Cushing's Syndrome is a condition which happens due to prolonged use of corticosteroids. The common symptoms include weight gain, fat deposits at the stomach region and the upper back between the shoulders (buffalo hump) or in the face (moon face), purplish or pink stretch marks (called striae) on the skin of stomach, thighs, breasts and arms. The skin also may become fragile, causing easy bruises. Though Cushing's syndrome is more common with oral corticosteroids taken for prolonged periods, topical and inhaled corticosteroids taken over a while also can cause Cushing syndrome.