After taking the covid-19 vaccine, most people experience some form of discomfort in their arm, pain, and flu-like symptoms. It is safe to take an Ibuprofen tablet after your covid-19 vaccine to ease the symptoms. Doing so does not reduce the effect of the vaccine or your body's immune response. You can take one tablet or capsule and follow it up with a second one (if required) after 6-8 hours of the first tablet.