Of course. As I mentioned, I combine it with morning affirmations. Those pump me up for the day ahead, while the pillow manifestations help me reach my goals in life. In the end, do what feels natural to you. If you feel more confident when you send your message to the Universe several times a day, do that. If you want to just sleep on it, that works as well. As long as you stay positive and don't stress yourself, you'll see wonderful results.