CBT is created within the trichomes of the cannabis, hemp flowers, or calyxes, the female part of the hemp plants. The trichomes, which are rich in cannabinoids, are then separated and extracted using various scientific methods, including ethanol and supercritical CO2 extraction.
Chromatography machines are used to separate and isolate the individual molecular compounds extracted from the plant, including CBT and CBT-C. The CBT extraction method requires solvents due to the low amounts of cannabinoids found in the hemp plant.