Most mammalian cells in culture can be categorized into three types based on their morphology:
Fibroblast-like: These cells are bipolar or multipolar with elongated shapes, which grow attached to a substrate.
Epithelial-like: They are polygonal in shape with more regular dimension. These cells grow attached to a substrate in discrete patches.
Lymphoblast-like: They are spherical in shape and usually grown in suspension without attaching to a surface.