Don't jiggle the bottle. Sediment will only hurt your pen, thus you don't want any sediment sucked into it. If the sediment is excessive, I discard the ink container. It simply isn't worth the risk. The short answer is that you should not shake a new ink cartridge. The process of shaking out the air bubbles creates more opportunities for leakage to occur as well as reducing the effectiveness of the ink as a liquid. However, there are two situations where a little shake-up can be useful: 1 if you need to use up some old ink before buying a new one and 2 if you have clogged up your pen with too much pigment. In both cases, lightly shaking the cartridge will help release any trapped gases inside and also break up any large particle contaminants that may have made their way into the ink during manufacturing. This will allow you to get the most out of your new ink purchase! However, don't overdo it! Shaking the cartridge too vigorously could cause damage to the ink itself or to your pen tip. If you do happen to leak some ink while shaking, immediately stop what you're doing and try not to touch the area around your writing instrument until someone can come and give you a hand.