An adjustable bed requires a mattress that easily adjusts along with the bed, so considering the thickness is vital. Other factors that will help decide the thickness of a mattress for an adjustable bed are the physical and health needs of the individual. 8 to 12-inch thickness is generally ideal for different adjustable beds. Zero-G Beds offer customized seven comfort zone natural latex mattress that can have a different number of layers custom-made as per your health conditions. The Seven comfort zone aligns your body, providing exact support to every joint and part of your body.