Some forms of contraception are affected by Topiramate use while others are not. The coil and contraceptive injection are safe to use while on Topiramate. A small number of women have been known to experience contraceptive failure while on the pill (progestogen and combined). If taking the emergency contraceptive, please make sure to let the pharmacist or doctor know you’re taking Topiramate. The pharmacist or doctor might need to prescribe an increased dose.