I recommend waterproof mattress protectors. I also highly recommend ones that are also dust mite barriers for better health. For a really good terry cloth topped, waterproof mattress protector, for not much money, SafeRest makes one of the highest ratest ones on Amazon! For a 100% waterproof mattress protector that also protects against dust mites and allergens, with a soft top, Ultra Plus makes one of the highest rated ones on Amazon and it's still very affordable! If you are cleaning toddler beds, you can also look into the 100% washable crib mattress from Newton Baby (we have it and love it BTW).