Granulation is a core step for the production of OSD (oral solid dosage) products, mostly tablets and capsules. Granules can be applied directly in sachets, be compressed to tablets, or filled into capsules.
The process step of granulation leads to: Improved flowability Narrow particle size distribution Homogeneous distribution of API and excipients Reduction of segregation Increased bulk density Improved compactability Reduction of incoming material variation