Immunotherapy is a treatment approach that helps stimulate the body's immune system to recognize and attack cancer cells. It has shown promising results in some cases of advanced mouth cancer. Immunotherapy drugs, such as immune checkpoint inhibitors, can help block the mechanisms that cancer cells use to evade immune detection. However, not all patients will benefit from immunotherapy, and its use depends on several factors. Consultation with an oncologist is crucial to determine the suitability of immunotherapy in individual cases.