Some research suggests an association between nutrient deficiencies and different manifestations of anxiety. For example, zinc deficiency may have a relationship to panic disorder and OCD. Other deficiencies that may contribute to anxiety are magnesium and vitamins D, B6, and B12. Your doctor will likely order a blood test if a deficiency is suspected. Ongoing research seeks to determine whether vitamin E, omega 3 polyunsaturated fatty acids, glycine, and inositol supplements could have protective or other anti-anxiety benefits.