Yes. A transactional change helps ensure that the change is consistent, reliable, and independent of other changes. Amazon Route 53 has been designed so that changes complete entirely on any individual DNS server, or not at all. This helps ensure your DNS queries are always answered consistently, which is important when making changes such as flipping between destination servers. When using the API, each call to ChangeResourceRecordSets returns an identifier that can be used to track the status of the change. Once the status is reported as INSYNC, your change has been performed on all of the Route 53 DNS servers.