Yes. Both Adderall and methamphetamine have a significant potential to induce physical dependence in people who use the drugs regularly and in significant amounts. Physical dependence consists of the development of tolerance to the substance followed by later development of a withdrawal syndrome.The withdrawal syndrome for stimulant drugs is similar across nearly every stimulant of abuse. The American Psychiatric Association lists the formal diagnostic symptoms for stimulant withdrawal as being applied to all stimulants of abuse.Although methamphetamine and Adderall are very similar substances, they are not the same drug.Many people view methamphetamine as a far more dangerous substance than Adderall. When they think of methamphetamine, they often think of crystal meth, whereas most people know that Adderall is a prescription medication. Both are potentially dangerous drugs of abuse.Many sources, including the book Methamphetamine: Its History, Pharmacology, and Treatment, report the results of research studies where chronic abusers of methamphetamine were given Adderall, and they were not able to tell the difference between the effects of Adderall and the effects of methamphetamine. Thus, even though the drugs are slightly different chemically, their overall effects are very similar.Methamphetamine refers to professionally manufactured medication. Crystal meth is the illicitly produced street version.Although the chemical substances in methamphetamine and Adderall are similar, the process used to make crystal meth (the street version of methamphetamine) requires potentially dangerous and toxic substances, such as drain cleaner, ammonia, phosphorus, and other chemicals.Abuse of crystal meth can lead to serious damage to organ systems in the body because of these potentially dangerous additives. Chronic abusers of crystal meth often suffer numerous neurological, physical, and emotional problems that may not be reversible.Whether you’ve been using these drugs as prescribed by your doctor or abusing them, you’re going to experience a form of stimulant withdrawal. How long you’ve been using the drugs and the manner in which you use them will indicate the severity of your symptoms. Stimulant withdrawal results from your body relying on drugs to regulate cognitive focus and function. Over time, even someone who uses the drugs to study can develop physical dependence. If someone is addicted to Adderall or meth and tries to stop, they’ll battle withdrawal because their body is learning how to function without the chemicals. Withdrawal symptoms can be both physically and psychologically taxing and can range from moderate to severe. The psychological withdrawal from stimulants is especially taxing, leading to relapse and the individual becoming suicidal or violent. For this reason, stimulant users must seek professional medical help when stopping these drugs. A stimulant use disorder as a result of abusing Adderall or methamphetamine can be a life-threatening condition if it is not treated by professionals. Such abuse can result in severe physical and mental problems in the long run.Treatment for abuse or methamphetamine abuse should consist of a well-rounded treatment program that is run by addiction treatment professionals. The vast majority of people who have developed substance use disorders are unable to change their behavior without professional help.