Yes. Cells can be harvested from the hydrogel and be used for molecular analyses according to standard procedures. The hydrogel is transparent, and you can use the molecular assay directly with the hydrogel. Additionally, the hydrogel can be easily dissolved by using a homogenizer/ultrasonic processor, so scientists can lysis cells together with hydrogel to extract DNA/RNA.
Please check the protocols for more details: https://www.thewellbio.com/protocols/