Acetylcysteine has been used as an effective antidote for Paracetamol overdose. It reduces the risk and severity of liver injury after Paracetamol poisoning. If administered within the first eight hours of Paracetamol overdose, Acetylcysteine (N-acetylcysteine) has a nearly 100 percent success rate in avoiding Paracetamol-induced hepatotoxicity.