You can use pain relief creams powered by lidocaine safely so long as you follow the directions on the product label. Scientific studies have yet to confirm whether camphor is safe for use during pregnancy, so it's best to be cautious and avoid pain relief creams that feature it. There are no human studies to determine whether menthol is truly safe during pregnancy, but the risk is considered low when the menthol concentration in a pain relief cream is low. If you want to use a methol-powered pain relief cream, consult with your doctor first. While oral arnica consumption is problematic during pregnancy, topical use is generally recognized as safe. However, if you have concerns, consult with your doctor before using these types of pain relief creams. Lastly, you should avoid NSAID-based pain relief creams during your third trimester. Methyl salicylate, a common active ingredient in these products, is absorbed into the body via the skin and can cause harm to the baby and complications during delivery.