If you have to apply the cream to an area of skin where you wear makeup or put deodorant on - it is best to put the cream on at least 30 minutes beforehand. Where possible, never put the cream on after makeup or deodorant - always cream at least half an hour first. If you really have to, have a shower or wash any residual makeup and deodorant off first, wait until the area is dry and then put the cream on. This is important because:
You want the cream to be fully absorbed
If there is residual makeup or deodorant on the skin, the transdermal cream formula may bind to these and take them through the skin too.