Yes, ductless AC systems do require regular maintenance to ensure optimal performance and longevity. Regular cleaning of the filters, usually every month, is essential to maintain airflow and efficiency. The coils and blowers should be inspected and cleaned annually by a professional to prevent buildup and ensure efficient operation. Additionally, checking the refrigerant levels, drainage system, and electrical connections is crucial. Regular maintenance not only improves efficiency but also helps prevent costly repairs and extends the lifespan of the system.