Six popes are buried in Saint Mary Major: Pope Honorius III (1150-1227), Pope Nicholas IV (1227-1292), Pope St. Pius V (1504-1572), and Pope Sixtus V (1521-1590), Pope Clement VIII (1536-1605), Pope Clement IX (1600-1669).  Also, St. Jerome, a priest of Rome and the translator of the Scriptures into Latin, is buried in the Bethlehem Crypt at Saint Mary Major.