The proper dosage of Harvoni will vary between patients and is based on several factors. You should always follow your doctor’s instructions or the directions on the label. The following information refers to typical doses for adult patients. For patients with genotype 1, 4, 5, or 6 HCV, the recommended dosage is one tablet (90mg ledipasvir, 400mg sofosbuvir) taken orally once per day. In children 3 years and older with hepatitis C virus (HCV) genotype 1, 4, 5 or 6 infection, dosing is weight-based: <17 kg: 1 packet (33.75 mg/150 mg) of pellets orally once a day 17 to <35kg: 1 tablet or packet (45 mg/200 mg) orally once a day ≥35 kg: 1 tablet (90 mg/400 mg) rally once a day or 2 tablets or packets (45 mg/200 mg) orally once a day