Yes, however stereo headsets are recommended when using the GMA-350. Using a monaural headset in a stereo jack shorts the right headset channel output to ground. While this does not damage the Audio Panel, a person listening on a monaural headset hears only the left channel in both ears. If a monaural headset is used at one of the passenger positions, any other passenger using a stereo headset hears audio in the left ear only.