The basic game of Power Up Roulette is completely standard. It’s played with a French wheel and players have the usual betting options at their disposal. So likewise, there is no game strategy in the true sense of the word that applies; just a few tips and tricks to keep the game fun.
If you want, however, you can try out one of the popular roulette systems, that many players like, and see how that works for you.
Aside from that, since the straight up bets are what set this game apart, your one strategy may be to try them at least every now and then. Otherwise there’s little advantage to this game over other versions, unless you’re just joining for your viewing pleasure. That is, to play regular roulette, and enjoy the built-up thrill this variant facilitates around it.