Start this medication 1-2 days before you enter the high-risk malaria area, continue for the entire duration of your stay and for 28 days after you leave the affected area.
Take 100 mg daily (one tablet) daily, on an empty stomach with a full glass of water, and remain in a sitting/ standing position for 60 minutes after.
Avoid calcium, magnesium, aluminium, zinc and iron for 1-2 hours before and after taking this medication as they can affect absorption (this includes vitamin supplements and dairy products).
If you miss a dose, take it as soon as you remember. If it is almost time to take the next dose, then skip the missed dose - you should not take 2 doses together.
Ensure you complete the course.