The Best 10 eCommerce Niches in 2023 2- Pet Products/Services. The pet owners' niche is a profitable business. ... 4- Eco-friendly/Organic Products. This can be a little broad and can be used in anything. ... 5- Online Courses. ... 6- Re-commerce. ... 7- Fitness & Gym Appliances. ... 8- Jewelry. ... 9- Home Decor. Jan 17, 2023