Now this is something that you must gauge for yourself. While there’s no such thing as a ‘weed overdose’, smoking too much of it might want to make you throw up sometimes. However, the best way to know you’ve had enough is when you start feeling sufficiently high. Remember to take it slow and easy as weed does take some time to ‘hit’ you. However, when it comes to medicinal marijuana, the doctor who prescribes you the weed will tell you exactly how much you’re supposed to consume and how. We strongly advise you to follow that.