A Chief Marketing Officer (CMO) and a Fractional CMO differ in terms of their employment structure and the extent of their involvement with a company. While a traditional CMO is a full-time, in-house executive responsible for the overall marketing strategy of a company, a Fractional CMO offers a more flexible and temporary solution, bringing specialized expertise on a part-time or project-specific basis. Fractional CMOs are often utilized by smaller businesses or organizations that may not require a full-time executive but still need strategic marketing guidance.