The amount of weight you may actually reduce in a short period of time is determined by several factors, including your beginning weight, age, gender, and overall health. A weekly weight reduction of 1-2 pounds is regarded as safe and practical. However, due to water weight loss, it is possible to lose more weight in the first few weeks of a weight loss program. Losing more than 2 pounds each week is not advised since it is tough to maintain and may result in muscle loss.