No, you cannot. Dye colors mix perfectly and transparently. If you dye a blue shirt yellow it will be green. Removing color on natural fabrics is fairly easy with our Color Remover or even bleach (can damage fabric). Color on nylon can be removed, but removing color from polyester is extremely difficult. For natural fabric, pink to red transitions are easy as are blues to green. Black to red or purple to yellow type of transitions must begin by removing the original color. Dyeing darker is always easier than lighter.