IBD is often a painful and debilitating condition. Its symptoms vary depending on the severity of inflammation and where it is located. The common signs and symptoms of IBD include but are not limited to: Abdominal pain and cramping Bloating, distension or gas Persistent diarrhoea, sometimes with blood or mucus Rectal bleeding Loss of appetite Unintended weight loss Fever Fatigue Inflammation of the eyes, skin or joints Delayed growth and sexual maturity in children Many IBD patients tend to experience periods of flare-ups, when the disease is active and causes severe symptoms, and periods with little or no symptoms at all, when the disease is in remission after treatment. Speak to a doctor if you experience persistent bowel problems that last longer than 1 – 2 weeks, or notice any unusual symptoms such as rectal bleeding, lethargy or loss of appetite or weight.