Most sour cream containers purchased in the grocery store have an expiration date of about 2 weeks. While we try to use up any leftovers, sometimes you have to decide whether to toss or freeze it. According to Healthline, it is safe to freeze sour cream for up to 2 months. However, the texture will not be smooth and creamy after it has been defrosted. Your best use of defrosted sour cream is to use bit in a creamy soup or stew. Some soup suggestions: Split pea, creamy tomato, pumpkin or sweet potato, butternut squash, cabbage or cream of chicken.