Depending on the underlying cause, a toothache may last short or longer. A moderate toothache may occasionally go away in a few days, especially if brought on by momentary sensitivity or minor irritation. However, if the toothache is due to a more significant issue such as tooth decay, infection, or gum disease, it is unlikely to go away without treatment. Toothaches caused by these conditions can persist or worsen over time. In general, seeking dental care promptly when experiencing a toothache is recommended to determine the cause and receive appropriate treatment. Ignoring or delaying treatment can lead to further complications and potentially prolong the duration of the toothache.