Use Avedana Cool Hot Ice (Topical) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.Use exactly as directed on the label, or as prescribed by your doctor. Do not take by mouth. Topical medicine is for use only on the skin. Do not use on open wounds, damaged skin, broken skin, or irritated skin. Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using exactly as directed on the label, or as prescribed by your doctor. Wash your hands before and after applying this medicine. Use a mild soap to clean the skin area to be treated. Do not cover treated skin with a bandage or use a heating pad unless your doctor tells you to. Menthol can cause a cold or burning sensation, which is usually mild and should lessen over time with continued use. If this sensation causes significant discomfort, wash the skin with soap and water. Stop using this medicine and call your doctor if your symptoms do not improve after 7 days, or if your symptoms get better and then come back in a few days. Store tightly closed at cool room temperature away from moisture and heat. Protect from direct sunlight and keep away from open flame or high heat.