No.
Neither the European Heating Appliance Directive 2006/119/EC nor the international directive UN ECE R122 specify replacement.
In the 1990s there was a German regulation which specified that heat exchangers had to be replaced after ten years. For Truma heaters manufactured and put into operation during this time, the replacement obligation was prolonged to 30 years. The European Heating Appliance Directive no longer specifies replacement for appliances approved after 06/2005.
The E1 mark on the type plate shows whether your heater is approved in accordance with the European Heating Appliance Directive and, consequently, was manufactured after 06/2005.