No, not really. This is all about the intonation range at the bridge, for instance a Tune-o-matic bridge. A heavy string gauge combined with down tuning can end up out of intonation range. Our steel-string acoustic fingerboards (650 mm and 630 mm scale) work fine with 0,011- to 0,013-set with a wound 3d string. For our nylon-string acoustic fingerboard (650 mm scale) you can use medium to hard tension strings. We have through the years tested a big range of string brands and noticed that plain nylon strings varies a lot in tension consistensy. We can recommend Savarez Corum strings