Yes, says Rountree: “There’s no question that you should take probiotics while on antibiotics.” While it may seem counterintuitive to ingest bacteria while taking a bacteria-killing agent, remember that probiotics are “friendly” microorganisms that benefit the gut environment as they pass through.
“Probiotics can be synergistic with antibiotics, especially in clearing out infection with H. pylori,” observes Ruscio. “You also get fewer adverse effects from antibiotics when they’re coadministered with probiotics.”
S. boulardii can be particularly useful. Because it’s a yeast and not a bacteria, it’s not affected by antibiotics. It can also help fend off the overgrowth of Candida albicans — a common side effect of antibiotic treatment. Lacto-Bifido blends can help reduce antibiotic-associated diarrhea as well, particularly if taken within a few hours of an antibiotic dose.