It's generally not recommended to sleep with a pearl bracelet on. While sleeping, jewellery can become subject to various forms of stress that can lead to damage over time. It's best to remove pearl jewellery before going to bed and store it properly to ensure its longevity and maintain its beauty. Proper care involves gently wiping the pearls with a soft, damp cloth to remove any oils or residues and storing them in a soft pouch away from other jewellery that could scratch them.