Cefpodoxime proxetil is an antibiotic used for treating a wide variety of bacterial infections. When cefpodoxime is taken with an anti-allergic tablet-like Lecope absorption of antibiotic is decreased. Lecope being an H2 blocker decreases the number of antibiotic molecules that enter your bloodstream and the effect is reduced. Hence lecope and cefpodoxime proxetil cannot be taken together