This is a great question. It depends on what kind of music you like playing since both have a different tuning. A ukulele is tuned to: ADGCEA A guitalele is tuned to a standard guitar at: EADGBE Also keep in mind, a ukulele has 4 strings and guitalele has 6. So if you want to play some nice Hawaiian classics, go for a ukulele. If you want to play what you hear on the local radio, youtube and most mainstream stuff, then go for the guitalele.