If you’ve looked into getting Botox, you’ve probably heard of the “four-hour rule.” The rule entails a few things, notably not rubbing or massaging your face. You should also avoid lying face down, and refrain from exercising at all, including light exercises like jogging. These preventative measures ensure the best Botox results in the four hours after your most recent injection. After four hours, you can start light exercises, but no strenuous exercises for a full 24 hours after Botox.