Weight gain is listed as a possible side effect of the Minivelle Patch, but it is typically described as mild and temporary. Menopausal hormone therapy or hormone replacement therapy, including the use of Minivelle patch, can cause fluid retention, which may lead to bloating or weight gain. However, it is important to note that individual experiences may vary, and not all individuals will experience weight gain while using Minivelle patch. If you have concerns about weight gain or any other side effects, it is recommended to discuss them with your healthcare provider. They can provide personalized advice and guidance based on your specific situation.