The Pelger-Huët anomaly is a genetic abnormality that affects the shape of white blood cells, particularly neutrophils. Neutrophils are a type of white blood cell essential for the immune system's functioning. In dogs with this anomaly, their neutrophils appear less segmented and more rounded under a microscope. This anomaly is generally considered benign and does not impact the dog's health or overall well-being. Vets can diagnose it through blood tests, but it typically does not require treatment.