mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
高强性间歇运动对高血压大鼠血管内皮舒张功能和血压的影响

目的探索不同运动量的高强性间歇游泳运动(HIIS)对高血压(SHR)大鼠抗氧化能力、血管内皮舒张能力和血压的影响。方法将10只WKY大鼠作为正常对照组,将40只SHR大鼠随机分为SHR对照组、小运动量HIIS组(A组)、中等运动量HIIS组(B组)和大运动量HIIS组(C组),运用5组/次、10组/次和20组/次3种运动量分别对A、B和C组进行8 w,5次/w的HIIS干预,分别对干预前、中、后SHR对照组和所有运动组进行血压测试;在干预后对所有组进行抗氧化能力和胸主动脉乙酰胆碱的血管反应测试,对测试结果进行数理分析。结果在抗氧化能力测试中,在8 w的HIIS后,A和B组血清中超氧化物歧化酶(SOD)的数量要显著高于SHR对照组和C组(P<0.05),且A组和B组之间无显著差异(P>0.05);A组和B组的MDA要显著低于SHR对照组和C组,且C组显著高于SHR对照组(P<0.05); 在乙酰胆碱诱导的胸主动脉内皮依赖性舒张反应的测试中,A组和B组乙酰胆碱诱导的胸主动脉内皮依赖性的舒张反应都显著高于C组和SHR对照组,并且B组显著高于A组(P<0.05),SHR对照组显著高于C组(P<0.05); 在血压测试中我们发现,B组的收缩压在每次的测试中均显著低于SHR对照组(P<0.05),其舒张压在第5和第8周的测试中也显著低于SHR对照组(P<0.05)。结论长期中等运动量的HIIS能够有效增强SHR机体的抗氧化能力和血管内皮的舒张能力以及防止其血压的随龄增长,而长期大运动量的HIIS可能会造成SHR的过度疲劳,从而导致其血压随龄升高、血管舒张能力和抗氧化能力的下降。
论极小种群野生植物的研究及科学保护

近年来, 中国在生物多样性保护方面取得了一系列成就, 但由于人类对自然资源的不断索取和全球变化, 一些野生植物仍面临灭绝的风险。目前,仅有1999年国务院批准的《国家重点保护野生植物名录(第一批)》所列种类受到法律的保护。早在20世纪80年代, 我国就引入国际自然保护联盟(IUCN)红色名录的评估体系开展了受威胁物种的评估工作, 先后出版了《中国植物红皮书: 稀有濒危植物》(第一册) (傅立国, 1991)和《中国物种红色名录》(汪松和解焱, 2004), 分别对中国的388种和4,408种植物进行了评估。最近, 中华人民共和国环境保护部和中国科学院又联合发布了《中国生物多样性红色名录: 高等植物卷》评估报告。该报告采用IUCN物种红色名录等级和标准(2001年3.1版)对34,450种高等植物进行了评估, 结果显示有3,767种(约11%)受到不同程度的威胁。尽管当前对受威胁物种等级的划分多参考IUCN的标准, 按照物种种群分布、野外生境和威胁因素等方面的信息来评估推测, 但世界各国如何确定符合本国国情并满足政府决策需求的、急需优先开展系统研究与采取保护行动的类群,无疑还是一个巨大的挑战。
DNA条形码在植物系统发育区系学研究中的应用

达尔文1845年在给虎克的一封信中指出: “地理分布这个伟大的主题几乎是生命规律之基石”(Good, 1953)。探索生物的地理分布格局及其成因是进化生物学家持续不断的追求之一。植物区系的形成是植物在一定的自然历史环境中发展演化和时空分布的综合反映(吴征镒等, 2010)。除了现代气候条件的影响外, 历史过程中可能发生的隔离、分化、扩散和灭绝等进化事件对现代生物地理格局的形成也有重要影响。植物系统发育包含了物种分化、灭绝、分化时间、物种间亲缘关系等进化信息, 因此, 植物区系研究只有与植物系统发育结合, 才能真正揭示进化历史和生态因素等对现代植物区系组成的影响。
前纵隔胸腺囊肿伴炎性假瘤1例

本病需与前上纵隔的非侵袭性胸腺瘤、畸胎瘤等鉴别。非侵袭性胸腺瘤肿块较小时多呈扁平状形态贴于胸骨后区,病变形态规则,边缘光滑清楚,与周围组织、脏器间隙清楚,密度多均匀,增强幅度≥20 HU,无转移及局部组织侵犯等。而纵隔囊肿伴炎性假瘤病变,其肿块实性部分强化明显大于40 HU。前上纵隔畸胎瘤多位于中下前纵隔,发病年龄相对年轻,肿块内成分复杂多样,可表现为囊性、脂肪、钙化(骨骼或者牙齿等)、软组织等不同组织的密度,与本病较易鉴别。
基于信息流增益算法的脑运动功能康复效果评价研究

近年来有学者提出构建主动意愿驱动的脑- 机交互式康复训练方法,这将有助于提高中风后康复训练的效果。研究发现,随着训练的累积,患者的在线准确率逐步提高,然而这并不能直接反映患者自身运动功能的恢复情况。借助于在线记录的脑电图(EEG)数据,通过离线分析,寻找中风患者经康复训练后大脑运动功能康复效果的客观评价参数。为此,使用经典想象运动(MI)作为训练范式。在线分类方法采用广泛认可和使用的共空间模式(CSP)结合线性分类器(LDA)的方法,离线分析方法则采用脑功能连接网络信息流增益地形图来评估大脑运动认知功能的改善。3名正常受试参与实验用于验证在线算法,与中风患者的结果进行对照分析。一名中风后上肢功能障碍患者进行了12 d,连续测试,临床量表显示其训练前后的评分分别为9分和21分。与之相应的分析结果不仅表现在准确率的提高上,信息流增益地形图显示随着训练天数的增加,脑信息交互枢纽位置发生明显迁移,逐渐趋近于正常人的模式,具体表现在从训练前的强偏侧性变为了顶叶集中的模式。该结果提示,基于网络计算得到的信息流增益参数或可作为康复效果客观评价的一种新手段。
Palladium particles from oxime-derived palladacycle supported on Fe_3O_4/oleic acid as a catalyst for the copper-free Sonogashira cross-coupling reaction

An oxime-derived palladacycle was synthesized using 4-bromobenzoxime and pyridine in CHCl_3, and characterized by FT-IR and ~1H NMR spectroscopy. This Pd complex was supported on Fe_3O_4/oleic acid and shown to be an efficient catalyst for the copper-free Sonogashira cross-coupling reaction of various aryl halides with phenylacetylene in air and in ethanol or mixed aqueous medium. The oxime- derived palladacycle gave highly active palladium nanoparticles for the organic synthesis. The coupling products were obtained in high yields with low Pd loading and the heterogeneous catalyst can be separated by an external magnet and reused six times without loss of its activity. The characterization of the catalyst was carried out by XRD, SEM and TEM. Both TEM and XRD revealed that the palladium nanoparticles were well dispersed with diameters from 5 to 10 nm and average size 9.97 nm.
An integrative synchronization and imaging algorithm for GNSS-based BSAR

In this paper, we develop an integrative synchronization and imaging algorithm for bistatic synthetic aperture radar (BSAR) using Global Navigation Satellite Systems as transmitters and a fixed receiver. Due to the lack of a dedicated synchronization link, the usage of navigation signals and the system complexity, traditional synchronization and imaging solutions are not applicable for GNSS-based BSAR. To resolve this problem, this paper focuses on the integrative signal processing algorithm for GNSS-based BSAR. Firstly, to remove the effect of navigation signals, synchronization pre-processing is developed. Then the principle of measuring errors neutralization is theoretically proved by considering the geometric peculiarity of the system. Based on this principle, an integrative synchronization and imaging algorithm is proposed. Finally, the validity of the developed algorithm is confirmed by experimentally obtained data.
Mining pressure monitoring and analysis in fully mechanized backfilling coal mining face–A case study in Zhai Zhen Coal Mine

Fully mechanized solid backfill mining (FMSBM) technology adopts dense backfill body to support the roof. Based on the distinguishing characteristics and mine pressure control principle in this technology, the basic principles and methods for mining pressure monitoring were analyzed and established. And the characteristics of overburden strata movement were analyzed by monitoring the support resistance of hydraulic support, the dynamic subsidence of immediate roof, the stress of backfill body, the front abutment pressure, and the mass ratio of cut coal to backfilled materials. On-site strata behavior measurements of 7403W solid backfilling working face in Zhai Zhen Coal Mine show that the backfill body can effectively support the overburden load, obviously control the overburden strata movement, and weaken the strata behaviors distinctly. Specific performances are as follows. The support resistance decreases obviously; the dynamic subsidence of immediate roof keeps consistent to the variation of backfill body stress, and tends to be stable after the face retreating to 120–150 m away from the cut. The peak value of front abutment pressure arises at 5–12 m before the operating face, and mass ratio is greater than the designed value of 1.15, which effectively ensures the control of strata movement. The research results are bases for intensively studying basic theories of solid backfill mining strata behaviors and its control, and provide theoretical guidance for engineering design in FMSBM.
Replacement of annular domain with trapezoidal domain in computational modeling of nonaqueous-phase-liquid dissolution-front propagation problems

In order to simulate the instability phenomenon of a nonaqueous phase liquid (NAPL) dissolution front in a computational model, the intrinsic characteristic length is commonly used to determine the length scale at which the instability of the NAPL dissolution front can be initiated. This will require a huge number of finite elements if a whole NAPL dissolution system is simulated in the computational model. Even though modern supercomputers might be used to tackle this kind of NAPL dissolution problem, it can become prohibitive for commonly-used personal computers to do so. The main purpose of this work is to investigate whether or not the whole NAPL dissolution system of an annular domain can be replaced by a trapezoidal domain, so as to greatly reduce the requirements for computer efforts. The related simulation results have demonstrated that when the NAPL dissolution system under consideration is in a subcritical state, if the dissolution pattern around the entrance of an annulus domain is of interest, then a trapezoidal domain cannot be used to replace an annular domain in the computational simulation of the NAPL dissolution system. However, if the dissolution pattern away from the vicinity of the entrance of an annulus domain is of interest, then a trapezoidal domain can be used to replace an annular domain in the computational simulation of the NAPL dissolution system. When the NAPL dissolution system under consideration is in a supercritical state, a trapezoidal domain cannot be used to replace an annular domain in the computational simulation of the NAPL dissolution system.
Coupled hydro-mechanical analysis of slope under rainfall using modified elasto-plastic model for unsaturated soils

Two modifications for the basic Barcelona model (BBM) are present. One is the replacement of the net stress by the average skeleton stress in unsaturated soil modeling, and the other is the adoption of an expression for the load–collapse (LC) yield surface that can match flexibly the normal compression lines at different suctions. The predictions of the modified BBM for the controlled-suction triaxial test on the unsaturated compacted clay are presented and compared with the experimental results. A good agreement between the predicted and experimental results demonstrates the reasonability of the modified BBM. On this basis, the coupled processes of groundwater flow and soil deformation in a homogeneous soil slope under a long heavy rainfall are simulated with the proposed elasto-plastic model. The numerical results reveal that the failure of a slope under rainfall infiltration is due to both the reduction of soil suction and the significant rise in groundwater table. The evolution of the displacements is greatly related to the change of suction. The maximum collapse deformation happens near the surface of slope where infiltrated rainwater can quickly reach. The results may provide a helpful reference for hazard assessment and control of rainfall-induced landslides.
Mineralogy and fracture development characteristics of marine shale-gas reservoirs: A case study of Lower Silurian strata in southeastern margin of Sichuan Basin, China

Mineral contents and fractures of shale from well Yuye-1 and outcrops were examined mainly based on systematic description of the cores and outcrops, and data from experimental analyses. The data enabled us to thoroughly explore the mineralogy and developmental features of shale of the Lower Silurian Longmaxi Formation in the study area. The results show that, the Lower Silurian Longmaxi Shale (SLS) in the southeastern margin of Sichuan Basin, China, is primarily characterized by a high content of brittle minerals and a relatively low content of clay minerals. The total content of brittle minerals is approximately 57%, including 27% quartz, 12.2% feldspar, 11.2% carbonate and 2.4% pyrite. The total content of clay minerals reaches 41.6%, composed of illite (23.8%), mixed-layer of illite and smectite (I/S) (10.8%) and chlorite (7.0%). The SLS accommodates the widespread development of various types of fractures, including tectonic fractures, diagenetic fractures, inter-layer fractures and slip fractures. The developmental level of the fracture in the SLS is mainly influenced by faults, lithology, mineral contents and total organic carbon content (TOC) in study area.
A global harmony search algorithm for finding optimal capacitor location and size in distribution networks

Shunt capacitors are broadly applied in distribution systems to scale down power losses, improve voltage profile and boost system capacity. The amount of capacitors added and location of deployment in the system highly determine the advantage of compensation. A novel global harmony search (GHS) algorithm in parallel with the backward/ forward sweep power flow technique and radial harmonic power flow was used to investigate the optimal placement and sizing of capacitors in radial distribution networks for minimizing power loss and total cost by taking account load unbalancing, mutual coupling and harmonics. The optimal capacitor placement outcomes show that the GHS algorithm can reduce total power losses up to 60 kW and leads to more than 18% of cost saving. The results also demonstrate that the GHS algorithm is more effective in minimization of power loss and total costs compared with genetic algorithm (GA), particle swarm optimization (PSO) and harmony search (HS) algorithm. Moreover, the proposed algorithm converges within 800 iterations and is faster in terms of computational time and gives better performance in finding optimal capacitor location and size compared with other optimization techniques.
Adaptive current compensation with nonlinear disturbance observer for single-sided linear induction motor considering dynamic eddy-effect

An adaptive current compensation control for a single-sided linear induction motor (SLIM) with nonlinear disturbance observer was developed. First, to maintain t-axis secondary component flux constant with consideration of the specially dynamic eddy-effect (DEE) of the SLIM, a instantaneously tracing compensation of m-axis current component was analyzed. Second, adaptive current compensation based on Taylor-discretization algorithm was proposed. Third, an effective kind of nonlinear disturbance observer (NDOB) was employed to estimate and compensate the undesired load vibrations, then the robustness of the control system could be guaranteed. Experimental verification of the feasibility of the proposed method for an SLIM control system was performed, and it showed that the proposed adaptive compensation scheme with NDOB could significantly promote speed dynamical response and minimize speed ripple under the conditions of external load coupled vibrations and unavoidable feedback control variables measured errors, i.e., current and speed.
EV71 infection correlates with viral IgG preexisting at pharyngolaryngeal mucosa in children

Enterovirus 71(EV71) infection causes severe central nervous system damage, particularly for children under the age of 5 years old, which remains a major public health burden worldwide. Clinical data released that children may be repeatedly infected by different members in enterovirus and get even worsen. Mucosa, especially epithelium of alimentary canal, was considered the primary site of EV71 infection. It has been elusive whether the preexsiting viral antibody in mucosa plays a role in EV71 infection. To answer this question, we respectively measured viral antibody response and EV71 RNA copy number of one hundred throat swab specimens from clinically confirmed EV71-infected children. The results released that low-level of mucosal Ig G antibody against EV71 broadly existed in young population. More importantly, it further elucidated that the children with mucosal preexsiting EV71 Ig G were prone to be infected, which suggested a former viral Ig G mediated enhancement of viral infection in vivo.
Event-related potential signatures of perceived and imagined emotional and food real-life photos

Although food and affective pictures share similar emotional and motivational characteristics,the relationship between the neuronal responses to these stimuli is unclear. Particularly, it is not known whether perceiving and imagining food and affective stimuli elicit similar event-related potential (ERP) patterns. In this study, two ERP correlates, the early posterior negativity (EPN) and the late positive potential (LPP) for perceived and imagined emotional and food photographs were investigated. Thirteen healthy volunteers were exposed to a set of food photos, as well as unpleasant, pleasant, and neutral photos from the International Affective Picture System. In each trial, participants were first asked to view a photo (perception condition), and then to create a visual mental image of it and to rate its vividness (imagery condition). The results showed that during perception, brain regions corresponding to sensorimotor and parietal motivational (defensive and appetitive) systems were activated to different extents, producing a graded pattern of EPN and LPP responses specific to the photo content - more prominent for unpleasant than pleasant and food content. Also, an EPN signature occurred in both conditions for unpleasant content, suggesting that, compared to food or pleasant content, unpleasant content may be attended to more intensely during perception and may be represented more distinctly during imagery. Finally, compared to LLP activation during perception, as well as imagery and perception of all other content, LPP activation was significantly reduced during imagery of unpleasant photos, suggesting inhibition of unwanted memories. Results are framed within a neurocognitive working model of embodied emotions.
一测多评法测定倍力舒合剂中4种三萜酸的含量

目的建立倍力舒合剂中山楂酸、科罗索酸、齐墩果酸、熊果酸4种三萜酸的一测多评含量测定方法。方法以熊果酸为参照物,建立其与山楂酸、科罗索酸、齐墩果酸的相对校正因子,利用相对校正因子计算样品中这3种三萜酸的含量,同时用外标法测定样品中4种三萜酸的含量,并比较计算值与实测值之间的差异。结果11批样品的实测值与计算值无显著性差异。结论一测多评法可准确测定倍力舒合剂中4种三萜酸的含量,可用于倍力舒合剂的质量控制。
Ultrafast gain dynamics in N_2~+ lasing from highly excited vibrational states pumped by circularly polarized femtosecond laser pulses

We experimentally demonstrate N_2~+ lasing actions at the wavelengths of 353.3, 353.8, and 354.9 nm using a circularly polarized femtosecond laser. The three laser lines correspond to the B~2∑_u~+(u' = 5,4,3) → X~2∑_g~+(v= 4,3,2) transitions, respectively. Particularly, we reveal the pressure-dependent gain dynamics of these lasing actions from highly excited vibrational states with a pump-probe scheme. Our experimental results confirm that electron collisional excitation plays an important role in the establishment of a population inversion of N_2~+ lasing at these wavelengths.
渠县超级杂交中稻"种三产四"丰产工程高产栽培技术

2014年渠县渠南乡李坝村实施超级杂交中稻"种三产四"丰产工程10.93 hm~2,平均产量10.74 t/hm~2,最高达13.32 t/hm~2。总结了其配套高产栽培技术。
水稻温敏核不育系广茉S的异交特性研究

广茉S是以广占63-4S为母本与茉莉新占进行杂交选育而成的籼型水稻温敏核不育系,以广占63-4S为对照,对广茉S的异交特性进行了研究。结果表明,与对照广占63-4S相比,广茉S的单株分蘖数增加2.2个,剑叶长度缩短5.0 cm,穗颈伸出度增加0.8 cm,包颈粒率降低5个百分点,柱头总外露率和花后2~4 d的平均柱头活力分别增加了7.3和8.8个百分点,说明利用广茉S制种有利于提高异交结实率;但由于广茉S当日开花数较广占63-4S分散,且开花高峰时的开花比例比广占63-4S少,因此,利用广茉S制种时要选择适宜的制种基地,正确使用花时调节剂,提高辅助授粉技术,从而提高制种产量。
Th17细胞在妇产科疾病中作用研究进展

T淋巴细胞是人体内免疫系统的重要组成部分,CD4~+T细胞作为效应T细胞的重要成员之一,过去将CD4~+T细胞分为Th1和Th2两类细胞亚群。Th1细胞主要介导细胞免疫,主要分泌白细胞介素2(IL-2)、肿瘤坏死因子β(TNF-αβ)、干扰素γ(IFN-γ)等。其中IFN-γ占主导地位,具有诱导肿瘤细胞凋亡、抑制血管生成,激活抗肿瘤活性的作用。尤其是在细菌、病毒及原虫感染中起保护作用。Th2细胞主要分泌IL-4、IL-5、IL-10和IL-13,介导体液免疫反应。其中IL-4和IL-5起主要作用,其促进B细胞分化、成熟和增殖,为细胞产生抗体。2005年,发现一个不同于Th1/Th2亚群的CD4~+效应T细胞亚群,该亚群细胞分泌IL-17,而不产生IFN-γ和IL-4,因此被命名为Th17细胞亚群,Th17细胞亚群的发现改变了Th1/Th2亚群模式。
腹腔镜技术诊治腹部闭合性损伤研究进展

闭合性腹部损伤是最常见的腹部创伤类型,临床表现多样,病情变化快,极易误诊,而延误治疗可导致严重后果。因此,早期诊断与治疗对于闭合性腹部损伤病人存活及预后尤为重要。近年来,腹腔镜技术不断进步,为其在腹部创伤领域的应用提供了坚实基础,但须满足相应的应用条件。为满足诊断需求该技术应有较高的敏感性和特异性,确保无损伤漏诊,减少不必要的剖腹探查;而在治疗方面,须具有较强的可操作性及合理的手术时间。鉴于不同医疗中心的腹腔镜技术水平各异,能否同时满足上述要求仍有争议。本文结合笔者中心经验及近年文献,系统阐述腹腔镜技术在腹部损伤中使用的禁忌证、适应证、诊断和治疗进展。
双唑草腈原药大鼠亚慢性毒性试验

双唑草腈(Pyracloni)属原卟啉原氧化酶抑制剂,主要作用于水稻田除草用。其作用机制是通过植物神经中元卟啉原氧化酶积累而发挥药效。为了解双唑草腈原药的毒性效应以及可能靶器官,该研究对双唑草腈原药进行了大鼠亚慢性经口毒性试验,求出其亚慢性经口染毒的最大无作用剂量,为其进行长期毒性试验提供毒理学依据。
五味子乙素对两种神经瘤细胞的抑制作用

目的初步探讨不同浓度的五味子乙素(SchB)对人神经母细胞瘤SH-SY5Y细胞及C6胶质瘤细胞生长及增殖的影响。方法体外培养人神经母细胞瘤SH-SY5Y细胞及C6胶质瘤细胞,分别以1 ~ 13 μmol /L SchB作用于SH-SY5Y细胞及C6细胞48 h。倒置显微镜下观察两种肿瘤细胞的形态学及数量变化,四唑盐比色法(MTT法)观察不同浓度的SchB对细胞生长增殖的影响,酶标仪检测各组吸光度。结果与对照组相比,9 ~ 13 μmol /L SchB作用48 h均可引起SH-SY5Y细胞生长增殖抑制,1 ~ 7 μmol /L SchB对SH-SY5Y细胞没有毒性作用;而5 μmol /L SchB即可对C6胶质瘤细胞的生长增殖产生抑制作用。结论SchB对SH-SY5Y细胞及C6胶质瘤细胞的生长增殖均有明显的抑制作用,且C6胶质瘤细胞对SchB的增殖抑制作用更为敏感。
Mechanism and kinetics of the BaMgAl_(10)O_(17):Eu~(2+) alkaline fusion reaction

Knowledge of the kinetics and mechanism of BaMgAl_(10)O_(17):Eu~(2+) (BAM) fusion with sodium hydroxide will benefit recycling rare earth elements (REEs) from the waste phosphors. The reaction temperature range of 290–375 °C and the reaction mechanism were determined using X-ray diffraction, scanning electron microscopy and differential scanning calorimetry. Activation energy was determined by the four model-free methods, and calculated results showed that the Kissinger method value of 579.5 KJ/mol was close to the average value of the Kissinger-Akahira-Sunose (KAS) and the Flynn-Wall-Ozawa (FWO) methods of 563.5 kJ/mol. The calculated activation energy variation tendency versus conversion factor agreed with the proposed mechanism.
Effect of dysprosium substitution on structural and dielectric properties of BiFeO_3-PbTiO_3 multiferroic composites

0.5BiDy_xFe_(1–x)O_3-0.5PbTiO_3(0.5BD_xF_(1–x)-0.5PT) (x=0.00, 0.05, 0.10, 0.15, 0.20) multiferroic composites were prepared by conventional solid state reaction method. Structural characterization was performed by X-ray diffraction and the materials showed tetragonal structure at room temperature. Surface morphology of the composites was studied by a scanning electron microscope (SEM). Frequency and temperature dependence of dielectric constant (ε_r) and dielectric loss (tanδ) of 0.5BD_xF_(1–x)- 0.5PT were measured in a wide range of frequency (100 Hz to 1 MHz) and temperature (25 to 400 oC). The analysis of the study showed that the ε_r and tanδ decreased with increasing frequency in the given range for all the samples which could be explained through the occurrence of dipole relaxation process. The effect of substitution of rare earth element dysprosium (Dy) showed increase in ε_r in all the samples prepared for different concentrations from 0.00 to 0.20. An explanation for high value of ε_r for Dy modified 0.5BiFeO_3-0.5PbTiO_3 (0.5BF-0.5PT) compared to Gd modified 0.5BF-0.5PT was provided. The variation of AC conductivity with inverse temperature found to obey the Arrhenius equation and the composites showed negative temperature coefficient of resistance (NTCR) behavior. The activation energy was found to be in the range from 0.25 to 0.40 eV for all the studied samples.
1-溴丙烷对接触工人神经电生理的影响

目的探讨1-溴丙烷(1-BP)对职业接触者的神经电生理影响。方法选择山东省3个1-BP生产工厂进行职业卫生调查。选取接触1-BP的生产工人54名为接触组,以同厂不接触1-BP的工人42名为对照组,进行神经电生理检查。作业环境中1-BP采用毛细管柱气相色谱法进行检测。结果男性1-BP接触组工人胫神经的运动传导速度为(46.61±3.96)m/s,低于男性对照组[(48.70±3.20)m/s],差异有统计学意义(P<0.05);女性1-BP接触组工人胫神经的运动传导速度为(46.64±6.57)m/s,低于女性对照组[(49.85±4.01)m/s],差异有统计学意义(P<0.05)。结论1-BP可能减慢接触者胫神经的运动传导速度。
清肠化湿方对HT-29细胞IL-6/JAK2/STAT3的影响

溃疡性结肠炎(ulcerative colitis, UC)是一种反复发作的肠道慢性非特异性炎症性疾病,发病机制尚未明确,细胞因子IL-6及其介导的信号通路在非可控性肠道炎症过程中起关键作用。导师沈洪教授所拟清肠化湿方(QHR),治疗轻、中度UC,取得良好效果。课题组前期研究表明该方能调控UC大鼠NF-κB/COX-2通路、PPAR-γ/NF-κB及Toll通路,减少IL-1β、TNF-α等促炎因子分泌,促进抑炎因子IL-10分泌等。本实验在此基础上,以TNF-α、LPS共刺激诱导HT-29细胞炎症模型,观察清肠化湿方对IL-6及其主要信号转导通路之一JAK2/STAT3的影响,进一步探讨其作用机制。
炭药临床应用浅谈

炭药应用于临床历史悠久,从《五十二病方》到清代于诸家方书、本草中皆可发现数量不等的炭类中药。炭药是中药的炮制品之一,然而现代医家大多局限于止血一功。结合现代药理研究,不仅将止血类药物炒炭取其收敛止血之效,还将清热类、补益类、温里类、收涩类等药物炒炭广泛应用于临床,常获良效。
谈医学生涯中部分难忘病例(四十五)

患者血压高、心率快加重心脏缺血,扩大梗死范围,长期咳嗽咯痰,心肌梗死并发急性支气管肺炎、高热、呼吸快、双侧胸水、气胸、胃黏膜出血等多种因素导致循环呼吸衰竭,抢救未成功死亡。
响水涧抽水蓄能电站大型进水球阀安装技术探讨

通过对安徽响水涧抽水蓄能电站进水球阀安装技术的简单探讨,重点介绍了球阀安装过程中的定位和焊接技术,可供以后类似抽水蓄能电站进水球阀安装参考借鉴。
Radiation Parameters of Some Potential Bioactive Compounds

In this study, we aimed to determine the radiation parameters of some potentialbioactive compounds. 1-Aryl-3-dibenzylamino-propane-1-on hydrochloride type Mannich bases were synthesized via classical conventional heating method. Aryl part was changed as phenyl (C_6H_5), 4-methylphenyl (4-CH_3C_6H_4), 4-fluorophenyl (4-FC_6H_4), 4-nitrophenyl (4-NO_2C_6H_4), 4-chlorophenyl (4-ClC_6H_4), 4-bromophenyl (4-BrC_6H_4), and 2-thienyl (C_4H_3S-2-yl). Mass attenuation coefficient (μ_m), effective atomic number (Z_(eff)) and effective electron density (N_(el)) of compounds weredetermined experimentally and theoretically for at 8.040, 8.910, 13.40, 14.96, 17.48, 19.61, 22.16, 24.94, 32.19, 36.38, 44.48, 50.38 and 59.54 keV photon energies by using an HPGe detector with a resolution of 182 eV at 5.9keV. Radiation parameters of these compounds which can be anti-cancer drug candidate were given in the tables. The results show that phenyl ring behave like thiophene ring in terms of radiation absorption. It is thought that the results of study may drive allow the development of drug candidate new compounds in medical oncology.