Agaricus contains a complex of polysaccharides like beta-glucans that stimulate coordinated defenses against invading pathogens. It activates immune cells and increases protective cytokines. The agaritine it contains also enhances natural killer cell activity against infected or cancerous cells. With gut-reinforcing prebiotics too, Agaricus bolsters immunity on multiple fronts - stimulating defenses, enhancing surveillance, supporting microbiome balance, and protecting against intestinal inflammation.