It is rare, but Juvéderm can cause some side effects at the injection site, such as swelling, tenderness, bumps, firmness, pain, bruising, discoloration, redness, and itching. These reactions are usually minor and short-lived, usually disappearing within a week. However, if the swelling or redness persists for more than a few days or weeks, it’s important to call our medical team. Please review important safety information regarding Juvederm.