Yes. A responsible pest control company will train its technicians to apply products as instructed on the label. Some products are safe to use directly on mattresses, others are not. Regardless, make sure you have a clean set of bed linens ready for use after the treatment.
At GOTBUGSIKILL, we encourage our customers to sleep on their beds from day one. Bed bugs are more motivated to come out from hiding when they can detect a host. While looking for a blood meal, the few bed bugs left over after the initial treatment will die as they cross over the various products we applied.