There are all sorts of active ingredients that are used in these products. Some creams will have a mix of the following while others will stick to just one or two active ingredients to get results. Vasodilators These are ingredients that widen blood vessels allowing more blood to flow into the shaft of the penis. Some examples of this are l-arginine which widens microcapillaries, and ginseng which improves circulation and blood flow. This results in a fuller erection as more blood can flow through the widened blood vessels. Warming or tingling Peppermint, menthol, sweet almond oil, and aloe create a warming or tingling effect which increases blood flow and heightens sensitivity. These ingredients get extra blood flowing into the area resulting in a fuller and firmer erection as well as making you feel more aroused. Caffeine Caffeine may also be used in an enhancing cream to aid the transdermal absorption of the cream to ensure that you get the maximum results from the active ingredients. Butea Superba Butea Superba is a natural inhibitor of PDE-5 which is clinically proven to support the enzymes which control erections. This locks the molecules inside to help maintain a fuller and longer-lasting erection. In plain English, this will temporarily give you a thicker and harder erection. Always make sure you read the ingredients list closely. There are some ingredients that may irritate your skin. These products tend to use ingredients like natural herbs, vitamins, minerals, or hormones. Do a patch test on your skin 24 hours before you want to use the cream. If you are fine and have no side effects, then it should be safe to use all over.