Children and young adults today are significantly more likely to experience mental health problems—especially anxiety and depression—than in decades past, and many will require mental health interventions at school. Evidence suggests that schools of any level can best support and help treat students with mental health disorders by proactively identifying students who need help, fostering a school culture that makes mental well-being a priority, and working to decrease stigma surrounding mental health care, both among students and their families. For students without diagnosable mental illnesses, schools can still be supportive by ensuring workloads are reasonable; providing opportunities for movement, creativity, and social connection; and reminding children, teenagers, and young adults that it's OK to ask for help.