The world's busiest flight routes in 2022 (by number of seats) Hanoi-Ho Chi Minh City 10,605,579. Tokyo-Fukuoka 10,426,245. Melbourne-Sydney 8,204,871. Riyadh-Jeddah 7,495,790. Okinawa-Tokyo 7,343,199. Denpasar-Bali-Jakarta 7,100,224. Mumbai-Delhi 7,000,015. Tokyo-Osaka 6,231,151. More items... Jan 20, 2023