The first major difference between WordPress and WooCommerce is that WordPress is a standard publishing platform while WooCommerce is an eCommerce system. Although WordPress is a standard platform, it does have limitations that aren't ideal for eCommerce sites. For instance, WooCommerce doesn't integrate with payment processing systems like PayPal. It also won't give you any control over how your store looks, and you will have to use different styles and layouts for your store.