Turmeric is often well-tolerated, and in fact, is known for promoting healthy digestion due to its anti-inflammatory and antioxidant properties. However, everyone's body is unique and responds differently to dietary supplements. While turmeric and piperine can support overall gut health and digestion, some people with sensitive stomachs might experience mild discomfort when first introducing these ingredients into their routine. This is because spices like turmeric and piperine can stimulate gastric acids. If you do have a sensitive stomach, it's recommended to start with a smaller dosage to see how your body reacts and gradually increase as your body becomes accustomed. You might also find it beneficial to take the supplement with food, as this can often help mitigate potential discomfort.