In general, anyone with an allergy to acai should not eat it. Additionally, those who are pregnant or breastfeeding should consult a doctor before eating acai as there is limited research on its safety during these times. Acai also contains naturally occurring plant compounds called oxalates which can be difficult for some people to digest and could lead to kidney stones if consumed in excess. Lastly, individuals with existing gastrointestinal issues such as irritable bowel syndrome (IBS) may want to avoid consuming acai due to the high fiber content that could further exacerbate symptoms.