Your Glowtox injector will apply a topical anesthetic to numb the area before injection. Next, the treatment area will be cleansed, and your injector will inject the filler into the area with a needle or cannula. During Filler injections, some needle pricks can be felt, and there may be some mild discomfort. The pain dissipates quickly, but you can expect possible swelling, bruising, and tenderness at the injection site for 24-36 hours.