Check with your doctor to see if more BOTOX could help. If adding a bit more BOTOX is not going to get rid of the lines and give you your desired results, a combination approach may be necessary. Mild wrinkles may smooth out after a single session, but deeper wrinkles can take more time (and more product) to improve. If the lines you are still seeing are there at rest on your face without making facial expression to see them, they may need some dermal filler added to the lines after the BOTOX treatment has kicked in. Anti-aging treatments are a process, and sometimes a combination approach delivers the best results.