That depends on what's important to you. If your keyboard sits in front of your desk and never moves, it's probably not important. But if your keyboard is constantly on the go with you in a bag, or needs to connect to multiple devices over Bluetooth, wireless is the way to go. The latest boards can connect to three or four computers (or phones or tablets) easily, and last for months and months on a charge...as long as you take it easy with the backlighting. There's one exception: gaming. If you're playing PC games with your keyboard, you want to use a wireless connection with low latency, and that means a dongle you plug in. Unlike some older wireless keyboards, and just like newer kinds of mice, modern wireless gaming boards have almost zero latency. That means you'll never notice a gap between when you press a button and when your character reacts on screen. Just don't use Bluetooth (even if it's an option), as the high latency and crowded wireless bands can cause performance issues.