The best way to get rid of wrinkles in your comforter is to fluff it. Start by shaking the comforter vigorously to help the filling become evenly distributed. Hang the comforter outdoors and let the wind help the filling fluff up. If you don't have access to outdoor space, use a hairdryer on a low setting to soften the fabric. You could also lay your comforter on a flat surface and use a rolling pin to flatten out the wrinkles.