Canadian Parks and Wilderness Society – protect our parklands, wetlands and the wilderness that depends on it.  This is a good choice for the environmentalist and animal enthusiast. Our Canadian wildlife and environment are known around the world, let's help keep them pristine and protected. The Ontario and Vancouver SPCA are some of North America's largest shelters. If you are looking for the number of animals you can help these are both great options.  They do great work, and have a large number of animals in/out of their shelters every year.  If you are looking for a shelter, there is sure to be one close to you or even pick a remote Northern location where the needs could be great but they are stretched for resources because the cost of animal rescue may be significantly higher just because of the territory they need to cover. African Wildlife Foundation – is a charity based in the Kenya, but with offices in the US.  They focus their work on natural preservation but have a specific focus on animals that are at threat of going extinct. World Wildlife Fund (WWF) The World Wildlife Fund is perhaps one of the best-known organizations for the protection of endangered species and their habitats around the world. They work around the world, and work hard to raise awareness of the plight of animals and the threat of the human species to their ongoing welfare. Best Friends Animal Society was founded decades ago, Best Friends Animal Society is the United States' largest no-kill shelter for companion animals such as cats, dogs, and horses. A good choice if pets are your passion.  No-kill shelters typically require more resources to run, and your donation will help ensure they can continue to run even when the shelter is full. The Humane Society is probably one of the most well-known animal welfare organizations.  They have a number of programs in many countries to support pets, but they have launched broader initiatives against inhumane practices for wildlife hunting, factory farming and animal testing.  They are focused on the broader change that can happen and are a strong advocate voice for animals around the world. Animal Charity Evaluators The Humane League Good Food Institute Albert Schweitzer Foundation Animal International