You are able to crush the tablets and mix them into water, but the herbs are very bitter. It is not a taste that you could disguise in a smoothie! Our advice if you cannot swallow them, is to crush them, add a little warm water and mix until dissolved into a liquid and quickly drink it! Dissolving the tablets do not change the efficacy of Zilch Acne Formula, and is completely safe. Zilch Acne Formula in its powder form is how it is dispensed at Dr. Vivian's clinic