If you're taking oral steroids, you may begin to feel better within a week, but it might take up to a month. If you're taking rectal steroids, you should feel better in a week or two. The full effect of the steroid will not be felt for several weeks though. Ulcerative colitis is a chronic condition that affects the large intestine and colon. It is characterized by inflammation, injury, and irritation to the lining of the colon. This disease can cause severe diarrhea, abdominal pain, blood in the stool, and anemia due to low red blood cell production by the bone marrow. There are various treatments available for ulcerative colitis; however, there is no cure yet. Medications used to treat the disease include hormones, immunosuppressants, anti-inflammatory agents, and probiotics. Hormones used to treat ulcerative colitis include salicylates, sulfasalazine, and mercaptopurine. Hormonal therapies work by reducing inflammation and immune response. They may be used alone or in combination with other medications. Immunosuppressants are drugs that reduce the body's ability to fight off infections and cancer cells. These drugs work by blocking the action of enzymes needed for lymphocytes (cells that protect the body against viruses and bacteria) to function properly.