While there may not be any specific danger associated with mixing psilocybin with these types of medications, it is generally advised against due to its potential impact on the quality of the psychedelic experience. The use of SSRIs and SNRIs, for instance, can lead to a muted psychedelic experience for many individuals, even several weeks after they have stopped taking them. However, this effect is not universal, and some people have reported intense psychedelic experiences shortly after discontinuing or even while taking these medications. Therefore, it is difficult to predict your personal experience. If you wish to taper off these medications, it is recommended to do so under the guidance of a medical professional. At our retreat, we aim to educate guests about the effects of psilocybin, guide them through their psilocybin experiences, and teach them mushroom cultivation skills. We discourage putting too much pressure on oneself to quickly taper off medication for a specific intensity of experience at the retreat, as it may be counterproductive. Instead, we encourage self-kindness, taking things at your own pace, and finding a therapist who supports psychedelic therapy when you return home.