The two main areas to consider are International Drive and Lake Buena Vista. International Drive, often referred to as I-Drive, is a bustling tourist hub filled with hotels, restaurants, and entertainment venues. Located near some of Orlando's most famous attractions such as Universal Studios and SeaWorld, staying on International Drive gives you easy access to these popular destinations.
On the other hand, if you're mainly interested in visiting Walt Disney World Resort during your stay in Orlando, Lake Buena Vista is an excellent choice. This area is home to numerous Disney-owned hotels and resorts as well as vacation rental homes. Staying here offers convenience since you'll be within close proximity to all four theme parks: Magic Kingdom Park, Epcot Park, Disney's Hollywood Studios Park, and Disney's Animal Kingdom Theme Park.