Meatballs are generally less likely to fall apart in a slow cooker compared to other cooking methods, like frying or grilling, as the slow, gentle heat helps them hold their shape. Additionally, handling the meatballs carefully when placing them in the slow cooker and stirring them gently during cooking can also minimize the risk of them breaking apart. We recommend using frozen meatballs, but you can use homemade meatballs as well.