No, it is not possible to fatally overdose on marijuana. Unlike other substances such as alcohol or opioids, cannabis does not depress the central nervous system to the point of stopping breathing or heart function. However, consuming too much marijuana can lead to unpleasant side effects such as anxiety, paranoia, and rapid heartbeat. Ingesting high levels of THC (the psychoactive component in marijuana) can also result in symptoms such as hallucinations or delusions. Additionally, ketamine can also have sedative effects that make it appealing for individuals looking to escape from their thoughts or emotions. This can lead to a pattern of self-medication and reliance on the drug to manage mental health issues, contributing to addiction.