We find that placing on a very cold coolpack works really well. The colder the better, ideally having been in a freezer.nSqueeze the Blood Temp Indicators and then place on the coolpack , leaving the adhesive liner on the Blood Temp Indicator.nThe activated product can stay on the coolpack for a very long time. We recommended to have this prep area close to the blood-bag fridge and near to the time of use.nThen, when the blood bag or blood bags have been prepared for the Blood Temp indicator, simply remove its adhesive liner and adhere to the blood-bag.nnExtra tip: Blood bags can warm up surprisingly quickly when placed on an counter in a room temperature environment. To keep them cool longer, while preparing them, lay them on a coolpack as well.