Colon cleanses are most commonly administered by mouth as a powder, tea, or pill. There are cleanses for purchase online that can easily be done from home. Some examples of a colon cleanse regimen include taking 4 capsule supplements before going to bed, taking 3 capsules 1-2 times daily, drinking a formula before bed, and more. Follow the product description for the peak times to take the colon cleanse and for the amount of days to continue the regimen.