The house edge varies, depending on the specific rules and variations of the game, as well as the number of spots chosen by the player. In general, keno has a relatively high house edge compared to other casino games. The house edge typically ranges from about 20% to 30%, so it’s a game where the odds are less favorable for the player. Be careful of the house edge when playing, because in the long run, the majority of wagers will go to the casino.