There are many causes of atopic dermatitis. One of the strongest risk factors of developing atopic dermatitis is if there is a family history of atopic dermatitis. This is actually a more common skin disease among higher social status groups, and often most prevalent in children. Usually during colder winter months is when people with this condition notice the most problems. This condition impacts the protein in between the cells that make up the top layer of epidermis that is meant to act like a bonding agent. Basically, the skin can become weaker and allow irritants to cause a reaction and inflammation. If left untreated, eczema may become more chronic and result in thicker, tougher patches of skin where the skin is also elevated and discolored.