The etiology of Alzheimer’s disease for the most part is genetic in nature. It is thought to arise from a genetic mutation. Other causes include certain environmental factors, toxins and lifestyle. The cholinergic neurons of the basal forebrain are primarily affected by AD. Microscopic examination reveals the deposition of intracellular and extracellular β- amyloid or Abeta (Aβ) protein, intracellular formation of neurofibrillary tangles and neuronal loss.