Hyperlite packs are made to increase comfort. Their focus is on reducing the weight that you carry in order to increase comfort, and for some people, that’s all it takes. It isn’t necessarily going to be more comfortable due to the pack design, but it will ensure that you have less weight on your back.
So, it’s all up to you. Everyone’s bodies are different. Hyperlite uses a small amount of padding on the belts and straps, meaning it may not be the most comfortable for everyone, but some people prefer the tighter fit.