Liposomes can be both naturally occurring and artificially made. They can form naturally when tissues are disturbed, such as when tissue is damaged and small pieces of the cell membrane become detached. [10] Artificially, liposomes can be prepared by disrupting biological membranes, such as by sonication. [11]  In the lab, scientists can use sonic waves to break apart lipid bilayer membranes into any size liposome they want. [10]