If your vape contains nicotine, especially a high percentage, it could lead to skin problems. Nicotine causes dehydration and decreases the amount of oxygen in your blood, leaving the skin prone to acne and other skin issues. To avoid these issues, you can gradually decrease the amount of nicotine in your e-juice before switching to a nicotine-free option. The associates at your local Kure store can help you with this process.