There are many different causes for a woman to not be sexually active, including: • Emotional causes, such as: • Stress • Relationship problems • Depression or anxiety • A memory of sexual abuse • Unhappiness with body image Physical causes, such as: • Hormone problems • Pain from an injury or other problem • Aging, which can cause vaginal dryness • Taking certain medicines, as some medicines for anxiety, depression, and seizures may cause sexual problems Any of these causes may result in: • Having less desire for sex • Having difficulty feeling aroused • Not being able to achieve an orgasm • Having pain during sex