There are various reasons for liver failure. Some of the important reasons are stated below.Drug overdoses may cause liver cells to die like large doses of Acetaminophen can cause liver failure.Infection caused by viruses like Hepatitis A, B, and E which is known as ‘Cytomegalovirus’ or  CMV may also lead to liver failure.Many of the industrial toxins like Carbon tetrachloride(CCl4) may lead to liver failure.In this type of autoimmune disease, the immune system of our body attacks the liver and causes liver failure.