The main differences between the LG 22MP68VQ and LG 22MK600M monitors lie in their product lines, design aesthetics, and specific features. While both monitors typically offer a 21.5-inch screen size and Full HD (1920 x 1080) resolution, they may have variations in design, bezel size, stand features, and connectivity options. The 22MP68VQ is part of LG's MP series, and the 22MK600M is part of LG's MK series, which might offer different integrated technologies and additional features.