Key perks include Painkiller, Dorph-head, and Comeback Kid for health. Wrecking Ball, Breakthrough, and Die! Die! Die! enhance combat. Adrenaline Rush and Juggernaut boost survivability.Quake is great for area damage. In Reflexes, focus on Dash and Mad Dash for mobility. Technical Ability perks like Health Freak and All Things Cyber improve cyberware and healing.