Radiesse is a dermal filler made with calcium hydroxyapatite gel microspheres to correct lines and wrinkles in the face. It’s a little bit longer-lasting than Restylane. It’s firmer, which can make it better for areas that need more sculpting and support. Unlike Restylane, Radiesse cannot be reversed, however. It also cannot be used in the lips. If you aren’t sure whether Radiesse or Restylane might be better for you, talk with our provider during your consultation.