The setting lotion will last, on average, 2 to 3 days. This can vary based on your hair type and the precautions you take to maintain your style.  Thin, straight hair might begin flattening after 1 to 2 days, while naturally curly hair might retain the same style for a week without issue. Using silk pillowcases, wearing silk wraps or nightcaps, or resetting your rollers at night may help your style keep longer.