Mild to moderate side effects of taking zuranolone for 14 days were reported. These included:
• drowsiness
• dizziness
• sedation
The clinical trial shows subjects did not lose consciousness, experience withdrawal symptoms, or experience increased suicidal ideation or behavior.
Like other forms of antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs), some amount of zuranolone may be found in breast milk.
“We reported at the International Association for Women’s Mental Health 2022 Regional Meeting that compared with the maternal dose, amounts of zuranolone in breast milk were low,” Deligiannidis said.