Your doctor at Access Health Center gives you the first pill, mifepristone, during your first appointment. This medication blocks your body’s own progesterone, a hormone required for pregnancy to progress normally. During this visit, you are also given antibiotics. You take the second pill, misoprostol, 24 to 48 hours later. This usually can be done at home. Misoprostol causes cramping and bleeding to empty your uterus. As the process takes place, you have a really heavy, crampy period that’s similar to what you’d experience during an early miscarriage.