Not really! Mouth protectors are constructed to protect your teeth from any damages. But, yes, remember that you must pick a mouth guard that comfortably sits on your teeth. It must fit you right and should not hinder your daily life. Also, note that sometimes you might experience soreness in your jawlines, particularly if you wear the mouth protectors while sleeping or for the first time. So, the mouth protectors do not damage your teeth but in turn, protect them only if you pick them right.