As of Sep 30, 2022, the average annual pay for an Infection Control Nurse in the United States is $87,562 a year. Just in case you need a simple salary calculator, that works out to be approximately $42.10 an hour. This is the equivalent of $1,683/week or $7,296/month. While ZipRecruiter is seeing annual salaries as high as $141,500 and as low as $53,500, the majority of Infection Control Nurse salaries currently range between $71,000 (25th percentile) to $98,000 (75th percentile) with top earners (90th percentile) making $126,500 annually across the United States. The average pay range for an Infection Control Nurse varies greatly (by as much as $27,000), which suggests there may be many opportunities for advancement and increased pay based on skill level, location and years of experience.