Targeted therapy drugs, such as HER2-targeted therapies (e.g., trastuzumab), are used specifically for breast cancers that overexpress certain proteins or have specific genetic mutations. These drugs target and block the specific molecules responsible for cancer growth. Hormonal therapy, on the other hand, is used for hormone receptor-positive breast cancers. It aims to block the effects of hormones, such as estrogen or progesterone, on cancer cells.