No. CoolSculpting uses a proprietary process called cryolipolysis that ensures it targets only fat cells. Cryolipolysis was developed by Harvard researchers, and its safety and effectiveness are well documented.1 Our fat cells are more vulnerable to cold than skin and muscle cells, which are completely undamaged by the low temperatures. The CoolSculpting device also comes equipped with several features to maintain a consistent temperature throughout each treatment, further maximizing its safety.