To ensure your jewelry making supplies are safe and non-toxic, check that all materials are free from harmful chemicals such as lead, nickel, and cadmium. Look for products labeled as hypoallergenic and compliant with safety standards. Reputable brands often provide detailed information about the safety of their materials. You can also look for certifications such as CPSIA (Consumer Product Safety Improvement Act) compliance. If in doubt, research customer reviews and brand reputation to confirm the safety and quality of the supplies.