No. A PC or laptop is only used while flashing a tune or logging live data. Once you have a tune that you are satisfied with, it is saved to the car and replaces the factory program. It stays on the car even after you disconnect your battery and until you replace it with another tune or return the vehicle to stock.
In data logging mode keyboard shortcuts and audible alerts are provided to keep distractions to a minimum. A compact netbook or tablet PC makes data logging even more comfortable.