Using both Transdermal and Oral Magnesium as part of a daily regime is a great way to treat and prevent Magnesium deficiency. Some people find that they get the best relief from their symptoms when they double-up on Magnesium. There is no reason to avoid using both. Your body regulates the amount of Magnesium it absorbs through the skin, so there’s no risk of applying too much topically. If you experience a gentle laxative effect from Oral Magnesium Supplementation, simply use less of the powder and more of the Transdermal Magnesium.