Definitely. Your integumentary system that includes your skin, hair, and nails, begins to get affected when you smoke regularly. Smoking is known to change the structure of your skin. Smoking dramatically increases the risk of squamous cell carcinoma, which, in common language, is known as skin cancer. Your skin begins to get wrinkles early on. There may even be patches on your skin. Your lips become dark. Smoking increases the likelihood of fungal nail infections. Your nails begin to appear yellowish and brownish with cracks appearing everywhere. Your hair begins to fall. They also get grey earlier. These conditions can be avoided by a timely smoking test, which is very convenient to conduct.