Variables such as starting weight, diet, exercise routine, and underlying medical conditions affect how long the body resists weight loss. The body typically resists weight loss for a few weeks to several months. Furthermore, weight loss resistance can be caused by underlying medical conditions or medications. In some cases, genetic factors also play a role. Due to water weight loss, individuals often experience rapid weight loss when beginning a weight loss program. After this initial phase, weight loss may slow or plateau. After this, the body may resist further weight loss. This commonly occurs as a result of metabolic adaptations, in which the body reduces its metabolic rate in response to a lower calorie intake. This adaptation makes it harder to burn calories and lose weight. Losing weight is a gradual process that requires consistency and patience. Making healthy lifestyle choices, such as maintaining a balanced diet, regularly exercising, sleeping well, and controlling stress, can support weight loss efforts and help you overcome weight loss resistance. If you're still having trouble losing weight despite your best efforts, talking to a weight loss specialist is recommended.