Derek McLane has received several prestigious awards for his work in scenic design. He won Outstanding Scenic Design for a Musical at the Drama Desk Awards for Moulin Rouge! and also received the Outstanding Scenic Design award from the Outer Critics Circle Awards for the same production. Additionally, he was honored with the Tony Award for Best Scenic Design of a Musical for Moulin Rouge!. For How To Succeed in Business Without Really Trying, he won the BroadwayWorld Award for Best Scenic Design. He received the Outstanding Set Design award at the Drama Desk Awards for Anything Goes and was recognized at The Hewes Awards for Scenic Design for 33 Variations. McLane also won the Tony Award for Best Scenic Design of a Play for 33 Variations. His work on The Voysey Inheritance and Intimate Apparel earned him Outstanding Scenic Design awards from The Lortels. Furthermore, he received Outstanding Set Design - Play awards at the Drama Desk Awards for I Am My Own Wife and East is East.