The main active compounds in slippery elm bark include mucilage, tannins and polysaccharides. It also has nutrients like vitamins and minerals. Mucilage forms a soothing gel-like substance when mixed with water. Tannins have antioxidant properties and astringent properties that help sooth irritation. Polysaccharides contribute to the prebiotic effect of slippery elm bark. They nourish beneficial gut bacteria and support a healthy gut microbiome. These compounds work together to contribute to slippery elm’s effects on digestive health and well-being.