Depending on the composition, Adderall’s effects can vary in duration. Extended-release versions of Adderall can last up to 12 hours, whereas immediate-release versions normally last 4 to 6 hours. Remember that even after the effects wear off, the drug may still be found in your system. The precise length of time depends on metabolism, individual variances, and the type of drug test. It is best to share any worries you may have with your healthcare provider, especially if they relate to drug testing or Adderall’s side effects.