Adderall is a brand-name prescription medication that contains amphetamine salts, which work as central nervous stimulants in the brain and body. Stimulants are drugs that increase activity in the central nervous system to promote wakefulness, focus, and energy. Adderall works with a naturally occurring chemical in the brain called dopamine, and this chemical is tied to reward, motivation, and pleasure. People with ADHD are thought to have low levels of ambient dopamine in the brain, which would normally keep them satisfied and focused as they complete daily tasks. Having low levels of dopamine can cause the brain to seek other sources of reward while a person tries to focus on tasks. This can make distractions extremely hard to resist. Adderall increases dopamine levels in the brain by blocking a process called reuptake. This process is designed to remove chemicals from the synapse and recycle their material. Blocking the reuptake of dopamine causes it to build up in the brain, making the effects of the natural chemical more potent. People with ADHD can get relief from their symptoms because Adderall will increase the levels of ambient dopamine in the brain, making it easier to focus and sit still. Adderall can also increase blood pressure and wakefulness, which can be helpful for people who have sleep disorders like narcolepsy. However, like caffeine, the period when Adderall starts to wear off can cause uncomfortable comedown symptoms followed by a crash. This is a result of shifting chemical balances in the brain. As the stimulating effects wear off, it can leave users tired and unfocused.