Combined pills such as Microgynon 30 have been shown to help with acne for some people. This is due to the active ingredients which can regulate androgen levels and reduce the amount of sebum you produce. Sebum is an oily substance that can protect and hydrate your skin. In people with acne, too much sebum is produced, causing hair follicles in the skin to become blocked, forming spots.  It may take 6 to 12 weeks to see an improvement in your acne if you take Microgynon. It takes time for your body to adjust to the hormones in the pill, and during this time, your acne could be worse. If your acne doesn’t improve after using Microgynon for several months, speak to your doctor.