The common causes of upper gastrointestinal bleeding are: liver cirrhosis leads to the rupture of the varicose network of the fundus of the esophagus and the fundus of the stomach, leading to the upper gastrointestinal bleeding. Peptic ulcer is also one of the common causes of massive upper gastrointestinal bleeding. There is also acute gastric mucosal damage. Such as drinking, poisoning, etc. Stress gastric ulcers caused by brain injury can also induce acute upper gastrointestinal bleeding, and leukemia can also be caused.