Rebound COVID-19 is when a person who has been treated for COVID-19 tests negative, then shortly after, gets symptoms again. Rebound symptoms typically occur within two to eight days of completing a treatment course. Rebound COVID-19 has also been reported in untreated patients and is likely a natural disease process. It is uncommon, happening in 1%-2% of patients. It is not the same as reinfection with the virus or resistance to treatment.
People with rebound COVID-19 should not be retreated for the virus. They should manage symptoms with over-the-counter medications, as advised by their doctor, return to isolation and wear a face mask. If symptoms progress or become more severe, they should consult with their doctor.