Under most circumstances, no. Once you have tendered your resignation and your employer has accepted it, you are typically unable to rescind the decision. This is because, by resigning, you essentially agree to terminate your employment relationship with the company. There may be some limited circumstances where you can reverse your resignation. For example, if you resign in a moment of intense anger or frustration and later regret your decision, your employer may allow you to take back your resignation. However, this is generally at the employer's discretion and will likely only be allowed if it isn't too late or disruptive for the company.