Your doctor has many tests and procedures at their disposal to diagnose breast cancer or to learn if the cancer has spread to other parts of your body, but not all patients need all of these tests and procedures. Your doctor will select the appropriate tests based on your specific circumstances and taking into account new symptoms you may be experiencing. According to the National Cancer Comprehensive Network (NCCN) guidelines, patients with a greater than T2 tumor (>2 cm), or those with node positive disease considering pre-operative systemic therapy (chemotherapy before surgery/endocrine therapy before surgery) the following can be considered: • CBC (complete blood count) • CMP (complete metabolic panel) and liver functions and alkaline phosphatase • CT of the chest/abdomen/pelvis and bone scan • PET could be considered (optional) • MRI (optional)