If the handles are made of standard low-melt plastic, they cannot be autoclaved. There are many different types of plastic that can withstand the autoclave process, though, examples of such include polycarbonate, polypropylene, and acrylics. Look for handles made of these materials if you plan on using an autoclave chamber for sterilization of your new trauma shears. If you are looking for a set that can be safely placed in the autoclave without damage to the handles, specifically look for the world “autoclavable” on the manufacturer description. If they are listed as autoclavable, the maximum temperature will also be specified, and if they are advertised as such but are damaged by the process anyway, you should be eligible to have them replaced at zero cost to you.