Unfortunately, there are no creams, pills or other non-surgical products that have been shown to enlarge the breasts. In fact, some can have serious effects on the body. For instance, some pills and supplements can interact with certain medications and lead to serious health complications. The only safe and effective way to add volume and shape to the breasts is with the placement of saline or silicone implants. Both types of breast implants are extremely safe and some of the most studied medical devices in the world.