Deceiving the polygraph, misleading, outsmarting, or confusing it is impossible. The same applies to laptops and monitors, as they represent technology that executes clearly defined algorithms. The polygraph is a complex and highly sensitive device. Modern polygraphs record up to nine reflexively changing psychophysiological parameters, ensuring high accuracy of results. Errors in lie detection are not instrument errors but errors of the polygraph examiner. Insufficient qualification can lead to inaccurate results. An experienced specialist cannot be deceived by medicinal blockers, ‘home remedies,’ or even specially trained individuals. We are familiar with all the methods and means described on the internet and other sources for combating the polygraph: self-inflicted pain, sleep deprivation, ten cups of coffee/tea, sedatives, abstraction from reality, meditation. There are corresponding detection methods for each of these techniques. If the polygraph examiner detects an attempt at resistance, it is clearly stated in the conclusion, and the client of the investigation makes appropriate decisions regarding the person who resisted. Please, do not resist, do not complicate your life. An attempt at resistance will be detected, and you will have to seek justifications.