There are several vitamins that play a role in maintaining energy levels, including: Vitamin B12: Vitamin B12 helps produce red blood cells, which are responsible for carrying oxygen to the body’s tissues. A deficiency in Vitamin B12 can lead to fatigue and weakness. This vitamin can be low in people with the MTRR or MTR polymorphisms. Vitamin B6: Vitamin B6 helps produce neurotransmitters, including serotonin and norepinephrine, which regulate mood and energy levels. Vitamin C: Vitamin C helps boost the immune system and reduce feelings of fatigue. Iron: Iron is a key component of hemoglobin, which helps transport oxygen in the blood. Anemia, a condition caused by a lack of iron, can lead to fatigue and weakness. Magnesium: Magnesium helps regulate energy metabolism and helps produce ATP, the body’s main source of energy. Folate: Folate works closely with B12 and is involved in making the precursors for cellular energy production, which gives your cells the necessary fuel to function. Without this, fatigue is a common symtpom. This vitamin can be low in people with the MTHFR polymorphism. In general, a balanced and nutritious diet that includes a variety of nutrient dense fruits, vegetables, lean proteins, and whole grains can help ensure that you get adequate amounts of these vitamins and minerals and maintain physical and mental health. If you are concerned about a specific vitamin deficiency, it’s best to consult a doctor to determine the best course of action.