Potentially, depending on the ingredients. For example, if a menopause supplement has ingredients for balancing hormones, such as diindolylmethane (DIM), or boosting nitric oxide then it may benefit female arousal.Thomson, C., Chow, S. Roe, D., Wertheim, B., Chalasani, P., Altbach, M., Thompson, P., Stopek, A., & Maskaranic, G. (2017). Effect of Diindolylmethane on Estrogen-related Hormones, Metabolites and Tamoxifen Metabolism: Results of a Randomized, Placebo-controlled Trial. Cancer Epidemiology Biomarkers & Prevention 1, 26(3), 435. And prescription menopause medications usually involve hormones — estrogen, progestins, or both — so they may also help arousal by restoring the balance of your hormones.U.S. Food and Drug Administration. (2019). Menopause: Medicines to Help You. FDA. For more information on menopause supplements and other treatments, you can check out our comprehensive guide to the best menopause supplements.