Ans: The study identified gastrointestinal disturbances as one of the main safety concerns of compounded semaglutide and tirzepatide. Participants reported experiencing more pronounced gastrointestinal side effects compared to when the medications were used individually. Additionally, there were reports of cardiovascular issues, such as fluctuations in blood pressure and heart palpitations. The link between these cardiovascular events and compounded drugs requires further investigation to determine potential risks.