Out of all the casino games featured in our comprehensive guide, keno has the worst (highest) house edge, and it’s in the 20% to 40% range. It’s followed by craps (5.56%-16.67%) slots (4%-6% on average), Caribbean Stud (5.2%), Let It Ride (3.51%), pai gow (2.84%), roulette (2.70%-5.26%; 1.35% on even-money bets), three card poker (2.01% on the play bets), blackjack (0.5%) and baccarat (1.06% on the banker bets). The absolute winner is video poker, which has a negative house edge of -0.76% in the full pay version of Deuces Wild if you use optimum strategy.