No. Absolutely not and never ask that question to a Cajun! Ha! Only make gumbo when you have the time. Gumbo needs time and patience to really build up the flavors. With each step, you are slowly deepening and creating a rich and unique taste. Gumbo cannot be rushed and I do not recommend making this in a slow cooker or Instant Pot. I love to use those appliances too but you just cannot get the same level of flavors. I've tried so you don't have to!