Cold sores, also known as fever blisters, are small, painful blisters that typically appear on the lips, chin, or cheeks. Here are a few things you can try to help reduce the duration and severity of cold sores: Use a lip balm with sunscreen: Applying a lip balm with sunscreen can help protect your lips from the sun, which can trigger cold sores. Apply a cream or ointment: There are many over-the-counter creams and ointments that can help reduce the duration and severity of cold sores. Take an over-the-counter pain reliever: Pain relievers like acetaminophen and ibuprofen can help reduce pain and discomfort associated with cold sores. Apply a cold, wet compress: Placing a cold, wet compress on your cold sore can help reduce pain and swelling. Avoid touching or picking at your cold sore: Touching or picking at your cold sore can increase the risk of infection and further spread of the virus. Avoid sharing cups, utensils, and towels: Cold sores are caused by the herpes simplex virus, which can be transmitted through close contact.