The platelets play a significant role in stopping the bleeding by secreting different factors that cause the Blood vessels to constrict and form a Blood clot. Platelets are a process called secondary homeostasis, which causes a fibrin clot to be formed. The platelets play a significant role in stopping the bleeding by secreting different factors that cause the Blood vessels to constrict and form a Blood clot. Platelet is a process called secondary homeostasis, which causes a fibrin clot to be formed. This is the final step in the mechanism of Blood Coagulation. The clotting cascade gives way to the development of fibrinogen, a soluble plasma protein that coagulates and forms a Blood clot. If the protein is composed of only platelets, then it is called white thrombosis, and if the red Blood cells are also present, they are termed red thrombosis. DVT takes place due to medical reasons or the lack of frequency in the body movements.