The main ingredient – tortilla chips are generally gluten-free as well as cheese and all other ingredients in this recipe. But always check information on the packaging to be sure. I like to use Doritos Cool Original Tortilla Chips. These don’t contain any gluten but be aware of cross-contamination from the factory if you are celiac. I also found out that some of the Doritos Tortilla chips flavours contain wheat – like Doritos Chilli Heatwave Tortilla Chips so choose carefully when picking ingredients for your Nachos.