An inverted microscope is a microscope with its transmitted light source and condenser above the stage pointing down, while the objectives and turret are below the stage pointing up. Open-frame inverted microscopes, like our IXplore Standard and IXplore Pro systems, are great solutions for labs looking to adapt and customize a system to their needs. The systems work with multimodal solutions, such as TIRF illuminators or spinning disk confocal modules, to offer flexible imaging options. When using open-frame inverted microscopes for fluorescence imaging, a dedicated darkroom is usually required to avoid interfering signals from room lights.
If there is not enough space for a dedicated darkroom, an enclosed, all-in-one fluorescence microscope, such as the APEXVIEW APX100 digital imaging system, is the best option. An all-in-one fluorescence microscope is an automated research microscope with a box frame that enables users to image under normal lighting conditions. Its automated workflow removes complex steps typically involved in setting up an advanced fluorescence or confocal system, and these compact and versatile microscopes can be placed almost anywhere in a lab or core facility.