Yes, you can play NBA 2k21 on gaming laptops you can play the game on any laptop that matches the system requirement and doesn't undergo thermal throttling. However, if your gaming laptop doesn't match the system requirements, the game won't run; even if it runs, the experience won't be worth it. You will see constant frame drops; the game will freeze and, sometimes, even crash. So, check the system requirements below and ensure your system is compatible.