Certainly. In fact, this is expected.
A business plan is best viewed as a living document that should grow and evolve with your company. Markets shift. Public interest goes in new directions. New competitors and business opportunities may arise.
As your business grows, you’ll need to shift your focus or pivot your business model to accommodate for those changes. Your business plan should evolve with you in order to best reflect the position that your organization needs to take in order to remain profitable.