Multiple clinical studies have shown that antioxidants and minerals such as beta-carotene, vitamins C and E, zinc, and copper can be beneficial for slowing the progression of intermediate-stage AMD to late-stage AMD. Based on these study findings, an AREDS2 formula containing vitamin E, beta-carotene, zinc, copper, lutein, omega-3 fatty acids, and zeaxanthin can be given as supplements to slow the progression of macular degeneration.