Nitrile offers resistance to oil and solvent across a wide array of temperatures. This synthetic rubber has exceptional resistance to engine oil and gasoline, good resistance to acids, and superior resistance to petroleum products hydraulic fluids. On the other side, Neoprene rubber has average resistance to oils and petroleum products, but it has significant resistance to sunlight, ozone, and weather. Note that both nitrile and Neoprene have the same properties, but their applications make them different from each other.