Heirloom tomatoes are different from regular tomatoes in that they are open-pollinated and have been cultivated for many generations. They come in a wide range of colors, sizes, and flavors, and have a more complex taste than regular commercially grown tomatoes. u003cbr/u003eHeirloom tomatoes are not genetically modified, and are often grown using organic methods. u003cbr/u003eThey are also more fragile than regular tomatoes and have a shorter shelf life.