Yes, there are studies suggesting that ozone can increase the production of Type 1 collagen, which plays a critical role in dental health. One study from 2015, published in Dentistry, suggested that “clinical use of ozone would facilitate the positive balance between HGF-mediated periodontal tissue maintenance and repair and the stimulation of inflammation and tissue degeneration following exposure to microbial pathogens.” If you're concerned about your collagen levels, check out my list of the best collagen supplements.