– Pharmacology, mechanism of action, or therapeutic class
2.2 – Commercial availability; prescription or non-prescription status; brand, generic, or biosimilar names; physical descriptions; or how supplied
2.3 – Boxed warnings or REMS
2.4 – Pregnancy or lactation
Approximately 14% of the exam is dedicated to Area 2. This area tests the understanding of medications, including mechanism of action, brand and generic drug names, availability (eg, prescription vs. OTC), and pertinent safety issues (eg, boxed warnings, use in pregnancy).