The microbes (bacteria and viruses) related to Influenza A/B, Covid-19, and Strep Throat (Strep A) produce many overlapping symptoms making it impossible to confirm a diagnosis and determine the appropriate course of treatment without first testing. Diagnosing a respiratory virus or bacterial infection in the throat is important because it may enable a doctor to prescribe treatments that can both reduce the severity of symptoms the duration of illness. Influenza A or B, COVID-19, and Strep A confirmed by testing supports the optimal prescribing of medication, which shorten the duration and severity of symptoms, and reduce complications and likelihood of spreading the illness to others.