Peel and stick the patch on the hairless part of the upper body surface, preferably the inner arm or wrist.  Make sure to clean that area for secure adhesion and it should not have any oil or moisturizer residues.  Wear the patch for 8 to 12 hours, when done, remove the patch and discard it in the trash.  Repeat with the new patch the next day. Do not re-use the same patch.