Trimix is made up of three main components: Papaverine, phentolamine, and alprostadil. These ingredients work together to help relax the muscles and widen the blood vessels in the penis. This boost in the bloodstream is what allows men with erectile dysfunction (ED) to get and keep an erection. In simple terms, Trimix is like a special mix of ingredients that helps your body do its thing when it comes to getting ready for some action.