Sculptra is generally safe and well-tolerated, however, adverse events can occur.   Occasionally, Sculptra results in delayed occurrence of small papules or nodules in the treated area. These may develop 3-6 months after treatment. Papules are usually not visible, pose no risk, and usually resolve spontaneously on their own.   Rare but serious adverse events include possible occlusion of blood vessels, ischemia, infarction, or infection.