Yes. In fact, the soothing formula of the CALM 1% BHA Sensitive Skin Exfoliant works with any topical prescription medication used for managing symptoms of rosacea. Apply the CALM 1% BHA Sensitive Skin Exfoliant after cleansing and toning and then follow with your nighttime moisturiser (or apply as directed by your doctor). It’s also an option to apply your prescription product at night and the 1% BHA during the day. For daytime, be sure to follow with a broad-spectrum sunscreen. If new to salicylic acid, start with 2-3 times per week and work up to daily application as needed.