Anal itching or pruritis ani can be caused due to various reasons a few of which are infections, ongoing diarrhea, dermatitis (skin inflammation), and hemorrhoids. Pruritis ani can also be caused as a result of infestation with Enterobius vermicularis, or pinworms, particularly in children. These worms arise from the anal canal, especially at night and in the morning, thereby worsening pruritis at those times. However, these worms are rarely the cause of anal itching in adults. If these pinworms are identified in children, they can be treated with Albendazole or Mebendazole.