The duration of facial fillers is dependent on the medium used to fill the wrinkle, fold, contour defect, or deflated lip and/or cheek. The most effective and safe fillers on the market currently are Radiesse and Restylane/Juvederm. The Radiesse product is made of coral material found on the ocean floor. The coral is modified to mimic bone-like substance. As such it lasts longer than traditional filler materials, and is excellent for the cheeks, between the eyebrows (glabella), chin, and laugh lines (nasolabial folds and marionette lines) which are overlying bony prominences.
Radiesse will last approximately one and a half years. Restylane and Juvederm are both a matrix that is made to mimic a naturally occurring protein that preserves space between cells acting much like a sponge or cushion. As such, Restylane and Juvederm are ideal for filling areas that are meant to be soft such as the lips. Restylane and Juvederm last approximately six months.