It depends on which form of the drug you use, and the advice of your healthcare team. For example, the FDA says it remains unknown if taking Fiorinal with Codeine presents a risk to mother or fetus, but that it should only be given when clearly needed. Researchers know that butalbital crosses the placenta and your child could develop a drug dependency, and there is some evidence that its use is linked to congenital (born-with) heart defects, but more study is needed. An alternative may be the better option.