Purina Pro Plan and Purina ONE are both science-based pet food brands offering super premium nutrition. Pro Plan also offers a broader range of formulas—more than 90 formulas, compared to 30-plus formulas for Purina ONE. The extensive array of Pro Plan formulas provides more specific breed size and special need choices. For example, while Purina ONE offers two Large Breed dry dog formulas, Purina Pro Plan offers six Large Breed dry dog formulas including Adult 7+ Bright Mind, Adult Chicken & Rice, Adult Chicken & Rice Shredded Blend, Adult Weight Management, Puppy, and Adult Sensitive Skin & Stomach options. Pro Plan dry formulas typically feature higher levels of key nutrients, such as antioxidant vitamins, glucosamine, and fatty acids. Additionally, a larger number of Pro Plan dry formulas are fortified with live probiotics for digestive and immune health. Pro Plan formulas are premium-priced compared to Purina ONE but typically require lower feeding amounts. Lastly, Pro Plan is exclusively sold at pet specialty retail stores and online, whereas Purina ONE is broadly distributed across all retail channels.