Fat deposits on the body can be stubborn, refusing to budge no matter how much you diet and exercise. CoolSculpting is a localized treatment designed to target those unwanted bulges specifically. Fat cells generally cannot survive temperatures below 4 degrees Celsius. CoolSculpting works by reducing tissue temperature as low as -11 degrees Celsius, crystallizing a percentage of the fat cells in the subcutaneous layer. Those crystallized cells are permanently destroyed.