Yes, Clenpiq, like other bowel preparation products, can cause electrolyte abnormalities, especially if patients become dehydrated. It is important to consume additional clear fluids as recommended to stay hydrated and maintain proper electrolyte balance. Patients with severely reduced renal function or renal failure should use caution when taking Clenpiq due to the risk of magnesium accumulation. Discuss any existing renal impairment or concomitant medications with a healthcare provider before using Clenpiq.