Xeomin contains no additives, which is a significant distinction between these two botulinum injections. This might indicate that, unlike other injections, Xeomin will not cause your body to develop a resistance. On the other hand, Botox requires refrigeration, but Xeomin does not. While refrigeration by itself may not make one product superior to another, it may make Xeomin more accessible. Otherwise, they function similarly, temporarily relaxing specific muscles in the treatment region.