It is common in the early stages of Alzheimer’s for the person with the disease to be aware that something is wrong. They may recognize that they are having difficulty remembering things or getting lost frequently, and may become frustrated or agitated as a result. Many people who are formally diagnosed with Alzheimer’s are cognizant of their diagnosis and may be able to take steps to prepare themselves and their loved ones for their future decline. As the disease progresses, many people with Alzheimer’s often seem to become less aware of their symptoms, though they may still express frustration or seem to feel that something is wrong. They may also become depressed as a result of this continual frustration and ongoing sense of decline.