Botox and Juvederm are both used to soften lines and wrinkles thus rendering a refreshed appearance. The difference between these two innovative anti-aging injectable treatments are due to their respective physiological properties and mechanisms of actions. Botox (a neuromodulator) injections relax specifically targeted muscles thus softening and over time eliminating unwanted lines and wrinkles. Juvederm is a hyaluronic acid dermal filler, which when injected into specific tissue compartments of the skin acts to restore lost volume thereby ironing out lines, wrinkles and folds.