To effectively monetize their online presence from the very beginning, entrepreneurs can employ several strategies. Firstly, they should create and offer a product or service to sell to their audience right from the start, even if it is at a low price point. This helps in generating revenue early on and establishes a monetization model. Additionally, entrepreneurs can leverage affiliate marketing, sponsored content, and advertising to generate income. Building an email list and utilizing it for targeted marketing campaigns can also be a successful strategy. Moreover, offering premium content or services for a subscription fee can create a steady stream of revenue. Overall, the key is to start monetizing early and continuously iterate on the monetization strategies based on audience feedback and market trends.