There are column extraction method, paramagnetic particle method and one-step extraction method for RNA virus extraction. The paramagnetic particle method and column extraction method can be divided into manual operation and automatic machine operation. Generally, original liquid specimens are taken for extraction. The automatic paramagnetic particle extraction is characterized to be the best effect, with the advantages such as safe and convenient operation, large extraction amount for one time, high extraction efficiency and the best subsequent amplification effect. Therefore, it is recommended to use the paramagnetic particle method with an automatic machine to extract 2019-nCoV nucleic acid for the subsequent PCR amplification experiment. The specific instrument and magnetic particle reagent are with reference to the instructions of each manufacturer.