The shelf life of e-liquid depends on the ingredients used and how it is stored. Generally, e-liquid can last up to two years if stored in a cool, dark place away from direct sunlight. It is also important to keep your e-liquid away from heat sources, as this can cause the nicotine content to degrade over time. It is also important to check the expiration date on your e-liquid before using it. If the expiration date has passed, then it is best to discard the e-liquid and purchase a new bottle.