Salmon should be cooked to an internal temperature of 145 degrees F when tested with a digital meat thermometer in the thickest part of the salmon. However, keep in mind that the temperature of the salmon will continue to rise another 5-10 degrees F for about 5 minutes after removing it from the air fryer, so it's best to take it out when it's around 135-140°F and let it come up the rest of the way so that it doesn't dry out.