As you have already learned, PQQ protects the mitochondria, which are responsible for producing energy. In general, the mitochondria in our body are not very well protected and are exposed to more immense stress than the other cell structures.
It is important to note that almost the entire bioenergy of the human organism is generated in mitochondria.
Since almost all bodily functions and organs are dependent on this energy supplier, a failure can have drastic consequences. PQQ helps in the formation of new mitochondria, which are often larger and have a higher mass. An undersupply of PQQ can impair the function of the immune system, with white blood cells losing their ability to respond appropriately. Visible symptoms of PQQ deficiency can include hair loss, brittle skin, poor collagen synthesis or growth failure.