Beyond gestational age, other factors that may contribute to the risk of life-threatening disease in infants with skin lesions include the presence of comorbidities, immune status, and the overall health of the infant. Infants with underlying medical conditions or compromised immune systems may be at a higher risk of developing severe infections. Additionally, environmental factors, such as exposure to pathogens or inadequate hygiene practices, can also play a role in increasing the risk of life-threatening diseases in infants with skin lesions. Healthcare providers should consider these factors when evaluating and managing infants with skin lesions to ensure appropriate care and timely intervention.