The terms self-quarantine, isolation, and shelter-in-place have been commonly used in regards to the COVID-19 pandemic, but it is important to understand the differences between these. Quarantine is defined as mandatory isolation or restrictions on where you can go, intended to stop a contagious disease from spreading. In the case of COVID-19, it applies to individuals who may have been exposed to the virus that causes COVID-19 and have been asked to stay at home under strict guidelines. Isolation applies to individuals who contract COVID-19. These individuals may be put into isolation in a hospital or at home. If isolated at home, it is recommended to have a designated bedroom and bathroom for the infected individual to use in an attempt to prevent others from getting sick. Shelter in place applies to a broader group of individuals, and can last for weeks or longer. It is not specifically related to confirmed exposure to the virus causing COVID-19. During this time, individuals may only leave home only for essential activities.