While higher thread counts can indicate finer, softer fabric, it's not always a guarantee of better quality or comfort. Factors like fiber quality, weave, and finishing processes also play crucial roles. Moderate thread counts (300-400TC) often provide an excellent balance of comfort, durability, and value for hotels. Very high thread counts can sometimes result in heavier, less breathable sheets. The key is to balance thread count with overall fabric quality and guest comfort needs.