The primary difference is that collagen is a protein while biotin is a vitamin. The body produces collagen on its own, while biotin has to be taken externally, either via food or as supplements. Ideally, there are no ‘vs’ between the two since both are important and play different crucial roles in the body.
Biotin facilitates metabolism to break down carbohydrates, protein, and fat and aids in better skin health, hair, and nails. On the other hand, collagen improves your bone density, cartilage, skin, and tendon. It also enhances the health of arteries, organs, and muscles.