Yes, but youâ€ll have to be careful with it. The harsh detergents used in a washing machine can deteriorate the quality of your tablecloth, shred it, or peel off the patterned layer. To avoid this, use only a small amount of mild-acting detergent. Steer clear of any bleaching or over-the-top drying/wringing. This can cause your tablecloth to fade in color, tear, crinkle, have loose threads, or shrink in size. Instead, resort to a gentle cycle in the washing machine, and let it clean separately. After, let it air dry on a washing line.