The effects of puberty blockers are reversible. As for hormone therapy, it often depends on how long you’ve been on the treatments. For example, if you start growing facial hair and developing a deeper voice while taking testosterone, that may not go away. “But most of the rest of the impact of testosterone is reversible, especially at those younger ages, including male pattern baldness and shifts to fertility,” says Safer. Often, says Rafferty, when a patient decides to stop taking hormones, it’s not because they hope to revert to the gender they were assigned at birth, but because they identify as nonbinary. “Some of those more permanent effects of testosterone are not something that necessarily they see as sort of detrimental or negative.  He adds, “I always tell my patients it’s not like one day you make a decision, [and] you have to live with it. You make this decision every time you come to the clinic. We want to know if something doesn’t feel right, and we will work with you to correct that whether it’s your first day in clinic, or whether that’s 10 years in clinic.”  Mel says, “If it’s right for you to transition, it feels right.” For more information about transgender care, check out guidelines from the University of California San Francisco and the Endocrine Society. For a more in-depth discussion of mental health in regards to transgender identity and transition, check out reporting from undark.org.