Prestige Physicians also offers Xeomin, an injectable that works by relaxing facial muscle movement. Although Botox and Xeomin are both botulinum toxin A injectables, Xeomin is a “naked” injectable that doesn’t contain any supporting proteins like Botox does. Some patients develop a resistance to Botox after using it for a long period of time, and this resistance is actually tied to the supporting proteins rather than the botulinum toxin A itself. In those situations, patients can often start using Xeomin for wrinkle reduction instead.