The protein serum amyloid A, produced by the body in reaction to infection or inflammation, is known as AA (secondary) amyloidosis. In this condition, abnormal proteins accumulate in tissues and organs. These abnormal protein clumps are referred to as amyloid deposits. It is referred to as secondary due to its occurrence as a result of another illness or condition. Kidneys, spleen, and liver are commonly affected by secondary (AA) amyloidosis. However, it rarely affects the heart.