In all honesty, it depends on different factors. For example, time. In the nineties and early 2000s, one of the most famous European women was Naomi Campbell. At some point, one of the most famous European women was Kira Nightly. If we don't talk about celebrities, but about politics, then Margareth Thatcher is definitely one of the most memorable European women. Moreover, it's hard to choose just one woman since there are many accomplished European ladies from different countries.