The most important ingredient in Estradot is the synthetic version of the hormone oestrogen, called estradiol hemihydrate. For the patch, it’s released slowly into the body over the course of a few days before it needs to be changed.
Women who have had a hysterectomy can use Estradot safely, women who still have their womb should have an additional progesterone, either from a Mirena ‘coil’ or from progesterone gel or tablets which are taken for several days per month. [popover id=ref2]