The following are some of the common conditions in which atrophy of human hippocampus has been reported: Alzheimer's disease[5,6,8,66] Atrophy of hippocampal region in brains is one of the most consistent features of AD. ... Epilepsy[3,6,8] ... Hypertension[3,6,8] ... Cushing's Disease[3,6] ... Miscellaneous Causes[3,6,8]