There is a Tri-Sprintec Lo dosage for women who have a slight estrogen sensitivity. The pills are very similar, but the active pills in Tri-Lo-Sprintec have a little less estrogen. Women who use Tri-Sprintec but get mild estrogenic side effects may be recommended the “Lo” version by a doctor instead.
Estrogenic side effects are symptoms like nausea, swollen or tender breasts, or heavy menstrual bleeding.