There is actually a study that was published on PubMed and it addresses this very issue right here. The effect that a high daily intake of this fatty acid would have on your liver and kidney function was studied and 20 subjects were received. Each of the subjects received strong doses of different types of CLA a day for three straight weeks. The study came to the conclusion that this amount of intake would not produce “clinically relevant” effects on either your liver or kidney functions. Then again, it is also worth noting that all the subjects tested were healthy and did not have persisting kidney or liver issues.