Our favourite adaptation would be encapsulated retinol. It is basically a ‘coated’ type of retinol (at its molecular level). The coating allows for two main actions: For the time-released delivery of retinol into the skin, to avoid side-effects noted above, but without dilution. To travel more deeply into the skin where it can be received more effectively, thanks to its ‘disguise’ (i.e. that outer coating). Of course, if the coating contains other ‘skin goodies,’ then that helps to further benefit dermal function and restoration. These coatings can include moisturizers or antioxidants, like in the case with SkinMedica retinol. Please see more on our website.