Yes you can drill holes in laminate flooring. If you choose an internal bifold door system with a bottom track such as those in the Roomfold Deluxe range, to install the doors you will need to cut your laminate flooring to sink the track that holds the bottom of the door panels. This is needed to keep your doors stable. Likewise, you'll need to install drop bolts that allow you to secure the door. If you use a sharp, strong drillbit it should not be hard to get a drill through laminate flooring - just take the job slow and steady to avoid splitting the laminate.