In terms of closing odds, the biggest underdog to win a UFC bout was Shana Dobson, who came in at +950 against Mariya Agapova, who was a -1400 favorite to win their bout at a UFC Fight Night event in 2020. Dobson won the fight via TKO, cashing as an almost 10-1 underdog. The biggest upset in a title fight came at UFC 69, when +850 underdog Matt Serra defeated welterweight champion Georges St-Pierre via TKO in 2007.