Proper compression glove fit is vital to getting the right amount of compression and pain relief from edema or arthritis. For an accurate glove size, measure your palm circumference at its thickest part. For example, ScripHessco offers Isotoner Gentle Compression Gloves in small (5 ½” to 6 ½” ), medium (6 ½” to 7 ½“), large (7 ½” to 8 ½ “), and extra small (4 ½“ to 5 ½”).