Shifting reels can have a significant impact on your chances of winning in a slot game. When winning combinations occur, the shifting action often removes the winning symbols from the reels and replaces them with new ones, allowing for additional potential wins in a single spin. This can lead to extended winning streaks and larger payouts compared to traditional slot games. However, it's essential to understand that the specific mechanics and rules of shifting reels can vary from one game to another, so it's advisable to review the game's instructions and paytable to maximize your winning potential.