The prognosis for colonic neoplasm can vary depending on the stage and severity of the cancer at the time of diagnosis. In general, the earlier colon cancer is detected and treated, the better the prognosis.Stage I: In the earliest stage of colon cancer, the cancer is confined to the mucosa (inner lining) of the colon or rectum and has not spread to the lymph nodes. Studies show that the five-year survival rate for stage I colon cancer is about 90%.Stage II: In stage II colon cancer, the cancer has spread to the submucosa (layer of tissue just beneath the mucosa) but has not reached the muscle wall of the colon or rectum. The five-year survival rate for stage II colon cancer is about 70%.Stage III: In stage III colon cancer, the cancer has spread to the muscle wall of the colon or rectum, but has not spread to the lymph nodes. The five-year survival rate for stage III colon cancer is about 50%.Stage IV: In stage IV colon cancer, the cancer has spread to the lymph nodes, distant organs, or other parts of the body. The five-year survival rate for stage IV colon cancer is about 10%.It is important to note that these survival rates are based on overall averages and can vary greatly depending on individual factors such as age, overall health, and the specific characteristics of cancer. Early detection, proper treatment, and follow-up care can significantly improve the prognosis for colonic neoplasm.