As a matter of fact, no. When you place the Ante Bet and go to the paytable to see how much the max win is, you will see that you could get 4,167x the stake with it active. This means that the max payout of 5,000x the stake is still calculated according to the max wager of 125 credits, so the absolute max win in the slot is 625,000 credits, and that’s it.