According to the American Cancer Society, nearly 50,000 men and women are diagnosed with pancreatic cancer in the United States annually. The average person has a one in 67 chance of developing the disease, but certain factors can increase the odds. For example, you're more likely to be diagnosed with it if you are older than age 45, male, or Black American, if you are overweight or obese, if you smoke, and if you have a family history of the condition.