Effective treatment, including surgery and chemotherapy, can be administered during certain times of pregnancy. Treatment will be decided based on the stage of fetal development and the stage of cancer. The use of radiation therapy during the first and second trimester of pregnancy is not recommended due to the inability to shield the baby from the radiation. For women in early stages of cancer, treatment usually consists of a mastectomy followed by chemotherapy in the second trimester. Chemotherapy given after the first trimester does not put the fetus at any greater risk, although low birth weight is sometimes a concern. Women at more advanced stages of cancer have much more difficult choices laid before them as to whether they should delay treatment until after birth or start a less aggressive form of chemotherapy, which may not be effective to fight their cancer. It is important for women facing these choices to discuss possible implications with physicians and specialists, as well as to get support from their friends, family and partners.