Eating spicy food can make your mouth feel like it's on fire, especially if you're sensitive to hot spices. Once your digestive system gets to work, your stomach might feel a similar level of discomfort. That's because capsaicin, the substance that makes spicy food taste so hot, can make your digestive system feel the same burn. Although everyone reacts differently to spicy food, most people experience a few common symptoms. These over-the-counter solutions can alleviate the discomfort that spicy food often causes: Antacids and heartburn relief medications can address pain related to acid indigestion. For immediate relief, look for a chewable form that's designed to act quickly. Capsaicin often speeds up the digestive process, which may cause diarrhea. Antidiarrheal tablets can give your digestive system a break and prevent extra trips to the bathroom.