The amount of time it takes for an insect to die will depend on the species of insect. Some, like sugar ants, will die almost instantly whereas cockroaches can take up to a minute to die, because of their hard protective exterior. If an insect has a hard exterior or hair on their body it may take longer for Six Feet Under to permeate their body, but rest assured: it will still kill them.* *Please note: spiders are NOT insects. Due to their physiological design, Six Feet Under is not as effective on spiders and other arachnids. It can take up to 10 minutes to affect some species.