You probably shouldn’t. Spinosad is an organic insecticide derived from soil bacteria, which will infect and kills thrips. However, it has also been banned from cannabis operations in five states and Canada. While it may be safe to consume after harvest, no information exists regarding how safe it is to smoke. Ingesting a chemical is much different than combusting it and inhaling the vapors. Insecticidal soaps have not been shown to be harmful to smoke.