Although dermal fillers and BOTOX Cosmetic are both injectable treatments that are used to reduce the appearance of wrinkles, they work in very different ways. As their name implies, injectable fillers use an ingredient to physically fill in wrinkles from below the skin’s surface, effectively reducing their appearance. BOTOX and Dysport both use a purified form of the botulinum toxin to temporarily relax the muscles that cause “dynamic” wrinkles (the wrinkles that occur when we make facial expressions), such as crow’s feet, to form. When used strategically, BOTOX and dermal fillers can both create beautiful outcomes.