Yes, it is possible to reconfigure your prebuilt PC. It, however, depends on your prebuilt PC and the manufacturer's specification choice when building the machine. However, there are some challenges that you may experience during this process. We have put together some of the issues that may arise and tips on how you may handle them. Insufficient power supply -  This may cause crashes and affect your system stability. This is a common occurrence, especially when you are upgrading your GPU. Your best option when facing this issue is to replace the power supply with a higher-end setup like the ATX or HTPC. Lack of M2  or NVMe ports - This makes it hard to upgrade your storage. If your existing slots are PCle, you can upgrade storage using a PCle SSD. CPU bottlenecks - This limits tasks such as heavy-duty rendering. You must use high-end CPUs with great single-core performance to avoid these issues.