Depending on your mat, you can wash it in your front-load washing machine. Check the label — if it’s machine washable, wash it without bleach on a gentle cycle.
If your mat is thick and open-celled, submerge it in the bathtub with cold water and add some dish soap (1 tablespoon to the gallon) for five minutes. Rinse and dry.
For close-celled, thinner yoga mats, mix warm water with only a few drops of soap. Take a soft rag and dip the corner into the solution. Clean in circular motions, wipe the mat down and dry.