PCI Express (PCIe) slots are backward compatible, so you can always install modern graphics cards into a motherboard from many generations ago. Any graphics card, from PCIe 1.0a to PCIe 4.0, will work on your motherboard, irrespective of your specs. The only downside of using high-end, powerful cards on slots older than PCIe 3.0 is that you'll be leaving a lot of performance on the table.