FDA-approved cosmetic indications Jeuveau and Botox are both FDA-approved for treating moderate to severe glabellar lines (frown lines). Off-label uses Jeuveau, like Botox, is used off-label for treating forehead lines, crow’s feet, and lower face and neck lines. Cost The cost of Jeuveau is comparable to Botox, ranging from $10-$20 per unit. Onset of action & Longevity Jeuveau has a similar onset to Botox (3-5 days) and lasts approximately 3-4 months. Units used The dosing for Jeuveau in cosmetic treatments is typically the same as that of Botox