If bothersome menopause symptoms like hot flashes, night sweats, and vaginal changes persist despite making lifestyle modifications, hormone therapy may help provide relief. Systemic hormone therapy with estrogen alone or estrogen plus progestin is highly effective for treating these symptoms. Speak to your healthcare provider about whether hormone therapy is appropriate for you based on your medical history and risk factors. Localized vaginal estrogen is another option that treats genitourinary symptoms effectively.