Regulatory challenges in cold chain logistics include complying with strict temperature control standards, maintaining detailed documentation, and adhering to guidelines set by various authorities such as the FDA, WHO, and EMA. These regulations are designed to ensure the safety and efficacy of temperature-sensitive products, such as pharmaceuticals and perishable foods like ice cream, dairy, meat, etc. Companies must implement robust compliance programs, regular audits, and thorough training for staff to navigate these regulatory requirements effectively​.