Yes, Ivermectin is safe if taken as directed by the doctor inappropriate dose. Ivermectin is FDA approved for treatments of onchocerciasis and strongyloidiasis( these are two conditions of parasitic intestinal worms). For external skin conditions like rosacea, it is approved for topical use. It is not safe for breastfeeding and pregnant women; hence should be avoided. It is also not safe for children  having weight  less than 15 kg.