Jesduvroq and Aranesp are both used to raise hemoglobin levels and to treat anemia associated with chronic kidney disease (CKD). However, they differ in their active ingredients, indications, ways of working in the body, routes, frequency of administration, side effect profiles, and warnings. Neither Jesduvroq nor Aranesp has been proven to improve quality of life, tiredness (fatigue), or well-being.