No, just the duration of action is longer, 36 hours compared with 4 to 5 hours for sildenafil and vardenafil. This lower strength tadalafil drug is safe and effective for most men with ED. In fact, if your doctor has advised tadalafil 5 mg daily, you can take Modula 5 mg, as it is much cheaper and easily available. By no means, the drug is stronger than sildenafil or vardenafil.