A drug known as pegylated interferon-alpha may be prescribed to help your immune system control the hepatitis D virus. Prescription or over-the-counter medications may be recommended to help manage the symptoms of hepatitis D such as pain, nausea, and vomiting. Avoiding ingredients that are tough for the liver to process—like Tylenol (acetaminophen) and nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin—is important.