The FDA says that the information presented and discussed during the workshop series is not intended to inform the Agency’s rulemaking related to deeming additional tobacco products to be subject to the Federal Food, Drug, and Cosmetic Act. But the information-gathering through public comments and research projects may lead to regulations in the future. The e-cigarette industry seems open to FDA involvement to ensure that the products are safely manufactured for all parts of the world, but there is also a fear that strict regulations will favor big tobacco companies, which have the time and money to comply if clinical trials and rigorous manufacturing standards are required. One wonders what will happen in the meantime. The Centers for Disease Control and Prevention (CDC) reports that the number of calls to poison centers involving e-cigarette liquids containing nicotine rose from one per month in September 2010 to 215 per month in February 2014, and more than half of the calls involved young children under age 5. And yes, 16 million minors, age 17 and under, can still buy e-cigarettes in 10 states and the District of Columbia, according to a CDC report. “We know e-cigarettes are not safe for youth,” said Tim McAfee, M.D., M.P.H., director of CDC’s Office on Smoking and Health. “While ENDS (electronic nicotine delivery systems) may have the potential to benefit established adult smokers if used as a complete substitute for all smoked tobacco products, ENDS should not be used by youth and adult non-tobacco users because of the harmful effects of nicotine and other risk exposures, as well as the risk for progression to other forms of tobacco use.” Meanwhile, in Fort Plain, New York, where the toddler died from drinking liquid nicotine, the Albany CBS affiliate reported that “lawmakers like Assemblyman John McDonald are pushing for childproof caps to become a requirement on liquid nicotine vials sold in New York State,” adding that “more needs to be done on a federal level since this product is marketed in a way that can be enticing to children.” “If you look at these little bottles they almost look like candy bottles and therefore to a young person it’s attractive,” McDonald said. “Now I don’t think anyone makes them that way with that intention but the reality is they’re trying to market the scent of the vapor. ” NEJM underscores the need for action in its recent “Perspective” editorial: