Endocrine disorders are a group of illnesses that affect the glands in the human body and cause hormonal imbalance. The endocrine system is a collection of glands that create and discharge hormones into circulation to keep the bodys functions and metabolism in check. These are life-long illnesses with a variety of causes that impair the health and quality of life of those affected. Diabetes, thyroid diseases, osteoporosis, Cushings disease, adrenal insufficiency, and polycystic ovarian syndrome are all common endocrine disorders in humans.