The most common symptoms of lung cancer are: A cough that does not go away or gets worse. Coughing up blood or rust-colored sputum (spit or phlegm) Chest pain that is often worse with deep breathing, coughing, or laughing. Hoarseness. Loss of appetite. Unexplained weight loss. Shortness of breath. Feeling tired or weak. More items... Oct 1, 2019