Breed standards are written to ensure the health of the dog breed and that the best breeding practices are followed. Therefore colors listed as standard won't affect the health of your dog. Others, however, might. Dogs that are specifically bred for color are likely to suffer from various health conditions. This is particularly true for Isabella, liver, and formentino Cane Corsos who are more susceptible to issues such as Color Dilution Alopecia. Dogs that are only bred for color can also suffer from many other skin diseases, deafness, eye deformities, and skin cancer.