Since a rune pouch will be lost if you have it in your inventory and then die during PvP combat, some people do have insurance against losing the pouch. If they get a rune pouch note from the Grand Exchange or the Last Man Standing points, and they still have a rune pouch, you can still keep the note. On the off chance that you lose the bag, you can easily redeem the note for another one. The runes inside the bag will be lost, but you will still get to keep the bag.