During each procedure, every patient will receive injections directly into the scalp. Most people feel some mild discomfort during and after their first treatment, as it is brand new to them.   Those prone to headaches should try to get a good amount of rest after the first treatment. It’s perfectly fine to take over-the-counter pain medication to help with the discomfort if it lingers into the night or the next morning.   Other than that, there are no side effects connected to PRP treatments. With more scheduled treatments, the majority of people can return to their normal schedules without any downtime.