mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Hot workability of Mg-9Y-1MM-0.6Zr alloy

The behavior evolvement of Mg-9Y-lMM-0.6Zr (WE91)alloy during hot deformation process was discussed.The flow stress behavior of magnesium alloy over the strain rate range of 0.001 to 1 s~(-1)and the temperature range of 653 to 773 K was studied on a Gleeble-1500D hot simulator under the maximum deformation degree of 60%.The experimental results showed that the relationship between stress and strain was obviously affected by the strain rate and deformation temperature and the flow curves observed were typical of the occurrence of dynamic recrystallization.The flow stress of WE91 magnesium alloy during high temperature deformation could be represented by the Zener-Hollomon parameter in the hyperbolic Arrhenius-type equation.The average deformation activation energy Q and strain coefficient n were 224.11 kJ/mol and 3.08 by calculation,respectively.The processing maps were calculated and analyzed according to the dynamic materials model.The map at strain of 0.916 exhibited three domains with peak efficiency of 49%,44% and 42%,respectively.It was found that the alloy could be extruded at 693 K with mechanical properties of σ0.2=240 MPa,σb=3 15 MPa and = 15.5%.
Global rare earth resources and scenarios of future rare earth industry

It is known to all that China is abundant in rare earth resources. But rare earth deposits are really not that rare in the earth crust. In the five continents, i.e. Asia, Europe, Australia, North and South America, and Africa, there are about thirty four countries found to have rare earth deposits; Brazil might surpass China and rank the first in rare earth deposits. At present, investment in rare earth production was surged, there have been about 200 projects, and the total production for 25 of them would be more than 170 thousand tons after 2015, a multi-supply system on rare earths is being established worldwide. Cautions on the investment of rare earth production are involved
Effect of copper impurity on the optical loss and Nd3+ nonradiative energy loss of Nd-doped phosphate laser glass

N31-type phosphate laser glasses doped with different concentrations of Cu were prepared.Their optical loss coefficient at 1053 nm wavelength and nonradiative transition rate from the Nd3+ 4F3/2 state were determined and analyzed in detail.The optical loss coefficient per unit of Cu2+ (cm~(-1)/ppmw)and the fluorescence decay rate (Hz/ppmw)caused by Cu2+ and Nd3+ interaction were 0.0024 and 7.9,respectively.Cu impurity affected both optical loss at 1053 nm and fluorescent emission of Nd3+ 4F3/2 state seriously in N31 laser glass.
Morphology of NaNdF4 nanocrystals from Nd(C3H7COO)_3·Phen and Nd(NO_3)_3·Phen (Phen, 1,10-phenanthroline) as neodymium precursors

A series of NaNdF4 nanocrystals was synthesized via a facile hydrothermal route with Nd(C_3H_7COO)_3·Phen and Nd(NO_3)_3·Phen(Phen, 1,10-phenanthroline) as the Nd precursors. Distinct effect of the neutral donor ligand (Phen) on the morphology of NaNdF4 nanocrystals was demonstrated. When Nd(C_3H_7COO)_3·Phen was chosen and the hydrothermal reaction temperature was controlled at 220 ℃, the NaNdF4 nanocrystals with uniform short nanorod shape were obtained. The sizes of the as-prepared nanorods could be tuned by changing the hydrothermal temperatures. This method provided a useful way for the preparation of sodium rare-earth fluoride nanocrystals with controlled shapes and sizes
EXPERIMENTAL INVESTIGATION OF CAVITATION IN A SUDDEN EXPANSION PIPE

For sudden expansion pipes,experiments were carried out to study the cavitation inception for various enlargement ratios in high speed flows.The flow velocity of the prototype reaches 50 m/s in laboratory.The relationship between the expansion ratio and the incipient cavitation number is obtained.The scale and velocity effects are revealed.It is shown that Keller’s revised formula should be modified to calculate the incipient cavitation number when the forecasted velocity of the flows in the prototype exceeds the experimental velocity.
Synthesis,structure and photoluminescent properties of a new Eu(III)complex with 5-bromoisophthalic acid

The self-assembly of 5-bromoisophthalic acid (H2BIPA)with Eu(NO3)36H20 under the hydrothermal conditions gave a 3D coordination polymer,Eu2(BIPA)3(CH3CH20H)(1),which was characterized by elemental analysis,IR and single-crystal X-ray diffraction.Complex 1 displayed an unusual three-dimensional network of a rare (4,6)-connected (4~8.6~6.8)2(4~4.6~2)2(4~2.8~4)topology,which was different from Eu2(BDC)3(H20)2 (BDC=isophthalate),because the -Br substituent of the isophthalate resulted in the different electronic effects and the steric hindrance to change the coordination modes of carboxylate groups in the assembled process.Moreover,the luminescent properties of 1 were also investigated in the solid state.
Breast Fibromatosis after Hydrophilic Polyacrylamide Gel Injection for Breast Augmentation:a Case Report and Review of the Literature

BREAST fibromatosis is a rare kind of lesion.The average incidence is about 2-4 per million every year.1 So far there have been about 100 cases reported altogether.2 In this report,we describe a case of breast fibromatosis developed after hydrophilic polyacrylamide gel(HPG)injection for breast augmentation.By reviewing the literature,the possible pathogenesis of this case and the proper treatment strategy are investigated.
First 30 endobronchial ultrasound-guided transbronchial needle aspirations:a single institution's early experience

Background A new technique developed in 2002,real time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA),has been one of the most important tools in lymph nodes (LNs)staging before lung cancer surgery.EBUS-TBNA was introduced into China in 2008.Methods Between June 2009 and October 2009,30 patients with mediastinal/hilar lymphadenopathy and thoracic masses previously detected with CT scan underwent EBUS-TBNA without rapid onsite cytological examination.Results From 30 patients,33 samples were obtained from LNs and seven samples from intrapulmonary lesions.Twenty out of the 23 lung cancer diagnoses were clarified through the procedure,with sensitivity,specificity,positive predictive value,negative predictive value and accuracy being 87%,100%,100%,70% and 90%,respectively.All three false negative cases were found in the first five procedures.Additionally,among the 33 LNs examined,three specimens that had no lymphocytes were also found within the first five procedures.There were no major complications,and the procedures were uneventful.Conclusions EBUS-TBNA seems a safe and effective technique in making diagnosis for mediastinal/hilar LNs and intrapulmonary masses.For pulmonologists experienced in bronchoscopy,the sensitivity of the procedure for diagnosing lung cancer should be no less than 90% after the initial five procedures .
Detection of neural stem cells function in rats with traumatic brain injury by manganese-enhanced magnetic resonance imaging

Background Previously we had successfully tracked adult human neural stem cells (NSCs)labeled with superparamagnetic iron oxide particles (SPIOs)in host human brain after transplantation in vivo non-invasively by magnetic resonance imaging (MRI).However,the function of the transplanted NSCs could not be evaluated by the method.In the study,we applied manganese-enhanced MRI (ME-MRI)to detect NSCs function after implantation in brain of rats with traumatic brain injury (TBI)in vivo.Methods Totally 40 TBI rats were randomly divided into 4 groups with 10 rats in each group.In group 1,the TBI rats did not receive NSCs transplantation.MnCI24H20 was intravenously injected,hyperosmolar mannitol was delivered to disrupt rightside blood brain barrier,and its contralateral forepaw was electrically stimulated.In group 2,the TBI rats received NSCs (labeled with SPIO)transplantation,and the ME-MRI procedure was same to group 1.In group 3,the TBI rats received NSCs (labeled with SPIO)transplantation,and the ME-MRI procedure was same to group 1,but diltiazem was introduced during the electrical stimulation period.In group 4,the TBI rats received phosphate buffered saline (PBS)injection,and the ME-MRI procedure was same to group 1.Results Hyperintense signals were detected by ME-MRI in the cortex areas associated with somatosensory in TBI rats of group 2.These signals,which could not be induced in TBI rats of groups 1 and 4,disappeared when diltiazem was introduced in TBI rats of group 3.Conclusion In this initial study,we mapped implanted NSCs activity and its functional participation within local brain area in TBI rats by ME-MRI technique,paving the way for further pre-clinical research.
Hereditary benign telangiectasia without family history in China

A case of hereditary benign telangiectasia without family history was reported. A 39-year-old woman presented with small and tiny telangiectases on the face, neck, upper trunk and forearms at birth. The numbers and sizes of the lesions increased gradually and she had no hemorrhagic diathesis and systemic diseases. No similar patients were found in her family. Upon physical examination, telangiectases were found on the face, neck, upper trunk and forearms; and a telangiectatic erythema was found on the right forearm 25 mm x 40 mm in size. Histopathology examination showed a normal epidermis and dilation of the capillaries at upper dermis. Hereditary benign telangiectasia without family history was diagnosed
Self-monitoring of blood glucose improved glycaemic control and 10-year coronary heart disease risk profile of type 2 diabetic patients

Background The debate over the overall benefits of self-monitoring of blood glucose in type 2 diabetes patients is still continuing. We aimed to assess the difference in glycaemic control and coronary heart disease (CHD) risk levels of experimental type 2 diabetes patients provided with facilities for self-monitoring blood glucose and their counterparts without such facilities. Methods Sixty-one patients who had no prior experience in using glucometers were studied as intervention (n=30) and control (n=31) groups. The intervention group was trained in self-monitoring of blood glucose and documentation. Baseline blood glucose and fasting blood glucose were measured and the intervention patients were provided with glucometers and advised to self-monitor their fasting and postprandial blood glucose over six months. The 10-year CHD risk levels were determined with the United Kingdom Prospective Diabetes Study-derived risk engine calculator. Results The age and diabetes duration were similar in the two groups (P >0.05). The majority of the patients were unemployed or retired females with only a primary level education. After 3 months, the haemogolbin Aic (HbAic) levels of the control patients remained unchanged ((7.8±0.3)% vs. (7.9±0.4)%, P >0.05) whereas the HbA1c levels of the intervention patients were significantly reduced from the baseline at three ((9.6±0.3)% vs. (7.8±0.3)%, P<0.001) and six ((9.2±0.4)% vs. (7.5±0.3)%, P <0.001) months. Interestingly, while the 10-year CHD risk level of the control group remained unchanged after three months, that of the intervention group was remarkably reduced at three and six months from the baseline level ((7.4±1.3)% vs. (4.5±0.9)%, P=0.056). Conclusion Self-monitoring of blood glucose in type 2 diabetes patients significantly improved glycaemic control and the CHD risk profile, suggesting that type 2 diabetes patients will potentially benefit from inclusion of glucose meters and testing strips in their health-care package
Semi-mature MyD88-silenced bone marrow dendritic cells prolong the allograft survival in a rat model of intestinal transplantation

Background Semi-mature dendritic cells (DCs) may induce tolerance rather than immunity. However, little is known about the regulatory mechanism by which these DCs induce transplant tolerance. Myeloid differentiation factor 88 (MyD88) is a key adaptor of Toll-like receptor signaling, which plays a critical role in DC maturation. Activation of MyD88-silenced immature DCs results in the generation of semi-mature DCs. We explored the possibility of using these DCs to induce intestinal transplant tolerance in rats. Methods MyD88 expression was silenced in bone marrow DCs (F344 rats) using small interfering RNAs for 24 hours, at which point, lipopolysaccharide (LPS) was added to the culture for another 48 hours. These cells were analyzed for their in vitro and in vivo tolerizing capacities. Results Semi-mature DCs expressing moderate levels of MHC class II and low levels of co-stimulatory molecules were found to produce interleukin (IL)-10, while IL-12 production was decreased. In vitro co-culture with completely allogeneic T cells from Wistar rats led to a significant decrease in alloreactive T-cell responses. In vivo, the transfer of semi-mature DCs (1x10~6 cells) followed by the transplantation of fully mismatched intestinal grafts (F344 rats) led to significantly prolonged survival compared to rats receiving immature and mature DCs. Serum from semi-mature DC-treated rats contained lower concentrations of the pro-inflammatory cytokines IL-2 and interferon-y 5 days after transplantation. Conclusion Semi-mature DCs may promote inducible allograft tolerance and this study suggests a new strategy by which to facilitate the induction of transplant tolerance
Beneficial effects of autologous bone marrow mononuclear cell transplantation against ischemic bile duct in rats

Background Bone marrow cell transplantation has been shown to induce angiogenesis and thus improve ischemic disease. This study evaluated the effect of bone marrow mononuclear ceil (BM-MNCs) implantation on neovascularization in rats with ischemic bile duct. Methods We established an animal model for ischemic biliary stenosis by clamping manipulation. There were 10 rats in each group: BM-MNCs implantation group, control group and normal group. Rat femur BM-MNCs were isolated using density gradient centrifugation. BM-MNCs or phosphate buffered saline were injected into three points around bile duct tissue in the three groups (25 μl/point). Control rats received injections of saline under similar conditions. At the 21 days after operation, cholangiography was performed. Differentiation of the engrafted cells and capillary density in the bile duct were analyzed by immunohistochemical staining. Results Engrafted cells could differentiate into endothelial cells. The stricture rate in the implantation group was 40%, significantly lower than that in the control group (100%). The capillary density in the implantation group was significantly higher than in the control group or the normal group. Conclusions The implantation of BM-MNCs induced neovascularization in the ischemic bile duct. It improved the blood supply of the ischemic bile duct to prevent or decrease biliary ischemic stricture
Effect of p21Ras in vitro intervention on the phenotype of airway smooth muscle cells from asthmatic rats

Background An important physiological feature of asthma is the phenotypic change of airway smooth muscle cells (ASMCs), but the precise mechanisms behind the ASMCs' change remains unknown. Our study assessed whether p21 Ras can directly modulate the phenotype of ASMCs. Methods Rat ASMCs were treated with FTP Ill, a highly specific p21Ras inhibitor. ASMCs were identified via immunocytochemistry. The ultrastructure of cells was observed by electron microscopy, and the expression of a-actin was evaluated by Western blotting analysis. The levels of IL-6 and RANTES were measured by enzyme linked immunosorbent assay (ELISA). Results It was observed that ASMCs in asthma exhibited a proliferative/secretory phenotype and were larger, denser and had many pseudopods, as well as increased signs of secretory organelles. Additionally, the level of a-actin, a marker of ASMCs, was reduced in asthmatic ASMCs and the secretion of IL-6 and RANTES was increased. When FTP III was added to asthmatic ASMCs it induced a contractile phenotype, with increased a-actin levels and reduced secretion of IL-6 and RANTES. Conclusions It appears that p21 Ras induces asthmatic ASMCs to a proliferative/secretory phenotype, but its inhibitor FTP III, can significantly reverse this phenotype. The role of p21Ras in the ASMCs may be a new target for asthma treatment
Clinical evaluation of the quantitative locator for conjunctiva resection used as an instrument for the treatment of conjunctivochalasis

Background The crescent excision of the inferior bulbar conjunctiva has been advised as a surgical procedure in the management of conjunctivochalasis refractory to medical treatments.However,it is difficult for this procedure to design how much conjunctival tissue should be excised.This study aimed to present a quantitative locator for conjunctiva resection and evaluate its effect on the treatment of conjunctivochalasis (CCh).Methods Poly β-hydroxyethyl methacrylate resin/β-hydroxyethyl methacrylate (HEMA,water gel)was used as the material to make the quantitative locator which was designed to suit the specific patient.Forty-six patients with bilateral symptomatic CCh were included in this prospective study.Of the patients,while the right eye underwent the popularly used crescent-shaped conjunctiva resection (group I),the left eye was treated with conjunctiva resection assisted by the quantitative locator (group II).International Ocular Surface Disease Index (OSDI),scores of remnant conjunctiva fold,complications and conjunctival cut healing,height of tear meniscus,tear break-up time (BUT),and time of surgery were evaluated.Tasting chloromycetin test (TCT)was used to evaluate how the lacrimal duct worked.Results OSDI in group 11 (8.82±2.36)was significantly lower than that in group I (14.67±2.21)(t=12.22,P <0.01).The amount of conjunctiva fold remaining in group II was less than that in group I.Scores of remnant conjunctiva fold in group I were significantly higher than those in group II (t=31.85,P <0.01).While evaluation scores of conjunctival cut healing in group I were lower than those in group II,scores of complication in group I were significantly higher than those in group II at 8 weeks after surgery (t=89.60,P <0.01).There was no significant difference in eyes with normal BUT (X2=0.031,P=0.985)between the two groups,as the case was in eyes with positive TCT (X2=0.14,P=0.930)and in eyes with normal height of tear meniscus (X2=0.48,P=0.780).Mean surgery time in group II ((17.11±2.08)minutes)was significantly shorter than that in group l ((25.22±4.78)minutes)(t=13.84,P <0.01).Conclusion A quantitative locator can be used as an effective,safe,and less time-consuming instrument to facilitate conjunctival excision for symptomatic CCh treatment.
Effects of electroacupuncture versus nimodipine on long-term potentiation and synaptophysin expression in a rat model of vascular dementia

The present study stimulated Baihui (DU 20) and Dazhui (DU 14) acupoints in a rat model of vascular dementia with electroacupuncture to investigate changes in long-term potentiation and synaptophysin expression in the hippocampus. The results revealed that synaptophysin expression in brain tissues was increased after electroacupuncture. After high-frequency stimulation, the population spike latency was shortened and the excitatory postsynaptic potential slope and population spike amplitude were increased. In addition, cognitive function was enhanced, similar to the effects of intragastric perfusion of nimodipine. The results indicated that electroacupuncture at Baihui and Dazhui acupoints can improve learning and memory functions of a rat model of vascular dementia by promoting synaptophysin expression, enhancing hippocampal synaptic plasticity and accelerating synaptic transmission.
3.0T MR全心对比增强冠状动脉成像扫描的护理体会

随着MR软硬件系统的改善,磁共振冠状动脉成像(magnetic resonance coronary angiography, MRCA)已成为无创性检查冠状动脉疾病的最优手段 ~[1],而护理工作的优劣直接影响检查结果。本文报告MRCA的护理体会。
Water-soluble lipopolymer delivery of N-methyl-D-aspartic acid receptor 2B siRNA relieves chronic neuropathic pain in rats

Spinal dorsal horn N-Methyl-D-aspartic acid receptor 2B (NR2B) overexpression plays an important role in the production and maintenance of neuropathic pain. Because small interfering RNA (siRNA) can inhibit NR2B expression, siRNA may provide a novel approach to treat neuropathic pain and possibly nerve injury. However, an efficient and safe vector for NR2B siRNA has not been discovered. This study shows that a water soluble lipopolymer (WSLP) comprised of low molecular weight polyethyleneimine (PEI) and cholesterol can deliver siRNA targeting NR2B for the treatment of neuropathic pain. Results show that intrathecal injection of WSLP/siRNA complexes for 3 days inhibit NR2B gene expression with reductions in mRNA and protein levels by 59% and 54%, respectively, compared with control rats (P < 0.01). Injection of WSLP complexed with scrambled siRNA, or PEI with siRNA did not show this inhibitory effect. Moreover, injection of WSLP/siRNA complexes significantly relieved neuropathic pain at 3, 7, 12, and 21 days, while injection of WSLP with scrambled siRNA or PEI with siRNA did not. These results demonstrate that WSLP can efficiently deliver siRNA targeting NR2B in vivo and relieve neuropathic pain.
Scutellarin protects against Aβ-induced learning and memory deficits in rats: involvement of nicotinic acetylcholine receptors and cholinesterase

Aim: To examine the protective effects of scutellarin (Scu.) on rats with learning and memory deficit induced by β-amyloid peptide (Aβ). Methods: Fifty male Wistar rats were randomly divided into 5 groups: control, sham operation, Aβ, Aβ+Scu, and Aβ+piracetam groups. Aβ_(25-35) was injected into the lateral ventricle (10 μg each side). Scu (10 mg/2 mL) or piracetam (10 mg/2 mL was intragastrically administered per day for 20 consecutive days following Aβ treatment. Learning and memory was assessed with Morris water maze test. The protein and mRNA levels of nicotinic acetylcholine receptor (nAChR) α4, α7, and β2 subunits in the brain were examined using Western blotting and real-time PCR, respectively. The activities of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) in the brain and plasma were measured using Ellman's colorimetric method. Results: In Aβ group, the escape latency period and first platform cross was significantly increased, and the total number of platform crossings was significantly decreased, as compared with the control and the sham operation groups. Both Scu and piracetam treatment significantly reduced the escape latency period and time to cross platform, and increased the number of platform crosses, but there were no significant differences between Aβ+Scu and Aβ+piracetam groups. In Aβ group, the protein levels of nAChR α4 and α7 subunits in the cerebral.cortex were significantly decreased by 42%-47% and 58%-61%, respectively, as compared to the control and the sham operation groups. Scu treatment caused upregulation of α4 and α7 subunit proteins by around 24% and 30%, respectively, as compared to Aβ group, but there were no significant differences between Aβ+Scu and Aβ+piracetam groups. The protein level of nAChR β2 subunit had no significant difference among different groups. The mRNA levels of nAChR α4, α7, and β2 subunits were not significantly changed. In Aβ group, the activities of AChE and BuChE in the brain were significantly increased, but were significantly decreased in the plasma, as compared to the control and the sham operation groups. Scu or piracetam treatment restored the activities in brain and plasma nearly to the levels in the control group. Conclusion: The results suggest that Scu may rescue some of the deleterious effects of Aβ, possibly by stimulating nAChR protein translation and regulating cholinesterase activity.