Yes, you can start sisterlocks on relaxed hair. Sisterlocks are a unique way to style your hair that uses tiny interlocking pieces of natural hair, rather than large braids or locks. The process for creating Sisterlocks is the same regardless of whether you have relaxed or natural hair. However, some tips can be followed to make sure that the transition from relaxed to Sisterlocked is as smooth and successful as possible. Firstly, it’s important to allow your hair enough time between relaxers so that it can become strong and healthy before starting the locking process. Secondly, avoid using harsh chemicals like bleach while transitioning; instead opt for color rinses with no ammonia or peroxide products in them. Thirdly, use special moisturizing treatments such as deep conditioning masks once a week to keep the strands hydrated and healthy throughout the transition period. Finally take extra care when combing out and untangling your locks during wash days - this will help ensure minimal breakage over time!