Extremely accessible! The city has a network of buses, overground trains (U-Bahn), and underground trains (S-Bahn). I recommend getting a u003ca href=u0022https://www.visitberlin.de/en/berlin-welcome-cardu0022 target=u0022_blanku0022 rel=u0022noreferrer noopener nofollowu0022u003e72 hour Berlin Cardu003c/au003e, which includes access to many major tourist attractions in Berlin like the museums, as well as a public transport pass that can even get you to/from the airport.u003cbr/u003eu003cbr/u003eYou can also do a day trip to Berlin from major cities in surrounding countries including Amsterdam, Prague, Bratislava, Budapest, Vienna, Basel, Berne, Interlaken, Poznan, Gdansk, and Warsaw on multiple train services each day. By overnight train, you can also reach include Minsk, Moscow, Paris, and Zurich.