Yes, you can exercise while you’re using Eligard. In fact, a study of males* taking hormone therapy such as Eligard for prostate cancer showed that exercise may be beneficial. Exercise can lead to positive changes, such as fat loss and increased muscle strength.However, taking Eligard may make you feel uncomfortable or tired, so you might not feel like exercising. (For more on the side effects Eligard can cause, see the “Eligard side effects” section above.) You also may not be able to work out easily if you have back pain or certain other symptoms from prostate cancer.Talk with your doctor about exercising safely during your treatment with Eligard. They’ll be able to recommend the right amount of exercise for you to get during your treatment.* Sex and gender exist on spectrums. Use of the term “male” in this article refers to sex assigned at birth.