Depending on availability and other factors, you may take two different medications (mifepristone and misoprostol) or only one type of medication (just misoprostol) for a medication abortion. If you’re having a medication abortion using two different medications (mifepristone and misoprostol), and your abortion appointment is in person, the provider will give you the first medication (mifepristone) at the health center and the second medication (misoprostol) to use up to 48 hours later at home (or somewhere else safe and comfortable).