Yes. Research has shown that doing a “split prep” model helps provide a much cleaner colon. The biggest benefit to the split prep is the “bile” that enters into the empty colon can stain it yellow and obscure the doctors views. The “split prep'” which encourages you to take the 2nd half 5 hours pre-procedure eliminates this bile from the colon and provides the best visibility for your doctor. This yields the most optimal exam.