For cooking a chuck roast in an Instant Pot, a natural release is generally recommended. Natural release involves allowing the pressure to decrease on its own over a period of time after the cooking cycle completes. This gradual release helps prevent the meat fibers from contracting suddenly, which can lead to a more tender result. After a natural release of about 10-15 minutes, you can then use a quick release if needed to release any remaining pressure. This method tends to yield a more tender and flavorful chuck roast compared to using a quick release immediately after cooking.