Loneliness may be a symptom or feeling experienced by those diagnosed with depression or anxiety, but the relationship is not a simple causal one. Feeling depressed, anxious, or lonely sometimes is a normal part of being human–we all need other people in our lives and social connection to pursue meaningful work, play, and love. But sometimes, when loneliness persists and won’t let go or makes it difficult to function in your day-to-day life, it may be signaling deeper issues that a trusted mental health professional can help address.