Ankle pain comes from a variety of sources such as sprains or twists, arthritis, the fracturing of bones, or irritation of soft tissues. Causes of ankle pain: 1. A sudden force applied to a joint can stretch it beyond its normal range of motion causing an acute injury. 2. Overuse gradually tearing down tissue until there is an injury 3. Joints lose their mobility becoming stuck in abnormal positions thus putting a strain upon the surrounding muscles and tendons leading to tightness and eventual breakdown in muscle structure. 4. Joints are in poor alignment in their normal positions causing abnormal stress on the muscles and tendons around them.