According to Centers for Disease Control and Prevention (CDC), In 2020, there were an estimated 38,000 cases of Lyme disease in the United States. However, it is important to note that this number is likely an underestimate, as many cases go unreported. Lyme disease is a bacterial infection caused by the spirochete Borrelia burgdorferi, which is transmitted to humans through the bite of infected black-legged ticks. The disease is named after the town of Old Lyme, Connecticut, where a number of cases were first identified in the 1970s. Symptoms of Lyme disease typically appear within 3 to 30 days of a tick bite.