It is possible to start a Ford F-150 truck without the key or hotwiring it, but it requires a special tool called a "passive anti-theft system" (PATS) key[1]. This key can be used to bypass the ignition and start the engine. However, hotwiring is not recommended as it can damage the vehicle and is illegal in many places[2][3][4]. It's important to keep your keys safe and secure to prevent theft[5].