Consumption of tomatoes sprayed with Roundup should be avoided. While there might not be immediate visible effects on the tomato fruits sprayed with Roundup, it's important to note that Roundup contains glyphosate, which can be harmful if ingested. The herbicide could potentially leave residues on the surface of the tomato and get absorbed into the fruit as well. To ensure safety and minimize health risks, it is best to consume tomatoes that have not been treated with any pesticides or herbicides.