Yes, in case the product design specifies the use of pre-cut gasket as a shim, LOCTITE Anaerobic Gasket Dressing can be used in conjugation with the pre-cut gasket. Just clean the flange surfaces and apply LOCTITE Anaerobic Gasket Dressing to both the sides of a fresh pre-cut gasket. Make sure to use a primer on both the sides of the pre-cut gasket before application of the Gasket Dressing.