Start by ensuring the Thunderbolt Control Center is installed on your laptop. If the eGPU is not being detected, check if it is showing up in the Thunderbolt/USB4 section in the system report. If the eGPU is not detected, it may be a compatibility issue with the Framework laptop. Check the forums for any known issues and potential solutions. It's also worth checking the BIOS settings to ensure Thunderbolt options are enabled. Make sure you have the latest BIOS version installed.