While fibroids are not typically considered life-threatening, they can cause many adverse health effects. Because they can distort the uterine cavity, fibroids can contribute to fertility issues, affecting a woman’s ability to conceive. Approximately five to ten percent of infertile women have fibroids. Fibroids that develop on the inside of the uterus can make alterations to the uterine lining and negatively influence embryo implantation or development, potentially increasing the risk of miscarriage. During pregnancy, fibroids are also associated with placental abruption, preterm labor, and babies who develop at a rate that is smaller than normal for their gestational age. When the uterine cavity is distorted by large fibroids, it may also increase the risk for cesarean delivery, breech birth, or abnormal labor.