Some pitching machines are only compatible with practice softballs and/or baseballs, which are lighter and may have a textured surface. Other machines only work with regulation softballs and/or baseballs. Some machines can use both practice balls and regulation softballs or baseballs. In that case, it’s a matter of personal preference.Some hitters like using regulations balls in a pitching machine because practice can better mimic actual game play. But practice balls are usually less expensive. They can also be thrown more consistently by a pitching machine. Whatever you decide, use balls that are all the same type and in the same condition to make sure that the pitches are as consistent as possible.