If you are used to solo running, there will most likely be an adjustment period for becoming used to pushing a stroller during your run. Some factors that affect the difference include your child’s weight, any baby gear you stow in the stroller for the trip, and of course the surface and environment you are running in and on.
For most, it becomes natural after a while, although you probably won’t be keeping up with the same speeds you were keeping when you were going solo. One thing to think about is the fact that it can become a way to also increase your strength. After you get used to pushing a stroller, eventually picking up your speed, once you go on a solo run, you may find that you feel much lighter and are able to go a bit longer and faster.