Yes, Southampton is one of the most popular cruise ports in the UK with many cruises departing from it. Major cruise lines operating from Southampton include P&O Cruises, Royal Caribbean and Cunard. The port of Southampton is easily accessible by road, rail and air, making it a convenient starting point for cruise passengers. Many cruises from Southampton sail to destinations in Europe, such as the Mediterranean, the Canary Islands and the Norwegian Fjords, as well as to destinations further afield, such as North America and the Caribbean.