Feeling better depends on the person, the hormones needed, the hormones taken, and so many other factors.  We have had patients that have started care that felt better within days and we’ve had patients that it took 5-6 months.  For some the change is so gradual they didn’t realize they felt better until they stopped therapy. In turn, patients got back on treatments as soon as they noticed how bad they felt before starting care.   Understand that hormone depletion doesn’t happen overnight and it can take time to get everything balanced back out and where it needs to be to feel the full effects of optimum hormone levels.