Cefpodoxime is commonly used to treat different kinds of skin infections in dogs and puppies older than 18 days. It can also be used to treat respiratory and urinary tract infections. The United States Food and Drug Administration (FDA) has approved the use of products containing Cefpodoxime in dogs. The following dog conditions are commonly treated with cefpodoxime include: Ear infection, Skin infection... Check out all you need to know about cefpodoxime for dogs.