Prednisone should be taken as a single dose once a day, just after breakfast. For example, if your daily dose is 30mg, you should take 6 pills (6 x 5mg) all at once after breakfast. If you miss a dose of prednisone, take it as soon as you remember. If it's within 12 hours, no problem. But if you miss a dose between 12 and 24 hours later, then use that missed dose as your first dose of the next day. So if you normally take 30mg doses, then you'd actually start the next day with 33mg! That's why it's important to keep track of what doses you take and when so that you don't miss any doses. Missing doses may cause poor treatment results and increased risk of side effects. Also, if you stop taking prednisone without first stopping medication, you could have a relapse. Regular exercise and a healthy diet will help you stay in good shape while taking this drug. Prednisone is used to treat a variety of conditions including allergies, asthma, chronic obstructive pulmonary disease (COPD), ulcers, diabetes, inflammatory bowel disease (IBD), multiple sclerosis (MS), lymphoma, and various other diseases. It reduces inflammation and immune response to infections.