When choosing a hand cream like the Advanced Clinicals Collagen Hand & Body Cream, factors to consider include the fragrance, texture, hydration level, ingredients, skin type compatibility, and additional benefits such as SPF protection. Fragrance preference is subjective but can impact overall enjoyment of the product. Texture should be smooth and easily absorbed. Hydration level should be sufficient for dry or cracked skin. The presence of ingredients like aloe vera, green tea, and shea butter can enhance the moisturizing properties. SPF protection is important if daily sun exposure is a concern to prevent skin damage.