The cost of bed bug extermination depends primarily on how widespread the pest infestation is and how many rooms need to be treated. Other factors that can affect bed bug extermination costs are the amount of clutter in the location, additional furniture that needs to be treated, and construction of the home. Pest management professionals often have rates for room treatments, which can vary based on these factors. As an example, a pest management company treating a 10-by-15-foot room with light infestation might charge clients about $250, while the same size room with a heavy infestation and large amounts of clutter might cost the clients $300-$400. Clutter and heavier bed bug populations mean more product and longer labor time for the workers. Rates will vary from company to company, and from region to region, but the national average bed bug extermination cost is $320-$400. Bed bug heat treatments are an alternative way to exterminate these pests. Heat treatments are typically charged per square foot and tend to cost more than chemical or non-chemical spray solutions. Although effective, they are not usually recommended for occupied spaces, as the extreme temperatures can damage televisions, window dressings and other home furnishings.