If you want your office chair to be around for a long time, you need to clean it regularly. How you clean it depends on the material. Mesh-backed chairs are easy to clean with a microfiber cloth. The same goes for leather chairs and seat cushions. For fabric components, use a vacuum to suck up any dust or debris in hard-to-reach areas. As for the metal or aluminum frame, you can simply dust it off with a feather duster or a light cloth.