The straight answer to a question pertaining the difference between a real diamond and an American diamond is that the latter ones are lab made. But hey! Diamonds are a woman’s best friend no matter what kind they are. Technically speaking, American Diamond is the cubic crystalline form of zirconium dioxide (ZrO2) while real diamonds are just a crystalline form of carbon atoms which is formed under a high temperature and pressure. However, it has been observed in multiple studies that both, American and real diamonds share almost similar kind of clarity besides being colourless and flawless in their appearance.