These genes are helpful in controlling the development of the body. These genes have been studied in the drosophila. Homeodomain proteins help in controlling the genes. Homebox or the conserved sequence help in the formation of these genes. This homeobox is present in the coding region of the homeotic genes. When mutation takes place in these homeotic genes, then conversion of one body part into another takes place. These are seen in the transcription of eukaryotes.