Platelet-rich fibrin (PRF) is a second-generation form of platelet-rich plasma (PRP), which is concentrated growth factors from the blood used to stimulate new blood vessel (angiogenesis) and hair growth by signaling the hair follicle to enter into the growth phase. PRF contains no additives and is made by collecting a small amount of the patient’s own blood, which is prepared in a centrifuge. Growth factors and leukocytes are extracted from the blood and injected into the treatment area. The area is then microneedled using the FDA -cleared RejuvaPen NXT to enhance delivery of PRF to the hair follicles.