As a freelancer, the IRS allows you to deduct several business expenses from taxes. These expenses include a variety of expenses that are common for businesses. It includes home office or home office costs, home office deductions, rental supplies, office supplies, education expenses, travel costs, supplies, the personal vehicle used for business travel, health insurance, retirement and membership costs, business expense, etc. The only thing to keep in mind is to deduct only the amount that is actually business-related expenses.