Magnesium, along with other electrolytes, plays an important role in blood pressure regulation. While some research studies have found magnesium supplementation to lower blood pressure, the evidence is inconclusive. In 2022, the FDA approved a health claim stating, “consuming a diet with adequate magnesium may reduce the risk of high blood pressure. However, the evidence is inconsistent and inconclusive.” More research is needed in this area before we can fully understand the effects of magnesium supplementation on the prevention of and treatment of cardiovascular disease, including hypertension. To manage and prevent high blood pressure, the American Heart Association recommends consuming a well-balanced, nutrient-dense diet that is low in sodium as well as maintaining a healthy weight, managing stress, engaging in regular physical activity, and reducing high-risk lifestyle behaviors like smoking and drinking.