Down’s syndrome is a chromosomal disorder. A person suffering from Down's syndrome shows the following symptoms: Short stature Small round head Furrowed tongue and partially open mouth Palm is broad with characteristic palm crease. Physical, psychomotor, and mental development is retarded in the person. This condition happens because of an extra copy of chromosome 21. As per various research reports, chances of having a child with Down’s syndrome increases with advancing maternal age because ova are present in females right from their birth. More is the age of the mother, cells will be older. Hence, chances of chromosomal non-disjunction will be more because of various Physico-chemical exposures during the mother’s lifetime.