The Microchanneling solutions are used with shallow depth needling (aka cosmetic depths 0.25mm-0.3mm) or with nano cartridges. They have less base Growth Factor media, but also have two additional recombinant protein molecules added to target three skin concerns (aging, pigment, acne). The Microneedling solution has the highest dose of the Growth Factor media and is ideal when you microneedle at a medical depth of 0.5mm and up.