Yes. Dust mite mattress covers are designed to prevent dust mites from infesting mattresses and can be effective in reducing the number of dust mite allergens in a mattress. However, they should be used in combination with other measures, such as dust mite-proof covers for pillows and comforters and washing of bedding, and keeping humidity levels low, to effectively reduce dust mites in the home.
For additional information check out "Do Dust Mite Covers Really Work" in our resource center.