Yes. A significantly different job cannot be done with the same blade, and anyone who engages in a lot of this type of work will have to learn about and purchase a variety of blades. Blades are cheap relative to the machines themselves, especially for devices that take shorter blades.
If one is looking to cut harder wood or to cut materials such as plastic, blades with hook teeth are a good idea. Hook teeth are capable of cutting hard plastic precisely. For cutting a copper pipe or some other soft metal object, one might use hook teeth. Harder metals can certainly be cut with some band saws, and for these cuts, one wants to use a raker blade or a wavy blade. Many machines are incompatible with many lengths of blades.