Stephane de La Rocque, WHO: The Tripartite Zoonoses Guide highlights over 80 country examples, ranging from the development of effective government One Health mechanisms or platforms, to zoonotic disease prioritization, joint risk assessment, planning and preparedness, investigation and response, coordinated surveillance and workforce development. Designed for decision makers and technical staff in countries, we recognized the need to create operational tools to support implementation of key principles. Three operational tools have been developed so far to support a step-by-step One Health approach in countries for joint risk assessment, multisectoral government mechanisms, and coordinated surveillance and information sharing. These tools are facilitative and adaptive to country context and allow for sustainable and iterative use as needed.