The doctor should recommend the patient to visit another doctor, also for the reason that the truth of the finding is verified. The traditional rule applies here: " measure twice, cut once". In addition to ultrasound and nuchal translucency, or cervical clearance, samples of alpha-fetoproteins in the amniotic fluid are taken from the pregnant woman in the 16th week, while all these examinations form a single unit called integrated screening. Based on the results and degree of suspicion, the patient will then be offered amniocentesis, i.e. the collection of amniotic fluid. However, this procedure is considered a major intervention in the pregnant woman's body and can be dangerous for her and the fetus. Therefore, the patient can refuse it. The results can also be unclear, and therefore in the so-called gray zone, which means that it is necessary for a pregnant woman in the 20th week of pregnancy to undergo a more detailed examination.\r