Yes, adaptogenic mushrooms can potentially interact with certain medications. Some mushrooms may enhance or weaken the effects of drugs, including blood thinners, diabetes medication, and immunosuppressive drugs.
For instance, Reishi mushroom is known to interfere with blood clotting potentially, so it might interact with anticoagulants or antiplatelet drugs. Therefore, it's essential to consult with a healthcare provider before starting any new supplement regimen, including adaptogenic mushrooms, especially if you take any medication. Your healthcare provider can advise based on your health situation and current medications.