No, this can be used as a standalone system without connection to a PC, unless you have blended meetings in which some participants appear in person at the meeting room and some remotely through zoom for example. You do not need to connect it to separate mixer either as each mic has a built-in speaker, unless you’re using the system with a large audience in which case you can connect the control unit to a separate PA system with loudspeakers. In this plug and play system, microphones are daisy-chained to one another and the last microphone in the chain is connected to the control unit.