Most heart tests recommended for individuals in their 40s are non-invasive and generally not painful. Blood pressure measurement, lipid profile, fasting blood glucose, and BMI calculation are simple and quick. Electrocardiogram (ECG or EKG) involves placing electrodes on the chest to record heart activity and is painless. While an echocardiogram is an ultrasound of the Heart, it is non-invasive and painless. The stress test may involve physical exertion but is not typically painful.