However, tuberculosis germs may infect any region of the body, including the kidney, spine, and brain. If not treated appropriately, tuberculosis (TB) can be lethal. The main way that TB affects the body is through its reaction with our immune system. The most common symptom of exposure to M. tuberculosis is a fever and a general feeling of illness. This is followed by a period when many people do not show any symptoms at all. If infected with TB bacteria, some people will develop active disease while others will maintain their resistance to the infection. Those who develop active disease display various symptoms depending on which part of the body is affected. For example, someone might have trouble breathing with chest pain, weight loss, or night sweats. A physician will be able to diagnose tuberculosis (TB) based on these symptoms and how long they have been present. There are different types of treatments for tuberculosis (TB). Drugs are often used to kill the bacteria when it is found in areas of the body not vital to survival such as the bones or nervous system. Drugs are also used to prevent the spread of the infection if patients are not yet sick. Some examples of drugs used to treat tuberculosis include isoniazid, rifampin, pyrazinamide, and ethambutol.