The American College of Allergy, Asthma, and Immunology (ACAAI) and the American College of Obstetricians and Gynaecologists (ACOG) recommend using pseudoephedrine (a drug contained in Sudafed) during pregnancy. But they are against the use of oral decongestants in the 1st trimester. During those first months, oral decongestants could increase the risk of abdominal wall defects (gastroschisis).