Yes, it is possible to ovulate while taking Hormone Replacement Therapy (HRT). This may be due to the fact that most hormone therapies used to treat menopause symptoms provide a combination of both estrogen and progesterone. These two hormones work together in the body, so when they are balanced correctly, it's possible for ovulation to occur. However, many women who take HRT find that their periods become more irregular or stop altogether; this could mean that you don't always ovulate on a regular basis. Additionally, if your doctor has prescribed a higher dose of one hormone over another – for example more estrogen than progesterone – then you could also experience fewer episodes of ovulation than normal. It's important to talk with your healthcare provider about how best to manage your symptoms and ensure optimal hormone balance while undergoing HRT.