The main difference between PRP (Platelet-Rich Plasma) microneedling and stem cell microneedling is the type of healing tools used. In severe skin cell damage, stem cell micro needling helps tissues grow back, and skin look younger. This may offer a broader range of regenerative potential. PRP microneedling, on the other hand, uses the patient's own Platelet-Rich Plasma along with microneedling. The growth factors and platelets in the blood are used to encourage collagen creation and tissue repair right where the treatment is being done. The goal of both treatments is to improve the structure and look of the skin, but they do so in different ways. Which one to choose depends solely on your skin condition and your dermatologist" 's recommendation.