Vo filme Wendy and Lucy hrajú Michelle Williams (Wendy), Wally Dalton (Security Guard), Will Oldham (Icky), John Robinson (Andy), David Koppell (Kid by Fire), Max Clement (Kid by Fire), Sid Shanley (Kid by Fire), Dave Hubner (Kid by Fire), Michelle Worthey (Sadie), Roger D. Faires (Recycler in Wheelchair (as Roger Faires)), Boggs Johnson (Recycling Man), Tanya Smith (Grocery Checker), Michael Brophy (Grocery Store Stocker), John Breen (Mr. Hunt), Deneb Catalan (Male Cop), Skeeter Greene (Female Cop), Marilyn Faith Hickey (Police Administrator (as Marilyn Hickey)), Jeanine Jackson (Grocery Cashier), Brenna Beardsley (Grocery Cashier), Winfield Jackson (Teenager by Car), Gabe Nevins (Teenager by Car), Connor O'Shea (Teenager by Car), Josh Larson (Teenager by Car), Ayanna Berkshire (Pound Employee), Dan Wilson (Man on Bus), Greg Schmitt (Mechanic in Garage), Will Patton (Mechanic), David Rives Curtright (Man Reading Book), Larry Fessenden (Man in Park), Holly Cundiff (Security Guard's Woman), Lucy (Herself), James Yu (Cab Driver), George Haapala (Home Owner), Deirdre O'Connell (Deb (voice)), M. Blash (Dan (voice)).