Mass spectrometry instruments used in numerous applications, which include prescription drugs, scientific diagnostics, and environmental evaluation, are subject to regulatory requirements. Depending on the specific application, instruments may need to comply with standards and guidelines set by regulatory bodies, which include the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMA), and the International Conference on Harmonization (ICH). Compliance with those policies guarantees the accuracy, reliability, and reproducibility of outcomes generated through mass spectrometry units.