There are no proofs of Clenbuterol affecting the menstrual cycle as such, but it is best to avoid the drug if the blood flow is more than usual. The effects of the drug on voice change might get accelerated during the menstrual cycle. An increase in hoarseness of voice is commonly observed. This will make the female voice more manly. Its effects on the muscles around the vocal cord are responsible for this change. Lengthening of the clitoris is another evident difference observed with the drug during menstruation periods.