Phendimetrazine is a weight loss medication prescribed by doctors to assist patients in curbing their cravings, especially at night. It can be beneficial in the early stages of the weight loss journey when combined with a healthy diet and exercise regimen. Phendimetrazine is FDA-approved, just like Phentermine, but some patients may find it easier to tolerate. It may be ideal for those battling weight-related medical concerns, such as diabetes, hypertension, and high cholesterol.