De-sexing a dog exposes a dog to a risk. The risk of an operation is not negligible. Any operation that involves using full anesthesia should be undertaken with enough knowledge of what could happen. Some breeds of dogs are more sensitive to anesthesia than others. Greyhounds and herding dogs have a genetic sensitivity to anesthesia and require special monitoring. Evidence indicates that neutering may raise the lifetime risk of a dog to serious medical issues particularly various types of cancer. Also, particular breeds have been found to have their own breed-specific health risks. For example, altered Golden Retrievers have a higher incidence of hypothyroidism.