Despite being used to treat similar digestive problems, probiotics and digestive enzymes are not the same. One major distinction between the two is that enzymes are proteins while probiotics are living microorganisms (good bacteria). That means enzymes can actually digest food and are effective at relieving common issues such as occasional gas, bloating, indigestion and general discomfort. Probiotics, on the other hand, are useful in supporting the overall health of gastrointestinal tract as well as supporting the immune system and other body systems. And probiotics cannot break down the food molecules you eat. Both digestive enzymes and probiotics can be taken together to support digestion and address digestive issues at the same time.