In trials, PYODERM S was shown to have equivalent activity to a shampoo containing 2%chlorhexidiine and 2% miconazole against malassezia. In this specific formulation and at a concentration of 3% chlorhexidine has been shown to have good activity against malassezia. In vitro Malassezia counts were much reduced after 2 and 4 minutes of exposure and no organisms survived for 8 minutes, demonstrating the rapid antibacterial and antifungal activity of PYODERM S.