There is no one-size-fits-all answer to this question, as the best software to prevent hackers will vary depending on the specific needs of the organization in question. However, some common software solutions used to prevent hacking include firewalls, intrusion detection and prevention systems, and anti-virus and anti-malware programs. In addition, it is important to keep all software and systems up to date with the latest security patches to help prevent hackers from exploiting known vulnerabilities.