According to my blackjack appendix 9H the expected return of standing is -0.476476 and of hitting is -0.408624, assuming the 16 is composed of a 10 and 6. So my hitting you will save 6.79 cents for each dollar bet. This is not even a marginal play. There is no sound bite answer to explain why you should hit. These expected values consider all the numerous ways the hand can play out. The best play for a billion hands is the best play for one hand. If you want to deviate from the basic strategy here are some borderline plays: 12 against 3, 12 against 4, 13 against 2, 16 against 10. Deviating on these hands will cost you much less.