Yes, there is a difference when washing linen fabric and linen blend fabrics. Linen blends are typically made of other materials like cotton or synthetic fibers, so different care instructions should be followed to ensure the garment lasts longer.
Hand-washing with mild detergent in lukewarm water is usually best for both types of fabric. However, the drying process may vary depending on the blend percentage; air drying flat is often recommended for delicate pieces.