Yes, Cabenuva (cabotegravir and rilpivirine) is a long-acting injection used to treat (but not prevent) HIV-1 infection. Cabotegravir is an antiviral integrase strand transfer inhibitor (INSTI) and rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). These medicines keep HIV from multiplying in your body. The brand name Apretude only contains cabotegravir and is used as a long-acting injection for HIV prevention (PrEP).