There is no best time to take Exipure - you can take it whenever suits your daily schedule the best.
Many people prefer to take the pills first thing in the morning with a glass of water. You can also have it after a light meal. If you find it has mild sedative effects, you should take it at night before you go to bed.
A lot of people also take it shortly before working out and find that it greatly benefits them as it provides them with energy and helps them lose more weight than they would've from just a gym workout.
The best time to take Exipure is when it suits you best.