Hello, Thanks for choosing health care magic for posting your query. I have gone through your question in detail and I can understand what you are going through. You are already on escitalopram and bupropion and citalopram i.e celexa has almost similar profile of activity as your escitalopram i.e. Lexapro. So you wont be benefitted much by the addition of this new medication that you are thinking about. Talking about augmenting your present therapy, adding lithium or an antipsychotic like quetiapine, olanzapine would be more effective. Also try augmenting your therapy with cognitive behavioural therapy. That has shown good results. Hope I am able to answer your concerns. If you have any further query, I would be glad to help you. In future if you wish to contact me directly, you can use the below mentioned link: bit.ly/dr-srikanth-reddy Wish you good health, Dr. Srikanth Reddy M.D.