mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
侵袭性梭形和多形性肌纤维母细胞肉瘤14例临床病理及超微结构观察

目的探讨伴有肌源性分化的梭形和多形性肌纤维母细胞肉瘤临床病理特点、免疫表型、诊断及鉴别诊断。方法收集2011-2017年空军军医大学(第四军医大学)西京医院14例发生于骨与软组织及脏器的梭形和多形性肌纤维母细胞肉瘤。男性和女性患者各7例,年龄17~74岁,平均年龄41岁。临床上,大多表现为进行性增大的疼痛性软组织包块或溶骨性破坏。应用免疫组织化学及电镜进行观察并随访。结果肿瘤由梭形、上皮样或多形细胞组成,呈束状、席纹状或不规则排列;核分裂象(10~28)/10 HPF;伴有不同程度坏死、胶原沉积和炎性细胞浸润。按法国癌症中心联盟(FNCLCC)分级,5例2级,9例3级。超微结构观察:肿瘤细胞具有肌膜下细小的束状肌丝、密体和密斑。免疫组织化学检测:肿瘤细胞呈广泛和弥漫性平滑肌肌动蛋白(10/14)和/或结蛋白(4/14)阳性,而其他定向分化标志物均阴性。随访2~156个月,9例死亡(3例复发),7例转移。结论梭形和多形性肉瘤伴有明显而又广泛的肌源性分化,其超微结构与肌纤维母细胞分化一致者应诊断为侵袭性梭形和多形性肌纤维母细胞肉瘤。该肿瘤预后差。
SZ-5 Cabin's Height Changes during Three Super-storms in 2003

In this work,the daily height variations of SZ-5(Shenzhou-5)cabin from 22 October to 28 November in 2003 are analyzed,which includes the period of the Halloween Storm and the Great November Storm.The significant orbital decays have been observed at the end of October and in late November due to the great solar flares and the severe geomagnetic storms.According to the equation of the air-drag-force on a spacecraft and the SZ-5 orbital decay information,the relative daily average thermospheric density changes during the three 2003 super-storms are derived and the results are compared with the Naval Research Laboratory Mass Spectrometer Incoherent Scatter Radar Extended Model(NRLMSISE-00).The results show that the daily average thermospheric density(at the altitude of SZ-5,about 350 km)in storm time enhances to approximately 200% as much as that in the quiet time but the empirical model may somewhat underestimate the average thermospheric density changes and the daily contributions of geomagnetic storms to the density enhancements during these severe space weather events.
Development and evaluation of a double-plane detector system for multi-radionuclide imaging

Purpose To develop a multi-radionuclide imaging system with a flexible and compact structure that has a potential for breast and other applications,and to evaluate its performances under both positron emission tomography and single photon emission imaging conditions.Methods The plane detector was composed of 5×6 blocks with an effective detection area of 168.6 mm×202.4 mm.Each block consisted of a 16×16 LYSO array.The pixel size is 1.9 mm×1.9 mm×15 mm.An 8×8 silicon photomultiplier (SiPM) array with SensL’s C-30035 sensors was coupled to the LYSO array,separated by a 1.5-mm-thick glass.To minimize the influence of temperature on the detector,the active part of the front-end electronics was kept away from SiPMs.Self-designed data acquisition system and reconstruction software were utilized to evaluate the performances of the whole system.Results All the blocks had excellent pixels identification.An average energy resolution of 11.39% for 511 keV and 21.37% for 140 keV was obtained.In the PET mode,the best spatial resolution was better than 2 mm and the system sensitivity reached up to 11.05% at 60 mm distance.In the single photon emission imaging mode,a spatial resolution better than 3 mm was obtained.Conclusion The results indicated that the system has a good overall performance and can be used in breast imaging and other general PET applications.It also has the potential to be used for single photon emission imaging.In pursuit of a better spatial resolution of cross-plane,PSF and DOI technology will be developed in the next work.For specific applications,further improvement of the detector system such as performance evaluation with phantoms will be carried out.
Improved projection-based energy weighting for spectral CT

Purpose Conventional X-ray CT scanners have limited ability to distinguish low-contrast substances.However,spectral CTs with photon counting detectors can identify photon energy and utilize spectral information,which is expected to achieve improved contrast.Energy weighting is a kind of reconstruction method for spectral CT.By assigning appropriate weight for each energy channel,the image contrast can be improved.Hence,how to determine the optimal weights is very important.Methods In this paper,we developed an improved projection-based energy weighting model for spectral CT.In this model,the object thickness of low-density materials is assumed as a constant,and the measured spectrum distribution is used to calculate the weight coefficients.Both phantom and tissue experiments were conducted in spectral CT scanner.Results The results showed that the thickness of low-density materials has little influence on the energy weight,so it can be regarded as a constant.For low-contrast phantom,the contrast-to-noise ratio was improved ~ 32% by the proposed projectionbased weighting method.Conclusions The improved projection-based energy weighting model is effective in practice.It can increase the contrast of low-density materials.
The study of linearity and detection efficiency for 20'' photomultiplier tube

Background The linearity and photon detection efficiency (PDE) are important parameters of photomultiplier tube (PMT), which need to be precisely measured with suitable techniques. Purpose To search good methods for linearity and PDE study of newly developed 20-inch PMT. Methods In this paper, we setup a testing system to use the average photoelectrons (P.E.) in pulse mode for linearity measurement with the result corrected for strong light. For the PDE measurement, we developed a relative method with a reference PMT whose efficiency is known to compare the measured PDE with both average charge and hit numbers. Results The measurements of PMT shows only 5% nonlinearity within 1000 P.E. and good PDE, the result of linearity's corrected definition is closer to the real status of PMT. Conclusions The results show good charge and linearity response for newly developed 20-inch MCP PMT and dynode PMT. The testing techniques discussed in this paper are suitable for the study of PDE and linearity.
Distal posterior inferior cerebellar artery aneurysm with cerebellar arteriovenous malformation treated by open surgery: a case report

Background: The detection of a feeder aneurysm and an arteriovenous malformation (AVM) is relatively rare for the intracranial AVM. The distal posterior inferior cerebellar artery aneurysm (DPICAAn) is reported to coexist or relate with the cerebellar AVM. In previous reports about the treatment of a DPICAAn and a cerebellar AVM, endovascular embolization with the sacrifice of the posterior inferior cerebellar artery (PICA) has often been selected. However, there have been few reports of simultaneous open surgery for coexistent cases of DPICAAn and cerebellar AVM. Case description: A 67-year-old male presented with a headache. We detected a right DPICAAn in the telovelotonsillar segment and a cerebellar AVM primarily fed by the left superior cerebellar artery (SCA). In addition, the nidus was located medially in the left upper cerebellar hemisphere. Magnetic resonance imaging raised suspicions of asymptomatic past hemorrhage in the cerebellar AVM. The left PICA was agenesis, and the right PICA perfused the bilateral inferior cerebellar hemispheres; thus, the right PICA could not be sacrificed. We selected open surgery to prevent any hemorrhagic event from the DPICAAn and the cerebellar AVM. The cerebellar AVM was completely removed, and the DPICAAn was successfully clipped in a single-session open surgery. Conclusions: Open surgery can be considered for DPICAAn and cerebellar AVM. The anatomical location of the DPICAAn and AVM contributed to the success of a single-session open surgery.
Differential evolution based computation intelligence solver for elliptic partial differential equations

A differential evolution based methodology is introduced for the solution of elliptic partial differential equations(PDEs)with Dirichlet and/or Neumann boundary conditions. The solutions evolve over bounded domains throughout the interior nodes by minimization of nodal deviations among the population. The elliptic PDEs are replaced by the corresponding system of finite difference approximation, yielding an expression for nodal residues. The global residue is declared as the root-mean-square value of the nodal residues and taken as the cost function. The standard differential evolution is then used for the solution of elliptic PDEs by conversion to a minimization problem of the global residue. A set of benchmark problems consisting of both linear and nonlinear elliptic PDEs has been considered for validation, proving the effectiveness of the proposed algorithm. To demonstrate its robustness, sensitivity analysis has been carried out for various differential evolution operators and parameters. Comparison of the differential evolution based computed nodal values with the corresponding data obtained using the exact analytical expressions shows the accuracy and convergence of the proposed methodology.
A comprehensive error calibration method based on dual uniform circular array

Based on the dual uniform circular array, a novel method is proposed to estimate the direction-of-arrival(DOA)and jointly calibrate gain-phase errors, position errors, and mutual coupling errors. In this paper, only one auxiliary source is required to generate three time-disjoint calibration sources with the help of the rotation platform. Subsequently, according to the principle that the signal subspace is orthogonal to the noise subspace, the cost function is constructed. The alternating iteration method is used to estimate the coefficients of the three kinds of errors. During the process, the proposed algorithm makes full use of the structural characteristics of the array when estimating mutual coupling errors, while the signal phase matrix is used to eliminate the phase influence caused by the delay in signal arrival at the antenna array when estimating gain-phase errors and position errors. Compared with the algorithm using multidimensional nonlinear search, the proposed algorithm has lower computational complexity. Moreover, our algorithm does not require additional auxiliary sensors. Simulation results demonstrate that the proposed algorithm is effective and can precisely and comprehensively calibrate the errors in a dual uniform circular array.
Interactions of drug-metabolizing enzymes with the Chinese herb Psoraleae Fructus

Psoraleae Fructus (the dried fruits of Psoralea corylifolia), one of the most frequently used Chinese herbs in Asian countries, has a variety of biological activities. In clinical settings, Psoraleae Fructus or Psoraleae Fructus-related herbal medicines frequently have been used in combination with a number of therapeutic drugs for the treatment of various human diseases, such as leukoderma, rheumatism and dysentery. The use of Psoraleae Fructus in combination with drugs has aroused concern of the potential risks of herb-drug interactions (HDI) or herb-endobiotic interactions (HEI). This article reviews the interactions between human drug-metabolizing enzymes and the constituents of Psoraleae Fructus; the major constituents in Psoraleae Fructus, along with their chemical structures and metabolic pathways are summarized, and the inhibitory and inductive effects of the constituents in Psoraleae Fructus on human drug-metabolizing enzymes (DMEs), including target enzyme(s), its modulatory potency, and mechanisms of action are presented. Collectively, this review summarizes current knowledge of the interactions between the Chinese herb Psoraleae Fructus and therapeutic drugs in an effort to facilitate its rational use in clinical settings, and especially to avoid the potential risks of HDI or HEI through human DMEs.
Identification of constituents in Gui-Zhi-Jia-Ge-Gen-Tang by LC-IT-MS combined with LC-Q-TOF-MS and elucidation of their metabolic networks in rat plasma after oral administration

Gui-Zhi-Jia-Ge-Gen-Tang (GZJGGT) is a traditional Chinese medicine (TCM) prescription commonly used to treat cervical spondylopathy, scapulohumeral periarthritis, etc. Though it is widely applied in clinical practice, the effective constituents of GZJGGT remain unclear. This was the first report on the identification of the chemical constituents from GZJGGT in vitro and in vivo using LC-IT-MS combined with LC-Q-TOF-MS. A total of 141 constituents were detected in GZJGGT, and 77 were identified. These compounds mainly included flavonoid glycosides, triterpene saponins, monoterpene glycosides, puerosides, and organic acids. Among them, 12 compounds were unequivocally identified in comparison with reference substances. Additionally, a diagnostic base peak ion filtering strategy for rapid classification of flavonoid O-glycosides and C-glycosides was proposed. After gastrointestinal administration of GZJGGT to rats, 45 prototypes and 48 metabolites in rat plasma were speculated. In addition, the metabolic profile of GZJGGT was portrayed to understand interrelationship between metabolites.
Development of optical-thermal coupled model for phosphor-converted LEDs

In this review, first, we discussed the effect of phosphor features on optical properties by the software simulation in detail. A combination of these parameters: phosphor material, phosphor particle size and particle distribution, phosphor layer concentration, phosphor layer thickness, geometry, and location of the phosphor layer, will result in the final optical performance of the phosphor layer. Secondly, we introduced how to improve light extraction efficiency with various proposed methods. Thirdly, we summarized the thermal models to predict the phosphor temperature and the junction temperature. To stabilize the optical performance of phosphor-converted light emitting diodes (PC-LEDs),much effort has been made to reduce the junction temperature of the LED chips. The phosphor temperature, a critical reliability concern for PC-LEDs, should be attracted academic interest. Finally, we summed up optical-thermal coupled model for phosphors and summarized future optical- thermal issues exploring the light quality for LEDs. We foresee that optical-thermal coupled model for PC-LEDs should be paid more attention in the future.
Physical upgrading plan for slum riverside settlement in traditional area: A case study in Kuin Utara, Banjarmasin, Indonesia

This study aims to draw basic and global concepts for the physical improvement of slum riverside settlements as a fundamental step toward formalizing and securing tenure. Moreover, this work specifies attempts to arrange an upgrading plan derived from the basic strategy for our target location in the traditional settlement of Kuin Utara without failing to recognize its uniqueness and cultural activities. This paper discloses that the basic concept for physical upgrading in a slum settlement consists of three elements: (1) arranging street networks as fundamental systems that structure the settlement, (2) constructing public utility systems that are essential for livelihoods, and (3) providing common space and amenities as "external organs" that form identities and reveal the physical beauty of the location. The proposed infrastructures shall be directed to protect the local cultures and sociocultural activities of the inhabitants. The plan should also be adjusted with respect to the economic constraints in developing countries. Moreover, the improvement strategy for poor housings shall not orientate to modernization merely for beautification without considering the basic aspect: maintaining the dweller's livelihood.
Effects of cultivation strategies on the cultivation of Chlorella sp. HQ in photoreactors

The effects of cultivation strategies (including autotrophic cultivation (AC), heterotrophic cultivation (HC), fed-batch cultivation (FC), heterotrophic + autotrophic two-stage cultivation (HATC), and heterotrophic + mixotrophic two-stage cultivation (HMTC)) on the growth and lipid accumulation of Chlorella sp. HQ and its total nitrogen (TN) and total phosphorus (TP) removal in secondary effluent were investigated in column photoreactors. The results showed that the TN and TP removal rates ranged between 93.72%-95.82% and 92.73%-100%, respectively, under the five different strategies. The microalgal growth potential evaluated by the maximal growth rate (R_(max)) was in the order of HMTC>HC>FC>AC>HATC. The values of biomass, total lipid yield, triacylglycerols (TAGs) yield, and total lipid content of the microalga cultivated in the last 5 d increased significantly, but the TAGs productivities of the five strategies were lower than those in the first 7 d. Compared with all the other cultivation strategies, the TAGs productivity and yield after 12 d of cultivation under the heterotrophic condition reached the highest values accompanying the highest level of intracellular reactive oxygen species (ROS), in which the TAGs yield reached 40.81 mg/L at the end of the cultivation period. The peaks in TAGs yield and ROS level suggested that HC was beneficial for lipids accumulation via regulating the cellular redox status and exerting ROS stress on microalgal cells. In summary, HMTC was the best cultivation strategy for improving the microalgal biomass and HC was the best strategy for microalgal TAGs accumulation to produce biodiesel.
Degradation of antipyrine in the Fenton-like process with a La-doped heterogeneous catalyst

The aim of this study was to synthesize a novel lanthanum (La) doped catalyst and to investigate antipyrine removal in wastewater using the Fenton-like process with the catalyst. The La-doped Co-Cu-Fe catalyst was synthesized using the modified hydrothermal method. Results showed that the La-doped catalyst had higher specific surface area and lower particle size than the catalyst without La doping (i.e., the control) (267 vs. 163 m~2 /g and 14 vs. 32 nm, respectively). Under the conditions of catalyst dosage 0.5 g/L, H_2O_2 concentration 1.70 g/L, and NaHCO]_3 0.1 g/L, the antipyrine removal within 60 min using the Fenton-like process with the La-doped catalyst was much higher than that with the control (95% vs. 54%). The hydroxyl radical concentration with the La-doped catalyst within 60 min was two times higher than that with the control (49.2 vs. 22.1 µg/L). The high catalytic activity of La-doped catalyst was mainly attributed to its high specific surface area based on the X-ray photoelectron spectroscopy result. Our La-doped catalyst should have great potential to remove antipyrine in wastewater using the heterogeneous Fenton-like process.
The delay time of gravitational wave-gamma-ray burst associations

The first gravitational wave (GW)-gamma-ray burst (GRB) association,GW170817/GRB 170817A,had an offset in time,with the GRB trigger time delayed by ~1.7 s with respect to the merger time of the GW signal.We generally discuss the astrophysical origin of the delay time,∆t,of GW-GRB associations within the context of compact binary coalescence (CBC)-short GRB (sGRB) associations and GW burst-long GRB (1GRB) associations.In general,the delay time should include three terms,the time to launch a clean (relativistic) jet,Δt_(jet);the time for the jet to break out from the surrounding medium,Δt_(bo);and the time for the jet to reach the energy dissipation and GRB emission site,Δt_(GRB)·For CBC-sGRB associations,Δt_(jet) and Δ_(tbo) are correlated,and the final delay can be from 10 ms to a few seconds.For GWB-1GRB associations,Δt_(jet) and Δ_(tbo) are independent.The latter is at least ~10 s,so that At of these associations is at least this long.For certain jet launching mechanisms of lGRBs,At can be minutes or even hours long due to the extended engine waiting time to launch a jet.We discuss the cases of GW170817/GRB 170817A and GW150914/GW150914-GBM within this theoretical framework and suggest that the delay times of future GW/GRB associations will shed light into the jet launching mechanisms of GRBs.
Universal scaling law of an origami paper spring

This letter solves an open question of origami paper spring risen by Yoneda et al.(Phys.Rev.E 2019).By using both dimensional analysis and data fitting,an universal scaling law of a paper spring is formulated.The scaling law shows that origami spring force obeys power square law of spring extension,however strong nonlinear to the total twist angle.The study has also successfully generalized the scaling law from the Poisson ratio 0.3 to an arbitrary Poisson's ratio with the help of dimensional analysis.
The FGF metabolic axis

Members of the fibroblast growth factor (FGF) family play pleiotropic roles in cellular and metabolic homeostasis.During evolution,the ancestor FGF expands into multiple members by acquiring divergent structural elements that enable functional divergence and specification.Heparan sulfate-binding FGFs,which play critical roles in embryonic development and adult tissue remodeling homeostasis,adapt to an autocrine/paracrine mode of action to promote cell proliferation and population growth.By contrast,FGF19,21,and 23 coevolve through losing binding affinity for extracellular matrix heparan sulfate while acquiring affinity for transmembrane α-Klotho (KL) or β-KL as a coreceptor,thereby adapting to an endocrine mode of action to drive interorgan crosstalk that regulates a broad spectrum of metabolic homeostasis.FGF19 metabolic axis from the ileum to liver negatively controls diurnal bile acid biosynthesis.FGF21 metabolic axes play multifaceted roles in controlling the homeostasis of lipid,glucose,and energy metabolism.FGF23 axes from the bone to kidney and parathyroid regulate metabolic homeostasis of phosphate,calcium,vitamin D,and parathyroid hormone that are important for bone health and systemic mineral balance.The significant divergence in structural elements and multiple functional specifications of FGF19,21,and 23 in cellular and organismal metabolism instead of cell proliferation and growth sufficiently necessitate a new unified and specific term for these three endocrine FGFs.Thus,the term "FGF Metabolic Axis," which distinguishes the unique pathways and functions of endocrine FGFs from other autocrine/paracrine mitogenic FGFs,is coined.
Effects of temperature and light on seed germination of ephemeral plants in the Gurbantunggut Desert, China: implications for vegetation restoration

Seed germination is a key transitional stage in plant life cycle and is strongly regulated by temperature and light. Therefore, research on the effects of temperature and light on seed germination is extremely meaningful for vegetation restoration, especially in desert ecosystems. Seeds of 28 ephemeral plants collected from the Gurbantunggut Desert of China were incubated at different temperatures (5°C/1°C, 15°C/5°C, 20°C/5°C, 25°C/10°C and 30°C/15°C) in 12-h light/12-h darkness or continuous darkness regimes, and the responses of seed germination to temperature and light and the germination speed were studied in 2016. Results showed that seed germination percentage of the 28 ephemeral plants significantly differed to temperature and light. We classified the studied plants as the following groups based on their responses to temperature: 1 low temperature responsed plants, 12 moderate temperature responsed plants, 7 high temperature responsed plants, 4 non-responsed plants and 5 plants of no germination. It should be noted that Corispermum lehmannianum Bunge is sensitive to both moderate and high temperatures. There were 4 groups of plant in response to light, i.e., 7 light responsed plants, 10 dark responsed plants, 6 light non-responsed plants and 5 plants of no germination. Based on seed germination speed of the 28 ephemeral plants, we divided them into 4 patterns of germination, i.e., very rapid, moderately rapid, moderate and slow. Combining variations of temperature, precipitation and sand dune types in the study area, we suggested that very rapid and moderately rapid germinated plants could be used to moving sand dunes in early spring during vegetation restoration, moderate germinated plants could be used to semi-fixed sand dunes in late autumn, and slow germinated plants could be used to sand plain in summer. Thus, seedling establishment and vegetation restoration would be improved by considering seed germination characteristics of these ephemeral plants in the Gurbantunggut Desert, China.