mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Relation of tea ingestion to salivary redox and flow rate in healthy subjects

The biochemistry of human saliva can be altered by food intake. The benefits of tea drinking were extensively studied but the influence of tea ingestion on human saliva has not been revealed. The work aimed to investigate the immediate and delayed effect of vine tea, oolong tea and black tea intake on certain salivary biochemistry and flow rate. The saliva samples of healthy subjects were collected before, after and 30 min after tea ingestion. The chemical compositions and antioxidant capacity of tea samples were analyzed to correlate with salivary parameters. Principal component analysis indicated that the effects of vine tea consumption were dominated by increasing salivary flow rate (SFR), production rate of total protein (TPC), thiol (SH), malondialdehyde, catalase activity and antioxidant capacity (FRAP) in saliva. The antioxidant profile of studied tea samples (FRAP, polyphenols, flavonoids) was positively correlated with salivary SFR, TPC, SH and FRAP but negatively correlated with salivary uric acid concentration in saliva.
Evaluation on the anisotropic brittleness index of shale rock using geophysical logging

The brittleness index plays a significant role in the hydraulic fracturing design and wellbore stability analysis of shale reservoirs. Various brittleness indices have been proposed to characterize the brittleness of shale rocks, but almost all of them ignored the anisotropy of the brittleness index. Therefore, uniaxial compression testing integrated with geophysical logging was used to provide insights into the anisotropy of the brittleness index for Longmaxi shale, the presented method was utilized to assess brittleness index of Longmaxi shale formation for the interval of 3155-3175 m in CW-1 well. The results indicated that the brittleness index of Longmaxi shale showed a distinct anisotropy, and it achieved the minimum value at β =45°-60°. As the bedding angle increased, the observed brittleness index (Bl_(2_β)) decreased firstly and increased then, it achieved the lowest value at β =40°-60°, and it is consistent with the uniaxial compression testing results. Compared to the isotropic brittleness index (β =0°), the deviation of the anisotropic brittleness index ranged from 10% to 66.7%, in other words, the anisotropy of brittleness index cannot be ignored for Longmaxi shale. Organic matter content is one of the main intrinsic causes of shale anisotropy, and the anisotropy degree of the brittleness index generally increases with the increase in organic matter content. The present work is valuable for the assessment of anisotropic brittleness for hydraulic fracturing design and wellbore stability analysis.
Noninvasive Diagnostic Technique for Nonalcoholic Fatty Liver Disease Based on Features of Tongue Images

Objective:To investigate a new noninvasive diagnostic model for nonalcoholic fatty liver disease (NAFLD) based on features of tongue images.Methods:Healthy controls and volunteers confirmed to have NAFLD by liver ultrasound were recruited from China-Japan Friendship Hospital between September 2018 and May 2019,then the anthropometric indexes and sampled tongue images were measured.The tongue images were labeled by features,based on a brief protocol,without knowing any other clinical data,after a series of corrections and data cleaning.The algorithm was trained on images using labels and several anthropometric indexes for inputs,utilizing machine learning technology.Finally,a logistic regression algorithm and a decision tree model were constructed as 2 diagnostic models for NAFLD.Results:A total of 720 subjects were enrolled in this study,including 432 patients with NAFLD and 288 healthy volunteers.Of them,482 were randomly allocated into the training set and 238 into the validation set.The diagnostic model based on logistic regression exhibited excellent performance:in validation set,it achieved an accuracy of 86.98%,sensitivity of 91.43%,and specificity of 80.61%;with an area under the curve (AUC) of 0.93 [95% confidence interval (CI) 0.68-0.98].The decision tree model achieved an accuracy of 81.09%,sensitivity of 91.43%,and specificity of 66.33%;with an AUC of 0.89 (95% CI 0.66-0.92) in validation set.Conclusions:The features of tongue images were associated with NAFLD.Both the 2 diagnostic models,which would be convenient,noninvasive,lightweight,rapid,and inexpensive technical references for early screening,can accurately distinguish NAFLD and are worth further study.
Hexamerin and allergen are required for female reproduction in the American cockroach, Periplaneta americana

Reproduction is of great importance for the continuation of the species. In insects, the fat body is the major tissue for nutrient storage and involved in vitellogenesis, which is essential for female reproduction. Here, 2 proteins, hexamerin and allergen, were separated from the fat bodies of adult female American cockroaches (Periplaneta americana) and identified as storage proteins, encoding for 733 amino acids with molecular weight of 87.88 kDa and 686 amino acids with molecular weight of 82.18 kDa, respectively. The encoding genes of these 2 storage proteins are mainly expressed in the fat body. RNA interference-mediated knockdown of Hexamerin and Allergen in the early stage of the first reproductive cycle in females suppressed vitellogenesis and ovarian maturation, indicating that these storage proteins are involved in controlling reproduction. Importantly, the expression of Hexamerin and Allergen was repressed by knockdown of the juvenile hormone (JH) receptor gene Met and the primary response gene Kr-h1, and was induced by methoprene, a JH analog, in both in vivo and in vitro experiments. Altogether, we have determined that hexamerin and allergen are identified as storage proteins and play an important role in promoting female reproduction in the American cockroach. The expression of their encoding genes is induced by JH signaling. Our data reveal a novel mechanism by which hexamerin and allergen are necessary for JH-stimulated female reproduction.
Activation of NRF2 by celastrol increases antioxidant functions and prevents the progression of osteoarthritis in mice

Excessive oxidative stress impairs cartilage matrix metabolism balance, significantly contributing to osteoarthritis (OA) development. Celastrol (CSL), a drug derived from Tripterygium wilfordii, has recognized applications in the treatment of cancer and immune system disorders, yet its antioxidative stress mechanisms in OA remain underexplored. This study aimed to substantiate CSL's chondroprotective effects and unravel its underlying mechanisms. We investigated CSL's impact on chondrocytes under both normal and inflammatory conditions. In vitro, CSL mitigated interleukin (IL)-1β-induced activation of proteinases and promoted cartilage extracellular matrix (ECM) synthesis. In vivo, intra-articular injection of CSL ameliorated cartilage degeneration and mitigated subchondral bone lesions in OA mice. Mechanistically, it was found that inhibiting nuclear factor erythroid 2-related factor 2 (NRF2) abrogated CSL-mediated antioxidative functions and exacerbated the progression of OA. This study is the first to elucidate the role of CSL in the treatment of OA through the activation of NRF2, offering a novel therapeutic avenue for arthritis therapy.
Extremely stable Li-metal battery enabled by piezoelectric polyacrylonitrile quasi-solid-state electrolytes

Polymer solid-state electrolytes (PSSEs) are promising for solving the safety problem of Lithium (Li) metal batteries (LMBs). However, PSSEs with low modulus in nature are prone to be penetrated by lithium dendrites, resulting in short circuit of LMBs. Here, we design and prepare piezoelectric BaTiO_3 doped polyacrylonitrile (PAN@BTO) quasi-solid-state electrolytes (PQSSEs) by electrostatic spinning method to suppress dendritic growth. The piezoelectric polymer electrolytes are squeezed by nucleation and growth processes of Li dendrites, which can generate a piezoelectric electric field to regulate the deposition of Li~+ ions and eliminate lithium bud. Consequently, piezoelectric PAN@BTO PQSSEs enables highly stable Li plating/stripping cycling for over 2 000 h at 0.15 mA/cm~2 at room temperature (RT, 25 ℃). Also, LiFePO_4|PAN@BTO|Li full cells demonstrate excellent cycle performance (136.9 mA$h/g and 78% retention after 600 cycles at 0.5 C) at RT. Moreover, LiFePO_4|PAN@BTO|Li battery show extremely high safety and can still work normally under high-speed impact (2 Hz, ~30 kPa). We construct an in-situ cell monitoring system and disclose that the mechanism of suppressed lithium dendrite is originated from the generation of opposite piezoelectric potential and the feedback speed of intermittent piezoelectric potential signals is extremely fast.
慢性乙型病毒性肝炎合并非酒精性脂肪肝:老问题新发现

2020年国际脂肪肝专家小组提出,用代谢相关脂肪性肝病(metabolic dysfunctional -associated fatty liver disease,MAFLD)取代非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD),且一致认为MAFLD相比NAFLD是更合适的研究术语。 NAFLD的诊断需要排除乙型肝炎病毒(HBV)感染, MAFLD的诊断不需要,因此相当数量的HBV感染合并肝脏脂肪变性病例会被诊断为MAFLD。根据MAFLD的定义,HBV和AFLD(HBV-AFLD)将成为MAFLD的两个重要人群分布。由于目前大多数数据来自NAFLD相关研究,本文仍使用NAFLD的命名。HBV感染和NAFLD作为导致慢性肝病的两个主要原因,也可导致肝硬化和肝细胞癌。虽然慢性乙型病毒性肝炎(CHB)患者的NAFLD患病率和发病率往往低于一般人群,但不可否认CHB患者并发NAFLD仍然很常见,且随着时间的推移呈上升趋势。有研究发现,NAFLD可促进乙肝表面抗原(HBsAg)的血清清除率,可能抑制HBV复制,但会加重肝纤维化。目前,并发NAFLD对CHB患者的HCC风险、全因死亡率和抗病毒治疗反应的影响仍存在争议,我们需要深层次的研究来明确HBV感染和脂肪性肝病的相互影响机制,从而制定更加准确的临床治疗和预后手段。数据显示,全球不同国家、不同区域CHB患者肝脂肪变的患病率相差很大(14%~76%)(图1)。从图中我们可以发现,2008年至2020年中国CHB合并NAFLD的患病率呈上升趋势(26.8%升至56.6%),上升超出1倍。中国香港地区2010年到2020年的患病率从43.6%升至48.8%,上升5.2%,与全球和亚洲地区CHB合并NAFLD流行率的上升趋势相一致。但韩国的发病率却出乎意料的降低(51.2%降至21.8%),而其他发达国家如美国、法国等国家的整体发病率也在逐步上升。因此,迫切需要更多高质量的大规模前瞻性研究来探索当前NAFLD对CHB患者HCC风险、全因死亡率和抗病毒治疗反应的确切影响。
Controllability of game-based multi-agent system

We introduce a strategy matrix, a novel concept for ensuring controllability in game-based control systems (GBCSs). This graph-based condition is presented as an alternative to utilizing complex mathematical calculations through algebraic conditions. Moreover, to address these issues, one must first study the expression of Nash equilibrium actions. This expression yields a general formula of the game controllability matrix, which is always affected by the specific matrix (strategy matrix) comprising Nash equilibrium actions, and the matrix can not only be obtained by matrix calculation but can also be directly written through the topology, indicating the topology’s specific influence on the GBCS. Finally, we build a new game-based multi-agent system and determine the controllability relationship between the system and the general system.
Co-Ru alloy nanoparticles decorated onto two-dimensional nitrogen doped carbon nanosheets towards hydrogen/oxygen evolution reaction and oxygen reduction reaction

Constructing highly-efficient electrocatalysts toward hydrogen evolution reaction (HER)/oxygen evolution reaction (OER)/oxygen reduction reaction (ORR) with excellent stability is quite important for the development of renewable energy-related applications. Herein, Co-Ru based compounds supported on nitrogen doped two-dimensional (2D) carbon nanosheets (NCN) are developed via one step pyrolysis procedure (Co-Ru/NCN) for HER/ORR and following low-temperature oxidation process (Co-Ru@RuO_x/NCN) for OER. The specific 2D morphology guarantees abundant active sites exposure. Furthermore, the synergistic effects arising from the interaction between Co and Ru are crucial in enhancing the catalytic performance. Thus, the resulting Co-Ru/NCN shows remarkable electrocatalytic performance for HER (70 mV at 10 mA cm~(-2)) in 1 M KOH and ORR (half-wave potential E1/2 = 0.81 V) in 0.1 M KOH. Especially, the Co-Ru@RuO_x/NCN obtained by oxidation exhibits splendid OER performance in both acid (230 mV at 10 mA cm~(-2)) and alkaline media (270 mV at 10 mA cm~(-2)) coupled with excellent stability. Consequently, the fabricated two-electrode water-splitting device exhibits excellent performance in both acidic and alkaline environments. This research provides a promising avenue for the advancement of multifunctional nanomaterials.
Multi-site anchoring of single-molecule for efficient and stable perovskite solar cells with lead shielding

The emergence of perovskite solar cells (PSCs) has greatly promoted the progress of photovoltaic technologies. The rapid development of PSCs has been driven by the advances in optimizing perovskite films and their adjacent interfaces. However, the polycrystalline perovskite layers in most highly efficient PSCs still contain various defects that greatly limit photovoltaic performance and stability of the devices. Herein, we introduce a multifunctional additive ethylene diamine tetra methylene phosphonic sodium (EDTMPS) with multiple anchor points into the precursor of perovskite to improve the efficiency and stability of PSCs and provide in-situ protection of lead leakage. The addition of EDTMPS acts as a crystal growth controller and passivation agent for perovskite films, thereby slowing down the crystallization rate of the film and obtaining high-quality perovskite films. Our study also provides an insight into how the modifier modulate the interfacial energy level arrangement as well as affect transfer of charge carriers and their recombination under photoinduced excitation. As a result, the power conversion efficiency (PCE) of single subcell with a working area of 0.255 cm~2 increases significantly from 20.03% to 23.37%. Moreover, we obtained a PCE of 19.16% for the 25 cm~2 module. Importantly, the unencapsulated EDTMP-modified PSCs exhibit better operational and thermal stability, as well as in-situ absorption of leaked lead ions.
Experimental Investigation on Macro Spray Characteristics of Octanol-Biodiesel-Diesel Ternary Fuel Blend

This study investigates the spray characteristics of ternary blends composed of octanol, biodiesel, and diesel fuel. Experiments are conducted using six materials to examine the variation in spray characteristic and to verify and compare a previously established spray tip penetration model with a modified model. The results show that the addition of OB100 (30% of octanol, 70% of biodiesel) improves the spray characteristics of the fuel. Specifically, the addition of 10% or 20% of OB100 leads to a slight increase in the spray tip penetration, average spray cone angle, maximum spray width, and the spray area of the fuel blend; however, further addition of OB100 causes a corresponding decrease in these parameters. Based on previous research, this study uses kinematic viscosity instead of dynamic viscosity and density to modify the prediction model of spray tip penetration. The modified model exhibits a better fit quality and agreement with the experimental data, making it more suitable for predicting the spray tip penetration of fuel blends compared to the Hiroyasu-Arai model.
Effect of Photovoltaic Power Generation on Carbon Dioxide Emission Reduction under Double Carbon Background

Increasing the efficiency and proportion of photovoltaic power generation installations is one of the best ways to reduce both CO_2 emissions and reliance on fossil-fuel-based power supplies. Solar energy is a clean and renewable power source with excellent potential for further development and utilization. In 2021, the global solar installed capacity was about 749.7 GW. Establishing correlations between solar power generation, standard coal equivalent, carbon sinks, and green sinks is crucial. However, there have been few reports about correlations between the efficiency of tracking solar photovoltaic panels and the above parameters. This paper calculates the increased power generation achievable through the use of tracking photovoltaic panels compared with traditional fixed panels and establishes relationships between power generation, standard coal equivalent, and carbon sinks, providing a basis for attempts to reduce reliance on carbon-based fuels. The calculations show that power generation efficiency can be improved by about 26.12% by enabling solar panels to track the sun’s rays during the day and from season to season. Through the use of this improved technology, global CO_2 emissions can be reduced by 183.63 Mt, and the standard coal equivalent can be reduced by 73.67 Mt yearly. Carbon capture is worth approximately EUR 15.48 billion, and carbon accounting analysis plays a vital role in carbon trading.
A transient model integrating the nanoconfinement effect and pore structure characteristics of oil transport through nanopores

Understanding the integrated transport behavior of oil in shale nanopores is critical to efficient shale oil development. In this paper, based on the time-dependent Poiseuille flow momentum equation, we present a novel transient model to describe oil transport in unsteady and steady states. The model incorporates the effect of the critical shift density, apparent viscosity, slip length, and alkane property, as well as pore tortuosity and surface roughness. We evaluated our model through a comparison with other models, experiments, and molecular dynamics simulations. The results show that the development rates of the volume flows of C_6-C_(12) alkane confined in inorganic nanopores and C_(12) alkane confined in organic nanopores were faster than that of the corresponding bulk alkane. In addition, the critical drift density positively promoted the volume flow development rate in the unsteady state and negatively inhibited the mass flow rate in the steady state. This effect was clearest in pores with a smaller radius and lowerenergy wall and in alkane with shorter chain lengths. Furthermore, both the nanoconfinement effect and pore structure determined whether the volume flow enhancement rate was greater than or less than 1. The rate increased or decreased with time and was controlled mainly by the nanoconfinement effect. Moreover, as the wall energy increased, the flow inhibition effect increased; as the carbon number of alkane increased, the flow promotion effect increased. The results indicate that the proposed model can accurately describe oil transport in shale nanopores.
Effects of CH_4/CO_2 multi-component gas on components and properties of tight oil during CO_2 utilization and storage: Physical experiment and composition numerical simulation

An essential technology of carbon capture, utilization and storage-enhanced oil recovery (CCUS-EOR) for tight oil reservoirs is CO_2 huff-puff followed by associated produced gas reinjection. In this paper, the effects of multi-component gas on the properties and components of tight oil are studied. First, the core displacement experiments using the CH_4/CO_2 multi-component gas are conducted to determine the oil displacement efficiency under different CO_2 and CH_4 ratios. Then, a viscometer and a liquid density balance are used to investigate the change characteristics of oil viscosity and density after multicomponent gas displacement with different CO_2 and CH_4 ratios. In addition, a laboratory scale numerical model is established to validate the experimental results. Finally, a composition model of multi-stage fractured horizontal well in tight oil reservoir considering nano-confinement effects is established to investigate the effects of multi-component gas on the components of produced dead oil and formation crude oil. The experimental results show that the oil displacement efficiency of multi-component gas displacement is greater than that of single-component gas displacement. The CH_4 decreases the viscosity and density of light oil, while CO_2 decreases the viscosity but increases the density. And the numerical simulation results show that CO_2 extracts more heavy components from the liquid phase into the vapor phase, while CH_4 extracts more light components from the liquid phase into the vapor phase during cyclic gas injection. The multi-component gas can extract both the light components and the heavy components from oil, and the balanced production of each component can be achieved by using multicomponent gas huff-puff.
Visualization of hydraulic fracture interacting with pre-existing fracture

Hydraulic fracturing is considered the main stimulation method to develop shale gas reservoirs. Due to its strong heterogeneity, the shale gas formation is typically embedded with geological discontinuities such as bedding planes and natural fractures. Many researchers realized that the interaction between natural fractures and hydraulic fractures plays a crucial role in generating a complex fracture network. In this paper, true tri-axial hydraulic fracturing tests were performed on polymethyl methacrylate (PMMA), on which pre-existing fracture was pre-manufactured to simulate natural fracture. A cohesive model has been developed to verify the results of the experimental tests. The key findings demonstrate that the experimental results agreed well with the numerical simulation outcomes where three main interaction modes were observed: crossing; being arrested by opening the pre-existing fracture; being arrested without dilating the pre-existing fracture. Crossing behavior is more likely to occur with the approaching angle, horizontal stress difference, and injection rate increase. Furthermore, the higher flow rate might assist in reactivating the natural fractures where both sides of the pre-existing fractures were reactivated as the injection rate increased from 5 to 20 mL/min. Additionally, hydraulic fractures show a tendency to extend vertically rather than along the direction of maximum horizontal stress when they are first terminated at the interface. This research may contribute to the field application of hydraulic fracturing in shale gas formation.
Material and device design for organic solar cells: towards efficiency and stability

Organic solar cells (OSCs) have garnered significant attention as a novel photovoltaic technology and have been extensively investigated. In recent years, OSCs have made rapid strides in power conversion efficiency (PCE), demonstrating their significant potential in practical applications. In addition to high PCE, the practical application of OSCs demands a prolonged operating lifespan. The rational design of materials and devices to achieve efficient and stable OSCs is pivotal. This feature article presents a thorough analysis of our group’s studies on enhancing efficiency and stability through material and device design. We introduce a range of exceptional chlorine-mediated organic photovoltaic materials and systematically summarize chlorine atom (Cl) induced effects on energy levels, molecular stacking, active layer film morphology and photovoltaic performance. Furthermore, the use of single-crystal diffraction technology allows for a comprehensive understanding of intermolecular packing and interaction at the molecular level. A series of highly efficient non-fullerene acceptors (NFAs) with threedimensional (3D) network packing structures are developed and discussed. Subsequently, based on efficient 3D network brominated NFAs, the studies on polymer and oligomer acceptor materials are carried out and achieve efficient and stable OSCs. In addition to materials design, the development of the “quasiplanar heterojunction” (Q-PHJ) based OSC device also plays an important role in achieving superior efficiency and stability. These design experiences of materials and devices hope to provide valuable guidance for the development of efficient and stable OSCs.