Yes, you can use Phexxi if you’re using other vaginal medications.Phexxi comes as a gel inside single-use, prefilled applicators. Using one of these applicators, you insert the gel into your vagina. You can do this right before sex or within 1 hour before sex.Using Phexxi can raise your risk for several types of infections, such as yeast infection. (For more information, see the “Phexxi side effects” section above.) These infections may be treated with other medications that are inserted into the vagina. Examples of these drugs include:miconazole (Monistat)metronidazole (Metrogel)tioconazole (Vagistat)You can still use Phexxi if you’re using other vaginal medications. If you have questions about using Phexxi with other vaginal drugs, talk with your doctor or pharmacist.