Yes, sleep deprivation can affect your ability to remember information. When you don't get enough sleep, you feel fatigued and mentally foggy the next day. It makes it difficult to focus on tasks, and you may even make mistakes trying to recall important information. Sleep deprivation also reduces the brain production of neurochemicals responsible for memory formation. In other words, lack of sleep makes it harder for your brain to form new memories. So, in short, lack of sleep affects not just how well you think but also how well you remember things!