Methamphetamine and amphetamines are both stimulant drugs, but there are some key differences between them. Methamphetamine, a synthetic version of the stimulant amphetamine, is utilized for its pleasurable effects and a high potential for abuse. Amphetamines, on the other hand, are less likely to be abused due to their legal status as a medically prescribed treatment for conditions like ADHD and narcolepsy.