The study conducted by Pinto et al. (2021) and published in the journal Letters in Applied Microbiology explores the antifungal properties of terpinolene in conjunction with dihydrojasmone against dermatophytes, a type of fungi that cause various skin infections. By investigating the potential synergistic effects of terpinolene and dihydrojasmone with the antifungal drug terbinafine, the researchers aim to enhance the efficacy of antifungal treatment. The study’s findings indicate that terpinolene, in combination with dihydrojasmone, can potentiate the antifungal activity of terbinafine against dermatophytes. Terpinolene has antifungal properties because it exerts antifungal activity by disrupting the integrity of the fungal cell membrane and inducing oxidative stress within the fungal cells. This suggests that terpinolene holds promise as a natural antifungal agent and could potentially be used to augment the effectiveness of existing antifungal treatments. The research contributes to our understanding of terpinolene’s potential in combating fungal infections, offering new insights into alternative and complementary approaches to managing dermatophyte-related conditions.