Product TypeFee payable where the licensing authority carries out a full assessmentFee payable where the licensing authority carries out a paper-based assessment Plasma pools which require three or fewer tests£198£99 Plasma pools which require four or five tests£237£99 Plasma pools which require six or more tests£253£99 Band A – single component product, other than Botulinum toxin. requiring five or fewer in vitro tests£1,826£367 Band B – Factor VIII, Factor VIX or intravenous Immunoglobin£2,101£367 Band C – Multi-component product, or Botulinum toxin, requiring five or fewer in vitro tests£2,574£992 Band D – product requiring six to nine in vitro tests£4,059£992 Band E – product requiring (a) ten or more in vitro tests, or (b) one or more in vivo tests£7,051£1,849 Band F – one or more tests that must be carried out under containment measures applicable to hazard Group 3 or 4 biological agents under Control of Substances Hazardous to Health Regulations 2002 (123) or requires use of human tissues or cells as part of testing£11,385£1,849