A buffalo hump is a condition characterized by a buildup of fat deposits at the back of the neck, typically at the shoulder level, forming a noticeable hump. Its appearance resembles the hump found on a buffalo, hence the term 'buffalo hump.'A buffalo hump is a condition characterized by a buildup of fat deposits at the back of the neck, typically at the shoulder level, forming a noticeable hump. Its appearance resembles the hump found on a buffalo, hence the term 'buffalo hump.'