Mamono Hunter Youko
English title: Devil Hunter Yohko
Japanese title: 魔物ハンター妖子
Alternative titles: Demon Hunter Youko, Mamono Hunter Yohko
Type: OVA
Source: Original
Episodes: 5
Status: Finished Airing
Aired: Dec 1, 1990 to Jul 1, 1995
Duration: 37 min per ep
Rating: R+ - Mild Nudity
Studios: Madhouse
Producers: TOHO
Licensors: ADV Films
Genres: Comedy, Fantasy, Horror, Supernatural

Yohko Mono is a regular girl making her way through high school--until she learns that she is the 108th successor to a line of warriors charged with defending the earth against demons. Eventually she must fight her ultimate battle against the demon who started it all. 

(Source: ANN)