Side effects are limited to the treatment site. The type of side effects experienced depends on the size and location of the cancer and the length of treatment. In general, most patients gradually develop skin irritation or a sunburn-like redness in the treatment area. Prescription creams or lotions are available to help the healing process. Side effects do not usually begin until the second or third week of treatment and peak a few days after treatment is completed. Then, over the course of two to four weeks, the side effects gradually dissipate.