Skinless, boneless chicken breasts are a real time-saver when you need to get dinner on the table fast. They are best cooked very quickly using high heat. Sauté whole boneless chicken breasts in a skillet, bake them in the oven, grill them, or cut them into strips for a stir fry. Brush a little oil on them to keep them moist. Cook to an internal temperature of 165°F. Be careful not to overcook. Boneless chicken breasts can dry out when cooked too long.