There are a few different ways to make 3D games in Android Studio. One way is to use the built-in 3D Game Engine, which is based on OpenGL ES 2.0 and offers a high level of graphics performance. Another way is to use the Native Development Kit (NDK), which allows you to write code in C/C++ and access low-level features of the device's hardware. Finally, you can also use Java Native Interface (JNI) to call native code from your Java code.