Mirabegron has also been shown to exert protective effect against heart failure:
Studies suggest that beta-3-adrenergic-receptors such as mirabegron offer a protective mechanisms under conditions of increased stress to the heart muscle.
In mice, mirabegron reduced the incidence of heart enlargement.
In patients with reduced blood flow to the heart, mirabegron significantly increased blood circulation in the left ventricle of the heart.