Yes. Nest Thermostat and Nest Protect can tell you when you leave your pet inside the house for too long. Nest will also send a notification to your smartphone that the Nest Protect smoke/CO alarm went off, which means something in your home is burning or giving off poisonous gas. Nest works with many common pet door brands (see Nest's Works with Nest page). Nest also has an optional pet-friendly door sensor that you can buy.