No, but most problems happen when paint cures inside the machine, so you need to clean up as soon as you finish painting. The tricky part is the paint nozzle, though reversible models make the job easier.The manufacturer of your paint sprayer will have cleaning instructions, and there's also plenty of useful information online. It is a bit time consuming, but so is cleaning ordinary paint rollers properly. Don't try to take shortcuts. Professionals tell us that most painting problems come from equipment that hasn't been cleaned and maintained properly. Following the procedure carefully will help ensure even coatings the next time you spray, prolong the life of your sprayer, and reduce paint wastage. Once a job is finished, filling your airless paint sprayer with water or storage solution is often recommended.