The optimization and scaling up of the catalytic enantioselective synthesis of nortricyclanes for industrial applications can be achieved through several strategies. Firstly, the development of more efficient chiral catalysts that can enhance the enantioselectivity of the reaction is crucial. This can involve exploring different ligands, tuning reaction conditions, and conducting extensive screening to identify the most effective catalysts. Additionally, process optimization to increase the reaction yield and reduce by-products is essential for industrial scalability. This may involve fine-tuning reaction parameters such as temperature, pressure, and solvent choice. Furthermore, the development of continuous flow processes can streamline the synthesis and improve productivity. Continuous flow systems offer better control over reaction conditions, higher throughput, and easier scale-up compared to batch processes. Lastly, collaboration with chemical engineering experts to design efficient reactor systems and purification methods can further optimize the synthesis of nortricyclanes for large-scale production.