Triclazone is a combination of two anti-diabetic medications (Gliclazide and Metformin). Both are very efficacious medications and usually very well tolerated.Metformin in some people can cause bloating, diarrhoea. It should not be given in case of kidney failure. Gliclazide stimulates insulin release from pancreas. It may cause low blood sugars if you miss meals after taking it.