The Schedule C is the form you file for being an independent contractor, having and running your own business, being self employed, etc. Itu2019s used if you receive a 1099 Misc, 1099 K, etc.The Schedule SE is a supplemental form that goes along with the Schedule C. The SE stands for Self Employment (Tax). The form is used to calculate the taxes you owe for Federal Income, Social Security and Medicare. As your independently employed you are responsible for both halves of the Social Security and Medicare taxes.