In addition to different types of Crohn's disease, it's also possible to have different disease patterns. Luminal Crohn's disease describes changes to the intestinal lining due to inflammation the disease causes. Fibrostenosing Crohn's involves strictures, or narrowing of the intestine, that can lead to a bowel blockage. Penetrating Crohn's causes fistulae between the inflamed intestine and other body parts.