The Fluorescent Yellow is compatible with both inkjet and laser printer technologies. Copy machines are the same technology as smaller desktop laser printers, however they do tend to run much hotter. Because of this we recommend testing with a Plain or Unspecified material setting first. If the toner rubs or flakes off, you can adjust to a heavier setting like Labels or Cardstock. You are welcome to visit the link below to try samples of this product. We will be happy to send you a few sheets at no cost for testing on your machine. https://www.onlinelabels.com/samples