mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Physics picture from neutron scattering study on Fe-based superconductors

Neutron scattering, with its ability to measure the crystal structure, the magnetic order, and the structural and magnetic excitations, plays an active role in investigating various families of Fe-based high-Tc superconductors. Three different types of antiferromagnetic orders have been discovered in the Fe plane, but two of them cannot be explained by the spin-densitywave (SDW) mechanism of nesting Fermi surfaces. Noticing the close relation between antiferromagnetic order and lattice distortion in orbital ordering from previous studies on manganites and other oxides, we have advocated orbital ordering as the underlying common mechanism for the structural and antiferromagnetic transitions in the 1111, 122, and 11 parent compounds. We observe the coexistence of antiferromagnetic order and superconductivity in the (Ba,K)Fe_2As_2 system, when its phase separation is generally accepted. Optimal T_c is proposed to be controlled by the local FeAs4 tetrahedron from our investigation on the 1111 materials. The Bloch phase coherence of the Fermi liquid is found crucial to the occurrence of bulk superconductivity in iron chalcogenides of both the 11 and the 245 families. Iron chalcogenides carry a larger staggered magnetic moment (> 2 μB/Fe) than that in iron pnictides (< 1μB/Fe) in the antiferromagnetic order. Normal state magnetic excitations in the 11 superconductor are of the itinerant nature while in the 245 superconductor the spin-waves of localized moments. The observation of superconducting resonance peak provides a crucial piece of information in current deliberation of the pairing symmetry in Fe-based superconductors.
Numerical study on the electron-wall interaction in a Hall thruster with segmented electrodes placed at the channel exit

Electron-wall interaction is always recognized as an important physical problem because of its remarkable influences on thruster discharge and performance. Based on existing theories, an electrode is predicted to weaken electron-wall interaction due to its low secondary electron emission characteristic. In this paper, the electron-wall interaction in an Aton-type Hall thruster with low-emissive electrodes placed near the exit of discharge channel is studied by a fully kinetic particle-in-cell method. The results show that the electron-wall interaction in the region of segmented electrode is indeed weakened, but it is significantly enhanced in the remaining region of discharge channel. It is mainly caused by electrode conductive property which makes equipotential lines convex toward channel exit and even parallel to wall surface in near-wall region; this convex equipotential configuration results in significant physical effects such as repelling electrons, which causes the electrons to move toward the channel center, and the electrons emitted from electrodes to be remarkably accelerated, thereby increasing electron temperature in the discharge channel, etc. Furthermore, the results also indicate that the discharge current in the segmented electrode case is larger than in the non-segmented electrode case, which is qualitatively in accordance with previous experimental results.
Reanalysis of the photoassociation spectrum of ~(133)Cs_2 (6P_(3/2)) 1_g state

Reanalysis of the photoassociation spectrum of the weakly binding (6S_(1/2)+6P_(3/2)) 1_g ~(133)Cs_2 levels, reported in the previous study [J. Mol. Spectro. 255 (2009) 106], is performed by using a Lu-Fano graph coupled to the improved LeRoy-Bernstein formula including two additional modified terms. A more accurate coefficient (c_3) is obtained for the leading long-range potential (-c_3/R~3) of a diatomic molecule.
Resonance suppression and electromagnetic shielding effectiveness improvement of an apertured rectangular cavity by using wall losses

The cavity-mode resonance effect could result in significant degradation of the shielding effectiveness (SE) of a shielding enclosure around its resonance frequencies. In this paper, the influence of coated wall loss on the suppression of the resonance effect is investigated. For this purpose, an equivalent circuit model is employed to analyze the SE of an apertured rectangular cavity coated with an inside layer of resistive material. The model is developed by extending Robinson's equivalent circuit model through incorporating the effect of the wall loss into both the propagation constant and the characteristic impedance of the waveguide. Calculation results show that the wall loss could lead to great improvement on the SE for frequencies near the resonance but almost no effect on the SE for frequencies far away from the resonance.
Directed transport of coupled Brownian ratchets with time-delayed feedback

A time-delayed feedback ratchet consisting of two Brownian particles interacting through the elastic spring is considered. The model describes the directed transport of coupled Brownian particles in an asymmetric two-well ratchet potential which can be calculated theoretically and implemented experimentally. We explore how the centre-of-mass velocity is affected by the time delay, natural length of the spring, amplitude strength, angular frequency, external force, and the structure of the potential. It is found that the enhancement of the current can be obtained by varying the coupling strength of the delayed feedback system. When the thermal fluctuation and the harmonic potential match appropriately, directed current evolves periodically with the natural length of the spring and can achieve a higher transport coherence. Moreover, the external force and the amplitude strength can enhance the directed transport of coupled Brownian particles under certain conditions. It is expected that the polymer of large biological molecules may demonstrate a variety of novel cooperative effects in real propelling devices.
地球科学的两次革命

第二次世界大战之后两次伟大的革命震动了地球科学:一个涉及固体地球,即大陆漂移;一个关于冰期之争,即更新世是否只有4次冰期。前者经过大约100年的长期准备,但是人们立即接受了这个概念。后者则来得相对突然,经过几十年才得到承认。
非二氧化碳温室气体控制的战略与技术选择

1997年签署的《京都议定书》中,明确界定了除二氧化碳(C0_2)外的其他5种温室气体,即甲烷(CH_4) 、氧化亚氮(CO_2) 、氢氟碳化合物(HFCs) 、全氟化碳(PFCs) 、六氟化硫(SF_6). 2011年德班谈判时,关于《京都议定书》第二承诺期的内容中,又增加了三氟化氮(NF_3) 。至此,在《联合国气候变化框架公约》(UNFCCC)下总共有6种非C0_2温室气体,可分为三大类:CH_4、N_20、含氟气体。其中, CH_4和N_20是自然界中本来就存在的成分,由于人类活动而增加,而含氟气体则完全是人类活动的产物。为了便于衡量这些非C0_2温室气体的全球变暖效应,政府间气候变化专门委员会(IPCC)第三次评估报告中引入了C0_2当量这一概念。一种气体的C0_2当量是通过把该气体的吨数乘以其全球增暖潜势(GWP)后得出,通过这种方法可把不同温室气体的增温效应标准化。
BNU-ESM模式及其开展的CMIP5试验介绍

地球系统模式是采用数值模拟方法研究地球各个圈层之间联系及其演变规律,理解过去气候演变过程并预测未来潜在全球气候变化的重要工具。相对于气候系统模式,地球系统模式包含更多的生物地球化学过程,未来还将考虑日地空间环境和固体地球等概念。第五次耦合模式比较计划(CMIP5)是世界气候研究计划(the World Climate Research Programme, WCRP)耦合模式工作组(Working Group on Coulped Model, WGCM)于2008年9月启动的,旨在评估各耦合模式或地球系统模式在当前了解较少的碳循环和云反馈过程中的差异机制,检验气候的可预报性并探索年代尺度气候系统预报能力,并确定为何同样的气候强迫输入条件各模式结果会有一系列表现差异,同时期待能够解决IPCC第四次评估报告(AR4)引出的几个科学问题,并为第五次评估报告(AR5)提供有价值的模式评估数据集吒CMIP5计划通过采用分布式存储构架的地球系统网格联盟(Earth System Grid Federation, ESGF)站点存储并发布模式数据。
Dearomatization of normal paraffin by adsorption process using synthesized NaX zeolite

Linear alkyl benzenes (LABs) are the main materials for detergent production. The presence of aromatic compounds in this material can decrease the quality of the final product and enhance the deactivation rate of catalysts. In this research we used zeolite NaX for de-aromatization of the recycled paraffin from the alkylation unit of an LAB production complex. The effect of different parameters on the removal efficiency of adsorbent was studied and optimized. To study the re-usability of the adsorbent, the breakthrough curves were obtained by using a fixed bed column filled with the adsorbent. The results indicated that the adsorbent capacity remained unchanged after three regeneration cycles. The Langmuir and Freundlich adsorption models were applied to describe the equilibrium isotherms. It was concluded that the Langmuir model agreed well with the experimental data. The calculated thermodynamic parameters of the adsorption showed that the adsorption process was spontaneous and exothermic. The reaction rate was estimated by the pseudo-second order kinetic model.
Multiple fault diagnosis of down-hole conditions of sucker-rod pumping wells based on Freeman chain code and DCA

It is important to achieve continuous, stable and efficient pumping well operation in actual oilfield operation. Down-hole pumping well working conditions can be monitored in real-time and a reasonable production scheme can be designed when computer diagnosis is used. However, it is difficult to make a comprehensive analysis to supply efficient technical guidance for operation of the pumping well with multiple faults of down-hole conditions, which cannot be effectively dealt with by the common methods. To solve this problem, a method based on designated component analysis (DCA) is used in this paper. Freeman chain code is used to represent the down-hole dynamometer card whose important characteristics are extracted to construct a designated mode set. A control chart is used as a basis for fault detection. The upper and lower control lines on the control chart are determined from standard samples in normal working conditions. In an incompletely orthogonal mode, the designated mode set could be divided into some subsets in which the modes are completely orthogonal. The observed data is projected into each designated mode to realize fault detection according to the upper and lower control lines. The examples show that the proposed method can effectively diagnose multiple faults of down-hole conditions.
Characteristics of the turbidite fan in the Wenchang Formation of the Enping Sag, Pearl River Mouth Basin, China and its hydrocarbon significance

A turbidite fan in the Eocene upper Wenchang Formation in the Enping Sag, Pearl River Mouth Basin (PRMB) has been studied using seismic, logging and borehole data. The fan is characterized by parallel progradation on the dip seismic profile and is mound-shaped or lenticular-shaped on the strike seismic profile. The study of the core and logging data from well EP17-3-1, which is located in the front side of the turbidite fan, shows that this fan is a set of normal grading sand beds, interbedded within thick dark grey mudstones of semi-deep to deep lake deposits in the Wenchang Formation. The fan is interpreted as a sand/mud-rich turbidite fan that has an area of over 140 km~2 and a maximum thickness of over 340 m. Combined with a study of the regional geological background and previous provenance analysis of the Eocene Wenchang Formation, the main potential provenances for the turbidite fan are considered to be the Panyu low-uplift and northern fault terrace zone. The Enping Sag is considered to be a half graben-like basin whose north side is faulted and whose south side is overlapped. Basement subsidence in the Eocene was mainly controlled by boundary faults which dip relatively steeply on the north side, causing the subsidence center of the Enping Sag in this stage to be close to the north boundary faults. Sustained faults developed in the Enping Sag during the Eocene caused an increase of the relative height difference between the north and the south uplift zone in the Enping Sag. Affected by the second episode of the Zhuqiong movement (39-36 Ma) in late Eocene, sediments which had accumulated on the Panyu low-uplift zone were triggered and moved toward the subsidence center of the Enping Sag and formed the turbidite fan. The second episode of the Zhuqiong movement is the most important triggering factor for the formation of the turbidite fan in the Wenchang Formation. Seismic attribute characterization shows that the low frequency energy is enhanced and high frequency energy is weakened when seismic waves propagate through the oil-bearing zone in this fan. Amplitude versus offset (AVO) anomalies are observed in the seismic data and abnormally high pressure is encountered. The turbidite fan in the Wenchang Formation has provided important information for sedimentary evolution in deep layers of the Enping Sag and pointed to a new direction for the hydrocarbon exploration in the study area.
Controlling effects of the Ordovician carbonate pore structure on hydrocarbon reservoirs in the Tarim Basin, China

The Ordovician carbonate reservoirs in the Tarim Basin with secondary dissolution pores and vugs have complicated pore structures. The weathering crust reservoirs mainly consist of large cavities or vugs connected by fractures, but most of the reef-shoal reservoirs have complex and small throats among matrix pores. The pore structure can be divided into four types: big pore and big throat, big pore but small throat, small pore and small throat, and fracture type. Most of the average throat radius falls between 0.03 and 0.07 μm, close to that of unconventional reservoirs except in local areas with developed fractures. Fluid driving force analysis shows that the differentiation of fluid is mainly controlled by the throat radius in two kinds of mechanism separated by the critical throat radius about 0.1 μm. There is obvious fluid differentiation and oil/gas/water contact in fracture-cavity reservoirs with big throats. However, most of reservoirs under the critical throat radius have high capillary pressure, which resulted in incomplete differentiation of gas/oil/water, and complicated fluid distribution and fluid properties in the unconventional reservoirs.
护理干预在商环内置免拆环法成人包皮环切术中的应用

近年来,采用商环内置免拆环法与传统手术相比有明显优势:微创、简便、术中无出血、无缝合、术后瘢痕轻、外形美观等。我院2009年3月至2012年3月采用护理干预措施护理商环内置免拆环法行成人包皮环切术699例,取得了良好效果。
丹参川芎嗪注射液治疗放射性肺炎的疗效及护理

目的观察丹参川芎嗪注射液治疗放射性肺炎的疗效并探讨其护理措施. 方法72例放射性肺炎患者随机分为对照组和观察组,两组均给予地塞米松和头孢唑啉钠抗炎治疗,仅观察组在此基础上加用丹参川芎嗪注射液治疗;分析两组的治疗效果,治疗前、治疗1周和1个月后的Karnofsky生活质量评分(KPS评分)及胸部影像表现情况. 结果观察组的治疗总有效率高于对照组(P<0.05),痊愈例数多于对照组(P<0.05);两组治疗后的KPS评分及胸部影像表现情况均优于治疗前;观察组治疗后的KPS评分均高于对照组(P<0.05);除治疗1个月后的片状阴影外,胸部影像表现情况均优于对照组. 结论丹参川芎嗪注射液治疗放射性肺炎的疗效较好,可提高其治疗有效率及生活质量评分,而相应的护理措施也具有一定的促进作用.
Effect of pH Value on Stress Corrosion Cracking of X70 Pipeline Steel in Acidic Soil Environment

The effect of pH value on the stress corrosion cracking (SCC) of API X70 pipeline steel in simulated acidic soil solutions was investigated by using slow strain rate test, electrochemical polarization curves, electrochemical impedance spectroscopy, and scanning electron microscopy. pH plays an important role in the susceptibility and electrochemical mechanism of SCC. The pH higher than 5 has no significant effect on electrochemical processes. By contrast, the pH lower than 5 intensifies cathodic hydrogen evolution reactions, thus increasing the cathodic current and corrosion potential. Under different pH values, the SCC mechanism of X70 pipeline steel varies among anodic dissolution (AD), hydrogen embrittlement (HE), and the combination of AD and HE (AD + HE) with variations of applied potential. At -850 mVSCE, the SCC mechanism is HE if pH is less than 4 or AD + HE if pH value is more positive.
Effect of Ni Addition on Microstructure of Matrix in Casting Tungsten Carbide Particle Reinforced Composite

Microstructure of the matrix directly influences the performance and the application of metal matrix composites. By using vacuum casting-infiltration method to manufacture casting tungsten carbide particle reinforced composite, the addition of Ni can alter the microstructure of the matrix of composite. High carbon chromium steel was chosen as the substrate. The casting process was achieved at 1580 °C with vacuum degree of 0.072–0.078 MPa. Padding of the molten steel in each part of the preform was different, and the solidification of each part of the composite was different, too. Microstructure of the matrix was various in different parts of the composite. The Ni addition had enlarged the austenite zone in matrix, which would improve the corrosion resistance of the composite. The phase identification of the composite was performed by X-ray diffraction technique. The result showed that Fe_3W_3C was the primary precipitated carbide and its composition had a direct link with the decomposition of the casting tungsten carbide particles. The hardness of the matrix mainly depended on the reinforced carbide, i.e. Fe_3W_3C.
保定市县、市两级综合医院住院患者抑郁症识别率和治疗率现况调查

目的了解保定市县、市两级综合医院住院患者中抑郁症的检出率、医生的识别率和治疗率现况,为相关部门开展精神卫生工作提供依据。方法采用随机分层整群抽样方法抽取保定市县、市两级综合医院住院患者共1074例进行抑郁症状量表筛查,对筛查阳性者用简明国际神经精神访谈中文版(Mini International Neuropsychiatric Interview,MINI)诊断,查阅诊断为抑郁症患者的病历资料,并对81名主管医生进行问卷调查。结果MINI共诊断抑郁症患者116例,市级和县级综合医院住院患者中抑郁症校正检出率分别为12.9%和8.6%。综合医院病历资料中医生对抑郁症的识别和治疗率分别是13.0%和7.8%。其中地市级医院医生对抑郁症的识别和治疗率分别是14.8%和8.6%;县级医院医生对抑郁症的识别和治疗率分别是8.6%和5.7%。不同级别医院医生对抑郁症治疗的态度中"应转诊/会诊治疗"间差异有统计学意义(P=0.032)。结论保定市综合医院抑郁症的检出率偏高,医生对抑郁症的识别和治疗率低,不同级别医院医生对抑郁症治疗态度有所不同。
Abnormal electric transport property and magnetoresistance stability of La–Sr–K–Mn–O system

The perovskite samples La_(1?x) (Sr_(1?y) K _y) _x MnO_3 (y = 0.0, 0.2, 04, 0.6, 0.8) were prepared by the solid-state reaction method with comparatively low sintering temperature and with comparatively short sintering time, and the electric transport property and temperature stability of MR of this system were studied. The ρ–T curves show the abnormal phenomenon that with the increase of K doping amount, resistivity increases, and the insulator–metal transition temperature decreases, which is because the influence of the occupation disorder degree of A-site ions σ _2 on the electric transport property of perovskite manganites is larger than that of the radius of A-site ions 〈r A〉. In the temperature range below 225 K, MR increases continuously with the decrease of temperature, which is the characteristic of low-field magnetoresistance; in the comparatively wide temperature range near 250 K, the MR–T curves of all the samples are comparatively flat, and the value of MR almost does not change with temperature, which shows the temperature stability of magnetoresistance, and can be explained by the competition between the low-field magnetoresistance induced by spin-dependent tunneling of surface phase and the intrinsic magnetoresistance of grain phase. The magnetoresistance value of the sample with y = 0.8 keeps at (7.92 ± 0.36) % in the very wide temperature range of 225–275 K, and this is a good reference for the preparation of this kind of sample with practical application value in the future.
应重视城市绿地的生态功能研究

城市是-类似人类活动中心的社会、经济和自然复合生态系统。城市绿地是城市复合生态系统的重要组成部分,其系统结构和功能在改善环境质量、美化景观、维护城市生态平衡、促进城市可持续发展等方面起着十分重要的作用。然而,城市的快速扩展和人类活动的不断加剧,明显地影响了城市绿地生态系统,导致城市自然生态系统的服务功能不断降低。随着城市化进程的加速和城市环境问题的加剧,人们越来越认识到绿色空间生态服务功能的重要性,在城市绿化建设中不仅关心绿地美化、观赏、休憩等功能,更加注重绿地的生物多样性级生态系统服务综合功能,城市绿地已成为衡量城市地区生态可持续的重要标准。
GLOBAL EXISTENCE OF SOLUTIONS OF CAUCHY PROBLEM FOR GENERALIZED BBM-BURGERS EQUATION

In this paper, the existence and the uniqueness of the local generalized solution and the local classical solution of the Cauchy problem for the generalized BBM-Burgers equation are proved. The existence and the uniqueness of the global generalized solution and the global classical solution for the Cauchy problem of equation (1) are proved when n=3,2,1. Moreover, the decay property of the solution is discussed.
GRADIENT ESTIMATES AND ENTROPY FORMULAE FOR WEIGHTED p-HEAT EQUATIONS ON SMOOTH METRIC MEASURE SPACES

Let (M,g,e~(-f)dv) be a smooth metric measure space. In this paper, we consider two nonlinear weighted p-heat equations. Firstly, we derive a Li-Yau type gradient estimates for the positive solutions to the following nonlinear weighted p-heat equation on M×[0,∞), where 1
EXISTENCE UNIQUENESS AND DECAY OF SOLUTION FOR FRACTIONAL BOUSSINESQ APPROXIMATION

The Boussinesq approximation finds more and more frequent use in geological practice. In this paper, the asymptotic behavior of solution for fractional Boussinesq approximation is studied. After obtaining some a priori estimates with the aid of commutator estimate, we apply the Galerkin method to prove the existence of weak solution in the case of periodic domain. Meanwhile, the uniqueness is also obtained. Because the results obtained are independent of domain, the existence and uniqueness of the weak solution for Cauchy problem is also true. Finally, we use the Fourier splitting method to prove the decay of weak solution in three cases respectively.
综合性大学本科生焦虑、抑郁与躯体化症状及其影响因素研究

目的探索高校大学生焦虑、抑郁及躯体化症状的现况并分析其影响因素。方法采取分层抽样方法在四川某综合性高校抽取1 380例大学生,选用患者健康问卷(PHQ-15)、焦虑自评量表(SAS)及抑郁自评量表(SDS)对其进行心理调查。结果1 380例大学生中躯体化症状严重程度处于中度及中度以上的占11.8%;自感严重焦虑症状者占7.8%;自感严重抑郁症状者占23.3%;性别、年龄、学院及年级等因素对躯体化症状影响较大而对焦虑与抑郁的影响较小,是否为独生子女或家庭收入对3种症状影响均不明显;PHQ-15结果与SAS的相关系数r为0.465(P<0.05),与SDS的相关系数r为0.375(P<0.05),SAS与SDS之间相关系数r为0.783(P<0.05)。结论大学生抑郁症状与躯体化症状较为严重;大学生躯体化症状与焦虑及抑郁症状三者间均有一定相关性;不同因素对大学生心理健康的影响有差异。
胎母输血综合征2例报道

FMH是近年来逐渐被认识和关注的一种产科并发症,其发病率约为1/1 000~1/3 000,80%以上的病例原因不明。常见的高危因素包括胎盘因素、母体因素(高血压、自身免疫性疾病)以及医源性的羊膜腔穿刺、脐带穿刺等。临床主要表现为胎动减少、甚至消失,心律失常等;典型病例胎心监护可出现正弦波图形,但也有些病例出现晚期减速波,甚至无任何特异性表现。新生儿外观表现为贫血貌、皮肤黏膜苍白、循环衰竭等,苍白与窒息程度不一致,积极复苏后无明显改善。FMH对围产儿预后的影响主要取决于失血量及其速度。国外文献报道FMH新生儿容易并发神经损伤及脑损伤甚至围产儿死亡。因FMH临床表现不典型,故产前诊断较困难,本组2例病例均是产后诊断。过去诊断FMH主要根据孕妇胎动异常以及胎监出现正弦波,目前FMH的诊断主要建立在胎儿贫血与母体循环中HbF比例上升的基础上。常用的实验室检查有酸洗脱试验(Kleihaue-Bet Test,KB试验)、AFP 、流式细胞术(FMC)等。有学者认为胎儿大脑中动脉峰值流速测定是预测胎儿贫血首选的无创性检查。FMH的治疗取决于孕周的大小和病情严重程度,越早治疗效果越好。孕周小、胎儿不成熟的尽可能的延长孕周,主要是宫内输血治疗;若胎儿已成熟(孕周>35周),则应尽快剖宫产终止妊娠。新生儿的治疗则根据贫血程度积极进行输血补液等处理,降低围产儿死亡率,改善预后。但如何能在早期发现FMH,这将对改善预后起着至关重要的作用。本次报道的2例病例均是足月妊娠,治疗上都是急诊剖宫产终止妊娠,但是2例围产儿结局都不良,分析原因可能与我们对本病的认识不足,同时检查手段有限以及患者就诊不及时有关。在今后的临床工作中应进一步强调患者自我监测胎动的重要性,胎儿监护异常应结合高危因素综合分析,提高警惕,积极处理改善围产儿的结局。
Rare double fracture-dislocation of the thumb: a case report and review of the literature

Simultaneous fracture/dislocation of the thumb carpometacarpal (CMC)joint and dislocation of the metacarpophalangeal (MCP) joint is considered as a rare injury pattern. We report an unusual case of dorsal dislocation of MCP joint of the thumb associated with extraarticular fracture of the base of the first metacarpal in a 28-year-old man. The dislocation of MCP joint had been missed during initial presentation at a peripheral centre. The patient made an uneventful recovery following open reduction and fixation with 1.25 mm Kirschner wire of the MCP joint along with repair of the ulnar collateral ligament. This injury pattern has not been previously reported to the best of our knowledge in the English-language based medical literature.
Morphological study of Schwann cells remyelination in contused spinal cord of rats

Objective: To study the role and effect of Schwann cells (SCs) remyelination in contused spinal cord. Methods: Green fluorescence protein expressing-SCs were transplanted into the epicenter, rostral and caudal tissues of the injury site at 1 week after the spinal cords were contused. At 6 weeks, the spinal cords were removed for cryosections, semithin sections and ultrathin sections, and then immunocytochemical staining of myelin basic protein (MBP), PO protein (PO) and SI00 protein (SI00) was carried out on the cryosections. Qualitative and semiquantitative analyses were performed on the cryosections and semithin sections. Ultrastructure of myelinated fibers was observed on the ultrathin sections under electron microscope. Results: Transplanted SCs and myelinated fibers im-munocytochemically labeled by MBP, PO as well as S100 distributed in whole injured area. The quantity of myelinated fibers labeled by the three myelin proteins showed no statistical difference, however, which was significantly larger than that of controls. On the semithin sections, the experimental group demonstrated more myelinated fibers in the injured area than the controls, but the fibers had smaller diameter and thinner myelin sheath under electron microscope. Conclusion: SCs can promote regeneration of injured nerve fibers and enhance remyelination, which may be histological basis of SCs-mediated functional repair of injured spinal cords.
肝病病理的共同特征:Hedgehog信号通路活化

Hedgehog.(Hh)信号通路最初是在果蝇中发现的,该通路非常保守,在胚胎发育过程中,其决定着许多关键细胞的命运如增值、分化、凋亡、迁移等,从而广泛调节胚胎形成、发育以及众多组织的重塑[1气在成年时的许多组织,包括肝脏的损伤修复中发挥着重要作用。该信号通路主要包括Hh生成细膨和Hh反库细胞,前者能产生一个配体家族包括Sonic hedgehog (Shh),Indian hedgehog (Ihh),Desert hedgehog.(Dhh) ;然后通过自分泌、。旁分泌和内分泌途径作用于后者,并与其细胞膜上的受体Patched (Ptc)结合,同时通过抑制Smoothened (Smo)分子活性启动胞内信号通路,导致Glioblastoma (Gli)家族转录因子(Glil,G1i2,Gli3) 、前往细胞核内,调节Gli靶基因的表达.Hh信号通路激活通常会增強Hh反应细胞的生长和活力,而阻断其通路通常会导致这些细胞的凋亡,除非其他一些局部的分化因子会加速这些细胞分化为更成熟的—胞以至于这些细胞不再需要Hh信号。因此,Hh信号通路的上调和下调能为那些对Hh配体有反应的细胞提供选择性生长优势,而周围缺乏Hh受体的其他细胞则不行。其结果是引起Hh反应细胞要么增大,要么收缩,这样调节许多组织中细胞的重塑。