Every woman’s experience is different. Since the breast tissue is compressed during a mammogram, it is normal to feel some mild discomfort. The amount of discomfort will vary depending on a number of factors, including the sensitivity of your breasts and where you are in your menstrual cycle. If you experience significant discomfort, let your mammography technologist know. You can also talk with your doctor about reducing discomfort during future mammograms by taking a dose of an anti-inflammatory medication or a pain reliever in the hours before your scan.