The United States National Toxicology Program and the United Kingdom Health and Safety Executive have concluded that the use of ethyl cyanoacrylate (Instantbond)is safe and that additional study is unnecessary. The compound 2-octyl cyanoacrylate degrades much more slowly due to its longer organic backbone and the adhesive does not reach the threshold of tissue toxicity. To further minimize any risks please use Instantbond in a well-ventilated area.