People are rarely difficult and toxic for absolutely no reason. It's possible that your coworkers are being difficult because they're dealing with personal issues. It's also possible that you're doing something to frustrate others without even knowing it. In either case, it's best to talk to the coworkers you're coming into conflict with privately. Approach each conversation with empathy and compassion. If it's something you're doing, you can correct the behavior. If it doesn't have anything to do with you, you can stop taking it personally. Either way, you need to talk to your coworkers.