There are two things to consider for patients who are mobile: 1) data accuracy, 2) device adherence. The most common impact is signal quality. This depends on how much movement there is, the modality or location of the wearable, and the type of data you’re trying to capture. For example, ECG signals can be noisy with high activity. But if you just want heart rate, there are many devices which can measure an accurate heart rate even with movement. The other issue has to do with whether the device will stay securely on the body. You’ll want to choose devices that won’t shift easily (which affects signal quality), and won’t fall off with movement. Also consider nighttime readings since some people move quite a bit during sleep. Note also that with adhesives based devices, heavy sweat or humidity can affect how well it adheres to the body.