If we go by the nominees at The Game Awards 2021, then the only indie included in the 'Best Music and Score' category was The Artful Escape. So I suppose it would have to be that one. Just for those wondering, the other nominees were Nier: Replicant, Marvel's Guardians of the Galaxy, Deathloop, and Cyberpunk 2077, and Nier: Replicant took home the award.