Hi, Yes, research studies do show that few people do get heart problems after taking small pox vaccination. Few deaths have also been reported. Presently if you have tightness in the chest associated with breathlessness it could be angina. As such angina is not a disease but is caused by low oxygen in the blood reaching the heart. However, angina can be indicative of some serious developing coronary artery disease. You can take sublingual Nitrogycerine when you feel tightness in the chest after consultation with your treating doctor. Do not neglect yourself, visit a cardiologist, get physically examined & get all screening tests done to rule out any CAD. The tests will include CBC, Urinalysis, lipid function tests, X-ray, ECG, Echocardiography, Stress tests & CT or MRI if required. Get treated. In the meantime, stop addictions if any, avoid taking red meat, oily-spicy food. Take low carbohydrate, boiled home made food, fruits & veggies. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Nupur K, General & Family Physician