Not necessarily. Kybella and CoolMini both work by permanently removing unwanted fat cells, just in different ways. Some patients prefer one to the other. Discussing the benefits of both Kybella and CoolMini is something that can take place during your complimentary consultation. Kybella tends to be a better choice for fine-tuning and contouring, while CoolMini is a good option for debulking larger adipose tissue (fat) pockets, that is why they are both used in many cases as a combination treatment, delivering superb results.