The main differences between the Acer VG240YB and Acer QG241Y monitors lie in their product lines, design aesthetics, and specific features. While both monitors typically offer a 23.8-inch screen size and Full HD (1920 x 1080) resolution, they may have variations in design, bezel size, and stand features. The VG240YB may be part of Acer's VG series, and the QG241Y may be part of Acer's QG series, which might offer different connectivity options, gaming-centric features, or integrated technologies.