While you can use retinoids with other ingredients and skin care products, we recommend avoiding simultaneous use with the CLEAR Daily Skin-Clearing Treatments, containing benzoyl peroxide, as this ingredient can diminish the retinaldehyde's efficacy. Outside of this recommendation, you can use this retinaldehyde treatment with other skin care ingredients such as AHA, BHA, vitamin C, niacinamide and more. Be sure to consult your prescribing physician or health care provider if you’re currently using a prescription topical or oral retinoid product.