You can remove larger marks using the spot healing brush by increasing the size of the brush or simply by clicking and dragging to cover a larger area. However, you’ll generally see more seamless results on smaller areas, like freckles and tiny paint splatters, than you will removing entire objects with the spot healing brush. For very large areas, the regular healing brush is a better option as you can choose exactly which area gets sampled to fill the space where the mark was.