Yes, the Echo show works with the Nest thermostat. Alexa can adjust your thermostat or set a schedule for your Nest thermostat. You can also ask Alexa about your home's current temperature, or what the temperature will be later in the day. Additionally, if you have multiple Nest thermostats in your home, you can control them all with Echo show. Just say "Alexa, turn down the heat in the bedroom."