Although rare, it is possible to die in your sleep from anaphylaxis if a severe reaction occurs and is not promptly treated. This underscores the importance of recognizing the symptoms of anaphylaxis, having an emergency treatment plan in place, and carrying an epinephrine autoinjector if you have a history of anaphylaxis or severe allergies. Early intervention can help prevent fatal outcomes and ensure the best possible outcome for those experiencing anaphylactic reactions.