What Is MiraLAX? MiraLAX (Polyethylene Glycol 3350) is a new kind of OTC laxative. It is safe and effective* and treats occasional constipation by working with your body to restore its natural rhythm. MiraLAX is the #1 prescribed laxative–it has been the #1 choice of doctors for years–and MiraLAX is the first prescription laxative in more than 30 years to be made available OTC. Prescription Heritage For years now, MiraLAX has been prescribed most by doctors–more than any other laxative–and now it's available without a prescription. MiraLAX works with your body's natural rhythm to relieve constipation safely, without the harsh side effects of cramps or gas. In fact, MiraLAX actually reduces cramps and gas that can be caused by constipation. No wonder your doctor prefers MiraLAX. For constipation, doctors prefer MiraLAX more than any other prescription drug or OTC laxative. Doctors recommend MiraLAX more than fibers, stimulants, stool softeners or mineral oils to relieve constipation. The Most Clinically Proven Laxative Medicines can work differently for different people. To decide how to treat their patients, doctors look at the clinical research. The active ingredient in MiraLAX has been studied and proven safe and effective in more high-quality clinical trials than any other OTC laxative. In 2005, the American College of Gastroenterology (ACG) reviewed all of the clinical research in North America for OTC laxatives. MiraLAX§ is the only OTC laxative that received a "Grade A Recommendation"–their highest rating. No wonder MiraLAX is preferred most by doctors. Some OTC laxatives that you can buy today have been available for 30, 50 or even over 100 years. You might think that because they have been around for a long time, they must all work for you. But in its 2005 review, The American College of Gastroenterology concluded that there is not enough clinical research on either stimulant laxatives or