Disease-modifying antirheumatic drugs (DMARDs) are used to treat rheumatoid arthritis and other forms of autoimmune arthritis. DMARDs are started early in the disease and can achieve disease remission in roughly 50% of cases. Conventional DMARDs include: Methotrexate Azulfidine (sulfasalazine) Arava (leflunomide) Plaquenil (hydroxychloroquine)