This product is very active and may exacerbate the bacterial condition often associated with blemishes. If you have only a few blemishes, simply avoid the affected area. If the condition is more severe and the skin is problematic overall, simply avoid using this serum until the condition clears up.This product is very active and may exacerbate the bacterial condition often associated with blemishes. If you have only a few blemishes, simply avoid the affected area. If the condition is more severe and the skin is problematic overall, simply avoid using this serum until the condition clears up.