When used at a normal dose, lidocaine drug's side effects are non-existent. However, if an excessive amount of lidocaine and prilocaine gel is used, it’s possible to experience some side effects. The most common are: - Temporary loss of sensitivity - Skin irritation and/or a burning sensation - Excessive numbness due to overuse of the delay gel To mitigate the side effects, it is advised to start by using a small dose of this gel at first, before gradually increasing the dose based on your experience and results.