No. The area code, just like the physical location of your business, is entirely up to you. The two can be in entirely separate time zones. Some of the more popular area codes to choose from include 202, 213, 267, 281, 302, 310, 330, 347, 404, 425, 510, 512, 630, 646, 703, 732, 805, 817, 818, 916, 925 and 949.