Yes it will fit the 2006 Lexus GX470. However the G/293-83-150T was designed for the older Toyota 4X4 pickups and these wheel spacers are 1.5 inches wide and have a large center bore to work with locking hubs. The G/293-83-125T is the most correct application. I do recommend purchasing GOR680338, 12 each of these with the pair spacers. This is a 12mmx1.5 thread, open end ET style lug nut. This would be used to bolt the wheel spacer to the vehicle and because of the extra treads that it has it would be a better choice than the open end lug nuts that come in the kit.