Inbreeding rabbits can be a risky practice and is generally not recommended. Inbreeding increases the chance of genetic disorders, birth defects, and other health problems in offspring. It also decreases genetic diversity which weakens the immune system making them more susceptible to disease. Additionally, long-term inbreeding has been linked to decreased fertility and fertility issues for both males and females. If you do decide to breed rabbits, it's important that they come from different lines so as to reduce the risk of genetic disorders or health problems passed on through their genes.