The choice of fabric for a men's shirt depends on your personal preference and the occasion. Common shirt fabrics include cotton, linen, silk, and blends. Cotton is a versatile option known for its breathability and comfort. Linen is lightweight and ideal for warm weather, while silk offers a luxurious feel. Blended fabrics combine the benefits of different materials. Consider factors like the season, desired texture, and care requirements when selecting the fabric for your shirt.