Premenstrual syndrome (PMS) is the name used for a collection of physical and mental symptoms that occur during the menstrual cycle. Symptoms include uterine pain, mood swings, tender breasts, fatigue and disturbed sleep. There is a more severe form of the condition called premenstrual dysphoric disorder, where a person has extreme mental health issues during their menstrual cycle, such as anxiety and depression. Premenstrual dysphoric disorder treatment may consist of antidepressants or injections to control hormones.