The main difference between a vape cartridge and a disposable vape is that a vape cartridge does not include a battery while a disposable vape features a battery built into the unit. On the one hand, disposable vapes offer less customizability, but on the other, they’re undeniably more convenient than a vape cartridge + battery combo. Weigh the pros and cons, and decide which option is best for your personal circumstances — maybe both.