Sure! Shiatsu massagers can provide a great massage whether you're in bed or not. However, there are a few things to keep in mind when using one in bed. First, make sure that the surface you're placing the massager on is firm and even. This will help ensure that the massager doesn't slip and slide around while in use. Second, be aware of your sheets and blankets. You don't want them to get caught in the massager or interfere with its operation in any way. Lastly, if possible, position yourself so that you can comfortably reach all areas of your body with the massager. This will help you get the most out of your massage session.