Generally, 8 thighs takes 50-55 minutes in a 350°F oven, but it also depends upon a few factors: Temperature of oven Type of poultry: skin-on takes a little longer than skinless Number of thighs (8-10 thighs take longer than 2-3) As ovens vary, the best way to determine the doneness of poultry is to use a reliable meat thermometer. When the internal temperature reaches 165°F, it's done!