The most famous lefty is probably Barack Obama. The lefty here doesn't refer to political affiliation, but a person who is left-handed.
Barack Obama is a pretty good example of a lefty. He was the US president from 2009 to 2017. Obama was also the 44th President of the United States.
There are some other famous lefties, such as Prince William, Steve Jobs, Mark Zuckerberg, Justin Bieber, and Angelina Jolie.