They can be used anytime of the day except immediately after meals. We suggest using it for at least 5 (and preferably 15) minutes prior to breakfast, which will help you get your day off to a good start. Use it just before lunch too! Remember, medical authorities recommend that we be completely relaxed before eating. Similarly, 15-30 minutes before dinner will help prepare you for the what can often be the heaviest meal of your day.One of the most gratifying times to use Niagara‘s Cyclo-Therapy devices is in the evening before retiring to bed. Your day's work is done and dinner has been digested, and there’s nothing better than a cyclo-therapy session. You'll feel your tension fade away, and the gentle cycloid vibration massage will relax you to the point that you'll be ready for sleep - a deep, restful, completely relaxed and drug-free slumber.