Medical News Today discussed the study’s findings with Heather Sandison, doctor in naturopathy, specialized in brain health. She was not involved in the study.
MNT asked Sandison how gluten triggers inflammation through the gut microbiome. She responded: “Gluten ingestion can trigger the production of zonulin, which can create a 'leaky gut' with gaps between cells where large molecules can cross from the gut into the bloodstream triggering a body-wide inflammatory response.”
Dr. Sandison also mentioned a theory that gut microbiota and gut-derived bacterial toxins called lipopolysaccharides may enter the bloodstream. Consequently, an “inflammatory cascade” ensues.
A 2022 study published in the International Journal of Molecular Sciences covered this theory.