Botulinum toxins are biologics, produced from a bacterium called Clostridium botulinum. They are used to inhibit the transmission of specific chemical signals from nerves, primarily those signals that cause muscular contractions. Botulinum toxin type A injections temporarily relax the facial muscles that cause wrinkles between the brows, reducing their appearance. DAXXIFY is the only FDA-approved, long-lasting frown line treatment (neuromodulator) to help smooth moderate to severe lines between the brows, lasting on average 6 months and up to 9 months in some.¶ Injections of specific botulinum toxin formulations are also utilized in the treatment of medical conditions. ¶At least 50% of patients in clinical studies had no or minor frown lines 6 months after treatment. Between 3% and 5% of patients in clinical studies had no or minor frown lines 9 months after treatment. In other safety studies, between 5% and 17% of patients still had noticeable improvement 9 months later.