Yes, it is possible to use retinol serum on sensitive skin, but it is important to be careful and let your skin get used to it slowly. Start with a lower concentration and apply it only every few days to see how your skin responds. If you notice redness, dryness or irritation, reduce the frequency of application or switch to a milder product. It is also advisable to use the serum only in the evening and wear a sunscreen during the day, as retinol can make the skin more sensitive to UV rays.