Experts consider THCO a "semi-synthetic" cannabinoid. The cannabinoid does come from the hemp plant, and it couldn't be created without it; however, curators have to use a chemical additive to get the cannabinoid to where it is. That addition of acetic anhydride is what makes the cannabinoid partly synthetic. So, no, you're not going to find THCO naturally within the cannabis plant. But, the cannabinoid does come directly from cannabis plant compounds.