Yes, they can be strapped in a car to the seat of the car, but it is best to use proper car seats specially made for infants to ride in the car. These seats do not have all of the safety features that regular car seat do with the straps and harnesses plus the hard shell to protect the baby’s body in case of a crash. It is best to just use these floor seats indoors or outdoors, such as at a picnic. Car seats are best for infants in the car.