Yes, you can wash Senegalese twists. Dilute some shampoo into a spray bottle, then separate your hair into four sections. Work through one area at a time, and soak your roots with the spray bottle, massaging it really well into the scalp. Rinse it out in the shower, allowing it to run through the ends. Squeeze out any excess water, then apply a good conditioner and oil blend from roots to the ends, avoiding the scalp. Rinse thoroughly and squeeze out excess water before gently towel or air drying.