The main clinical manifestation of endometrial hyperplasia is abnormal uterine bleeding, and in approximately 15% of patients with a history of abnormal uterine bleeding, a diagnosis of some form of hyperplasia is made.
In some cases, endometrial hyperplasia may present with fever, severe abdominal pain or abdominal swelling, but may also be asymptomatic. If endometrial thickening occurs in young patients, it may cause infertility due to a non-functioning endometrium.