Federal drug trafficking penalties vary depending on the type of drug, the quantities trafficked, and how many offenses. For example, for first offenses: Cocaine (Schedule II) – 500-4999 grams mixture, Cocaine (Schedule II) – 5 kgs or more mixture, Fentanyl (Schedule II) – 40 – 399 grams mixture, Heroin (Schedule I) – 100 – 999 grams mixture, Methamphetamine (Schedule II) – 5 – 49 grams pure or 50 – 499 grams mixture, PCP (Schedule II) – 10 – 99 grams pure or 100 – 999 grams mixture