Pudendal neuralgia is chronic pelvic pain originating from damage to or irritation of the pudendal nerve. The pudendal nerve is the main nerve of the pelvis made up of sensory, motor, and autonomic fibers that runs through the lower buttocks, perineum (area between the buttocks and genitals), area around the anus and the rectum, vulva, labia, clitoris, and scrotum.