While there’s no guaranteed way to prevent someone from developing bipolar disorder, many people successfully manage it with the right treatment and support. A successful strategy may include medication, therapy and other self-help strategies. If you have a family history of bipolar disorder, it’s important to be aware of early warning signs, and for friends and family to be aware of them too. Avoid taking substances that can trigger manic or hypomanic episodes such as: recreational drugs such as cocaine, ecstasy and amphetamines excessive amounts of caffeine Other ways to prevent relapses or episodes include learning to manage your stress and getting enough sleep.