Yes, the bottle dispensers are fully autoclavable at 121 C for 15-20 min at 15 psi. However, do not put the dispenser in the autoclave without disassembly. Disassemble the piston and shaft from the dispenser before autoclaving. The volume-adjustment knob must be kept in an unlocked position. Lastly, re-calibration is necessary after autoclaving. Please refer to the instruction manual for the correct detailed autoclaving procedure.