Technically, yes you can, but LISAs are not designed to be used for general saving, and you’ll be penalised if you make a withdrawal that isn’t for one of the reasons listed below.
There are only three occasions when you can access your funds without paying the penalty:
When you buy your first property (up to £450,000)
When you reach 60
If you’re terminally ill, and have less than 12 months to live
If you take out your money at any other time, you’ll have to pay the Government a penalty worth 25% of what you are withdrawing. This allows the Government to recover the 25% bonus they have paid on your deposits, plus a little more to dissuade you!
So, unless it’s a genuine emergency, it’s not normally a good idea to withdraw your money until you reach one of the life stages that LISAs are designed for.