99% eradicated—but long, tough road remains Only 2 countries remaining w/ endemic polio (Afghanistan & Pakistan) Global efforts led by WHO & Rotary International Unvaccinated pops. threaten others, especially in neighboring countries that have achieved eradication Eradication hampered by physical geographies (e.g., mountains, isolation & remoteness) & cultural resistance (e.g., religious, social, political & general skepticism)