Yes, ZiZU can accommodate prescription lenses in two different ways: 1. Optical inserts for XZ1, OPZ and Z-Shield The clip (purchased from ZiZU and filled by your optometrist) snaps to the inside of the nose piece. This allows the wearer to benefit from ZiZU Optics tinted lens technology. The clip can be removed from the frame to use the sunglasses by themselves.2. Prescription insert for NZ2 The insert (purchased from ZiZU; filled and tinted by your optometrist) easily locks into the frame replacing the existing tinted lens. The frame and prescription insert may be purchased either with or without the purchase of a ZiZU tinted lens.