CMYK and PMS colors produce distinct results. CMYK creates a wide range of colors by blending tiny dots of cyan, magenta, yellow, and black inks, making it ideal for complex, multi-colored designs. In contrast, PMS uses pre-mixed inks to precisely match specific colors, ensuring exact color consistency. For your folders, choose CMYK for intricate designs and images, and PMS for precise color matching, such as logos or branding depending on whether color precision or creative flexibility is your top priority.