ClearLight’s technology is being developed to eventually evaluate true 3D relationships within a volume of diseased and normal tissue. By examining the tissue in a 3D volume, the CLARITY platform will allow a better understanding of the molecular heterogeneity within that tumor sample. The up and coming, Tru3D analysis software will be able to process image files of multiplex IHC stained tissues and analyzes the tissue sample in 3D. The current proprietary 3D Software workflow is Raw Data –> Cell Segmentation –> Classification –> Analysis. Samples in our published papers were imaged on a Leica SP8 confocal microscope and using Bitplane Imaris 9.2.1 software as this was prior to the development of our proprietary software. Learn More.