A latex allergy is most often caused by the sap proteins in rubber trees. The most common latex allergy is from skin contact with gloves or other latex products. Since our plant-based latex is wrapped in wool, cotton, and then fabric, there won't be any direct skin contact. Some people have an allergic reaction to natural latex by breathing in latex particles, but this is very rare. If you are allergic to latex through a skin allergy, you should be safe to order this product, but you may order a latex sample to test. If you have a respiratory latex allergy, we recommend you opt for the CertiPUR-US-Certified poly foam option.