The treatment of a urinary tract infection due to Escherichia coli is best done after a urine culture (and sensitivity) test. None of the antibiotics have an effect on fathering a child; however, females of childbearing age have to be careful of any medication during the first trimester. The details submitted by you are incomplete. You probably refer to Amikacin instead of Alkamine. The empirical choice of antibiotics for UTI are the fluoroquinolones (Norfloxacin, Ciprofloxacin or Ofloxacin) or Cephalosporins (Cefuroxime, Cephalexin or Cefixime). However, the choice of antibiotic guided by the sensitivity report gives better results, though there may be a clinical discordance between in-vivo and in-vitro effects.