Both are excellent treatments in the right candidate, so ultimately, the right option for you depends on your concerns and treatment goals. Nucleofill works on skin quality and is used for patients concerned with fine lines and wrinkles and loss of elasticity on the face or neck. It treats various concerns and is an excellent option for under-eye crepiness, puffiness, wrinkles, and hollows. Fillers, on the other hand, are more suitable for those with significant volume loss, imbalances or those who wish to restore definition. They are used to augment a specific area via a lifting and volumising effect. While they can give the skin greater luminosity, Nucelofill takes a more holistic approach for widespread improvement of the skin whilst stimulating collagen production and smoothing lines and wrinkles.