It takes multiple attempts at quitting before many smokers become lifelong nonsmokers. You may be successful on your first try, but if you aren't, don't give up. Cigarettes hook smokers in three powerful interlocking ways, each of which needs to be addressed when you are trying to quit:physical addictionhabitemotional dependenceIf you feel you need help to quit, talk to your health care professional about nicotine replacement therapies or buproprian (Zyban) or varenicline (Chantix).