Nicotinamide is one of the more widely used clindamycin gel combination treatments. It is a form of vitamin B that helps to reduce the inflammatory symptoms of acne, which in turn reduces redness and tenderness. So not only does it help to reduce the visible symptoms, it also feels less tender.
Clindamycin is usually the first line of treatment in treatment of acne. A clinical study reveals that 4% nicotinamide gel works as effectively as 1% clindamycin gel in treatment of inflammatory acne. 82% of patients using 4% nicotinamide gel and 68% using 1% clindamycin gel noticed improvements after 8 weeks of treatment. [popover id=ref4] So, nicotinamide gel can be rightly considered as an alternative treatment for acne vulgaris.