That'll largely depend on the turbo kit and kind of custom work you're willing to do. If you're using a typical setup that comes with new/custom exhaust manifolds where the turbos are mounted with hot side tubing going into a front-mount intercooler and cold side tubing going into the throttle body/intake manifold, then you shouldn't have too many issues. You'd just need cold side tuning that reaches to the Boss Manifold. The intake included in this kit, would likely be pretty worthless to you, however. Your turbos are going to need some sort of customized intake system, and the intake included in this kit will not work with turbos.