Basis of DifferenceNucleus NucleoidDefinitionEukaryotes have a "nucleus" that stores their Genetic information.Prokaryotes have a nucleoid that stores their genetic material.SizeLargeSmallChromosomesSeveral chromosomesOnly one chromosomeShapeSphereIrregularMembraneDouble layer membraneNo membraneNucleolusIt is present hereIt is not present hereNucleoplasmIt is present hereIt is not present hereCompositionThe main composition are DNA, histones, RNA, enzymes, dissolved ions, and other subnuclear bodiesDNA, histones, RNA, and other proteins.