The suggested dosage of spermidine supplements is different depending on the manufacturer’s instructions. However, most brands suggest consuming one capsule per day, which should hold 250mg – 500 mg of spermidine. It is necessary to stick to the recommended dose stated on the label and not exceed it.Different brands of spermidine are available on the market, and it is not easy to determine which is the best. However, it is vital that the brand chosen is as clear as possible about what is in the product and how it was made. Search for brands that apply the best ingredients and leave positive feedback on the internet.Spermidine supplements are non-toxic, and people usually do not experience any side effects from them. However, some individuals might experience side effects, including nausea, upset stomach, and diarrhea. It is recommended to always see your doctor before starting to take any new supplement if one has any medical condition or is on any medications.Surprisingly, there is a comparative lack of literature on how spermidine supplements may impact weight loss. Although it has been discovered that spermidine might help in weight loss, this conclusion is still open for further analysis. Proper nutrition and physical activity are also imperative to successfully keep body weight in check.Liposomal spermidine is the form of spermidine supplement that is incorporated in liposomes, which are small spherical structures composed of fat. This helps in enhancing the uptake and transportation of spermidine to the body cells. Liposomal spermidine might be more potent than other spermidine supplements, although this conclusion will need further investigation.The benefits of spermidine supplements include enhanced cellular quality, a boost of the immune system, and its anti-inflammatory properties. Some of the benefits of spermidine include anti-aging properties and improved brain function. That said, further studies are still required to determine the effects of spermidine supplements.