Single coil pickups generally have a bright, clear, and crisp sound reminiscent of that classic Strat tone. They may also produce some noticeable hum or noise, especially when played with distortion or high gain. On the other hand, humbuckers have a thicker, warmer tonality with a more pronounced midrange and less noise due to their noise-canceling design. Pre-wired pickguards come in different configurations, featuring single coil pickups, humbuckers, or a combination of both, allowing guitarists to choose the best fit for their playing style.