mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
A Hybrid State Estimation Approach for Integrated Heat and Electricity Networks Considering Time-scale Characteristics

State estimation (SE) usually serves as the basic function of the energy management system (EMS).In this paper, the time-scale characteristics of the integrated heat and electricity networks are studied and an SE model is established.Then, a two-stage iterative algorithm is proposed to estimate the time delay of heat power transportation in the pipeline.Meanwhile, to accommodate the measuring resolutions of the integrated network, a hybrid SE approach is developed based on the two-stage iterative algorithm.Results show that, in both steady and dynamic processes, the two-stage estimator has good accuracy and convergence.The hybrid estimator has good performance on tracking the variation of the states in the heating network, even when the available measurements are limited.
Marijuana use and repeated attempted suicide among senior high school students in Ghana: Evidence from the WHO Global School-Based Student Health Survey, 2012

Background The association between substance use including marijuana use and attempted suicide has been well documented. However, little is known about marijuana use and its association with attempted suicide repetition among young people in low-income and middle-income contexts. Aims This analysis was conducted to assess the factors associated with marijuana use and ascertain marijuana use as a determinant of repeated attempted suicide among senior high school (SHS) students in Ghana. Methods Data from the 2012 Global School-Based Student Health Survey in Ghana was used for this study. Modified Poisson, Logistic and Probit models weighted with Mahalanobis distance matching within propensity calliper were employed separately to determine the hypothetical association between marijuana use and repeated attempted suicide. All analysis was performed using Stata 16 and p≤0.05 was deemed statistically significant. Results The prevalence estimates of marijuana use and repeated attempted suicide among SHS students in Ghana were 3.4% (95% CI: 2.3 to 5.1) and 11.5% (95% CI: 9.1 to 14.4), respectively. The prevalence of marijuana use was significantly associated with school grade, smoking exposure, parent smoker, alcohol intake and truancy. Marijuana use was positively associated with repeated attempted suicide among SHS in Ghana (φ correlation=0.23, p<0.001). Repeated attempted suicide among students who use marijuana was approximately threefold and fivefold significant compared with non-marijuana use students, based on the Poisson (adjusted prevalence ratio: 3.02; 95% CI: 1.67 to 5.43, p<0.001)and Logistic (adjusted OR:5.06; 95% CI: 3.19 to 11.64, p<0.001) estimates respectively. Also, the Probit model showed that marijuana use significantly increased the log count of repeated attempted suicide by 95% (aβ: 0.95; 95% CI: 0.49 to 1.41,p<0.001). Conclusion Marijuana use does not only influence the onset of suicidal attempts but also repeated attempted suicide among SHS students in Ghana. Special attention is required for suicide attempters with a history of repeated attempts and current marijuana use among SHS students in Ghana. Early identification of the potential risk and protective factors is recommended to inform school-based interventions. National level structured school-based substance abuse interventions and health promotion programmes would be useful.
Comparison of Different Virtual Inertia Control Methods for Inverter-based Generators

With the rapid development of inverter-based generators (IGs), power grid is faced with critical frequency stability challenges because the existing IGs have no inertia.To equip IGs with inertial response, researchers have proposed several virtual inertia control methods, which can be classified into two categories: virtual synchronous generator (VSG) control and droop control based on rate of change of frequency (ROCOFdroop control).In this paper, the comparison between both virtual inertia control methods is conducted from three perspectives: mathematical model, output characteristic and small-signal stability.State-space models are firstly built to analyze the control mechanism of VSG control and ROCOF-droop control methods.Simulation and eigenvalue analysis are conducted to study the transient responses and oscillation characteristics of both methods, which is helpful to understand the advantages and limitations of existing virtual inertia control methods.Finally, the obtained theoretical results are validated through realtime laboratory (RT-LAB) hardware-in-loop simulation platform.
Role of neutrophil chemoattractant CXCL5 in SARSCoV- 2 infection-induced lung inflammatory innate immune response in an in vivo hACE2 transfection mouse model

Understanding the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and clarifying antiviral immunity in hosts are critical aspects for the development of vaccines and antivirals. Mice are frequently used to generate animal models of infectious diseases due to their convenience and ability to undergo genetic manipulation. However, normal adult mice are not susceptible to SARS-CoV-2. Here, we developed a viral receptor (human angiotensin-converting enzyme 2, hACE2) pulmonary transfection mouse model to establish SARS-CoV-2 infection rapidly in the mouse lung. Based on the model, the virus successfully infected the mouse lung 2 days after transfection. Viral RNA/protein, innate immune cell infiltration, inflammatory cytokine expression, and pathological changes in the infected lungs were observed after infection. Further studies indicated that neutrophils were the first and most abundant leukocytes to infiltrate the infected lungs after viral infection. In addition, using infected CXCL5-knockout mice, chemokine CXCL5 was responsible for neutrophil recruitment. CXCL5 knockout decreased lung inflammation without diminishing viral clearance, suggesting a potential target for controlling pneumonia.
First-principles-aided thermodynamic modeling of transition-metal heterogeneous catalysts: A review

Over the past decade, the first-principles-aided thermodynamic models have become standard theoretical tools in research on structural stability and evolution of transition-metal heterogeneous catalysts under reaction environment. Advances in first-principles-aided thermodynamic models mean it is now possible to enable the operando computational modeling, which provides a deep insight into mechanism behind structural stability and evolution, and paves the way for high-through screening for promising transition-metal heterogeneous catalysts. Here, we briefly review the framework and foundation of first-principles-aided thermodynamic models and highlight its contribution to stability analysis on catalysts and identification of reaction-induced structural evolution of catalyst under reaction environment. The present review is helpful for understanding the ongoing developments of first-principles-aided thermodynamic models, which can be employed to screen high-stability catalysts and predict their structural reconstruction in future rational catalyst design.
Combined limit on the photon mass with nine localized fast radio bursts

A nonzero-mass hypothesis for the photon can produce a frequency-dependent dispersion of light, which results in arrival-time differences of photons with different frequencies originating from a given transient source. Extragalactic fast radio bursts (FRBs), with their low frequency emissions, short time durations, and long propagation distances, are excellent astrophysical probes to constrain the restmass of the photon m. However, the derivation of a limit on m_γ is complicated by the similar frequency dependences of dispersion expected from the plasma and nonzero photon mass effects. If a handful measurements of redshift for FRBs are available, then the different redshift dependences of the plasma and photon mass contributions to the dispersion measure (DM) might be able to break dispersion degeneracy in testing the photon mass. For now, nine FRBs with redshift measurements have been reported, which can turn this idea into reality. Taking into account the DM contributions from both the plasma and a possible photon mass, we use the data on the nine FRBs to derive a combined limit of m_γ ≤ 7.1×10~(-51) kg, or equivalently m_γ ≤ 4.0×10~(-15) eV/c~2 at 68% confidence level, which is essentially as good as or represents a factor of 7 improvement over previous limits obtained by the single FRBs. Additionally, a reasonable estimation for the DM contribution from the host galaxy, DM_(host), can be simultaneously achieved in our analysis. The rapid progress in localizing FRBs will further tighten the constraints on both m_γ and DM_(host).
A facile synthesis of non-aqueous LiPO_2F_2 solution as the electrolyte additive for high performance lithium ion batteries

Constructing a reliable and favorable electrode-electrolyte interface is crucial to utilize the exceptional energy storage capability in commercial lithium-ion batteries. Here, we report a facile synthesis approach for the lithium difluorophosphate (LiPO_2F_2) solution as an effective film-forming additive via direct adding the Li_2CO_3 into LiPF_6 solution at 45℃. Benefiting from the significantly reduced interface resistance (R_(SEI)) and charge transfer impedance (R_(ct)) of both the cathode and anode by adding the prepared LiPO_2F_2 solution into a baseline electrolyte, the cycling performance of the graphite|| LiNi_(0.5)Mn_(0.3)Co_(0.2)O_2 pouch cell is remarkably improved under all-climate condition.
NIR-triggered drug delivery system based on phospholipid coated ordered mesoporous carbon for synergistic chemo-photothermal therapy of cancer cells

Chemo-photothermal treatment is one of the most efficient strategies for cancer therapy. However, traditional drug carriers without near-infrared absorption capacity need to be loaded with materials behaving photothermal properties, as it results in complicated synthesis process, inefficient photothermal effects and hindered NIR-mediated drug release. Herein we report a facile synthesis of a polyethylene glycol (PEG) linked liposome (PEG-liposomes) coated doxorubicin (DOX)-loaded ordered mesoporous carbon (OMC) nanocomponents (PEG-LIP@OMC/DOX) by simply sonicating DOX and OMC in PEG-liposomes suspensions. The as-obtained PEG-LIP@OMC/DOX exhibits a nanoscale size (600± 15 nm), a negative surface potential (-36.70 mV), high drug loading (131.590 mg/g OMC), and excellent photothermal properties. The PEG-LIP@OMC/DOX can deliver loaded DOX to human MCF-7 breast cancer cells (MCF-7) and the cell toxicity viability shows that DOX unloaded PEG-LIP@OMC has no cytotoxicity, confirming the PEG-LIP@OMC itself has excellent biocompatibility. The NIR-triggered release studies demonstrate that this NIR-responsive drug delivery system enables on-demand drug release. Furthermore, cell viability results using human MCF-7 cells demonstrated that the combination of NIR-based hyperthermal therapy and triggered chemotherapy can provide higher therapeutic efficacy than respective monotherapies. With these excellent features, we believe that this phospholipid coating based multifunctional delivery system strategy should promote the application of OMC in nanomedical applications.
A newfluorescent quinoline derivative toward the acid-responsivity in both solution and solid states

In this article, an acid-responsive luminescent material, 1,4-di(quinoline-6-yl)buta-1,3-diyne (DQBD)is designed and synthesized.Upon different pH values, gradual changes of fluorescence colors for DQBD in both solution and solid phases are demonstrated due to the protonation effect.Moreover, such responsive characteristics can also be reversible, suggesting DQBD as a promising fluorescent material with great potential for reusable-and accurate-pH sensors in the future.
Ultrafast O_2 activation by copper oxide for 2,4-dichlorophenol degradation: The size-dependent surface reactivity

This study demonstrated interesting ultrafast activation of molecular O_2 by copper oxide (CuO)particles and very rapid elimination of aqueous 2,4-dichlorophenol (2,4-DCP)within reaction time of 30 s. Electron paramagnetic resonance (EPR)characterization indicated that ·OH,Cu~(3+), ~1O_2 and O_2~(·-)were generated in the CuO/O_2 systems, wherein O_2~(·-)would be the main reactive species responsible for 2,4-DCP degradation. It was further found that the catalytic ability of CuO for O_2 activation was highly size dependent and nano-CuO was far reactive than micro-CuO. H2 temperature-programmed reduction (H2-TPR), X-ray photoelectron spectroscopy (XPS)and vibrating sample magnetometer (VSM)analyses revealed that both the quantity and the reactivity of the surface reaction sites (surface Cu~+ and O_2)could determine the catalytic ability of CuO affecting efficient Cu+-based molecular oxygen activation. Moreover, the O_2 activation ability of CuO would depend on not only the dimension, but also crystalline factors, for example, the exposed facets.
Efficient removal for multiple pollutants via Ag_2O/BiOBr heterojunction: A promoted photocatalytic process by valid electron transfer pathway

Multiple pollutants including pathogenic microorganism contaminations and emerging organic contaminations (EOCs)have shown a growing threat to the environment, especially the natural waters. However, the control and removal of pathogenic microorganism contaminations and EOCs have been greatly limited since limited knowledge of their environmental behaviors. Thus, a novel and efficient photocatalyst Ag_2O/BiOBr heterojunction was synthesized and used for removal of multiple pollutants including Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), tetracycline and acetaminophen under visible light. The results showed that there were valid electron transfer pathways between BiOBr and Ag_2O, the main electron transfer direction was the BiOBr to Ag_2O. Photo-generated electrons were stored in Ag_2O and thus separation efficiency between holes and photo-generated electrons was obviously enhanced. Active oxygen species were highly produced and eventually end up with the high efficiency of removal of multiple pollutants. For Ag_2O/BiOBr with Ag_2O content at 3% (the best performance)under visible light, log decrease of E. coli was 7.16 (removal efficiency was 100%)in 120 min,log decrease of S. aureus was 7.23 (removal efficiency was 100%)in 160 min, C/C_0 of tetracycline was 0.06 in 180 min, C/C_0 of acetaminophen was 0.17 in 180 min. This work could provide a promising candidate in the actual contaminated natural waters for cleaning multiple pollutants.
InP quantum dots on g-C_3N_4 nanosheets to promote molecular oxygen activation under visible light

Largely limited by the high dissociation energy of the O-O bond, the photocatalytic molecular oxygen activation is highly challenged, which restrains the application of photocatalytic oxidation technology for atmospheric pollutants removal. Herein, we design and fabricate the InP QDs/g-C_3N_4 compounds. The introduction of InP QDs promotes the charge transfer within the interface resulting in the effective separation of photo-generated carriers. Furthermore, InP QDs greatly facilitates the activation of molecular oxygen and promote the formation of O_2~(·-)under visible-light illumination. These conclusions are identified by experimental and calculation results. Hence, NO can be combined with the O_2~(·-)to form O-O-N-O intermediate to direct conversion into NO_3~-. As a result, the NO removal ratio of g-C_3N_4 has a onefold increase after InP QDs loaded and the generation of NO_2 is effectively inhibited. This work may provide a strategy to design highly efficient materials for molecular oxygen activation.
以精神障碍为首发表现的中枢神经系统LCH—例报道及文献复习

朗格汉斯细胞组织细胞增生症(LCH)是单核-巨噬系统的一种罕见疾病,可侵犯所有器官,造成局限性或广泛性脏器损害,而中枢神经系统(CNS)-LCH较为少见,以精神障碍为首发表现的CNS-LCH在临床上更为罕见。济宁市精神病防治院伽玛刀治疗科收治了1例以精神障碍为首发表现的CNS-LCH患者,笔者现将其诊治经过报道如下,以增强临床同道对该病的认识。
颅脑损伤合并颌骨骨折行同期手术的临床观察

颅脑损伤合并颌骨骨折的危险程度主要取决于颅脑血肿的程度。临床上对这类伤员的抢救原则按生命、器密、功能的顺序进行。但当颅脑血肿与颌骨骨折同期发生并危及生命时，实施同期手术的必然性和风险性也就同时出现。作者对实施同期手术的11例颅脑损伤合并颌骨骨折病例作回顾性分析，探讨实施同期手术的临床适应证。
DSP与慢速设备接口的实现

介绍了DSP与慢速设备接口的一种时序转换方法。通过该方法，可以解决DSP与传统输入输出设备时序不匹配的问题，从而实现DSP与8080、6800等时序兼容的或其它慢速读写周期的输入／输出设备的直接连接，如液晶显示模块、打印机、键盘等。这种时序转换方法能使DSP在工业控制和测试设备中获得更加广泛的应用。
有机/无机杂化材料负载金属配合物催化剂-Sol-gel技术的新利用

有机/无机杂化材料（Organic/inorganic hybrid, OIH）的出现，被认为是材料学发展中的一次革命。OIH早在工业时期就已经出现，只是到了近些年，人们才对OIH做出较明确的定义。OIH可以简单定义成既含有有机成分又含有无机成分，性质上兼有两种成分特性的固体材料。由于这种材料具有很多其他材料不具备的独特性能，广泛应用于光学、力学等许多领域。OIH作为催化剂已在很多化学反应中表现了很好的应用潜力。
江门市1385例骨密度检测报告

目的：探讨江门市区正常人群骨密度的变化规律，提高对骨质疏松症诊断的可预测性和可靠性。方法：采用法国产双能X线骨密度仪测量骨密度。正常人群1385例中男784例；女658例，分别作前臂、股骨上端及腰椎正位测量。骨质疏松者重点检测股骨上段和腰椎正位。结果：男、女前臂峰值骨量分别为（0.539±0.107）、(0.438±0.090)g/cm~2，均处于20～29岁年龄组；股骨上端的峰值骨量分别为(0.933±0.129)、(0.981±0.119)g/cm~2，腰椎峰值骨量分别为(1.007±0.097)、(0.956±0.072)g/cm~2，两组峰值骨量均处于30～39岁年龄组。男性60～69岁年龄组腰椎正位骨量为(0.969±0.122)g/cm~2，骨密度的变化较特殊，其余各组骨密度值随年龄增长而下降。结论：江门市区正常人群20岁以前男、女各组骨骼处于生长发育阶段，各部位骨密度（BMD）值持续增长；20～39岁男、女各部位骨量均达到峰值，40～49岁仍保持接近峰值的骨量，随后随年龄的增加BMD逐渐下降。女性由于受绝经的影响50岁以后BMD丢失更快，男性组在60～69岁由于普遍存在骨质增生、韧带及软组织钙化，腰椎BMD又有轻度回升后持续下降。
棉花温敏雄性不育系的选育与应用研究简报

到目前为止，棉花尚未找到一种具有育性转换特性的核不育系，其不育性不易保持；为了尽早选育出新类型的不育系，湖南农业大学经8年研究，已德育出遗传特性稳定，育性受温度控制，能一系两用的雄性不育系。配组试验表现出产量配合力强，纤维品质优势明显。2003年有2个组合进入湖南省棉花新品种区域试验。利用该系的制种方法，已申请国家发明专利，公布号：CN1382371A。
心肌肌钙蛋白I在冠状动脉旁路术中的变化及与围术期心肌梗死的关系

目的 研究心肌肌钙蛋白I（cTnI）在冠状动脉旁路术（CABG）中的变化及其与围术期心肌梗死（PMI）的关系。方法 观察与记录69例CABG患者术后cTnI水平和肌酸激酶同功酶（CK-MB）活性在不同时点的变化，记录心电图（ECG）及其他临床数据和事件。结果 6例（8.7%）PMI者与63例非PMI者相比cTnI和CK-MB显著增高（P < 0.01），其CABG后24小时cTnI平均值（27.1 ± 15.8）μg/L。血清cTnI值超过3.9μg/L时更多比例患者需要正性肌力药和血管活性药支持，且有更长的住院日，cTnI水平和心肺转流（CPB）时间与PMI最密切相关（P < 0.05）。结论 cTnI有助于PMI的早期诊断，估计术后心血管并发症的高危性，指导心肌保护。ECG低估了CABG后心肌损害或可能PMI。
天然免疫在脊柱关节病发病机制中的作用

天然免疫和获得性免疫是宿主防御过程中不同而又互为补充的两个方面。机体接触致病微生物后即迅速进行识别并产生抵抗病原体入侵的反应。发挥这一功能主要是巨噬细胞、树突状细胞和中性粒细胞。这些天然免疫细胞表达模式识别受体（pattern-recognition receptors, PRR），这些受体识别高度保守的病原体相关分子模式（pathogen-associated molecular patterns, PAMP）。天然和获得性免疫反应之间的联系是通过促炎细胞因子介导的；通过抗原递呈细胞上共刺激分子的上调，确保了T细胞的激活。
冠状病毒

冠状病毒(coronavirus)是一种常见的单链、非片段化、线性、正链RNA包膜病毒，能感染脊椎动物而引起，特别是呼吸系统疾病。此病毒可分三大类，感染不同动物，其遗传物质RNA表现出一种特殊的、有趣的、目前并不为人们完全所知的策略完成其自身繁殖。最近，科学家发现“非典型肺炎”的病原体为一种新型的冠状病毒，表现出其特别的基因组织结构，有别于已知的典型冠状病毒，相关研究正在进行中。
烟雾病八例临床报告

目的  探讨烟雾病的临床特征、影像学诊断及治疗。方法  对8例烟雾病患者的临床特征、辅助检查及治疗手段进行分析。结果  烟雾病临床表现以头痛（6例）、肢体瘫痪（5例）为主；数字减影血管造影（DSA）显示，颈内动脉虹吸部末端和大脑前或中动脉近端狭窄或闭塞，并有脑基底部异常血管网形成。保守治疗4例，手术治疗4例，均有改善；3例遗留神经系统后遗症。结论  脑DSA是诊断烟雾病的主要手段；脑缺血和脑出血的治疗方面存在一定的差异。
锌指蛋白的设计及其应用

人工设计的锌指蛋白一般包括两个结构域：DNA结合结构域和效应结构域。DNA结合结构域主要采用对DNA序列特异性识别结合的C_2H_2型锌指结构域，而功能结构域常常采用某些转录激活结构域、转录抑制结构域或某些酶的活性结构域。这样进行设计的锌指蛋白就可以在特定的核酸序列列上行使相应的功能，这对于目的基因的表达调控及蛋白质与核酸的相互作用研究提供了新的思路。
肿瘤坏死因子受体和配体超家族的新成员

骨原蛋白（OPG）/核因子κB受体激活剂的配体（RANKL）/核因子κB的受体激活剂（RANK）是肿瘤坏死因子受体和配体超家族成员。RANKL由成骨细胞前体/骨髓基质细胞和激活的T淋巴细胞合成，通过结合破骨细胞或树突状细胞表面的RANK受体，对此过程骨细胞的形成、融合、激活和存活，并有助于树突状细胞对抗原的提呈作用，OPG作为RANKL的假受体，对此过程具有抑制作用。此外，OPG/RANKL/RANK系统在调节淋巴系统发育、哺乳期动物乳腺腺泡的形成以及大动脉钙化中也起着重要的作用，是一组多功能的细胞因子系统。
膜通道研究再获诺贝尔奖

2003年的诺贝尔化学奖再次垂青膜通道领域的研究成果：Peter Agre因发现第一个细胞膜水通道蛋白，Roderick Mackinnon则因离子通道三维结构与功能机制方面的突破性成就而共同获奖。他们的研究成果为认识水和离子通过细胞膜的机制奠定了坚实的基础，同时开启了若干全新的生物医学研究领域。
马铃薯种薯贮藏技术研究初报

黔南州位于贵州的南部，农户贮藏马铃薯种薯均为木楼室内自然堆放贮藏（常规贮藏），从6月左右收获，堆至11月开始播种。由于贮藏时间长，贮藏方式简陋，夏季气温高，造成大量的烂种和长芽种。群众在播种时常去掉主芽和部分副芽后进行播种，至使种著质量差，造成马铃薯减产，质量下降。
我国企业竞争力现状分析及核心竞争力的培育

核心竞争力理论认为，核心竞争力是企业竞争力的基础。一个没有核心竞争力的企业，也就不存在真实的竞争力。如何培育并发展自身的核心竞争力，以获取持续的竞争优势，对我国企业来说是一项事关生死的紧迫任务。
管理层持股：沪市公司管理层的观点

目前政府有关部门对上市公司管理层股权激励的积极态度与理论界关于管理层收购利弊的热烈讨论构成了本次调查的缘起。调查发现：上市公司对管理层持股存在极大的需求，被调查者对通过管理层持股实现管理层收购表现出了相当的动力；目前影响管理层持股的重要因素并非“融资难”问题，而是政策的不明朗和法律法规的不健全；被调查者认为，管理层持股明显有助于优化公司的激励制度与效果，增强管理层的责任心，对公司治理和公司绩效有非常重要的作用，但管理层持股对公司内部控制、会计信息质量的积极影响表示；公司法和证券法最需要修改，相关规则亟待配套；管理层持股过程中的管理层基本信息、股仅转让信息和关联信息同样值得投资者关注；职位高低是决定管理层个人持股量大小的重要尺度；用股份抵押的形式向银行融资是最妥当的安排，但与《贷款通则》相抵触；在实惠方式上，“增量实施”比存量调整”更受欢迎；在受让价格上，净资产情结、优惠价格期望依然流行。文章认为，尽管“剧中人”观点的独立性无法与“剧外人”相比，但上述结论仍隐含着不少有益的政策启迪，相关政策建议也应引起足够的关注。
村社区性集体经济组织是否冠名合作社－－以福建省仙游县村经济合作社为例

本文对福建省仙游县村经济合作社的动作进行了实证研究。第一部分从村经济合作社是否遵循合作社原则、管理机构实际运行状况及在村民自治制度下的组织成本进行了分析，论证了村社区性集体经济组织没有必要戴合作社帽子的结论；第二部分通过对5个村经济合作社由村民委员会代行其领导机构职能这一管理模式实现村集体资产的保值增值的安例分析，从实践层面骓证了在村民自治制度下村民委员会代行社区性集体经济组织领导机构职能的可行性；第三部分根据农村集体资产实行承包、租赁、参股等经营，已从直接经营领域退出，村里主要负责村集体资产管理的现状和发展趋势，建议将村社区性集体经济组织界定为资产所有者和管理单位（尤如国有资产的管理部门），而不是一个企业性的经济，实体，由村民委员会直接管理。
宫颈癌中HPV16变异的CTSE与HPV16物理状态关系的分析

宫颈癌是最常见的女性生殖道恶性肿瘤，高危型人乳头瘤病毒16型（Human papillomavirus 16, HPV16）感染与其密切相关。该病毒的长控制区（long control region, LCR）内有细胞型特异性增强子（cell-type-specific enhancer, CTSE），是LCR的重要组成部分，参与诱导启动子P_（97）的活性，从而调控转化基因E_6/E_7转录的水平。本研究旨在检测HPV16 CTSE变异株在宿主细胞内的物理状态和CTSE变异的关系，探讨两者在宫颈癌发生、发展中的地位和作用，为深入揭示HPV的致癌机制奠定基础。
天祝县天然草原退化原因及治理对策

天祝县目前天然草原已普遍发生退化，其中退化比较严重的达到13.47万hm~2，占天然草原总面积的34.41%，重点分布于草原草场和山地草甸草场，沙化、碱化面积8.6万hm~2。草原退化是内因和外因共同作用的结果，有自然因素，也有人为因素。如气候变化、超载过牧、鼠虫危害、滥垦乱挖、不合理利用等。提出落实草原有偿承包责任制，改良退化草场，发展人工草地，实施退耕还草，强化草地监管力度等治理对策。
膨润土干燥剂制备及研究

膨润土中的蒙脱石晶层间能吸附和放出水分子，可用于干燥吸湿。研制的膨润土干燥剂无毒、无味、无腐蚀性，价格低廉，能再生反复使用。在军工、民用、医药、食品、卫生、环保等领域得到广泛应用，且有国际市场的潜力。
硅藻土提纯研究

四川某硅藻土矿为粉砂粘土质硅藻土和粘土质硅藻土，其硅藻以小环藻为主，适于生产助滤剂产品。本文探讨了硅藻土用作助滤剂的工艺条件，试验结果表明：采用擦妥分散-分级除杂-配浸除铁-焙烧处理工艺，可获得三种成份上完全合格的助滤剂产品。
双金属抗菌沸石研究

利用天然辉沸石和铜锌混合溶液进行液相离子交换，制得双组份抗菌沸石，同时研究了各因素对制备的影响。抑菌实验表明，该  玫瑰  抗菌性能良好，可用做填料制备抗菌材料。
钾长石的碱石灰烧结法综合利用研究

对利用碱石灰烧结法提取钾长石中的Al2O3、K2O和尾渣烧水泥，这一综合利用新工艺进行了试验研究。结果表明：熟料K2O的浸出率可达70％以上，熟料Al2O3的浸出率可达50％以上，而尾渣是硅酸盐水泥的良好原料。
热处理对钠－蒙脱石结构和物化性能的影响

对吉林省九台Na-膨润土在不同温度下进行了热处理活化，用分光光度法测定了稀酸对活化土中Fe、Al的溶出量；热处理后土-水体系的电导率、电动电势；并对比表面积、阳离子交换量和结构进行了研究。研究结果表明：热处理温度对土中Fe、Al的溶出量及其它的物理化学性能有明显的影响。
汽车刹车片产生噪音的原因及解决办法

汽车刹车片噪音的产生，与汽车制动盘或制动鼓有关，与车速、制动比压、温度等有关；选择湿法工艺，用轻质、硬度低、高气孔率的材料制作摩阻材料，对消除噪音有一定的贡献。
气候变暖条件下青藏铁路抛石路基的降温效果

根据多孔介质中流体热对流的连续性方程，动量方程和能量方程，应用伽辽金法导出了多孔介质对流换热的有限元公式，并对传统道路碴路基和抛石路基在未来50年青藏高原气温上升2.0℃情况下的温度变化进行了预报分析和比较，计算结果表明，在年平均气温大于-3.5℃或天然地表温度大于-1℃的地区，传统道碴路基以下5m内的冻土将会融化，路基将产生很大的融沉，对铁路造成很大的破坏，而抛石路基除了能抵消气候变暖的影响外，还能对路基下的冻土制冷，保证冻土路基的稳定，不至于使冻土融化，因此大力推荐该种路基作为青藏铁路高温冻土区的路基结构，以便最大限度地保护冻土区的铁路。
强强合作，联手塑造一流品牌－－访深圳市深宝－华城食品有限公司总经理颜泽松

去年得知广东华城食品有限公司（以下简称华城）与深圳上市公司深圳市深宝实业股份有限公司（以下简称深宝）共同投资近亿元成立的一个新公司——深圳市深宝-华城食品有限公司（以下简称深宝-华城），我不免有些好奇：广东华城食品有限公司近些年来发展速度奇快，并不缺资金，而且不事声张。由于好奇，我很想深入了解广东华城与深圳深宝组建新公司的想法和新公司的发展轨迹，但由于华城公司历来具有脚踏实地、不爱张扬的工作作风，直到12月初，借着参加深圳第五届国际食品展览会的机会，我才专程前往位于深圳市笋岗东路宝安大厦的公司总部探个究竟。
转铁蛋白-转铁蛋白受体系统在药物运输和定向给药中的应用

近年来，药物的定向运输和定点给药系统的研究已取得了可喜的进展，转铁蛋白-转铁蛋白受体系统在抗癌药物和蛋白质的定向运输以及作为基因载体在扩散的恶性肿瘤细胞基因治疗中的应用研究已接近临床使用阶段，药物经转铁蛋白-转铁蛋白受体介导通过血脑屏障进入脑内发挥药效的给药途径的研究也给脑疾病的治疗带来了巨大希望。
主动脉夹层23例临床报告

目的：探讨主动脉夹层的及时诊断和有效治疗。方法：回顾性分析23例主动脉夹层的病史和体征，检查和诊断，治疗和随访，并结合文献复习。结果：超声心动图、CT等检查确诊主动脉夹层，Stanford A型6例、B型3例、C型14例；治疗予药物控制血压，5例控制无效24小时内死亡；6例（C型）植入动脉内带膜支架；2例行外科手术；10例稳定出院，随访2-5年，猝死5例。结论：高血压病史、剧烈胸痛结合影像学检查可及时诊断该病，有效控制血压及动脉内带膜支架植入治疗有效，可改善近、远期预后。
2002年信息科学部一处项目受理情况通报

信息科学一处（电子与信息系统科学处）本科学处支持的研究主要涉及信息与信息系统、信号分析与信号处理、电路与系统、电磁场与电磁波、电子学理论及其应用等研究领域。能够支持多媒体业务，与互联网相结合的网络与无线通信成为该领域的研究重点。真空电子学、等离子体电子学、计算电磁学、纳米电子学、生物电子学和生物信息处理也是本学科的重要研究方向。
泥石流危险性动量分区方法与应用

运用泥石流运动数值模拟和GIS相结合的方法模拟泥石流出山口后的运动全过程，求得泥石流流速和流深分布，确定泥石流过程中泛滥范围内任一点的最大动量，建立了泥石流危险性动量分区模型Z=Khv。根据考察和实验资料对委风瑞拉首都加拉加斯的Chacaito沟百年一遇泥石流运动过程进行了模拟，利用动量分区方法划分出泥石流危险区。
气孔开放时保卫细胞液泡中某些高聚物解聚对渗透调节的作用

电子显微镜观察显示：蚕豆（V.faba L）叶片气孔开放前后，保卫细胞液泡（GCV）中颗粒的平均体积下降了约3个数量级，而分布密度增加了约2个数量级，同时用激光共聚焦显微术的荧光比值法对气孔开放过程的跟踪测定说明，在第1个可分辨的气孔开放动作前10～30s时GCV的pH有一个约-0.5单位的变化，一个快速的气孔开放过程紧随其后，在约100～200s的时间内达到稳定的约12μm的开度，提出了一个由-△pH变化诱导的与GCV内某些高聚物解聚有关的渗透调节模式，该模式所描述的渗透调节过程避免了传统“化学渗透”假说所依赖的耗能巨大的逆浓度梯度的跨膜运输，是对气孔运动的多元调控假说的补充，同时也为植物中其他快速运动机理的研究拓宽了思路。
细胞色素c氧化酶薄膜中还原型双铜簇的MLCT吸收带的辨认

低浓度的连二亚硫酸钠可以诱导浸在酸性磷酸缓冲液中的固态薄膜中细胞色素c氧化酶的双铜和血红素A中心还原，但铁铜双核中心仍处在氧化态，这种变化在差光谱上表现为426nm的负峰和408nm左右的正峰，前者表示氧化型血红素A的减少，即Fea^3+→Fea^2+变化，后者来自还原型双铜族的金属配位电荷转移（MLCT）跃迁，而非来自血红素A，这种较强的Cu（I)的Soret MLCT带的分辨将有利于克服金属蛋白中铜的吸收被铁所掩盖而产生的研究障碍。
腹腔镜筋膜内子宫切除术122例

经典腹腔镜筋膜内子宫切除术（CISH）采用四穿孔，而我院自2001年3月～2003年1月实施三穿孔CISH手术共122例，现报道如下。一、临床资料患者年龄38～47岁，平均45岁，均有生育史，有腹部手术史35例。疾病种类：子宫肌瘤90例，子宫腺肌瘤24例，难治性功血8例。妇科检查：子宫正常大8例，增大如孕6周25例，孕7～9周82例，孕10～12周7例。术前均行B超检查，部分有不规则阴道出血史者行诊断性刮宫排除恶性病变。随机抽取64例同期行硬膜外麻醉下经腹子宫切除者为对照，年龄、病史、子宫大小无显著性差异。
无痛分娩在临床上的应用

为了提高分娩期质量，减少立妇分娩疼痛，降低剖癌产率，我院自2001年以来开展无痛分娩，取得了良好的效果，现报告如下。一、对象选自2002年1～2月在我院分娩单胎头位的产妇809例，其中335例行无痛分娩，为观察组。474例未行无痛分娩，为对照组。分析比较两组分娩方式、产后出血、新生儿情况、以及手术指征。两组产科情况相似，无显著差异。
颈胸椎黄韧带骨化的诊断和治疗

近年来随着影像学的飞速发展，颈胸椎管内黄韧带骨化亦被发现。此病主要表现为脊髓压迫及/或脊神经受压症状。手术行椎板减压加骨化之黄韧带切除，若合并Arnold-Cliari氏畸形应行后颅凹减压及/或脊髓中央管-蛛网膜下腔分流术可达治愈。1989年～2001年共收治了10例颈胸椎黄韧带骨化引起脊髓及脊神经压迫。
多发性硬化患者脑脊液中白细胞介素—6的变化和临床意义

目的 探讨多发性硬化患者(MS)脑脊液中白细胞介素—6(IL—6)的变化及IL-6在多发性硬化发病过程中的作用。方法 选取20例MS患者与12例其他非炎症性神经系统疾病(NIND)患者，用ELISA方法测定其脑脊液中IL-6水平，并测定了部分经糖皮质激素治疗后患者脑脊液中IL-6水平。结果 MS患者脑脊液中IL-6水平明显高于NIND患者脑脊液水平，重型患者水平高于轻型患者水平，且IL—6水平与加强评分中度相关；经治疗后患者脑脊液IL-6水平明显下降。结论 IL—6可能参与MS的发病过程，并与病情相关。