We are not guessing, since none of us has any experience in dermatology. The material itself is soft and smooth, but for instance one (1) customer suffering from eczema found that the material was not suitable for them.If you have bad experiences of synthetic fibres on your own skin or suspect that it might worsen the irritation of your skin, it is perhaps better not to try.We are sorry that we don’t have a more rational answer to this question. The product and the material as such don’t contain any chemicals that would irritate the skin.