Most of the time, you can expect about a full 24 hours to recuperate after a colonoscopy, and a number of patients are well enough to start their daily routine the following day. If colon polyps are removed, recovery may last about a week. It is not uncommon to experience some GI irritation following a colonoscopy, such as cramping and bloating. Our San Antonio Gastroenterology Associates doctors will give you more information about what you can expect during your recovery.