Your first visit to a certified SPRAVATO treatment center will be a consultation. The treatment center will receive your medical information from your healthcare provider, conduct its own assessment to determine if SPRAVATO may be right for you, and verify your insurance information as part of the eligibility confirmation. If SPRAVATO is recommended, the treatment center will build a treatment plan with you and enroll you in the SPRAVATO Risk Evaluation and Mitigation Strategy (REMS) Program. You may start treatment on your next visit. You may also be able to get help with insurance matters, scheduling and treatment preparation. On treatment days, you will administer SPRAVATO nasal spray yourself under the supervision of a healthcare provider at the treatment center, who will assess your blood pressure before and after you administer SPRAVATO nasal spray. Watch Instructional Video After you administer SPRAVATO nasal spray yourself, there will be an observation period of at least two hours during which you will be allowed to rest comfortably while a healthcare provider monitors you for possible side effects. More About Observation Because of possible side effects affecting mental alertness and motor coordination, you won’t be able to drive, operate machinery, or do anything where you need to be completely alert until the next day, following a restful sleep. So you’ll need to plan for rides on treatment days. Tell your healthcare provider if you have any side effect that bothers you or does not go away.