Whenever we place anything in our mouth, it sends a message to our salivary glands to produce saliva. When you start to use ApneaRX, it can cause excess salivation due to activation of the salivary glands. You need to repeatedly swallow the saliva when you start using ApneaRX. In a few days to a week, your mouth adjusts to the device, and the excess salivation slows down.