It takes only a few days for most patients to return to their normal activities following Lipo 360. Lipo 360 is a typically safe and less invasive procedure than traditional liposuction. Although downtime can vary with any surgical procedure, following post-operative instructions is crucial. In order to achieve the best results and heal quickly, your doctor will provide you with specific instructions. You will need time to heal following your procedure, so avoid strenuous activities and exercise.