Col Du Marine - Collagen is 100% natural and derived from fish. It is free of any other ingredients and additives. This ingredient is a subject of numerous tests, and there no negative or unwanted side-effects have ever been officially registered or noted. It is not recommended to those, who are allergic to fish. Col Du Marine is free of fat and cholesterol of any type. It is hence also suitable for diabetics. However, each substance may bring a negative impact to some extent, if not consumed responsibly. If there is any concern, with regards to dosage and possible side effects we suggest consulting with your therapist before starting the course of the product.