Kava and Kratom extracts are both substances from plants; however, they have many differences based on origin, extraction method, active ingredients, and effects on the body. Kava is from the Piper methysticum plant, and its active ingredients are called kavalactones. Kratom is from the Mitragyna speciosa plant, and its active ingredients are mitragynine and 7-hydroxymitragynine. Kava is majorly known for its mild, relaxing effect;. However, Kratom also has a calming impact on users; it is more common to help block pain in users.