There are a wide range of technologies that can help you to detect and protect against all types of malware attacks. Microsoft Defender for Endpoints and Defender for Microsoft 365 are the next level of anti-virus, so to speak, using Artificial Intelligence to pinpoint unusual behaviours within your systems. These can even be set up as Cloud Access Security Brokers in order to manage the cloud apps and services that your teams are using. There are also tools like Azure Active Directory which can help you to manage your users and privileges, ensuring that the access an attacker can gain through installing malware is significantly limited.