Ans. Yes, there have been many famous games played using the Ruy Lopez. One notable example is the 'Immortal Game' between Adolf Anderssen and Lionel Kieseritzky in 1851, where Anderssen sacrificed his queen to deliver a stunning checkmate. Another famous game is the 'Game of the Century' between Bobby Fischer and Donald Byrne in 1956, where Fischer showcased his exceptional tactical skills.