Some of the possible causes of peripheral neuropathy are preventable. You can also lower your chances of developing it by preventing or delaying certain conditions. In general, the best preventive or precautionary steps you can take include:   Eating a balanced diet. Certain vitamin deficiencies, especially vitamin B12 deficiency, can affect your nervous system and cause major problems. Other vitamins, especially B6, are toxic and cause peripheral neuropathy at high levels. Staying physically active and maintaining a healthy weight. This, along with managing your diet, can help prevent or delay the onset of type 2 diabetes, which damages your peripheral nerves over time. Wearing safety equipment as needed. Injuries are a major source of nerve damage. Using safety equipment during work and play activities can protect you from these injuries or limit how severe the injuries are. Managing chronic conditions as recommended. If you have a chronic condition that can affect your peripheral nerves, especially type 2 diabetes, it’s important to manage it as your healthcare provider recommends. That can limit the effects of the condition or delay how long it takes to get worse. Avoiding alcohol in excess. Excessive consumption of alcohol is a proven cause of peripheral neuropathy. You can reduce your risk of neuropathy (and some other medical complications) by avoiding alcohol, or consuming it in moderation only. Avoiding exposures to toxins, poisons and heavy metals. Heavy metals like lead and mercury can cause severe damage to your nervous system. Mercury exposure is rare thanks to environmental regulations, but older thermometers or thermostats may still contain it. Older homes may also contain lead-based paint. Local, state and national agencies may have resources and services to help you avoid exposure to toxic metals and chemicals. If you work around such metals and chemicals, follow all safety regulations and use recommended or required protective gear.