Yes! Allow the mac and cheese to fully cool then you can freeze the entire pan or divide it into individual portions. If you want to reheat directly from frozen, you can cover with foil and bake for 45 minutes at 350 degrees F. (However, leftovers will reheat more evenly if you allow the macaroni and cheese to reach room temperature first.) Another option is to thaw the mac and cheese in the refrigerator overnight and reheat on the grill or in the oven. Just add a little milk to the thawed macaroni, cover with foil and bake for 15-20 mins at 350 degrees F. If you're in a hurry, you can also spoon a serving into a microwavable container, add a little milk, cover with plastic wrap and microwave for 1 minute at a time until warm. (Be sure to stir every minute!)