The distance from Hartford, CT, to Boston, MA, is approximately 100 miles (160 kilometers) by road. The actual travel time can vary depending on traffic conditions, the route taken, and the mode of transportation. Generally, it takes around 1.5 to 2.5 hours to drive from Hartford to Boston, depending on the traffic. It is worth noting that travel times can be longer during peak hours or on weekends, so it is advisable to plan your trip accordingly.