Best practice would be to convert all to work with so make sure the s that are at least 15ppi (office digital laser printer) or better yet at least 3ppi (minimum for offset) at reproduction size. Scale crop manipulate edit your s. This manipulations described above since all (and only) the s you manipulate using InDesign Link tool; be sure to re to the in other locations. Also once it packaged be sure to open the copy of the InDesign files that is in the packaged folder and not the original version to make edits and updates (like reing). Create your PDF(s) from the packaged InDesign file. If you need to make PDFs that will be presented and read online copy the entire packaged folder rename it and the InDesign file within and revise that file and s (s to RGB. Your printingpany is the best source of advice for your file prep. They will undoubtedly have specs (and sometimes hacks) to help you help them produce spot-on color whether digital or offset on a variety of paper stocks and other substrates. Let them lead you and follow their advice. They know their equipment better than you do and how to get best results. Here the kicker. If color quality is not critical or youre using a mid- to low-end office printer that is unable to reliably print good color letting file conversion to CMYK occur in the export won hurt and might save some steps and time. But under those circumstances the color model won matter anyway since the reproduction tool lacks the ability to manage color nuance. And if you want to reprint with higher quality youll want to tweak the file. Easier to do the first time and produces better results.