Botulinum toxin was discovered in 1946. Its use in medicine started in 1970 in ophthalmology to treat strabismus, blepharospasm and hemifacial spasm. The aesthetic benefit of botulinum toxin was observed accidentally in the late 80s.
Some research in ophthalmology showed that patients treated with Botox for blepharospasm practically had no expression lines between the eyebrows, commonly known as glabellar or frown lines.
Botox has been used in aesthetic medicine for over 25 years. Numerous studies have demonstrated that it is safe to use, and we therefore have authentic scientific knowledge about this product (as well as many studies carried out on its safety).