mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Biocompatibility evaluation of electrospun aligned poly(propylene carbonate)nanofibrous scaffolds with peripheral nerve tissues and cells in vitro

Background Peripheral nerve regeneration across large gaps is clinically challenging.Scaffold design plays a pivotal role in nerve tissue engineering.Recently,nanofibrous scaffolds have proven a suitable environment for cell attachment and proliferation due to similarities of their physical properties to natural extracellular matrix.Poly(propylene carbonate)(PPC)nanofibrous scaffolds have been investigated for vascular tissue engineering.However,no reports exist of PPC nanofibrous scaffolds for nerve tissue engineering.This study aimed to evaluate the potential role of aligned and random PPC nanofibrous scaffolds as substrates for peripheral nerve tissue and cells in nerve tissue engineering.Methods Aligned and random PPC nanofibrous scaffolds were fabricated by electrospinning and their chemical characterization were carried out using scanning electron microscopy (SEM).Dorsal root ganglia (DRG)from Sprague-Dawley rats were cultured on the nanofibrous substrates for 7 days.Neurite outgrowth and Schwann-cell migration from DRG were observed and quantified using immunocytochemistry and SEM.Schwann cells derived from rat sciatic nerves were cultured in electrospun PPC scaffold-extract fluid for 24,48,72 hours and 7 days.The viability of Schwann cells was evaluated by 3-[4,5-dimethyl(thiazol-2-yl)-2,5-diphenyl] tetrazolium bromide (MTT)assay.Results The diameter of aligned and random fibers ranged between 800 nm and 1200 nm,and the thickness of the films was approximately 10-20 μm.Quantification of aligned fiber films revealed approximately 90% alignment of all fibers along the longitudinal axis.However,with random fiber films,the alignment of fibers was random through all angle bins.Rat DRG explants were grown on PPC nanofiber films for up to 1 week.On the aligned fiber films,the majority of neurite outgrowth and Schwann cell migration from the DRG extended unidirectionally,parallel to the aligned fibers.However,on the random fiber films,neurite outgrowth and Schwann cell migration were randomly distributed.A comparison of cumulative neurite lengths from cultured DRGs indicated that neurites grew faster on aligned PPC films ((2537.6±987.3)μm)than randomly-distributed fibers ((493.5±50.6)μm).The average distance of Schwann cell migration on aligned PPC nanofibrous films ((2803.5±943.6)μm)were significantly greater than those on random fibers ((625.3±47.8)μm).The viability of Schwann cells cultured in aligned PPC scaffold extract fluid was not significantly different from that in the plain DMEM/F12 medium at all time points after seeding.Conclusions The aligned PPC nanofibrous film,but not the randomly-oriented fibers,significantly enhanced peripheral nerve regeneration in vitro,indicating the substantial role of topographical cues in stimulating endogenous nerve repair mechanisms.Aligned PPC nanofibrous scaffolds may be a promising biomaterial for nerve regeneration.
旱地,荒漠和荒漠化:探寻恢复之路——第三届国际荒漠化会议述评

2010年11月在以色列召开了第三届荒漠化国际学术研讨会,会议的主题是"旱地,荒漠和荒漠化:探寻恢复之路".会议设20个专题,可以归纳为8个科学问题,表现出了多学科性,地域广泛性及多尺度性,关注社会人文机制等突出特点.以色列在荒漠化防治,生态恢复与区域发展方面的辉煌成就以及本次会议所反映的国际前沿和趋势对中国有着重要启示:(1)加强技术研发和推广,提高干旱,半干旱区人口的可持续生计与能力建设是中国防治土地生态退化和荒漠化的关键所在;(2)在土地生态退化和恢复的研究和实践中必须重视社会人文因素的作用;(3)深化中国干旱,半干旱区全球变化响应与适应的研究,推动荒漠化防治,生态保护与恢复,全球变化方面的国际合作是一项非常紧迫的战略任务
Testing the distance-duality relation with data from galaxy clusters and type Ia supernovae

We test the distance-duality(DD)relation by combining the angular diameter distance DA provided by two galaxy cluster samples compiled by De Filippis et al.(the ellipticalβmodel)and Bonamente et al.(the sphericalβmodel),and the luminosity distance DL from Constitution and Union2 type Ia supernova(SNe Ia)datasets.To obtain DL associated with the observed DA at the same redshift,we smooth the noise of the SNe Ia in a model-independent way,obtain the evolutionary curve of DL and,finally,test the DD relation.We find that the ellipticalβmodel,when compared with the SNe Ia from the Constitution compilation,is only consistent with the DD relation at the 3σconfidence level(CL),while the sphericalβmodel is incompatible with the DD relation at the 3σCL.For the Union2 compilation,the De Filippis and Bonamente samples are marginally compatible with the validity of the DD relation at the 1σand 2σCLs,respectively.
New players in apoptosis

Researches on the area of apoptosis have achieved explosive progress over the past two decades.Two major regulating mechanisms of apoptosis have been uncovered in great details.One is called extrinsic apoptosis pathway,also known as the deathreceptor pathway.The extrinsic pathway is usually activated from outside the cell by TNF and other cytokines with their corresponding death receptors,such as TNF receptor,Fas,and TRAIL.The other is named intrinsic apoptosis pathway,also called as the mitochondrial pathway.The intrinsic pathway is activated responding to cell stresses or intracellular damage,such as DNA damage.So far,hundreds of proteins have been identified to be involved in the regulation of both extrinsic and intrinsic apoptosis pathways.And the collection of four research articles in this issue will provide new factors to this long list of apoptosis.[取自正文]
Plant Cell and Signaling Biology Blooms in the Wuyi Mountain

The Eighth International Conference on Plant Biology Frontiers,organized by Zhenbiao Yang,Chentao Lin,and Xingwang Deng,was convened in the Wuyi Mountain Yeohwa Resort in Fujian,China,23-27 September 2010.The meeting's main theme was Cells and Signals,featuring four keynote speeches,45 plenary talks,and over 40 poster presentations that covered a wide range of topics,from dynamic cellular structures to how developmental and environmental signals control various plant processes at the juncture of cells.[取自正文]
Induction of a 55 kDa acetylcholinesterase protein during apoptosis and its negative regulation by the Akt pathway

Acetylcholinesterase (AChE)is emerging as an important contributor to apoptosis in various cell types.However,overexpression of AChE does not initiate apoptosis,and cells which express AChE at basal levels grow normally,suggesting that AChE may function differently between normal and apoptotic conditions.In this study,we determined that an AChE-derived protein (~55 kDa)positively correlated with cellular apoptotic levels.The 55 kDa AChE protein was not a result of a novel splice variant of the AChE primary transcript.Instead,it was determined to be a cleaved fragment of the full-length 68 kDa AChE protein that could not be inhibited by cycloheximide (CHX)but could be suppressed by caspase inhibitors in apoptotic PC-12 cells.Furthermore,activation of the Akt cascade abolished the 55 kDa protein,and both AChE protein forms (68 and 55 kDa)accumulated in the nucleus during apoptosis.In a mouse model for ischemia/reperfusion (I/R)-induced acute renal failure,the 55 kDa AChE protein was detected in the impaired organs but not in the normal ones,and its levels correlated with the genotype of the mice.In summary,a 55 kDa AChE protein resulting from the cleavage of 68 kDa AChE is induced during apoptosis,and it is negatively regulated by the Akt pathway.This study suggests that an alternative form of AChE may play a role in apoptosis.
mTORC1 signaling:what we still don't know

The mammalian target of rapamycin (mTOR)is a protein kinase that plays key roles in cellular regulation.It forms complexes with additional proteins.The best-understood one is mTOR complex 1 (mTORC1).The regulation and cellular functions of mTORC1 have been the subjects of intense study; despite this,many questions remain to be answered.They include questions about the actual mechanisms by which mTORC1 signaling is stimulated by hormones and growth factors,which involves the small GTPase Rheb,and by amino acids,which involves other GTPase proteins.The control of Rheb and the mechanism by which it activates mTORC1 remain incompletely understood.Although it has been known for many years that rapamycin interferes with some functions of mTORC1,it is not known how it does this,or why only some functions of mTORC1 are affected.mTORC1 regulates diverse cellular functions.Several mTORC1 substrates are now known,although in several cases their physiological roles are poorly or incompletely understood.In the case of several processes,although it is clear that they are regulated by mTORC1,it is not known how mTORCI does this.Lastly,mTORC1 is implicated in ageing,but again it is unclear what mechanisms account for this.Given the importance of mTORC1 signaling both for cellular functions and in human disease,it is a high priority to gain further insights into the control of mTORC1 signaling and the mechanisms by which it controls cellular functions and animal physiology.
An Updated GA Signaling 'Relief of Repression' Regulatory Model

Gibberellic acid (GA)regulates many aspects of plant growth and development.The DELLA proteins act to restrain plant growth,and GA relieves this repression by promoting their degradation via the 26S proteasome pathway.The elucidation of the crystalline structure of the GA soluble receptor GID1 protein represents an important breakthrough for understanding the way in which GA is perceived and how it induces the destabilization of the DELLA proteins.Recent advances have revealed that the DELLA proteins are involved in protein-protein interactions within various environmental and hormone signaling pathways.In this review,we highlight our current understanding of the 'relief of repression' model that aims to explain the role of GA and the function of the DELLA proteins,incorporating the many aspects of cross-talk shown to exist in the control of plant development and the response to stress.
Prediction and Validation of Promoters Involved in the Abscisic Acid Response in Physcomitrella patens

Detection of cis-regulatory elements,such as transcription factor binding sites (TFBS),through utilization of ortholog conservation is possible only if genomic data from closely related organisms are available.An alternative approach is the detection of TFBS based on their overrepresentation in promoters of co-regulated genes.However,this approach usually suffers from a high rate of false-positive prediction.Here,we have conducted a case study using promoters of genes known to be strongly induced by the phytohormone abscisic acid (ABA)in the model plant Physcomitrella patens,a moss.Putative TFBS were detected using three de novo motif detection tools in a strict consensus approach.The resulting motifs were validated using data from microarray expression profiling and were able to predict ABA-induced genes with high specificity (90.48%)at mediocre sensitivity (33.33%).In addition,27 genes predicted to contain ABA-responsive TFBS were validated using real-time PCR.Here,a total of 37% of the genes could be shown to be induced upon ABA treatment,while 70% were found to be regulated by ABA.We conclude that the consensus approach for motif detection using coregulation information can be used to identify genes that are regulated under a given stimulus.In terms of evolution,we find that the ABA response has apparently been conserved since the first land plants on the level of families involved in transcriptional regulation.
IPCC《可再生能源与减缓气候变化特别报告》及其对应对气候变化前景的影响分析

应对气候变化和能源安全已成为全球性的重大问题,在此背景下,2008年4月在布达佩斯召开的政府间气候变化专门委员会(IPCC)第28次全会上,决定由IPCC第三工作组组织编写《可再生能源与减缓气候变化特别报告》(以下简称SRREN)①。全球 120多位专家,先后举行6次会议,历时2年半,完成了SRREN的编写。2011年5月,IPCC第三工作组第11次会议、IPCC第33次全会先后审议批准、接受了该报告。此份报告是IPCC第五次评估期间发布的首份报告,必将有助于更好地推动全球应对气候变化的行动。[取自正文]
Risk Assessment and Ecological Effects of Transgenic Bacillus thuringiensis Crops on Non-Target Organisms

The application of recombinant DNA technology has resulted in many insect-resistant varieties by genetic engineering (GE).Crops expressing Cry toxins derived from Bacillus thuringiensis (Bt)have been planted worldwide,and are an effective tool for pest control.However,one ecological concern regarding the potential effects of insect-resistant GE plants on non-target organisms (NTOs)has been continually debated.In the present study,we briefly summarize the data regarding the development and commercial use of transgenic Bt varieties,elaborate on the procedure and methods for assessing the non-target effects of insect-resistant GE plants,and synthetically analyze the related research Kong-MingWu results,mostly those published between 2005 and 2010.A mass of laboratory and field studies have shown that the currently available Bt crops have no direct detrimental effects on NTOs due to their narrow spectrum of activity,and Bt crops are increasing the abundance of some beneficial insects and improving the natural control of specific pests.The use of Bt crops,such as Bt maize and Bt cotton,results in significant reductions of insecticide application and clear benefits on the environment and farmer health.Consequently,Bt crops can be a useful component of integrated pest management systems to protect the crop from targeted pests.
Functions and Application of the AP2/ERF Transcription Factor Family in Crop Improvement

Plants have acquired sophisticated stress response systems to adapt to changing environments.It is important to understand plants' stress response mechanisms in the effort to improve crop productivity under stressful conditions.The AP2/ERF transcription factors are known to regulate diverse processes of plant development and stress responses.In this study,the molecular characteristics and biological functions of AP2/ERFs in a variety of plant species were analyzed.AP2/ERFs,especially those in DREB and ERF subfamilies,are ideal candidates for crop improvement because their overexpression enhances tolerances to drought,salt,freezing,as well as resistances to multiple diseases You-Zhi Ma in the transgenic plants.The comprehensive analysis of physiological functions is useful in elucidating the biological roles of AP2/ERF family genes in gene interaction,pathway regulation,and defense response under stress environments,which should provide new opportunities for the crop tolerance engineering.
Evolutionary History and Complementary Selective Relaxation of the Duplicated PI Genes in Grasses

Gene duplication plays an important role in the evolution of organisms by allowing functional innovation and the divergence of duplicate genes.Previous studies found two PI-like genes in grass species,suggesting functional divergence between the paralogous copies.Here,we reconstructed the evolutionary history of two PI genes from major lineages of grasses and other monocot species,and demonstrated that two PI genes(PI1 and PI2)arose from a whole genome duplication that occurred in a common ancestor of extant grasses.Molecular evolutionary analyses at the family and tribal levels found strong purifying selection acting on two genes in grasses,consistent with the conserved class B function of the PI genes.Importantly,we detected different patterns of selective relaxation between the duplicated PI genes although no signature of positive selection was found.Likelihood ratio tests revealed that theω ratio for M domain is significantly higher in PI1 than in PI2 but that for K domain is significantly higher in PI2 than in PI1.These findings imply that complementary selective relaxation occurs in two PI genes after duplication,and provide additional molecular evidence for the subfunctionalization of the duplicated PI genes in grasses.
miRNA对免疫和炎症反应的调节功能

发现microRNAs(miRNAs)是近年来的一个重要科学突破,使我们对基因调控有了新的认识。miRNAs广泛存在于从植物、线虫到人类的细胞中[1]。成熟miRNA能够通过核酸序列互补与特定的目标mRNA分子结合,使之降解或抑制其翻译,从而影响蛋白质的合成,最终达到调控基因表达的目的。miRNAs的主要功能是参与调控一系列生理过程,如增值、分化、细胞凋亡信号转导和器官发育等[1,2]。约有1/3人mRNAs是miRNA调控的目标基因。[取自正文]
多发性多生牙1例

国内报道的恒牙列多生牙发生率为1%~3%,其中 85.4%的患者只有1~2颗多生牙,3颗以上较少见,多生牙多为单生,成对者少见[1]。多生牙的好发部位报道结果大致分为两种,上颌切牙区,其次是位于上颌磨牙远中的上颌第四磨牙;有时也可在下颌磨牙区或非萌牙区等。也有报道为上颌切牙区是多生牙好发部位,其次是前磨牙区[2]。本案病例从发生部位看符合后者所报道,从发生数目看,不但多发,成对,而且并列双生。从牙冠的形态上看接近于前磨牙。不除外家族史。该患者自述,同胞弟弟也拔除过多生牙,虽未得到证实,但仍可有一定的参考价值。该患者右上颌侧切牙及下颌侧切牙均缺失。有研究报道,遗传学研究证明,非综合性少数牙先天缺失主要与MSX1基因突变或缺失有关[3]。在多发多生牙的同时存在缺失牙,曾见报道[4],该患者曾拔除过右上颌多生小牙,也不能完全排除误拔除恒牙[取自正文]
研究口源性口臭患者舌背细菌的方法和进展

口臭(oral malodor,halitosis)是指呼吸时口腔发出的不良气味,是一种长期困扰人们的口腔常见症状,严重时可影响人们进行正常的社会交往而造成心理障碍。其中,口源性口臭约占口臭的85%~90%[1]。口源性口臭主要是由口腔内细菌腐败分解含硫氨基酸、多肽和蛋白质产生的挥发性硫化物(volatile sulfur compounds,VSCs)和具有异味的脂肪酸所导致。而舌背表面则是口腔中聚集大量细菌的场所之一。这是由于舌背自身独特的条件所造成,如舌背的基底层和其表面覆盖的唾液含有大量的营养物质,舌背表面的裂隙和皱褶可以形成良好的微氧环境,以及舌背所受咀嚼力的影响较小[2,3]。自从1966年Gordon首次研究舌背细菌与口源性口臭关系后,人们逐渐意识到相比牙周袋内的细菌,舌背细菌是牙列完整和牙周健康的人群产生口源性口臭更为重要的因素[4]。目前,舌背细菌的研究除了关注与口源性口臭相关的舌背优势菌以外,也全局性地探索了舌背细菌多样性与口源性口臭之间的关系。本文总结了研究口源性口臭患者舌背细菌的方法和进展,并对每种方法逐一评述。[取自正文]
Investigation on Semi-conductive Properties of Hot Growth Film on 316L Austenitic Stainless Steel

The semi-conductive performances of hot growth film on 316L stainless steel were studied by means of electrochemical impedance spectroscopy(EIS)and Mott-Schottky analysis.The chemical compositions of the hot growth films were detected by X-ray photoelectron spectroscopy(XPS).The results show that the transfer resistance and film resistance increase with increasing temperature to 400°C,then they decrease sharply with further continuously increasing temperature.Formation time plays an important role in determining the electron properties of the hot growth film,when formation time reaches to 1 d,the transfer resistance and film resistance reach to the maximum value.Hot growth film has better anticorrosion behaviour in bicarbonate/carbonate solution containing chloride ions or sulfide ions.Mott-Schottky analysis reveals that hot growth film has n-p type semi-conductive property.XPS results show that the hot growth film is mainly composed of the inner chromium oxide and the outer iron oxide.
Stereoselectivities inα-andβ-Amino Acids Catalyzed Mannich Reactions Involving Cyclohexanone

The effects of two different amino acid catalysts on the stereoselectivities in the direct Mannich reactions of cyclohexanone,p-anisidine and p-nitrobenzaldehyde were studied with the aid of density functional theory.Transition states of the stereo-determining C―C bond-forming step with the addition of enamine intermediate to the imine for the L-proline(α-amino acid)and(R)-3-pyrrolidinecarboxylic acid(β-amino acid)-catalyzed processes were reported.B3LYP/6-31G~** calculations provide a good explanation for the opposite syn vs.anti diastereoselectivities of these two different kinds of catalysts(syn-selectivity for theα-amino acid catalysts,anti-selectivity for theβ-amino acid catalysts).Calculated and observed diastereomeric ratio and enantiomeric excess values are in reasonable agreement.
Genetic algorithm for A-optimal translation sequence of rough communication

In rough communication,because each agent has a different language and can not provide precise communication to each other,the concept translated among multi-agents will loss some information,and this results in a less or rougher concept.With different translation sequences the amount of the missed knowledge is varied.The A-optimal translation sequence of rough communication,which concerns both every agent and the last agent taking part in rough communication to get information as much as he (or she)can,is given.In order to get the A-optimal translation sequence,a genetic algorithm is used.Analysis and simulation of the algorithm demonstrate the effectiveness of the approach.
甲氨蝶呤联合米非司酮治疗输卵管妊娠48例临床分析

目的:观察甲氨蝶呤联合米非司酮治疗输卵管妊娠的疗效。方法:2006年1月至2009年12月我院收治96例未破裂型输卵管妊娠患者,随机分为研究组和对照组各48例,研究组采用甲氨蝶呤联合米非司酮治疗,对照组给予甲氨蝶呤治疗,比较观察两组的临床疗效及副反应。结果:研究组包块缩小率、血β-HCG下降≥30%、平均住院时间与对照组比较,差异有统计学意义(P＜0.05)。治疗后患侧输卵管再通率研究组(75.0%,24/32)明显高于对照组(64.3%,18/ 28)。结论:甲氨蝶呤联合米非司酮保守治疗输卵管妊娠,方法简便,疗效高,疗程短,副反应小,可保留生育功能,患者易于接受
PROCESS CONTROL OF THE SAND WAVE MIGRATION IN BEIBU GULF OF THE SOUTH CHINA SEA

Based on the environment characteristics of the Beibu Gulf of South China Sea,a quasi-three-dimensional physical model is built.By coupling the bottom boundary layer with the two-dimensional tidal current field near the seabed surface,the quasi-three-dimensional hydrodynamic numerical simulation is carried out.The sand wave migration process is dealt with by coupling the hydrodynamic model with the sediment transport model.The computational results are shown to be in good agreement with the observed data,which indicates that the quasi-three-dimensional physical model can be used to simulate the migration process for small scale sand waves.Then,based on measured data,the evolution of the sand wave migration is investigated.An effective formula is developed to predict the migration rate,in which not only the effects of the environment but also the features of sand waves are considered.
A PARTIALLY-AVERAGED NAVIER-STOKES MODEL FOR HILL AND CURVED DUCT FLOW

Turbulent flows past hill and curved ducts exist in many engineering applications.Simulations of the turbulent flow are carried out based on a newly developed technique,the Partially-Averaged Navier-Stokes(PANS)model,including separation,recirculation,reattachment,turbulent vortex mechanism.The focus is on how to accurately predict typical separating,reattaching and secondary motion at a reasonable computational expense.The effect of the parameter,the unresolved-to-total ratio of kinetic energy(k_f),is examined with a given unresolved-to-total ratio of dissipation(f_ε)for the hill flow with a much coarser grid system than required by the LES.An optimal value of k_f can be obtained to predict the separation and reattachment locations and for more accurate simulation of the resolved turbulence.In addition,the turbulent secondary motions are captured by a smallerk_f as compared with the RANS method with the same grid.
中国炭素企业国际化经营发展环境分析

中国炭素(本文主要指石墨电极,下同)企业在国际化经营之路上取得了很大的进步和不俗的成就。但不可否认的是,目前中国炭素企业的国际化发展水平还普遍偏低,在开展国际化经营过程中走了不少弯路,不得要领,屡屡碰壁。为此有必要弄清中国炭素企业国际化经营的基本情况,并在深入分析中国炭素企业国际化经营环境的基础上,探索出中国炭素企业国际化经营发展的健康之路。[取自正文]
求职面试的准备和技巧

面试是语言、思维、动作、神态的集中表现过程。有时胜败就取决于细节,而这些细节可能由平时的习惯所致。例如,平时不注重发型,面试时就可能给人一种缺乏职业形象的感觉;有的人喜欢侃侃而谈,在面试时可能过于随意;见面说话从来不笑,让面试官觉得你把面试当成一种折磨。[取自正文]
针灸联合脑波治疗仪干预军人心理应激反应33例分析

心理应激反应是影响部队战斗力的重要因素[1-2]。对军人心理应激反应进行干预非常重要。本研究采用针灸联合脑波治疗仪对33例军人的心理应激反应进行干预,观察其治疗效果。[取自正文]
经典瞬时受体电位通道与细胞增殖

TRPC家族是一类能通透钙离子的非选择性阳离子通道,主要被磷脂酶C通路所激活。近年来一些研究发现TRPC的某些成员与细胞增殖密切相关,从而参与许多疾病的病理生理过程。本文就TRPC家族成员一般特性及参与细胞增殖方面功能予以综述
TMEM16/ANOCTAMIN:最新的氯通道家族

Cl-通道参与许多生理过程,包括跨上皮细胞的离子吸收与分泌、平滑肌与骨骼肌收缩、神经元兴奋性、器官感知功能及细胞容积调节等。目前对于许多类型Cl-通道的分子构型尚不清楚。新近三个独立的研究小组同时发现Ano1是一种与钙离子激活氯通道(calcium-activated chloride channels,CaCCs)活性密切相关的膜蛋白。Ano1与其它9个成员共同组成Anoctamin家族。所有 Anoctamin蛋白都具有类似结构,推测含8个跨膜结构域以及胞质N-末端和C-末端。Ano1和Ano2的表达都与CaCCs类似,但其它Anoctamin蛋白的作用仍然未知
Synthesis and Crystal Structure of a Dinuclear Complex of Cu(II)with Tetra(3,5-diphenyl pyrazole)

A Cu(II)complex of tetra(3,5-diphenyl pyrazole)[Cu(C_(15)H_(12)N_2)_2Cl_2]_2 (1)was synthesized,and its structure was determined by single-crystal X-ray diffraction and further characterized by elemental analysis,NMR and IR.1 belongs to the monoclinic system,space group P2_1/c with a = 13.3780(5),b = 15.1392(6),c = 15.5923(6)A,β = 124.522(2)°,Z= 2 and V= 2601.86(17)A~3.In 1,each Cu~(2+)ion is coordinated with two N atoms from two tetra(3,5-diphenyl pyrazole)ligands and three Cl- anions to give a distorted square-pyramidal geometry,which is further linked through edge-sharing bridging by Cl- anions to form a centrosymmetric dinuclear structure.
化生性胸腺瘤临床病理分析及文献复习

目的 探讨化生性胸腺瘤的临床病理学和生物学行为特点。方法 对2例纵隔化生性胸腺瘤进行临床特征、组织病理形态学、影像诊断学和免疫组化研究,并复习相关文献。结果 2例患者均为男性,分别为35、38岁,CT提示前纵隔占位,境界清楚。组织学表现为典型的双相性表现,上皮细胞区域和梭形细胞区域交错分布,间质散在少许淋巴细胞,肿瘤细胞无明显异型性。免疫表型:上皮细胞区域Ckpan(+),CD5(-),梭形细胞区域Vimentin(+),Ckpan(-)。结论 化生性胸腺瘤是一种少见的肿瘤,有着与普通胸腺瘤截然不同的组织学形态,肿瘤一般无复发或转移,是一种恶性潜能较低的胸腺瘤亚型
PPH治疗内痔及混合痔45例临床分析

吻合器痔上黏膜环切术(PPH)是近年来痔手术治疗的进展之一。我科自2009年7月~2010年 9月,采用PPH技术配合辅助手术治疗内痔及混合痔45例,取得了较好的疗效,报道如下。[取自正文]
重组活性Ⅶ因子治疗危重出血6例报告

本组6例DIC患者应用rFⅦa 12 h内DIC症状体征消失,PT、APTT和FGB迅速恢复正常。6例患者应用rFⅦa后出血迅速控制,最快起效时间为10 min,输注rFⅦa后,HB未再降低,说明已无显性出血,应用rFⅦa均取得了很好的止血效果。证明rFⅦa对各种原因所致的DIC短期内止血效果显著,是一种较好的止血药物。在这些病例中,使用rFⅦa后输注红细胞、纤维蛋白原及冷沉淀的量均减少,但不是所有患者对于以上成分输血的需要量均下降。因其主要对短期内止血有重要作用,这给治疗原发病提供了更多的治疗机会,对于发生大量失血的患者,即使应用rFⅦa后出血量减少,还应给予充足的红细胞及血浆的输注,对后期成功治疗有重要意义。[取自正文]