This depends on how much Carolina Reaper you eat. The most common side effect is pain. For some individuals, hiccupping occurs as the phrenic nerve is irritated. Other mild effects are sweating and salivating. If you ingest a whole pepper, you will feel the pepper moving through your stomach and gastrointestinal tract for some time. This will usually last a few hours where you will have a warm sensation in your belly. If you ingest a larger amount most people will feel an endorphin rush, this is very similar to a runner’s high. (How you feel after running long a distance) If you have ulcers, you should not eat the pepper as it may irritate them. If you eat a large amount, you may experience cramping and bloating. You may also experience pain as the pepper leaves your body. Everyone is different, if you commonly eat hot peppers the effects will usually be milder.