Milkweeds are toxic for small children, pets, and other animals. The plant contains cardiac glycosides that impair the function of the heart. Other glycosides and resinoids impact various systems within the body (respiratory, digestive, nervous.) Caution should be used when planting Milkweeds around grazing animals, pets that tend to chew and nip on plants, and small children who put the plant in their mouths. The milky sap also irritates the skin causing rashes and itching.