Yes, even if you don't itemize there are numerous benefits to the Giving Account ranging from streamlined recordkeeping to potential investment growth to involving your family.
However, there are other financial benefits too. By donating appreciated assets like stock directly to Fidelity Charitable, you can minimize the capital gains tax allowing you to potentially give more to charity.
You can also use a "bunching" approach that may help you exceed the standard deduction. The "bunching" strategy allows you to frontload multiple years of charitable giving in one year to potentially surpass the itemization threshold, making it possible to obtain a tax deduction, and then you can take the standard deduction in the off years.
This can also be an impactful strategy for donors experiencing a high-income year or preparing for retirement, since you can maximize your tax benefits when you need it while creating a ready reserve to support charities over time.