Khufu uses low-pass whole genome sequencing to input SNPs and traits. The average sequencing coverage is <3x per sample. With this whole genome sequencing coverage, Khufu is able to look for not only pre-identified markers of interest but also call out additional SNPs across the genome. When using an array, you are limited to the panel that has been previously developed, which may or may not have been customized to your specific population, and will only ever call the pre-determined 3,000-50,000 markers. Meanwhile, you can expect 100,000 and up to 1,000,000+ markers with Khufu.