Trulicity vs. Ozempic: Clients always compare Trulicity with other medicines. Trulicity and Ozempic, both GLP-1 RAs, treat type 2 diabetes. They have similar mechanisms and purposes; however, they differ in some aspects. They lower HbA1c, a marker of long-term blood sugar management, in clinical trials. Trulicity contains dulaglutide. Ozempic has semaglutide. Trulicity and Ozempic reduce blood sugar in type 2 diabetics. Dosage: Trulicity is a weekly injection pen. Despite its weekly injection, Ozempic is also available as a single-dose pen. Half-life: Ozempic outlasts Trulicity. Ozempic's prolonged half-life may help it work and allow a weekly dosage. Weight Loss: Ozempic has shown higher weight loss than Trulicity in various clinical trials. This weight-loss effect can help overweight or obese type 2 diabetics. Cardiovascular Outcomes: In clinical trials, Trulicity and Ozempic reduced the risk of major adverse cardiovascular events in type 2 diabetics with a history of cardiovascular disease. Side Effects: Trulicity and Ozempic have the potential to cause nausea, vomiting, and diarrhea. Some people may tolerate one drug better than the other. (See the Original Document here) (Medication Guide)