According to some studies, melatonin also inhibits the programmed cell death that coronaviruses cause, which can cause considerable lung damage. In addition, coronavirus induces inflammation in the lungs, necessitating inflammasomes' involvement. Melatonin inhibits these inflammasomes' activity: anxiety and sleep deprivation lower overall immunity. However, the current research on the effects of Melatonin on COVID-19 is still in its beginning stage. A few randomised controlled trials (studies assessing melatonin in people) are ongoing. Therefore, at this time, it is too early to say whether melatonin is beneficial for COVID-19.