Ibuprofen used regularly is not healthy. It does have adverse effects, though, particularly if taken in high dosages or for an extended period, like any medication. A few typical adverse effects are nausea, diarrhea, headaches, and dizziness. Certain people, particularly those with a history of heart disease or high blood pressure, may also experience an increased risk of heart attack, stroke, and other cardiovascular issues when using ibuprofen.