This trips up a lot of folks. The simplest answer is this: THC gets you high, while CBD does not. THC and CBD gummies come from the same plant family, but they target different systems in the body. CBD gummies interact with your endocannabinoid system, often offering relaxation and pain relief without psychoactive effects. The main difference between THC gummies and CBD gummies lies in their psychoactive properties, with THC causing a high and CBD not.