Yes, it is completely safe and will not degrade the quality of our Beta Glucan.
For an enzyme, or specifically a beta glucanase enzyme, to degrade the beta glucan molecule it would have to be capable of breaking down our specific 1,3 1,6 linkage. For instance, the most common beta glucan molecules available in everyday foods like oats and barley are made of a 1,4 linkage.
In almost all cases none of these enzymes or beta glucanase enzymes will be able to break down our beta glucan. But for peace of mind and to be sure there is no breakdown of the molecule, just take your Beta Glucan 30 minutes before your enzymes just like you would any food, or unless directed otherwise by a healthcare professional.