There are different factors that tend to have an effect on the weight of the heart in female and male bodies. For example, the size of the women’s hearts tends to be smaller when compared to the size of the heart in male bodies. This leads to the deduction that the weight of the heart in the case of men will be more than the weight of the heart in women. On an average scale, the weight of heart in grams in men is found to be somewhere around 315 gms in total. In comparison to that, the average weight of the female heart is found to be somewhere around 265 gms in total. As you can see, there is a pretty vast difference in the weights of both the male and female hearts.