Peplau’s Therapeutic Communication Model is instrumental in addressing and reducing anxiety and depression in patients both before and after CABG surgery. The study conducted by Zarea et al. (2018) sheds light on this aspect by specifically examining how the model can be applied to alleviate the anxiety levels experienced by patients leading up to their coronary artery bypass graft (CABG) procedure. By utilizing evidence-based practices and tools such as the Hospital Anxiety and Depression Scale, the study demonstrated the significant impact of incorporating a coronary specialist in patients’ care. It was noted that patients who had direct engagement with a coronary specialist experienced a substantial reduction in anxiety and depression not only in the preoperative phase but also during their postoperative period and hospitalization. This indicates that the implementation of Peplau’s Therapeutic Communication Model plays a pivotal role in enhancing patient outcomes by effectively addressing and mitigating anxiety and depression throughout the entire CABG process.