Under no circumstances should one take alcohol and 5-hydroxy-l-tryptophan capsules at the same time. Alcohol may interact with the active ingredients of the capsules and render them ineffective or even dangerously toxic. As such, you are advised to wait between 6 to 12 hours after swallowing the capsules before indulging in an alcoholic beverage. It would be better, obviously, if you can avoid taking alcohol altogether in the first place.