On July 9, 1992, the Cincinnati Reds traded him to the Boston Red Sox in exchange for Tom Bolton. He was given free agency on November 2, 1992. On November 27, 1992, he signed as a free agent with the Boston Red Sox. The Boston Red Sox traded Paul Quantrill to the Philadelphia Phillies on July 31, 1994, in exchange for Mike Sullivan (minors) and Wes Chamberlain. The Phillies sent John Valentin to the Red Sox on August 3, 1994, to complete the trade. Billy Hatcher played two seasons for the Red Sox, batting.273 with 15 home runs and 74 RBIs. He finished his Red Sox career with a.293 average, three home runs, and 26 RBIs in 99 games. After his two years with the Red Sox, he retired from baseball to take a job with MassMutual after the season. He died on January 4, 2018 at the age of 59. His wife, Jennifer, and son, Thomas J. Hatcher, also became members of the Red Sox organization. His son played minor league ball for several teams between 1996 and 2001 before becoming an assistant coach for the Colorado Rockies. In 2002, Thomas J. Hatcher managed one game for the Red Sox during their playoff run. He lost that game 1-0 to the New York Yankees.