The growing problem of antibiotic resistance in nursing homes led to the creation of antibiotic stewardship programs for U.S. nursing homes. An antibiotic stewardship program is designed to optimize antibiotic prescribing and usage in order to reduce the number of antibiotic resistant infections and their associated complications in nursing facilities. These programs are basically antibiotic guides and toolkits made up of 7 core elements to promote optimal patient care and patient safety.