No, disabling your antivirus software does not make using KMSPico safe. While turning off antivirus software might prevent it from flagging KMSPico as a threat, it does not mitigate the inherent risks associated with using such tools. KMSPico often contains malware or other harmful components that can compromise your computer’s security regardless of your antivirus settings. It is always recommended to use legitimate methods for software activation to avoid these risks.