High on Knife is a new DLC expansion for High on Life, which adds a new story, environment, characters, and features to the game. The DLC focuses on Knifey, the sentient knife who loves to stab things, and his quest to fulfill his destiny. The DLC also introduces two new guns, Harper and BALL, and a new villain, Mux. The DLC has a horror-comedy vibe, with more blood, gore, and scares than the base game.