I would say "yes," with a caveat. I've done this trip on a hybrid bike, which was fine, and on an e-bike which was also enjoyable. I've seen plenty of road bikes on this section of the trail, but it was never something I wanted to try myself on a bike with 23" wheels and no shocks whatsoever. Ouch! When it comes to e-bikes, I don't know that there's any kind of rule or enforcement for what types of ebike you might use. Class 1 bikes would be fine. If you have a bike that will assist you at higher speeds, I'd recommend you slow down -- both for your own enjoyment of your ride and for the safety of other people on the trail. I was worried about my e-bike not being able to make the trip both directions on one battery charge as it has the annoying tendency to tell me that I have an estimated "23 miles left" (for example) on Eco mode. What I found was that I only used one bar or charge, kept the bike motor off or on Eco most of the time, and could have gone both ways in a single day on one charge.