Chest tightness can be a side effect of taking Adderall, which is a stimulant drug used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. Other potential side effects of Adderall include increased heart rate, elevated blood pressure, and increased stress on the heart. If you are experiencing chest tightness or any other concerning symptoms while taking Adderall, it is important to seek medical attention immediately. Additionally, it is important to discuss all potential side effects with a doctor before starting Adderall or any other medication.