GERD has been known to significantly negatively impact an individual's quality of life and ability to work and even disrupt their everyday activities.  An article in the National Library of Medicine mentions that Gastroesophageal Reflux Disease (GERD) affects a person's health, social and daily functioning, and emotional and physical activities. It is also known to interfere with a person's sleep cycle and work.  The cross-sectional study involved 258 patients who were diagnosed with GERD. Among these, 112 had chest pain issues. Researchers used a Hospital anxiety/ depression scale for assessing symptoms of depression and anxiety in these patients.  This study showed that 107 patients faced depression, 89 dealt with anxiety, and 70 had depression and anxiety. The authors hence concluded that cases of depression and anxiety were seen in preponderant GERD patients, particularly those who had chest pain concerns.