Both Acuvue Trueye and Moist incorporate advanced comfort features but go about how they achieve comfort slightly differently. Acuvue Trueye uses a system that consistently maintains a moist lens surface, that works with your natural tear film (Hydraclear). Acuvue Moist works to create a cushioning effect via a wetting agent that's built into the lens. In truth, both lenses are known to be very comfortable, a consultation with your ECP will help determine your specific needs.