The U.S. Department of Agriculture doesn’t allow a borrower to purchase a second home with a USDA loan, and they only approve mortgages for primary residences. That means you can’t have more than one USDA loan at a time. However, you could potentially get more than one USDA loan throughout your life. For example, let’s say that you purchase a home with a USDA loan. After a decade in the home, you decide to sell it. At that point, it’s possible you would qualify for another USDA loan for your new primary residence in a qualifying rural area.