Results from your genetic tests will fall into one of three categories: Positive A mutation related to an inherited cancer has been found in at least one of your tested genes. A positive result confirms an increased risk for an inherited cancer. This information may be used to inform decisions you and your healthcare provider make about your medical care. A positive result also indicates there may be up to a 50/50 random chance that each of your children, brothers, sisters, and parents has this same mutation. This means, that like you, they are at increased risk to develop the cancer linked to your mutation and should consider genetic testing. Negative No cancer-linked genetic mutations were found in any of your tested genes. Since inherited disease risk(s) and management recommendations are based on personal and family history as well as genetics, you will want to discuss next steps with your healthcare provider. Despite your negative result, genetic testing may be advisable for family members depending on their health history. Variant of unknown significance At least one genetic mutation was found, but it is unclear if this mutation causes an increased risk for an inherited cancer. Your next steps should be determined by your personal and family history. As more genes are researched and additional testing becomes available, your results may change over time. This means that your variant of unknown significance could become known. It’s impossible to predict when this might happen though.