Psychosis is a very serious mental condition. Major causes of psychosis include genetic factors- Research shows that schizophrenia and bipolar disorder may have a common genetic cause. The second factor is Hormones- Some people experience postpartum after giving birth. Due to this, some experts have suggested that hormonal factors may play a role in those with genetic susceptibility.  Psychosis can be disruptive, but treatment is available to help people manage it.