The term “ready to use” or “ready to fill” describes containers that have undergone washing, depyrogenation, packaging and a final sterilization process using gamma irradiation, EtO or autoclave sterilization. The packaging typically consists of a plastic nest that holds each individual and is located within a plastic tub. A loose sheet of Tyvek, referred to as a “liner”, is placed over the tops of the containers within the nest and the tub is sealed with another Tyvek sheet, often times called a “lid”, to seal the sterile containers until it is removed prior to aseptic filling. The advantages of getting containers in this pre-sterilized state include eliminating expensive equipment that has to be purchased with the filling machine to wash and depyrogenate the containers before filling. One must also consider the facilities, utilities and personnel activities that are required to support the process of preparing containers to receive the sterile drug product. The Water for Injection (WFI) system, cleanroom space, maintenance and validation for these systems all go away. This enables a simple and more nimble manufacturing environment with less infrastructure and support requirements. There are many commercially available RTU options available for syringes vials and cartridges from several reputable suppliers including; Ompi, SiO2, Schott, Becton-Dickenson, and West to name a few.