Syphilis is easiest to cure in its early stages. It can be treated with a single injection of penicillin or, if you are allergic, another antibiotic. A single injection can typically stop the disease from progressing, but if you have had syphilis for longer than a year, additional doses may be required. After you have been treated for syphilis, it is important that you follow up with your provider. Your provider may recommend that you:
Have periodic blood tests and exams to make sure you are responding to the penicillin.
Avoid sexual contact until your treatment is complete.
Notify your sexual partner(s) so he or she can also be testing and seek treatment if necessary.
Be tested for HIV, and possibly follow with further VDRL titers