Yes, several factors can trigger hypothyroidism. One of the most common causes is Hashimoto's thyroiditis, an autoimmune disease where the body's immune system mistakenly attacks the thyroid gland. Other triggers can include certain medications, radiation therapy to the neck area, and thyroid surgery. Severe iodine deficiency can also cause hypothyroidism as the thyroid gland needs iodine to produce thyroid hormones. Moreover, certain conditions such as Turner syndrome, a genetic disorder in women, can increase the risk of developing this condition. Stress and pregnancy are other possible triggers. Understanding these triggers can help in the early detection and treatment of hypothyroidism. Remember, if you detect any signs, it's important to consult with a specialist like Dr. Nassar MD in Redlands, CA, for a comprehensive diagnosis and treatment plan.