Artificial Intelligence (AI) is being applied in all the more medical fields. In Gastroenterology, the remarkable progress achieved in the field of Endoscopy in recent years is further complemented with the use of AI. The emerging applications of AI use complex algorithms to support the human experience and improve the effectiveness of endoscopists.The use of AI assists endoscopists to detect polyps in the large bowel, even microscopic ones, which are then characterized early in terms of their histology and the depth of invasion in the bowel wall. This assists endoscopists in making an early diagnosis, and taking decisions in real time on how to treat their patients.In the coming months, new protocols will be published that will help endoscopists to detect, study and characterize:Barrett's esophagus and esophageal cancergastric cancermonitor idiopathic inflammatory bowel diseasescapsule endoscopyNaturally, AI cannot replace an experienced endoscopist, who will not just rest on the results provided by it. However, apart from being another impressive weapon in the arsenal of a modern endoscopist, this technology can also play a very important role both in training new endoscopists and in transferring accumulated knowledge.At the new IASO Endoscopy Department, we have the privilege of using cutting-edge technology, with the latest ELUXEO systems by Fujifilm, which integrate innovative and groundbreaking technologies. High-resolution imaging, magnifying electronic chromoendoscopy using Linked Color Imaging (LCI) and Blue Light Imaging (BLI), and the new state-of-the-art CAD-EYE endoscopy software make up the most modern and integrated system in endoscopic imaging. This system is now available at the IASO Endoscopy Department, assisting in optimizing the quality of gastrointestinal endoscopy.The use of these techniques, and primarily the use of AI, greatly increases reliability and diagnostic accuracy in colonoscopy, effectively contributing to the prevention of colon cancer. The IASO Endoscopy Department now uses new Artificial Intelligence (AI) software, becoming one of the first departments in Greece and Europe equipped with such groundbreaking technology.