A. The most significant difference in preparing these products is that muffins require a batter for production, whereas biscuits require dough. Furthermore, muffins usually have a liner, which you can make from paper, silicone, or other materials. They're also cakey, fluffy, and crumbly in texture. On the other hand, biscuits are often flaky, without a lining, and have a soft golden hue on the sides, but not nearly as golden as muffins.