Our fresh primary model is extremely well differentiated and representative of in vivo proximal tubule
Our flagship model, aProximate is supported by a large package of validation data to support its use in transporter and nephrotoxicity assays and its value in predicting in vivo outcome. It is available across the main preclinical species (rat, dog, NHP and mouse) together with human to allow comparative studies.
It has been used in regulatory submissions to support NDA and IND submissions
If you choose to outsource to us, the service is performed in state of the art laboratories by experienced scientists working to strict SOPs and a Quality Management System.