MiGuard formulation is based on the most recent and advanced scientific evidence and research conducted by the American Academy of Neurology and the American Headache Society. MiGuard is distinctly different as it contains Alpha-Lipoic Acid which is naturally occurring and a very powerful antioxidant. There is strong evidence that 90% of individuals with high frequency migraine headaches have significantly lower levels of Alpha-Lipoic Acid in their serum and therefore, supplementation with MiGuard may replenish this very essential compound. Also, MiGuard does not contain Butterbur which is an herbal supplement found in many other over the counter headache supplements. Prolonged use of Butterbur has been associated with severe liver injury and hepatic failure.