The average cost for LoadUp’s safe removal service starts at $154. Removal and disposal costs vary depending on the size, weight and location of your safe. For larger, heavier safes, removal service starts at $350. For safes weighing 200+ pounds: In order to provide you with an accurate quote, we require additional information for larger safes. If you have a large safe that weighs more than 200 pounds, please give us a call.