A key distinction between Blazor and React lies in the programming languages they utilize. Blazor harnesses the power of C# and Razor syntax, well-known within the realm of .NET developers. Conversely, React employs JavaScript, the most ubiquitous scripting language on the web. Your preference for Blazor or React may largely depend on your comfort level with either language, as it permits the application of pre-existing skills and toolsets.
The performance dynamics of Blazor and React come with their own sets of pros and cons. Blazor often boasts quicker initial load times when compared to React, although it also presents a larger bundle size, necessitating the inclusion of the .NET runtime and libraries. To mitigate this, Blazor Server can provide swifter rendering times relative to React, given it does not require data transmission to the browser. However, it also manifests a higher latency compared to React, owing to its reliance on a continuous server connection.
React has the potential to outperform Blazor under certain conditions, given its utilization of a virtual DOM that refreshes only the altered segments of the UI. Nonetheless, React comes with its own set of challenges, such as potential memory leaks or unnecessary re-rendering if not optimized correctly.