Both are fillers that use hyaluronic acid to plump the skin. The main difference between Juvederm and Restylane is that Juvederm tends to spread out a little after it’s injected, while Restylane stays more in place. Although this creates some minor pros and cons between Juvederm vs Restylane, they usually make more of a difference to the treatment provider than they do for you as a patient. If you aren’t sure whether Restylane or Juvederm might be better for you, talk with our provider during your consultation.