The frequency of payouts on 5-reel slots can vary greatly, as it depends on the specific game and its programming. Some 5-reel slots may have a high frequency of payouts, while others may have a lower frequency. The payout percentage and hit frequency are usually stated in the game's rules or information, and can range from 90% to 99%. It is important to note that all slot machine payouts are determined by random number generators and are therefore completely random and unpredictable.