Flossing plays a key role in removing plaque and food particles from between the teeth and below the gumline and should be part of your daily oral care routine. Rinsing with mouthwash is not a replacement for flossing and brushing, but new research proves that LISTERINE adds clinically proven benefits to any oral hygiene routine. A complete routine of brushing, flossing, and rinsing with LISTERINE mouthwash can provide a clinically proven incremental benefit to brushing and flossing alone. LISTERINE helps reduce plaque build-up above the gumline with continued daily use, and reaches virtually 100% of the mouth, providing immediate germ-kill action in parts of your mouth brushing and flossing alone cannot reach