Grado in-ear headphones provide better noise isolation than other headphones. For example, noise-canceling headphones can do excellent in isolating low-frequency noise such as airplane engines but not so well for higher frequency noises.  Noise-isolating headphones, however, have one oddity of creating sound oddities. Bose headphones do not focus on sound quality, so Grado delivers better sound quality than Grado in-ear headphones. However, if your priority is noise isolation, Bose noise-isolating headphones are better.