Dr. Otto Octavius, also known as Doctor Octopus or Doc Ock, was a nuclear scientist. During an experiment, a volatile explosion occurred, causing him to be bombarded with radiation. This accident resulted in his mechanical tentacles, which he initially designed to manipulate radioactive substances from a safe distance, becoming fused to his body. The radiation also gave him the ability to mentally control these tentacles. However, the incident caused irreversible brain damage, transforming the respected scientist into a megalomaniacal superhuman criminal known as Doctor Octopus.