Thank you for your quiry.. First of all in my opinion you should not stop and start any medicine haphazzardly without asking a doctor.And the medicines you are taking need strict precautions. As Eliquis is an anticoagulant and premature discontinuation can cause thrombotic events (haematomma in spine,brain or other organs of body,nose bleeds,eye bleeds etc),which can be life threatining emmergency. For your symptoms of energyless and lifeless the cause can be side effects of sotalol..My suggestion would be you visit your doctor and discuss ,as sotalol can be changed to other anti fibrillation drugs for treatment. Surely my answer will be helpfull for you,you can ask further.. Regards , Dr.Maheshwari