Yes. I have made this cake as a layer cake, but also in a 13 by 9 pan with no issues. You will need to increase the cooking time to 32 to 35-ish minutes for a 13 by 9 pan. (Or until a toothpick inserted in the center comes out clean.) I have frosted the cake in the pan and have also flipped it out onto foil-covered cardboard and frosted it all the way around the cake. If you frost the cake in the pan, you will have leftover frosting. (The strawberry cream cheese frosting is great on toast or bagels!)