Once or twice a day you can drop/spray our spagyric tinctures directly under your tongue/into your mouth or mix with Spagyri-Zyme or water. Then hold under the tongue until body temperature before swallowing. It does not matter if you take them with or without food. Unless otherwise indicated, you can mix most of our spagyric tinctures to take simultaneously. Wait 5-10 minutes before or after taking spagyric tinctures to take our liposomal products.