Yes, though experience with other stocks tells me that broths made stovetop vs in an Instant Pot never taste the same, so I prefer stovetop broths. However, it's possible, but I would suggest following an Instant Pot pho recipe as a guide for instructions, and you can use my mix of seasonings and spices instead. I would use slightly less water to account for the lack of evaporation, start with 3 L instead of 4.