The platelets enriched in PRP produce growth factors that positively influence proliferation, survival and differentiation of many different cells. This also seems to be true for hair follicle cells. The higher the number of platelets, the higher the concentration of growth factors. The most important growth factors involved in hair follicle formation are probably vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), insulin-related growth factor (IGF)-1 and fibroblast growth factors. These growth factors are involved in stem cell migration, differentiation and proliferation. Additionally, platelets also stimulate fibroblasts and endothelial cells to induce new extracellular matrix deposition and neo-vascularisation respectively. All of this can result in decreased hair loss, prolongs growth phase of the hair cycle, more volume and better hair quality. NOTE: Platelet Rich Plasma Treatment is in the early stages of research for hair restoration and is not meant to replace current proven effective therapies such as DHT blockers and Minoxidil, but it is a promising non-surgical therapeutic option for patients with hair loss.