Dr. Tennant’s Lugol’s Iodine Plus capsules are able to be taken without Restore, as they do contain the appropriate levels of coenzymes to help with proper iodine metabolization. Dr. Tennant however does recommend that Iodine, Raw Materials, Digestive Enzymes and Restore, as well as Neo40 (if over the age of 40) should be taken as a complete system for optimal cellular regeneration.