Residential wasp spray in cans is quite affordable. You can expect to pay between $4 and $10 for a single can with a standard pesticide formula. If you need a stronger spray for a stubborn wasp infestation, you’ll pay about $20 to $30 per can. Multipacks containing two to a dozen cans will save you some money. Concentrated commercial formulas cost between $30 and $40 for a bottle that makes 30 to 40 gallons of spray.