There are chemicals on the market that can help get rid of mosquitoes, but their effectiveness is usually short-lived compared to the products that professional pest control providers have access to. Malathion and permethrin are two of the most popular products available at home and garden stores. These insecticides will work for a few days before breaking down and becoming ineffective. While malathion used in small amounts is not harmful, permethrin is known to be toxic to bees and fish.