People with kidney disease, liver disease or Reye’s syndrome should not use glutamine. Many elderly people have reduced kidney function, and may need to reduce the dose of glutamine.Glutamine is different from glutamate (glutamic acid) monosodium glutamate and gluten. Glutamine will not cause symptoms (headaches, facial pressure, tingling or a burning sensation) associated with sensitivity to MSG. People who are gluten-sensitive can use glutamine without problems.