While opinions differ, statistics never lie. The ByOwner website reveals where the most sales activity takes place in Charleston. As it turns out, the more popular neighborhoods are: Daniel Island, South Of Broad, Harleston Village, Carolina Bay, Ansonborough, Shadowmoss, Point Hope, North Central, Wagener Terrace, Oak Bluff, Grand Oaks Plantation, City Of Charleston, The Peninsula, Grand Bees, Lawton Bluff, Westside, Boltons Landing, Daniel Island Park, Wando Village, The Settlement.