Mood Balance Biotect combines the benefits of three of the most effective supplements for natural mood management: saffron, 5-HTP and SAMe. Clinical trials on each of these three natural substances suggest they promote a healthy, positive mood. Saffron, dried stigmas of the saffron flower, provide unique antioxidants: crocins, which are carotenoids, and safranal 5-HTP (5-hydroxytryptophan), produced by the body from the amino acid tryptophan, is a precursor to serotonin SAMe, (S-adenosylmethionine) produced by the body from the amino acid methionine, is involved in producing neurotransmitters in the brain Caution: If you are pregnant, nursing, on medication, or being treated for a medical condition, consult with your healthcare practitioner.