Yes, absolutely! Diapers are specially designed to be safely worn by little newborn babies. Not only that it is also safe for newborns that are barely even a day old. However, there are a few diapers separately that are specifically made only for newborn babies keeping them secure. Irrespective of it all, make it a point to change the diapers worn by the newborns every two to three hours. It is important as keeping them on could lead to infections or rashes, causing irritation and discomfort to the babies.