Ibuprofen (800 mg) Ibuprofen is a non-steroidal anti-inflammatory best medicine that effectively helps in postponing your periods very easily. You should take 800 mg thrice daily beginning from one or two weeks before your expected date of start of periods. You should accompany ibuprofen tablet with vitamin B6 (double dose). Primolut-N (5 mg) It is effective and the most prevalent medicine in India, which is perfectly utilized for postponing or preponing periods.