The volume of the BRAND PD-Tips are recognized by the HandyStep touch, AutoRep E and Repetman (patented PD-Tip size recognition). But they also can be used with HandyStep S, the Multipette 4780 and AutoRep M without recognizing the volume. When working with an dispensing system that is not mentioned above you should request samples of PD-Tips in different sizes from us and test the compatibility.