No, latex mattress toppers are not toxic (on top of that, it is dust mite resistant). Latex is a natural material made from rubber trees, and it contains proteins that are capable of triggering allergic reactions in some people. To avoid this type of reaction, you should look for mattress toppers that are made with natural rubber or man-made polyurethane. If you're uncertain whether a mattress topper is made from natural latex, you should avoid it. Read more