IMODIUM products work by changing the movement of your intestinal wall to help slow the movement of fluid through the gut.3 As a result, there is greater overall absorption and a decrease in a stool volume. While IMODIUM products work to help stop diarrhea, the rate of associated constipation is low. Less than 3% of participants in clinical studies experienced constipation as result of taking IMODIUM products to treat their symptoms.