It is not as tricky as it may seem. Follow the steps:
Open one of the best Skrill betting sites from this article;
Sign up here;
Log in;
Click or tap Esports in the site's menu;
Choose one of them as well as an interesting event;
Click or tap the odds for one of the outcomes of this event;
Enter the sum of a deposit;
Deposit this amount;
Confirm the stake.