mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
An overview of reclaimed water reuse in China

China is facing severe water problems including scarcity and pollution which are now becoming key factors restricting developments. Creating an alternative water resource and reducing effluent discharges, water reuse has been recognized as an integral part of water and wastewater management scheme in China. The government has launched nationwide efforts to optimize the benefits of utilizing reclaimed water. This article reviewed the water reuse activities in China, including: (1) application history and current status; (2) potentials of reclaimed water reuse; (3) laws, policies and regulations governing reclaimed water reuse; (4) risks associated with reclaimed water reuse; (5) issues in reclaimed water reuse. Reclaimed water in Beijing and Tianjin were given as examples. Suggestions for improving the efficiencies of reusing urban wastewater were advanced. Being the largest user of reclaimed wastewater in the world, China's experience can benefit the development of water reuse in other regions.
Historical trends of heavy metal contamination and their sources in lacustrine sediment from Xijiu Lake, Taihu Lake Catchment, China

Concentrations of Cd, Cr, Cu, Pb, Zn and Hg in Xijiu Lake sediment from the Taihu Lake catchment, China, were analyzed. Their contamination state was investigated based on the geoaccumulation index and enrichment factors. Statistical analysis was used to differentiate the anthropogenic versus natural sources of heavy metals (HMs), and the anthropogenic accumulation fluxes were calculated to quantify anthropogenic contribution to HMs. The results indicated that the lake sediment had been heavily contaminated by Cd, enrichment of Zn and Hg was at a relatively high level, while that of Cu and Pb was in the lower-to-moderate level and Cr was in the low enrichment level. Sources of Cr in the sediment were mainly from natural inputs, while other metals, especially Cd, were predominantly derived from anthropogenic sources. In the past century, anthropogenic accumulation fluxes of Pb, Zn and Hg increased by 0.1-47.3 mg/(cm~2.yr), 2.4-398.1 mg/(cm~2.yr), and 3.7-110.3 ng/(m~2.yr), respectively, accounting for most inputs of HMs entering the sediment. The contamination state of HMs varied with industrial development of the catchment, which demonstrated that contamination started in the early 20th century, reached the maximal level between the mid-1970s and mid-1990s, and decreased a little after the implementation of constraints on high contamination industries, although the contamination of some HMs, such as Cd, Zn and Hg, is still at high levels.
Photoproducts of tetracycline and oxytetracycline involving self-sensitized oxidation in aqueous solutions: Effects of Ca~(2+) and Mg~(2+)

Tetracyclines constitute one of the most important antibiotic families and represent a classic example of phototoxicity. The photoproducts of tetracyclines and their parent compounds have potentially adverse effects on natural ecosystem. In this study, the self-sensitized oxidation products of tetracycline (TC) and oxytetracycline (OTC) were determined and the effects of Ca~(2+) and Mg~(2+) on self-sensitized degradation were investigated. The Ca~(2+) and Mg~(2+) in the natural water sample accounted for enhancement (pH 7.3) and inhibition (pH 9.0) of photodegradation of TC and OTC due to the formation of metal-ions complexes. The formation of Mg~(2+) complexes was unfavorable for the photodegradation of the tetracyclines at both pH values. In contrast, the Ca~(2+) complexes facilitated the attack of singlet oxygen (~1O_2) arising from self-sensitization at pH 7.3 and enhanced TC photodegradation. For the first time, self-sensitized oxidation products of TC and OTC were verified by quenching experiments and detected by LC/ESI-DAD-MS. The products had a nominal mass 14 Da higher than the parent drugs (designated M+14), which resulted from the ~1O_2 attack of the dimethylamino group on the C-4 atom of the tetracyclines. The presence of Ca~(2+) and Mg~(2+) also affected the generation of M+14 due to the formation of metal-ions complexes with TC and OTC. The findings suggest that the metal-ion complexation has significant impact on the self-sensitized oxidation processes and the photoproducts of tetracyclines.
原发性精索平滑肌肉瘤一例报告

讨论　平滑肌肉瘤是由具有明确平滑肌特点的细胞构成的恶性肿瘤，常发生于中老年。最常见的发病部位是腹膜后，还可以发生于大血管，以下腔静脉和下肢大静脉常见，罕见于动脉；精索平滑肌肉瘤罕见，陈春光和岑和复习1996年前国内文献共报道3例，1996年至今国内文献报道原发于精索的平滑肌肉瘤共4例，其中1例为复发转移，3例为原发。平滑肌肉瘤一般临床表现为无痛性肿块，生长相对缓慢；影像学检查表现为非特异性软组织肿物，易与其他类型间叶组织源性肿瘤相混淆。如果肿瘤细胞具有明显异形性和细胞核分裂象，术中快速病理往往倾向于梭形细胞恶性肿瘤，主要依靠病理和免疫组织化学染色检查确诊。平滑肌肉瘤应与良性平滑肌瘤和恶性如滑膜肉瘤、血管肉瘤、胃肠道间质肉瘤等其他梭形细胞肿瘤鉴别，典型的组织学结构、细胞学特点及辅助免疫组织化学可以鉴别。Desmin、H-caldesmon、SMA不具有特异性，但多项指标阳性更支持该诊断。治疗通常以手术切除为主的综合治疗为首选，放疗对预防复发和转移有一定效果~。平滑肌肉瘤可发生局部复发和远处转移，肿瘤部位和大小是重要的预后因素。
根治性膀胱切除手术预后评价的研究进展

随着膀胱癌异质性研究的不断深 入，TNM分期系统对预后的评价作用受 到人们重视。对于当前预后评价系统， 病理组织学、数据分类图、分子生物学方 面的研究均取得一定进展，现综述如下。
含服阿仑膦酸钠致创伤性溃疡三例并文献复习

骨质疏松(osteoporosis )是一种以骨量降低和骨组织微结构破坏为特征，导致骨脆性增加和易于骨折的代谢性骨病；临床表现以弥漫性骨痛、骨折为主~([1,2])．阿仑膦酸钠能明显缓解骨质疏松性骨痛，显著提高骨密度，增加骨强度，有效降低骨折风险，已成为临床抗骨质疏松治疗的一线用药．然而，不正确 的含服方法使其不良反应增加．本研究组先后接诊3例因骨 质疏松含服阿仑膦酸钠片后，发生口腔黏膜病变，且均符合创 伤性溃疡诊断标准~([3])．为了引起临床足够重视，现报告如下．
环状弹性纤维溶解性巨细胞肉芽肿1例

患者男，45岁。因颈部、上胸部、右前臂及右手背起丘疹、斑块4年余于2009年10月18日来我科就诊。患者于4年前不明原因颈项部起一黄豆大的丘疹，无痛痒，未引起重视。皮损渐向四周缓慢扩展，同时中央消退，形成环形边缘。到多家医院就诊，诊断不详，曾外用多种药物，效果欠佳。后用肤疾宁贴膏，皮损可部分消退，停用后又复发。2007年，胸部出现类似皮损，2009年4月右前臂和右手背亦出现类似皮损。既往体健，无糖尿病病史及家族遗传病史。
发疹性黄瘤并发高脂蛋白血症V型1例

患者男，35岁。因躯干和双上肢皮疹伴轻度瘙痒4年，加重1年于2009年2月8日来我科就诊。患者平素喜好甜食及酗酒，否认患有病毒性肝炎、糖尿病及其他内脏疾病和长期用药史。患者父母及其家族成员无类似疾患。
The Secondary Structure of Heated Whey Protein and Its Hydrolysates Antigenicity

Fourier transform infrared spectroscopy (FTIR) and circular dichroism (CD) were used to investigate the conformational changes of heated whey protein (WP) and the corresponding changes in the hydrolysates immunoreactivity were determined by competitive enzyme-linked immunosorbent assay (ELISA). Results showed that the contents of α- helix and β-sheet of WP did not decrease much under mild heating conditions and the antigenicity was relatively high; when the heating intensity increased (70 ℃ for 25 min or 75 ℃ for 20 min), the content of α- helix and β-sheet decreased to the minimum, so was the antigenicity; However, when the WP was heated at even higher temperature and for a longer time, the β-sheet associated with protein aggregation begun to increase and the antigenicity increased correspondingly. It was concluded that the conformations of heated WP and the antigenicity of its hydrolysates are related and the optimum structure for decreasing the hydrolysates antigeniity is the least content of α-helix and β-sheet. Establishing the relationship between the WP secondary structure and WP hydrolysates antigenicity is significant to supply the reference for antigenicity reduction by enzymolysis.
阿德福韦酯致Fanconi综合征一例

患者男，48岁。因“全身骨痛1年，加重伴行走困难 1个月”于2010年7月28日人院。患者患慢性乙型肝炎 20余年，口服阿德福韦酯10 mg/d达5年。入院体检：T 36.5℃, P 78次/min，呼吸平稳，BP 120/70 mm Hg (1 mm Hg = 0.133 kPa)。血生化：肌酐 107 μmol/L, GFR 70 ml?min~(-1)?1.73 m~(-2)，血钙 2.22 mmol/L，磷 0.46 ~ 0.50 mmol/L，碱性磷酸酶 179 IU/L,25-羟维生素 D_3 12.97 ng/ml，血糖正常。尿生化：尿糖3 +,24h尿磷27 mmol，尿白蛋白 89.9 mg/L,β_2微球蛋白75.6 mg/L。尿氨基酸检测示尿中乳酸和数种氨基酸（丙氨酸、甘氨酸、丝氨酸、苏氨酸、聚谷氨酸）增高，并检出葡萄糖和丝氨酸/苏氨酸倒置，未见其他异常代谢产物。正电子发射计算机体层成像CT(PET-CT)：全身骨骼氟脱氧葡萄糖(FDG)代谢欠均匀，未见明显异常增高灶。全身骨核素显像提示全身弥漫性骨代谢异常（图1）。骨髓穿刺：骨髓增生减低，粒、红二系相对增生活跃，巨核细胞增生活跃，血小板聚集分布。骨密度：脊椎、髋部骨质疏松。肾穿刺：肾小管弥漫性颗粒变性伴多灶性萎缩，偶见蛋白管型形成，间质多灶性纤维化伴小灶钙化，小灶性淋巴细胞浸润，间质血管（-）。免疫荧光：IgA -、IgG ±、IgM -、 C_3 ±、C_4 -、C_(1q) -。免疫组化：HBsAg(-)（图2）。血HBV pre-S1 (+)、HBsAg定量>250 × 10~3 IU/L、抗-HBs 0.12 × 10~3 IU/L/HBeAg 44.11 × 10~3 IU/L、抗-HBe 4.22 × 10~3 IU/L、抗-HBc 6.94 × 10~3 IU/L. HBV 核酸检测：< 1 × 10~6拷贝/L。入院后考虑阿德福韦酯有导致肾功能损害的报道，故停用阿德福韦酯，并补充中性磷30 ~ 45 ml/d，维生素D钙咀嚼剂600 mg/d，骨化三醇胶丸50 ~ 100 μg/d.3个月后复查血磷升至1.05 mmol/L，骨痛缓解，6个月后血磷1.12 mmol/L，骨痛消失。
南方红壤侵蚀区典型流域土壤侵蚀危险性评价

土壤侵蚀危险性可对土壤侵蚀发生的可能性、程度和侵蚀发展进行估测评价~([1]) ，对保护土壤资源、农业开发及经济建设具有预防预警的重大意义~([2]) 。对此不少学者已开展了相关研究，取得了一定成果~([3]) 。目前，土壤侵蚀危险性的评价方法主要有两种：土壤抗蚀年限法和土壤侵蚀因子权重评分法~([4]) 。近十几年来，随着3S技术的应用，土壤侵蚀因子权重评分法的相关研究日益受到重视~([4]) 。 我国南方红壤地区总面积203。5万km~2 ，占全国土地总面积的21%，水土流失面积达60余万km~2 ，是南方面积最大、垦殖指数最高、水土流失最为严重的区域~([5]) 。建立适合于区域的土壤侵蚀危险性评价模型对土壤侵蚀危险性进行定量评价是土壤侵蚀防治的关键之一。因此，研究南方红壤侵蚀区的土壤侵蚀危险性评价模型，对于生态环境的恢复与重建具有重要的意义~([6]) 。本研究以南方红壤侵蚀区的典型代表朱溪河小流域为研究对象，采用土壤侵蚀因子权重评分法，提出了土壤侵蚀危险性评价的可行性模型，揭示其空间分布特征，以期为类似区域在水土保持、生态恢复等方面提供借鉴。
两种氨挥发测定方法的比较研究

氨（NH_3 ）是空气中重要的碱性气体，对于中和大气中的酸性物质和大气环境有重要影响。目前全球每年大约有9。3×10~6 mol NH_3 进入大气层，并呈不断增加的趋势~([1]) ，大气中NH_3 浓度升高将导致沉降至地表的活性氮增多，从而引发诸如水体富营养化、土壤酸化等一系列的生态环境问题~([2]) 。农业活动如施肥和养殖业中畜禽粪便等会造成大量的NH_3 挥发~([3]) ，自1980年以来，由农业生产引起的NH_3 排放已成为大气NH_3 的主要来源之一~([4]) 。欧洲80%～95%的氨排放来自农业生产活动~([5]) ，在加拿大NH_3 挥发的绝大部分来自畜牧业~([6]) 。中国1990年由农田排放的NH_3 为1。80 Tg N，占施肥的11%，1995年增至2。7 Tg N~([7]) 。由于农业生产过程中排放的NH_3 量十分巨大，因此关于农田NH_3 挥发的研究一直是农田生态系统氮循环的一个重要内容。
基于可见光-近红外漫反射光谱的红壤有机质预测及其最优波段选择

有机质是土壤肥力、土壤质量的重要指标，同时也是土壤碳库的重要组成部分。传统的土壤有机质测试方法费时、繁琐，难以满足快速监测土壤有机质含量的需求。近年来，具有无损、快速、简便等优点的可见-近红外光谱技术的应用为土壤有机质的快速监测提供了有效途径。
手术治疗着色性干皮病伴发的皮肤鳞状细胞癌和基底细胞癌一例

患者女，30岁，2009年11月2日因面颈、 胸背及前臂灰褐色斑丘疹20余年，面部多处肿物10余年来我院就诊。患者7岁时，面部出现散在灰褐色斑点，随年龄增长皮损增多,逐渐扩展至胸背和前臂。12岁时，面部出现肿物， 逐渐增大增多并伴有破溃。2006年于外院诊断为着色性干皮病，上唇肿物病理诊断为基底细胞癌,行面部肿物切除术、二氧化碳激光烧灼术及上唇基底细胞癌放射治疗。治疗后上唇癌肿消失，而皮肤及软组织出现萎缩，导致唇系带外露，唇闭合不全。家族史：患者系足月顺产,否认父母近亲结婚。其弟面颈及前臂亦有相同灰褐色斑点，2007年曾行面部肿物切除，术后病理诊断为基底细胞癌， 鳞状细胞癌。其余家庭成员未见此病。
色素失禁症并心肌致密化不全一例

患儿女，4岁，因心率增快7 d，呼吸困难、皮肤青紫 40 min 入院。追问病史,患儿出生后不久即出现全身红色斑丘疹，随后皮疹处出现黄色水疱，破溃后留有灰褐色色素斑， 呈条状，下肢皮肤留有瘢痕。患儿于入院前 7 d 被发现心前区搏动增强增快，无前驱感染病史及药物、毒物接触史。于当地医院诊断为病毒性心肌炎，给予静脉滴注利巴韦林、头孢哌酮舒巴坦钠，在滴注头孢哌酮舒巴坦钠过程中患儿出现呼吸 困难，口周发青，四肢厥冷，诊断为过敏性休克,抢救后转入我院儿童重病监护病房。体检：体温36.1℃，心率164次，呼吸 45 次，血压 80/45 mm Hg(1 mm Hg = 0.133 kPa)。 神志清醒，精神差。生长发育较同龄儿落后，智力无异常。颜面、口唇、四肢发绀，四肢凉,毛细血管再充盈时间5 s。股动脉搏动弱,未触及挠动脉及足背动脉搏动。毛发稀黄，躯干、四肢可见不规则黑褐色色素沉着斑，呈条纹状、泼溅状和漩涡状(图1);双下肢皮肤散在瘢痕。牙齿萌出不全，牙齿形态异常， 呈圆锥状(图2);指甲未见异常。双肺底可闻及细小水泡音。 心尖搏动弥散，心音低钝，未闻及杂音。腹部略胀，肝脏肋下触及3.5 cm,质韧。辅助检查:X线胸片：心影增大,肺淤血改变。心脏彩超示：心内膜及心内膜下心肌增厚，呈不规则小梁状或窦隙状（图3)，窦隙内显示与心腔相通的血流信号(图 4)。全心扩大，左心室壁可见致密化不全；心功能减退，左室射血分数为27%；左心室舒张期呈限制性充盈；轻度肺动脉高压；肝脏增大淤血。心电图示：窦性心动过速，室性早搏， ST-T异常(STV1-V4形态弓背抬高，STⅡ、Ⅲ、avF、V5、V6下移），右心房肥大。磁共振示：颅脑平扫未见异常。眼科检查未见异常。入院后给予抗休克、强心利尿、纠正心衰治疗，治疗 11 d,复查心脏彩超，左室射血分数为35%，病情稳定带药出院。患儿系足月顺产，其父身体健康，患儿母亲皮肤有少量色素沉着。其母亲否认家族遗传病史,患儿家属拒绝活检及基因学检查。出院诊断：心源性休克、心力衰竭、心肌致密化不 全、色素失禁症。
诱导性多能干细胞在缺血性心脏病中的研究进展

缺血性心脏病已成为人类死亡的主要原因，特别是冠心 病急性心肌梗死后，因大量终末分化的心肌细胞坏死后再生 能力有限，使心功能严重下降，引发左室重构和扩大，并最终 导致心力衰竭，预后很差．现有冠脉再通治疗（包括急诊溶 栓和介入）虽能挽救部分缺血心肌，但本身不能实现心肌再 生．近年来，采用干细胞移植的方法进行心肌重建应运而 生，为缺血性心脏病的治疗开辟了新的途径．诱导性多能干 细胞（iPSC）有胚胎样干细胞的特性且为自体来源，作为移植 的供体细胞，能够在体内分化为心肌细胞，而使其再次成为 心血管再生领域的研究热点，并显示良好的临床应用前景．
子宫内膜小细胞癌一例

讨论　子宫内膜小细胞癌属于神经内分泌肿瘤，临床表 现中异常阴道出血占首位，其次为腹部包块、腹部疼痛等． 有时炎症和肿瘤的症状相互掩盖，因此绝经后妇女盆腔炎 症，需要考虑恶性肿瘤可能．子宫内膜小细胞癌常伴有癌旁 综合征，如引起眼的视觉障碍或肾的膜性肾小球肾炎等．本例主要表现为阴道不规则流血．子宫内膜小细胞癌侵袭性很强，易发生盆腔主动脉旁淋巴结及远处转移，就诊时多已发生远处转移，预后极差，此例有宫颈管转移,卵巢及盆腔淋巴结尚无转移．子宫内膜小细胞癌病理特征：子宫内膜小细胞癌的病理组织学特征为癌细胞形态一致，为小圆形或卵圆形，呈条索状或巢状分布，胞质少，核较大，核仁不明显，核分 裂象多见，由于核的折叠可呈现出嵌合体．免疫组化NSE 及Syn呈阳性．子宫深肌层浸润及脉管瘤栓很易发现，而在本病例中也同样可见．子宫内膜小细胞癌能高频表达NSE， 阳性率约79%， Syn、CgA的阳性率分别约42%、38%．CgA表达阳性率的差异，有助于判断妇科小细胞癌的起源部位．本例肿瘤表现出阳性反应仅有Syn+，未检测到嗜铬粒蛋白 A．子宫内膜小细胞癌的诊断标准：（1）有明确的原发子宫内膜起源；（2）可见小到中型细胞的片层状生长，可或不合并其他肿瘤亚型成分；（3）免疫组化检测至少有1种神经内分泌标志物阳性．本例具备上述典型特征．子宫内膜小细胞癌应采取以手术为主的综合治疗，广泛手术切除术后辅助放疗、化疗及内分泌治疗．
非小细胞肺癌个体化治疗中相关分子标志物的研究进展

随着分子生物学检测技术的进步和靶向基因研究的深 入，人们不但能从肿瘤组织中提取DNA进行基因检测，还能 从外周血中捕获循环肿瘤细胞以获得目的基因的突变信 息~([28])．个体化治疗的发展离不开靶向基因的检测，随着 ERCC1、RRM1、BRCA1、TS等更多靶基因检测技术标准化的 建立，NSCLC的治疗效果将得到大大改善．
核电站工作人员外周血淋巴细胞染色体畸变分析

人外周血淋巴细胞染色体畸变分析作为“生物剂量计” 估算核辐射事故受照人员的剂量，已得到广泛地应用，同时 也是评价辐射远后效应的重要指标．国内在有关慢性低剂 量受照人员，特别是放射工作人员染色体畸变分析方面已积 累了大量的资料~([1-3])．但是，国内有关核电站工作人员外周 血淋巴细胞染色体畸变分析报道极少．为此，本研究对国内 某核电站个人年有效剂量和从业期间累积有效剂量（以下 简称累积有效剂量）资料较为完整的188名工作人员进行了 外周血淋巴细胞染色体畸变随访观察，以分析染色体畸变与 工作人员年有效剂量和累积有效剂量的关系．
辐射诱导放射抗拒鳞癌细胞株的蛋白质组学差异分析

放射抗拒是肿瘤放射治疗失败的重要原因之一，寻找放射增敏靶点和放射敏感性预测因子具有重要意义．本实验室成功建立辐射诱导放射抗拒株的人喉鳞癌细胞株(Hep-2R)，以基因芯片初步分析出放射抗拒株基因表达谱的改变~([1])，并证实了在Hep-2R中高表达的人端粒保护蛋白之一的蛋白质hPOTI对放射敏感性的影响~([2])．基因芯片技术虽然能够反映基因表达的相关信息，但并不能够完全准确反映蛋白质合成的情况．本研究立足于蛋白质实际表达水平，运用双向电泳和质谱分析寻找与放射敏感性相关的蛋白质，为研究新的放射增敏靶点奠定基础．
Transcriptional changes in epigenetic modifiers associated with gene silencing in the intestine of the sea cucumber, Apostichopus japonicus (Selenka), during aestivation

The sea cucumber, Apostichopus japonicus, undergoes aestivation to improve survival during periods of high-temperature. During aestivation, the metabolic rate is depressed to reduce the consumption of reserved energy. We evaluated the role of epigenetic modification on global gene silencing during metabolic rate depression in the sea cucumber. We compared the expression of epigenetic modifiers in active and aestivating sea cucumbers. The expression of three genes involved in DNA methylation and chromatin remodeling (DNA (cytosine-5)-methyltransferase 1, Methyl-CpG-binding domain protein 2), and Chromodomain-helicase-DNA-binding protein 5) was significantly higher during aestivation (Days 20 and 40). Similarly, we observed an increase in the expression of genes involved in histone acetylation (Histone deacetylase 3) and Histone-binding protein RBBP4) during the early (Days 5 and 10) and late phases (Days 20 and 40) of aestivation. There was no change in the expression of KAT2B, a histone acetyltransferase. However, the expression of histone methylation associated modifiers (Histone-arginine methyltransferase CARMER and Histone-lysine N-methyltransferase MLL5) was significantly higher after 5 d in the aestivating group. The results suggest that the expression of epigenetic modifiers involved in DNA methylation, chromatin remodeling, histone acetylation, and histone methylation is upregulated during aestivation. We hypothesize that these changes regulate global gene silencing during aestivation in A. japonicus.
肌电生物反馈疗法治疗脑卒中早期患者上肢功能障碍

目的探讨肌电生物反馈疗法治疗脑卒中早期患者上肢功能障碍的有效性。方法将发病 <3个月的脑卒中患者23例分为肌电生物反馈组13例和常规组10例，~2组均给予常规康复治疗，肌电生物反馈组在此基础上增加肌电生物反馈疗法。治疗前及治疗1个月后评估2组患者偏瘫侧腕背伸肌肌力、腕关节主动活动度（AROM)、腕背伸平均肌电值（AEMG)/Fugl-Mey_er运动功能评分（FMA)上肢部分、功能独立性测量量表（FIM)自理活动部分。结果经过1个月的治疗，肌电生物反馈组AROM/AEMG/FMA/FIM评分较治疗前明显升高，差异有统计学意义（P<0.05)，组间比较差异有统计学意义（P<0.05)。结论肌电生物反馈疗法结合常规康复治疗能明显改善脑卒中早期患者的上肢功能。
Symmetries and Exact Solutions of the Breaking Soliton Equation

With the aid of the classical Lie group method and nonclassical Lie group method, we derive the classical Lie point symmetry and the nonclassical Lie point symmetry of (2+1)-dimensional breaking soliton (BS) equation. Using the symmetries, we find six classical similarity reductions and two nonclassical similarity reductions of the BS equation. Varieties of exact solutions of the BS equation are obtained by solving the reduced equations.
促红细胞生成素治疗肿瘤相关性贫血的应用

肿瘤相关性贫血(cancer related anemia, CRA)是肿瘤本身或肿瘤相关治疗（主要是放、化疗）引起的一种常见临床症状，是恶性肿瘤常见的伴随疾病之一，对肿瘤患者的治疗依从性、疗效、预后及生活质量等方面均有较大影响。因此，对于CRA的治疗越来越受到临床医生的关注。
弥散加权成像与PET-CT对鼻咽癌诊断效力的比较研究

鼻咽癌是华南地区的常见肿瘤．目前主要通过鼻咽部 的磁共振检查、胸片、腹部超声及全身放射性骨扫描对鼻咽 癌患者进行治疗前分期及治疗后随访．弥散加权成像 （DWI）技术可以一次性全身大范围扫描，而且安全、无辐射， 更无需造影剂．我们对43例鼻咽癌患者行全身DWI和 PET-CT检查，并比较二者诊断鼻咽癌原发灶和转移灶的效 力，以探讨DWI在鼻咽癌诊断中的价值．
双带线锚钉治疗髌腱断裂

目的探索双带线锚钉治疗髌腱断裂的方法及临床疗效。方法采用两枚带线锚钉治疗髌腱断裂患者7例，其中急性断裂5例，陈旧断裂2例。结果7例患者随访19～48个月，平均27个月，术后评价参照Lysholm评分标准：优7例。结论采用两枚带线锚钉治疗髌腱断裂，具有方法简单，修复可靠，可早期行走及康复训练等优点。
经纤维支气管镜肺活检结合盲刷检对周围性肺癌的诊断价值

目的 探讨经纤维支气管镜（纤支镜）肺活检结合盲刷检对周围性肺癌的诊断价值。 方法选择肺周围性病变患者202例，常规行经纤支镜肺活检结合盲刷检；其中经纤支镜、CT引导下经皮肺活检或开胸确诊周围性肺癌66例，对确诊的66例患者进行回顾性分析。 结果66例中，经纤支镜肺活检结合盲刷检确诊肺癌19例（28.79%），其中腺癌15例，鳞癌3例，小细胞肺癌1例 。19例中，纤支镜下未见异常6例（9.09%）；纤支镜下见黏膜充血、管腔变形者13例（19.70%）；全部病例未发生严重并发症。 结论纤支镜下肺活检结合盲刷检是诊断周围性肺癌安全、有效的方法。
ANALYSIS OF FDTD TO UPML FOR MAXWELL EQUATIONS IN POLAR COORDINATES

An FDTD system associated with uniaxial perfectly matched layer (UPML) for an electromagnetic scattering problem in two-dimensional space in polar coordinates is considered. Particularly the FDTD system of an initial-boundary value problems of the transverse magnetic (TM) mode to Maxwell's equations is obtained by Yee's algorithm, and the open domain of the scattering problem is truncated by a circle with a UPML. Besides, an artificial boundary condition is imposed on the outer boundary of the UPML. Afterwards, stability of the FDTD system on the truncated domain is established through energy estimates by the Gronwall inequality. Numerical experiments are designed to approve the theoretical analysis.
腹腔镜肝中叶切除术

腹腔镜肝切除术由于其显著的微创优势已作为肝切除 术的另一种选择应用于临床~([1])，但腹腔镜肝中叶切除术 （laparoscopic central hepatectomy，LCH）文献报道少见．我 们实施腹腔镜肝中叶切除术治疗肝肿瘤3例，现总结如下．
Ilizarov外固定架在断指再植术后指体延长中的应用

手指离断是临床常见的严重外伤，常合并骨折、脱位、神经血管的损伤。因为伤情造成骨缺损，加上术中短缩部分指体，术后均出现一定程度的手指短缩。2007年6月至2009年12月，我院对48例断指再植成功合并指体短缩的患者应用Ilizaxov技术进行指延长，取得了满意的疗效。
茶园土壤重金属安全性评价研究进展

土壤是植物赖以生存的重要物质基础，土壤的安全性是影响食品安全性的直接因素。随着国内外茶叶市场对茶产品的食用安全和卫生问题关注度的不断增强，人们对无公害茶、绿色食品茶和有机茶等产品的需求也越来越高。解决茶叶污染问题、提高茶叶产品质量必须从源头有效控制茶园土壤环境和质量。因此，对茶园土壤重金属的研究进展进行总结，以期为茶叶的安全生产提供参考。
广东油茶品种资源现状及育种方向

广东是我国油茶原产中心之一，油茶品种资源丰富，其栽培利用已有2300多年的历史。油茶地方品种资源在粤北、粤西、粤东18个县（市）均有分布，油茶种类有红花、白花、黄花三个类型。树型包括乔木型、小乔木型和灌木型；叶形有大叶和中小叶；果型有特大果型、大果型、中果型和小果型。我省较著名的油茶品种有高州大果油茶、广宁红花油茶、大白山茶、窄叶短柱茶、香花糙果茶等10多个品种类型。生产栽培以有性品种为主，约占90%，引进品种主要有广西软枝油茶、湖南油茶和江西油茶等。目前广东油茶栽培面积仅10万hm~2，年产茶籽3万t，占全国总产的3%，居全国第6位。制约因素主要是优良品种和丰产栽培技术的匮乏。挖掘地方优势品种资源和引进选育高产、高油、高抗油茶良种并普及无性系品种是广东油茶品种选育和生产发展的方向。
特效植物营养素喷施时期对迟菜心产量的影响

在迟菜心生长不同时期用特效植物营养素(SPNE)喷施植株，比较了不同时期喷施SPNE的植株与对照植株的生物产量、商品产量。结果表明，用SPNE喷施1次的植株的生物产量、商品产量均超过用清水喷施的对照；在移栽10 d后喷施1次SPNE植株增产幅度最高，在秧苗期喷施1次SPNE的植株比移栽76 d才喷施1次SPNE的增产幅度高，在不同时期喷施SPNE对迟菜心产量的影响不同。
2011年上半年广东花卉产业发展形势与对策建议

2011年上半年，广东花卉产业发展形势严峻，出现由于花卉价格剧烈波动而导致的花卉保护地面积大幅下降等新形 势，花卉产业整体开始向高端市场转型．但仍存在花卉品种培育结构不合理、花卉市场价格缺乏稳定机制、花卉科技研发主体培育 不足、花卉集散缺乏专业物流等问题．需要采取加快广东本地特色花卉和传统花卉育种、加大政策投人力度以稳定市场、积极引导 和培育消费市场、构建专业花卉物流体系等措施，以促进广东花卉产业可持续发展．
THAP8基因在卵巢癌组织中的表达及其临床意义

在妇科肿瘤中，卵巢癌的发病率居第3位，但其病死率却居首位~([1])，其发生涉及细胞生长、分裂、分化和凋亡等生命科学的根本问题．凋亡相关蛋白（thanatos-associated protein， THAP)家族属于转录因子家族，其通过调节细胞增殖、细胞周期、凋亡、基因转录、染色体修饰等活动~([2])，参与细胞分化和胚胎发育等生命过程~([3-4])．THAP8属于锌离子依赖的DNA结合蛋白，是THAP家族的新成员~([5-6])，其基因定位于染色体19q13.13，并在肺、肝、肾、甲状腺、胰腺和脑组织中 广泛表达．已有的研究表明，THAP8基因在神经系统肿瘤、肌肉和皮肤组织肿瘤中表达异常~([6])．国内外对于THAP8基因在其他肿瘤中的表达及其作用机制研究较少，其与卵巢癌发病的关系还不明确．本研究旨在观察THAP8基因在卵巢癌中的表达，探索其在卵巢癌的发生和发展中的作用．
卵巢癌的二元论模型及细胞起源与发病机制

近年来，随着病理学及分子生物学的发展，人们认识到卵巢癌是一个异质性疾病，存在多种组织学类型和不同的发病模式，不能单一应用一种发病模式来解释．以病理学形态观察及分子生物学为基础，根据卵巢癌不同的发病模式可将卵巢癌分为I型和Ⅱ型，即卵巢癌的二元论模型~([1])．二元论模型最完美的应用是在卵巢浆液性癌中，而对卵巢癌其他组织学类型的指导尚存在一些问题．因此，本文将针对二元论模型在浆液性癌以外的卵巢癌的适用性，以及不同类型卵巢癌的细胞起源和癌变生物学机制作一综述．
Percolation of Mobile Individuals on Weighted Scale-Free Networks

The percolation-like phase transition of mobile individuals is studied on weighted scale-free (WSF) networks, in which the maximum occupancy at each node is one individual (i.e. hard core interaction) and individuals can move to neighbor void node. Especially, the condition for the existence of a spanning cluster of individuals (a connected cluster of neighbor nodes occupied by individuals that span the entire systems) is investigated and it is found that there exists a critical value of weight coupling parameter β_c, above which the density threshold of individuals is zero and below which the density threshold is larger than zero for WSF networks in the thermodynamic limit N → oo. Furthermore, the finite size scaling analysis show that for certain value β, the percolation transition of mobile individuals on a WSF network belongs to the same universality class of regular random graph percolation.
Formation Mechanism of Micropores on the Surface of Pure Aluminum Induced by High-Current Pulsed Electron Beam Irradiation

The mechanism of micropores formed on the surface of polycrystalline pure aluminum under high-current pulsed electron beam (HCPEB) irradiation is explained. It is discovered that dispersed micropores with sizes of 0.1-1 μm on the irradiated surface of pure aluminum can be successfully fabricated after HCPEB irradiation. The dominant formation mechanism of the surface micropores should be attributed to the formation of supersaturation vacancies within the near surface during the HCPEB irradiation and the migration of vacancies along grain boundaries and/or dislocations towards the irradiated surface. It is expected that the HCPEB technique will become a new method for the rapid synthesis of surface porous materials.
Effects of a Premixed Layer on the Richtmyer-Meshkov Instability

The effects of a premixed layer on the Richmyer-Meshkov instability (RMI) are studied by setting a density gradient for the first shocked fluid in the RMI problems. The RMI with initial density gradients are simulated by using a high resolution arbitrary Lagrangian-Eulerian method. The effects of density gradient and gradient width are analyzed on the basis of the simulation results for the shock from a light fluid to a heavy fluid and for the shock from a heavy fluid to a light fluid. Overall, the premixed layer can suppress the perturbation growth, and the detailed effects are different depending on the detailed premixed configuration. The width of the premixed layer has a very light influence on the perturbation, while the density gradient has quite a significant effect on two kinds of RMIs.
Geometric and Electronic Structures at the Interface between Iron Phthalocyanine and Si (110)

The geometric and electronic structures at the interface between iron phthalocyanine (FePc) and Si(110) surface are studied by ultraviolet photoelectron spectroscopy and density functional theory (DFT) calculation. After FePc is deposited on Si(110), the emission features are located at 2.56, 4.90, 7.90, 10.88eV below the Fermi level for monolayer and 2.73, 4.90, 7.74, 10.52eV below the Fermi level for multilayer. At the coverage of 1 ML, FePc molecules are adsorbed on the bridge site in a flat-lying geometry with a 2.17? separation between the molecule and the substrate. The molecular plane is bent due to the interaction between the adsorbate and the substrate.
Effect of Interface Structure on Thermal Boundary Conductance by using First-principles Density Functional Perturbation Theory

We choose a Si/Ge interface as a research object to investigate the influence of interface disorder on thermal boundary conductance. In the calculations, the diffuse mismatch model is used to study thermal boundary conductance between two non-metallic materials, while the phonon dispersion relationship is calculated by the first-principles density functional perturbation theory. The results show that interface disorder limits thermal transport. The increase of atomic spacing at the interface results in weakly coupled interfaces and a decrease in the thermal boundary conductance. This approach shows a simplistic method to investigate the relationship between microstructure and thermal conductivity.
Perfect plane-wave source for a high-order symplectic finite-difference time-domain scheme

The method of splitting a plane-wave finite-difference time-domain (SP-FDTD) algorithm is presented for the initiation of plane-wave source in the total-field/scattered-field (TF/SF) formulation of high-order symplectic finitedifference time-domain (SFDTD) scheme for the first time. By splitting the fields on one-dimensional grid and using the nature of numerical plane-wave in finite-difference time-domain (FDTD), the identical dispersion relation can be obtained and proved between the one-dimensional and three-dimensional grids. An efficient plane-wave source is simulated on one-dimensional grid and a perfect match can be achieved for a plane-wave propagating at any angle forming an integer grid cell ratio. Numerical simulations show that the method is valid for SFDTD and the residual field in SF region is shrinked down to-300 dB.