While consuming Premier Protein shakes in moderation is generally considered safe, it's essential to be mindful of their additives. Regularly drinking protein shakes, especially daily, can accumulate these additives in your system. This can result in gastrointestinal (GI) side effects such as bloating, constipation, diarrhea, gas, and stomach discomfort. It's advisable to listen to your body and adjust your consumption accordingly to avoid any pain or adverse effects.