Experts indicate that genetics contributes 75% to the development of celiac disease and the remaining 25% to environmental factors. Therefore, it is important to know the genetic predisposition to celiac disease. In both children and adults, it will allow planning a closer follow-up to detect the disease early, to rule out cases of subclinical celiac disease and latent celiac disease, where they exist. This is important, as late diagnosis and lack of appropriate measures often leads to other autoimmune disorders, such as dermatitis herpetiformis, type 1 diabetes or rheumatoid arthritis.