For both plaque psoriasis and psoriatic arthritis, you’ll receive your first two starter doses of Skyrizi four weeks apart, then you’ll have an injection every 12 weeks thereafter (4 maintenance doses per year). For Crohn's disease, you'll receive 3 starter doses given into a vein 4 weeks apart (Week 0, 4 and 8) at a healthcare facility, then a subcutaneous (under the skin) injection given at Week 12, followed by an injection using a prefilled cartridge with an on-body injector every 8 weeks thereafter (6 maintenance doses per year).