Vo filme Niť z prízrakov hrajú Daniel Day-Lewis (Reynolds Woodcock), Vicky Krieps (Alma Elson), Lesley Manville (Cyril Woodcock), Camilla Rutherford (Johanna), Gina McKee (Countess Henrietta Harding), Brian Gleeson (Dr. Robert Hardy), Harriet Sansom Harris (Barbara Rose), Lujza Richter (Princess Mona Braganza), Julia Davisová (Lady Baltimore), Julie Vollono (London Housekeeper), Sue Clark (Biddy), Joan Brown (Nana), Harriet Leitch (Pippa), Dinah Nicholson (Elsa), Julie Duck (Irma), Maryanne Frost (Winn), Elli Banks (Elli), Amy Cunningham (Mabel), Amber Brabant (Amber), Geneva Corlett (Geneva), Juliet Glaves (Florist), Philip Franks (Peter Martin), Tony Hansford (Petrol Station Owner), Steven F. Thompson (Maitre'D), George Glasgow (Nigel Cheddar-Goode), Niki Angus-Campbell (Young Fan), Georgia Kemball (Young Fan's Friend), Nick Ashley (Charles Gayford), Ingrid Sophie Schram (House Model), Ellie Blackwell (House Model), Zarene Dallas (House Model), Pauline Moriarty (Minetta), Eric Sigmundsson (Cal Rose), Phyllis MacMahon (Tippy), Richard Graham (George Riley, News of the World), Silas Carson (Rubio Gurrerro), Martin Dew (John Evans, Daily Mail), James Thomson (Reporter), Tim Ahern (Barbara's Lawyer), Leopoldine Hugo (Princess Mona's Mother), Delia Remy (Bridesmaid), Alice Grenier (Bridesmaid), Emma Clandon (Reynolds' Mother), Ian Harrod (Registrar), Sarah Lamesch (Steff), Nicholas Mander (Lord Baltimore), Jordon Stevens (Lady Baltimore's Daughter), Michael Stevenson (MC, New Year's Eve Party), Jane Perry (Mrs. Vaughan), Charlotte Melen (Young Fashionable Woman), Dave Simon (Chelsea Arts Club New Years Eve Party Guest (uncredited)), David Charles-Cully (Chelsea Arts Club New Years Eve Party Guest (uncredited)), Louis Hannan (Chelsea Arts Club New Years Eve Party Guest (uncredited)), Evie Wray (Wedding Guest / Dancer (uncredited)), Jonathan Wayre (Pathe News Cameraman (uncredited)), Cécile van Dijk (Cécile (uncredited)), Jack Tyson (New Year's Eve Party Guest (uncredited)), Joshua Tomkins (New Year's carnival Float Team Cowboy (uncredited)).