Medications work differently for different people, but studies show Ozempic is more effective than Saxenda overall. People on Ozempic have a: 86% chance of losing at least 5% weight 71% chance of losing at least 10% weight 56% chance of losing at least 15% weight 39% chance of losing at least 20% weight People on Saxenda have a: 56% chance of losing at least 5% weight 26% chance of losing at least 10% weight 12% chance of losing at least 15% weight 6% chance of losing at least 20% weight