While there are many medications that have potential interactions with flu shots, the vaccine's effect on the medications is generally minimal. However, depending on the medication you are using, your response to the vaccine may be slightly reduced. If you are concerned about any medication you are taking before getting a flu shot, check in with your doctor or a medical professional to know if there are any risks to getting the flu shot. Our medical professionals at Nova Patient Care would be happy to provide information on which medications could potentially interact with flu shots.