The therapeutic benefits of mescaline have been researched somewhat less than the other drugs in Pollan’s series. His interview subjects suggested that it could help treat depression, anxiety and addiction issues. One recent survey appears to back these claims up.
Respondents variously reported that symptoms of depression, anxiety, PTSD and substance abuse disorders had all improved after mescaline use. In a separate survey, users of mescaline and other psychedelics also reported reduced suicidal thinking.