Abdominal pain: Individuals with Crohn’s disease often experience persistent, crampy abdominal pain. Diarrhea: Chronic diarrhea is a common symptom, sometimes accompanied by blood or mucus. Weight loss: Unintentional weight loss may occur due to decreased appetite and nutrient malabsorption. Fatigue: Chronic inflammation and nutrient deficiencies can lead to fatigue and low energy levels. Bowel irregularities: Crohn’s disease can cause bowel movement changes, including urgency or a feeling of incomplete evacuation.