No. The time it takes for the information to reach its destination depends on which data center location (US or EU) you choose and from which location you transfer the data to the backup server for the backup. Nevertheless, there's no need to worry about any noticeable latency (delays in the signal run times) to your IT infrastructure during data transmission, intermediate storage or data packet testing. It will, of course, take a little longer if you're located in the US and create a 100-gigabyte backup in a European data center instead of US data center. Still, your IT infrastructure will continue to work latency-free.