mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Alternative splicing of MaMYB16L regulates starch degradation in banana fruit during ripening

The alternative splicing of select genes is an important mechanism to regulate responses to endogenous and environmental signals in plants.However,the role of alternative splicing in regulating fruit ripening remains unclear.Here,we discovered that MaMYB16L,an R1-type MYB transcription factor,undergoes alternative splicing and generates two transcripts,the full-length isoform MaMYB16L and a truncated form MaMYB16S,in banana fruit.During banana fruit ripening,the alternative splicing process intensifies with downregulated MaMYB16L and upregulated MaMYB16S.Moreover,MaMY B16L is a transcriptional repressor that directly binds with the promoters of many genes associated with starch degradation and MaDREB2,a positive ripening regulator,and represses their expression.In contrast,MaMBY16S lacks a DNA-binding domain but competitively combines and forms nonfunctional heterodimers with functional MaMYB16L.MaMYB16L-MaMYB16S heterodimers decrease the binding capacity and transrepression activity of MaMYB16L.The downregulation of MaMYB16L and the upregulation of MaMYB16S,that is,a decreased ratio of active to non-active isoforms,facilitates the activation of ripening-related genes and thereby promotes fruit ripening.Furthermore,the transient overexpression of MaMYB16S promotes banana fruit ripening,whereas the overexpression of MaMYB16L delays this process.Therefore,the alternative splicing of MaMYB16L might generate a self-controlled regulatory loop to regulate banana fruit ripening.
Field experiment of rainfall infiltration on a soil slope and simulations based on a water-air two-phase flow model

Rainfall infiltration on a soil slope is usually an unsaturated seepage process that can be described by a water-air two-phase flow model. The effect of pore air pressure on rainfall infiltration has been widely recognized and validated by means of numerical simulations and laboratory experiments. However, whether a slope can actually seal pore air continues to be debated by researchers. In this study, a water-air two-phase flow model is used to simulate the rainfall infiltration process on a soil slope, and a field experiment is conducted to realistically test the sealing conditions of a slope. According to the numerical simulation, the areas of water and air flow in and out on the slope surface are relatively stable and can be classified as the “inhalation zone” and “overflow zone", respectively. Intermittent rainfall on the soil slope has an amplifying effect on pore air pressure because rainfall intensity is usually at the millimeter level, and it causes pore air pressure to reach the cm level. A field experiment was performed to determine whether a slope can realistically seal pore air and subsequently verify the regularity of rainfall infiltration. Air pressure sensors were buried in the slope to monitor the pore air pressures during the rainfall process. The monitoring results show that the pore air pressure in the slope changed, which indicates that the slope can seal air. Moreover, the amplification effects of intermittent rainfall on pore air pressure were observed for natural rainfall, which agrees well with the numerical simulation results.
Steam Pretreatment of Rice Hulls to Release Fermentable Saccharides: An Approach to Improve Recovery of (Hemi)Cellulosic Sugars Through Multivariate Design

The conversion of rice hulls into fermentable saccharides was explored through steam pretreatment employing 2.5% SO2. The interaction between temperature and time was assessed by means of the response surface method to achieve optimum contents of C6-sugars in water-insoluble solids (WIS) and C5-sugars in the liquor. Pretreatment carried out at 218 ºC for 2.3 min released liquor containing 55.4 g/L of sugars (29.1 g/L of xylose). In parallel, the WIS was subjected to enzymatic saccharification using different solid and enzyme loads via an experimental design: assays using 22.0% WIS and 20.0 filter paper units (FPU)/g led to 90.6 g/L of glucose, corresponding to a yield of 86.4% and an overall yield of 72.4%. The data reported are the highest ever found for such raw material, making it attractive to compete with conventional lignocellulosic biomass.
Contribution and Prospect of Erect Panicle Type to japonica Super Rice

Over the past 30 years, super rice played an important role in boosting rice yield. The phenotype of erect panicle (EP) architecture controlled by dense and erect panicle 1 (dep1) is the typical characteristic of super rice, and the phenotype has been used in rice breeding for nearly a century. In this review, the molecular genetic basis of EP phenotype, and mechanism of how dep1 affects rice carbon, nitrogen metabolism and grain quality (grain shape and taste quality) were discussed. In addition, we discussed the possible improvement strategies of rice yield and quality. This review provides a quick overview of the whole process for rice quality formation, as well as suggestions and ideas for future research on rice quality improvement.
Time-varying sliding mode control of missile based on suboptimal method

This paper proposes a time-varying sliding mode control method to address nonlinear missile body kinematics based on the suboptimal control theory. The analytical solution of suboptimal time-varying sliding surface and the corresponding suboptimal control law are obtained by solving the state-dependent Riccati equation analytically. Then, the Lyapunov method is used to analyze the motion trend in sliding surface and the asymptotic stability of the closed-loop system is validated. The suboptimal control law is transformed to the form of pseudo-angle-ofattack feedback. The simulation results indicate that the satisfactory performance can be obtained and the control law can overcome the influence of parameter errors.
New slant range model and azimuth perturbation resampling based high-squint maneuvering platform SAR imaging

Strong spatial variance of the imaging parameters and serious geometric distortion of the image are induced by the acceleration and vertical velocity in a high-squint synthetic aperture radar (SAR) mounted on maneuvering platforms. In this paper, a frequency-domain imaging algorithm is proposed based on a novel slant range model and azimuth perturbation resampling. First, a novel slant range model is presented for mitigating the geometric distortion according to the equal squint angle curve on the ground surface. Second, the correction of azimuth-dependent range cell migration (RCM) is achieved by introducing a high-order time-domain perturbation function. Third, an azimuth perturbation resampling method is proposed for azimuth compression. The azimuth resampling and the time-domain perturbation are used for correcting first-order and high-order azimuthal spatial-variant components, respectively. Experimental results illustrate that the proposed algorithm can improve the focusing quality and the geometric distortion correction accuracy of the imaging scene effectively.
Efficient C_2 Hydrocarbons and CO_2 Adsorption and Separation in a Multi-site Functionalized MOF

A multi-site functionalized microporous metal-organic framework (MOF), H[Zn_2(BDP)_(0.5)(ATZ)_3]·0.5H_2O·0.5DMF (1), was synthesized through mixed ligands strategy. The pore surface of complex 1 was modified by uncoordinated carboxylate O atoms, phenyl and pyridyl rings as well as-NH_2 groups, which strengthen interactions with C_2H_6, C_2H_4 and CO_2 molecules and lead to efficiently selective C_2H_6, C_2H_4 and CO_2 uptake over CH_4. The selective adsorption mechanism was discussed deeply based on Grand Canonical Monte Carlo (GCMC) simulations. It is expected that this study will provide a new perspective for the rational design and synthesis of MOFs with efficient gas adsorption and separation performance.
Rhodium(I)-Catalyzed Enantioselective C(sp~3)—H Functionalization via Carbene-Induced Asymmetric Intermolecular C—H Insertion

Transition-metal-catalyzed C—H insertion of metal-carbene represents an excellent and powerful approach for C—H functionalization. However, despite remarkable advances in metal-carbene chemistry, transition metal catalysts that are capable of enantioselective intermolecular carbene C—H insertion are mainly constrained to dirhodium(II) and iridium(III)-based complexes. Herein, we disclose a new version of asymmetric carbene C—H insertion reaction with rhodium(I) catalyst. A highly enantioselective rhodium(I) complex-catalyzed C(sp~3)—H functionalization of 1,4-cyclohexadienes with α-aryl-α-diazoacetates was successfully developed. By using chiral bicyclo[2.2.2]-octadiene as ligand, rhodium(I)-carbene-induced asymmetric intermolecular C—H insertion proceeds smoothly at room temperature, allowing access to a diverse variety of α-aryl-α-cyclohexadienyl acetates and gem-diaryl-containing acetates in good yields with good to excellent enantioselectivities (up to 99% ee). Furthermore, the synthetic utility of the reaction was highlighted by facile synthesis of a novel cannabinoid CB 1 receptor ligand. This method may offer a new opportunity for the development of therapeutically exploitable cannabinoid receptor type ligands in medicinal chemistry.
Dual Topological Features of Weyl Semimetallic Phases in Tetradymite BiSbTe3

Based on first-principles calculations and symmetry arguments, we reveal that the non-centrosymmetric ternary tetradymite BiSbTe3 possesses exotic dual topological features of Weyl semimetallic phases with Z2 index(1:000).The results show that the helical Dirac-type surface states protected by the time-reversal symmetry are present in the vicinity of the Brillouin zone center, which is consistent with the experimental report.Furthermore, we show that four pairs of Weyl points reside exactly at the Fermi level, which are guaranteed to be located on highsymmetry planes due to mirror symmetries.The helical surface states and the projected Weyl nodes are well separated in the momentum space, facilitating their observations in experiments.This work not only uncovers a unique quantum phenomenon with dual topological features in the tetradymite family but also paves a fascinating avenue for exploring the coexistence of multi-topological states with wide applications.
Concurrent Structural and Electronic Phase Transitions in V_2O_3 Thin Films with Sharp Resistivity Change

The relationship between structural and electronic phase transitions in V_2O_3 thin films is of critical importance for understanding of the mechanism behind metal-insulator transition(MIT)and related technological applications.Despite being extensively studied, there are currently no clear consensus and picture of the relation between structural and electronic phase transitions so far.Using V_2O_3 thin films grown on γ-plane Al_2O_3 substrates,which exhibit abrupt MIT and structural phase transition, we show that the electronic phase transition occurs concurrently with the structural phase transition as revealed by the electrical transport and Raman spectra measurements.Our result provides experimental evidence for clarifying this issue, which could form the basis of theoretical studies as well as technological applications in V_2O_3.
Thermal Stability of High Power 26650-Type Cylindrical Na-Ion Batteries

As a new electrochemical power system, safety(especially thermal safety)of Na-ion batteries(NIBs)is the key towards large-scale industrialization and market application.Thus, research on the thermal stability of NIBs is helpful to evaluate the safety properties and to provide effective strategies to prevent the occurrence of battery safety failure.Thermal stability of the high-power 26650 cylindrical NIBs using Cu-based layered oxide cathode and hard carbon anode is studied.The high power NIBs can achieve fast charge and discharge at 5-10C rate and maintain 80% capacity after 4729 cycles at 2 C/2C rate, where the unit C denotes a measure of the rate at which a battery is charge-discharged relative to its maximum capacity.The results of accelerating rate calorimeter and differential scanning calorimetry(ARC-DSC)test results show that NIBs have a higher initial decomposition temperature(≥110 °C)and a lower maximum thermal runaway temperature(≤350 °C)than those of Li-ion batteries(LIBs), exhibiting a favorable thermal stability.It should be noted that the heat generation of cathode accounts for a large proportion of the total heat generation while the thermal stability of the anode determines the initial thermal runaway temperature, which is similar to LIBs.Finally, the whole temperature characteristics of the NIBs in the range of-60 °C-1000 °C are summarized, which provide guidance for the safety design and applications of NIBs.
Coherent Control of High Harmonic Generation Driven by Metal Nanotip Photoemission

Steering ultrafast electron dynamics with well-controlled laser fields is very important for generation of intense supercontinuum radiation.It can be achieved through coherent control of the symmetry of the interaction between strong-field laser fields and a metal nanotip.We employ a scheme of two-color laser pulses combined with a weak static field to realize the control of a single quantum path to generate high harmonic generation from a single solid-state nanoemitter.Moreover, a smooth and ultrabroad supercontinuum in the extreme ultraviolet region is obtained, which can produce a single attosecond pulse.Our findings are beneficial for efficient generation of isolated sub-100 as XUV pulses from solid-state sources.
Space-Curved Resonant Line Solitons in a Generalized(2 + 1)-Dimensional Fifth-Order KdV System

On the basis of N-soliton solutions, space-curved resonant line solitons are derived via a new constraint proposed here, for a generalized(2+1)-dimensional fifth-order KdV system.The dynamic properties of these new resonant line solitons are studied in detail.We then discuss the interaction between a resonance line soliton and a lump wave in greater detail.Our results highlight the distinctions between the generalized(2+1)-dimensional fifth-order KdV system and the classical type.
iLBE for Computational Identification of Linear B-cell Epitopes by Integrating Sequence and Evolutionary Features

Linear B-cell epitopes are critically important for immunological applications, such as vaccine design, immunodiagnostic test, and antibody production, as well as disease diagnosis and therapy. The accurate identification of linear B-cell epitopes remains challenging despite several decades of research. In this work, we have developed a novel predictor, Identification of Linear B-cell Epitope(iLBE), by integrating evolutionary and sequence-based features. The successive feature vectors were optimized by a Wilcoxon-rank sum test. Then the random forest(RF)algorithm using the optimal consecutive feature vectors was applied to predict linear B-cell epitopes. We combined the RF scores by the logistic regression to enhance the prediction accuracy. iLBE yielded an area under curve score of 0.809 on the training dataset and outperformed other prediction models on a comprehensive independent dataset. iLBE is a powerful computational tool to identify the linear B-cell epitopes and would help to develop penetrating diagnostic tests. A web application with curated datasets for iLBE is freely accessible at http://kurata14.bio.kyutech.ac.jp/iLBE/.
Antidiabetic Effects of Gegen Qinlian Decoction via the Gut Microbiota Are Attributable to Its Key Ingredient Berberine

Gegen Qinlian Decoction(GQD), a traditional Chinese medicine(TCM)formula, has long been used for the treatment of common metabolic diseases, including type 2 diabetes mellitus. However, the main limitation of its wider application is ingredient complexity of this formula. Thus, it is critically important to identify the major active ingredients of GQD and to illustrate mechanisms underlying its action. Here, we compared the effects of GQD and berberine, a hypothetical key active pharmaceutical ingredient of GQD, on a diabetic rat model by comprehensive analyses of gut microbiota, short-chain fatty acids, proinflammatory cytokines, and ileum transcriptomics. Our results show that berberine and GQD had similar effects on lowering blood glucose levels, modulating gut microbiota, inducing ileal gene expression, as well as relieving systemic and local inflammation. As expected, both berberine and GQD treatment significantly altered the overall gut microbiota structure and enriched many butyrate-producing bacteria, including Faecalibacterium and Roseburia, thereby attenuating intestinal inflammation and lowering glucose. Levels of short-chain fatty acids in rat feces were also significantly elevated after treatment with berberine or GQD. Moreover, concentration of serum proinflammatory cytokines and expression of immune-related genes, including Nflcb1, Stat1, and Ifnrg1, in pancreatic islets were significantly reduced after treatment. Our study demonstrates that the main effects of GQD can be attributed to berberine via modulating gut microbiota. The strategy employed would facilitate further standardization and widespread application of TCM in many diseases.
考虑多源互补特性的微电网系统自动优化策略研究

微电网系统中功率供需不平衡将导致系统电压的不稳定,为此在考虑多源互补特性的基础上研究了一种新的微电网系统自动优化策略。通过光伏、水电、复合储能等多种发电系统建立微电网拓扑结构,以能量控制层、中央协调控制层和本地控制层设计微电网控制框架,采用复合储能实现微电源的协调控制,从而提高电压的稳定性;通过复合储能系统组成的调控系统,基于直流母线电压分区策略,实现系统自动优化控制。实验结果表明,研究的考虑多源互补特性的微电网系统自动优化策略能够有效实现功率平衡,确保电压稳定性。
基于多传感技术的发电机振动位移自动化测量系统设计

针对传统发电机振动位移测量系统测量结果精确度较低的问题,研究提出了一种基于多传感技术的发电机振动位移自动化测量系统。利用CPU、激光传感器与振动速度传感器、显示器组建系统硬件结构,然后设计振动位移自动化测量模块和波形显示模块组建系统软件部分。为了验证该系统测量结果的精确度,将其与3种传统测量系统进行对比实验,其测量结果精确度分别为86.4%、72.3%、66.8%、54.3%。通过比较可知,系统的测量结果精确度更高,验证了该自动化测量系统的优越性。
应用GRADE系统对针刺治疗膝骨关节炎系统评价的再评价

目的评价针刺治疗膝骨关节炎的系统评价方法学质量及证据质量。方法对知网、万方、维普、CBM、Embase、PubMed、Cochrane Library和Web of science 8个数据库进行检索,收集从建库至2020年10月30日有关针刺治疗KOA的系统评价。分别使用AMSTAR2量表对纳入文献进行方法学评价和GRADE系统进行证据质量等级评价。结果一共纳入22篇系统评价。AMSTAR2评价结果显示方法学质量均为极低级,。GRADE证据结果显示,74个结局指标,7个为中级,26个为低级,其余均为极低级。当前证据显示针刺治疗KOA有效,但由于方法学质量较低,需进一步验证。结论针刺治疗KOA的系统评价方法学质量和证据质量较低,应提高相关研究的规范性,为临床提供更高质量的证据。
一种金钱草掺伪品的鉴别检验研究

目的鉴别金钱草中掺伪品,为金钱草的质量控制提供依据。方法将供试品进行酸水解后,用HPLC法检定。结果对比掺伪的供试品水解后均产生两个特征峰,可以此为鉴别是否掺伪的依据。结论该法可准确的检出此种掺伪品。
炒诃子肉质量评价体系及抗衰老活性研究

目的制备炒诃子肉样品,采用HPLC对指标性成分没食子酸、鞣花酸、食子酸进行了含量测定,结合主成分分析和正交偏最小二乘法判别分析对炒诃子肉进行全面科学的质量评价。方法安捷伦ZORBAX SB-Aq C_(18)色谱柱(4.6 mm × 250 mm,5 μm);流动相为0.1%磷酸水-甲醇,梯度洗脱,流速1 mL·min~(-1),柱温35℃,检测波长270 nm,进样量20 μl,测定没食子酸、食子酸、鞣花酸的含量,制定全面科学的炒诃子肉的质量标准。将实验动物随机分为正常对照组、衰老模型组、炒诃子肉低(125mg/kg)、中(250mg/kg)、高(500mg/kg)剂量组。给药30天后,测定衰老小鼠血清中谷胱甘肽过氧化物酶(GSH-Px)、超氧化物歧化酶(SOD)和过氧化氢酶(CAT)活力、丙二醛(MDA)含量。结果主成分分析和正交偏最小二乘法判别分析显示广西产诃子与其他产地诃子得分分布于两个区域,可以被分为两类,提示广西产诃子与其他产地诃子在化学成分的量上存在一定的差异性。药理结果显示,与正常对照组相比,衰老模型组GSH-Px、CAT、SOD活力均明显降低,MDA含量明显升高(P <0.01) 。与衰老模型组相比,炒诃子肉水提物各剂量组GSH-PX、CAT、SOD活力均明显升高,MDA含量均明显下降。组织切片显示,与CHZR-LG组和CHZR-MG组相比,CHZR-HG组对小鼠肝、脑损伤保护作用最佳。结论通过对炒诃子肉3种指标性成分含量测定,结合主成分分析和正交偏最小二乘法判别分析,对炒诃子肉进行了全面科学的质量评价,炒诃子肉水提物对小鼠氧化应激损伤具有保护作用。
获得性反应性穿通性胶原病1例

反应性穿通性胶原病(reactive perforating collagenosis, RPC)是临床较少见的以变性胶原被排出体外为特征的穿通性皮肤病,其病因和发病机制尚不明确。儿童期发病与常染色体显性遗传或隐性遗传有关。成年发病常伴有高血压、糖尿病及肾功能衰竭等一种或多种系统性疾病,称获得性反应性穿通性胶原病(acquired reactive perforating collagenosis, ARPC)。现将我科诊治的1例冠状动脉粥样硬化性心脏病、2型糖尿病和高脂血症并发获得性反应性穿通性胶原病报告如下,并就相关文献进行复习。
小儿推拿联合脐灸治疗小儿脾虚质30例

脾虚质以形体偏瘦或虚胖、胃纳欠佳、易腹胀腹泻、大便不调、易感冒等症状为主要临床表现,是儿童常见的一种体质状态[1]。小儿亚健康的流行病学调查[2]显示,脾虚质位居小儿偏颇体质第一位,占43.75%。脾虚易生痰湿,痰湿内蕴易诱发呼吸系统疾病如哮喘、咳嗽等;脾虚运化功能受限,易乳食积滞,积滞内停,迁延不愈导致营养不良。中医外治疗法调理体质优势明显,如耳穴贴压、脐灸、中药穴位贴敷等具有良好的临床疗效[3-5],安全、无痛,易于被患儿及家长接受。笔者应用推拿联合脐灸治疗小儿脾虚质30例,现报道如下。
Carbon biomass,carbon-to-chlorophyll a ratio and the growth rate of phytoplankton in Jiaozhou Bay,China

Carbon biomass,carbon-to-chlorophyll a ratio (C:Chl a),and the growth rate of phytoplankton cells were studied during four seasonal cruises in 2017 and 2018 in Jiaozhou Bay,China.Water samples were collected from 12 stations,and phytoplankton carbon biomass (phyto-C) was estimated from microscopemeasured cell volumes.The phyto-C ranged from 5.05 to 78.52 μg C/L in the bay,and it constituted a mean of 38.16% of the total particulate organic carbon in the bay.High phyto-C values appeared mostly in the northern or northeastern bay.Diatom carbon was predominant during all four cruises.Dinoflagellate carbon contributed much less (<30%) to the total phyto-C,and high values appeared often in the outer bay.The C:Chl a of phytoplankton cells varied from 11.50 to 61.45 (mean 31.66),and high values appeared in the outer bay during all four seasons.The phyto-C was also used to calculate the intrinsic growth rates of phytoplankton cells in the bay,and phytoplankton growth rates ranged from 0.56 to 1.96/d;the rate was highest in summer (mean 1.79/d),followed by that in fall (mean 1.24/d) and spring (mean 1.17/d),and the rate was lowest in winter (mean 0.77/d).Temperature and silicate concentration were found to be the determining factors of phytoplankton growth rates in the bay.To our knowledge,this study is the first report on phytoplankton carbon biomass and C:Chl a based on water samples in Jiaozhou Bay,and it will provide useful information for studies on carbon-based food web calculations and carbon-based ecosystem models in the bay.
Bitter receptor TAS2R138 facilitates lipid droplet degradation in neutrophils during Pseudomonas aeruginosa infection

Bitter receptors function primarily in sensing taste, but may also have other functions, such as detecting pathogenic organisms due to their agile response to foreign objects. The mouse taste receptor type-2 member 138 (TAS2R138) is a member of the G-proteincoupled bitter receptor family, which is not only found in the tongue and nasal cavity, but also widely distributed in other organs, such as the respiratory tract, gut, and lungs. Despite its diverse functions, the role of TAS2R138 in host defense against bacterial infection is largely unknown. Here, we show that TAS2R138 facilitates the degradation of lipid droplets (LDs) in neutrophils during Pseudomonas aeruginosa infection through competitive binding with PPARG (peroxisome proliferator-activated receptor gamma) antagonist: N-(3-oxododecanoyl)-L-homoserine lactone (AHL-12), which coincidently is a virulence-bound signal produced by this bacterium (P. aeruginosa). The released PPARG then migrates from nuclei to the cytoplasm to accelerate the degradation of LDs by binding PLIN2 (perilipin-2). Subsequently, the TAS2R138-AHL-12 complex targets LDs to augment their degradation, and thereby facilitating the clearance of AHL-12 in neutrophils to maintain homeostasis in the local environment. These findings reveal a crucial role for TAS2R138 in neutrophil-mediated host immunity against P. aeruginosa infection.