Carpal Tunnel syndrome is a condition caused by pressure on the median nerve in the wrist. It can affect one or both your hands. The symptoms start gradually and may include: Tingling or numbness, especially in the fingers and hands. The thumb, index and middle fingers are usually affected, where you might feel an electric shock-like sensation. These sensations are more pronounced when you wake up from sleep or hold a steering wheel, phone or newspaper. Weakness in your hands or grip that causes you to drop objects. Weakness and numbness in hands could be signs of other ailments, so get checked by a specialist at the earliest.