The first and biggest stock exchange in Canada is the Toronto Stock Exchange (TSX) which opened in 1861 and is located in Toronto, Canada. The Toronto Stock Exchange (TSX) is one of the largest in the world and the third-largest stock exchange in North America, after the New York Stock Exchange (NYSE) and the NASDAQ, which are both found in the US. With over 2,200 companies listed on the Toronto Stock Exchange, Canadians will most likely trade on the TSX. However, with an online brokerage account such as CIBC Investor’s Edge, Desjardins Online Banking, Questrade or TD Direct Investing, investors may also have access to stock exchanges around the world. So in theory and depending on the brokerage firm and platform you use, investors from Canada can trade on the New York Stock Exchange (NYSE), Toronto Stock Exchange (TSX), London Stock Exchange (LSE), Shanghai Stock Exchange (SSE), the Tokyo Stock Exchange (TSE) and more. Good to know Not all brokerage accounts give access to all stock exchanges so it is important to research which stock exchanges a specific brokerage will provide access to before opening an account.