You never want to submerge your headphones in water, but it is ok to spot clean them with rubbing alcohol or hand sanitizer. It’s best to keep dust and ear wax (hey, it happens) out of your earbuds, as well. To remove things like this, grab a Q-tip and some rubbing alcohol and brush it over the mesh wiring of your speaker. Never stick anything into the actual speaker, or you’ll risk damaging your headphones.