Best answer: Absolutely! Even if you're using a tempered glass screen protector or something with more bulk, Apple's Smart Battery Case doesn't interfer with the screen's edge enough to mess up your screen protector. Plus, the material the Smart Battery Case is made from is flexible enough to slip over any edge-to-edge screen protectors.For iPhone XS: Smart Battery Case ($129)Screen protection: iamFilm Tempered Glass Screen Protector ($8)