Although Spider-Man is one of the most popular superhero comic characters of all time, he is not without his weaknesses. One of his primary weaknesses is his vulnerability to magic. This weakness was first exploited by Doctor Strange, and has since been used against him by other foes with magical abilities. Another weakness of Spider-Man is his reliance on webbing. Although webbing is incredibly strong, it can be cut by sharp objects or dissolved by certain chemicals. This weakness was famously exploited by the Green Goblin, who used pumpkin bombs to dissolve Spider-Man's webbing and then defeat him. Finally, Spider-Man's greatest weakness is his compassion for others. This compassion leads him to take risks to save lives, even when the odds are stacked against him. As a result, Spider-Man often finds himself in situations where he is outnumbered and outclassed by his enemies. Despite these weaknesses, Spider-Man remains one of the most popular and entertaining superhero characters of all time.