Yes, Combunex 800 mg Tablet contains rifampicin, which can stain your teeth, sweat, urine, saliva, and tears for a short time (red, orange, or brown colour). This is a common but non-harmful side effect. Urine discolouration, on the other hand, could be a sign of liver disease. Consult your doctor if you experience discoloured urine, stomach pain, loss of appetite, jaundice, or yellowing of the skin or eyes.