The modern Sphynx cat originated in 1966 in Toronto, Canada, from a litter of domestic shorthair cats that included a hairless kitten due to a random genetic mutation. This sparked interest among breeders in North America and Europe, who selectively bred hairless cats to establish the Sphynx breed. The breeding efforts led to a genetically diverse and vigorous Sphynx breed known for its unique hairless appearance. This breed's development highlights the role of genetic variation in shaping distinct feline breeds.