Typical probiotics on the market often contain lactobacillus and bifidobacterium. When a dog has SIBO, those probiotics can propagate in the small intestine, exacerbating the problem. Instead, the probiotics in Soil & Sea remain intact until they reach the lower intestine and colon. Additionally, Soil & Sea does not contain sugars from typical prebiotics like maltodextrin, which makes SIBO worse.