OOS and OOT are both related to quality control and manufacturing processes. OOS stands for "Out of Specification", which means that a product or sample does not meet the pre-defined specification limits or criteria for quality, potency, purity, or any other parameter that is being tested. OOT stands for "Out of Trend", as I mentioned earlier, which refers to a situation where a product or process is not performing as expected or is deviating from its intended or normal performance. Both OOS and OOT are indicators that there may be issues with the manufacturing process, quality control measures, or the product itself. When a sample or product is found to be OOS or OOT, further investigation is typically conducted to identify the cause of the issue, and corrective actions are taken to prevent similar issues in the future.