If you use retinol regularly and experience no issues then there is no need to take a break. Consider it similar to a moisturizer. If you do experience problems with retinol then you can take a break from it and try an alternative product. Taking long breaks from retinol may cause your skin to build up more sensitivity to the product so if you do decide to go back to it then make sure you start with a lower strength and slowly get your skin used to it again.