The early stages of treatment with allergy shots will be the most expensive part, as you will have to pay for the allergy testing, and then the vials containing your specific allergens in their correct concentrations that is enough to have injected weekly for around 6 months (this exact timeline varies from person to person depending on the recommended immunotherapy). This means that most patients can expect to pay at least $1,000 in the first year to cover the costs of the initial vials and tests, but once the shots have evolved into the maintenance phase (injections administered every two weeks or monthly to prolong the results provided from the initial weekly shots), costs will drastically decrease as the vials will start to last much longer. Many health insurance providers will be able to offer at least partial coverage, so it is always recommended that you check with your provider and the clinic from which you will receive the allergy shots for a more accurate total cost estimate.