I suggest preheating your over to 450° F.  Right before you put the bird in, reduce the heat to 325° F.  From there you are going to bake the turkey 15 minutes per pound. The internal temperature of the bird needs to reach 165 degrees for safe consumption. To ensure you reach that temp and don't overbake - use the Chef Alarm.  You simply set your max temp and an alarm will sound with your turkey has reached that temperature.  ThermoWorks really makes your Thanksgiving Turkey come out perfect. I promise you'll be left with a moist flavorful turkey at your Thanksgiving table.