You may fail your DOT physical exam under the following circumstances: • Failure to meet the minimum vision and hearing requirements. • Diabetes that requires insulin treatment without an exemption issued by Federal Motor Carriage Safety - • Administration (FMCSA) • Blood Pressure of 180/110 and above • History of epilepsy • Alcoholism Loss of or diminished use of the limbs not accompanied by a Skills Performance Certificate (SPE) Use of illegal drugs and some prescription medications.