To begin with, we hasten to please you. Saxenda stopped working is a problem faced by 1-2% of the total number of users.  Nevertheless, some features of the organism can bring the Saxenda plateau closer. These include a genetic predisposition to excess weight. People with this feature may develop resistance to liraglutide, which will reduce its effectiveness. Also, the body can become tolerant to liraglutide, which is why the brain gets used to its effects and “turns off” the receptors that were responsible for the state of satiety. At the same time, you should know that most cases when users complain that the Saxenda pen not working anymore are caused not by the medicine itself but by a violation of the nutrition plan, as well as a decrease in physical activity.