A biologic is a medicinally large molecular product that is created from a living organism and contains proteins from living cells. In other words, it’s a product created from a living thing, on a molecular level. Because biologics are much larger and more complex than typical small-molecule drugs, the manufacturing processes are very complicated. In the United States, biologics are approved by the Food and Drug Administration (FDA), under a process distinct from new small-molecule drug approvals, or approvals for traditional medicines.