The answer will depend on your case. It is more likely to work in women with unexplained infertility, such as cervical mucus problems with ejaculation. However, it will not work for women suffering from fallopian tube disorders or severe sperm impairment. In general, women over 35 years old can expect success rates of up to 20% in the first three IUI attempts. However, the success rate depends on the medication you are taking.