34 Delta flights head to San Francisco on average each week. Most will be flying from Atlanta Hartsfield-Jackson to San Francisco, the most popular route that Delta operates to San Francisco. Prices vary based on when and where you fly from - the cheapest Delta flight to San Francisco found in the past 3 days on momondo was €439, departing from Dublin. Delta is the most popular choice on momondo for this route and has been scored 8.0/10 by 9,010 of our users.