From the official New Orleans tourism website..."Cajun and Creole food are both native to Louisiana and can be found in restaurants throughout New Orleans. One of the simplest differences between the two cuisine types is that Creole food typically uses tomatoes and tomato-based sauces while traditional Cajun food does not." More than that, Cajun seasoning typically uses garlic powder, onion, black pepper, and Cayenne pepper. Creole seasoning will add more herbs such as paprika, oregano, and thyme.