You can use the Cipzox pill to treat toothache since it contains three medications: diclofenac, paracetamol, and chlorzoxazone. Diclofenac works by decreasing cyclo-oxygenase (COX) activity, a chemical messenger responsible for pain and edema. You should not use this medicine without first consulting with your dentist. Several causes can result in a toothache. Do not attempt to self-medicate.