Most CRMs will have a CPQ function as part of their overall solution, the most famous being Salesforce CPQ. This means that a rep can create a proposal and generate a quote without ever leaving the CRM. However, there are also a lot of standalone solutions that integrate with your CRM, meaning that a salesperson would still be able to complete most, if not all, of the sales process without setting foot in your CRM. In short, you have options.