Remdesivir is an antiviral medication administered by an intravenous (IV) method that works against the COVID-19 virus by directly stopping the viral replication process. It interferes with one of the key enzymes the virus needs to replicate and stops the infection from progressing. Remdesivir was one of the original treatments for COVID-19 when it was approved for use by the FDA in 2020. At the time, it was only for use in patients who were hospitalized with the virus. In January 2022, in response to the surge of the omicron variant, the FDA expanded remdesivir’s use for outpatients with mild-to-moderate COVID-19.