Usually No, there are no side effects of using an air purifier in the home. But there is some air purifier in the market which use some filters for air purification such as Electrostatic Precipitators and Ionizer filters which usually are used to remove some gaseous particles. These filters sometimes *Can* emit small amounts of ozone which is little harmful to any living organisms. So ensure before buying that both filters are not there in the Air Purifiers.