<p>The scientific name of the tall Oregon grape is Mahonia aquifolium. Some scientists prefer to call it Berberis aquifolium. The species name "aquifolium" means "spiny leaves" in Latin.<br><br> Oregon grape is safe for most people when applied directly to the skin. It can cause some side effects such as itching, burning, irritation, and allergic reactions.<br><br> <b>Directions</b><br> As a dietary supplement take 1-2 ml (approx. 28-56 drops) 3 times a day in a small amount of water or consult your doctor.</p>