Because wheatgrass is so unique, your body may have a little trouble digesting it at first. If you are new to wheatgrass juice you might find that you experience nausea, an upset stomach, a headache, or constipation.  The good news is that u003cstrongu003ethese side effects tend to settle down within a week or twou003c/strongu003e as your body becomes accustomed to it.u003cbr/u003eu003cbr/u003eFor that reason, the best option is to start with just an ounce or two at a time. You can follow this up with a glass of water, which should help prevent or reduce any abdominal discomfort. Ideally, try to drink this first thing in the morning, before breakfast. Most people find it works best on an empty stomach, whilst the little energy boost it gives is a great way to start the day!u003cbr/u003eu003cbr/u003eAs your body gets used to wheatgrass, u003cstrongu003eyou can increase the amount you have to 4 ounces at a timeu003c/strongu003e. You could also increase the frequency, adding a shot in the evening too.