The levels of NT-pro BNP can increase in conditions such as heart failure, asymptomatic left ventricular dysfunction, arterial and pulmonary hypertension, cardiac hypertrophy, valvular heart disease, arrhythmia, and acute coronary syndrome. Along with that, conditions like acute and chronic renal failure, liver cirrhosis, hyperaldosteronism, and Cushing’s syndrome can show increased levels of NT-pro BNP.