We recommend to perform a Clean & Sleep Routine once per week. The heliOS software will automatically remind you when a Clean & Sleep Routine is due. The assay rinses the fluidic system with water to remove residual salt and with 70% ethanol. Afterwards, all tubes are vented with air. The procedure takes approximately 35 minutes and you will need a heliX Maintenance Chip. Keep in mind, that the instrument cannot be used afterwards until a Wake Up & Prime Routine.