As it was when I received it, I did not feel the need to clean it, so I cannot say with absolute certainty. These bags have what seems to be a rubbery lining (vinyl, according to Coleman's) in addition to a hard floor panel. Machine washing would not be recommended for both reasons. If I had to do so, I would probably only spot clean it with cold water first, possibly hand wash it in a basin if it truly needed something more drastic. Only air dry, for sure.