The average dosage is 155 units of Botox per injection. According to the American Migraine Foundation, the average treatment cost is $300 to $600.Botox injections can be costly with Original Medicare only, and Many Medicare beneficiaries enroll in a Medigap insurance plan or Medicare Advantage plan to help offset the costs. We can assist you with finding the coverage that fits your needs. Our licensed insurance agents have access to all the programs in your area.Then we educate and assist you with your Medicare questions and needs. Give us a call to fill out our online request form for assistance with your Medicare options.