Yes, they can. The chemical that pregnancy kits that you use at home contain measures the level of pregnancy hormone. This chemical does not last forever, which is why pregnancy kits have expiration dates. It is essential to check the expiration date before you buy the pregnancy test in the pharmacy or using the one that you had at home. Usually, these kits can still be accurate after two to three years after the manufacturing.
It is also important to remember that these kits should be stored properly. The heat or humidity can damage the test that will lead to false results. Read the instructions before storing and using these kits at home.