Absolutely! The thickness of your latex mattress does matter. This is because the thickness of a latex mattress will determine the overall comfort, support, and durability. A thicker mattress will provide additional cushioning and can be more supportive than one that is thinner. A thicker mattress usually contains more layers which in turn offers improved breathability, temperature regulation, and motion isolation. With all this being said, you also need to make sure that the mattress fits within the weight capacity specified by your bed frame or foundation for maximum comfort and support.