Django stands out as an open-source web framework built in Python, and its extended use could be identified in the ORM, Migration, and MVC Monolitich Programming. Furthermore, Django is famous for providing support to database servers, scheduling, permissions, configurations, and roles. Once you gain command over Python and master it, you can get a grip of Django. On the other hand, Spring Boot is used for web development frameworks based out of Java. It is often called an opinionated framework since it assumes what the user needs beforehand. Compared to Spring Framework, Spring Boot is a convenient choice to make. Many other factors could be listed out, but it eventually depends on what works best for you.