Several blood tests can determine if you have mono. If you are currently experiencing the symptoms of mono, fatigue, sore throat, swollen lymph glands, and fever, your doctor may order the mono spot blood test. Sometimes the EBV blood test is also ordered for confirmation. The blood test is done by either a finger prick blood test or a blood draw from a vein.
A positive monospot result means there are heterophile antibodies present in the blood and you have mono.
A negative result means there are no heterophile antibodies present, and you may not have mono. If your doctor still suspects mono, they may order the EBV test to confirm.
A positive EBV result confirms that you have EBV antibodies in your blood and shows if you currently have an infection or were infected in the past.
If the EBV results are negative, it means your symptoms are being caused by something else.