No. You can’t recover your Enpass account if you lose either your master password or your Keyfile — which is used as a second factor of verification, although it’s not as secure or intuitive as regular two-factor authentication (2FA).
If you lose your master password or your Keyfile, you need to reset your Enpass account, and then all of your data will be lost.
If you’re looking for a password manager with multiple recovery options, LastPass is a good choice.