Cured, hardened epoxy is not toxic. Overexposure to resins and curing agents used before the epoxy is cured may cause eye, nose, throat or skin irritation, as well as skin allergies and asthma.8  Exposure to solvent additives in epoxy resin systems can cause headaches, dizziness and confusion. Solvents inhaled or absorbed through your skin can also affect your central nervous system. Additional symptoms of solvent overexposure include slurred speech, confusion and loss of consciousness. Wearing PPE while working with epoxy resins can help minimize exposure and associated health effects.