This depends on how much work you want to put in for your cat's daily routine! The Siberian Forest Cat has undergone significant testing regarding its Fel d 1 levels, which are lower than the average. They are also easy cats to maintain, needing only occasional brushing. If you don't mind extra work, though, a Sphinx cat diffuses very little Fel d 1 and is perhaps the closest thing to a hypoallergenic cat, but requires a high level of skin care, including regular bathing, sun protection, and clothing for warmth.