Nociceptive pain: pain is caused by stimulation of sensory nerve fibres that respond to stimuli approaching or exceeding harmful intensity (nociceptors) and may be classified according to the mode of noxious stimulation. The most common categories are “thermal” (eg: heat or cold), “mechanical” (eg: crushing, tearing, shearing, etc) and “chemical” (eg: iodine in a cut or chemicals released during inflammation). Some nociceptors respond to more than one of these modalities and are consequently designated polymodal. Nociceptive pain typically changes with movement, position and load. Common Examples: Osteoarthritis Ankle sprain Rheumatoid arthritis