Januvia is a dipeptidyl peptidase-4 (DPP-4) blocker.
DPP-4 is a protein that blocks the action of incretin hormones. Incretins help control your body’s blood sugar levels. When you eat a meal, your digestive tract releases incretins. They affect your pancreas, stimulating it to make and release insulin. And insulin lowers your blood sugar levels.
By blocking DPP-4, more incretin hormones are available to help control your blood sugar level. This is Januvia’s mechanism of action.