• The best indication that your calzone has gone bad is the smell. If your calzone smells off, then it needs to be tossed. • If the calzone has dried out and is hard, it is past its best and better to be thrown out. • If you notice mold or any other kind of spoilage or growth on the calzone, then it has spoiled. • If your calzone feels oily or slimy then it has gone bad. • Finally, taste your calzone and if it tastes sour or off then it has spoiled. Do not consume spoiled calzones as they can give you food poisoning.