The RooYard Cordless Paint Sprayer is compatible with a wide range of paints, including latex, enamel, oil-based, acrylic, and water-based paints. It is also suitable for varnishes, stains, and sealers. However, it is recommended to check the paint viscosity and adjust it as necessary to ensure smooth and even spraying. Thicker paints may need thinning for optimal performance.