No - never ever use human insect repellent on dogs. Most Off! products and human insect repellents use DEET as their main ingredient. DEET is toxic to dogs and can cause vomiting, irritation, seizures and even death in some cases. Note: Picaridin is another common ingredient in most human insect repellents. Most research has indicated that Picaridin is generally safe for dog use but - hey I'm not a vet - do your own due diligence and decide if you're comfortable using this on your pup. Personally, I'd really only use it on a dog's clothing or external items instead of directly on my dog's fur since Limone does have a habit of occasionally licking herself all over and I'd love to avoid a sick dog as much as possible.