Although it is rare, the uncooked flour in cake mix can cause food-borne illness. Heating the raw cake mix until it reaches 165°F on an u003ca href=u0022https://amzn.to/3r9boxXu0022 target=u0022_blanku0022 rel=u0022noreferrer noopener nofollowu0022u003einstant-read thermometeru003c/au003e ensures that it can be enjoyed safely.