After a Platelet Rich Plasma Therapy session, the injection site will remain covered. Keep the surrounding area clean and dry for the next 28 hours. Take it easy for the first 48 hours. Sometimes, for your own pain relief and comfort, we may put you in a sling or a boot depending on the body part and ask you to refrain from exercise for the first 48 hours. Then, we will progress you into physical therapy. Most patients tolerate PRP very well and can be back to work in the next day or two.