Earthworms can have different kinds of diseases that can lead to the worm's death. These can include viral infections such as Mysore, which is caused by the parasitic soil nematode. They can also be caused by bacteria, fungi and protozoa (single-celled animals).because of earthworms ' sedentary lifestyle, they're very prone to diseases and are often more susceptible to bacteria and protozoa. because of earthworms ' habitat, they are constantly in contact with their 'endocrine glands' and can develop problems. For example, earthworms have a very sensitive nervous system and infection can cause them to become weaker, leading to an early death.