It depends. Pure Vessel, Nightmare King Grimm, and Absolute Radiance are some of the most brutal boss fights in the game. However, it still relies on the strength of the player. In my own experience, I found Nightmare King Grimm the easiest of the three once it dawned on me that the fight is like a dance where you move at the same as he does, and you try to sneak in a few hits after a successful dodge. It also helps that his attacks are telegraphed, and he doesn’t use any new moves. He only becomes faster throughout the later phases. It only took me a few tries to nail Absolute Radiance once I started treating the fight more like a platforming/obstacle challenge rather than a straightforward battle. She throws projectiles and stunts your platform with spikes, but compared to Pure Vessel, it is a more methodological encounter where you’re mostly dodging everything. After playing Celeste, I’m not sure any other platform challenge scarred me as much as that game. Meanwhile, Pure Vessel directly interacts with you and reacts to your moves too. Unfortunately, it could sometimes feel like it comes down to RNG because his attacks aren't telegraphed. For example, Lunge and Triple Slash have the same start-up animation, and it can mess up your timing if you don’t guess which one is coming at you. Pure Vessel was the most challenging fight for me due to its hectic and confusing pattern. The longer the conflict drags, it also gains new moves, which can throw you off if you’re not paying attention.