Hydrocortisone can be used at the same time as antifungal treatments such as miconazole and clotrimazole, but you shouldn’t try to use them both at once without speaking to your doctor or pharmacist first.
They will probably recommend that you use a product which already contains both active ingredients in the right proportions, for example, Canesten HC cream contains clotrimazole and hydrocortisone in one cream, and Daktacort contains hydrocortisone and miconazole in one cream.
If you have thrush or a fungal infection, HC cream won’t be enough to clear your infection alone, so your doctor may recommend one of these creams instead.
They use the anti-inflammatory and anti-itch properties of hydrocortisone, and the anti-fungal properties of miconazole or clotrimazole all in one, easing symptoms and treating the cause of your infection at the same time.