Methylation (and therefore Biological Age measured by methylation) has been observed to change in response to a wide variety of factors. Even in the womb, our mother’s actions and habits influence our initial epigenetic patterns, and the choices we make throughout our life continue to change it. Some of the major factors include:  Nutrition (diet) Exercise Habits  Sleep habits Daily Stress  Psychological Trauma Social Relationships  Smoking Drinking Alcohol Medications Environmental pollutants Existing diseases And much more… Even long-term high altitude living has been found to make epigenetic changes!  Many ongoing research projects are focusing on the extent nutrition, exercise, medication, stress, and sleep can change methylation, since those have already been confirmed as major influencers, and are things the average person can control.