No. Although Coinbase is listed as an acceptable financial Institution for download, direct connections are not yet possible.  This is because functionality for cryptocurrency has not been fully implemented on quicken.  According to quicken support, plans are being made for the future implementation of cryptocurrency. But until such plans eventually materialise, there can be no direct connection between quicken and Coinbase.  However, you can download transactions as a QFX file and then upload them to quicken.