Taking cocaine once—like any substance—may not immediately result in addiction. However, since it is so hard to ever tell for sure what is in the cocaine that you are taking, it is possible that you may overdose on cocaine or any other drugs laced in the cocaine. You may also experience symptoms like a racing heart, headache, nausea, sweating or more. Cocaine is highly addictive as well, so you may notice a craving for cocaine after a few uses.