The ingredients in Migraine Stick are generally considered safe during pregnancy. However, some people think it is best to not use essential oils at all during the first trimester. We suggest speaking with your doctor first before using Migraine Stick or Cream, especially in your first trimester or if you have complications with your pregnancy, just to be safe. In breastfeeding women, there is some evidence that peppermint can reduce milk flow. This is most likely to happen when consuming large amounts of peppermint, such as drinking peppermint tea or eating peppermint candy. We have not seen evidence of this happen when applying products containing peppermint oil topically, but it is something to be aware of. Here are a few good articles on this subject: The BumpGood Housekeeping