8 heart health supplements to take – and one to avoid Multivitamin & mineral. Vitamins and minerals taken in appropriate doses may aid in lowering heart disease risk. ... Coenzyme Q10 (Co Q10) Coenzyme Q10 (CoQ10) is a substance similar to a vitamin. ... Fiber. ... Omega-3 fatty acids. ... Magnesium. ... L-Carnitine. ... Green tea. ... Garlic. Jan 30, 2018