According to the National Eczema Society, some of the best choices for eczema-friendly bedding include: 100 percent cotton bedding. Don’t settle for inexpensive cotton weaves that may irritate eczema; look for high-quality sateen or percale bedding. If you’re buying thicker bedding such as duvets and comforters, you may be able to compromise by choosing one with a synthetic fill and a cotton cover for easier washing. Bamboo is more absorbent than cotton and has better temperature regulation. Silk is not only breathable and cool, but it naturally resists dust mites that can irritate eczema. Wool maintains a consistent temperature and resists dust mites. Breathability is an important feature of eczema-friendly bedding because people with the condition often overheat more quickly than the average person. Overheating and sweating can cause itchiness.