The role of sisA in germline sex determination is likely to be conserved across different Drosophila species and possibly other insect taxa. The sisA gene is highly conserved among Drosophila species, indicating its importance in fundamental biological processes. While specific studies on sisA in germline sex determination in other insect taxa are limited, the conservation of key sex determination pathways and genes across insects suggests that sisA may play a similar role in regulating Sxl expression in the germline of other insect species. Comparative genomic and functional studies across different insect taxa would provide more insights into the conservation of sisA's role in germline sex determination.