The drops are usually given when the infant experiences the problems of gas, as they work quickly in minutes to help them. Once you know that your child has a constant issue with gas after they eat, then it may be beneficial to give the drops first before they eat or feed. This is a personal call on the parent’s part as to when is the best time for the medicine. You will have to see when it does the most help for the infant, either before, during, or after the meal.