Yes, irrigation syringe can cause dry socket. Dry socket is a serious complication that can occur after tooth extraction. It happens when the blood clot that forms in the extraction site is dislodged or dissolves, exposing the underlying bone and nerves. This can cause severe pain, and it can also delay healing. Irrigation syringes are commonly used to clean out the mouth after dental procedures, and they can sometimes inadvertently remove the blood clot from the extraction site. If you have had a tooth extracted, be sure to tell your dentist if you experience any pain or other symptoms that could indicate dry socket.