The key to a successful aloe vera soil mix is proper drainage. With its desert origins, aloe prefers dry conditions and is easily susceptible to root rot if overwatered. A well-draining soil mix containing elements such as sand, perlite, pumice, and pine bark fines is ideal for aloe vera plants. Additionally, these plants do best when grown in a neutral to alkaline pH, ranging from 7.0 to 8.5, but can tolerate slightly acidic soils.