BioClean refers to the exceptionally high standard to which all Rainin air-displacement tips are tested and found to be free of detectable amounts of specific biological contaminants, such as DNA (human and bacterial), RNase, DNase, endotoxin, protein, protease, ATP and PCR inhibitors. BioClean Ultra pipette tips are manufactured in a fully automated class 100,000 clean room facility. To assure absolute purity, no additives or dyes are used, and ISO 9001-compliant manufacturing procedures are followed to eliminate all external sources of contamination. From raw material selection to clean production and automated packaging, Rainin BioClean Ultra pipette tips are pure and completely safe.