An MTHFR deficiency can result in a genetic condition known as u003ca rel=u0022noreferrer noopeneru0022 href=u0022https://www.webmd.com/children/what-is-homocystinuria#1u0022 target=u0022_blanku0022u003ehomocystinuriau003c/au003e. This is due to a lack of folate. This condition is commonly caught during newborn screenings. Proper treatment prevents its effect on a child’s life. If left untreated, however, it can lead to u003ca rel=u0022noreferrer noopeneru0022 href=u0022https://rarediseases.info.nih.gov/diseases/2734/homocystinuria-due-to-mthfr-deficiencyu0022 target=u0022_blanku0022u003edevelopmental delaysu003c/au003e and disabilities.