mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Mapping the hotspots and coldspots of ecosystem services in conservation priority setting

Spatial-explicitly mapping of the hotspots and coldspots is a vital link in the priority setting for ecosystem services (ES) conservation. However, little research has identified and tested the compactness and efficiency of their ES hotspots and coldspots, which may weaken the effectiveness of ecological conservation. In this study, based on the RUSLE model and Getis-Ord Gi* statistics, we quantified the variation of annual soil conservation services (SC) and identified the statistically significant hotspots and coldspots in Shaanxi Province of China from 2000 to 2013. The results indicate that, 1) areas with high SC presented a significantly increasing trend as well, while areas with low SC only changed slightly; 2) SC hotspots and coldspots showed an obvious spatial differentiation-the hotspots were mainly spatially aggregated in southern Shaanxi, while the coldspots were mainly distributed in the Guanzhong Basin and Sand-windy Plateau; and 3) the identified hotspots had the highest capacity of providing SC, with 29.6% of the total area providing 59.7% of the total service. In contrast, the coldspots occupied 46.3% of the total area, but only provided 17.2% of the total SC. In addition to conserving single ES, the Getis-Ord Gi~* statistics method can also help identify multi-functional priority areas for conserving multiple ES and biodiversity.
Dietary n-6:n-3 ratio and Vitamin E improve motility characteristics in association with membrane properties of boar spermatozoa

This study was aimed to evaluate the effects of dietary n-6:n-3 ratio and Vitamin E on the membrane properties and motility characteristics of spermatozoa in boars. Forty Duroc boars were randomly distributed in a 2 × 2 factorial design with two n-6:n-3 ratios (14.4 and 6.6) and two Vitamin E levels (200 and 400 mg kg~(-1)). During 16 weeks of treatment, fresh semen was collected at weeks 0, 8, 12, and 16 for measurements of motility characteristics, contents of fatty acids, membrane properties (membrane fluidity and membrane integrity), and lipid peroxidation of the spermatozoa. The semen was diluted in Beltsville Thawing Solution (BTS) extender and stored at 17°C, and the sperm motility was assessed at 12, 36, 72, and 120 h of storage. The 6.6 n-6:n-3 dietary ratio increased the contents of n-3 polyunsaturated fatty acids (PUFAs) and docosahexaenoic acid (DHA) and improved the membrane integrity and membrane fluidity of the spermatozoa, resulting in notably increased total motility, sperm progressive motility, and velocity parameters of fresh semen. Feeding diet with Vitamin E (400 mg kg~(-1)) prevented sperm lipid peroxidation, and resulted in higher total motility and sperm progressive motility in fresh and liquid stored semen. In conclusion, the adjustment of n-6:n-3 ratio (6.6) and supply of Vitamin E (400 mg kg-1) successfully improved sperm motility characteristics and thus may be beneficial to the fertility of boars, which might be due to the modification of the physical and functional properties of spermatozoa membrane in response to dietary supplementation.
Level of education and mortality after radical prostatectomy

Estimating the risk of competing mortality is of importance in men with early prostate cancer to choose the most appropriate way of management and to avoid over- or under-treatment. In this study, we investigated the impact of the level of education in this context. The study sample consisted of 2630 patients with complete data on level of education (college, university degree, master craftsmen, comparable profession, or others), histopathological tumor stage (organ confined or extracapsular), lymph node status (negative or positive), and prostatectomy specimen Gleason score (<7, 7, or 8-10) who underwent radical prostatectomy between 1992 and 2007. Overall, prostate cancer-specific, competing, and second cancer-related mortalities were study endpoints. Cox proportional hazard models for competing risks were used to study combined effects of the variables on these endpoints. A higher level of education was independently associated with decreased overall mortality after radical prostatectomy (hazard ratio [HR]: 0.75, 95% confidence interval [95% CI]: 0.62-0.91, P = 0.0037). The mortality difference was attributable to decreased second cancer mortality (HR: 0.59, 95% CI: 0.40-0.85, P = 0.0052) and noncancer mortality (HR: 0.73, 95% CI: 0.55-0.98, P = 0.0345) but not to differences in prostate cancer-specific mortality (HR: 1.16, 95% CI: 0.79-1.69, P = 0.4536 in the full model). In conclusion, the level of education might serve as an independent prognostic parameter supplementary to age, comorbidity, and smoking status to estimate the risk of competing mortality and to choose optimal treatment for men with early prostate cancer who are candidates for radical prostatectomy.
Stress analysis model of strip winding system with a sleeve for a coil of thin stainless steel

In a strip winding process, the sleeve is a hollow cylinder that is mounted between a strip coil and a mandrel to maintain uniform coil shape when the strip coil is very thin, but its deformation behavior has not been investigated before. Thus, a finite element (FE) model was presented to calculate the stress distribution in a sleeve and strip coil when 1-3 mm-thick stainless steel was wound around the sleeve. The FE model was developed by extending a previous model by adding a sleeve between the mandrel and strip, and by modifying the boundary and interaction conditions. The strip winding process was divided into an initial process and a steady-state process. During the initial process, the minimum and maximum pressure required on the belt wrapper to maintain coil shape by self-friction of the strip was calculated by the FE model when the belt wrapper is ejected at the end of the initial process. After the initial process, an analytical model of the steady-state process was established to calculate the stress distribution and was compared with the FE model to validate it. The suggested analytical model took 11 s to give the same stress distribution that the FE model took 30 d to produce.
Determining knots by optimizing the bending and stretching energies

For a given set of data points in the plane, a new method is presented for computing a parameter value (knot) for each data point. Associated with each data point, a quadratic polynomial curve passing through three adjacent consecutive data points is constructed. The curve has one degree of freedom which can be used to optimize the shape of the curve. To obtain a better shape of the curve, the degree of freedom is determined by optimizing the bending and stretching energies of the curve so that variation of the curve is as small as possible. Between each pair of adjacent data points, two local knot intervals are constructed, and the final knot interval corresponding to these two points is determined by a combination of the two local knot intervals. Experiments show that the curves constructed using the knots by the new method generally have better interpolation precision than the ones constructed using the knots by the existing local methods.
Assessment of pollution levels and human health risk of heavy metals in dust deposited on Yerevan's tree leaves (Armenia)

The total concentrations of Cd, As, Pb,Cr, Ni, Co, Zn, Cu, Ag, Hg,and Mo were determined in the atmospheric dust of the city of Yerevan by atomic absorption spectrometry (AAnalyst PE 800). Heavy metal pollution levels were evaluated by calculating geo-accu-mulation (I_(geo)) and summary pollution (Z_c) indices. Potential human health risk was assessed using the United States Environmental Protection agency's human health risk assessment model. The results show that mean contents of all elements tested except Ni and Cr were substantially higher than local geochemical background values. According to the I_(geo), Yerevan territory is strongly-to-extremely polluted by As, Ag, Hg, Mo, and Cd. The Z_c assessment indicated that very high pollution was detected in 36 % of samples, high in 32 %, average in 12 %, and low in 20 %. The health risk assessment revealed a non-carcinogenic risk (HI >1) for children at 13 samplings sites and for adults at one sampling site. For children the risk was due to elevated levels of Mo, Cd, Co, and As, while for adults, only Mo. Carcinogenic risk (>1:1,000,000) of As and Cr via ingestion pathway was observed in 25 and 14 samples, respectively. This study, therefore,is the base for further detailed investigations to organize problematic site remediation and risk reduction measures.
Cow manure and cow manure-derived biochar application as a soil amendment for reducing cadmium availability and accumulation by Brassica chinensis L. in acidic red soil

Organic amendment is a promising, in situ phytostabilization approach to alleviate the phytotoxic effects of heavy metal contaminated soils. The aim of this study was to evaluate the feasibility of cow manure (CM) and its derived biochar (CMB) as a soil amendment on cadmium (Cd) availability and accumulation in low and high Cd-accumulating cultivars of Brassica chinensis L. grown in an acidic red soil. CM and CMB were applied to Cd-contaminated acidic red soil at the rates of 0, 3.0 and 6.0% (w/w). Application of CMB was significantly more effective than that of CM, as it reduced the availability of Cd in soil by 34.3-69.9% and its bioaccumulation in the low Cd accumulator, Aijiaoheiye 333, by 51.2 and 67.4%, respectively. The addition of CMB significantly increased the extractability and accumulation of trace metals (Zn, Mn, Fe, and Cu) by plants and improved plant biomass production. CMB application, combined with utilizing low Cd accumulating cultivars represents a new, sustainable strategy to alleviate the toxic effects on Cd and improve food safety.
Fine mapping of powdery mildew resistance gene PmTm4 in wheat using comparative genomics

Powdery mildew, caused by Blumeria graminis f. sp. tritici, is one of the most severe wheat diseases. Mining powdery mildew resistance genes in wheat cultivars and their appliance in breeding program is a promising way to control this disease. Genetic analysis revealed that a single dominant resistance gene named PmTm4 originated from Chinese wheat line Tangmai 4 confers resistance to prevailing isolates of B. graminis f. sp. tritici isolate E09. Detailed comparative genomics analyses helped to develop closely linked markers to PmTm4 and a fine genetic map was constructed using large F2 population, in which PmTm4 was located into a 0.66-cM genetic interval. The orthologous subgenome region of PmTm4 in Aegilops tauschii was identified, and two resistance gene analogs (RGA) were characterized from the corresponding sequence scaffolds of Ae. tauschii draft assembly. The closely linked markers and identified Ae. tauschii orthologs in the mapping interval provide an entry point for chromosome landing and map-based cloning of PmTm4.
Photoemission cross section: A critical parameter in the impurity photovoltaic effect

A numerical study has been conducted to explore the role of photoemission cross sections in the impurity photovoltaic(IPV)effect for silicon solar cells doped with indium. The photovoltaic parameters(short-circuit current density, opencircuit voltage, and conversion efficiency)of the IPV solar cell were calculated as functions of variable electron and hole photoemission cross sections. The presented results show that the electron and hole photoemission cross sections play critical roles in the IPV effect. When the electron photoemission cross section is < 10~(-20)cm~2, the conversion efficiency η of the IPV cell always has a negative gain(?h < 0)if the IPV impurity is introduced. A large hole photoemission cross section can adversely impact IPV solar cell performance. The combination of a small hole photoemission cross section and a large electron photoemission cross section can achieve higher conversion efficiency for the IPV solar cell since a large electron photoemission cross section can enhance the necessary electron transition from the impurity level to the conduction band and a small hole photoemission cross section can reduce the needless sub-bandgap absorption. It is concluded that those impurities with small(large)hole photoemission cross section and large(small)electron photoemission cross section, whose energy levels are near the valence(or conduction)band edge, may be suitable for use in IPV solar cells. These results may help in judging whether or not an impurity is appropriate for use in IPV solar cells according to its electron and hole photoemission cross sections.
Femtosecond laser induced nanostructuring of zirconium in liquid confined environment

The surface, structural, and mechanical properties of zirconium after irradiation with Ti: sapphire laser(800 nm, 30 fs, 1 kHz)have been investigated. The zirconium targets were exposed for a varying number of laser pulses ranging from 500 to 2000 at a fixed fluence of 3.6 J/cm~2 corresponding to an intensity of 1.2×10~(14)W/cm~2 in ambient environments of deionized water and propanol. A scanning electron microscope(SEM)was employed to investigate the surface morphology of the irradiated zirconium. The SEM analysis shows the formation of various kinds of features including nanoscale laser induced periodic surface structures(LIPSS), sponge like surface structure, flakes, conical structures, droplets, pores, and cavities. The energy dispersive x-ray spectroscopy(EDS)analysis exhibits the variation in chemical composition along with an enhanced diffusion of oxygen under both ambient conditions. The crystal structure and phase analyses of the exposed targets were explored by x-ray diffraction(XRD)and Raman spectroscopy techniques, respectively. The XRD analysis confirms the presence of various phases of zirconium hydride and zirconia after ablation in both de-ionized water and propanol. However, excessive hydrides are formed in the case of propanol. The Raman analysis supports the EDS and XRD results. It also reveals the presence of oxides(zirconia)after irradiation in both de-ionized water and propanol environments. The chemical reactivity of zirconium was significantly improved in the presence of liquids which were accountable for the growth of novel phases and modification in the chemical composition of the irradiated Zr. A nanohardness tester was employed to measure the nanohardness of the laser treated targets. The initial increase and then decrease in nanohardness was observed with an increase in the number of laser pulses in the de-ionized water environment. In the case of propanol, a continuous decrease in hardness was observed.
Electron localization of H_2~+ in a dc electric field

A dc electric field is utilized to steer the electron motion after the molecular ion H_2~+ is excited by an ultrashort ultraviolet laser pulse. The numerical simulation shows that the electron localization distribution and the dissociation control ratio are dependent on the polarization direction and amplitude of the dc electric field. Most electrons of the dissociation state move opposite to the dc electric field and stabilize at the dressed-up potential well, for the dressed-down well is occupied by the electrons of the 1sσ_g state.
Neuroprotective properties of dietary saffron: more than just a chemical scavenger?

There is increasing evidence that consumption of saffron, a spice derived from the flower of the Crocus savitus plant, has various therapeutic effects, including protection of the central nervous system. These beneficial effects have been widely attributed to the strong antioxidant properties of saffron and its key constituents, although data showing that these antioxidative properties are potentiated by the presence of living cells (Ordoudi et al., 2009) suggest actions that extend beyond direct chemical scavenging. One recent study (Skladnev et al., 2016) has provided evidence that dietary saffron can modulate the brain transcriptome, up-regulating specific stress-inducible pathways - coupled with the observation that saffron exhibits a non-linear dose-response relationship, these findings suggest that saffron, like other phytochemicals, might exert its neuroprotective effects by acting as a mild biological stressor.
The cortical activation pattern during bilateral arm raising movements

Bilateral arm raising movements have been used in brain rehabilitation for a long time. However, no study has been reported on the effect of these movements on the cerebral cortex. In this study, using functional near infrared spectroscopy (fNIRS), we attempted to investigate cortical activation generated during bilateral arm raising movements. Ten normal subjects were recruited for this study. fNIRS was performed using an fNIRS system with 49 channels. Bilateral arm raising movements were performed in sitting position at the rate of 0.5 Hz. We measured values of oxyhemoglobin and total hemoglobin in five regions of interest: the primary sensorimotor cortex, premotor cortex, supplementary motor area, prefrontal cortex, and posterior parietal cortex. During performance of bilateral arm raising movements, oxyhemoglobin and total hemoglobin values in the primary sensorimotor cortex, premotor cortex, supplementary motor area, and prefrontal cortex were similar, but higher in these regions than those in the prefrontal cortex. We observed activation of the arm somatotopic areas of the primary sensorimotor cortex and premotor cortex in both hemispheres during bilateral arm raising movements. According to this result, bilateral arm raising movements appeared to induce large-scale neuronal activation and therefore arm raising movements would be good exercise for recovery of brain functions.
Characterization of Leaf Transcriptome in Banksia hookeriana

Banksia is a significant element in vegetation of southwestern Australia, a biodiversity hotspot with global significance. In particular, Banksia hookeriana represents a species with significant economic and ecological importance in the region. For better conservation and management, we reported an overview of transcriptome of B. hookeriana using RNA-seq and de novo assembly. We have generated a total of 202.7 million reads (18.91 billion of nucleotides) from four leaf samples in four plants of B. hookeriana, and assembled 59,063 unigenes (average size = 1098 bp) through de novo transcriptome assembly. Among them, 39,686 unigenes were annotated against the Swiss-Prot, Clusters of Orthologous Groups (COG), and NCBI non-redundant (NR) protein databases. We showed that there was approximately one single nucleotide polymorphism (SNP) per 5.6-7.1 kb in the transcriptome, and the ratio of transitional to transversional polymorphisms was approximately 1.82. We compared unigenes of B. hookeriana to those of Arabidopsis thaliana and Nelumbo nucifera through sequence homology, Gene Ontology (GO) annotation, and KEGG pathway analyses. The comparative analysis revealed that unigenes of B. hookeriana were closely related to those of N. nucifera. B. hookeriana, N. nucifera, and A. thaliana shared similar GO annotations but different distributions in KEGG pathways, indicating that B. hookeriana has adapted to dry-Mediterranean type shrublands via regulating expression of specific genes. In total 1927 potential simple sequence repeat (SSR) markers were discovered, which could be used in the genotype and genetic diversity studies of the Banksia genus. Our results provide valuable sequence resource for further study in Banksia.
心脏肉瘤致多浆膜腔积液并CA125升高一例

心脏肿瘤常无特异临床症状,因肿瘤的位置及对周围组织浸润出现如呼吸困难、胸痛、胸闷、心悸、低热、栓塞、乏力等非特异性症状。以多浆膜腔积液为主要表现的病例较少见,现报道1例以多浆膜腔积液为主要表现的心脏梭形细胞肉瘤。
Liraglutide directly protects cardiomyocytes against reperfusion injury possibly via modulation of intracellular calcium homeostasis

Background Liraglutide is glucagon-like peptide-1 receptor agonist for treating patients with type 2 diabetes mellitus. Our previous studies have demonstrated that liraglutide protects cardiac function through improving endothelial function in patients with acute myocardial infarction undergoing percutaneous coronary intervention. The present study will investigate whether liraglutide can perform direct protective effects on cardiomyocytes against reperfusion injury. Methods In vitro experiments were performed using H9C2 cells and neonatal rat ventricular cadiomyocytes undergoing simulative hypoxia/reoxygenation (H/R) induction. Cardiomyocytes apoptosis was detected by fluorescence TUNEL. Mitochondrial membrane potential (ΔΨm) and intracellular reactive oxygen species (ROS) was assessed by JC-1 and DHE, respectively. Fura-2/AM was used to measure intracellular Ca~(2+) concentration and calcium transient. Immunofluorescence staining was used to assess the expression level of sarcoplasmic reticulum Ca~(2+)-ATPase (SERCA2a). In vivo experiments, myocardial apoptosis and expression of SERCA2a were detected by colorimetric TUNEL and by immunofluorescence staining, respectively. Results In vitro liraglutide inhibited cardiomyotes apoptosis against H/R. ΔΨm of cardiomyocytes was higher in liraglutide group than H/R group. H/R increased ROS production in H9C2 cells which was attenuated by liraglutide. Liraglutide significantly lowered Ca~(2+) overload and improved calcium transient compared with H/R group. Immunofluorescence staining results showed liraglutide promoted SERCA2a expression which was decreased in H/R group. In ischemia/reperfusion rat hearts, apoptosis was significantly attenuated and SERCA2a expression was increased by liraglutide compared with H/R group. Conclusions Liraglutide can directly protect cardiomyocytes against reperfusion injury which is possibly through modulation of intracellular calcium homeostasis.
西部创伤协会关于血流动力学不稳定骨盆骨折处理的重要决定——2016年更新

自从2008年西部创伤学会(Western Trauma Association)发布关于血流动力学不稳定骨盆骨折处理指南后,到目前为止,总体治疗方案并未有重大变化,但是一些细节,在最近几年讨论较多,此次更新为中期更新,现将主体内容翻译如下:
从经络视角解读NEI网络对骨质疏松症的调控作用

NEI网络的调控在骨质疏松发生机制中有重要的作用,近年来,中医药治疗骨质疏松症显示出其特殊的优势,治疗本病使用频次最多的中药以归经为肾、肝、脾三条经络为主,基于中医学整体观念及经络学说中“经络所通、主治所及”的治疗准则,再联系三条经络的循行路径,这三条经能够关联到NEI网络中与本病密切相关的部分(中枢神经系统、免疫系统以及甲状腺、甲状旁腺、胸腺、肾上腺等内分泌腺)。而相关药物的现代研究也证实归经为这三条经的药物能够通过调控NEI网络中下丘脑-垂体-靶腺(性腺、肾上腺、甲状腺)轴的许多信息物质,实现对机体骨代谢的调控。由此可从经络的视角来解读NEI网络在骨质疏松症发生机制中的调控作用。
基于中医传承辅助平台探讨丁学屏名中医诊治糖尿病合并肥胖的临证经验及用药规律研究

目的运用"中医传承辅助平台管理系统(V2.5)",分析“疾病-证候-治法-中药”之间的关系,探讨丁学屏教授诊治糖尿病合并肥胖的临证经验及用药规律,总结丁学屏教授学术经验。方法通过临床医案采集,结合软件的分析系统,采用频次统计法,统计得出医案症状、证候、治法出现频次,使用中药性味归经频次;采用关联规则分析法、聚类分析法、改进的互信息法、复杂系统熵聚类、无监督的熵层次聚类等高级数据挖掘方法,统计得出处方中药物组合使用频次及药物之间的关联规则。结果本研究对13例糖尿病合并肥胖脾胃湿热证进行分析,高频药物有黄连,地骨皮,土牛膝,土茯苓,莪术等;药物组合有“黄连,土茯苓”“黄连,地骨皮”“黄连,莪术”“黄连,土牛膝”“ 土茯苓,土牛膝”“黄连,土茯苓,土牛膝” “莪术,郁金”等。结论辨治糖尿病合并肥胖,从湿、热、瘀、浊着手,治以清热祛湿,疏瘀化浊。
针刺配合静帅康胶囊治疗儿童抽动秽语综合征疗效观察

目的观察针刺配合静帅康胶囊治疗儿童抽动秽语综合征的治疗效果。方法将患儿38例分为两组,治疗组19例用针刺、静帅康胶囊口服,对照组19例只用针刺治疗,比较两组疗效。结果治疗3月后,统计总有效率治疗组94.73%, 对照组68.42%。两组比较有统计学意义(P<0.05)。结论采用针刺配合中成药静帅康胶囊口服治疗儿童抽动秽语综合征疗效明显。
清湿化瘀法对子宫腺肌病小鼠雌激素效应因子PTEN、P-P65的时空变化影响

目的在以清湿化瘀为治法的内异康复片被广泛应用于治疗子宫腺肌病(AM)和前期实验研究的基础上,运用同种异体垂体植入子宫的方法建立AM实验模型,采用免疫组化的技术检测PTEN、P-P65在AM治疗前后各组小鼠在位及异位子宫内膜上的表达差异,探究AM的发病机制。方法采用异体垂体移植法造模,随机设内异康复片低、中、高剂量组,孕三烯酮组,丹莪妇康煎膏组,模型组。饲养3月后分别灌胃3月治疗,免疫组化法观察治疗前后在位、异位子宫内膜上PTEN、P-P65差异。结果不同方法治疗后PTEN表达均增高,显著高于模型组(P<0.001),内异康复片高剂量组优于其他各治疗组(P<0.001);P-P65表达均下降,显著低于模型组(P<0.001),内异康复片高剂量组优于其他各治疗组(P<0.001)。结论内异康复片可上调PTEN,下调P-P65的表达,从而达到控制和治疗子宫腺肌病及其临床症状的目的。
高血糖对胰腺癌患者神经浸润及预后的影响

胰腺癌患者预后差。有研究认为,到2030年,胰腺癌将成为排名第二的致死性肿瘤。根治性手术切除是唯一可治愈胰腺癌的方法。然而,在胰腺癌确诊时只有15%~25%的患者具有根治性手术切除的机会。嗜神经浸润是胰腺癌生物学特性之一,与其不良预后有关。糖尿病与胰腺癌发生发展及预后密切相关。本研究回顾性分析了79例接受胰腺癌根治手术治疗的胰腺癌患者临床与随访资料,探讨了高血糖对胰腺癌神经浸润及预后的影响。