In my opinion, the answer is no, except for older men with low-grade tumors that are not very threatening. For the vast majority of men with prostate cancer, early definitive treatment is indicated. Some of the public information about prostate cancer is misleading. It suggests that prostate cancer is a toothless lion, i.e., that more men die with it than of it. There is a difference between a dead man whose prostate is found to contain cancer when it is extensively examined at autopsy and a living man whose cancer has been found because of an elevated PSA or abnormal digital examination. And the younger a man is, the more likely he will benefit from being cured. It is most likely that a clinically detected prostate cancer will progress with time. For example, waiting for a PSA to get up to 6-7 risks a 30% chance that the cancer would have escaped from the prostate at the time of treatment. Currently, there are watchful waiting studies of young men. It is called “active monitoring.” If the PSA rises or repeated biopsies show more cancer or high-grade cancer, then treatment is initiated. The downside of this approach is that for men whose cancer ultimately requires treatment, it is treated at a later time and the repeated biopsies can me it more difficult to perform nerve-sparing surgery.