Regarding the expenditure of treating stage 4 or metastatic cancer can run into many dollars or rupees depending on the type of cancer. Furthermore the cost also depends on the exact treatment procedure to be followed and also the country in which treatment is being done.Access to insurance also has a significant role to play when it comes to out-pocket cost management. Cancer in Stage 4 is a painful journey for the patient and his/her family – physical, emotional, and financial expenses of cancer treatment is enormous. One might also go for clinical trials and patient assistance programs which could lead to more costs.