This is a question you should ask yourself when considering how much load you'll be carrying on your trip. We'd advise you to go frameless if you're going on an ultralight trip. It will make you faster and enhance comfort because you're only dealing with minimum load. Internal frames are better for heavier loads. And they give you better stability on rugged or uneven terrain. If this sounds like what you'll be dealing with then read our review on the best internal frame backpacks. External frames are best suited when dealing with heavy loads. A major benefit of these is they provide great ventilation. External frame backpacks also come with many features that enhance organization. Take a look at some of the best new external frame backpacks to help you get ready for your next trip.