It depends on the surgery and the medications, so talk to your doctor and the surgeon to see what you can take in the weeks leading up to the surgery. For most surgeries, you want to stop blood thinners, aspirin, vitamin E, fish oil, any homeopathic medication at least 2 weeks before the surgery. Tylenol is typically the only thing you can take within 2 weeks of a surgery, but it depends on the procedure and your personal situation.