One of the great things about Kybella is that it’s straightforward. No recovery time. You can go back to your normal routine right away. Basic over-the-counter pain relievers will help with any mild discomfort you might have post-procedure. Like any injection, there’s a chance you’ll have some minor bruising or temporary redness, but it’s easily covered by makeup and usually goes away quickly. Less common Kybella side effects can include: Nerve injury in the jaw (which can cause an uneven smile or facial muscle weakness) Trouble swallowing Injection site problems including: bruising, hair loss, open sores (ulcers), damage and tissue cell-death (necrosis) around the injection site. Call your provider if you develop open sores or drainage from the treatment area.