There are manufacturer instructions for each piece of CPAP equipment on how often you should clean and replace them. We recommend that you run your CPAP mask, headgear, hose, and humidifier tank through a cleaning cycle once a day. With the addition of a SoClean, VirtuClean, or Lumin to your daily sleep therapy routine, you can ensure that your CPAP is 99% germ-free each time you use it. With only a few minutes and the push of a button you can rest easy knowing that you are getting the cleanest and most effective sleep therapy possible.