Yes, Mac computers can open BitLocker USB drives. To access the files on a BitLocker-protected USB drive, you will need to install the appropriate software for your operating system. For Mac users, you will need to install Microsoft's BitLocker To Go Reader software from the Mac App Store. Once installed, plug in the USB drive and it should be detected by your computer. You will then be prompted to enter the encryption key associated with that drive in order to unlock and access its contents.