To run an eCommerce website, you need a combination of essential components. These include a domain name that represents your brand, web hosting services to ensure your website is accessible, and an eCommerce platform that provides product management and payment processing tools. You'll also need an inventory management system, a process for order fulfillment, and customer support channels to provide assistance. After building the website, you should optimize your website for search engines, and monitor analytics for creating strategies to attract customers.