Many thanks for your email and my sincere condolences on the bereavement in the family. Urokinase is a clot busting drug and is used after angioplasty, either to disolve a clot or to prevent a clot from forming in the stented or angioplastied arteries. Untoward reactions to drugs are known, but I am not in a position to give any further comments on your father in-law’s case as I would need much more clinical details before I can give an opinion on this matter.