The most common symptoms of peripheral neuropathy can include: ● Burning pain radiating in hands or feet ● Pins and needles in the extremities ● Numbness and tingling ● Weakness in hands, arms, legs and or feet ● A knotted feeling in the soles and palms ● Pain from the lightest touches ● Difficulty walking ● Pain from the pressure of walking ● Balance problems ● Inability to grasp with the hands ● Cramping of the feet ● Fingers twisting and locking ● Pain when twisting the wrists ● Hands and feet feeling tired or heavy ● Night pain and sleep difficulty ● Restless legs and feet ● Pain that seems to come even from the sheets or covers on your feet at night