Yes. The thicker mucus in the lungs of people with CF can trap germs, increasing the likelihood of respiratory infections. These can include:
chronic bacterial infections, such as those with Haemophilus influenzae,Pseudomonas aeruginosa, and Staphylococcus aureus
chronic fungal infections, such as those with Aspergillus species
acute viral infections, such as the common cold, the flu, and respiratory syncytial virus (RSV)