DOCSIS 4.0 operates at frequencies up to 1.8 GHz. Most coax can operate at these speeds, but RG-6 coax (typical home coax thickness) loses power at 8.97 dB /100 ft at 1.8 GHz frequencies, so you'd either need to not run the coax very far, or use an amplifier, which would also increase noise. Splitters and other components may need to be upgraded to support these frequency ranges.