Any medicine or medical device can have side effects. Many are unwanted, but some can be beneficial. Some types of hormonal contraception can have side effects, including: irregular vaginal bleeding (spotting) lighter or no periods less painful periods mood changes headaches skin changes Condoms may irritate your genital area. If you have an allergy to latex, make sure you use non-latex condoms. Ask your doctor or pharmacist for more information about the side effects of different contraceptive methods.