α-actinin is an actin-binding protein [cite]5857097[/cite] and component of the actin crosslinking functional modules; it lacks G-actin binding activity and lacks actin initiation/nucleation activity [cite]4076192[/cite]. α-actinin is an important organizer of the cytoskeleton that belongs to the spectrin superfamily (which includes spectrin, dystrophin, and related homologues)... Read More...