If you have a history of migraine headaches, you should be particularly concerned about any new or unusual headache symptoms that you experience. In general, you should seek medical attention if you have a headache that is severe, sudden, or accompanied by other symptoms like fever, confusion, weakness, or numbness. These symptoms could indicate a more serious condition, such as a stroke, meningitis, or a brain tumor. If you experience any of these symptoms, it's important to seek medical attention right away.