ACV might interact with medications that can decrease potassium levels, are designed to treat diabetes, or function as diuretics. There may be other interactions, so you should always check with your doctor or pharmacist. Apple cider vinegar can interact with the following medications:
Digoxin (Lanoxicaps, Lanoxin, Digox, others), insulin, glimepiride (Amaryl),glyburide (DiaBeta, Micronase, Glycron, Glynase, others), pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese, Chlorabetic 250, Dibatrol, others), glipizide (Glucotrol), tolbutamide (Orinase, Oribetic, others), chlorothiazide (Diuril, Chlorulan, others), chlorthalidone (Thalitone, Biogroton, others), furosemide (Lasix, Diaqua-2, Lo-Aqua, others), and hydrochlorothiazide (Microzide, Esidrix, others).