NSAIDs, as the American College of Rheumatology explains, are nonsteroidal anti-inflammatory drugs. They block a hormone-like substance in your body that sends pain messages to your brain. NSAIDs come in many different strengths and can be prescribed by a doctor or purchased over the counter. Prescription-strength NSAIDs, including ibuprofen, are often taken for chronic pain conditions like osteoarthritis, rheumatoid arthritis, and lupus. OTC ibuprofen and other NSAIDs are taken for:
Minor aches and pains (headaches).
Menstrual cramps.
Muscle aches (such as after exercise).
These drugs soothe inflammation, so they’re a good choice if you have a muscle or joint sprain, strain, or swelling. You shouldn’t take NSAID drugs if you:
Have more than three alcoholic drinks per day.
Are allergic to aspirin or other pain medicine.
Take blood-thinners.
Have a bleeding disorder or have had stomach bleeding problems/ulcers.
Have liver, kidney, or heart disease.