Yes, you can put Gold Bond powder on your dog's hot spot. But you need to follow the guidelines given above to carefully use them on your dog.  Hot spots are generally open, similar to wounds on the skin. You can apply the Gold bond powder to your dog's hot spot. This skin irritation powder works equally on humans and pets.  This skin powder is great for treating mild issues of the skin such as yeast infections, wet feet pads, hot spots, and itchiness. But make sure that your pets, such as cats or dogs, are not ingesting this powder, as consuming it regularly can create issues for them.