Skunk is a hybrid that combines indica and sativa traits, and its gene ratio is estimated at approximately 75% sativa and 25% indica. In general, Skunk strains tend to have a more relaxing effect on the body, however, they also produce a cerebral and euphoric high, suggesting a strong sativa influence. It is important to note that there are several Skunk strains, and each can vary in their sativa to indica ratio, as well as in their flavor profiles and effects.