According to the EU’s drug monitoring organization, a cocaine overdose can happen with roughly 1.2 grams of pure cocaine; however, people who are sensitive to cocaine or who have various genetic components have died from doses far lower – as low as 30 milligrams of cocaine, only 2.5% of the dose considered typically lethal. Regular cocaine users who develop a high tolerance to cocaine have been known to survive up to 5 grams per day.In most cocaine-related fatalities, another drug like an opioid or alcohol is also ingested. The addition of a downer or an opiate with the cocaine makes it very easy to misjudge the amount of cocaine being ingested. Cocaine users in the process of binging (using larger amounts of cocaine and over a longer period than usual) are also at a higher risk of overdose as it is easy to lose track of the amount consumed when dosing many times over an extended period of time.