We’ve come a long way from the old treatment option of swallowing handfuls of pills all day every day. In many cases, treatment now means taking one pill a day, making HIV more easily managed than even diabetes or heart disease. There are also prevention medications available for those who may be at high risk. In addition, the Covid-19 vaccine development led to advances in messenger RNA (mRNA) technology that we hope might be the key to unlocking an HIV vaccine in the future.