RADIESSE is FDA-approved to reduce the appearance of moderate to severe facial wrinkles and folds, such as the “parentheses” lines that run from the side of the nose to the corners of the mouth (nasolabial folds). Off-label treatment with RADIESSE can also restore youthful volume to upper and lower cheeks, the chin and jaw line, as well as temples and hands. RADIESSE can also be used to reshape the nose. We find RADIESSE especially beneficial in the lower face, as well as for men and patients aged 40 and above.