Real pearls are very delicate and soft. Cleaning them regularly is not recommended at all. However, you can clean them with a damp cloth only as needed. If your pearl earrings have become visibly stained, you can mix a solution of lukewarm water and mild dish soap, and then dip a soft cleaning cloth in it and wipe the pearls. It is not a suggested idea to submerge your pearl earrings in water for too long.