If you’re already a sewing guru even without a thimble, then incorporating the device will be a walk in the park. You start by wearing the thimble on your middle finger.
How you hold the needle will be no different than usual. You use your thumb and index finger, and with the sharp end, you’ll puncture the fabric you intend to sow. On the eye-end of the needle, the thimble will provide stability thanks to the texture. Lastly, you can use the middle finger covered by the thimble to push the needle the rest of the way through the fabric.