The recommended gap between the first and second doses of the HPV vaccination in a 2-dose regimen is 6–12 months, while the minimum delay is 5 months. If the second dosage is administered before 5 months, a third dose should be administered. The duration of protection provided by the vaccine lasts for 10 years. In order to be protected from all types of human papillomavirus (HPV), patients must receive both vaccines. However, those who have already been infected with one type of HPV can still be infected with other types of HPV later in life. Thus, people who have never been exposed to HPV but still want complete protection can also be given the vaccine. Those who have been vaccinated but were not completely protected could also be given another shot after observing them for 12 months. Those who have already been infected with HPV might not be able to fight off future infections because their immune systems have already gone through this process once before. However, those who have not yet been infected with HPV might be able to mount an effective response because they have not yet been exposed to the virus. Therefore, someone who has not been infected with HPV but wants complete protection could also be given the vaccine. It is important to note that although the vaccine protects against several types of HPV, it does not guarantee that patients will not get cancer caused by these viruses.