Semaglutide works in the body in multiple ways. First, by helping increase insulin levels in the body, which decreases blood sugar levels, these medications help to control blood sugars. Next, Semaglutide affects the hormone GLP-1. This hormone controls how the food in your stomach is emptied, slowing the process and keeping you feeling full longer. It also acts on the pancreas and its ability to release insulin. In addition, it also reduces the ability of the liver to release sugar into the bloodstream and slows down digestion and how fast your stomach empties. All of these combine to suppress appetite and how your body processes food, resulting in weight loss.  When starting skinny shots, you start on a small dose and gradually increase to the target dosage. The levels will be increased about every 4 weeks until the maximum dose is reached, often around the 20-week point. People lost weight during the initial phase and continued to lose weight after they were on the target dosage of Semaglutide. Most patients continued to lose weight during their time on the full dosage as well.