Yes, although depends on your definition of low dose. In the old days, pills had 110mcg of estrogen and then 50 mcg. So when research says low dose, they mean anything under 50 mcg of estrogen. When we say low dose at Pandia Health we mean anything less than 30 mcg of estrogen which is NOT good for your bones if you are under the age of 30 years old. We recommend that you use at least 30mcg if you are under 30 years old. We recommend that you use at least 30mcg if you are under 30 years old.