Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. * As per my clinical experience, the severe muscle cramps involving calf are known side effect of angiotension II converting preparations via alterations in potassium levels. I recommend to call your doctors office and discuss the same, as you require change of molecule instead of Valsartan. Hope I have answered your query. Let me know if I can assist you further.