NVMe over Fabrics (NVMe-oF) is a network protocol that allows NVMe storage devices to be accessed remotely over a network. It provides direct memory access (DMA) communication between storage devices and servers or clients. It allows for better performance, reduced latency, and higher throughput than traditional network protocols like Fibre Channel (FC).
On the other hand, FC NVMe uses Fibre Channel as the transport layer and has some limitations in terms of scalability, flash storage, capacity, and performance compared to NVMe-oF. NVMe-oF is a more efficient and scalable solution for accessing NVMe storage devices over a network.