Medications, such as Spironolactone or Metformin, have been proven to be effective for women with PCOS because it works by blocking the effects of excess androgens. Androgens are hormones that both males and females have, but males have higher levels of them. Androgens are responsible for hair growth on the face, chest, and stomach that some young women with PCOS experience. Androgens can also cause acne. However, you should ALWAYS consult your doctor before taking ANY medication.