Imodium is safe for most dogs with diarrhea if administered at a low dose. However, it's not suitable for diarrhea due to bacterial infection or toxins. When bacteria or toxins enter your dog's body, they need to be removed fast. Diarrhea is the body's method of removing these toxins as fast as possible. However, Imodium would end up inhibiting frequent stools, thereby retaining the bacteria inside your dog's body. In such a case, Imodium would not be safe for dogs. With that said, you can safely use Imodium for dogs in all other types of diarrhea. As a precaution, always consult with your vet before using any medication. Also, keep Imodium away from pregnant and nursing dogs or pooches that suffer from some other disease.