A 2008 study found that 8 out of 10 cancer doctors surveyed had prescribed drugs off-label. It’s also common in pediatrics and HIV/AIDS care. Beta blockers are another example of off-label prescribing. They are FDA-approved for the treatment of high blood pressure, but are also used for patients with heart failure. Some beta blockers are now formally approved to treat heart failure, and it’s anticipated that some of these drugs used off-label will eventually get approved by the FDA for that use.