Yes, tolcapone increases dopamine levels in the brain. By inhibiting the enzyme COMT, tolcapone prevents the breakdown of dopamine, leading to increased levels of dopamine in the brain. This increase in dopamine helps alleviate the motor symptoms associated with Parkinson's disease. However, it is important to note that tolcapone is typically used in combination with other medications that also affect dopamine levels in the brain for more comprehensive management of Parkinson's disease symptoms.