Yes! You can most definitely use bone-in turkey breast for this air fryer recipe. The most important thing to consider when using bone-in turkey breast is that the meat must fit inside your air fryer without blocking any of the airflow. As long as the meat fits inside of your cooker it's not going to be a problem. Be sure that when you insert a thermometer it gets close to the bone in the thickest part of the meat but does not actually touch the bone which will give you an inaccurate reading.