Labial adhesions are a condition in which the inner folds of the female genitalia (labia) temporarily grow or adhere together. This condition is most common in young girls aged between 3 months to 6 years, and it is related to hormonal influence. Labial adhesions usually occur due to inflammation of the skin, which causes the labia to stick together. Poor genital hygiene and bacteria in the area can also contribute to labial adhesions. Keeping the area clean and dry is essential for the treatment and prevention of labial adhesions. Symptoms of labial adhesions are usually minimal, and most cases are asymptomatic. However, post-void dribbling may occur due to labial adhesion. Urinary tract infections are rare with labial adhesion. Estrogen cream is the primary treatment option for labial adhesions. A trial of estrogen cream is usually initiated, and parents need to apply the cream twice a day for 2-8 weeks, as directed by the urologist. A small pea-sized amount of cream is applied to the middle of the adhesion, followed by slight pressure with the finger. In some cases, doctors may recommend separating the labial adhesions in the office with topical anesthetic (numbing cream). However, this procedure is occasionally done under general anesthesia in the hospital. After the adhesions are resolved, preventing their recurrence is essential. It is recommended to apply a thin layer of estrogen cream on the area every night for at least a month. There are a few risks associated with treating labial adhesions. In rare cases, skin infections and allergic reactions may occur. Additionally, estrogen cream can cause vaginal itching or burning. Parents must speak to their urologist if their child experiences any adverse reactions. In conclusion, labial adhesions are a common condition in young girls, but they usually resolve with minimal intervention. Estrogen cream is the primary treatment option, and parents must maintain good genital hygiene to prevent their recurrence. While there are some risks associated with the treatment, the benefits typically outweigh the risks. It is important to consult with a urologist for proper evaluation and management of labial adhesions.