While it may not be possible to prevent ADEM completely, maintaining overall health and hygiene can reduce the risk of infections that may trigger the condition. Staying up-to-date with vaccinations is also important, as some vaccinations have been linked to ADEM. However, it's essential to remember that the benefits of vaccinations in preventing serious infectious diseases far outweigh the minimal risk of ADEM. Consulting with healthcare providers about individual vaccination decisions is recommended.