If your goal is to disable a device long-term, the best way is to remove the batteries. By taking out the batteries, you effectively disable the device until someone puts new ones in. This works for most devices, including laptops, cell phones, and tablets. If you're looking to disable a more industrial piece of equipment, however, simply removing the batteries may not be enough. In this case, it's best to consult with the manufacturer on how best to disable the device.