As responsible homeowners, we all want to make sure that our septic systems are functioning properly. One of the concerns that many people have is whether or not they can use toilet cleaner with a septic tank. You should avoid using cleaners that contain bleach or other harsh chemicals. These can harm the septic system and kill the beneficial bacteria that are necessary for proper functioning. Instead, look for cleaners that are labeled as septic-safe or use natural cleaners like vinegar or baking soda. Bleach does not dissolve toilet paper. This is because toilet paper is made from cellulose, a plant-based material that breaks down best when exposed to extremely acidic compounds. Bleach is a highly alkaline cleaning product.