The biggest difference is what you use as collateral. With a home equity line of credit, you're using the equity in your home, whereas with a securities-backed line of credit you're using eligible assets in your eligible Fidelity accounts. In addition, a home equity line often comes with specific terms governing borrowing and repayment, whereas the required terms for a securities-backed line of credit are generally less stringent, generally allowing you to access and repay funds on your timeline, as long as you maintain adequate collateral in your account to support your line of credit.