Yes, you can make grilled cheese in the microwave. Just place two slices of bread with cheese in the middle on a plate and microwave for about one minute. You should be able to see the cheese start to melt and turn bubbly. You can also use this method to make other types of grilled cheese sandwiches, such as with ham or tomato slices, or add condiments like butter, mayonnaise, ketchup, or mustard.