Cozaar (Losartan) typically shows its effects within 3 to 6 weeks of consistent use. However, some individuals might experience improvements in blood pressure sooner. It’s important to continue taking the medication as prescribed, even if immediate changes aren’t noticed, as it may take time for Cozaar to reach its full therapeutic potential in regulating blood pressure. Regular monitoring by a healthcare provider is essential to assess its effectiveness and make any necessary adjustments.