If our understanding is correct, after the interactions described above, psilocin is then further broken down (metabolized) by monoamine oxidase (another enzyme) into O-Glucoronide and 4-Hydroxy-indoline-3-acetaldehyde, and the latter again into 4-Hydroxy-indole-3-acetic acid and 3-Hydroxytryptophole.
The whole process, the psychedelic experience, lasts anywhere from 4 to 8 hours (with psilocybin). This is highly dependent on a variety of factors. The first is the dosage, the more someone takes, the longer (and heavier) the effects may be. The amount of psilocybin (and psilocin) per mushroom (variety and/or batch) may of course also differ widely.
Based on a study with 18 volunteers the duration of the psychedelic experience was generally over at the 7-hour mark. The most measurable bodily effects (e.g. blood pressure) were seen after two hours. The biggest drug effects (e.g. joy/intense happiness and overall drug effect) were seen after three hours.