When it comes to getting the best audio, the location of noise reduction within the signal chain greatly affects the efficiency and effectiveness of the process. It is best placed in two spots: before and after compression. Setting your noise reduction before compression helps minimize unwanted frequency peaks that can otherwise occur with compression. Additionally, it is beneficial to put a second, less aggressive instance of noise reduction at the very end as a final filter for any remaining unwanted elements in your track. Doing this ensures that your track is free from any harsh, undesired frequencies and sounds.