Ultimately you will want to play to each slayer's strengths and capitalize on their unique Innate Abilities. Moreover, each of the three types of slayer classes is designed to either dodge or block, with Jacob and Dani being an exception. For Amy and Jacob, you will want to equip the Dodge Skill, as dodging is where these characters get most of their speed and damage from. However, I will admit that dodging is underwhelming from my time playing Dead Island 2 compared to blocking. This is because the blocking mechanic allows you to spam the block counter button, effectively making it impossible for zombies to hit you. You can't do this with dodging since it's a directional step. If you were to spam the dodge button in a swarm of zombies, you would end up dodging another zombie attack. However, circling 1-3 zombies is a sound strategy.