There are certain groups of medications and certain specific medications that can cause discoloration of your teeth. The amount of discoloration varies from drug to drug and from person to person. While teeth discoloration is one side effect to be aware of, it’s generally not a huge consideration when taking these types of drugs that can improve or even save your life. That’s why you should look into the best teeth whitening options when you take one of the following medicines, or any others that your doctor says may discolor your teeth. Amoxicillin (Augmentin), an antibioticCiprofloxacin (Cipro), an antibioticChlorhexidine, a disinfectant/antisepticDoxycycline, which treats acneTetracycline, which treats acne and some respiratory infectionsMinocycline, which treats acneAntihistamines, which help with allergy symptomsAntihypertensive medications, which help treat high blood pressure