It is safe to take melatonin supplements every night for the short term. Melatonin, a natural hormone that plays a role in your sleep-wake cycle, is synthesized mainly by the pineal gland located deep within our brain. It releases this important chemical when it senses darkness and suppresses its production during daylight hours as well as early morning sunrises or late evening sunlight exposure; however, if you're taking too much of it on any given day (or even over many days), there's an increased risk of experiencing side effects such as dizziness and drowsiness because these hormones are powerful enough to affect levels not just with getting us out of bed but also with regulating moods so we can stay alert throughout the day despite fatigue lurking beneath.