The exact product and its intended application will determine how often capsaicin is used. There are several different ways to get capsaicin, including lotions, ointments, and supplements. Follow the directions recommended by the product's manufacturer for topical treatments, such as reducing arthritic or muscular discomfort. Capsaicin topicals may often be used up to three or four times per day, but for more precise instructions, it is preferable to refer to the product label or speak with a healthcare provider.