Fire ant bites will often heal on their own. But if itching or swelling occurs, try the following remedies: • Apply a cold compress on the affected area (15 minutes on, 15 minutes off). • Raise the part of the body where the fire ant bit you to reduce swelling. • Use hydrocortisone cream or an antihistamine to relieve pain and itching. See a doctor right away if fire ant bites trigger symptoms of a severe allergic reaction, such as chest pain, nausea, severe sweating, loss of breath, serious swelling, slurred speech, hives, diarrhea, swelling in tongue or throat, or dizziness.