It really depends on the trader's experience and the market conditions. In case you are just getting started with margin trading, it is better to use isolated mode with small leverage so you don't end up losing all the funds you have in your margin account while learning the basics of margin trading.  On the other hand, seasoned traders should use cross margin mode because it reduces the risk of getting liquidated, especially during extreme market volatility.  Cross mode is geared towards traders who are confident in their trading strategy and technical analysis skills because it comes with a huge risk.