Infertility is the main complication associated with primary ovarian insufficiency. POI treatments cannot restore ovarian function, so hormone replacement therapy will not increase your chances of getting pregnant.
Other possible complications include:
Osteoporosis: Oestrogen is responsible for helping to keep bones strong. Low levels of oestrogen increases the risk of the bones becoming weak and brittle, known as osteoporosis. Brittle bones are more likely to break than bones that are healthy and strong.
Heart disease: Depleted oestrogen levels earlier in life have been shown to heighten the risk of heart disease.
Depression or anxiety: The risk of infertility and other complications caused by POI can trigger feelings of depression or anxiety in some women.