Cyclosporin is an oral medication classified as an immunosuppressant. It impedes the body’s normal defense mechanisms from rejecting transplants and reacting against inflammation. Kidney, liver, and heart transplant patients all take this medication so that the replacement organ is not rejected. Cyclosporin has also been used in a wide variety of skin and joint diseases. It has been given to severe red skin syndrome patients with great success. Its mechanism of action is unknown.