This is a surprisingly difficult question to answer. The obvious logic would suggest fewer wires on your desk is always desirable. But, there are some situations where a wired mouse may still be the best option. If you work in an office or room with a lot of RF interference from other devices and wireless networking hardware, a wired mouse avoids potential disconnects. Likewise, a wired mouse will never conk out on you because you forgot to charge it or didn't bring enough batteries on your extremely important business trip. While the responsiveness of wireless mice can now easily meet their wired counterparts, their convenience is, in some ways, still behind. It's up to you whether you'd prefer having to manage things like batteries and wireless reception, or if you rather just have to deal with having one more cord on your desk.