Principle: The radiopharmaceutical is uptaken up by Kupffer cells in the liver after administration and, due to the presence of phagocytic reticuloendothelial cells in the spleen, is also uptaken up in the spleen. The distribution of the radiopharmaceutical in the parenchyma of the liver and spleen is proportional to the phagocytic capacity of the RES. Indications: deposits in the liver cirrhosis Patient preparation: none Duration of examination: approx. 40 minutes Radiopharmaceutical: 99mTc – colloid Method of application: Intravenous Examination methodology: The patient is injected intravenously with the radiopharmaceutical either under the gamma camera (dynamic study is started immediately after application) or in sitting position. The examination itself starts 20 minutes after application. Six basic projections are taken. To increase the sensitivity and specificity of the examination, targeted SPECT is added.