Game Theory Optimal (GTO) poker refers to a strategy that focuses on making unexploitable decisions based on game theory. This approach seeks to create a balanced strategy that cannot be countered, even by skilled opponents. In contrast, exploitative poker focuses on identifying and taking advantage of an opponent's weaknesses, deviating from GTO play when a profitable opportunity arises. While GTO play might not maximize winnings against weaker players, it protects against exploitation from strong players.