-HPV (human papilloma virus): Contact with HPV 16 (a sexually transmitted disease) has been found to be linked to certain oral cancers.-Age: Oral cancer risk increases with age; It is predominantly seen in people 40 and over.nn-Tobacco: Major risk factor of oral cancer. Majority of cases are associated with some form of tobacco use (including chewing tobacco).nn-Alcohol: Heavy alcohol consumption increases the risk of oral cancer and those risks are even greater with combined use of alcohol and cigarettes.nn-Diet: A diet that lacks proper nutrition such as vegetables and fruits can increase the risk factor of oral cancer (as well as other types of cancer).