Fatigue is one of the symptoms of PVCs. Breathing difficulty Feeling dizzy or lightheaded. These problems are more common as you get older. You may also experience pain in your chest, neck, back, or arms. This can be caused by irregular heartbeat or increased blood pressure. If you are having severe pain and feel like you might have a heart attack, call 911 or go to the emergency room immediately. PVCs can be serious if not treated properly. Therefore, it's important to see your doctor if you experience any of these symptoms. He or she can check your pulse and perform other tests to determine the cause of your fatigue.