It is not recommended to take Priligy at the same time as erectile dysfunction medications (including PDE5 inhibitors such as sildenafil), as ED medication can cause an adverse event such as low blood pressure. Patients with cardiovascular disease should use all erectile dysfunction drugs (such as a PDE5 inhibitor) with caution. You should always consult your doctor, healthcare professional or pharmacist prior to starting Priligy (Dapoxetine), whether or not you suffer from any chronic conditions, to ensure that it is the safest and most suitable premature ejaculation (PE) treatment to suit you.