We do know that a family history of endometrial (or uterine) cancer (along with breast, ovarian and colorectal) can put someone at increased risk for ovarian cancer. As to whether prophylactic removal of one’s fallopian tubes reduces the risk for endometrial/uterine cancer, that has not been indicated. However, studies have shown that the use of combination oral contraceptives (with estrogen and progesterone) can lower the risk of endometrial cancer, as well as ovarian cancer. And progesterone IUDs also reduce risk for endometrial cancer.  It is important to note that just like ovarian cancer, endometrial cancer is an umbrella term that includes subtypes, each with varying points of origin, treatment methods and disease trajectories.