The most common adverse events seen in clinical studies of RADIESSE used in the hands include bruising, redness, swelling, pain, itching, nodules or bumps/lumps, difficulty performing activities, loss of sensation and other local side effects. The most common adverse events seen in clinical studies of RADIESSE or RADIESSE (+) used in the face include bruising, redness, swelling, pain, itching and other local side effects. These are not all of the possible side effects with RADIESSE or RADIESSE (+). Merz collects information about adverse events seen with RADIESSE and RADIESSE (+) outside of clinical studies. These events are included in the RADIESSE and RADIESSE (+) Patient Information Guide based on an assessment of seriousness and potential causal relationship to RADIESSE or RADIESSE (+). Please see the Patient Information Guide available at www.radiesse.com for list of these events. Tell your health care provider about any side effects that bother you or do not go away. Important: For full safety information, please visit www.Radiesse.com or call MyMerz Solutions at 1-844-469-6379 RADIESSE and RADIESSE (+) are available by prescription only.