Lip flip treatment causes very little discomfort to patients. Usually, you can avoid any pain from an injection by applying ice immediately before it. Topical numbing cream can also be applied to the area, but it is not usually necessary. It is recommended that patients refrain from exercising the rest of the day and avoid sleeping face down that night. It is normal for patients to have a small bump at the site of injection for a few hours after treatment. Due to the very small size of the needle, bruises are rare.