Yes, you can use other detergents in a Bissell carpet cleaner. However, it is important to check the manufacturer's instructions before doing so as some cleaning solutions may not be compatible with your machine. Additionally, make sure that any detergent used is specifically designed for use in a carpet cleaner and follow all safety precautions when using the product. Lastly, always test an inconspicuous area of the carpet first to ensure there are no adverse effects from using an alternative cleaning solution.