Mescaline is the primary psychoactive alkaloid in a range of psychedelic cacti native to the Americas. In its natural state, mescaline has been used for thousands of years in Native American religious ceremonies. Some of the most popular mescaline containing cacti are: Peyote, San Pedro and Peruvian Torch. The most popular way to take mescaline is to weigh out your dose and pack it into capsules, then swallow on an empty stomach. You could also dissolve the powder in bitter fruit juice, such as grapefruit, to mask the taste. Mescaline effects are generally felt within 45-90 minutes of consumption,  peaking at two to four hours and lasting for up to eight. During this time, you are likely to see closed-eye visuals of colors and patterns, such as mosaics, arabesques, and spirals transforming into visions of more definite objects like architecture, animals, and humans. At the same time, ordinary objects in your surroundings may appear more interesting, beautiful, and amazingly mystical—qualities that define the mescaline experience. Your physical environment, as well as your own body, may distort in size and form. Some have reported the apparent loss of limbs, for instance, or the sense that hard objects like stones or walls have become soft and malleable to the touch. Other senses are also affected, sometimes to the point of synesthesia, whereby, sights may be “heard” and thoughts may be “smelled.” Beautiful perfumes and music, or voices speaking strange languages, have also been reported. For many, mescaline produces an experience of depersonalization or the dissolution of the ego; everything, including oneself, can therefore feel unified. Accompanying this may be clear and connected thought, self-realization, empathy, and euphoria. However, “bad trips” and dysphoric symptoms may be more common among people who don’t pay attention to set and setting and/or have histories of mental illness. References: • The Ultimate Guide to Mescaline by The Third Wave