A computed tomography scan CT scans are often used to aid in the initial diagnosis of bone cancer and to determine whether the disease has progressed to other parts of the body. CT images might potentially be utilized to guide the biopsy needle. Other imaging tests include X-rays, magnetic resonance imaging (MRI), and positron emission tomography (PET). Bone tumors can be diagnosed using any of these techniques. X-rays use high-energy beams to produce images on film or digital detectors. These images provide information about the density of bones and tissues. Radiologists can identify abnormalities such as fractures, osteopenia (low bone mass), and tumor deposits. MRI uses magnetic fields and radiofrequency pulses to generate highly detailed pictures of the brain, spine, chest, and abdomen. This method does not involve exposing patients to ionizing radiation like x-rays. PET is similar to CT but uses radioactive tracers that are injected into the blood stream or taken by mouth to identify areas with increased activity in the bone tissue. PET provides more accurate information about the location of tumors and metastases than radiographs. Bone cancer treatment depends on the type and stage of the disease. For most patients, chemotherapy and radiation therapy are used together as part of their combined modality approach. Chemotherapy drugs kill both normal and cancerous cells, while radiation kills only cancer cells. Both therapies work best if used in combination.