The fundamental distinction between NFT and DeFi is that NFT refers to unique digital assets, whilst DeFi refers to the internet's financial system. DeFi runs on smart contracts on block chain on its platform and eliminates intermediaries, whereas NFT holds a unit of data that is unique and non-interchangeable. NFT facilitates tokenization of assets. Typically, the tokens are reasonable value propositions. The asset's value is locked. NFT's worth varies depending on who you ask and how much you pay. The value of the offering is a big factor in determining its worth. DeFi, on the other hand, allows for financial transactions and services. Decentralized applications are used to run the platform. Smart contract programmes allow transactions to be made directly between participants.