In inhalation toxicology, accurately assessing the inhaled dose and particle deposition within the respiratory tract are key challenges. Assumed respiratory parameters may lead to inaccurate estimates of inhaled doses, resulting in erroneous conclusions about the effects on the body. Particle size affects deposition location, impacting the bioavailability and toxicity of the test article. AmplifyBio's inhalation team has extensive experience generating and controlling test atmospheres and interpreting data to address these challenges.