Like most other cannabinoids, THCV is considered non-toxic and generally safe to use.
Based on the still limited animal studies with THCV, it’s reported to show no signs of toxicity. Unfortunately, however, there isn’t extensive research available.
Also, mind that THCV use can interfere with other medications. Similar to other cannabinoids, THCV may affect blood pressure, intraocular pressure (eye pressure), and heart rate.
It's not recommended for people in poor physical health, nursing or pregnant women, and anyone who is under the legal age for use.
As there aren't enough scientific studies on THCV yet, users should always consult with a licensed physician who is knowledgeable about cannabis.