Yes, a peripherally inserted central catheter (PICC line) will most likely need to be inserted into your arm to administer some of the intravenous (IV) antibiotics. A PICC line enables medical staff to administer various treatments through one access line. More than one antibiotic can be given at once, for example. Large volumes of fluid can be administered. Some blood draws can be done through the same line. If you will be receiving sedation for the PICC line, you must fast for 8 hours before the procedure (no eating OR drinking — even water). Plan your eating schedule accordingly prior to arriving to the hospital. Often, patients with CF will go home with the PICC line in place to complete their IV therapy there. We will work with the home care company to manage your medications and maintain your PICC line. Weekly blood draws will also be done at home and sent to our office. Your nurse will work closely with you in these situations to help you manage your care at home.