Even if you’ve previously been infected with COVID-19 and recovered, experts recommend getting vaccinated. Your natural immune response may not be strong enough to protect you from future infections. If you were treated for COVID-19 with monoclonal antibodies or convalescent plasma, you should wait 90 days before getting a COVID-19 vaccine, according to the CDC. And if you currently have an active case of COVID-19, wait until after the isolation period is over to make your appointment to prevent spreading the virus at the vaccine site.