Iron stain is the discoloration of the skin in the region of the lower leg and ankle area related to long term venous hypertension and the leaking of red blood cells out of the veins into the skin where the pigment is then released causing pigment deposition in the skin. Over time, white blood cells may also leak out and cause further damage to the skin resulting in hardening and scarring of the tissue. The eventual result is a minor traumas leading to an opening in the skin which turns into a “venous ulcer”. Treatment of the underlying cause of the venous hypertension (sealing of the leaking vein) will stop further progression of the changes and with time, as new skin cells replace the older, diseased and pigmented cells, the changes will begin to reverse, sometimes completely.