The timeframe for Low Dose Naltrexone (LDN) to exhibit its effects for weight loss can vary from person to person. Generally, it may take several weeks to a few months to notice significant changes. Some individuals might start to see effects in terms of appetite reduction and weight loss within the first few weeks of treatment, while for others, it might take longer. The average time reported for noticeable results is typically around 8 to 12 weeks. It's important to maintain consistent use as prescribed and combine LDN with a healthy diet and exercise regimen for optimal results. Additionally, the response to LDN is highly individualized, and not everyone may experience the same level of effectiveness. Regular follow-up with a healthcare provider is essential to monitor progress and make any necessary adjustments to the treatment plan.