This all depends on your vaping habits and vape device. A bottle of SKE Crystal Salts contains 10ml of e liquid and a normal sized refillable vape tank or pod is 2ml, so that would give you 5 full pod/tank refills to a bottle. One 2ml pod/tank aims to deliver up to 600 puffs (at least 1 full day for an average vaper) so one bottle could last you upto 5 days!