The vast majority of patients with sarcoma are not at any increased risk of other cancers. A very small subset of patients has hereditary genetic defects that place them at increased risk for sarcoma and other cancers. For example, the tumor suppressor gene Rb is lost or not functioning in patients with retinoblastoma. These patients are often at greater risk of developing other types of tumors, including osteosarcoma.
We have genetic counselors available to assist patients in determining if they are at risk for other cancers. In most cases, your treating physician will not deem this necessary.