Postpartum depression is a common yet often overlooked condition that affects many new mothers. The hormonal changes and emotional challenges during the postpartum period can lead to significant distress. Ketamine-assisted therapy holds promise in supporting maternal mental health by providing rapid relief from postpartum depression symptoms. With its ability to enhance neuroplasticity and restore emotional balance, ketamine can help new mothers navigate this vulnerable period, fostering a healthier bond with their babies and a smoother transition into motherhood.