Process controls and environmental controls must also be in place to ensure repeatability between trials; between individual studies for compounds required multiple studies and between studies days for multiple dose day studies. Maintaining consistent temperature, pressure, and humidity within the exposure environment is essential. Changes in model loading methods and the ambient environment can also impact the study's results. Maintaining the necessary levels of consistency can be challenging, especially for 24/7, whole-body exposure dose studies. Here at AmplifyBio, we have the ability and controls to mitigate these issues.