If you give your baby the proper dose of gripe water wait fifteen to thirty minutes before determining if it is working. The Gerber Soothe product can take up to one week to work at its full potential. If you have waited and your baby is still very fussy it could be something other than tummy issues bothering them. Check their temperature and make sure they are comfortable. Get the baby a clean diaper. If this is a lasting issue and you feel like it could be more than minor tummy troubles or typical colic symptoms visit your doctor.