If you're already on Depo and you've decided you want to get pregnant, you're going to have to wait it out. There's no way around it. But 12 weeks after your last injection, you'll be ready to start trying. It may take some time, though. [Sometimes it can take up to 10 months] (https://www.bedsider.org/features/76) after the last shot for fertility to come back completely.