Yes, sea bass should always be cooked fully to an internal temperature of 145°F (63°C). This will ensure that it is safe to eat and that all bacteria have been killed.   When cooking sea bass, use a food thermometer to make sure the internal temperature has reached 145°F. Additionally, you should cook sea bass until it is opaque and flakes easily with a fork. This will ensure that the fish has been properly cooked and is safe to eat.