Before your baby uses a new NUKpacifier for the first time, sanitise the pacifier by boiling it in water for 5 minutes. For daily cleaning, wash with hot water and mild detergent, then rinse clean. NUK pacifiers are dishwasher-safe, top rack only. Water may get inside the nipple during cleaning, and can be removed by squeezing the nipple. For hygiene and safety, replace pacifiers after 2 months of use.