Yes! You can make this recipe for breaded butterflied shrimp in an air fryer. After the shrimp is coated in the breadcrumb mixture, preheat an air fryer to 400 degrees F (200 degrees C). Spray the tops with nonstick cooking spray and cook for 2-3 minutes. Using tongs, flip the shrimp over and spray the tops with nonstick cooking spray. Cook for 4 minutes more or until desired crispness. Serve immediately with your favorite sauce or lemon wedges. Enjoy your air fryer butterflied shrimp!