Capillary electrophoresis is generally used for the separation of ionic biomolecules or chemical compounds. However, with the increasing use of these systems in research and diagnostic fields, a number of technological advancements have helped introduce various types of capillary electrophoresis. These systems range from zone electrophoresis and isoelectric focusing to capillary electochromatography and nano capillary electrophoresis. The most recent advancements gaining importance in the market is CE coupled with mass spectrometry offering great promise for top-down proteomics studies. It is mainly being used for the identification of biomarker peptides in clinical proteomics. Also, this technique is being used for biomarker discovery in kidney disease, prognosis, therapy evaluation, and implications for disease diagnosis. Players are trying to integrate these systems with other analytical instruments for accurate and efficient analysis of protein and nucleic acid molecules.
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