Certain types of liver disease can increase your risk of developing The cancer of the liver., also known as hepatocellular carcinoma (HCC). Because of that, doctors recommend regular screening for HCC in people with the following liver conditions: cirrhosis, hepatitis B, hepatitis C, and hepatitis D. The 2018 American Association for the Study of Liver Diseases (AASLD) HCC guidelines recommend ultrasound screening for HCC every 6 months in most adults with cirrhosis.