Because fluticasone nasal sprays work chiefly within your nose, very little of the drug travels elsewhere in your body. However, like all medicines, fluticasone can sometimes have side effects. It is possible to have an allergic reaction to the product, in which case you may experience: Sudden swelling of the face or tongue A rash Wheezing or feeling faint The development of eye conditions such as cataracts and glaucoma has been reported with use of fluticasone nasal sprays. You should have a yearly eye exam to check for these conditions, but see a professional sooner if you experience any problems with your eyes, such as cloudy or reduced vision. The most common side effects reported with use of fluticasone nasal sprays include: Headache Nausea and vomiting Sore throat Nose bleeds Trouble breathing Cough Nose burning or itching These are not all the possible side effects with fluticasone nasal sprays. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In addition, some children who use fluticasone may have a slower growth rate while using the product. Speak to your child’s doctor if you are concerned, or if your child is between 4 and 11 years of age and needs to use fluticasone nasal sprays for longer than 2 months a year.