The Ambry Score is known as a polygenic risk score (PRS), which means it can evaluate the genetic variants you inherited at birth, coupled with your age and ethnicity, to determine your individual risk of having developed or eventually developing prostate cancer. The Ambry Score is used in combination with other tests, such as ProstateNext. The Ambry Score analyzes 72 single nucleotide polymorphisms (SNPs). A SNP is an error that exists in your DNA, or genetic code. SNPs are typically inherited from your parents and are unique to each person. Research has shown these 72 SNPs are associated with prostate cancer risk. Test results for Ambry Score are presented in the following fashion: Unaffected males (no current prostate cancer diagnosis): Average remaining lifetime risk of developing prostate cancer (0-10.2%) Above average remaining lifetime risk of developing prostate cancer (>10.2%) Affected males (current prostate cancer diagnosis): Average PRS Score (≤ 1) Above average PRS Score (>1) A PRS Score of above 1 suggests that your cancer may have occurred as a result of an error related to the 72 SNPs, as well as other factors, associated with prostate cancer development. A PRS Score of less than or equal to 1 suggests that your cancer likely did not occur as a result of an error related to the 72 SNPs associated with prostate cancer development. Results from the Ambry Score, along with other personal risk factors and PCMs, can be used by you and your healthcare provider to develop a customized monitoring or treatment plan specific to your risk profile. See a sample Ambry Score report and learn more about how to interpret them.