First approved by the FDA in 2000 for cosmetic use, Botox is now approved as a therapeutic treatment option for millions of people suffering from dental-related conditions like jaw pain from TMJ and bruxism (clenching and grinding). Botox, a medical-grade drug produced from the Botulinum toxin, has been proven safe and effective in blocking the nerve impulses that cause muscle clenching, wrinkles, and tension, giving dentists another tool in their kit for helping patients reduce or even eliminate pain.