Sonablate HIFU is most effective for men who have early stage, localized prostate cancer that has not spread or metastasized outside the prostate. It is recommended that all men discuss individual medical records and history with a physician in order to confirm whether or not they are a candidate for HIFU. Sonablate HIFU is also an effective therapy for recurrent prostate cancer when patients may not have any other treatment options. Many patients who have had radiation therapy experience a rise in PSA and discover that the cancer has returned. These patients may be candidates for the HIFU treatment as well.