Chemical-based descalers are specifically designed to eliminate mineral build-up and are highly effective against minerals, but not against other residues and contaminants. On the other hand, vinegar has cleansing properties that can eliminate mineral build-up as well as other contaminants. This makes the vinegar more versatile than chemical-based descalers. Furthermore, the natural composition of vinegar means no chemical agents are involved, making it a safer option to use. The cost difference between the two is minimal, with vinegar being approximately 10% cheaper.