Pilot Randomized Controlled Trial of an Artificial Intelligence (AI)-Powered Behavioral Coaching Intervention (Laguna Health) to Promote Post-Hospital Discharge Recovery for Patients With Cancer
Trial ID: NCT06004141
Status: TERMINATED
Study type: INTERVENTIONAL
Phase: NA
Start date: 2023-08-30
Completion date: 2024-01-29
Sponsor: Massachusetts General Hospital
Collaborators: Laguna Health, Inc
Conditions: Cancer
Interventions: Laguna Health
Locations: Massachusetts General Hospital Cancer Center
Countries: United States
Enrollment: 18
Age range: 18 Years - None
Sex: ALL

Summary:
The overall goal of this study is to examine the feasibility, acceptability, and preliminary efficacy of using a behavioral coaching intervention (Laguna Health) for optimizing post-hospital discharge care in patients with cancer. Patients will be randomly assigned into one of the study groups: the behavioral coaching intervention (Laguna Health) + usual care versus usual care alone.

The Laguna Health intervention has several components:

1. Post-Discharge Recovery Coaching with a Laguna Health recovery coach to help patients identify barriers to post-discharge recovery
2. Digital psycho-educational content tailored to the needs of patients with cancer
3. Personal healthcare summaries
4. Digital content and coaching on behavioral strategies to promote self-efficacy

Eligibility criteria:
Inclusion Criteria (Patients):

* Adult patients (age \> 18 years)
* Patients with cancer being treated with curative intent per chemotherapy order entry, treatment intent designation and or trial consent forms OR based on documentation in the oncology clinic notes.
* Patients with cancer being treated with palliative intent (per chemotherapy order entry, treatment intent designation and or trial consent forms OR based on documentation in the oncology clinic notes for those not receiving chemotherapy) who are experiencing their first or second hospitalization for cancer related care or complications.
* Unplanned or non-elective hospitalization at Massachusetts General Hospital (MGH)
* Planned discharge to a home environment.
* Receiving outpatient care at the MGH Cancer Center
* Access to a smartphone capable of accessing Laguna Health's app on Android or iOS
* Ability to comprehend, read, and respond to questions in English.

Exclusion Criteria (Patients):

* Patients with metastatic or advanced cancer experiencing their third or later hospitalization for cancer related care or complications as these patients likely have advanced disease and require more end-of-life care interventions.
* Patients with planned discharge to hospice or care facility other than home.
* Patients with acute or unstable psychiatric or cognitive conditions which the treating clinicians believes prohibits informed consent or compliance with study procedures

Caregiver Eligibility

* Adult (\> 18 years) relative or friend of a patient who agrees to participate in the study whom the patient identified as living with them or having in-person contact with them at least twice per week.
* Ability to comprehend, read, and respond to questions in English as Laguna Health is only available in English in this proof-of-concept study.
* Access to a smartphone capable of accessing Laguna Health's app on Android or iOS

Note that patients can enroll without an eligible caregiver.

Outcomes:
Feasibility of Laguna Health based on enrollment and intervention use rates