No. Around the world, sucralose has been confirmed safe. It is approved for use in over 80 countries, is used to sweeten over 4,000 food and beverage products and provides sweetness in some medicines and medical foods.
Additionally, in 2019, the International Agency for Research on Cancer (IARC) shared that sucralose safety tests have indicated no harm at when looking at sucralose consumption levels well above expected human intakes. IARC also downgraded sucralose to low-priority in the IARC Monographs 2020-2024, stating that there are no studies on sucralose of cancer in humans.