Letrozole is a drug that increases the secretion of GnRH in the brain and this causes the release of more FSH and LH. Therefore, it does cause a stimulation in the ovary.
This type of drug, like clomiphene citrate, is used in women with anovulatory problems in both artificial insemination and scheduled intercourse. In both cases, it is necessary to inject Ovitrelle to trigger ovulation.