The US Powerball is one of the lotteries with the biggest jackpot prizes. It holds 12 of the top jackpots with the highest amounts in the history of jackpot winnings in the US. Its large amounts have been known to climb to great amounts with some rising to more than $750 million even before its final tickets have been added up. The US Mega Millions follow closely with gigantic jackpots amounts with a winner once bagging the $451 Million prize in 2018.