People who are pregnant or breastfeeding should avoid using acai berry supplements, as there is not enough research available on the safety of these supplements in these groups. Additionally, people with certain health conditions such as gastrointestinal disorders or heart disease should consult their healthcare provider before consuming acai berries, as they may interact with other medications or exacerbate existing health conditions. Overall, it is best to speak with a healthcare provider before starting any new supplement, including acai berries.