This error is a Windows exception error that occurs when software like HARMONY is trying to access the Windows Registry to read or update a Registration code without the necessary admin rights granted to this software by Windows. The fix is quite simple in most cases.
Right-click on the HARMONY Desktop icon and select “Run as Administrator” or if this option is not visible, using Right Click, select “Properties”, then select “Compatibility” and then select the “Run as Administrator” option.
If this does not work, it might require you to uninstall Harmony, login as Administrator on your computer, re-install it selecting “Everyone can access the software”. But most of the time quick fix works.