Vo filme Drakula: Zrod legendy hrajú Luke Evans (Dracula / Vlad Tepes), Dominic Cooper (Mehmed II), Sarah Gadon (Mirena / Mina Murray), Charles Dance (Master Vampire), Art Parkinson (Ingeras), Diarmaid Murtagh (Dimitru), Ronan Vibert (Simion), William Houston (Cazan), Ferdinand Kingsley (Hamza Bey), Zach McGowan (Shkelgim), Paul Kaye (Brother Lucian), Thor Kristjansson (Bright Eyes), Arkie Reece (General Ismail), Noah Huntley (Captain Petru), Joseph Long (General Omer), Jakub Gierszał (Acemi), Joe Benjamin (Mihai), Paul Bullion (Nicolae), Mish Boyko (Andrei), Dilan Gwyn (Governess), Phil Zimmerman (Mihai's Father), Dominic Borrelli (Wealthy Boyar), Tom Benedict Knight (Turkish General), Paul Casar (Intrigued Boyar), Stavros Demetraki (Mehmed's Adjutant), J.J. Murphy (The Village Elder), Ruth Baxter (Mirena's Handmaiden), Rachel Kennedy (Mirena's Handmaiden), Louise Parker (Mirena's Handmaiden), Glen Barry (Lucian's Monk), Shane McCaffrey (Lucian's Monk), Gary Whelan (Lucian's Monk), Guillaume Meliot (Omer's Adjutant), Jason Coalter (Vlad's Castle Guard), John Friel (Vlad's Castle Guard), Andrew Laverty (Vlad's Castle Guard), Cole Currin (Vlad's Castle Guard), Matthew Åkerfeldt (Vlad's Soldier), Eugene Furphy (Vlad's Soldier), Chris Cherry (Vlad's Soldier), Graham Hutton (Vlad's Soldier), Chris Keenan (Vlad's Soldier), Ross Moneypenny (Vlad's Soldier), Joe Kelly Jr. (Vlad's Soldier), Bobby Marno (Vlad's Soldier), Phil McKee (Vlad's Soldier), Darren McMullan (Vlad's Soldier), Andrew McQuade (Vlad's Soldier), Connor Schelling-Tisza (Vlad's Soldier), Paul Monahan (Boyar Man), Norman Coates (Boyar Man), Tyrone Kearns (Boyar Man), Gordon Bell (Boyar Man), Paul Kavanagh (Boyar Man), Graham Cave (Boyar Man), Arthur Halligey (Boyar Man), Derek Mayne (Boyar Man), Al Geddes (Boyar Man), Gavin McCormick (Boyar Man), Xander Duffy (Boyar Man), Jeffrey O'Brien (Boyar Man), Gretta Shore (Lady of the Court), Charlene Gleeson (Lady of the Court), Orlaith Shore (Lady of the Court), Penelope Simmons (Lady of the Court), Ann Louise Bresnaham (Lady of the Court), Ann O'Connor (Lady of the Court), Aodhan McGowan (Child of the Court), Hunter Stratton Boland (Child of the Court), Maria Laird (Child of the Court), Frank Cannon (Monk No6 (uncredited)), John Carr (Market Shopper (uncredited)), Micheal Fay (Bright Eyes' Janissary (uncredited)), Richard Hansen (Adjutant (uncredited)), Sarah-Louise Haveron (Dead Peasant (uncredited)), Joana Metrass (Handmaiden (uncredited)), Felicity McKee (Peasant (uncredited)), Niall Murphy (Terrorised Turk (uncredited)).