Technically yes, however, it's not my top choice. Using a double boiler ensures the candy melts melt at a consistent temperature slowly and evenly with a smooth finish. If you do choose to use the microwave, use low heat (or the defrost setting) to avoid overheating and having the chocolate seize. Microwave for 30-second intervals, stirring in between each one. Once it is almost fully melted, remove it from the microwave and stir until smooth.