The simple answer is yes, you can get a tattoo while on acne medication. The more complicated answer is that it really depends on the type of acne medication you are taking. If you are taking a topical cream or gel, such as benzoyl peroxide, it is unlikely to cause any problems. However, if you are taking an oral medication, such as isotretinoin (Accutane), there is a small risk that the tattoo ink could cause an allergic reaction. Therefore, it is important to talk to your doctor or dermatologist before getting a tattoo if you are taking oral acne medication.