No, you can’t – as long as you diligently keep Flash Player up to date and all the new versions are installed from the official source. In a vast majority of incidents where this utility is exploited to deposit malware onto Macs, the victims neglect the update hygiene and use very old versions of the product with multiple unpatched security loopholes in them. Flash updates pushed via popup alerts on rogue websites are a completely different story. The installation clients in this case include bundled malware. If you happen to opt for this kind of an offer, a contamination is pretty much inevitable. The article above highlights the common infection scenarios through fake Adobe Flash Player update notifications. Note that Mac users are typically redirected to these landing pages because their browsers have been hijacked. Therefore, removal of the underlying virus is a prerequisite of addressing the predicament.