Hand sanitizer can be used to clean a toilet seat, but it may not be the most effective method. Hand sanitizers are primarily designed for cleaning hands and killing germs on the skin. While they can be used on hard surfaces like toilet seats, they may not be as effective as dedicated toilet seat sanitizers. Toilet seat sanitizers are specifically formulated to kill tough germs on toilet seats, providing a higher level of disinfection. Therefore, it is recommended to use toilet seat sanitizers for the best results in terms of hygiene and germ-killing power.