Research is still being performed to understand exactly why and how Ketamine for depression is so effective. The current understanding is that Ketamine binds to receptors in the brain that increases the amount of a neurotransmitter called glutamate that is released. This then sets off a chain of reactions within the brain that affects thinking and emotional regulation. Glutamate is also associated with regrowth and regeneration within neural synapses.In simple terms, the brain reacts to Ketamine in a way that triggers hormones that help create feel-good emotions. This effect also occurs quickly after a person receives their treatment, but some people may need several treatments before they experience the highest level of benefits. It also works to help the brain to regrow neural connects that help patients to continue to thrive.