Microsoft 365 Business Premium was designed for small to medium-sized businesses with low to medium IT complexity requirements. Customers can purchase up to 300 Microsoft 365 Business Premium licenses for their organization. Customers can mix and match cloud subscriptions. As a result, depending on their IT requirements, customers might add another subscription, such as Microsoft Defender for Endpoint, Microsoft Defender for Business, or another Microsoft 365 Enterprise subscription to the same account.
If you are considering using multiple subscription types, consider working with a trusted IT advisor to determine how best to manage and secure the various subscriptions. Microsoft 365 Business Premium and Microsoft 365 Enterprise use different capabilities to secure and manage applications and data.