Petasites hybridus CO2-extract (Ze 339) blocks SARS-CoV-2 replication in vitro

labels: pharmacology and toxicology


sentences: Seroprevalence of brucellosis and molecular characterization of Brucella spp. from slaughtered cattle in Rwanda


sentences: Decrowding Expansion Pathology: Unmasking Previously Invisible Nanostructures and Cells in Intact Human Brain Pathology Specimens

labels: bioengineering


sentences: Efemp1 modulates elastic fiber formation and mechanics of the extrahepatic bile duct

labels: physiology


sentences: Traditional martial arts and shooting training have different effects on auditory fine structure processing ability---Evidence from behavioral tests and fMRI


sentences: Disrupted controlling mechanism of salience network on default-mode network and central-executive network in schizophrenia


sentences: The Effect of Spatial Frequency on the Visual Category Representation in the Macaque Inferior Temporal Cortex


sentences: Vestibular Agnosia is linked to abnormal functional brain networks


sentences: Modulation of behavioral and hippocampal transcriptomic responses in rat prolonged chronic unpredictable stress model by fluoxetine, eicosapentaenoic acid and lipopolysaccharide


sentences: Changes in natural transformation after salt adaptation


sentences: Improving replicability using interaction with laboratories: a multi-lab experimental assessment


sentences: Inference of Brain States under Anesthesia with Meta Learning Based Deep Learning Models


sentences: A novel paradigm for optimal mass feature peak picking in large scale LC-MS datasets using the isopair: isoLock, autoCredential and anovAlign


sentences: PIPP: Improving peptide identity propagation using neural networks


sentences: scBERT: a Large-scale Pretrained Deep Langurage Model for Cell Type Annotation of Single-cell RNA-seq Data


sentences: Control of nuclear size by osmotic forces in Schizosaccharomyces pombe

labels: biophysics


sentences: Characterization of epigenetic alterations in esophageal cancer by whole-genome bisulfite sequencing

labels: cancer biology


sentences: Type-I interferon signaling is essential for robust metronomic chemo-immunogenic tumor regression in murine triple-negative breast cancer


sentences: NAD metabolism modulates mitochondrial function and inflammation and prevents progression of diabetic kidney disease

labels: pathology


sentences: Quantitative genetic analysis of interactions in the pepper-Phytophthora capsici pathosystem

labels: plant biology


sentences: Characteristics and data reporting of rare disease clinical trials: Getting better but still room for improvement

labels: scientific communication and education


sentences: Met/HGFR triggers detrimental reactive microglia in TBI


sentences: Interoceptive sensitivity modulates heart rate and insula activity when listening to music


sentences: Visualizing cell death in live retina: Using calpain activity detection as a biomarker for retinal degeneration


sentences: Computational simulations and Ca2+ imaging reveal that slow synaptic depolarizations (slow EPSPs) inhibit fast EPSP evoked action potentials for most of their time course in enteric neurons


sentences: A tool for the in vivo gating of gene expression in neurons using the co-occurrence of neural activity and light


sentences: Endurance exercise ameliorates phenotypes in Drosophila models of Spinocerebellar Ataxias


sentences: Sleep Dependent Changes of Lactate Concentration in Human Brain


sentences: Utilizing occupancy-detection models with museum specimen data: promise and pitfalls

labels: ecology


sentences: Growth rate as a modulator of tooth patterning during adaptive radiations


sentences: Meta Analysis of the Ralstonia solanacearum species complex (RSSC) based on comparative evolutionary genomics and reverse ecology


sentences: Low-affinity CAR T cells exhibit reduced trogocytosis, preventing fratricide and antigen-negative tumor escape while preserving anti-tumor activity


sentences: panModule: detecting conserved modules in the variable regions of a pangenome graph


sentences: Mitochondrial mutational spectrum is associated with mammalian longevity: a novel signature of oxidative damage.


sentences: Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami


sentences: Tissue remodeling and cell signaling underpin changes in tumor microenvironment heterogeneity in glioma oncogenesis


sentences: Cathelicidin-3 associated with serum extracellular vesicles enables early diagnosis of a transmissible cancer


sentences: Leveraging a physiologically based quantitative translational modeling platform for designing bispecific T cell engagers for treatment of multiple myeloma


sentences: High School Science Fair: Ethnicity Trends in Student Participation and Experience


sentences: Molecular Mechanisms of Neurotransmitter Release Control Distinct Features of Sensory Coding Reliability


sentences: Selective representations of texture and motion in mouse higher visual areas


sentences: Microevidence for microdosing with psilocybin mushrooms: a double-blind placebo-controlled study of subjective effects, behavior, creativity, perception, cognition, and brain activity


sentences: Short latency stretch reflexes depend on the balance of activity in agonist and antagonist muscles during ballistic elbow movements


sentences: Disentangling hand and tool processing: distal effects of neuromodulation


sentences: Task-dependent switching of feedback controllers


sentences: Neural dynamics of causal inference in the macaque frontoparietal circuit


sentences: Response plasticity of Drosophila olfactory sensory neurons


sentences: PACAP-PAC1 Receptor Inhibition is Effective in Models of Opioid-Induced Medication Overuse Headache


sentences: MitoVisualize: A resource for analysis of variants in human mitochondrial RNAs and DNA

labels: genetics


sentences: The accuracy of absolute differential abundance analysis from relative count data

labels: genomics


sentences: Interplay between stress and reproduction: Novel epigenetic markers in response to shearing patterns in Australian Merino sheep (Ovis aries)


sentences: Among-individual variation of risk-taking behaviour in group and solitary context is uncorrelated but independently repeatable in a juvenile Arctic charr (Salvelinus alpinus) aquaculture strain.


sentences: PEDOT:PSS-Modified Cotton Conductive Thread for Mass Manufacturing of Textile-Based Electrical Wearable Sensors by Computerized Embroidery


sentences: MIRA: Joint regulatory modeling of multimodal expression and chromatin accessibility in single cells

labels: bioinformatics


sentences: Degradation of lactoferrin caused by droplet atomization process via two fluid nozzle: The detrimental effect of air water interfaces


sentences: EpyNN: Educational python for Neural Networks


sentences: A luciferase prosubstrate and a red bioluminescent calcium indicator to image neuronal activity


sentences: A deep learning-based multisite neuroimage harmonization framework established with traveling-subject dataset


sentences: Graded variation in cortical T1w/T2w myelination during adolescence


sentences: Learning Active Multimodal Subspaces in the Brain


sentences: Sociodemographic effects on immune cell composition in a free-ranging non-human primate.

labels: immunology


sentences: The SUMO protease Ulp2 regulates genome stability and drug resistance in the human fungal pathogen Candida albicans

labels: microbiology


sentences: Power laws from the bird species abundance distribution


sentences: Dispersal syndrome and landscape fragmentation in the salt-marsh specialist spider Erigone longipalpis


sentences: Floral evolution and pollinator diversification in Hedychium J.Koenig (Zingiberaceae): one of Mr. Darwin's tropical fantasies

labels: evolutionary biology


sentences: Stepwise evolution of a butterfly supergene via duplication and inversion


sentences: Summary statistics knockoff inference empowers identification of putative causal variants in genome-wide association studies


sentences: Frontal plane ankle stiffness increases with axial load independent of muscle activity


sentences: Through-plane super-resolution with autoencoders in diffusion magnetic resonance imaging of the developing human brain


sentences: TargetGeneReg 2.0: a comprehensive web-atlas for p53, p63, and cell cycle-dependent gene regulation


sentences: Graphsite: ligand-binding site classification using deep graph neural network


sentences: Control of Leaf Vein Patterning by Regulated Plasmodesma Aperture


sentences: Phosphorylation dynamics in a flg22 induced, heterotrimeric G protein dependent signaling network in Arabidopsis thaliana reveals a candidate PP2A phosphatase involved in AtRGS1 trafficking

labels: systems biology


sentences: Neuronal population activity dynamics reveal a low-dimensional signature of operant learning

labels: neuroscience


sentences: Visual imagery vividness declines across the lifespan


sentences: Transactive response DNA-binding Protein (TDP-43) regulates early HIV-1 entry and infection.


sentences: EB3-informed dynamics of the microtubule stabilizing cap during stalled growth

labels: cell biology


sentences: Slit-Robo Signalling Establishes a Sphingosine-1-Phosphate Gradient to Polarise Fin Mesenchyme and Establish Fin Morphology


sentences: The war of corals: patterns, drivers, and implications of changing coral competitive performances across reef environments


sentences: Using simulated temperature regimes to test growth and development of an invasive forest insect under climate change


sentences: Experimental calibration of trapping methods for addressing bias in arthropod biodiversity monitoring


sentences: A convolutional neural network highlights mutations relevant to antimicrobial resistance in Mycobacterium tuberculosis


sentences: Fast off-rate CD229 chimeric antigen receptor T cells efficiently target multiple myeloma, spare T cells, and exhibit reduced trogocytosis

labels: bioengineering


sentences: A method to build extended sequence context models of point mutations and indels


sentences: CMash: fast, multi-resolution estimation of k-mer-based Jaccard and containment indices


sentences: Structure-based design of a chemical probe set for the 5-HT5A serotonin receptor


sentences: Processing body dynamics drive non-genetic MEK inhibitors tolerance by fine-tuning KRAS and NRAS translation


sentences: A remote lecture series roadmap to equity, diversity, and inclusion in STEM


sentences: BDNF-dependent modulation of axonal transport is selectively impaired in ALS


sentences: SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice


sentences: The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of the spike A222V mutation

labels: molecular biology


sentences: Omicron: A heavily mutated SARS-CoV-2 variant exhibits stronger binding to ACE2 and potently escape approved COVID-19 therapeutic antibodies


sentences: The High Transmission of SARS-CoV-2 Omicron (B.1.1.529) Variant is Not Only Due to Its hACE2 binding: A Free Energy of Perturbation Study

labels: biochemistry


sentences: Imaging-Guided Bioreactor for De-Epithelialization and Long-Term Cultivation of Ex Vivo Rat Trachea


sentences: Constructing a multiple-layer interactome for SARS-CoV-2 in the context of lung disease: Linking the virus with human genes and co-infecting microbes


sentences: A zebrafish model of COVID-19-associated cytokine storm syndrome reveals differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern.


sentences: The Omicron Variant Increases the Interactions of SARS-CoV-2 Spike Glycoprotein with ACE2


sentences: Receptor binding and escape from Beta antibody responses drive Omicron-B.1.1.529 evolution


sentences: A sarbecovirus found in Russian bats uses human ACE2


sentences: An antibody-escape calculator for mutations to the SARS-CoV-2 receptor-binding domain


sentences: Decoupling SARS-CoV-2 ORF6 localization and interferon antagonism


sentences: Phosphorylation dynamics in a flg22-induced, G-protein dependent network in Arabidopsis thaliana


sentences: Elucidating design principles for engineering cell-derived vesicles to inhibit SARS-CoV-2 infection


sentences: Insertions in the SARS-CoV-2 Spike N-Terminal Domain May Aid COVID-19 Transmission


sentences: Sensory nerves enhance triple-negative breast cancer migration and metastasis via the axon guidance molecule PlexinB3

labels: cancer biology


sentences: Active communities and growth of soil microorganisms are framed by mean annual precipitation in three California annual grasslands


sentences: Gap genes are involved in inviability in hybrids between Drosophila melanogaster and D. santomea


sentences: Cohesin modulates DNA replication to preserve genome integrity


sentences: The genetic origin and architecture of sex determination


sentences: Mutational cascade of SARS-CoV-2 leading to evolution and emergence of omicron variant


sentences: Protein-protein interactions on membrane surfaces analysed using SUPER template pull-downs


sentences: LEXAS: a web application for life science experiment search and suggestion


sentences: CLIPreg: Constructing translational regulatory networks from CLIP-, Ribo- and RNA-seq


sentences: Revised International Staging System (R-ISS) stage-dependent analysis uncovers oncogenes and potential immunotherapeutic targets in multiple myeloma


sentences: Assessment of exposure to Di (2-ethylhexyl) phthalate (DEHP) metabolites and Bisphenol A (BPA) and its importance for the prevention of cardiometabolic diseases

labels: pharmacology and toxicology


sentences: Vertical transmission of tissue microbiota in 	Caenorhabditis elegans

labels: physiology


sentences: Neuron-like function of the nephron central command


sentences: The oscillation of mitotic kinase governs cell cycle latches


sentences: Quantitative and temporal measurement of dynamic autophagy rates


sentences: AP-1 transcription factor network explains diverse patterns of cellular plasticity in melanoma


sentences: Modulation of certainty and valence in cardiac autonomic regulation mediated by high depressive risk


sentences: Analysis of visual processing capabilities and neural coding strategies of a detailed model for laminar cortical microcircuits in mouse V1


sentences: Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis


sentences: Distinct within-host bacterial populations ensure function, colonization and transmission in leaf symbiosis


sentences: Meet me in the middle: median temperatures impact cyanobacteria and photoautotrophy in eruptive Yellowstone hot springs


sentences: Stem cell specific interferon stimulated gene expression is regulated by the formative pluripotency network through IRF1

labels: developmental biology


sentences: Adventive larval parasitoids reconstruct their close association with spotted-wing drosophila in the invaded North American range

labels: ecology


sentences: A single nucleotide variant in the PPARgamma-homolog Eip75B affects fecundity in Drosophila


sentences: A slow dynamic switch regulates processing of microRNA-21


sentences: Decoding the absolute stoichiometric composition and structural plasticity of α-carboxysomes


sentences: Image-based representation of massive spatial transcriptomics datasets


sentences: Engineering RNA viruses with unnatural amino acid to evoke adjustable immune response in mice


sentences: Atypical B cells upregulate co-stimulatory molecules during malaria and secrete antibodies with T follicular helper cell support


sentences: Inhibiting Host Protein Deposition on Urinary Catheters Reduces Urinary Tract Infections


sentences: Loss of Neutralizing Antibody Response to mRNA Vaccination against SARS-CoV-2 Variants: Differing Kinetics and Strong Boosting by Breakthrough Infection


sentences: Live imaging of the Cryptosporidium parvum lifecycle reveals direct development of male and female gametes from type one meronts


sentences: Positional motif analysis reveals the extent of specificity of protein-RNA interactions observed by CLIP


sentences: MYH10 governs adipocyte function and adipogenesis through its interaction with GLUT4


sentences: Differential N-terminal processing of beta and gamma actin in vivo


sentences: Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes


sentences: Cell cycle arrest explained the observed bulk 3D genomic alterations in response to long term heat shock for mammalian cells


sentences: From STRs to SNPs via ddRAD-seq: geographic assignment of confiscated tortoises at reduced costs


sentences: A target capture approach for phylogenomic analyses at multiple evolutionary timescales in rosewoods (Dalbergia spp.) and the legume family (Fabaceae)


sentences: Direct Imaging and Identification of Proteoforms up to 70 kDa from Human Tissue


sentences: Characterization of mutations causing steroid 21-hydroxylase 1 deficiency in Brazilian and Portuguese populations.


sentences: A predictive microfluidic model of human glioblastoma to assess trafficking of blood-brain barrier penetrant nanoparticles


sentences: DALI (Diversity AnaLysis Interface): a novel tool for the integrated analysis of multimodal single cell RNAseq data and immune receptor profiling.


sentences: Magnesium Force Fields for OPC Water with Accurate Solvation, Ion-Binding, and Water-Exchange Properties: Successful Transfer from SPC/E

labels: biophysics


sentences: Collinearity of alpha-helices or beta strands in membrane proteins causes a characteristic peak centred on 4.9 A resolution in diffraction intensity profiles, inducing higher diffraction anisotropy


sentences: Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform


sentences: Microneedle-mediated intratumoral delivery of anti-CTLA-4 promotes cDC1-dependent eradication of oral squamous cell carcinoma with limited irAEs


sentences: Zebrafish xenografts to isolate unique human breast cancer metastatic cell populations


sentences: CaMK1D signaling in AgRP neurons promotes ghrelin-mediated food intake


sentences: Intestinal SEC16B modulates obesity by controlling dietary lipid absorption


sentences: The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells


sentences: Integrin-driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program


sentences: Design of M protein immunogens to elicit broadly reactive antibodies against Streptococcus pyogenes


sentences: A phenotypic rescue approach identifies lineage regionalization defects in a mouse model of DiGeorge syndrome.


sentences: Pre-meiotic pairing of homologous chromosomes during Drosophila male meiosis


sentences: MacroH2A impedes metastatic growth by enforcing a discrete dormancy program in disseminated cancer cells


sentences: Decoupling growth and production by removing the origin of replication from a bacterial chromosome

labels: synthetic biology


sentences: Chemical, molecular, and single cell analysis reveal chondroitin sulfate proteoglycan aberrancy in fibrolamellar carcinoma


sentences: Improvement of beef cattle cows pregnancy rate using an effective dose of Galectin-1


sentences: Horizontal Transfer and Evolution of the Biosynthetic Gene Cluster for Benzoxazinoid


sentences: Experimental evolution under varying sex ratio and nutrient availability modulates male mating success in Drosophila melanogaster


sentences: Significant cross-species gene flow detected in the Tamias quadrivittatus group of North American chipmunks


sentences: A magnetic field prevents alcoholic liver disease by reducing oxidative stress


sentences: Interfacing Spinal Motor Units in Non-Human Primates Identifies a Principal Neural Component for Force Control Constrained by the Size Principle


sentences: Enabling complex fibre geometries using 3D printed axon-mimetic phantoms


sentences: Chloride dynamics determine the optimal distribution of inhibitory synapses to minimise dendritic excitability


sentences: Genetic, environmental and intrinsic determinants of the human antibody epitope repertoire


sentences: Ocean-Warming During Embryogenesis Programs a Lasting Transcriptomic Signature in Fishes


sentences: Aedes koreicus, a vector on the rise: pan-European genetic patterns, mitochondrial and draft genome sequencing

labels: genetics


sentences: AMAW: automated gene annotation for non-model eukaryotic genomes

labels: bioinformatics


sentences: Telomere-Dependent Interleukin-1 Receptor Activation Promotes Immune Suppression in Triple-Negative-Breast Cancer


sentences: The single-cell transcriptional landscape of lung carcinoid tumors


sentences: Complementary role of mathematical modeling in preclinical glioblastoma: differentiating poor drug delivery from drug insensitivity


sentences: A rapid prototyping approach for intensive field courses to build scientific and professional skills

labels: scientific communication and education


sentences: MORPHOLOGICAL DETERMINANTS OF CELL-TO-CELL VARIATIONS IN ACTION POTENTIAL DYNAMICS IN SUBSTANTIA NIGRA DOPAMINERGIC NEURONS


sentences: Arginine-Vasopressin Expressing Neurons in the Murine Suprachiasmatic Nucleus Exhibit a Circadian Rhythm in Network Coherence in vivo


sentences: RNA2Immune: A Manually Curated Database of Experimentally Supported Data Linking Noncoding RNA Regulation to the Immune System

labels: immunology


sentences: A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

labels: genomics


sentences: Cerebellar contributions to a brainwide network for flexible behavior

labels: neuroscience


sentences: Inhibitory neurosteroid reverses the dendritic spine disorder caused by gain-of-function GABAAR epilepsy variants


sentences: Effect sizes of causal variants for gene expression and complex traits differ between populations


sentences: Tsc1 haploinsufficiency leads to Pax2 dysregulation in the developing murine cerebellum


sentences: Identifying protein sites contributing to vaccine escape via statistical comparisons of short-term molecular dynamics simulations


sentences: Metabolic dysregulation induces impaired lymphocyte memory formation during severe SARS-CoV-2 infection


sentences: Chlorine redox chemistry is not rare in biology

labels: microbiology


sentences: Kasturi Haldar, Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism, lipid transport and oxidative stress response


sentences: The cellular characterisation of SARS-CoV-2 spike protein in virus-infected cells using Receptor Binding Domain-binding specific human monoclonal antibodies.


sentences: Characterization of the interaction between SARS-CoV-2 Membrane Protein and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target


sentences: Identification of New In Vivo TonB-FepA Rendezvous Sites


sentences: Structural basis for the peptidoglycan editing activity of YfiH


sentences: CFIm25 regulates human stem cell function independently of its role in mRNA alternative polyadenylation


sentences: A reference genome for the critically endangered woylie, Bettongia penicillata ogilbyi


sentences: Structural basis for topological regulation of Tn3 resolvase


sentences: A proteomic perspective and involvement of cytokines in SARS-CoV-2 infection


sentences: Production of novel Spike truncations in Chinese hamster ovary cells

labels: bioengineering


sentences: Insights on the mutational landscape of the SARS-CoV-2 Omicron variant


sentences: Structural insights into distinct signaling profiles of the μOR activated by diverse agonists


sentences: The structural basis of mRNA recognition and binding by eukaryotic pseudouridine synthase PUS1


sentences: An effective workshop on How to be an Effective Mentor for Underrepresented STEM Trainees


sentences: No evidence of fetal defects or anti-syncytin-1 antibody induction following COVID-19 mRNA vaccination


sentences: Bacterial and fungal communities experience rapid succession during the first year following a wildfire in a California chaparral.


sentences: Testosterone promotes Coxsackievirus B3 pathogenesis in an oral inoculation mouse model


sentences: Intranasal immunization with a vaccinia virus vaccine vector expressing pre-fusion stabilized SARS-CoV-2 spike fully protected mice against lethal challenge with the heavily mutated mouse-adapted SARS2-N501YMA30 strain of SARS-CoV-2


sentences: mCherry contains a fluorescent protein isoform that interferes with its reporter function

labels: molecular biology


sentences: Standard Intein Gene Expression Ramps (SIGER) for protein-independent expression control


sentences: Rational engineering of industrial S. cerevisiae: towards xylitol production from sugarcane bagasse


sentences: Ribosome changes elicit non-canonical translation for chemosurvival in G0 leukemic cells


sentences: iMUT-seq: high-resolution mapping of DSB mutational landscapes reveals new insights into the mutagenic mechanisms of DSB repair


sentences: A novel multi-functional role for the MCM8/9 helicase complex in maintaining fork integrity during replication stress

labels: cell biology


sentences: The p97-UBXD8 complex modulates ER-Mitochondria contact sites by modulating membrane lipid saturation and composition


sentences: Genomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave (Sicily, Italy)


sentences: Transcriptomic modulation in response to an intoxication with deltamethrin in Triatoma infestans, vector of Chagas disease


sentences: Biophysical Characterisation of Human LincRNA-p21 Sense and Antisense Alu Inverted Repeats

labels: biochemistry


sentences: Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation


sentences: Genomic insertion locus and Cas9 expression in the germline affect CRISPR/Cas9-based gene drive performance in the yellow fever mosquito Aedes aegypti


sentences: A dynamic model of the ABA Signaling pathway with its core components: translation rate of PP2C determines the kinetics of ABA-induced gene expression

labels: systems biology


sentences: Over-expression of wild-type ACVR1 in fibrodysplasia ossificans progressiva mice rescues perinatal lethality and inhibits heterotopic ossification


sentences: The influence of new SARS-CoV-2 variant Omicron (B.1.1.529) on vaccine efficacy, its correlation to Delta Variants: a computational approach


sentences: Proteogenomic analysis of aneuploidy reveals divergent types of gene expression regulation across cellular pathways


sentences: Molecular mechanism of claudin-15 strand flexibility


sentences: Glioblastoma embryonic-like stem cells exhibit immune-evasive phenotype

labels: cancer biology


sentences: Root membrane ubiquitinome under short-term osmotic stress

labels: plant biology


sentences: Pre-determined diversity in resistant fates emerges from homogenous cells after anti-cancer drug treatment


sentences: Analyses of the Autism-associated Neuroligin-3 R451C Mutation in Human Neurons Reveals a Gain-of-Function Synaptic Mechanism


sentences: Mechanical ventilation affects the microecology of the rat respiratory tract


sentences: Wide Diversity of Recombinant Noroviruses Circulating in Spain, 2016 to 2020


sentences: Quantitative Mapping of Keratin Networks in 3D


sentences: C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100A8 and S100A9


sentences: STRAIGHT-IN: A platform for high-throughput targeting of large DNA payloads into human pluripotent stem cells


sentences: RoPod, a customizable toolkit for non-invasive root imaging, reveals cell type-specific dynamics of plant autophagy


sentences: SWR1C catalyzes H2A.Z deposition by coupling ATPase activity to the nucleosome acidic patch


sentences: I-M-150847, a novel GLP-1 and GIP receptor dual agonist, reduces body weight gain and improves glycemic control in the rodent model of type 2 diabetes and obesity.

labels: physiology


sentences: XopQ induced stromule formation in Nicotiana benthamiana is causally linked to ETI signaling and depends on ADR1 and NRG1


sentences: Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency


sentences: SARS-CoV-2 variants of concern are dependent on IFITM2 for efficient replication in human lung cells


sentences: TSG101 Associates with PARP1 and is Essential for PARylation and DNA Damage-induced NF-κB Activation


sentences: Microdomain protein Nce102 is a local sensor of plasma membrane sphingolipid balance


sentences: Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its pathological conformational conversion


sentences: Regulation of protein complex partners as a compensatory mechanism in aneuploid tumors


sentences: Heterogeneity of the GFP fitness landscape and data-driven protein design


sentences: The Spatial Reach of Neuronal Coherence and Spike-field Coupling across the Human Neocortex


sentences: Endogenous Syngap1 Alpha Splice Forms Promote Cognitive Function and Seizure Protection


sentences: Vascular proteome responses precede organ dysfunction in sepsis


sentences: Rapid and robust directed differentiation of mouse epiblast stem cells into definitive endoderm and forebrain organoids

labels: developmental biology


sentences: Single cell quantification of ribosome occupancy in early mouse development


sentences: Game Of Theories: An Agent-Based Model Of How Variation In Contest Cost-Benefits Determines The Evolution Of Contest Resolution Rules

labels: animal behavior and cognition


sentences: The consequence of fiber orientation downsampling on the computation of white matter tract-related deformation


sentences: Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells


sentences: HSV-1 and influenza infection induce linear and circular splicing of the long NEAT1 isoform


sentences: Large Scale Discovery of Microbial Fibrillar Adhesins and Identification of Novel Adhesive Domain Families


sentences: Semi-automated computational assessment of cancer organoid viability using rapid live-cell microscopy


sentences: What's past is past, mostly: Brassicaceae host plants mask the feedback from the previous year's soil history on bacterial communities, except when the Brassicaceae hosts experience drought


sentences: Small transcriptional differences lead to distinct NF-κB dynamics in quasi-identical cells


sentences: Using coexpression to explore cell-type diversity with the fcoex package


sentences: Transparent and Conformal Microcoil Arrays for Spatially Selective Neuronal Activation


sentences: Neural Oscillatory Characteristics of Feedback Associated Activity in Globus Pallidus Interna


sentences: Intermittent brain network reconfigurations and the resistance to social media influence


sentences: Lysophosphatidylcholine induces heat pain hypersensitivity in obese mice fed with a high-fat diet through activation of peripheral Acid-Sensing Ion Channel 3


sentences: Early detection of sublexical and lexical processing in beginning readers: evidence from Steady-State Visual Evoked Potentials (SSVEPs)


sentences: Nonlinear dynamics in auditory cortical activity reveal the neural basis of perceptual warping in speech categorization


sentences: Non-monotonic effects of GABAergic synaptic inputs on neuronal firing


sentences: Altricial bird early-stage embryos express the molecular "machinery" to respond to maternal thyroid hormone cues


sentences: Spatiotemporal transcriptomics reveals pathogenesis of viral myocarditis


sentences: Attentive deep learning-based tumor-only somatic mutation classifier achieves high accuracy agnostic of tissue type and capture kit.


sentences: solPredict: Antibody apparent solubility prediction from sequence by transfer learning


sentences: AttentionSiteDTI: Attention Based Model for Predicting Drug-Target Interaction Using 3D Structure of Protein Binding Sites


sentences: Predicting the Toxicity of Druggable Proteins to Human Tissues


sentences: Consequence of adjustments for demographic or clinical covariates and a recommended solution in genome-wide association studies


sentences: Revealing a hidden intermediate of rotatory catalysis with X-ray crystallography and Molecular simulations

labels: biophysics


sentences: Differential Histone-DNA Interactions Dictate Nucleosome Recognition of the Pioneer Transcription Factor Sox


sentences: Scalable Adaptive Protein Ensemble Refinement Integrating Flexible Fitting


sentences: High genetic diversity of bivalve transmissible neoplasia in the blue mussel Mytilus trossulus Gould from the subarctic Sea of Okhotsk


sentences: Compromised CDK12 activity causes dependency on the non-essential spliceosome components


sentences: Physiological activation of the nephron central command drives endogenous kidney tissue regeneration


sentences: GOLDEN TANGERINE TOMATO ROOTS SHOW INCREASED ACCUMULATION OF ACYCLIC CAROTENOIDS, LESS ABSCISIC ACID, DROUGHT SENSITIVITY, AND IMPAIRED ENDOMYCORRHIZAL COLONIZATION


sentences: Recut: a Concurrent Framework for Sparse Reconstruction of Neuronal Morphology


sentences: Early stage differentiation of glia in human and mice.


sentences: Reconfigurations in brain networks upon awakening from slow wave sleep: Interventions and implications in neural communication


sentences: High-Speed Low-Light In Vivo Two-Photon Voltage Imaging of Large Neuronal Populations


sentences: Linker histone H1FOO is required for bovine preimplantation development by regulating lineage specification and nucleosome assembly


sentences: Severe disturbance overflows the stabilizing buffer of variable biotic interactions

labels: ecology


sentences: Trailing-edge zombie forests can increase population persistence in the face of climate change


sentences: BSImp: imputing partially observed methylation patterns for evaluating methylation heterogeneity

labels: bioinformatics


sentences: Structural mechanism for bi-directional actin crosslinking by T-plastin


sentences: The eukaryotic translation initiation factor eIF4E reprogrammes the splicing machinery anddrives alternative splicing


sentences: Novel Fusarium Wilt Resistance Genes Uncovered in the Wild Progenitors and Heirloom Cultivars of Strawberry


sentences: Structural basis for substrate recognition, ligation and activation by a hyperactive Asn peptide ligase from Viola yedoensis


sentences: Allosteric regulation of the proteasomes catalytic sites by the proteasome activator PA28gamma/REGgamma


sentences: MeasureIce: Accessible on-the-fly measurement of ice thickness in cryo-electron microscopy


sentences: Long Noncoding RNA RROL Provides Chromatin Scaffold for MYC-WDR82 Interaction to Impact Lipid Metabolism and Tumor Cell Growth in Multiple Myeloma


sentences: EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma


sentences: Stress-impaired reward pathway promotes distinct feeding behavior patterns


sentences: Neurexins in serotonergic neurons regulate serotonin transmission and complex mouse behaviors


sentences: Role of anterior insula cortex in context-induced relapse of nicotine-seeking


sentences: Drosophila gustatory projections are segregated by taste modality and connectivity


sentences: Drosulfakinin signaling modulates female sexual receptivity in Drosophila


sentences: A striatal circuit balances learned fear in the presence and absence of sensory cues


sentences: Escape Steering by Cholecystokinin Peptidergic Signaling


sentences: Manganese is a Physiologically Relevant TORC1 Activator in Yeast and Mammals.


sentences: DRP1 regulates endoplasmic reticulum sheets to control mitochondrial DNA replication and segregation


sentences: Inference for epidemic models with time varying infection rates: tracking the dynamics of oak processionary moth in the UK


sentences: Macroevolutionary dynamics of climatic niche space

labels: evolutionary biology


sentences: Photosynthesis and antioxidant metabolism modulate the low-temperature resistance of seed germination in maize

labels: genomics


sentences: The SPEECHLESS-induced stomatal increase is required for the salt tolerance of oil palm


sentences: Novel piece of the puzzle: ALI1 is required for oxo-C14-HSL priming in Arabidopsis


sentences: Pharmacologic analysis of non-synonymous coding 5-HT2A SNPs reveals alterations psychedelic drug potencies and efficacies

labels: neuroscience


sentences: Antagonism of D1, but not D2, dopamine receptors inhibits cued sucrose seeking by decreasing arousal


sentences: Deficiency in endocannabinoid synthase DAGLB contributes to Parkinson's disease and dopaminergic neuron dysfunction


sentences: Novel and known transcriptional targets of ALS/FTD protein TDP-43: Meta-analysis and interactive graphical databases


sentences: Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content related to inflammation and recovery processes


sentences: Increased context adjustment is associated with auditory sensitivities but not with autistic traits


sentences: The double-edged role of nitric oxide drives predictable microbial community organization according to the microenvironment

labels: microbiology


sentences: Engineering efficient termination of bacteriophage T7 RNA polymerase transcription


sentences: A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia


sentences: Divalent metal ions boost effect of nucleic acids delivered by cell-penetrating peptides


sentences: Estimating abundance of a recovering transboundary brown bear population with capture-recapture models


sentences: Differential effects of soil-based agricultural diversification on arthropods and crop yield


sentences: Co-evolution of Leptospira and Tenrecidae (Afrotheria) on Madagascar


sentences: Spodoptera littoralis genome mining brings insights on the dynamic of expansion of gustatory receptors in polyphagous noctuidae


sentences: Colonic Oxygen Microbubbles Augment Systemic Oxygenation and CO2 Removal in a Porcine Smoke Inhalation Model of Severe Hypoxia

labels: bioengineering


sentences: DISEASES 2.0: a weekly updated database of disease-gene associations from text mining and data integration


sentences: Coalescent tree recording with selection for fast forward-in-time simulations


sentences: Investigating the conformational dynamics of Zika virus NS4B protein


sentences: Identification and Validation of Novel Microtubule Suppressors with an Imidazopyridine Scaffold through Structure Based Virtual Screening and Docking.


sentences: Chronic AMPK inactivation slows SHH medulloblastoma progression by inhibiting mTORC1 signaling and depleting tumor stem cell populations


sentences: Ca2+ oscillations, waves, and networks in islets from human donors with and without type 2 diabetes


sentences: Phosphate-induced resistance to pathogen infection in Arabidopsis


sentences: Can pyrethroid-piperonyl butoxide (PBO) nets reduce the efficacy of indoor residual spraying with pirimiphos-methyl against pyrethroid-resistant malaria vectors?

labels: zoology


sentences: Early neural activity changes associated with visual conscious perception


sentences: Directional Tuning of Phase Precession Properties in the Hippocampus


sentences: Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD


sentences: In-depth characterization of the serum antibody epitope repertoire in inflammatory bowel disease using phage-displayed immunoprecipitation sequencing

labels: immunology


sentences: Quantitative Structural Analysis of Influenza Virus by Cryo-electron Tomography and Convolutional Neural Networks


sentences: Noncanonical structural requirements of neurofibromin SUMOylation reveal a folding-deficiency of several pathogenic mutants

labels: molecular biology


sentences: Wanted not, wasted not: Searching for non-target taxa in environmental DNA metabarcoding by-catch


sentences: Life history adaptations to fluctuating environments: Combined effects of demographic buffering and lability of vital rates


sentences: Micro- and macroevolutionary change of colony-level traits in bryozoans


sentences: Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen

labels: genetics


sentences: Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance


sentences: A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples


sentences: Immobilization of C. elegans on cultivation plates by thermoelectric cooling for high-throughput subcellular-resolution microscopy


sentences: Empowering Engineered Muscle in Biohybrid Pump by Extending Connexin 43 Duration with Reduced Graphene Oxides


sentences: BioImageIT: Open-source framework for integration of image data-management with analysis


sentences: Canalized morphogenesis driven by inherited tissue asymmetries in Hydra regeneration


sentences: Kinetic characteristics of transcriptional bursting in a complex gene model with cyclic promoter structure

labels: systems biology


sentences: Task Demands Change Motion Information Coding in Area MT of the Macaque


sentences: Distribution map of peristaltic waves in the chicken embryonic gut reveals importance of ENS and inter-region cross talks along the gut axis


sentences: Harnessing gene-gene interactions via an RNA-Sequencing network analysis framework improves precision medicine prediction in rheumatoid arthritis


sentences: The Presence of the Temporal Horn Exacerbates the Vulnerability of Hippocampus during Head Impacts


sentences: A mosaic bulk-solvent model improves density maps and the fit between model and data


sentences: Predicting the Functional Impact of KCNQ1 Variants with Artificial Neural Networks


sentences: Glucose dynamics during ozone exposure measured using radiotelemetry: Stress drivers and human concordance

labels: pharmacology and toxicology


sentences: A fungal plant pathogen overcomes conserved broad-spectrum disease resistance by rapid gene loss

labels: plant biology


sentences: Time-dependent memory and individual variation in Arctic brown bears (Ursus arctos)


sentences: Minimal cross-over between mutations associated with Omicron variant of SARS-CoV-2 and CD8+ T cell epitopes identified in COVID-19 convalescent individuals


sentences: Plant-based expression of SARS-CoV-2 antigens for use in an oral vaccine


sentences: The UV RESISTANCE LOCUS 8-Mediated UV-B Response Is Required Alongside CRYPTOCHROME1 For Plant Survival Under Sunlight In The Field


sentences: Predictive profiling of SARS-CoV-2 variants by deep mutational learning

labels: synthetic biology


sentences: Simultaneous analysis of antigen-specific B and T cells after SARS-CoV-2 infection and vaccination


sentences: B.1.1.529 escapes the majority of SARS-CoV-2 neutralizing antibodies of diverse epitopes


sentences: Combinatorial mRNA vaccination enhances protection against SARS-CoV-2 delta variant


sentences: Orally administered epeleuton inhibits SARS-CoV-2 viral load, replication and pathology in the Syrian Hamster model


sentences: Deep Mutational Engineering of broadly-neutralizing and picomolar affinity nanobodies to accommodate SARS-CoV-1 & 2 antigenic polymorphism

labels: biochemistry


sentences: Mutations in the spike RBD of SARS-CoV-2 omicron variant may increase infectivity without dramatically altering the efficacy of current multi-dosage vaccinations


sentences: A Graph Convolutional Network-based screening strategy for rapid identification of SARS-CoV-2 cell-entry inhibitors


sentences: Structural Insights of SARS-CoV-2 Spike Protein from Delta and Omicron Variants

labels: biophysics


sentences: Atypus karschi Dönitz, 1887 (Araneae: Atypidae): an Asian purse-web spider established in Pennsylvania, USA


sentences: Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responses


sentences: A novel bacterial protease inhibitor adjuvant in RBD-based COVID-19 vaccine formulations increases neutralizing antibodies, specific germinal center B cells and confers protection against SARS-CoV-2 infection.


sentences: A co-opted endogenous retroviral envelope promotes cell survival by controlling SLC31A1/CTR1-mediated copper transport and homeostasis


sentences: Preliminary Characterization of Phage-like Particles from the Male-Killing Mollicute Spiroplasma poulsonii (an Endosymbiont of Drosophila)


sentences: Nitrogen metabolism in Pseudomonas putida: functional analysis using random barcode transposon sequencing


sentences: Biogenesis of a bacterial metabolosome for propanediol utilization


sentences: Nanotrap Particles Improve Nanopore Sequencing of SARS-CoV-2 and Other Respiratory Viruses


sentences: Rec8 cohesin-mediated loop-axis chromatin architecture is required for meiotic recombination

labels: cell biology


sentences: Acute oral toxicity of zinc phosphide: an assessment for wild house mice in Australia

labels: ecology


sentences: Linked-read whole-genome sequencing resolves common and private structural variants in multiple myeloma


sentences: Fast in-vitro screening of FLT3-ITD inhibitors using silkworm-baculovirus protein expression system


sentences: Whole genome resequencing and comparative genome analysis of three Puccinia striiformis f. sp. tritici pathotypes prevalent in India

labels: bioinformatics


sentences: SARS-CoV-2 Omicron Spike Glycoprotein Receptor Binding Domain Exhibits Super-Binder Ability with ACE2 but not Convalescent Monoclonal Antibody


sentences: The Landscape-Based Protein Stability Analysis and Network Modeling of Multiple Conformational States of the SARS-CoV-2 Spike D614 Mutant: Conformational Plasticity and Frustration-Driven Allostery as Energetic Drivers of Highly Transmissible Spike Variant


sentences: eIF5B and eIF1A remodel human translation initiation complexes to mediate ribosomal subunit joining


sentences: Nuclear NAD+ homeostasis is essential for naive and chemoresistant BRCA1/2-deficient tumor survival

labels: cancer biology


sentences: Programmable in vivo CRISPR activation   elucidates the oncogenic and immunosuppressive role of MYC in lung adenocarcinoma


sentences: Effect of growth forms of bamboo on the mycorrhizal and fluorescent pseudomonas population


sentences: The Role of Mentoring in Promoting Diversity, Equity, and Inclusion in STEM Education and Research

labels: scientific communication and education


sentences: Strain variation in Clostridioides difficile toxin activity associated with genomic variation at both PaLoc and non-PaLoc loci

labels: microbiology


sentences: Variable oxygen environments and DNMT2 determine the DNA cytosine epigenetic landscape of Plasmodium falciparum


sentences: Microbiome Analysis of Gut Bacterial Communities of Healthy and Diseased Malaysian Mahseer (Tor tambroides)


sentences: A small molecule reveals role of insulin receptor-insulin like growth factor-1 receptor heterodimers


sentences: Toxoplasma ERK7 defends the apical complex from premature degradation


sentences: Hierarchical length and sequence preferences establish a single major piRNA 3'-end

labels: developmental biology


sentences: Transcriptional response in a sepsis mouse model reflects transcriptional response in sepsis patients

labels: genomics


sentences: Ongoing transposition in cell culture reveals the phylogeny of diverse Drosophila S2 sub-lines.


sentences: Long read sequencing reveals sequential complex rearrangements driven by Hepatitis B virus integration


sentences: LitRev: A data driven method for quick literature review from PubMed


sentences: Protein Organization with Manifold Exploration and Spectral Clustering


sentences: CXCL8/CXCR2 signaling mediates bone marrow fibrosis and represents a therapeutic target in myelofibrosis


sentences: Quantitative Action Spectroscopy Reveals ARPE-19 Sensitivity to Long-Wave Ultraviolet Radiation at 350 nm and 380 nm


sentences: Geographic variation in larval cold tolerance and exposure across the invasion front of a widely established forest insect

labels: physiology


sentences: Rapamycin induces autophagy and increases heat tolerance in Drosophila melanogaster


sentences: The need for unrealistic experiments in global change biology


sentences: Volatile-mediated signaling induces resistance of barley against infection with the biotrophic fungus Blumeria graminis f.sp. hordei


sentences: Rational domestication of a plant-based recombinant expression system expands its biosynthetic range.


sentences: Development and validation of inducible protein degradation and quantitative phosphoproteomics to identify kinase-substrate relationships.


sentences: Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy through Akt-mTOR Signaling

labels: neuroscience


sentences: Trapping of Nicotinic Acetylcholine Receptor Ligands Assayed by in vitro Cellular Studies and in vivo PET Imaging


sentences: SV2A-Syt1 interaction controls surface nanoclustering and access to recycling synaptic vesicles


sentences: CD4+ and CD8+ regulatory T cells characterization in the rat using a unique transgenic Foxp3-EGFP model.

labels: immunology


sentences: The polyanionic drug suramin neutralizes histones and prevents endotheliopathy


sentences: Integrated computational and in vivo models reveal Key Insights into Macrophage Be-havior during bone healing


sentences: Discovery of a new species of trichomonasvirus in the human parasite Trichomonas vaginalis using transcriptome mining


sentences: HBV enveloped particle secretion is positively regulated by GRP78 through direct interaction with preS1


sentences: Transcriptome-wide identification of coding and noncoding RNA-binding proteins defines the comprehensive RNA interactome of Leishmania mexicana


sentences: A novel Alex3/Gαq protein complex regulating mitochondrial dynamics, dendritic complexity, and neuronal survival


sentences: The luminal AAA+ ATPase torsinA mediates distinct mechanisms of nuclear-cytoplasmic communication by adopting different functional assembly states.


sentences: It ain't what you do, it's what drives why you do it: how the basis of growers' decision making affects the effectiveness of disease control


sentences: Estimating real snakebite incidence in Colombia by using mathematical modelling and statistical inference.


sentences: Trade-offs among plant reproductive traits determine interactions with floral visitors


sentences: The Gulf Coast tick, Amblyomma maculatum (Ixodida: Ixodidae) and spotted fever group Rickettsia in the highly urbanized northeastern US


sentences: Prior selfing occur in larger flowers in a mixed mating species with delayed selfing


sentences: Lessons on fruiting body morphogenesis from genomes and transcriptomes of Agaricomycetes

labels: evolutionary biology


sentences: The price of defence: toxins, visual signals and oxidative state in an aposematic butterfly


sentences: Polynomial Mendelian Randomization reveals widespread non-linear causal effects in the UK Biobank

labels: genetics


sentences: Deciphering the genetic links between NAFLD and co-occurring conditions using a liver gene regulatory network


sentences: Plasticity across levels: relating epigenomic, transcriptomic, and phenotypic responses to osmotic stress in a halotolerant microalga


sentences: Temporal response characterization across individual multiomics profiles of prediabetic and diabetic subjects


sentences: Ancient DNA from a 2,700-year-old goitered gazelle (Gazella subgutturosa) confirms gazelle hunting in Iron Age Central Asia


sentences: Accurate measurement of microsatellite length by disrupting its tandem repeat structure


sentences: A mathematical model for cell-induced gel contraction incorporating osmotic effects

labels: bioengineering


sentences: Label-free imaging to track reprogramming of human somatic cells


sentences: An engineered nanocomplex with Photodynamic and Photothermal synergistic properties for cancer treatment


sentences: Evolution of tunnels in alpha/beta-hydrolase fold proteins - what can we learn from studying epoxide hydrolases?


sentences: InterPepScore: A Deep Learning Score for Improving the FlexPepDock Refinement Protocol


sentences: Efficient pre-processing of Single-cell ATAC-seq data


sentences: Improved Transcriptome Assembly Using a Hybrid of Long and Short Reads with StringTie


sentences: DISA tool: discriminative and informative subspace assessment with categorical and numerical outcomes


sentences: DeepRank-GNN: A Graph Neural Network Framework to Learn Patterns in Protein-Protein Interfaces


sentences: The role of surface adhesion on the macroscopic wrinkling of biofilms


sentences: Ion Transport, Selectivity, and Electronic Polarization in Fluoride Channels


sentences: Lipid droplets 3D full measurement by holographic in-flow tomography


sentences: The Effect of Ligands and Transducers on the Neurotensin Recep-tor 1 (NTS1) Conformational Ensemble


sentences: HDfleX: Software for flexible high structural resolution of hydrogen/deuterium-exchange mass spectrometry data


sentences: WILD-seq: Clonal deconvolution of transcriptomic signatures of sensitivity and resistance to cancer therapeutics in vivo.


sentences: Minor intron splicing efficiency increases with the development of lethal prostate cancer


sentences: Labyrinthin: A distinct pan-adenocarcinoma diagnostic and immunotherapeutic tumor specific antigen


sentences: Single-cell meta-analysis of cigarette smoking lung atlas


sentences: A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader

labels: pharmacology and toxicology


sentences: Functional modulation of PTH1R activation and signalling by RAMP2


sentences: Comparing Brain Asymmetries Independently of Brain Size


sentences: Mapping of the autophagosomal degradome identifies IL-7Rα as key cargo in proliferating CD4+ T-cells


sentences: Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity


sentences: Human cellular homeostasis buffers trans-acting translational effects of heterologous gene expression with very different codon usage bias


sentences: Fitness of breeders in social Damaraland mole-rats is independent of group size


sentences: Exact breakpoints of In(1)wm4 rearrangement


sentences: CRISPR knockouts of pmela and pmelb engineered a golden tilapia by regulating relative pigment cell abundance


sentences: Host immune responses to enzootic and invasive pathogen lineages vary in magnitude, timing, and efficacy


sentences: A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes


sentences: Genome-wide identification and analyses of tomato (Solanum lycopersicum L.) high-affinity nitrate transporter 2 (NRT2) family genes and their responses to drought and salinity


sentences: Simultaneous quantification of ankle, muscle, and tendon impedance in humans


sentences: Induced fit with replica exchange improves protein complex structure prediction


sentences: scMARK an 'MNIST' like benchmark to evaluate and optimize models for unifying scRNA data


sentences: Differential Compositional Variation FeatureSelection: A Machine Learning Framework with LogRatios for Compositional Metagenomic Data


sentences: Skopi: a simulation package for diffractive imaging of noncrystalline biomolecules


sentences: NITROGEN LIMITATION ADAPTATION functions as a negative regulator of Arabidopsis immunity

labels: plant biology


sentences: Improving Lab Culture Through Self-Assessment: A Case Study


sentences: The channel capacity of multilevel linguistic features constrains speech comprehension


sentences: miR-124 regulates Notch and NeuroD1 to mediate transition states of neuronal development


sentences: The intrinsic spatiotemporal organization of the human brain - A multi-dimensional functional network atlas


sentences: Shared mechanisms of auditory and non-auditory vocal learning in the songbird brain


sentences: Preserved representations and decodability of diverse cognitive functions across the cortex, cerebellum, and subcortex


sentences: Boosting serotonin increases information gathering by reducing subjective cognitive costs


sentences: Age- and sex-related differences in baboon (Papio anubis) gray matter covariation


sentences: Primary infection by E. multilocularis induces distinct patterns of crosstalk between hepatic regulatory T and natural killer T cells in mice


sentences: Modulation of the Drosophila Transcriptome by Developmental Exposure to Alcohol


sentences: An epitope specific patient-derived LGI1-autoantibody enhances neuronal excitability by modulating the Kv1.1 channel.


sentences: 4-phenylbutyrate restored GABA uptake and reduced seizures in SLC6A1 variants-mediated disorders


sentences: Aneuploidy influences the gene expression profiles in Saccharomyces pastorianus group I and II strains during fermentation.


sentences: Fission of megamitochondria into multiple smaller well-defined mitochondria in the ageing zebrafish retina


sentences: Manipulating the microbiome alters regenerative outcomes in Xenopus laevis tadpoles vis lipopolysaccharide signalling


sentences: A chemically defined biomimetic surface for enhanced isolation efficiency of high-quality human mesenchymal stromal cells under xeno-/serum-free conditions


sentences: OSBP-mediated cholesterol transfer determines epithelial polarity and associated cargo secretion


sentences: No support for a meiosis suppressor in Daphnia pulex: Comparison of linkage maps reveals normal recombination in males of obligate parthenogenetic lineages.


sentences: Visual Interpretation of the Meaning of kcat/KM in Enzyme Kinetics

labels: biochemistry


sentences: Predicting genes associated with RNA methylation pathways using machine learning


sentences: Influence of effective polarization on ion and water interactions within a biomimetic nanopore

labels: biophysics


sentences: Lipidomic analysis of adipose-derived extracellular vesicles reveals their potential as lipid mediators of obesity-associated metabolic complications


sentences: Effects of sub-lethal single, simultaneous, and sequential abiotic stresses on phenotypic traits of Arabidopsis thaliana


sentences: Tomato SlBES1.8 influences leaf morphogenesis by mediating gibberellin metabolism and signaling


sentences: Iron treatment induces defense responses and disease resistance against Magnaporthe oryzae in rice


sentences: Probing the segregation of evoked and spontaneous neurotransmission via photobleaching and recovery of a fluorescent glutamate sensor


sentences: Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings


sentences: Speech Sound Discrimination by Mongolian Gerbils


sentences: Systematic analysis of C. elegans embryo behavior reveals a stereotyped developmental progression and a rhythmic pattern of behavioral quiescence


sentences: Targeting targeted memory reactivation: characteristics of cued reactivation in sleep


sentences: Leaders are made: Learning acquisition of consistent leader-follower relationships depends on implicit haptic interactions.


sentences: Multi-taskLearning and Ensemble Approach to Predict Cognitive Scores for Patients with Alzheimer's Disease


sentences: Seeing the future: predictive control in neural models of ocular accommodation


sentences: Rewarded extinction increases amygdalar connectivity and stabilizes long-term memory traces in the vmPFC


sentences: Engineered biological neural networks on high density CMOS micro electrode arrays


sentences: Integration of visual motion and pursuit signals in areas V3A and V6+ across cortical depth using 9.4T fMRI


sentences: Performance During Whole Body Reaching Movements Is Impaired In Hypergravity While Preserved In Microgravity


sentences: People with nicotine dependence use-disorder exhibit more prefrontal activity during preparatory control but reduced anterior cingulate activity during reactive control


sentences: D-amphetamine maintenance therapy reduces cocaine use in female rats


sentences: Extracellular release of two peptidases dominates generation of the trypanosome quorum-sensing signal


sentences: A conserved viral amphipathic helix governs the replication site-specific membrane association


sentences: BrnQ-type Branched-chain Amino Acid Transporters Influence Bacillus anthracis Growth and Virulence


sentences: Salmonella Typhimurium induces NAIP/NLRC4- and NLRP3/ASC-independent, caspase-1/4-dependent inflammasome activation in human intestinal epithelial cells


sentences: Cell cycle-dependent recruitment of FtsN to the divisome in Escherichia coli


sentences: Colorimetric and fluorescent TRAP assays for visualising and quantifying fish osteoclast activity

labels: cell biology


sentences: North and East African mitochondrial genetic variation needs further characterization towards precision medicine


sentences: A single-cell genomic strategy for alternative transcript start sites identification


sentences: DeepPlnc: Discovering plant lncRNAs through multimodal deep learning on sequential data

labels: bioinformatics


sentences: Identification of functional residues using machine learning provides insights into the evolution of odorant receptor gene families in solitary and social insects


sentences: Isolation and characterization of fucosylated extracellular vesicles based on a novel GlyExo-Capture technique

labels: cancer biology


sentences: Quantification of microbial robustness

labels: synthetic biology


sentences: Identification of genome-wide distribution of cyanobacterial group 2 sigma factor SigE accountable for its regulon

labels: molecular biology


sentences: A nanobody-based toolset to monitor and modify the mitochondrial GTPase Miro1


sentences: Radiation Exposure Determination in a Secure, Cloud-based Online Environment


sentences: Promising or problematic? Perceptions of active learning from STEM students with ADHD and specific learning disabilities

labels: scientific communication and education


sentences: Towards Biophysical Markers of Depression Vulnerability


sentences: Whole-brain optical access in small adult vertebrates with two- and three-photon microscopy


sentences: Using marine cargo traffic to identify countries in Africa with greatest risk of invasion by Anopheles stephensi

labels: ecology


sentences: Using ultraconserved elements to reconstruct the termite tree of life


sentences: Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window


sentences: New insights into colorectal cancer liver metastasis carcinogenesis and its effect with moxibustion


sentences: Rule-based and stimulus-based cues bias auditory decisions via different computational and physiological mechanisms


sentences: Analysis of single-cell RNA-sequencing data to identify quiescent and proliferating neural cell populations in Glioblastoma


sentences: Direct and latent effects of ocean acidification on the transition of a sea urchin from planktonic larva to benthic juvenile

labels: developmental biology


sentences: Digital restoration of the pectoral girdles of two Early Cretaceous birds, and implications for early flight evolution


sentences: Urine proteomics as a non-invasive approach to monitor exertional rhabdomyolysis during military training


sentences: Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers


sentences: RAS mutation patterns arise from tissue-specific responses to distinct oncogenic signaling


sentences: Cognitive experience alters cortical involvement in navigation decisions

labels: neuroscience


sentences: Commanding or being a simple intermediary: how does it affect moral behavior and related brain mechanisms?


sentences: Detection of Motor-Evoked Potentials Below the Noise Floor: Rethinking the Motor Threshold


sentences: Benchmarking GE-BOLD, SE-BOLD, and SS-SI-VASO sequences for depth-dependent separation of feedforward and feedback signals in high-field MRI


sentences: Neuronal activity-driven oligodendrogenesis in selected brain regions is required for episodic memories


sentences: Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis


sentences: Robust regulatory architecture of pan-neuronal gene expression


sentences: Disrupted-in-Schizophrenia-1 is required for proper pyramidal cell-interneuron communication and network dynamics in the prefrontal cortex.


sentences: Behavioural consequences of Setd1a haploinsufficiency in mice: evidence for heightened emotional reactivity and impaired sensorimotor gating


sentences: Active neural coordination of motor behaviors with internal states


sentences: Flexibility in the social structure of male chimpanzees (Pan troglodytes schweinfurthii) in the Budongo Forest, Uganda

labels: animal behavior and cognition


sentences: The minor spliceosome offers a therapeutically viable target for the treatment of a broad spectrum of cancers


sentences: Boron Supply Restores Aluminum-Blocked Auxin Transport by Modulation PIN2 Trafficking in the Arabidopsis Roots

labels: physiology


sentences: Dopamine D2Rs Coordinate Cue-Evoked Changes in Striatal Acetylcholine Levels


sentences: Protein interaction network analysis reveals growth conditions-specific crosstalk between chromosomal DNA replication and other cellular processes in E. coli

labels: microbiology


sentences: A short prokaryotic argonaute cooperates with membrane effector to confer antiviral defense


sentences: Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions


sentences: Nanoscale architecture and coordination of actin cores within the sealing zone of human osteoclasts


sentences: SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta


sentences: Mechanisms underlying melanoma invasion as a consequence of MLK3 loss


sentences: De novo apical domain formation inside the Drosophila adult midgut epithelium


sentences: Energetic determinants of the Par-3 interaction with the Par complex


sentences: Syntaxin 5 determines Weibel-Palade body size and Von Willebrand factor secretion by controlling Golgi architecture


sentences: A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues


sentences: Candidatus Nitrosopolaris, a genus of putative ammonia-oxidizing archaea with a polar/alpine distribution


sentences: Sub-communities of the vaginal ecosystem in pregnant and non-pregnant women.


sentences: Macrophage cell lines and murine infection by Salmonella Typhi L-form bacteria


sentences: Timing of exposure is critical in a highly sensitive model of SARS-CoV-2 transmission


sentences: Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2


sentences: Programmed knockout mutation of liver fluke granulin, Ov-grn-1, attenuates virulence and impedes malignant transformation during chronic opisthorchiasis


sentences: Multiple ETS Factors Participate in the Transcriptional Control of TERT Mutant Promoter in Thyroid Cancers


sentences: Improving genomically recoded Escherichia coli for the production of proteins containing non-canonical amino acids


sentences: Synthetic Condensed-Phase Signaling Expands Kinase Specificity and Responds to Macromolecular Crowding


sentences: Constructing synthetic-protein assemblies from de novo designed 310 helices


sentences: The protein organization of a red blood cell

labels: systems biology


sentences: Develop an efficient and specific AAV-based labeling system for Muller glia in mice


sentences: Transcriptomic heterogeneity of Sox2-expressing pituitary cells


sentences: Cerebrospinal fluid formation is controlled by membrane transporters to modulate intracranial pressure


sentences: Innate lymphoid cells lacking surface expression of CD90 are functional

labels: immunology


sentences: Proteome Microarray Screening Identifies Human Polyphosphate-Binding Proteins in the Phosphatidylinositol Signaling Pathway


sentences: Mitochondrial fission dysfunction alleviates heterokaryon incompatibility-triggered cell death in the industrial filamentous fungus Aspergillus oryzae


sentences: Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA


sentences: Circadian clock function does not require the histone methyltransferase MLL3


sentences: Polyclonal pathogen populations accelerate the evolution of antibiotic resistance in patients

labels: evolutionary biology


sentences: Evolution of plasmid mobility: origin and fate of non-conjugative plasmids


sentences: The 3D architecture of the pepper (Capsicum annum) genome and its relationship to function and evolution

labels: genomics


sentences: Chromosome-level genome assembly of the functionally extinct northern white rhinoceros (Ceratotherium simum cottoni).


sentences: Geometrical frustration of phase-separated domains in Coscinodiscus diatom frustules

labels: biophysics


sentences: Single Molecule Analysis of differential functional mechanisms of MtRecG while being exposed to variants of stalled replication-fork


sentences: Genetic Subtypes of Smoldering Multiple Myeloma are associated with Distinct Pathogenic Phenotypes and Clinical Outcomes


sentences: 3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib


sentences: A mechanistic investigation of enhanced nitrogen use efficiency in wheat seedlings after treatment with a precision engineered Ascophyllum nodosum biostimulant

labels: plant biology


sentences: Leptin-mediated suppression of food intake by conserved Glp1r-expressing neurons prevents obesity


sentences: A new animal model signifying a decisive bridge between innate immunity and the pathognomonic morphological characteristics of Type 1 Diabetes


sentences: Myosin phosphatase target subunit 1 governs integrity of the embryonic gut epithelium to circumvent atresia development in medaka, Oryzias latipes


sentences: The population genetics of adaptation through copy-number variation in a fungal plant pathogen


sentences: Human pathogenic RNA viruses establish non-competing lineages by occupying independent niches


sentences: Extend Mixed Models to Multi-layer Neural Networks for Genomic Prediction Including Intermediate Omics Data

labels: genetics


sentences: Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology


sentences: Phylogenomic analyses of Snodgrassella isolates from honeybees and bumblebees reveals taxonomic and functional diversity


sentences: Single-fiber nucleosome density shapes the regulatory output of a mammalian chromatin remodeling enzyme


sentences: Manipulating Histone Acetylation Leads to Adverse Effects in Hemangiosarcoma Cells

labels: cancer biology


sentences: Sequence diversity in the 3' untranslated region of alphavirus modulates IFIT2-dependent restriction in a cell type-dependent manner


sentences: Chloride-dependent mechanisms of multimodal sensory discrimination and neuropathic sensitization in Drosophila


sentences: Entorhinal cortex directs learning-related changes in CA1 representations


sentences: Ion channel distributions in cortical neurons are optimized for energy-efficient active dendritic computations


sentences: Disruption in structural-functional network repertoire and time resolved subcortical-frontoparietal connectivity in disorders of consciousness


sentences: Insights into bear evolution from a Pleistocene polar bear genome


sentences: Multiple genes in cis mediate the effects of a single chromatin accessibility variant on aberrant synaptic development and function in human neurons


sentences: The human thalamus orchestrates neocortical oscillations during NREM sleep.


sentences: The T cell receptor repertoire reflects the dynamics of the immune response to vaccination


sentences: Identification of novel Ebola virus inhibitors using biologically contained virus


sentences: Microtubule-associated IQD9 guides cellulose synthase velocity to shape seed mucilage

labels: biochemistry


sentences: NFE2L1-mediated proteasome function protects from ferroptosis


sentences: ClusTRace, a bioinformatic pipeline for analyzing clusters in virus phylogenies

labels: bioinformatics


sentences: A two-component protein condensate of EGFR and Grb2 regulates Ras activation at the membrane


sentences: Metabolic potentials of Liquorilactobacillus nagelii AGA58 isolated from Shalgam based on genomic and functional analysis


sentences: In silico and functional characterisation of an ultra-rare CFTR mutation identifies novel lasso motif interactions regulating channel gating

labels: molecular biology


sentences: Ubiquitin proteomics reveals critical targets of the Nse1 RING domain in rDNA and genome stability


sentences: Regulation of mitochondrial proteostasis by the proton gradient


sentences: Glycine targets NINJ1-mediated plasma membrane rupture to provide cytoprotection

labels: cell biology


sentences: Plant morphometry matches beetle diversity: effects of natural adjacent vegetation on grain Amaranth crop under small-holder conditions

labels: ecology


sentences: Extreme drought triggers transition to an alternative soil microbial state


sentences: Tabula Microcebus: A transcriptomic cell atlas of mouse lemur, an emerging primate model organism


sentences: A Dual-reporter Platform for Screening Tumor-targeted Extracellular Vesicles

labels: bioengineering


sentences: Prolonged XPO1 inhibition is essential for optimal anti-leukemic activity in NPM1-mutated AML


sentences: De-novo generation of novel phenotypically active molecules for Chagas disease from biological signatures using AI-driven generative chemistry

labels: pharmacology and toxicology


sentences: Translation rescue by targeting Ppp1r15a upstream open reading frame in vivo

labels: physiology


sentences: Food Restriction Augmented Alpha1 Adrenergic Mediated Contraction in Mesenteric Arteries


sentences: Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion


sentences: IGF1 Receptor Regulates Upward Firing Rate Homeostasis via the Mitochondrial Calcium Uniporter

labels: neuroscience


sentences: Coral larvae suppress the heat stress response during the onset of symbiosis thereby decreasing their odds of survival


sentences: Phylogenomics unravels the early diversification of fungi


sentences: Sensitizing solid tumors to CAR-mediated cytotoxicity using synthetic antigens


sentences: Characterization of individual HIV-1 budding event using ultra-fast atomic force microscopy reveals a multiplexed role for VPS4


sentences: Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size.


sentences: Clonal hematopoiesis is driven by aberrant activation of TCL1A


sentences: 21/2-minute 3D 7T 31P-MRSI of the human heart using concentric rings (CRT)


sentences: Reliability of transcranial magnetic stimulation evoked potentials to detect the effects of theta-burst stimulation of the prefrontal cortex


sentences: Test-retest reproducibility of in vivo magnetization transfer ratio and saturation index in mice at 9.4 Tesla


sentences: Predicting proprioceptive cortical anatomy and neural coding with topographic autoencoders


sentences: ForestScanner: A mobile application for measuring and mapping trees with LiDAR-equipped iPhone and iPad


sentences: The economic burden of protecting islands from invasive alien species


sentences: Developing an empirical model for spillover and emergence: Orsay virus host range in Caenorhabditis


sentences: Measuring drift by mean deviation: unequal breeding sex ratio revisited


sentences: Climate Change, Crop Wild Relatives and Genomic Data: The persistence and agronomic utility of five Vitis species


sentences: A Transcriptomic and Proteomic Atlas of Obesity and Type 2 Diabetes in Cynomolgus Monkeys


sentences: Computer Modeling of Radiofrequency Cardiac Ablation including Heartbeat-Induced Electrode Displacement


sentences: A single latent channel is sufficient for biomedical image segmentation


sentences: Discrete Protein Metric (DPM): A new image similarity metric to calculate accuracy of deep learning-generated cell focal adhesion predictions


sentences: OptDesign: Identifying Optimum Design Strategies in Strain Engineering for Biochemical Production


sentences: robustica: customizable robust independent component analysis

labels: systems biology


sentences: Sensory convergence in the world s largest cavefish diversification: patterns of neuromast evolution, distribution and associated behaviour in Sinocyclocheilus

labels: zoology


sentences: High-speed, multi-Z confocal microscopy for voltage imaging in densely labeled neuronal populations


sentences: Evaluating denoising strategies in resting-state fMRI in traumatic brain injury (EpiBioS4Rx)


sentences: Theta and gamma hippocampal-neocortical oscillations during the episodic-like memory test: impairment in epileptogenic rats


sentences: Passive inertial damping improves high-speed gaze stabilization in hoverflies


sentences: Neural mechanisms to exploit positional geometry for collision avoidance


sentences: A somatosensory computation that unifies bodies and tools


sentences: Presence and the global implications of plastics in wild commercial fish in the Alboran Sea


sentences: Human and wildlife use of mountain glacier habitat in western North America


sentences: Idea paper: An envelope model of ecological disturbance


sentences: Brain regulatory program predates central nervous system evolution

labels: evolutionary biology


sentences: TIMSCONVERT: A workflow to convert trapped ion mobility data to open data formats


sentences: Video-Based Deep Learning to Detect Dyssynergic Defecation with 3D High-Definition Anorectal Manometry


sentences: Comparative analysis of gene prediction tools for viral genome annotation


sentences: Buffering of transcription rate by mRNA half-life is a conserved feature of Rett syndrome models


sentences: Two Stages of Speech Envelope Tracking in Human Auditory Cortex Modulated by Speech Intelligibility


sentences: Peptide Aggregation Induced Immunogenic Rupture (PAIIR)


sentences: A qualitative mathematical model of immunocompetence with applications to SARS-CoV-2 immunity


sentences: Cell Surface SARS-CoV-2 Nucleocapsid Protein Modulates Innate and Adaptive Immunity

labels: microbiology


sentences: Present and future distribution of bat hosts of sarbecoviruses: implications for conservation and public health


sentences: Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces

labels: biophysics


sentences: Structure of the 5' untranslated region in SARS-CoV-2 genome and its specific recognition by innate immune system via the human oligoadenylate synthase 1


sentences: Transcriptional and Cytotoxic Responses of Human Intestinal Organoids to Interferon Types I, II, and III

labels: immunology


sentences: Acetyltransferases GCN5 and PCAF are required for B cell maturation


sentences: Cell transcriptomic atlas of the non-human primate Macaca fascicularis


sentences: Conformational variation in enzyme catalysis: A structural study on catalytic residues


sentences: High performance of a GPU-accelerated variant calling tool in genome data analysis


sentences: Contrastive Cycle Adversarial Autoencoders for Single-cell Multi-omics Alignment and Integration


sentences: Stabilization of Microbial Communities by Responsive Phenotypic Switching


sentences: Landscape of epithelial-mesenchymal plasticity as an emergent property of coordinated teams in regulatory networks


sentences: Continual reelin signaling by the prime neurogenic niche of the adult brain


sentences: FLAMs: A self-replicating ex vivo model of alveolar macrophages for functional genetic studies


sentences: The Omicron variant is highly resistant against antibody-mediated neutralization - implications for control of the COVID-19 pandemic


sentences: Quantification of nuclear transport inhibition by SARS-CoV-2 ORF6 using a broadly applicable live-cell dose-response pipeline


sentences: PTRN-1/CAMSAP and NOCA-2/NINEIN are required for microtubule polarity in Caenorhabditis elegans dendrites


sentences: Antimicrobial resistance determinants in silage

labels: genomics


sentences: Mutations in RBD of SARS-CoV-2 Omicron variant result stronger binding to human ACE2 protein


sentences: SARS-CoV2 variant-specific replicating RNA vaccines protect from disease and pathology and reduce viral shedding following challenge with heterologous SARS-CoV2 variants of concern


sentences: SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling


sentences: Improved neutralization of the SARS-CoV-2 Omicron variant after Pfizer-BioNTech BNT162b2 COVID-19 vaccine boosting


sentences: Following the track: accuracy and reproducibility of predation assessment on artificial caterpillars


sentences: Epistatic models predict mutable sites in SARS-CoV-2 proteins and epitopes


sentences: No evidence of paralogous loci or new bona fide microRNAs in telomere to telomere (T2T) genomic data


sentences: Personalized models of breast cancer desmoplasia reveal biomechanical determinants of drug penetration


sentences: EraSOR: Erase Sample Overlap in polygenic score analyses


sentences: Black chromatin is indispensable for accurate simulations of Drosophila melanogaster chromatin structure.


sentences: Acoustic camera system for measuring ultrasound communication in mice


sentences: Localized, time-dependent responses of rat cranial bone to repeated mild traumatic brain injuries


sentences: Adaptive discrimination of antigen risk by predictive coding in immune system


sentences: Dehalobium species implicated in 2,3,7,8-tetrachloro-p-dioxin dechlorination in the contaminated sediments of Sydney Harbour Estuary


sentences: Acyl-CoA Thioesterases; a rheostat that controls activated fatty acids modulates dengue virus serotype 2 replication


sentences: Microbial associations with Microscopic Colitis


sentences: Stressed out underground?: Transcriptomics illuminates the genome-wide response to heat stress in surface and subterranean diving beetles


sentences: genomicSimulation: fast R functions for stochastic simulation of breeding programs

labels: genetics


sentences: Protective effect of peroxisome proliferator-activated receptor- in regulating the early inflammation response to extended hepatectomy from a comparative transcriptomic analysis


sentences: Multiscale mechanical models of DNA nanotubes: A theoretical basis for the design and tuning of DNA nanocarriers


sentences: The Prion Protein Octarepeat Domain Forms Transient β-sheet Structures Upon Residue-Specific Cu(II) and Zn(II) Binding


sentences: Dynamics of CTCF and cohesin mediated chromatin looping revealed by live-cell imaging


sentences: Biocatalytic Formation of Novel Polyesters with para-Hydroxyphenyl groups in the Backbone - Engineering Cupriavidus necator for production of high-performance materials from CO2 and electricity

labels: synthetic biology


sentences: In vitro validation of neoantigen prediction algorithm for developing personalized cancer vaccine therapy


sentences: Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.


sentences: Disruption of c-di-GMP signaling networks unlocks cryptic expression of secondary metabolites during biofilm growth in Burkholderia pseudomallei


sentences: Insights into the role of lipoteichoic acids in Bacillus subtilis- a new function for MprF


sentences: Scalable batch-correction method for integrating large-scale single-cell transcriptomes

labels: bioinformatics


sentences: Single-molecule sizing through nano-cavity confinement


sentences: Yield is negatively correlated with nucleotide-binding leucine-rich repeat gene content in soybean

labels: plant biology


sentences: Bacteria-derived peptidoglycan triggers an NF-kB dependent response in Drosophila gustatory neurons


sentences: Rapid generation of ventral spinal cord-like astrocytes from human iPSCs for modeling non-cell autonomous mechanisms of lower motor neuron disease


sentences: Molecular Epidemiology and Microbiological Characteristics of Cryptococcus gattii VGII isolates from China


sentences: Integrative interactome and ubiquitinome analyses reveal multiple regulatory pathways targeted by ICP0 in HSV-1 infected neuronal cells


sentences: An amphipathic and cationic antimicrobial peptide kills colistin resistant Gram-negative pathogens in vivo


sentences: The mating type transcription factor MAT1-1-1 from the fungal human pathogen Aspergillus fumigatus: synthesis, purification, and crystallization of the DNA binding domain.


sentences: Seasonal resistome diversity and dissemination of WHO priority antibiotic-resistant pathogens in Lebanese estuaries


sentences: Broad antiviral effects of Echinacea purpurea against SARS-CoV-2 variants of concern and potential mechanism of action


sentences: An mRNA silencing mechanism reliant on the cooperation between REGE-1/Regnase-1 and RLE-1/Roquin-1

labels: molecular biology


sentences: Adeno-associated virus type 2 (AAV2) uncoating is a stepwise process and is linked to structural reorganization of the nucleolus


sentences: Adenine Base Editing in vivo with a Single Adeno-Associated Virus Vector


sentences: Pre-treatment of Nile tilapia (Oreochromis niloticus) with ozone nanobubbles improve efficacy of heat-killed Streptococcus agalactiae immersion vaccine


sentences: A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A


sentences: Oxoglutarate dehydrogenase coordinates myofibril growth by maintaining amino acid homeostasis

labels: cell biology


sentences: Transcription Factor RFX3 Stabilizes Mammary Basal Cell Identity


sentences: A mutation associated with Charcot-Marie-Tooth disease enhances the formation of stable dynamin 2 complexes in cells


sentences: Entangled architecture of rough endoplasmic reticulum (RER) and vacuoles enables topological damping in cytoplasm of an ultra-fast giant cell


sentences: Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii


sentences: Absolute Scaling of Single-Cell Transcriptomes Reveals Pervasive Hypertranscription in Adult Stem and Progenitor Cells


sentences: The anti-angiogenic compound dimethyl fumarate inhibits the serine synthesis pathway and increases glycolysis in endothelial cells

labels: biochemistry


sentences: Modelling biochemical gradients in vitro to control cell compartmentalization in a microengineered 3D model of the intestinal epithelium

labels: bioengineering


sentences: Modeling of microRNA-derived disease network repurposes methotrexate for the prevention and therapy of abdominal aortic aneurysm in mice


sentences: A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1

labels: cancer biology


sentences: Metabolitin-based molecular drug delivery by targeting GPR158 in glioblastoma


sentences: Mitochondrial Dysfunction is a Driver for SP-2509 Drug Resistance in Ewing Sarcoma


sentences: Endoplasmic reticulum oxidoreductin (ERO) provides resilience against reductive stress and hypoxic conditions by mediating luminal redox dynamics


sentences: Spatial Meta-transcriptomes of human and murine intestines


sentences: Progressive alterations of striatal polysomal architecture in a mouse model of Huntington's disease

labels: neuroscience


sentences: Effects of active and passive enrichment regimes on fecal glucocorticoid metabolite levels in captive Indian leopards (Panthera pardus fusca)

labels: ecology


sentences: Pose-gait analysis for cetaceans with biologging tags

labels: animal behavior and cognition


sentences: Pentoxifylline-induced Protein Expression Change in RAW 264.7 Cells as Determined by Immunoprecipitation-based High Performance Liquid Chromatography

labels: pharmacology and toxicology


sentences: Genetic evidence that uptake of the fluorescent analog 2NBDG occurs independently of known glucose transporters


sentences: Single cell genome sequencing of laboratory mouse microbiota improves taxonomic and functional resolution of this model microbial community

labels: microbiology


sentences: Salubrinal induces fetal hemoglobin expression via the stress-signaling pathway in human sickle erythroid progenitors and sickle cell disease mice


sentences: Comparison of biological features of wild European rabbit mesenchymal stem cells derived from different tissues.


sentences: Characterization of metabolic compartmentalization in the liver using spatially resolved metabolomics


sentences: Metabolic properties of murine kidney mitochondria


sentences: Gross anatomy of the gluteal and posterior thigh muscles in koalas based on their innervations

labels: zoology


sentences: Inactivation of SARS-CoV-2 and influenza A virus by spraying hypochlorous acid solution and hydrogen peroxide solution in the form of Dry Fog


sentences: Temporally precise movement-based predictions in the mouse auditory cortex


sentences: Characterizing the Behavioral and Neuroendocrine Features of Susceptibility and Resilience to Social Stress


sentences: Arousal elevation drives the development of oscillatory vocal output


sentences: Models for Evaluation of Biological Age Based on Multi-omics


sentences: KRAS G12D can be targeted by potent salt-bridge forming inhibitors


sentences: Combined Pan-, Population-, and Phylo-Genomic Analysis of Aspergillus fumigatus Reveals Population Structure and Lineage-Specific Diversity


sentences: Fatquant: An automated image analysis tool for identification of fat cells in heterogeneous hematoxylin and eosin tissue sections.


sentences: Unexpected short- and long-term effects of chronic adolescent HU-210 exposure on emotional behavior


sentences: Brassica napus genes Rlm4 and Rlm7, conferring resistance to Leptosphaeria maculans, are alleles of the Rlm9 wall-associated kinase-like resistance locus


sentences: Brain injury environment critically influences the connectivity of transplanted neurons


sentences: Modeling Synaptic Effects of Anesthesia and its Cortical Cholinergic Reversal


sentences: Virtual reality-based sensorimotor adaptation shapes subsequent spontaneous and naturalistic stimulus-driven brain activity


sentences: biPACT: a method for three-dimensional visualization of mouse spinal cord circuits of long segments with high resolution


sentences: Impaired dynamics of prefrontal beta-band networks during cognitive action control in Parkinson's disease


sentences: Neuroimaging signature associated with symptom exacerbation in early-stage psychosis


sentences: Synthesis and Evaluation of Acridone and Xanthone Epoxides with Anti-MRSA and Anti-MSSA Activity


sentences: Regenerated crustacean limbs are precise replicas

labels: developmental biology


sentences: There and Back to the Present: An Evolutionary Tale on Biological Diversity


sentences: Coevolution of the olfactory organ and its receptor repertoire in ray-finned fishes

labels: evolutionary biology


sentences: Combining biomarker and virus phylogenetic models improves epidemiological source identification


sentences: Spontaneous parthenogenesis in the parasitoid wasp Cotesia typhae: low frequency anomaly or evolving process?


sentences: Both Prey and Predator Features Determine Predation Risk and Survival of Schooling Prey


sentences: REVOLVER: a low-cost automated protein purifier based on parallel preparative gravity column workflows


sentences: Structure and dynamics of human disease-complication network


sentences: Mechanism Driven Early Stage Identification and Avoidance of Antisense Oligonucleotides Causing TRL9 Mediated Inflammatory Responses in Bjab cells


sentences: Unveiling effects of growth conditions on crown architecture and growth potential of Scots pine trees


sentences: N-glycosylation modulates enzymatic activity of Trypanosoma congolense trans-sialidase


sentences: Genome edited colorectal cancer organoid models reveal distinct microRNA activity patterns across different mutation profiles


sentences: Water droplet-in-oil digestion method for single-cell proteomics

labels: systems biology


sentences: Dynamic Boolean modelling reveals the influence of energy supply on bacterial efflux pump expression


sentences: Tissue Optimisation Strategies for High Quality Ex Vivo Diffusion Imaging


sentences: Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma