For the 22LR pistol, 3 - 4 MOA seems to be a good balance for speed and accuracy at close range. For long-range rimfire shooting, the scopes require a bit more consideration. 8 MOA dot is most popular for shooting short-range like up to 4-15 yards especially with handguns or shotguns. The larger dot makes target acquisition quicker. The 1 - 3 MOA dot sizes are most popular with long guns for more pinpoint accuracy, as the smaller dot covers far less of the overall target area.