No. According to the Sumatriptan, Naratriptan, and Treximet Pregnancy Registry, there is no association of Imitrex (or Sumatriptan) with [simple_tooltip text=teratogenicity tooltip=A substances capacity to harm or induce abnormalities in an embryo or fetus ] related to significant [simple_tooltip text=congenital disabilities tooltip=A structural or functional abnormality present from birth ] (9).