Advantix should be removed from the pet's skin with a mild dish detergent, according to the veterinarian. Wash the dog's skin with a soft washcloth and water after applying the dish detergent. It will help to prevent further irritation. The Advantix should be washed away completely by keeping your dog rinsing with water. Make sure not to scrub or agitate the skin too much when doing this as this may cause further irritation. In some cases, you will find that the majority of the product has been removed but there is still some residue left on your dog's fur. To remove all residue from your dog, you will need to shave him again.