The short answer is yes, but gaming on a mesh can lead to some issues for competitive gamers. For gamers, latency, also known as ping, is the measure of time it takes your PC or console to communicate with a game server. High ping can lead to gaps between input and action onscreen called lag and an unstable connection can lead to intermittent spikes in ping known as lag spikes. While modern mesh routers are very efficient and rarely add more than a couple of milliseconds to your ping, any extra is a disadvantage in a competitive game.
For the best results, you can't beat a good Ethernet cable. For most gamers, however, something like the ROG Rapture GT6 should have more than enough performance to keep your games running smoothly. Wi-Fi can still be disrupted but with modern Wi-Fi technology, we've hit a point of diminishing returns for all but the most competitive gamers.