Since ototoxic drugs are a contributor to both acute and chronic tinnitus, it’s good to know which drugs to watch out for. They can be divided into three groups:
Group One includes aspirin at high doses as well as other salicylates like: Amikacin, Amphotericin B (Fungizone), Bumetanide (Bumex), Carboplatin (Paraplatin), Chloroquine (Aralen), Cisplatin (Platinol), Ethacrynic acid (Edecrin), Furosemide (Lasix), and Hydroxychloroquine (Plaquenil).
Group Two includes the analgesic Ibuprofen (Advil) and the tricyclic anti-depressant Imipramine (Tofranil), along with Chloramphenicol (Chloromycetin), lead, and quinine sulphate.
Group Three includes alcohol, toluene, and trichloroethylene, as well as Chlordiazepoxide (Librium), Chlorhexidene (Phisohex, Hexachlorophene), Ampicillin, Iodoform, Clemastin fumarate (Tavist), Chlomipramine hydrochloride (Anafranil), and Chorpheniramine Maleate (Chlor-trimeton and several others).