CB Radio stands for citizen band radio and is a two-way radio communication system similar to walkie-talkies. Even though CB and walkie-talkies use the same radio waves technology system, CB and walkie-talkies do not communicate since they use separate frequency channels. While CB radios operate on a frequency of 27MegaHertz to communicate, walkie-talkies use a frequency of 30 MegaHertz to 300MegaHertz. CB will only transmit over CB and not over walkie-talkie or any other two-way radio based on the core principle of a radio system that must operate on the same frequency channel for them to talk to each other.