CHF patients with NT-proBNP levels above 1000 ng/L need more intense care and their treatment plan has to be changed. Higher doses of medication (e.g., diuretics and b-blockers) are prescribed in view of NT-proBNP concentration falling. This treatment tactic reduces the likelihood of the person needing in-patient care due to the disease getting worse by up to 25-30%, and the heart function and well-being of the patient gets better.