mstyslavity/prisma_v3 huggingface dataset:
Objective: This study aims to uncover the opaque decision-making process of an artificial intelligence (AI) agent for automatic treatment planning. Approach: We examined a previously developed AI agent based on the Actor-Critic with Experience Replay (ACER) network, which automatically tunes treatment planning parameters (TPPs) for inverse planning in prostate cancer intensity modulated radiotherapy. We selected multiple checkpoint ACER agents from different stages of training and applied an explainable AI (EXAI) method to analyze the attribution from dose-volume histogram (DVH) inputs to TPP-tuning decisions. We then assessed each agent's planning efficacy and efficiency and evaluated their policy and final TPP tuning spaces. Combining these analyses, we systematically examined how ACER agents generated high-quality treatment plans in response to different DVH inputs. Results: Attribution analysis revealed that ACER agents progressively learned to identify dose-violation regions from DVH inputs and promote appropriate TPP-tuning actions to mitigate them. Organ-wise similarities between DVH attributions and dose-violation reductions ranged from 0.25 to 0.5 across tested agents. Agents with stronger attribution-violation similarity required fewer tuning steps (~12-13 vs. 22), exhibited a more concentrated TPP-tuning space with lower entropy (~0.3 vs. 0.6), converged on adjusting only a few TPPs, and showed smaller discrepancies between practical and theoretical tuning steps. Putting together, these findings indicate that high-performing ACER agents can effectively identify dose violations from DVH inputs and employ a global tuning strategy to achieve high-quality treatment planning, much like skilled human planners. Significance: Better interpretability of the agent's decision-making process may enhance clinician trust and inspire new strategies for automatic treatment planning.
The interaction between humans and AI in safety-critical systems presents a unique set of challenges that remain partially addressed by existing frameworks. These challenges stem from the complex interplay of requirements for transparency, trust, and explainability, coupled with the necessity for robust and safe decision-making. A framework that holistically integrates human and AI capabilities while addressing these concerns is notably required, bridging the critical gaps in designing, deploying, and maintaining safe and effective systems. This paper proposes a holistic conceptual framework for critical infrastructures by adopting an interdisciplinary approach. It integrates traditionally distinct fields such as mathematics, decision theory, computer science, philosophy, psychology, and cognitive engineering and draws on specialized engineering domains, particularly energy, mobility, and aeronautics. Its flexibility is further demonstrated through a case study on power grid management.
Eye-movement related artifacts including blinks and saccades are significantly larger in amplitude than cortical activity as recorded by scalp electroencephalography (EEG), but are typically discarded in EEG studies focusing on cognitive mechanisms as explained by cortical source activity. Accumulating evidence however indicates that spontaneous eye blinks are not necessarily random, and can be modulated by attention and cognition beyond just physiological necessities. In this exploratory analysis we reanalyze a public EEG dataset of musicians listening to or imagining music (Bach chorales) while simultaneously reading from a sheet of music. We ask whether blink timing in reading music, accompanied by listening or imagery, is sufficient to uniquely identify the music being read from a given score. Intra-subject blink counts and timing are compared across trials using a spike train distance metric (Victor and Purpura, 1997). One-trial-left-out cross-validation is used to identify the music being read with above chance level accuracy (best subject: 56\%, chance: 25\%), where accuracy is seen to vary with subject, condition, and a tunable cost factor for time shifts. Future studies may consider incorporating eye blink contributions to brain decoding, especially in wearables where eye blinks could be easier to record than EEG given their higher amplitudes.
This paper focuses on a key challenge in visual emotion understanding: given an art image, the model pinpoints pixel regions that trigger a specific human emotion, and generates linguistic explanations for it. Despite advances in general segmentation, pixel-level emotion understanding still faces a dual challenge: first, the subjectivity of emotion limits general segmentation models like SAM to adapt to emotion-oriented segmentation tasks; and second, the abstract nature of art expression makes it hard for captioning models to balance pixel-level semantics and emotion reasoning. To solve the above problems, this paper proposes the Emotion stimuli Segmentation and Explanation Model (EmoSEM) model to endow the segmentation framework with emotion comprehension capability. First, to enable the model to perform segmentation under the guidance of emotional intent well, we introduce an emotional prompt with a learnable mask token as the conditional input for segmentation decoding. Then, we design an emotion projector to establish the association between emotion and visual features. Next, more importantly, to address emotion-visual stimuli alignment, we develop a lightweight prefix adapter, a module that fuses the learned emotional mask with the corresponding emotion into a unified representation compatible with the language model. Finally, we input the joint visual, mask, and emotional tokens into the language model and output the emotional explanations. It ensures that the generated interpretations remain semantically and emotionally coherent with the visual stimuli. Our method realizes end-to-end modeling from low-level pixel features to high-level emotion interpretation, delivering the first interpretable fine-grained framework for visual emotion analysis. Extensive experiments validate the effectiveness of our model. Code will be made publicly available.
Understanding what knowledge is implicitly encoded in deep learning models is essential for improving the interpretability of AI systems. This paper examines common methods to explain the knowledge encoded in word embeddings, which are core elements of large language models (LLMs). These methods typically involve mapping embeddings onto collections of human-interpretable semantic features, known as feature norms. Prior work assumes that accurately predicting these semantic features from the word embeddings implies that the embeddings contain the corresponding knowledge. We challenge this assumption by demonstrating that prediction accuracy alone does not reliably indicate genuine feature-based interpretability. We show that these methods can successfully predict even random information, concluding that the results are predominantly determined by an algorithmic upper bound rather than meaningful semantic representation in the word embeddings. Consequently, comparisons between datasets based solely on prediction performance do not reliably indicate which dataset is better captured by the word embeddings. Our analysis illustrates that such mappings primarily reflect geometric similarity within vector spaces rather than indicating the genuine emergence of semantic properties.
The global spread of misinformation and concerns about content trustworthiness have driven the development of automated fact-checking systems. Since false information often exploits social media dynamics such as "likes" and user networks to amplify its reach, effective solutions must go beyond content analysis to incorporate these factors. Moreover, simply labelling content as false can be ineffective or even reinforce biases such as automation and confirmation bias. This paper proposes an explainable framework that combines content, social media, and graph-based features to enhance fact-checking. It integrates a misinformation classifier with explainability techniques to deliver complete and interpretable insights supporting classification decisions. Experiments demonstrate that multimodal information improves performance over single modalities, with evaluations conducted on datasets in English, Spanish, and Portuguese. Additionally, the framework's explanations were assessed for interpretability, trustworthiness, and robustness with a novel protocol, showing that it effectively generates human-understandable justifications for its predictions.
The opaqueness of many complex machine learning algorithms is often mentioned as one of the main obstacles to the ethical development of artificial intelligence (AI). But what does it mean for an algorithm to be opaque? Highly complex algorithms such as artificial neural networks process enormous volumes of data in parallel along multiple hidden layers of interconnected nodes, rendering their inner workings epistemically inaccessible to any human being, including their designers and developers; they are "black boxes" for all their stakeholders. But opaqueness is not always the inevitable result of technical complexity. Sometimes, the way an algorithm works is intentionally hidden from view for proprietary reasons, especially in commercial automated decision systems, creating an entirely different type of opaqueness. In the first part of the chapter, we will examine these two ways of understanding opacity and the ethical implications that stem from each of them. In the second part, we explore the different explanatory methods that have been developed in computer science to overcome an AI system's technical opaqueness. As the analysis shows, explainable AI (XAI) still faces numerous challenges.
This paper offers an overview of the prospects and ethics of using AI to achieve human enhancement, and more broadly what we call intellectual augmentation (IA). After explaining the central notions of human enhancement, IA, and AI, we discuss the state of the art in terms of the main technologies for IA, with or without brain-computer interfaces. Given this picture, we discuss potential ethical problems, namely inadequate performance, safety, coercion and manipulation, privacy, cognitive liberty, authenticity, and fairness in more detail. We conclude that while there are very significant technical hurdles to real human enhancement through AI, and significant ethical problems, there are also significant benefits that may realistically be achieved in ways that are consonant with a rights-based ethics as well. We also highlight the specific concerns that apply particularly to applications of AI for "sheer" IA (more realistic in the near term), and to enhancement applications, respectively.
Hierarchical multi-agent systems (HMAS) organize collections of agents into layered structures that help manage complexity and scale. These hierarchies can simplify coordination, but they also can introduce trade-offs that are not always obvious. This paper proposes a multi-dimensional taxonomy for HMAS along five axes: control hierarchy, information flow, role and task delegation, temporal layering, and communication structure. The intent is not to prescribe a single "best" design but to provide a lens for comparing different approaches. Rather than treating these dimensions in isolation, the taxonomy is connected to concrete coordination mechanisms - from the long-standing contract-net protocol for task allocation to more recent work in hierarchical reinforcement learning. Industrial contexts illustrate the framework, including power grids and oilfield operations, where agents at production, maintenance, and supply levels coordinate to diagnose well issues or balance energy demand. These cases suggest that hierarchical structures may achieve global efficiency while preserving local autonomy, though the balance is delicate. The paper closes by identifying open challenges: making hierarchical decisions explainable to human operators, scaling to very large agent populations, and assessing whether learning-based agents such as large language models can be safely integrated into layered frameworks. This paper presents what appears to be the first taxonomy that unifies structural, temporal, and communication dimensions of hierarchical MAS into a single design framework, bridging classical coordination mechanisms with modern reinforcement learning and large language model agents.
Recent advances in Multimodal Large Language Models (MLLMs) have introduced a paradigm shift for Image Quality Assessment (IQA) from unexplainable image quality scoring to explainable IQA, demonstrating practical applications like quality control and optimization guidance. However, current explainable IQA methods not only inadequately use the same distortion criteria to evaluate both User-Generated Content (UGC) and AI-Generated Content (AIGC) images, but also lack detailed quality analysis for monitoring image quality and guiding image restoration. In this study, we establish the first large-scale Visual Distortion Assessment Instruction Tuning Dataset for UGC images, termed ViDA-UGC, which comprises 11K images with fine-grained quality grounding, detailed quality perception, and reasoning quality description data. This dataset is constructed through a distortion-oriented pipeline, which involves human subject annotation and a Chain-of-Thought (CoT) assessment framework. This framework guides GPT-4o to generate quality descriptions by identifying and analyzing UGC distortions, which helps capturing rich low-level visual features that inherently correlate with distortion patterns. Moreover, we carefully select 476 images with corresponding 6,149 question answer pairs from ViDA-UGC and invite a professional team to ensure the accuracy and quality of GPT-generated information. The selected and revised data further contribute to the first UGC distortion assessment benchmark, termed ViDA-UGC-Bench. Experimental results demonstrate the effectiveness of the ViDA-UGC and CoT framework for consistently enhancing various image quality analysis abilities across multiple base MLLMs on ViDA-UGC-Bench and Q-Bench, even surpassing GPT-4o.
Accurate assessment of neuromuscular reflexes, such as the H-reflex, plays a critical role in sports science, rehabilitation, and clinical neurology. Traditional analysis of H-reflex EMG waveforms is subject to variability and interpretation bias among clinicians and researchers, limiting reliability and standardization. To address these challenges, we propose a Fine-Tuned Vision-Language Model (VLM) Consortium and a reasoning Large-Language Model (LLM)-enabled Decision Support System for automated H-reflex waveform interpretation and diagnosis. Our approach leverages multiple VLMs, each fine-tuned on curated datasets of H-reflex EMG waveform images annotated with clinical observations, recovery timelines, and athlete metadata. These models are capable of extracting key electrophysiological features and predicting neuromuscular states, including fatigue, injury, and recovery, directly from EMG images and contextual metadata. Diagnostic outputs from the VLM consortium are aggregated using a consensus-based method and refined by a specialized reasoning LLM, which ensures robust, transparent, and explainable decision support for clinicians and sports scientists. The end-to-end platform orchestrates seamless communication between the VLM ensemble and the reasoning LLM, integrating prompt engineering strategies and automated reasoning workflows using LLM Agents. Experimental results demonstrate that this hybrid system delivers highly accurate, consistent, and interpretable H-reflex assessments, significantly advancing the automation and standardization of neuromuscular diagnostics. To our knowledge, this work represents the first integration of a fine-tuned VLM consortium with a reasoning LLM for image-based H-reflex analysis, laying the foundation for next-generation AI-assisted neuromuscular assessment and athlete monitoring platforms.
Chest X-ray imaging is crucial for diagnosing pulmonary and cardiac diseases, yet its interpretation demands extensive clinical experience and suffers from inter-observer variability. While deep learning models offer high diagnostic accuracy, their black-box nature hinders clinical adoption in high-stakes medical settings. To address this, we propose X-Ray-CoT (Chest X-Ray Chain-of-Thought), a novel framework leveraging Vision-Language Large Models (LVLMs) for intelligent chest X-ray diagnosis and interpretable report generation. X-Ray-CoT simulates human radiologists' "chain-of-thought" by first extracting multi-modal features and visual concepts, then employing an LLM-based component with a structured Chain-of-Thought prompting strategy to reason and produce detailed natural language diagnostic reports. Evaluated on the CORDA dataset, X-Ray-CoT achieves competitive quantitative performance, with a Balanced Accuracy of 80.52% and F1 score of 78.65% for disease diagnosis, slightly surpassing existing black-box models. Crucially, it uniquely generates high-quality, explainable reports, as validated by preliminary human evaluations. Our ablation studies confirm the integral role of each proposed component, highlighting the necessity of multi-modal fusion and CoT reasoning for robust and transparent medical AI. This work represents a significant step towards trustworthy and clinically actionable AI systems in medical imaging.
We introduce fCrit, a dialogue-based AI system designed to critique furniture design with a focus on explainability. Grounded in reflective learning and formal analysis, fCrit employs a multi-agent architecture informed by a structured design knowledge base. We argue that explainability in the arts should not only make AI reasoning transparent but also adapt to the ways users think and talk about their designs. We demonstrate how fCrit supports this process by tailoring explanations to users' design language and cognitive framing. This work contributes to Human-Centered Explainable AI (HCXAI) in creative practice, advancing domain-specific methods for situated, dialogic, and visually grounded AI support.
Large Language Models (LLMs) such as GPT, LLaMA, and Claude achieve remarkable performance in text generation but remain opaque in their decision-making processes, limiting trust and accountability in high-stakes applications. We present gSMILE (generative SMILE), a model-agnostic, perturbation-based framework for token-level interpretability in LLMs. Extending the SMILE methodology, gSMILE uses controlled prompt perturbations, Wasserstein distance metrics, and weighted linear surrogates to identify input tokens with the most significant impact on the output. This process enables the generation of intuitive heatmaps that visually highlight influential tokens and reasoning paths. We evaluate gSMILE across leading LLMs (OpenAI's gpt-3.5-turbo-instruct, Meta's LLaMA 3.1 Instruct Turbo, and Anthropic's Claude 2.1) using attribution fidelity, attribution consistency, attribution stability, attribution faithfulness, and attribution accuracy as metrics. Results show that gSMILE delivers reliable human-aligned attributions, with Claude 2.1 excelling in attention fidelity and GPT-3.5 achieving the highest output consistency. These findings demonstrate gSMILE's ability to balance model performance and interpretability, enabling more transparent and trustworthy AI systems.
Large Language Models (LLMs) excel in translation among other things, demonstrating competitive performance for many language pairs in zero- and few-shot settings. But unlike dedicated neural machine translation models, LLMs are not trained on any translation-related objective. What explains their remarkable translation abilities? Are these abilities grounded in "incidental bilingualism" (Briakou et al. 2023) in training data? Does instruction tuning contribute to it? Are LLMs capable of aligning and leveraging semantically identical or similar monolingual contents from different corners of the internet that are unlikely to fit in a single context window? I offer some reflections on this topic, informed by recent studies and growing user experience. My working hypothesis is that LLMs' translation abilities originate in two different types of pre-training data that may be internalized by the models in different ways. I discuss the prospects for testing the "duality" hypothesis empirically and its implications for reconceptualizing translation, human and machine, in the age of deep learning.
Major Depressive Disorder is one of the leading causes of disability worldwide, yet its diagnosis still depends largely on subjective clinical assessments. Integrating Artificial Intelligence (AI) holds promise for developing objective, scalable, and timely diagnostic tools. In this paper, we present a comprehensive survey of state-of-the-art AI methods for depression detection and diagnosis, based on a systematic review of 55 key studies. We introduce a novel hierarchical taxonomy that structures the field by primary clinical task (diagnosis vs. prediction), data modality (text, speech, neuroimaging, multimodal), and computational model class (e.g., graph neural networks, large language models, hybrid approaches). Our in-depth analysis reveals three major trends: the predominance of graph neural networks for modeling brain connectivity, the rise of large language models for linguistic and conversational data, and an emerging focus on multimodal fusion, explainability, and algorithmic fairness. Alongside methodological insights, we provide an overview of prominent public datasets and standard evaluation metrics as a practical guide for researchers. By synthesizing current advances and highlighting open challenges, this survey offers a comprehensive roadmap for future innovation in computational psychiatry.
LLMs enable qualitative coding at large scale, but assessing reliability remains challenging where human experts seldom agree. We investigate confidence-diversity calibration as a quality assessment framework for accessible coding tasks where LLMs already demonstrate strong performance but exhibit overconfidence. Analysing 5,680 coding decisions from eight state-of-the-art LLMs across ten categories, we find that mean self-confidence tracks inter-model agreement closely (Pearson r=0.82). Adding model diversity quantified as normalised Shannon entropy produces a dual signal explaining agreement almost completely (R-squared=0.979), though this high predictive power likely reflects task simplicity for current LLMs. The framework enables a three-tier workflow auto-accepting 35 percent of segments with less than 5 percent error, cutting manual effort by 65 percent. Cross-domain validation confirms transferability (kappa improvements of 0.20 to 0.78). While establishing a methodological foundation for AI judgement calibration, the true potential likely lies in more challenging scenarios where LLMs may demonstrate comparative advantages over human cognitive limitations.