"Lo Siento" is the most common way to say sorry in Spanish. It's a general apology that can be used in any situation. 2. "Perdón" is also a common way to say sorry. It has a more formal tone and is often used when you've made a mistake. 3. "Disculpe" is the most formal way to say sorry. It's often used when you've made a mistake, or when you need to ask for forgiveness.