Avoid touching or breathing in any guano personally, just as you would normally avoid any wild animal droppings. You’re actually more likely to get histoplasmosis from bird droppings than bat droppings, but nonetheless, steer clear of bat droppings and be safe. If you’re ever inclined to move your BatBnB or clean it up close during the winter after it’s already been occupied, then be sure to wear proper respiratory masks and goggles, and don’t breath in any dust. In general though, if you’ve never been overly concerned about bird poop in your life, then guano shouldn’t bother you.