In preclinical studies (lab and animal models), resveratrol has demonstrated anti-diabetic effects. It is believed to improve insulin sensitivity, reduce oxidative stress, and decrease inflammation, which are all critical components of diabetes management. It has been found to improve glucose homeostasis, decrease insulin resistance, and protect pancreatic β-cells in animal models. Some preliminary human trials also indicate its effectiveness in improving glycemic control in type 2 diabetes patients. In diabetic rats, resveratrol significantly reduced glucose levels and improved cardiac function, reducing ischemic injury and cell death in the heart. A study found that long-term administration of resveratrol improved hyperglycemia and hyperinsulinemia in diet-induced diabetic mice. Resveratrol administration was found to prevent and treat type 1 diabetes in a specific mouse model.