We wouldnât advise using 50/50 e-liquid in a sub-ohm tank unless that tank can be equipped with a higher resistance coil. Sub-ohm tanks are likely to suffer leak issues when using a thinner e-liquid than it was built for, and the PG content can be very harsh when inhaled in vast, sub-ohm quantities.For good high-VG e-liquid recommendations, we suggest you check out some of our best shortfill vape juice options.