Nasal abrasions, congestion, mucus production, ear pain from tubing pressure, and skin irritation are possible but can often be mitigated by using humidification, repositioning and lubricating the cannula, and switching to padded tubing. Maintaining the concentrator with fresh filters reduces irritants. Weaning off oxygen under supervision when clinically appropriate also prevents dependence. Patients should alert their doctor about any bothersome side effects.