Yes, you can listen to hi-res audio players wirelessly, but keep in mind that Bluetooth traditionally compresses audio. Newer codecs like LDAC and aptX HD improve wireless sound quality, so for the best experience, you'll need a hi-res audio player and Bluetooth headphones that support these codecs.
That said, some audiophiles argue that even the best wireless setups can’t fully match the sound quality of a wired connection, especially when dealing with high-resolution files.