Italy is a very safe country for solo female travelers. In fact, Italy is where I fell in love with solo travel! For most, pickpockets are the biggest threat in Italy. However, just because a country is safe does not mean that bad things can't happen. Always follow a set of safety protocols when traveling, especially when traveling alone as a woman. Never leave your drink unattended or advertise the fact that you're traveling alone, and always keep your friends/family informed of your plans. If you exercise the proper precautions, you'll be perfectly safe during your trip to Italy.