The right product really depends on the model you are trying to create. The ULA products are great if you are trying to create 3D structures that don’t require polarity like spheroids. Flat ULA products will create lots of spheroids but they will be of different shapes and sizes. If uniform spheroids are needed round bottom ULA plates like the Spheroid microplate are a good option. Microcavity ULA plates offer the best of both flat and round ULA products by forming multiple uniform spheroids per well. If polarity of the model is required like with Organoids than Matrigel or some other ECM will likely be required.