The amount of runout in a drill press can vary greatly, depending on the quality and age of the drill press.
Ideally, you should have very little to no runout when setting up a new or recently serviced drill press; most professional-grade drill presses have less than 0.005″ of odd-to-even axis runout.
On the other hand, some older models may have as much as 0.010″ or more in their design. To ensure a perfectly accurate cut, always ensure your drill press has no noticeable play before starting a project.