You have not mentioned in your query whether your wife has met a psychiatrist herself or not. The first step would be to encourage her to seek treatment and then involve her family. In order to make a complete diagnosis it is very important for her to consult the doctor. In case she is diagnosed as having these difficulties, then it is essential that she gets treatment. These problems need professional treatment, which involves counselling and medication. Her family then may need information on these conditions so that they can recognise the gravity of the problem. You may want to ask them to accompany you to the doctor who can then explain the conditions better.