Surgery is the most common colorectal cancer treatment. Surgery is used to remove the tumor and surrounding tissue. A portion of the colon or rectum may need to be removed, and a colostomy may be required—permanently or temporarily, depending on the extent of the cancer and how much of the colon or rectum is removed. Other treatment options include chemotherapy and/or targeted therapy drugs, which may also be used in addition to surgery. Radiation therapy is usually an option only for rectal cancer, not colon cancer.