Like all medicines, Zidoval Gel can cause side effects – but not everyone will get them. The most common side effects include; headaches, cramps, nausea, unpleasant taste, dry skin, rash, irritation, vaginal discharge, and loss of appetite. Some women can also get a fungal infection called thrush after taking a course of antibiotics, especially when using a topical gel around the vagina. This happens when the antibiotics kill the normal bacteria in the vagina that help to protect you from fungal infections like thrush. [popover id=ref6]