Yes, individuals with sensitive skin should consider using hypoallergenic pillowcase materials to minimize irritation. Materials such as bamboo, silk, and specially treated hypoallergenic fabrics are advisable because they are softer and less likely to provoke skin reactions. Bamboo and silk, in particular, are naturally hypoallergenic and have smoother surfaces that reduce friction and irritation. Additionally, these materials are less likely to harbor bacteria and dust mites, common irritants for sensitive skin. Choosing the right pillowcase material can help alleviate discomfort and improve overall skin health for those with sensitive skin conditions.