Original Art
I varnish all my original pieces so they can be wiped over with a damp wet cloth {no chemicals}.
I would hang your art piece out of direct sunlight to maintain it's colour.
If your art is framed then be sure to avoid spilling anything on the wood as it will stain.
Art Prints
Your print will need to be framed, and placed under glass, plexi glass or something similar. Avoid hanging in direct sunlight.