Lemtrada helps most people with MS, but may have side effects in some people. All medications have side effects. It is important to notify your health professional if you experience any side effects or are feeling unwell.
Potential side effects of Lemtrada treatment include infusion-associated reactions, infections and development of autoimmune conditions.
Infusion-associated reactions, such as headache, rash, fever and nausea, are common and occur at the time of the infusion or within 24 hours after the infusion. Most infusion reactions are mild. To minimise the risk of these side effects, medications are given prior to infusion of Lemtrada and you will be monitored during and after the infusion so that any reactions can be managed.
Lemtrada increases your risk of getting infections. Infections are usually mild or moderate in severity but in some cases can be serious. You may have an increased chance of getting an infection caused by the bacteria Listeria. It is recommended to avoid food that might be a source of Listeria if you are being treated with Lemtrada.
Lemtrada can increase your risk of developing certain auto-immune conditions. These include thyroid disorders (overactive or underactive thyroid), immune thrombocytopenic purpura (a bleeding disorder, also called ITP) and, rarely, kidney disorders. These autoimmune conditions can develop many years after Lemtrada treatment and can be very serious if left undiagnosed and untreated. You will need to undergo regular (monthly) blood testing from before treatment starts and for four years after your last infusion to ensure that these conditions can be detected early and treated promptly.
Your health professional can provide comprehensive information on the use of Lemtrada, including precautions and side effects.