First, you should remove your bearded dragon from its enclosure. Next, use a reptile-safe cleaner, a 50/50 vinegar and water solution, or a ten-to-one ratio of water to bleach solution. Be sure to rinse everything thoroughly before returning your bearded dragon to its tank. This deep clean should be done once a month, but a reptile's substrate should be spot cleaned daily, and the dishes should be washed at least a few times a week.