Yes, you can have an FSA with a HDHP. However, having a HDHP makes you eligible to contribute to a health savings plan (HSA), which may offer even greater benefits. You cannot contribute to an HSA and an FSA at the same time, unless your flexible savings plan is limited purpose (LPFSA). If you have an HDHP, consider whether it’s in your best interests to contribute to an HSA (with or without an LPFSA), or whether a general health FSA will be enough to meet your needs.