During the 2021 NCAA Division I baseball season, the Kansas State Wildcats represent Kansas State University. As a member of the Big 12 Conference, the Wildcats play their home games at Tointon Family Stadium. The team is led by head coach John Cohen, who has been with the program since 2015 after spending four seasons as an assistant under Clint Hurdle at the University of Florida. They are the only team in the country to win 100 games during the regular season and claim a No. 1 seed in the NCAA Tournament. K-State reached its centuryth victory on May 30, when they defeated Oklahoma City 2-1 at Tointon Family Stadium. The game was played in front of a crowd of 9,823, the third largest attendance for a one-game postseason event behind only the College World Series and MLB's National League Championship Series. K-State finished the year with a record of 100-28-1. They were ranked No. 1 in both the Baseball America and USA Today Coaches' Polls at the end of the season. This is their first trip to the NCAA Tournament since 2008. They lost to Florida State 3-0 in the Super Regionals. The Wildcats have made 11 appearances in the NCAA Tournament, most recently in 2016 when they fell to Miami (FL) in the Super Regional round.