SAMe is a naturally produce a substance with a great number of benefits on many body processes and functions, including the liver, the nervous system, mood, and joints. Research reveals potential benefits against a range of mood disorders and anxiety symptoms. Still, SAMe is not recognized as a potential treatment for these ailments. There are potential side effects associated to SAMe, and consumer reviews referencing the formula are mixed. To conclude, we would say that the formula will work for some people, while for others it may show modest results. This is why we advise that you consult a healthcare specialist before deciding on the right treatment for your condition.