No, Jojoba oil does not cause eczema. Although jojoba oil is believed to be the cause of certain conditions like a rash or allergic reactions and in some extreme cases, for example, when Jojoba oil is taken through the mouth, it can lead to heart damage because of the erucic acid in its composition. However, applying Jojoba oil to your hair will never lead to eczema, but rather, it can prevent it from ever occurring. The liquid wax of Jojo oil on application keeps the skin moisturized thereby preventing dry itchy patches, a sign of eczema.