With cautious optimism – yes. Fertility treatments available today allow about 50% of those with the syndrome have children using the techniques of [micro-TESE]  and [ICSI]  . However, a significant percentage of men with the syndrome are defined as “mosaic”, meaning that some of their cells contain the extra X chromosome and others do not. In these men there is a chance of finding sperm cells by an [extended spermatozoa search] , and in very rare cases, there are men who have enough spermatozoa for [ICSI] just as is!