The Exosome is a sophisticated molecular mechanism that is responsible for the destruction of specific kinds of RNA molecules. It does this by binding to the RNA molecules and cleaving them into smaller pieces. It does this by detecting and attaching to specific RNA molecules, including mRNA, and then disassembling those molecules into their parts. The Exosome accomplishes this objective via the coordinated efforts of many distinct enzymes, including endonucleases, exonucleases, and ribonuclease H. These enzymes cooperate to disassemble the RNA molecule that serves as the target into its component components. After separating these components, they may be recycled or subjected to additional destruction until they are transformed into new molecules.