Lisa can be run in your main even without constellations. Notably, her second, fourth and last constellations are better upgrades to her playstyle and damage potential. Even if you get to other constellations, you will get a boost in talent levels that eventually contribute to your damage output. One problem about getting Lisa is that you can only obtain her from the standard banner or the paimon starglitter exchange shop that refreshes every rotation. It costs a lot of starglitter to buy a character, and starglitter can be obtained from wishes only.  I was lucky enough to get two constellations of Lisa from the standard banner since I've been playing the game and bought some of them at the starglitter exchange shop. I've been running various team compositions from time to time and recently shifted to mono-element teams because I find them fun to play. Genshin Impact is all about experimentation, and I highly recommend you try new things from time to time.