Spybot Search & Destroy works with the latest version of Windows 10. I also tested Spybot Search & Destroy on a Windows 11 computer and had no problems running it. However, that doesn’t necessarily mean Spybot is a good choice. It lacks many features you’d expect in an antivirus in 2024, including good malware detection rates and decent additional security features.
If you want a good antivirus that’s compatible with both Windows 10 and 11, you should check out our list of best Windows antiviruses in 2024. Every antivirus on this list works better than Spybot Search & Destroy.