When it comes to electric profiling beds, it's important to choose the right mattress to ensure comfort and safety. Generally, all types of mattresses can be used with an electric profiling bed, including memory foam, latex, and spring mattresses. However, it's crucial to ensure the mattress is compatible with the bed frame and able to adjust with the bed's movements. You'll also want to make sure the mattress is the correct size to fit the bed frame securely. Don't hesitate to consult with a medical professional or speak with the manufacturer to ensure you are choosing the best mattress for your needs.