For a female, we see age-related changes in testosterone, estrogen, and progesterone.  Testosterone levels peak between 18-24 years of age and then decline until menopause, which happens on average at age 51 (of course it can be earlier or later given family history). Menopause is a normal event that results in an abrupt decline in estrogen production. As estrogen levels drop, we see hot flashes, night sweats, changes in periods (they become erratic and can be more or less frequent initially, and then stop as estrogen continues to drop). As testosterone drops, we see the same symptoms we see in andropause.