Finding the best match for a kidney transplant is important because the better the match, the more likely it is that the kidney will last longer. The National Kidney Registry uses the latest generation in DNA sequencing technology to assess the match between patients and donors. Traditionally, kidney transplant matches were measured by an HLA match score of zero to six. This score was based on antigens. Behind antigens are eplets, which are essential components of HLA epitopes recognized by antibodies. Eplet mismatch analysis has been proven to be a more precise measure of a donor-recipient match compared to antigen matching, and can potentially lower the probability of rejection and graft failure, as well as enable the recipient to safely reduce the immune-suppression medications they must take after the transplant is complete.