To convert 35mm negatives to digital images, it is best to use a dedicated negative scanner. Care should be taken to avoid fingerprints and dust on the negatives before scanning. If using a lower-end scanner, additional time may be required for color correction and retouching using software like Photoshop. Alternatively, individuals with a large quantity of negatives may consider hiring a professional film digitizing company like ScanCafe to ensure high-quality results.