Generally, Belotero products are considered safe for the vast majority of patients. Talk to your provider and let them know if you have a history of severe allergies or suffer from multiple allergies. You may not be a good candidate for Belotero if you have an allergy to gram-positive bacterial proteins like peptidoglycan. This product is approved for adults aged 18 and older and is ideal for people with healthy immune systems. You cannot receive Belotero if you are pregnant or nursing.