The beta-2-glycoprotein-1 IgG and IgM test is a blood test used to detect the presence of IgG and IgM antibodies that may indicate a past or present case of antiphospholipid syndrome. It involves standard blood work that tests the blood sample against potential allergens that may form specific antibodies. If IgG/IgM antibodies are present, it is highly likely that the patient is suffering from APS.