There are a few references to plagues in the last days throughout the Bible. One example can be found in Revelation 16:1-21, where it talks about the seven bowls of God's wrath that will be unleashed on the earth. Another example is found in Ezekiel 38:22, where it speaks of a time when God will rain down fire and brimstone on Gog and Magog. Jesus also spoke about plagues as one of the signs that would precede His return to earth. (See Matthew 24:7-8.)