If you change the lifestyle behavior that led to obesity, you will not need to worry about those pockets of fat returning. The cells that were removed during liposuction are gone, and will never grow back. But if your weight begins to rise again, adjoining fat cells will expand to store the excess caloric intake. Therefore, it is possible to regain weight in the areas where liposuction was performed. Regular exercise and eating nutritious foods in limited quantities are the best ways to preserve your new shape.