Yes. Fortunately, many popular eCommerce platforms—including WooCommerce, Shopify, and BigCommerce—allow for high-risk merchant account integration. While you may not be able to take advantage of in-house payment services (such as Shopify Payments) you should be able to integrate a third-party payment gateway with the platform. However, some products are entirely banned from Shopify, WooCommerce, and other eCommerce platforms, so make sure you abide by each provider's terms and conditions.