You can definitely save in different college savings plans at the same time. Many families in Massachusetts choose to save in both the U.Plan Prepaid Tuition Program and the U.Fund 529 College Investing Plan. The U.Plan allows families to lock in current rates on tuition and mandatory fees, so they use their U.Plan savings for those costs. Putting additional funds into a U.Fund account allows families to save for other expenses, such as room and board, books, and supplies.