The cost of sewer drain repair varies depending on the severity of the issue, the repair method, and your location. Basic repairs, such as clearing a blockage, can cost between $100 and $300. More extensive repairs, like fixing a broken or collapsed pipe, can range from $1,000 to $4,000. Trenchless repair methods, which are less invasive, typically cost between $4,000 and $15,000. It's best to get multiple quotes from professional plumbers to understand the specific costs for your situation.