It is normal to expect some amount of weight loss after breast reduction. This is especially so when the breasts are quite large and uncomfortable. That said, we expect the reduction of breast tissue usually removes between two and eight pounds of fatty and glandular tissue. Where this makes an enormous difference in appearance and physical comfort in the neck, shoulders, and back, it may not do much for the scale. Breast reduction is not a weight loss surgery. However, many women who have this procedure go on to lose 10, 20, or more pounds due to the increase in comfort that allows them to exercise as they would like.