Cells are the building blocks of tissue, and tissues are the basic unit of function in the body. Generally, groups of cells make and secrete their own support structures, called extracellular matrix. This matrix, or scaffold, does more than just support the cells; it also acts as a relay station for various signaling molecules. Thus, cells receive messages from many sources that become available from the local environment. Each signal can start a chain of responses that determine what happens to the cell. Through medical technology we can now understand how individual cells respond to signals, interact with their environment and organize themselves into a healing process. Scaffolds are created utilizing various Regenerative Medicine therapies allowing for the tissue “ self-assemble”.