Pros: You can carry and use a waterless hand sanitizer anywhere, It kills 99.9% germs present on your hands, you don't have to rely on water use. Cons: Handrubs are ineffective against grime, weakens the immune system, and induces the growth of resistant germs. Swallowing an alcohol-based hand sanitizer causes alcohol poisoning. According to the US Poison Control, there have been 85000 cases of alcohol poisoning among children from 2012-2015.