Women foster misery twice as regularly as men, because of different changes in hormone levels. For instance, sadness is also normal during pregnancy and menopause, just as in the wake of conceiving an offspring, enduring a premature delivery, or having a hysterectomy - these are on the whole occasions when women experience immense variances in hormones. Not only this Premenstrual condition (PMS) and premenstrual dysphoric problem (PMDD), may also cause depression.