In OSRS, Dharok's is still meta in PVP scenarios. Guthan's set also comes in handy for certain Slayer tasks. Ahrim's, Karil's, Verac's, and Torag's are all pretty forgettable now. You need one full Barrows set for a Master STASH, so there's that.  In RS3, Barrows equipment is pretty dated. The Guthans set can still come in handy. Ahrim's staff and Karil's crossbow are useful too. You can combine them with a corruption sigil to make a blighted rebounder and tainted repriser. You can combine Dharok's greataxe, Verac's flail, or Torag's hammer with a corruption sigil to get a corrupted defender.