Cuticura Mildly Medicated Talcum Powder is rarely bothersome to the skin. In fact, people often use Cuticura Mildly Medicated Talcum Powder to soothe dry or irritated skin. But the powdery mineral can cause problems if it gets under the skin through an open wound. Cuticura Mildly Medicated Talcum Powder should not be applied to the skin when the epidermal barrier is missing or significantly disrupted