The number and distribution of fat cells is believed to be determined at an early age as a manifestation of genetics. With adult weight gain, there are not more fat cells, but rather the cells expand. Also, fat cells in different parts of the body respond differently to diet, exercise, and hormonal changes. That is why the usual liposuction patient has discrete problem areas such as the outer thighs that are out of proportion to the rest of the body. Liposuction does remove cells, permanently reducing the fat “storage capacity” in specific areas. Normally, this results in more even distribution of body fat.