The main difference between skin boosters and dermal fillers lift and longevity. Skin boosters add hydration, glow and restore elastin while dermal fillers add volume and soften lines to restore a more youthful appearance.   Both treatments use key ingredient of hyaluronic acid and are injected under the skin using a needle. Dermal fillers can last anywhere from 9 to 12 months while Skin boosters will last up to 6 months and will need more regular maintenance.