it's fucking impossible, but i do my best.1) autoresponder for immediate feedback; says i'm sorry / i'm overloaded / where i am if on the road, other escalation paths2) assistant that scans some % and helps prioritize3) automatic email tools to help manage response / priority4) delegate to other folks on 500 team to help based on context5) pray i don't miss anything important, altho i know it happens all the time.most 500 companies / founders / mentors / investors have my phone # and can escalate to text / call.  some people go thru my asst to schedule calls/mtgs.(family doesn't usually email me, they just call)ultimately, email / inbox is reactive mode, and i prefer to be PRO-active in focusing on things that matter to me, not RE-active to things that matter to everyone else, but it's always a balance / juggling act.sigh.DMC