Betting on the big favorites for their Moneyline is a big no-no since you will risk a lot of money if you want to receive at least a decent return. The risk of the favorite losing is simply not worth the bet. In the end, this is still sports betting we are talking about and crazy plays and games do happen! If you want to incorporate Moneyline bets into your betting slip maybe combine two or three favorites into a parlay but don’t make this your main bet type. Spread betting is not a good idea either if you are getting lines of -15 or larger. On average favorites just do not win by such big numbers consistently, maybe except for the Patriots… Even then, there are more profitable bets to be placed usually