Lewy bodies affect several different brain regions in LBD:
• The cerebral cortex, which controls many functions, including information processing, perception, thought, and language
•The limbic cortex, which plays a major role in emotions and behavior
•The hippocampus, which is essential to forming new memories
•The midbrain, including the substantia nigra, which is involved in movement
•The brain stem, which is important in regulating sleep and maintaining alertness
•Brain regions important in recognizing smells (olfactory pathways)