With proper care and maintenance, All-on-4 and All-on-6 dental implants can last a lifetime. The implants themselves, which are made of titanium, become permanently fused with your jawbone. The prosthetic teeth attached to the implants typically last 10-15 years before needing replacement due to normal wear and tear. Regular dental check-ups and good oral hygiene practices can help extend the life of both the implants and the prosthetic teeth.