There will be several opportunities for moneyline and point spread upsets in Week 2. We mentioned earlier that you should be on the lookout for unranked teams playing teams ranked No. 20 through No. 25 in the latest AP poll. These teams have won 28 of the last 35 such games, including 6 of 9 in 2022. Don’t blindly bet on this trend. Be sure to do your research and consult the experts at Sports Hub for the best Week 2 NCAA football picks.