THC has potential therapeutic effects on the liver. Studies have shown that THC can reduce inflammation, improve liver function, and protect against liver damage caused by toxins or infections. In animal models of non-alcoholic fatty liver disease (NAFLD), THC reduced levels of markers associated with inflammation, fibrosis, and oxidative stress in the liver. Studies have also found that THC may help to regulate glucose metabolism and prevent insulin resistance in patients with NAFLD. In a study using mice infected with hepatitis C virus (HCV), THC was able to reduce HCV-related inflammation and hepatic injury by inhibiting inflammatory pathways. Research suggests that THC could be used as an effective treatment for chronic cholestasis–a condition characterized by blocked bile flow from the gallbladder–as it has been observed to increase bile flow in animal models of this condition.