Botox injections are primarily used to treat moderate to severe fine lines and wrinkles, such as crow’s feet, forehead lines, and frown lines, for which the United States Food and Drug Administration (FDA) approved Botox injections nearly 20 years ago on April 15, 2002. The operative ingredient in Botox injections is onabotulinum toxin A, which is a protein that functions as a neuromodulator. As a neuromodulator, Botox interrupts the nerve signals that cause muscle contractions in the treatment area, due to facial expressions, such as laughing, smiling, or frowning. Repeated muscle contractions, coupled with the gradual decrease in collagen production, are what cause fine lines and wrinkles to appear as we age. As we lose collagen, our skin loses its ability to bounce back from such muscle contractions. As such, Botox injections help the muscles relax so your skin can have a break and smoothen out the lines of age. While Botox is mostly known for its cosmetic uses, it is also FDA-approved to treat various medical conditions, such as upper limb spasticity, strabismus, hyperhidrosis, chronic migraines, blepharospasms, cervical dystonia, and others.