No, Nucoril OD 5mg Tablet does not affect your sex life. However, it is not recommended to take medicines used to treat erectile dysfunction (e.g., sildenafil or tadalafil) or premature ejaculation (e.g., vardenafil or dapoxetine) while taking Nucoril OD 5mg Tablet. Taking them together can lead to a serious drop in your blood pressure.