Cyclosporin levels are used by transplant physicians to guide them regarding the doses of cyclosporine usage. Cyclosporin levels may vary depending on the drug dose, intake with food, form of the drug and laboratory standardisation. I do hope you have not changed the chemist from whom you get cyclosporine and that your cyclosporine is genuine. One needs to make sure that the levels are tested the same way, 12 hours after the dose; the time should not be varying; the lab is the same and that it has not changed the method. So there are so many factors, which may explain your drug levels. Which of these is true for you will need an understanding of all of the above mentioned factors.