We recommend roasting the asparagus for 10-12 minutes at 350° Farenheit. However, asparagus can be cooked in the oven anywhere from 350° to 425° F, the time ranging from 8 to 20 minutes. Because asparagus grows at different thicknesses, a safe bet is to check your asparagus after 8-10 minutes. The asparagus is done if you can easily pierce the thickest part with a fork.