Imiquimod is a topical immune response modifier available by prescription for patient application at home. Imiquimod is approved for use in genital warts but has been used off label in the treatment of non-genital warts. It is felt to work through induction of interferon alpha, a cytokine involved in cell-mediated immunity. Imiquimod is applied anywhere from three nights a week to seven nights a week for a total of eight weeks. Redness is expected, and sometimes swelling and crusting develops requiring temporary discontinuation of Imiquimod.