Depending on how painful the broken bone is and the resources available to the clinic, your doctor may prescribe any of the following medications to relieve pain: - Acetaminophen and codeine (Tylenol #3) - Hydrocodone bitartrate and acetaminophen (Vicoden ES) - Morphine - Over-the-counter medication, such as acetaminophen (Tylenol) or ibuprofen (Advil or Motrin) - Oxycodone and acetaminophen (Percocet) Before your physician prescribes any stronger medication than OTC, they will review your medical history, including any drug allergies and medication you are currently taking, to avoid any harmful reactions to the prescribed medicine.