According to many research studies, it is a disease that can strike anyone of any age, colour, income, culture, or academic level. Depression is thought to be caused by genetic, biochemical, environmental, and psychological factors. Other mental diseases and ailments, such as diabetes, cancer, heart disease, and chronic pain, can also cause depression. Depression can exacerbate these issues, and vice versa. Medication for some medical conditions can sometimes create adverse effects that exacerbate depressive symptoms or lead to new onset depressive state.