Yes, they can, albeit subject to doctor approval. You should note that ingredients, such as Buchu leaf and vitamin C, have been known to support UTIs by fighting bacteria, reducing pelvic inflammation, and minimizing urinary burn or itchiness with antibiotics working systemically. In case of being diagnosed with severe kidney infections, this may necessitate a physician-guided treatment. Note that Fluxactive Complete is an additive support formula rather than a primary UTI remedy.