Many fans believed that the famous musician had a condition called heterochromia, which means that each eye is a different color, but David Bowie actually had anisocoria, a condition which causes an enlarged pupil to appear darker than the other. This condition developed when Bowe’s pupil was damaged in 1962 after he got into a fight with his friend George Underwood. During the fight, George's fingernail hit Bowie's eye when he threw a punch at his face, causing the dilated pupil.