If issues are found during a home inspection, it's important to communicate them with the seller and discuss possible solutions. While negotiating is always an option, the extent to which you can negotiate depends on various factors, such as the severity of the issue and local market conditions. If the problems discovered are minor or cosmetic, you might suggest that the seller addresses those items before closing or compensate you with a credit at closing. However, your negotiation strategy should differ if significant issues require major repairs. Be prepared to use expert opinions from professionals in related fields, such as contractors or home inspectors themselves, to support your claims while negotiating with the seller. Remember that both parties have a common goal of completing the sale, so approach negotiations respectfully and professionally to create a mutually beneficial agreement.