Treatment depends on the STD and may involve taking medicine by mouth or getting a shot. You may also be prescribed creams or suppositories. In some cases, we can begin treatment in the office during your visit. Some STIs can be cured while some cannot be cured, and we use medicines to manage their symptoms. Herpes, HIV/AIDS cannot be cured and are controlled with medications. If you test positive for an STD, your partner may need to be tested and or treated as well.