The best AM5 motherboard for future-proofing right now is the ASUS ROG Crosshair X670E Extreme. With its robust 18+2 teamed power stages, elaborate cooling, PCIe 5.0 support, and latest connectivity like WiFi 6E, it's built to handle next-gen AMD CPUs for years to come. The high price tag is worth it for enthusiasts who don't want to compromise.