Yes, Romana Sambuca is gluten-free, as are most other sambucas. The ingredients that go into sambuca include spices, anise, licorice, and elderflowers, delivering a beverage that is unique and flavorful — as you would expect from a wildly popular liqueur imported straight from Italy. This liqueur is a good choice for those with celiac disease or gluten sensitivity, offering a flavor you won’t forget and a finish as smooth as the bottle.