Most of them can be efficiently dealt with if you have a good crowd control character like Venti, Sucrose, or Kazuha. Alternatively, you can also use hydro and cryo characters to freeze the enemies. This will give you breathing room for performing team rotation and deal a nice amount of damage. reasure hoarders aren't formidable enemies to deal with in the spiral abyss; however, when you face potioneers, you may run into unexpected elemental reactions that may hamper your team rotation or even damage you in the process. Most treasure hoarders' abilities aren't damage-oriented rather annoy players in their combat. So, my advice is to clear out ranged treasure hoarders as soon as possible and then focus on other enemies. Crowd control characters will do the job flawlessly when dealing with multiple enemies.