We recommend using the removable cotton cover on the mattress topper to prevent spills directly on the latex. We recommend that you spot-clean the cover with a mild detergent & brush then place the cover in the sun because natural sunlight is excellent at completely disinfecting textiles. The cover is not machine washable because it is made with untreated cotton that is not pre-shrunk, so it may shrink in the wash.If a spill occurs on the latex material, gently spot clean with a damp cloth and rub gently.Avoid direct sunlight on an uncovered latex topper, this will cause the natural material to break down faster.