CRI Naturals, Estrovive’s manufacturer, states that Estrovive can be a safe product, but individuals should consult a doctor before using it with another product.
According to the FDA, dietary supplements may contain ingredients that may affect how medications work, as they may reduce their effectiveness. There is no guarantee that herbal products will not interact with other medications.
The American Heart Association states that a person taking blood pressure medication should avoid taking licorice, one of the ingredients in Estrovive's formulation. Licorice has hypertensive effects, so it may interfere with antihypertensive medications.