Starting pitchers play a significant role in determining the outcome of a game and the odds set by sportsbooks. When placing a bet, you should consider the pitchers’ recent performance, their history against the opposing team, and how they fare in the specific ballpark. Some sportsbooks also offer “listed pitcher” bets, meaning your bet is only valid if the specified pitchers start the game. If there’s a last-minute pitching change, your bet will be voided.