The beginning of action of oxycodone is determined by the medication’s formulation. Immediate-release oxycodone often begins to work after 10 to 30 minutes of administration, with peak effects occurring within 1 to 2 hours. The effects of immediate-release oxycodone last 4 to 6 hours on average. In contrast, extended-release oxycodone is intended to give pain relief over a longer length of time. The effects of extended-release oxycodone may take longer to kick in, often taking 1 to 2 hours. The effects of extended-release oxycodone, on the other hand, might linger for up to 12 hours. It is important to note that oxycodone’s onset and duration of effect can vary based on individual characteristics such as the person’s metabolism, medical condition, and other medications they are taking. As a result, it is critical to follow your healthcare provider’s oxycodone administration instructions and to report any changes in your pain levels or response to the prescription. The time it takes for oxycodone to take effect varies depending on the formulation. When taking immediate-release oxycodone, the medicine usually starts working within 10 to 30 minutes, with peak effects happening within 1 to 2 hours. The effects of immediate-release oxycodone last 4 to 6 hours on average. In contrast, extended-release oxycodone is intended to give pain relief over a longer length of time. The medicine is gradually delivered over a 12-hour or longer period, providing consistent pain relief throughout the day. Extended-release oxycodone often has a slower beginning of action than immediate-release oxycodone, with peak effects occurring 3 to 4 hours after the initial dose. It is crucial to note that the beginning of action for oxycodone can be influenced by a variety of factors, including the individual’s metabolism, the medication’s dose, and whether the medication is taken with food or on an empty stomach. Your healthcare practitioner may provide you more precise information about how long it may take for oxycodone to start working for you.