There are several types of alcohol that can be mixed with lemonade, and the best one largely depends on personal preference. Some popular options include: Vodka: This is a neutral spirit that pairs well with the tartness of lemonade and allows the other flavors to shine through. Gin: The botanicals in gin can complement the citrus flavors in lemonade, resulting in a refreshing and complex drink. Tequila: Mixing tequila and lemonade creates a twist on the classic margarita, with the tartness of the lemonade balancing out the sweetness of the tequila. Rum: The sweetness of rum can balance the tartness of lemonade, making for a smooth and easy-to-drink cocktail.