Heartburn may be a symptom of several concerning health issues and should be reviewed by a healthcare practitioner. It is important to consult one of our doctors if: You find it hard to swallow. You have frequent bouts of vomiting. You experience unexplained weight loss. Your heartburn occurs two or more times over the course of a week. The discomfort of heartburn is extreme or occurs alongside other symptoms. Nonprescription medications do not improve your symptoms.