Yes! Buttermilk makes baked goods extra rich so you can substitute buttermilk for milk in most baking recipes. It is a 1 to 1 ratio, for example if a recipe calls for 1 cup of milk, you can use 1 cup of buttermilk. And if you use buttermilk then make sure the recipe calls for at least 1/2 teaspoon of baking soda. This helps it to rise properly.