During autoclaving and sterilization, medical device manufacturers should be familiar with the effects of Gamma or E-beam radiation on plastics. The effects vary depending on the material. If used correctly, these radiation processes can result in the optimum functionality of the medical devices. During the process, the polymer chains rearrange to create high crystallinity. This results in a reduction in molecular weight. In addition, the enthalpy of fusion changes. Because of this effect, the polymer can increase in biodegradability.