Use of Jardiance may have resulted in amputation, but only in rare and serious cases. A review of several clinical studies found only one case of amputation related to Jardiance. In this case, a person taking Jardiance needed a finger amputation. Amputation was seen in only one person out of more than 1,000 people taking Jardiance.
Two other reports of amputation in people taking Jardiance have been made to the Food and Drug Administration (FDA). These were toe amputations.
Invokana (canagliflozin), a drug that’s similar to Jardiance, has also been linked with amputation. Amputations seen with these drugs typically occurred in people with foot complications from diabetes.
It’s important to note that foot complications are common in people with diabetes. This is because diabetes can cause nerve damage and reduced blood flow to the feet. This can lead to problems in the feet, including:
loss of feeling
lowered ability to fight infections
skin ulcers
dry skin
Proper foot care is very important for preventing serious outcomes, such as amputation. If you’re concerned about the health of your feet, talk with your doctor about ways to take care of them.