Like most supplements, Reishi products have certain contraindications. Taking Ganoderma lucidum during pregnancy, breastfeeding, and childhood it is not recommended as no studies have confirmed its safety in these life stages. In addition, Reishi mushrooms are contraindicated in the following situations:
Consumption of immunosuppressant drugs. Reishi compounds may decrease the effectiveness of these treatments.
Intake of blood-thinning medication, such as warfarin. Ganoderma lucidum could increase the risk of bleeding.
Individuals who are about to undergo surgery, as Reishi can increase bleeding.
Consumption of antihypertensive drugs. The combination of Ganoderma lucidum with antihypertensive drugs could lower blood pressure below normal values.
Diabetic individuals who take oral glucose-lowering medication or insulin. The effect of the drug added to the hypoglycemic activity of Reishi mushrooms could lead to hypoglycemia (blood glucose levels below normal).