On the day of your appointment, arrive fresh-faced and refrain from wearing any makeup. Your provider will then lead you into the treatment room, mark your face, and begin a series of injections. Using a very fine needle, they will inject the gel-like filler into the target areas on your lips. Any discomfort can be managed with the help of a numbing agent or by applying an ice pack after the procedure. Most lip filler appointments typically take around 15 to 20 minutes. You can return home immediately after treatment.