[dropcap_q]Q:[/dropcap_q] My puppy used to sleep through the night, but now is waking me up frequently. If your puppy suddenly needs to go out to pee a lot more often, they may have a bladder infection. This is very easy to check for and treat — your vet will look at a urine sample for signs of infection and, if necessary, your puppy will be put on a course of dog antibiotics.