In the past such a suggestion might have caused the raising of many an eyebrow. After all, deodorant was part of the morning routine. It went on after your shower and that was that. As we mentioned earlier however many dermatologists today are adamant that deodorant and antiperspirant works much more effectively when it is applied right before bed time. And just to drive the point home there are several antiperspirants on the market today that state on their labels that the product should be applied before going to sleep. This all being said, there are no should and shouldn'ts when it comes to proper deodorant application - just apply it when it suits you best.