If you are currently taking a reflux medication like a PPI or H2 blocker, we do recommend tapering off when you begin taking Khelp. Here is the recommended tapering protocol: Take your regular treatment along with Khelp for 2 days Start tapering the OTC medication to every other day for about 4 days (continue taking Khelp daily) Continue to taper OTC medication to every third day the next week Drop to every 4th day the following week If symptoms are controlled, continue with Khelp only We suggest starting with 3 capsules vs. 2 if symptoms are more severe. Gastric acid levels constantly vary, so dosing and treatment can also vary. A smaller or more occasional dose of OTC medications can be combined with Khelp, if needed. Be sure to consult with your doctor before making changes to your treatment plan.