Yes, you’ll need a second dose of Phexxi.Phexxi comes as a gel inside single-use, prefilled applicators. Using one of these applicators, you insert the gel into your vagina. You can do this right before sex or within 1 hour before sex.If you have vaginal sex more than once within 1 hour of inserting Phexxi, you need to use an additional dose. Keep in mind that Phexxi is meant to be used before sex. Phexxi isn’t effective for preventing pregnancy if the drug is used after sex. So, make sure you insert a new dose of Phexxi before having vaginal intercourse.