Though there are many different hyaluronic acid fillers on the market, you and your surgeon should choose the formula that is tailored most closely to your specific needs. If you have moderate or deep laugh lines, such as marionette lines or nasolabial folds, that are making you look older than you really are, Restylane Defyne or Restylane Refyne may be a good choice for you. With that said, your plastic surgeon will help you determine what formula will best suit your needs.