Multiple studies have found that artificial sweeteners can have several negative side effects. Some people may experience stomach issues, such as bloating, gas, and diarrhea. There's also evidence to suggest that artificial sweeteners can increase cravings for sweet foods, which can then lead to weight gain. Also, some research has linked artificial sweeteners to an increased risk of metabolic disorders like type 2 diabetes. So, it's always best to consult a healthcare professional if you have concerns about artificial sweeteners in your diet.