Using BTC payments system in Bitcoin casino is generally safe for players. The Safety of the system is based on its blockchain technology that employs the Proof-of-work system, and every transaction made must be confirmed as valid by a consensus mechanism.
The consensus mechanism is made up of independent decentralized miners. Once the miners agree that the transaction is valid, the bit coin casino will receive a deposit or process a withdrawal request from a client. This means an invalid or fake transaction will not work with this payment system.