Yes, they can. Although the improvements can last many years, they are usually not permanent and may have to be repeated periodically. Dermabrasion and medium-depth chemical peels have both been used for many years to improve the appearance of superficial wrinkling, to eliminate sun-induced pigmentation and keratoses and to improve the overall surface texture of the skin. In the past decade, laser resurfacing has grown popular because it may be easier to control and therefore produces a more predictable outcome. Laser resurfacing, however, is usually more expensive and frequently involves longer healing times, possibly requiring the patient to remain at home until healing is complete. The newest laser resurfacing procedures are fractionated. These include ablative (which disrupts the epidermis) and non-ablative (which sends heat into the dermis and leaves the epidermis intact). These procedures require multiple treatments, but have reduced healing times. All of these procedures, if done correctly, are relatively safe, although localized scarring and pigment alterations can occur in a small percentage of patients. Botox or Dysport, (botulism toxin type A) helps smooth moderate to severe facial frown lines for up to six months. Small doses of a purified, sterile form of the toxin are injected into certain facial muscles, which temporarily paralyzes and weakens them. When the muscles can't contract normally, frown lines disappear. According to the FDA, Botox treatments should not be injected more frequently than once every three months, and the lowest effective dose should be used. Side effects may include nausea, rash, localized muscle weakness, flu-like symptoms and redness at the injection site. These side effects are usually temporary. If they persist, call your doctor.