Yes, fluoride treatments can be particularly effective in reducing tooth sensitivity. Fluoride strengthens the enamel, which can wear down due to various factors, exposing the dentin and leading to sensitivity. By enhancing the enamel's strength, fluoride helps to block the pathways to the nerves in your teeth that cause sensitivity. Over time, regular fluoride treatments may significantly reduce the discomfort associated with sensitivity to hot, cold, or sweet stimuli.