The nucleolus and ribosomes are closely related, with the nucleolus being responsible for the production and assembly of ribosomes. Ribosomes are composed of ribosomal RNA (rRNA) and ribosomal proteins, which are produced and assembled within the nucleolus. Once assembled, ribosomes are exported from the nucleolus and migrate to the cytoplasm, where they engage in protein synthesis. The relationship between the nucleolus and ribosomes is thus one of production and assembly, with the nucleolus providing the necessary components for the formation of functional ribosomes.