The results of BOTOX don’t last forever, but they can endure for several months. When you begin to see your wrinkles reappearing, you may return to our office for a touch-up treatment. BOTOX has been proven to be safe for long-term use. On the other hand, there’s no rule that says you must have a touch-up. You may choose to leave your skin as-is, undergo treatment with injectable fillers, or even consult for a facelift for an even more significant result.