Bravecto Plus should be administered topically as a single dose every 2 months according to the dosage schedule (How to Use tab) to provide a minimum dose of of 18.2 mg/lb (40 mg/kg) fluralaner and 0.9 mg/lb (2 mg/kg) moxidectin.. Treatment with Bravecto Plus may begin at any time of the year and can continue year round without interruption.