Orphan Major (Full fee)£102,028 Orphan Major (exceptional circumstances in which point G of Part IV of Annex 1 in the 2001 Directive applies)£32,705 Orphan Complex (Full Fee)£28,207 Orphan Standard (Full Fee)£10,342 Notes: Where the licensing authority grants an orphan marketing authorisation, the following percentage of the fee otherwise payable under regulation 12(1)(a) in connection with the application for that authorisation shall be refunded, if it has not yet paid, shall be waived (a) Small and medium (SME) company: 100% (b) Applications not made on behalf of SME but which point G of Part IV of Annex 1 to the 2001 Directive applies: 50% (c) Any other case: 10%