There are a large number of diseases and conditions that can cause a thickened gallbladder wall. Some of these include acute cholecystitis, renal failure, cirrhosis, pancreatitis, primary gallbladder carcinoma, acute acalculous cholecystitis (AAC), congestive heart failure, and hepatitis. Both ultrasound and a CT scan can be used to detect gallbladder wall thickening.