MSM has been found in studies to provide anti-aging and skin-health effects. A clinical experiment on MSM demonstrated the anti-aging advantages of oral supplementation. According to the study, 100% of subjects who took MSM had a reduction in the amount of wrinkles, with an average reduction of 38%. The same study showed that topical application of MSM can be as effective as taking it orally. Further research is needed on the long-term effects of MSM on the skin, possible side effects from using it orally or topically, and how well it works for people with different skin types. But this ancient medicine may help reduce the appearance of wrinkles and improve the look of aging skin. Take care of your skin, just like you would any other part of your body. It is important to eat well and stay active, sleep enough, and use sunscreen if you want to have healthy looking skin as you age.