Keep the unopened Saxenda pens in the refrigerator at a temperature of 36°F to 46°F (2°C to 8°C). Once you start using a pen, store it in the refrigerator or at room temperature, ranging from 59°F to 86°F (15°C to 30°C). Dispose of pens used for 30 days, even if medication is left in them. Avoid freezing Saxenda.