Generally, it is not necessary to remove the seeds from zucchini when making zucchini bread. Zucchini seeds are edible and won't negatively impact the texture or flavor of the bread. However, if the zucchini you are using has large and mature seeds that you find undesirable, you can scoop out some of the seeds before shredding the zucchini. This can help ensure a smoother texture in the final bread.  In most cases, especially when using young and tender zucchini, there's no need to go through the effort of removing the seeds. Just grate the zucchini as a whole and incorporate it into your zucchini bread recipe.