Saline infusion sonography is a minimally invasive procedure in that no injections or needles are required. Like other ultrasound procedures, SIS is extremely safe and no radiation is required.  With this type of scan, we can capture an excellent view of the uterus and endometrial lining in a relatively short amount of time, allowing us to see uterine abnormalities that may not be visible with transvaginal ultrasound and potentially preventing unnecessary surgery. SIS can also ensure that all fibroids and polyps are removed during surgery. Similar to other ultrasound procedures, SIS has no known harmful effects on humans.