Yes, you can. Again, depending on the software you are using, the way you do this can be either automatic or manual. If the process is automatic, you simply need to select which monitors you want to use for capturing. For the manual setup, you might have to define the recording canvas you want to use. For example, if you want to capture two Full HD monitors side by side, the canvas will need to be double that size in width. In this case, the resolution of the single monitor is 1920x1080 pixels. Therefore, the recording size will have to be two times the width of 1920, which is 3840x1080 pixels.