Some of the immediate concerns for amputees are: Phantom pain. Many amputees suffer from phantom limb pain. Doctors at The Ohio State University Wexner Medical Center and College of Medicine have pioneered the use of primary targeted muscle reinnervation (TMR) for pain prevention, a procedure that “reroutes the nerves cut during amputation into motor nerves in nearby muscle.” Preparation of the limb for a prosthesis. For most patients, the treatment process includes surgery, a healing period, and a customized rehabilitation plan. The ability to use a prosthesis depends on the surgery, preparing the stump for a prosthesis, the use of a compression device, fitting for your limb for the prosthesis, learning to use the prosthetic device, maintenance of the prosthesis, and replacement of the prosthesis if the prosthesis wears out or there is better technology. Psychological harm. Most patients need psychological help and other types of support, such as joining amputee groups to begin to emotionally adjust to the loss of a limb. Other complications include infections, severe pain, and the risk of falling.