Spray primer makeup is a great way to make your skin look smoother and more even. Spray primer makeup can also help cover up blemishes and other imperfections in the skin. You can use spray primer makeup on its own or as a base for your normal foundation. To apply spray primer, first, shake the bottle well to mix the ingredients inside. Hold the bottle about 12 inches away from your face and spray in an even, sweeping motion across your face.