Berberine Synergy supplies berberine combined with alpha lipoic acid to help support cardiovascular health, and liver health.* Berberine is an alkaloid compound found in the roots, rhizomes, stems, and bark of several plants commonly used in botanical and Chinese medicine, such as goldenseal, Oregon grape, barberry, and Berberis aristata. Lipoic acid is best known for its antioxidant properties.* It is also a key cofactor for mitochondrial enzymes involved in cellular metabolism and energy (ATP) production.