Burn cream is used to help heal and protect a burn wound. It also creates an antimicrobial barrier that will protect the wound from infection. Enriched with vitamins A, D, E, and aloe vera, burn cream can provide immediate relief and can also help prevent infection of the burn. As a burn heals, it can become very dry and may crack. If the skin cracks, it opens up the wound to infection. A burn cream will keep the burn moisturized so it will avoid cracking and further irritation.