If you have never taken cell salts (aka tissue salts, Schuessler salts) before, you may want to consider taking Jackson's 12 in 1 Cell Salt Combination first. It is an overall tonic to help naturally improve energy levels and mineral absorption. If you respond well to it then you can start to explore the individual cell salts #1 - 12 for more specific concerns. If you are certain about which particular individual salt you wish to take, then you will be able to follow the directions on the bottle for the standard approach to cell salt dosing. Read about how to get started using cell salts and when to stop taking them Read about when to take a 12 in 1 and when to take a single cell salt