Exercise affects endorphins, cortisol, and insulin. Exercise reduces stress through regulating cortisol. Exercise releases endorphins, the "feel-good" chemicals, which cause "runner's high." Endorphins boost happiness and well-being. Exercise increases insulin sensitivity, making blood sugar management simpler. Increased insulin sensitivity helps diabetics and others at risk maintain stable blood sugar levels. Exercise reduces stress, boosts mood, and improves metabolic regulation due to these hormones' intricate interactions.