Check the mattress tufts, boxspring folds, headboard, frame and pictures for any signs of bed bugs like blood spots or eggs. Keep your luggage on the luggage rack (after making sure it has no signs of bed bugs). Don’t store your luggage on the bed or floor. Hang clothes that can be hung and avoid storing any clothes in a dresser. Check travel reviews before visiting a hotel and be careful of those with multiple reports of bed bugs.