Different medical spas will have different methods for alleviating your pain during your Daxxify treatment. If you've been getting Botox for a few years now, you know that most medical spas offer numbing creams, ice packs, and other ways to alleviate pain. If your pain tolerance is average, these topical pain-relief remedies should be more than enough to make your Daxi treatment into a walk-in-the-park... a walk-in-the-park where the fresh air significantly reduces your wrinkles.