YES! From Chihuahuas to Malamutes, all dog sizes can use the SafetyChew. We recommend that a dog owner always supervise their dog while they are using the SafetyChew. If your pup is an extreme chewer and usually snacks on Jumbo or Monster bully sticks, the PAWfect solution is coming! We are currently in the process of finalizing the design for the SafetyChew SuperChew. It will use our undefeated patent-pending pin-locking technology, but it will be made of a stronger material and hold larger chews!