The World Health Organization (WHO) has studied CBD in-depth, including medical literature. WHO found that CBD has low toxicity and the abuse potential insignificant. One reason is that a study showed that even a high dose of 600 mg of CBD did not produce psychotic or intoxicating symptoms. Since CBD does not produce a high, it makes it much more unlikely someone would even try taking too much CBD. Another study found that oral CBD did not lead to abuse even in frequent marijuana users.