The kinesin superfamily of proteins represents a large class of motor proteins that carry cargo along microtubules. Conventional kinesins move along microtubule filaments in a manner that resembles human walking. This has been described as an asymmetric ‘hand-over-hand’ mechanism where one head domain steps forward ~16.2nm whilst the other head remains stationary. For each step the head domains take, the cargo is moved 8.1nm along the length of the filament and a single ATP molecule is hydrolyzed… Read more…