There is no definitive answer to this question, as it largely depends on the type of phone case that you are looking to create. If you are looking to create a phone case made from fabric, then it is definitely possible to do so with an iron. However, if you are looking for a more rigid or plastic-based phone case, then it is likely not possible to create it with an iron. Instead, you will likely need to use a different type of tool or machine in order to get the desired results. As such, it is best to consult with a professional if you are unsure about how to create the specific type of phone case that you are looking for.