Keeping your skin hydrated will make it less prone to wrinkles so you certainly want to use a moisturizer regularly. Which moisturizer you use will depend on your skin type because different moisturizers tackle different problems. It’s usually recommended to moisturize after exfoliating or bathing but this will depend on the type of skin you have and any ongoing skin problems. If your skin has a tendency to be dry, it’s likely that you’ll need to moisturize more than someone with oilier skin. Your dermatologist will be able to tell you what type of moisturizer to use and how often to apply it.