The evolution of DBS has been characterized by advances in technology and a deeper understanding of brain targeting, essential for customizing treatment to individual patient needs. Innovations such as directional leads and adaptive DBS underscore the shift towards personalized care, allowing for precise brain targeting, potentially minimizing side effects and enhancing treatment effectiveness. Over the years, DBS has transitioned from a generic approach to a more refined, patient-specific strategy, paving he way to the modern era of DBS with improved targeting techniques.