Yes, in almost every way! While at-home aligners may seem like a cheaper, more convenient option, they are not supervised by a professional (which is essential in more complex cases). Additionally, you might need attachments to help move your teeth, which can only be installed by a dentist.
Invisalign may cost a little more than at-home aligners, but it is most certainly worth it for the peace of mind that your treatment is going to plan.