No, the RAM 3500 is not comfortable. It's a work truck, not a luxury vehicle. That being said, it's not uncomfortable either. The seats are firm and offer plenty of support, so you won't be getting sore on long trips. And even though it's a big truck, visibility is good all around thanks to the large windows. So while it's not going to be winning any comfort awards, it won't leave you feeling beat up at the end of the day either.