Exotic cats exhibit significantly different behaviors compared to domestic cats, largely due to their wild nature and genetic predispositions. Unlike domestic cats that might adapt well to indoor environments and human interaction, exotic cats often display more complex and instinctual behaviors. They may not respond to training or handling in the same way and can resist confinement. Challenges include their reluctance to use litter boxes and a general disinterest in obeying commands, traits that can make them less suited to typical pet living conditions.