The difference between hemp isolate, full spectrum, and distillate simply put is how much of the whole plant it contains. CBD isolate is isolated from all other cannabinoids and is considered the purest form of CBD. CBD Distillate, also referred to as broad-spectrum, still has the whole plant benefit of full spectrum oil without any THC. Full Spectrum CBD oil is the most complete and contains all the cannabinoids, including trace amounts of THC, terpenes, and other whole plant compounds.