In general, women start thinking about facelifts in their late forties to early fifties. Around this age our facial features undergo significant changes. There is volume loss, and as the fat that’s left in the cheeks starts dropping down, this creates deeper nasolabial folds (the ‘smile lines’ that run from the nose to the mouth). Ultimately, this dropping effect continues down to the jowls, which squares off the appearance of the face. - plastic surgeon Dr. Michael Frederick, Palm Beach Gardens, FL