Press the [Fn] key, and keep it pressed. Press the [Esc] key, and keep both [Fn] and [Esc] pressed. Press and release the [key being programmed] one time until it starts blinking. You need to be pressing the 3 keys at the same time until the [key being reprogrammed] starts blinking. Then release these 3 keys. Then press the key corresponding to the desired functionality you want to use, according to the list below, like [F1] for Tab. The [key being reprogrammed] stops blinking. If continue blinking, press the key as mentioned above. You can reprogram the programmable keys as many times as required. You can press [Fn][Esc][R] to reset the keyboard to the factory defaults; this deletes all Macros and resets all layouts and keys. [1] = Space [2] = Backspace [3] = Delete [4] = Enter [5] = Shift [6] = Ctrl [7] = Alt (Left Alt) [8] = Windows/command [9] = Menu/Apps [0] = Esc [F1] = Tab [F2] = Shift+Tab [F3] = – [F4] = Fn [F5] = F16 [F6] = F17 [F7] = F18 [F8] = F19 [F9] = F20 [F10] = AltGr (Right Alt) Example: Press and release [Fn][Esc][Central-Shift] (Central-Shift blinking) Press the [2] key (Central-Shift key becomes a Backspace) (Central-Shift stops blinking)