The FDA authorizes over 99% of expanded access requests it receives. If the application is denied, FDA will notify the physician. The notification will be followed by a written letter that provides the reasons for FDA's denial of the request.f approved, a number will be assigned to the application. The IND sponsor (treating physician) should provide this IND number to the drug supplier, so the supplier may ship the drug to the treating physician. Typically FDA responds to these requests in a matter of days (or hours for emergency requests). You must also receive IRB approval before treatment can begin unless it’s an emergency request.