Writers with full-time jobs may face challenges such as limited time, mental fatigue, creative burnout, and balancing work-life commitments. To address these challenges, writers can consider setting realistic writing goals, utilizing tools like time management apps or writing prompts, seeking support from writing communities or accountability partners, and practicing self-compassion. It's essential for writers to acknowledge their limitations, prioritize self-care, and find ways to integrate writing into their daily routines without overwhelming themselves.