The whole point of the self-cleaning or manual-cleaning capabilities of these wall-mounted ovens is the convenience of it all. So, yes! You can definitely use it right after cleaning. However, make sure you know that there might be some steam or evaporation when you use it. We definitely would suggest to set it to a quick 300-degree bake on its own and let it run for 15 minutes with nothing in it. This will help get rid of all the fumes.