No!  The third prong is designed to prevent deadly electrical shock from the electrical item you are using.  The third prong acts as a "ground" so that, if a wire inside the item were to come loose, the plug can help divert the electricity back into your home's electrical system rather than shocking the next person to touch that item.  If the third prong is disabled, there is nothing protecting you or a family member from receiving a nasty shock from the equipment.