The kidneys perform the majority of the work related to eliminating metabolites of mushrooms from the body. They serve it swiftly. Studies suggest that the magic mushroom metabolites are almost unnoticeable in urine for 24 hours after the fact. But, it's essential to be aware that this might differ for all people. For instance, the rate could change dramatically for someone who suffers from impaired kidney function. Magic mushrooms are composed of two main active ingredients Psilocin and Psilocybin. The human liver metabolizes Psilocin into Psilocin. This is then excreted via urine. When analyzing urine samples for psychedelic mushrooms, Psilocin is also what test labs look for when analyzing urine sample.