The appropriate age for starting Bio-identical hormone replacement therapy (BHRT) can vary depending on individual circumstances and the specific type of BHRT. Generally, women may begin considering BHRT around the time of menopause, typically between the ages of 45 and 55, to manage symptoms like hot flashes, night sweats, and mood changes. However, BHRT can also be prescribed for younger women experiencing premature menopause or other hormonal imbalances. It’s important to consult with a physician to determine the best timing and suitability for BHRT based on your health and medical history.