The FDA-approved indication for Kybella is submental fullness. However, many people are beginning to use this product off-label to reduce small pockets of fat in different treatment areas. It has been administered to problem spots like the jowls, back (bra bulge), armpits, and knees.
Kybella has not been evaluated for safety or efficacy outside the submental area. Dr. Patel has had success treating jowl fat with Kybella. However, he still prefers to target the double chin.