The Bohr effect may be found in hemoglobin, which is the phenomenon of a protein's lower binding affinity for oxygen. The H atoms interact with the globin amino acids, stabilizing the deoxyhemoglobin, which is induced by the elevated pH. Root's effect is the phenomenon of oxyhemoglobin's reduced oxygen-carrying capacity, which means that even at high partial oxygen pressures, there is no saturation. This is caused by a high pH level.