To expand the scope of this photobiocatalytic approach for synthesizing a broader range of non-canonical amino acids, several strategies can be employed. Firstly, exploring the use of different organoboron reagents with varying functional groups can lead to the synthesis of diverse non-canonical amino acids. By optimizing the reaction conditions and substrate specificity of the engineered pyridoxal biocatalysts, a wider range of amino acid derivatives can be accessed. Additionally, incorporating different oxidizing agents and fine-tuning the photoredox catalysts can enhance the selectivity and efficiency of the oxidative coupling reactions, enabling the synthesis of novel non-canonical amino acids with unique structural features.