We find that some people can keep one in place all night with no problems, while others (not many but a few) find they can only wear it for part of the night. If this is the case for you, then try reheating and remoulding your SleepPro for a better fit.Try upgrading to a SleepPro custom. These are made using a dental impression kit that provides a near perfect fit to your teeth and substantially reduces the likelihood of it dropping out of your mouth while you are asleep. They are also more comfortable.Some people find they cannot sleep with a mouthpiece in their mouth. If this is the case for you, it is worth noting that people get used to wearing a mouthpiece with time.