When the oil is all the way up to the 1.0 ML line, there is about 45 individual drops (give or take a drop). This goes for all of our tinctures. For example, a 300mg Tincture has 0.222 mg CBD per individual drop. If I wanted to take 5 mg CBD from it I would take (23 individual drops x 0.222 = 5.1) or half a dropper full (up to the 0.5 ML line).