When a car sits for 2 years, various issues can occur. The battery may be dead, tires could lose air or develop flat spots, and the gas can deteriorate and cause damage to the fuel system. Oil can settle, and seals and gaskets may dry out and crack, causing leaks. The brake system can also seize up due to rust and corrosion. It's recommended to thoroughly inspect and prepare a car before attempting to drive it after such a long period of inactivity.