Although LDL cholesterol is still the major target for therapy, it is likely that in future, other lipid/lipoprotein and nonlipid parameters will also become targets for specific therapeutic interventions. Other significant lipid/lipoprotein parameters that have been associated with CHD include elevated triglyceride, oxidised LDL cholesterol and Lp(a) levels, elevated C-Reactive Protein, elevated homocysteine, and low HDL levels.