IGRT is often used for tumors located close to sensitive structures and organs in the body. It’s also useful for tumors that are likely to move during treatment or between treatments, such as lung tumors, which can be affected by breathing. IGRT is used at MSK most often to treat lung cancer, breast cancer, prostate cancer, brain cancer, spine cancer, bladder cancer, esophageal cancer, liver cancer, and bone cancer, as well as for lymphoma.