Not necessarily. If you’re looking at a lot of text on the screen, a bigger display may make it easier to read. So, if you’re a big role-playing game fan or keep the captioning on at all times (like I do), it could be good for your eyes to increase the size of that text. Ultimately, a bigger TV just bombards your eyeballs with more light for better or worse. If you really want to make the TV easier on your eyes, however, think about adding some backlight to your setup.