Again, it's not easy to simply give a "yes" or "no" answer. It really depends on your overall health. If you don't have any coexisting conditions, aren't pregnant or nursing, and you're able to take the medication exactly as prescribed by your doctor, the risk of adverse events or serious side effects is minimal.
Most people do experience some side effects on Accutane, though, unless they're on a very low dose. So bear in mind that even when Accutane is "safe," it still comes with some risks.