Your doctor may advise you to take this medication with or without food once daily. To avoid having to get up to urinate after taking this medication, take it at least 4 hours before bedtime. Talk to your doctor if you find you urinate more frequently at night.
It is recommended to take irbesartan/hydrochlorothiazide at least 4 hours before or at least 4 to 6 hours after certain drugs for lowering cholesterol (bile acid-binding resins such as colestipol and cholestyramine).
Treatment response and medical condition determine the dosage. Your doctor should monitor your renal function if you have a history of kidney problems. Do not take extra doses as it will not hasten treatment and has an increased risk of experiencing side effects and adverse reactions.
To maximize its effectiveness, take this medication regularly. Remember to take your medicine at the same time every day. It is still important to take this medication even if you feel well. Most people with high blood pressure do not experience symptoms.