The shelf life of replacement ink cartridges will vary with what you’re currently using, but most original cartridges will last up to 24 months. Compatible cartridges that aren’t made by the manufacturer will typically last up to 36 months. But over time, the ink will dry out and settle inside. This can cause your printer to clog. To keep this from happening, you should print something every couple of weeks so your cartridges stay primed.