If KMS Pico does not work for your activation needs, there are several steps you can take. First, ensure that you are using the latest version of KMS Pico, as older versions may not support newer software updates. You can also try running the program as an administrator or disabling your antivirus temporarily, as it may block the activation process. If issues persist, consider seeking help on forums or tech support sites, or explore alternative activation methods that are legitimate and comply with software licensing agreements.