Yes. You can prepare this gluten free slow cooker meatloaf the day before and then after it has cooled store it in our refrigerator. My husband actually prefers day old meatloaf to fresh. He likes it reheated or cold on a sandwich. To reheat you can microwave the meatloaf. Sprinkle some water over the meatloaf and then place a very wet paper towel over the meatloaf before heating. This will keep your meatloaf from drying out while you are reheating it.