Make sure loop points are off 2. Make sure time stretch is set to 0 if you are using fl studio 3. Mode should be auto and/or stretch depending on one-shot [sometimes having the one-shot on stretch mode creates a better sound try it!] 4. Go to "Miscellaneous Functions" on the selected one-shot and click "Cut Self" 5. On the envelope/instrument settings make sure you 0 out the following [rel, sus, dec, att, delay] and set "hold" to 100% 6. After these adjustments you can play around with the attack, sustain, and/or release knobs to get a cleaner sound 7. Always make sure the one shot is in key - most if not all one-shots should already be pitched to "C", however if they are not they will be labeled and/or you must use a third-party website to check key like tunebat.com, keyfinder, and/or auto key