Yes, sometimes a phone case can obstruct the GPS on your cell phone, leading to inaccurate location readings or no GPS functionality at all. To check if the phone case is causing the GPS problem, try removing the case and see if the GPS works fine. If the problem is fixed after removing the case, then you know that the case was the culprit. Consider investing in a case that doesn't obstruct the GPS or use the phone without a case altogether to avoid any further GPS issues.