Physiologic problems of the brain corpus callosum can lead to a type of abnormality known as hypoplasia or agenesis. This refers to an abnormal brain malformation that leads to the absence of the callosum, either partially or totally. While it is generally considered a rare disease, it can occur in 3-7 individuals in every 1000 births. While the cause of such abnormality is unknown, it is considered to be non-genetic and sporadic. Agenesis leads to malformations in certain callosum parts, but on the whole, is not considered to be fatal and is often benign. Since corpus callosum function includes cognitive behaviour, patients suffering from this abnormality will face certain issues like socializing and problem-solving difficulties. The corpus callosum connects the two hemispheres of our brain so due to its absence one might also face seizures.