While Grapefruit essential oil benefits many people, it may interact with some prescription medications. Research indicates that grapefruit can block the body’s ability to metabolize certain enzymes, which means some drugs may enter the bloodstream too quickly or remain in your system for longer than advised.
You should avoid Grapefruit oil and consult your physician before using it if you are taking statins to lower cholesterol, certain blood pressure and heart medications, antihistamines, organ-transplant drugs, and anti-anxiety medications like bupirone.