Mix-minus is an audio setup technique often used in broadcasting and podcasting. It involves creating a unique audio mix for each output, such as headphones or speakers, where the audio from that specific output is removed from the mix. This prevents feedback loops and echoes. For example, in a podcast, a mix-minus setup would ensure that a caller hears everything from the podcast (the host, other callers, sound effects, etc.) except their own voice. This is crucial as hearing their voice with a slight delay can be very distracting for the caller.