Bioactive peptides in Kambo are short chains of amino acids found within the secretion of the Amazonian giant monkey frog, Phyllomedusa bicolor. These peptides are considered bioactive because they have specific biological activities and can interact with the human body in various ways. While the exact composition of Kambo peptides can vary, one of the most well-known peptides in Kambo is Phyllomedusin.
These bioactive peptides in Kambo are believed to be responsible for the physiological and psychological effects experienced during a Kambo ceremony. They can stimulate the digestive and immune systems, potentially act as natural painkillers, and induce various responses such as nausea, vomiting, sweating, and increased heart rate and blood pressure.