In many cases, blackhead and whitehead treatment is generally the same. Topical antibiotics like benzoyl peroxide have long been used to help treat and prevent new comedones from forming. Other medications like retinoids and corticosteroids are used by dermatologists to help with blackhead and whitehead treatment, but there are many available options. If you're not sure which acne treatment is best, a dermatologist can help you figure out which one is right for you.