Cold sores can be transmitted to the genital area. Cold sores are usually associated with HSV1, while genital herpes is usually associated with HSV2. However, either strain of the virus can affect both the mouth and the genitals. If someone with a history of cold sores performs oral sex on a partner, it is possible to transmit the virus to their partner’s genitals. While transmission is most likely to occur while a cold sore is actively present, it may still be possible to spread the virus while it is dormant. If this is of concern, antiviral medications such as Acyclovir (Zovirax), Famciclovir (Famvir) or Valacyclovir (Valtrex) taken on a daily basis may help reduce the risk of transmission.