Yes, although we recommend doing so carefully. Too high of a temperature (above 104℉, or 40℃) may lessen the benefits of the probiotic cultures. If you choose to warm Neocate Syneo Infant, we recommend against using a microwave, as we do for all of our formulas, due to the risk of hot spots and burns. Instead, gently warm cold formula using a bottle warmer, a warm water bath, or by holding the bottle under warm, running water. We suggest using a thermometer to ensure the temperature does not exceed 104℉ (40℃).