Unfortunately, back pain if you take Xarelto is often indicative of a deeper problem. It could be a sign of spinal blood clots. However, most people who experience back pain on Xarelto also have the following risk factors present. Spinal taps or a spinal puncture Having a spinal catheter Genetic spinal defects A history of spinal surgery You take other drugs that could cause a blood clot. Spinal blood clots can also cause muscle weakness and even numbness in the body. If you experience these symptoms or incontinence after stopping a blood thinner, call your doctor immediately.