mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
泌尿男生殖系统肿瘤多学科团队综合诊治组织与实施规范中国专家共识

泌尿男生殖系统肿瘤是一系列泌尿系统和男性生殖系统肿瘤的集合,包括发病率较高的三大肿瘤:前列腺肿瘤、膀胱肿瘤和肾脏肿瘤,以及睾丸肿瘤、阴茎肿瘤等少见肿瘤。近年来,我国前列腺癌的发病率呈现持续快速增长趋势,成为中国男性泌尿生殖系统发病率最高的肿瘤。前列腺癌正成为严重影响我国男性健康的泌尿系统恶性肿瘤,应引起充分重视;伴随烟草消费、工业化水平提高及人口老龄化,中国人膀胱癌发病率不论是男性还是女性,也不论在城市还是农村中,均呈现逐年增长趋势;我国肾癌的发病率和死亡率逐年增加,对居民生命健康的危害进一步加大。
RECURSIVE INTEGRAL METHOD FOR THE NONLINEAR NON-SELFADJOINT TRANSMISSION EIGENVALUE PROBLEM

The transmission eigenvalue problem is an eigenvalue problem that arises in the scattering of time-harmonic waves by an inhomogeneous medium of compact support. Based on a fourth order formulation, the transmission eigenvalue problem is discretized by the Morley element. For the resulting quadratic eigenvalue problem, a recursive integral method is used to compute real and complex eigenvalues in prescribed regions in the complex plane. Numerical examples are presented to demonstrate the effectiveness of the proposed method.
The greater roles of indigenous microorganisms in removing nitrobenzene from sediment compared with the exogenous Phragmites australis and strain JS45

The feasibility of using Phragmites australis-JS45 system in removing nitrobenzene from sediments was conducted. However, it was observed that nitrobenzene degraded rapidly and was removed completely within 20 days in native sediments, raising the possibility that indigenous microorganisms may play important roles in nitrobenzene degradation. Consequently, this study aimed to verify this possibility and investigate the potential nitrobenzene degraders among indigenous microorganisms in sediments. The abundance of inoculated strain JS45 and indigenous bacteria in sediments was quantified using real-time polymerase chain reaction. Furthermore, community structure of the indigenous bacteria was analyzed through high throughput sequencing based on Illumina MiSeq platform. The results showed that indigenous bacteria in native sediments were abundant, approximately 10~(14) CFU/g dry weight, which is about six orders of magnitude higher than that in fertile soils. In addition, the levels of indigenous Proteobacteria (Acinetobacter, Comamonada-ceae_uncultured, Pseudomonas, and Thauera) and Firmicutes (Clostridium, Sporacetigenium, Fusibacter, Youngiibacter, and Trichococcus) increased significantly during nitrobenzene removal. Their quantities sharply decreased after nitrobenzene was removed completely, except for Pseudomonas and Thauera. Based on the results, it can be concluded that indigenous microorganisms including Proteobacteria and Firmicutes can have great potential for removing nitrobenzene from sediments. Although P. australis -JS45 system was set up in an attempt to eliminate nitrobenzene from sediments, and the system did not meet the expectation. The findings still provide valuable information on enhancing nitrobenzene removal by optimizing the sediment conditions for better growth of indigenous Proteobacteria and Firmicutes.
慢性分泌性中耳炎两种治疗方案比较

慢性分泌性中耳炎是耳鼻咽喉科常见疾病之一,患者急性病程反复发作>12周即可确诊;该病以耳闷、耳鸣及耳内阻塞感为主要临床表现,如控制不及时可导致中耳粘连、听力下降甚至失聪,严重影响日常生活质量。慢性分泌性中耳炎发病机制尚未彻底阐明,大部分学者认为咽鼓管阻塞及功能障碍是疾病复发关键原因,临床治疗应将有效去除中耳积液、控制局部炎症和渗出作为主要治疗原则。目前手术联合激素已成为治疗慢性分泌性中耳炎临床首选方案,但采用何种术式更使患者受益尚无明确定论。本文旨在探讨鼓膜穿刺和经咽鼓管行地塞米松注射液注入,对慢性分泌性中耳炎患者骨导听阈、咽鼓管功能及水通道蛋白水平的影响,为选择临床治疗方案提供依据。
Computational insights into the subtype selectivity and "message-address-efficacy" mechanisms of opioid receptors through JDTic binding and unbinding

In drug design and discovery,binding affinity and selectivity are two basic properties of a drug candidate. Opioid receptors (ORs) are the main targets of strong analgesics. Like some other class A members of G-protein-coupled receptors (GPCRs), ORs exhibit complex selectivity on their ligands. The diversity of binding activity and selectivity among opioids has deeply attracted researchers for a long time. To investigate the subtype selectivity of µ, δ and κ ORs in detail, using the κ-selective antagonist JDTic as a probe, we performed a series of computational simulations, including molecular dynamics and metadynamics, on JDTic-µ/δ/κ-OR complexes. From the simulations, we found that the decisive factor of JDTic selectivity on the µ-subtype was the 2.63 position,which affected the efficacy of JDTic through changing the dynamics of the Q~(2.60) residue. In addition to the 2.63-position residue,the 7.35 position was the other crucial aspect of JDTic selectivity for the δ-subtype. Based on the results, we suggest a new concept, the "message-address-efficacy" hypothesis, to explain the relationships among the affinity, selectivity and function between ORs and opioids. Thus, all the detailed dynamics of JDTic-bound ORs might be helpful to deeply understand the subtype selectivity and binding mechanisms of other GPCRs.
Analysis of detection capabilities of LEO reconnaissance satellite constellation based on coverage performance

In the design problem of low earth orbit (LEO) reconnaissance satellite constellation, optimization of coverage performance is the design goal in most current methods. However, in the using process, the user only concerns with the detection capabilities rather than coverage performance. To establish the relationship between these two aspects, the reconnaissance processes of normal stochastic targets are considered and the mathematic models of detection processes are built. The indicators of coverage performance are used to evaluate the detection probability and expectation of detection time delay, which are important factors in reconnaissance constellation estimation viewed from military intelligence discipline. The conclusions confirmed by the final simulation will be useful in LEO reconnaissance constellation design, optimization and evaluation.
Multi-channel signal parameters joint optimization for GNSS terminals

Traditional global navigation satellite system (GNSS) terminals for satellite navigation adopt independent channels to track the signals from different satellites, which results in a lack of information interaction between the channels. Inspired by the vector tracking idea, and drawing lessons from the principle that in the position domain the Taylor expanded pseudorange observations can be used for positioning via the least squares method, this paper proposes a novel least squares-based multi-channel para-meter joint estimation (MPJE) method in the signal domain, which not only retains the advantages of channel fusion, but also maintains the flexibility and diversity of the localization algorithm. With achieving optimal carrier to noise ratio as the goal, the proposed method obtains the required code loop and carrier loop parameters for signal tracking in the domain of whole channels. Experimental results indicate that this method fully achieves the assistant fusion advantages of frequency lock loop (FLL), phase lock loop (PLL) and delay lock loop (DLL), making good use of the robustness and dynamic properties of the FLL and the measurement accuracy of the DLL, and is helpful for achieving stable and accurate signal tracking under weak signals and high dynamic stress environments.
80岁以上高龄患者行常规心脏手术疗效分析及随访结果

近年来,随着人们生活水平的提高和疾病预防意识的增强,预期寿命显著延长,心脏外科医师面临越来越多需要行心脏手术治疗的高龄患者,但是由于此类人群脏器储备功能较差,合并症多,临床医师做出手术决定往往较为困难,加之患者家属因惧怕手术风险而态度消极,使得相当一部分高龄心脏外科患者面临生活质量恶化和死亡的风险.而体外循环技术的改进和围手术期处理经验的增加使得高龄患者的心脏手术较以往更加安全,病死率和并发症发生率不断下降.
First stem cell transplantation to regenerate human lung

Lung-related diseases are the third-leading cause of human death throughout the world. Lethal lung diseases such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis and bronchiectasis are characterized by irreversible, progressive damage of the lung tissueg The ability to regenerate human lung tissue, if successful, would constitute a breakthrough in modern medicine. Despite years of research, however, currently there is no effective strategy to regenerate lost bronchioles or alveoli in humans. Stem cell-based regenerative medicine holds great potential for combating tissue damage in lung diseases and other disorders by providing unlimited materials for transplant (Liu et al., 2012; Liu et al., 2014; Wu and Izpisua Belmonte, 2016; Shi et al”2017; Yang et al.,2017). Induced pluripotent stem cells (iPSCs) could be the source of cells for autologous transplantation. iPSC has been successfully differentiated to alveolar and airway lineage (Huang et al.,2014; McCauley et al.,2017). It remains unknown however, whether these iPSC-derivatives can form lung tissue in vivo, and/or functionally contribute to gas-blood air exchange. In addition, undifferentiated iPSCs in the differentiation culture generate safety concerns. On the other hand, somatic stem cells or progenitors—if can be identified, isolated and expanded-could offer a better and safer choice for regenerative medicine.
腹部组合皮瓣在全手套脱伤修复中的应用研究

目的探讨腹部组合皮瓣修复全手套脱伤的治疗方法及临床疗效。方法自2010年2月至2014年3月,我们对12例全手套脱伤患者采用腹部组合皮瓣治疗,术中根据伤情进行腹部皮瓣组合修复,拇指单独修复,术后4周断蒂。结果术后皮瓣全部存活,随访时间为2~18个月,平均15个月,皮瓣质地柔软,外形较满意,感觉恢复S_11例,S_25例,S_36例。根据中华医学会手外科学会上肢部分功能评定试用标准评定手功能:优7例,良3例,可2例。结论应用腹部组合皮瓣修复全手套脱伤可以有效解决皮肤覆盖问题,恢复患手功能,是一种安全有效的治疗方法。
Morphological and chemical studies of artificial Andrographis paniculata polyploids

Andrographis paniculata (Burm. f.) Nees (AP) is commonly used for the treatment of many infectious diseases and has been cultivated widely in Asian countries, and has been included in United States Pharmacopoeia as a dietary supplement, but the cultivars of A. paniculata are not abundant due to its self-pollinated. With the aims to enrich AP resources and provide materials for after breeding we explored the polyploidy induction. Different explants, colchicine concentration, and treatment time were tested. After identification by flow cytometry, eleven polyploid plants with different morphologic traits were obtained. The agronomic traits and andrographolide concentration of the polyploids were improved greatly. One of the polyploids (serial 3-7) was chosen for further study. The traits of the second and third generation polyploids (serial 3-7) were stable. Compared with the normal plants, the seeds (2nd generation) weight increased by 31%, and the andrographolide concentration of the leaves increased by 14% (2nd) and 28% (3rd). In conclusion, AP autopolyploids with different morphologic traits were established successfully for the first time, and the polyploids induction might be effective for crop improvement of AP.
Field evidence of decreased extractability of copper and nickel added to soils in 6-year field experiments

The phytotoxicity of added copper (Cu) and nickel (Ni) is influenced by soil properties and field aging. However, the differences in the chemical behavior between Cu and Ni are still unclear. Therefore, this study was conducted to investigate the extractability of added Cu and Ni in 6-year field experiments, as well as the link with their phytotoxicity. The results showed that the extractability of added Cu decreased by 6.63 %(5.10%-7.90%), 22.5 %(20.6%-23.9%), and 6.87 %(0%-17.9%) on average for acidic, neutral, and alkaline soil from 1 to 6 years, although the phytotoxicity of added Cu and Ni did not change significantly from 1 to 6 years in the long term field experiment. Because of dissolution of Cu, when the pH decreased below 7.0, the extractability of Cu in alkaline soil by EDTA at pH 4.0 could not reflect the effects of aging. For Ni, the extractability decreased by 18.1 %(10.1%-33.0%), 63.0 %(59.2%-68.8%), and 22.0 %(12.4%-31.8%) from 1 to 6 years in acidic, neutral, and alkaline soils, respectively, indicating the effects of aging on Ni were greater than on Cu. The sum of ten sequential extractions of Cu and Ni showed that added Cu was more extractable than Ni in neutral and alkaline soil, but similar in acidic soil.
核电机组冷却塔配置与塔型优化探讨

核电机组的循环冷却水量巨大,冷却塔塔型基本选用逆流式自然通风冷却塔,冷却塔配置一般按1机1塔和1机2塔,而塔型优化牵涉因素较多,应根据塔型的比例关系拟定多组塔型参数,并对不同塔型进行热力、阻力计算,分析各种塔型参数对运行费用的影响,提出合理的进风口高度、淋水密度、淋水填料布置高度;对核电机组冷却塔配置与塔型优化的技术路线进行了探讨,并在此基础上进行了核电冷却塔配置的优选试算。
海生物暴发对核电厂冷源系统的影响分析及对策探讨

各类海生物的异常暴发,给核电厂冷源系统的正常运行带来了不利影响,甚至导致了机组降功率、跳机乃至紧急停堆等事件的发生,直接影响核电厂的经济性、可靠性及安全性。调研了海生物暴发对国内外核电厂取水安全产生影响的实例,分析国内外冷源系统安全相关的法规标准,结合我国滨海核电厂(以CPR1000堆型为例)的冷源系统实例,分析各核电厂目前采取应对海生物暴发的工程措施,旨在提出应对核电厂海生物暴发防范对策。结果表明,一方面关于潜在影响冷源系统安全的海生物调查法规的缺失,另一方面海生物暴发具有较大的不确定性,因此核电厂在应对海生物暴发问题上难度非常大,在防范对策上应尽可能采用多种手段。
钢铁企业余热余能发电机组循环水泵房加药系统改造及应用

通过对发电汽轮机凝汽器由原来的胶球机械清洗改造为集中加药式水流自动清洗,彻底解决发电机组冷却设备换热管内壁黏附菌类、藻类及粘泥的问题,对钢铁企业的自备电厂的中小型发电机组具有借鉴和推广意义。
化学产品工程的现状与趋势———代专辑前言

化学产品的开发始终是化学家和化学工程师的一项主要任务,但化学产品工程概念的提出则是在2000年前后。一批美欧化工界的学者在探索21世纪化学工程学科发展方向时认识到,全球化学工业重心正在发生重大的转变。一方面,大宗基础化学品的生产虽因世界经济的发展仍在扩大,但已开始渐趋饱和,利润空间不断缩小;另一方面,随着信息技术、现代交通、生物医药和新能源等产业的发展,市场对包括化工新材料在内的各种专用化学品的需求量却不断增加。化工生产正在由资源的初加工向深度加工的方向发展。许多大型跨国化工公司纷纷进行核心产业的转移,以适应市场需要和追求高额利润。据此,他们提出将化学产品工程作为化学工程的一个新的前沿领域。其中代表性的有美国Princeton大学韦潜光的重要报告“产品工程:化学工程发展的第三个里程碑?”。同时期,也有一些学者在重要的化工学术刊物发表了一批学术评论,阐述了化学产品工程研究的基本问题及对化学工程学科的提升作用;并指出,传统的化学工程多关注产品的生产过程,而化学产品工程则更强调产品的创新设计,以满足市场对产品特定性能或功能的需求。他们认为,化学产品工程应涵盖新产品的发现、设计、开发、制造与营销的全过程,范围极为广泛。我国学者也十分重视化学产品工程这一新兴学科的兴起与发展,分别从各自的研究方向出发相继发表了一些评述性论文,并多次组织召开学术研讨会,进行化学产品工程学科内涵与发展趋势的探讨。
Diabetes, its impact on peripheral nerve regeneration: lessons from pre-clinical rat models towards nerve repair and reconstruction

The global number of patients with type 1 and type 2 diabetes is about to increase substantially in the coming decades. The reasons for this are two-fold, at first there is actual increase in incidence of type 1 diabetes and at second there is global increase in living expectancy and a high prevalence of patients with type 2 diabetes among the elderly. The diabetic condition is affiliated with reduced peripheral nervous system maintenance, such as peripheral neuropathies (Juster-Switlyk and Smith, 2016) that may be more common in men.
Brain injury and neural stem cells

Many therapies with potential for treatment of brain injury have been investigated. Few types of cells have spurred as much interest and excitement as stem cells over the past few decades. The multipotentiality and self-renewing characteristics of stem cells confer upon them the capability to regenerate lost tissue in ischemic or degenerative conditions as well as trauma. While stem cells have not yet proven to be clinically effective in many such conditions as was once hoped, they have demonstrated some effects that could be manipulated for clinical benefit. The various types of stem cells have similar characteristics, and largely differ in terms of origin; those that have differentiated to some extent may exhibit limited capability in differentiation potential. Stem cells can aid in decreasing lesion size and improving function following brain injury.
足部烧伤患者弹力鞋的设计与应用

足部烧伤患者早期下床活动,静脉回流障碍,瘢痕部位呈紫黑色,严重者可产生水疱,水疱破裂易导致新生创面,且烧伤后期易发生瘢痕增生、挛缩甚至导致畸形.目前,烧伤患者下床活动穿戴的鞋子多为常见的拖鞋,拖鞋穿戴时易脱落,鞋子松紧度不可随意调节,不具有抑制瘢痕等功效.为便于烧伤患者早期下床活动,同时能够抑制烧伤后期的瘢痕增生,笔者单位设计了一款适合足部烧伤患者穿戴的弹力鞋(专利号:ZL201720294641.1),临床应用于62例烧伤患者,效果良好,现介绍如下.
不同槐花炮制品中总黄酮含量的比较研究

目的优化槐花总黄酮提取工艺,比较不同槐花炮制品(生品槐花、炒制槐花、槐花炭)中总黄酮的含量差异。方法采用闪式提取辅助乙醇浸提法提取生品槐花总黄酮,观察乙醇浓度、料液比、提取电压对提取率的影响。通过正交试验确定最佳提取条件,并在该条件下比较不同槐花炮制品中总黄酮提取率的差异。结果闪式提取法提取槐花中总黄酮的最优工艺条件为:乙醇浓度65%,料液比70ml · g~(-1),提取电压90V。不同槐花炮制品中总黄酮提取率有明显的不同,炒制槐花最高(14.23%),其次为生品槐花(13.17%),最后是槐花炭(9.31%)。结论研究优化了闪式提取法提取槐花总黄酮的最佳工艺,并为深入理解不同槐花炮制品不同功效主治与总黄酮含量变化的关系提供了理论依据。
双参酮冠心片有效成分组方配伍比例研究

目的研究双参酮冠心片中西洋参总皂苷、丹参总酚酸提取物、山楂叶提取物3个有效组分的最佳配伍比例并进行验证试验。方法以小鼠抗乏氧试验和小鼠抗疲劳试验结果为指标,采用L_9(3~4)正交试验优选双参酮冠心片中西洋参总皂苷、丹参总酚酸提取物、山楂叶提取物3个有效组分的配伍比例,获得2个最优配伍组合,两个最优配伍组合分别设140 mg · kg~(-1)和70 mg · kg~(-1)两个剂量组以大鼠垂体后叶素所致急性心肌缺血试验验证最佳配伍比例的合理性。结果根据抗乏氧和抗疲劳试验得出的2个最优配伍组合,最优配伍1和最优配伍2(西洋参总皂苷、丹参总酚酸提取物、山楂叶提取物的比例分别为1: 1.5: 1.5和1: 1.5: 2),对垂体后叶素所致的大鼠急性心肌缺血均有一定的保护作用,且最优配伍1优于最优配伍2。结论双参酮冠心片西洋参总皂苷、丹参总酚酸提取物、山楂叶提取物治疗气虚血瘀型冠心病最佳配伍比例为1: 1.5: 1.5。
三系杂交晚稻新组合安优1668

安优1668是上饶市农业科学研究所利用安丰A与恢复系R668配组育成的籼型三系杂交晚稻新组合,2017年2月通过江西省农作物品种审定委员会审定(赣审稻20170023 )。
高产杂交中稻新组合M76优3301

M76优3301是福建农林大学作物学院与福建省农业科学院生物技术研究所合作,以M76A与闽恢3301配组而成的杂交中稻新组合,在福建省2 a区试中全生育期142.4 d,株高130.1 cm,结实率81.94%,平均产量9.42 t/hm~2,比对照Ⅱ优明86增产10.31%。2016年2月通过福建省品种审定。
籼型杂交稻新组合成优981高产制种技术

成优981是贵州省水稻研究所选育的中籼迟熟型三系杂交水稻新组合,具有高产、抗倒伏、抗病性强、适应性广等特点,根据亲本的特征特性和开花习性,尤其是,依据母本成丰A柱头活力较差而导致制种产量较低、种子生产成本较高是该组合产业化发展的主要制约因子的特点,结合多年来在福建的成功制种经验,总结出提高其制种产量的关键技术是合理安排父母本播差期、提高母本柱头活力和搞好人工辅助授粉等。
Experimental Study on Flow Boiling of Deionized Water in a Horizontal Long Small Channel

In this paper, an experimental investigation on the flow boiling heat transfer in a horizontal long mini-channel was carried out. The mini-channel was with 2 mm wide and 1 mm deep and 900 mm long. The material of the mini-channel was stainless. The working fluid was deionized water. The experiments were conducted with the conditions of inlet pressure in the range of 0.2-0.5 MPa, mass flux in the range of 196.57-548.96 kg/m2s, and the outlet vapor quality in the range of 0.2 to 1. The heat flux was in the range of 292.86 kW/m~2 to 788.48 kW/m~2, respectively. The influences of mass flux and heat flux were studied. At a certain mass flow rate, the local heat transfer coefficient increased with the increase of the heat flux. If dry-out occurred in the mini-channel, the heat transfer coefficient decreased. At the same heat flux, the local heat transfer coefficient would depend on the mass flux. It would increase with the mass flux in a certain range, and then decrease if the mass flux was beyond this range. Experimental data were compared with the results of previous studies. Flow visualization and measurements were conducted to identify flow regime transitions. Results showed that there were eight different kinds of flow patterns occurring during the flow boiling. It was found that flow pattern had a significant effect on heat transfer.
不同组织容积的远程缺血后适应的作用效应比较

缺血再灌注损伤的病理生理改变包括激活氧化还原反应和脂质过氧化反应,能量代谢受损。缺血后适应诱导心脏缺血再灌注损伤的保护作用。本研究结果显示不同组织容积诱导的心脏保护作用相当,表明组织容积大小没有决定性影响缺血后适应的作用效应。
DualSPHysics: A numerical tool to simulate real breakwaters

The open-source code DualSPHysics is used in this work to compute the wave run-up in an existing dike in the Chinese coast using realistic dimensions, bathymetry and wave conditions. The GPU computing power of the DualSPHysics allows simulating real-engineering problems that involve complex geometries with a high resolution in a reasonable computational time. The code is first validated by comparing the numerical free-surface elevation, the wave orbital velocities and the time series of the run-up with physical data in a wave flume. Those experiments include a smooth dike and an armored dike with two layers of cubic blocks. After validation, the code is applied to a real case to obtain the wave run-up under different incident wave conditions. In order to simulate the real open sea, the spurious reflections from the wavemaker are removed by using an active wave absorption technique.
大脑后动脉动脉瘤的血管内治疗

大脑后动脉动脉瘤在颅内所有动脉瘤中仅占0.7% ~ 2.3%。由于大脑后动脉迂曲的走行以及周围复杂的解剖关系,外科手术治疗此类动脉瘤往往具有较高的风险。随着血管内治疗技术的发展和材料的改善,这类动脉瘤越来越多经由血管内途径治疗。国内外文献报道,血管内治疗与传统手术治疗相比,具有较低的并发症发生率。血管内治疗的方式包括单纯的动脉瘤栓塞以及联合载瘤动脉同时栓塞。对于P1段动脉瘤,笔者采用单纯栓塞动脉瘤保留载瘤动脉;而对于P2段及其远端动脉瘤,由于大多数在影像学表现上具有夹层动脉瘤的特征,为防止术后复发,多数术者采用动脉瘤联合载瘤动脉同时栓塞的术式。本文回顾性纳入2010年3月至2016年6月温州市中西医结合医院神经外科收治的20例大脑后动脉P1段及其远端破裂动脉瘤的患者。根据本病的临床特点,结合文献分析血管内治疗的安全性和有效性。
《人体结构学》生殖系统课例研究及应用

课例研究是一种基于教师间合作的研究方式,强调教学反思,在已确定的研究范围内,从各教学环节中的细微变化出发,朝着明确的研究方向,解决具体问题。本院自2014年起深化基础医学课程改革,在系统化理念的指导下设立《人体结构学》新学科,其中包括《系统解剖学》和《组织学与胚胎学》2门课程。为了尽快适应这一改革举措,组织解剖学教研室和组胚教研室骨干教师成立了教学研究课题组,进行以系统为单位的系列化课例研究。教研室及学科教学计划之间进行适当穿插调整,使涉及师生不再视系统解剖学和组织胚胎学为两门独立课程,而是针对某个系统或器官,从解剖学、组织学以及胚胎发生学等不同研究角度来描述形态和过程。人体胚胎发生时空过程复杂交错,历来是医学生理解和青年教师授课的难点和薄弱环节,本课题围绕生殖系统的教学内容,在课前、课中、课后进行多项活动,包括教师之间、教师与学生之间的沟通、交流、对话、讨论,为人体结构学争取更佳的融合效果。
Unusual Quartz Phenocrysts in a Newly Discovered Porphyritic Granite near the Giant Dongping Gold Deposit in Northern Hebei Province, China

The giant Dongping gold deposit, situated in northern Hebei Province, is the first recognized deposit among the alkaline complex-hosted gold system in China. The gold deposits in the Dongping district are usually defined as alkaline rock-related gold deposits because they are hosted by the Middle Devonian Shuiquangou alkaline complex (SAC). However, geochronological data show that these gold deposits were formed in Late Jurassic (Jiang Sihong and Nie Fengjun, 2000; Zhang Guorui et al., 2012).
超小钌原子簇负载Ⅲ-Ⅴ族氮化物纳米线光催化固氮反应

氮元素是构成生命体的一种基本元素,广泛存在于蛋白质、氨基酸及核苷酸中。由于稳定的氮氮三键的存在,绝大部分的有机体都无法直接利用大气的主要成分氮气。自然界中利用固氮细菌活化氮气,是将气态的游离氮分子转变为可被动植物吸收的化合态氮的主要过程,也被认为是比肩光合作用的另一种重要生化过程。人工固氮合成氨反应(N_2 + 3H_2 → 2NH_3),也称Haber-Bosch法,从发现距今己过百年。制备得到的氨气接下来可以继续转化为硝酸,氮肥,含氮炸药等重要化工原料,对人类社会的进步具有重大意义。不过,该方法基于铁基催化剂,需要在高温高压条件下才能实现较快的动力学过程,每年会消耗世界能源总量的1%以上。作为一个放热反应,开发较低工作温度的高效氮气活化催化剂,能在降低能源消耗的同时获得热力学的优势,提高平衡转化效率,是目前国际催化领域的热点和前沿课题之一。
选择性电催化剂提升使用高浓度甲醇为燃料的DMFCs操作性能

上述相关研究得到了国家自然科学基金(21376247, 21506225,21573240)和中科院过程工程所介尺度研究中心(COM2015A001)的资助。该研究工作近期己在Science Advances上在线发表。该工作表明使用选择性电催化剂,可以有效克服DMFC中甲醇渗透带来的负面效应,使组装的DMFC在使用高浓度甲醇为燃料时能够保持较高的功率密度输出。这种基于选择性电催化剂的设计思路为推广燃料电池商业化开辟了可行的途径。
儿童高白细胞性B淋巴细胞白血病治疗中继发血小板增多症1例报告

继发性血小板增多症(secondary thrombocytosis,ST)又称反应性血小板增多症,多由急慢性感染、贫血、脾切除手术、肿瘤、药物等原因诱发,一般无临床症状,在儿童阶段极少发生血栓。一般血小板计数(PLT)>400 × 10~9/L并证实有原发疾病即可诊断为ST。现对河北省廊坊市中医医院1例儿童急性高白细胞性B淋巴白血病治疗过程中出现ST的病例进行回顾分析。
解读国际泪膜与眼表协会2017年干眼专家共识中的干眼检查

总体而言,2017年DEWS Ⅱ中有关干眼的检查内容与我国《干眼临床诊疗专家共识(2013年)》 有较多相似之处,但是其指标更加量化,如采用DEQ-5或OSDI问卷作为量表筛选可能患有干眼的患者,然后进行下一步检查。泪液渗透压检查对我国干眼患者的诊断意义有待进一步探讨,相关设备有待引进。2017年DEWS Ⅱ没有对MGD检查进行细化介绍,但指出蒸发过强型或水液缺乏型干眼可以根据MGD表现、脂质层厚度、泪液动力学和泪液量评估及其严重程度进行分类,有助于干眼的治疗。
抗痴呆胆碱酯酶抑制剂的心血管胆碱能作用研究进展

目前胆碱酯酶抑制剂(ChEIs)被广泛运用于阿尔茨海默病(AD)的治疗,抗痴呆胆碱酯酶抑制剂主要有多奈哌齐、卡巴拉汀和加兰他敏。虽然这些药物的不良反应主要为胃肠道不良反应,但关于ChEIs治疗AD产生的QT间期延长和心动过缓等心血管胆碱能反应更为临床医生关注。目前也有不少抗痴呆胆碱酯酶抑制剂对心脏保护作用的报道,现对近年来的研究进展做回顾和总结。
2013年中国慢性病及其危险因素监测总体方案

随着我国社会经济的发展和人们生活方式的改变,以心脑血管疾病、恶性肿瘤、糖尿病和慢性阻塞性肺部疾病等疾病为主的慢性病已成为影响我国居民健康的重要公共卫生问题。开展中国慢性病及其危险因素监测,建立国家慢性病及其危险因素监测数据库,动态地掌握我国成人居民主要慢性病及其危险因素的流行现状和变化趋势,科学制定和评价慢病预防控制策略和措施效果已经成为慢性病防控的常规和基础工作。
A NOTE ON CONICAL KAHLER-RICCI FLOW ON MINIMAL ELLIPTIC KAHLER SURFACES

We prove that,under a semi-ampleness type assumption on the twisted canonical line bundle, the conical Kahler-Ricci flow on a minimal elliptic Kahler surface converges in the sense of currents to a generalized conical Kahler-Einstein on its canonical model. Moreover, the convergence takes place smoothly outside the singular fibers and the chosen divisor.
Fabrication and modeling of multi-layer metal–insulator-metal capacitors

This paper presents the fabrication and modeling for capacitance–voltage characteristics of multi-layer metal–insulator–metal capacitors. It is observed that, due the applied electric field, the effective dielectric constant of the stack was increased due to the accumulation of charges at the interface of high-to-low conductance materials. It is observed that the Maxwell–Wagner polarization is dominant at low frequencies (<10 kHz). By introducing carrier tunneling probability of the dielectric stack, the model presented in this paper shows a good agreement with experimental results. The presented model indicates that the nonlinearity can be suppressed by choosing the similar permittivity dielectric materials for fabrication of multilayer metal insulator metal capacitors.
A novel interface circuit for triboelectric nanogenerator

For most triboelectric nanogenerators (TENGs), the electric output should be a short AC pulse,which has the common characteristic of high voltage but low current. Thus it is necessary to convert the AC to DC and store the electric energy before driving conventional electronics. The traditional AC voltage regulator circuit which commonly consists of transformer,rectifier bridge, filter capacitor, and voltage regulator diode is not suitable for the TENG because the transformer's consumption of power is appreciable if the TENG output is small. This article describes an innovative design of an interface circuit for a triboelectric nanogenerator that is transformerless and easily integrated. The circuit consists of large-capacity electrolytic capacitors that can realize to intermittently charge lithium-ion batteries and the control section contains the charging chip,the rectifying circuit, a comparator chip and switch chip. More important, the whole interface circuit is completely self-powered and self-controlled. Meanwhile, the chip is widely used in the circuit, so it is convenient to integrate into PCB. In short,this work presents a novel interface circuit for TENGs and makes progress to the practical application and industrialization of nanogenerators.