The answer is yes and no both. Some bicycle chains can be universal while others are strictly not. For example, road and mountain bike chains are different in terms of length and width. Overall, the chain components can be complex structures but products with universal acceptance is still possible. For example, a bicycle’s chain, cassette, shifters, and derailleurs, all can be of a different brand. And it can still work just like any other bicycle chain. When in doubt, you can always consult an expert or professional mechanic.