Yes, chronic zinc deficiency has been known to cause madarosis. However, clinical deficiency of this nutrient is very rare and it is mostly encountered in people with severely restrictive diets (e.g. people with anorexia nervosa), certain genetic disorders or in those who receive nutrition through a gastric tube or an IV for extended periods [1]. Healthy people who eat well-balanced meals don’t normally experience zinc deficiencies so severe as to cause eyebrow or eyelash loss.