Intracellular signaling cascades mediated by the Wnt family of secreted signaling proteins play an essential role in regulating a number of cellular functions, such as proliferation, differentiation, adhesion, survival, apoptosis, and so on. Of their myriad signaling functions, Wnt ligands have been extensively researched for their regulatory effects on early cardiogenic events, during which the linear heart tube is transformed into a multi-chambered heart structure. Read more..