If left untreated, pharyngitis can lead to several complications. In bacterial pharyngitis, the infection can spread to other parts of the body, such as the sinuses, ears, and lungs, leading to more severe infections such as sinusitis, otitis media, and pneumonia. In some cases, untreated bacterial pharyngitis can also lead to rheumatic fever, a serious condition that can cause permanent damage to the heart and other organs. Chronic pharyngitis that is left untreated can lead to persistent throat discomfort and difficulty in swallowing. It may also increase the risk of developing other respiratory infections. Additionally, chronic pharyngitis may also increase the risk of developing certain types of throat cancer.