We would not call them disadvantages but, rather, reservations that can be resolved. 1) Expensive real estate. Though this is true in Singapore, it is quite possible to find some moderately priced listings. Anyway, after your business matures, this challenge will not seem too significant. 2) High salary expectations of local staff. Unless your business involves manufacturing capacities in Singapore, this restriction is not critical. 3) Limited domestic market. If your business is in the banking/financial sphere or focused on the international market, this observation does not matter. 4) Advanced requirements of banks. This peculiarity is typical for all developed jurisdictions. The situation is more favorable in classic offshore jurisdictions, but they also have some reservations.