Elevation of the ASO titre in isolation without any features of acute rheumatic fever does not warrant 5-year treatment with penidure. This means that as long the child does not have migratory joint swellings, cardiac involvement (normal ECHO), rash, abnormal movements or nodules under the skin the ASOT is simply a reflection of a recent Streptoccocal infection and needs only one penidure for clearance.
2. Elevation of uric acid in children is often a reflection of increased body mass and usually does not suggest gout. It needs only regular exercise and optimal weight, no drugs.