No. Opioids like Avinza should not be taken with other pain medications or alcohol. Alcohol suppresses your nervous system, adding to the suppressive effects of Avinza. If you drink alcohol while taking Avinza, you could experience cognitive and coordinative impairment, as well as fatal consequences. The possible interactions are so dangerous that even things with trace amounts of alcohol, like cough syrup, should be avoided when taking this medication.