Yes, active speakers can be connected directly to an amplifier. Active speakers have built-in amplifiers, so they don't require an external receiver. Simply connect the output of the amplifier to the input of the active speakers using speaker cables. This setup eliminates the need for a separate receiver and allows for a straightforward connection between the amplifier and the speakers. Active speakers are a convenient option for those who want to simplify their audio system setup without compromising on sound quality.