The strength and efficiency of a Nautilus player may be judged with his ability to land his hooks and pull enemies. Hence, it is important to practice not missing your hook. The more you miss it, the more you’re losing opportunities to get a kill or a lead. To secure a kill with your hook, work around your space. Think of the best position that will grant you a better view and sight to your target. If there is something that may block your hook like a minion, try to reposition and find a better spot. Next, observe the slightest details in their movement, the direction they are taking for an instance and you might even gain information that is useful in predicting their next move.
If you are not confident with your hook, try to close the gap and place yourself near your target as it is harder to miss your hook if you’re in front of them. You may also commence your combo by rooting them with your passive, Staggering Blow before using Dredge Line to completely immobilize them.
But most importantly, do not throw hooks randomly and impulsively. Only use your hook if you are certain that you’ll hit an enemy.