Yes, you can sew clear PVC, but there are a few things to keep in mind. First, because it's clear, any imperfections in your stitching will be visible, so take your time and make sure your stitches are even and straight. Second, because it's a plastic material, it can be slippery to work with, so you may want to use a walking foot or other type of stabilizer. And finally, be sure to use a needle designed for sewing plastics - either a universal or stretch needle - to avoid damaging the material.