Journals may apply image integrity checks at any stage in the publication process (submission, before publication or after publication). ... Image integrity screening cannot be expected to uncover all image aberrations, especially in cases with severe misconduct based on an intent to obfuscate information. Conversely, not all image anomalies identified in image screening imply intent to deceive. (Source: STM Working Group recommendations – A2: (1) Scope of journal integrity assessments) Image manipulation may be detected using the software packages that have been employed in the manipulation (e.g. Photoshop). Tools for detecting image manipulation (termed ‘Forensic Droplets’) are available from the Office of Research Integrity website: http://ori.hhs.gov/droplets.