Yes, it is safe to eat black drum with worms. The worms found in black drum are called "spaghetti worms." These worms, which are actually the larval form of a parasitic flatworm, are common in many fish species. While they may look unappetizing, cooking the fish thoroughly will kill and neutralize any potential harmful effects of the worms. To ensure safety, it is important to cook the fish until it reaches an internal temperature of 145°F (63°C), as this will destroy any parasites or bacteria present. Additionally, properly cleaning and inspecting the fish before cooking can help remove any visible worms. It is always a good practice to purchase fish from reputable sources, as they are likely to have undergone the necessary inspections and quality control measures to ensure safe consumption.