Vo filme V tom dome straší hrajú Mitchel Musso (DJ (voice)), Sam Lerner (Chowder (voice)), Spencer Locke (Jenny (voice)), Steve Buscemi (Nebbercracker (voice)), Maggie Gyllenhaal (Zee (voice)), Kevin James (Officer Landers (voice)), Nick Cannon (Officer Lister (voice)), Jon Heder (Reginald "Skull" Skulinski (voice)), Jason Lee (Bones (voice)), Catherine O'Hara (Mom (voice)), Fred Willard (Dad (voice)), Kathleen Turner (Constance (voice)), Ryan Whitney (Little Girl (voice)), Woody Schultz (Paramedic #1 (voice)), Ian McConnel (Paramedic #2 (voice)), Erik Walker (Bully #1 (voice)), Matthew Fahey (Bully #2 (voice)).