It’s possible to use a cash-out refinance on your home to buy an investment property. You could use the withdrawn money to make a down payment or buy the investment property with cash. And you can do this as soon as the refinance closes. However, you still have to meet your lender’s minimum credit score requirements for refinancing. And you’ll likely need a fair amount of equity in your current home, as lenders usually require15 to 25 percent down to purchase an investment property.