Similar to Juvéderm, Restylane fillers are made of a smooth HA gel that’s formulated provide natural-looking benefits. Classic Restylane helps diminish moderate to severe nasolabial folds or enhance the lips. Restylane Lyft is a firm HA gel that is specially formulated to lift the cheeks, enhance the jawline or chin and reduce the appearance of wrinkles. It’s also used to rejuvenate the back of the hands. Restylane Refyne helps smooth moderate smile and laugh lines, Restylane Defyne helps smooth deep smile and laugh lines, and Restylane Kysse is formulated to enhance lip volume and softness. Depending on the type of fillers you need, benefits can last six to 24 months.