One common issue is a faulty cable connection. Ensure that the Thunderbolt cable and adapters are securely connected. If you suspect the cables are the culprit, try using a different cable or adapter. Reseating the GPU in the eGPU box can also resolve detection issues. Disconnect the video card from the PCIe socket in the eGPU box and disconnect and reconnect the video card's power connector. Additionally, restarting the system and performing a hard reset of the eGPU unit may help resolve detection problems.