If you are considering how to store cantaloupe after picking them, then the best option depends on how soon you want to start eating it. After a cantaloupe has been picked from the vine it can be stored whole and uncut for around five to seven days at room temperature. Once the cantaloupe has been cut, it has a lifespan of three to four days in the refrigerator. It can also be cut and stored in the freezer for 10-12 months.