The name Santiago originates from the Spanish words Santo, meaning ‘saint,’ and ‘Yago, an old form of the name James. It symbolizes the significance of Saint James, who is considered the patron saint of Spain. On the other hand, Matis is a boys name meaning gift of God and is derived from Matthias, a variation of Matthews. Matthews is an English version of the Greek name Matthaios, which in turn comes from the Hebrew name Mattityahu, which means ‘gift of Yahweh.’