There is no vaccine for anaplasmosis. The most you can do to prevent it is treat your dog with a tick preventative, cut your grass short, and avoid piles of leaves. Check your dog for ticks anytime you have been outside. Taking these measures will prevent most dogs from becoming infected. There is, however, a vaccine for Lyme disease, and most veterinarians recommend it.There is no vaccine for anaplasmosis. The most you can do to prevent it is treat your dog with a tick preventative, cut your grass short, and avoid piles of leaves. Check your dog for ticks anytime you have been outside. Taking these measures will prevent most dogs from becoming infected. There is, however, a vaccine for Lyme disease, and most veterinarians recommend it.