The simple answer to this question is yes but let’s dive a little deeper into the anatomy of the question. First off, understand that meat and poultry are composed of naturally occurring water. When they are frozen and they begin to thaw, there will be condensation as a result. Now, when this happens, it is probably going to run off of the defrosting board and onto your countertops and possibly even the floor.
While there is nothing you are going to do to stop the condensation, you can ensure that it does not leave you with a mess to clean afterward (even though the mess will be easy to clean, regardless). Anyway, this is where a drip pan comes in handy as they are designed to collect condensation, grease, and various other liquids.