No, Arktivate is made from natural organic sources and is considered pet safe. Our beneficial microbes are also not harmful towards pets, although care should be taken with aquatic animals, such as fishes. We also constantly screen our products through laboratory tests for pathogenic bacteria such as E.Coli, Samonella, etc. As a disclaimer, should your pet ingest significant quantities of Arktivate and show signs of illness or distress, please seek the relevant expert medical attention.