This is is a hard question to give one answer to because the time varies depending on cooking method, whether the turkey breast is boneless or bone-in, whether it's frozen or thawed, and how large the turkey breast is. In this Instant Pot recipe, a frozen 2 to 3 pound boneless turkey breast will be cooked in approximately 65 minutes, plus time to come to pressure, an additional 15 to 20 minutes. A thawed turkey breast of the same size will be cooked in 25 minutes. Use an instant read thermometer to check the internal temperature of the turkey. It should be 165°F.