Businesses developing and employing nanotechnology follow applicable U.S. laws and regulations, including the Toxic Substances Control Act (TSCA), the Clean Air Act and the Clean Water Act, as well as numerous existing laws around the world concerned with the production and use of chemical substances. Innovators and leaders in nanotechnology work to ensure the responsible development of nanotechnology. All participants involved in the life cycle of a product—including production, distribution, use and safe disposal—have a part in understanding and communicating possible impacts to human health and the environment.