Yes, certain cat breeds show a higher predisposition to feline hyperesthesia syndrome. Breeds such as Abyssinians, Burmese, Persians, and Siamese are particularly prone to this condition. This vulnerability may be due to genetic factors or specific breed characteristics. However, it's essential for all cat owners, regardless of breed, to be aware of the symptoms and seek veterinary advice if they notice signs of the syndrome in their pets to ensure proper management and care.