Avis is unique in that in does have a very thorough partnership with many airlines and their loyalty programs. However this means you need to use a specific AWD code which means you can't use another code. As a result, your discount won't be very large. As an example, with Aeroplan, you can use AWD C682300 for 500 Aeroplan miles per booking at an airport or 250 Aeroplan miles off-airport. In the fine print, you'll have to pay an additional Frequent Flyer Surcharge of $0.75 CAD per day, up to $5.25 CAD per booking. Overall, I'd say it's not worth it.