Treatment for high PSA levels depends on the underlying cause. If elevated PSA is due to benign conditions like prostate enlargement, your doctor might recommend lifestyle changes, medications, or procedures to manage the condition. If the high PSA indicates prostate cancer, further diagnostic tests, such as a biopsy, may be performed to confirm the diagnosis. Your doctor will finalize the treatment options for prostate cancer, which may include surgery, radiation therapy, hormone therapy, or active surveillance tailored to the specific stage and characteristics of the cancer.