Adderall and Ritalin are prescription drugs with the strongest nootropic effects, but they also have a number of side effects. Adderall contains amphetamines and Ritalin contains methylphenidate. Some of the most common side effects of these nootropics include anxiety, high blood pressure, low sex drive, and sweating. If used excessively, they can lead to seizures, hallucinations, heart attacks, and psychosis.