If you are looking for products for sensitive skin, then Vanicream is better as it is free from a majority of the chemical irritants and toxic ingredients. It is a simple skin care brand with no frills and fancies. Cerave products are made with ingredients like hyaluronic acid and ceramides that tackle specific skin care issues. You can choose the products from either of these reputable brands, depending on your skin care needs, skin type, and reactivity.