The traditional delivery methods for hormone replacement have been pills, skin patches, gels, spray foams, or through vaginal tablets, creams, or rings. Pills lose potency through the digestive system, and they bring liver reactions into play. All of the other options involve manual application of some sort. This can be inconsistent if a person forgets an application. The closest thing to the ease of pellet delivery is the transdermal patch. But many women don’t like the patch being there during intimacy.