Yes, you can and you should. Recovering from knee injuries typically involves sleeping with knee wraps or orthopedic knee braces to stabilize the joints, promote healing, and alleviate pain. You might feel uncomfortable at first, but if the knee support is fitted correctly, you will soon see only the benefits. It is best if you sleep on your back and elevate your leg with a pillow below the knee brace. If you need to sleep on your side, consider supporting your back with additional pillows. Give wedge pillows a try.