Previous refusals always make the next application more difficult. If the application was refused because you provided false information, you may be banned from applying again and all subsequent applications may automatically be refused. If the reason for refusal was not meeting the requirements of the rules, you will have to demonstrate that your circumstances have changed. If an application for extension of leave to remain made in the UK is refused after the previous visa expired, you will most likely have to leave the country and make a fresh application from abroad. You will need advice from an immigration lawyer to confirm if there is an option of applying from the UK and how this will affect your right to work.