While malaria is present in some parts of Honduras, Roatan is considered to be a low-risk area for the disease. However, it's always a good idea to consult with your doctor or a travel health specialist before your trip to determine whether or not you should take malaria pills before and during your trip. Taking precautions against mosquito bites, such as using DEET-free insect repellent, can help further reduce your risk of contracting malaria during your stay in Roatan. I took malaria pills for my first six weeks in Roatan and thoroughly regretted it. They made me sick for the entire time I was on them, and I only ever met one person on the island who had contracted malaria. However, I am not a doctor and it's best to seek advice from a specialist when deciding to take malaria pills or not in Roatan.