Nootropics work by changing the levels of certain chemicals in the brain and the way those chemicals interact with each other.Different nootropic compounds each have their own unique mechanism of action (MoA), a biochemical interaction through which a compound produces its effects. Some of these biochemical interactions include supporting mitochondrial function and energy production, reducing oxidative stress, mediating the body's homeostasis, stimulating the central nervous system, and supporting the formation of synaptic connections in the brain.One of the primary biochemical interactions nootropic compounds work through is modulating brain chemicals, otherwise known as neurotransmitters, which are responsible for our mood, focus, appetite, memory, pain, and anything else you can think of. By changing levels of certain neurotransmitters, we can change certain traits. And by changing these levels, it will lead to changes in the way we feel.