To avoid wasting label sheets on incorrect layouts, the best practice is to conduct a thorough test print onto regular paper. First, ensure your document is correctly set up in Word with the accurate label size and layout. Print a test page using the same print settings that you will use for your final labels. After printing, take this test page and place it on top of your label sheet. Hold both against a light source to see if the printed addresses align properly with the individual labels on the sheet. This visual check allows you to adjust the layout or printer settings as needed. Repeat the test as necessary until you achieve perfect alignment, ensuring a professional outcome for your actual label printing.