Warning signs of abuse or misuse of cannabis include changes in behavior, increased irritability and anxiety, problems with concentration, impaired coordination and motor skills, sleep disturbances, memory loss, and social withdrawal. Physical symptoms such as red eyes and rapid heart rate can also be present. Withdrawal from cannabis use is associated with intense cravings for the drug as well as nausea, insomnia, headaches, sweating, restlessness and depression. Long-term effects may include an increased risk of developing psychosis or other mental health conditions.