Adult male Maine Coon cats typically weigh between 15 and 25 pounds, while adult females usually range from 10 to 15 pounds. This breed is known for its large size, often regarded as one of the largest domestic cat breeds. The substantial weight range reflects their muscular build and long body structure. Owners should monitor their Maine Coon's diet and exercise to maintain a healthy weight, as their large size can predispose them to obesity, which can exacerbate potential health issues like joint problems.