For the best results and shoe longevity, try using warm water, dish soap, and a rag for spot cleaning—it’s best to avoid over soaking them in a washing machine. If you have stubborn stains or dirt, opt for an old toothbrush to scrub mud or debris away. To dry, stuff newspaper inside your running shoes and position them in front of a fan or allow them to air dry—it’s best to avoid putting your shoes in a dryer.