The exclusion criteria in part consists of a history of severe allergic reactions, or uncontrolled asthma, the use of beta blockers, pregnancy, the use of immunosuppressant medications (e.g. chemotherapy etc.), uncontrolled hypertension or significant cardiopulmonary disorders (e.g. CHF, MI, cardiac arrhythmias or moderate to severe COPD), and those with extensive atopic dermatitis or psoriasis may not be good candidates for immunotherapy. An extensive allergy history will be taken on each patient before commencing allergy testing and immunotherapy.