Since multiple cases of melanoma appearing initially as regional metastases (eg, cutaneous or lymph node) in the presence of full remission of the primary melanoma or an unknown underlying tumor have been documented,8, 9, 10, 11, 12 suggesting a link between The overall 5-year survival rate for all melanoma patients is 92 percent. This indicates that 92 out of every 100 persons diagnosed with melanoma will live for another five years. The 5-year survival rate is 99 percent in the very early stages. When melanoma spreads to the lymph nodes, the 5-year survival rate is 63%.