Yes, pot roast can be very keto-friendly. A standard serving (about 3 ounces) of chuck roast gives about 23 grams of protein and 17 grams of fat, with virtually zero carbs, making it a great low-carb, high-protein and high-fat choice for a keto diet. However, the final nutritional value can change depending on added ingredients or sides, so bear that in mind when creating your meal.