mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Spatiotemporal change of ecological footprint and sustainability analysis for Yangtze Delta Region

In the urbanizing world,the Yangtze Delta Region(YDR)as one of the most developed regions in China,has drawn a lot of the world’s attention for the remarkable economic development achieved in the past decades.Nevertheless,the rapid economic development was certain to be accompanied by unprecedented consumption and loss of natural resources.Therefore,the analysis of the ecological situation and driving factors of environmental impact was of great significance to serve the local sustainable development decision-making and build a harmonious society.In this paper,the ecological footprint(EF)was taken as the index of the ecological environmental impact.With the help of Geographic Information System(GIS),we studied the spatiotemporal change of ecological footprint at two scales(region and city)and assessed urban sustainable development ability in YDR.Then we discussed the driving factors that affected the change of ecological footprint by the Stochastic Impacts by Regression on Population,Affluence,and Technology(STIRPAT)model.The results showed that increasing trends of regional ecological footprint during 1998-2008(1.70-2.53 ha/cap)were accompanied by decreasing ecological capacity(0.31-0.25 ha/cap)but expanding ecological deficit(1.39-2.28 ha/cap).The distribution pattern of ecological footprint and the degree of sustainable development varied distinctly from city to city in YDR.In 2008,the highest values of ecological footprint(3.85 ha/cap)and the lowest one of sustainable development index(SDI=1)in YDR were both presented in Shanghai.GDP per capita(A)was the most dominant driving force of EF and the classical EKC hypothesis did not exist between A and EF in 1998-2008.Consequently,increasing in ecological supply and reducing in human demand due to technological advances or other factors were one of the most effective ways to promote sustainable development in YDR.Moreover,importance should be attached to change our definition and measurement of prosperity and success.
Tropical cyclone hazards analysis based on tropical cyclone potential impact index

Tropical cyclone,a high energy destructive meteorological system with heavy rainfall and gale triggered massive landslides and windstorms,poses a significant threat to coastal areas.In this paper we have developed a Tropical Cyclone Potential Impact Index(TCPI)based on the air mass trajectories,disaster information,intensity,duration,and frequency of tropical cyclones.We analyzed the spatial pattern and interannual variation of the TCPI over the period 1949-2009,and taking the Super Typhoon Saomai as an example have examined the relationship between the TCPI and direct economic losses,total rainfall,and maximum wind speed.The results reveal that China's TCPI appears to be a weak decreasing trend over the period,which is not significant overall,but significant in some periods.Over the past 20 years,the TCPI decreased in the southern China coastal provinces of Hainan,Guangdong and Guangxi,while it increased in the southeastern coastal provinces of Zhejiang,Fujian and Taiwan.The highest values of TCPI are mainly observed in Taiwan,Hainan,the coastal areas of Guangdong and Fujian and Zhejiang’s southern coast.The TCPI has a good correlation(P=0.01)with direct economic loss,rainfall,and maximum wind speed.
油棕新品种苗期农艺性状分析

调查了RYL31、RYL32、RYL33、RYL34、RYL35、RYL36、RYL37、RYL38、RYL39、RYL40等10个油棕新引进品种的苗期农艺性状,包括苗高、叶片总数、冠幅、叶长、叶宽、叶厚,通过SPSS13.0软件分析比较,结果表明,RYL39和RYL40苗期各项指标值相对较高,表现出较好的的生长状态。研究结果为下一步继续深化研究油棕新品种的抗逆性,筛选最佳品种进行北移推广提供了初步的依据和参考
植物多糖对多种肿瘤细胞抑制作用的研究进展

多糖生物学是生命科学的新前沿,植物多糖的抗肿瘤作用受到了广泛的重视,在临床也获得了有效应用。对植物多糖对肺癌细胞系、肝癌细胞系、胃癌细胞系、宫颈癌细胞系、S180肉瘤细胞以及其他肿瘤细胞的抑制作用的研究现状进行综述,以期为植物多糖在抗肿瘤方面的应用奠定基础
广东省水稻主栽品种及其发展演变趋势

介绍和剖析了广东水稻主栽品种及其发展演变趋势。超级稻合美占、五优308等主栽品种呈现快速推广种植的发展趋势,主栽品种的推广力度在不断加大。提出了加强广东省主栽品种选育和推广的对策建议,指出把水稻农业主导品种推广培育成主栽品种,将对广东粮食增产有较大推动作用
农村养老保障模式存在的困境分析

受二元保障制度的影响,农村社会保障供给严重不足,随着农村老龄化日益严重,养老保障问题更加凸显。传统的农村养老保障模式面临着诸多困境,分析造成困境的原因,结合农村养老的新需求,探索有中国特色“以家庭养老保障为基础,社区养老服务为核心,社会养老支持为主体”的养老保障体系
15个枣树品种耐盐性研究

从全国主要枣产区引种15个枣(Ziziphus jujube Mill.)品种以及同属不同种的酸枣(Ziziphus spinosus Hu)和毛叶枣 (Zizyphus mauritiana Lam.),以在土壤超高含盐量(2.75%NaCl)胁迫下全生长期栽培的成活率及不同阶段的保存率为鉴定指标,对它们的耐盐性进行了比较。结果表明:枣北方生态型耐盐性普遍显著强于南方生态型,毛叶枣耐盐性最低,酸枣耐盐性强;在枣北方生态型中,西部地区主要栽培品种耐盐性明显强于中、东部地区的主要栽培品种;在中、东部地区主要栽培品种中,金丝小枣、大瓜枣、灰枣表现出优异的耐盐性,著名优良鲜食枣品种冬枣的耐盐性最弱,其余枣品种耐盐性一般至良好;在枣南方生态型中,泗洪大枣耐盐性相对较强,南京冷枣在整个参试枣品种中耐盐性最弱。砧木对枣苗的耐盐性有重要影响。小枣的耐盐性普遍强于大枣
基于“双喜”品牌需求的基地单元烤烟品种试验与选定

为筛选“双喜”品牌需求的南雄基地单元烤烟品种,在南雄黄坑进行小区试验和生产试验。结果表明,NX232、粤烟97长势较强,叶片较大,经济性状、抗病性较好,内在质量中等至较好;K326田间长相一般,长势中等,抗病性较好,经济性状稍差,烟叶内在质量较好;K326LF、KRK26品种存在明显的缺陷,不适合大面积推广
山东省失地农民权益保护问题研究

运用实证研究的方法，对山东省土地流转过程中农民权益状况进行了调查。调查显示，山东省农民普遍存在征地费用过低，失地农民再就业困难重重，土地流转透明度不高，土地补偿方式单一等权益受损的现象。为此，进一步分析了农民权益受损的两方面原因———自身的局限性和外界环境的制约，并提出了尊重和保护农民的民主权利、流转后节约的土地产权归农民所有等一系列保护农民权益的政策和措施
河北省农村居民食物消费结构影响因素的实证分析

影响河北居民食物消费结构变化的因素众多。运用典型相关分析方法进行定量分析，得出各个影响因素对食品消费结构作用的大小，找出消费变量与其影响因素的相关性，从而确定各个影响因素的作用，最后从影响居民消费结构的影响因素来看，人均纯收入的载荷系数最大、影响最大，食品工业价格指数等次之。根据分析结果提出对策建议，以期为河北改善居民消费水平提供参考
中国征地补偿机制中存在的问题及对策

由于当前征地补偿机制存在的不足，失地农民的生活状况急剧下降。失地农民补偿问题引起了政府和社会的高度重视，成为社会各界关注的热点问题。对失地农民补偿现状进行了分析，指出征地补偿机制所存在的弊端、并提出改进补偿机制的对策建议
广东低碳农业的发展现状与对策

随着全球气候的变化，低碳经济成为未来经济发展的主导方向，低碳农业成为新的经济增长点。分析了广东发展低碳农业的现有优势、存在的问题，并提出了改革和完善广东低碳农业发展的对策
湛江地区荔枝蒂蛀虫发生特点及防治措施

荔枝蒂蛀虫是荔枝、龙眼的主要蛀果害虫。该虫在湛江地区具有发生时间早、主害代多、危害逐年加重等特点，多数果园在防治过程中采取的农业措施不足，偏重化学防治且措施不当，造成防治效果较差。通过防治实践，总结了一些有效的防治措施
桂中地区常规优质稻主栽品种比较试验

选择生产上主栽的7个常规优质稻品种油占8号、桂华占、力源占1号、柳沙油占202、柳香占、柳丰香占、佳辐占进行试验，比较各品种的特征特性、产量表现、品质、抗逆性等，旨在为适宜区域选择种植优良品种、提高粮食产量提供参考
蚕沙处理资源化利用研究进展

蚕沙是一种资源,但因难于收集而很少被充分利用。概述了我国蚕沙的资源特性、研究利用情况,比较了我国典型蚕业产区的蚕沙处理现状和做法,以期为蚕沙的综合利用提供参考
翠京元微生物肥在无病毒沙田柚幼树上的应用研究初报

美国翠京元微生物肥是能够促进植物根系健康生长、平衡各营养关系;能充分利用空气中的氮元素和土壤中固有的各种大量及中、微量元素的一种新型肥料。从试验中表现出沙田柚幼树施用翠京元微生物肥抽梢时间能提早3～6 d、梢老熟时间提早2～5 d;抽梢整齐且叶色浓绿、叶片大而厚;冠幅也较对照大
西南桦不同海拔造林试验研究

研究了不同海拔对6年生西南桦树高、胸径、材积生长的影响。结果表明,不同海拔平均树高、平均胸径和平均单株材积从高到低排序均为630 m、750 m、500 m、950 m、400 m、1 250 m、1 450 m,其中海拔630～950 m比400 m和1 250～1 450 m平均树高高18%以上,平均胸径大34%以上,平均单株材积大113%以上。海拔与西南桦速生丰产性和低温雨雪灾害关系密切,在500～ 1 000 m海拔范围Ⅰ类和Ⅱ类地可营造速生丰产林或丰产林,200～500 m和1 000～1 300 m海拔范围可营造一般林,海拔1 300 m以上种植西南桦应谨慎
温室马蹄莲的光合特性研究

用CID-301型便携式光合测定仪,对冬季不同天气条件下温室栽培马蹄莲光合速率Pn及发生影响的生态、生理因子进行了初步的研究,结果表明:晴天和多云天气条件下,一天中净光合速率日变化均为单峰曲线,未出现“午休”现象。由相关性分析可知,影响温室马蹄莲的环境因子主要是光合有效辐射、气温;生理因子主要是胞间CO_2浓度,与净光合速率呈现显著负相关。蒸腾速率与净光合速率的相关性也远大于气孔导度,所以采取措施适当减少马蹄莲的蒸腾作用将会提高其净光合速率
河北省革命老区乡村文化建设探析

乡村文化建设是社会主义新农村建设的重要内容,介绍了河北省革命老区概况,分析了河北省革命老区乡村文化建设的现状及存在问题,提出了河北省革命老区乡村文化建设的发展途径,阐述了河北省革命老区乡村文化建设的对策建议和保障措施
深圳市场蔬菜农药残留监测研究———以2009年为例

分析了2009年深圳各大超市、农贸市场中蔬菜有机磷、有机氯、拟除虫菊酯类农药残留情况,对比2007、2008年的监测情况,分析农药使用的差异,为政府部门决策提供技术支撑。2009年共检测各种蔬菜样品6 820份,采用农药快速检测方法结合气相色谱和气质联用法测定其中24种农药残留。蔬菜农药检出率与超标率分别为4.34%、2.21%,蔬菜农药检出率比2008年下降 0.95%,超标率比2008年下降1.32%,分别比2007年下降0.97%和0.78%。2009年的蔬菜农药残留比2008年有明显下降；引起蔬菜超标的主要原因是有机磷农药残留,菊酯类农药引起的超标情况有所下降,应有针对性地加强监督管理
华桑与桑树栽培种远缘杂交育性研究

用华桑与桑树栽培种进行远缘杂交,结果显示,因远缘杂交类型和组合不同,其受孕率、结实率和可育性上有较大的差异。华桑×桑树栽培种的杂交受孕率38.72%～54.98%,平均受孕率为46.35%；杂交结实率37.86%～52.16%,平均结实率44.95%；杂交可育性10.70%～22.80%,平均可育性16.24%。桑树栽培种×华桑的杂交受孕率28.85%～45.16%,平均受孕率37.05%；杂交结实率 25.31%～41.09%,平均结实率33.16%；杂交可育性5.34%～14.15%,平均可育性10.21%。华桑×桑树栽培种的平均杂交受孕率、杂交结实率和杂交可育性比栽培种×华桑分别提高9.30、11.79、6.03个百分点
基于VAR模型的政策性补贴与中国农业增长分析

运用VAR模型,分析了我国用于农业的政策性补贴与农业经济增长的关系,通过对我国1985—2006的相关数据分析发现:用于农业的政策性补贴与农业生产总值之间存在长期均衡关系;对农业经济增长贡献最大的是自身因素的变化,但是其对自身的贡献率呈现出逐年递减的趋势,而农业政策性补贴对农业经济增长的贡献逐年增加
小型内燃机尾气发电系统设计

利用高效率的热电材料，设计出一套小型内燃机尾气发电系统。通过尾气集热器收集内燃机尾气的余热，利用高效率的半导体温差发电片，将尾气的热能转化为电能。利用散热装置给半导体温差发电片的冷端散热，以增大冷、热端的温差，提高发电效率。发出的电由控制系统控制，先经过充电电路充入中转蓄电池，再经过升压模块升至14 V，给小型内燃机上的蓄电池充电及电气设备供电。经过计算，安装该系统的内燃机如果每天工作6 h，现在中国的小型内燃机按6000万辆计算，那么1 d就可以节省汽油428 000 L
辽宁土壤盐分变异特征及相关性分析

选取辽宁省土样100个，进行水溶性盐变异特征及相关性分析，结果表明:水溶性盐含量规律表现为SO_4~(2-)＞Cl~-＞Ca~(2+)＞Na~+＞Mg~(2+)＞HCO_3~-＞K~+。阳离子主要是Ca~(2+)和Na~+，阴离子主要是SO_4~(2-)和Cl~-。大部分土壤属于重度盐土，少数为盐渍化土和中等盐渍化土。K~+、Mg~(2+)、SO_4~(2-)、Na~+、Cl~-、Ca~(2+)含量变异性较大，水溶性盐总量、HCO_3~-含量变异性中等。水溶性盐总量与Cl~-、K~+和Na~+含量呈显著正相关，水溶性盐总量与SO_4~(2-)、K~+和Ca~(2+)含量呈显著正相关
超临界CO2萃取技术及在植物油脂制备中的应用研究

超临界萃取技术具有提纯过程简单、产率高、对环境友好无污染等特点，在化学反应和分离提纯等领域有着广泛的应用。结合超临界流体的特点及超临界CO_2的优势，综述了其在萃取植物油脂方面的应用研究进展，并对发展趋势进行了展望
营养性缺铁性贫血对6～12岁儿童学习能力的影响

目的探讨6～12岁儿童营养性缺铁性贫血(IDA)对学习能力的影响。方法选取48例6～12岁IDA患儿为IDA组,另选取96例6～12岁健康儿童为健康对照组,分别接受韦氏儿童智力量表第4版(WISC-Ⅳ)测试与文化课测试,进行对比研究。结果IDA组言语理解指数、知觉推理指数、工作记忆指数、加工速度指数、总智商5方面测试成绩明显低于健康对照组儿童,差异均有统计学意义(P_a＜0.01);IDA组重度IDA者在言语理解指数、知觉推理指数、工作记忆指数、加工速度指数、总智商5方面测试成绩均明显低于轻度IDA者,差异均有统计学意义(P_a＜0.01);IDA组语文、数学、英语3门文化课测试成绩优良率均明显低于健康对照组,差异均有统计学意义(P_a＜0.01)。结论IDA对儿童的学习能力有严重影响,其程度与其病情轻重有关
英夫利西在儿童克罗恩病中的应用

英夫利西作为一种针对肿瘤坏死因子的单克隆抗体,在儿童克罗恩病(CD)的治疗中已开始应用。许多大的随机对照研究已经显示其对儿童CD的诱导缓解和维持治疗具有良好的疗效,尤其是生长发育的恢复及降低肠切除术的概率,提高患儿的生活质量。英夫利西的治疗方案包括诱导缓解和维持治疗,前者在第0、2、6周以5 mg·kg~(-1)的剂量静脉滴注,后者在缓解后每8周以相同剂量维持治疗。在治疗过程中要注意调整剂量和用药间隔,以避免失效。严重感染、输液反应、药物性红斑狼疮等不良反应也是重点关注的问题,目前英夫利西是否有致癌的可能性并不清楚,需要长期的随访观察
风力发电中的电力电子与系统技术专辑特邀主编评述

风能作为一种清洁的可再生能源，越来越受到世界各国的重视。其蕴藏量巨大，全球风能资源总量约为2.74×109 MW，其中可利用的风能为2× 107 MW。中国风能储量很大、分布面广，开发利用潜力巨大。[取自正文]
Grid Harmonic and Control Delay Compensation for Three-phase Grid-connected VSIs in Small Wind Turbine Systems

Voltage space vector pulse-width modulation（SVPWM）has been widely applied to control current in threephase voltage source inverters（VSI）.However，as a voltage type modulator，SVPWM has certain drawbacks compared with current type modulators for grid-connected applications.For a grid-connected VSI，the performance of existing current controllers based on SVPWM is compromised by grid harmonics，control delay and system nonlinearities such as switching dead time.Moreover，unlike current type PWM，SVPWM does not inherently have over-current protection.A novel SVPWM-based current controller is proposed for three-phase grid-connected VSIs for small wind turbine applications.To overcome the drawbacks of SVPWM，a grid harmonic compensation method is proposed along with compensation for control delays.Both simulation and experimental results have established excellent steady-state response and fast dynamic response of the current controller.In addition，the DSP-based control system has both improved real-time control performance and fast response for over-current protection.
Current Source Converter Based Wind Energy Conversion Systems

The increase in the installed capacity of wind energy conversion systems（WECS）has triggered the development of more demanding grid codes and additional requirements on performance.In order to meet these requirements the industry trend has shifted to full-scale power converter interfaces in modern multi-megawatt WECS.As consequence，a wide variety of new power converter topologies and WECS configurations have been introduced in recent years.Among them，current source converter（CSC）based configurations have attracted attention due to a series of advantages like:simple structure，grid friendly waveforms，controllable power factor，and reliable grid short-circuit protection.This paper presents the latest developments in CSC interfaces for WECS and related technologies such as modulation methods，control schemes and grid code compatibility.
Quasi-real-time simulation of rotating drum using discrete element method with parallel GPU computing

Real-time simulation of industrial equipment is a huge challenge nowadays.The high performance and fine-grained parallel computing provided by graphics processing units (GPUs)bring us closer to our goals.In this article,an industrial-scale rotating drum is simulated using simplified discrete element method (DEM)without consideration of the tangential components of contact force and particle rotation.A single GPU is used first to simulate a small model system with about 8000 particles in real-time,and the simulation is then scaled up to industrial scale using more than 200 GPUs in a 1 D domain-decomposition parallelization mode.The overall speed is about 1/11 of the real-time.Optimization of the communication part of the parallel GPU codes can speed up the simulation further,indicating that such real-time simulations have not only methodological but also industrial implications in the near future.
The ultimate goal of modeling-Simulation of system and plant performance

Modern production processes in chemical,pharmaceutical and biological industries are characterized by complex process structures,which consist of different apparatuses and process steps.Modeling the entire process requires simulating all units altogether,while taking into account interconnections between them.Nevertheless,in the area of solids processing,there is nowadays an unfilled gap from the side of computer support of process modeling in allowing effective optimization and prediction of the behavior of the whole plant.This paper presents a tool for flowsheet simulation which allows the simulation of the stationary behavior of complex processes dealing with solids and its extension towards dynamic modeling.Also,a new simulation concept is proposed on the basis of the multiscale approach.On the macroscale,flowsheet simulation is performed with the help of the SolidSim system.Parameters for the macromodels in Solid-Sim are predicted by microscale simulation.The models for the two scales are then coupled by inter-scale communication laws.Application of the proposed modeling concept is shown by an example of fluidized bed granulation.
Preparation of NaYF4:Er3+/TiO2 composite and up-conversion luminescence properties under visible light excitation

The up-conversion luminescence composite NaYF4:Er3+/TiO2 is prepared using the sol-gel method.The specimen has good crystallinity and two shapes,i.e.,viereck and round,while the sizes of viereck and round particles are both micron-sized.The TiO2 has an anatase structure,while the NaYF4 has a hexagonal phase,which can be hardly obtained through the common sol-gel method.Due to the big particle size and the high crystallinity of pure NaYF4:Er3+,the composite has a small specific surface area that is less than Degussa P25 TiO2.The NaYF4:Er3+/TiO2 composite shows several emission peaks at 211,237,and 251 nm under the excitation of 388 nm,at 395 nm and 411 nm under the excitation of 500 nm,and at 467,481,492,and 508 nm under the excitation of 570 nm.
Parallel computing of discrete element method on multi-core processors

This paper describes parallel simulation techniques for the discrete element method (DEM)on multi-core processors.Recently,multi-core CPU and GPU processors have attracted much attention in accelerating computer simulations in various fields.We propose a new algorithm for multi-thread parallel computation of DEM,which makes effective use of the available memory and accelerates the computation.This study shows that memory usage is drastically reduced by using this algorithm.To show the practical use of DEM in industry,a large-scale powder system is simulated with a complicated drive unit.We compared the performance of the simulation between the latest GPU and CPU processors with optimized programs for each processor.The results show that the difference in performance is not substantial when using either GPUs or CPUs with a multi-thread parallel algorithm.In addition,DEM algorithm is shown to have high scalability in a multi-thread parallel computation on a CPU.
DEM simulation of influence of parameters on energy and degree of mixing

Powder mixing is being modeled using a simulation based on Newtonian mechanics.Variables under consideration include particle friction and the amplitude,frequency,and direction of shaking.Trajectories for each particle were recorded,and a mixing degree was calculated for each simulation,for which the average energy transferred into the powder system was recorded and compared to the resulting mixing degree.Mixing of particles originally located near the bottom was studied separately,as was the mixing of particles near the surface.This study shows that choosing the proper mixing parameters not only enhances the final result of mixing,but also yields good results with less strain on the material mixed and on the mixing device.
Linking discrete particle simulation to continuum process modelling for granular matter:Theory and application

Two approaches are widely used to describe particle systems:the continuum approach at macroscopic scale and the discrete approach at particle scale.Each has its own advantages and disadvantages in the modelling of particle systems.It is of paramount significance to develop a theory to overcome the disadvantages of the two approaches.Averaging method to link the discrete to continuum approach is a potential technique to develop such a theory.This paper introduces an averaging method,including the theory and its application to the particle flow in a hopper and the particle-fluid flow in an ironmaking blast furnace.
A new kind of nonlinear phenomenon in coupled fractional-order chaotic systems:coexistence of anti-phase and complete synchronization

In this paper,we have found a kind of interesting nonlinear phenomenon-hybrid synchronization in linearly coupled fractional-order chaotic systems.This new synchronization mechanism,i.e.,part of state variables are antiphase synchronized and part completely synchronized,can be achieved using a single linear controller with only one drive variable.Based on the stability theory of the fractional-order system,we investigated the possible existence of this new synchronization mechanism.Moreover,a helpful theorem,serving as a determinant for the gain of the controller,is also presented.Solutions of coupled systems are obtained numerically by an improved Adams-Bashforth-Moulton algorithm.To support our theoretical analysis,simulation results are given.
Phase relations in the ZnO-V2O5-K2O system

The subsolidus phase relations of a ZnO-V2O5-K2O system are investigated by X-ray powder diffraction.There is 1 ternary compound,11 binary compounds and 14 three-phase regions in this system.The phase diagrams of V2O5-K2O with the K2O content ranging from 0 to 71 mol% and pseudo-binary system of ZnO-K2ZnV2O7 are also studied by X-ray powder diffraction and differential thermal analysis methods.
艾滋病合并马尔尼菲青霉病累及咽部一例

艾滋病(acquired immune deficiency syndrome，AIDS)患者由于感染了人类免疫缺陷病毒(human immunodeficiency vrus，HIV)，患者的CD4阳性T淋巴细胞受HIV病毒特异性侵犯，使机体免疫功能严重受损以致低下，导致机体发生各种机会性感染，其中真菌感染相当严重，疾病的表现形式日趋复杂。现报道1例马尔尼菲青霉病(penicilliosis Mameffei，PSM)累及咽部，表现为咽部肿物的艾滋病患者诊治经过。[取自正文]
镶嵌式外固定支架治疗胫骨干骨不连与骨缺损

目的 探讨应用镶嵌式外固定支架治疗胫骨干骨不连与骨缺损的临床疗效。 方法 自 2006年3月至2010年10月收治40例胫骨干骨折术后骨不连及骨缺损患者，男30例，女10例；年龄 19～45岁，平均28．4岁；左侧26例，右侧14例。骨不连按Weber．Czech分类:非感染性骨不连30例，感染性骨不连10例；合并骨缺损或肢体短缩18例，骨缺损或肢体短缩2～10 cm，平均6．1 cm。均采用镶嵌式外固定支架固定治疗。骨不连断端未植骨处理。同期行皮瓣修复者4例，行负压封闭引流二期皮瓣或植皮修复者5例。 结果 36例患者术后获10～48个月(平均15个月)随访，4例失访。所有患者骨不连均获愈合，愈合时间为6～12个月，平均7．8个月。短缩2～3 cm者3例，短缩2 cm以下者4例。4例患者骨折愈合后骨折端在冠状面或矢状面上有成角，成角5°～10°，平均8°。相邻膝、踝关节功能恢复良好。 结论镶嵌式外固定支架治疗胫骨干骨不连及骨缺损方法简单、有效，可早期功能锻炼，感染患者可获一期愈合。
Pharmacokinetics of Quinocetone and Its Major Metabolites in Swine After Intravenous and Oral Administration

The pharmacokinetics of quinocetone and its major metabolites in healthy swine was investigated in this paper.Quinocetone was administered to 8 healthy cross-bread swine intravenously and orally at a dosage of 4 and 40 mg kg-1 body weight respectively in a randomized crossover design test with two-week washout period.A sensitive highperformance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)method was developed for the determination of quinocetone and its metabolite 1-desoxyquinocetone in plasma.Plasma concentration versus time profiles of quinocetone and its metabolite 1-desoxyquinocetone were analyzed by non-compartmental analysis using Winnonlin 5.2 software.Mean maximum concentrations(C_(max))for quinocetone was found to be(0.56±0.13)μg mL-1 at 2.92 h,after oral administration of quinocetone.Mean maximum concentrations(C_(max))for 1-desoxyquinocetone after intravenous or oral administration of quinocetone were(0.0095±0.0012)μg mL-1 at 0.083 h and(0.0067±0.0053)μg mL-1 at 3.08 h.The apparent elimination half-lives(T_(1/2))for quinocetone and its metabolite 1-desoxyquinocetone were(2.24±0.24)and (5.23±0.56)h after intravenous administration of quinocetone and(2.91±0.29)and(11.85±2.89)h after oral administration of quinocetone,respectively.Mean areas under the plasma concentration-time curve(AUC_(0-∞))for quinocetone and 1-desoxyquinocetone were(2.02±0.15)and(0.2±0.002)μg h mL-1 respectively after intravenous administration of quinocetone,and(3.5±0.79)and(0.053±0.03)μg h mL-1 after oral administration of quinocetone,respectively.Quinocetone was rapidly absorbed and metabolized in swine after oral and intravenous administration.The plasma concentration-time curve (AUC_(0-∞))of 1-desoxyquinocetone were much smaller than those of quinocetone,while the elimination half-lives(T_(1/2))were much longer than those of quinocetone after intravenously(i.v.)or oral administration.
The Study on the Effects of Chinese Herbal Mixtures on Growth,Activity of Post-Ruminal Digestive Enzymes and Serum Antioxidant Status of Beef Cattle

Sixteen Limousin×Luxi crossbred beef cattle[(199.4±8.67)kg]were used to evaluate the effects of Chinese herbal mixtures (CHM)on growth,activities of post-ruminal digestive enzymes and serum antioxidant status of beef cattle.Treatments were control(no CHM supplementation)and three formulations of CHM(CHM-A,CHM-B and CHM-C)that were arranged as completely randomized design.The calves were fed in indoor individual feeding barn with total mixed ration for 90 d.The CHM-A,CHM-B,and CHM-C was incorporated into the diet at the level of 20 g kg-1 DM(dry matter)of concentrate.The cattle were weighted at the beginning,at the end and every 15 d between to determine growth rate.Blood sample was taken every 30 d to analyze activities of total superoxide dismutase(T-SOD)and glutathione peroxidase(GSH-PX)and concentration of malondialdehyde(MDA).The cattle were slaughtered at the end of experiment and chymus samples from various section of the post-ruminal digestive tract were collected to analyze enzymes activities.All cattle had similar average daily gain,but cattle supplemented with CHM-A tended faster growth(P=0.08)compared to the control and other CHM treatments.Supplementation of CHM did not affect pH of chymus in any section of the post-ruminal digestive tract.Activities of pepsin,trypsin,chymotrypsin,and lipase in chymus samples were enhanced(P<0.05)to various extents by supplementation of CHM-A,CHM-B,and CHM-C depending on the enzymes and the site of the digestive tract.Amylase activity was increased only by CHM-A and CHM-C from chymus sample collected at the ileum.Supplementation of CHM-A and CHM-B reduced(P<0.05)concentration of MDA,but did not affect GSH-PX activity in the serum of cattle throughout the entire experimental period.Cattle supplemented with CHM-B also had higher(P<0.05)T-SOD activity in the serum at day 30 and 60 as compared with the control and the other two CHM treatments.Chinese herbal mixtures supplemented at the levels of 20 g kg-1 DM of concentrate increased post-ruminal digestive enzymes activity and enhanced serum antioxidant status.Inclusion of CHM-A and CHM-B in the diet may be favourable for ruminant production.