Complex regional pain syndrome (CRPS) and reflex sympathetic dystrophy (RSD) are terms used to describe a localized form of amplified musculoskeletal pain syndrome. Children and adults with localized amplified pain typically have pain and increased sensitivity to touch in one or more limbs, although any part of the body may be involved, and the pain may move from one area to another. Some people with CRPS/RSD also have coolness or color change of the affected area.