The Centers for Disease Control and Prevention's website provides recommended and/or required vaccinations for each country. What follows are the specific recommendations for the Amazon region of Ecuador, Peru, and Brazil. For Ecuador, it recommends yellow fever vaccination if you are traveling to the following provinces east of the Andes Mountains: Morona-Santiago, Napo, Orellana, Pastaza, Sucumbios, and Zamora-Chinchipe. There is a relatively low risk of malaria for travel to Ecuador. Talk to your doctor about how you can prevent malaria while traveling. For Peru, it recommends yellow fever vaccination if you are traveling to the following regions: Amazonas, Loreto, Madre de Dios, San Martin, and Ucayali. There is a relatively low risk of malaria for travel to Peru. Talk to your doctor about how you can prevent malaria while traveling. For Brazil, it recommends yellow fever vaccination if you are traveling to the entire states of Acre, Amapá, Amazonas, Distrito Federal (including the capital city of Brasília), Goiás, Maranhão, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Pará, Rondônia, Roraima, and Tocantins, and designated areas of the following states: Bahia, Paraná, Piauí, Rio Grande do Sul, Santa Catarina, and São Paulo. There is a relatively low risk of malaria for travel to the states of Acre, Amapá, Amazonas, Mato Grosso, Maranhaõ, Pará, Rondônia, Roraima, and Tocantins. It is also present in urban areas, including, cities such as Belem, Boa Vista, Macapa, Manaus, Maraba, Porto Velho, and Santarem. Talk to your doctor about how you can prevent malaria while traveling.