One event = acute moment. No cycle is formed. Pain in migraine 2-3 days – creates inflammation in the dura – usually lasts 2-3 days – that’s the time the body needs to recover from an inflammatory event. The fear of having the next attack – lowers the threshold to create the next attack. Through repetition – our biology – is taught to respond to repetition – if you have an attack every day at the end of the day your brain doesn’t need much more to remind it to have an attack. It's forming a negative cycle into having more and more pain, the sooner you stop the vicious cycle the better. The system is trying to correct the pain cycle – something to correct the problem – but they don’t understand it yet.