You might. Some people have had withdrawal symptoms after ending their Gleevec treatment. In one small clinical study, 30% of people had muscle or bone pain after stopping Gleevec. The pain was most often in their shoulders, hips, legs, and arms. This withdrawal symptom occurred within one to six weeks of stopping treatment.
About half of the people treated their pain with over-the-counter pain relievers. The other half needed prescription medication. In most people who had these withdrawal symptoms, muscle and bone pain went away within three months to a year or longer.