It is possible to appeal a life insurance denial due to drug use. You can typically request a reconsideration or appeal the decision. You can provide additional information, seek a reconsideration, or explore alternative insurance options that may be more lenient regarding your specific circumstances. Consulting with an insurance agent or attorney can help you navigate the process effectively.It is possible to appeal a life insurance denial due to drug use. You can typically request a reconsideration or appeal the decision. You can provide additional information, seek a reconsideration, or explore alternative insurance options that may be more lenient regarding your specific circumstances. Consulting with an insurance agent or attorney can help you navigate the process effectively.