Wetting the wipes with water first is the most comfortable option. Wipe as usual. Dirty wipes are put into a wet bag and then laundered together after a few days. Very simple. It's also a lot easier to use than disposable wipes or toilet paper when potty training a child. Unlike toilet paper, fabric doesn't leave "residue" behind on your body. It also seems to do a better job cleaning you than toilet paper does.