Applicants must have successfully completed their 12th-grade examination from a recognized board or university, with Physics, Chemistry, and Biology (PCB) as compulsory subjects. They should have achieved a minimum aggregate score of 45%, with a relaxation of 5% for candidates belonging to the SC/ST category. Additionally, candidates must obtain a satisfactory score in the entrance examination conducted by RUHS. It is also essential for candidates to have obtained at least 45% marks in their 12th-grade examination, with a minimum of 40% marks for SC/ST candidates in the PCB stream.