ProfitSource is designed to operate on a Microsoft Windows OS and may not run natively on a Macintosh OS. However the good news is that there are a number of robust solutions available that allow you to run Microsoft Software on Apple Mac Desktops and Laptops. You can use one of these solutions to run ProfitSource on a Mac. Depending on the model and year of your Apple computer you may be able to leverage the free BootCamp application from Apple that is pre-installed on your Apple computer to run Windows from a dual-boot partition. Otherwise a solution like Parallels Desktop may work for you.