8 Best Supplements for Circulation Omega-7 Fatty Acids. Palmitoleic acid is a purified and concentrated form of one specific omega-7. ... Coenzyme Q10. (CoQ10) supports circulation by inhibiting the formation of blood clots. ... Fish Oil. ... L-arginine. ... Nattokinase. ... Niacin. ... Resveratrol. ... Systemic Enzymes. Apr 4, 2022