mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
肉芽肿性乳腺炎中医综合治疗与手术治疗的回顾性队列研究

目的评价肉芽肿性乳腺炎(GM)中医综合治疗与手术治疗的疗效,为选择合理治疗方式提供依据。方法收集2005年9月至2012年9月在广州中医药大学第二附属医院行中医综合治疗与手术治疗的GM 患者病例资料,进行回顾性队列研究。结果符合纳入标准的患者94例,中医综合疗法治疗40例,治愈38例(95%),好转2例(5%) ;复发3例(7.5%);西医手术治疗54例,治愈51例(94.4%) ,好转3例(5. 6%) ;复发4例(7.4%) 。两种治疗方法疗效及复发率无显著性差异(P > 0. 05) ,但手术组治疗时间明显短于中医综合治疗组(P < 0. 01) ,中医综合治疗组乳房外形评价优良,明显好于手术治疗组(P < 0. 05) 。结论采用以外治法为主的中医综合疗法治疗GM,具有损伤范围小,能保持乳房外形等优点,是临床值得推广的中医特色疗法。
灵芝对正常小鼠免疫功能作用的研究

目的研究灵芝对正常小鼠免疫功能的影响。方法通过小鼠迟发型变态反应、ConA 诱导小鼠脾淋巴细胞转化试验、血清溶血素抗体生成试验、小鼠腹腔巨噬细胞吞噬鸡红细胞试验、小鼠碳粒廓清试验等方法,测定灵芝对正常小鼠免疫功能的影响。结果灵芝能显著有效的增强正常Balb /c 小鼠迟发型变态反应免疫、抗体生成免疫、单核-巨噬细胞免疫能力以及NK 细胞活性,促进小鼠血清溶血素产生。结论灵芝能够从细胞免疫功能、体液免疫功能、单核-巨噬细胞功能、NK 细胞活性等多个方面达到增强正常小鼠免疫系统功能的作用,从而发挥其滋补强壮,扶正固本的功效。
宫颈脱落细胞DNA倍体分析技术及质量控制

细胞DNA倍体分析法是一项用于肿瘤早期诊断的新技术,该技术将Feulgen染色法与计算机图像分析技术相结合。Feulgen染色对显示细胞核DNA含量既精确又具有一定的特异性,其原理是利用硫堇等染料对细胞核DNA产生特异性着色;细胞核着色的深浅代表DNA含量的多少,将着色强弱不等的细胞核通过自动扫描显微镜转化为光密度值(IOD),通过计算机及显微图像分析技术进行整合、处理。
39例慢性乙型肝炎及相关性慢加急性肝衰竭患者多基因区变异位点分析

HBV感染是目前全球范围内公共卫生问题,每年因HBV所导致的肝硬化、肝衰竭以及肝细胞癌而死亡的人口达到了100万。肝衰竭是内科危重症,病情进展迅速,病死率高,其发病机制尚未完全明了,内科无特效治疗手段,且费用昂贵,在其众多发病原因中,HBV活动和变异为最主要的病因。本研究旨在通过对20例乙型肝炎相关性慢加急性肝衰竭患者以及19例慢性乙型肝炎(CHB)患者血清HBV多个基因区的PCR扩增、测序,进一步分析其基因型及各个基因区变异位点,以了解HBV变异与乙型肝炎相关性慢加急性肝衰竭之间的关系及规律。
糖尿病合并肝病的机制及其处理对策

临床上,愈来愈多的患者同时存在糖尿病(diabetes mellitus,DM)和肝病。慢性肝病合并DM既可能为一个病因的两个系统的不同表现,又可能是具有相互促进的链式恶性循环;DM和肝脏损伤可互相影响导致彼此疾病顽固难治,使得患者生活质量下降和预期寿命缩短。为此,有必要探讨高血糖与肝脏损伤之间的相互关系及其发病机制,从而制定针对性的防治及随访策略以改善此类患者的预后。
慢性脑供血不足的中西医研究现状

我国65岁以上的老年人已达1.35亿,占全国人口的10%,且13.6%的老人患有脑血管疾病。由于脑血管疾病的死亡率、复发率、致残率都非常高,故该病已经成为威胁老龄人群的第一杀手。随着生活节奏的加快,在有抽烟、酗酒、喜爱高盐、高糖和高脂饮食不良生活习惯的人群中,80%存在罹患脑血管疾病的潜在危险。慢性脑供血不足(CCCI)是国内外近10年提出的较新病名,以脑动脉循环障碍引起的,以头晕头痛失眠健忘等为主症,但临床表现和影像学检查未发现血管性器质性脑病变的一种疾病; 是中老年的常见病多发病,是脑卒中痴呆等疾病发生发展过程中的重要环节,据统计中老年人群中有2/3的人患有此病,如果不及时治疗,易导致老年性痴呆和脑梗死的发生。这些将导致功能性致残,生存质量下降,认知功能障碍甚至危及生命。基于此,对本病进行有效的防治尤显重要。
冠状动脉支架内再狭窄的研究进展

随着科学技术的发展和人民生活水平的提高,经皮冠状动脉介入治疗(PCI)已成为治疗冠状动脉粥样硬化性心脏病(简称冠心病)的主要手段。然而,PCI治疗面临着支架内再狭窄的巨大挑战。支架内再狭窄(ISR)通常指经皮冠状动脉介入术后,随访时冠状动脉造影显示其血管内径再次狭窄≥50%。在药物洗脱支架问世之前,ISR的发生率占PCI的20%~40%,在药物支架应用后,仍有5%~10%的再狭窄率。支架内再狭窄已成为影响患者预后的主要因素之一。现将近年来冠状动脉支架内再狭窄的研究进展作一综述。
牙科畏惧症音乐疗法的研究进展

直接或间接不良的口腔就诊经历、医源性因素、性格因素、诊疗环境、个体认知能力等都是牙科畏惧症的病因,主要表现为烦躁不安、面色苍白、心悸、出汗、脉搏加快、血压升高、高声叫喊,甚至躲避或拒绝口腔治疗。牙科畏惧症降低了患者早期就诊率和治疗效果,恶化医患关系甚至可能产生严重的并发症。本文就牙科畏惧症音乐疗法的研究进展做一综述。
进展性脑卒中危险因素及疗效分析

进展性脑卒中(SIP)约占脑梗死20%~40%。由于病情呈进展性恶化,且发病机制复杂,治疗困难,致残率和致死率均较非SIP患者高,本文探讨SIP发生的危险因素、临床特点及治疗效果。
不同养老模式下老年人日常生活信息查询行为对比

目的对比分析不同养老模式下老年人日常生活信息查询行为特征和信息查询能力。方法采用分层抽样和整群抽样相结合的方法,对全国3 568名60岁以上家庭、社区、机构三种不同养老模式下常住老人进行日常生活信息查询行为调查并测定其信息查询行能力。结果老年人日常生活信息查询行为平均得分为(60.26±13.299),3种不同养老模式下老年人的日常生活信息查询行为有差异(P<0.01),社区养老模式下信息查询分值最高,家庭养老次之,机构养老最低。结论提高老年人的总体信息查询能力,应增强社区养老模式的发展,同时,改善养老机构的生活环境信息查询设施,提高其服务质量,完善其养老功能。
运动促进甘丙肽分泌对大鼠骨骼肌细胞胰岛素敏感性的影响

目的探查运动导致的甘丙肽(GAL)分泌增加,能否提高大鼠骨骼肌细胞胰岛素敏感性。方法大鼠分4组:安静对照组及运动对照组均注射生理盐水,安静用药组及运动用药组注射GAL受体拮抗剂M35。两运动组鼠游泳60 min/d,计14 d。用正糖钳了解胰岛素敏感性,测血清GAL和骨骼肌细胞葡萄糖转运蛋白(GLUT)4浓度及GLUT4 mRNA表达水平。结果两用药组GLUT4 mRNA表达水平、骨骼肌细胞内外膜GLUT4含量和正糖钳实验的葡萄糖输注速率比相应对照组均有显著下降,骨骼肌细胞外膜与细胞总膜GLUT4含量比也下降。而两运动组上述指标及GAL浓度比相应安静组均有显著增加。结论运动诱导GAL浓度增高,可通过增加骨骼肌细胞GLUT4浓度和促进GLUT4向细胞外膜转运而提高胰岛素敏感性。
不同强度有氧运动对动脉粥样硬化大鼠血浆ET-1、NO浓度的影响

目的观察有氧运动对动脉粥样硬化(AS)模型大鼠血浆中内皮素(ET)-1、一氧化氮(NO)浓度的影响。方法①将100只健康纯种雄性Wistar大鼠随机分配五组,对照组(NC组)、高脂组(AS组)、每日运动1 h组(S1.0组)、1.5 h组(S1.5组)、2 h组(S2.0组)。除NC组外,每天喂高脂饲料,游泳共8 w。②光镜下观察各组主动脉弓、大动脉及血管内皮组织形态学改变、放射免疫法检测各组血浆EF-1水平、间接测量法检测各组血浆中NO水平。③采用独立样本T检验法进行组间比较。结果光镜下观察发现运动对AS模型大鼠内皮损伤及AS斑块形成具有抑制作用;不同强度的有氧运动均能够降低血浆中ET-1浓度的同时,升高NO浓度(P<0.05)。结论不同强度有氧运动对AS的内皮损伤、血管内分泌功能方面均有影响。
养寿丹对 AD大鼠学习记忆能力及NGF、TrkA蛋白表达的影响

目的探讨养寿丹对阿尔茨海默病(AD)模型大鼠学习记忆能力及神经生长因子(NGF)、酪氨酸激酶A(TrkA)蛋白表达的影响。方法采用脑基底核内立体定向联合注射β-淀粉样蛋白酶(Aβ_(1~40))和兴奋性氨基酸注射建立AD动物模型,采用Morris水迷宫测试大鼠寻找平台所需时间(潜伏期)和通过原平台次数。采用免疫组织化学染色和计算机图像分析技术测定海马区NGF、TrkA蛋白表达。结果Morris水迷宫实验显示,模型组大鼠在定位航行试验中寻找平台的平均逃避潜伏期明显延长,空间探索试验中跨过原平台位置的次数明显减少;养寿丹组平均逃避潜伏期明显缩短,跨过原平台位置的次数明显增加(均P<0.05)。免疫组织化学染色结果表明:与空白对照组比较,模型组NGF、TrkA蛋白表达显著降低(P<0.05);与模型组比较,假手术对照组、盐酸多奈哌齐组、养寿丹组NGF、TrkA蛋白表达显著升高(P<0.05)。结论养寿丹对AD大鼠的学习记忆障碍具有改善作用,其机制可能与养寿丹增加海马组织NGF、TrkA蛋白的表达有关。
临床使用内植入式给药装置(port)的研讨

鞘内植入式给药装置(port)是一种完全埋置在体内的输液系统,用于持续或反复蛛网膜下腔输注药物,也可用于硬膜外腔持续或反复注药。近年来随着在重度疼痛治疗中蛛网膜下腔输注镇痛应用的增多,该装置得到了广泛的应用,但缺乏相应的应用指导,为此江苏省疼痛学会组织有关专家对该项技术的应用做了多次专题讨论。
Similarity Solutions of Marangoni Convection Boundary Layer Flow with Gravity and External Pressure

This study is focused on a steady dissipative layer, which is generated by Marangoni convection flow over the surface resulted from an imposed temperature gradient, coupled with buoyancy effects due to gravity and external pressure. A model is proposed with Marangoni condition in the boundary conditions at the interface. The similarity equations are determined and approximate analytical solutions are obtained by an efficient transformation, asymptotic expansion and Pade approximant technique. For the cases that buoyancy force is favorable or unfavorable to Marangoni flow, the features of flow and temperature fields are investigated in terms of Marangoni mixed convection parameter and Prantl number.
Support Effects on Thiophene Hydrodesulfurization over Co-Mo-Ni/Al_2O_3 and Co-Mo-Ni/TiO_2-Al_2O_3 Catalysts

Hierarchically macro-/mesoporous structured Al_2O_3 and TiO_2-Al_2O_3 materials were used as supports to prepare novel Co-Mo-Ni hydrodesulfurization (HDS) catalysts. A commercial Co-Mo-Ni/Al_2O_3 catalyst without macroporous channels was taken as a reference. The catalysts were characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), energy-dispersive spectrometry (EDS), N_2 adsorption-desorption, X-ray diffraction (XRD), and temperature programmed reduction (TPR). The apparent activities of the hierarchically porous catalysts for thiophene HDS were superior to those of the commercial catalyst, which was mainly ascribed to the diffusion-enhanced effect of the hierarchically bimodal pore structure. The addition of titania to alumina in the support helped to weaken the interaction between the active phase and the support, and as a result, the novel Co-Mo-Ni/TiO_2-Al_2O_3 catalyst with a low titania loading (28%, by mass) in the support exhibited high HDS activities, even without presulfiding treatment. However, the catalyst with a high titania loading (61%, by mass) showed much lower activities, which was mostly caused by its low surface area and pore volume as well as the non-uniform distribution of titania and alumina. The kinetic analysis further demonstrated the support effects on HDS activities of the catalysts.
四维CT联合呼吸门控技术在非小细胞肺癌放疗中的剂量学研究

在肺癌患者中,呼吸运动是引起靶区运动的重要原因,也是放疗中最大的不确定性因素之一。笔者通过图像软件将呼气末3个连续时相CT进行MIP转换,并将勾画出的靶区与常规IMRT计划靶区进行对比,结果显示PTV_(3D)较PTV_(EOE)增加了(72.82 ±48.65) cm~3,增加的部分占PTV_(3D)的百分比为(20 ±9)%。Underberg等的研究发现基于呼气末3个连续时相门控计划得到的PTV_(gating)体积占常规放疗计划PTV_(10mm)体积的(33. 3 ± 9. 6) %,靶区体积得到了明显缩小。Vlachaki等应用4DCT联合呼吸门控技术对10例胸部恶性肿瘤患者进行研究,发现应用呼吸门控技术制定放疗计划的PTV平均为292. 68 cm~3,而没有应用呼吸门控技术制定的放疗计划PTV平均为575. 17 cm~3。从该研究结果可知,非门控计划PTV几乎为门控计划的2倍,说明门控计划较非门控计划在缩小靶区体积方面具有明显优势。本研究与以上2个研究结果类似,说明应用门控技术可以显著缩小PTV。另外,本研究中除双肺V_5两者相似外,其余均为呼吸门控IMRT计划较常规IMRT计划下降。从对肺保护来看,呼吸门控IMRT计划较常规IMRT计划更有优势。Vlachaki等应用4DCT联合呼吸门控技术对10例胸部恶性肿瘤患者进行研究,结果发现在呼吸门控放疗计划比非门控计划的肺V_(20)、V_(10)显著减少(分别为26. 26%、30. 96%比34. 82%、40. 16%),MLD也显著减少(14. 27 Gy比19. 5 Gy),因此认为4DCT呼吸门控技术显著减少正常组织受照剂量。Underberg等研究发现门控计划中80% PTV处方剂量等剂量线包绕的正常组织体积占常规放疗计划的(39.1 ± 11.5)%。门控计划中正常组织受照体积较常规放疗计划出现了明显下降,显示了门控计划在保护正常组织方面的优势。
Recent Research Progress in λ-Tunable WDM/TDM-PON

This paper describes the current research status of the λ-tunable Wavelength-Division Multiplexing/Time-Division-Multiplexing-Passive Optical Network(WDM/TDM-PON). This optical access system realizes new cost-effective operations from the network operator′s point of view. The main feature of the proposed system is that it aggressively exploits wavelength tunability. We classify the system configurations and applications. Then, we describe key technologies, namely newly developed λ-tuning burst-mode transceivers and a widely applicable Dynamic Wavelength and Bandwith Allocation(DWBA) algorithm. Finally, we summarize our research and discuss several issues related to the λ-tunable Wavelength-Division Multiplexing/Time-Division-Multiplexing-Passive Optical Network(WDM/TDM-PON).
Performance of Dual-throat Supersonic Separation Device with Porous Wall Structure

In this paper, a dual-throat supersonic separation device with porous wall has been proposed to solve the starting problem of supersonic separator, and the feasibility of the proposed device has been tested numerically and experimentally. Its flow characteristics have been investigated and the effect of some important parameters including nozzle pressure ratio (R_(NP)), inlet temperature and swirl intensity were examined. In the device, the supersonic flow state and strong centrifugal acceleration of 240000g can be obtained, which are necessary for the condensation and separation of water vapor. The supersonic region in the device enlarged and the shock wave shifted downstream along with the increasing R_(NP). The separation performance was improved with the increasing R_(NP) and the inlet temperature. The best separation performance in this study was obtained with ΔT_d=28 K.
腹间隔室综合征减压装置的研究

高腹腔压力的处理一直非常棘手,静息腹内压(IAP)在0?5 mmHg (1 mmHg=0.133 kPa)之间,它与个人体形、腹部特征、肌肉张力有关。当患者反复或持续腹腔内压力≥12 mmHg时,为腹高压(IAH);当IAP持续≥20 mmHg 并伴有1个以上器官功能不全表现时为腹腔间隔室综合征(ACS)。为此我们专门设计了1种减压装置,当发生了高腹压,安装此装置后,即可以降低腹腔压力,减少IAH引起的并发症,避免进一步发展到ACS状态。本实验旨在观察此装置的减压效果。
乳腺癌患者生存期与术前血清抗核抗体水平的关系

我们采用间接免疫荧光法检测乳腺恶性肿瘤患者术前血清中抗核抗体水平,探讨抗核抗体在乳腺恶性肿瘤患者愈后的临床意义。
结直肠外科实验研究现状与展望

近年来,随着实验研究的进展,结直肠外科医生对大肠癌、炎性肠病(IBD)、结直肠息肉、微创外科等专业领域的认识提升到一个新的阶段。目前,结直肠癌发生的遗传证据逐渐被揭示,遗传不稳定机制得以阐释,表观遗传学研究不断进展,肠癌干细胞的实验依据不断积累;IBD发病相关的遗传及屏障机制逐渐完善,炎症相关大肠癌的认识逐步深入;结直肠息肉的恶变风险及机制日渐得到认识,防治手段得以进步;微创外科技术不断得以推广,在保证治疗效果的同时减少了创伤,提高了患者生活质量。现对相关实验研究进展做一简要回顾与展望。
针吸细胞学诊断痛风2例

穿刺细胞学中的尿酸盐结晶(痛风)需与焦磷酸钙结晶(假性痛风)鉴别:尿酸盐晶体是两段尖头的针形,焦磷酸钙晶体多为块状; 痛风晶体有强烈的折光性,假性痛风晶体显示弱的折光性。两者形态上的区分较易。尿酸盐结晶不溶于乙醇而溶于福尔马林,因此在福尔马林固定的组织切片上,只能看到白色的无定型区域。目前,细胞涂片多为95%的乙醇固定,因此在观察尿酸盐结晶形态上更具优势。
腮腺局灶性腺瘤样嗜酸细胞增生1例

鉴别诊断: (1)嗜酸细胞腺瘤,圆形、膨胀性单个性结节,有完整包膜,结节生长方式与小叶无关,嗜酸细胞无异型。 (2)嗜酸细胞腺癌,是一种高级别癌,癌细胞核不典型性显著,核分裂易见,呈浸润性生长,区域或远处转移可达60%。局灶性腺瘤样嗜酸细胞增生治疗首选局部手术切除,可治愈; 少数可复发或发展为嗜酸细胞腺瘤,但罕见死亡病例。本例患者肿瘤手术切除后随访10个月,无复发。
双拼对照法在免疫组织化学染色中应用

免疫组化技术是现代病理诊断领域中一项不可缺少的研究与诊断手段,尤其在临床病理诊断中发挥着极其重要的作用,在免疫组化实验中,各实验室会选择不同的检测系统,免疫组化染色的操作方法亦不尽相同。如何在降低成本、保证质量、提高效率的前提下采用更为有效的方法? 作者现采用双拼对照法进行染色,效果较好。所谓双拼对照法,就是把两种病变组织合并到一张玻片上,在完全相同的条件下,进行同一抗体的免疫组化染色,由于实验的内、外部条件完全相同,结果更具有对比性和可靠性,现介绍如下。
合并缺血性左心室功能不全的冠心病患者的OPCAB治疗

目前,冠状动脉旁路移植(CABG)是大多数缺血性左心室功能不全患者的主要治疗手段。虽然体外循环和心肌保护技术日趋完善,其引起的全身炎性反应和心肌缺血再灌注损伤是否影响患者预后仍存争议,非体外循环冠状动脉旁路移植(off-pump coronary artery bypa
何必尽言利?

每个人(当然包括了每个企业家)都有良知与道德,每个企业只有担负起了自己应有的社会责任的同时,让企业不断地发展壮大,不断地赚到合理合法的利润,这才是功在当代,利在千秋的伟业!这样的利,才会让人赚得问心无愧!
松材线虫病早期诊断技术研究评述

早期诊断技术的应用是对松材线虫病这一重大森林生物灾害进行监测预警,进而防控该病害的重要举措。本文从发病症状、病原鉴定、化学生化、媒介昆虫、光谱学、电学、早期检测管等方面对目前松材线虫病早期诊断技术研究进展进行了总结评价,以期对未来更为简便、快速、准确的早期诊断方法的研究提供理论参考。
Tensile Stiffness Analysis on Ocean Dynamic Power Umbilical

Tensile stiffness of ocean dynamic power umbilical is an important design parameter for functional implementation and structural safety. A column with radial stiffness which is wound by helical steel wires is constructed to predict the tensile stiffness value of umbilicals in the paper. The relationship between the tension and axial deformation is expressed analytically so the radial contraction of the column is achieved in the relationship by use of a simple finite element method. With an agreement between the theoretical prediction and the tension test results, the method is proved to be simple and efficient for the estimation of tensile stiffness of the ocean dynamic power umbilical.
Influence of Catalyst Residues on Thermo-oxidative Aging and Thermal Stability of Poly(butene-1)

Isotactic poly(butene-1) (iPB) with spherical morphology was synthesized successfully with bulk precipitation polymerization without post-treatment of the products. The bulk precipitation polymerization process made it possible for iPB to be used as general plastic due to the acceptable decreased cost compared with the solution polymerization process. The influence of catalyst residues on the aging and thermal stability of iPB synthesized by bulk precipitation polymerization method was investigated by gel permeation chromatography, mechanical performance testing, thermogravimetric analysis and infrared spectroscopic analysis. Commercial iPB and the lab-made iPB with varied catalyst residue contents were studied. The results demonstrated that the catalyst residues played an important role in the aging process of the iPB. A possible mechanism of aging promotion by catalyst residues was proposed.
Factors determining the average body size of geographically separated Arctodiaptomus salinus (Daday, 1885) populations

Arctodiaptomus salinus inhabits water bodies across Eurasia and North Africa. Based on our own data and that from the literature, we analyzed the influences of several factors on the intra- and inter-population variability of this species. A strong negative linear correlation between temperature and average body size in the Crimean and African populations was found, in which the parameters might be influenced by salinity. Meanwhile, a significant negative correlation between female body size and the altitude of habitats was found by comparing body size in populations from different regions. Individuals from environments with highly varying abiotic parameters, e.g. temporary reservoirs, had a larger body size than individuals from permanent water bodies. The changes in average body mass in populations were at 11.4 times, whereas, those in individual metabolic activities were at 6.2 times. Moreover, two size groups of A. salinus in the Crimean and the Siberian lakes were observed. The ratio of female length to male length fluctuated between 1.02 and 1.30. The average size of A. salinus in populations and its variations were determined by both genetic and environmental factors. However, the parities of these factors were unequal in either spatial or temporal scales.
Effects of hydroperiod duration on developmental plasticity in tiger frog (Hoplobatrachus chinensis) tadpoles

While developmental plasticity can facilitate evolutionary diversification of organisms, the effects of water levels as an environmental pressure on tiger frogs remains unclear. This study clarifies the relationship by studying the responses of tiger frog (Hoplobatrachus chinensis) tadpoles to simulated hydroperiods (i.e., constant low water levels, constant high water levels, increasing water levels, decreasing water levels, rapid changes in water levels and gradual fluctuations in water levels) in a laboratory setting. ANOVA analysis showed that none of the water level treatments had any significant effect on the total length, body mass, or developmental stages of H. chinensis tadpoles half way through development (11 days old). Tadpoles raised in rapidly fluctuating water levels had protracted metamorphosis, whereas tadpoles raised under low and gradually fluctuating water levels had shortened metamorphosis. None of the water level treatments had a significant effect on the snout-vent length (SVL) or body mass of H. chinensis tadpoles at Gosner stage 42, or on the body mass of tadpoles at Gosner stage 45. However, the tadpoles raised in high levels and rapidly fluctuating water levels, significantly larger SVL at Gosner stage 45, while ones under gradually fluctuating water levels had smaller SVL than the other groups. Time to metamorphosis was positively correlated with body size (SVL) at metamorphosis in H. chinensis tadpoles. H. chinensis tadpoles under constant low water level had the highest mortality rate among all the treatments (G-test). Moreover, ANOVA and ACNOVA (with body length as the covariate) indicated that water levels had no significant effect on either the morphology (i.e. head length, head width, forelimb length, hindlimb length and body width) or the jumping ability of juvenile H. chinensis. These results suggest that the observed accelerated metamorphosis and high mortality of H. chinensis tadpoles under decreasing water level treatment was driven by density-induced physical interactions among increasing conspecifics.
Inter-annual variation of streamflow, precipitation and evaporation in a small humid watershed (Chengcun Basin, China)

For sustainable water resource management, it is important to determine the relationship between streamflow and other variables that influence availability of water resources. However, many catchments do not have sufficient data to allow for a more detailed study of these relationships. We faced a similar challenge in the Chengcun Basin (limited historical data: from 1986–1999); and therefore we used a new approach to overcome this. We found that, using nonparametric trend methods in conjunction with the climate elasticity analyses and the 2D visualization of hydrologic data, it is possible to assess the relationships between streamflow and other hydro-climatic variables. In the past, streamflow trends in the basin were more correlated with precipitation than with potential evapotranspiration (PET). In addition, there is a gradual shift in the hydrological regime of the catchment, which may affect the occurrence of available water resources and activities that depend on them. In addition, based on our climate sensitivity analyses, the streamflow is dependent and more sensitive to variations in precipitation than to PET (δQ=0.79δP+0.42δE; precipitation elasticity, ε_P =1.32; PET elasticity, ε_E =-2.10). Therefore pending more detailed studies, the use of our approach will provide a rapid means to assess the variation of water resources (streamflow) in a watershed. In the future, we hope to carry out related research in other watersheds and also perform a more detailed studies to improve upon the results of this study.
Association of triacylglyceride content and transcript abundance of genes involving in lipid synthesis of nitrogen deficient Phaeodactylum tricornutum

Phaeodactylum tricornutum is a diatom that is rich in lipids. Recently, it has received much attention as a feedstock for biodiesel production. Nitrogen deficiency is widely known to increase the content of neutral lipids (mainly triacylglycerides, or TAGs) of microalgae, including P. tricornutum, but the mechanism is unclear. In this study, we deciphered the correlations between TAG content and nine key enzymatic genes involved in lipid synthesis in P. tricornutum. After being cultured under nitrogen-free conditions for 0, 4, 24, 48, 72, 120, and 168 h, the TAG contents of P. tricornutum cells were assayed and the transcript abundances of the target genes were monitored by quantitative real-time PCR. The results show that the abundances of four target gene transcripts (LACS3, G3PDH2, G3PDH3, and G3PDH5) were positively correlated with TAG content, indicating that these genes may be involved in TAG synthesis in P. tricornutum. The findings improve our understanding of the metabolic network and regulation of lipid synthesis and will guide the future genetic improvement of the TAG content of P. tricornutum.
Seasonal changes in the demersal nekton community off the Changjiang River estuary

The diversity, community structure and seasonal variation in demersal nekton off the Changjiang (Yangtze) River estuary was evaluated using monthly trawl survey data, collected between December 2008 and November 2009. A total of 95 species (56 teleosts, 11 cephalopods, and 28 decapod crustaceans) from 69 genera, 49 families and 15 orders were collected. These species could be classified into six groups on the basis of temporal distribution patterns. The resident crab Ovalipes punctatus dominated the community, both in number and biomass. A clear seasonal succession was observed in the species composition. Cluster analysis revealed three primary seasonal groups corresponding to the samples collected in winter-spring, late spring-summer and late summer-autumn. The highest biomass and lowest diversity were observed in summer, while the lowest biomass and highest diversity in winter. The abundance-biomass comparison curves and community composition suggested that the investigated community was moderately disturbed. The results suggest that reduction in fishing pressure and in the degree of seasonal hypoxia are essential for sustainable resource management off the Changjiang River estuary.
Performance of the (BMAP_1, BMAP_2)/(PH_1, PH_2)/N Retrial Queueing System with Finite Buffer

This paper consider the (BMAP_1, BMAP_2)/(PH_1, PH_2)/N retrial queue with finite-position buffer. The behavior of the system is described in terms of continuous time multi-dimensional Markov chain. Arriving type I calls find all servers busy and join the buffer, if the positions of the buffer are insufficient, they can go to orbit. Arriving type II calls find all servers busy and join the orbit directly. Each server can provide two types heterogeneous services with Phase-type (PH) time distribution to every arriving call (including types I and II calls), arriving calls have an option to choose either type of services. The model is quite general enough to cover most of the systems in communication networks. We derive the ergodicity condition, the stationary distribution and the main performance characteristics of the system. The effects of various parameters on the system performance measures are illustrated numerically.
Global Random Attractors for the Stochastic Dissipative Zakharov Equations

The stochastic dissipative Zakharov equations with white noise are mainly investigated. The global random attractors endowed with usual topology for the stochastic dissipative Zakharov equations are obtained in the sense of usual norm. The method is to transform the stochastic equations into the corresponding partial differential equations with random coefficients by Ornstein-Uhlenbeck process. The crucial compactness of the global random attractors will be obtained by decomposition of solutions.
先天性鱼鳞病共患激素抵抗型肾病综合征2例

目的通过对先天性鱼鳞病共患激素抵抗型肾病综合征(NS)患儿临床表现的分析,认识原发性鱼鳞病并肾脏损害患儿的临床特点。方法回顾性分析患儿临床表现、肾脏病理及治疗经过,并检索相关文献,进一步分析思考鱼鳞病并肾脏损害的机制。结果2例患儿,男性和女性各1例,年龄分别为12岁和10岁,肾脏病变病史均为4个月。临床均表现为生后即出现鱼鳞病表现,原发激素抵抗型NS,行肾脏病理检查均提示为不典型膜性肾病。此外还具有以下共同特征:先天性鱼鳞病,轻到中度智力障碍及生长发育落后,考虑鱼鳞病侏儒智能障碍综合征可能。结论1.原发鱼鳞病是导致肾脏病变的少见原因之一,两者之间具有联系。2.伴有原发鱼鳞病的NS表现的患儿多对激素不敏感。3.肾脏病理可以表现为不典型膜性肾病。
Effect of Electronic Polarization to Human α-Thrombin

The polarized protein-specific charges(PPC)of human α-thrombin(thrombin)and its inhibitor(L86)are made possible by employing the recently developed molecular fractionation with conjugate caps approach incorporated the Poisson–Boltzmann model.Molecular dynamics(MD)simulations of thrombin have been carried out to investigate the dynamics and stability of the thrombin-inhibitor using PPC and AMBER charges respectively.Detailed analysis and comparison of MD results show that the PPC can correctly describe the polarized state of the thrombin and L86.Especially, the root-mean-square deviation of backbone atoms and the hydrogen bonds using PPC are more stable than the AMBER charge.The present results indicate that protein polarization plays critical roles in maintaining the compact structure of thrombin.
Crystallization Kinetics Study on Magnetron-Sputtered Amorphous TiAl Alloy Thin Films

Crystallization kinetics of magnetron-sputtered amorphous TiAl alloy thin films is investigated by differential scanning calorimetry through isothermal analysis and non-isothermal analysis.In non-isothermal analysis, the Kissinger method and the Ozawa method are used to calculate the apparent activation energy and local activation energy, respectively, in the crystallization processes of amorphous TiAl thin films.Furthermore, the crystallization mechanism is discussed from the investigation of the Avrami exponent by isothermal analysis.In addition, x-ray diffraction is utilized to reveal the grain orientation and evolution during the crystallization of TiAl thin films.