Yes. Whooping cough, also known as 100-day cough, runs a long course lasting for three to four months. Adequate rest and treatment is essential. With treatments such as antibiotics, it is possible to get symptom relief and prevent the spread of the disease. Yes. Whooping cough, also known as 100-day cough, runs a long course lasting for three to four months. Adequate rest and treatment is essential. With treatments such as antibiotics, it is possible to get symptom relief and prevent the spread of the disease.