Fertility declines with increasing female age, beginning as early as the late 20’s and early 30’s, and is most pronounced in women over 35. This is believed to be related to a decline in ovarian reserve and a higher incidence of oocyte (egg) abnormalities. The decline in fertility is accompanied by an increase in the rate of miscarriage. Evaluation and treatment of infertility should not be delayed in women over 35 who have attempted conception for over 6 months.