The best way to prep for a colorectal cancer screening will depend on the type of screening scheduled. For a colonoscopy, detailed information on how to prepare will be provided by your gastroenterology team before your scheduled procedure to clean out your colon. Your GI specialist may also give you specific instructions to follow for several days leading up to your exam. It is essential to abide by your physician's directions to help ensure they can identify any areas of concern during your colorectal cancer screening.