I'll tell you how to succeed in your attempts to flirt with Syanna. A strange relationship, but no judgment here. In Blood & Wine, you only have one romantic option to take to the end during the main story missions. Unfortunately, you will not have the chance to get it once we have reached a certain point in the story, so if you want to have a romance and sex with Syanna, listen up. • Choose Damien's route First, you must choose Damien's route during the mission Night of the Long Fangs. You can't have an affair with Syanna if you choose Orianna's route. • Be nice to her during the story You don't need to do anything for things to end up in bed. It would help if you simply chose polite answers while talking to her. You won't have the option to get intimate with her later on, so this is your only chance.