The Amplatzer device is a group of devices which is used to close abnormal channel which can include varied congenital or acquired conditions like ASD, VSD, PDA. The data available till now shows that it is very safe to close these defects with this device and it is approved now by the FDA in US for use in humans. The cost depends on the defect treated and varies from 50,000 (for PDA) to Rs 100000 (for ASD, VSD).