Yes, the Jeep Grand Cherokee is one of the most fuel-efficient mid-sized SUVs available in the market, over the years, Jeep has optimized the fuel economy of the Jeep Grand Cherokee, overall, the Jeep Grand Cherokee gets 10.3 mpg US city driving and 20.6 mpg-US highway driving despite the evolvement of the Jeep Grand Cherokee engine, that’s gets more powerful features over the years.