We do not list all possible known side effects.You may experience a side effect that is not provided here. If you find that you are noticing severe side effects call your doctor or one of our pharmacists for counseling and medical advice.   Your doctor will normally balance the benefits of treatment  versus any possible  adverse reactions. Please call us and speak to the pharmacist if you have concerns about buying Biofreeze online. intense burning, stinging, redness, or irritation Increased pain, swelling, or blistering where the medicine was applied