Yes, you need to avoid grapefruit, grapefruit juice, and Seville oranges while you’re taking Imbruvica. These citrus juices and fruits can cause the level of Imbruvica in your body to increase. This can lead to serious side effects that may be dangerous to your health. (For more information, see the “Imbruvica side effects” section above.)
If you have any questions about foods or juices to avoid while taking Imbruvica, talk with your doctor.