During therapy with this drug, do not use MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine). Most MAO inhibitors should also be avoided for two weeks before to and following therapy with this drug. This is important because major depression is often accompanied by anxiety or panic attacks. By reducing levels of norepinephrine and serotonin in the brain, amitriptyline may increase sensitivity to stressors which could lead to suicidal thoughts or actions. Do not use this drug if you are pregnant or may become pregnant. Do not give it to anyone under 18 years of age. It may cause birth defects or other problems if taken by women who are pregnant or think they might be pregnant. Stop taking it and call your doctor at once if you experience any symptoms such as dizziness, faintness, trouble breathing, chest pain, or heart failure. Amantriptyline is used to treat depression. It works by blocking the action of certain chemicals in the brain that cause depression. It must be taken every day for it to be effective and there are concerns about using it long-term due to its effect on the stomach. However, it may be necessary to take amitriptyline for several months to achieve complete relief from symptoms. Amitriptyline is available only through your doctor - it must be prescribed by a physician.