The testing site that performs the COVID-19 test is responsible for reporting to the appropriate state or local public health department. Please note that state licensure requirements, as well as accrediting organizations’ standards for reporting SARS-CoV-2 test results, might be more stringent than CLIA and require dual reporting. These more stringent requirements must be followed. Exceptions for the performing reporting requirements might include a hospital system that centralizes data, i.e., a reference lab that has no connection to the patient’s state but sends the data real time to the facility that referred the specimen that does have that connection, etc.