Rocky Mountain spotted fever (RMSF) is a bacterial infection characterized by fever, headache, and rash. It can be deadly if not treated early and accurately. The rash often develops on the soles of the feet and hands two to four days after the onset of fever and later spreads to other areas of the body. The rash may appear as pinpoint spots or larger red splotches. After recovery, patients could be left with paralysis, mental disability, hearing loss, or permanent damage to the blood vessels, leading to amputation of fingers, toes, arms, or legs.