No, fever isn’t an expected side effect of Neulasta.
But fever can be a symptom of other side effects of Neulasta. This includes some serious side effects, such as:
acute respiratory distress syndrome (ARDS),* which is a severe lung condition
aortitis, which is inflammation in your aorta (the main heart artery)
leukocytosis, which is an increased level of a type of white blood cell called leukocytes
* For more information about ARDS, see the “Side effects explained” section below.
Fever can also be a sign that you have an infection. So you should tell your doctor right away if you get a fever during Neulasta treatment. They can help determine the cause and the best way to treat it.