The best thing to do is spot clean when smaller spots show up. I usually use Shout Wipes for that, but Jana has used tide pens in the past. Make sure if there is a white top print to be a little more gentle on rubbing spots out. Since the ink sits on top of the fabric a bit more than other colors, there is a chance of the ink rubbing off and getting on other parts of the fabric.  But, you can put your Jana Lam's in the wash. I usually use a hand wash cycle and lay flat to dry. After it's dried, it is always good to give it a little bit of an iron. We use 100% cotton fabric, so it may shrink in the dryer, but will definitely stand up to ironing.