Use sizing information provided prior to purchase for best fit.The Comfort Cool Wrist and Thumb CMC Restriction splint is similar to our popular Comfort Cool Thumb CMC Restriction splint but with added length and a wide wrist strap to provide additional support to the wrist. Painful conditions such as Arthritis, Carpal Tunnel, De Quervains, Repetitive Stress Injuries, Sprains and Strains to the wrist can benefit from these additional features while at the same time support and protect the thumb joint and ligaments.