Zipfizz is unlikely to spike insulin levels. Despite containing sweeteners, it's low in carbohydrates with only 2g per serving. Stevia doesn't impact blood sugar. The erythritol may raise insulin slightly but not significantly. For those with diabetes or insulin resistance, Zipfizz won't create the blood sugar spike and crash of sugary sports drinks. The caffeine may indirectly raise insulin slightly due to enhancing metabolism. But overall, Zipfizz isn't an insulin-spiking beverage.