Chrome is able to play MKV video formats natively on most operating systems, including Windows, macOS, and Linux. This means that you should be able to play MKV files in Chrome without the need for any additional software or plugins.
However, there are some cases in which Chrome may not be able to play MKV files. For example, if the video is encoded with a codec that Chrome does not support, or if the file is corrupted, Chrome will not be able to play the video.