Primary care providers can effectively communicate the limitations of the blood-based CRC screening test by engaging in thorough discussions with patients. It is crucial to explain that while the blood test may have certain advantages, such as convenience, it is not a standalone test for CRC screening. Providers should emphasize that the blood test has lower sensitivity and specificity compared to traditional screening methods like colonoscopy or stool tests, meaning it may miss detecting precancerous polyps. Patients need to understand that a positive result from the blood test necessitates further evaluation through a diagnostic colonoscopy to confirm the presence of CRC or precancerous lesions. By providing clear and detailed information, setting realistic expectations, and stressing the importance of follow-up procedures, primary care providers can ensure that patients make informed decisions regarding their CRC screening options.