Yes, you can, but manufacturers generally recommend allowing some time for a mattress to fully expand and air out. While it's safe to sleep on the mattress right away if needed, giving it time ensures it reaches its full capacity for personal comfort.
I’ve found that most bed-in-a-box mattresses, including the Nolah Natural 11, need about 24 to 48 hours to fully expand to their intended shape and firmness after being unpacked.
During this time, you might notice a slight odor, which is normal for new mattresses and should dissipate within a few days. Though I didn’t experience any odor with the Nolah Natural, which is a noted benefit of latex foam.