Yes, you can delete library cache on Mac. To do so, you should follow these steps:
1. Open Finder and go to the Go menu at the top.
2. Select Go to Folder.
3. Enter ~/Library/Caches and click Go.
4. Select the folders you wish to delete and drag them to the Trash.
5. Empty the Trash.
It is important to note that some applications may not properly function after deleting library cache files, so it is best to delete them only when necessary.