Invokana contains the drug canagliflozin, which is a sodium-glucose co-transporter 2 inhibitor. Invokana is used with diet and exercise to improve blood sugar levels in adults with type 2 diabetes. It’s also used to reduce the risk of heart attack, stroke, and death in adults with type 2 diabetes and heart disease. In addition, it’s used to reduce the risk of certain complications of diabetic nephropathy (kidney damage that’s caused by diabetes).
Invokamet contains two drugs: canagliflozin (the drug in Invokana) and metformin, a biguanide. Like Invokana, Invokamet is used with diet and exercise to improve blood sugar levels in adults with type 2 diabetes. However, it’s not approved to reduce the risk of heart-related problems such as heart attack or stroke in people with type 2 diabetes and heart disease.