Bravecto and Frontline are popular dog flea and tick treatments, but they work differently and have different advantages. Bravecto contains the active ingredient fluralaner, which inhibits the nervous system of fleas and ticks, ultimately leading to their death. It provides long-lasting protection for up to 12 weeks with just one dose. On the other hand, Frontline contains the active ingredients fipronil and (S)-methoprene, which works by targeting the nervous system of fleas and ticks, as well as preventing the growth of flea eggs and larvae. Frontline must be applied monthly to provide continuous protection against fleas and ticks. In terms of effectiveness, both Bravecto and Frontline are highly effective at killing fleas and ticks. However, Bravecto may be more convenient for pet owners who do not want to administer medication every month. Additionally, Bravecto may be more effective against certain ticks, such as the lone star tick, which Frontline does not effectively kill. Ultimately, the choice between Bravecto and Frontline will depend on a pet owner's preferences and their dog's specific needs. It is best to consult a veterinarian to determine which treatment is most appropriate for a particular dog.