That's a great question! A case study of liposomal glutathione (GSH) showed that GSH levels increased 28-40% after 1 week's intake of 500 mg dose. However, this study only had 16 patients without a placebo control group, making the results less reliable. A clinical trial of capsule GSH in 54 adults for 6 months showed an increase of 17-29% GSH levels. If you look at the "other ingredient" of the liposomal product, it contains lots of phospholipids and other additives that your body doesn’t need. You get 450 mg of glutathione by taking 5 mL serving (~5 g). Yes, it might have better absorption, but you also get way more other stuff that your body doesn't need. We prefer the capsuled powder glutathione as I get fewer "other ingredients'' for the same dosage, with comparable efficacy.