These high protein smoothies can contain anything from 250 calories to 500! The higher calorie ones are a great option for breakfast, the lower calorie ones make a good drink to up your energy levels and give you a nice boost of protein between meals. However, high-protein smoothie recipes can massively vary in calorie content. Don't aim for low calorie content, because it's not realistic (or desirable) to get enough protein with very few calories.