The difference between high and low fidelity wireframes primarily lies in their level of detail and functionality. A low-fidelity wireframe, often crafted with simple tools, offers a basic, skeletal illustration of a product's layout and user paths, without intricate aesthetic features. In contrast, a high-fidelity wireframe delivers a rich, detailed, and interactive design that closely mirrors the final product. It's created using advanced digital wireframing tools and typically incorporates actual content, color schemes, and refined UI components.