A genome-wide CRISPR-Cas9 knockout screen to identify genes essential for lysosome function. Credit: Weichao Zhang et al, Nature Communications (2022). DOI: 10.1038/s41467-022-33025-1 In a rare disease called mucolipidosis type II, people’s hearts and abdomens swell, and their bones grow malformed. A lysosomal storage disorder, mucolipidosis type II causes edema ...
View more: Missing pathway in lysosome underlies newly discovered human disease