Absolutely! While cats may use their claws a bit instinctively on the wheel when running (especially when getting the hang of it), they don’t actually need them to stay on it. The foam pads on the inner surface provide them with enough traction to keep their footing, even at high speeds. As for tripods and blind cats, we’ve seen videos of them using the wheel just fine. You may need to adjust your training routine a bit to account for any special needs, and the training period may take a little longer, but they can still use the wheel just like any other cat.