The simple answer is: yes, Ultram can cause a person to experience a high. Taking Ultram can induce a feeling of euphoria. Taking a higher dose than what is prescribed, injecting or snorting the drug, or taking the drug with other substances like alcohol can increase the feeling of euphoria that people feel. However, this high is also associated with increased risk for overdose, which can have life-threatening results. When taking the drug as directed, people are unlikely to feel high. In fact, less than one percent of people who are prescribed this drug and take it in accordance with their doctor’s instructions report feeling high after taking it.