Yes, however you're going to need about 2 cups of the separated cream for this recipe. I found that each can of coconut cream yielded about 1 cup of cream. If using coconut milk, you may need an additional can. A few other things to keep in mind - make sure to refrigerate for at least 8 hours and don't mix it up or shake it. You're trying to get the cream to separate and harden and will not be using the coconut liquid. Also, some brands contain guar gum or other stabilizers that may not allow the cream to separate.