VETIVEX Hartmann's Solution for Infusion is a sterile, nonpyrogenic, isotonic crystalloid solution for fluid and electrolyte replenishment. VETIVEXHartmann's has an electrolyte profile similar to Lactated Ringer's Solution. Lactated Ringer's Solution (LRS) is a modification of Hartmann's Solution and many references discuss their clinical use and clinical effects as if they are the same, including DiBartola's textbook on fluid therapy. Hartmann'sSolution was developed in the late 1800s to deal with metabolic acidosis in pediatric humans. Alexis Hartmann, a US physician with pediatric interests from St. Louis, developed this balanced electrolyte solution by taking plain Ringer's Solution and adding lactate. Thus, Hartmann's and LRS are often referred to as being the same, since they are both balanced, isotonic electrolyte solutions that contain lactate and have an electrolyte profile similar to plasma.