Dermal fillers are not meant to last forever. Depending on the type of filler used, as well as its placement, the results of a treatment can last between several months and 2 years. The ingredients in dermal fillers gradually break down and filter out of the body through normal metabolic processes. Sculptra Aesthetic, a dermal filler that uses poly-L lactic acid, comes with the added benefit of promoting collagen growth within the skin. Over time, the poly-L lactic acid is flushed out of the body while the new, natural collagen stays behind.