The softest bone in the human body is cartilage, i.e., Tongue. Yes, the Tongue itself contains a soft bone that doesn't seem like a bone. So, humans generally ignore to consider the Tongue has a bone. The Tongue is the most crucial organ in the gustatory system used to sense taste. It contains pink and moist soft tissue known as the mucosa, on which there are many taste buds. The coarse texture of the Tongue of vertebrates is due to papillae, tiny bumps on the Tongue.