Too little endorphins may result in increases in aches and pains, depression, anxiety, mood swings, and addiction. Studies in individuals with post-traumatic stress disorder (PTSD) are shown to have a disturbed beta-endorphin system. Without a normal endorphin response, the study participants had more symptoms of hypo-arousal, anxiety, and depression. Research also interestingly shows that people who suffer from migraines have low blood levels of endorphins.