KMSpico is designed to activate various versions of Windows and Microsoft Office, including Windows 10, Windows 8, and Office 2016. However, its effectiveness may vary depending on the specific version of the software and the updates applied by Microsoft. It’s recommended to check the compatibility of KMSpico with your specific version before attempting activation. Additionally, keep in mind that using KMSpico on newer versions may not be advisable as they may have stronger activation checks.