While some face serums may contain ingredients that are safe for use on the lips, we don’t recommend applying Active Compound to your lips. The skin on the lips is thinner and more delicate than the skin on the face and prone to sensitivity and dryness. The active ingredients in a serum may be too strong for this area and lead to irritation such as flaking and redness. To play it safe, we recommend using a lip-specific product to address any concerns you may have on the lips.