The long-term use of Semaglutide for weight management or glycemic control is not well studied beyond 2 years, but it may be a viable option for some individuals to manage chronic conditions over an extended period of time. However, the decision to continue Semaglutide treatment should be made in consultation with a healthcare provider and based on an individuals specific health needs and goals. Regular monitoring of metabolic parameters, including blood sugar levels and kidney function, is recommended for individuals on long-term Semaglutide therapy.