Epoxy resin can adhere to plexiglass, but there are some factors to consider. One important consideration is the surface energy of the material. Plexiglass has a surface energy close to epoxy resin, allowing for some adhesion. However, it is possible to separate the cured resin from plexiglass with force. Another factor to keep in mind is the thickness of the plexiglass. Thin acrylic may warp due to the heat generated during the resin curing process. It is recommended to ensure that the plexiglass does not have any movement, as flexible acrylic may cause the resin to crack or detach. By taking proper precautions, such as ensuring a strong bond and avoiding movement, epoxy resin can be used to adhere plexiglass.