Nephrology related complications  such as acute kidney failure, advanced kidney damages and other conditions shows  some of the following symptoms Shortness in breathing Feeling tired or fatigue, dizziness Dizziness difficult sleeping or insomnia, sleep disturbances Itchy skin Certain muscle cramps Weight loss Poor appetite swollen ankles, feet or hands due to water retention which is often called oedema. Blood in urine Increased urinary regulation particularly during night. Feeling sick high blood pressure hypertension erectile dysfunction in men protein in the urine vomiting confusion trouble in concentration.