We have naloxone, as we know it today, through the radical activism of people who use drugs, advocates, and allies redistributing the medication to keep each other alive. Naloxone was first patented to treat opioid-related constipation in 1961; by 1995, people who use drugs began distributing naloxone in grassroots networks to keep each other safe. In 2003, the Drug Overdose Prevention Education (D.O.P.E.) Project in San Francisco initiated the first low-barrier community naloxone distribution model. Our naloxone distribution is based on this model.