One of the most common questions we get during Thanksgiving is why does my turkey meatloaf fall apart. There are a few things that could be causing this, so let's break it down. One possibility is that you're not using enough binding agent. When you make meatloaf, you need some kind of binding agent to help hold everything together. This could be eggs, breadcrumbs, or even oatmeal. If you're not using one of these ingredients, your meatloaf is more likely to fall apart. Another possibility is that you're overcooking your meatloaf. Turkey is a leaner meat than beef, so it's more susceptible to drying out. If you cook your meatloaf for too long, it will start to fall apart. Finally, it's possible that you simply don't have enough fat in your recipe. Fat helps to bind the ingredients together and keeps the meat moist. If you're using lean ground turkey, you may need to add some additional fat to your recipe. This could be in the form of olive oil, bacon grease, or even cream cheese.