To handle more complex reaction networks or higher-order reactions, the CRDDME model can be extended by incorporating additional species and reaction types. For complex reaction networks, the model can include multiple types of molecules interacting through various reactions such as association, dissociation, and catalysis. Higher-order reactions involving more than two molecules can also be simulated by defining the corresponding reaction rates and interaction functions. By expanding the CRDDME to accommodate a wider range of reactions and species, researchers can investigate intricate biochemical systems with multiple components and reaction pathways.