In general, the stock 6R80 can handle the torque without issues as long as you're not hitting the drag strip every weekend and doing hard launches and making sure it's up-to-date on fluid and filter changes. As long as your motor is in good running condition, you can still use this supercharger at 100,000 miles, but you should probably give it a good once-over and get it compression tested and/or leak-down tested before taking the plunge on this supercharger system.