No not really. Most domestic sprayers are designed to be easy to use for the average homeowner and come complete with an easy to understand manual and often an instructional DVD that will walk you through the setup, using of, maintenance & cleaning of your machine.
There is also a huge selection of videos on Youtube that cover in-depth, the main brands and sprayers, how to use them and troubleshooting.I'd advise using a slower spray mode (if you have adjustable pressure) practicing on something that doesn't require a perfect finish, such as painting fences.