Your oral sleep device should be washed each day with a toothbrush and toothpaste. This is easily achieved and can be done as part of your usual daily dental hygiene routine. Once each week it is advised that the device is deep cleaned and sanitised. Some people use denture tablets, but you can also use water and white vinegar. Either way, the device should be submerged for about five minutes and scrubbed with a soft-bristled brush before giving it a thorough rinse and drying it.