There are no particular drugs made just to drain ear fluid. However, nasal corticosteroids like fluticasone or decongestant drugs like pseudoephedrine can assist in lessening nasal congestion, which may inadvertently relieve ear pressure and aid in ear fluid drainage. If an ear infection is present, doctors may also advise antibiotics since they can speed up the healing process and lessen fluid buildup. A skilled healthcare expert should make that decision, however, following a correct diagnosis and evaluation of the underlying source of the ear fluid.