A. The NHS suggests that you should not consume whole grapefruit or grapefruit juice with specific medications, as it may increase blood levels. Some common drugs to avoid eating with grapefruit are statins, calcium channel blockers, immunosuppressants, certain cancer drugs, and Entocort, used to treat Crohn's sickness. However, the list is not limited to these, and you must discuss them with your GP before consumption.