This NOFO is not limited to any particular pathogens of public health concern. Work of the network is intended to meet the needs of public health and to align with the strategic direction of CDC programs, and to incorporate new technologies and approaches from the rapidly evolving field of genomics. Therefore, the network and individual PGCoEs are expected to be agile and flexible in identifying, implementing, and amending specific activities, to the extent consistent with the terms of this cooperative agreement. Annually, by way of the PGCoE cooperative agreement continuation planning and process, projects will be evaluated and amended as necessary in light of public health priorities, advancement in the field and emerging issues and infectious threats. Added April 12, 2022