If you’re new to retinol, you should start by using the A-Passioni Retinol Cream one to two times per week for a few weeks to allow your skin to adjust (as overuse may cause irritation). From there, you can see if your skin tolerates using it every other day or every day. Be sure not to layer it with an exfoliating product, like the T.L.C. Framboos Glycolic Resurfacing Night Serum, as this will likely lead to irritation.