The nicotine contained in vaporizers and e-cigarettes can raise blood pressure, adrenaline levels and heart rate, and researchers have linked its usage to asthma and chronic obstructive pulmonary disease. E-cigarettes and vapes also contain diacetyl, an organic compound with a buttery flavor that is used as a flavoring agent. The Centers for Disease Control and Prevention have stated that e-cigarette or vaping product use-associated lung injury (known as â€œEVALIâ€) has affected more than 2,500 people and has been associated with numerous deaths.