Restylane injectable  offers multiple benefits, but it doesn’t have many adverse side effects. Even then, the side effects are usually mild, temporary, and restricted to the area immediately surrounding the injected area. These include the following: - Pain or soreness - Redness - Inflammation - Swelling - Itching - Bruising When injected into your lips, these side effects should recede within a week; otherwise, you can expect the side effects to fade within 72 hours.