All dogs can get all dog diseases. That said, labradors generally have phenomenal appetites and are known to be prone to becoming overweight or obese. This is the most common disease you need to be aware of, and it can not only shorten their lifespan but also make other diseases worse. Labradors are also one of the most frequently studied dogs in research, so there are a long list of issues that have been studied in this breed (as opposed to other breeds where we have less information). Some conditions that labradors are predisposed to (based on research studies) include but are not limited to: allergies (which usually manifest as skin issues), some heart conditions, chronic hepatitis, diabetes mellitus, hypothyroidism, cranial cruciate ligament rupture, elbow and hip dysplasia, some muscle disorders, epilepsy, some kinds of cancer, juvenile onset cataracts, entropion, ectopic ureters, laryngeal paralysis, and low B12 levels ...aaaand swimming related conditions :) like attraction to water (no joke, there was a study about this -- it's hereditary in labs & they were shown to be more attracted to water than to humans or other dogs) and limber tail (sprained tail from swimming or wagging too much)