Prior to first use (until expiration date): Ozempic should be refrigerated at 36°F to 46°F (2°C to 8°C). After first use (up to 56 days): Ozempic should be stored at room temperature 59°F to 86°F (15°C to 30°C) or refrigerated at 36°F to 46°F (2°C to 8°C). Do not store in the freezer or directly adjacent to the refrigerator cooling element. Do not freeze Ozempic and do not use Ozempic if it has been frozen. Keep the pen cap on when not in use. Ozempic should be protected from excessive heat and sunlight.