Although there haven’t been any long-term scientific studies of tolerance to these herbal medicines, there has so far been little evidence of dangers associated with them, as long as they are being taken in moderation with due regard to the few known contraindications (see more about that in the FAQ section below). Overdosing with even the mildest medication always carries some risks, so as long as you make sure you are taking only the recommended dosage each day, there are no dangers in using Calmanervin every day if your levels of stress or anxiety are making you uncomfortable.