Yes. Stress can cause fibroids that were once asymptomatic to grow at an alarming rate. To handle stress, the brain tells our body to produce extra hormones. As a result, hormone levels rise, which stimulates fibroid growth and causes symptoms to flare up. Chronic stress affects your health in numerous ways, causing everything from sleeplessness to depression, headaches, cardiovascular and reproductive issues, heart disease, diabetes, high blood pressure, and even fibroid growth.