Ve filmu Power Rangers: Strážci vesmíru hrají Dacre Montgomery (Jason Lee Scott / The Red Ranger), RJ Cyler (Billy Cranston / The Blue Ranger), Ludi Lin (Zack Taylor / The Black Ranger), Naomi Scott (Kimberly Hart / The Pink Ranger), Becky G (Trini / The Yellow Ranger), Bryan Cranston (Zordon), Bill Hader (Alpha 5 (voice)), Elizabeth Banks (Rita Repulsa / The Green Ranger), Fred Tatasciore (Goldar / Putties (voice)), David Denman (Sam Scott / Jason's Father), Caroline Cave (Beverly Scott / Jason's Mother), Kayden Magnuson (Pearl Scott / Jason's Sister), Lisa Berry (Candace Cranston / Billy's Mother), Fiona Fu (Mrs Taylor / Zack's Mother), Robert Moloney (Ted Hart / Kimberly's Father), Anjali Jay (Maddy Hart / Kimberly's Mother), Patrick Sabongui (Mr Kwan / Trini's Father), Erica Cerra (Mrs Kwan / Trini's Mother), Wesley MacInnes (Colt Wallace / Bully), Sarah Grey (Amanda Clark), Emily Maddison (Rebecca / Young Lover #1), Drew Ray Tanner (Drew Tanner / Young Lover #2), Matt Shively (Damo), Morgan Taylor Campbell (Harper), Kenneth Tynan (Freak), Amitai Marmorstein (Geek), Tristan Rehwald (Ty), Donald Adams (Homeless Man), Clayton James (Young Cop), Garry Chalk (Captain Bowen), Fiona Vroom (Fenix Saleswoman), Sophie Lui (Television Anchor), Phillip Reed (Heavy Equipment Operator), Amy Jo Johnson (Cameo Role #1), Jason David Frank (Cameo Role #2), Jaime M. Callica (Officer Bebe (uncredited)), Kirk Kelly (Officer (uncredited)), Ranjit Samra (Security Guard (uncredited)), Peter Brown (Hipster (uncredited)), Tanis Dolman (Pedestrian (uncredited)), Lachlan MacDonald (Student (uncredited)).