Yes. I bought this for a Beretta 92FS but I also have a CZ-75 Compact. I put the CZ-75 Compact in this holster to help answer this question. It definitely fits and doesn’t seem to move around. The flap can be closed with the hammer back or down in double action mode. I would not carry the weapon cocked and locked however, because there was enough of a gap that I would be worried the safety could be disengaged somehow. Otherwise, yes, the holster will accommodate the compact.