These two assets are both digital currencies, but there are some key differences between them. BNB is the native token of the Binance cryptocurrency exchange, while BUSD is a stablecoin that is pegged to the US dollar. BNB can be used to pay fees on the Binance exchange, and can also be traded on its own or against other cryptocurrencies. BUSD, on the other hand, is designed to be a stable store of value and can be used to trade on any platform that accepts it.