mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Aqueous synthesis of CdSe and CdSe/CdS quantum dots with controllable introduction of Se and S sources

A new and convenient route is developed to synthesize CdSe and core-shell CdSe/CdS quantum dots(QDs) in aqueous solution.The gaseous precursors,H_2Se and H_2S,generated on-line by reducing SeO_3~(2-) with NaBH 4 and the reaction between Na_2 S and diluted H_2SO_4,are used to form high-quality CdSe and CdSe/CdS QDs,respectively.The synthesized water-soluble CdSe and CdSe/CdS QDs possess high quantum yield(3% and 20%) and narrow full-width-at-half-maximum(43 nm and 38 nm).The synthesis process is easily reproducible with simple apparatus and low-toxic chemicals,and can be readily extended to the large-scale aqueous synthesis of QDs.
An environmentally benign benzylic oxidation catalyzed by hypervalent iodine intermediate in water

An effective and environmentally benign benzylic oxidation for transition of alkylarenes into the corresponding carbonyl compounds was reported.Alkylarenes were mixed and stirred with potassium bromide,m-chloroperbenzoic acid and a catalytic amount of iodobenzene in water at 60 8C for several hours,a series of the corresponding carbonyl compounds was obtained in moderate to good yields.In the reaction,iodobenzene was first oxidized by m-chloroperbenzoic acid into the hypervalent iodine intermediate which then reacted with potassium bromide to form the key radical initiator for the benzylic oxidation.
美国药物治疗学课程群设计对我国培养临床药学人才的启示

目的探讨美国药学院药物治疗学(Pharmacotherapy,PT)课程群设计对我国临床药学人才培养的启示。方法介绍美国药学院PT课程群的目标、内容、评价方法及与其他课程的关系,并与我国PT课程进行对比分析。结果PT课程群为药学实践提供坚实的理论基础,是培养学生循证医学和个体化用药思维的关键,其设计体现了美国临床药学人才培养的思路,理念和模式。结论PT课程群的设计对我国培养合理用药人才有重要启示作用,并为我国药学院PT教学提供了可借鉴的方案。
应用足底内侧动脉皮瓣修复跟腱部皮肤缺损

目的回顾足底内侧动脉皮瓣修复跟腱部皮肤缺损的效果.方法2005年4月至2009年10月,应用足底内侧动脉皮瓣修复跟腱部皮肤缺损12例,皮瓣面积3cm×5cm~5cm×8cm,5例伴有跟腱部分损伤,术后随访观察皮瓣质地、感觉及足部功能.结果皮瓣全部成活11例,皮瓣边缘部分坏死1例.9例获得随访,平均5个月,皮瓣质地好,耐磨,触觉正常,两点辨别觉4~11mm,平均7mm,恢复正常功能.结论足底内侧动脉皮瓣足治疗跟腱部皮肤缺损的一种理想方法.
中国穿支皮瓣的名词术语与临床应用原则共识(暂定稿)

穿支皮瓣(perforatorflap)的概念起于20世纪80年代后期,至今已有20多年的历史.但前10余年并未引起广泛关注.据PubMed检索(2011年9月30日),共有与"perforatorflap"相关的论文1708篇,其中近5年(2007~2011年)有1076篇(占63%).这说明2003年穿支皮瓣Gentconsensus("根特"共识)的正式发表,极大地促进了穿支皮瓣的发展,学者们也才真正地认可与推广穿支皮瓣[1-30].
不同乙型肝炎病毒载量对慢性乙型肝炎患者红细胞系统的影响

大量资料显示，乙型肝炎（乙肝）患者中贫血发生率远高于普通人群，且存在缺铁性贫血、巨幼细胞性贫血，还有大量分类不明确的贫血。但目前鲜见有探讨HBV DNA对红细胞系统影响的报道。本研究旨在探讨不同HBV载量对乙肝患者红细胞系统各参数的影响。
肋外翻不是佝偻病体征

《中华儿科杂志》2011年11期814~817页刊出的“3例新生儿马兜铃酸肾病临床特点及长期随访分析”一文，临床资料“例1^^出现方颅、肋外翻等佝偻病的临床表现……”的表述有误。 《中华儿科杂志》编辑委员会、中华医学会儿科学分会儿童保健学组、全国佝偻病防治科研协作组制定的《维生素D缺乏性佝偻病防治建议》中描述佝偻病激期的临床表现：">6个月婴儿可见方颅、手（足）镯、肋串珠、肋软骨沟、鸡胸、0型腿、X型腿等体征”（请注意用词为“肋串珠”、“肋软骨沟”，没有提及肋外翻）。有关佝偻病体征的释义如下：
全身水肿性幼年皮肌炎一例

本例及其他文献报道的患者对激素治疗反应大都不敏感，相对于典型的JMD，此类患儿更需要全面、综合、长时间的治疗，包括大剂量静脉激素冲击，联合免疫抑制剂及其他免疫调节治疗，同时也应加强控制感染，防治药物的副反应，减轻各器官的累积损害。广泛水肿的皮肌炎患者病情较重，多预后不良，儿科医生应意识到全身广泛性水肿可以是儿童皮肌炎的特征。
射频消融术在双侧同时发生肾癌治疗中的应用

我们自2006年起开始应用射频消融术治疗肾脏肿瘤，其中7例双侧同时发生肾细胞癌，对肿瘤较大侧行根治性肾切除术，对其中不适合行肾部分切除术保肾治疗的患者采用射频消融的方法治疗，临床效果满意，报告如下。
鼻腔及面部鸟型胞内分枝杆菌感染一例

患者女,46岁.因鼻腔流脓血、发热(体温39℃以上),贫血伴面部疼痛性红色斑块和结节2年于2011年5月6日入院.入院前曾在某院行面部斑块活检,提示为"韦格纳肉芽肿",治疗后无好转.体检:面部散在黄豆至蚕豆大淡褐色瘢痕,为活检术后遗留,部分瘢痕区可触及皮下结节,压痛明显,头部CT示双侧上颌窦、蝶窦、筛窦及左侧鼻腔均被软组织填充,窦壁骨质无破坏.取面部结节组织及鼻腔内组织活检.
骨膜增生厚皮症合并白癜风一例

讨论骨膜增生厚皮症是以骨膜增厚、皮肤肥厚及回状头皮为主要表现的临床综合征，分为原发性和继发性两种。原发性骨膜增生厚皮症与常染色体显性遗传或与近亲结婚有关，常于儿时发病，青春期加重时就诊，进展5~10年后变为静止状态。本病主要临床表现为杵状指（趾）、皮肤增厚、脑回状头皮、对称性关节肿胀伴或不伴疼痛及功能障碍、皮脂分泌增多、多汗等。本病需与：①肢端肥大症鉴别，后者多有蝶鞍改变和内分泌检查异常，而无骨膜增生改变；②甲状腺性肢端肥大，发生于甲亢患者，除杵状指外有突眼、黏液性水肿表现， T3/T4升高为鉴别要点。本例患者合并节段型白癜风。
糙皮病二例

讨论糙皮病好发于夏秋季节，由于烟酸类维生素缺乏所致。临床上典型的症状为皮炎、腹泻和痴呆三联征。三者同时存在的临床病例较少见。我们的2例患者患病期间无明显的腹泻、记忆力减退、健忘、痴呆症状。就诊时回答问题清楚，患者日常经常参加田间劳动，临床表现以光暴露部位的手背、前臂、足背处的光敏性皮炎症状为主。临床上应与食用泥螺及某些植物引起的日光性皮炎鉴别。应努力提高基层医院医师对糙皮病的诊断和治疗水平。明确诊断、合理用药，在日常生活中补充适量的蛋白质、维生素，即可达到防病治病的目的。
Climate and Vegetation Drivers of Terrestrial Carbon Fluxes: A Global Data Synthesis

The terrestrial carbon (C) cycle plays an important role in global climate change, but the vegetation and environmental drivers of C fluxes are poorly understood. We established a global dataset with 1194 available data across site-years including gross primary productivity (GPP), ecosystem respiration (ER), net ecosystem productivity (NEP), and relevant environmental factors to investigate the variability in GPP, ER and NEP, as well as their covariability with climate and vegetation drivers. The results indicated that both GPP and ER increased exponentially with the increase in mean annual temperature (MAT) for all biomes. Besides MAT, annual precipitation (AP) had a strong correlation with GPP (or ER) for non-wetland biomes. Maximum leaf area index (LAI) was an important factor determining C fluxes for all biomes. The variations in both GPP and ER were also associated with variations in vegetation characteristics. The model including MAT, AP and LAI explained 53 %of the annual GPP variations and 48 %of the annual ER variations across all biomes. The model based on MAT and LAI explained 91 %of the annual GPP variations and 92.9 %of the annual ER variations for the wetland sites. The e ﬀ ects of LAI on GPP, ER or NEP highlighted that canopy-level measurement is critical for accurately estimating ecosystem–atmosphere exchange of carbon dioxide. The present study suggests a significance of the combined e ﬀ ects of climate and vegetation (e.g., LAI) drivers on C fluxes and shows that climate and LAI might influence C flux components di ﬀ erently in di ﬀ erent climate regions.
重度碱烧伤合并吸入性气道损伤患者的护理

总结1例重度碱烧伤合并吸入性气道损伤患者的护理经验。护理要点包括依托多学科团队实施专业性、针对性的创面有效引流;呼吸振荡排痰与无创物理咳痰仪交替及胸腔闭式引流联合应用,使创伤性湿肺分泌物有效引流,促进气道创面愈合及肺复张。患者经过20 d的精心治疗和护理,病情稳定后转入烧伤科继续治疗。
Sobolev Spaces on Quasi-Kahler Complex Varieties

If V is an irreducible quasi-Kahler complex variety and E is a vector bundle over reg(V),the author proves that W_0~(1,2) (reg(V),E) = W~(1,2)(reg(V),E),and that for dimC reg(V) >1,the natural inclusion W~(1,2)(reg(V),E) → L~2(reg(V),E) is compact,the natural inclusion W~(1,2)(reg(V),E)→ L~(2v/v–1) (reg(V),E) is continuous.
On Constacyclic Codes over Z_(p_1p_2···p_t)

Let t ≥ 2 be an integer,and let p_1,· · ·,p_t be distinct primes.By using algebraic properties,the present paper gives a sufficient and necessary condition for the existence of non-trivial self-orthogonal cyclic codes over the ring Z_(p_1p_2···p_t) and the corresponding explicit enumerating formula.And it proves that there does not exist any self-dual cyclic code over Z_(p_1p_2···p_t).
Diversity of the endophytic filamentous fungal leaf community at different development stages of eucalyptus

Fungal endophytic species inhabiting the leaves of eucalypts are capable of utilising leaf sugars and can influence both plant growth and health. Endophytic fungal symbionts can use simple soluble sugars in leaves as their main carbon source. This study set out to determine the diversity and distribution of the endophytic filamentous fungal leaf community in the hybrid Eucalyptus urograndis due to its economic importance. The fungal leaf community was characterised using denaturing gradient electrophoresis (DGGE) and correlated with levels of leaf nutrients and sugars throughout plant development. Sequencing of DGGE bands revealed the presence of Basidiomycota and Ascomycota phyla. Fourteen species and three genera of filamentous fungi were identified, and the population structure was affected by the plant developmental stage. Levels of K, Cu, N and Mn influenced communities from the clonal garden, whereas leaves in the field had higher glucose, fructose and sucrose. Many fungi were found to be specific to a certain development stages: Diplomitoporus crustulinus, Podosphaera tridactyla and Aspergillus restrictus to the clonal garden stage; Chaetomella acutiseta and Ascotricha chartarum to the shading stage; Erratomyces patelii and Saxomyces sp. to the shading output stage; Lepidostroma sp. and Saxomyces sp. to the dispatch stage; and Mycosphaerella populicola to the field stage. Teratosphaeria toledana and Teratosphaeria acidotherma were found at more than one developmental stage. Cladosporium sp. and Rhodosporidium fluviale colonized and persisted in plants at the dispatch and field stages. This is the first report of P. tridactyla, A. restrictus, E. patelii, Saxomyces and Lepidostroma sp. as endophytes in eucalipt.
Long-term charcoal-induced changes to soil properties in temperate regions of northern Iran

The long-term performance and benefits of charcoal application on the carbon sequestration and properties of forest soils in temperate or non-tropical regions has not been studied in detail in spite of its important role in global warming. This study was conducted to describe the long-term charcoal-induced changes in organic carbon (OC) content and other soil properties of temperate deciduous forests in Mazandaran province, northern Iran. Three sites were sampled to collect composite soil samples from two depths (0–20 and 20–40 cm) inside and outside of a plot of charcoal-enriched soils surrounding a historical charcoal production site (abandoned for more than 120 years). The presence of charcoal in soils for about 120 years elevated significantly the black carbon, total OC, natural soil OC, total nitrogen, dissolved organic matter, soil OC density, exchangeable bases, saturated hydraulic conductivity, available water capacity and available Fe, Mn and Zn compared to the adjacent reference soils. Cation exchange capacity (CEC) and pH were 15.5 cmolc kg-1 and 0.5 units, respectively, higher than the adjacent reference soils at 0–20 cm soil depth. However, electrical conductivity (EC), bulk density and available Cu were higher in the adjacent reference soil. The aged charcoal had no significant effect on the microbial respiration rate of studied soils. The results of this study provide new insights and strong support for the long-term benefits of biochar application as a management strategy for improving soil productivity as well as sequestering large quantities of durable carbon in soils of the region and mitigating global warming.
Land use change modeling through an integrated Multi-Layer Perceptron Neural Network and Markov Chain analysis (case study: Arasbaran region, Iran)

Temporal land use/land cover (LULC) change information provides a variety of applications for informed management of land resources. The aim of this study was to detect and predict LULC changes in the Arasbaran region using an integrated Multi-Layer Perceptron Neural Network and Markov Chain analysis. At the first step, multi-temporal Landsat images (1990, 2002 and 2014) were processed using ancillary data and were classified into seven LULC categories of high density forest, low-density forest, agriculture, grassland, barren land, water and urban area. Next, LULC changes were detected for three time profiles, 1990–2002, 2002–2014 and 1990–2014. A 2014 LULC map of the study area was further simulated (for model performance evaluation) applying 1990 and 2002 map layers. In addition, a collection of spatial variables was also used for modeling LULC change processes as driving forces. The actual and simulated 2014 LULC change maps were cross-tabulated and compared to ensure model simulation success and the results indicated an overall accuracy and kappa coefficient of 97.79% and 0.992, respectively. Having the model properly validated, LULC change was predicted up to the year 2025. The results demonstrated that 992 and 1592 ha of high and lowdensity forests were degraded during 1990–2014, respectively, while 422 ha were added to the extent of residential areas with a growth rate of 17.58 ha per year. The developed model predicted a considerable degradation trend for the forest categories through 2025, accounting for 489 and 531 ha of loss for high and low-density forests, respectively. By way of contrast, residential area and farmland categories will increase up to 211 and 427 ha, respectively. The integrated prediction model and customary area data can be used for practical management efforts by simulating vegetation dynamics and future LULC change trajectories.
Variations in root chemistry of three common forest species, southwestern China

Root chemistry varies with tree species and root diameter but little information is available about Tibetan forest species. The root chemistry of three root diameter classes (fine: 0–2 mm, medium: 2–5 mm, coarse: 5–10 mm) of three subalpine species (Abies faxoniana Rehd. and Wild, Picea asperata Mast., and Betula albosinensis Burkill) were investigated. Carbon concentrations, and carbon/nitrogen and carbon/phosphorus ratios increased but nitrogen, phosphorus and nitrogen/phosphorus ratios decreased with increasing root diameter. The roots of the conifers had higher carbon levels, and higher carbon/nitrogen and carbon/phosphorus ratios than birch roots. The opposite was found with nitrogen and phosphorus levels and nitrogen/phosphorus ratios. Lignin concentrations decreased but cellulose concentrations increased with greater root diameters. The results indicate that diameter-associated variations in root chemistry may regulate their contribution to detrital pools which has important implications for below-ground carbon and nutrient cycles in these subalpine forests.
Energy coupling mechanism of FO in a rotary ATP synthase: a model update

In nearly all living cells, rotary ATP synthases of the F1FO family are essential to inter-conversing of energy between the transmembrane electrochemical potential and the ATP form (Boyer 1997). During ATP synthesis, the FO sector of the ATP synthase machinery converts the electrochemical energy of either protons or sodium ions into mechanical energy of a rotor; in turn, this energy is converted into chemical energy of ATP by the F1 sector (Gruber et al. 2014; Nakamoto et al. 2008). A fundamental question here is as to why these driving substances are all electrically charged. The answer to this conundrum is likely to be related to the electric nature of the transmembrane potential. For a membrane protein whose functional cycle is driven by proton motive force (∆p), be it an F_O complex (Boyer 1988) or a secondary transporter (Zhang et al. 2015b, 2017), the driving force includes two parts, namely the electrostatic membrane potential (∆Ψ_M) and ∆pH. The corresponding energy terms are expressed as F∆Ψ_M and - 2.3RT∆pH, respectively. Whereas ∆Ψ_M is influenced by the capacitance of the lipid bilayer, ∆pH depends on buffer strength on either side of the membrane. Furthermore, the ∆pH-associated energy term is equivalent to the Nernst voltage of protons (Benedek and Villars 2000), i.e., V_N = - 2.3(RT/F)∆pH. Therefore, ∆p itself can be represented by an overall, effective membrane potential ∆Ψ_p = ∆Ψ_M+ V_N.
The CRIPSR /Cas gene-editing system-an immature but useful toolkit for experimental and clinical medicine

A Chinese scientist, Jiankui He, and his creation of the world ' s first genetically altered baby made headlines recently. As a newly developed gene-editing technique, the CRISPR/Cas system should not be applied to human beings for reproductive purposes until it has been extensively tested. However, numerous experimental research studies in human somatic, germline cells, and even in embryos, have been conducted, which have shown CRISPR/Cas to be a useful tool for human genome editing and a potential therapeutic method for future clinical use.
Knockout of ISCA 1 causes early embryonic death in rats

Background : I ron-sulfur cluster assembly 1 (I SCA1 ) is an iron-sulfur (Fe/S) carrier protein that accepts Fe/S from a scaffold protein and transfers it to target proteins including the mitochondrial Fe/S containing proteins. ISCA 1 is also the newly identified causal gene for multiple mitochondrial dysfunctions syndrome ( MMDS ). However, our knowledge about the physiological function of ISCA 1 in vivo is currently limited. In this study, we generated an ISCA 1 knockout rat line and analyzed the embryo development. Methods : I SCA 1 knockout rats were generated by replacing the exon1 of I SCA 1 gene with the mC herry-Cre fusion gene using CRISPR -Cas9 technology. The ISCA 1 expression pattern was analyzed by fluorescence imaging using ISCA 1 promotor driven Cre and mC herry expression. The embryonic morphology was examinated by microscope and mitochondrial proteins were tested by Western blot. Results : A n ISCA 1 knockout rat line was obtained, which expressed m Ch erry-Cre fusion protein. Both of the fluorescence images from mC herry and Cre induced mC herry in a reporter rat strain, showing that ISCA 1 expressed in most of the tissues in rats. The ISCA 1 knockout resulted in abnormal development at 8.5 days, with a significant decrease of NDUFA 9 protein and an increase of aconitase 2 ( ACO 2) in rat embryos. Conclusion : D eletion of ISCA 1 induced early death in rats. I SCA1 affected the expression of key proteins in the mitochondrial respiratory chain complex, suggesting that ISCA 1 has an important influence on the respiratory complex and energy metabolism.
Species diversity in restoration plantings:Important factors for increasing the diversity of threatened tree species in the restoration of the Araucaria forest ecosystem

The Araucaria forest ecosystem in southern Brazil is highly threatened:less than one percent of the original forest remains,and what is left is a fragmented agro-mosaic of mostly early-to-late secondary forest patches among high-yield agriculture and timber monocultures.Forest restoration initiatives in this region aim to restore degraded areas,however the limited number of species used in restoration projects represents a missed opportunity for species-rich plantings.High diversity plantings represent a larger number of functional groups and provide a targeted conservation strategy for the high number of threatened species within this ecosystem.This study interviewed nurseries (Ns) and restoration practitioners (RPs) in Parana and Santa Catarina states to identify what species are being cultivated and planted,and what factors are driving the species selection process.An average of 20 species were reportedly used in restoration plantings,most of which are common,widespread species.Baseline data confirms that Ns and RPs have disproportionately low occurrences of threatened species in their inventories and plantings,supporting findings from previous research.Questionnaire responses reveal that opportunities for seed acquisition are an extremely important factor in order for nurseries to increase their diversity of cultivated species.Results also suggest that facilitating speciesrich plantings for restoration practitioners would only be feasible if it did not increase the time required to complete planting projects,as it would minimize their ability to keep costs low.This study proposes solutions for increasing the number of species used in restoration practicedsuch as developing a comprehensive species list,fostering knowledge-sharing between actors,creating seed sharing programs,and increasing coordination of planting projects.Long-term strategies involve complimenting traditional ex situ approaches with emerging inter-situ and quasi in situ conservation strategies which simultaneously provide long-term preservation of genetic diversity and increase seed production of target species.
Recovery of threatened plant species and their habitats in the biodiversity hotspot of the Southwest Australian Floristic Region

The Southwest Australian Floristic Region (SWAFR) is a global biodiversity hotspot with high plant diversity and endemism and a broad range of threatening processes.An outcome of this is a high proportion of rare and threatened plant species.Ongoing discovery and taxonomic description of new species,many of which are rare,increases the challenges for recovery of threatened species and prioritisation of conservation actions.Current conservation of this diverse flora is based on integrated and scientific evidence-based management.Here we present an overview of current approaches to the conservation of threatened flora in the SWAFR with a focus on active management through recovery and restoration that is integrated with targeted research.Key threats include disease,fragmentation,invasive weeds,altered fire regimes,grazing,altered hydro-ecology and climate change.We highlight the integrated approach to management of threats and recovery of species with four case studies of threatened flora recovery projects that illustrate the breadth of interventions ranging from In situ management to conservation reintroductions and restoration of threatened species habitats.Our review and case studies emphasise that despite the scale of the challenge,a scientific understanding of threats and their impacts enables effective conservation actions to arrest decline and enhance recovery of threatened species and habitats.
A comparison of honeybee (Apis mellifera) queen, worker and drone larvae by RNA-Seq

Honeybees (Apis mellifera) have haplodiploid sex determination: males develop from unfertilized eggs and females develop from fertilized ones. The differences in larval food also determine the development of females. Here we compared the total somatic gene expression profiles of 2-day and 4-day-old drone, queen and worker larvae by RNASeq. The results from a co-expression network analysis on all expressed genes showed that 2-day-old drone and worker larvae were closer in gene expression profiles than 2- day-old queen larvae. This indicated that for young larvae (2-day-old) environmental factors such as larval diet have a greater effect on gene expression profiles than ploidy or sex determination. Drones had the most distinct gene expression profiles at the 4-day larval stage, suggesting that haploidy, or sex dramatically affects the gene expression of honeybee larvae. Drone larvae showed fewer differences in gene expression profiles at the 2-day and 4-day time points than the worker and queen larval comparisons (598 against 1190 and 1181), suggesting a different pattern of gene expression regulation during the larval development of haploid males compared to diploid females. This study indicates that early in development the queen caste has the most distinct gene expression profile, perhaps reflecting the very rapid growth and morphological specialization of this caste compared to workers and drones. Later in development the haploid male drones have the most distinct gene expression profile, perhaps reflecting the influence of ploidy or sex determination on gene expression.
高压氧联合机械通气治疗重症哮喘患者的疗效及对部分免疫因子的影响

哮喘为呼吸科常见疾病,主要症状为气道阻塞,气道慢性炎症是其病理改变,常反复发作,并有夜间或清晨发作加剧的特点。重症哮喘指哮喘引起严重的呼吸困难、缺氧、二氧化碳潴留,常规治疗后仍继续恶化,逐渐或迅速发展为呼吸衰竭。有研究显示,重症哮喘患者发生呼吸衰竭后死亡率高达38%。重症哮喘患者常需行机械通气治疗,机械通气是临床提高重症哮喘患者救治成功率的重要治疗方式。 有研究显示,高压氧能够纠正缺氧与肺水肿,维持水电解质平衡等,临床将其应用于哮喘治疗,且发现其能改善患者肺功能,减少哮喘发作。本研究采用高压氧联合机械通气治疗重症哮喘,探究其临床治疗效果及对患者部分免疫因子的影响,为临床治疗提供依据。
唐汉钧治疗浆细胞性乳腺炎临床经验

浆细胞性乳腺炎是多发的发生在非哺乳期或非妊娠期的乳房化脓性疾病。文章从总结要点,正确诊断;内外结合,辨证施治以及验案赏析等方面,总结唐汉钧教授治疗浆细胞性乳腺炎的经验,旨在体现唐师“未溃重内治,已溃重外治”,内外结合,辨证施治的学术思想。
基于“肢节痹病”的桂枝芍药知母汤的现代药理作用探讨

中医学中涉及的“肢节痹病”,多指机体因感受外界之风、寒、湿、热等邪气,导致经络痹阻或受损,或失于濡养,或气血不通而引起机体关节的肿大、疼痛、麻木,灼热、屈伸不利,使病人难以忍受甚至严重影响其生活质量,临床上常表现出渐进性,或反复发作的特点.桂枝芍药知母汤载于《金匮要略》,为中医临床治疗痹病的常用方剂,现今临床常以该方为基础方,加减用于类风湿性关节炎、痛风性关节炎等类似中医“肢节痹病”的病症,在缓解患者临床症状的同时亦能减少西药的使用剂量.文章对桂枝芍药知母汤所治疗的类风湿关节炎及痛风性关节炎的所对应的中医“肢节痹病”及其现代药理作用机制研究进行归纳,为指导临床用药,并对该方的进一步研究提供新思路、新方向.
共济失调-毛细血管扩张症合并胸部淋巴瘤影像表现一例

本文报道共济失调-毛细血管扩张症合并胸部淋巴瘤一例。患儿男,11岁,因咳嗽、呼吸困难1周人院。体检:双眼球结膜毛细血管扩张,眼球震颤,双手精细动作时伴震颤,行走不稳。颅脑MRI平扫见小脑萎缩,第四脑室扩大。胸部CT平扫及增强见中上纵隔见不规则软组织肿块,密度不均,与胸腺分界不清,增强扫描肿块不均匀强化。基因检测患儿确诊为共济失调-毛细血管扩张症。
中医药治疗黄褐斑的机制研究现状

黄褐斑是一种获得性色素沉着性皮肤病。由于外观的改变以及病情的反复发作,对患者的生活质量造成严重影响。黄褐斑的病因及发病机制尚未完全阐明。现代医学认为遗传因素、紫外线照射和性激素变化是黄褐斑发病的三大主要诱因,氧化应激、皮肤屏障、情志因素、血流动力学等也参与该病的发生发展。中医学认为黄褐斑病位在皮,病因在内,脏腑辨证与肝、脾、肾三脏功能失调相关,气血辨证与气滞血瘀相关,同时与胞宫失常、冲任失调及络病也密切相关[1]。笔者结合西医对黄褐斑发病机制的研究,就近几年中医药治疗黄褐斑作用机制的研究进展作一综述。
中国县级医院急诊科建设规范专家共识

中国县级行政区划(包括市辖区、县级市、县、旗等)中的县级医院主要是综合性医院和中医院,大多数为二级医院,部分为三级医院.县级医院作为县域内的医疗卫生中心,主要负责以常见病、多发病为主的医疗卫生服务及急危重症患者的救治任务.《“健康中国2030”规划纲要》强调“省域内人人享有均质化的危急重症、疑难病症诊疗和专科医疗服务”.国家卫健委《2018 -2020年改善医疗服务行动计划》中要求以急危重症为重点,创新急诊急救服务,为患者提供医疗救治绿色通道和一体化综合救治服务,构建快速、高效、全覆盖的急危重症医疗救治体系.然而,2018年10月《中华急诊医学杂志》编辑部对来源于30个省(直辖市)的828家县级医院急诊科现状的调查发现,县级医院急诊科存在发展不平衡、不充分、不规范、不稳定的现状,大部分县级医院急诊科普遍存在急诊发展模式不清晰、受重视程度不足、医务人员结构不合理、医疗设备不足或闲置、医疗技术落后等一系列问题.因此,以基于急诊急救大平台建设为核心的急诊科建设规范是落实国家卫健委要求的根本保障,也是国家医改成功的重要标志之一.