Stands for Smart Access Memory and work with the AMD 5000 series CPUs and AMD 6000 GPU's. In short, it is a new way for your PC to access the whole memory capacity(VRAM) of an AMD 6000 series GPU. Previously this was done with 256MB paging of the VRAM called BAR(Base Adress Register). Depending on your motherboard brand it can be found in the PCIe section of the advanced menu or advanced settings and turn on Above 4G Encoding and Re-Size BAR Support.