I prefer to smoke my pork butt at 250 degrees. I find that this cooks the pork roast a bit quicker but still gives it a delicious texture. If you smoke at 225 degrees you can plan on 2 hours per pound of pork. If you smoke at 250 you can plan on about 90 minutes per pound. Either temperature is going to give you a very similar result, the lower temp just takes a bit longer.