The amount of time it takes for a mole to fall off after laser removal can vary depending on several factors, including the size and location of the mole, the specific laser used, and the individual’s overall health. In general, the mole or skin lesion may start to look dry and scaly within a few days to a week after the procedure. Over the next several days to weeks, the treated area will heal and the mole or skin lesion will eventually fall off. The exact amount of time it takes for the mole to fall off can vary, but most people notice a noticeable improvement within 2-4 weeks after the procedure.