The costs associated with blood disorder treatments vary widely. While most of the drugs used for blood disorders are relatively affordable, some are not. The cost for medications to treat hemophilia costs an average of $270,000 annually, although when complications arise, the cost can rise to as much as $1 million. An insurance denial for a blood disorder treatment like a bone marrow transplant can be devastating. A bone marrow transplant can cost as much as $95,000 or more, while a blood transfusion can cost $3,000 or more.