It can! Alcohol is a depressant that lowers serotonin levels in the brain, which causes diminished mood and increased levels of anxiety and depression. It's why you feel \\"blah\\" or lazy the day after drinking heavily. Drinking more than (an average) one drink per day, or seven drinks per week, experience higher baseline stress levels, reduced ability to handle stress, and diminished mood. The combined effect can greatly damage your happiness and motivation levels.