Yes, certain medications can impact fluid balance. Diuretics (water pills) increase urine output, affecting fluid levels. ACE inhibitors and ARBs, used for hypertension, can dilate blood vessels, altering fluid and electrolyte balance. Nonsteroidal anti-inflammatory drugs (NSAIDs) may cause fluid retention. Corticosteroids can lead to sodium and water retention. Some medications affect renal function, impacting fluid regulation. It's crucial for individuals on such medications, especially those with kidney issues, to be monitored by healthcare providers. Adjustments in medication, fluid intake, and dietary choices might be necessary to maintain proper fluid balance and overall health.