The decision to initiate or continue HRT post-menopause boils down to a risk-benefit analysis. The best choice may vary across individuals based on factors such as menopausal symptom severity, family history, and personal preferences. Dr. Attia maintains that hormone therapy has substantial positive impacts beyond menopausal symptom relief and that the alleged risks associated with HRT are not supported by evidence, lack clinical significance, or otherwise fail to outweigh the benefits to health and quality of life.