Prolotherapy is a treatment that can basically restart a healing mechanism. Unlike pain killers or cortisone shots, prolotherapy resolves your pain instead of numbing it. Cortisone is used to calm the immune system down. So if you inject it into an inflamed swollen joint, cortisone will usually calm down that inflammation, and all those signals that are being sent to your brain saying, "Hey, this is painful, don't walk on it," for example. The downside to cortisone is that it simply blocks normal healing mechanisms And using it long-term can cause other problems. It can sometimes cause people to forget that they are still injured and they think they can go run on it for example. That can cause more damage than if they didn't get any injection in the first place. The exact opposite is true with prolotherapy. Prolotherapy is a regenerative injection. It's a regenerative procedure and it's working with the body. It's not trying to calm the body down or completely blunt the body's response. It's responding with the body and telling it, "Hey we didn't heal right the first time, come back in, do your thing." And then you can feel safe going back to your favourite activities.