mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Rock burst mechanism analysis in an advanced segment of gob-side entry under different dip angles of the seam and prevention technology

In order to investigate the frequent occurrences of rock burst in gob-side entry during the mining process of the mining zone No. 7, the mechanical model of main roof of fully-mechanized caving mining before breaking was established by the Winkler foundation beam theory, and the stress evolution law of surrounding rock with different dip angles of the seam during the mining process was analyzed by using FLAC3D. The results show that: with the dip angle changing from 45° to 0°, the solid-coal side of gobside entry begins to form an L-shaped stress concentration zone at a dip angle of 30°, and the stress concentration degree goes to higher and higher levels. However, the stress concentration degree of the coalpillar side goes to lower and lower levels; the influence range and peak stress of the abutment at the lateral strata of adjacent gob increase with dip angle decreasing and reach a maximum value at a dip angle of 0℃, but the tailgate is not affected; the abutment pressure superposition of two adjacent gobs leads to stress concentration further enhancing in both sides of gob-side entry. With the influence of strong mining disturbance, rock burst is easily induced by dynamic and static combined load in the advanced segment of gob-side entry. To achieve stability control similar to that in the roadway, the key control strategy is to reinforce surrounding rock and unload both sides. Accordingly, the large-diameter drilling and high-pressure water injection combined unloading and reinforced support cooperative control technology was proposed and applied in field test. The results of Electromagnetic Emission (EME) and field observation showed that unloading and surrounding rock control effect was obvious.
Groundwater monitoring of an open-pit limestone quarry: Water-rock interaction and mixing estimation within the rock layers by geochemical and statistical analyses

Water-rock interaction and groundwater mixing are important phenomena in understanding hydrogeological systems and the stability of rock slopes especially those consisting largely of moderately watersoluble minerals like calcite. In this study, the hydrogeological and geochemical evolutions of groundwater in a limestone quarry composed of three strata: limestone layer (covering), interbedded layer under the covering layer, and slaty greenstone layer (basement) were investigated. Water-rock interaction in the open-pit limestone quarry was evaluated using PHREEQC, while hierarchical cluster analysis (HCA) and principal component analysis (PCA) were used to classify and identify water sources responsible for possible groundwater mixing within rock layers. In addition, Geochemist's Workbench was applied to estimate the mixing fractions to clarify sensitive zones that may affect rock slope stability. The results showed that the changes in Ca~(2+) and HCO_3~- concentrations of several groundwater samples along the interbedded layer could be attributed to mixing groundwater from the limestone layer and that from slaty greenstone layer. Based on the HCA and PCA results, groundwaters were classified into several types depending on their origin: (1) groundwater from the limestone layer (LO), (2) mixed groundwater flowing along the interbedded layer (e.g., groundwater samples L-7, L-11, S-3 and S-4), and (3) groundwater originating from the slaty greenstone layer (SO). The mixing fractions of 41% LO: 59% SO, 64% LO: 36% SO, 43% LO: 57% SO and 25% LO: 75% SO on the normal days corresponded to groundwaters L-7, L-11, S-3 and S-4, respectively, while the mixing fractions of groundwaters L-7 and L-11 (61% LO: 39% SO and 93% LO: 7% SO, respectively) on rainy days became the majority of groundwater originating from the limestone layer. These indicate that groundwater along the interbedded layer significantly affected the stability of rock slopes by enlarging multi-breaking zones in the layer through calcite dissolution and inducing high water pressure, tension cracks and potential sliding plane along this layer particularly during intense rainfall episodes.
Statistical analysis of distribution patterns of coal seams in fold zones in Northwest China

The mechanisms for rock bursts occurrences in fold zones are complex, and the redistribution of in-situ stresses is closely related to the complexity of the structures. Analysis of the geomorphology of fold structures and changes of coal thickness can help identify zones prone to rock bursts to improve safety and productivity in coal mines. This study investigated the distribution characteristics of fold structures in coal seams in fold zones in four mines in northwest China. Geometrical characteristics of fold structures in coal seams and changes of coal thickness were analysed, based on comprehensive evaluation indexes, such as the length–width ratio of folds, interlimb angle, ratio P1 of projected width of fold limbs to that of the hinge zone, curvature ratio P2, the maximum curvature and amplitude. The statistical analysis of the four coal mines shows that the length–width ratio of folds changed from 0.78 to 2.03 and the maximum curvature of cross sections of folds was less than 0.04. The curvature ratio of cross section of a fold in the structure was no more than 1.4 and the interlimb angles of cross sections of 89% of folds were larger than 150°. Gentle fold structures were dominant and the specific geological morphologies were domes or basins. The isopleth of coal thickness above the coal mines showed a fluctuation trend similar to the contour line of the floor of coal seams. The coal thickness in an anticline area was smaller than that in the neighboring syncline area. Therefore, the overall variation of coal thickness in the mining areas was likely to have a relation with the direction of the regional principal stress.
Dynamic failure risk of coal pillar formed by irregular shape longwall face: A case study

Irregular shape workface would result in the presence of coal pillar, which leads to high stress concentration and possibly induces coal bumps. In order to study the coal bump mechanism of pillars, static and dynamic stress overlapping (SDSO) method was proposed to explain the impacts of static stress concentration and tremors induced by mining activities. The stress and deformation in surrounding rock of mining face were analyzed based on the field case study at 1303 workface in Zhaolou Coal Mine in China. The results illustrate that the surrounding rock of a workface could be divided into four different zones, i.e., residual stress zone, stress decrease zone, stress increase zone and original stress zone. The stress increase zone is prone to failure under the SDSO impact loading conditions and will provide elastic energy for inducing coal bump. Based on the numerical modelling results, the evolution of static stress in coal pillar as the size of gob increasing was studied, and the impact of dynamic stress was investigated through analyzing the characteristics of tremor activities. The numerical results demonstrate the peak value of vertical stress in coal pillar rises from about 30 MPa with mining distance 10 m to 52.6 MPa with mining distance 120 m, and the location of peak stress transfers to the inner zone of coal pillars as the workface moves forward. For the daily tremor activities, tremors with high energy released indicate high dynamic stress disturbance on the surrounding rock, therefore, the impact of dynamic stressing is more serious during workface extension period because the tremor frequency and average energy after workface extension are higher than those before the workface extension.
A numerical simulation study on mechanical behaviour of coal with bedding planes under coupled static and dynamic load

To investigate the bedding influence on coal mechanical behaviour in underground environments such as coal or rock burst, simulations of dynamic SHPB tests of pre-stressed coal specimens with different bedding angles were carried out using a particle flow code 2-dimensional (PFC2D). Three impact velocities of 4, 8 and 12 m/s were selected to study dynamic behaviours of coal containing bedding planes under different dynamic loads. The simulation results showed that the existence of bedding planes leads to the degradation of the mechanical properties and their weakening effect significantly depends on the angle θ between the bedding planes and load direction. With θ increaseing from 0° to 90°, the strength first decreased and subsequently increased and specimens became most vulnerable when h was 30° or 45°. Five failure modes were observed in the specimens in the context of macro-cracks. Furthermore, energy characteristics combined with ultimate failure patterns revealed that maximum accumulated energy and failure intensity have a positive relation with the strength of specimen. When bedding planes were parallel or perpendicular to loading direction, specimens absorbed more energy and experienced more violent failure with increased number of cracks. In contrast, bedding planes with θ of 30° or 45° reduced the specimens' ability of storing strain energy to the lowest with fewer cracks observed after failure.
How relevant are engineering samples in the management of personal dust exposure?

A directive, legislated by the South African Department of Minerals and Energy (DME) in 1997, was introduced to reduce the dust exposures of continuous miner (CM) operators to below 5 mg/m3, when measured at the operator's cab position. The focus of this paper is to review the effectiveness of observing this rule for almost two decades and discuss industry perceptions arising from the application of this rule. The results have demonstrated that the engineering sample cannot predict the personal shift dust exposure of a CM operator. Therefore, it is recommended that the engineering sampling, as currently practiced, should be reviewed with the objective to discontinue and replace it by the approved PDM3700 realtime dust monitor.
Evaluating geological and geotechnical data for the study of land subsidence phenomena at the perimeter of the Amyntaio coalmine, Greece

Land subsidence phenomena caused by the overexploitation of the aquifers require the holistic knowledge of the geological, tectonic, hydrogeological and especially the geotechnical conditions of the affected sites in order to be mitigated. The current paper focuses on the study of the phenomena taking place at the Amyntaio sub-basin, northern Greece, hosting the homonymous open pit coal mine, operating there the last two decades. The mining as well as the rising agriculture activities have led to a significant drawdown of the ground water level triggering extensive ground subsidence phenomena, causing damages at the nearby villages, infrastructure and farmlands. The production and evaluation of engineering geological–geotechnical maps as well as of thematic tectonic and hydrogeological maps proved that the knowledge of this data is crucial for the interpretation of the land subsidence mechanism and the spatial distribution of its effects.
Strength and deformation behaviors of bedded rock mass under bolt reinforcement

The mechanism of bolt support is an important topic in mining engineering and slope treatment. The artificial material and loading system were self-developed to study the influence of bedding cohesion and bolt number on the anchoring behavior of bedded rock mass. The results show that, both peak strength and elasticity modulus increase gradually with the increase of bedding cohesion and bolt number. The axial stress–strain curve of bedded rock mass under the reinforcement of bolts presents the features of strain-softening and secondary strengthening. Finally, anchoring behavior of bedded rock mass with different bolt numbers was simulated by using FLAC3D numerical program and the results were compared with the experimental results. This study can provide certain bases to the stability control and support design of bedded rock mass in roadway.
Improved hemimorphite flotation using xanthate as a collector with S(II) and Pb(II) activation

The flotation of hemimorphite using the S(II)–Pb(II)–xanthate process, which includes sulfidization with sodium sulfide, activation by lead cations, and subsequent flotation with xanthate, was investigated. The flotation results indicated that hemimorphite floats when the S(II)–Pb(II)–xanthate process is used; a maximum recovery of approximately 90% was obtained. Zeta-potential, contact-angle, scanning electron microscopy–energy-dispersive spectrometry(SEM–EDS), and diffuse-reflectance infrared Fourier transform spectroscopy(DRIFTS) measurements were used to characterize the activation products on the hemimorphite surface and their subsequent interaction with sodium butyl xanthate(SBX). The results showed that a ZnS coating formed on the hemimorphite surface after the sample was conditioned in an Na2S solution. However, the formation of a ZnS coating on the hemimorphite surface did not improve hemimorphite flotation. With the subsequent addition of lead cations, PbS species formed on the mineral surface. The formation of the PbS species on the surface of hemimorphite significantly increased the adsorption capacity of SBX, forming lead xanthate(referred to as chemical adsorption) and leading to a substantial improvement in hemimorphite flotation. Our results indicate that the addition of lead cations is a critical step in the successful flotation of hemimorphite using the sulfidization–lead ion activation–xanthate process.
Leaching behavior of V, Pb, Cd, Cr, and As from stone coal waste rock with different particle sizes

This paper investigates the leaching behavior of heavy metals(V, Pb, Cd, Cr, and As) from stone coal waste rocks with various particle sizes using dynamic leaching experiments. The results show that the dissolved concentrations of V and As initially increased and then slightly decreased as time progressed and that the dissolved concentrations of Pb, Cd, and Cr were high in the early stage before decreasing. The particle size of the stone coal waste rocks strongly influenced the heavy metal concentration in the leaching solutions. The effects of the particle size of the stone coal waste rocks on the dissolved concentrations of V, Pb, and As decreased in the order fine fraction > medium fraction > coarse fraction, and the effects of particle size on the dissolved concentrations of Cr and Cd decreased in the order medium fraction > coarse fraction > fine fraction and coarse fraction > medium fraction > fine fraction, respectively. The quantities of heavy metals dissolved from the stone coal waste rock with fine particle sizes were observed to decrease in the order V(17104.36 μg/kg) > As(609.41 μg/kg) > Pb(469.24 μg/kg) > Cr(56.35 μg/kg) > Cd(27.52 μg/kg), and the dissolution rates decreased in the order As(2.96%) > Pb(0.93%) > V(0.35%) > Cd(0.25%) > Cr(0.01%). The specific surface area, pore size of the stone coal waste rocks, and chemical forms of heavy metals also influenced the release of heavy metals from the stone coal waste rocks. Kinetic analysis showed that the dissolution of heavy metals fundamentally agreed with the rate equation controlled by the shrinking core model. The results of this study are expected to serve as a reference for the evaluation of heavy metals contamination from stone coal waste rocks.
Wandering Minds with Wandering Brain Networks

The default mode network (DMN) is associated with the occurrence of mind-wandering or task-unrelated thought.In contrast,the frontal-parietal network (FPN) and visual network (VS) are involved in tasks with external stimuli.However,it is not clear how these functional network interactions support these two different processes - mind-wandering and on-task - especially with regard to individual variation in the mind-wandering experience.In this study,we investigated the functional connectivity and modular structure among the DMN,FPN,and VS.Our results showed that,compared to the on-task period,mindwandering was associated with increased DMN activity and increased DMN-VS connectivity.Moreover,mindwandering was accompanied by a large number of transitional nodes,which expressed a diversity of brain regions.Intriguingly,the functional connectivity of the FPN and VS was strongly correlated with individual behavioral performance.Our findings highlight the individual variation of mind-wandering,which implies the importance of other complementary large-scale brain networks.
Identification and characterization of novel fusion genes in prostate cancer by targeted RNA capture and next-generation sequencing

Gene fusions play critical roles in the development and progression of prostate cancer, and have been used as molecular biomarkers for diagnosis of the malignant disease. To further explore the novel fusions in prostate cancer, we performed targeted RNA capture and next-generation sequencing in a cohort of 52 prostate cancer patients, identified and validated 14 fusion events (7 types of fusion genes) in 12 cases, including three novel fusion genes. We characterized a chromosome rearrangement-induced trigenic KLK2-DGKB-ETV1 fusion, which may function as a noncoding RNA to upregulate the expression of the wild-type ETV1 protein in the tumor tissue. Additionally, we detected two novel fusion forms of HNRNPA2B1-ETV1 and SLC45A2-AMACR fusions, respectively. Interestingly, fusion events participated by kinase genes, which frequently occurred in other human cancers, were not present in these prostate cancer cases, suggesting discrepant gene fusion patterns in different cancers. These findings expand the genetic spectrum of prostate cancer and provide insight into diagnosis of this prevalent disease.
Gallic acid inhibits fibroblast growth and migration in keloids through the AKT/ERK signaling pathway

Keloids are a fibroproliferative disorder of the skin resulted from abnormal healing of injured or irritated skin and are characterized by the ability to spread beyond the original boundary of the wound. Here, we tested the effect of gallic acid (GA), a plant polyphenol with selective growth inhibitory effects in cancer, on the proliferation and invasion of keloid fibroblasts (KFs) isolated from patients undergoing surgery. GA inhibited KF proliferation, migration, and invasion in parallel with the downregulation of matrix metalloproteinase-1 and-3 and upregulation of tissue inhibitors of metalloproteinase-1. Flow cytometric analysis showed that GA inhibited cell cycle progression and induced apoptosis. The effects of GA on KFs occurred in parallel with the inhibition of AKT and ERK1/2, suggesting that GA acts by suppressing the AKT/ERK signaling pathway. In ex vivo explant cultures of keloid tissues, GA inhibited the migration of KFs to the wound area and suppressed the expression of angiogenic markers concomitant with the inhibition of collagen deposition. These results identify GA as a potential therapeutic agent for the treatment of keloids and suggest a potential mechanism underlying its protective effect.
Properties of Renewable Biocomposite from Poly(butylene succinate) and Teakwood Sawdust before and after Accelerated Weathering Condition

A new kind of renewable biocomposite was prepared by compounding bio-based poly(butylene succinate) (PBS) with teakwood sawdust which sieved sawdust were used as received or treated with 3-aminopropyltriethoxy silane (APS). The PBS/teakwood composites were compounded in the weight ratio of 90/10 wt%, 80/20 wt%, 70/30 wt% and 60/40 wt%. Thermal properties and morphology of the composites were investigated. The accelerated weathering testing was carried out for 60 h under water spraying and cycle of UV exposure at 60 °C. Tensile and flexural properties before and after the accelerated weathering condition were analyzed. It was found that teakwood sawdust did not effect on the melting temperatures of PBS but reduced the degree of crystallinity. The composites showed lower thermal stability due to the degradation of hemicellulose and silane. Interfacial adhesion between PBS and APS-treated teakwood sawdust was achieved showing less pull-out of sawdust. Tensile and flexural modulus of composites increased with respect to sawdust content, in which the APS-treated composites had higher modulus. After passing the accelerated weathering condition, tensile modulus of the composites slightly increased while flexural properties decreased in the composites added sawdust content higher than 20 wt%. Loss of flexural properties was more pronounced than tensile properties due to the hydrolytic degradation introduced by hydrophilicity of lignocellulosic fillers.
1例男男性行为者HIV-1抗体不确定结果的追踪报告

艾滋病病毒(HIV)蛋白印迹试验(WB)中出现“不确定”的结果具有一定的比例。有研究表明,HIV抗体确证试验结果“不确定”样本的检出数量和比例越来越高,HIV抗体确证试验结果不确定转归的结果不同。但近年来男男性行为者(MSM)中不确定检测结果越来越多地提示,病人可能处于急性感染期。本文就1例经集合核酸定性检测(HIV Pooled PCR)阳性,后多次进行WB和病毒载量(VL)随访检测,最终被WB确认“HIV-1抗体阳性”并进行早期治疗的MSM病例。报告如下。
ERRα/PGC-1α介导的信号通路在妇科恶性肿瘤中的研究进展

雌激素相关受体α(estrogen-related receptorα,ERRα)属核受体家族成员,是一类非配体依赖性激活的孤儿核受体,ERRα受到转录共活化因子过氧化物酶体增殖物受体γ共活化因子-1α(peroxisome proliferator-activated receptor γ coactivator-1α,PGC-1α)的活性调节,参与了细胞增殖、分化发育、癌变、胞内信号传导等过程。近年来多项研究表明ERRα/PGC-1α与肿瘤细胞的能量代谢、血管形成、侵袭转移等过程密切相关,但其在妇科恶性肿瘤中的具体作用机制尚不明确。本文就ERRα/PGC-1α信号参与妇科恶性肿瘤发生机制的研究进展进行综述。旨在为临床后续的抗肿瘤治疗提供理论依据。
卡铂腹腔化疗在晚期卵巢癌治疗中的应用

卵巢癌是引起女性死亡最常见的生殖道恶性肿瘤,治疗以手术和以铂类为基础的化疗为主。卡铂是卵巢癌治疗中最常用的铂类药物,腹腔化疗广泛应用于治疗晚期卵巢癌,但关于卡铂腹腔化疗的报道较少,亦有一定争议。本文就卡铂用于腹腔化疗的研究现状及存在问题进行综述。
中国骨折内固定术后感染诊断与治疗专家共识(2018版)

近年来,随着社会经济的高速发展,各类创伤因素所致四肢骨折的患者日趋增多,接受内固定治疗的患者也逐年增加,由于患者伤情复杂多变,加上临床医生对患者自身感染高危因素认识的不足,导致骨折内固定术后感染患者的数量也在不断增加。目前,国内仍缺乏相应的诊疗共识,本着遵循科学性、先进性及实用性的原则,经中华医学会骨科学分会创伤骨科学组、中华医学会骨科学分会外固定与肢体重建学组、中国医师协会创伤外科医师分会创伤感染专家委员会和中国医师协会骨科医师分会创伤专家工作委员会成员讨论一致通过,制定本共识。
Real-Time Pricing for Smart Grid with Multiple Companies and Multiple Users Using Two-Stage Optimization

In this paper,we focus on the real-time interactions among multiple utility companies and multiple users and formulate real-time pricing (RTP) as a two-stage optimization problem.At the first stage,based on cost function,we propose a continuous supply function bidding mechanism to model the utility companies' profit maximization problem,by which the analytic expression of electricity price is further derived.At the second stage,considering that individually optimal solution may not be socially optimal,we employ convex optimization with linear constraints to model the price anticipating users' daily payoff maximum.Substitute the analytic expression of electricity price obtained at the first stage into the optimization problem at the second stage.Using customized proximal point algorithm (C-PPA),the optimization problem at the second stage is solved and electricity price is obtained accordingly.We also prove the existence and uniqueness of the Nash equilibrium in the mentioned twostage optimization and the convergence of C-PPA.In addition,in order to make the algorithm more practical,a statistical approach is used to obtain the function of price only through online information exchange,instead of solving it directly.The proposed approach offers RTP,power production and load scheduling for multiple utility companies and multiple users in smart grid.Statistical approach helps to protect the company's privacy and avoid the interference of random factors,and C-PPA has an advantage over Lagrangian algorithm because the former need not obtain the objection function of the dual optimization problem by solving an optimization problem with parameters.Simulation results show that the proposed framework can significantly reduce peak time loading and efficiently balance system energy distribution.
品管圈护理干预对患者健康行为及护理人员技能素质的影响

探究基于品管圈建立的护理干预对患者健康行为及护理人员技能素质的影响。2017年1月南京市江宁区中医医院护理部实施基于品管圈建立的护理干预,实施前后护理人员均50人,对比实施前后患者健康行为及护理人员技能素质等情况。结果显示,实施后患者住院时间、健康行为、自我效能、满意度评分均优于实施前,差异有统计学意义(t=4.671、6.354、5.412、4.541,均P=0.000)。实施后,护理人员责任感、仪表文明、沟通配合、服务态度、质控管理均高于实施前,差异有统计学意义(t=7.895、8.541、 6.523、4.587、7.541,均P=0.000)。基于品管圈建立的护理干预,能够改善患者健康行为及生活质量,提高护理人员技能素质。
李佃贵教授治疗胃癌经验

从胃癌的病因病机及治法用药规律等方面总结李佃贵教授治疗胃癌经验。李教授首创浊毒理论,倡导化浊解毒法,并在其基础上主张分期治疗、病症结合,巧用虫药、攻守相辅,重视脾胃、生化有源的诊疗思路,为中医治疗胃癌提供新思路,并附医案1侧。