Although you can wash and re-use between uses, fabric protectors and gel protectors can also be wiped using alcohol-based wipes.
Toe protector lining thins over time and therefore should be replaced with new ones. The rate at which your toe protectors wear out depends on the frequency of use. With optimum use, they can last for about a year.
For as long as you will be wearing the toe protector(s), make sure to observe your feet often for any changes.