There are many ways to open Disk Cleanup and the common five ways are displayed below. Way 1: Type disk cleanup into the Windows search bar and then hit the Enter key. Way 2: Open File Explorer, then right-click a drive and choose the Properties option, and finally click the Disk Cleanup button. Way 3: Go to the path: Control Panel > System and Security > Administrative Tools > Disk Cleanup. Way 4: Open Command Prompt or Windows PowerShell, type the cleanmgr command, and hit the Enter key. Way 5: Press Windows + R to launch the Run dialog box, type cleanmgr, and click the OK button.