Sculptra is composed of poly-L-lactic acid, a molecule which is biodegradable, so it does not harm the body and is easily broken down and absorbed. We use a very effective topical numbing agent to numb the skin prior to the injections. The Sculptra powder is also reconstituted with water and lidocaine, so you will feel more numb as the injections are being done. Most people are surprised at how comfortable the treatments are.