The Direct Coombs' Test (Direct Anti-globulin Test, DAT) is usually done to diagnose immune haemolytic anaemia, a type of anaemia where the red cells are destroyed due to antibodies attaching to them. This may be secondary to an auto-immune disease, some medicines, infections, diseases etc. A positive test result means that antibodies are bound to the red cells. The stronger or more positive the test, greater is the amount of bound antibodies.
A positive test result needs to be correlated with your symptoms and clinical findings so that the cause can be found. The test can also be positive in a small proportion of normal healthy individuals. Please discuss with your doctor and do not worry unnecessarily.