When it comes to playing Rocksmith, there aren't any specific features or specifications that make a guitar suitable for the game. Any electric guitar can be used with the game as long as it has a standard 1/4-inch output jack that can be plugged into the Real Tone cable included with the game. However, certain features may make a guitar more comfortable or enjoyable to play, such as a slim neck profile, lower action, and lighter weight. Additionally, guitars with single-coil pickups may be more prone to producing noise or interference with the game, so guitars with humbucker pickups or coil-splitting capabilities may be preferred. Ultimately, the best guitar for Rocksmith will depend on the individual's playing level, style, and personal preferences.