Short answer: Yes! Not wrapping your mattress in protective packaging could be one of the biggest moving mistakes you could make. Mattresses are expensive, and not worth the risk of damage. Mattress bags can keep your bed protected from spills and stains when en route to your new place, and free from pests, bed bugs, and mold if you're planning on keeping it in storage for some time. It could be the difference between your mattress lasting for years to come or having to spend the rest of your savings on a new one.