The Epson TM-C3500 requires a 1.75" - 2.25" core with a maximum outer diameter of 4". Since our RL4008IW has a 3" core and 6" outer diameter, it would not be recommended for your printer model. We do offer 2" core inkjet rolls but the out diameters would be 5", which is still too large to load in your printer model. If your printer supports accessories like external arms or feeders, then you may be able to use these rolls. I would recommend reaching out to the manufacturer to confirm. You can also request free samples of the material to test: https://www.onlinelabels.com/samples. https://www.onlinelabels.com/materials/inkjet-roll-labels