In principle, most of the wireless mice on the market accept the customization of their buttons. This is especially interesting in the case of ambidextrous mice. In this way, it does not matter if the user is right-handed or left-handed. It will be enough to change the mouse to the side and configure the buttons appropriately for each person. In the case of gaming mice, it will depend on the design of each mouse and each video game. Tentatively, the extra buttons on gaming mice should be customizable as well. However, due to the wide range of models that exist, it is advisable to make sure before choosing one.