Hello Thanks for the query It looks like you are suffering from Irritable bowel syndrome however I dont think it has anything to do with the Creatinine supplement you have taken 6 years ago. You are on the right treatment for the same and you should continue to take it. I have seen many of my patients do better with meditation and yoga. I recommend the same to you. You could also try alternative medicines like ayurveda and homeopathy as well. However these are some of my suggestions for you 1. Avoid smoking and alcohol 2. Avoid spicy food, fat rich food 3. Drink atleast 8 glasses of water a day 4. Do not go to sleep immediately after dinner 5. Avoid milk, milk products and caffeine I hope I was of help Regards