Yes, to maintain the beauty of your enamel jewelry, it is recommended to avoid exposure to harsh chemicals, such as perfume, lotions, or cleaning agents, as they can damage the enamel finish. It is also advisable to store the jewelry in a separate pouch or compartment to prevent scratching from other items. Cleaning the enamel pendant necklace with a soft, damp cloth and avoiding excessive moisture will help preserve its vibrant colors and shine.