Yes, Notox is a great primer for foundation, so your foundation may even look better. We recommend using the directed amount of Notox (1 pump for eyes and face) followed by a moisturiser before applying makeup. The moisturiser provides a protective layer so that the natural bioactives in Notox are not mixed with any chemicals that may be in your makeup. The chemicals won’t cause harm but they may not let the natural bioactives work as well if they are mixed together.