Mixing psilocybin with other drugs or substances can cause psychological and physical risks. Psilocybin itself can have profound effects on perception, cognition, and consciousness, and combining it with other substances can lead to unpredictable interactions and heightened risks.
Increased Risk of Negative Effects: Combining psilocybin with other substances can amplify the potential negative effects. For example, mixing with alcohol or certain medications can increase the risk of nausea, anxiety, paranoia, and even dangerous physical effects.
Unpredictable Interactions: Psilocybin can alter how the brain processes sensory information and emotions. Combining it with other substances can cause unpredictable and intense interactions that may be uncomfortable or distressing.
Reduced Control: Taking mushrooms with other substances can impair the ability to make rational decisions, potentially leading to risky behaviours or accidents.
Physical Health Risks: Psilocybin can cause changes in heart rate and blood pressure. Combining it with substances that also affect cardiovascular function, such as stimulants, can lead to cardiovascular strain.