Answer — Yes, and not just by creating next-generation vaccines designed to target the variant strains. Many different ways of using current vaccines to help best protect against COVID-19 are also being investigated These include additional booster dose(s) of vaccines; higher doses of vaccines; and possibly even mixing vaccine types to expand effectiveness and/or durability of COVID-19 vaccines that are not identical. It should also be emphasized these concepts are only experimental at the present time, and not currently approved or recommended.