As gynecomastia progresses, you may observe changes in the appearance and sensitivity of your nipples. Many men notice their nipples becoming more pronounced or larger. The areolas surrounding the nipples also tend to get bigger, puffy, and swollen. Along with the physical changes, they are likely to become more sensitive or tender to touch. You may find that even the slightest stimulation or pressure causes significant discomfort or pain around the nipples. Clothing rubbing against them may lead to irritation. Keep in mind that it is normal for male nipples to respond to stimuli, but increased sensitivity paired with other gynecomastia symptoms warrants medical evaluation.