The two are close cocktail cousins, but the Painkiller is served on the rocks and includes fresh orange juice and dark rum. A piña colada, however, is served frozen with no orange juice. The base is typically a white rum, though it’s often served with a dark rum floater for an extra bit of fun. Despite their differences, if you enjoy a piña colada, I bet you’ll equally love this Painkiller tiki drink.