As others have already said, Charlotte was so named in the 1760s by pro-British colonists who wanted to curry favor with Englandu2019s King George III by naming the new town after his wife, Queen Charlotte Sophia, originally of Mecklenburg-Strelitz, Germany. The county where Charlotte is located is Mecklenburg County.These days, it seems as if you only occasionally hear Charlotte called the Queen City. For one thing, itu2019s such a common appellation u2023 there are are 30 or 40 towns and cities in the U.S. alone that are nicknamed the Queen City. So, itu2019s not a very distinctive name. It doesnu2019t have the branding power of names like the Crescent City, the Windy City, the Big Apple or the City by the Bay.