There is no downtime associated PRP injections; However, after your treatment, your skin may be red. This is normal and to be expected. Redness usually lasts from one to 24 hours. You may also have a little swelling in some areas. Due to this, some patients like to be treated towards the end of the week, so they have the weekend to recover. Healing time varies from patient to patient. Healing may take longer if PRP injections are paired with micro-needling.