Semaglutide (Wegovy) injections (2.4 mg per week) are recommended for adults who are overweight or obese and have one or more weight-related health conditions (e.g. high blood pressure, type 2 diabetes, or high cholesterol). It received FDA approval as a weight loss medication in 2021, the first new weight loss medication to gain approval in several years. The most common side effects of Wegovy include: nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, gas, stomach flu, heartburn, and runny nose or sore throat. Additionally, Wegovy presents the same serious weight loss drug side effects including: gastrointestinal side effects, a paralyzed stomach, and other weight loss drugs side effects.