The symptoms of Peyronie's disease include: a thickened area or hard lump (plaque) in the shaft of the penis (it's rare to get more than one plaque) a curve in the penis when it's erect (usually it curves upwards) pain in the penis, usually during an erection (pain in the non-erect penis is rare) the penis looking misshapen, like an hourglass loss of length or girth of the penis Some men with the condition get pain in their penis, while others get none. If you do get pain, it may get better over time. But in severe cases, the curve in the penis can make having sex difficult, painful or even impossible. Peyronie's disease may also lead to erectile dysfunction. ::: body-ad-mobile zones:: 232632,232514,227375,232642 types:: 5 disclaimer:: ADVERTISEMENT typeFilter:: display adCount:: 1 :::