Biscuits can turn out lopsided because of the way you pressed, rolled, or cut the dough (I know, not incredibly helpful). To prevent lopsided biscuits, press straight down and back up with a well-floured biscuit cutter. And if you cut square biscuits with a knife, trim the edges of the rolled-out dough to create straight sides. Then cut the individual biscuits. And be sure to flour the knife or cutter heavily before each pass.