Yes, you can use a neck pillow in bed. You can use this pillow in many different ways. Either you can use it by sliding your neck onto the pillow. To do so, you can lie down in bed ad place your neck in or on the pillow. However, make sure you are not moving much while using a neck pillow. It is also important to make sure that your head, shoulders and back is touching the surface where you are lying on.   It is also important to check your full body alignment while using a neck pillow in bed. Whereas never use a neck pillow if you are a stomach sleeper. Doing so can cause pain in the lower back and neck.