Research Aim: This research will review the effect of praziquantel treatment on fish found to be infected with the platyhelminth parasite. The study will use captive fish since they are more susceptible to showing the parasite results than wild fish. This paper will also discuss the effect of this parasite if a human ingests an infected fish. The efficiency of the praziquantel and its toxicity information, assessments of administration routes, and pharmacokinetics are also reviewed.