The safe temperature for pork tenderloin is anywhere between 145-160 degrees F. Pork tenderloin can be slightly pink inside, but should not be dark pink or bloody. This article is a great guide for different temperatures. We use this instant read thermometer (affiliate) to test it periodically as it bakes. We prefer to remove ours at 145° knowing that it will continue to cook slightly as it rests. This way it stays moist and tender!