Hi, Vyvanse contains lisdexamfetamine that belongs to the group of medications known as stimulants is used in the treatment of attention deficit hyperactivity disorder or ADHD and sometimes binge eating disorder. It may cause excessive sweating or aggravate the production of acnes. If someone is already prone to acne, then Vyvanse can make it worse. Acnes are noticed among people who consume this medication, especially in case of females, 18-29 years old, have been consuming Vyvanse for one to six months according to some researches. Again, excessive sweating is a common side effect of Vyvanse. You should not stop taking this medication without consulting your doctor. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician