An experienced medical professional should be aware of certain ‘danger zones’ associated with Botox complications. Capable injectors know precisely where to administer Botox — and, more importantly, where not to inject. For example: Injecting the frontalis muscles (the two main forehead muscles situated above the eyebrows) instead of the corrugator supercilii muscle (the smaller muscles around the eyebrows) can lead to ‘Spock brows’ — comically arched eyebrows. Injecting the wrong area of the orbicularis oculi muscle, a key upper eyelid muscle targeted in treating crow’s feet, can have adverse effects. Over-diluting Botox injections in the lower facial muscles can result in downturned mouth corners and temporary facial asymmetries. Injecting the risorius muscles instead of the nearby masseter muscle, which is responsive to Botox treatment in patients with bruxism and mandibular hypertrophy, can result in ineffective treatment.