Bed sheets should be cleaned before first use and at least every two weeks. If you sleep hot and sweat often, or have pets you should consider washing your sheets every week (this is especially important for people with sensitive skin).
Always read the wash instructions for your bed sheets. For best results, wash separately from other items to reduce wear and minimize wrinkling.. Often if washing every week with a low soil level cold water is fine; however- if especially soiled hot water can be used. In order to reduce wear and wrinkling, sheets should always be washed alone. No bleach.