Pure aloe vera can be expected to cause an allergic reaction in some people. Ayr Saline Nasal Gel contains only a small part of aloe. In the life of the product, there have been no confirmed instances of allergic reaction to Ayr Gel attributed to the aloe. Potential users that should be aware of the possibility of allergic reaction are those with a known allergy to plants of the family Liliaceae – lily, daffodils, narcissus, iris, tulip, onion, and garlic – as aloe is a lily relative.