In skin cancer, the mnemonic changes ABCDE stands for – A – Asymmetry – in skin cancer (melanoma) unsymmetrical moles appear on the skin and soon turn into wounds that bleed. Non–cancerous moles are symmetrical in nature B – Border – The cancerous moles are bulgy with an indefinite border, while the non-cancerous one is flat and smooth with a definite border. C – Color – They are usually different in color and are mostly red. D - Diameter - Usually the diameter is 6 mm in diameter E – Evolving – They often change shape and size. Usually, develop in sores or bleeding wounds.