We suggest you put the bed frame in a corner leaving 24 to 30 inches from the wall for easy entrance and exit. You can set the head side of the bed to the wall which will save space and also provide support to your headboard (or pillows, if the bed frame is without headboard). This way, you will have larger floor space on one side to accommodate larger items well i.e. study table, etc.  If you place your bed frame in the center, it will look good but the total floor space will split into smaller halves which means you will have a hard time adjusting other items well.