Yes, the Milan Cathedral has been damaged by natural disasters. In May of 1805, a strong earthquake caused significant damage to the cathedral and its surrounding area. The quake destroyed many of the spires and towers of the cathedral, as well as causing structural damage to several other churches in Milan. In November 2018, an intense windstorm caused further damage to the cathedral’s facade. Pieces of stonework were torn off and some parts of the façade were cracked or otherwise damaged. These damages have since been repaired but serve as reminders that even such grand structures can be vulnerable to nature’s wrath.