Large Language Models (LLMs) are artificial intelligence models designed to understand and generate human-like text. They efficiently synthesize extensive knowledge, aiding e-learning instructional designers and SMEs in delivering engaging, clear, and accurate educational experiences and scripts. Combined with a human-in-the-loop approach and up-to-date microlearning strategies, LLMs prove invaluable in reshaping the landscape of learning, training, and upskilling, while saving up to 50% of SMEs time.