Some BBQ sauces contain ingredients that are derived from gluten-containing grains, such as wheat, barley, or rye, and are therefore not gluten-free. Other BBQ sauces may be made with gluten-free ingredients, such as gluten-free soy sauce or vinegar, and can be suitable for those following a gluten-free diet. To determine if a BBQ sauce is gluten-free, it's important to check the ingredient list and look for any mentions of wheat, barley, rye, or other gluten-containing ingredients.