Several factors can affect an individual’s response to wine and their ability to gain weight when drinking it. These factors include: n Genetics: Some people may have a genetic predisposition that makes them less likely to gain weight when drinking alcohol. n Metabolism: Individuals with a faster metabolism may be able to process alcohol more quickly and efficiently, reducing the likelihood of weight gain. n Physical activity: Regular physical activity can help counteract the calories consumed from drinking wine and other alcoholic beverages. n Dietary habits: Individuals who consume a healthy, balanced diet with fewer high-calorie foods and beverages may be less likely to gain weight when drinking wine. n Drinking patterns: Consuming wine in moderation, rather than binge drinking or consuming large amounts of alcohol in one sitting, can reduce the likelihood of weight gain. n Type of wine: Some varieties, such as dry wines, may contain fewer calories than sweet or fortified wines. While some individuals may not gain weight when drinking wine, excessive alcohol consumption can still have adverse health consequences, including an increased risk of liver disease, certain cancers, and mental health issues.  Additionally, some individuals may be more susceptible to the harmful effects of alcohol than others, and it’s essential to be mindful of your alcohol consumption and make healthy choices.