If you've got a toilet paper rash, it can be difficult to know what to do. You can clean the area with mild soap and water, then apply a topical steroid cream if necessary. This will reduce inflammation and keep your skin hydrated, so it doesn't become irritated again. In addition to these steps, use a barrier cream or diaper cream on the affected area until it heals completely. These products will help protect your skin from further damage while keeping it moisturized so that it doesn't crack or split when you come into contact with something else, like clothing fabric or toilet paper.