The long-term effects of trypophobia are not fully understood, but some possible effects include: Avoidance behavior: People with trypophobia may avoid objects or situations that they know will trigger their symptoms. This can lead to social isolation and decreased quality of life. Anxiety and depression: Trypophobia can cause feelings of anxiety and depression. These feelings can be persistent and can interfere with daily life. Physical symptoms: Trypophobia can also cause physical symptoms, suc