That is solely determined between patient and caregiver, but pellets are known to have been used worldwide to help those with opioid use disorder.  Naltrexone is FDA approved for the treatment of opioid use disorder in oral and injectable forms.  Patients must detox and be completely off all opioids for 7-10 days or longer in some cases prior to beginning any naltrexone therapy.  If successfully detoxed of opioids, the patient might then possibly be a candidate for naltrexone therapy if prescribe by a treating physician under his/her discretion.  It must be understood that, in addition to diminishing some of the urge to use, naltrexone may altogether block the euphoric effect of any opioid depending on the levels of naltrexone in the body. The treating physician should educate the patient and family about the potential consequences, including fatal overdose, should the patient use too much alcohol or opioids in an attempt to override the naltrexone blockade or once the naltrexone pellet has dissolved to a point where it releases non-effective quantities of naltrexone into the body.