In ancient times, Chinese, South American, and Egyptian civilizations all used vegetable, mineral and skin grafting to treat wounds. In the early 1800s, scientists revealed all life depends on chemical reactions within cells and could be reproduced in the lab. In the early 1900s, scientists discovered DNA and its impact on cell division and subsequently were able to reproduce this phenomena in labs. In the mid 1900s organ transplantation, surgical implants and bio-materials led to the ability to grow and harvest tissues for therapeutic use, hence the birth of the field we now call regenerative medicine. Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-biotherapeutics/about