As with any heavy-duty product, staple guns are as safe as the user makes them be. Looking out for your health can be as simple as putting on gloves or goggles, and not doing these things can leave you with an unexpected trip to urgent care.
As a general rule of thumb, staple guns can be dangerous as there is a high risk of skin puncture if used carelessly. This scenario can affect you even if you’re wearing thick gloves due to the force the staple gun exerts.