Many people choose to drive to Key West from Miami along U.S. Route 1—don’t worry about directions, you just follow the road until it ends! The total journey takes about three to four hours and requires you to cross 42 bridges (it’s pretty surreal and can feel like you’re driving on water). Buses also run that same route. Alternatively, you can fly directly to Key West International Airport. No matter how you get there, you’ll be glad you made the trip.