No, I wouldn't recommend it! Butternut squash is in the winter squash category, along with acorn and other heartier varieties. It takes a lot longer to cook than yellow. On the other hand, yellow squash and zucchini are considered summer squash, and they're softer, with higher water content. They don't take as long to cook, taste great against gooey cheese, and perfectly complement the buttery stuffing on top!