Botox does not cause wrinkles to get worse. When it wears off, you may notice your wrinkles more than you did before Botox. That's because you're comparing your "before" to the relaxed look of Botox. Many people believe that Botox can be used to prevent wrinkles in the skin by relaxing the muscles underneath. These patients believe that if the muscle never contracts the wrinkle will never be created in the first place.