Safety is paramount when setting up a backyard fire pit. First, choose a suitable location away from flammable materials, overhanging branches, and structures. Utilize a fireproof base, like gravel or pavers, to prevent ground fires. Install a spark screen to prevent embers from escaping, and keep a fire extinguisher or water source nearby. Always supervise the fire, especially when children or pets are present, and extinguish it completely before leaving.