Generally, users have reported they got their desired results generally within 1 week of use and some reported they got results after 2-3 weeks. Every individual is unique and has a different reaction to the different supplements. However, it is recommended by Dr Gundry and Gundry Md to consult your physician before taking any supplement. Keep the consistency for better results and take the Bio Complete 3 as it has been prescribed by Gundry Md.