A. Men who have or have had prostate, testicular or breast cancer should not take hormone replacement therapy. Other contraindications may include but not limited to: swelling, shortness of breath, sleep apnea, heart disease, kidney disease, liver disease or cirrhosis, alcoholism, untreated asthma, untreated copd or emphysema, untreated diabetes, adrenal gland disorder, prostate enlargement, untreated thyroid disorder, cancer or tumor of pituitary gland, lung, liver, hypothalamus, melanoma, current chemo or radiation therapy, surgery within the last 6 weeks, competitor in any type of sports including but not limited to professional, high school or college sports.