If your toothbrush has a soft bristle, then you can use it for cleaning the turntable stylus by brushing it from front to back of the stylus. It would be best if you had oftenly cleaned your turntable stylus, which will really impact the sound quality of vinyl records. But we will recommend you to purchase an Ortofon Stylus fiber brush for needle cleaning instead of using a normal toothbrush which is specially made for cleansing the stylus tip properly.