An epigram and a proverb are both short statements that are different from each other in a few ways. The first fact that makes the two different is that an epigram is a witty, satirical and insightful statement said by a particular person, mostly someone who is well-known for their work in their forte; on the other hand, a proverb is a short statement that states a general truth and is not credited to anyone specifically. Another fact is that proverbs have been passed on from one generation to another, whereas, epigrams are found in works of art and literature.