Although the Venefit Procedure (radiofrequency based) has enjoyed excellent patient comfort ratings, both techniques are very effective in achieving successful long-term closure of the saphenous vein trunks and its branches. Laser endovenous closure may be more appropriate in cases where there are segments of veins less than 7 cm in length that need to be closed, or when the diameter of the vein to be treated exceeds the recommended limit for radiofrequency closure. Treatment decisions should be individualized based on clinical and anatomic factors.