Yes, the answer is yes. The second layer of thermal pants for women is conceivable and not unheard of, depending on your activity level and the weather circumstances. While it may appear unusual, wearing a second base layer may be appropriate and even beneficial in some conditions. The primary purpose of a second layer is to add another degree of warmth if the first one proves insufficient. So if you're walking in cold conditions, adding another layer is easy enough. If you are skiing or snowboarding, then having one single layer isn't going to cut it. There have been reports of people wearing second layers while hiking in hot climates, but this is not recommended because it increases the volume of clothing you are carrying which is already putting additional strain on your body. It is possible to wear a second layer of thermal underwear for women, however, this is not recommended because the extra thickness of material would not only limit movement but also slow down your skin's ability to cool off. Generally speaking, the more layers you add, the warmer you will be. However, this isn't always the case; sometimes less is more. Sometimes less bulky, lighter materials are all that's required to keep you warm. Other times, a multiple-layer set up with heavy fabrics is needed to achieve sufficient warmth.