To achieve the best quarter-mile time in a drag race, drivers must have a well-tuned car and use proper driving techniques. The car must have the right combination of horsepower, torque, weight, and aerodynamics. The driver must use proper throttle and steering control to maintain traction and avoid wheel spin. Launch technique is critical, and drivers must choose the right RPM and launch speed for their car and track conditions. Shifting must be timed correctly to maximize acceleration. Consistency is key, and drivers must practice and refine their technique to achieve the best possible time.