If you are given a choice of medication, that means they are all safe and appropriate for you to use. We will list the advantages and disadvantages for each option so you can choose which one is right for you. For example, patches can be worn for multiple days and may be more convenient than applying gel daily. They can also be less messy than a gel. On the other hand, gel can be a better option for those with sensitive skin as a patch contains adhesives that may irritate. Read more about the different types of HRT.