Once you see the beginning of the appearance of wrinkles in those fine lines, it is the right time to start your treatments. This could occur as early as the mid-twenties, or earlier for some who have a genetic factor and a propensity for the skin to wrinkle at an early age. As this product has been on the market for many years, there are thousands of patients who have had consistent treatments for many years – and are enjoying the fact that they have fewer wrinkles and creases than others their age.