Oftentimes, depending on your doctor’s availability, your insurance coverage, and your own personal preference, either option may work for you.  “Shots are somewhat better than drops for treatment of allergic rhinitis and asthma, with laboratory tests more likely to show favorable immune changes compared to drops,” says Howard Boltansky, MD, an allergy expert at Johns Hopkins Medicine.  He said those that are fearful of the treatments’ potential side effects may prefer shots, as they are administered by a healthcare professional. “Allergy shots must be given in a doctor’s office under observation so that possible adverse reactions can be treated,” says Boltanksy. “Allergy shots are the right choice for many people, but for others, sublingual immunotherapy offers more comfort and convenience, as well as greater flexibility to travel without the need to return to the clinic for shots.”