No. The Federal Sentencing Guidelines are no longer mandatory by decision of the Supreme Court.  They provide a set of factors that a Judge must account for when issuing an appropriate sentence.  Other sentencing considerations not included in the sentencing guideline calculation include how a defendant behaves after his arrest ,if there is mental health or substance abuse issues and whether the defendant commits to treatment and counseling; whether restitution can be paid; what amount of harm was caused to the victim;  whether the defendant suffers from any medical conditions; whether the defendant has family support; whether the defendant is employed ; and whether the defendant has the support of family and friends in the community.
It is critical to work with your attorney so that a judge will be able to see you as the person you are, and not just the offense you committed.