Possibly. A large design print might not fit onto a youth small shirt, fitted ladies shirt or tank, and conversely, the smaller print size required for a youth or ladies shirt might look too small for an adult XL shirt. Our design team will let you know any potential conflicts during the art approval process. The common solution is to print a smaller version of your design on the youth shirts. However, depending on the complexity of your design, there can be an additional cost involved. We will work with you to keep this to a minimum while getting your desired outcome.