Treatment for scabies includes anti-itch lotions, ointments, powders, shampoos, and pills. There are two types of medications used to treat scabies: topical and oral. Topical treatments are easy to apply and very effective in killing scabies mites immediately. They must be applied every day until the treatment is completed. Oral medications can be used along with a topical treatment or by itself to kill scabies mites after they have been brought into the body through skin contact.