When you face QuickBooks error 6010 100 due to junk accumulation in the system, undertake the following solutions: 1. Use the Disk Cleanup utility. 2. Delete the cache, temporary files, and cookies from Internet Explorer. 3. Use Quick Fix My program and the clean install utility from the QuickBooks Tool Hub to fix performance issues and installation errors, respectively. 4. Undertake the System File Checker scan to fix the system files and eliminate the junk files. 5. You can also repair the QuickBooks application from the Control Panel to resolve the errors.