The use of mannitol are given below:Mannitol is used to promote diuresis for renal failure- Mannitol can promote diuresis for acute renal failure to prevent or treat the oliguric phase before irreversible damage.Mannitol is used for increased intracranial pressure- Mannitol constitutes a solute in the plasma, this increases the tonicity of the plasma. Since mannitol cannot cross the intact blood-brain barrier, therefore, it is responsible for increased intracranial pressure.Mannitol is used for the excretion of toxic material- The mannitol is poorly reabsorbed once it gets excreted from the body, it draws extra water with it into the renal collecting ducts.Mannitol is a sweetener for diabetic food products- Mannitol when ingested orally passes through the intestine and excreted in the feces as the small intestine absorbs it poorly. So, it does not affect blood sugar.Mannitol is used to prevent intradialytic hypotension- It raises the serum osmolality. Hence, prevent hypotension.