Unfortunately, just like many laser generations before it, despite what you may read in the marketing materials, the PicoSure is not reliable for red ink tattoos. Thats not to say it cant clear SOME of them. It may. But others it really does not budge. It depends truly on exactly which red pigments were used in your ink, and how deep the ink was placed. There is also no way to know ahead of time, other than to try it, and there is no guarantee of your result. I know! You regret the tattoo and now especially the red. Give the PicoSure a try. It certainly is at least as good as other lasers, if not better, but its not a sure thing.