My best suggestion is to let the lasagna thaw out in the refrigerator which may take 24 hours or more. Then bake for 45 minutes at 350 degrees, cover, and remove cover for another 10 minutes. If baking a frozen lasagna, bake at a lower temp (325 degrees) for an hour or more, check to see if the center is unthawed, and then raise oven temp to 350 degrees and bake again until piping hot.