Loperamide is a medication commonly used to treat diarrhoea. It usually starts to work within 1 hour of taking it and can help to make your symptoms better. While the exact timing may vary depending on the individual, in most cases, Loperamide provides fast relief by slowing down the movement of your gut and reducing the frequency and urgency of bowel movements. It is important to follow the instructions provided by your doctor or pharmacist and not exceed the recommended dosage to avoid any potential side effects.