There is no definite answer to this question as there are no scientific studies that have been conducted on the safety of contact lenses while the mascara is being used. However, based on the evidence that exists, it seems reasonable to assume that contact lenses and mascara can be safely worn together. In general, it is generally accepted that eye products should be appropriately tested before they are marketed to consumers, but there is no guarantee that any particular product will be free of adverse effects when used in combination with other products. It is always best to speak with a doctor before making any changes to your eye care routine.