Yes. QuietComfort 35 wireless headphones II have a dual-microphone system to allow you to use them during calls when connected to a smartphone that supports the Bluetooth HFP profile. In addition to traditional calls, the headphones will work with many apps that use Voice over Internet Protocol (VoIP), such as Skype or FaceTime. The dual-mic system helps reduce wind and background noise to ensure an exceptional far-end experience, while sidetone lets you hear your own voice so you sound natural when speaking on a call. QuietComfort 35 wireless headphones II also support HD Voice.