Milk thistle supplements may indirectly benefit your skin by supporting liver health. A well-functioning liver efficiently removes toxins from the body, which can result in clearer, healthier skin. Most recently, the cast of Barbie have touted the benefits of milk thistle tea for glowing skin. However, more research is needed to confirm these effects.However, check with your doctor before starting a milk thistle supplement, as this herb may negatively interact with certain medications.