Botox injections don't require much preparation or downtime. The procedure is quick and carries very little risk. That said, because there is a slight chance that you could bruise after receiving injectable treatment, you may want to avoid blood thinners for a few days before your appointment. Blood thinners come in all types, not just prescription medications! Aspirin and ibuprofen can thin the blood. Supplements like Gingko Biloba and vitamin E may, as well. Finally, alcohol is a blood thinner, so you may choose to skip that cocktail or glass of wine in the days before receiving injectables.