The main difference between endoscopy and enteroscopy lies in the regions of the digestive tract they explore. Both procedures involve a flexible tube with a camera (endoscope), but endoscopy typically examines the upper gastrointestinal tract, including the esophagus, stomach, and duodenum. On the other hand, enteroscopy is aimed at visualizing the small intestine, which is deeper and more difficult to access within the digestive system. Enteroscopy is often performed when other diagnostic methods like endoscopy or colonoscopy haven't provided clear results or when a problem in the small intestine is suspected.