Understanding a cell therapy product does not end once a patient is dosed. To fully understand whether the therapeutic hypothesis is valid, it is critical to monitor the pharmacokinetics and pharmacodynamics of the drug in humans. A-DOC and A-SET teams have tools to help clients understand the distribution and function of their therapies including tracking cells in the blood and tumor, assessing changes in the tumor architecture and microenvironment based on therapy pressure, and characterizing changes in the dosed cells and tumor at the protein and genome levels.