Most changes will not affect your H-1B status as long as you continue to work on H1B for the employer. You may change H-1B employers without affecting status for which your new H-1B employer must file a new I-129 (Petition for Non-immigrant Worker), before you start working for him. Any merger/sale of your H-1B employer’s business should not affect your status However, due to the change if you are working in a capacity other than the specialty occupation for which your employer petitioned, it is a violation.