Inhibition of Hepatic Drug Metabolism - According to a research paper on the NCBI website, one such side effect is the inhibition of hepatic drug metabolism, and the decreased activity of glycoprotein. Cannabinoids can influence some pharmaceutical drugs through the process of inhibiting liver enzymes called cytochrome p450. It’s important to consult with your doctor before adding CBD to your daily regimen. Dry Mouth - Some people can potentially get a dry mouth, which is thought to be because the endocannabinoid system may restrict saliva secretion. Decreased Blood Pressure and Lightheadedness- It has been reported high doses of CBD can result in a decrease in blood pressure. This effect on blood pressure can be seen in just a few minutes of taking CBD. If you’re on prescription medications for your blood pressure, you should consult with your doctor before taking CBD. Low blood pressure can cause you to feel lightheaded. If you experience this, drinking a cup of tea or coffee may help.