Complications of aspiration are uncommon but can occur and may become serious in some cases. Complications can develop during the procedure or recovery. Complications of aspiration are not common but include: Adverse reaction or problems related to sedation or medications, such as an allergic reaction and problems with breathing Bleeding Headache after a lumbar puncture Hypotension (low blood pressure) if a large amount of fluid is removed Infection Nerve injury Pneumothorax (air in the space around the lung that can collapse the lung) from a thoracentesis Pregnancy complications after amniocentesis, such as miscarriage, amniotic fluid leaking, or injury or infection to the baby Re-accumulation of fluid when excessive fluid is withdrawn for a treatment Return of pain or worsening pain Reducing your risk of complications You can reduce the risk of some complications by following your treatment plan and: Following activity, dietary and lifestyle restrictions and recommendations Informing your doctor or radiologist if you are nursing or there is any possibility of pregnancy Notifying your doctor immediately of any concerns, such as bleeding, fever, or increase in pain Taking your medications exactly as directed Telling all members of your care team if you have any allergies