Mechanism of action studies assist in identifying the target pathway of specific drug compounds. Thus, helping in the development of an efficient drug dosage regimen and minimizing off-target effects. At NorthEast BioLab, we offer MOA studies for robust lead optimization.
Target Identification and Validation
NorthEast BioLab experts conduct MOA studies for achieving target-specific inhibition of many cellular substrates such as signaling kinases. The process involves treating cells with compounds at different concentrations, preparing cell extracts, and quantifying protein levels through Western blots and ELISA assays.
Compound Profiling
NorthEast BioLab scientists help with compound profiling to ensure that target activities of the drug compounds minimize toxicity. Using this MOA procedure, we can identify the efficacy and safety profile of a particular drug compound.