You certainly can! While small home based FFL’s have been a popular target by anti-gun politicians who try to restrict the sale of guns, home based FFL’s are more common than ever before. There is no size requirement to have an FFL, nor a requirement that you operate out of a designated commercial storefront. The ATF only cares that you are in compliance with regulations and engaged in the business of selling firearms.
You may have local restrictions about commercial activities out of your home but in nearly all cases those can be handled for small, part-time businesses. FFL123 offers personalized services and support to help small FFL businesses work with local government on zoning and licensing issues to help ensure that you can run the home based business you want.