The deficiency of vitamin C results in a rare disease called Scurvy. The symptoms are anaemia, exhaustion, and spontaneous bleeding, debility, pain in limbs, and swelling in some parts of the body. Scurvy occurs when plasma concentration falls below 0.2 mg/dL. It can be treated with oral or intravenous Vitamin C supplements. Other diseases of vitamin C deficiency include gum disease and connective tissue problems.