For the most part, EVA foam is considered to be a safe material and a safe alternative to PVC. The reason this is “for the most part” is because it was found that it does contain formamide. And, this has been linked to cancer and is technically considered a developmental toxin. The good news is not all EVA foam will have formamide. And, even if the seller does not specify if their model contains it or not, you can always contact them directly. Generally speaking, this is probably the only potential concern that you will have with this type of material. Because, other than that, EVA foam is not toxic.