Yes. Ruketo is safe. When your body is in a state of ketosis, ketones can naturally exist in your body. Ruketo works by providing you the benefits of being in ketosis, but Ruketo does it from an exogenous (meaning, from outside your body) source (that is, Beta-HydroButyrate, or keto salts). If you do, however, suffer from any medical condition, you may want to consult your doctor before starting any new diet or new nutritional supplement.