Dendritic cells can interact with both B cells and T cells in different regions of the lymph node. B cells are primarily found in the follicles of the lymph node, which are located in the outer cortex. Dendritic cells can be found in the interfollicular regions and the T cell zones surrounding the follicles. T cells are primarily found in the paracortex of the lymph node, which is located between the cortex and the medulla. Dendritic cells are also present in the paracortex and can interact with T cells to initiate and coordinate the adaptive immune response. Overall, dendritic cells can be found in various regions of the lymph node and can interact with both B cells and T cells to initiate and coordinate the immune response against invading pathogens.