There are many man-made waterproof fabrics, but the vast majority of motorcycle rain gear rely on a combination of Nylon and PVC materials. Gore-tex is also another popular waterproofing material, and Gore-Tex motorcycle rain gear is probably the best stuff you can buy. Leather jackets and pants that have been treated properly are quite good at keeping the rain out. Waxed cotton and leathers are also quite good, but they’re not nearly as good as man-made fabrics at keeping the elements out – they’re not very breathable either. For the best results, stick with man-made fibers and fabrics. Even then, a man-made waterproof fabric is only as good as the quality of the stitching and fastenings that hold it together. Before you buy a product, try and take a look at the stitching, gluing, and what protection the joins have.