Thermage uses radiofrequency energy while Ulthera uses ultrasound energy. Thermage treats more superficial lines and wrinkles on various parts of the face and body and is recommended as a preventive treatment. On the other hand, the corrective action of Ultherapy targets deeper layers of the skin on the face, neck, brow, and décolleté to lift and tighten the treated area. Both treatments are recommended as part of an annual skin rejuvenation maintenance program and can be combined or alternated for optimal results.