Both Cequa and Restasis are eye drops that contain cyclosporine. They are used to increase tear production in patients with dry eye disease (medically called keratoconjunctivitis sicca). However, Cequa incorporates a novel nanomicellar technology of cyclosporine A to allow delivery of high concentrations of the medication into the eye. Restasis is not manufactured using nanomicellar technology. Nanomicellar technology can help deliver poorly water-soluble drugs into the eye and protect the drug molecule.