As a cultural centre, Spain has more than a thousand museums all over the country, with many concentrated in the big cities of Madrid and Barcelona. The Museo Nacional del Prado in Madrid opened to the public in 1819, starting with 1,510 paintings from the royal collection and which grew throughout the centuries. Highlights include The Garden of Earthly Delights by Bosch, The Nobleman with his hand on his Chest by El Greco, Self-portrait by Dürer and The Family of Carlos IV by Goya. Also in Madrid are Reina Sofía, a museum of contemporary art; and Thyssen-Bornemisza Museum, which began as a private collection of Heinrich Thyssen, a German-Hungarian art collector. The Picasso Museum in Barcelona, opened in 1963, focuses on the formative years of the Spanish artist Pablo Picasso (1881-1973), carrying a collection of his early paintings and more than 4,000 pieces in its permanent collection. Also in Barcelona is the National Art Museum of Catalonia; highlights include a collection of Medieval Gothic Art and work by the city’s most famous architect, Gaudi. Outside these two cities are the Guggenheim Museum in Bilbao, a museum of modern and contemporary art, and the Dali Theatre and Museum in Figueres, hometown of surrealist artist Salvador Dali.