No, there is no difference between fried chicken and Southern fried chicken - they are both the same thing.u003cbr/u003eu003cbr/u003eBoth of these things are chicken that is wrapped in a crispy coating due to being air-fried, pan-fried, deep-fried, or pressure-fried. u003cbr/u003eu003cbr/u003eThe crispy batter helps the chicken to retain its moistness so the meat is tender and juicy when bitten into.