Fentanyl withdrawal treatment may initially include switching the patient to a different opioid, for example methadone or morphine. After this switch has been made, opioid levels are reduced by about 20-50 percent every day. When the dosage reaches 45 mg/day for morphine, it can be reduced by 15mg every 2-5 days, and by 5mg every 3-5 days down to 10 mg/day. If methadone is used, the dosage can be reduced by 15mg every 3-4 days when it reaches 30 mg, and by 2.5mg every 3-5 days, until it reaches 0.