Thank you, Paulo, and thank you to all of our guests who are attending today. Just a quick note on connectivity as we all may be challenged with broadband issues, if we disconnect for any reason, stay tuned; we'll reconnect quickly. If you lose connection, please log back on. Today's program will cover a range of subjects related to flexible isolators and the single-use concept. I will begin with materials of construction and some of the design and manufacturing techniques that are used. We'll go through a variety of applications in pharmaceutical processing and show real-time solutions that have been installed and proven. David House will join us to go through the benefits of the negative pressure control system and how that influences the performance of flexible containment. Then we'll look at the risk assessment process in actual case studies for performance data, followed by the cost benefits and project management aspects when implementing a flexible isolator project.