mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
高血压伴衰弱综合征的老年人血压控制的目标值

综上所述,对于高血压伴衰弱综合征的老年人,建议起始药物治疗的血压目标值为≥160/90 mmHg,血压控制目标值为140?150/70?90 mmHg,药物治疗后血压不宜低于130/60 mmHg,对于原本存在舒张压降低(单纯收缩期高血压、脉压差增大)的患者,注意药物治疗后舒张压不宜低于50 mmHg。期待有更多、更有力的临床研究来探索高血压伴衰弱综合征的老年人血压控制的目标值。
Solid oxide fuel cell interconnect design optimization considering the thermal stresses

The mechanical failure of solid oxide fuel cell (SOFC) components may cause cracks with consequences such as gas leakage, structure instability and reduction of cell lifetime. A comprehensive 3D model of the thermal stresses of an anode-supported planar SOFC is presented in this work. The main objective of this paper is to get an interconnect optimized design by evaluating the thermal stresses of an anode-supported SOFC for different designs, which would be a new criterion for interconnect design. The model incorporates the momentum, mass, heat, ion and electron transport, as well as steady-state mechanics. Heat from methane steam reforming and water–gas shift reaction were considered in our model. The results examine the relationship between the interconnect structures and thermal stresses in SOFC at certain mechanical properties. A wider interconnect of the anode side lowers the stress obviously. The simulation results also indicate that thermal stress of coflow design is smaller than that of counterflow, corresponding to the temperature distribution. This study shows that it is possible to design interconnects for an optimum thermal stress performance of the cell.
Study of oxygen fugacity during magma evolution and ore genesis in the Hongge mafic-ultramafic intrusion, the Panxi region, SW China

Economic concentrations of Fe-Ti oxides occurring as massive layers in the middle and upper parts of the Hongge intrusion are different from other layered intrusions (Panzhihua and Baima) in the Emeishan large igneous province, SW China. This paper reports on the new mineral compositions of magnetite and ilmenite for selected cumulate rocks and clinopyroxene and plagioclase for basalts. We use these data to estimate the oxidation state of parental magmas and during ore formation to constrain the factors leading to the abundant accumulation of Fe-Ti oxides involved with the Hongge layered intrusion. The results show that the oxygen fugacities of parental magma are in the range of FMQ-1.56 to FMQ+0.14, and the oxygen fugacities during the ore formation of the Fe-Ti oxides located in the lower olivine clinopyroxenite zone (LOZ) and the middle clinopyroxenite zone (MCZ) of the Hongge intrusion are in the range of FMQ-1.29 to FMQ-0.2 and FMQ-0.49 to FMQ+0.82, respectively. The MELTS model demonstrates that, as the oxygen fugacity increases from the FMQ-1 to FMQ+1, the proportion of crystallization magnetite increases from 11 % to 16 % and the crystallization temperature of the Fe-Ti oxides advances from 1134 to 1164 °C. The moderate oxygen fugacities for the Hongge MCZ indicate that the oxygen fugacity was not the only factor affecting the crystallization of Fe-Ti oxides. We speculated that the initial anhydrous magma that arrived at the Hongge shallow magma chamber became hydrous by attracting the H_2O of the strata. In combination with increasing oxygen fugacities from the LOZ (FMQ-1.29 to FMQ-0.2) to the MCZ (FMQ-0.49 to FMQ+0.82), these two factors probably account for the large-scale Fe-Ti oxide ore layers in the MCZ of the Hongge intrusion.
Multiphysics modeling of solid-oxide iron–air redox battery: analysis and optimization of operation and performance parameters

The present study reports a systematic computational analysis of the performance of solid oxide metalair redox battery operated at 800 and 550 °C using a recently developed high-fidelity multiphysics model. Two sets of parameters are particularly investigated: (1) operational parameters including current density and depth of discharge; (2) performance parameters including the chemical reaction kinetic rate constant of the redox cycle unit and exchange current density of the regenerative solid oxide fuel cell. These two groups of parameters are particularly analyzed with the goal to achieve high specific energy and round trip efficiency for SOIARB operated at different operating temperatures.
3D reconstruction size effect on the quantification of solid oxide fuel cell nickel–yttria-stabilized-zirconia anode microstructural information using scanning electron microscopy-focused ion beam technique

Self-made conventional nickel–yttria-stabilized zirconia composite anodes after reduction and 500 h operation were analyzed by three-dimensional microstructure reconstruction based on focused ion beam-scanning electron microscopy technique. Interfacial area, threephases- boundary density and phase volume fraction were measured based on the three-dimensional microstructure reconstruction to quantitatively study the statistical characterization of solid oxide fuel cell nickel–yttria-stabilizedzirconia anode microstructure before and after operation. It is found that for anode operated with long time, it is necessary to increase the corresponding three-dimensional reconstruction size to suppress the influence of microstructure variation caused by Ni agglomeration in order to obtain more accurate microstructural quantification information.
The Moon

Recent geochemical and geophysical data from the Moon enable a revision of earlier interpretations regarding lunar origin, structure and bulk composition. Earth and Moon show many similarities among their isotopic compositions, but they have evolved in totally dissimilar ways, probably related to the deficiency of water and volatile elements in the Moon as well as the vast differences in size and internal pressure. Some global geochemical differences from the Earth such as volatile depletion based on K/U ratios have been established. However, all current lunar samples come from differentiated regions, making the establishment of a bulk composition more reliant on bulk geophysical properties or isotopic similarities; it remains unclear how the latter arose or relate to whole Moon composition. The lack of fractionation effects among the refractory and super-refractory elements indicates that the proto-lunar material seems unlikely to have been vaporized while the presence of volatile elements may place lower limits on proto-lunar temperatures. The apparent lack of geochemical evidence of an impacting body enables other possible impactors, such as comets, to be considered. Although the origin of the Moon remains currently unknown, it is generally believed that the Moon originated as the result of a giant impact on the Earth.
Organic matter enrichment in the first member of the Xiagou formation of the lower Cretaceous in the Jiuquan Basin, China

The sources and enrichment of organic matter in a sediment core in the first member of the Xiagou Formation (K_1g~1) from the Chang 2-2 borehole of the Jiuquan Basin, NW China, have been examined using Rock-Eval, maceral, carbon isotopes and biomarker data. This data indicates that highly variable organic matter sources and preservation conditions in response to climate change. TOC content, HI, and δ~(13)C value were strongly correlated with the abundance of gammacerane, woody organic matter content, steranes/hopanes ratio, and C_(29) sterane content. This correlation demonstrates the importance that the control of the salinity of the depositional environment and organic matter sources can have upon the enrichment, type, and carbon isotopic composition of organic matter. In the Jiuquan Basin’s relatively high temperature and arid climate, high salinity lakes with high primary productivity of algae, planktons, and bacteria, and good organic matter preservation conditions (anoxic bottom water) resulted in the enrichment of isotopically-light algae-bacterial organic matter. In the Jiuquan Basin’s regions with a relatively low temperature and wet climate, fresh lakes with low primary productivity of algae, planktons, and bacteria received significant terrigenous high plants input, resulting in the deposition of a low abundance of isotopically heavier terrestrial organic matter.
How the optical timing system, the longitudinal diagnostics and the associated feedback systems provide femtosecond stable operation at the FERMI free electron laser

FERMI, the seeded free electron laser (FEL) in operation in Italy, is providing the User Community with unique fully coherent radiation, in the wavelength range 100–4 nm. FERMI is the first FEL fully synchronized by means of optical fibers. The optical timing system ensures an ultra-stable phase reference to its distributed clients. Several femtosecond longitudinal diagnostics verify the achieved performance; the bunch length monitor (BLM) and the bunch arrival monitor (BAM) will be presented in this paper. Feedback systems play a crucial role to guarantee the needed longterm electron beam stability. A real-time infrastructure allows shot-to-shot communication between front-end computers and the servers. Orbit feedbacks are useful in machine tuning, whereas longitudinal feedbacks control electron energy, compression and arrival time. A flexible software framework allows a rapid implementation of heterogeneous multiinput– multi-output (MIMO) longitudinal loops simply by selecting the appropriate sensors and actuators.
A BIM-GIS integrated pre-retrofit model for building data mapping

In response to rising energy costs and the impetus to reduce environmental impacts, upgrading the large building stock that is responsible for 40% of the total energy consumption to maximum energy efficiency is becoming an important task. Despite the many benefits associated with retrofit projects, they are still only slowly being implemented because of the many challenges that exist. One of these challenges is optimizing the decision between renovation scenarios based on economic and environmental goals, which can be made possible with an accurate pre-retrofit model. The intention of this paper is to introduce a pre-retrofit model that efficiently obtains and integrates multiple forms of building data as a critical step to develop a comprehensive understanding of a building to be renovated. Opportunities for utilizing building information modeling (BIM) and geographical information systems (GIS) for retrofitting projects were explored through the study of a historical campus building. With the use of as-is geometric data and as-is data, building data maps were obtained. The next step of this study is to use the model to conduct scenarios comparison and optimize renovation decision based on economic and environmental goals.
1:50 scale modeling study on airflow effectiveness of large spaces mutually connected for underground workshops

In the design of air conditioning and ventilation for an underground workshop, such as hydropower station underground powerhouse, mechanical ventilation was frequently applied to control air quality for large and mutually connected spaces of Dynamo floor, Generatrix floor, Hydraulic floor and Cochlea floor. In this paper, based upon the similarity criterion, the dimensionless yield criterion was used to explore the airflow effectiveness of large spaces mutually connected and a 1:50 small-scale model of the main powerhouse was built which was used to study and analyze the airflow distribution in large spaces mutually connected. A series of parameters was obtained from the experiment, and here we discussed following conditions: three air supply velocities: V/V_0=0.75, V/V_0=1 and V/V_0=1.25 (V_0 is the designed air velocity in this model) and three heat release rates: Q/Q_0=0.75, Q/Q_0=1 and Q/Q_0=1.25 (Q_0 is the designed heat load in this model). The environmental parameters of a workspace at different floors were acquired to study the effect of mechanical ventilation on the temperature field under different air velocities and heat release rates. The experimental results show that the heat release rate had a significant effect on the main power house temperature distribution. An appropriate air supply velocity could effectively optimize workplace temperature distribution under high-heat intensity environment. Energy efficiency coefficient and non-uniform temperature coefficient were predicted and the optimal design parameters (0.75V_0, 1Q_0) were recommended after 9 kinds of tests were conducted. The experimental research is helpful to the ventilation design of large and mutually connected spaces, such as Dynamo, Generatrix, Hydraulic and Cochlea floors in hydropower station underground powerhouse.
Are incidence and severity of clubfoot related to the season of birth?

Background: This study was designed to determine whether the occurrence of clubfoot follows a seasonal pattern in neonates from eastern and south-eastern China and to speculate the potential etiology of clubfoot. Methods: We reviewed 239 neonates with clubfeet during a period of 4 years as well as the monthly neonatal population of the Sixth National Population Census. Seasonal variations in terms of month of birth and severity were analyzed. Results: The incidence of clubfoot in neonates from eastern and south-eastern China showed seasonal variations, and the incidence was higher in autumn with a reference to the average birth rate in this corresponding area. No significant difference was found in severity of clubfoot. Conclusion: This seasonal pattern is of significant value to further understanding the etiology and pathogenesis of clubfoot in the corresponding area of China.
Effect of zinc supplementation on infants with severe pneumonia

Background: Pneumonia is a common respiratory infectious disease in infancy. Previous work shows controversial results on the benefit of zinc supplementation in patients with pneumonia. We conducted this study to investigate serum zinc status amongst infants with severe pneumonia and the clinical impact that zinc supplementation has on those patients with low serum zinc levels. Methods: This study design was a non-blinded prospective randomized controlled trial. The study is approved by the Ethics Committees of Beijing Children's Hospital. A total of 96 infants diagnosed with severe pneumonia and hospitalized in the pediatric intensive care unit between November 2011 and January 2012 were enrolled. Enrolled patients were divided into low serum zinc and normal serum zinc group. The low serum zinc group was randomized into treatment and control groups. Only the treatment group received zinc supplementation within 48-72 hours after hospitalization. Results: The prevalence of zinc deficiency on admission was 76.0%. The low zinc level was most apparent in infants between 1 and 3 months of age. The serum zinc level increased in the zinc treatment group and returned to a normal level (median, 53.20 μmol/L) on day 12±2. There was no statistical difference in the pediatric critic illness score, lung injury score, length of hospital stay, and duration of mechanical ventilation between the zinc treatment group and control group. Conclusions: Zinc deficiency is common in infants with severe pneumonia. Normalization of zinc levels with zinc supplementation did not improve clinical outcomes of infants with pneumonia.
Outcome in neonates with necrotizing enterocolitis and patent ductus arteriosus

Background: There is no agreement of the influence of patent ductus arteriosus (PDA) on outcomes in patients with necrotizing enterocolitis (NEC). In this study, we assessed the infl uence of PDA on NEC outcomes. Methods: A retrospective study of 131 infants with established NEC was performed. Outcomes (death, disease severity, need for surgery, hospitalization duration), as well as multiple clinical parameters were compared between NEC patients with no congenital heart disease (n=102) and those with isolated PDA (n=29). Univariate, multivariate and stepwise logistic regression analyses were performed. Results: Birth weight and gestational age were significantly lower in patients with PDA [median (95% CI): 1120 g (1009-1562 g), 28.4 wk (27.8-30.5 wk)] than in those without PDA [median (95% CI): 1580 g (1593- 1905 g), 32.4 wk (31.8-33.5 wk); P<0.05]. The risk of NEC-attributable fatality was higher in NEC patients with PDA (35%) than in NEC patients without PDA (14%)[univariate odds ratio (OR)=3.3, 95% CI: 1.8- 8.6, P<0.05; multivariate OR=2.4, 95% CI: 0.82-2.39, P=0.111]. Significant independent predictors for nonsurvival within the entire cohort were advanced disease severity stage III (OR=27.9, 95% CI: 7.4-105, P<0.001) and birth weight below 1100 g (OR=5.7, 95% CI: 1.7- 19.4, P<0.01). Conclusions: In patients with NEC, the presence of PDA is associated with an increased risk of death. However, when important differences between the two study groups are controlled, only birth weight and disease severity may independently predict mortality.
Heat shock protein 70-2 and tumor necrosis factor-α gene polymorphisms in Chinese children with Henoch- Schonlein purpura

Background: Henoch-Schonlein purpura (HSP) or IgAassociated vasculitis is related to immune disturbances. Polymorphisms of the heat shock protein 70-2 gene (HSP70-2) and the tumor necrosis factor-α gene (TNF-α) are known to be associated with immune diseases. The purpose of this study was to investigate the likely association of HSP70-2 (+1267A/G) and TNF-α (+308A/G) gene polymorphisms with HSP in children. Methods: The polymerase chain reaction restriction fragment length polymorphism method was used to detect the HSP70-2 and TNF-α polymorphisms in 205 cases of children with HSP and 53 controls; and the association of these polymorphisms with HSP and HSP nephritis (HSPN) was analyzed. Results: The G/G genotypic frequencies at the +1267A/G position of HSP70-2 in the HSP group (22.9%) were signifi cantly higher than those in the healthy control group (9.4%) (χ~2=4.764, P<0.05). The frequencies of the A/A, A/G and G/G genotypes of HSP70-2 in patients in the nephritis-free group and the HSPN group showed no statistically significant difference. The A/A genotype frequency at the +308G/A position of TNF-α in the HSP group was 8.3%, which was higher than that in the control group (χ~2=6.447, P<0.05). The A allele frequency of TNF-α in the HSP group was higher than that in the control group, with a statistically significant difference (χ~2=7.241, P<0.05). Conclusions: The HSP70-2 (+1267A/G) and TNF-α (+308G/A) gene polymorphisms were associated with HSP in children. The G/G homozygosity of HSP70-2 and the A/A homozygosity of TNF-α may be genetic predisposing factors for HSP.
Transplacental induction of fatty acid oxidation in term fetal pigs by the peroxisome proliferator-activated receptor alpha agonist clofibrate

Background: To induce peroxisomal proliferator-activated receptor α (PPARα) expression and increase milk fat utilization in pigs at birth, the effect of maternal feeding of the PPARα agonist, clofibrate (2-(4-chlorophenoxy)-2-methyl-propanoic acid, ethyl ester), on fatty acid oxidation was examined at full-term delivery (0 h) and 24 h after delivery in this study. Each group of pigs (n = 10) was delivered from pregnant sows fed a commercial diet with or without 0.8% clofibrate for the last 7 d of gestation. Blood samples were collected from the utero-ovarian artery of the sows and the umbilical cords of the pigs as they were removed from the sows by C-section on day 113 of gestation. Results: HPLC analysis identified that clofibric acid was present in the plasma of the clofibrate-fed sow (~4.2 μg/mL) and its offspring (~1.5 μg/mL). Furthermore, the maternal-fed clofibrate had no impact on the liver weight of the pigs at 0 h and 24 h, but hepatic fatty acid oxidation examined in fresh homogenates showed that clofibrate increased (P < 0.01) ~(14)C-accumulation in CO_2 and acid soluble products 2.9-fold from [1-~(14)C]-oleic acid and 1.6-fold from [1-~(14)C]-lignoceric acid respectively. Correspondingly, clofibrate increased fetal hepatic carnitine palmitoyltransferase (CPT) and acyl-CoA oxidase (ACO) activities by 36% and 42% over controls (P < 0.036). The mRNA abundance of CPT I was 20-fold higher in pigs exposed to clofibrate (P < 0.0001) but no differences were detected for ACO and PPARα mRNA between the two groups. Conclusion: These data demonstrate that dietary clofibrate is absorbed by the sow, crosses the placental membrane, and enters fetal circulation to induce hepatic fatty acid oxidation by increasing the CPT and ACO activities of the newborn.
Response to an Escherichia coli K88 oral challenge and productivity of weanling pigs receiving a dietary nucleotides supplement

Background: Dietary nucleotides, considered as antibiotics alternative, were shown to have positive effects on intestinal hyperaemia, systemic immunity, small-intestinal growth, and hepatic composition in pigs. However, there is no previous research on nucleotide supplementation in weanling pigs under an oral challenged E. coli K88. Therefore, 2 experiments were conducted to investigate the effects of dietary nucleotides on weanling pig growth performance, nutrient digestibility, fecal score, and blood profile after being orally challenged with E. coli K88. Methods: In Exp. 1, a total of 140 weanling pigs [8.33 ±0.33 kg of body weight (BW), 28-d old] were used in this 42-d feeding trial. Pigs were distributed into 1 of 4 treatments, 5 pigs/pen (3 barrows and 2 gilts) and 7 pens/treatment. Treatments were a control basal diet (CON) or the CON supplemented with 150 (R150), 220 (R220), or 275 (R275) mg/kg to give the three treatment diets. In Exp. 2,28 weanling pigs (BW = 8.40 ± 0.22 kg, 28-d old) were distributed into 1 of 4 treatments to give 1 pig/pen and 7 pens/treatment in a 42-d feeding and challenge trial. Dietary treatments were the same as in Exp. 1. On d 14, all those pigs (BW= 13.3±0.15 kg, 42-d old) were orally dosed with 1.5 mL suspension containing 10~(10) cfu/mL of E. coli K88. Twenty four hours after challenge, blood and excreta samples were collected from each pigs for analysis. Fecal scores were measured on d 7,14,21, and 28 of the study. Results: In Exp. 1, overall BW, average daily gain (ADG), gain/feed (G/F) ratio, and nutrient digestibilities were lower (P < 0.05) in CON group compared with the nucleotides fed pigs. In Exp. 2, after challenge, IgA, IgM, and IGF-I were higher (P < 0.05) in the nucleotide groups compared with CON. However, the nucleotide groups had lower (P < 0.05) cortisol and TNF-a compared with CON. Fecal E. coli counts and fecal score for the nucleotide groups were lower (P < 0.05) than for CON. Conclusions: In conclusion, dietary nucleotides supplementation could improve growth performance, nutrient digestibility, immune status, microbial balance, reduce diarrhea, and provide protection against enterotoxigenic E. coli K88 infection in weanling pigs.
Modeling and Prediction for the thrust on EPB TBMs under different geological conditions by considering mechanical decoupling

EPB TBMs (Earth pressure balance Tunneling Boring Machines) are extensively used in tunneling constructions because of its high efficiency and low disturbance on structures above ground. It is critically significant to predict the thrust acting on TBMs under different geological conditions for both the design of power system and the control of tunneling process. The interaction between the cutterhead and the ground is the core of excavation, through which geological conditions determine the thrust re-quirement combined with operating status and structural characteristics. This paper conducted a mechanical decoupling analysis to obtain a basic expression of the cutterhead-ground interactive stress. Then more engineering factors (such as cutterhead topological structure, underground overburden, thrusts on other parts, etc.) were further considered to establish a predicting model for the total thrust acting on a machine during tunneling. Combined with three subway projects under different geological conditions in China, the model was verified and used to analyze how geological, operating and structural parameters influence the acting thrust.