Handling technical difficulties gracefully is crucial. It's recommended to have a rehearsal to anticipate potential issues, ensure a stable internet connection, and prepare backup equipment. During disruptions, communicate transparently with your audience about the issue and expected resolution time. Engaging the audience with pre-prepared content or interactive Q&A sessions can help maintain interest during longer down times. Also, make sure to have a back up speaker that can take over if the issue is isolated on the speakers end.