No, the plugin will not support breadcrumb. If you use theme's default setup, it will not work in many cases. In case, if you use Yoast breadcrumb then the support team will ask you to order custom development services for doing that. In our opinion, this is cheating bt selling the plugin for free one-year update and support and ask to pay for breadcrumb integration. In fact, most custom post types plugin in WordPress allow you to create post type archives so that it will show up in default breadcrumb. However, CM Tooltip plugin does not have an option to include glossary index in the breadcrumb trail.