In order to use honey effectively and regularly, leave honey on your face for about 15 to 20 minutes. It allows enough time to moisturize and nourish your skin. Honey also helps to reduce acne, soothe irritation, and promote a natural glow. Rinse your face after 15 to 20 minutes with warm water, and pat it dry. You can use honey as a facial treatment 2 to 3 times a week.