It completely depends on the level of flow and therefore it differs from one woman to another. If your flow is normal, Rebelle pads can hold the discharge for about 10 to 12 hours very comfortably and if your flow is heavier, you may prefer to change them more frequently. Sanitary pads that are currently available can only be worn for up to 6 hours at a time. But Rebelle pads have zero chemicals or gels and therefore it is safe on your skin and can be used as long as you feel comfortable.