You can totally freeze meatloaf either before or after cooking. To freeze before cooking, place the meat mixture in a loaf pan lined with plastic wrap. Once the meatloaf mixture has been shaped in your loaf pan, wrap tightly, and then cover with foil and freeze. Defrost raw frozen meatloaf in the refrigerator for 24 hours. Bake as directed. To freeze after cooking, allow the meatloaf to cool completely. Then slice as desired. Wraps the slices individually with plastic wrap and foil. Seal well. Place all slices in an airtight container or freezer bag. Freeze up to 3 months.