In general, League of Legends, Counter-Strike, and Dota2 are three of the most popular esports titles for e-sports bettors, combining approximately 85% of the global betting volume. That, however, does not mean other titles are completely ignored by esports bookmakers, nor that they lack viewership.
For example, bet365, which has established itself as one of the most popular and best-rated sportsbooks in the world is also probably the best bookmaker for esports. It offers markets on numerous esports titles, including Rocket League, StarCraft II, Hearthstone, FIFA, NHL, NBA 2K, Rainbow Six Siege, Overwatch, Fighting Games, and more.