Over-the-counter (OTC) and prescription medication options can reduce acid reflux symptoms. However, there are options you can also try other than medication. Some of these include: Eat several small meals throughout the day rather than three large meals. This can help keep you from becoming too full, which could exacerbate your symptoms. Consider a weight loss plan if you are overweight. Your doctor can help you create a plan tailored to your goals and health needs. Avoid smoking cigarettes and using other tobacco products. Avoid going to sleep right after dinner. It can be helpful to finish eating about three hours before bedtime so the acid remains in your stomach rather than regurgitate back up.