This group of diseases is caused when the motor nerves are damaged or affected causing the motor neurons to degenerate and die slowly. This leads to paralysis and this disease that has no cure is known as ALS or Lou Gehrig’s disease. The symptoms start very slowly such as weakness in the hands and legs, loss of grip and muscle cramps. Then they turn into breathing difficulty and issues in swallowing and loss of movement. There are no known causes and the one cause that is known is the genetic mutation. Most of the people with this disease die within 2-3 years after the diagnosis.