Restylane Refyne and Defyne helps smooth away facial lines and wrinkles and defines and restores volume for immediate, noticeable, yet natural-looking results. While genetics, facial expressions, diet and sun exposure can age one’s facial appearance, it is also caused by changes in facial structure and the gradual loss of facial volume and HA, a natural substance in the body that helps the skin maintain moisture. Over time, we make less HA and this diminishes skin volume and elasticity, making the visible signs of aging more noticeable. The good news is that HA can be restored with Restylane Refyne, a unique innovation of non-permanent dermal fillers that can help improve the shape of your face by gently adding subtle volume and definition to the cheeks, lips, or other facial features to give a more youthful and rejuvenated appearance.