It might fall apart due to a few common reasons. First, ensure you have adequate binding agents like flax eggs or breadcrumbs to hold it together. Avoid overmixing, as excessive mixing can break down the structure. Also, be mindful of moisture levels, draining and patting dry canned ingredients can help. Don't overcook it, as this can make it dry and crumbly. Use a meat thermometer to check for doneness. Finally, allow your meatloaf to rest briefly after baking to help it firm up. By addressing these factors, you can prevent your meatloaf from falling apart.