Yes, it would be best if you clean the filters regularly. If you clean the filters frequently, it will improve the cooling and heating system of your AC unit.
Thereby it will improve the indoor air quality of the air conditioner.
By regular filter cleaning, it will ensure proper airflow, and also it will help to keep your home free from allergens, dust, and germs.
According to the type of the filter, you may also clean it weekly or monthly.