The answer is, it depends. Coffee is naturally gluten-free. Having said this, it is always good to keep an eye on the ingredient list for possible contamination, including contamination from packaging. Also, make sure to buy your Instant coffee from reputable suppliers, such as your local supermarket to avoid buying counterfeit products marked as gluten-free, which may not necessarily meet this criterion. This is what Nescafe had to say when I contacted them with the question, of whether their brands of Instant Coffee are gluten-free:- “We do not have a complete list of which Nescafe products are Gluten Free. At the moment we see that Nescafè Clasico Decaf and Nescafe Clasico are in fact Gluten Free. As for the other flavors we recommend checking the label for nutrition and allergen information.”Nestle Consumer Services - US.