Two studies have explored the effects of retatrutide on blood pressure. In a Phase 1 trial with healthy subjects, retatrutide led to weight loss, increased insulin levels, and a decrease in systolic blood pressure. Another Phase 1 study involving patients with type 2 diabetes showed that retatrutide resulted in lower systolic and diastolic blood pressure compared to a placebo. These findings suggest that retatrutide has potential in improving blood pressure, particularly in individuals with obesity or type 2 diabetes. Further research is needed for a comprehensive understanding.