Yes. We suggest removing the calibrator tubes from the mattress and marking each with your name and the zone number. The zone at the head of the mattress is zone 1 or Z1. The zone at the foot of the mattress is zone 7 or Z7. We do not suggest draining the calibrator tubes as you can place all 7 calibrators in one box which will weigh less than 50 lbs. and can be reasonably carried. The izone bed can be easily carried and moved without the calibrator tubes in the mattress.