Two famous murder investigations that were significantly aided by DNA fingerprinting are the following: O.J. Simpson Trial (1995): The trial of former American football player O.J. Simpson for the murders of his ex-wife Nicole Brown Simpson and her friend Ronald Goldman is notable for its use of DNA fingerprinting evidence. DNA analysis conducted on blood samples found at the crime scene, including bloodstains on clothing and the infamous bloody glove, provided crucial evidence linking O.J. Simpson to the murders. The DNA profiles obtained from the samples matched O.J. Simpson's DNA, which played a pivotal role in the prosecution's case and ultimately contributed to his acquittal. Colin Pitchfork Case (1988): The Colin Pitchfork case, which occurred in the United Kingdom, marked the first time DNA fingerprinting was used to solve a murder investigation. In 1986 and 1987, two young girls were raped and murdered in Leicestershire. DNA evidence recovered from the crime scenes was compared with DNA samples obtained from suspects. The groundbreaking DNA fingerprinting technique, developed by geneticist Sir Alec Jeffreys, played a crucial role in identifying the perpetrator. Colin Pitchfork became the first person to be convicted of murder based on DNA fingerprinting evidence in 1988, leading to a significant advancement in forensic science. These cases highlight the pivotal role that DNA fingerprinting played in providing conclusive evidence, identifying the perpetrators, and influencing the outcomes of these high-profile murder investigations. DNA fingerprinting has since become an essential tool in forensic investigations worldwide, aiding in solving numerous crimes and delivering justice.