For a quick dinner, pull the frozen meatballs from the freezer and if you have time, bring to room temperature for an hour then bake on a parchment-lined sheet pan or pan saute and use them in your favorite dish. Internal temperature for turkey meatballs should be 165 degrees. You can also cook frozen meatballs right from the refrigerator, they might take slightly longer to cook depending on their size. Bake them at 400 degrees for 25-30 minutes.