B, C, D, & E. Breast cancer patients should be counseled that intensive surveillance using laboratory and imaging tests does not improve overall survival or quality of life. However, monthly breast self-examination, annual mammography of preserved breast tissue, and a careful history and physical examination every 6 months for 5 years are recommended (SOR C). A Cochrane review, based on two randomized, controlled trials, found that less-intensive follow-up strategies based on periodic clinical examinations and annual mammography seem as effective as more-intense surveillance schemes. Any positive findings on the history and physical examination would certainly warrant further investigation. Female Hodgkin’s disease survivors treated with chest irradiation are at increased risk of developing breast cancer; surveillance should be started at 25 years of age (SOR C). The U.S. Preventive Services Task Force recommends routine screening for depression all adult patients, but only if staff-assisted depression care supports are in place to ensure accurate diagnosis, effective treatment, and follow-up care (USPSTF B recommendation). Survivors of childhood cancers are at increased risk for depression, and should be screened and treated as appropriate (SOR C). Use of carcinoembryonic antigen testing and CT for follow-up of colorectal cancer patients yields a survival advantage of about 19% (SOR A). However, there is insufficient evidence to support any optimal combination of tests or frequency of clinical follow-up. Expert recommendations suggest that prostate cancer survivors should receive annual digital rectal examinations, plus monitoring of prostate-specific antigen levels every 6 months for 5 years, and then annually (SOR C). More test answers on https://studyhippo.com/abfm-preventive-medicine/