Yes, being aware of your own cognitive decline tends to evoke depression and anxiety. Just the worry that you might be losing your mind can cause you to become depressed or anxious. Plus, neurodegenerative diseases like Alzheimer’s often deplete neurotransmitters, such as dopamine, norepinephrine, and serotonin, which impact one’s mood and calmness. As a result, anxiety and depression occur in more than half of those individuals who get dementia. Meditation, exercise, medication, and therapy emphasizing relaxation are often effective in treating the anxiety and depression that frequently accompany dementia.