The first step to proper hygiene with your diaper wipe warmer is to unplug the machine. Second, you must remove all of the baby wipes. If it is in need of regular weekly cleaning, then you can wipe the outside with a disinfecting cleaning wipe or a soft cloth and some natural cleaner. After you wipe the outside down make sure to wipe the inside once the machine has cooled down. Allow the machine to dry. Once everything is sanitary and dry replace the moisture cushion or fill the reservoir with water, add fresh diaper wipes, and plug in your machine. Your wipes will be ready to use in no time. If the machine has a little bit of caked-on crud, we recommend that you use a nonabrasive sponge, some elbow grease, and a natural cleaner. As always, make sure the warmer has cooled before cleaning the inside, so you do not get burned.