mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Surface Roughness Around a 325-m Meteorological Tower and Its Effect on Urban Turbulence

Based on slow-and fast-response measurements under neutral stratification conditions from a 325-m meteorological tower located in a built-up area of north-central Beijing as well as a descriptive survey of surface roughness elements (i.e., buildings and trees) around the tower site, urban roughness lengths,z0, with zero-plane displacement height are estimated using logarithmic wind profile and morphometric methods in eight 45° directional sectors. When comparing their results with each other, the slow-response method tends to give smaller z0 values. At a given location, considerable directional variations in values are observed. The effect of surface roughness on urban turbulence characteristics in terms of non-dimensional standard deviations of three-component velocity, σi/u*1 (where i = u, v, v and u*1 is local friction velocity),is investigated.
Surface and Upper-Level Features Associated with Wintertime Cold Surge Outbreaks in South Korea

The surface and upper-level features associated with a sharp drop of wintertime daily temperature over South Korea is investigated in this study. This sharp drop in daily temperature is called a cold surge and is one of the most hazardous weather phenomena in East Asian winters. An upper-level baroclinic wave of 60° wavelength propagating eastward at a phase speed of 12° longitude per day across the continent of northern China from the west of Lake Baikal toward the eastern coast of China causes the outbreak of cold air over South Korea. The cooling associated with the upper-level baroclinic wave is found at all altitudes under the geopotential height-fall center near the tropopause. The development in the ridge seems to derive the early evolution of the eastward-propagating sinusoidal wave, whereas the trough is connected directly with the tropospheric temperature-drop. An enhancement of the wintertime East Asian jet stream after the outbreak of a cold surge is a response to the steep temperature gradient associated with the developing baroclinic wave.
Evaluation of East Asian Climatology as Simulated by Seven Coupled Models

Using observation and reanalysis data throughout 1961-1990, the East Asian surface air temperature,precipitation and sea level pressure climatology as simulated by seven fully coupled atmosphere-ocean models, namely CCSR/NIES, CGCM2, CSIRO-Mk2, ECHAM4/OPYC3, GFDL-R30, HadCM3, and NCARPCM, are systematically evaluated in this study. It is indicated that the above models can successfully reproduce the annual and seasonal surface air temperature and precipitation climatology in East Asia, with relatively good performance for boreal autumn and annual mean. The models' ability to simulate surface air temperature is more reliable than precipitation. In addition, the models can dependably capture the geographical distribution pattern of annual, boreal winter, spring and autumn sea level pressure in East Asia. In contrast, relatively large simulation errors are displayed when simulated boreal summer sea level pressure is compared with reanalysis data in East Asia. It is revealed that the simulation errors for surface air temperature, precipitation and sea level pressure are generally large over and around the Tibetan Plateau. No individual model is best in every aspect. As a whole, the ECHAM4/OPYC3 and HadCM3 performances are much better, whereas the CGCM2 is relatively poorer in East Asia. Additionally, the seven-model ensemble mean usually shows a relatively high reliability.
临床路径在椎间盘镜治疗腰椎间盘突出症中的应用

目的探讨临床路径在椎间盘镜治疗腰椎间盘突出症中的实施效果,为患者选择最佳的医疗、护理模式.方法将40例实施临床路径后患者的平均住院天数、平均医疗费用、功能恢复及患者满意度进行比较.结果患者平均住院天数由过去的14d左右下降至10.32d±2.16d,平均医疗费用由6812元左右下降至5892.60元±463.23元,平均术后首次功能锻炼时间由20.14h下降至12.37h,患者满意度由95%上升至97.5%.结论临床路径作为一种科学的医疗护理模式,在临床实践中切实可行,值得推广.
秋延晚辣椒与小麦高效栽培模式

贵州毕节地区种植业以旱地农业为主体,旱地作物传统种植模式多为小麦与玉米(烤烟)一年两熟制.为了增加农民收入,调整农业种植结构,几年来笔者进行了秋延晚辣椒与小麦高效栽培模式的试验及调查研究.通过示范与推广,系统总结出一套全年高效种植模式,现已推广667 hm2,年产辣椒约3万t,销售收入3000多万元.与传统种植模式相比大大提高了单位面积产值,使大批农民脱贫增收,并为辣椒加工企业提供了大量原料,取得显著的经济和社会效益.
施用烯效唑对杂交油菜产量的影响

在油菜生产上常常因苗床播种量过大,而导致高脚苗产生,造成油菜早薹、早花和倒伏现象,严重影响油菜单产.因此,为解决生产上这一难题,笔者于2002年在贵州省凤冈县蜂岩镇,选用新型植物生长调节剂--5%烯效唑在油菜不同时期进行喷施试验,观察对油菜生长的影响.……
不同玉米基因型吸钾和耐低钾能力的研究

利用植物对环境的遗传多样性,充分发掘优良基因型,筛选和利用吸钾能力强以及对土壤和肥料中钾利用效率高的作物品种,以适应低钾土壤条件,节约钾肥资源,缓解钾肥短缺矛盾[1 - 3].玉米是需钾量较多的作物,开展不同玉米基因型吸钾和耐低钾能力研究,挖掘玉米优良种质资源,以期为筛选吸钾能力强和耐低钾的玉米基因型,缓解我国钾肥不足提供依据.……
土壤微生物生物量和呼吸强度对大气CO2浓度升高的响应

　随着全球环境变化对陆地生态系统的影响逐渐成为公众和科学界关注的热点,CO2作为一种重要的温室气体受到格外重视.大气CO2浓度升高将直接影响陆地植物的光合作用[1].植物的光合产物约有20% ～ 50%被运送到地下,通过根系分泌及死亡输入土壤[2],因此大气CO2浓度升高将会间接影响土壤生态系统.长期以来,关于大气CO2浓度升高对农作物地上部分的研究较多,但关于大气CO2浓度升高对土壤特别是土壤微生物的影响的研究报道较少.
颅内海绵状血管瘤(附15例报告)

目的探讨颅内海绵状血管瘤的临床表现、影像学特征、诊断及治疗.方法对1993～2004年我院收治的15例海绵状血管瘤进行回顾性分析.结果15例均行手术治疗,病理确诊为海绵状血管瘤.其中位于脑叶内6例,病灶均全切除;位于脑干3例,2例全切除,1例部分切除;位于海绵窦内3例,2例部分切除,1例仅取活检,行栓塞术;位于颅底3例,2例全切除,1例部分切除.术前头颅CT和MR增强扫描提示肿瘤呈均一性显著强化,边缘清晰.其中12例行MR检查,9例考虑为海绵状血管瘤;15例行CT检查,显示为占位性病变.手术无1例死亡,疗效较满意.结论海绵状血管瘤术前诊断主要靠影像学检查,但位于颅底和海绵窦常误诊为脑膜瘤;手术是主要的治疗方法,能否全切除与病变位置有直接关系.
中国儿童孤独症家系外周血淋巴细胞永生细胞系的建立

目的试图建立外周血淋巴细胞、永生化细胞系以保存孤独症患者家系特有的基因组资源,为进一步探讨孤独症的发生机理提供材料.方法在知情同意的情况下收集66个原发性孤独症核心家系成员的外周血样品,采用EB病毒转化技术,将外周血B淋巴细胞转化成永生化淋巴母细胞系;并用遗传学方法检测其建系前后的遗传稳定性.结果建系成功孤独症病例60例,父母成功132例,所有建成的细胞系冻存后复苏成功率100%,染色体核型分析表明建系前后遗传是稳定的.结论本研究建立的孤独症患者永生细胞系,可为进一步研究孤独症的分子水平发病机理提供随时可取的实验材料.
奥沙利铂联合5-FU/CF治疗转移性大肠癌24例临床分析

目的观察奥沙利铂(oxaliplatin,L-OHP)联合5-FU/CF治疗24例晚期大肠癌的疗效及不良反应.方法用L-OHP 130 mg/(m2·d1)联合5-FU 500 mg/(m2·d1～d4)/CF 200 mg/(m2·d1～d4)方案治疗24例转移性大肠癌,分别评价近期疗效及不良反应.结果 24例受治者有效率为45.8%.主要不良反应为末梢神经炎和轻度骨髓抑制.Ⅲ度毒副反应主要为血小板的下降和腹泻.结论 L-OHP联合5-FU/CF治疗晚期大肠癌安全有效.
周期性动眼神经麻痹1例报告

周期性动眼神经麻痹(oculomotor palsy with cyclic spasms)是一种罕见的发育异常导致的疾病,表现为受累眼动眼神经支配的肌肉发生周期性痉挛和麻痹.Rampholdi于1884年首先报道为动眼-眼睑异常,此后国外陆续有数十例报道,迄今国内报道不到10例.现报道1例如下.
冷冻联合rhTNF-α治疗C6大鼠脑胶质瘤的实验研究

目的探讨冷冻联合rhTNF-α治疗C6大鼠脑胶质瘤的可行性.方法借助于立体定位技术,将C6胶质瘤细胞接种于40只雄性Wister大鼠脑S1区,待肿瘤长至第15天,直径约6 mm时,随机将荷瘤鼠分为四组:G1、G2、G3、G4分别为盐水对照组、冷冻治疗组、rhTNF-α治疗组及联合治疗组,每组10只,同时分别行相应的治疗.治疗后第15天,行核磁共振(MRI)检查,测量肿瘤体积和抑瘤率.动态观察各组荷瘤鼠生存期和rhTNF-α对荷瘤鼠的毒副作用.结果联合治疗组肿瘤体积和生存期与其它各组相比差异有显著性,且该组对肿瘤生长的抑制率(89.5%)明显大于冷冻组(66.3%)和rhTNF-α治疗组(49.0%),且大于理论抑瘤率(82.8%).同时观察到rhTNF-α对实验动物有一定毒副作用.结论冷冻和rhTNF-α联合应用,具有协同抗肿瘤作用,为进一步临床研究提供了实验依据.
An Invariance for (2+1)-Extension of Burgers Equation and Formulae to Obtain Solutions of KP Equation

In this article, we study the (2+1)-extension of Burgers equation and the KP equation. At first, based on a known Backlund transformation and corresponding Lax pair, an invariance which depends on two arbitrary functions for (2+1)-extension of Burgers equation is worked out. Given a known solution and using the invariance, we can find solutions of the (2+1)-extension of Burgers equation repeatedly. Secondly, we put forward an invariance of Burgers equation which cannot be directly obtained by constraining the invariance of the (2+ 1)-extension of Burgers equation.Furthermore, we reveal that the invariance for finding the solutions of Burgers equation can help us find the solutions of KP equation. At last, based on the invariance of Burgers equation, the corresponding recursion formulae for finding solutions of KP equation are digged out. As the application of our theory, some examples have been put forward in this article and some solutions of the (2+ 1)-extension of Burgers equation, Burgers equation and KP equation are obtained.
李希霍芬与中国之地质工作

编者按文章原稿系用英文写成,曾载<中国地质学会会志>1933年第3期,以纪念李希霍芬百年诞辰.原文由李海晨汉译刊登于<方志月刊>1933年第6卷第12期,37～38页.今年为李希霍芬逝世100周年,本刊重新刊发李海晨翻译的文章,介绍李希霍芬对中国地质所做出的贡献以及他的科学精神,以激励有志的年轻学者.
雷咪普利引起阴囊水肿1例

患者,男,46岁,以发作性胸痛1 个月入院,诊断为急性前壁心肌梗死.冠状动脉造影示左主干病变及三支病变,行冠状动脉旁路移植术.术后应用雷咪普利1 d 出现阴囊水肿,请皮肤科医生会诊后给予0.1%利凡诺湿敷不见好转,停用雷咪普利1 d后阴囊水肿消失.
全球大震和中国及邻区中强震地震活动 (2005年2～3月)

本目录中的地震参数来自"中国地震台站观测报告"(简称"月报").其中,国内及邻区给出M≥4.7的事件,全球给出M≥6的事件."月报"由中国地震台网中心按月做出.……
T优300在湘西龙山试验示范表现及高产栽培技术

T优300是湖南杂交水稻研究中心用T98A与恢复系300配组而成的中熟杂交水稻新组合.2003年与2004年在龙山县试验示范种植,单产分别为705.2 kg/667 m2与705.5 kg/667 m2,表现出丰产性好、适应性强、熟期适宜、生长势强、穗大粒多、结实率高、抗逆性强、米质优等特点,适合在龙山县种植金优58的地区推广.
Solubilization of Rock Phosphate in Liquid Culture by Fungal Isolates from Rhizosphere Soil

Rock phosphate (RP) is a low efficiency P fertilizer that is directly applied to the soil and can be solubilized by phosphate-solubilizing microorganisms (PSMs) in fermentation or soil conditions. This study investigated dynamic solubilization of 2 concentrations of rock phosphate in a liquid culture with different dosages of glucose by two fungal isolates,Aspergillus niger P39 and Penicillium oxalicum P66, from soybean and wheat rhizosphere soil. Although during the 20day culture period A. niger P39 had a stronger ability to acidify the culture media than P. oxalicum P66, soluble P concentrations at glucose dosages of 30 and 50 gL-1 with RP of 15 g L-1 in the culture solution were much higher by P. oxalicum P66. The greater effectiveness of P. oxalicum P66 compared to A. niger P39 in the solubilization of RP was strongly associated with the production of organic acids. This study suggested that for RP solubilization the type rather than the concentration of PSM-produced organic acids was more important.
Mineral Coated Fertilizer Effect on Nitrogen-Use Efficiency and Yield of Wheat

A field experiment with winter wheat (Triticum aestivum L.) was conducted on a silt loam calcaric endorusti-ustic Cambosols derived from the Yellow River alluvial deposits in Henan, China, from 2001 to 2002 to evaluate N recovery and agronomic performance of different mineral coated fertilizers (MiCFs) compared to normal urea used in wheat cropping systems under field conditions. Five treatments, including CK (check, no N fertilizer), urea and three different MiCFs at an equivalent N application rate were established in a randomized complete block design. N release from MiCFs in soil was more synchronous with the N requirement of wheat throughout the growth stages than that from urea, with grain yield of the MiCF treatments significantly higher (P ＜ 0.05) than that of the treatment urea. Correspondingly, the N recovery rate was greater for all MiCFs compared to urea, increasing from 32.8% up to 50.1%. Due to its high recovery and low cost, use of the mineral coated N fertilizers was recommended instead of the polymer coated N fertilizers.
Dissolution of Aluminum in Variably Charged Soils as Affected by Low-Molecular-Weight Organic Acids

Low-molecular-weight (LMW) organic acids exist widely in soils and play an important role in soil processes such as mineral weathering, nutrient mobilization and Al detoxification. In this research, a batch experiment was conducted to examine the effects of LMW organic acids on dissolution of aluminum in two variably charged soils, an Ultisol and an Oxisol. The results showed that the LMW organic acids enhanced the dissolution of Al in the two investigated soils in the following order: citric ＞ oxalic ＞ malonic ＞ malic ＞ tartaric ＞ salicylic ＞ lactic ＞ maleic. This was generally in agreement with the magnitude of the stability constants for the Al-organic complexes. The effects of LMW organic acids on Al dissolution were greater in the Ultisol than in the Oxisol as compared to their controls. Also, the accelerating effects of citric and oxalic acids on dissolution of Al increased with an increase in pH, while the effects of lactic and salicylic acids decreased. Additionally, when the organic acid concentration was less than 0.2 mmol L-1, the dissolution of Al changed little with increase in acid concentration. However, when the organic acid concentration was greater than 0.2 mmol L-1,the dissolution of Al increased with increase in acid concentration. In addition to the acid first dissociation constant and stability constant of Al-organic complexes, the promoting effects of LMW organic acids on dissolution of Al were also related to their sorption-desorption equilibrium in the soils.
急诊CT诊断创伤性膈疝合并脾肺复合性损伤一例

患者男,48岁.因坠落伤急诊入院.主诉:左胸、腹部及腰、背部剧烈疼痛伴呼吸困难.体检:痛苦面容,神清合作,无呕吐、咳血,无大小便失禁,左胸及上腹部压痛,左胸部可扪及骨擦音,左肺呼吸音减弱.Bp 120/70 mmHg,R 28/分,P 100/分.临床以"闭合性胸腹部钝性伤"申请急诊CT检查.
Effect of Nitrogen Fertilizers on Movement and Transformation of Phosphorus in an Acid Soil

The effects of two different nitrogen fertilizers (urea and NH4Cl) with monocalcium phosphate (MCP) on the movement and transformation of fertilizer P in soil microsites along with soil pH changes at different distances from the fertilizer application site were studied in an incubation experiment. A highly acidic red soil (Ultisol, pH 4.57) from south China with MCP fertilizer alone or in combination with NH4Cl or urea was added to the surface of soil cylinders and packed in wax blocks. After 7 and 28 days, the extraction and analysis of each 2 mm layer from the interface of the soil and fertilizer showed that added NH4Cl or urea did not change the movement distance of fertilizer P. However, P transformation was significantly affected (P ＜ 0.05). After 7 days, at 0-8 mm distance from the fertilizer site the addition of urea significantly decreased the water-extractable P concentration; however, after 28 days the effect of N addition had disappeared. Also,at limited distances close to the fertilizer site NH4Cl application with MCP significantly increased acid-extractable P and available P, while with the addition of urea they significantly decreased. Compared with application of MCP alone,addition of urea significantly increased soil pH in fertilizer microsites, whereas the addition of NH4Cl significantly decreased soil pH.
Responses of Soil Microbial Community Structure and Diversity to Agricultural Deintensification

Using a scheme of agricultural fields with progressively less intensive management (deintensification), different management practices in six agroecosystems located near Goldsboro, NC, USA were tested in a large-scale experiment, including two cash-grain cropping systems employing either tillage (CT) or no-tillage (NT), an organic farming system (OR), an integrated cropping system with animals (IN), a successional field (SU), and a plantation woodlot (WO). Microbial phospholipid fatty acid (PLFA) profiles and substrate utilization patterns (BIOLOG ECO plates) were measured to examine the effects of deintensification on the structure and diversity of soil microbial communities. Principle component analyses of PLFA and BIOLOG data showed that the microbial community structure diverged among the soils of the six systems.Lower microbial diversity was found in lowly managed ecosystem than that in intensive and moderately managed agroecosystems, and both fungal contribution to the total identified PLFAs and the ratio of microbial biomass C/N increased along with agricultural deintensification. Significantly higher ratios of C/N (P ＜ 0.05) were found in the WO and SU systems, and for fungal/bacterial PLFAs in the WO system (P ＜ 0.05). There were also significant decreases (P ＜ 0.05)along with agricultural deintensification for contributions of total bacterial and gram positive (G+) bacterial PLFAs.Agricultural deintensification could facilitate the development of microbial communities that favor soil fungi over bacteria.
Spatial Characteristics of Soil Organic Carbon Storage in China's Croplands

The soil organic carbon (SOC) pool is the largest component of terrestrial carbon pools. With the construction of a geographically referenced database taken from the second national general soil survey materials and based on 1 546typical cropland soil profiles, the paddy field and dryland SOC storage among six regions of China were systematically quantified to characterize the spatial pattern of cropland SOC storage in China and to examine the relationship between mean annual temperature, precipitation, soil texture features and SOC content. In all regions, paddy soils had higher SOC storage than dryland soils, and cropland SOC content was the highest in Southwest China. Climate controlled the spatial distribution of SOC in both paddy and dryland soils, with SOC storage increasing with increasing precipitation and decreasing with increasing temperature.
小场地恶劣天气探空球施放技术

引言从2002年开始,中国气象局逐步对现有的高空"59-701"探测系统进行更新,将逐步换成L波段探测系统,该系统现已在杭州、上海、南京等36个高空站投入业务使用.该系统工作性能较稳定,功能较齐全,操作界面易懂,操作键易掌握,且自动化程度高,有效地减轻了值班人员的工作强度.
Supersonic Propagation of Heat Waves in Low Density Heavy Material

The propagation of a supersonic heat-wave through copper-doped foam with a density of 50 mg/cm3 was experimentally investigated. The wave is driven by 140 eV Holhraum radiations generated in a cylindrical gold cavity heated by a 2 k J, 1ns laser pulse (0.35 μm). The delayed breakout time of the radiation waves from the rear side of the foam is measured by a threechromatic streaked x-ray spectrometer (TCS) consisting of a set of three-imaging pinholes and an array of three transmission gratings coupled with an x-ray streak camera (XSC). With one shot,simultaneous measurements of the delays of the drive source and the radiation with two different energies (210 eV, 840 eV) through the foam have been made for the first time. The experimental results indicate that the time delays vary with photon energies. The radiation with an energy of 210 eV propagates at a lower velocity. The radiating heat wave propagates with a velocity that is larger than the sound speed. Using TGS, the transmitting spectrum was measured, and then lower limit of the optical depth which is more than 1, was obtained. The experimental data were in agreement with numerical simulations.
Impact of Toroidal Effect on Lower Hybrid Current Drive in Tokamak

The main topics concerning lower hybrid wave heating (LHH) and lower hybrid current drive (LHCD) in tokamak systems are presented. The inherent properties of tokamak the other hand, induce a consumption of wave energy by the trapped electrons, which reduce the current drive efficiency. The methods for the enhancement of the current drive efficiency may be derived from detailed analyses by drawing upon the ray tracing technology on toroidal geometry and the Fokker-Planck theory on velocity space.
鄂玉14高产栽培技术研究

研究结果表明:鄂玉14适宜西南山地玉米带二高山、低山种植;一般条件下鄂玉14最佳播期为4月上旬,最适种植密度为每公顷5.25万株,最佳施肥组合为每公顷N 138kg、P2O545kg、k2O90kg;栽培管理上应施足底肥、轻施苗肥、重施穗肥、巧施粒肥,加强苗期管理,注意防治大小斑病.
优质晚粳糯稻绍糯9714的选育及应用

绍糯9714属半矮生型优质晚粳糯稻品种,该品种熟期适中,产量较高,中抗稻瘟病、白叶枯病,稻米加工品质和糯性好.适宜在浙江、上海、江苏、湖北、安徽稻瘟病轻发区作单季晚稻种植.
抗胸腺细胞抗体对中华鳖免疫系统的影响

造成免疫系统抑制的常用手段包括电离辐射和环磷酰胺、可的松等药物处理.这类处理常常伴有较为广泛而严重的副作用,且对细胞免疫和体液免疫两者均有抑制效应.为专门研究T淋巴细胞及细胞免疫反应,可采用早期人工手术摘除胸腺,但这种处理特征是造成胸腺及细胞免疫活性彻底丧失且不可逆[1].此外,由于中华鳖(Trionyx sinensis)胸腺位于颈下部两侧,紧邻胸腔,与胸腔仅隔一薄膜[2],且身体被以较厚的背甲,人工摘除存在一系列复杂的技术环节并极易造成气胸、血胸.因此,通过制备抗中华鳖胸腺细胞血清,试图建立一种在体内专一性并可逆性抑制T淋巴细胞及细胞免疫低下的中华鳖实验模型,为实验病理学和免疫学研究奠定基础.
Effect of 7-hydroxystaurosporine on glioblastoma cell invasion and migration

Aim: To investigate the effect of 7-hydroxystaurosporine (UCN-01), a selective protein kinase C (PKC) inhibitor, on cell growth, migration, and invasion in invasive human glioblastoma U-87MG cells. Methods: PKC activity was determined based on the PKC-catalyzed transfer of the 32P-phosphate group from [γ-32P]ATP into a PKC-specific peptide substrate. Cell viability was measured by MTT assay. Cell invasion and migration were evaluated by a Boyden chamber assay and scratch wound assay, respectively. Protein expression was analyzed using Western blot assay. The formation of 3-dimensional cellular aggregates was examined by a cell-cell aggregation assay. Results: UCN-01 treatment resulted in concentration- and time-dependent inhibition of U-87MG cell growth at higher doses (>100 nmol/L), and reduced cell invasion and migration capability at less cytotoxic doses (<100 nmol/L). UCN-01 significantly repressed PKC activity. Consistent with this result, UCN-01 blocked cell invasion stimulated by phorbel 12-myristate-13-acetate (PMA) and ethanol (EtOH), 2 PKC activators. Enforced expression of the tumor suppressor genes BRCA1 and PTEN increased the anti-invasion potential of UCN-01. Exposure to UCN-01 caused a dose-dependent increase in cell adhesion molecule E-cadherin. The effect of UCN-01 on the formation of cell-cell aggregation was significantly reduced by the addition of an anti-E-cadherin antibody. Conclusion: UCN-01 inhibits the invasion and migration of human glioma cells. Accordingly, UCN-01 can have potential clinical applications for the treatment of human glioma metastasis.
Hepatocyte-like cells from directed differentiation of mouse bone marrow cells in vitro

Aim: To design the effective directed differentiation medium to differentiate bone marrow cells into hepatocyte-like cells. Methods: Bone marrow cells were cultured in the directed differentiation media including fibroblast growth factor-4 (FGF-4) and oncostatin M (OSM). Hepatocyte-like cells from directed differentiation of bone marrow cells were identified through cell morphology, RNA expressions by reverse transcriptase-polymerase chain reaction (RT-PCR), protein expressions by Western blot, and hepatocellular synthesis and metabolism functions by albumin ELISA, Periodic acid-Shiff staining and urea assay. Results: Some epithelial-like cells or polygonal cells appeared and increased in the course of the cell directed differentiation. Hepatocyte nucleur factor-3a (HNF-3a), albumin (ALB), cytokeratin 18 (CK18), transthyretin (TTR), glucose-6-phosphate (G-6-Pase), and tyrosine aminotransferase (TAT) mRNA were expressed in the course of the directed differentiation. The directed differentiated cells on d 21 expressed HNF-3a, ALB, and CK18 proteins. The directed differentiated cells produced albumin and synthesized urea in a time-dependent manner. They could also synthesize glycogen. Conclusion: Our differentiation media, including FGF-4 and OSM, are effective to differentiate bone marrow cells into hepatocyte-like cells, which could be used for hepatocyte resources for bioartificial liver or hepatocyte transplantation.
西门子双源Somatom Definition Flash CT心电图故障三则

故障分析和检修:无提示报错,ECG Monitor Demo mode不能显示,怀疑心电采集系统硬件故障。联系工程师进一步检测,PMM生理测量模块不良。更换PMM生理测量模块后,心电图信号正常显示。
环境大气污染物检测能力验证结果评价

环境大气污染物检测是环境监测工作的一个重要领域,随着环境监测技术水平的提高和环境保护工作的深入,大气中污染物的检测及质量控制工作越来越受到重视。为提高环境大气污染物检测能力,保证检测数据的准确性和可靠性,环境监测管理部门多次组织大气环境监测考核,考核项目涉及二氧化硫、一氧化氮、一氧化碳和苯系物等,考核样品均采用气体样品。
海南地区十例颅类鼻疽病患者临床特点

类鼻疽伯克霍尔德菌(burkholderia pseudomallei,BP)为革兰阴性需氧杆菌,所致的地方性人兽共患病称为类鼻疽病(meliodosis),是可导致多器官脓肿的一种疾病。以东南亚和澳大利亚北部为主要传染病区,颅类鼻疽虽然罕见,但病死率较高,颅类鼻疽临床表现多样,类似结核、真菌感染等。本文报道10例颅类鼻疽的临床特点,以加强对本病的认识及重视,早诊断、适当治疗。
基础研究提升传统作物谷子和黍稷的科研创新水平

谷子(Setaria italica Beauv.)和黍稷(Panicum miliaceum L.)是中国起源的古老农作物,栽培历史超过8 000年,粟(谷子)、黍(黍稷、糜子)、稻(水稻Oryza sativa L.)、麦(小麦Triticum aestivum L.)、菽(大豆Glycine max (Linn.) Merr.)被称为中国传统农耕文明的"五谷"[1-2],而谷子和黍稷在"五谷"中位列重要位置,可见这两种作物对中华文明发展的重要性。考古学证据的积累证明,黍稷的驯化早于谷子,在8 000以前的新石器时代黍稷就已经在黄河流域广泛栽培;而谷子的驯化略晚于黍稷,在距今6 000- 7 000年前被广泛栽培。已有证据表明,这两个作物均起源于中国北方的黄河流域,在水稻尚未传到北方,小麦尚未引入中国的农耕文化形成早期,对中华文明的形成起到了决定性作用,因此,谷子和黍稷被誉为中华民族的哺育作物[3-4],数千年来它们一直是中国北方旱作生态农业的主栽作物。随着小麦的引入特别是玉米(Zea mays L.)和甘薯(Dioscorea esculenta (Lour.) Burkill)引入中国后,谷子和黍稷的栽培面积逐渐减小,但仍然在旱作农业中占有重要地位,是干旱半干旱地区的主要作物。谷子黍稷均抗旱性突出,早在1927年,美国学者SHANTZ等[5]研究证明谷子和黍稷是禾谷类作物中水分利用效率最高的环境友好作物。随着世界范围的水资源减少和生态环境日益恶化,以及对水肥高消耗主栽作物所存在的环境恶化问题认识的加深,大家重新认识到谷子和黍稷在环境友好型可持续农业中的重要性,特别是谷子和其近缘野生种青狗尾草(Setaria viridis),因其小的二倍体基因组和易于实验室操作的株型,正在迅速发展成为世界广泛关注的抗旱耐逆研究和C4光合作用研究的模式作物[6-7]。
老年人非瓣膜性心房颤动诊治中国专家建议(2016)

心房颤动(房颤)是一种以快速、无序心房电活动为特征的室上性快速性心律失常。房颤在心电图上主要表现为P波消失,代之以不规则的心房颤动波(f波);RR间期绝对不规则。临床特点为心悸、脉律绝对不整。年龄是导致房颤发生的独立危险因素,65岁及以上人群的房颤特称老年房颤。根据患者房颤基础病情况,分为瓣膜性房颤和非瓣膜性房颤。非瓣膜性房颤是指无风湿性二尖瓣狭窄、机械/生物瓣膜、二尖瓣修复情况下发生的房颤。此专家建议只针对老年非瓣膜性房颤。
人参皂甙Rg1对HPV16 L2E6E7融合蛋白疫苗的免疫佐剂作用研究

宫颈癌(cervical carcinoma)是威胁女性健康的第二大恶性肿瘤,其危害程度仅次于乳腺癌。据国际癌症中心(International Agency for Research on Cancer,IARC)统计,全球每年宫颈癌的新发病例约为49.3万,死亡人数约为27.4万。Papovaviridae科的人乳头瘤病毒(human papillomaviruses,HPV)感染是导致宫颈癌发生的重要原因,目前已发现它有170多种亚型,而75%以上的宫颈癌患者感染了16、18、31和45型的HPV病毒。国际上正在积极研究防治宫颈癌的疫苗,目前已有3种预防性疫苗问世。HPV16 L2E6E7融合蛋白疫苗是针对HPV16病毒感染后E6E7癌基因引起的宫颈上皮内瘤样病变的一种治疗性疫苗,目前正在申报国家食品药品监督管理局药审中心(CDE)临床试验(受理号CXSL1200006)。像其他蛋白抗原一样,该疫苗尚存在免疫原性差的缺点。为提高该疫苗的免疫效果,本研究在HPV疫苗中添加人参皂甙Rg1,研究Rg1对HPV疫苗的佐剂作用。
2011—2014年广州市属及以下医疗机构放射工作人员证办理情况及问题分析

我国《放射工作人员职业健康管理办法》中明确规定,放射工作人员应当持有《放射工作人员证》,放射工作人员上岗前,放射工作单位负责向所在地县级以上地方人民政府卫生行政赫门为其申请办理。由于办理《放射工作人员证》(以下简称“办证”)所需材料包括了教育培训、职业健康监护和个人剂量监测,所以办证情况在一定程度上反映了医疗机构放射工作人员管理水平。广州市是我国的一线城市,经济发展水平高,放射工作人员数量多,本中心受上级卫生行政部门的委托,负责广州市属及以下医疗机构办证。自2011年开展此项工作以来,已为上千名放射工作人员办证,为了解本市医疗机构放射工作人员证的办理情况及管理存在的问题,特进行本次研究。
质量控制保证疼痛患者手术的疗效和安全

微创手术是慢性疼痛最有效的治疗手段之一,手术质量直接影响到疾病的治疗效果和患者的预后,质量控制应成为疼痛患者手术治疗的一个管理规范,从手术指征、手术技术到从业人员,各个环节都需要有严格的质量控制,如技术培训、规范、创新和准入等方面。