A leuprolide stimulation test is done in a similar way as the GnRH stimulation test, except that it uses an analog of GnRH (leuprolide acetate) instead. The results are also interpreted similarly: a positive result occurs when the LH level rises above 20 IU/L. However, since this drug remains active in the body for a longer period of time than GnRH, a leuprolide stimulation test may be more sensitive in detecting early signs of central precocious puberty.