The optimum threshold for predicting severe OHSS was 19 follicles, which was also the optimal threshold for predicting moderate to severe OHSS. A threshold of 12 or more follicles should be used to avoid inducing multiple births for patients who may not want more children. Hyperstimulation results in increased production of hormones that cause fluid buildup in the body and make the ovaries larger. It can lead to premature rupture of the eggs if the patient does not receive adequate treatment. Women who have hyperstimulated themselves are at risk of developing ovarian cancer later in life. Men are also at risk of developing prostate cancer. OHSS can be mild or severe. Mild cases include shortness of breath, headache, nausea/vomiting, abdominal pain, diarrhea, and leg swelling. Severe cases involve all of these symptoms plus weight gain, blurred vision, chest pain, and low blood pressure. Women with mild OHSS can go back to their normal lives after receiving supportive care. They will need to be monitored by a doctor during their recovery period. Women with severe OHSS require hospitalization and intensive monitoring. Their conditions must be assessed regularly by doctors to ensure that they do not develop complications from the disease.