If coolant spills on your car floor or seats, it can create a hazardous situation. Coolant is toxic and can cause skin irritation, eye damage, and respiratory problems if inhaled. If you come in contact with the coolant, it can be absorbed through your skin, and if ingested, it can be fatal. You should not attempt to clean up coolant spills yourself, as it requires proper protective equipment and disposal. It is best to seek professional help to clean up the spill and prevent any health risks.