Restylane products are contraindicated in certain populations. Based on clinical studies and research, it is advised to avoid using Restylane products in pregnant or breastfeeding individuals and those under the age of 22. Additionally, individuals who have taken blood-thinning medications or who have clotting issues should avoid using Restylane products. Those with a severe allergy history, especially to gram-positive bacteria or drugs that have required hospital treatment, should also avoid the product. Individuals with known lidocaine allergies should not use Restylane products containing lidocaine, such as Restylane-L, Restylane Lyft, Restylane Silk, Restylane Kysse, Restylane Refyne, Restylane Defyne, and Restylane Contour. Restylane is the only product that does not contain lidocaine. As with any medical procedure, it is essential to consult with a healthcare provider to determine if using Restylane products is suitable for you.