The permanent teeth erupt at different times during adolescence. For instance, the upper teeth’s first two premolars (first bicuspids) usually erupt at 10 or 11 years old. The first two premolars in the lower teeth erupt between 10 and 12 years old. In many cases, the final permanent teeth to erupt are the wisdom teeth, which usually happens between 17 to 21 years old. This is why wisdom tooth removal often takes place at these ages.