Neuro-Cardio-Facial-Cutaneous Syndromes (NCFC) refer to a group of rare genetic disorders. These conditions often affect multiple parts of the body, including the heart, facial features, skin, and nervous system. Common examples include Noonan Syndrome, LEOPARD Syndrome, and Costello Syndrome. Each one has its own set of characteristics, but they often share some common symptoms like distinctive facial features, heart defects, and developmental delays.