Yes, using Kmspico can potentially cause several issues. Since Kmspico is not an official Microsoft product, it may not be fully compatible with all versions of Windows or Office. This can lead to software instability or malfunctions. Additionally, because Kmspico is often distributed through unofficial channels, it can sometimes be bundled with malware, which might compromise your system’s security and performance. Finally, using such tools can result in legal consequences if you are found to be violating software licensing agreements.