Restylane is a hyaluronic acid dermal filler that is most commonly used to combat volume loss in the lips, but can be used to treat any of the following areas: Nasolabial folds (laugh lines) Fine lines around the mouth (marionette lines) Lip border definition (lipstick lines) Thin lips Corners of the mouth Jowl area This innovative dermal filler can reduce the lines on your face to bring back a more youthful glow to your appearance and smooth out aging skin. Restylane uses the same chemical base as the naturally occurring hyaluronic acid in your own body, so it works together with the tissues it is injected into to create a natural look.