It is safe to use your ultrasonic cleaner on night guards, whitening trays, and toothbrush heads on a daily basis. However, if you choose to use your ultrasonic cleaner on aligner trays, retainers, or products provided by other companies or dentists, we recommend you check with them first before use. It’s impossible for us to know the makeup of all oral appliances put into the ultrasonic cleaner so we cannot be responsible for damages.