Yes you can. To freeze follow directions and assemble casserole as directed but do not bake. Allow the pasta and sauce mixture to completely cool then place in a 9x13 freezer-safe dish, cover tightly and freeze for up to 2 months. Thaw in the refrigerator for 24 hours before baking. If using glass be sure to follow the manufacturers instructions for freezing and baking to prevent the dish from shattering or breaking due to temperature changes.