There are different types of nasal sprays. Saline nasal sprays do not have side effects, while steroid nasal sprays may thin the tissue of the nose with repeated or long-term use. Steroid and antihistamine nasal sprays may increase the risk for nosebleeds. Antihistamine nasal sprays may cause drowsiness, dizziness, or dry mouth. Decongestant nasal sprays may cause burning or stinging in the nose as well as increased heart rate or blood pressure. If used for several days in a row, decongestant nasal sprays may worsen congestion.