Absolutely, in-fact they are great at absorbing sweat down there too! They don't cause any chaffing or uncomfortable rubbing, due to the ultra soft, silky feeling material. If running or walking then it may be slightly bulky to use the MAXI Pads, but you will be absolutely fine with a MINI or MIDI. If you are riding a bike, then the MIDI and MAXI sizes are perfect, due to the fact they are cushioning, we could almost call them 'shock absorbent' too! The poppers do not sit directly underneath your moo, but instead slightly behind, so you won't feel them when sitting on the bike.