Yes. For instance, the way you fluff down pillows will be slightly different from the way you’d fluff alternative down or fiberfill. Down pillows cannot be heat-dried. They have to be put into the dryer on a no-heat cycle or air-dried only.
And while you can fluff shredded foam pillows, solid foam pillows like latex or memory foam pillows can’t be machine-washed or fluffed at all. They don’t have redistributable stuffing.