Botox and Xeomin are neurotoxins that relax muscles and movement under the skin. Botox Cosmetic was first introduced in the United States in 2002, while Xeomin hit US markets almost 10 years later in 2011. While both toxins are classified within the same family of botulinum toxin A, onabotulinumtoxinA Botox, and incobotulinumtoxinA Xeomin, how they are formulated is what truly sets them apart from one another. Xeomin lacks additives and accessory proteins, so patients are less likely to develop antibodies that prevent the treatment from working as intended, reducing efficacy. Xeomin has been dubbed the naked or natural toxin because of its pure formulation. At the same time, Botox contains additives and accessory proteins, reducing effectiveness and increasing the possibility of an allergic reaction. However, the accessory proteins act as a buffer, protecting the primary protein molecule required to inhibit muscle movement, while the body naturally metabolizes the injectable product over time. On average, the onset of both toxins takes between 4 and 14 days, while the duration for both products is approximately 3 and 4 months. Botox has more FDA-approved treatable conditions, given its clinical evidence, market history, and dominance. And while both injectables have distinctive advantages and disadvantages, the question isn't whether one is better than the other. Instead, what's most important is the ability to maximize outcomes for every patient using each product. At DrSkin Med Spa, we pride ourselves on choosing the best injectable product for each patient by accounting for all vitally important factors: the skill, training, and experience of the injector, patient concerns and complaints, unique aesthetic goals, and past experience with each product and the treatment itself. We've seen amazing results using Botox and Xeomin, and in some cases, a combination of the two. If you're considering Botox Cosmetic or Xeomin treatment, please contact our medical team today at (480) 904-3311 and book a complimentary consultation with our doctors to see how we can help you look and feel your best!