Yes, it's generally recommended to trim your Thanksgiving cactus to maintain its shape and promote healthy growth. The plant will naturally grow long, trailing stems, so regular trimming can help keep it compact and prevent it from becoming leggy. To trim the plant, use a clean, sharp pair of scissors or pruning shears to carefully cut off any long or damaged stems. Be sure to make clean, diagonal cuts just above a leaf joint, as this will encourage the plant to produce new growth. Avoid trimming off more than a third of the plant's stems at one time, as this can shock the plant and reduce its ability to produce flowers. Regular trimming will help keep your Thanksgiving cactus healthy and promote more abundant blooms.