Crosslinking of the filaments by specific motors or multivalent binding proteins (accessory proteins) increases stability and forms higher-order structures.
Examples of higher-order cytoskeleton structures include contractile bundles (muscle cells), the microtubule organizing center (MTOC), the nuclear lamina and the intermediate filament-based ‘cage’ that forms around the nucleus from flexible cables at the cell surface to the center of the cell… Read more…