Toothpaste is known to be an effective method for removing stains from a variety of surfaces, but it does not work on blood stains. While toothpaste has some bleaching properties, it's not strong enough to completely remove a completely dried in blood stain. To ensure the most effective and safe blood stain removal, it is best to consult with a professional dry cleaner or check out online tips that use common household items like hydrogen peroxide or detergent.