What I find when looking at waterjets, high velocity waterjets in lavage on biofilms, is that we have two things occurring. First of all, we do get some removal of the biofilm. We do see pieces of biofilm coming off and we do get quite a significant reduction of biofilm. However, biofilms can actually behave as liquids under certain circumstances such as when they are subjected to high shear stress. People donâ€t normally think about them as liquids. We think of them as sort of pieces of dirt almost, or solids. But biofilms can actually flow. So when biofilms are exposed to these high velocity jets, they can actually flow over the surface, and then when the jet is removed, then they can form back into biofilm. They have a viscoelastic property where they can just resume and carry on from where they left off. So Iâ€m pretty confident that it will remove a certain amount of biofilm, but I think thereâ€s also potential for even possibly spreading biofilm around to other places. You only start to see these effects when you use high speed imaging to look at these interactions, these fluid-biofilm interactions, to see this process occurring. Interestingly we can possibly use this time when they are liquefied to more effectively deliver more antimicrobial agents into the depths of the biofilm.