After losing out at the science fair, Richard Ebright undertook various experiments and projects. For his eighth grade project, he tried finding the cause of a viral disease that killed nearly all monarch caterpillars every few years. He tried raising caterpillars in the presence of beetles as he thought the disease might have been carried by a beetle. He did not get any results. However, he went ahead and showed that he had tried the experiment, and this time he won.
The next year, his science fair project was to test the theory that viceroy butterflies copied monarchs in order to prevent being eaten by birds. His project was to see whether birds would eat monarchs. He found that a starling would not eat ordinary bird food, but ate all the monarchs it could get. This project was placed first in the zoology division and third overall in the county science fair.
In his second year at high school, he began the research that led to the discovery of an unknown insect hormone. Indirectly, it also led to his new theory on the life of cells. He tried to find the purpose of the twelve tiny gold spots on a monarch pupa. Along with another excellent science student, he built a device which showed that the spots were producing a hormone necessary for the butterfly’s full development. This project won the first place in the county fair and also an entry into the International Science and Engineering Fair, where it was adjudged the third best in zoology.
As a high school junior, he continued his advanced experiments on the monarch pupa. His project won first place at the International Science fair.
In his senior year, he grew cells from a monarch’s wing in a culture and showed that the cells would divide and develop into normal butterfly wing scales only if they were fed the hormone from the gold spots. That project won first place in zoology at the International Fair.
The summer after his freshman year at Harvard, Richard worked on the hormone secreted from the gold spots, and was able to identify the chemical structure of the hormone. During his junior year, he got the idea for his new theory on the life of cells. Along with his room-mate, James R. Wong, he worked on his theory and wrote a paper explaining the same.