mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Effect of emitter layer doping concentration on the performance of a silicon thin film heterojunction solar cell

A novel type of n/i/i/p heterojunction solar cell with a-Si:H(15nm)/a-Si:H(10nm)/ epitaxial c-Si(47μm)/epitaxial c-Si(3μm) structure is fabricated by using the layer transfer technique, and the emitter layer is deposited by hot wire chemical vapour deposition. The effect of the doping concentration of the emitter layer S_d (S_d =PH_3 /(PH_3 +SiH_4 +H_2 )) on the performance of the solar cell is studied by means of current density-voltage and external quantum efficiency. The results show that the conversion efficiency of the solar cell first increases to a maximum value and then decreases with S_d increasing from 0.1% to 0.4%. The best performance of the solar cell is obtained at S_d = 0.2% with an open circuit voltage of 534 mV, a short circuit current density of 23.35mA/cm~2, a fill factor of 63.3%, and a conversion efficiency of 7.9%
Thermodynamic and kinetic study on interfacial reaction and diamond graphitization of Cu Fe-based diamond composite

Cu-Fe based diamond composites used for saw-blade segments are directly fabricated by vacuum and pressure- assisted sintering. The carbide forming elements Cr and Ti are added to improve interfacial bonding between diamond and the Cu-Fe matrix. The interfacial reactions between diamond/graphite and Cr or Ti, and diamond graphitization are investigated by thermodynamics/kinetics analyses and experimental methods. The results show that interfacial reactions and graphitization of diamond can automatically proceed thermodynamically. The Cr_3C_2, Cr_7C_3, Cr_(23)C_6, and TiC are formed at the interfaces of composites by reactions between diamond and Cr or Ti; diamond graphitization does not occur because of the kinetic difficulty at 1093 K under the pressure of 13 MPa
Instantaneous and time-averaged flow structures around a blunt double-cone with or without supersonic film cooling visualized via nano-tracer planar laser scattering

In a Mach 3.8 wind tunnel, both instantaneous and time-averaged flow structures of different scales around a blunt double-cone with or without supersonic film cooling were visualized via nano-tracer planar laser scattering (NPLS), which has a high spatiotemporal resolution. Three experimental cases with different injection mass flux rates were carried out. Many typical flow structures were clearly shown, such as shock waves, expansion fans, shear layers, mixing layers, and turbulent boundary layers. The analysis of two NPLS images with an interval of 5 μs revealed the temporal evolution characteristics of flow structures. With matched pressures, the laminar length of the mixing layer was longer than that in the case with a larger mass flux rate, but the full covered region was shorter. Structures like K-H (Kelvin-Helmholtz) vortices were clearly seen in both flows. Without injection, the flow was similar to the supersonic flow over a backward-facing step, and the structures were relatively simpler, and there was a longer laminar region. Large scale structures such as hairpin vortices were visualized. In addition, the results were compared in part with the schlieren images captured by others under similar conditions
Screw dislocations interacting with two asymmetrical interfacial cracks emanating from an elliptical hole

The interaction between screw dislocations and two asymmetrical interfacial cracks emanating from an elliptic hole under loads at infinity is studied. The closed-form solution is derived for complex potentials. The stress intensity factor and the critical applied stress for the dislocation emission are also calculated. In the limiting cases, well-known results can be obtained from the present solutions. Moreover, new exact solutions for a screw dislocation interacting with some complicated cracks are derived. The results show that the shielding effect increases with the increase in the length of the other cracks and the minor semi axis, but decreases with the increase of dislocation azimuth. The repulsion acting on the dislocation from the other phase and the other crack extend in the horizontal direction, which makes the dislocation emission at the crack tip take place more easily, but the minor semi axis of the elliptical hole extending in the vertical direction makes it more difficult
Design and realization of a magnetic-type absorber with a broadened operating frequency band

In this paper, we present an efficient method to obtain absorbers with broadened operating frequency bands. They are accomplished by using conventional magnetic absorbing materials (MAMs) in the forms of array and mesh structures, which are similar to those in the case of a frequency selective surface. The proposed approach is verified not only by simulations but also by experimental results under the normal incidence at microwave frequencies. Moreover, the wideband absorber is lighter than the conventional magnetic absorber. These results indicate that our proposed absorbing structures can be used for designing good electromagnetic absorbers
Creation of quantum correlations via the initial classical-mixed states

Using the pseudomode method, we theoretically analyze the creation of quantum correlations between two two-level dipole-dipole interacting atoms coupled with a common structured reservoir with different coupling strengths. Considering certain classes of initial separable-mixed states, we demonstrate that the sudden birth of atomic entanglement as well as the generation of stationary quantum correlations occur. Our results also suggest a possible way to control the occurrence time of entanglement sudden birth and the stationary value of quantum correlations by modifying the initial conditions of states, the dipole-dipole interaction, and the relative coupling strength. These results are helpful for the experimental engineering of entanglement and quantum correlations
Are human dental papilla-derived stem cell and human brain-derived neural stem cell transplantations suitable for treatment of Parkinson's disease?

Transplantation of neural stem cells has been reported as a possible approach for replacing impaired dopaminergic neurons. In this study, we tested the efficacy of early-stage human dental papilla-derived stem cells and human brain-derived neural stem cells in rat models of 6-hydroxydopamine-induced Parkinson’s disease. Rats received a unilateral injection of 6-hydroxydopamine into right medial forebrain bundle, followed 3 weeks later by injections of PBS, early-stage human dental papilla-derived stem cells, or human brain-derived neural stem cells into the ipsilateral striatum. All of the rats in the human dental papilla-derived stem cell group died from tumor formation at around 2 weeks following cell transplantation. Postmortem examinations revealed homogeneous malignant tumors in the striatum of the human dental papilla-derived stem cell group. Stepping tests revealed that human brain-derived neural stem cell transplantation did not improve motor dysfunction. In apomorphine-induced rotation tests, neither the human brain-derived neural stem cell group nor the control groups (PBS injection) demonstrated significant changes. Glucose metabolism in the lesioned side of striatum was reduced by human brain-derived neural stem cell transplantation. [~(18) F]-FP-CIT PET scans in the striatum did not demonstrate a significant increase in the human brain-derived neural stem cell group. Tyrosine hydroxylase (dopaminergic neuronal marker) staining and G protein-activated inward rectifier potassium channel 2 (A9 dopaminergic neuronal marker) were positive in the lesioned side of striatum in the human brain-derived neural stem cell group. The use of early-stage human dental papilla-derived stem cells confirmed its tendency to form tumors. Human brain-derived neural stem cells could be partially differentiated into dopaminergic neurons, but they did not secrete dopamine.
Filtration, automorphisms, and classification of infinite-dimensional odd contact superalgebras

The principal filtration of the infinite-dimensional odd contact Lie superalgebra over a field of characteristic p > 2 is proved to be invariant under the automorphism group by investigating ad-nilpotent elements and determining certain invariants such as subalgebras generated by some ad-nilpotent elements. Then, it is proved that two automorphisms coincide if and only if they coincide on the ?1 component with respect to the principal grading. Finally, all the odd contact superalgebras are classified up to isomorphisms.
Ⅲ型前列腺炎的疼痛机制研究

Ⅲ型前列腺炎(chronic pelvic pain syndrome,CPPS)是男性生殖泌尿系统常见疾病之一,占慢性前列腺炎的90%以上。由于前列腺固有的解剖结构及生理特点,造成了Ⅲ型前列腺炎的临床表现五花八门,且治愈困难。虽然Ⅲ型前列腺炎并不是威胁生命的恶疾,但其严重影响该病患者的生活质量,是临床工作中的棘手问题。疼痛是Ⅲ型前列腺炎的主要临床症状,同时也是降低患者生活质量的主要因素之一。近年来,尽管对Ⅲ型前列腺炎疼痛发生的基础及临床研究较多,但是由于其发生发展的机制复杂,存在争议,目前的研究还远未阐明。本文就Ⅲ型前列腺炎疼痛发生机制的研究进展作一综述。
特种工程塑料聚醚醚酮应用进展

聚醚醚酮(PEEK)是由帝国化学(ICI)公司在1977年首先开发成功,1982年正式以VICTREX~? PEEK销售,1993年 VICTREX(威格斯)收购ICI生产工厂成为独立公司。威格斯拥有市场上最广泛的聚芳醚酮类产品,目前每年产能4250t, 此外,VICTREX~?聚芳醚酮第3个工厂年产2900t也将于2015年年初投产,届时产能将超过7000t/a。
食用油罐区的建筑防火设计

食用油罐区规模越来越大,油罐区防火设计的要求也越来越高.结合油脂行业特点和规范要求,对油罐区平面布置原则、隔油堤设置、油品输送设施及消防设施等的设计要求进行探讨,以满足已有和新建设施的安全防护要求,并对食用油罐区总储量进行展望.
腹腔镜下子宫三角形切除术中3种方法阻断子宫动脉的比较研究

目的:探讨腹腔镜下子宫三角形切除术中采用丝线或钛夹结扎、双极碳化、红尿管捆扎3种方法阻断子宫动脉的临床应用效果。方法:对997例患者行腹腔镜下子宫三角形切除术，术中采用3种不同方式阻断子宫动脉，比较3组患者术中、术后情况。结果:3组患者术后疼痛发生率及术后使用抗生素、体温升高、肛门排气、术后下床活动和术后住院时间比较，差异均无统计学意义(P>0.05)。手术时间、术中出血量红尿管捆扎组较丝线或钛夹结扎组、双极碳化组高(分别为80.2±29.0分钟、79.3±31.0分钟、71.2±28.0分钟，212.0±38.0 ml、121.0±52.0ml、109.0±21.0 ml)，差异有统计学意义(P<0.05，P<0.01);丝线或钛夹结扎组、双极碳化组术后性生活恢复时间均较红尿管捆扎组长(33.0±3.6天、51.0±4.6天VS 21.0±4.7天)，差异有统计学意义(P<0.05)。3组均无手术并发症发生。结论:丝线或钛夹结扎、双极碳化法操作容易，手术时间短，术中出血少;红尿管捆扎法能较好保护患者术后血供，术后性生活恢复时间较短。应根据医院手术器械和手术医生技术及患者的具体情况选择子宫动脉阻断方式。
MRI在胎儿医学中的应用

MRI是一种生物磁自旋成像技术，常规信号主要来源于人体水分子中的质子，部分组织信号来源于脂肪组织中的质子;因此，MRI具有无电离辐射的特点。此外，MRI还具有软组织分辨率高及多方位成像等独特优势，图像质量不受胎位、母体体型、羊水量、肠道气体及骨骼等因素的影响。自1983年Smith等首次报道以来，胎儿MRI检查已经从实验性产前成像方法发展为重要的临床影像检查手段，成为产科超声检查的重要补充手段。随着软硬件不断升级，快速MRI技术能够在1秒之内无需镇静或屏气的条件下获得高质量胎儿图像。能用于评价胎儿的正常解剖、胎动、胎儿运动发育及发育变异，诊断胎儿先天性疾病以及胎儿死亡后的替代尸检，还可了解胎儿器官的功能与代谢活动，尤其在中枢神经系统、胸腹部疾病的产前诊断具有重要的价值。因而胎儿MRI已经受到产科临床的广泛重视。
新辅助化疗的不良反应及预防处理

由于绝大多数抗肿瘤药物缺乏抗肿瘤特异性,即在杀死肿瘤细胞的同时,对正常组织细胞也有不同程度的损伤作用,引起心、肝、肾、肺、胃肠道及骨髓等重要脏器受损。因此,化疗中应关注不良反应,积极预防不良反应,避免严重不良反应的发生。
急性小脑炎性共济失调康复的1例报告

急性小脑性共济失调是由多种原因引起的以急性小脑功能异常为主要特征的综合征.病变多以局限性小脑炎为主,临床上常以步行障碍、言语障碍、眼球震颤及意向性震颤为表现特点.表现出典型的小脑步态,即步基增宽,步行时双下肢跨前过多,躯干滞后而向后倾倒,或躯干向病变侧倾倒,由于肌张力失调及辩距不良,步行时出现躯干及下肢的粗大震颤.小脑炎性共济失调如确诊,临床上采取综合联合用药,预后较好,只有少数患者留下不同程度的功能障碍,目前关于小脑炎性共济失调的康复报道较少,现将我科收治的1例典型的小脑炎共济失调的患者康复情况报道如下:
构皮滩水电站下游RCC围堰仓面质量控制

构皮滩水电站位于贵州省余庆县构皮滩口上游1.5 km的乌江上,上游距乌江渡水电站137 km,下游距河口涪陵455 km,为乌江开发的第六个梯级水电站。
呼和浩特抽水蓄能电站下水库拦河坝固结灌浆试验分析

呼和浩特抽水蓄能电站下水库位于哈拉沁沟与大西沟交汇处上游,主要建筑物由拦河坝、拦沙坝及左岸泄洪排沙洞组成。拦沙坝和拦河坝均采用碾压混凝土重力坝,拦河坝设计最大坝高73.0 m。坝基岩性为斜长角闪岩和黑云母角闪斜长片麻岩以及第四系松散堆积物,地质构造表现为断层破碎带、裂隙密集带,发育有高陡倾角多微张裂隙。坝基面以微风化未卸荷岩体为主,岩体的透水性受裂隙发育程度控制, 并随着埋深增大有所降低,局部小断层发育地带形成强透水凹槽。固结灌浆的施工受混凝土施工影响,分坝段、分高程、分阶段进行,工期要求紧、施工强度高,为了验证固结灌浆设计参数及施工工艺进行生产性试验。
南水北调中线工程七里河倒虹吸导流设计及施工

七里河渠道倒虹吸建筑物总长865 m,其中进口段长75 m,管身段长700 m,出口段长90 m.进口设检修闸,出口设节制闸,组成了以倒虹吸为主体的枢纽工程.管身为3孔一联钢筋混凝土结构,单孔过水断面尺寸(高×宽)为6.5 m×6.5 m. 进口检修闸为开敞式钢筋混凝土整体结构,闸室长15m,宽25.4 m,分3孔,单孔净宽6.4m,检修闸门为平面叠梁门.出口节制闸为开敞式钢筋混凝土整体式结构,长20 m,宽25.4 m,分3孔,单孔净宽6.4m,节制闸设工作闸门和检修闸门.工作闸门为弧形门,液压启闭.检修闸门设在工作闸门下游,为平面叠梁门.
A Holocene Yalu River-derived fine-grained deposit in the southeast coastal area of the Liaodong Peninsula

High-resolution seismic profiles and surface samples were studied in detail in order to determine the structures, provenance, and dynamic mechanisms of a fine-grained deposit in the southeast coastal area of the Liaodong Peninsula, China. Results indicate that there is a prominent fine-grained deposit distributed alongshore up to 14 m thick, which thins out to less than 2 m in both seaward and landward directions, forming an Ω-shaped pattern of cross-section. The deposit is 180–300 km away from the Yalu River mouth and extends along the southeast coast of the Liaodong Peninsula between the northeast of Dalian Bay and southwest of the Changshan Islands, in water depths of 20–40 m. The deposit, which is mainly derived from the Yalu River, represents a Holocene Highstand System Tract sequence formed since the highest sea level around 7.0 ka. The Yalu River-derived sediments were redeposited in the area off the southeast coast of the Liaodong Peninsula after resuspension and transportation by the Liaonan Coastal Current
Geostrophic meridional transport in tropical Northwest Pacific based on Argo profiles

Absolute geostrophic currents in the North Pacific Ocean were calculated using P-vector method from newly gridded Argo profiling float data collected during 2004–2009. The meridional volume transport of geostrophic currents differed significantly from the classical Sverdrup balance, with differences of 10×10~6–20×10~6 m~3 /s in the interior tropical Northwest Pacific Ocean. Analyses showed that errors of wind stress estimation could not explain all of the differences. The largest differences were found in the areas immediately north and south of the bifurcation latitude of the North Equatorial Current west of the dateline, and in the recirculation area of the Kuroshio and its extension, where nonlinear eddy activities were robust. Comparison of the geostrophic meridional transport and the wind-driven Sverdrup meridional transport in a high-resolution OFES simulation showed that nonlinear effects of the ocean circulation were the most likely reason for the differences. It is therefore suggested that the linear, steady wind-driven dynamics of the Sverdrup theory cannot completely explain the meridional transport of the interior circulation of the tropical Northwest Pacific Ocean
五官科门诊医院感染存在的危险因素及对策

基层医院五官科门诊条件有限,眼耳鼻喉均在一个诊室内,患者相对集中,存在许多医院感染危险因素。为了减少和控制医院感染的发生,笔者采取了相应的对策。
脑源性神经营养因子经Akt/eNOS通路在大鼠蛛网膜下腔出血后早期脑损伤中的表达

目的检测脑源性神经营养因子(brain derived neurotrophic factor,BDNF)在蛛网膜下腔出血(sub arachnoid hemorrhage,SAH)后早期脑损伤(early brain injury,EBI)中的表达,初步探讨其促进内皮细胞新生的机制及通路,为SAH患者的治疗提供新方法。方法健康雄性SD大鼠72只,随机分为假手术组(sham组)和SAH后12h、24h、48h组,每组各18只。视交叉前池注血法建立大鼠SAH模型,RT-PCR、Western Blot分别检测各组大鼠BDNF、VEGF和内皮型一氧化氮合酶(endothelial nitric oxide synthase,eNOs)mRNA及总蛋白,并测量各组大鼠脑含水量。结果大鼠SAH后12h海马中BNDF和VEGF mRNA和蛋白质含量开始明显增高,并于24h达到高峰,48h开始下降,但仍明显高于假手术组,并且其表达量相互之间成正相关(rBV=0.973,P=0.014)。大鼠脑含水量亦于出血后12h明显增高,24h达到高峰,48h后仍保持较高水平。BDNF蛋白表达量与脑含水量变化呈正相关(r=0.947,P=0.023)。同时还发现eNOs mRNA和蛋白质含量同样于24h达到高峰,48h开始下降,但仍明显高于假手术组,并与BNDF和VEGF的表达成正相关(r_(NV)=0.964,P=0.021;r_(BN)=0.948,P=0.016)。结论BDNF可能在SAH后脑缺血缺氧的修复病理过程中起了十分重要的作用,并且很可能是通过调控PI_3K/Akt/eNOS途径增加VEGF的表达以发挥作用。
吴茱萸热敷在腹腔镜结直肠癌外科快速康复中的应用

目的探讨吴茱萸热敷及快速康复在腹腔镜结直肠癌外科中对胃肠功能的影响.方法选取外科行腹腔镜结直肠癌根治术后患者154例,随机分为4组:吴茱萸+快速康复组、快速康复组、传统方法康复组、吴茱萸+传统方法康复组,对其进行治疗,观察其胃肠功能恢复情况.结果在术后胃动素水平、血管活性肠肽水平、主观的胃肠功能恢复评价3个方面,吴茱萸+快速康复组与快速康复组比较差异均无统计学意义(P>0.05),余组比较差异均有统计学意义(P<0.05).结论吴茱萸热敷在传统方法康复治疗措施中,可起到促进胃肠功能恢复的作用,而在快速康复治疗中未能体现出明显效果;快速康复在胃肠功能恢复中的体现明显优于传统方法康复治疗.
乳腺癌血管生成靶向治疗策略的研究进展

乳腺癌是导致妇女死亡最常见的恶性肿瘤之一,死亡比例占所有妇女癌症的17%,死亡率居女性各类恶性肿瘤的首位.在美国,每3例诊断为恶性肿瘤的女性患者中就有一例是乳腺癌.而在我国,乳腺癌的发病率正逐年增加且趋于年轻化.手术、化疗、放疗及内分泌治疗常可取得较好的治疗效果,但仍有25%~30%的早期乳腺癌患者在随访10~15年之后发生远处转移.侵袭和转移是乳腺癌患者死亡的主要原因,而肿瘤新生血管的形成是导致肿瘤浸润和转移的一个重要因素.20世纪70年代FOLKMAN提出,实体性肿瘤的生长、转移都依赖肿瘤新生血管的生成,并为肿瘤的治疗提供了新的靶点,这一观点已经被大量实验结果所证实.因此以肿瘤新生血管为靶点的生物治疗成为研究热点.本文将对乳腺癌抗血管生成靶向治疗的研究进展作一综述.
女性肛管雌、孕激素受体的表达与痔的关系

目的研究绝经前后女性患者肛管性激素受体表达与其痔病严重程度的相关性.方法选择接受痔切除术(Miligan- Morgan)患者128例,分为绝经组和未绝经组,每组64例.分别在术前行体格检查并评估其痔病严重程度.切除的标本送病理检查并检测其雌激素受体(ER)和孕激素受体(PR)的表达,然后对两组间阳性率进行对比.结果绝经组与未绝经组ER阳性率分别为20.3%和56.3%(P<0.01),PR阳性率在两组间分别为15.6%和50.0%(P<0.01).再根据痔病严重程度将所有研究对象分成Ⅲ度和Ⅳ度组:Ⅲ度组患者ER阳性率为30.2%,而Ⅳ度组阳性率为62.5%(P<0.01),而PR在两组间的阳性率分别为24.0%和65.6%(P<0.01).未绝经患者中,痔病为Ⅲ度的ER阳性率为52.0%,Ⅳ度的ER阳性率71.4%(P=0.195),而PR阳性率在Ⅲ度和Ⅳ度组分别为46.0%和64.3%(P=0.226).绝经患者中,痔病为Ⅲ度和Ⅳ度的ER阳性率各为17.4%和27.8%(P=0.560),而PR阳性率在两组间为15.2%和16.7%(P=1.000).结论女性肛管ER及PR水平与患者是否绝经及痔病严重度存在一定的相关性,女性性激素对痔病的发生发展或起到一定作用.
托烷司琼对运动病患者恶心综合征的防治作用

目的探讨托烷司琼对旋转刺激所致的恶心综合征的防治效果,为研究海上环境下术后恶心呕吐防治方案提供依据.方法采用旋椅试验制备运动病临床模型.120例患者随机均分为3组(n=40):对照组,只旋转,不用药;预防组,先静脉注射托烷司琼5 mg,10 min后行旋转刺激;治疗组,先行旋转刺激,旋转结束后即刻静脉注射托烷司琼5 mg.观测指标包括:生命体征及熵指数,恶心综合征的发生率、开始时间、持续时间,恶心分级及视觉模糊评分(visual analogue scale,VAS),胃电图检测等.结果旋转后对照组、预防组、治疗组恶心综合征发生率分别为87.5%、22.5%和82.5%,预防组显著低于对照组和治疗组(P<0.01),持续时间和VAS值分别为(13.64±4.65)min、(2.59±3.07)min、(8.73±4.87)min和(4.86±1.42)分、(1.32±1.25)分、(3.27±1.37)分,预防组<治疗组<对照组,组间差异有统计学意义(P<0.01).旋转后对照组和治疗组正常胃慢波百分比显著降低,胃动过速波百分比、主频、主功率及主频不稳定系数均显著增加,预防组仅主频不稳定系数显著增加.对照组、预防组和治疗组正常胃慢波百分比分别为(53.75±10.85)%、(79.38±9.92)%和(65.66±10.25)%,预防组>治疗组>对照组;胃动过速波百分比和主频不稳定系数分别为(31.16±9.24)%、(12.26±8.42)%、(22.79±9.20)%和(32.29±8.77)%、(18.14±7.30)%、(25.45±8.49)%,预防组<治疗组<对照组,组间差异均有统计学意义(P<0.01).结论托烷司琼可明显减轻旋转刺激所致的恶心综合征,预防性应用效果更好.
血栓栓塞颈内动脉兔脑缺血模型的建立与评价

目的建立和评价血栓栓塞颈内动脉制备兔脑缺血模型.方法兔随机分为血栓栓塞组和线栓栓塞组,每组10只.所有动物术前行家兔头颅CT平扫.血栓栓塞组:结扎颈总动脉到颈内动脉路程中的主要分支颈外动脉(保留7~10 mm)和翼腭动脉,从颈外动脉置管取血,退出导管,体外向血液中加入凝固酶,制作自体血栓栓子,再次通过颈外动脉置管导入栓子,形成颈内动脉栓塞,术后1h行颈内动脉CT血管成像,术后12 h行动物行为学(肌张力)评分,术后24 h行兔颅脑CT平扫,保留影像资料和数据.线栓栓塞组:同样结扎颈外动脉和翼腭动脉,在颈总动脉分叉处,打开颈内动脉,置入长度20 mm 4-0尼龙线异物栓子,同血栓栓塞组一样评估参数.结果血栓栓塞组和线栓栓塞组比较,术后1h CTA血栓栓塞组发现3只颈内动脉内有血栓栓子,而线栓栓塞组则未发现明显颈内动脉内栓子形成;术后12 h动物生物学行为评估两者差异无统计学意义(P>0.05),术后24 h家兔颅脑CT检查发现梗死灶深度血栓栓塞组较线栓栓塞组明显增大(P<0.05).术后7 d两组死亡率比较差异无统计学意义(P>0.05).结论自体血栓栓子颈内动脉栓塞技术可制作稳定动物动脉栓塞模型,梗死范围及位置确切,可为脑缺血再灌注研究及血栓后再通技术和药物的实验提供基础.
Novel chiral C_2-symmetric multidentate aminophosphine ligands for use in catalytic asymmetric reduction of ketones

A series of novel chiral C2-symmetric multidentate aminophosphine ligands have been successfully synthesized by Schiff-base condensation of bis(o-formylphenyl)phenylphosphane and easily available monoprotected(1R,2R)-diaminocyclohexane.The catalytic properties of these ligands were investigated in Ir-catalyzed asymmetric transfer hydrogenation of various aromatic ketones,giving the corresponding optical active alcohols with up to 98%conversion and good ee under mild reaction conditions.
银屑灵中芍药苷在大鼠组织中分布研究

目的建立HPLC测定大鼠组织样品中芍药苷质量浓度的方法,并进行组织分布研究,为银屑灵开发奠定基础。方法大鼠灌胃给药,Kinetex C_(18)色谱柱(2.6μm,4.6 mm×100 mm),流动相为甲醇-乙腈-0.5%乙酸(20∶5∶75)梯度洗脱。体积流量1.2 mL/min;检测波长275 nm;柱温30℃。结果该法测定芍药苷在组织中1.6~160μg/mL线性关系良好,各组织方法回收率均在92.3%~109.5%内,提取回收率均大于78%,组织中芍药苷质量浓度从高到低依次为肝>肾>脾>肺>心>脑。结论该方法准确、灵敏度高,服用银屑灵后芍药苷主要分布脏器为肝脏。
基于血液酒精浓度和脑电特征的酒后驾车事故倾向对比研究

为研究驾驶员不同程度饮酒后的交通事故倾向,结合步进酒后状态诱发和模拟驾驶实验,对比分析了驾驶员血液酒精浓度BAC和规范化脑电δ波功率增益NPG分别与交通事故倾向NAP之间的数值关系。实验结果显示:饮入酒精导致约92%驾驶员安全驾驶能力下降,但约8%驾驶员在适量酒精作用下反而有所提高,说明血液酒精浓度方案缺乏一定的严谨性;NPG与NAP之间普遍存在增减一致性,而BAC与NAP在约10%~30%主观最大饮酒量区间可能增减不一致。规范化脑电δ波功率增益相比于血液酒精浓度能更准确的反映驾驶员不同程度饮酒后的交通事故倾向,可作为酒后驾车相关问题及对策研究的一种新型参数依据。
~(18) F-FDG PET/CT与增强CT诊断腹部肿瘤腹腔转移的对比研究

腹腔淋巴结及脏器是腹部肿瘤转移的常见部位,对其进行准确评估是制定最佳治疗方案的前提。~(18)F-FDG PET/CT显像以葡萄糖代谢差异作为诊断依据,通过图像融合技术精确定位,能提高肿瘤诊断的准确性,但也存在一定的假阳性与假阴性。本研究通过52例肿瘤患者术前~(18) F-FDG PET/CT及增强CT检查结果与术后病理检查结果比较,评价~(18) F-FDG PET/CT在诊断腹部肿瘤腹部淋巴结及脏器转移中的价值。
The structure of prion: is it enough for interpreting the diverse phenotypes of prion diseases?

Prion diseases, or transmissible spongiform encephalop athies, are neurodegenerative diseases, which affect human and many species of animals with 100% fatality rate. The most accepted etiology for prion disease is 'prion', which arises from the conversion from cellular PrP~C to the patho logical PrP~(Sc). This review discussed the characteristic structure of PrP, including PRNP gene, PrP~C, PrP~(Sc), PrP amyloid, and prion strains.
Sediment Trapping from Hyperconcentrated Flow as Affected by Grass Filter Strips

To evaluate the effect of vegetative filter strips on sediment trapping, the spatial distribution of deposited sediment, and the size distribution of deposited particles from hyperconcentrated flows, a simulated grass filter strip experiment was conducted with plastic grass using an adjustable slope steel flume. The simulated vegetation cover was 36%, and the inflow sediment concentrations applied were 147, 238, 320, and 429 kg m~(-3). The sediment concentration in the outflow, and the sediment particle size were determined. The results showed that the grass filter strips trapped most of the sediment from inflow at low sediment concentration. The deposition efficiency decreased with increasing sediment concentration, being 55.2% and 15.7% in the 147 and 429 kg m~(-3) sediment treatments, respectively. Most of the deposited sediments were distributed in the upper flume. In addition, the grass filter strips mainly trapped the coarse sediment (particle size > 10 μm).
Soil Salinity Changes in the Jordan Valley Potentially Threaten Sustainable Irrigated Agriculture

The integrated effect of irrigation and agricultural practices on soil salinity in the Jordan Valley (JV), where over 60% of Jordan’s agricultural produce is grown, was investigated in this study during 2009-2010. Due to the differences in agricultural operations, cropping patterns, irrigation management, and weather conditions, 206 top- and sub-soil samples were taken every 1 to 3 km from representative farms along a north-south (N-S) transect with 1 to 2 km lateral extents. Soil electrical conductivity of saturated extract (EC_(se)), Ca, Mg, K, Na, Cl, and Na adsorption ratio (SAR) were determined in saturated paste extracts. Results indicated that about 63% of soils in the JV are indeed saline, out of which almost 46% are moderately to strongly saline. Along the N-S transect of the JV, EC_(se) increased from 4.5 to 14.1 dS m~(-1) in top-soil samples. Similar increase was observed for the sub-soil samples. The major chemical components of soil salinity; i.e., Ca, Mg, and Cl, also showed a similar increase along the N-S transect of the valley. Moreover, compared to previous field sampling, results showed that changes in soil salinity in the JV were dramatic. In addition, it was found that Cl imposed an existing and potential threat to sensitive crops in 60% of the soils in the JV, where Cl concentrations were greater than 710 mg L~(-1). Under the prevalent arid Mediterranean conditions, improving the management of irrigation water, crops, and nutrient inputs and increasing water and fertilizer use efficiencies should be indispensable to conserve and sustain the already fragile agricultural soils in the JV.
Influence of Copper on Transport and Dissipation of Lambda-Cyhalothrin and Cypermethrin in Soils

Repeated applications of bordeaux mixture (a blend of copper sulfate and calcium hydroxide) and pyrethroid insecticides (Pys) have led to elevated copper (Cu) and Pys concentrations in vineyard surface soils. To understand the potential influence of Cu on the fate of Pys in the soil environment, we selected two Pys, cypermethrin (CPM) and lambda-cyhalothrin (λ-CHT), and two typical Chinese vineyard soils, Haplic Acrisol and Luvic Phaeozem, as experimental samples. The dissipation experiment was conducted at room temperature in the dark, and the transport of both Pys through the soils was investigated using soil thin-layer chromatography. The results showed that the transport of Pys in both soils increased as the Cu~(2+) concentration increased from 0 to 100 mg L~(-1), and Pys were more transportable in Haplic Acrisol (HA) than in Luvic Phaeozem (LP) under the same experimental conditions. For CPM, only 100 mg L~(-1) of Cu~(2+) significantly (P <0.05) increased Pys transport through both soils relative to water. Lambda-CHT was significantly (P < 0.05) transported through HA by all the Cu~(2+) concentrations compared to water, and all but the 1 mg L~(-1) of Cu~(2+) significantly (P < 0.05) increased the transport of λ-CHT through LP relative to water. However, the dissipation rates of CPM and λ-CHT decreased with the addition of Cu to soils. Our findings suggest that the risk of groundwater contamination by Pys increases in the soils with elevated Cu concentrations.