Alkylating agents: They damage the DNA strand and prevent mitosis in cells. They are used for the treatment of various types of cancers such as leukemia, lymphomas, sarcoma, etc.
Anti-metabolites: They interfere with the cell replication and proliferation process. There are various subclasses within this class such as folate antagonists, purine antagonists, and pyrimidine antagonists.
Anti-tumor antibiotics: They inhibit enzymes responsible for DNA replication.
Topoisomerase inhibitors: They inhibit the enzyme topoisomerase 1 or 2 responsible for facilitating DNA replication, thereby inhibiting replication in the host.
Plant Alkaloids: They are derived from plants, they act by inhibiting mitosis cell division, and are also known as mitotic inhibitors.
Corticosteroids: This class includes hormones and their analogs as a part of treatment.