It is not required to remove your partial dentures when you sleep. However, if you are comfortable doing so, it is highly recommended to give your gums a rest. Wearing your partial dentures to sleep all the time may cause gum sores and inflammation. It may also shorten the lifespan of your partial dentures.  You can remove them before bed and put them back in the morning. Just make sure to store your artificial teeth in a safe place, like a denture cup, to avoid breakage. Remember to clean them thoroughly before putting them back in your mouth.