Botox is licenced in the UK for blepharospasm, hemifacial spasm, cervical dystonia, severe hyperhidrosis of the axillae, dynamic equinus foot deformity due to spasticity in ambulant paediatric cerebral palsy patients, two years of age or older, and for wrist and hand disability due to upper limb spasticity associated with stroke in adults.
In January 2014, Botox was granted a licence for "the temporary improvement in the appearance of moderate to severe lateral canthal lines (crow`s feet lines) seen at maximum smile, either alone or when treated at the same time as glabellar (or frown) lines seen at maximum frown, in adult patients where these facial lines have an important psychological impact".