Yes, it will take about double the time as a defrosted or fresh turkey. Cook at 325ºF to thaw it for the first 2 to 3 hours. Once softened, add the butter or oil and seasonings. Roast until the thickest part of the breast is 160 to 165ºF (71 to 74ºC), and the thickest part of the thigh reaches 170 to 175ºF (76 to 79ºC).