Using a standing desk offers several benefits, including improved posture, increased calorie expenditure, and reduced risk of sedentary-related health issues. To set up a standing desk correctly, adjust the height so your elbows are at a 90-degree angle when typing, with your screen at eye level. Use an anti-fatigue mat for cushioning, wear supportive footwear, and alternate between standing and sitting throughout the day to avoid prolonged static positions.