The health of you and your baby are your priorities. While the Harmony Test provides accurate information about some chromosome conditions, it cannot detect others. For example, this non-invasive prenatal test cannot provide information on some rare chromosomal abnormalities. If your 11-13-week scan shows a high nuchal translucency (3.5 mm or more) or significant defects (such as exomphalos, holoprosencephaly, heart abnormalities, or megacysis), the likelihood of rare chromosomal conditions may be elevated. If this is your experience, you may wish to undergo invasive testing using chorionic villus sampling (CVS) or amniocentesis (amnio). However, these procedures carry a risk of miscarriage. 0.5% chance with single and 1% with twins. In addition, the Harmony Test doesn’t offer information on physical defects. This includes heart and brain conditions and spina bifida. It doesn’t provide details on foetal growth, either. Therefore, we highly advise undergoing safe and non-invasive ultrasound scans at the 11-13- and 20-22-week milestones to check foetal anatomy and well-being. An additional growth scan at 30-32 weeks can examine foetal growth. If you have any questions about your baby’s health and the tests you might need, please do not hesitate to reach out. We’d be more than happy to discuss your concerns.