We suggest to use common sense when deciding where to roll. The AMP MD Derma-Roller should not be used on cold sores, herpes, acne, open wounds, active acne, fungal infections, skin disorders such as active rosacea, seborrheic dermatitis, eczema, psoriasis, raised moles, warts, or any other skin inflammation, redness, irritation or infected skin. Do not use on dilated capillaries or sensitive skin or if on blood thinners. Avoid the AMP MD if you have a metal allergy. Do not use the AMP MD Derma-Roller near the eyes. Do not use within three days of any professional treatments such as peels or waxing. People who have a pre-existing skin condition should consult their medical professional before using the AMP MD System.