Eating sugar in excess can sometimes cause headaches for some people. Most of the time, sugar triggers migraines, a kind of recurrent, one-sided throbbing headache. The majority who experience headaches through increased intake of sugars are those who have underlying migraines and are unaware of them (8, 9). Another possible mechanism is more sugars lead to post-meal hypoglycemia due to complex mechanisms in diabetics related to its medications, ultimately causing headaches secondary to hypoglycemia (11).