The Six Sigma approach in Business Process Re-engineering (BPR) is a strategy for improving the quality of outputs in a business process. It identifies and mitigates defects and minimizes process variability. Six Sigma is often aligned with Design for Six Sigma (DFSS) in BPR for designing a new process or radically redesigning an existing one to meet customer needs.
In the real-world application of Six Sigma to BPR, the DMAIC methodology (Define, Measure, Analyze, Improve, Control) is often used in tandem with traditional BPR efforts.