Both suppress the renin-angiotensin system, so they have similar uses. According to a 2023 research article, this system controls the heart, blood vessels, and kidney functions by regulating blood vessel tone and salt and water balance.
However, the two types of medications work in different ways. ARBs prevent angiotensin II from connecting to some of its receptors. In contrast, evidence indicates that ACE inhibitors stop the conversion of the precursor angiotensin I to angiotensin II.