Absolutely! The ashes of multiple loved ones can be mixed together to create one setting of a uniform color. Alternatively, multiple sets of ashes can be set "side-by-side" in the same setting, meaning they would be set separately except for where they conjoin. If the ashes are drastically different in color, this can create a striking contrast effect; if they are very similar in color, however, the effect is much more subtle. If you order a piece from our Multi-Setting Collection, each loved one can have their own setting. If the number of settings doesn't match how many loved ones you want to memorialize (for example, if you have two loved ones but want to get a piece with three settings), we can always set your loved ones separately in their own settings and then combine them in the additional setting(s), either by mixing the ashes or setting them side-by-side, as mentioned above.