Blebs are blister-like protrusions that occur at the cell surface (reviewed in ). Blebs form, and function, in a series of defined steps. They typically grow to a length of around 2 µm within 30 seconds, before shrinking back for another 120 seconds. Blebs are well known as a by-product of apoptotic and necrotic processes, even though they are not essential for the execution of either of these programs . In recent decades, the role that blebs play in the locomotion of some cell types became increasingly acknowledged. For example, bleb-mediated cell motility was observed in early embryos and was termed amoeboid motility …Read more…