This condition, previously known as interstitial cystitis, can cause painful bladder symptoms. It affects 3 to 7% of women age 40 and older, but often goes undiagnosed. Symptoms can include discomfort, pressure, tenderness, or pain in the bladder, lower abdomen, and pelvic area. These vary from person to person, may come and go, and can chance over time. Many women also experience migraine headaches, fibromyalgia, painful intercourse, depression, or irritable bowel syndrome. The cause of painful bladder syndrome is unknown.