In general, yes. However, when using several serums at the same time, we do recommend that you restrict the application of one serum to a particular area (e.g. Blue Serum on the cheeks, Green Serum in the eye area). You should not apply the serums on top of each other, as the penetration of active ingredients cannot be guaranteed in that instance. The best solution is to allocate one time of the day to a specific serum. If, i.e., you would like to help protect your skin from photoaging and counteract existing fine lines, you can use the Yellow Serum in the morning and the Pure Hyaluronic Intense Serum or Nude Serum at night.