Gentle dish soap or laundry detergent and warm water are usually all it takes to clean a pack 'n' play and its floor pad. You can scrub the surfaces by hand with a sponge, rag, or brush, or you can fold the pack 'n' play and soak it in the mixture in your bathtub for a couple of hours. Hose down the pack 'n' play afterward and allow it to dry completely before use.