Yes, the stuffing material in plush toys is important for your dog's safety. Some stuffing materials, like small beads or certain types of foam, can be hazardous if ingested, potentially leading to intestinal blockage or choking. Opt for plush toys with safe, non-toxic stuffing or those made with minimal stuffing to reduce risks. Additionally, some toys are designed with a stuffing-free concept to offer the softness of plush toys without the danger of ingestion, making them a safer option for dogs who like to de-stuff their toys.