The proper dosage of anakinra will vary between patients and is based on several factors. You should always follow your doctor’s instructions or the directions on the label. The information below refers to typical doses of anakinra. If these doses are not consistent with your prescription, follow your prescription. In most cases, anakinra will be prescribed at 100mg per day. This is conveniently the same dosage as the prefilled syringes that the drug comes in. However, for some other conditions that the drug may be used to treat, other than rheumatoid arthritis, the dosage may be based on the patient’s weight. People with severe kidney disease may be prescribed 100 mg every other day.