Bone cancer surgery is an invasive surgery and, therefore, comes with the risks generally associated with such a procedure. This includes: infection, excessive blood loss, pain, and numbness and/or stiffness. As with most cancers, there is also the risk that the cancerous tissue may persist after surgery which is why it is advised that the patient receive regular check-ups. With surgeries that affect limbs, there may be a permanent change to how the limb performs in the future.