For best results, take the two supplements together, as follows: 1 capsule of Biosnel Formula Potenziata + 1 capsule of Diuresan Formula Potenziata mid-morning away from main meals, and then 1 capsule of Biosnel Formula Potenziata + 1 capsule of Diuresan Formula Potenziata mid-afternoon, always on an empty stomach, or at least one hour before or after your main meals.