Theoretically, the fastest Nike running shoes right now are the Alphafly 2s; these shoes combine the responsive ZoomX foam with two Zoom Air units at the front. Eliud Kipchoge wore an Alphafly prototype when he broke the 2-hour marathon record in October 2019.
That said, we would argue that the Nike ZoomX Vaporfly NEXT% is still the best choice for most runners who need fast Nike running shoes. The Vaporfly allows for more manoeuvrability than the Alphalfy, thanks to the lack of Air Zoom units. However, these units do a great job of providing better energy returns which will pay off over long distances.