The primary difference here is that while you get a ‘head high’ when you drink alcohol, you get a ‘body high’ when you are high on weed. Being high on alcohol does not open up your thought process or give you a sensory boost in a manner that weed does. Getting high on marijuana alters all your senses and gives you a very different experience. Moreover, the kind of high that you experience on alcohol is all-too familiar but getting high on weed is different depending on which strain of weed you are consuming.