You should follow your physician’s directions, says Dr. Palm, but most scar creams can and should be used shortly after your sutures are removed. However, you may need to use a treatment for several months to see the best results. Dr. Brazzo, who has developed his own post-surgical scar gel, says his patients typically start the treatment regimen immediately after surgery and use it four times a day for one week after surgery, then decrease it to just bedtime for one or two months.