mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Phonon-Limited Electron Mobility in Single-Layer MoS_2

The dynamics of electron transport in single-layer MoS_2 is simulated by employing the single particle Monte Carlo method. Acoustic phonon scattering, optical phonon scattering and Frohlich scattering are taken into account. It is found that the electron mobility decreases from 806 cm~2 /V.s for a transverse electrical field of 10~3 V/m to 426/112cm~2/V.s for a transverse electrical field of 10~5/10~7 V/m. Further detailed analysis on carrier dynamics reveals that the low field mobility is dominated by the acoustic phonon scattering while the role of optical phonon scattering is to relax the electron energy below the optical phonon energy by efficient energy relaxation through optical phonon emission. Only when the transverse electrical field is larger than 10~6 V/m, the mobility can be determined by the optical phonon scattering, leading to a strong mobility degradation.
Effect of Time Delay on Binary Signal Detection via a Bistable System

The effect of time delay on binary signal detection via a bistable system in the presence of white or colored Gaussian noise is investigated. By defining the bit error rate based on the solution of the approximated Fokker-Planck equation, the detector performance is investigated theoretically and is verified by Monte Carlo simulation. It is shown that, when the system parameter or noise intensity is optimally chosen, the increasing time delay generally improves the system performance. It is also shown that it is more difficult to accurately predict the system performance with a larger time delay and correlation time. This may inspire more thorough investigations in cooperative effects of a nonlinear system and time delay on signal processing.
Room-Temperature Magnetism Realized by Doping Fe into Ferroelectric LiTa03

We synthesize LiTa_(1-x)Fe_x O_(3-σ) (LTFO) ceramics by the conventional solid-state reaction method. The samples remain single phase up to x = 0.09. The magnetic measurements show that the doping of Fe successfully realizes ferromagnetism of LTFO at room temperature. The dielectric measurements indicate that LTFO is ferroelectric, similarly to LiTaO_3 (LTO), but its ferroelectric Curie temperature seems to decrease with the increasing Fe content. By means of doping Fe ions into LTO, the coexistence of spontaneous electric polarization and spontaneous magnetic moment is realized at room temperature.
Strain Induced Metastable Phase and Phase Revolution in PbTiO_3-CoFe_2O_4 Nanocomposite Film

An inter-component epitaxial strain-induced PbTiO_3 metastable phase is observed in a PbTiO_3-CoFe_2O_4 epitaxial composite film, corresponding to the dielectric anomaly reported previously. High-resolution synchrotron radiation X-ray diffraction and first principles calculation demonstrate the coexistence of different PbTiO_3 phases, even a possible morphotropic phase boundary in the fiim, elucidating the underlying microscopic mechanism of the formation of PbTiO_3 metastable phase. This sheds light on the design and manipulation of electromechanical properties of epitaxial films, through the strain engineering.
Numerical Simulation of Droplets Impacting on a Liquid Film with a Vapor Bubble Growing

A numerical model of multiphase flow is developed to investigate the relative contributions of droplet parameters to spray cooling heat transfer. The 2-D model takes into account the effects of surface tension, gravity and viscosity. The heat and mass exchanges of free surface are defined to study vapor bubble behavior in liquid films. The multiphase flow and heat transfer are discussed for the three droplet parameters: initial droplet position, initial droplet temperature, and droplet impact frequency. The heat transfer mechanisms of the three cases are discussed in detail.
A TDG/CBP/RARa Ternary Complex Mediates the Retinoic Acid-dependent Expression of DNA Methylation-sensitive Genes

The thymine DNA glycosylase (TDG) is a multifunctional enzyme, which is essential for embryonic development. It mediates the base excision repair (BER) of G:T and G:U DNA mismatches arising from the deamination of 5-methyl cytosine (5-MeC) and cytosine, respectively. Recent studies have pointed at a role of TDG during the active demethylation of 5-MeC within CpG islands. TDG interacts with the histone acetylase CREB-binding protein (CBP) to activate CBP-dependent transcription. In addition, TDG also interacts with the retinoic acid receptor a (RARa), resulting in the activation of RARa target genes. Here we provide evidence for the existence of a functional ternary complex containing TDG, CBP and activated RARa. Using global transcriptome profiling, we uncover a coupling of de novo methylation-sensitive and RA-dependent transcription, which coincides with a significant subset of CBP target genes. The introduction of a point mutation in TDG, which neither affects overall protein structure nor BER activity, leads to a significant loss in ternary complex stability, resulting in the deregulation of RA targets involved in cellular networks associated with DNA replication, recombination and repair. We thus demonstrate for the first time a direct coupling of TDG’s epigenomic and transcription regulatory function through ternary complexes with CBP and RARa.
某高校给水管网改造工程方案设计

针对某高校目前存在管网能耗浪费、供水水质较差的问题，提出了分区供水的管网改造方案，即低压区利用原市政管网余压供至建筑低层，高压区利用水库泵站提升供水至建筑高层。对改造管网系统进行了不同工况下的平差计算，计算结果表明最不利点水压满足最小供水压力10 m 的要求。改造后的管网系统能够有效利用市政管网余压，节约了大量电耗和水耗费用，同时进一步提高了学校供水水质安全。
居住建筑同层排水应用中的关键技术研究与对策

同层排水在国内应用过程中，由于各种原因，出现了地漏返溢、防水层破坏而引起地面和临近房间底部墙面的渗水、卫生间异味等问题。从同层排水形式的阐述着手，探讨了同层排水在居住建筑内应用时，如何把控同层排水关键技术的节点，提高同层排水系统的可靠性，并提供了切实有效的技术措施。
戈壁地区建设工程配套职工生活区给排水设计

戈壁地区建设工程配套职工生活区给排水工程，受戈壁地区特殊环境影响，其形式不同于内地常规小区给排水设计，需结合戈壁自身条件，探索适合戈壁环境的给排水设计方法。对其职工生活区的工程选扯、给水系统、排水系统、热水系统、消防系统、构筑物、管材敷设等设计进行总结、探讨，供同类工程设计参考。
使用赛默飞iCAP 7600 ICP-OES进行超快速农业土壤分析

不断加强的经济和环境压力促使种植业采用高新技术来加速植物生长并提高产量.农民采用的技术之一是定向施肥，该技术可以确保不同的营养素按照土壤实际缺少情况和需要施入，同时产生最少的废弃物.该过程需要对土地进行取样，然后通过全球定位卫星（Global Positioning Satellites ，以下简称GPS ）对样品坐标进行标记.对这些土壤样品进行营养素信息的分析，并将结果上传至GPS系统，引导肥料分布系统将正确的土壤营养素配方输送至准确的位置，从而营造理想的生长条件.
Dynamic and Static Recrystallization Behaviour of Coarse-grained Austenite in a Nb-V-Ti Microalloyed Steel

The dynamic recrystallization (DRX) and static recrystallization (SRX) behaviour of coarse-grained austenite in a Nb-V-Ti microalloyed steel were studied by using a Gleeble thermomechanical simulator. Continuous and interrupted compression tests of coarse-grained austenite were performed in the temperature range of 1000-1150 ℃ at a strain rate of 0.1-5 s~(-1). The peak and critical strains for the onset of DRX were identified with strain hardening rate analysis, and the ratio of critical strain to peak strain was found to be consistent with the one reported for fine-grained austenite. An equation of the time for 50% softening was proposed by considering the activation energy of steel without microalloying elements and the solute drag effect of microalloying elements. Strain-induced precipitation may not take place at the deformation temperature above 1000 ℃, which indicates that SRX of coarse-grained austenite is mainly retarded by coarse grain size and Nb in solution during rough rolling.
Mechanism of Strength Improvement of Magnetite Pellet by Adding Boron-bearing Iron Concentrate

The mechanism of improving compressive strength of magnetite pellet by adding boron-bearing iron concentrate was studied. Boron-bearing iron concentrate and magnetite were mixed, pelletized and roasted under different roasting conditions. Then, compressive strength of pellets was tested, and polished sections of the roasted pellets were analyzed from the perspective of mineralogy. Finally, the effects of different proportions, roasting temperatures and roasting time of boron-bearing iron concentrate on the compressive strength of magnetite pellets were investigated and explained.
流域“自然-社会”二元水循环理论框架

流域水循环的“自然-社会”二元演变是导致近年来水问题和水危机的本质原因.实现缺水地区供用水、水环境、水生态安全的国家目标，必须依靠以流域水循环为统一基础的水资源科学调控，其首要的科学基础是对高强度人类活动干扰下的流域水循环与水资源演变的内在机理及其规律的认知.本文从我国二元水循环演进历史、流域二元水循环理论、典型流域水资源演变规律、流域二元水循环模式与概念模型4个方面进行探讨，为变化环境下水循环的基本认知模式、现代环境下水资源衰减规律等提供研究参考.
贺兰山地区震旦系碳酸盐岩碳氧同位素分析

对宁夏贺兰山地区出露的震旦系碳酸盐岩进行了详细的野外地质调查和碳氧同位素分析测试，发现该地区震旦系正目观组碳酸盐岩碳同位素表现出一定的变化规律：由北到南的几条典型剖面中δ13C值自下向上均逐渐减小，变化范围都集中在-4.51‰~0.11‰。，最大负偏值达到了-6.88‰.兔儿坑组中发现的宏体生物化石在华南灯影组中部出现，从而将正目观组和兔儿坑组的形成时代限定在震旦纪.冰川的发育导致了极端寒冷的气候，海洋中有机质大幅降低，δ13C值出现普遍的负偏.兔儿坑组代表了冰期的结束，生物的复苏，海洋中有机物含量增加.通过与全球其他地区同期地层碳氧同位素分布的投图对比，发现正目观组冰期沉积的形成时间可能晚于Gaskiers冰期，研究其为探讨埃迪卡拉纪华北板块的古海洋、古地理环境和生物演化起了重要作用，为全球同期地层碳氧同位素数据库提供了新的补充.
新疆阿拉塔格地区新元古代花岗片麻岩的锆石U-Pb定年与Hf同位素：对中天山地块前寒武纪地壳演化的制约

中天山地块前寒武纪结晶基底的组成和形成历史，是揭示天山造山带构造演化的关键问题.本文对分布在中天山地块阿拉塔格地区的花岗片麻岩进行了 LA-ICP-MS锆石U-Pb 年代学和LA-MC-ICPMS锆石Hf同位素研究.两个研究样品中的岩浆结晶锆石分别获得了945±6和942±6 Ma的原岩形成年龄，揭示了阿拉塔格地区存在新元古代早期的岩浆活动. 这些岩浆结晶锆石的Hf模式年龄远大于其结晶年龄，分别为1.82?2.22和1.70?2.03 Ga,反映了它们的岩浆均起源于古老地壳的再造.但是这一古元古代的Hf模式年龄很可能是新元古代地壳中不同时代古老地壳物质混合的结果.在这两个花岗片麻岩中还获得了989?1617 Ma的继承碎屑锆石年龄，它们具有变化较大的锆石Hf同位素组成，模式年龄为1.54~2.30 Ga,且部分1.4~1.6Ga锆石具有接近亏损地幔的~(176)Hf/~(177)Hf初始值，反映了中元古代时期在中天山地块存在新生地壳形成和古老地壳再造事件，显示出与塔里木克拉通显著不同的前寒武纪地壳形成和演化历史.中天山地块的前寒武纪地壳基底可能并不是来自塔里木克拉通的一部分.
温热刺激对bcr/abl融合基因阳性的慢性粒细胞白血病细胞gp96转录水平的影响

目的探讨温热刺激对bcr/abl融合基因阳性的慢性粒细胞白血病(chronic myeloid leukemia,CML)细胞 gp96转录水平的影响,为CML热疗研究提供理论基础。方法通过骨髓涂片对初选患者进行诊断,荧光原位杂交(FISH)技术检测bcr/abl融合基因,采集病例血细胞分为4组,对照组采用37℃温热刺激30 min,试验组分别经40℃、42℃、44℃进行温热刺激各30min,采用RT-PCR技术检测gp96 mRNA的转录水平。结果骨髓涂片表现为 CML骨髓像,FISH检测bcr/abl融合基因阳性。温热刺激后,随着刺激温度的提高,gp96的转录水平也升高。结论在CML病例中开展热疗,可能通过gp96参与的机体免疫调节,有助于病情的缓解。
影响气候系统模式温室气体敏感度的反馈过程-- 基于FGOALS 模式的研究

气候系统模式对特定温室气体的敏感度对未来气候变化的预估结果至关重要.为理解影响气候模式对温室气体敏感度的关键反馈过程，本文利用瞬间4倍CO_2强迫试验，研究了LASG/IAP两个版本的气候系统模式FGOALS-s2和FGOALS-g2的气候响应.将全球平均地表气温(SAT)的变化作为衡量气候模式响应的主要标准.根据SAT的响应随时间的变化趋势，将150年的试验结果分为两个时段:前20年为快响应阶段，后130年为慢响应阶段.采用国际通用的Gregory方法分别估计4倍CO_2引起的辐射强迫和平衡态气候敏感度. 结果表明，FGOALS-s2中水汽的响应偏强使估算的CO_2辐射强迫比FGOALS-g2强7.1%. 平衡态气候敏感度定义为2倍CO_2强迫下达到新的平衡态时全球平均SAT 的变化，其在FGOALS-s2和FGOALS-g2中分别约为4.5和3.7 K，前者较之后者偏强21.6%. FGOALS-s2敏感度大是由于快响应阶段的水汽和反照率正反馈过程偏强，表现为水汽含量的增加和海冰的减少均太快. 在慢响应阶段，尽管FGOALS-s2的水汽及反照率正反馈仍然较强，但FGOALS-s2的总负反馈强于FGOALS-g2，这是因为FGOALS-s2中云短波负反馈更强，补偿了其较弱的晴空负反馈. FGOALS-s2中云短波负反馈偏强主要是由于总云量以及云水路径正响应过强. 云短波反馈的不确定性是总反馈不确定性的主要来源.
日本M_w9.0大地震激发全球地震波传播特性的数值模拟研究与对比分析

2011年3月11日日本东北部海域发生M_w9.0级特大地震，并诱发海啸.本文利用Centroid Moment Tensor(CMT)震源机制解作为震源项，以地震波传播理论为基础，基于横向各向同性PREM地球模型，考虑地表地形及海洋等地球特性，利用谱元法结合高性能并行计算，对日本大地震激发的地震波传播特性进行了数值模拟研究.计算结果显示了全球地震波的传播形态.将数值模拟结果与理论模型的走时曲线和实际观测数据进行拟合对比，验证了模拟结果的可靠性和可行性.分别就考虑海洋和不考虑海洋两种数值模型下的地震波传播特性进行了对比分析.结果显示，海洋的存在对地震波强地面运动存在明显的影响.海洋会使P波运动位移峰值和速度峰值相对较小;海洋对S波的影响较复杂，不考虑海洋效应时使得位移和波速随时间推移迅速减小.因此，对沿海地区的地震灾害评估应该考虑海洋效应. 此外，考虑地球重力因素情况下，对数值计算得到的2004年印尼苏门答腊地震、2008年汶川地震及2011年日本福岛大地震激发的球型场和环型场特征进行对比研究，通过对功率谱密度结果的观察并与理论值的对比分析，可以清晰的看到三个大地震释放的能量有很明显的不同，同时认识到数值模拟结果可以较准确重现长周期理论频率值，主要表现在0T2~0T13的环型振型及0S7~0S31的球型振型. 结果显示数值模拟方法可以成功的用于地球自由振荡研究，未来可以作为一个主要工具深入探讨地球的横向不均匀性等特性对地球自由振荡特性的影响.
高血氨大鼠服用乳酸菌后焦虑降低和认知功能改善

相关证据表明, 高血氨(HA)引发的神经炎和五羟色胺(5-HT)系统异常可能是导致肝性脑病(HE)认知功能下降和焦虑症状的原因. 服用益生菌可能是治疗HE神经精神症状的有效措施, 因为益生菌在维护免疫系统平衡和调节5-HT 系统活动中发挥了重要的作用. 检验了益生菌瑞士乳杆菌NS8改善HA 大鼠认知功能下降和焦虑行为的有效性. 通过连续4周的腹腔注射醋酸铵造成Sprague-Dawley 大鼠的高血氨. 然后让HA大鼠每日饮用添加了瑞士乳杆菌NS8(10_9 CFU/mL)的饮水. Morris 水迷宫测试大鼠的认知功能, 高架十字测试大鼠的焦虑行为. 脑区神经炎的程度以炎性标记物诱导型一氧化氮合酶、前列腺素E2和白介素1β 的水平表示. 5-HT 系统的活动以5-HT,5-HIAA(5-HT 的代谢物)以及色氨酸(5-HT 的前体物质)的水平表示. 益生菌处理显著地降低了HA大鼠的神经炎程度, 减少了5-HT 系统的活动, 改善了认知功能和焦虑行为. 这些结果说明, 服用益生菌瑞士乳杆菌NS8是治疗HA 大鼠认知功能下降和焦虑的有效方法.
猪伪狂犬病病毒载体重组疫苗研究进展

猪伪狂犬病病毒(Pseudorabies virus,PRV)又名猪疱疹病毒I 型(Suid herpesvirus type I), 属于疱疹病毒科(Herpesviridae)甲亚科(Alphaerpesvirinae)水痘病毒属(Varicellovirus),为线状双股DNA 病毒,全长约150 kb,含有77个读码框,平均G+C 含量高达73.6 %。PRV 由独特的长区段(UL)和短区段(US)及位于US 两侧的末端重复序列(TR)和内部重复序列(IR)所组成, 即形成了UL-IR-US-IR 结构。
心电图学系列讲座(二)---心脏解剖与传导系统

心脏是维系生命的重要器官,了解心脏的解剖结构与传导系统特点是学习和掌握心电图的基础,了解心脏与肺的解剖关系,有助于理解肺部疾病影响心脏、引起心电图的相应改变; 了解左心与食管的解剖关系,有助于理解食管心电图、食管心房调搏检查的意义; 了解房室解剖关系,有助于理解房性期前收缩、室性期前收缩的形态、定位及起搏器安置部位; 了解冠状动脉的走行、分布及供血部位,有助于心肌缺血、损伤、梗死的定位诊断; 了解心脏传导系统,有助于理解窦房阻滞、房内阻滞、房室阻滞、室内阻滞的机制和心电图特点; 了解心脏附加传导束,有助于理解预激综合征波形改变和形成房室折返性心动过速的机制。
关节置换围手术期镇痛研究进展

骨性关节炎作为一种临床常见疾病,尤其多发于老年人,60岁以上人群的患病率高达50%。关节置换是治疗各种关节终末期疾病的终极有效方法,疗效确切,已在临床中广泛开展且呈逐年递增趋势。如何控制关节置换围手术期疼痛达到早期功能锻炼,进而提升术后功能已成为当前骨科医师所面临的重大课题。长期以来国内外学者对此做出了多方面的努力,本文就目前关节置换围手术期镇痛的研究现状作一综述。
粘液性水肿昏迷1例报告(一个易被遗忘的引起昏迷的原因)

粘液性水肿昏迷是甲状腺功能减退症(甲减)少见的合并症,从1953年至今,随着对本病认识水平的提高,先后不少作者陆续介绍了同样的病例。Urbanic 等统计,在美国10 y内住院的甲状腺功能减低的患者中,昏迷发生率仅占0. 1%,但该病死亡率很高,是需要紧急处理的内分泌急症。该疾病早期识别比较困难,若能及时诊断、治疗可以挽救生命。现将我院急诊室诊断粘液性水肿昏迷并治疗成功的1例病例报道如下。
Hydrothermal synthesis of single-crystal CeCO_3OH and their thermal conversion to CeO_2

Hexagonal single-crystalline cerium carbonate hydroxide (CeCO_3OH) precursors with dendrite morphologies have been synthesized by a facile hydrothermal method at 180°C using CeCl_3-7H_2O as the cerium source, triethylenetetramine as both an alkaline and carbon source, with triethylenetetramine also playing an important role in the formation of the dendrite structure. Polycrystalline ceria (CeO_2) have been obtained by calcining the precursor at 500°C for 4 h. The morphology of the precursor was partly maintained during the heating process. The optical absorption spectra indicate the CeO_2 nano/microstructures have a direct band gap of 2.92 eV, which is lower than values of the bulk powder due to the quantum size effect. The high absorption in the UV region for CeO_2 nano/microstructure indicated that this material was expected to be used as UV-blocking materials.
Copper-catalyzed Ullmann-type synthesis of diaryl ethers assisted by salicylaldimine ligands

A series of salicylaldimine ligands were designed to promote the copper-catalyzed Ullmann crosscoupling reaction. After a screening process, 2-((2-isopropylphenylimino)methyl)phenol was found to serve as a good supporting ligand for this reaction. Employing this Schiff-base ligand as a new supporting ligand, the copper-catalyzed coupling reactions of aryl bromides and aryl iodides with various phenols successfully proceeded in good yields under mild conditions. Various diaryl ethers were obtained with excellent yields in dioxane in the presence of K3PO4 and a catalytic amount of copper(I) salt.
Facile one-pot synthesis of PEGylated monodisperse mesoporous silica nanoparticles with controllable particle sizes

In this work, we describe the one-pot synthesis of PEGylated mesoporous silica nanoparticles (MSNs) with uniform shape, tunable sizes, and narrow size distributions. The size of these nanoparticles can be controlled from 49 nmto 98 nmby simply varying the concentration of triethanolamine during the basecatalyzed sol-gel reaction. Particles were characterized by transmission electron microscopy, dynamic light scattering, Fourier transform infrared spectrometry, thermogravimetric analysis, and nitrogen adsorption-desorption measurements. These PEGylated MSNs exhibited excellent long-term stability in biological media, which ensures their potential applications in drug delivery.
2D Naphthalenedisulfonate-cadmiun coordination polymer with 2,4,5-tri(4-pyridyl)-imidazole as a co-ligand: Structure and catalytic property

A new 2D coordination polymer, [Cd(tpim)(1,5-nds)]n (1), was constructed from 1,5-naphthalenedisulfonate (1,5-nds), 2,4,5-tri(4-pyridyl)-imidazole (tpim) and Cd(CH_3COO)_2-2H_2O, which can be subsequently used to promote the epoxide ring-opening reaction of epoxides and amines with remarkable catalytic activity. In addition, the thermal and luminescent properties of 1 in the solid state were also investigated.
苏州大学2006-2013年国家自然科学基金资助项目情况与管理经验分析

苏州大学是国家“211工程”重点建设高校、“2011计划”首批认定高校，是江苏省属重点综合性大学，其主要前身为全国最早创建的现代高等学府之一的东吴大学，目前已有110余年的历史。长期以来，苏州大学实施“顶天立地”科技创新战略，坚持人才强校，质量强校，文化强校，依托“长三角”地区雄厚的经济实力和优越的人文、地域条件，努力将学校建设成为具有学科、区域和国际化特色的国内一流、国际知名的高水平研究型大学，成为区域内高水平创新人才培养、高新技术研究、高层次决策咨询的重要基地，引领区域经济、社会和文化的发展。
慢性光化性皮炎发病机制和治疗研究进展

慢性光化性皮炎是一种与光照射有关的光敏性皮肤病,其发病机制尚未完全明确,可能与迟发型超敏反应、免疫功能紊乱、光敏物质及紫外线照射等有关。治疗主要为避光和去除光敏物,局部用糖皮质激素和钙调磷酸酶抑制剂,口服烟酰胺、羟氯喹、β-胡萝卜素及光疗等有效。严重病例系统用糖皮质激素、免疫抑制剂及手术治疗。
鲁东晚白垩世中-晚期恐龙多样性事件: 恐龙蛋化石提供的证据

山东省东部地区上白垩统王氏群恐龙蛋化石记录表明, 以长形蛋类为代表的恐龙种群从晚白垩世中期一直生存到晚期, 但是以网形蛋类和圆形蛋类为代表的恐龙种群在晚白垩世中期灭绝了, 以椭圆形蛋类为代表的新恐龙种群则在晚白垩世晚期出现. 计算这些类型蛋壳的水蒸气传导率, 发现圆形蛋类和网形蛋类的水蒸气传导率比长形蛋类和椭圆形蛋类的高4~115倍, 说明前者必须在更为潮湿环境中进行孵化. 根据蛋壳的d~(18)O记录, 从晚白垩世中期到晚期, 气候的变化是由湿润变为较干燥的气候环境. 可以认为, 气候环境的变化是引起这一恐龙多样性事件的原因.
胃乃安新制剂对水浸束缚应激性胃溃疡的药效作用

目的:观察胃乃安新制剂对水浸束缚应激性胃溃疡的作用及其作用机制。方法:在应激性胃溃疡模型下,从肉眼观察、病理切片、透射电镜三个层面评价胃乃安新制剂对水浸束缚应激性胃溃疡的药效,并检测胃组织的丙二醛、超氧化物歧化酶水平以探讨胃乃安可能的作用机制。结果:与模型组比较,肉眼观察及病理切片评分结果表明,高剂量组、雷尼替丁组均有抗应激性胃溃疡效果(P<0.01),且新制剂抗溃疡效果呈剂量依赖性关系;透射电镜观察结果表明新制剂可明显逆转主细胞、壁细胞的超微结构损伤性改变;新制剂可降低胃组织MDA含量,升高SOD活性。结论:胃乃安新制剂对水浸束缚应激性胃溃疡有显著抗损伤作用,其机理可能与抗氧化,清除自由基有关。
氮、磷、钾肥不同配比对甘草主要有效成分含量的影响研究

目的:通过研究N、P、K肥料不同配比对甘草药材中主要成分甘草苷和甘草酸含量的影响,以明确利于甘草药材中甘草苷和甘草酸形成的最佳N、P、K肥配比。方法:采用N、P、K单因素完全随机设计和“3414”肥料效应试验设计进行田间小区试验。结果:N、P、K单因素完全随机设计中,两年生甘草中甘草苷和甘草酸N、P、K肥料配比最优者分别是无P区和NPK区;三年生甘草中甘草苷和甘草酸N、P、K肥料配比最优者分别是无肥区和无N区。“3414”肥料效应试验中,得到最佳三元二次肥料效应方程,且两年生甘草中甘草苷及甘草酸在施肥料为N_(16)P_0K_4和N_0P_8K_4得到的含量较高;三年生甘草中甘草苷及甘草酸在施肥料为N_(16)P_4K_4、N_(24)P_8K_4和N_(16)P_8K_0时得到的含量较高。结论:“3414”肥料效应试验中,两年生甘草中甘草苷及甘草酸在施肥料为N_0P_8K_4时得到的含量最高;三年生甘草中甘草苷及甘草酸在施肥料为分别N_(16)P_8K_0和N_(16)P_4K_4时得到的含量最高。
State of the art and practice of pavement anti-icing and de-icing techniques

Pavement snow and icing are worldwide problems, but effective countermeasures are just beginning to be developed in China. The two most common snow and ice removal methods are mechanical clearance and chemical melting, and the advantages and disadvantages of each approach are discussed here, including environmental and structural damage caused by corrosive snow melting agents. New developments in chemical melting agents and mechanical equipment are discussed, and an overview of alternative thermal melting systems is presented, including the use of geothermy and non-geothermal heating systems utilizing solar energy, electricity, conductive pavement materials, and infrared/microwave applications. Strategic recommendations are made for continued enhancement of public safety in snow and ice conditions.
Mild hypothermia for treatment of diffuse axonal injur y:a quantitative analysis of diffusion tensor imaging

Fractional anisotropy values in diffusion tensor imaging can quantitatively relfect the consistency of nerve ifbers after brain damage, where higher values generally indicate less damage to nerve ifbers. Therefore, we hypothesized that diffusion tensor imaging could be used to evaluate the effect of mild hypothermia on diffuse axonal injury. A total of 102 patients with diffuse axonal injury were randomly divided into two groups:normothermic and mild hypothermic treatment groups. Patient’s modiifed Rankin scale scores 2 months after mild hypothermia were signiifcant-ly lower than those for the normothermia group. The difference in average fractional anisotropy value for each region of interest before and after mild hypothermia was 1.32-1.36 times higher than the value in the normothermia group. Quantitative assessment of diffusion tensor imaging indicates that mild hypothermia therapy may be beneifcial for patients with diffuse axonal injury.
Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis

AIM: To investigate the chemical constituents of Dioscorea zingiberensis C. H. Wright. METHODS: The compounds were isolated by various chromatographic techniques, and the structures of the new steroidal sapo-nins were elucidated by extensive 1D- and 2D-NMR, MS, and IR spectral analysis. RESULTS: The 70% EtOH extract of the rhizomes of Dioscorea zingiberensis afforded two new steroidal saponins, zingibereno-sides A (1) and B (2), along with eight known analogues, 3β, 26-dihydroxy-25(R)-furosta-△~(5, 20(22))-diene-3-O-α-L- rhamnopyra-nosyl-(1→2)-O-β-D-glucopyranoside (3), methyl parvifloside (4), deltoside (5), methyl deltoside (6), zingiberensis new saponin (7), deltonin (8), progenin III (9) and diosgenin-diglucoside (10). CONCLUSION: Two new steroidal saponins were isolated from Dioscorea zingiberensis and their structures determined.
Inhibitory effect of medicinal plant-derived carboxylic acids on the human transporters hOAT1, hOAT3, hOATP1B1, and hOATP2B1

A significant number of organic carboxylic acids have been shown to influence the absorption and distribution of drugs mediated by organic anion transporters (OATs). In this study, uptake experiments were performed to assess the inhibitory effects of cinnamic acid, ferulic acid, oleanolic acid, deoxycholic acid, and cynarin on hOAT1, hOAT3, hOATP1B1, and hOATP2B1. After a drug-drug interaction (DDI) investigation, cinnamic acid, ferulic acid, deoxycholic acid, and cynarin were found and validated to inhibit hOAT1 in a competitive manner, and deoxycholic acid was found to be an inhibitor of all four transporters. The apparent 50% inhibitory concentrations of cinnamic acid, ferulic acid, deoxycholic acid, and cynarin were estimated to be 133.87, 3.69, 90.03 and 6.03 μmol?L~(-1) for hOAT1, respectively. The apparent 50% inhibitory concentrations of deoxycholic acid were estimated to be 9.57 μmol?L~(-1) for hOAT3, 70.54 μmol?L~(-1) for hOATP1B1, and 168.27 μmol?L~(-1) for hOATP2B1. Because cinnamic acid, ferulic acid, and cynarin are ingredients of food or food additives, the present study suggests there are new food-drug interactions to be disclosed. In addition, deoxycholic acid may be used as a probe for studying the correlation of OATs and OATPs.
Comparison of anti-bacterial activity of three types of di-O-caffeoylquinic acids in Lonicera japonica flowers based on microcalorimetry

The anti-bacterial activities of three types of di-O-caffeoylquinic acids (diCQAs) in Lonicera japonica flowers, a traditional Chinese medicine (TCM), on Bacillus shigae growth were investigated and compared by microcalorimetry. The three types of diCQAs were 3, 4-di-O-caffeoylquinic acid (3, 4-diCQA), 3, 5-di-O-caffeoylquinic acid (3, 5-diCQA), and 4, 5-di-O-caffeoylquinic acid (4, 5-diCQA). Some qualitative and quantitative information of the effects of the three diCQAs on metabolic power–time curves, growth rate constant k, maximum heat-output power Pm, and the generation time tG, total heat output Q_t, and growth inhibitory ratio I of B. shigae were calculated. In accordance with a thermo-kinetic model, the corresponding quantitative relationships of k, P_m, Qt, I and c were established. Also, the half-inhibitory concentrations of the drugs (IC_(50)) were obtained by quantitative analysis. Based on the quantity–activity relationships and the IC_(50) values, the sequence of inhibitory activity was 3, 5-diCQA > 4, 5-diCQA > 3, 4-diCQA. The results illustrate the possibility that the caffeoyl ester group at C-5 is the principal group that has a higher affinity for the bacterial cell, and that the intramolecular distance of the two caffeoyl ester groups also has an important influence on the anti-bacterial activities of the diCQAs.
Antimagic Labeling of Generalized Pyramid Graphs

An antimagic labeling of a graph withq edges is a bijection from the set of edges to the set of positive integers{1,2,...,q}such that all vertex weights are pairwise distinct,where the vertex weight of a vertex is the sum of the labels of all edges incident with that vertex.A graph is antimagic if it has an antimagic labeling.In this paper,we provide antimagic labelings for a family of generalized pyramid graphs.
保护草原生态、建设美丽牧区

在举国上下认真贯彻落实十八大精神,特别是在十八届三中全会即将召开的前夕,业界的精英们汇集一堂,共议"保护草原生态、建设美丽牧区"大计,意义重大,影响深远。在此,我对本次论坛的顺利召开表示热烈的祝贺!对长期以来关心支持中国草原事业发展的各位领导、各位专家、各位代表表示衷心的感谢!
轧机浊环水系统排泥优化工程实例

介绍了某钢铁生产线浊环水系统污泥排除情况的改善,由于此类污泥含油量大,发现使用板框压滤机效果不佳,之后将其废弃,改为通过调节池进行污泥回流及增设污泥浓缩的方法,提高了系统的污泥排出量,降低了出水SS,其污泥排出率达98%~99%,出水SS低于20mg/L,取得了良好的社会和经济效益。
携带感觉神经岛状穿支皮瓣修复褥疮的疗效观察

目的总结携带感觉神经岛状穿支皮瓣修复褥疮的疗效。方法2006年3月-2011年3月,采用携带感觉神经岛状穿支皮瓣修复16例(17处)褥疮。男6例,女10例;年龄20~87岁,平均62.2岁。病程3.5个月~6年,中位病程12个月。褥疮部位:骶尾部11处,坐骨结节4处,大转子2处。创面范围4cm×4cm~14cm×8cm。术中切取皮瓣范围6.0cm×4.5cm~12.0cm×9.0cm。供区直接拉拢缝合。结果术后15个皮瓣顺利成活,创面Ⅰ期愈合;2个皮瓣发生远端局部坏死,经清创、换药后愈合。供区切口均Ⅰ期愈合。患者住院时间22~58d,平均37d。患者均获随访,随访时间11~46个月,平均15个月。皮瓣色泽、弹性良好。末次随访时,皮瓣感觉恢复7例,感觉迟钝5例,无感觉5例。褥疮均无复发。结论携带感觉神经岛状穿支皮瓣修复褥疮为受区的感觉恢复提供了可能。