From the airport terminal, you can reach downtown Santiago in about 45 minutes by car. There are several options to reach downtown Santiago de Chile. The CentroPuerto bus or buses for $1800 per trip, cabs for $20,000 (27 euros) and shared for $7600 (10 euros), or a local agency.  The option of a transfer with a private driver is the most practical and safe.  The shared transfer with a private driver is also possible for the return to the airport from downtown Santiago de Chile. It is also possible to book your airport-hotel transfer in advance but it is, of course, more expensive.