It’s not recommended to take Fem21 whilst using synthetic contraceptives as it can increase the excretion and metabolism of toxic as well as synthetic oestrogen.  As Fem21 works to rebalance your hormones and support the healthy functioning of the ovaries and formation of the endometrial lining, it may decrease the contraceptive effect of the pill, depo, implants (including the vaginal ring and the rod). Fem21 is safe to use in conjunction with IUD’s (intra uterine devices).  It may also be of benefit to have a 3 month break off the pill and have a reset / hormonal cleanse with Fem21, you can then resume the pill when you’re ready.