At no point has AstraZeneca warned patients or prescribing doctors about the drastically increased risk for kidney problems associated with Prilosec. In fact, the drug company has refused to even acknowledge the problem. Because this lack of disclosure put innocent people at risk of a serious medical condition and prevented them from making an informed decision about their health, it has led to numerous lawsuits against AstraZeneca. These lawsuits all claim that this amounted to a defective warning. Failure to warn lawsuits like these are based on a drug maker's legal duty to disclose the potential for side effects related to their drug. Failure to warn medical professionals and patients of the potential for harm associated with their drug can lead to drug companies being held liable for the injuries they have caused. Because studies have shown that there was a connection between chronic kidney disease and proton pump inhibitors since the 1990s, lawsuits against AstraZeneca for the side effects of Prilosec have gained traction in court.