At first glance, Juvederm and Botox have many similarities. They are both injected, primarily into the face, and they both treat fine lines and wrinkles. However, they use different active ingredients and perform different duties. Juvederm is a dermal filler, a gel made from hyaluronic acid that fills lines in the face and smooths the appearance of wrinkles, while Botox uses a purified form of the Botulism toxin to cut off nerve signals to the muscles, relaxing the contractions and making the wrinkles less apparent. Each treatment is also used for different kinds of wrinkles. Juvederm is best for wrinkles that are obvious when your face is at rest, while Botox is best for active or dynamic wrinkles made when the muscle is used, such as when you smile or frown. The results of Juvederm can be seen right away and may last from nine months to two years for some people, while the results of Botox may take a few days and begin to fade after five to nine months. Each procedure is temporary and will require multiple treatments.