-Stable head-fixation of an awake mouse; -No general anesthesia during habituation/training or imaging/recording; -Efficient stress reduction due to the flat floor and natural cage environment; -Natural tactile stimulation (cage floor and walls); -Visual stimulation and integration with VR is possible but not required; -The mouse controls its own movement; -Standard size Mobile HomeCage is compact, compatible with the majority of commercial microscopes; -Mobile HomeCage Large is the only head-fixation system that allows using real (not virtual) mazes; -The locomotion tracking device (built into the air dispenser) allows monitoring behavior .