While a substance use disorder for drugs like mescaline are much less likely, they do occur. The problem with mescaline is that a tolerance to the drug can rapidly develop.Although the drug isn’t associated with the development of physical dependence, some studies correlate specific risks with using the drug. For instance, there are some recorded cases of birth defects caused by mescaline use during pregnancy. It’s also possible to overdose on mescaline and suffer adverse physical effects from it.A small percentage of users develop a hallucinogen use disorder. These people often experience flashbacks and feel like they’re under the influence of the drug after months of abstinence.Therefore, if you’re trapped in a cycle of addiction, you must reach out to get help today to prevent these kinds of ramifications.