Treatment for Uterine Thickening Treatment for thicker uterine lining may vary depending on a woman's age, the severity of her symptoms, and her risk of getting endometrial cancer. The thickening of the uterine lining is not malignant in and of itself, but the danger of it progressing to a precancerous or cancerous stage is considerable. Therefore, any form of treatment must be aimed at reducing this risk. If you are under the age of 45 when your uterus is thickening, your doctor will likely recommend some form of treatment. Uterine artery embolization is becoming a common treatment for abnormal uterine bleeding. It involves injecting tiny particles into the arteries that supply blood to the uterus to reduce the bleeding until it stops naturally. Women can return to normal activity after this treatment. In some cases, women require only one treatment to stop the bleeding permanently. In older women (over 45 years old), hormone therapy is the most common treatment for abnormal uterine bleeding. This type of treatment includes birth control pills, progestin injections, implants, and vaginal rings. Older women are more likely to experience side effects with these forms of medication, so alternative treatments are being looked into as well. One such treatment is uterine fibroid embolization which uses small particles to cut off the blood supply to the tumors blocking the flow of blood to these areas then causing them to shrink over time. Uterine surgery is also an option for treating abnormal uterine bleeding.