Sazo En is the brand name of sulphasalazine which is the standard therapy for ankylosing spondylosis that do not respond to NSAIDs. It does not cause any problem in the eye.
Ankylsoing spondylosis itself involves eyes in the form of acute anterior uveitis and iritis. This problem can be managed by the use of steroids combined with mydriatic agents such as Atrisolon (Andre).