The type of M protein immunoglobulins in your blood determines the type of MGUS you have:
* IgM MGUS: Up to 15% of people with MGUS have IgM immunoglobulins in their blood.
* Non-IgM MGUS: Most people have one of the other immunoglobulins: IgG, IgA, IgD, or IgE.
* Light-chain MGUS: M proteins typically have a light chain and a heavy chain. In light-chain MGUS, they only have a light chain.
Non-IgM MGUS and light-chain MGUS have a higher risk of progressing to multiple myeloma.