If a bacterial infection is causing your blepharitis, you may need to take topical antibiotics for 2 to 8 weeks at a time. Chronic blepharitis is a health condition that usually responds promptly to appropriate treatments. Following preventive measures may help you manage symptoms. If you stop following these measures, blepharitis may return. If symptoms worsen, or if they don’t improve despite home treatments, you should consider reaching out to a doctor.