Soursop contains several plant compounds that have biological activity and may contribute to its health benefits. One of the most studied compounds is annonacin, which belongs to a group of chemicals called acetogenins. Annonacin has been shown to have anti-cancer, anti-inflammatory, anti-diabetic, and neuroprotective properties in test-tube and animal studies. However, more research is needed to determine the safety and efficacy of annonacin in humans. Annonacin may also have toxic effects on the nervous system and liver at high doses or prolonged exposure.