Hey, Dude shoes are machine washable. We usually just put them in a lingerie bag and use gentle soap and cold water, but you can throw them in the washer and dryer for best results. If you don't want to do that, we suggest using either vinegar or baking soda to remove any odor from your shoes. Vinegar works well to remove the odor from sweat and baking soda is great for removing food spills. The combination of vinegar and baking soda will give you a fresh, clean Hey Dude shoe every time!