Pre-dispersed ink is safer than powdered ink since it has less likeliness to get contaminated than powdered ink. Companies producing pre-dispersed ink use a sterile, secure, and hygienic environment to process the ink materials. Therefore, you do not need any preparation before use as it is readymade. But when you buy powdered ink, you have to prepare it yourself. If you cannot get the essential tools and surroundings to sterilize it, it will become spoiled anytime.