The maximum recommended carboplatin dose is calculated with a GFR estimate capped to 125 ml/min for patients with normal renal function. To compute the maximum dose your patient can receive, use the equation:
Maximum carboplatin dose (mg) = AUC * (125 ml/min + 25)
Maximum carboplatin dose (mg) = AUC * 150
As you can see, the maximum dose depends mostly on the target AUC.
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