The very first Instagram post was posted on 5:26 PM on July 16, 2010 by Mike Krieger, one of the co-founders of Instagram. The first Instagram post was the picture of South Beach Harbor at Pier 38. The second Instagram post was posted on 9:24 PM on July 16, 2010 by Kevin Systrom. It was a photo of a dog and his girlfriend's, Nicole's foot.