Multisystem inflammatory syndrome in children (MIS-C) is a condition where different body parts can become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs. We do not yet know what causes MIS-C. However, we know that many children with MIS-C had the virus that causes COVID-19, or had been around someone with COVID-19. MIS-C can be serious, even deadly, but most children who were diagnosed with this condition have gotten better with medical care. Contact your child’s doctor, nurse, or clinic right away if your child is showing symptoms of MIS-C: Fever Abdominal pain Vomiting Diarrhea Neck pain Rash Bloodshot eyes Feeling extra tired Be aware that not all children will have all the same symptoms. Seek emergency care right away if your child is showing any of these emergency warning signs of MIS-C or other concerning signs: Trouble breathing Pain or pressure in the chest that does not go away New confusion Inability to wake or stay awake Bluish lips or face Severe abdominal pain Source: U.S. Centers for Disease Control and Prevention, 2020