The average cost of living in South San Francisco is high, but it can vary depending on your lifestyle and spending habits. Here's a breakdown: Overall: The average cost of living for one person is $3,142 per month, including rent. This is 59% higher than the national average and ranks South San Francisco in the top 0.8% of the most expensive cities in the world. Without rent, the average cost of living is $919 per month. Housing: Housing is the biggest expense in South San Francisco, with an average rent of $3,017 per month. This is 146% higher than the national average. Other expenses: Utilities are 32% higher than the national average. Food costs around $677 per month for one person.