Sometimes, a macroscopic examination of a sperm specimen shows a high percentage of round cells in addition to sperms. Normally, they are just bladder, prostate or urethral epithelial cells, immature germ cells, or white blood cells (leukocytes).
The presence of leukocytes indicates the presence of an infection, which could lead to alterations in other parameters. In this case, the semen analysis would be repeated after treating the infection with antibiotics.