Saypha is biodegradable, which means that the effect is not permanent due to the natural degradation of hyaluronic acid. Results can last several months, up to a year, depending on the Saypha product used, the area treated, and the individual's metabolism of the implanted HA. Saypha Filler is expected to last between 6 and 12 months, Volume between 12 and 16 months, Volume Plus between 12 and 18 months. After the mentioned interval, you can decide again if you want further treatment.