Anti-obesity medications are a key tool used in our practice to help patients lose weight, and maintain their weight loss. As discussed above, only a 5-10% weight loss helps reverse chronic diseases. By itself, Ozempic (also marketed as Wegovy for weight loss) has a 12% weight loss at the highest dose. Mounjaro (which is being fast-tracked by the FDA for approval for weight loss) has a whopping 22% loss at the highest dose. When coupled with an excellent diet, exercise and behavioral plan, these medications are a key part of the disease-reversing process not only for Diabetes, but for other diseases like Hypertension, High Cholesterol and fatty liver disease. Unfortunately, when not coupled with the other pillars (especially nutrition), these medications can cause real problems as they can completely remove the urge and interest to eat.