The results from CoolSculpting are permanent since the treatment actually kills the targeted fat cells, rendering those cells incapable of regenerating or growing back. However, since it is fat cells that are removed, if you were to gain a fair amount of weight, it is likely that the new fat cells would develop in those areas that had been previously treated simply because that may be where your body naturally stores fat. So, the results are permanent as long as you continue living a healthy lifestyle and are able to avoid putting that excess weight back on.