While Cetaphil Moisturising Lotion primarily focuses on providing hydration and maintaining the skin's moisture balance, some users do find it can help create a smooth base for makeup application. Its lightweight texture is easy to absorb, making it a potential canvas for makeup. To use it as a potential primer, apply a small amount and wait a few minutes before proceeding with your makeup routine. However, if you're specifically seeking a dedicated makeup primer, you might explore other products that cater to that purpose.