How you clean your dirty garden gloves depends on what type of gloves they are and what they are made of. Basic cleaning can be done with soap and water or even spot cleaning with a small brush. Leather gloves should be cleaned with saddle soap, and a damp cloth or paper towel. Leather should be cleaned in small circular motions a little at a time without fully submerging under the water and, once dry, leather gloves can be treated with leather oils. It is recommended that all gloves be air-dried to prevent shrinkage.