The main difference between the Vitamix Pro 750 and the 7500 lies in their settings. My Pro 750 has pre-programmed settings for added convenience, while the 7500 does not. The 7500 also doesn't have the "pro" label. That being said, they both have a 2.2 HP motor and come with identical accessories and warranties. The 7500 model is typically for sale $50-100 lower than the Pro 750.