The endocannabinoid system is a biological system composed of endocannabinoids, which are neurotransmitters produced naturally by the body, and their receptors. It plays an important role in regulating various physiological processes such as appetite, pain sensation, mood and memory. The endocannabinoid system also interacts with cannabinoids like THC to produce various effects on the body.
THC binds to cannabinoid receptors found throughout the body that make up part of the endocannabinoid system. This binding activates those receptors, triggering a range of responses within the body depending on where they’re located. For example, THC can bind to CB1 receptors found in the brain and central nervous system to cause psychoactive effects such as feelings of euphoria or relaxation. On the other hand, when THC binds to CB2 receptors found mainly in cells associated with immune functions it can reduce inflammation and even have anti-cancer properties.