No. Ancho chili powder is made with just one ingredient - dried ancho chilies. This spice is flavorful but not hot. Standard chili powder is made with a blend of spices like cumin, garlic, and cayenne. Because a chili powder blend will have varying amounts of cayenne, heat levels will also vary. You can replace ancho chili powder with standard chili powder, but the seasoning and heat levels will be a little different.