Vo filme Godzilla hrajú Matthew Broderick (Dr. Niko Tatopoulos), Jean Reno (Philippe Roaché), Maria Pitillo (Audrey Timmonds), Hank Azaria (Victor 'Animal' Palotti), Kevin Dunn (Colonel Hicks), Michael Lerner (Mayor Ebert), Harry Shearer (Charles Caiman), Arabella Field (Lucy Palotti), Vicki Lewis (Dr. Elsie Chapman), Doug Savant (Sergeant O'Neal), Malcolm Danare (Dr. Mendel Craven), Lorry Goldman (Gene, Mayor's Aide), Christian Aubert (Jean-Luc), Philippe Bergeron (Jean-Claude), Frank Bruynbroek (Jean-Pierre), François Giroday (Jean-Philippe), Nicholas J. Giangiulio (Ed), Robert Lesser (Murray), Ralph Manza (Old Fisherman), Greg Callahan (the Governor), Chris Ellis (General Anderson), Nancy Cartwright (Caiman's Secretary), Richard Gant (Admiral Phelps), Jack Moore (Leonard), Steve Giannelli (Jules), Brian Farabaugh (Arthur), Stephen Xavier Lee (Lt. Anderson), Bodhi Elfman (Freddie), Rich Grosso (Jimmy), Lloyd Kino (Japanese Tanker Cook), Toshi Toda (Japanese Tanker Captain), Clyde Kusatsu (Japanese Tanker Skipper), 加藤雅也 (Japanese Tanker Crew Member), Glenn Morshower (Kyle Terrington), Lola Pashalinski (Pharmacist), Rob Fukuzaki (WIDF Co-Anchor), Dale Harimoto (WKXI Anchor), Gary W. Cruz (WFKK Anchor), Derek Webster (Utah Captain), Stuart Fratkin (Utah Ensign), Frank Cilberg (Utah Sailor), Jason Edward Jones (Utah Sailor), Roger McIntyre (Utah Sailor), David Pressman (Anchorage Captain), Robert Faltisco (Anchorage Ensign), Christopher Darius Maleki (Anchorage Ensign), Scott Lusby (Anchorage Ensign), Ali Afshar (Anchorage Sailor), Terence Paul Winter (Apache Pilot), Kirk Geiger (Apache Pilot), Pat Mastroianni (Apache Pilot), Eric Saiet (Apache Pilot), Burt Bulos (Apache Pilot), Robert Floyd (Apache Pilot), Seth Peterson (Apache Pilot), Jamison Yang (F-18 Pilot), Nathan Anderson (F-18 Pilot), Mark Munafo (F-18 Pilot), Dwight Schmidt (F-18 Pilot), Dwayne Swingler (Raven Pilot #2), Lawton Paseka (Officier), Greg Collins (Soldier on the Bridge), James Black (Soldier), Thomas Giuseppe Giantonelli (Soldier), Paul Ware (Soldier), Montae Russell (Soldier on Plane), Christopher Carruthers (Radio Technician), Daniel Pearce (Radio Technician), Mark Fite (Radio Operator), Craig 'Radioman' Castaldo (Radio Man), Eric Paskel (Rodgers), Lee Weaver (Homeless Guy), Leonard Termo (Homeless Guy), Joshua Taylor (Spotter), Al Sapienza (Taxi Cab Driver), Stoney Westmoreland (Tunnel Guard), Gary Warner (Gun Technician), Ed Wheeler (New York Cop), Bill Hoag (New Jersey Cop), Joseph Badalucco Jr. (Forklift Driver), Jonathan Dienst (Field Reporter), Benjamin Baird (Reporters), Madeline McFadden (Reporter), Julian M. Phillips (Reporter), Raymond Ramos (Reporter), Gary A. Hecker (Creature Vocals (voice)), Frank Welker (Creature Vocals (voice)), Al Leong (Japanese Fishing Boat Crewman), Ed Godziszewski (Bridge Onlooker (uncredited)), Steven Ho (Japanese Fishing Boat Crewman (uncredited)), George Cheung (Japanese Fishing Boat Crewman (uncredited)), John Koyama (Japanese Fishing Boat Crewman (uncredited)), Al Goto (Japanese Fishing Boat Crewman (uncredited)), Norman Fessler (WIDF News Worker in Elevator (uncredited)).