After a diagnosis of chronic illness, people may feel “broken,” and wonder in particular if they can maintain an active sex life. Clinicians generally agree that, for most patients, the positives of sex outweigh any negatives or limitations, and suggest keeping in mind that all relationships face challenges. In practical terms, shifting a couple's focus from penetrative, or performance-based, sex toward pleasure-based sex that involves a wider range of intimate activities, can often creatively accommodate for limitations and still provide satisfaction and connection for partners.