The problem is that the user does not have required file access permission to perform a file read, write, edit or delete. To fix this issue, request that your systems administrator grant “Users” full control to the directory “c:\\ProgramData\\Microbio”:
Open file explorer and navigate to the directory “c:\\ProgramData\\Microbio”
Open the property window for “c:\\ProgramData\\Microbio”
From the “Group or user names:“ section, select the profile “Users“. Click “Edit“ button
In the “Permissions for Users“ section, select full control. Click “Apply“ button, then “OK“ button.