There isn’t a set test for histamine intolerance. Skin prick tests only test for a histamine reaction to a specific allergen, not a consistent build up of histamine. One way to test for histamine intolerance is by following a low histamine diet for at least thirty days, then slowly reintroduce high-histamine foods and monitor your symptoms. If your symptoms reduce or disappear on a low-histamine diet but reappear after incorporating high-histamine foods, you likely have histamine intolerance.