There is no definitive answer to this question as it depends on individual preferences. Some people find that a vertical mouse is more comfortable to use than a traditional mouse, while others find the reverse to be true. Ultimately, it is important to try out different types of mice and see which one feels best for you. If you have any specific concerns about using a vertical mouse (such as pain in your wrist or forearm), be sure to consult with a healthcare professional before making a purchase.