Yes, you can load the chamber of the Solo II Glass Aroma Tube with as much or as little as you prefer. For microdoses, lightly tamp down a small amount of herbs so it stays packed together. Alternatively, just load the chamber of the Solo II Glass Aroma Tube, preheat the device, insert the tube for 1-2 draws, then remove the Solo II Glass Aroma Tube and cap it with a Silicone Stem Cap to preserve the remaining material for future use.