Integration and Differentiation are the two most important parts of calculus. On the other hand, it's hard to tell the difference between differentiation and integration. Many students and even professors don't understand the difference. Differentiation is different from integration in that it is used to find instant rates of change and the slope of a curve. Differentiation is used to find the instant rates of change from one point to another and to figure out the gradient of a curve. Integration, on the other hand, is used to find the area under a curve. As you can see, differentiation and integration are opposites in terms of what they mean in math.