Human mesenchymal stem cells (hMSCs) are adult, multipotent stromal cells with the capacity to differentiate into mesodermal lineages including osteocytes, adipocytes, and chondrocytes, as well ectodermal (neurocytes) and endodermal lineages (hepatocytes). HMSCs are self-renewable (up to six passages), easily accessible, and cultures can expand in vitro with exceptional genomic stability. They have an adherent, fibroblast-like (spindle-cell phenotype), shoal-like pattern.
Positive markers: MSCs have a specific set of cell surface markers (CD73, D90, CD105).  HMSCs are non-hematopoietic.
Negative markers: MSCs lack expression of CD14, CD34, CD45, and human leucocyte antigen-DR (HLA-DR).