Yes, Low Dose Naltrexone (LDN) can be used for weight loss, although it is not its primary FDA-approved use. LDN was originally approved for treating opioid and alcohol addiction, but its off-label use for weight loss has gained attention. The mechanism behind LDN's effectiveness in weight loss is believed to be related to its impact on the body's endorphin levels and its role in regulating appetite and inflammation. By influencing the brain's reward system, LDN may reduce food cravings and help control emotional eating. However, it's important to note that LDN should be considered as part of a comprehensive weight loss plan, which includes diet, exercise, and lifestyle changes. Consulting with a healthcare professional is crucial before starting LDN for weight loss to ensure it's appropriate for your individual health needs and to discuss potential risks and benefits.