Yes, sensitive individuals may develop skin reactions while using Fuzole-Plus Tablet. There are rare reports of people developing serious skin/hypersensitivity reactions like Stevens-Johnson syndrome, toxic epidermal necrolysis, and other severe skin reactions with Fuzole-Plus Tablet. Therefore, do not take this medication without consulting your physician. And, in case you encounter any type of skin reaction or rashes, stop the medication immediately and report to the doctor.