The best way to ensure a comfortable ride is to make sure your bike is adjusted as precisely as possible to your body measurements. The seat height should be set so that when your front leg is fully extended on the pedal, there is a slight bend in your knee and the seat angle should be level. The handlebars should be adjusted so that you can hold a comfortable bent-elbow position and still use all the handle positions easily. This will help you avoid neck, shoulder, and wrist pain. Gel seat covers that slip on over the standard saddle and padded cycling shorts are another way to add comfort to your workout.