Tire stagger refers to the difference in circumference between the left and right side tires on a go-kart. Stagger is used to help karts turn more effectively, particularly on oval or banked tracks. The kart can maintain a smoother line through corners by having a larger tire on the outside and a smaller tire on the inside. It's essential to consult your kart manufacturer or an experienced racer for guidance on the optimal tire stagger for your specific setup and track conditions.