Berberine HCL (HCI) (Hydrochloride) Extract is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. It is commonly found in many natural plants including barberry, goldenseal, and goldthread. Studies have shown a dose of 500 mg taken 3 times per day can help regulate blood sugar, insulin, and contribute to weight loss as well as offer other health benefits. Berberine is considered an Active PK meaning it acts as a power ampk metabolic activator. Our Berberine complex supplement is sold in 500mg capsule form. (1,500 serving size spaced out of the day as only 500mg should be taken at one time). It is manufactured within the US at a GMP Certified facility and purity testing can be provided upon request.