Assuming you're talking about a house you already own:
It depends. In some cases, yes, renovating a house can be profitable. For example, if your home is in an area with rapidly increasing property values, or if you make strategic renovations that appeal to buyers in your target market, you could see a significant return on your investment. However, in other cases it may not be worth it financially to renovate your home. For instance, if property values in your area are stagnant or declining, or if the cost of the renovations would exceed the amount you could realistically hope to recoup by selling the property, then it probably wouldn't make financial sense to go ahead with the project.
Of course there are other factors to consider beyond just pure financial gain when deciding whether or not to renovate your home. Sometimes people choose to renovate for personal reasons regardless of whether or not it will increase the value of their property - for example, they may want to update an outdated kitchen or bathroom for their own enjoyment even if it won't add much (or anything) to the resale value of their home. Ultimately, whether or not renovating is worth it is a decision that each individual homeowner will have to make based on their own unique circumstances and goals.