The optimal timing for taking CBD oil, whether on an empty stomach or after eating, depends on personal preference and desired effects. Taking CBD oil with food can slow down its absorption, potentially providing a more gradual and sustained effect. On the other hand, taking it on an empty stomach may result in quicker absorption, yielding more immediate effects. Experimentation is key to finding the preferred method, as individual responses vary. It's advisable to start with a small dose and observe how your body reacts, adjusting the timing based on your specific needs and how your body metabolizes CBD.