You can definitely use frozen shrimp for shrimp scampi. If you don’t live near water, the frozen shrimp may actually be more fresh than the “fresh” shrimp in the deli.  Frozen shrimp is captured and frozen right away, preserving all its wonderful nutrients. Fresh shrimp may have had a long journey to make it to your local grocery store. You can thaw frozen shrimp under cold water or simply add it to your pot and cook from frozen. Be sure and read the directions for the recipe you are using to see what is recommended. You may or may not need to adjust your overall cooking time. ​I also recommend using deveined shrimp to save time.