You sure can make pumpkin crumb muffins! Fill the liners about 2/3 the way full (I like to use a large cookie scoop). Then add about 1 Tablespoon of the crumb topping to each muffin. Bake the muffins at 375°F for about 18 to 20 minutes, or until a toothpick inserted into the center comes out clean. Be careful not to brown the tops too much. Makes about 16 muffins.