The most recommended way to prevent altitude sickness is progressive adaptation, i.e., ascend moderately to adapt to the decrease in oxygen as you gain altitude. We recommend spending at least one day in Cusco without extreme physical effort to adapt to the altitude.
It is also important to take care of your diet, eating light, easily digestible food will help in the acclimatization process. Stay hydrated, drink at least 4 to 5 liters of water while in Cusco. Sleep at least 8 hours a day before your tours, keep your body rested without too much physical effort. As a natural remedy, you can drink coca tea or chew it during your stay. The coca leaf will help you oxygenate at high altitude more efficiently.