Cardiovascular diseases (mainlu heart disease and stroke), which were the leading cause of death in 2012 diabetes musculoskeletal disorders (especially osteoarthritis, a highly disabling degenerative disease of the joints) some cancers (including endometrial, breast, ovarian, prostate, liver, gallbladder, kidney and colon) The risk for these diseases increase with increased BMI. Other health consequences are depression, anxiety, gallstones, varicose veins, menstrual abnormalities, hyperlipidaemia, increased morbidity and mortality.