Regular vape juice and nicotine vape juice aren't far from each other when it comes to the difference between the two. Indeed, the experience you receive from both is significantly different, however. The difference between the two types of vape juice comes down to the type of nicotine that is used and the ratio of ingredients that are used. Regular vape juice uses free-base nicotine, while salt nicotine vape juice uses an altered version of nicotine that was created to lower the pH levels. This allows manufacturers to raise the nicotine strength while reducing the throat-hit (harshness). The ratio of ingredients is also different but the ingredients themselves are the same. Nicotine Salt vape juice will often feature a 50/50 blend, while regular vape juice is commonly 70/30 (VG/PG).