In short, no. Even pushed at the fastest speeds possible, a .177 caliber pellet lacks the energy needed to ethically take a coyote. I’ve heard of coyotes killed with .25 caliber air guns, but even those are probably still a little on the light side. If you were serious about hunting coyotes with an air rifle, look at .30 caliber models that can produce 100 foot-pounds of energy or more.