By plane Lesvos Island is located in the North Aegean. You can travel to Mitiline Airport (main city of Lesvos), by direct flight through Athens and Thessaloniki (Greek mainland) or from other European cities. By ferry You can come to Mytilene from the Greek ports of Piraeus and Kavala or from Turkey (Ayvalik).   Useful links: Mytilene airport: https://www.mjt-airport.gr/en/ Aegean Airlines: https://en.aegeanair.com/ Skyexpess Airlines: https://www.skyexpress.gr/en/ Skyscanner: https://www.skyscanner.net/ Hellenic Seaways: https://hellenicseaways.gr/en/ Ferry from Ayvalic: www.turyolonline.com