Yes. The big red false morel (Gyromitra caroliniana) can be confused with the beefy false morel (Gyromitra esculenta) which contains the most toxins of all the false morel species and MUST be prepared properly if it is to be eaten. Confusing these species, and then doing an improper preparation, can have dangerous consequences. Always make sure you are 100% sure of your identification before consuming this mushroom.