First things first - when you're vacuum sealing, make sure to leave enough room in the bag (about four inches from the top) so that everything goes smoothly, otherwise your food may not stay fresh the way it should. And while this may seem obvious to some, remember that vacuum-sealed food still needs to be refrigerated. The seal will only preserve your food in the conditions in which it's supposed to be stored. Finally, if you need to thaw your sealed food, make sure to remove it from the vacuum-sealed bag first, or you may wind up getting food poisoning caused by the bacteria clostridium botulinum, and I don't think I need to say that we definitely want to avoid that.