mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Effect of scanning speed during PTA remelting treatment on the microstructure and wear resistance of nodular cast iron

The surface of nodular cast iron (NCI) with a ferrite substrate was rapidly remelted and solidified by plasma transferred arc (PTA) to induce a chilled structure with high hardness and favorable wear resistance. The effect of scanning speed on the microstructure, micro-hardness distribution, and wear properties of PTA-remelted specimens was systematically investigated. Microstructural characterization in-dicated that the PTA remelting treatment could dissolve most graphite nodules and that the crystallized primary austenite dendrites were transformed into cementite, martensite, an interdendritic network of ledeburite eutectic, and certain residual austenite during rapid solidifica-tion. The dimensions of the remelted zone and its dendrites increase with decreased scanning speed. The microhardness of the remelted zone varied in the range of 650 HV_(0.2) to 820 HV_(0.2), which is approximately 2.3-3.1 times higher than the hardness of the substrate. The wear re-sistance of NCI was also significantly improved after the PTA remelting treatment.
Study on precipitation and transition mechanisms from the magnetic properties of silicon steel during annealing

Precipitates play an important role in determining the mechanical and magnetic properties of silicon steel. This paper aims to in-vestigate the growth kinetics of precipitates in commercial silicon steel by analyzing its magnetic properties during isothermal annealing at 200°C. The growth of precipitates was studied by optical microscopy, scanning electron microscopy, transmission electron microscopy, and magnetic measurements. In combination with the coercive field and initial susceptibility, this technique offers the advantage of being non-destructive and providing quantitative information about the number, mean radius of precipitates, and fraction of transformation. An ob-served decrease in the number of precipitated particles indicates that the transformation starts from particles of appreciable initial size.
3'-UTR sequence of Macrobrachium rosenbergii extra small virus (XSV) is important for viral RNA packaging

The packaging of viral genomic RNA into virus particles is a critical step for virus maturation. This step includes the recognition and interaction between the nucleocapsid protein and viral RNA. The necessity of viral RNA packaging signals has been described for many RNA viruses (Cologna R, et al., 2000; Narayanan K, et al., 2001; Tchatalbachev S, et al., 2001). Occasional packaging of nongenomic viral RNAs and cellular RNAs results in noninfectious virions, and casual packaging of cellular RNA into viral particles would overwhelm the ability of viral genomic RNA to contact limited assembly factors. Therefore, viruses have probably developed a defensive strategy for the specific packaging of genomic RNA into virus particles. The packaging signals of some RNA viruses are located within more than one viral genomic region (Luytjes W, et al., 1989; Pattnaik A K, et al., 1995; Wei N, et al., 1990). For many viruses, it is unknown whether a single region or a combination of multiple genomic regions is necessary for viral RNA packaging.
Pithovirus: a new giant DNA virus found from more than 30,000-year-old sample

A third type of giant DNA virus named Pithovirus was recently isolated from a >30,000-year-old permafrost sample in Siberia (Legendre M, et al, 2014). Pithovirus has a larger pandoravirus-like particle with 1.5 μm length and its adenine-thymine-rich genome is about 600 kb, which is surprisingly smaller than Pandoravirus. There is very slight genetic relationship between Pithovirus and Pandoravirus and their replication cycles significantly differ. The groundbreaking discovery of this ancient virus expands our understanding of giant DNA viruses and raises the concern of pathogen reemergence from permafrost regions because of the change of climate or the activity of human.
The VP2 protein of grass carp reovirus (GCRV) expressed in a baculovirus exhibits RNA polymerase activity

The double-shelled grass carp reovirus (GCRV) is capable of endogenous RNA transcription and processing. Genome sequence analysis has revealed that the protein VP2, encoded by gene segment 2 (S2), is the putative RNA-dependent RNA polymerase (RdRp). In previous work, we have ex-pressed the functional region of VP2 that is associated with RNA polymerase activity (denoted as rVP~(2390-900)) in E. coli and have prepared a polyclonal antibody against VP2. To characterize the GCRV RNA polymerase, a recombinant full-length VP2 (rVP2) was first constructed and expressed in a baculovirus system, as a fusion protein with an attached His-tag. Immunofluorescence (IF) assays, together with immunoblot (IB) analyses from both expressed cell extracts and purified Histagged rVP2, showed that rVP2 was successfully expressed in Sf9 cells. Further characterization of the replicase activity showed that purified rVP2 and GCRV particles exhibited poly(C)-dependent poly(G) polymerase activity. The RNA enzymatic activity required the divalent cation Mg~(2+), and was optimal at 28 °C. The results provide a foundation for further studies on the RNA polymerases of aquareoviruses during viral transcription and replication.
Vasopressin decreases neuronal apoptosis during cardiopulmonar y resuscitation

The American Heart Association and the European Resuscitation Council recently recommend-ed that vasopressin can be used for cardiopulmonary resuscitation, instead of epinephrine. However, the guidelines do not discuss the effects of vasopressin during cerebral resuscitation. In this study, we intraperitoneally injected epinephrine and/or vasopressin during cardiopul-monary resuscitation in a rat model of asphyxial cardiac arrest. The results demonstrated that, compared with epinephrine alone, the pathological damage to nerve cells was lessened, and the levels of c-Jun N-terminal kinase and p38 expression were signiifcantly decreased in the hippo-campus after treatment with vasopressin alone or the vasopressin and epinephrine combination. No signiifcant difference in resuscitation effects was detected between vasopressin alone and the vasopressin and epinephrine combination. These results suggest that vasopressin alone or the vasopressin and epinephrine combination suppress the activation of mitogen-activated protein kinase and c-Jun N-terminal kinase signaling pathways and reduce neuronal apoptosis during cardiopulmonary resuscitation.
Pro-urokinase promotes angiogenesis but does not reduce neuronal apoptosis in infarcted cerebral tissue

Ischemic stroke is most commonly caused by vascular occlusion due to thrombosis or arterial embolism. Recently, thrombolysis has been used with increasing frequency for the treatment of acute ischemic stroke. Among the drugs used for thrombolysis, only recombinant tissue plasminogen activator is widely accepted internationally (Albers et al., 2008). In China, urokinase has been widely used for thrombolysis after acute ischemic stroke. Pro-urokinase is the precursor of urokinase. Compared with urokinase, pro-urokinase has greater ability to dissolve thrombus and is safer to use. A previous study found that the recanalization rate was significantly higher after arterial thrombolysis with pro-urokinase than with recombinant tissue plasminogen activator (Fischer et al., 2005). This study compared the thrombolytic effects of pro-urokinase, recombinant tissue plasminogen activator, and urokinase in a dog model of acute cerebral embolism.
建设生态文明保护地下水资源促进可持续开发利用(代序)

水,是人类赖以生存与发展的重要资源。在我国多年平均的年水资源总量2.8万亿立方米中,地下水资源量约占8千亿立方米。但是,我国有70%的城镇的人民生活用水是依靠地下水。而我国人均水资源目前已不足2100 m3/(人·年),距离联合国规定的缺水标准1700 m3/(人·年),为缺水的标准,已是为期不远了。北方干旱区及南北方大都市,人均当地水资源只有一百多至几百立方米/(人·年),都是缺水的地区与都市。
世界最高大的凤梨科植物--安第斯皇后(Puya raimondii Harms)

安第斯皇后(Queen of the Andes)为凤梨科(Bromeliaceae)普亚凤梨属(Puya)植物,学名为Puya raimondii Harms,也称为南美高原皇后(Queen of the puna)。在原产地,虽然有不同的地方名,但通常称为“Titanca”。普亚凤梨属植物原产南美洲的安第斯山区及中美洲南部,该属大多数种类终生只开一次花,开花后植株死亡。“Puya”的名字来源于马普切印第安语,意为“点(point)”。
云南铅锌矿中的天然放射性

通过监测资料,补充开展现场采样与实验室~(238)U、~(232)Th、~(226)Ra分析,了解云南铅锌矿中的天然放射性水平,防治辐射环境污染,为云南伴生矿开发利用及行政监管提供科学依据。结果表明,云南铅锌矿原矿中天然放射性U系含量明显高于Th系,铅锌矿中天然放射性核素比活度波动范围较大,其整体水平不高,尚未发现达到审管要求的伴生放射性铅锌矿。
天际线扫描: 环境与生物多样性保护研究的新方法

环境问题迫切需要开展未来学研究, 许多过去看来是边际的问题已经成为政府议事日程中主要的问题, 例如全球变化、恐怖主义等, 能源、食物和水资源安全以及由于生物多样性丧失而导致的生态系统服务功能丧失很快将成为下一批类似的问题(Sutherland et al., 2009)。针对英国制定未来保护政策和环境问题决策的迫切需要, 剑桥大学保护生物学教授Sutherland等(2008)提出了对环境与生物多样性保护问题应用的未来学研究方法, 即天际线扫描(Horizon Scanning)研究, 也称为地平线扫描。Sutherland等(2009)强调在全球尺度上开展天际线扫描的必要性。通过专家系统检索, 天际线扫描方法能够发现环境与生物多样性保护领域目前未被足够认知的、中长期的、未来的潜在威胁与机遇。提早发现未来环境与生物多样性保护问题将会降低未来突然面临社会或环境变化后果的可能性, 有助于提高环境意识, 实现环境问题预警, 为相应的科学、技术和政策创新提供动力。从2009年开始, Sutherland等(2010, 2011, 2012, 2013, 2014)已连续5年开展了年度全球环境保护的天际线扫描, 并每年在Trends in Ecology and Evolution这一国际知名刊物上发表相关结果, 说明这一研究的重要性。
树突状细胞在诱导调节性T细胞中的作用

树突状细胞(Dendritic ells,DCs)是一种专职的抗原提呈细胞,体内含量少,提呈作用超强。DCs 能激活初始T细胞诱导机体的有效免疫应答,并决定免疫应答的方向,同时DCs 在维持免疫耐受方面也具有重要作用[1]。调节性T细胞(Regulatory T cells,Tregs)具有免疫抑制功能,是诱导非自身及外来抗原产生外周耐受的关键调节性细胞,包括天然发生的调节性T细胞(natural regulatory T cell,nTreg)和外周诱导性调节性T细胞(adaptive regulatory T cell,aTreg)。前者来源于胸腺,除表达CD4、CD25外,还表达转录因子叉头状/翅膀装螺旋转录因子(fork-head box P3,Foxp3); 后者是以T细胞受到特异性抗原刺激后由细胞因子诱导产生。近年来许多研究结果证实DCs 除在中枢耐受中具有重要作用外,在外周耐受中也有显著作用。DCs 通过诱导效应性T细胞的无反应诱导Treg的分化,并以此调节自身抗原的外周耐受。本文主要对DCs 在诱导 Treg 分化中的作用进行简要论述。
呼吸作用对延胡索生长状况的影响

目的:探索呼吸作用对延胡索生长及块茎形成的影响。方法:在不同时期测定延胡索野生品与栽培品及其不同生长部位的呼吸速率。结果:野生品与栽培品的地下块茎在不同时期的呼吸速率符合一般规律,3月份栽培品与野生品有显著差异;由地下茎产生的新生块茎的呼吸速率比较高;地上部分呼吸速率2月份最高,3月份最低。结论:块茎的物质积累主要在3月份完成;在4月份收获时需减少呼吸作用的消耗。
高通量血液透析对尿毒症患者甲状旁腺激素和微炎症状态的影响

慢性肾衰竭(CRF)患者体内甲状旁腺激素(PTH)潴留是导致皮肤瘙痒、肾性骨病、血管钙化及心肌损害等并发症的重要原因。透析患者的微炎症状态亦是导致患者发生心血管事件和病死率增高的重要原因。血液透析(HD)对清除小分子毒素如尿素氮(BUN)、肌酐(Cr)等的效果较好,而对中大分子毒素如PTH、β_2-微球蛋白(β_2-MG)等清除效果差。如何增加尿毒症患者体内PTH等的清除,改善体内微炎症状态?本研究采用前瞻性自身对照研究方法,观察高通量血液透析(HFHD)治疗后尿毒症患者体内超敏C-反应蛋白(hs-CRP)及PTH浓度的变化。
非棘阿米巴角膜炎伴角膜神经周围炎一例

棘阿米巴是广泛存在于土壤、水源以及上呼吸道的非寄生原虫。有滋养体(活跃)和包囊(静止)两种存在形式。AK是一种顽固的、致盲性的角膜感染性疾病。发生的3大危险因素包括配戴角膜接触镜、接触污染的水源和角膜外伤。95%的AK患者存在以上至少一种危险因素,85%的AK患者有配戴角膜接触镜史。本例患者无上述危险因素。AK早期表现为畏光、流泪和疼痛,且剧烈疼痛可与病变程度不成比例。本例患者有眼痛,但程度较轻,主要表现为畏光、流泪。AK早期临床体征包括:假树枝样上皮损害、角巩膜缘炎、伴随角膜知觉减退的轻度前葡萄膜炎和角膜神经周围炎,即放射状角膜神经炎(radial keratoneuritis,RK),表现为由角膜缘向角膜中央方向,沿角膜神经走行的放射状细胞浸润,相应的角膜上皮保持完整。目前,引起RK的原因并不确切,有体外研究显示棘阿米巴滋养体对神经细胞具有强烈的趋化作用,推测滋养体沿神经走行相对于其他迁徙方向更容易,并对局部神经造成损害。同时,RK被认为是AK的特征性改变,这也是本病例被高度怀疑为AK的主要原因。有报道指出,RK并非AK特征性表现,假单胞菌角膜炎亦可有RK表现。另外,RK也并非出现于所有AK病例。Sun等总结AK患者20例,RK表现2例,占10%。Bernauer等总结AK患者70例,RK表现者5例,占7%。Bacon等总结72例77眼AK,RK表现9例,占13%。随着病灶的扩大和炎症的发展,在AK的中期可形成中心或旁中心的角膜基质的环形浸润或溃疡,此为AK的另一典型临床表现。本例患者就诊时已有2个月病史,角膜旁中心基质层浸润和混浊应引起重视。晚期AK角膜基质混浊、溶解可伴有前房积脓。本病例角膜刮片镜检未见病原体,但患者病史较长,已应用大量抗生素滴眼液影响镜检率,因此不能完全排除细菌性角膜炎诊断。龟分支杆菌是引起非结核分枝杆菌性角膜炎中最常见的一种条件致病菌,临床罕见。在细菌感染中,龟分支杆菌性角膜炎亦可表现为放射状角膜炎,通常有明确的眼部手术、外伤、角膜接触镜配戴史,糖皮质激素治疗症状加重,病程迁延。角膜浸润灶呈单一或多灶边界清楚的点状、圆形或放射状、羽毛状的灰蓝色或灰白色浸润,后弹力层放射状改变,灰白色糊状角膜后沉积物,前房积脓。本例患者发病前有大量饮酒史,无异物及外伤史;无灰白色浸润病灶等表现,糖皮质激素治疗有效,结合其角膜表现,可排除细菌及真菌感染的诊断。无角膜接触镜配戴史及外伤史,眼痛程度为轻度,无明显分泌物,无明显上皮缺损或基质层溃疡,糖皮质激素治疗有效,虽有RK 表现,但可排除AK诊断,考虑与病毒感染引起的免疫反应有关。病毒可长期潜伏在人体组织内,当病毒与人体免疫力处于相对平衡状态时,不引起症状;机体在某些诱因,如感冒、发热、创伤、手术、月经、紫外线照射等的作用下,免疫功能下降,潜伏在机体内的病毒可重新繁殖从而引起症状。本例患者既往体健,发病前较大量、频繁饮酒及劳累史,并伴有患侧眼痛、头痛,分析病因与病毒感染致角膜基质的免疫炎症反应有关。检索文献尚未见病毒性角膜炎伴角膜神经周围炎的报道,本例患者可能为角膜神经周围炎,可为放射状角膜神经炎的病因分析及鉴别诊断提供新的思路。
Spin-resolved self-doping tunes the intrinsic halfmetallicity of AlN nanoribbons

We present a first-principles theoretical study of electric field- and straincontrolled intrinsic half-metallic properties of zigzagged aluminium nitride (AlN) nanoribbons. We show that the half-metallic property of AlN ribbons can undergo a transition into fully-metallic or semiconducting behavior with application of an electric field or uniaxial strain. An external transverse electric field induces a full charge screening that renders the material semiconducting. In contrast, as uniaxial strain varies from compressive to tensile, a spin-resolved selective self-doping increases the half-metallic character of the ribbons. The relevant strain-induced changes in electronic properties arise from band structure modifications at the Fermi level as a consequence of a spin-polarized charge transfer between p-orbitals of the N and Al edge atoms in a spin-resolved self-doping process. This band structure tunability indicates the possibility of designing magnetic nanoribbons with tunable electronic structure by deriving edge states from elements with sufficiently different localization properties. Finite temperature molecular dynamics reveal a thermally stable half-metallic nanoribbon up to room temperature.
Evolutionary consequences of deception: Complexity and informational content of colony signature are favored by social parasitism

Nestmate recognition codes show remarkable chemical complexity, involving multiple biochemical pathways. This complexity provides the opportunity to evaluate the ecological and social conditions that favor the evolution of complex signaling. We investigated how the chemical signatures of three populations of the social paper wasp Polistes biglumis differed in terms of concentration of hydrocarbons, proportions of branched hydrocarbons and overall variation. We tested whether the variation in chemical signatures among populations could be explained by the prevalence of social parasites or whether this was just an effect of local abiotic conditions which influenced the composition of the hydrocarbon cuticular layer. We studied the chemical signature in three populations in which obligate social parasites differed in the selection pressures they imposed on host populations. Within each population, we restricted our analyses to non-parasitized hosts, to avoid potential short-term effects of parasite presence on the host chemical signatures. We found that host colonies in parasitized populations had more diverse profiles than the parasite-free population. Moreover, the overall concentration of hydrocarbons and the relative proportion of branched hydrocarbons were larger in the parasitized populations, relative to the non-parasitized one. This is to our knowledge the first evidence in favour of the hypothesis that different traits in the host chemical signatures as a whole undergo evolutionary changes resulting from directional or balancing selection imposed by social parasites. We conclude that obligate social parasites act as 'engines of diversity' on host chemical signatures and operate in favor of a geographic mosaic of diverging communication codes.
UV reflectance but no evidence for colour mimicry in a putative brood-deceptive orchid Corybas cheesemanii

Rewardless orchids attract pollinators by food, sexual, and brood-site mimicry, but other forms of sensory deception may also operate. Helmet orchids (Corybas, Nematoceras and related genera) are often assumed to be brood-site deceivers that mimic the colours and scents of mushrooms to fool female fungus gnats (Mycetophilidae) into attempting oviposition and pollinating flowers. We sampled spectral reflectances and volatile odours of an endemic terrestrial New Zealand orchid Corybas cheesemanii, and co-occurring wild mushrooms. The orchid is scentless to humans and SPME GC-MS analyses did not detect any odours, but more sensitive methods may be required. The orchids reflected strongly across all visible wavelengths (300-700nm) with peaks in the UV (~320nm), yellow-green (500-600 nm) and red regions (650-700 nm), whereas mushrooms and surrounding leaf litter reflected predominantly red and no UV. Rather than mimicking mushrooms, these orchids may attract pollinators by exploiting insects' strong sensory bias for UV. Modelling spectral reflectances into a categorical fly vision model and a generic tetrachromat vision model provided very different results, but neither suggest any mimicry of mushrooms. However, these models require further assessment and data on fly spectral sensitivity to red wavelengths is lacking – a problem given the predominance of red, fly-pollinated flowers worldwide.
Epigallocatechin-3-gallate induces apoptosis, inhibits proliferation and decreases invasion of glioma cell

Epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea, has been considered a potential therapeutic and chemopreventive agent for cancer. Glioma is a malignant tumor with high mortality but effective therapy has not yet been developed. In this study, we found that EGCG induced apoptosis in U251 glioma cells via the laminin receptor (molecular weight 67kDa) in a time- and dose-dependent manner, decreased their invasiveness and inhibited their proliferation. The mitogen-activated protein kinase pathway was shown to be involved in glioma cell apoptosis and proliferation. Furthermore, the mRNA levels of matrix metalloproteinase (MMP)-2 and MMP-9 were reduced after EGCG treatment. These results suggest that EGCG has important therapeutic effects with low toxicity and side-effects, and could be used in cancer chemoprevention.
Identification, occurrence, and validation of DRE and ABRE Cis-regulatory motifs in the promoter regions of genes of Arabidopsis thaliana

Plants posses a complex co-regulatory network which helps them to elicit a response under diverse adverse conditions. We used an in silico approach to identify the genes with both DRE and ABRE motifs in their promoter regions in Arabidopsis thaliana. Our results showed that Arabidopsis contains a set of 2,052 genes with ABRE and DRE motifs in their promoter regions. Approximately 72% or more of the total predicted 2,052 genes had a gap distance of less than 400 bp between DRE and ABRE motifs. For positional orientation of the DRE and ABRE motifs, we found that the DR form (one in direct and the other one in reverse orientation) was more prevalent than other forms. These predicted 2,052 genes include 155 transcription factors. Using microarray data from The Arabidopsis Information Resource (TAIR) database, we present 44 transcription factors out of 155 which are upregulated by more than twofold in response to osmotic stress and ABA treatment. Fifty-one transcripts from the one predicted above were validated using semiquantitative expression analysis to support the microarray data in TAIR. Taken together, we report a set of genes containing both DRE and ABRE motifs in their promoter regions in A. thaliana, which can be useful to understand the role of ABA under osmotic stress condition.
The rice OsV4 encoding a novel pentatricopeptide repeat protein is required for chloroplast development during the early leaf stage under cold stress

Pentatricopeptide repeat (PPR) proteins, characterized by tandem arrays of a 35 amino acid motif, have been suggested to play central and broad roles in modulating the expression of organelle genes in plants. However, the molecular mechanisms of most rice PPR genes remains unclear. In this paper, we isolated and characterized a temperature-conditional virescent mutant, OsV4, in rice (Oryza sativa cultivar Jiahua1 (WT, japonica rice variety)). The mutant displays albino phenotype and abnormal chloroplasts at the three leaf stage, which gradually turns green after the four leaf stage at a low temperature (20 °C). But the mutant always develops green leaves and well-developed chloroplasts at a high temperature (32 °C). Genetic and molecular analyses uncovered that OsV4 encodes a novel chloroplast-targeted PPR protein including four PPR motifs. Further investigations show that the mutant phenotype is associated with changes in chlorophyll content and chloroplast development. The OsV4 transcripts only accumulate to high levels in young leaves, indicating that its expression is tissue-specific. In addition, transcript levels of some ribosomal components and plastidencoded polymerase-dependent genes are dramatically reduced in the albino mutants grown at 20 °C. These findings suggest that OsV4 plays an important role during early chloroplast development under cold stress in rice.
Self-processing of ribozyme-flanked RNAs into guide RNAs in vitro and in vivo for CRISPR-mediated genome editing

CRISPR/Cas9 uses a guide RNA (gRNA)molecule to execute sequence-specific DNA cleavage and it has been widely used for genome editing in many organisms. Modifications at either end of the gRNAs often render Cas9/gRNA inactive. So far, production of gRNA in vivo has only been achieved by using the U6 and U3 snRNA promoters. However, the U6 and U3 promoters have major limitations such as a lack of cell specificity and unsuitability for in vitro transcription. Here, we present a versatile method for efficiently producing gRNAs both in vitro and in vivo. We design an artificial gene named RGR that, once transcribed, generates an RNA molecule with ribozyme sequences at both ends of the designed gRNA. We show that the primary transcripts of RGR undergo self-catalyzed cleavage to generate the desired gRNA, which can efficiently guide sequence-specific cleavage of DNA targets both in vitro and in yeast. RGR can be transcribed from any promoters and thus allows for cell- and tissue-specific genome editing if appropriate promoters are chosen. Detecting mutations generated by CRISPR is often achieved by enzyme digestions, which are not very compatible with high-throughput analysis. Our system allows for the use of universal primers to produce any gRNAs in vitro, which can then be used with Cas9 protein to detect mutations caused by the gRNAs/CRISPR. In conclusion, we provide a versatile method for generating targeted mutations in specific cells and tissues, and for efficiently detecting the mutations generated.
医疗保险支付方式改革的关键要素与现实路径

随着医疗改革(简称医改)的推进,中国医疗保险(简称医保)逐步实现了全覆盖、全统筹,开始进入了全民医保时代,医保资金收入日益成为医疗机构主要经费来源,也成为财政对医疗机构财政补偿的主要方式之一。由此,如何约束住医疗机构的不合理开支,使百姓的“救命钱”发挥最大效益,使医保制度保持可持续性,便成了进入全民医保时代后不得不思考的问题。当前,医保支付方式改革被认为是约束医疗机构、破除“以药补医”的一个重要切入点那么,如何认识这一改革在全民医保时代的重要地位?在医保支付方式的设计和改革中应注重哪些关键要素?本文对此进行了一些思考。
腹腔孤立性纤维瘤8例临床分析及文献复习

目的探讨腹腔孤立性纤维瘤(SFT)的临床表现、诊断及治疗方法。方法复习国内、外文献,回顾性分析该院2002年1月至2012年12月手术切除及行病理检查确诊为SFT患者的病例资料,就其来源、临床表现、诊断、治疗及其预后进行分析与总结。结果 SFT术前诊断困难,表现多为惰性生长的无痛性肿瘤,无特殊临床表现,肿块巨大累及邻近脏器时可出现相应的症状。2002年1月至2012年12月共确诊SFT患者8例,肿瘤位于腹腔右髂窝、盆腔、胃窦部等,临床表现不明显。8例患者均行手术完整切除肿瘤,术后经病理确诊为良性SFT 7例,恶性SFT 1例,8例患者随访6个月至9年,肿瘤无复发。结论超声、CT 检查对SFT无特异性,病理检查是其确诊的惟一方法,根治性切除是治疗本病的首选方法,是否切除彻底是影响预后的最重要因素。
HENIG GLOBALLY EFFICIENCY FOR SET-VALUED OPTIMIZATION AND VECTOR VARIATIONAL INEQUALITY

This paper deals with Henig globally efficiency in vector optimization involving generalized cone-preinvex set-valued mapping. Some properties of generalized cone-preinvex set-valued map are derived. It also disclose the closed relationships between Henig globally efficiency of generalized conepreinvex set-valued optimization problem and Henig globally efficiency of a kind of vector variational inequality.
FORECASTING TIME SERIES WITH GENETIC PROGRAMMING BASED ON LEAST SQUARE METHOD

Although time series are frequently nonlinear in reality, people tend to use linear models to fit them under some assumptions unnecessarily in accordance with the truth, which unsurprisingly leads to unsatisfactory performance. This paper proposes a forecast method: Genetic programming based on least square method (GP-LSM). Inheriting the advantages of genetic algorithm (GA), without relying on the particular distribution of the data, this method can improve the prediction accuracy because of its ability of fitting nonlinear models, and raise the convergence speed benefitting from the least square method (LSM). In order to verify the validity of this method, the authors compare this method with seasonal auto regression integrated moving average (SARIMA) and back propagation artificial neural networks (BP-ANN). The results of empirical analysis show that forecast accuracy and direction prediction accuracy of GP-LSM are obviously better than those of the others.
高职院校开设老年护理特色专业的探索

随着我国人口老龄化和养老产业的快速发展,老年护理专业人员以成为行业急需、社会紧缺的技能型人才。而人才的培养要依托相应专业的开拓和建设,我院是湖南省高等院校中最早开设老年护理专业的学校,2012年以来以"十二五"省级重点项目"老年护理特色专业"建设为契机,开展该专业的目标指向、机制创新、课程体系构建、师资建设的研究,探索我国高等职业教育开设老年护理特色专业的经验。
老年心功能不全患者58例综合护理干预

心功能不全患病率高,5年存活率与恶性肿瘤相仿。老年心功能不全是心肌梗死幸存患者数月至数年后的常见归属,预后差,花费巨大,本文旨在探讨老年心功能不全患者的综合护理干预。