BOTOX treatment is individually tailored to your unique needs and aesthetic goals. The number of injections you require will depend on the number of treatment areas: For frown lines between the eyes, you will need five injections into the muscles between the brows and in the forehead. For lines on the forehead, your injections will vary depending on the severity of your lines. For crow’s feet, you will need an injection in three different areas of the muscle that frames the side of the eye, and three more injections for the other eye.