Taking your vitamins with a glass of water is recommended over consuming them with a cup of coffee. Coffee acts as a stimulant, accelerating the movement of substances through your digestive tract, which may hinder the complete absorption of nutrients from your vitamins. Moreover, coffee can lead to increased urination, causing water-soluble vitamins to be eliminated from your system more rapidly. To optimize nutrient absorption, it's advisable to finish your coffee at least 15-20 minutes before taking your vitamins. Alternatively, consider taking your vitamins a few hours after finishing your coffee to ensure that the absorption process is not compromised. This way, you can make the most of the nutrients in your vitamins and support your overall health effectively.