Sinemet works by increasing the amount of dopamine in the brain, thus reducing Parkinson's disease symptoms. The recommended way to take the tablet (extended release) is by mouth. Your doctor will determine your dose based on a number of factors. Doctors usually start patients on a low dose and gradually increase it over time.
When starting Sinemet, your doctor may recommend taking one tablet of 10 mg carbidopa / 100 mg levodopa three to four times a day. However, the amount of carbidopa in this dose may not be sufficient to reduce your symptoms. You may be advised to take an extra 1/2 tablet every day or every other day. Your response to treatment may change your recommended dose.
It is important that you carefully read the Patient Information Leaflet. It is available from your pharmacist before you begin taking Sinemet.