Chemical peels and microdermabrasion are both popular skincare treatments, but they differ in their mechanisms and results: Chemical Peels: These treatments involve the application of a chemical solution to exfoliate the skin. They are suitable for addressing a larger range of skin issues since they can deliver more obvious and long-lasting improvements. Microdermabrasion: Microdermabrasion uses mechanical exfoliation to remove the top layer of skin. While it can improve skin texture and appearance, it may require more sessions for comparable results to some chemical peels.