No, creatine is not a protein and creatine supplements are not the same as protein powder supplements. However, both can be used to support lean muscle mass and strength, in different ways. Creatine is a naturally occurring substance in animals and humans that’s made from several amino acids, which are the building blocks of protein. Proteins contain long chains of many types of amino acids.  C reatine supplements are used to increase energy in muscle tissue, which boosts exercise performance and strength. Protein, whether sourced from food or supplements, supplies your muscles with the amino acids needed to support muscle growth and recovery.