CoolSculpting uses an applicator that freezes unwanted fat cells. Kybella is injected directly into the fat pad under your chin and jawline. The active ingredient in Kybella, deoxycholic acid, is naturally occurring in our bodies and aids in the breakdown and absorption of the fat we consume in our foods. Both CoolSculpting and Kybella are effective treatment options with similar outcomes. What sets Kybella slightly apart is that Kybella gives your injection specialist more freedom to customize your treatment by injecting Kybella right where you need it most.