The downtime will vary between individuals. Most people will find that the peeling and redness lasts around 5-7 days. Those people who have a stronger reaction may find their downtime lasts a little bit longer. Dermamelan is a very safe procedure delivering excellent results. However, some common side effects can occur: Tightness: 5-6 days after your Dermamelan cream mask is removed, your skin can feel tight and may appear swollen. Skin Peeling: it is normal to experience some level of peeling of your skin within the first 7 to 21 days. This can vary from patient to patient, and you may want to consider booking a few days off from work. The peeling can persist during your treatment course, but this usually starts to settle as the skin begins to build up a tolerance.