Hi, Fioricet and Fiorinal are combination medications that contain acetaminophen, caffeine, and either butalbital (Fioricet) or aspirin (Fiorinal). While there may not be an exact generic equivalent to these medications, there are several similar medications that contain the same active ingredients. For example, Esgic and Esgic-Plus are brand-name medications that contain the same active ingredients as Fioricet and are sometimes used as an alternative. Similarly, Fiormor and Fiortal are brand-name medications that contain the same active ingredients as Fiorinal. However, it is important to note that while these medications contain the same active ingredients, they may have different inactive ingredients, dosages, or formulations, which can affect their effectiveness and tolerability. It is always best to consult with your healthcare provider to discuss the best treatment options for your individual needs and circumstances. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician