Yes, pests can build resistance to treatments over time, especially if the same pesticide is used repeatedly. This is why it's important to use a variety of control methods and not to rely solely on pesticides for pest control. Integrated Pest Management (IPM) approaches, which include a combination of chemical and non-chemical methods, are less likely to result in resistance and are often more effective in the long run. Regularly rotating the types of pesticides used and working with a professional pest control service can also help prevent resistance.