Some past studies found an increased risk of ovarian cancer from talcum powder use, but these studies were considered inconclusive because of limitations in the way data were collected and analyzed. Ovarian Cancer Research Alliance provides information based on medical research and best practices. Research regarding a connection between the use of talcum powder and increased ovarian cancer risk is inconclusive. The verdict of recent trials regarding talcum powder will not change the information that Ovarian Cancer Research Alliance provides to women about talcum powder and ovarian cancer. More recent studies on talc and ovarian cancer risk, such as the one published in the Journal of the American Medical Association (JAMA) in 2020, showed that using perineal powder was not associated with a risk of ovarian cancer, compared to never having used it.