Yes, the change intervals for antifreeze can vary depending on the type used. Traditional ethylene glycol-based antifreeze typically requires changing every two to three years or 30,000 to 50,000 miles (48,000 to 80,000 kilometers). Extended-life antifreeze, such as propylene glycol-based or organic acid technology (OAT) antifreeze, may have longer change intervals, often around five years or 100,000 miles (160,000 kilometers). It’s important to consult your vehicle’s manual or the antifreeze manufacturer’s recommendations for the specific change interval.