If you are sensitive to latex, do not handle the SureClick Autoinjector, Enbrel Mini single-dose prefilled cartridge, or the prefilled syringe. The needle cover of the prefilled syringe, needle cover within the white cap of the SureClick Autoinjector, and needle cover within the purple cap of the Enbrel Mini single-dose prefilled cartridge are made of dry natural rubber (which comes from latex). Talk to your doctor about the best injection method for you.