Tenderness or pain in the breast region is another common symptom of gynecomastia to watch for. Discomfort usually occurs in both breasts, but it may initially start on one side only. The pain can range from mild sensitivity to more severe aches. Many men describe it as a swollen, tightened, or burning sensation. The discomfort may be concentrated around the nipples specifically. Pain often increases with touch, movement, or pressure on the breasts. However, the tenderness can also flare up on its own without any stimulation.