There are a few signs of infection after having a tooth removed. If you experience any of these symptoms, contact your doctor or dentist as soon as possible. Bleeding more than 24 hours after extraction. Throbbing pain that isn’t relieved by pain medication. Extreme swelling of the face, jaw or gums. Oozing pus from the extraction site. Difficulty opening your mouth. Low-grade fever that persists or increases over time.