The main difference between these two treatments is that liposuction is a minimally-invasive surgery while Liposonix is not. Liposuction uses small incisions and a surgical cannula to break up fat deposits and remove then with a surgical vacuum. On the other hand, Liposonix uses ultrasound energy to damage fat cells so that the body can metabolize the cells and expel them. Liposonix comes with no downtime or incisions, but can be less cost effective and produce lesser results than liposuction since more than one treatment session is usually required.