Lip filler is a non-surgical treatment that does not involve making any cuts or use of sutures. It is an injectable treatment during which you may feel mild discomfort. Most patients feel like a tiny scratch as the filler injection is administered into the lips and a tingling sensation after fillers are emptied into the lips. Advanced lip filler injections come with a numbing agent and therefore patients will experience no or minimal pain. If you are feeling anxious, you can get a numbing cream applied over the lips beforehand to completely undergo a pain-free treatment.