There are some potential drawbacks and risks associated with using DIY laundry products. One concern is the handling of ingredients like borax, which should be done with caution to avoid inhalation or ingestion. Another risk is related to skin sensitivity since homemade detergents may not be as gentle on delicate skin compared to specialized hypoallergenic commercial options. Additionally, there might be variations in performance based on water hardness levels and fabric types when using DIY detergents.