Psoriasis and eczema both result in inflamed, itchy skin, but they have distinct differences. Psoriasis typically manifests as thick, silvery scales and plaques. Eczema, on the other hand, often presents as red, inflamed patches that may ooze or become filled with fluid. The affected areas for eczema can also be more widespread. Additionally, the triggers and underlying causes for each condition can differ, with psoriasis often linked to immune system responses and genetics.