Saxenda has been studied in adults and adolescents with and without Type 2 diabetes. Over the course of 56 weeks, these studies compared Saxenda to a placebo (an injection without medication). Adults with Type 2 diabetes lost an average of 5% to 6% of their initial body weight in one study. People who took Saxenda lost about 3% to 4% more weight than those who took a placebo. Another study found that adults without Type 2 diabetes lost an average of 8% of their initial body weight, approximately 5% more weight loss than the placebo group. According to the research, Saxenda can help you successfully lose weight. However, keep in mind that it works best when combined with a low-calorie diet and exercise.