Excessive burping is not typically a sign of cancer, but in rare cases, it could be related to cancers that affect the digestive system, such as stomach or esophageal cancer. However, frequent burping is more commonly associated with less serious digestive issues like indigestion, gastroesophageal reflux disease (GERD), or certain dietary factors. If burping is accompanied by other concerning symptoms like unexplained weight loss or persistent stomach pain, it may warrant further investigation.