The exact cost of amniotic membrane grafting varies based on the type you’re seeking, as well as where you live. It may be covered by private and government-based health insurance programs, but it’s important to check with a healthcare professional in advance. Individual device costs may range between $300–$900 each. But according to a cost effectiveness study published in 2020, the total average cryopreserved amniotic membrane procedure for dry eye was $10,300. The analysis also found that, when compared with topical immunosuppressants in a 1-year timeframe, amniotic membrane grafting was less expensive despite the higher initial price tag.