You can and it is also very common to combine other cosmetic dermal fillers - such as Juvederm - with Sculptra injections. Unlike dermal fillers, Botox is a neuromodulator and works by relaxing the muscles of facial expression, mostly in the forehead and around the eyes. Sculptra is not typically used in these areas. It is a deep injection that aims to contour the jaw area, jowls, cheeks, and other areas of volume loss and wrinkles.