Both the machines are some of the best among all the embroidery machines. However, the Brother 800 is exclusively for embroidering and Brother SE600 is for both sewing and embroidering. Moreover, the embroidery area is expansive in the PE800 as compare to SE600 which has an embroidery era of 4"x4". Plus the features of PE 800 are exclusively for embroidering purpose and therefore it has more embroidering features as compared to the Brother 600 which has features for both sewing and embroidering and therefore, it has less embroidering features.