The vast majority of DED patients have evaporative dry eye caused by meibomian gland dysfunction (MGD). MGD is a chronic condition, caused by terminal duct obstruction and/or changes in glandular secretion, which affect the stability of the tear film lipid layer. Current treatment options for DED with MGD include: artificial tears, warm compresses, eyelid scrubs, punctal plugs, eye drops, omega-3 fatty acid supplements, and oral medication; yet many patients do not achieve complete or long-term relief with these treatments.