You can still take other supplements alongside Paratrex at the same or 20-30 minutes away from each other; either method works. Paratrex helps eliminate harmful organisms transmitted by people, pets, the environment, food, and water. It is not for fungal overgrowth specifically. We recommend using Mycozil as a natural yeast and fungal cleanser. Here you have more details: https://globalhealing.com/products/mycozil. If you prefer, you can take Paratrex and Mycozil on the same day for added support.