All the human clinical trials on resveratrol and NMN have been conducted individually. Therefore, it is not entirely clear whether there is any positive synergistic effect between these two molecules when taken together. Most of our customers choose to take them together, either in the same meal or on an empty stomach when they are still in a fasted state. People opt to combine them based on David Sinclair's statement that these two would work better when taken together. However, there is no clinical trial evidence to support this, but I personally prefer to take them together.