If you’re applying to multiple graduate school programs, you should tailor your personal statement to each application.
Some applications provide a prompt or question. In this case, you might have to write a new personal statement from scratch: the most important task is to respond to what you have been asked.
If there’s no prompt or guidelines, you can re-use the same idea for your personal statement – but change the details wherever relevant, making sure to emphasize why you’re applying to this specific program.
If the application also includes other essays, such as a statement of purpose, you might have to revise your personal statement to avoid repeating the same information.