Various drug interactions can make a birth control implant less effective at preventing pregnancy. In general, medications or herbal supplements that contain certain enzymes can decrease plasma concentrations in birth control implants, which reduces their effectiveness. Some of these medications and supplements include the following: • Anticonvulsants, such as phenytoin (Dilantin), carbamazepine (Tegretol), felbamate, oxcarbazepine (Trileptal), topiramate (Topamax), and rufinamide • Antifungal medications, such as griseofulvin (Grisovin) • Aprepitant (Emend), which helps with nausea and vomiting from chemotherapy • Barbiturates • Certain antibiotics, such as rifampicin (Rifampin) • Herbal supplements, such as St. John’s Wort • HIV/AIDs medications, such as efavirenz (Sustiva) • Medications for pulmonary artery hypertension, such as bosentan (Tracleer) For more information about birth control implant insertion and removal services or an appointment with us at Cobb Women’s Health, we would love to hear from you! Please feel free to reach out to us by calling us or scheduling an appointment with us right here on our website. You can find Cobb Women’s Health located at 1810 Mulkey Road, Suite 102, in Austell, Georgia. We serve patients from Austell GA, Lithia Springs GA, Mableton GA, Powder Springs GA, Douglasville GA, Fair Oaks GA, Hiram GA, Clarkdale GA, Smyrna GA, and Marietta GA.