Although there are times when you do have to remove your aligners, including when you eat or clean your teeth, it's important that you wear them for most of the day.  Taking your aligners off for more than just practical necessities could cause you to quickly reduce the hours you need to wear them each day. And, simply put, Invisalign aligners won't work unless you wear them. Invisalign recommends keeping your aligners in for 20 to 22 hours a day, but we typically recommend at least 22 hours a day. Speak to your orthodontist for specific directions for your unique treatment.