Get emergency medical help if you have : hives; difficult breathing; swelling of your face, lips, tongue, or throat. signs of an allergic reaction Stop using miconazole topical and call your doctor at once if you have: severe blistering, redness, or irritation of treated skin. itching, peeling, or dry skin. dry mouth, sore tongue, tooth pain, red or swollen gums; altered sense of taste; nausea, diarrhea; or headache. Common side effects may include: Although the risk of serious side effects is low when miconazole topical is applied to the skin, side effects can occur if the medicine is absorbed into your bloodstream, including: This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.