The arrangement of wires in the RJ45 connector is specified by the T568A and T568B wiring standards. Although both standards utilize the same 8-pin connector, the termination of wires within the connector differs for each standard. T568A is commonly used in Europe and some other regions for Ethernet networking, while T568B is preferred in North America. It is essential to maintain consistency in wiring standards throughout the network to ensure proper connectivity and compatibility.