There's no point in paying extra and carrying extra weight if your bike doesn't have bolts of a certain size.
Foe example, many multi-tools include Torx heads, although these are relatively rare on bikes, so you may want to look for a multi-tool that covers these.
On the other hand, many thru-axles on disc brake bikes don't come with levers. The most common thru-axles use a 6mm hex head. Newer tools almost invariably include this, but some older tools don't have one, so check that you will be able to remove your wheel with your tool if you need to repair a flat.