It's possible that, for a short time after receiving Restylane lip treatment, you may have some noticeable swelling. This is in part due to minor inflammation resulting from injections. Restylane also has a high concentration of hyaluronic acid, a naturally-occurring substance that brings water molecules into the target area. In the case of the lips, the target area is small enough that some puffiness may occur. This usually subsides after a few days. If swelling persists, you can contact our office for a brief treatment that can help resolve it more quickly.