Use Asfotase Alfa (Subcutaneous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Asfotase alfa is usually given 3 to 6 times per week. Follow your doctor's dosing instructions very carefully. Asfotase alfa is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions. Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine. You may need to use 2 vials and 2 separate syringes to make up a single dose of this medicine. Follow your doctor's dosing instructions very carefully. Your care provider will show you where on your body to inject asfotase alfa. Use a different place each time you give an injection. Do not inject into the same place two times in a row. Asfotase alfa doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight. You may need frequent eye examinations. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using asfotase alfa. Store this medicine in the original container in a refrigerator, protected from light. Do not freeze or shake this medicine. You may take the medicine out of the refrigerator and let it reach room temperature before injecting your dose. Do not leave the medicine out for longer than 1 hour. Each vial (bottle) is for one use only. Throw it away after one use, even if there is still medicine left inside. Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.