In most of the freezer packs, the gel is not toxic. It is also biodegradable as it is made of polymer and cellulose. If this gel comes in contact with the skin, it may not cause any issue or irritation. Moreover, the chances of getting poisoned by this gel are meagre, and one needs to consume a large quantity to experience any health issues. However, in some cases, it can cause a little irritation if it comes in contact with the eyes.