The primary difference between micro-segmentation and macro segmentation lies in the level of granularity. Micro-segmentation involves dividing the market into very small, detailed groups based on specific behaviors and preferences, enabling highly personalized experiences. In contrast, macro segmentation groups customers into larger, broader categories with shared characteristics. Micro-segmentation focuses on customer behavior and lifecycle stage groups, while macro segmentation uses general demographic and geographic data. This differentiation allows businesses to optimize their marketing actions more effectively at the micro level.