Bioavailability of CBD oil is completely dependent on the chosen consumption method. Below is a breakdown:
Intranasal (smoking/vaping) - Currently, inhaling CBD is the most effective way to maximize the dosage because 34-56 percent of the dose directly enters the bloodstream. The effects of this method are typically felt within about 10 minutes.
Sublingual - This entails placing drops of CBD oil under the tongue for a few seconds in order for the sublingual gland to absorb the CBD. Bioavailability ranges typically from 13-19 percent, but may reach over 30 percent. Effects are typically felt within about 20 minutes.
Oral - This method is very popular, but not as effective as intranasal or sublingual with bioavailability ranging from 6 percent to 20 percent. The effects are typically felt within a few hours. CBD oral bioavailability increases to as much as 60 percent with water soluble products.
Topical - Although the bioavailability of topical CBD has not been measured yet, it appears to be lower than other methods, but several studies have demonstrated efficacy for topical CBD when applied directly to targeted areas on the skin for pain relief associated with sore muscles or arthritic joints. Effects with correct dosage can be felt within seconds.