For the first dose, use one 5 mg spray in one nostril. If the seizure cluster continues for at least 10 minutes after the first dose, a second 5 mg dose may be given if your healthcare provider has instructed you to give a second dose. Give the second dose in the other nostril. If the seizures do not stop after Nayzilam is used, get emergency medical help right away (call 911). DO NOT give more than 2 doses to treat a seizure cluster.