Methadone is a medication that is used to treat pain and addicts. It is a synthetic opioid that is similar to morphine. It binds to the same receptors in the brain as other opioids and produces similar effects. However, it is not as potent as other opioids and has a long half-life, which means it can stay in your system for a long time. Methadone is available in both pill and liquid form. It is usually taken orally, but it can also be injected. The medication can be taken with or without food. However, there are some things you should not take with methadone. Alcohol, sedatives, and other opioids can interact with methadone and increase the risk of side effects. You should also avoid grapefruit and grapefruit juice, as they can increase the levels of methadone in your blood. If you are taking methadone, make sure to talk to your doctor about all of the medications and supplements you are taking.