The duration of a game of Mosaic can vary depending on several factors such as the number of players and their familiarity with the rules. Generally, a typical game will last around 30-45 minutes. With experienced players who have mastered the mechanics of the game, it might be possible to complete a session within even shorter timeframes. However, when playing with beginners or taking more time for strategic planning during each turn, it is not uncommon for games to extend beyond an hour. Ultimately, playing time can be adjusted based on available time constraints or desired gaming experience.