Yes, you can take a weed vape on a plane. However, there are some things to keep in mind. First, most airlines will not allow you to bring any kind of open flame onboard the aircraft. This means that you'll need to make sure your vape is fully charged and ready to go before boarding. Second, while cannabis is legal in some states, it is still illegal under federal law. This means that if you're flying into or out of a state where cannabis is not legal, you could face federal charges for possession. Finally, keep in mind that TSA agents are not looking for drugs - they're looking for weapons and explosives. So if they do happen to find your weed vape, don't expect them to be too understanding.