It’s unlikely that Eliquis will cause erectile dysfunction (ED).However, if you’re taking Eliquis, it’s likely that you have risk factors for ED. Risk factors for ED are similar to those for blood clots, which Eliquis is used to manage.Examples of risk factors include:heart diseasehigh blood pressurediabetesolder ageoverweightIf you’d like to know more about causes of ED, talk with your doctor or pharmacist.