Whether or not irregular periods can be cured ultimately depends on the underlying cause for your irregular menstrual cycle. With that in mind, if you are experiencing irregular periods due to stress or lifestyle factors, you can likely fix the problem with healthy stress management techniques or by making changes to your lifestyle habits. Likewise, if your irregular menstrual cycles are a side effect of the medication you are taking, you can cure this side effect by stopping the medication or switching to a new medication. In the case that the irregular menstrual cycle is caused by an underlying condition, the possibility of curing the problem depends on whether or not the underlying condition can be cured or effectively treated to eliminate the symptom of irregular periods. Some conditions causing irregular periods that can be cured include hyperthyroidism, hypothyroidism, uterine fibroids, and PID. While endometriosis and PCOS cannot be cured, there are effective treatments available that could help your menstrual cycle to balance itself out.