Do not talk about your personal life or family, at a job interview you are not expected to talk about your personal life choices. You are asked about your qualification and professional experience. So start talking about your professional background.
Try to tell your work story, make it engaging, compelling, clear, and complete. Go back in time to the earliest job you ever had. Tell them what company you worked at, what the title was, how long you stayed in that position, and what your major responsibilities were. Do this for all the positions you had. Try to do mini work snapshots for every position you’ve held up to the current position.
Make these mini-stories achievement-oriented. Add a description of one major achievement in each role. An accomplishment is a situation in which you managed to save time, money, improved processes, improved profitability. It is perfect if this had a quantifiable example.
Once you’ve gone through your entire story, now its time to acknowledge for the employer that you know what the position implies and what you are expected to do in the new role.