Make sure your home is extremely clean and label as many things as possible for your guests so they know where things are and how to use them. Make sure you have all the basic necessities, like plenty of towels, cleaning materials, and extra sheets. Also, set proper guidelines and rules for the rental. Make sure they're easy to understand and have them available for the guests to go over. Make it clear that if the rules are broken, it will cost your guests a fee.