While there is no definitive clinical evidence confirming that smoking weed directly leads to hair loss in humans, indirect links exist that should be considered. Smoking weed can affect the hormonal system, potentially increasing the body’s cortisol levels, also referred to as the “stress hormone.” Chronic stress-related to higher cortisol levels has been identified as an underlying cause of hair loss, as it triggers an abnormal hair growth cycle. Furthermore, marijuana’s impact on mental health may play a role in hair loss.