With IUI, sperm is introduced into the womb by means of a small procedure at the time of the cycle when the woman is ovulating and then the egg is released naturally from the woman with the hope that the sperm and egg will meet and form an embryo. With IVF the person providing eggs has to take medication to grow several follicles, the eggs are removed from the body during an egg collection procedure and then fertilised with the sperm in the laboratory. The fertilised egg and sperm then form an embryo which is placed back into the womb a few days later. For a same-sex female couple where the lady has normal fertility levels and patent fallopian tubes it may be an option to try IUI first as it is less invasive and less expensive. ICSI is a specific method used in the laboratory to fertilise the eggs. Unlike standard IVF, where the sperm and eggs are mixed together to allow the sperm to fertilise the eggs, in ICSI an individual sperm is injected directly into each suitable egg. ICSI is recommended to patients based on their medical history and test results and would be discussed with you at your new consultation appointment with a doctor. PICSI is a very similar process to ICSI. There is an additional sperm election method which is used to choose sperm which are most likely to be mature. As with ICSI this is recommended based on your medical history and test results and will be discussed with you at your new consultation appointment with a doctor.