To create a sense of familiarity in your design using UX psychology, focus on incorporating elements that users are accustomed to seeing in other applications or websites. This can include using standard icons, intuitive navigation, and a consistent layout. Additionally, consider using psychological principles such as the mere exposure effect, which states that people tend to develop a preference for things merely because they are familiar with them. By incorporating familiar elements and psychological principles, you can create a sense of comfort and ease for your users, leading to a better user experience.