A flare-up might linger for a week or two. However, medication can prevent HS from worsening and help you avoid the most dangerous symptoms. The goal is to get started as soon as possible. Avoiding factors that cause irritation such as hot showers and laundry machines will help keep flares at bay. If your skin starts to feel itchy or irritated, check with your doctor before using any over-the-counter medications. Some products contain alcohol which can irritate skin more easily if you're already prone to hives. While some people experience only one episode of hives every year, others suffer many more often. If you have chronic hives, talk with your doctor about what causes them and how you can best manage the condition.