There are a few different possibilities when it comes to lonely jobs that can make someone feel depressed or isolated. Some of the loneliest jobs in the world include winter caretakers at remote national parks, game wardens watching animals at remote state parks, night watchmen and security personnel for mines, tunnel inspectors, engineers, scientists, or lawyers. In these cases, a “lonely” job can refer to either the physical location of the job, the time of the job’s hours, or professions that work without any other people.