Yes. Dabigatran etexilate is a prodrug advisable to take orally and fully transformed by carboxylesterases to the active form dabigatran.
However, due to its low bioavailability (7%), dabigatran is given orally as dabigatran etexilate (Pradaxa). It is a lipophilic and gastrointestinally absorbed molecule that is transformed into dabigatran via two intermediates. Serine esterases are responsible for ester bond breakage.