Yes! Most major insurance companies cover Spravato esketamine nasal treatment for depression. Currently, esketamine treatment is approved for people with treatment-resistant depression. That means you've tried at least two other antidepressants (for at least six weeks each) and haven't experienced remission or at least a 50% improvement in mood. Our caring clinic staff will work with your insurance provider to handle all the insurance on your behalf. Your out-of-pocket cost will depend on your specific insurance co-pay, but thanks to Spravato savings programs, you may pay as little as $10 per treatment.