mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Intestinal absorption characteristics of imperialine: in vitro and in situ assessments

Aim: Imperialine is an effective compound in the traditional Chinese medicine chuanbeimu (Bulbus Fritillariae Cirrhosae) that has been used as antitussive/expectorant in a clinical setting. In this study we investigated the absorption characteristics of imperialine in intestinal segments based on an evaluation of its physicochemical properties. Methods: Caco-2 cells were used to examine uptake and transport of imperialine in vitro, and a rat in situ intestinal perfusion model was used to characterize the absorption of imperialine. The amount of imperialine in the samples was quantified using LC-MS/MS. Results: The aqueous solubility and oil/water partition coefficient of imperialine were determined. This compound demonstrated a relatively weak alkalinity with a pK_a of 8.467±0.028. In Caco-2 cells, the uptake of imperialine was increased with increasing pH in medium, but not affected by temperature. The apparent absorptive and secretive coefficient was (8.39±0.12)×10~(-6) cm/s and (7.78±0.09)xl0~(-6) cm/s, respectively. Furthermore, neither the P-glycoprotein inhibitor verapamil nor Niemann-Pick Cl-Like 1 transporter inhibitor ezetimibe affected the absorption and secretion of imperialine in vitro. The in situ intestinal perfusion study showed that the absorption parameters of imperialine varied in 4 intestinal segments (duodenum, jejunum, ileum and colon) with the highest ones in the colon, where a greater number of non-ionized form of imperialine was present. Conclusion: The intestinal absorptive characteristics of imperialine are closely related to its physicochemical properties. The passive membrane diffusion dominates the intestinal absorption of imperialine.
Adverse Selection Risk Early-Warning of Agricultural Insurance Towards Food Quality Safety — Illustrated by an example of vegetable sites in Shandong province

From the perspective of the agricultural food quality safety, for the adverse selection because of the asymmetric information in agricultural insurance, an analysis approach based on multiclassification discrete choice model is proposed. On the basis of building an agricultural food safety risk evaluation index system, applying the linguistic information processing method, the panel valuation data is aggregated to obtain the integrated evaluation values. An ordered logistic model is put forward, and the calculation analysis steps are given. This research is illustrated by an example of export vegetable sites in Shandong province. The research indicates that the quality safety is the new component of agricultural risk, and the effective risk analysis can be on guard against the adverse selection in agricultural insurance practice. As well the linguistic information can be effectively aggregated with less lost by this method, the classes of agricultural food quality risk are ordinal, and approach will promote the extension and application in agricultural insurance to crop farming.
Epitaxial Growth of Multi-structure SnO_2 by Chemical Vapor Deposition

The nanowire and whisker heterostructures of tin dioxide were fabricated by the chemical vapor deposition technique. It was demonstrated that various structures of tin oxide can be obtained by controlling the thickness of gold layer and the partial pressure of source vapor at growing sites. 12.5 and 25 nm thicknesses are preferable for the epitaxial growth of nanowires and heterostructure through vapor–liquid–solid mechanism, respectively. The tin dioxide whiskers with core-shell structure were fabricated by vapor–solid mechanism. Meanwhile, the influences of various factors on the tin dioxide growth are also discussed.
Texture Evolution and Ultrafine Grain Formation in Cross-Cryo-Rolled Zircaloy-2

The texture and mechanical properties of cross-rolled zircaloy-2 at 77 and 300 K were investigated. Crossrolling at 77 K was performed to impart different thickness reductions of 25% and 50%, while at 300 K with 25%, 50%, 75% and 85% reductions to the sample. EBSD analysis of deformed sample showed that near-basal orientation is not deformed completely after 50% rolling reduction. The activation of prismatic silp, {1122} contraction twin and {1012} extension twin were evident from the deformed microstructure at 77 K. The propensity for activation of basal slip
《中医内科学》“异病同治”用方规律探析

“异病同治”是中医学辨证论治的特色之一,通过对《中医内科学》教材的梳理,将《中医内科学》中异病同治方剂进行归纳和分析,对异病同治的内涵进行剖析,得出异病同治的关键在于证同机同治亦同,异病同治包括异病同证同法同方,亦包括异病同证同法异方,方有主治病机,抓住了病机,方证合宜,就抓住了方剂临床运用的关键。
中医诊治多囊卵巢综合征证型和用药规律文献讨论

目的: 探讨多囊卵巢综合征的中医证治规律。方法: 检索1999年至2013年中国期刊全文数据库(CNKI)收录的中医治疗多囊卵巢综合征的文献,对所选文献中的证型和用药进行统计归类分析。结果: 最终筛选合格文献63篇、证型26个,常见证型有脾肾阳虚、痰瘀互结、肾虚血瘀、肾阴虚、痰湿阻滞、肾虚痰湿共占56.33%。证素有10个,其中虚证占81.88%,主要有阳虚、气虚、阴虚、阴阳两虚和血虚; 实证占18.12%,主要有痰湿、痰瘀、气滞、血瘀,其中痰湿占总证候要素的6.97%。用药148味,按功效归为15类,补虚药使用最多占比39.83%,其次是化痰湿药、活血药、理气药,前4类共占比84.19%。结论: 本病病机复杂,以肾虚为主,痰湿瘀阻为标,肝病是重要发病环节,故补肾调肝兼祛痰化瘀是治疗大法。
试析体质偏性与六淫致病的关系

体质对六淫具有特定的选择性和易感性,六淫致病其发病形式、病变类型、疾病转归都与个体体质因素关系密切。故探讨六淫的概念及其致病机理、体质的相关问题及其形成机制,旨在阐释个体体质偏性对六淫致病的影响,进一步揭示体质偏性与六淫致病的关系,这将为临床上诊治疾病提供一定的参考价值。
“阳明蓄血”致“其人喜忘”探析

从蓄血、阳明两部分论述《伤寒论》“阳明证,其人喜忘者,必有蓄血”的理论,认为蓄血本身可致喜忘,而阳明证是蓄血的重要病因,一旦阳明邪热与蓄血互结,血不得养其心脑,邪热扰其心脑,易导致喜忘,故临床中不可忽视张仲景从瘀辨治喜忘的思路。
一级除盐串联混床系统出水水质超标原因分析

某电厂锅炉补给水除盐系统采用一级除盐串联混床设备,其中一级除盐设备共4列,混床设备共2列,只有当4#一级除盐设备与混床串联运行时系统出水水质合格,其他3列一级除盐设备与混床串联运行时,混床出水电导率超标。为了查明混床出水水质超标的原因,首先对除盐设备、再生工况及树脂性能等进行了排查分析,初步认定阴离子交换器内的树脂被有机物污染是造成系统出水水质超标的主要原因。通过离子交换柱验证试验,证实了1#~3#阴床内的阴离子树脂被有机物污染后导致交换容量降低,运行中阴床泄漏强酸根离子并导致混床出水电导率超标。
珠海西坑尾垃圾填埋场渗滤液处理二期工程设计

珠海西坑尾垃圾填埋场渗滤液处理二期工程采用了中温厌氧(UASB)+膜生化反应系统(MBR,含两级硝化反硝化)+膜深度处理(纳滤/反渗透)主体工艺,浓缩液采用"高级氧化"处理工艺,污泥采用污泥减量化+脱水干化处理工艺。介绍了工程的设计参数并分析了设计特点与流程,处理出水水质能够稳定达到《生活垃圾填埋场污染控制标准》(GB 16889-2008)及广东省《水污染物排放限值》(DB 44/26-2001)的控制出水水质要求。通过优化设计工艺达到低能耗高效率处理垃圾渗滤液并解决了浓缩液和污泥二次污染的问题。
Soil Quality in Relation to Agricultural Production in the North China Plain

Sustainable agricultural production is of vital importance to food supply security. This study aimed to investigate crop yield response to spatial variability of soil quality at a county scale in the North China Plain (NCP) and subsequently derive key soil quality indicators. Soil samples were geo-referenced and taken in 2008 from both surface (0–20 cm) and subsurface (20–40 cm) layers in 132 fields throughout the Fengqiu County, located in the centre of the NCP, for subsequent soil properties’ analyses. Annual crop yields were obtained from the same fields where soil samples were collected. Soil quality was evaluated based on a fuzzy set with 13 soil properties, and its spatial distributions were investigated by integrating geostatistical analysis and geographic information system (GIS) techniques. Soil quality indices were classified into five grades, and their spatial distributions were mapped within the county. The surface soil qualities were about one to two grades higher than the subsurface soil. The quality indices for surface and subsurface soils were positively associated with the annual crop yields, suggesting the importance of both. Soil organic matter, total nitrogen, available P, and available K contributed 50% of the combined weight to the soil quality index and were identified as key indicators of soil quality status in the area in terms of sustainability.
Phase Morphology, Crystallization Behavior and Mechanical Properties of Poly(L-lactide) Toughened with Biodegradable Polyurethane: Effect of Composition and Hard Segment Ratio

Polyester-based biodegradable polyurethane (PU) with different hard segment ratios was selected to modify the impact toughness of poly(L-lactide) (PLLA). The influence of blending composition and hard segment ratio of PU on the phase morphology, crystallization behavior and mechanical properties of PLLA/PU blends has been investigated systematically. The results showed that the PU particles were uniformly dispersed in PLLA matrix at a scale from submicrons to several microns. The glass transition temperature of PU within these blends decreased compared to that of neat PU, but rose slightly with its content and hard segment ratio. The presence of PU retarded the crystallization ability of PLLA, whereas enhanced its elongation at break and impact resistance effectively. As the PU content reaches up to 30 wt%, the phenomenon of brittle-ductile transition occurred, resulting in a rougher fracture surface with the formation of fibril-like structure. Moreover, under the same concentrations, the elongation at break and impact strength of PLLA blends decreased slightly with the increase of hard segment ratio of PU.
内生解淀粉芽孢杆菌CC09

近年来,植物病害的生物防治越来越受到重视,生防细菌是在植物病害防治中应用最广、最有开发潜力的微生物。解淀粉芽孢杆菌(Bacillus amyloliquefaciens)是一种与枯草芽孢杆菌(Bacillus subtilis)亲缘性很高的细菌,不仅能够产生多种抗菌物质,如Iturin等环脂肽类物质,抑制植物病原菌生长,而且具有促进植物生长、诱导植物抗性的活性。因此,该菌被认为是继枯草芽孢杆菌后的又一生防菌,应用潜力巨大。然而,由于该菌代谢产物中抗菌活性物质产量较低,既影响该菌本身的生防效果,又限制该菌抗菌物质的产业化。本刊2014年第1期发表了刘京兰、薛雅蓉、刘常宏等的文章“内生解淀粉芽孢杆菌CC09产Iturin A摇瓶发酵条件优化”[1],作者通过单因子和正交试验设计,比较系统地研究了内生解淀粉芽孢杆菌CC09液体发酵合成抗菌活性物质Iturin A的最佳营养组成以及发酵条件,Iturin A的产量可达到690 mg/L,较优化前的138 mg/L提高了4倍。这一结果不仅为该菌作为生防菌产业化奠定了基础,还为研究该菌环脂肽类物质代谢调控的物质基础提供参考依据,具有重要的意义。
Photocatalytic degradation of the diazo dye naphthol blue black in water using MWCNT/Gd,N,S-TiO_2 nanocomposites under simulated solar light

A simple sol–gel method was employed to prepare gadolinium, nitrogen and sulphur tridoped titania decorated on oxidised multiwalled carbon nanotubes (MWCNT/ Gd,N,S-TiO_2), using titanium (IV) butoxide and thiourea as titanium and nitrogen and sulphur source, respectively. Samples of varying gadolinium loadings (0.2%, 0.6%, 1.0% and 3.0% Gd~(3+)) relative to titania were prepared to investigate the effect of gadolinium loading and the amounts of carbon nanotubes, nitrogen and sulphur were kept constant for all the samples. Furthermore, the prepared nanocomposites were evaluated for the degradation of naphthol blue black (NBB) in water under simulated solar light irradiation. Higher degradation efficiency (95.7%) was recorded for the MWCNT/Gd,N,S-TiO_2 (0.6% Gd) nanocomposites. The higher photocatalytic activity is attributed to the combined effect of improved visible light absorption and charge separation due to the synergistic effect of Gd, MWCNTs, N, S and TiO_2. Total organic carbon (TOC) analysis revealed a higher degree of complete mineralisation of naphthol blue black (78.0% TOC removal) which minimises the possible formation of toxic degradation by-products such as the aromatic amines. The MWCNT/Gd,N,S-TiO_2 (0.6% Gd) was fairly stable and could be re-used for five times, reaching a maximum degradation efficiency of 91.8% after the five cycles.
Interannual and Decadal Variations of Surface Solar Radiation over East China in the First Half of the 20th Century

Variability and long-term trends of sunshine duration (SSD) and total cloud cover (TCC) were studied based on surface observations from 10 meteorological stations over East China in the first half of the 20th century. The correlation coefficients between SSD and diurnal temperature range (DTR), as well as TCC, were analyzed. SSD experienced a significant increasing trend (0.16 h d~(-1) per decade) from 1908 to 1936, and the maximum brightening was in autumn (0.33 h d~(-1) per decade). The good agreement between the variability of SSD and DTR, supported by the correlation coefficient between them of 0.72, implies that the SSD measurements were reliable. TCC showed a decreasing trend (–0.93% per decade) and was significantly inversely related to SSD (–0.74), indicating the variation of SSD was attributable to changes in cloud cover. The result was obviously different to that since the 1960s, when clouds could not account for the decadal trend of surface solar radiation in China.
An Economical Approach to Flow-Adaptive Moderation of Spurious Ensemble Correlations and Its Application in the Proper Orthogonal Decomposition-Based Ensemble Four Dimensional Variational Assimilation Method

The purpose of this study is to describe an economical approach to an existing adaptive localization technique and its implementation in the proper orthogonal decomposition-based ensemble four-dimensional variational assimilation method (PODEn4DVar). Owing to the applications of the sparse processing and EOF decomposition techniques, the computational costs of this proposed sparse flow-adaptive moderation (SFAM) localization scheme are significantly reduced. The effectiveness of PODEn4DVar with SFAM localization is demonstrated by using the Lorenz-96 model in comparison with the Smoothed ENsemble Correlations Raised to a Power (SENCORP) and static localization schemes, separately. The performance of PODEn4DVar with SFAM localization shows a moderate improvement over the schemes with SENCORP and static localization, with low computational costs under the imperfect model.
All-Sky Direct Radiative Effects of Urban Aerosols in Beijing and Shanghai, China

Aerosol particles can directly alter the radiation balance by scattering and absorbing incident solar radiation, thus decreasing the amount of light reaching the surface and increasing the fraction of diffuse radiation— the so-called ‘aerosol direct radiative effect’. Using the Moderate Resolution Imaging Spectroradiometer aerosol products, the aerosol direct radiative effects under all-sky conditions in Beijing and Shanghai in 2007 were explored in this study. The total shortwave radiation was calculated using the Fu-Liou radiative transfer model, with the influence of clouds taken into account through sunshine-duration data, and the diffuse radiation was calculated with radiation decomposition models. Good correlation between measured and calculated total radiation was obtained at both cities, with an R greater than 0.9, and thus this calculation method was adopted to derive aerosol direct radiative effects. The presence of aerosols caused the mean total and diffuse solar radiation reaching the surface to change by –19.9% and +27.4% in Beijing, respectively, and by –18.4% and +6.5% in Shanghai. It was also found that, despite the strong negative correlation between aerosol optical depth and total radiation change, the diffuse radiation changes were determined predominantly by clouds. The effects of such changes induced by aerosols on plant productivity should be further studied.
心脏异物损伤误诊急性冠脉综合征一例

心脏异物比较少见,大多为外伤时异物通过胸壁进入心脏所致[1-2]。闭合性心脏外伤表现多样,缺乏特征性,但有隐蔽性、迟发性的特点,易漏诊和误诊。本文报道一例心脏异物损伤误诊急性冠脉综合征一例。
胸腔镜辅助下应用“捆绑式外固定”治疗肋骨骨折错位及浮动胸壁体会

肋骨骨折是胸部外伤中的常见疾病,多数可采用保守治疗,尤其对于多根、多段肋骨骨折,因胸壁变得极其不稳定,可引发连枷胸,严重者将导致严重的呼吸、循环功能障碍,此时则需要应用外科处置及手术干预。目前,针对完全断裂肋骨骨折的治疗主要采用人工复位与小钢板内固定相结合的方法,本文选取舟山市普陀医院自2006年5月至2013年12月收治肋骨骨折错位及反常呼吸的患者资料,采用一种新的手术方法:即“肋骨骨折捆绑式外固定”,旨在探讨肋骨骨折外科治疗的新方法及实用性。
肺动静脉瘘致心搏骤停后超长心肺复苏成功一例

肺动静脉瘘(pulmonary arterio-venous fistula,PAVF)或称肺动静脉畸形(pulmonary arteriovenous malformations,PAVM)是一种肺内血管畸形,多发生在肺动静脉之间。由于肺动脉血液未经毛细血管氧合,致血氧饱和度降低,引起一系列临床症状,如心慌气短、全身无力、发绀、杵状指(趾),血色素升高以致心肺功能受损等。近期嘉兴市第一医院重症医学科收治一例猝死后经超长心肺复苏成功,并最终明确为肺动静脉瘘的患者,现报道如下。
院外心脏骤停复苏成功一例

据报道,2007年北京市每150人中仅有1人掌握急救技术,这与发达国家如美国要求的1/3以上公民学会院前急救技术的比例相差甚远。北京急救中心调查显示,大学生对于止血、包扎、晕倒处理、火灾处理的正确知晓率分别为58.66%、45.51%、54.28%、21.09%, 这也充分显示了我国公众的急救知识掌握情况不佳,所以对于公众的急救知识的普及急需加强。
Galen静脉畸形的血管内栓塞治疗

Galen静脉畸形(vein of Galen aneurysm malformation)是起源于脉络丛静脉回流系统的血管畸形。在胚胎发育的第6~11周,胚胎Markowski中间静脉发育异常,形成一种特殊的血管畸形,其有单个中间引流静脉,同时在静脉壁上有多个动静脉瘘。因为高速血流的冲击,静脉呈瘤样扩张,外形很像动脉瘤,所以在1946年Jaeger将其命名为Galen静脉动脉瘤样血管畸形。患者大多年龄小,病情复杂,在血管内治疗引入之前,其治疗难度大,病死率高。广州军区武汉总医院神经外科1995年1月至2013年12月收治了192例6岁以下的中枢神经系统血管畸形,其中有6例Galen静脉畸形,治疗效果满意,现报道如下。
BOLD-fMRI成像技术在脑梗死后脑功能重组及运动功能康复机制中的应用

1血氧水平依赖(blood oxygenation level dependent,BOLD)成像机制及原理狭义的脑功能磁共振检查(fMRI)仅指血氧水平依赖-功能磁共振(blood oxygenation level dependent- functional MRI,BOLD-fMRI),其成像机制由Ogawa S等首次发现并提出,它是一种以脱氧合血红蛋白的磁敏感效应为基础的磁共振成像技术。
被动运动关节类手法联合温针灸、微波治疗肩周炎远期疗效分析

肩周炎是康复医学科常见病、多发病,属于中医痹证范畴,又称为“肩凝证”、“五十肩”、“冻结肩”、“漏肩风”等。因肩关节退变、外伤、劳损、受寒等因素使肩关节周围组织充血、水肿、渗出、粘连而致肩周肌肉、肌腱、滑囊和关节囊的无菌性炎性反应,以肩部疼痛,肩关节功能障碍,肌肉萎缩为主要临床症状。综合疗法治疗肩周炎疗效肯定,但未见临床远期疗效追踪观察报道,我科采用被动运动关节类手法联合温针灸、微波治疗肩周炎远期疗效显著,现将2012年1月-2013年1月我科收治的86例肩周炎患者的临床资料回顾性分析如下。
中国脑性瘫痪康复指南(2015):第一部分

指南制定背景本指南参考欧洲、美国、日本等国家脑瘫康复指南及2014年12月以前国内外发表的医学文献,综合我国儿童康复医学专家的共同意见而形成。本指南由卫生部卫生行业科研专项(项目编号:201002006)资助,中国康复医学会儿童康复专业委员会、中国残疾人康复协会小儿脑性瘫痪康复专业委员会对本指南全面负责,拥有所有权及解释权。
CT引导射频消融治疗肝癌

经皮肝癌射频消融治疗的影像引导方法包括超声、CT、MRI、DSA等。超声引导是最为常用的方法。DSA透视下引导方法用于已经接受经动脉碘化油栓塞的肿瘤,尤其是那些具有旋转扫描再成像功能的DSA机。MRI引导因其特殊的设备要求在我国很少使用。CT具有较强的密度分辨力和空间分辨力,结合增强扫描及三维重建可清晰显示病变大小、形态及与附近结构的解剖关系,为适形消融治疗提供了可靠信息。尤其对于一些深在、隐匿、靠近膈顶的小病灶,以及B超难以观察到的病变,采用CT引导有更多的优越性。同时,现代CT还常具有实时透视功能,克服了常规CT由于呼吸运动造成病灶移位的影响,大大提高了穿刺准确性并节省了操作时间。CT的最大缺点是具有一定的放射辐射,而通过设计合适的扫描方式,将会大大减少辐射剂量。因此CT适合各种消融技术的导向,并被广泛的应用于临床。
山东省临沂市烟田耕作层土壤重金属含量

采集山东省临沂市的100个典型烟田耕作层土壤样品,分析了其As、Cd、Cr、Hg和Pb全量,并与相应的国家限制值进行对比。结果表明:①临沂市典型烟田土壤中As、Cd、Cr、 Hg和Pb含量分别为0.20~30.52、0.01~0.38、4.38~128.00、0~0.36和4.99 ~ 70.80 mg/kg,均低于相应的国家标准限制值,尚未发生重金属污染现象;②3个pH级别中,As、Cd、Cr、Hg和Pb含量与对应的限制值的比值,最大值分别为76.3%、96.7%、85.3%、90.0%和88.5%,说明临沂市烟田面临着潜在的重金属污染威胁,必须继续严格控制烟田的重金属外源以确保烟田土壤质量安全。
Using heterogeneous patent network features to rank and discover influential inventors

Most classic network entity sorting algorithms are implemented in a homogeneous network, and they are not appli? cable to a heterogeneous network. Registered patent history data denotes the innovations and the achievements in different re? search fields. In this paper, we present an iteration algorithm called inventor-ranking, to sort the influences of patent inventors in heterogeneous networks constructed based on their patent data. This approach is a flexible rule-based method, making full use of the features of network topology. We sort the inventors and patents by a set of rules, and the algorithm iterates continuously until it meets a certain convergence condition. We also give a detailed analysis of influential inventor's interesting topics using a latent Dirichlet allocation (LDA) model. Compared with the traditional methods such as PageRank, our approach takes full ad? vantage of the information in the heterogeneous network, including the relationship between inventors and the relationship be? tween the inventor and the patent. Experimental results show that our method can effectively identify the inventors with high influence in patent data, and that it converges faster than PageRank.
Reconfiguring phosphorylation signaling by genetic polymorphisms affects cancer susceptibility

Large-scale sequencing has characterized an enormous number of genetic variations (GVs), and the functional analysis of GVs is fundamental to understanding differences in disease susceptibility and therapeutic response among and within populations. Using a combination of a sequence-based predictor with known phosphorylation and protein-protein interaction information, we computationally detected 9606 potential phosSNPs (phosphorylation-related single nucleotide polymorphisms), including 720 known, disease-associated SNPs that dramatically modify the human phosSNP-associated kinase-substrate network. Further analyses demonstrated that the proteins in the network are heavily associated in various signaling and cancer pathways, while cancer genes and drug targets are significantly enriched. We re-constructed four population-specific kinase-substrate networks and found that several inherited disease or cancer genes, such as IRS1, RAF1, and EGFR, were differentially regulated by phosSNPs. Thus, phosSNPs may influence disease susceptibility and be involved in cancer development by reconfiguring phosphorylation networks in different populations. Moreover, by systematically characterizing potential phosphorylation-related cancer mutations (phosCMs) in 12 types of cancers, we observed that both types of GVs preferentially occur in the known cancer genes, while a considerable number of phosphorylated proteins, especially those over-representing cancer genes, contain both phosSNPs and phosCMs. Furthermore, it was observed that phosSNPs were significantly enriched in amplification genes identified from breast cancers and tyrosine kinase circuits of lung cancers. Taken together, these results should prove helpful for further elucidation of the functional impacts of disease-associated SNPs.
Ab initio Predictions of Structural and Thermodynamic Properties of Zr_2AIC Under High Pressure and High Temperature

The structural and thermodynamic properties of Zr_2AIC at high pressure and high temperature are investigated by first principles density functional theory method. The calculated lattice parameters of Zr_2AlC are in good agreement with the available theoretical data. The pressure dependences of the elastic constants, bulk modulus, shear modulus, Young's modulus, and Vickers hardness of Zr_2AlC are successfully obtained. The elastic anisotropy is examined through the computation of the direction dependence of Young's modulus. By using the quasiharmonic Debye model, the thermodynamic properties including the Debye temperature, heat capacity, volume thermal expansion coefficient, and Gruneisen parameter at high pressure and temperature are predicted for the first time.
影像引导射频消融治疗肺部肿瘤专家共识(2015年版)

编者按:肺癌是最常见的恶性肿瘤之一,我国每年大约有60万人死于肺癌,因此愈发引起关注。由中华医学会胸心血管外科学会肺癌学组组织,首都医科大学宣武医院胸外科刘宝东起草,支修益组织国内相关专家在2014年10月至2014年11月通过讨论、电子邮件等形式,反复征求参审专家的意见,达成了影像引导射频消融治疗肺部肿瘤的专家共识现已公布,旨在规范操作技术、进行疗效评估、减少并发症和提高治疗效果。
孤独症儿童多模态功能MRI研究进展

孤独症(autism spectrum disorder,ASD)是一种以社会交往障碍、沟通障碍和局限、刻板、重复行为为主要特征的精神发育谱系障碍。按照临床诊断标准,ASD 可以包含孤独性障碍(典型ASD,又称为婴儿ASD、儿童ASD或Kanner ASD)、儿童瓦解性障碍、待分类的广泛性发育障碍、Asperger 障碍(又称为Asperger 综合征)等多种疾病。 ASD 儿童目前缺乏早期、快速、方便可行的诊断,导致很多儿童错过ASD 有效的早期干预期,北京目前孤独症康复机构ASD 儿童数量远超过负荷,年龄为3~6岁,即大部分家长发现孩子无法正常上幼儿园、上小学才开始接受行为学治疗,ASD 亟需早期、快速、方便可行的诊断方法。本文对 ASD 儿童多模态功能MRI(fMRI)研究进展作一综述。
几个专业词汇的界定、浅析及其相关说明

近年来,笔者参与的几个项目都处于总结阶段。每一项目都有多人参加,为了避免文件用词发生歧义,笔者就有关的专业词汇做了一些简短界定和说明。写成以后,业内同仁认为虽选词不多,但对草业的深化理解不无帮助,建议公开发表,以利大家共同推进草业学科的发展。
Bayesian optimal design of step stress accelerated degradation testing

This study presents a Bayesian methodology for designing step stress accelerated degradation testing (SSADT) and its application to batteries. First, the simulation-based Bayesian design framework for SSADT is presented. Then, by considering historical data, specific optimal objectives oriented Kullback-Leibler (KL) divergence is established. A numerical example is discussed to illustrate the design approach. It is assumed that the degradation model (or process) follows a drift Brownian motion; the acceleration model follows Arrhenius equation; and the corresponding parameters follow normal and Gamma prior distributions. Using the Markov Chain Monte Carlo (MCMC) method and WinBUGS software, the comparison shows that KL divergence is better than quadratic loss for optimal criteria. Further, the effect of simulation outliers on the optimization plan is analyzed and the preferred surface fitting algorithm is chosen. At the end of the paper, a NASA lithium-ion battery dataset is used as historical information and the KL divergence oriented Bayesian design is compared with maximum likelihood theory oriented locally optimal design. The results show that the proposed method can provide a much better testing plan for this engineering application.
Combined algorithm of acquisition and anti-jamming based on SFT

A communication and navigation receiver is required to remove hostile jamming signals and synchronize receiving signals effectively especially for satellite communication and navigation whose resources are becoming more and more limited. This paper proposes a novel signal receiving method by combining the processes of anti-jamming and synchronization to reduce the overall computational complexity at the expense of slightly affecting the detection probability, which is analyzed in detail by derivations. Furthermore, this paper introduces sparse Fourier transformation (SFT) into the proposed algorithm to replace fast Fourier transformation (FFT) so as to further reduce the calculation time especially in large frequency offset environments.