In most cases, you can receive the non-live flu shot while taking Entyvio, but you should not use the live nasal flu vaccine (FluMist) unless approved by your doctor. Always get approval from the doctor who prescribed your Entyvio before getting any vaccination. Because Entyvio can suppress your immune system, it may increase your risk of infection with live vaccines or the vaccine may not be as effective. Before you start treatment with Entyvio, talk to your doctor so you can be brought up to date with all needed immunizations as recommended.