You might. Taking Xgeva can lead you to have hypocalcemia (low levels of calcium). And if you have hypocalcemia before you start taking Xgeva, the drug can lower your calcium levels even further.
To help prevent or treat low calcium levels, your doctor may prescribe calcium supplements if you’re taking Xgeva for:
multiple myeloma
bone metastasis from solid tumors
certain giant cell tumors
Along with the calcium supplements, your doctor may also prescribe vitamin D supplements. Vitamin D helps your bones absorb calcium.
While you’re taking Xgeva, it’s a good idea to know the symptoms of hypocalcemia. See the “Serious side effects” section above for a list of symptoms. Tell your doctor if you notice any of them while taking the drug.
And if you have questions about hypocalcemia during your Xgeva treatment, talk with your doctor.