It is important to note that individuals can have different reactions to medications, including methylphenidate, which is commonly prescribed for Attention Deficit Hyperactivity Disorder (ADHD). There are reports of mood changes, including depression, in some individuals taking methylphenidate. However, it's also possible that some people who take methylphenidate have underlying mood disorders that may be unmasked by the medication. It's important to communicate with a healthcare provider if you or someone you know is experiencing new or worsening mood symptoms while taking methylphenidate or any other medication. A healthcare provider can offer the best guidance and options for managing side effects and assessing whether a medication is appropriate for an individual's specific situation. Please consult a medical professional for personalized advice and information on this topic.