Opening NFL Week 1 Odds and Lines GameSpreadMoneyline 49ers at Steelers49ers -3.049ers -145, Steelers +136 Cardinals at CommandersCommanders -5.5Cardinals +198, Commanders -215 Packers at BearsBears -1.5Packers +115, Bears -120 Raiders at BroncosBroncos -3.0Raiders +150, Broncos -172 12 more rows