If you'd like to catch the Megabus from Pittsburgh to New York City, you'll find the pickup location conveniently situated in the heart of downtown Pittsburgh. Make your way to Penn and 10th Street near the David L. Lawrence Convention Center. Remember that the pickup spot may be within a block, depending on whether a conference is happening. Once you board the Megabus, you can expect a comfortable and affordable transportation journey with amenities, including onboard restrooms, individual power outlets, three-point seatbelts, and reclining seats. Remember to book your tickets in advance to secure the best prices for transportation and seat selections, ensuring a smooth transportation trip from Pittsburgh to the bustling city of New York.