When you buy CBD from a reputable, trustworthy brand, like Comfort Zone, you can trust that you're getting a high-quality product. However, as with any dietary supplement, there is always the risk of an adverse reaction and/or interaction with medication. Consult with your physician before you begin taking CBD in order to ensure it's the right fit for you. While CBD is considered a safe compound, even at high doses, it may produce some uncomfortable side effects including, nausea, lethargy, stomach aches, and dry mouth. However, these adverse effects are temporary and should subside within 4–6 hours.