If your audit is related to an application for DEA registration, following its investigation, the DEA may issue an Order to Show Cause. This is a denial of your DEA registration application. If you receive an Order to Show cause, you will need to request a Show Cause Hearing. And if you receive an unfavorable determination at the hearing, you will need to file an appeal in order to preserve any opportunity to prescribe or dispense controlled substance medications as part of your practice.