The reality is that no formula can completely mimic human breast milk. However, scientific and nutritional advances have come a long way in recent years, and there are some great options. Any of the formulas on our list should meet your baby's nutritional needs for the first year of life, providing they don't have a special medical condition.
The formula most structurally similar to human breast milk is Similac 360 Total Care. This formula contains an unprecedented 5 HMOs, which are prebiotics found in breast milk that should help babies digest and absorb nutrients. It also contains DHA (which is found in varying amounts in human milk), ARA, carbs, fats, and vitamins that are meant to mimic those found in breast milk. This formula also contains cow's milk proteins that are not hydrolyzed, so they are still quite a bit larger than the proteins found in human milk.