An apicoectomy takes place on the root of the tooth, while a root canal procedure takes place on the tooth (the section above the gum with which we chew). Via the root tip, also called the tooth's apex, the infected tissue is accessed, and a filling is then inserted to seal the end of the root. The appropriate grafting material may come from many sources. It comes from your own body sometimes. However, more frequently, it is an animal or human donor's bone treated by a laboratory to make it sterile and healthy. The grafting material may also be synthetic. It comes in many forms: powder, granules, putty, or even a gel injected with a syringe.