An organoid is a miniaturized and simplified version of an organ fabricated in vitro in three dimensions that mimics the essential functional, structural, and biological complexity of that organ. These tissue biorepositories provide a record of genetic heterogeneity between patients and present patient-derived samples that can be propagated for research purposes, making them invaluable tools for basic research. Organoid systems are currently used to model cancer development and treatment. Cancer research has been limited due to the lack of in vitro models that can accurately replicate the physiology of the original tumor. There are potentially as many types of organoids as different tissues and organs in the body. Researchers have created organoids that resemble the brain, kidney, lung, intestine, stomach, and liver. However, organoids lack a vasculature and are cultured using static methods. As the organoids grow, the cells in the center need more nutrients, and waste exchange becomes difficult...Read more