Collagen really makes you poop! The protein collagen has three essential amino acids which lowers constipation, helps with leaky intestinal syndrome, and even reduces diarrhea. Glycine, glutamine, and proline are the three amino acids within collagen. Both of them work together to reinforce your intestine. Many people wonder if over-protein will cause constipation. The easy response is “yes” and several other stomach issues. The perfect protein you can eat each day depends on how much you weigh. Dietary consumption is 0.36 grams per pound. That’s about 56 grams of protein a day for men and 46 grams a day for women.