Technically, you can count cards in Let It Ride. However, you won’t gain an advantage over the house with Let It Ride card counting.
Blackjack is the only game that gives you a true advantage when counting cards. Assuming you’re interested in advantage play, then you should try land-based blackjack.
Let It Ride is a strategic game. Therefore, you must use proper strategy to boost your odds of winning.
You still won’t have as good of a chance to win with Let It Ride as you will with baccarat, blackjack or French roulette — the highest-paying casino table games. However, the 96.49% RTP that you achieve with perfect strategy ranks well in comparison to many other casino games.