You can! Just be sure to avoid areas of active eczema inflammation, weeping/oozing eczema. Be sure to only exfoliate once a week using gentle pressure, to remove all the excess dead skin!It's best to rehydrate your skin after your exfoliation to reduce the level of dryness seen in your skin. You can try our CheekGlo Juicy Peach Body Oil as an aftercare to your exfoliation routine.