Other skin lightening agents may improve the appearance of melasma.  Topical agents such as kojic acid, arbutin, and Vitamin C are available in cosmeceutical products (sold as skin brightening pads Craig Singer MD  Dermatology) and are safe for long-term use. Tranexamic acid, commercially sold  topically as Lytera through CSD is a newer topical agent with skin lightening properties. Azaleic acid (Finacea TM) is  available as a prescription which may also be of benefit and is felt to be relatively  safe during pregnancy.  The use of glycolic acid pads 10% or 20% (sold at Craig Singer MD Dermatology)  helps exfoliate the skin and disperse pigmentation thereby lightening the overall  skin complexion.