Yes, you can sew plastic on a sewing machine. In fact, many types of plastics can be sewn on a sewing machine, as long as you use the correct needle and thread.
For example, PVC and polyester are two types of plastics that can be easily sewn on a sewing machine. However, before you start sewing plastic on your machine, it's important to test out a few small stitches on a scrap piece of fabric first. This will help you ensure that your needle and thread are compatible with the type of plastic you're working with.
If you're looking to sew thick or heavyweight plastics (such as vinyl or leather), you may need to invest in a heavy-duty sewing machine. These machines are designed to handle thicker materials, and they usually have more powerful motors than regular sewing machines.