Yes, you can! Make sure your meatloaf has cooled completely, then wrap in a layer of plastic wrap and foil to prevent freezer burn. It will keep frozen for up to 2 months. When you're ready to reheat, allow to thaw in the fridge overnight. Remove the foil and plastic wrap and microwave until heated through. If reheating in the oven, place your thawed meatloaf in a baking dish with a bit of water and cover with foil. Bake at 350 degrees for 20-30 minutes depending on how much you are reheating, until heated through.