The shot itself is not typically associated with significant pain, even for patients with low pain tolerance. It is an injectable medication administered subcutaneously (under the skin) using a small needle. Many patients find the injections to be relatively painless or only mildly uncomfortable. Topical numbing cream can be applied to the injection site if requested.
The injection site may have some minor redness or swelling, but this usually subsides quickly.
As with any medication, individual experiences may vary.