Bystolic has known side effects. This is not a complete list and includes frequently reported adverse events. If you experience any signs and symptoms of serious side effects when taking Bystolic, talk to your doctor or emergency care. Report side effects with Bystolic  to your doctor. If you find them unmanageable call your doctor or pharmacist for medical advice about side effects. We also have a pharmacist that can provide counselling when you buy Bystolic online.   chills depression tingling of the hands or feet dry mouth wheezing extreme fatigue cold sweats Absence of or decrease in body movement nausea or vomiting confusion unable to sleep numbness in the hands, feet, or lips Bloating or swelling of the face, arms, hands, lower legs, or feet dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position decreased urine output shortness of breath anxiety Mild headache seizures increased sweating loss of appetite blurred vision tightness in the chest troubled breathing mood changes chest pain or discomfort muscle pain or cramps nervousness noisy breathing slow or irregular heartbeat headache vomiting sleeplessness slurred speech lightheadedness, dizziness, or fainting cool, pale skin shakiness dilated neck veins difficult or labored breathing unusual tiredness or weakness rash blue lips, fingernails, or skin irregular, fast or slow, or shallow breathing Diarrhea weight gain increased hunger cough coma increased thirst unusual weight gain or loss rapid weight gain fast heartbeat trouble sleeping nightmares