The major sins in Islam are called the Al-Kaba'ir (the great sins). They include shirk (associating partners with Allah), murder, unlawful sexual relations (Zina), theft, making false accusations of unlawful sexual relations (Qadhf), drinking intoxicants, and Riba (usury or interest). All of these actions go against the principles of fairness, justice, and morality in Islam and are considered to have serious consequences in this life and the afterlife.