A throat lump may go away with treatment. If a healthcare professional discovers a growth or lesion in the throat, they may treat it with endoscopy or surgery. Globus is different — it is a feeling of a lump in the throat when a lump is not present. Globus may resolve with reassurance — from a medical professional — that there is nothing physically wrong with your throat or after treatment of related causes, such as GERD or postnasal drip.