Causes of sexual dysfunctions can be physical, psychological or related to interpersonal relationships or sociocultural influences. Psychological causes can include:stress or anxiety from work or family responsibilitiesconcern about sexual performanceconflicts in the relationship with your partnerdepressionunresolved sexual orientation issuesprevious traumatic sexual experiencebody image and self-esteem problemsPhysical causes can include:diabetesheart diseaseliver diseasekidney diseasepelvic surgerypelvic injury or traumaneurological disordersmedication side effectshormonal changes, including those related to pregnancy and menopausethyroid diseasealcohol or drug abuse