Rashes from pull-ups can be uncomfortable, but there are ways to deal with them:  Change a dirty pull-up as soon as you can, to avoid leaving your little one sat in damp material.  Be careful when cleaning the area, to prevent any further irritation. Clean with water and a washcloth, and avoid baby wipes with fragrance, lotion, or alcohol.  Don’t put on a new pull-up straight away. Instead, leave the area to dry.  Apply a diaper rash cream. Diaper and pull-up rashes are relatively common, and nothing to be alarmed by. If a rash refuses to fade, starts to blister, or your child develops a fever, they may have an infection. Speak to a medical professional if this occurs.