In the compounding pharmacy industry, there are specific definitions, regulations, and licensure that differ between running a sterile compounding laboratory or facility versus a non-sterile compounding laboratory or facility.   Sterile compounding follows strict standards established by the United States Pharmacopeia (USP) General Chapter <797> and is used when there is a high risk of infection, as sterile compounded medications are typically intended to be used as injections, intravenous (IV) infusions, or ophthalmic sterile compounds for eye drops. Medications like these need to be carefully prepared in a separate sterile clean-room, an environment free from viruses, bacteria, or any other infectious microorganisms.   PenCol Specialty Pharmacy offers a select catalog of sterile compounds that have undergone the required method suitability and container closure testing. We specialize in bimix, trimix, and quadmix for erectile dysfunction, atropine eye drops, and methylcobalamin (Vitamin B) injections.   Non-sterile compounding is more common and while these drugs are not prepared in a sterile clean-room, they are made with high standards and strict guidelines as established by the United States Pharmacopeia (USP) General Chapter <795>. Non-sterile compounding utilizes a clean environment where equipment, surfaces and materials are sanitized. Non-sterile compound medications include the production of solutions, suspensions, ointments, creams, gels, powders, suppositories, capsules, troches, dissolvable forms, and tablets, and are typically taken orally or used topically.