Most, if not all, of the signatories of the Pact already operate by the commitments in the Pact. However, we believe in the added value of a collective, formal declaration by a broad group of companies to stimulate important dialogue which has been lacking for some time. The principles may sound obvious, but they have not necessarily always been applied as a rule, or at least it hasn’t been perceived as such. Mutual trust is a fundamental and necessary component within any relationship if solutions are to be found but particularly so in such a high-stakes relationship as that between the pharmaceutical industry, healthcare authorities and the public. Our objective is to establish an engagement platform, which we will use to contribute to the emergence of a shared vision on how to adapt our healthcare systems to the challenges of the life sciences revolution.