This really depends on what type of vacation you want to have. If you want to primarily visit Disney World, there are a number of hotel options by the resort. These can get pretty pricey so it is also a good option to check hotels in Kissimmee and Lake Buena Vista for more economical options. If you're more interested in exploring Orlando, staying Downtown puts you close to the action and also has easy access to all parts of the city and surrounding areas. There are very few budget hotel options in Downtown Orlando though so it is a good idea to check AirBnbs.