Yes, though which teams you can bet on depends on the state in which you live. Some states (like New Jersey) do not allow residents to bet on in-state schools at all. Others (like Massachusetts) only allow residents to be on in-state schools' futures (not single games). While some (like Colorado and Ohio) do permit single-game betting on in-state schools. Everyone who lives in a legal sports-betting state can wager on single games for out-of-state teams in March Madness.!