The odds of winning in Keno vary widely depending on the number of numbers you choose and how many of them match the drawn numbers. For example, if you choose one number, the odds of matching it are 1 in 4. If you select 10 numbers, the odds of hitting all 10 are approximately 1 in 8.9 million. Due to the high variance in odds, Keno is known for offering both small frequent wins and the potential for large payouts.