Most headboards and footboards can be used with an adjustable base. However, you may need to make some adjustments. In most cases, the legs of an adjustable base will replace the wood slats and traditional box spring to be positioned inside the existing bed frame. A zero-clearance adjustable base will be your best option if you have a platform bed with its own foundation or no box foundation. The same will apply if you have storage or drawers built into your bed frame.