This can depend on your specific risk factors as well as the nature of any polyps found during your screening. The U.S. Preventive Services Task Force recommends colonoscopy screening every 10 years for adults 45-75 years old, but our experts may recommend more frequent screening if any concerns are found. Also if you have a family history of colorectal polyps or cancer, you may need to be screened earlier and more frequent. Your South Denver GI doctor can give you the best idea of when to return for your next screening at our Castle Rock Endoscopy Center, South Denver Endoscopy Center or Ridgeview Endoscopy Center.