If you have just had an epidural steroid injection, there are certain activities that you should avoid for the first 24-48 hours to ensure that the injection is effective and that you do not experience any complications. These activities include strenuous activity, bending, lifting, and twisting. You should also avoid sitting and lying flat on your back for prolonged periods. Anything that puts pressure on the injection site should be avoided, and you should take it easy for the first day or two after the procedure.