To uninstall KMSpico, you can follow these steps: first, open the Control Panel on your Windows system. Navigate to ‘Programs and Features’ and look for KMSpico in the list of installed programs. Click on it and select ‘Uninstall.’ After the uninstallation, it is recommended to run a thorough antivirus scan to ensure that any remaining files or components of KMSpico are removed from your system. Additionally, check your Windows activation status to confirm that everything is functioning properly after the removal.