The treatment of uncomplicated cystitis does not always require antibiotic treatment and in most instances will resolve without their use. Unnecessary use of antibiotics not only burdens the body but can become ineffective if taken too often. The global rise in antibiotic resistance has led to an increase in the development of national and international clinical guidelines addressing the management of UTIs, with specific attention being given to the adoption of non-antibiotic therapies to help contain antibacterial resistance.