The main difference between hemp oil and CBD oil is that hemp oil has little to no CBD content. Hemp oil is often used interchangeably to describe different hemp extracts such as hemp seed oil and CBD oil, while they are two completely different products.Hemp seed oil vs. CBD oil Hemp seed oil is made by cold-pressing the seeds of the industrial hemp plant. Hemp seed oil is rich in omega fatty acids, vitamins, proteins and considered a superfood. At the same time, hemp seed oil is devoid of cannabinoids. CBD oil is extracted from the flowers, leaves and stalks of the hemp plant (full plant extraction). Therefore, full-spectrum CBD oil contains high concentrations of cannabinoids and terpenes.