In most cases, taking screenshots in safe mode or other restricted environments may not be possible. Safe mode is a diagnostic mode in which Windows operates with minimal drivers and services, and certain functionalities, including the ability to take screenshots, may be limited or disabled. While the built-in keyboard shortcuts for taking screenshots, such as PrtScn (Print Screen), may still technically work in safe mode, the functionality to capture and save the screenshot may be unavailable due to the restricted environment. Similarly, in other restricted environments or scenarios where certain system components or services are disabled, the ability to capture screenshots may be restricted or non-functional. It's important to note that the availability and functionality of screenshot tools or software may also be impacted in restricted environments, as they may rely on specific system components or services to function properly.