Balding can be a process of aging and genetics, especially in the case of men. Nearly 40% of men show some signs of balding by age 50. In such cases, treatment by Xeljanz or other Disease Modifying Rheumatoid Arthritis drugs (DMARDs) may not be appropriate. But suppose other symptoms indicate the possibility of autoimmune disease. In that case, this kind of treatment may be indicated.
However, hair loss is far more likely to be an underlying condition for women. Women are roughly twice as likely to have an autoimmune disease as men of the same age.
Unlike the two main types of balding in men, which are crown balding and receding hairline, in women the pattern of hair loss is different, with a diffuse thinning of hair on the scalp or a widening of the center part, while the frontal hairline usually remains intact.