Yes you can….the requirements is a minimum of 80 foot pounds (kinetic energy) is needed for buffalo, giraffe and lion. A 105 foot pounds (kinetic energy) is needed for elephant, rhino and hippo. You would need a heavy fixed two blade broad head that is sharp to the tip to get maximum penetration. Arrow weight should been between 700 to 900 grain. Some Dangerous game do need the required permit for such a hunt.