If the stocking is latex free, it is perfectly safe to use lotions or creams. In fact, it is especially important for people with lymphedema or venous insufficiency since daily skin care and moisturizer is so important. Applying lotion at night will make donning the stockings easier. If the stocking contains latex (some of the Jobst SupportWear), do not use lotions or creams. Heat, ultraviolet light, copper containing products, hydrocarbons and all petrolatum containing creams and ointments affect garments that contain natural rubber latex yarns.