Botox and dermal fillers like, Sculptra are both injectable treatments. However, fillers differ in that they are used to fill in or plump up areas while Botox relaxes facial muscles. Fillers are used in soft tissue areas to restore the look of youthfulness by restoring volume as well as filling in folds and wrinkles. Botox is injected into the muscle and designed to relax the one causing the wrinkle to show.