If left untreated, bipolar disorder can lead to longer and more severe mood changes. For example, episodes of bipolar-related depression can last up to 6 months, while manic episodes can last up to 4 months without ongoing treatment. Someone living with bipolar disorder may also have a higher risk of the following: substance abuse (for example, alcohol or drugs) anxiety heart and cardiovascular conditions diabetes unhealthy weight (such as obesity) suicidal thoughts Some of these problems may need to be managed at the same time as bipolar disorder. With the right treatment and support, most people with bipolar disorder can live productive and fulfilling lives.