Most often, IUI is used for partners who fall into one of several categories. One category is partners who need to use donor sperm for pregnancy, and another is partners who can’t explain the issue they have with infertility. There are also partners with endometriosis-related infertility, semen allergy, mild male factor infertility (subfertility), cervical factor infertility, and ovulatory factor infertility. If any of those issues relates to your partnership, then there’s a good chance IUI will work for you.