'''[[Cilija|Cilijski]] i [[flagela|flagelno]] vezani protein 298''' jest [[protein]] koji je kod [[ljudi]] [[kodon|kodiran]] [[gen]]om '''CFAP298''' sa [[hromosom 21|hromosoma 21]].  Zanimljiv je i zbog povezanosti s raznim bolestima. Utvrđen je u visokim razinama u [[koštana srž|koštanoj srži]] pacijenata s negativnom prognozom [[AML|akutne mijeloidne leukemije]] i abnormalnim [[kariotip]]om.<ref name="pmid15084693">{{cite journal | vauthors = Bullinger L, Döhner K, Bair E, Fröhling S, Schlenk RF, Tibshirani R, Döhner H, Pollack JR | display-authors = 6 | title = Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia | journal = The New England Journal of Medicine | volume = 350 | issue = 16 | pages = 1605–16 | date = april 2004 | pmid = 15084693 | doi = 10.1056/NEJMoa031046 | s2cid = 13205096 }}</ref><ref name="pmid16931630">{{cite journal | vauthors = Greiner J, Schmitt M, Li L, Giannopoulos K, Bosch K, Schmitt A, Dohner K, Schlenk RF, Pollack JR, Dohner H, Bullinger L | display-authors = 6 | title = Expression of tumor-associated antigens in acute myeloid leukemia: Implications for specific immunotherapeutic approaches | journal = Blood | volume = 108 | issue = 13 | pages = 4109–17 | date = decembar 2006 | pmid = 16931630 | doi = 10.1182/blood-2006-01-023127 | s2cid = 15937337 | doi-access = free }}</ref><ref name="pmid19903898">{{cite journal | vauthors = Bullinger L, Ehrich M, Döhner K, Schlenk RF, Döhner H, Nelson MR, van den Boom D | title = Quantitative DNA methylation predicts survival in adult acute myeloid leukemia | journal = Blood | volume = 115 | issue = 3 | pages = 636–42 | date = januar 2010 | pmid = 19903898 | doi = 10.1182/blood-2009-03-211003 | s2cid = 13349367 }}</ref> Muški pacijenti s [[Alzheimerova bolest|Alzheimerovom bolešću]] pokazali su smanjenje ekspresije ''CFAP298'' u njihovim [[krvne ćelije|krvnim ćelijama]].<ref name="pmid16979800">{{cite journal | vauthors = Maes OC, Xu S, Yu B, Chertkow HM, Wang E, Schipper HM | title = Transcriptional profiling of Alzheimer blood mononuclear cells by microarray | url = https://archive.org/details/sim_neurobiology-of-aging_2007-12_28_12/page/1795 | journal = Neurobiology of Aging | volume = 28 | issue = 12 | pages = 1795–809 | date = decembar 2007 | pmid = 16979800 | doi = 10.1016/j.neurobiolaging.2006.08.004 | s2cid = 8185187 }}</ref><ref name="pmid19366883">{{cite journal | vauthors = Maes OC, Schipper HM, Chertkow HM, Wang E | title = Methodology for discovery of Alzheimer's disease blood-based biomarkers | journal = The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences | volume = 64 | issue = 6 | pages = 636–45 | date = juni 2009 | pmid = 19366883 | doi = 10.1093/gerona/glp045 | doi-access = free }}</ref> [[Gen]] ''CFAP298'' nalazi se unutar kritične regije za [[Downov sindrom]].<ref name="pmid20502642">{{cite journal | vauthors = Moncaster JA, Pineda R, Moir RD, Lu S, Burton MA, Ghosh JG, Ericsson M, Soscia SJ, Mocofanescu A, Folkerth RD, Robb RM, Kuszak JR, Clark JI, Tanzi RE, Hunter DG, Goldstein LE | display-authors = 6 | title = Alzheimer's disease amyloid-beta links lens and brain pathology in Down syndrome | journal = PLOS ONE | volume = 5 | issue = 5 | pages = e10659 | date = maj 2010 | pmid = 20502642 | pmc = 2873949 | doi = 10.1371/journal.pone.0010659 | doi-access = free | bibcode = 2010PLoSO...510659M }}</ref>  Nema jasnih [[paralog]]a kod ljudi, ali gen ima [[Homologija sekvence|homologe]] široko kozervirane među [[životinja]]ma, [[gljiva]]ma i [[alga]]ma.