Even though two days in Florence are preferable to none, it could be challenging to experience everything it has to offer in that little time. But it is possible to visit many of the top sights as well as experience some of the distinctive cuisine and culture of the city with proper preparation and prioritization. A two-day visit to Florence should include seeing the Duomo, the Uffizi Gallery, the Ponte Vecchio, and the Piazza della Signoria, among other sights. It's also worthwhile to take a trip through the Oltrarno neighborhood to observe the city's vibrant arts and crafts scene and enjoy some of the fantastic regional cuisines.