Granulomas are inflammatory reactions that can occur with all fillers, including Juvederm and Restylane.  They are easily treated. Bellafill was studied in the longest and largest filler safety study ever conducted.  The granuloma rate was a mere 1.7% in this study.   The majority of lumps or “granulomas” resolve on their own with a very few needing to be treated with a small injection of low dose Kenalog or steroid.