To open an Osprey backpack, first locate the two buckles on the front of the bag. These are usually located at the top and bottom of the bag. Once you've found them, undo both buckles. Next, find the zipper that runs along the side of the bag. This is typically located on the left side of the bag. Undo this zipper, and then pull back the flap of fabric that covers it. Now you should be able to see into the main compartment of the backpack. If there are any pockets inside, you can access them by opening up the zippers that run along their edges.