One of the most serious risks associated with Aubagio (teriflunomide) is related to liver damage and drinking alcohol may increase this risk. It is usually recommended that you should limit your alcohol consumption or avoid drinking altogether. Your doctor will perform liver enzyme tests before you start taking Aubagio and periodically throughout the first six months of treatment. You should speak to your doctor about your personal risk of liver problems and whether it is safe to drink alcohol. If you do drink alcohol while taking Aubagio and have signs of liver problems, you should contact your doctor immediately. These signs include: Nausea Vomiting Stomach pain Loss of appetite Tiredness Yellowing of your skin or white of your eyes Dark urine