The use of food supplements is safe, provided their instructions for use are properly followed. In addition, their contraindications should not coincide with the possible medical history of the user. In the event of a specific health problem, during pregnancy or breast-feeding, for special population groups, such as children or the elderly, or if you are receiving treatment, your physician should be informed. All food supplements by ESI & of Science Of Nature, have been notified to the National Organization for Medicines and include all necessary indications and directions for use on their packaging.