There are alternative chemotherapy treatments and there are “investigational treatments.” Most investigational treatments are at major medical centers or collaborating hospitals. They are not at all standardized or proven to be safe and effective, and many of them will ultimately fall by the wayside. So, they are often a gamble. The best way to learn what is available is to call the medical oncology division at your region’s medical center and ask what clinical trials are available for patients with prostate cancer that is no longer responding to chemotherapy. My research group is trying to obtain a blood sample for DNA testing in men with advanced prostate cancer. If you or anyone you know is interested in participating, please contact me by email: wcatalona@nmff.org