Yes - but please read these cooking tips first! In fact, the updated recipe photos you see in this post were taken one of the times I substituted Israeli couscous for quinoa -- with great success! I offer this substitution with the caveat that you must realize it is a different type of grain and you'll likely need to adjust accordingly. I usually make this dish with couscous in my Ninja Foodi XL 8-Quart Deluxe 9-in-1 pressure cooker. 1: I use *slightly less* couscous than the amount of quinoa that the recipe calls for -- try 3/4 cup instead of one cup. 2: Make sure you are using a dry measuring cup for dry ingredients, and a liquid measuring cup when measuring the chicken broth. 3: Try using one pound of chicken - not a pound and a half. I have made this several times now with regular couscous and with larger Israeli couscous and I have NEVER once received a BURN notice.