Even though Latisse is not tightly regulated by the FDA or the Drug Enforcement Administration (DEA), there are some potential side effects as well as medication and illness reactions to be aware of, such as: - Using more than one medication with the same active ingredient (bimatoprost ophthalmic solution) can cause a reaction between the medications - Reducing intraocular pressure can mask glaucoma symptoms, which may lead to nerve damage even without high eye pressure - Latisse can exacerbate preexisting intraocular inflammation (such as from uveitis) if used in the same area - Regular use of Latisse can cause eye irritation or dry eyes, which may lead to other visual complications - Macular edema (buildup of fluid in the macula) - Changes to iris pigmentation