As with any surgical procedure, a partial knee replacement comes with some risks. Risks of partial knee replacement surgery General risks of knee replacement surgery include: Blood clots, which are common in the legs or pelvis and could cause a heart attack or stroke if they travel to your heart or brain Buildup of fluid in the knee joint Infection, which can happen at the surface of your skin or deeper within the surgical site Damage to nearby nerves or blood vessels, although this is uncommon Reaction to the anesthetic Partial knee replacement complications Most partial knee replacements are successful, but potential complications include: Failure of the prosthesis—the replaced joint parts do not remain attached to the knee Dislocation or loosening, which may require additional surgery to secure the new joint Continued pain and stiffness Wear and tear of the new joint, especially if you continue doing high-impact activities such as running. This wear can eventually lead to a total knee replacement surgery. Reducing your risk of complications from surgery You can reduce your risk of some surgical complications by: Resuming light activity and possibly physical therapy right away Using a walking aid, such as a cane or crutches, if necessary Taking blood thinners (temporarily) to prevent blood clots from forming Taking a prescription antibiotic to prevent infection Taking pain relievers if your doctor recommends them Notifying your doctor immediately of any concerns, such as bleeding, fever, or increase in pain Telling your surgical team if you have allergies