To start your new hygiene regimen, make a yoga mat cleaner. Please check if there are any restrictions with your particular mat. For example, some mats say you cannot use a vinegar solution on them. Otherwise, here is what you need to make DIY cleaner:
Empty spray bottle
Water
White vinegar
Tea tree oil
Soft cloth
You can also use premixed mat cleaner. The vinegar and tea tree oil have antimicrobial and odor-fighting properties.