According to the American College of Rheumatology, a patient must display at least four of the eleven symptoms for a lupus diagnosis. A butterfly-shaped rash or malar rash on the face. Skin rash/patches Sensitivity to light Ulcers or sores in the mouth and nose Arthritis/swelling of the joints Seizures or symptoms that indicate that the nervous system has been affected Presence of excessive protein in the urine Inflammation of the heart or lungs Low blood cell counts Presence of specific antibodies in the blood Positive ANA test