In addition to having a blood pressure-lowering effect, forskolin is used as a treatment for heart failure. Research shows that it can activate or boost a chemical messenger called 3′-5′-cyclic adenosine monophosphate (cAMP), which plays a key role in heart function by controlling both heart rate and the strength of the heart's contractions. However, research assessing the benefits of forskolin for heart health in humans is limited. Therefore, be sure to consult with a healthcare professional before consuming it.