The best ADC to play with Senna in LoL Ezreal – The undisputed no. 1 for Senna. ... Jinx – late-game carry potential. Despite some nerfs in the past season, Jinx is still a great candidate to play alongside Senna. ... Ashe – it's all about the slows. ... Caitlyn – the oppressive bot lane duo. ... Jhin – the Caitlyn alternative. Jul 25, 2024