Murg Makhani and Tikka Masala differ in their origin and the variety of subtle flavors. Murg Makhani, originating from North India, includes a smoother and creamier sauce with a hint of sweetness, whereas Tikka Masala, originating in Britain, features a slightly spicier and chunkier tomato-based sauce. However, their differences contribute to their taste and influence the culinary experience.