The best medical weight loss option is the use of semaglutide, a prescription medication that works by increasing levels of serotonin and other hormones in the body. Semaglutide helps to reduce appetite and cravings. It also helps to boost metabolism, which can make it easier to lose weight. Other medical weight loss options include dieting, exercise, lifestyle modifications, and other medications that may have impacts in other areas of your health or can’t be used for prolonged periods.