Most of the time, the answer is yes. There are certain corneal diseases such keratoconus, pellucid marginal degeneration, and epithelial basement membrane dystrophy, among others, that can cause irregular astigmatism. In these cases, LASIK may not be the best option, however, the good news is there are other procedures available to address these particular cases. A highly skilled eye surgeon like Dr. Waite, will be able to discuss with you the best options for your unique situation should you have an irregular astigmatism.