The key difference between CBD and THC is THC causes intoxicating euphoric effects that make you feel high. THC initiates the physiological response when it reaches the cannabinoid 1 receptors (CB1), found primarily in the brain and the central nervous system. Conversely, CBD doesn’t bind with CB1 receptors and actually inhibits CB1 agonists (in this case, THC). This means CBD will never get you high regardless of how much is consumed, and also acts to suppress the high caused by THC.