People having first-degree relatives diagnosed with coeliac disease and genetically predisposed individuals are at greater risk of developing the illness. Individuals with first-degree relatives diagnosed with coeliac disease are more likely to develop the illness. On the other hand, genetically predisposed individuals possessing a single or a pair of celiac genes, i.e. HLA-DQ2 and HLA-DQ8, contract with illness. Moreover, environmental factors play a major role in triggering the condition.