Yes, both dogs and cats can take azithromycin, but it should only be used under the guidance and prescription of a veterinarian. Azithromycin is a broad-spectrum antibiotic that is effective against a variety of bacterial infections in both dogs and cats. Azithromycin is commonly used to treat respiratory tract infections, skin and soft tissue infections, and certain gastrointestinal infections in dogs and cats. It is also sometimes used as a preventative treatment for certain respiratory infections in specific situations. The dosage and duration of treatment with azithromycin will vary depending on the specific condition being treated and the individual animal's characteristics.