Absolutely Yes. In fact, many celebs and rappers have been using huge-sized pendants along with these chains. You can go for any pendant that coincides with your choice and preference. The pendant also depends on the size of the chain that you have selected. The chain size should be such that the pendant once used is not hanging too low. Too low around the stomach or too high around the neck can spoil the look and feel of it all. Use the right chain size and the right pendant. One of the most widely used Pendants is the Angel and the Cross pendants paired in one.