Some Restylane products are formulated with Lidocaine to further enhance the patient experience. However, even those that do not have Lidocaine directly in their base can be comfortable. Prior to injections, topical numbing gel can be applied to the skin for a few minutes. Because we use a very small needle for filler injections, most patients find treatment to be very tolerable. At most, a momentary pin-prick is what most patients describe.