PEOs (professional employer organizations) are designed specifically to help small- to mid-sized businesses. Typically, these businesses don’t have the resources in house to effectively manage benefits, payroll, Human Resources, HR compliance and workers’ compensation. A PEO fills that need and assumes the responsibility for routine, HR administration, such as payroll, employee handbook, safety assessments, and health benefits open enrollment. The business maintains complete control over the employees and day-to-day business operations.