National Prescription Drug Take Back Day is an initiative led by the DEA in the United States. It occurs in April and October of each year to help address the drug overdose epidemic and promote community safety and health. The DEA encourages the public to remove unneeded medications from their homes as a measure of preventing medication misuse. The next National Prescription Drug Take Back Day will take place on October 28, 2023. Here are some steps individuals can take to help prepare for Drug Take Back Day: Locate all medications in your household and ensure that they are securely stored. All lids should be tightly secured on bottles and away from the reach of children and pets. Conduct an inventory of the medications and identify which are unwanted and/or have expired dates. Clearly label medications that need disposal. Take the medications to a Drug Take Back Day collection site between 10:00 a.m. and 2:00 p.m. Use the DEA collection site locator to locate the closest Drug Take Back Day collection site. Many communities also have year-round drug take-back programs.