Transgenics can be dangerous to the entire biosphere since the transfer of genes between species may have immediate and long term unpredictable consequences. The creation of new species by nature is a slow process, dependent on causal mutations and natural selection, a relatively safe process for the ecological equilibrium. It is impossible to know how the fast and artificial introduction of transgenic beings in nature affects ecosystems.
Pathogenic agents may be involuntarily created in laboratories, spreading unknown diseases; transgenic species may uncontrollably proliferate destroying ecological interactions that have taken thousands of years to be established; the ingestion of transgenic food also has unpredictable effects.