Bladder analgesics such as phenazopyridine (Pyridium, AZO, etc.) would provide most patients relief from the dysuria and urinary frequency. It is not an antibiotic, however, so it will not treat a bacterial infection. D-Mannose is a supplement that has been shown to prevent UTIs and is also widely available. Patients with E. coli infections can take D-Mannose and AZO to avoid antibiotic treatment for UTIs.