A basic rule of biology is that men and women have different needs within their bodies. The biggest difference between male and female supplements lies in the need for iron. Men do not typically require as much iron as women, because they do not menstruate. Females often lose a lot of iron while menstruating, so this additional iron in their supplements will work best for them. Too much iron for males can lead to heart disease. Females also need more calcium than their male counterparts because as they age they are more susceptible to osteoporosis, which is a thinning of the bones. Females typically have supplements that will help with hair and nail growth, as well as promote healthy skin- something that many men are not too concerned with. Female supplements also contain ingredients that will help with reproductive and breast health, while men’s offer supplements that aid in prostate health. The bottom line here is that it is important that you select a gender specific brand that will cater to your specific needs.