mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Feedback Learning Based Dead Write Termination for Energy Efficient STT-RAM Caches

Spin-torque transfer RAM (STT-RAM) is a promising candidate to replace SRAM for larger Last level cache (LLC). However, it has long write latency and high write energy which diminish the benefit of adopting STT-RAM caches. A common observation for LLC is that a large number of cache blocks have never been referenced again before they are evicted. The write operations for these blocks, which we call dead writes, can be eliminated without incurring subsequent cache misses. To address this issue, a quantitative scheme called Feedback learning based dead write termination (FLDWT) is proposed to improve energy efficiency and performance of STT-RAM based LLC. FLDWT dynamically learns the block access behavior by using data reuse distance and data access frequency, and then classifies the blocks into dead blocks and live blocks. FLDWT terminates dead write block requests and improves the estimation accuracy via feedback information. Compared with STT-RAM baseline in the lastlevel caches, experimental results show that our scheme achieves energy reduction by 44.6% and performance improvement by 12% on average with negligible overhead.
A Delay-Aware Congestion Control Protocol for Wireless Sensor Networks

In wireless sensor networks, congestion leads to buffer overflowing, and increases delay. The traditional solutions use rate adjustment to mitigate congestion, thus increasing the delay. A Delay-aware congestion control protocol (DACC) was presented to mitigate congestion and decrease delay. In order to improve the accuracy of the existing congestion detection model which is based on the buffer occupancy of a single node, DACC presents a new model considering both the real-time buffer occupancy and the average transmission time of packets. DACC uses the untapped bits in the IEEE 802.11 Distributed coordination function (DCF) frames header to carry congestion information. During the congestion alleviation period, DACC presents a channel occupancy mechanism which is based on the real-time buffer occupancy for the purpose of decreasing delay and preventing packet loss. Simulation results indicate that in terms of delay, packet delivery ratio, collision and buffer load, DACC has comparative advantages than those of 802.11 DCF, Priority-based congestion control protocol (PCCP) and Decoupling congestion control and fairness (DCCF).
基于传递路径分析的关门声贡献量研究

为了改善汽车关门声品质,研究不同部件对汽车关门噪声的贡献量,采用了传递路径分析(TPA)方法。根据TPA的基础理论,车门和车身发生碰撞的部位均为激励源,由于激励源为环状,进行了离散化处理,建立了汽车关门的传递路径模型,并对某款车进行了关门噪声试验。通过试验验证了离散化处理和所建模型的准确性,同时得到车门、车身和门锁对关门噪声总体以及不同频率下的贡献量。根据试验结果,车门的噪声贡献主要集中在中频和高频,车身主要是低频和中频的噪声贡献,而门锁在低、中、高频都具有较大贡献量。
Amorphous Cobalt Boron Alloy@Graphene Oxide Nanocomposites for Pseudocapacitor Applications

Amorphous Co–B alloy nanoparticles grown on graphene sheets were synthesized via a chemical reduction approach and successfully used for an application as a pseudocapacitor. This study aims to improve the capacity and cycling stability of amorphous Co–B alloy nanoparticles grown on conductive graphene sheets. The products were characterized by X-ray powder diffraction, scanning electron microscopy, and transmission electron microscopy. As electrode materials for pseudocapacitors, the amorphous Co–B alloy grown on graphene oxide(Co–B@GO)exhibits a high specific capacitance of 460 F g~(–1), which is nearly 1.5 times greater than that of bare Co–B nanoparticles at 1 A g~(–1). The specific capacitance preserved 84% of the initial capacitance even after 1000 cycles at a scan rate of 10 m V~(–1), suggesting its promising potential as pseudocapacitor materials.
Photovoltaic devices employing ternary PbS_xTe_(1-x) nanocrystals

Colloidal quantum dots(CQDs), especially lead chalcogenide CQDs, are regarded as promising materials for the next generation solar cells, due to their large absorption coefficient, excellent charge transport, and multiple exciton generation effect. We successfully synthesized highly-crystalline, monodispersed, well-alloyed PbS_xTe_(1-x)nanocrystals via a one-pot, hot injection reaction method. Energy-filtered transmission electron microscopy suggested that the S and Te anions were uniformly distributed in the alloy nanoparticles. The photovoltaic performance of CQD solar cells based on ternary PbS_xTe_(1-x)was reported for the first time. The photovoltaic devices using PbS_xTe_(1-x)were more efficient than either the pure PbS or the PbTe based devices. In addition, the PbS_xTe_(1-x)based devices showed a significantly improved stability than that of the PbTe based devices.
Tailoring the photophysical and photovoltaic properties of boron-difluorodipyrromethene dimers

Five boron-difluorodipyrromethene (BODIPY) dimers have been designed and synthesized successfully via acid-catalysed condensation and Pd-catalysed cross-coupling reactions. The structural modification, including verifying the structures of the π-bridges, altering the positions the bridges link (meso- or β-positions), and regulating the molecular planarity, can modulate the photophysical properties and the aggregation behaviors of the five dimers efficiently. Solution-processed organic solar cells were fabricated to evaluate the photovoltaic properties of these molecules further either as acceptors or donors. When using as nonfullerene acceptor and blended with the polymer donor of PTB7, an opencircuit voltaic (V_(oc)) of 1.12 and 1.08 V was achieved from the thiophene and benzodithiophene bridged BODIPY dimers, respectively. This C_(oc) is among the top values achieved from the non-fullerene organic solar cells so far.
Fabrication of sulfonated mesoporous carbon by evaporation induced self-assembly/carbonization approach and its supercapacitive properties

Synthesis of functionalized mesoporous carbon by an easy-accessed method is of great importance towards its practical applications. Herein, an evaporation induced self-assembly/carbonization (EISAC) method was developed and applied to the synthesis of sulfonic acid group functionalized mesoporous carbon (SMC). The final mesoporous carbon obtained by EISAC method possesses wormlike mesoporous structure, uniform pore size (3.6 nm), large surface area of 735 m~2/g, graphitic pore walls and rich sulfonic acid group. Moreover, the resultant mesoporous carbon achieves a superior electrochemical capacitive performances (216 F/g) to phenolic resin derived mesoporous carbon (OMC, 152 F/g) and commercial activated carbon (AC, 119 F/g).
温阳豁痰熄风法治疗早发性癫痫性脑病1例

本例患儿是类细胞周期蛋白依赖性蛋白激酶5基因(CDKL5)变异导致癫痫发作,属于早发性癫痫性脑病的范畴。本病抗癫痫药物控制不佳,并且具有精神运动发育落后等表现。根据患儿的病理性体质以及症状体征辨证为脾肾阳虚,温煦乏力,痰浊日久不化之阴痫。治以温阳豁痰、熄风止痉,以达标本兼施之目的,临床短期疗效显著。
异质时空数据插值方法研究

插值建模旨在利用已有采样数据对空间/时空缺失数据或未采样数据进行估计,生成高精度空间曲面或时空网格,精确表达时空过程的空间/时空分布模式。然而,现有插值方法没有充分考虑时空数据的异质性和多元协变量的影响,导致插值精度很难满足要求。鉴于此, 本论文以异质时空数据为主要研究对象,深入研究了顾及多元协变量影响的高精度空间/时空插值方法,具体包括。
采用安捷伦5977B GC- MS测定土壤中硝基苯类化合物含量

本文采用安捷伦7890B_5977B GC-MS测定土壤样品中的硝基苯类化合物含量.样品前处理方法以及仪器分析方法参考《GC-MS测定半挥发性有机物》(EPA method 8270D)和土壤样品前处理标准HJ 783—2016规定的样品前处理要求和仪器分析条件.分别采用两种加压快速溶剂萃取的提取方法,结合弗罗里硅土净化法,对土壤样品进行提取与净化,建立了详细的前处理步骤并对处理过程中的要点进行描述.此方法成功应用于土壤中14种硝基苯类化合物的分析测定,样品加标回收率达到了73%—104% (标准要求40%— 150%),仪器最低检出限为1.3—2.3 μg·kg~(-1),方法检出限为1.4—2.4 μg·kg~(-1).
Designing healthy communities: Testing the walkability model

Research from multiple domains has provided insights into how neighborhood design can be improved to have a more favorable effect on physical activity, a concept known as walkability. The relevant research findings/hypotheses have been integrated into a Walkability Framework, which organizes the design elements into nine walkability categories. The purpose of this study was to test whether this conceptual framework can be used as a model to measure the interactions between the built environment and physical activity. We explored correlations between the walkability categories and physical activity reported through a survey of residents of Tucson, Arizona (n=486). The results include significant correlations between the walkability categories and physical activity as well as between the walkability categories and the two motivations for walking (recreation and transportation). To our knowledge, this is the first study that reports links between walkability and walking for recreation. Additionally, the use of the Walkability Framework allowed us to identify the walkability categories most strongly correlated with the two motivations for walking. The results of this study support the use of the Walkability Framework as a model to measure the built environment in relation to its ability to promote physical activity.
Graphene: Nanostructure engineering and applications

Graphene has attracted extensive research interest in recent years because of its fascinating physical properties and its potential for various applications. The band structure or electronic properties of graphene are very sensitive to its geometry, size, and edge structures, especially when the size of graphene is below the quantum confinement limit. Graphene nanoribbons (GNRs) can be used as a model system to investigate such structure-sensitive parameters. In this review, we examine the fabrication of GNRs via both top-down and bottom-up approaches. The edge-related electronic and transport properties of GNRs are also discussed.
The cold pool of the Bay of Bengal and its association with the break phase of the Indian summer monsoon

During the summer monsoon season, strong coastal upwelling occurs along the southwest coast of India and at the southern tip of India, which cools the surface temperature of the waters around these regions.The summer monsoon current carries the upwelled cold waters into the Bay of Bengal and forms the 'cold pool of the Bay of Bengal: with its core south of Sri Lanka and over the south-central Bay of Bengal. The present study focuses on the intrusion of these cold waters into the south of the Bay of Bengal, its interannual variability, and its association with the surface wind during the break phase of the summer monsoon, when strong westerly surface winds flow south of 10°N. The authors hypothesize that the enhanced cooling in the cold pool region during monsoon spells is associated with the strong westerly wind stress there during the break spells of the monsoon. Seven cases of long break monsoon spells that occurred during the nine years from 2001 to 2009 are analyzed, and the results confirm our hypothesis.
A novel phenotypic assay of hepatitis B virus polymerase with extensive site-specific mutagenesis

A common reason for drug failure during long-term treatment of chronic hepatitis B with nucleot(s)ide analogues (NUCs) is the emergence of drug resistance(Das et al., 2001). Most primary NUCs-resistant mutations identified in clinical samples have been limited to a minority of amino acids (usually less than three kinds) that replace the wild type amino acid at a single site (Kirishima et al., 2002). However, each site should, theoretically, have the same opportunity to be mutated to any of the 19 amino acids other than that of the wild type during the DNA synthesis catalyzed by the error-prone viral polymerase (Bartholomeusz et al., 2004). Therefore, precisely how these undiscovered possible mutations influence the viral phenotype is an interesting research question. To address this issue, Baldick et al. constructed a comprehensive panel of clones containing every possible amino acid at the three primary amino acid positions related to entecavir resistance (rtT184, rtS202, or rtM250) in the lamivudine(LAM)-resistant hepatitis B virus (HBV) background(rtM204V + rtL180M) to determine the phenotypic impact of these substitutions (Baldick et al., 2008). Although extensive mutagenesis analysis is very useful, this kind of assay is usually difficult to conduct. The construction of mutated plasmids would be laborious if there are a large amount of mutants need to be tested. In addition, the transfection step can be a source of variation, and the plasmid DNA transfected into cells, if not completely eliminated during the purification step, will interfere with the detection of HBV DNA replicative intermediates. Herein, we report an alternative method for conducting an extensive mutagenesis phenotype assay of HBV polymerase. This method is based on our previously developed polymerase trans-complement strategy (Luo et al., 2016). Using the well-known LAM-resistant mutation rtM204 site as a target, we have demonstrated the feasibility of this method.
Characterization of viral entry and infection of quantum dot-labeled grass carp reovirus

Reoviruses are non-enveloped icosahedral virions with an outer capsid surrounding their cores, which harbor the 10-12 segmented double-stranded RNA (dsRNA) genome. To date, there are 15 proposed genera in the family Reoviridae (King et al., 2012),including Aquareovirus. Generally, aquareoviruses are of low pathogenicity in aquaculture. However, grass carp reovirus (GCRV) is a highly pathogenic agent that is capable of causing serious hemorrhagic disease in aquatic animals (Fang et al., 1989; Rangel et al., 1999). Thus, GCRV serves as an ideal model for studying the infection and pathogenesis of aquareoviruses.
基于血气分析角度的黄连解毒汤对动脉粥样硬化大鼠的影响

目的探讨黄连解毒汤(Huanglian Jiedu Decoction,HJD)对动脉粥样硬化大鼠血气指标的影响。方法雄性SD大鼠,随机分成正常对照组、模型组、洛伐他丁组及黄连解毒汤低、中、高3个剂量组,每组10只。除正常对照组喂普通饲料外,其余喂以高脂饲料,同时定期注射维生素D_3,造模8周,从第3周开始每天灌胃给药1次。造模结束后于腹主动脉取血,测定相关指标。结果血脂结果显示:与正常对照组比较,模型组的总胆固醇(TC)、甘油三酯(TG)、低密度脂胆固醇(LDL)显著上升,高密度脂胆固醇(HDL)显著下降(P<0.05);给药后,各组均可显著降低LDL、TG指标,阳性对照组和HJD低剂量组可显著降低TC指标,且高剂量组可显著升高HDL指标(P <0.05)。血气分析结果显示:与正常对照组比较,造模后,动脉氧分压(pO_2)极显著下降(P <0.001),二氧化碳分压(pCO_2)、二氧化碳总量(pCO_2 (T))显著上升(P<0.05);给药后,除黄连解毒汤高剂量组,其余各组均可显著升高pO_2(P<0.05),但对pCO_2、pC02(T)无显著性影响(P>0.05)。各组pH值均无显著差异(P>0.05)。结论黄连解毒汤对动脉粥样硬化大鼠可起到一定干预作用,推测其作用机制为改善大鼠的氧分压。
从阴阳自和角度论肝脏脂质代谢与细胞自噬的关系

自噬是机体内利用溶酶体降解自身受损细胞组分的过程,有利于机体内物质平衡和内环境稳态。在肝脏脂质代谢过程中,一方面细胞自噬的上调促进脂滴的分解,一方面自噬的下调则促进脂质的聚积,同时肝脏细胞脂质聚积也会对自噬产生负向调节。自噬对于肝脏脂质代谢的正向或者负向调节,从微观调控着体内的脂质稳态。阴阳自和是阴阳二者生理状态下自动维持平衡的能力,细胞自噬也是微环境的动态平衡。笔者试从中医阴阳自和角度论细胞自噬对于肝脏脂质代谢的影响,阐述从细胞自噬与阴阳自和理论指导肝脏脂质代谢紊乱治疗的现代意义。
止痛健骨方对兔膝骨关节炎软骨MMP-1的影响及与MRI分级的相关性分析

目的观察止痛健骨方对兔膝骨关节炎软骨MMP-1的影响及与MRI分级的相关性分析。方法将90只白兔随机分为正常对照组、模型对照组、阳性药物组、止痛健骨低剂量组、止痛健骨高剂量组,每组各18只,采用木瓜蛋白酶制备兔膝骨关节炎模型,止痛健骨低剂量组、止痛健骨高剂量组分别给与止痛健骨方低剂量、高剂量药物灌胃,阳性药物组给与盐酸氨基葡萄糖片灌胃,0.0672g/kg,正常对照组和模型对照组则给与生理盐水灌胃。在模型验证、实验灌胃第4周、第8周三个时间点,各组随机选择6只白兔,进行膝关节MRI扫描,并检测软骨MMP-1表达水平,进行对比比较。结果在实验干预前、实验干预第4周、第8周,与正常对照组比较,模型对照组、阳性药物组、止痛健骨低剂量组、止痛健骨高剂量组软骨MMP-1表达、MRI软骨分级均上升,差异有统计学意义(P<0.05)。与模型对照组比较,阳性药物组、止痛健骨低剂量组、止痛健骨高剂量组第4周、第8周MMP-1表达下降,差异有统计学意义(P<0.05)。采用等级Spearman等级相关分析发现软骨MMP-1表达增加,对应软骨MRI分级也上升,两者呈直线正相关(r = 0.815,P =0.000)。结论止痛健骨方能降低兔KOA模型关节软骨MMP-1表达,降低软骨MRI分级,且两者成正向直线相关,这可能为其治疗KOA的作用机理。
独立计量区(DMA)精细化管理研究和实践

作为供水管网漏损控制的重要技术手段,越来越多的国内供水企业开展了DMA建设工作,但由于缺乏DMA建设和运行技术管理规范,导致基于DMA的漏损控制难以取得预期的理想效果。北京市自来水集团近年来开展了DMA建设和运行全流程技术管理研究,介绍了DMA建设的主要内容及相关技术标准,阐述了DMA运行的主要内容、漏损控制量化考核指标及其计算方法,并对下一步研究思路和方向进行了展望。
Single sub-microwire solar cells based on the CdS-Cu2S and CdS-ZnS core-shell heterostructures

CdS sub-microwires with diameter of 200 nm were synthesized by a physical evaporation, Cu_2S and ZnS were decorated on CdS sub-microwires as shells by immersing the CdS core into Cu~+, Zn~(2+) and S~(2-) solutions, respectively. The single core-shell sub-microwires were separated individually on the regular Au pattern by the photolithography technique, and then two ends of the sub-microwires were well contacted with Au electrodes by using the electron beam lithography. The photovoltaic efficiencies of 4.54% and 1.40% were achieved by CdS-Cu_2S and CdS-ZnS core-shell heterostructure under AM 1.5 G illumination, respectively.
Preparation of three-dimensional graphene foam for high performance supercapacitors

Supercapacitor is a new type of energy-storage device, and has been attracted widely attentions. As a two dimensional (2D) nanomaterials, graphene is considered to be a promising material of supercapacitor because of its excellent properties involving high electrical conductivity and large surface area. In this paper, the large-scale graphene is successfully fabricated via environmental-friendly electrochemical exfoliation of graphite, and then, the three dimensional (3D) graphene foam is prepared by using nickel foam as template and FeCl_3/HCl solution as etchant. Compared with the regular 2D graphene paper, the 3D graphene foam electrode shows better electrochemical performance, and exhibits the largest specific capacitance of approximately 128 F/g at the current density of 1 A/g in 6 M KOH electrolyte. It is expected that the 3D graphene foam will have a potential application in the supercapacitors.
非典型抗肾小球基底膜病合并IgA肾病一例

患者,女,31岁,因“尿检异常伴肌酐升高半个月”入院。半个月前因“子宫肌瘤”在当地医院住院,期间查尿常规示隐血3+,蛋白3+,红细胞计数1.0891×10~9个/L,24h尿蛋白量4.0 g;肾功能示肌酐114 μmol/L,于2016年7月14日行肾穿刺术。术后多次复查肌酐提示进行性升高,7月19日肌酐226 μmol/L。为进一步诊治转入浙江省人民医院。查体:血压(BP) 117/79 mmHg,心肺腹无特殊,双下肢无凹陷性水肿。辅助检查:抗核抗体阳性(1:100),抗线粒体抗体阳性;中性粒细胞胞质抗体(ANCA)阴性,抗肾小球基底膜(GBM)抗体阴性(19.7 RU/ml)(正常值0~ 20 RU/ml);尿常规示蛋白3+,隐血3+,红细胞计数7.728× 108个/L;血常规示白细胞3.94×10~9/L,血红蛋白110.0 g/L,血小板184xl0~9/L,免疫球蛋白+;IgG 11.5 g/L(正常范围8.0 ~ 14.5 g/L), IgA 2.05 g/L (正常范围1.14 ~ 2.26 g/L), IgM 1.63 g/L(正常范围0.77 ~ 1.93 g/L),C_3 0.87 g/L(正常范围0.8~1.5),C_40.17g/L(正常范围0.2~0.6g/L);白蛋白32.1 g/L(正常范围35~55 g/L),尿素8.14mmol/L,肌酐247.9 μmol/L,尿酸373 μmol/L;血沉17.0 mm/h(正常范围0~20 mm/h);双肾B超:101 mm×42 mm(右),115 mm×45 mm(左)。肾组织病理检查:光镜:33个肾小球,2个球性硬化,8个细胞性、1个细胞纤维性、4个节段细胞性新月体形成,5个球包曼囊壁有断裂,4个球血管袢节段纤维素样坏死,8个球血管袢缺血皱缩,13个球外周袢与囊壁粘连,局灶囊壁增厚分层;间质慢性病变轻度(约15%)。免疫荧光:IgA(4+)、IgM(3+)、C_3(3+)弥漫球性系膜区颗粒状沉积;1gG(4+)、1gG_1(3+)、IgG_4(2+)弥漫球性血管袢线状沉积;IV型胶原al、a3、a5均连续性阳性;κ轻链(4+),λ轻链(3+),呈弥漫球性系膜区、血管袢颗粒状、线状沉积。电镜:足突部分融合,系膜区可见少量电子致密物沉积。见图1。诊断:非典型抗GBM病伴IgA肾病伴新月体形成(41.9%)。患者血浆置换5次,甲泼尼龙500 mg冲击3d后改为40mg/d,并联合环磷酰胺1.0g冲击1次(7月25日)及静脉丙种球蛋白20 g×5d(8月2日至8月6日)等治疗,期间抗GBM抗体逐渐下降(8月11日抗GBM抗体2.4RU/ml),但肾功能进行性损害(8月14日肌酐为376.0 μmol/L),血红蛋白下降至80.0g/L(8月11日);8月2日尿蛋白2+,红细胞计数5.8664×10~9个/L。患者及家属商议后要求转南京军区总医院,后电话随访得知患者肌酐下降(具体不详),目前失访。
术前嗜中性粒细胞/淋巴细胞比率可预测动静脉内瘘狭窄

自体血管内瘘(AVF)成熟不良和丧失功能的主要原因是狭窄和血栓形成,而狭窄又是形成血栓的主要原因。引发内瘘狭窄的原因很多,包括动-静脉或人造血管-静脉吻合口血流动力学的改变、内瘘手术的外科损伤、聚四氟乙烯(PTFE)人造血管(可吸引巨噬细胞释放细胞因子)、血透穿刺针损伤、尿毒症毒素刺激、氧化应激反应等,炎性反应在其中起重要作用。嗜中性粒细胞/淋巴细胞比率(neutrophil/lymphocyte ratio, NLR)和白细胞、C反应蛋白类似,都是反映炎性反应状态的指标,血常规检查即可获得。除了动静脉内径,患者术前的状况、炎性反应与术后AVF狭窄之间是否有相关性,是一个值得研究的问题。本研究探讨AVF狭窄与术前各项基础指标和炎性反应指标间是否存在关联。
临床护士共情疲劳影响因素的质性研究

目的了解临床护士共情疲劳风险因素,为探索有效的预控策略提供参考。方法以对象特征、工作环境和个人因素的3因子模型为指导,采用半结构式访谈法,对47名不同专科、已离职的和正在临床一线工作的注册护士进行深度访谈,运用主题分析法进行内容分析。结果提取的主题包括:对象特征6个,患者病程长且持续恶化或非预期的突然死亡,长时间遭受生理痛苦,家庭经济条件差,存在情感联系,非支持性的家庭动力学,负性情感或行为;工作环境3个,高强度的工作负荷,缺乏团队协作和有意义的认可,代际因素;个人因素3个,个人创伤性经历和过度的同理投入,临床经验缺乏,社会支持。结论需正确识别护士共情疲劳的影响因素,以便采取针对性的预控策略,促进护士身心健康,增加共情满意,减少职业倦怠。
医护共享平台在儿科护理风险评估中的应用

目的探讨医护共享平台在儿科护理风险评估中的应用效果。方法将入住呼吸消化病房及外科病房的患儿400例按病区床号分组,将病区1~25床分为对照组200例,26~50床为观察组200例,对照组由护士对所负责的患儿进行护理评估并填写评估结果,根据护理评估结果进行相应的护理;观察组实施基于医护共享平台的护理评估。结果观察组压疮、跌倒/坠床风险护理评估准确率显著高于对照组,而非难免性压疮、跌倒/坠床发生率显著低于对照组(P<0.05,P<0.01)。观察组患儿家长护理风险防范依从性显著高于对照组(P<0.01)。结论应用医护共享平台,有利于促进医护沟通合作,提高风险评估的准确性,保障患儿护理安全。
二甲医院护士组织支持感与职业获益感的相关性研究

目的了解二甲医院护士组织支持感与职业获益感的现状,分析两者的相关性。方法采用一般资料调查表,护士组织支持感量表和职业获益感量表对湖南省17所二甲医院的444名临床护士进行问卷调查。结果二甲医院护士组织支持感得分为3.06±0.47,职业获益感得分为4.06±0.58,组织支持感及其各维度得分与职业获益感及其各维度得分呈正相关(均P<0.01)。结论二甲医院护士组织支持感处于中等水平,职业获益感处于较高水平,组织支持感越高的护士职业获益感越强,应通过增强组织支持感来提升临床护士的职业获益感。
强制性运动疗法结合心理疗法对脑卒中偏瘫并抑郁患者上肢功能的影响

脑卒中是中老年人的常见病和多发病,其高致残率严重影响着患者的生活质量。脑卒中后抑郁(post stroke depression,PSD)是发生在脑卒中后的一种包括多种神经症状和躯体症状的复杂的情感障碍性疾病,其已被认为是影响脑卒中后功能康复的独立影响因素,其影响患者的神经功能恢复和日常生活活动能力,造成脑卒中后病程迁延,若不及时治疗将对随后的神经功能康复产生严重的不良影响。强制性运动疗法(constraint-induced movement therapy,CIMT)是以中枢神经系统可塑性理论为基础,通过限制使用健侧上肢,强制使用和训练偏瘫侧肢体,治疗脑卒中患者上肢运动功能障碍的一种康复治疗技术。本研究在CIMT的基础上,对患者增加心理疗法旨在对脑卒中抑郁患者出现的心理问题及障碍进行及时疏通,调节患者的心理承受能力,增强患者康复的信心。在治疗前后对治疗组与对照组进行了对比研究,分析了强制性运动疗法结合心理疗法对脑卒中抑郁患者上肢功能康复的作用。
Private Keyword-Search for Database Systems Against Insider Attacks

The notion of searchable encrypted keywords introduced an elegant approach to retrieve encrypted data without the need of decryption. Since the introduction of this notion, there are two main searchable encrypted keywords techniques, symmetric searchable encryption (SSE) and public key encryption with keyword search (PEKS). Due to the complicated key management problem in SSE, a number of concrete PEKS constructions have been proposed to overcome it. However, the security of these PEKS schemes was only weakly defined in presence of outsider attacks; therefore they suffer from keyword guessing attacks from the database server as an insider. How to resist insider attacks remains a challenging problem. We propose the first searchable encrypted keywords against insider attacks (SEK-IA) framework to address this problem. The security model of SEK-IA under public key environment is rebuilt. We give a concrete SEK-IA construction featured with a constant-size trapdoor and the proposed scheme is formally proved to be secure against insider attacks. The performance evaluations show that the communication cost between the receiver and the server in our SEK-IA scheme remains constant, independent of the sender identity set size, and the receiver needs the minimized computational cost to generate a trapdoor to search the data from multiple senders.
Static Scene Illumination Estimation from Videos with Applications

We present a system that automatically recovers scene geometry and illumination from a video, providing a basis for various applications. Previous image based illumination estimation methods require either user interaction or external information in the form of a database. We adopt structure-from-motion and multi-view stereo for initial scene reconstruction, and then estimate an environment map represented by spherical harmonics (as these perform better than other bases). We also demonstrate several video editing applications that exploit the recovered geometry and illumination, including object insertion (e.g., for augmented reality), shadow detection, and video relighting.
无发热的神经型布鲁菌病一例

讨论布鲁菌病是一种由布鲁杆菌引起的急性或慢性人畜共患的传染病,主要表现为发热、多汗、关节疼痛、乏力、木无力、听力下降,缺乏发热、大汗、头痛等典型的布鲁菌症状,初期诊断为“结核性脑膜炎”。后来脑脊液培养示布鲁菌,追问病史发现患者有接触牛粪病史,并经过针对性检查,最后确诊为“神经型布鲁菌病”。因此,在临床工作中遇到临床症状为神经系统损害的患者,即使没有发热、大汗、关节疼痛等布鲁菌病的典型表现,仍需要考虑布鲁菌病的可能,详细询问病史,流行病接触史是诊断的重要线索,完善病原学及血清学检查,从而早期做出正确诊断,避免误诊、漏诊。
不能遗忘的一次铀矿地质考察

在撰写《我国铀矿地质发展历程及主要经验》一书查阅相关资料时,未发现1989年以核工业地质局局长王陞学为团长的代表团到苏联进行访问情况的文字记载。这次访问是上世纪80年代中苏关系恢复后,中国铀矿地质界对苏联的首次访问,对中国铀矿地质发展的影响很大,是不能遗忘的一次铀矿地质考察。正是这次考察开始了中国与苏联新一轮的铀矿地质技术交流,中国铀矿勘查部署从南方调整到北方,特别是加强了对中新生代盆地可地浸砂岩型铀矿找矿工作,中国铀矿分布格局发生了根本性的改变。基于本人参加了这次访问,有责任向大家介绍有关情况。
伴有大量肾小球样结构的乳头状肾细胞癌一例

鉴别诊断:(1)后肾腺瘤:瘤组织由紧密排列的小腺管或小腺泡组成,瘤细胞大小较一致,核圆深染,核仁不明显;约50%的肿瘤有乳头状结构,可见管内有钝的乳头突起,似肾小球样结构;免疫组织化学示肿瘤细胞WT1、S-100蛋白和CD57均阳性,而EMA、CK7及P504s均阴性,与PRCC有明显不同。另外,近年来有文献报道Cadherinl7(CDH17)及BRAF(V600E)免疫组织化学阳性有助于后肾腺瘤的诊断。Yakirevich等首次对CDH17在后肾腺瘤、上皮样为主型肾母细胞瘤及实性型乳头状肾细胞癌中进行研究,通过免疫组织化学进行分析:正常成人肾实质不表达CDH17,在胎儿肾脏发育后期其肾小球和远端肾单位链接部开始出现CDH17的表达。大多数后肾腺瘤(81%)CDH17呈膜阳性表达,而上皮样主型肾母细胞瘤和实性型乳头状肾细胞癌均不表达。目前研究已证实约90%的后肾腺瘤存在BRAF(V600E)突变,并且发现BRAF基因第15号外显子突变在肾细胞癌中极其罕见。Utlager等通过研究发现BRAF(V600E)免疫组织化学在后肾腺瘤中表达敏感性达88%,特异性髙达100%。同时作者通过组织芯片技术评估了BRAF(V600E)免疫组织化学在不同肾细胞癌亚型中均无显著的表达。(2)黏液样小管状和梭形细胞癌(MTSCC):PRCC偶尔也可见梭形细胞成分,可与MTSCC混淆。但后者瘤组织常可见到大量小管状结构及特征性的黏液样基质,瘤细胞形态较温和,核分裂象稀少;免疫组织化学MTSCC与PRCC结果有较多重叠,均表达CK7、EMA、P504s和波形蛋白。Shen等推测MTSCC可能为PRCC的一个形态学变异,但MTSCC缺乏PRCC中常见的细胞遗传学异常,两类肿瘤患者预后不同,提示MTSCC和PRCC是肾脏肿瘤中2种完全独立的亚型。(3)肾类癌:原发性肾类癌非常罕见,一般为边界清楚的实性肿瘤。瘤细胞比较一致,胞质略嗜酸性,核仁不明显,核染色质呈细颗粒状,瘤细胞呈小梁状、条索状、缎带状、假腺样结构排列,局灶形成典型的菊形团样结构,免疫表型:嗜铬粒素A、突触素和CD56等神经内分泌标记均为阳性,有助于与PKCC鉴别。(4)肾母细胞瘤(上皮样型):好发于儿童,瘤组织内除上皮成分外,广泛取材常可见到多少不一的未分化肾胚芽组织以及向平滑肌、横纹肌、神经等成分分化的间质,且上皮细胞核细长、排列紧密、异型明显,核分裂象易见。免疫表型:瘤细胞表达WT1、波形蛋白,也可有灶状神经元特异性烯醇化酶、CK、结蛋白等表达,但P504s阴性。