A meta-analysis of 8 studies showed a benefit in improving subjective sleep quality parameters as measured by questionnaires. However, larger, randomized trials must further confirm these findings. Additionally, the long-term safety of using saffron for insomnia has yet to be explored.A meta-analysis of 8 studies showed a benefit in improving subjective sleep quality parameters as measured by questionnaires. However, larger, randomized trials must further confirm these findings. Additionally, the long-term safety of using saffron for insomnia has yet to be explored.