Patients who have had systemic reactions to stings by vespids (honey bee, wasp, hornet, yellow jacket) or ants are at risk for allergic reactions that may be life threatening. Systemic reactions are those that cause low blood pressure, shortness of breath, gastrointestinal symptoms or swelling or rash distant from the site of the sting. Individuals who have experienced such reactions should carry injectable adrenaline that comes in pre-loaded syringes under the names Ana-Kit or Epi-Pen. These preparations are available by prescription only but can be life saving and should be carried by all patients with a history of systemic responses to these insects. It is especially important to carry one of these preparations if one is going to be participating in activities in remote areas. Antihistamines can be helpful but are not adequate for a life-threatening situation.