The solution to the Node.js vs. Python dilemma depends on the specific type of software you want to create. Node.js is a good option for data-intensive projects that do not require too much code. At the same time, if you want to build complex applications with lots of integrations, Python is a preferred option. Besides, you should know that Python is not good for scalable projects. In this regard, Node.js gets the upper hand. Finally, unlike Node.js, Python does not work well for mobile application development.