Well, that is entirely up to you, though I personally recommend My Time at Sandrock (and its prequel My Time at Portia) with a passion I usually reserve for big-budget RPGs. It all comes down to what makes you feel a sense of calm and ease as you play. Many of these games are cheap and you can even find some free cozy games on the list, so by all means, try a few and see what you like. You might find joy in the simple pleasures of tending a garden or running a shop in a fantasy land. You might prefer mining resources, or building elaborate homes full of random knick knacks and personal treasures. Or maybe running around as a cat is right up your alley.