Yes. You can place multiple wagers on a single spin of the roulette wheel. For example, you could straight bet the 1, split bet the 1 and 4, and then add a column bet for good measure. Just remember that you normally don’t want to make wagers that essentially cancel out other active stakes. For instance, there is nothing to be gained by betting black and red. In fact, you could lose both wagers if the 0 or 00 showed up.