People with gastroesophageal reflux disease, peptic esophagitis, or an acute hiatus hernia should avoid lemons and lemon juice. This fruit can irritate the lining of the esophagus and cause epigastric burns. Certain antacid drugs should not be taken along with lemon or lemon juice. Antiacids and lemon or lemon juice should be taken three hours apart as a precaution. Although beneficial to one's general health, lemon is extremely acidic, making it difficult for some people to handle. Especially when ingested in big quantities and/or in pure form. As a result, caution is advised in some situations. If you're taking an antacid, use caution. Lemon or lime juice, as well as their liquids, should be avoided when using antacid drugs. Several citrus fruits, in fact, enhance the absorption of aluminum in antacids. It is preferable to take antacids with citrus fruits or juice three hours apart. In the event of GERD and heartburn, moderate intake is recommended. People with gastroesophageal reflux disease, peptic esophagitis, or a hiatus hernia should avoid lemon, lime, and their juices (in the acute phase of these conditions). These foods can irritate the esophageal lining and produce epigastric burns.