The benefit of Advantage is it kills larvae and fleas very fast and provides instant relief to both your cats and dogs. Pyriproxyfen and Imidacloprid are the active ingredients of Advantage. In contrast with the flea protection tablets, it only takes half an hour for Cheristin to come into action and kill the fleas. The formula is designed especially for cats only, and to get rid of fleas 100 percent, Cheristin takes about half a day. Both Cheristin and Advantage have their benefits. Cheristin can be helpful for the kitten that weighs as low as 1.8 pounds to 2 months old. Advantage is best on cats that are more than eight weeks old.