It’s unlikely that a Shingrix injection will cause a rash. But note that an injection site reaction is different from a shingles rash. (See “Injection site reactions” in the “Shingrix side effects” section above.)
A shingles rash, which is caused by shingles itself, is often painful. It commonly appears as blisters around the torso, neck, or face.
People who received Shingrix in clinical studies didn’t report shingles-like rashes.
However, studies did find that some people had shingles-like rashes after receiving the Zostavax shingles vaccine. (Zostavax was an alternative shingles vaccine. But it’s no longer available in the United States. See the “Shingrix vs. Zostavax” section above to learn more.)