In most cases, the answer is yes. However, there are some caveats. It is typically not advisable to use automatic transmission fluid in manual transmissions due to the different needs of each type of transmission. You should remember that automatic transmission fluid acts as both a lubricant and a hydraulic fluid. Manual transmissions, however, only need a lubricant. Some manufacturers suggest using ATF as the lubricant in their manual transmissions, but you should always refer to your owner’s manual to determine the type of fluid needed in your vehicle.