Serum delivered frozen to a processing facility is thawed and tested for the presence of bacteria, virus, endotoxin and for hemoglobin content. The best quality serum is then filtered through a sequence of membrane filters, terminating with a 0.1 micron pore filtration under aseptic conditions. After filtration, aseptic conditions are maintained as serum is dispensed into sterile bottles, quickly frozen to -20 °C and quarantined until all lots have met or exceeded quality control standards. A certificate of analysis for each lot is available upon request.