Radiesse can be difficult to dissolve, but there are options available. The first step in dissolving Radiesse is to have a consultation with a board-certified dermatologist to determine if you are a candidate. If it is determined that you are a candidate, then sodium thiosulfate can be injected into the area to dilute the Radiesse and thin it out. This can be done with pressure to help break up the nodules. This is an expert injection technique that varies in injection technique and dosage. Dr. Cameron Rokhsar has had success dissolving Radiesse with Sodium Thiosulfate in many patients. It is important to keep in mind that Radiesse will dissolve over time, but this may take 12-18 months. surgical removal should only be reserved as an option of last resort. It is important to have any procedures performed by a board-certified dermatologist with experience in injectables to minimize the risk of complications. It is also worth noting that Juvederm or Restylane are alternative skin fillers to Radiesse, made of a hyaluronic acid gel that mimics your body’s naturally-occurring hyaluronic acid. If you are considering a filler and are concerned about the potential need for reversal, it may be worth discussing Juvederm or Restylane as an alternative with your board-certified dermatologist.