Barcelona’s best things to do are spread around the town, so there is no universal answer to this question. The nice areas to stay in Barcelona are Barri Gòtic, La Rambla, on the other side of Barri Gòtic is El Born, another maze of medieval streets with popular attractions of its own. Bordering the Old City to the northwest is Eixample, where you’ll find most of Barcelona’s striking Modernist buildings, including Gaudi’s Sagrada Familia, as well as the most upscale shopping. There are much more places to stay, so your choice where to stay in will make a difference in what you see and how you get there.