Taking Delta 9 THC on an empty stomach may lead to a quicker onset and potentially stronger effects, especially with edible products. This is because there is less food to slow down the absorption of the cannabinoid THC into your bloodstream. However, some may find this leads to an uncomfortable intensity of effects or stomach discomfort. So, it is often recommended to consume Delta 9 THC products and some food, especially if you're new to them or sensitive to their effects.