The proper dosage of Enbrel will vary between patients and is based on several factors. You should always follow your doctor’s instructions or the directions on the label. The information below refers to typical doses of Enbrel. If these doses are not consistent with your prescription, follow your prescription. The dosage patients are typically prescribed will be based on the condition it’s being used to treat, your age, the form of Enbrel you’re taking, and any other medical conditions you are affected by. Enbrel is available as a prefilled syringe, autoinjector, powder, and prefilled cartridge. The following are standard doses: Rheumatoid arthritis – 50 mg once weekly Psoriatic arthritis – Weekly 50mg doses Ankylosing spondylitis – 50 mg once weekly Plaque psoriasis – 50 mg twice weekly for three months, followed by 50 mg once weekly Polyarticular juvenile idiopathic arthritis – Dosage is determined based on weight