In April 2004 Juvenon improved the formula of Juvenon Cellular Health Supplement by adding the B vitamin biotin. The amount added is 100 micrograms per tablet, equal to 33% of the Recommended Daily Allowance recommended by the United States Government. Biotin is required in a number of biochemical reactions, including those involving fat and carbohydrate metabolism. It is important for maintaining optimal levels of metabolites utilized for energy production in the mitochondria. It also contributes to maintaining healthy skin, hair and nervous system*.The molecular structure of biotin is similar to that of alpha lipoic acid, one of the principal ingredients in Juvenon Cellular Health Supplement. As a consequence of this structural similarity, an excess of alpha lipoic acid can compete with or displace biotin from its cognate enzyme, according to experimental evidence from cell and animal studies. For this reason, biotin has been added to offset a potential imbalance.