Though there are some medications that should never be used together, in other cases two medications that interact can be used together even though they interact. In these cases your doctor will likely change the dose or take other precautions.
The following medications may interact with paromomycin:
Amifampridine
Colistimethate Sodium
Foscarnet
Digoxin
This is not an exhaustive list of drug interactions that may occur. Make sure that you let your doctor know about all medications you are taking before starting paromomycin. Give them a list with the prescription and non-prescription drugs, herbal products, and vitamins you take. This will help you to avoid negative side effects from interactions. If you have questions about drug interactions, you can call 1-844-416-4282 and ask to be transferred to a licensed pharmacist.