It is possible to inject interferon beta-1a from home. There are three different syringe options Rebif prefilled syringe, Rebiject II auto injector and Rebif Rebidose auto injector. You should only use Rebif prefilled syringe and Rebiject II auto injector after proper training from a medical professional. Interferon injectables are usually stored in the refrigerator at 2 to 8°C. Recommended preventive measures against injection site reactions include: Remove the pre-filled syringe from the refrigerator approximately 30 minutes before administration and allow it to warm to room temperature. Wash hands thoroughly before injecting. Thoroughly clean the skin at the injection site. Soap and water are less irritating to the skin than alcohol swabs. If alcohol swabs are used (e.g., when travelling or in hospital), allow the skin to dry for at least 60 seconds after use. Change the injection site regularly Cool swellings at the injection site with a cold compress. Treat swellings that last longer than 1 day with heat Treat the rash with ointments containing anti-allergic substances (antihistamines) such as diphenhydramine (Dermodrin or Benadryl ointment), hydrocortisone cream or substances from the witch hazel plant.