We have not specifically looked at other post-translational modifications such as lipidation.  Cell-Ess can improve the lipid membranes including those of the ER and Golgi. Therefore, theoretically there should be a benefit in using Cell-Ess for lipidated proteins, but we have not tested it yet.  Lipidation, similar to glycosylation, is a complicated multistep process where Cell-Ess can most likely play a role, but we look forward to hearing from users who have directly tested what their experiences have been.