Yes, you can! Many plant based milks such as almond, soy milk, coconut and even cashew milk work well for Instant Pot yogurt. Be sure to use a high-quality, unsweetened variety of plant milk when making your yogurt. Also make sure that the cultures you are using are appropriate for the type of milk you're using. We love soy yogurt. It's a great diary free yogurt option and making yogurt is always so fun!