mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
神经系统临床教学课程整合的实践与思考

21世纪,医学模式从“生物学模式”转变为“生物-心理-社会医学模式”,从“治疗型模式”转变为“预防、保健、群体和主动参与模式”;世界卫生组织(WHO)提出未来五星级医生的标准为:卫生保健提供者,医疗行为决策者,健康教育者,社区卫生领导者,医疗服务管理者。现代医学科学的高度分化与高度综合对医学人才的培养提出了更高的要求,全面推进和实现医学创新教育已经成为目前医学教育改革的共识与趋势,其目的就是要培养学生的创新意识与创新习惯。医学教育模式和课程整合是实现医学创新教育的重要途径与目标,以器官/系统为基础的医学课程整合是目前医学教育模式改革的发展趋势。为此,本研究对第三军医大学临床医学八年制神经系统临床教学课程进行了整合,现报道如下。
玻璃酸钠联合氨基葡萄糖治疗骨性膝关节炎的疗效观察

目的观察玻璃酸钠联合氨基葡萄糖治疗骨性膝关节炎的疗效。方法将270例骨性膝关节炎患者,随机分为玻璃酸钠联合氨基葡萄糖胶囊的观察组,及塞来昔布片治疗的对照组,5周为一个疗程。观察两组患者VAS、膝关节功能评分及临床疗效。结果治疗后,两组患者VAS及膝关节功能评分均较治疗前明显改善(P< 0.05或0.01);治疗3周后,两组间的评分无明显差异;治疗6周后,观察组的评分均明显优于对照组(P<0.05)。观察组的有效率为76.3%,对照组为62.2%,观察组高于对照组(P<0.05)。结论玻璃酸钠联合氨基葡萄糖胶囊可有效缓解骨性膝关节炎患者的疼痛,改善关节活动度,促进骨关节修复,具临床推广价值。
干扰素α - 2b联合阿德福韦酯治疗HbeAg阳性慢性乙型肝炎的临床观察

目的观察干扰素联合阿德福韦酯治疗HBeAg阳性慢性乙型肝炎的临床疗效。方法患者90例,随机分为3组,联合治疗组给予阿德福韦酯10 mg, 1次/d,口服,干扰素α - 2b 5 MU,隔日一次皮下注射;阿德福韦酯组给予阿德福韦酯10 mg, 1次/d,口服;干扰素组给予干扰素ct - 2b 5 MU,隔日一次皮下注射;疗程均为48周。监测3组患者治疗12,24及48周以及随访结束24周时的ATL变化、HBV血清标志物、HBV DNA水平变化。结果治疗12,24,48周以及随访结束24周时联合治疗组HBV DNA阴转率分别为56.7%,86.7%,96.7%和93.3%;ALT复常率为分别为53.3%,96.7%,96.7%,90.0%,均优于干扰素组(P <0.05);HBeAg转阴率分别为30%,46.7%,66.7%,63.3%,HBeAb阳转率分别为0,40.0%,60.0%,53.3%,均显著高于阿德福韦酯组和干扰素组(P<0.05)。三组病例均以野毒株为优势株,未发现变异。结论干扰素联合呵德福韦酯治疗慢性乙型肝炎疗效优于单用干扰素及单用阿德福韦酯。
Fabrication and Properties of Porous Si_3N_4 Ceramic with High Porosity

A novel process combining oxidation-bonding and sintering was developed to fabricate porous Si_3N_4 ceramic with high porosity. After sintering at 1800℃, the SiO_2 in porous Si_3N_4 ceramic transforms into Si_2N_2O because of the reaction of SiO_2 and Si_3N_4. Due to the reaction of SiO_2 and carbon, the porosity of porous Si_3N_4 ceramic increases obviously from 40.2% to 76.8% with the weight decreasing by 35.6%. As the porosity increases, the dielectric constant and loss of the porous Si_3N_4 ceramic decrease obviously from 3.08 to 1.61 and from 3.70×10~(-3) to 0.74×10~(-3), but due to the production of Si_2N_2O whose mechanical properties are much higher than SiO_2 and the increase of the bonding strength among Si_3N_4 particles, the flexural strength and the fracture toughness of the porous Si_3N_4 ceramic decrease from 55 to 39 MPa and from 0.7 to 0.5 MPa-m~(1/2), respectively, but its Vickers hardness increases from 1.2 to 1.3 GPa.
Relationship Between Changes of River-lake Networks and Water Levels in Typical Regions of Taihu Lake Basin, China

The typical regions of the Taihu Lake Basin, China, were selected to analyze the variation characteristics of river-lake networks under intensive human activities. The characteristics of the fractal dimension of river networks and lakes for different periods were investigated and the influences of river system evolution on water level changes were further explored through the comparison of their fractal characters. The results are as follows: 1) River network development of the study area is becoming more monotonous and more simple; the number of lakes is reducing significantly, and the water surface ratio has dropped significantly since the 1980s. 2) The box dimension of the river networks in all the cities of the study area decreased slowly from the 1960s to the 1980s, while the decrease was significant from the 1980s to the 2000s. The variations of lake correlation dimension are similar to those of the river network box dimensions. This is unfavorable for the storage capacity of the river networks and lakes. 3) The Hurst exponents of water levels were all between 0.5 and 1.0 from the 1960s to the 1980s, while decreased in the 2000s, indicating the decline in persistence and increase in the complexity of water level series. The paper draws a conclusion that the relationship between the fractal dimension of river-lake networks and the Hurst exponents of the water level series can reveal the impacts of river system changes on flood disasters to some extent: the disappearance of river networks and lakes will increase the possibility of flood occurrence.
Roles and Functions of Tourism Destinations in Tourism Region of South Anhui: A Tourist Flow Network Perspective

Theoretic and practical significance has been highlighted in the research of the roles and functions of destinations, as destinations are restricted by the spatial structure based on tourist flow network from the perspective of relationship. This article conducted an empirical analysis for Tourism Region of South Anhui (TRSA) and revealed the necessity and feasibility of studying the roles and functions of destinations from tourist flow network′s perspective. The automorphic equivalence analysis and centrality analysis were used to classify 16 destinations in TRSA into six role types: tourist flow distribution center, hub of tourist flows, passageway destination, common touring destination, attached touring destination, and nearly isolated destination. Some suggestions were given on suitable infrastructure construction and destinations service designs according to their functions in network. This destination role positioning was based on tourist flow network structure in integral and macroscopic way. It provided an important reference for the balanced and harmonious development of all the destinations of TRSA. In addition, this article verified the applicability of social network analysis on tourist flow research in local scale, and expanded this method to destination role and function positioning.
Responses of Soil Fauna Structure and Leaf Litter Decomposition to Effective Microorganism Treatments in Da Hinggan Mountains, China

Microorganisms are nutritious resources for various soil fauna. Although soil fauna grazing affects microorganism composition and decomposition rate, the responses of soil fauna and leaf litter decomposition to added microorganism is little understood. In this study, in the coniferous and broad-leaved mixed forest of Tahe County in the northern Da Hinggan Mountains, China, three sampling sites (each has an area of 10 m2) were selected. The first two sites were sprinkled with 250 times (EM1) and 1000 times (EM2) diluted effective microorganism (EM) preparations evenly, and the third site was sprinkled with the same volume of water as a control site. The responses of soil fauna structure and leaf litter decomposition to EM treatment were conducted during three years. The results revealed that EM treatment resulted in significant increase of soil organic matter. The number of soil fauna in the EM1 and EM2 sites increased by 12.88% and 2.23% compared to the control site, and among them springtails and mites showed the highest increase. However, the groups of soil fauna in the EM1 and EM2 sites decreased by 6 and 9, respectively. And the changes in the diversity and evenness index were relatively complicated. EM treatment slowed the decomposition of broad-leaved litter, but accelerated the decomposition of coniferous litter. However, the decomposition rate of broad-leaved litter was still higher than that of coniferous litter. The results of this study suggested that the added microorganisms could help individual growth of soil fauna, and this method led to a change in the process of leaf litter decomposition. This paper did not analyze the activity of soil microorganisms, thus it is difficult to clearly explain the complex relationships among litter type, soil fauna and soil microorganisms. Further research on this subject is needed.
2012年度地理学基金项目评审与成果分析

着重分析2012年度面上项目、青年基金项目、地区基金项目及青年科学基金—面上项目连续资助项目的申请与资助情况,2011年度在研及结题项目的进展情况,申请过程及结题报告中暴露的问题;介绍了2011—2012年地理学学科"研究方向"、"关键词"编制及试用情况。
胸部贯通伤法医学鉴定1例

现行《人体重伤鉴定标准》第六十一条规定胸部损伤引起血胸或者气胸,并发呼吸困难、胸部损伤致成纵隔气肿的应评定为重伤。本例损伤程度鉴定存在两种意见,一种认为:纵隔气肿诊断明确,应评定为重伤。另一种认为:外伤性气胸未出现呼吸困难应属轻伤。笔者根据以下理由同意第二种意见:张某伤后虽有气短的主诉,但无呼吸困难症状;其X线片示左肺压缩(65 %)未达70%以上;纵隔少量气肿,亦不会产生严重的病理生理变化,且经治疗半月气肿消失。本例如评定为重伤,不符合《刑法》第九十五条规定。
听觉事件相关电位技术在意识障碍评估中的应用

意识障碍是严重脑损伤后的常见症状。意识包括觉醒和意识内容两方面。上行网状激活系统和大脑皮质的广泛损害可导致不同程度的觉醒水平障碍,而意识内容变化则主要由于大脑皮质病变造成。对意识障碍准确客观的评价在了解患者病情的严重程度及预后判断中具有十分重要的作用。然而,对意识障碍的客观评估是目前临床上的一个难点。目前,意识障碍的评估主要依靠患者的临床表现及各种量表评估,主观性强且难以反映意识的微小变化。神经电生理学检查因其客观性强,时间分辨率高等特点,在评估这些意识障碍患者方面具有一定的优势,并在一定程度上显示出临床应用前景。下面对目前研究中应用较多的听觉事件相关电位技术在意识障碍评估中的应用做一介绍。
Dragon Tails:Convergent Caudal Morphology in Winged Archosaurs

In the tails of dromaeosaurid dinosaurs and rhamphorhynchid pterosaurs, elongate osteological rods extend anteriorly from the chevrons and the prezygapophyses. These caudal rods are positioned in parallel and are stacked dorsoventrally. The fully articulated and three-dimensionally preserved caudal series of some dromaeosaurid specimens show that individually these caudal rods were flexible, not rigid as previously thought. However, examination of the arrangement of the caudal rods in cross-section indicates that the combined effect of multiple caudal rods did provide substantial rigidity in the dorsoventral, but not in the lateral, plane. The results of digital muscle reconstructions confirm that dromaeosaurids and rhamphorhynchids also shared greatly reduced caudofemoral muscles in the anterior tail region. The striking similarities between the tails of dromaeosaurids and rhamphorhynchids suggest that both evolved under similar behavioral and biomechanical pressures. Combined with recent discoveries of primitive deinonychosaurs that phylogenetically bracket the evolution of dromaeosaurid caudal rods between two arboreal gliding/flying forms, these results are evidence that the unique caudal morphologies of dromaeosaurids and rhamphorhynchids were both adaptations for an aerial lifestyle.
Zircon U-Pb Age and Geochemistry of the Ore-hosting Ultramafic Complex of Zhou'an PGE-Cu-Ni Deposit,Henan Province,Central China

The Zhou’an PGE-Cu-Ni deposit was recently discovered in the Qinling orogenic belt bound by the Yangtze and the North China Cratons. It is a blind deposit thoroughly covered by the Cenozoic alluvial sediments in the Nanyang Basin. As the first large PGE-Cu-Ni deposit discovered in the Qinling-Dabie-Sulu orogenic belt, its geological and geochemical characteristic, isotope age, genesis and tectonic setting are of wide concern in both scientific studies and ore exploration. In this contribution, we report the results obtained from a pioneering study. The Zhou’an ultramafic complex is ferruginous, with m/f=4.79-5.08, and shows the nature of tholeiite series. It is rich in light rare earth elements, Rb, Th, U, La, Sm, Zr and Hf, and poor in heavy rare earth elements, Nd and Ta, suggesting an intraplate setting. It has high ~(87)Sr/~(86)Sr and low ~(143)Nd/~(144)Nd ratios. The ratios of Zr/Nb, La/Nb, Ba/Nb, Rb/Nb, Th/Nb, Th/La and Ba/La, suggest the magma originated from lithosphere mantle. The Fo values of olivine and Pd/Ir-Ni/Cu diagram suggest primary magma was High Mg basalt. The laser ablation inductively coupled plasma atomic emission spectroscopy zircon U-Pb age is 641.5±3.7 Ma.
Petrographic and Geochemicial Characteristics of the Kiziloren Formation (Upper Triassic-Lower Jurassic) in the Akpinar (Konya,Turkey) Area

This paper describes the occurrence of dolomite and the mechanism of dolomitization of the Upper Triassic-Lower Jurassic Kiziloren Formation in the autochthonous Bolkardagi unit of the middle Taurus Mountains in south western Turkey. Dolomites were analyzed for geochemical, isotopic and crystallographic variation. Dolomites occur as a replacement of precursor carbonate and cement. The dolomite crystals range from <10 to ~1000 μm existing as both replacements and cements. Sr concentrations range between 84 and 156 ppm, and the molar Sr/Ca ratios of dolomitizing fluids are estimated to range between 0.0066 to 0.013 ratios. Dolomites are Ca-rich (with average CaCO_3 and MgCO_3 equal to 56.43 and 43.57 mol%, respectively) and they are non-stoichiometric, with an average Sr=116 ppm, Na=286 ppm, Mn=81 ppm, Fe=1329 ppm, and δ~(18)O and δ~(13)C ranges from -0.6‰ to -6.1‰ Pee Dee Belemnite [PDB], and +1.2 to +3.9‰ PDB. The North American Shale Composition [NASC]-normalized rare earth element (REE) values of the both limestone and dolomite sample groups show very similar REE patterns characterized by small positive Eu (mean=1.32 and mean=1.42, respectively) and slightly or considerably negative Ce (mean=0.61 and mean=0.72, respectively) anomalies and a clear depletion in all REE species. The Kiziloren Formation dolomites have been formed as early diagenetic from mixing zone fluids at the tidal-subtidal environment and at the late diagenetic from basinal brines at the shallow-deep burial depths.
复方利多卡因乳膏贴敷用于小儿静脉穿刺的临床观察

小儿手术大多在全身麻醉下完成,但麻醉诱导前的操作如肌肉注射、静脉穿刺等不适引起患儿恐惧、紧张和哭闹是不可避免的。患儿哭闹后口鼻分泌物增多,也对呼吸道管理带来诸多不便。我院对岁的儿童麻醉前在静脉穿刺部位用复方利多卡因乳膏贴敷,以减轻静脉穿刺时引起的疼痛,收到良好效果,提高了麻醉的安全性。
聚乙二醇干扰素对普通干扰素治疗失败慢性乙型肝炎患者的疗效

目的研究聚乙二醇干扰素α-2a对普通干扰素治疗无应答或复发慢性乙型肝炎患者的疗效。方法27例符合抗病毒治疗条件的HBeAg阳性慢性乙型肝炎患者分为两组,A组18例,既往无抗病毒药物使用史;B组9例,既往曾使用过普通干扰素抗病毒。两组均接受聚乙二醇干扰素α-2a180μg,皮下注射,每周1次,疗程24周。观察治疗后ALT、HBV DNA定量、HBV血清学标志物的改变。结果治疗24周后,A组HBV DNA转阴率、HBeAg转阴率、ALT复常率分别为33%、22%、50%;B组分别为44%、22%、22%(P均>0.05)。治疗过程中A、B两组患者血清HBV DNA均持续下降,治疗24周后两组病毒量平均下降值分别为3.56log10copies/ml、4.16log10copies/ml(P均>0.05)。治疗过程中两组患者均未出现需要停药的严重不良反应。结论普通干扰素治疗无应答或复发的慢性乙型肝炎患者选用聚乙二醇干扰素α-2a抗病毒治疗24周安全、有效。
HPLC-ELSD法测定蒺藜粗皂苷中3种甾体皂苷元

目的同时测定蒺藜粗皂苷中海柯皂苷元、薯蓣皂苷元和替告皂苷元的量。方法采用HPLC-ELSD法,色谱柱为Agilent Zorbax SB-C_(18)柱(250 mm×4.6 mm,5 μm),流动相为甲醇-水(86∶14),漂移管温度100 ℃,载气体积流量2.5 L/min。结果海柯皂苷元、薯蓣皂苷元和替告皂苷元分别在114.1~1 141.0 μg/mL(R~2=0.999 2),16.88~168.80 μg/mL(R~2=0.999 4),78.60~786.00 μg/mL(R~2=0.999 3)呈良好线性关系;蒺藜粗皂苷中海柯皂苷元、薯蓣皂苷元和替告皂苷元的平均回收率分别为99.7%(RSD为1.6%)、99.3%(RSD为1.4%)、99.4%(RSD为1.1%)。结论该方法简便、准确、快速,且专属性良好,可用于蒺藜粗皂苷的质量评价。
基于一测多评的中药多成分定量研究进展

中药成分的复杂多样决定了中药质量控制模式必须采用多成分定量和多指标质量控制,但中药化学对照品性质不稳定、货源严重紧缺和检测成本昂贵等,严重阻碍了这一模式的发展,成为中药现代化的瓶颈问题之一。“一测多评”分析方法通过测定一个对照品易得的成分实现中药多成分定量,是适合中药特点的多指标质量控制和评价模式。系统阐述了“一测多评”法的基本原理及其在中药多成分定量中的研究进展,总结了“一测多评”法在中药材、中药饮片及中药复方制剂中的应用,探讨其优势及其在实际应用中存在的关键问题。提出“一测多评”法的研究思路在20多种中药材、中药饮片及中药复方制剂中得到了验证,有望成为中药质量控制的未来发展趋势。
中国超级稻育种技术的创新与发展

阐述了超级稻培育在保障国家粮食安全中的重要地位,介绍了中国水稻研究所超级稻研究团队在育种技术创新方面取得的成绩,探讨了超级稻育种技术的发展方向,明确了超级稻育种第二阶段的目标。
空气中工作的新型锂空气电池

近年来汽车用蓄电池的开发成为关注焦点。锂离子电池与其它可充电电池相比,具有比能量大、工作电压高、循环寿命长、自放电低等优点,已成为21世纪重要的新型能源之一。但日本新能源产业技术综合开发机构(NEDO)的Li-EAD计划中设定了至2030年蓄电池达到700 Wh/kg的高性能指标。这是目前比能量较大的锂离子电池也不能达到的数值。而锂空气电池拥有非常高的能量,比能量可大于1 000 Wh/kg,存储时间可以很长。与其他原电池相比,锂空气电池的功率比较低,更适合用于混合系统。
薄膜太阳电池技术进展市场前景

美国投资机构Maxim Group最新统计数据显示,受美国、欧洲双反调查的影响,中国最大的10家光伏企业的债务累计已高达175亿美元,约合1 110亿元人民币。但是,业内人士认为,所有中国光伏产业的负面消息,说的都是晶硅太阳电池,而不是薄膜太阳电池,薄膜太阳电池正在以每年5%~10%的市场占有率快速增长。
用laboman中间件实现血常规一步法自动筛查

目的用laboman中间件实现血常规结果一步法自动审核,提高筛查速度及检验质量。方法将本科室血常规的34条审核规则(计数类规则、仪器报警信息类规则、特殊病区和特殊年龄规则、以往检测结果比较规则)在laboman内编制成计算机运算法则,同时开通Sysmex血液分析仪的双向通信功能,形成自动筛查软件并与常规多步骤筛查方法比较。结果(1)在18 261份样本的审核结果分析中,一步法自动审核筛查出4 325份(23.7%)需复检样本,13 936(76.3%)份样本检测后可即时发送报告。(2)一步法自动审核流程使检验报告回报时间(turnaround time,TAT)从2005年9月的28 min缩短为2011年9月的15.7 min。(3)随机选择953份样本对常规多步骤筛查和一步法自动筛查流程进行比较,常规多步骤筛查流程耗时49 min,漏审率为1.15%;而一步法自动筛查瞬间完成且漏检率为零。结论一步法自动筛查流程的建立,降低了报告审核环节和差错率,提高样本处理能力,缩短检验报告的TAT,实现血常规检测分析后过程的智能化高效报告审核流程。
The mechanism of the anticancer function of M1 macrophages and their use in the clinic

M1-type macrophages are capable of inducing lysis in various types of cancer cells, but the mechanism of action is unclear. It has been noted that an "unknown protein" produced together with protease by activated macrophages is responsible for this action. Activated M1 macrophages have been recently reported to produce family 18 chitinases, all of which have been named chitotriosidase. Our experiments have demonstrated that family 18 chitinases work together with proteases and can damage various cancer cells both in vitro and in vivo. Thus, in this article, we suggest that the 50-kDa chitotriosidase is the reported "unknown protein". In addition, we discuss how to properly stimulate activated M1 macrophages to produce 50-kDa chitotriosidases and proteases for destroying cancer cells. Because family 19 chitinase has recently been reported to kill cancer cells, we also discuss the possibility of directly using human family 18 chitotriosidase and the humanized plant family 19 chitinase for cancer treatment.
A 2. 7 kV 4H - SiC JBS Diode

4H silicon carbide (4H-SiC) junction barrier Schottky (JBS) diode with breakdown voltage higher than 2.7 kV and active area of 2.8 mm2 has been successfully fabricated. The design, the fabrication, and the electrical characteristics are reported. Numerical simulations have been performed to select the doping level and thickness of the drift layer and the effectiveness of the edge termination technique. The epilayer properties of the N-type are 18 μm with a doping of 3.5×10~15 cm~(-3). The diodes are fabricated with a floating guard rings edge termination. The on-state voltage is2.15 V at J_f =350 A.cm~(-2).
Research on IGBT Drive Circuit Based on 2QD30A17K-I Driver

The insulated gate bipolar transistor (IGBT) has become the most popular controllable power switching device in the design of power electronics industry. As the interface of power circuit and control circuit in power source, the IGBT drive circuit should be with short transition time and the function of isolating safely and monitoring correctly the short-circuit and over-voltage fault.This paper presents the short-circuit protection theory and relative parameter selecting rules,based on the research on 2QD30A17K-I, the representative of high voltage and high power driver.
新型电力电子器件专辑一特邀主编评述

电力电子技术是实现高效节能节材、改造传统产业并促进机电一体化的关键技术,它是弱电控制与强电运行之间,信息技术与先进制造技术之间的桥梁,是我国国民经济的重要基础技术,是现代科学、工业和国防的重要支撑技术。电力电子器件是电力电子技术的核心和基础。近几年来,中国电力电子器件的市场一直保持快速增长的势头。2011年中国电力电子器件市场规模达到1 068亿元,较2010年增长5. 2%。在分立器件中,高频大功率新型电力电子器件IGBT,VDMOS和FRED是增长最快的器件,今后几年的年增长速率将达到10%以上。
Energy consumption of electrooxidation systems with boron-doped diamond electrodes in the pulse current mode

A pulse current technique was conducted in a boron-doped diamond (BDD) anode system for electrochemical wastewater treatment. Due to the strong generation and weak absorption of hydroxyl radicals on the diamond surface, the BDD electrode possesses a powerful capability of electrochemical oxidation of organic compounds, especially in the pulse current mode. The influences of pulse current parameters such as current density, pulse duty cycle, and frequency were investigated in terms of chemical oxygen demand (COD) removal, average current efficiency, and specific energy consumption. The results demonstrated that the relatively high COD removal and low specific energy consumption were obtained simultaneously only if the current density or pulse duty cycle was adjusted to a reasonable value. Increasing the frequency slightly enhanced the COD removal and average current efficiency. A pulse-BDD anode system showed a stronger energy saving ability than a constant-BDD anode system when the electrochemical oxidation of phenol of the two systems was compared. The results prove that the pulse current technique is more cost-effective and more suitable for a BDD anode system for real wastewater treatment. A kinetic analysis was presented to explain the above results.
基于"失眠恶性循环"假说探讨四逆散对失眠症的干预效应

上述研究表明,通过改善"失眠恶性循环"治疗失眠是有效的,而这也从另一方面验证了四逆散治疗失眠症的可行性。从这一理论出发,临证选方用药的切入点为"调节失眠引起的神经心理异常,打破失眠恶性循环",治疗目标在于"重构身心平衡",将对临床应用催眠的单一治疗方案进行完善。因此,四逆散的临床应用在神经心理领域具有极大的推广潜力;同时也为失眠继发神经心理异常疾病的有症可据、有证可辨、有机可察、有药可治提供依据。
魏品康运用对药治疗胃癌经验总结

本院魏品康教授是师承制博士导师、博士后导师,出身中医世家,从医40余载,临证经验丰富,尤其在药物运用方面颇有心得,且擅长使用对药。笔者有幸师从于侧,受益匪浅,兹采撷其应用对药治疗胃癌经验之一二,以飨同道。
自制会阴冷敷垫治疗产后会阴水肿疗效观察

本观察结果显示,会阴冷敷垫外敷可促进产后会阴切口的愈合,水肿改善明显,减轻疼痛,缩短产后住院时间,且简便易行,无不良作用,具有中医药简、便、廉、验、效的特色优势。
运脾方早期干预对营养缺乏性亚健康儿童食量和皮下脂肪厚度等的影响

孙远岭教授基于临床实践提出了儿童"营养缺乏性亚健康"概念,并应用经验方运脾方进行早期干预,收效显著。皮下脂肪厚度是估价儿童青少年营养状态的指标之一,在本临床观察中,我们发现应用运脾方干预后在增加食量的同时,体质量和皮下脂肪厚度都有显著增加,进一步明确了运脾方对营养缺乏性亚健康儿童早期干预可增加体质量、增强食欲、提高食量的良好效果,为儿童营养缺乏性亚健康提供有效的中医药早期干预方法,以减少形成营养不良及其相关病证的发病率,为提高儿童的整体健康水平起到积极的作用。
Examination of Element Concentrations in Groundwater by ICP-MS for Monitoring of Pre-Earthquake Activities

This study presents the results of hydrogeochemical studies carried out in Zeytun thermal springs in Kahramanmaras, located South Middle Anatolia-Turkey. More than 90 thermal water samples were collected on a regular basis from 2006 to 2008 to measure element concentrations as a monitor of earthquake precursors. Water samples were analyzed using ICP-MS. The observed B, Ba, Br and Ge concentrations for 16 months are in ranges of 79~422, 103~167, 28~93 and 0.3~1.2 μg·L~(-1), respectively. Chloride concentrations for these periods are in range of 7~21 mg·L~(-1). The data identify some element anomalies before earthquakes. These anomalies are characterized by decreases up to 158% in Ba and Cl concentrations. The occurrence of these anomalies can be attributed to stress/strain induced pressure changes in the subsurface water systems. It can be suggested that the thermal springs in the fault line area are ideal sites for precursors of earthquakes.
Spontaneous remission of Pneumocystis jiroveci pneumonia in 2 non-AIDS immunocompromised patients

Pneumocystis jiroveci (P. jiroveci) pneumonia (PCP) in non-AIDS immunocompromised patients is much more critical than that in AIDS patients.1 Without treatment, mortality of PCP in immunocompromised patients approaches 100 percent, and there were no reports of spontaneous remissions of PCP without anti-PCP therapy. Here we report 2 non-AIDS immunocompromised patients in whom PCP developed and remitted without treatment.
Varied response of the pulmonary arterial endothelium in a novel rat model of venous thromboembolism

Background The experimental studies of venous thromboembolism (VTE) as an entity and the response of the pulmonary arterial endothelium after VTE are still rare. The objective of this study was to observe changes in the pulmonary arterial endothelium using a novel rat model of VTE. Methods Rats were allocated to the VTE (n=54) or control groups (n=9). The left femoral vein was blocked using a microvessel clip to form deep vein thrombosis (DVT). One, four or seven-day-old thrombi were injected into the right femoral vein to induce DVT-pulmonary thromboembolism (DVT-PTE). The rats were sacrificed 1, 4 or 7 days later (D_(n (1,4,7)) Pn_(i,4,7) subgroups (n=6)), and the lungs were examined using light and electron microscopy. Results On gross dissection, the rate of DVT formation was higher on day 1 (D_1P_n: 100%, 18/18) than day 4 (D_4P_n: 83%, 15/18; x~2=5.900, P=0.015) or day 7 (D_7P_n: 44%, 8/18; x~2=13.846, P=0.000). On gross dissection, the positive emboli residue rate in the pulmonary arteries was lower in the subgroup (39%, 7/18) than the D_4P_n(73%, 11/15; x~2=3.915, P=0.048) and D_7P_n subgroups (100%, 8/8; x~2=8.474, P=0.004); however, light microscopy indicated the residual emboli rate was similar in all subgroups. Hyperplasia of the pulmonary arterial endothelium was observed 4 and 7 days after the injection of one-day-old or four-day-old thrombi. However, regions without pulmonary arterial endothelial cells and intra-elastic layers were observed one day after injection of seven-day-old thrombi. Conclusions This novel model closely simulates the clinical situations of thrombus formation and is ideal to study pulmonary endothelial cell activation. The outcome of emboli and pulmonary arterial endothelial alterations are related to the age and nature of the thrombi.
Tissue engineering in urethral reconstruction-an update

The field of tissue engineering is rapidly progressing. Much work has gone into developing a tissue engineered urethral graft. Current grafts, when long, can create initial donor site morbidity. In this article, we evaluate the progress made in finding a tissue engineered substitute for the human urethra. Researchers have investigated cell-free and cell-seeded grafts. We discuss different approaches to developing these grafts and review their reported successes in human studies. With further work, tissue engineered grafts may facilitate the management of lengthy urethral strictures requiring oral mucosa substitution urethroplasty.