Money line betting is picking who will win the game, regardless of the margin of victory or the run difference between the two teams. The spread, more commonly known as the run line spread in baseball betting, is given to unevenly matched teams. Run line spread is highly dependent on how many runs the winning team wins by. The oddsmakers set the run line spread before the game. And the one with a negative point spread is considered the favorite. For - 1.5 spread, the favored team should win by at least 2 runs for your bet to win. Since the favored team is given a - 1.5 run advantage, the underdog will have a +1.5 run line spread. The underdog team can only lose the game by a single run or straight up win the game. If either of those scenarios happens, you win your bet. Now to answer the question "what pays more: money line or run line spread bets", we'll have to go with run line spreads. The only situation when the money line pays more than the run line spread is when you place a bet on the underdog.