CBD and DMSO can be mixed, but we wouldn't recommend you mixing any ole CBD oil with DMSO. You see, there's a certain refinement process needed and it takes a standard manufacturing process to mix the two together in order to get the preferred results. Please note, standard CBD Oils are for oral consumption while DMSO is a topical product. When you mix the DMSO and CBD oil using standard methods, then it results in the quality CBD serums and creams that you're accustomed to!