Calathea Burle Marx is considered mildly toxic. While it is not highly harmful to humans or pets, it contains compounds that can cause mild gastrointestinal discomfort if ingested in large quantities. Keeping the plant out of reach of children and pets is essential to prevent accidental ingestion. Additionally, some individuals may experience skin irritation or allergic reactions when in contact with the leaves or sap of Goeppertia burle-marxii. Handling the plant cautiously and washing the affected area if any skin irritation occurs is advisable.