It is unclear whether taking proton pump inhibitors (PPIs) such as omeprazole may increase the risk of developing dementia or Alzheimer’s disease. There is some limited evidence that there may be a link between PPIs and these diseases, but some other studies have suggested that PPIs may even be linked to a reduced risk of developing these diseases. In summary, there is no clear link between omeprazole and dementia or Alzheimer’s disease, and you should continue to take omeprazole as directed by your doctor.