The answer is maybe, but not always. It depends on how much you use, how long you leave it in, and how often you do it.   White vinegar can cause damage to your pipes if you use too much of it or if you leave it in your pipes for too long. The acidity of the vinegar can eat away metal and cause corrosion. If you have a small amount of white vinegar left over after cleaning up grease or food spills in your kitchen, pour it down the sink instead of letting it sit there for hours.