Lab of Lunacy is only available at Stake casino. Stake casino happens to be one of the most user-friendly and flexible online casinos around, particularly for those interested in crypto gambling, and has very convenient options in terms of banking as much as game play.
The only catch is that you will have to create an account to play there. This is fairly standard mind you, certainly for real money gambling as the casino obviously needs some basic information to accommodate that.
So in short, yes, you will need to register an account, even to play in demo mode.