This is a frequently asked question in MYSQL interview questions for freshers.   PDO is PHP Data Objects.  PDO will work on 12 different database systems, whereas MySQLi will only work with MySQL databases. So, if you have to switch your project to use another database, PDO makes the process easy. You only have to change the connection string and a few queries. With MySQLi, you will need to rewrite the entire code - queries included.