Well, that depends what you consider “downtown.” In most cities, “downtown” is regarded as the area of the city with office buildings, often in areas where people wear suits and work in jobs like tech and finance. Even in cities that generally aren’t known for that (such as San Diego), there’s still usually an area filled mostly with glass-and-cement buildings and restaurants and stores designed to support people who work roughly 9-to-5 hours.
But in New Orleans, “downtown” is a little different. Perhaps because the city is so old (founded in 1718), the part of New Orleans considered downtown are actually the neighborhoods near the waterfront. That includes the French Quarter, Treme, the Faubourg Marigny (next to the French Quarter), and the southern part of the Central Business District closest to the water (which blends with the Warehouse District). If you stay in those areas, you can walk to nearly all the main attractions in New Orleans Airbnbs in the French Quarter, too.
However, some people are starting to refer to the city’s entire Central Business District as “downtown.” That part of the city looks more like what people would consider an urban downtown area. It’s also where you’ll find the city’s convention center and the 74,000-person-capacity Superdome.