Signs of a spider infestation in your Tuscaloosa basement may include the presence of webs, egg sacs, and actual spiders themselves. Spiders tend to hide in dark, undisturbed areas, so check corners, crevices, and behind stored items for signs of activity. While most spiders are harmless, some species like the brown recluse and black widow can pose health risks, so it's essential to address infestations promptly.