Yes, of course!And of course, microwave popcorn is already salty, so our seasonings will taste a little saltier than usual.But since most of our seasonings are low in sodium, it should be just as good!(We recommend Pink Salt seasoning only on plain microwave popcorn)Just make sure the popcorn is a little greasy so the seasoning sticks to it.If it is too dry, follow the instructions for plain popcorn: Season your popcorn like a PRO