The rate at which your dermal filler will dissolve is dependent on your age, metabolism, the mobility of the treated area, and how well you adhere to aftercare instructions following your procedure. Those with faster metabolisms will typically experience shorter results because their bodies will break down the filler faster than those with slower metabolisms. In addition, the more mobile the treated area, the faster the filler will dissolve. As the lips are one of the most active areas on the face, used for talking, eating, kissing, breathing, and facial expressions, filler tends to dissolve faster in this area.