This really has to do with personal preference for the most part. If you are sensitive to smells or hate certain smells, fragrance-free may be the best choice. However, there are some things to know about the fragrances in dish soap. The main thing is that manufacturers don’t have to list the fragrance ingredients. This means that some of the ingredients may not be safe or something that you want in your soap. If you find a natural and/or organic soap that has some fragrance, you’re likely going to be safe with a little fragrance. But, it’s always best to find out where that fragrance is coming from if you can.