Hotels in Amsterdam city center are typically within walking distance or a short tram ride away from popular attractions. For example, the Anne Frank House is about a 15-minute walk from the city center, while the Van Gogh Museum and Rijksmuseum are around a 20-25 minute walk or a quick tram ride away. The distance can vary depending on the specific location of the hotel and the attraction in question, but in general, most hotels in the city center are conveniently located near popular sights.