With a population of approximately 27,000, the small city of Colonia del Sacramento is among one of the oldest and quaintest communities in the Southern Cone of South America. About a 112-mile (181-kilometer) car ride from Montevideo, Colonia is a smart location for car rentals in Uruguay due to its appealing geography and major historical appeal. Founded along the Río de la Plata, the lad-back community directly faces the Argentine capital of Buenos Aires for some car rental adventures in Argentina. What’s more, it’s historic quarter is also a UNESCO World Heritage Site while the modern part of the city manufactures textiles and has a free trade zone. If you're pumped to start exploring, simply refer to our search engine located at the top of the page to start comparing the best rental rates on the market!