I said before that Pico de Gallo is also often called salsa fresco, which translates to "fresh sauce." But they are actually two totally different things. The biggest difference between salsa and Pico de Gallo is that salsa contains more liquid. It's made with roasted tomatoes, which are then crushed into a chunky texture. Pico de Gallo tomatoes aren't cooked and therefore hold their liquid. The end result is a much drier, more textured dish.