It’s important that you consult local regulations governing small businesses of any description. In many cases, though, you do not require a business license to set up an online jewelry store to sell your products. In some regions, you may need a tax number, but this also may depend on how much income you’re generating. Consult an accountant and/or business lawyer while in the process of establishing your business. Don’t forget to ask about business insurance and any other legal requirements.