While hypoallergenic fabrics are meant for sensitive children and toddlers, they sometimes have the adverse effect. To gauge if hypoallergenic materials are right for your children, see how they handle small quantities of hypoallergenic fabric. You can give them a small swatch of hypoallergenic fabric and see if they have any adverse reaction. If no spots or irritation occurs, then you are good to go. If you do notice red spots or irritation, then it’s probably best to not purchase hypoallergenic products.