No, it’s best not to use Listerine or any mouthwash while wearing Invisalign. We also recommend against soaking your aligners in mouthwash. While you may use mouthwash on your teeth, there are negative effects to using mouthwash on your aligners.
Many types of mouthwash contain dyes and scents that can be soaked into your aligners. This can permanently discolor them. If your mouthwash also contains alcohol, your aligners may become damaged.
If you’d like to soak your aligners in a way that won’t harm them, you can get specialized aligners cleaning crystals. These crystals won’t damage your aligners and make sure they’re squeaky clean.