Thanks for reaching out Rob! Even if 22 WMR (aka 22 Magnum) *could* chamber in a 22 LR firearm, it would only succeed at destroying it. Long story short: you only want 22 LR for a 1911-22. I recommend sticking to copper-plated bullets, as these will help to decelerate lead fouling inside a semi-automatic's barrel. I also recommend higher-velocity ammo (i.e. muzzle velocity in excess of ~1,130 fps), as it should generate sufficient chamber pressure to fully cycle a semi-auto. I further recommend higher-quality American-made 22 LR, as even a well-made 22 LR semi-auto pistol is a somewhat finnicky machine. My absolute all-time favorite 22 LR for a semi-auto pistol is CCI Mini-Mag. I especially prefer the round nose bullet, as I've found that profile lends itself to more reliable feeding. I'm happy to say we have my favorite in stock right now: https://www.luckygunner.com/22-lr-40-gr-cprn-0030-cci-100-round
Please let me know if you have any other questions!