Effects of AINurse Orientation Program on Psychological Outcomes and Length of Hospital Stay: A Randomized Controlled Trial
Trial ID: NCT07171944
Status: NOT_YET_RECRUITING
Study type: INTERVENTIONAL
Phase: NA
Start date: 2025-11-01
Completion date: 2026-11-01
Sponsor: Koç University
Conditions: Delirium; Anxiety and Depression; Intensive Care Units (ICUs); Artificial Intelligence (AI); Nurse; Critical Care; Orientation
Interventions: Structured orientation program; Human Nurse
Locations: Koç University
Countries: Turkey (Türkiye)
Enrollment: 10
Age range: 18 Years - None
Sex: ALL

Summary:
Artificial intelligence (AI), now an integral part of healthcare services and presents numerous opportunities. Customized treatment plans, clinical decision support systems, predictive analysis for disease prevention, patient engagement and education, quality improvement, and error reduction are some of these opportunities. In the context of delirium prevention, risk assessment, and treatment planning, the AI-supported system AI-AntiDelirium is designed to standardize the approach to delirium management in alignment with the PADIS guidelines. A randomized controlled trial evaluating the effectiveness of this system found that the workload of nurses decreased, facilitated early diagnosis and prevention of delirium, and recommended evidence-based and individualized delirium interventions. A systematic review concluded that AI applications did not significantly impact the length of hospital stay and emphasized the need for further research. Also, AI platforms contributed to positive results in reducing anxiety and depression in patients. Furthermore, systematic reviews have demonstrated that AI-based chatbots are effective in alleviating symptoms of depression and anxiety. However, the literature includes a limited number of patient education programs specifically designed to prevent or manage delirium through AI-based approaches. Notably, there is a lack of studies comparing the effectiveness of AI-supported educational interventions with those delivered directly by nurses.

The goal of this clinical trial is to develop a structured AINurse and Human Nurse orientation training program for intensive care unit (ICU) patients and compare the effects of these training programs on ICU patients' delirium-free days, level of anxiety and depression, and length of stay in the ICU. Hypotheses of the study:

H1: Patients who receive the structured AINurse patient orientation training program will have longer delirium-free days than patients who receive Human Nurse orientation training.

H2: Patients who receive the structured AINurse patient orientation training program will have lower levels of anxiety and depression than patients who receive the Human Nurse orientation training.

H3: Patients who receive the structured AINurse patient orientation training program will have shorter lengths of stay in the intensive care unit than patients who receive the Human Nurse orientation training.

Researchers will compare the AINurse patient orientation training program and the orientation training program provided by human nurses in terms of patients' delirium-free days, level of anxiety and depression, and length of stay in the ICU.

* Those in the intervention group will receive the AINurse orientation training program twice daily for 3 days.
* Participants in the control group will receive face-to-face structured orientation training from researchers twice daily for 3 days.
* Delirium-free day assessment, anxiety and depression will be evaluated for patients in both groups over 3 days.
* The length of stay in the intensive care unit will be monitored for patients in both groups.

Eligibility criteria:
Inclusion Criteria:

* Intensive care unit confusion assessment scale (CAM-ICU scale) score of 0-2
* Age 18 years or older
* Hospitalized in the intensive care unit for at least 24 hours
* Glasgow coma scale score of 13-14-15 points
* Richmond Agitation Sedation Scale (RASS) score between -1 and +1
* No hearing problems

Exclusion Criteria:

* Intensive care unit confusion assessment scale (CAM-ICU scale) score of 6-7
* Any psychiatric illness or impaired brain function
* Defined hearing loss
* Advanced dementia
* Younger than 18 years of age
* Richmond Agitation Sedation Scale (RASS) score outside the range of -1 to +1
* Who use sedative medication
* History of surgery or disease around the ear

Outcomes:
Delirium-free days