A. Kale and kale chips are very safe to consume. But in very few cases, they show some potential side effects. It happens when the consumers have a kale allergy. For example, you may be allergic to kale if you are allergic to cruciferous vegetables. Kale is also a cruciferous vegetable. People should avoid kale consumption if they observe skin hives, itchy skin, swelling on lips and throat and gastrointestinal problems.