Botox is actually categorized as a neuromodulator, not a filler. This means Botox (along with Xeomin and Dysport) blocks the nerve signals and stops muscle contractions. Dermal fillers, as their name implies, “fill” the wrinkle from beneath. It’s a totally different approach. Dermal fillers are injected beneath a wrinkle and basically fill in the space, pushing the depressed skin (the wrinkle) back upward. Dermal fillers only work on the other type of wrinkle, the static wrinkle. Static wrinkles develop from sun damage, decreasing collagen production, personal habits, and the like. Static wrinkles show themselves at all times, not just when you perform a behavior such as squinting (dynamic wrinkles).