Modalert is a generic version of Modafinil, while Armodafinil is the active ingredient found in drugs like Waklert and Nuvigil. One of the main differences between the two is potency. Armodafinil is considered to be more potent than Modafinil because it is the R-enantiomer of Modafinil and requires lower doses for similar effects. This means that, compared to Modalert, Armodafinil-based drugs like Waklert may provide longer-lasting effects and a stronger overall cognitive boost.