Polynucleotides work by stimulating the natural production of collagen, elastin and hyaluronic acid within the skin, rather than injecting hyaluronic acid directly. This accounts for its excellent safety profile and allows it to be used in delicate areas such as the surrounding eye area, which is associated with complications from dermal filler treatment. Unlike skin boosters, which enhance skin quality through hydration and nourishment, biostimulators like PhilArt promote deeper skin rejuvenation by stimulating collagen and elastin production.