Sculptra is formulated from poly-L-lactic acid, a synthetic substance that is biodegradable and biocompatible. Like dermal fillers, Sculptra is administered via a series of injections using a very thin needle. Sculptra injections contain thousands of microparticles and immediately plump your skin in much the same way as dermal fillers. Once in place, however, Sculptra actually stimulates your body to produce its own collagen strands.