Sickle cell disease is a big reason to start using glutamine, and this is also an FDA-approved prescription medicine for it. It also reduces the chances of death in people with severe burns, and it helps to prevent hospital-acquired infections. For those who have HIV/AIDS, glutamine helps the body to absorb food better. Major abdominal surgeries also use it post-treatment for faster recovery. It is directly related to making intestinal health better and is known to improve exercise performance. Treating short bowel syndrome is also one of the reasons why people turn to L-Glutamine. Alongside, some of the reasons why people see its deficiency is because of shock or extreme stress, significant infections, radiotherapy or chemotherapy, HIV or AIDS, Crohn’s disease and inflammatory bowel diseases.