Yes, you can crop an irregular shape in Photoshop by pressing the F7 key to launch Photoshop's layers panel. Double-click on the lock icon to unlock the layer, right-click on the Lasso icon on the tools panel, and then click the polygonal lasso tool. Outline the shape and then double-click on it to select it. Press the Shift + F7 key to choose the inverse of the shape. Press Backspace to make the selected area transparent while cropping the photo to an irregular shape.