Serine/threonine protein kinase has a potential catalytic ability to transfer the γ-phosphate group in ATP to the specific amino acid residues of protein substrate to make protein phosphorylate. It mainly plays a regulatory role in DNA replication and mitosis, as well as in the process of transcription. For example, the process of nuclear translocation of transcription factors regulates the binding ability of transcription factors and DNA and regulates the activation activity of transcription factors. Moreover, phosphorylation is closely related to tumorigenesis, which can promote changes in gene expression and other cellular responses.