The liver is the body’s largest internal organ, sitting in the upper right portion of the abdomen beneath the diaphragm and above the stomach. Primary liver cancer, meaning cancer that began in the liver, accounts for 42,000 new cases in the United States annually.
Several types of cancer can form in the liver, however not all cancers that affect the liver are considered liver cancer. Cancer that begins in another area of the body, such as in the colon or breast, and then spreads to the liver is called metastatic cancer rather than liver cancer. This type of cancer is named after the organ in which it began; for example, metastatic colon cancer describes cancer that begins in the colon and spreads to the liver. Cancer that spreads to the liver is more common than cancer that initially begins in the liver cells.
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