Commercially-grown pawpaws may contain pesticides or other unwanted chemicals, but home-grown fruits are generally safe to eat. Some people have allergic reactions to the fruit, so proceed with caution if you have a history with food allergies. Never consume the skin or seeds, as these contain low levels of toxins that can harm humans. Consume the fruits in moderation and you should not experience any issues. Their flavor is custard-like and tropical, often being compared to mangos, pineapples, and bananas.