You should be able to change your H1B job profile if the AI job is the same or similar to the existing H1B job. Same or similar is a general rule which means that if your new job profile is about 50% same, you should face no issue. Example: A Java software developer on an H1B visa should be able to easily change to an AI (artificial intelligence) job and get an H1B extension, amendment, or transfer approved. At this time, there is no such policy available.