In general, it makes no difference when time of day you take a urine sample, but there are certain exceptions. For example, your doctor may request an early morning urine sample since the urine is more concentrated and hence more likely to reveal any abnormalities. On the other hand, testing mid-day urine will allow for better comparison with results from a previous visit or study. Urine tests are used to check for problems such as diabetes, kidney disease, and urinary tract infections (UTIs). While any type of urine test can detect these conditions, some tests are more effective than others at specific stages in their progression. For example, if you have recently been diagnosed with diabetes but your blood sugar levels have already returned to normal, then a single mid-day urine test won't be able to tell this. However, if your blood sugar remains high over several days or weeks, then this would show up as abnormal results on a mid-day urine test. Mid-day means between 10 a.m. and 2 p.m., so if you cannot wait until then, then choose a time when you can provide a reliable sample. The staff at the laboratory will be able to advise you on what time range should be suitable for different tests. Some common options include first thing in the morning before going to work or school, around lunchtime, after dinner, night time - even while you're sleeping!