After taking Suboxone, the effects can last for up to three days. The half-life of buprenorphine is 24 to 42 hours, which refers to the length of time it takes for your body to eliminate 50% of the substance. With that being said, Suboxone can be detected in your urine up to two weeks after taking it, as it typically takes five half-lives for a substance like Suboxone to leave your system altogether. If you have further questions for our Suboxone doctors at MedSave Clinic, we would be happy to answer them for you! We also welcome you to schedule an appointment on our website or give us a call. You can find our clinic at 246 E Campus View Blvd in Columbus, Ohio. We serve patients from Columbus OH, Clintonville OH, Northwest Columbus OH, Worthington OH, Orange OH, and Harlem OH.