BOTOX is well-known for its ability to smooth wrinkles. However, it doesn't plump hollowed areas of the cheeks, nor can it lift sagging skin. For that reason, if you're considering a nonsurgical approach, you may want to consider dermal fillers to complement the effects of BOTOX. Dermal fillers contain compounds that plump the skin, add volume to hollowed cheeks, and smooth lines and wrinkles for a more youthful facial contour. This combination of injectable treatments is sometimes referred to as a nonsurgical facelift.