u003cstrongu003eYes. If you're not careful, a 12v fridge will quickly drain your car battery.u003c/strongu003e You should never run a 12v fridge off your car battery when your car isn't running. For long-term power for your 12v fridge, consider using a portable power bank like a Yeti Goal Zero or Jackery power station. If in a campervan, consider a solar power setup.