Here are the interesting tips to stop an inflated balloon to deflate! Have a look! 1) Mist of any setting spray that is used for hair works amazingly to stop a balloon from stopping. 2) Store the inflated balloons in a large plastic bag so that they will stay safe from blasting off. 3) Pinch the neck of the balloon using binder or paper clips but it is less effective. You need to secure it tightly otherwise the balloon may deflate.