It is believed that the frequencies work on the principle of biological resonance. A singer can shatter a glass when the note resonates with the crystal structure of the glass. Microcurrent frequencies seem to be able to resonate with biological tissue when the frequency is correct. Once the tissue is changed and stable, it seems to be able to stay in the new configuration with proper nutritional support. Research confirms that the frequency for inflammation reduces inflammation by 62% in a mouse model while prescription drugs reduce inflammation by 45% in the same mouse research.