John BennettA graphical display of the results of a multi-gene panel is an effective means for viewing and understanding the number, types, and clustering of detected genomic alterations. One potential method for creating this display in SAS involves use of the HIGHLOWPLOT statement. The HIGHLOWPLOT statement can be used to create a color-coded grid to display gene panel results for a patient cohort. When this technique is used in combination with other graphical statements, attributes, and definitions, it can create a data-rich display that is both eye-catching and useful as a multi-dimensional summary of gene panel results.This paper contains a stepwise set of instructions for using the HIGHLOWPLOT statement to create a grid, using as an example the results of a next-generation sequencing (NGS) gene panel assay for patients with non-small cell lung cancer. The steps involve use of the SAS Graph Template Language (GTL) and the SGRENDER procedure using SAS 9.4. The HIGHLOWPLOT statement does the heavy lifting in this example, but additional techniques are used to increase the utility of the display, such as a layout lattice, attribute maps, additional scatterplots, and discrete legends.