SIG-3 implements the standardization of genomic applications proposed at the NGS-CN. Our overall aim is to ensure the quality and reproducibility of generated NGS data regardless of the production site. The group promotes innovative solutions, proposes support for developing and evaluating new technologies, and organises the exchange of expertise and transfer of know-hows. The group also promotes the usage of laboratory management systems to control and harmonise collaborating production, and the standardization of project consulting for most popular NGS applications. Contact: nicolas.casadei@med.uni-tuebingen.de