To perform basic simulations, at a minimum, the following data is needed:
One dataset from a screening experimental design, containing sufficient variations in growth
Data should show batch evolution (data over time)
In .csv or Excel format
Required variables: Batch ID, time, viable cell density, viability, volume
Optional variables: Process inputs (e.g. DO, pH, temp), metabolites (e.g. glucose, lactate, glutamate), titer, feed, media composition
Using larger datasets will unlock more advanced simulations and is needed to adapt the models to other mammalian cell lines.