Maybe, this depends on how much you’re selling and where.
These days there are many places that tax online sellers, and the US is no different. More states are added to the list every year. In these states, you must charge sales tax for online transactions only if your annual sales exceed the economic nexus threshold. See question above!
Once you have economic nexus in the state, you’re legally required to register for sales tax.
You might not need to charge sales tax if a buyer has a tax exemption certificate. You also might not need to charge sales tax if you’re selling on or through an online marketplace that is covered by marketplace facilitator tax laws in that state.
Learn more about how to comply with sales tax.