Sulfasalazine is an older drug and tends to be more affordable, at $20 a month. Colazal (balsalazide) may be under $100 a month. Oral mesalamine (such as Asacol, Lialda, Delzicol) can range in price from $100 to $300 a month, but some brands (such as Pentasa) may be $1,500 a month or more. Mesalamine enemas may cost about $200 a month. Dipentum (osalazine) may be $1,600 a month. There may be patient assistance programs available by contacting the drug manufacturer.