In the field of computer science, the process of adapting software to the different languages and technical needs of other countries is known as internationalization and localization. These terms are customarily shortened to the numeronyms i18n and L10n, which include only the first and last letters of each word along with a number representing the total of letters between.
Andreessen Horowitz decided to nickname their company using this abbreviated style. There are a total of 16 letters separating the beginning “A” and the ending “z”. The nickname a16z also signifies that the firm is willing to participate in any round of funding, from A to Z.