Absolutely, setting permissions and roles is a critical step in enhancing the security of the collaboration process. Assigning different levels of access to various users ensures that sensitive information is only accessible to authorized coworkers. Customizable permission settings offer an additional layer of security, enabling you to control who can view, edit, or share specific documents. This is particularly important when collaborating with people both within and outside your organization, as it allows for a more secure and controlled sharing of information.