Yes, you can wash the locs after some time. Try to treat your loc extensions just like your natural locks. The locs with 100% human hair react to shampoo and other haircare products like natural hair. Be mindful that for the initial months, the extension locs go through the budding stage just like the natural locs, so be gentle on your hair. Wash the locs gently and do not pull, tug or yank the locs.