Yes, apple cider vinegar can interact with various medications, particularly those for diabetes, high blood pressure, and high cholesterol. It may affect drug absorption or increase the risk of low potassium levels. Always consult your healthcare provider before incorporating ACV into your routine if you take any medications.Yes, apple cider vinegar can interact with various medications, particularly those for diabetes, high blood pressure, and high cholesterol. It may affect drug absorption or increase the risk of low potassium levels. Always consult your healthcare provider before incorporating ACV into your routine if you take any medications.