The odds can vary depending on two things – the type of roulette you are playing and the bet type being placed. If we look at American roulette, the odds of a straight-up bet (betting on a specific number) are 37 to 1. Betting on zero or double zero is 18 to 1, and then the odds begin to reduce as the bets become more specific. So the highest payout in American roulette is 37 to 1 (straight up), and the lowest is 1+⁄18 to 1 (numbers 19 to 36).