With the use of rapid molecular diagnostic tests as the initial diagnostic test in all persons with signs of TB. -> they have high diagnostic accuracy and will lead to major improvements in the early detection of TB and drug-resistant TB. Example rapid tests: Xpert MTB/RIF, Xpert Ultra and Truenat assays. Diagnosing multidrug-resistant and other resistant forms of TB can be complex and expensive. It is hard to diagnose TB in children.