It can be difficult to tell whether your stomach pain is serious, so if you’re unsure, then you should consider it an emergency and go to the ER. And if any of the following conditions are a concern along with the stomach pain, then you should absolutely seek ER care: - Chest tightness and upper abdominal pain - You had recent abdominal surgery or an endoscopy/colonoscopy - You have a history of gastric bypass surgery, heart attacks, stroke, or heart disease - You are bleeding and are pregnant - You are vomiting blood - You are experiencing blood with your bowel movements - You have a high fever - You are having difficulty breathing or chest pain - You had severe, sudden-onset abdominal pain If you are experiencing any of the conditions above, then you must call 911 and seek emergency care. Only emergency care is properly equipped to handle major abdominal pain and the symptoms associated with it.