The 4 main differences between national and regional political parties in India are
A national party has influence all over the country or in many states of India. The influence of a state party is in a state or a few regions.
National parties care for national interests, whereas regional parties promote mainly regional interests.
Regional parties stand for greater autonomy for the states. The national parties, on the other hand, have to harmonise various conflicting regional interests. They try to end regional imbalances.
An exclusive symbol (such as lotus for B.J.P. and hand for LN.C.) is reserved for a national party throughout India. But in the case of a regional party, a symbol for it is reserved for it in the state in which it is recognised.