Yes, it is normal for dehumidifiers to make some level of noise during operation. This noise is primarily generated by the fan and the compressor components of the dehumidifier.
While some noise is to be expected, excessively loud or unusual noises can indicate a problem with the dehumidifier and may require attention or maintenance. If you notice any sudden changes in the noise level, it's a good idea to check the unit for any loose components, debris, or signs of wear and tear.