Many people experience decreased sleep after taking SSRIs such as sertraline so it is suggested that one should not take it at night as it aggravates insomnia. Other conditions that promote the use of Sertraline in the morning are urinary problems and sexual dysfunction. Zoloft is known to cause urinary incontinence so to avoid frequent breaks in sleep at night and bedwetting in children many people take Zoloft in the morning. Moreover, Sertraline causes sexual dysfunction, and to mitigate this effect one should take the drug in the morning.