Hello, Please check for spontaneous splenic rupture conditions like Bartonella and Epstein Barr virus et cetera. Also, enlargement of spleen lead to diaphragm irritation which further leads to left shoulder pain. Please consult your physician, he will examine and treat you accordingly. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Penchila Prasad Kandikattu