In Honolulu, defenses against drug trafficking charges can include challenging the evidence's legality, arguing for entrapment if law enforcement induced the crime, or proving a lack of intent to traffic drugs. Each case is unique, and a defense strategy is tailored to the specific circumstances surrounding the arrest and charges. It's crucial to consult with a defense attorney who understands the complexities of drug-related offenses and can navigate the legal system to advocate effectively on your behalf.