The choice between Botox and hyaluronic acid depends on the indications. Botox is indicated for smoothing expression lines caused by muscle movements, such as forehead wrinkles and crow's feet. Hyaluronic acid, on the other hand, is a filler used to add volume, fill in deep wrinkles and hydrate the skin. The two treatments can be complementary and are often used together for a complete rejuvenation of the face.