Semaglutide Injections help with weight loss because it slows down the process of emptying the stomach by binding to receptors that are found in the lining of the stomach. This sends a message to the brain that the stomach is full, which will assist you in eating less food and having less of an appetite. Since you will feel like you are full and be less inclined to eat as often or as much, this will be important in helping with your weight loss.