Radiesse has a excellent safety record which is comparable with other premium dermal fillers. Thankfully, side effects and complications are rare in the hands of a skilled practitioner. As such, it is only safe and effective when it is delivered in a clinical setting by a qualified and experienced aesthetic doctor. Injection of Radiesse, like any dermal filler, carries the general risk of bruising, infection, lumps, asymmetry or even scarring. These risks can be greatly reduced by using the correct technique and practices. Incorrect placement of the filler can also carry grave consequences. This includes lumps, chronic inflammatory reactions or in the worst case scenarios it can get into blood vessels and cause skin death or even blindness. Unlike hyaluronic acid dermal fillers, Radiesse can not be dissolved in case of an emergency or complications.