The EasySep Human CD138 Positive Selection Kit II (Catalog# 17877) has been developed to isolate CD138+ plasma cells from mononuclear cells that have been isolated from bone marrow or blood samples via density gradient centrifugation. The EasySep Human Whole Blood and Bone Marrow CD138 Positive Selection Kit II (Catalog# 17887) has been developed to isolate CD138+ plasma cells directly from bone marrow or blood samples without prior isolation of mononuculear cells.