The gut microbiome is under constant assault from the modern industrial lifestyle: food, water, drugs all impact microbiome health. Maintaining and healthy diet, limiting medications and other gut damaging toxins will improve your odds of maintaing a healthy gut and skipping the probiotics. Some people find they feel better and don't need the same support as others. Others report to us that they cannot live without our products and know they will take them long term because they feel so much better when they do take them.