Cleft lip and cleft palate repair is surgery to fix birth defects of the upper lip and palate. A cleft lip may be just a small notch in the lip and may also be a complete split in the lip that goes all the way to the base of the nose. Cleft palate is a congenital deformity that causes a multitude of problems and represents a special challenge to the medical community. Special care is needed for patients with cleft palate. In this book “Art and Science of Cleft Lip and Cleft Palate Repair”, embryology and anatomy of cleft lip and cleft palate is very interesting. There are total 14 chapters provided in this book. Various classification systems have been mentioned with clinical photographs. Unilateral cleft lip repair, bilateral cleft lip repair, cleft palate repair, cleft nose repair, operation for velopharyngeal insufficiency are described with drawings and photographs. Guidelines for anesthesia in cleft surgeries help reduce mortality and mortalities associated with cleft surgeries.