In a behavioral study to evaluate the use of Opill in an OTC-like environment, participants correctly used Opill or followed label directions to use a barrier method during intercourse for the 2 days following a missed pill without assistance from a healthcare provider on 97% of active-use study days.31 Additionally, 95% of study participants were ≥85% adherent to daily Opill dosing or followed label directions to use a barrier method during intercourse for the 2 days following a missed pill.31 The results of this study indicate that the Drug Facts Label guides people to use Opill correctly without involvement of a healthcare provider.