Every binding is designed to adjust to fit the sole length of your boot. While some bindings let you make small length adjustments, say 6-10 mm, others only allow for more minor adjustments to accommodate boot fit to the original mount.
If you do alternate boot sizes, consider a binding like the Marker Alpinist that gives you 15 mm of adjustability, so you can use boots with different sole lengths. That said, this should truly be done at a shop to ensure that the bindings are adjusted exactly to your sole length and that DIN has not been compromised.
Your binding DIN settings take several factors into account, including your boot size, the terrain you ski, your height and weight, and your level of experience. While you can make small adjustments on your own, you should go to a certified ski technician to mount your bindings and make major adjustments.
Bindings have a range of about 25-30 mm of adjustability to allow you to change boot size a little bit up or down. Brands in the same shoe size can vary 3-5 mm in length difference, so your binding will accommodate that.