Prices vary depending on the time of the year and how much you purchase your tickets in advance. But usually, we can say that a round-trip ticket from Istanbul to Cairo will cost around 200 Euros up to 400 Euros depending on the season. EgyptAir, flying in and out of Cairo can be much cheaper, as it is one of the most famous low-cost airlines in Europe. Flying from Madrid round-trip usually costs around 350 Euros. EgyptAir through Berlin has tickets available for around 390 Euros return.