There are some reversal agents for anticoagulants: Idarucizumab (reversal for dabigatran) & and Andexanet (reversal for apixaban (Eliquis), rivaroxaban (Xarelto), and (off-label) enoxaparin (Lovenox, and generics) in patients with active major bleeding. These are rarely used except for major life-threatening bleeds involving the brain or GI tract.