According to the National Institutes of Health (NIH), acetaminophen has many of the same uses as NSAID pain relievers, but it’s not an anti-inflammatory drug. That means it isn’t as effective as ibuprofen at reducing swelling or inflammation, such as from a sprained joint or a muscle ache. However, acetaminophen does help reduce fevers, and, like NSAIDs, also relieves minor aches and pains. As with NSAIDs, a doctor can prescribe acetaminophen at a higher strength to treat chronic arthritis or other serious pain. You shouldn’t take acetaminophen if you:
Have severe liver or kidney disease.
Are already taking a medicine containing acetaminophen.
Have more than three alcoholic drinks per day.