The different technical devices used in an experiment often represent large interference factors: for example, mechanical pumps for building up a vacuum or the generated heat and electromagnetic radiation from network and control devices. Conventional experiments only require that individual parameters be shielded, for example the temperature. However, with the measurement developments in nanotechnology, we now have experiments that are sensitive to multiple or all of the interference factors. Temperature, humidity, vibrations, sound, electromagnetic fields should therefore be shielded all at once. These challenges can be mastered successfully only by considering the complete system. This practical application example provides information about the optimal vibration isolation for optical measuring technology.