Long-term exposure to mercury can lead to neurological issues such as mood swings, memory loss, and motor skill impairment, along with damage to the kidneys, lungs, and cardiovascular system. Cadmium exposure primarily affects the kidneys and can cause bone demineralization and increased cancer risk. Prolonged exposure to inorganic arsenic is linked to skin diseases, and cancers of the skin, bladder, and lungs, and can impair intellectual development in children.