Nylabone claims that all of its products are manufactured using only non-toxic and pet-safe materials. In the past, questions have been raised about Nylabone products' safety and their causing seizures in dogs. However, the brand came forth with an open statement claiming that the news was false and negative marketing intended to harm the brand's reputation. While Nylabone products are safe, just like with every other toy, caution must be exercised to ensure that your dog doesn't break off pieces of the chew toy and swallow them.