There are several bioavailability-enhancing techniques, including Lipid-Based Drug Delivery Systems (LBDDSs), chemical modifications, crystal modifications, and inclusion complexes. However, non-LBDDS techniques have multiple potential downsides, including that they have complex processes, are cost and energy-intensive, result in low stability, and produce limited dosage forms (1). On the other hand, Micellae’s LBDDS technology, O2W, has a simple and inexpensive production process, is highly stable, and can be used to produce an unmatched variety of dosage forms. O2W was engineered to significantly enhance the solubility, bioavailability, and time of onset of fat-soluble compounds, including cannabinoids. Free of PEGs and medium/short-chain alcohols, O2W is the only self-dispersing and fully water-dilutable Self-Microemulsifying Drug Delivery System (SMEDDS) made with food-grade excipients. Nouraei, M. An Introduction to Micellar Solubilization Technology. 1–11 (2020).