Loratadine and alcohol should not be combined. The elimination half-life of Loratadine is approximately 8 to 15 hours, which is the amount of time it takes for 50% of the medication to flush out of your body.[8]
The effects of Claritin should last approximately 24 hours which is when it may be safe to drink alcohol. However, individuals should consult their physician about when it would be safe to consume alcohol after taking Claritin.