Yes, KMS Pico is designed to activate various versions of Windows and Office, including Windows 7, 8, 10, and different editions of Microsoft Office. It works by leveraging the KMS activation process, which allows it to activate multiple installations on the same network. However, the success of activation may depend on the specific version of the software and the system configuration. Users should ensure they are using the correct version of KMS Pico that matches their software for optimal results.