One Sol Burn is a natural fat burner, and it does not contain any artificial ingredients, stimulants, or fillers. However, this does not mean that it is compatible with all supplements or medications. Some of the ingredients in One Sol Burn may interact with certain drugs or supplements, such as blood thinners, antidepressants, or diabetes medications. Therefore, you should consult your doctor before taking One Sol Burn if you have any medical conditions or are taking any medications.