There are three types of ketamien treatment currently available:
Ketamine infusions: IV infusions are the most common option and tend to provide the quickest results. Ketamine infusions cost $450 to $850 each for depression or other mental health conditions and $650 to $1,500 each for pain management.
Intranasal ketamine: Spravato, an FDA-approved ketamine-derived nasal spray, is often covered by insurance when used for depression. Spravato costs $650 to $1,600 per treatment without insurance or $15 to $120+ per treatment with insurance coverage. Spravato must be self-administered under medical supervision at a healthcare provider's office.
Oral / sublingual ketamine: Oral ketamine costs $35 to $120 per dose and is available in tablet or lozenge form for at-home use. Some patients use oral ketamine to extend the time between maintenance infusions or potentially eliminate the need for them altogether.