Since he is good at sustained damage with hit scan capabilities, slow-moving characters are typically more accessible for him to track down. With Pharah, for example, she has lead time while being a flying character, and when she is in the air, she is relatively slow. Another tip would always be to try and aim for the opposing team’s tank’s shield if possible. Since Soldier 76 has so much constant and sustained damage, he can destroy a character like Reinhardt’s shield faster than other DPS characters.