Yes, however, during the first days after the procedure, it is recommended to protect the affected area and avoid discomfort. If you received a PRP injection in your knee, ankle, or foot, you might need to use crutches. Starting with the second week, you will resume more and more physical activities, but you still need to avoid extreme effort or activities that cause pain. Following your doctor's recommendation will shorten the healing time, and the procedure will return better results.