Water edema syndrome Pacman frog (also known as WES) is a rare medical condition that affects certain species of frogs, specifically the horned or pacman frogs. It causes an accumulation of fluid in body cavities, resulting in bloating and swelling that can be life-threatening if left untreated. The primary symptoms are respiratory distress, lethargy, poor appetite and swollen limbs. In some cases, other organs may also become affected such as the liver and kidneys. Treatment typically involves antibiotics to address any infections present as well as careful monitoring of water levels and electrolyte balance in order to prevent further complications from arising. With prompt treatment, prognosis for survival is good but it is important to keep an eye on your pet so that any changes can be identified early on for optimal recovery.