The FDA has approved an over-the-counter product that combines acetaminophen and ibuprofen in one medication called Advil Dual Action. This ibuprofen and acetaminophen combination can be used to treat minor aches and pains including headache, backache, toothache, menstrual cramps, muscle ache and arthritis pain.4 The combination of acetaminophen and ibuprofen relieves pain more effectively than either ingredient on its own.5