No, queen mattresses should only be used with queen size frames or foundations. Every non-adjustable bed frame is designed to accommodate mattresses of a certain size. Using a frame that’s too small for your queen size means the mattress won’t fit within the frame’s edges. This can make your mattress sink in the middle and feel very uncomfortable, and may also cause damage to both the mattress and the frame. Some bed frames have adjustable width and length settings, so these models could potentially accommodate both a full and queen size mattress. However, these are fairly rare. The best rule of thumb is to buy a bed frame that corresponds to your mattress size.