Cut-off grades are conventionally optimized independently from the long-term mine production schedule, which means that a schedule may no longer be optimal or feasible if the cut-off grade is modified. These pre-defined cut-off grades also do not take into account inherent uncertainty in grade and material types and the complex material blending that happen across the mineral value chain. This has an adverse effect on the NPV. KPI-COSMO enables the user to simultaneously optimize the cut-off grades and the schedules accounting for the uncertainties in the available mineral resources and multiple operational capacities in the value chain. This leads to significant improvement in NPV compared to the conventional cut-off grades.