mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
赋能教育在癌痛患者中的应用

目的探讨赋能教育对癌痛患者疼痛控制的影响。方法将80例癌痛患者随机分为干预组与对照组各40例,对照组给予常规癌痛知识教育,干预组在此基础上结合赋能教育进行干预。观察两组癌痛患者在出院后4周服药依从性、癌性爆发痛发生率、癌痛控制障碍得分及疼痛应对策略得分情况。结果出院后4周干预组服药依从性及疼痛应对策略评分显著高于对照组,爆发痛发生率及癌痛控制障碍得分显著低于对照组(P < 0.05,P < 0.01) 。结论对癌痛患者实施赋能教育能提高患者的服药依从性,减少癌性爆发痛发生率,减轻患者癌痛控制障碍,有利于患者采取积极的应对策略,从而更好地控制癌痛。
精神分裂症患者运动疗法的研究进展

从运动疗法的概念及其应用必要性、研究现状及影响因素进行分析,以期为精神分裂症患者的运动康复提供理论依据。提出为取得患者配合,确保运动安全,护士需做好健康教育、运动准备,监督运动过程,以及做好心理支持。并提出应依据患者自身状况,制定个性化运动方案,提高患者运动兴趣,积极关注患者锻炼过程中动机的动态变化对运动行为的影响。
带掌长肌腱的桡动脉掌浅支复合组织瓣修复指背软组织缺损

目的探讨应用带掌长肌腱的桡动脉掌浅支复合组织瓣移植修复指背软组织缺损的手术方法和疗效。方法自2014年9月至2017年11月,应用带掌长肌腱的桡动脉掌浅支复合组织瓣移植修复指背软组织缺损15例,男9例,女6例;年龄20~61岁,平均40.6岁。致伤原因:切割机割伤5例,电刨伤10例。受伤指别:拇指3例,示指6例,中指4例,环指2例。其中近、中节指背缺损9例,中、末节指背缺损6例;软组织缺损面积:2.8 cm×1.8 cm~4.2 cm×2.0 cm。伸肌腱缺损长度为2.1~4.0 cm,其中3例伴有伸肌腱止点损伤,5例伴有中节指骨骨折,3例伴有近节指骨骨折,2例伴有指骨背侧骨皮质缺损。皮瓣切取面积为3.0cm×2.1 cm-4.6 cm×2.2 cm,术后门诊随访观察皮瓣的质地、色泽、感觉恢复情况,以及指体外形、屈伸功能。结果本组15例皮瓣全部成活,其中1例术后第2天出现皮瓣暗紫,予间断拆线后皮瓣顺利成活。供区伤口均直接缝合。供、受区伤口一期愈合。随访4~12个月,平均6.5个月。皮瓣质地和外形良好,两点辨别觉达8~12 mm。供区除留有线形瘢痕外,无其他影响。指体屈、伸功能满意,根据中华医学会手外科学会上肢部分功能评定试用标准:优5例,良7例,可3例。结论带掌长肌腱的桡动脉掌浅支复合组织瓣移植修复指背软组织缺损,具有切取方便、供区和受区组织结构相近、可一期修复手背复合组织缺损的优点,疗效满意。
带掌长肌腱的静脉皮瓣在指背皮肤伴伸肌腱缺损中的应用

目的探讨应用带掌长肌腱的静脉皮瓣修复指背皮肤伴伸肌腱缺损的临床效果。方法自2011年10月至2016年9月,对27例34指指背皮肤伴伸肌腱缺损应用同侧前臂带掌长肌腱的静脉皮瓣修复。皮瓣面积1.5 cm×1.8 cm~2.5 cm×3.0 cm,供区直接缝合。术后门诊定期随访。结果本组27例34块皮瓣全部成活,其中11指皮瓣出现不同程度的水肿,皮瓣皮色发紫,表面水疱形成。经抬高患肢、应用甘露醇消肿,术后3~5 d好转,皮瓣肿胀减退,积液吸收,皮瓣完全成活。术后随访3~12个月,皮瓣色泽、质地与邻近组织相似,无明显萎缩,外形良好。按照肌腱修复后TAM/TPM标准评价,优19指、良9指、可4指、差2指,优良率达82.3%,临床效果满意。结论带掌长肌腱的静脉皮瓣一期修复手指背侧皮肤及伸肌腱缺损,缩短疗程,减轻患者的痛苦与经济负担,是修复指背皮肤伴肌腱缺损较好的方法。
中医膏方历史源流及现代发展状况

膏方是具有滋补养生、调治疗疾两大作用的中药内服制剂,以中医辨证论治、未病思想和整体观为指导,确立方药组成,体现了中医“治未病”的理念。本文通过对中医膏方的源流及历史沿革进行梳理,将其发展分为5个阶段,可反映它在历代中医的防病治病和养生保健方面的重要作用,有助于现代临床的预防保健医疗实践。
不同产地佛手GC指纹图谱及4种成分测定

目的建立不同产地佛手Citrus medica L. var. sarcodactylic Suingle的GC指纹图谱,并测定4种成分的含有量。方法佛手乙酸乙酯溶液的分析采用DB-5毛细管柱(30 m × 0.32 mm,0.25 μm);进样口温度250 ℃;检测器温度280 ℃;载气氮气体积流量3 mL/min;进样方式分流进样;分流比25 ∶ 1;进样量0.5 μL;程序升温条件以50 ℃为起始温度,保持1 min,后以2 ℃ /min升至100 ℃,保持1 min,再以10 ℃ /min升至250 ℃并保持5 min。理论板数按柠檬烯峰计算不低于100 000。应用SPSS 19.0软件对其进行聚类分析及主成分分析。结果27批样品指纹图谱中有11个共有峰,相似度均大于0.9。α-蒎烯、β-蒎烯、柠檬烯、γ-松油烯分别在0.404 16 ~ 1.010 4 μg (r = 0.999 5) 、 0.278 304 ~ 0.695 76 (r = 0.999 5) 、10.708 368 ~ 26.770 92 (r = 0.999 6) 、2.845 44 ~ 7.113 6 (r = 0.999 6)范围内线性关系良好,平均加样回收率(RSD)分别为96.12% (1.42%) 、98.53% (1.92%) 、97.43% (1.21%) 、 97.24% (1.19%) 。主成分分析提取了2个主成分,累计贡献率达86.769%。结论该方法准确稳定,重复性好,可用于佛手的质量控制。
锡类散联合美沙拉嗪治疗溃疡性结肠炎的Meta分析

目的对锡类散联合美沙拉嗪治疗溃疡性结肠炎进行Meta分析。方法检索PubMed、Embase、中国期刊全文数据库(CNKI) 、中国科技期刊全文数据库(VIP) 、中国生物医学文献数据库(CBM) 、万方数据库,收集关于锡类散联合美沙拉嗪治疗溃疡性结肠炎的随机对照试验。由2名研究者按照纳入、排除标准独立筛选文献,提取资料,评价文献方法学质量,并通过RevMan5.3软件进行Meta分析。结果共纳入12个随机对照试验,840例患者。与对照组(单用美沙拉嗪)比较,试验组(锡类散联合美沙拉嗪)能明显提高临床有效率[RR = 1.20,95% CI (1.13, 1.26),P < 0.000 01],改善临床症状[腹痛(SMD = - 3.34,95%CI (- 5.53, - 1.15),P < 0.01) 、血便(SMD = - 2.59,95%CI (- 4.56, - 0.62),P < 0.05) ],提高结肠镜检查疗效[RR = 1.20,95% CI (1.07,1.35),P < 0.01],但在降低不良反应发生率[RR = 1.03,95% CI (0.61,1.72),P > 0.05]、改善腹泻[SMD = - 2.79,95% CI (- 6.29,0.71),P > 0.05]方面效果不显著。结论锡类散联合美沙拉嗪治疗溃疡性结肠炎时,比单用美沙拉嗪具有更理想的疗效。
气管镜下介入操作中医务人员的职业损伤调查

气管镜检查和介入治疗在临床中广泛应用,该操作是否会引起慢性职业损伤,目前尚无相关报道,本研究的目的是了解医务人员在长期气管镜操作中的慢性损伤情况.
痛风相关知识问答(三)——降尿酸药物治疗

降尿酸治疗总的原则是:根据中华医学会风湿病学分会制定的“2016中国痛风诊疗指南”及2017年“中国高尿酸血症相关疾病诊疗多学科专家共识”中的相应推荐和阐述,参考2016年欧洲抗风湿病联盟(EULAR)和2012年美国风湿病学会(ACR)痛风管理指南,规范使用降尿酸药物的应用,将痛风患者血尿酸水平逐渐降至达标水平,且维持足够长的时间.
李斯特菌溯源分析方法及应用进展

单核细胞增生李斯特菌(Listeria monocytogenes,以下简称李斯特菌)为革兰阳性、兼性胞内寄生菌,广泛存在于自然界中,主要通过食物传播给人导致李斯特菌病.当食入李斯特菌污染的食品后可导致腹泻、腹痛等消化道症状;发生侵袭性感染时细菌可穿过肠道上皮细胞入血,导致菌血症、脑膜炎等;妊娠妇女感染可导致流产、早产及新生儿感染等严重并发症.老人、孕妇及免疫力低下者为李斯特菌感染高危人群.在美国由李斯特菌病导致的病死率占食源性疾病的19%,平均每年用于李斯特菌病的医疗花费及该病所致经济损失达28亿美元.
可疑恶性浆膜腔积液细胞块中免疫组织化学抗体的应用

浆膜腔积液细胞块免疫组织化学检测是近十余年来兴起并逐步得到推广应用的一种辅助性诊断技术,但由于免疫组织化学抗体种类繁多,在诊断中如何选择适宜的一线抗体成为难题.我们选取5种常用的间皮抗体和5种上皮性抗体,对72例浆膜腔积液细胞蜡块进行回顾性研究,探讨抗体组合在浆膜腔积液细胞蜡块中的应用价值.
新近认识的几种儿童罕见肿瘤或疾病的病理诊断

近年来,文献中陆续报道了一些好发于儿童及青少年的罕见肿瘤或疾病,这些疾病大多具有独特的临床病理、分子生物学特点,其治疗方案及预后也各有不同,因此,认识并准确诊断这些疾病尤为重要,本文将介绍几种在日常病理诊断工作中所遇到的一些儿童罕见肿瘤或疾病,以便广大病理工作者特别是儿科病理医师进一步了解这些疾病的病理特点,为病理诊断和研究提供依据.
鱼鳞病型蕈样肉芽肿一例

讨论鱼鳞病型蕈样肉芽肿为早期蕈样肉芽肿的一个少见亚型;成人发病多见,临床表现及组织病理学表现多样,可累及躯干及四肢,多表现为经典型/嗜毛囊性蕈样肉芽肿皮损合并鱼鳞病样改变,也可表现为鱼鳞样改变合并其他少见蕈样肉芽肿表现,如色素减退或溃疡性皮损.组织病理除了具有蕈样肉芽肿的特征表现外,还可能存在寻常型鱼鳞病的特征性改变,如角化不全、局灶性致密性角化过度、颗粒层减少或消失;免疫组化示浸润的异形淋巴细胞以CD3+、CD4+为主,少数表现为以CD8+为主的淋巴细胞浸润.寻常型鱼鳞病患者多在3岁前发病,表现为手背及四肢伸侧淡褐色至深褐色菱形或多角形鳞屑,紧贴皮肤,边缘呈游离状,可累及躯干及四肢屈侧,病理表现为中度角化过度伴颗粒层变薄或缺如,真皮正常或血管周围有散在淋巴细胞浸润,汗腺与皮脂腺减少.而本例患者的发病年龄、皮损形态及组织病理学表现均不支持.本病预后较好,但有少数进展至肿瘤期或转变为大细胞型淋巴瘤的病例报道.
Small Interfering RNA Targeting α-Fodrin Suppressing the Immune Response of Sjogren's Syndrome Mice

To the Editor: Sjogren's syndrome (SS) is a multisystem chronic autoimmune disease, and mainly affects the lacrimal and salivary glands, leading to ocular and oral dryness. SS is characterized by a large quantity of autoantibodies and involves multiple systems including the lymphatic system, blood, lungs, kidneys, liver, muscles, and joints. Late complications include interstitial pulmonary fibrosis, peripheral neuropathy, tracheobronchial sicca, blindness, arthralgia, oral candidiasis, and lymphoma. The main histopathological feature of SS is lymphocytic infiltration of the exocrine glands, resulting in acinar cell death, probably through apoptosis. The exact etiology and pathogenesis of SS are still not clear.
人体微生态学研究进展

微生态学是指微生物生态学或微生境的生态学.人体微生态学特指研究人体微生物的生态学,可按人体部位分类,肠道微生态学较早且更多地受到关注.人体微生态学的研究对象为微生物群(microbiota)或微生物组(microbiome),范畴包括微生物群(组)的特征及其与宿主的相互作用关系(图1).本文旨在阐明微生物群(组)的概念,微生物群(组)与宿主的相互作用和调控方式,并对现有研究技术进行综述,指出人体微生态学研究领域亟需解决的问题和发展方向.
EXISTENCE OF MULTIPLE SOLUTIONS FOR A FRACTIONAL p-LAPLACIAN SYSTEM WITH CONCAVE-CONVEX TERM

In this article, we study the existence of multiple solutions for the following system driven by a nonlocal integro-differential operator with zero Dirichlet boundary conditions where Ω is a smooth bounded domain in R~n, n > ps with s є2(0, 1) fixed, a(x), b(x), c(x) ≥ 0 and a(x), b(x), c(x) є L~∞(Ω), 1 < q < p and α,β > 1 satisfy p < α+β < p*, p* = np/n–ps. By Nehari manifold and fibering maps with proper conditions, we obtain the multiplicity of solutions to problem(0.1).
Enhanced photocatalytic degradation of lindane using metal-semiconductor Zn@ZnO and ZnO/Ag nanostructures

To achieve enhanced photocatalytic activity for the degradation of lindane,we prepared metal-semiconductor composite nanoparticles (NPs).Zn@ZnO core-shell (CS) nanocomposites,calcined ZnO,and Ag-doped ZnO (ZnO/Ag) nanostructures were prepared using pulsed laser ablation in liquid,calcination,and photodepositionmethods,respectively,without using surfactants or catalysts.The as-prepared catalysts were characterized by using X-ray diffraction (XRD),field-emission scanning electron microscopy,high-resolution transmission electron microscopy,ultraviolet-visible (UV-vis) spectroscopy,and photoluminescence spectroscopy.In addition,elemental analysis was performed by energy dispersive X-ray spectroscopy.The obtained XRD and morphology results indicated good dispersion of Zn and Ag NPs on the surface of the ZnO nanostructures.Investigation of the photocatalytic degradation of lindane under UV-vis irradiation showed that Zn@ZnO CS nanocomposites exhibit higher photocatalytic activity than the other prepared samples.The maximum degradation rate of lindane was 99.5% in 40 min using Zn@ZnO CS nanocomposites.The radical trapping experiments verified that the hydroxyl radical (·OH) was the main reactive species for the degradation of lindane.
Uranium speciation in coal bottom ash investigated via X-ray absorption fine structure and X-ray photoelectron spectra

Similar to chromium contamination,the environmental contamination caused by uranium in radioactive coal bottom ash (CBA) is primarily dependent on the chemical speciation of uranium.However,the relationship between uranium speciation and environmental contamination has not been adequately studied.To determine the relationship between uranium speciation and environmental contamination,X-ray absorption fine structure (XAFS) and X-ray photoelectron spectra (XPS) analyses were performed to determine the uranium speciation in CBA exposed to different chemical environments and simulated natural environments.The leachability of the different forms of uranium in the CBA was studied via a simulated acid rain leaching experiment,and the results showed that 57.0% of the total uranium was leached out as U(VI).The results of a linear combination fit (LCF) of the X-ray absorption near edge structure (XANES) spectrumrevealed that in the rawCBA,the uranium mainly occurred as U3O8 (71.8%).However,in the iron-rich particles,the uranium mainly occurred as UO2 (91.9%) after magnetic separation.Magnetite is a ubiquitous ferrousbearing oxide,and it was effective for the sorption of U(IV).The result of FeSO_4 leaching experiment indicated that 96.57% of total uranium was reduced from U(VI) to U(IV) when infiltrated with the FeSO_4 solution for 6 months.This result clearly demonstrated the changes in chemical valence of uranium in the coal ash and provided a conceptual principle for preventing uranium migration from ash to the surrounding soil and plants.
Catalytic decomposition performance for O_3 and NO_2 in humid indoor air on a MnO_x/Al_2O_3 catalyst modified by a cost-effective chemical grafting method

Processes based on non-thermal plasma (NTP) for indoor air treatment inevitably lead to the formation of toxic by-products such as ozone (O_3) and nitrogen oxides (NO_x).Adding a step of heterogeneous catalysis in series with NTP could allow for the decomposition of the by-products.Therefore,different catalysts were developed based on transition metal oxides,such as NiOx,CoOx and MnO_x with different weight percentage 1,5 and 10 wt.%,deposited on a γ-Al_2O_3 support.The O_3 removal efficiency (ORE) and the NO_x removal efficiency (NRE) were very encouraging in dry air:about 65% and 80%,respectively,by using 2 g 5 wt.% MnO_x/Al_2O_3 catalyst under the experimental conditions.However,strongly negative effects of relative humidity (RH) on the catalytic decomposition performance were observed.To overcome this limitation,the catalyst surface was modified to make it hydrophobic using a cost-effective chemical grafting method.This treatment consisted in impregnating the 5 wt.% MnO_x/Al_2O_3 catalyst with different trichloro(alkyl)silanes (TCAS).The effects of different linker lengths and amounts of TCAS for the hydrophobicity and the decomposition performance of surface-modified catalysts under humid conditions were investigated.Our results show that the surface-modified catalyst with the shortest linker and 0.25 mmol/gcat of modifying agent represents the best catalytic decomposition performance for O_3.Its ORE is 41% at 60% RH,which is twice that of the non-modified catalyst.
Analyzing the activities of visitors of the Leiden Ranking website

Purpose: To get a better understanding of the way in which university rankings are used. Design/methodology/approach: Detailed analysis of the activities of visitors of the website of the CWTS Leiden Ranking. Findings: Visitors of the Leiden Ranking website originate disproportionally from specific countries. They are more interested in impact indicators than in collaboration indicators, while they are about equally interested in size-dependent indicators and size-independent indicators. Many visitors do not seem to realize that they should decide themselves which criterion they consider most appropriate for ranking universities. Research limitations: The analysis is restricted to the website of a single university ranking. Moreover, the analysis does not provide any detailed insights into the motivations of visitors of university ranking websites. Practical implications: The Leiden Ranking website may need to be improved in order to make more clear to visitors that they should decide themselves which criterion they want to use for ranking universities. Originality/value: This is the first analysis of the activities of visitors of a university ranking website.
TDP-43 regulates cancer-associated microRNAs

Aberrant regulation of miRNA genes contributes to pathogenesis of a wide range of human diseases, including cancer. The TAR DNA binding protein 43(TDP- 43), a RNA/DNA binding protein associated with neurodegeneration, is involved in miRNA biogenesis. Here, we systematically examined miRNAs regulated by TDP- 43 using RNA-Seq coupled with an siRNA-mediated knockdown approach. TDP-43 knockdown affected the expression of a number of miRNAs. In addition, TDP-43 down-regulation led to alterations in the patterns of different isoforms of miRNAs(isomiRs) and miRNA arm selection, suggesting a previously unknown role of TDP- 43 in miRNA processing. A number of TDP-43 associated miRNAs, and their candidate target genes, are associated with human cancers. Our data reveal highly complex roles of TDP-43 in regulating different miRNAs and their target genes. Our results suggest that TDP-43 may promote migration of lung cancer cells by regulating miR-423-3p. In contrast, TDP-43 increases miR-500a- 3p expression and binds to the mature miR-500a-3p sequence. Reduced expression of miR-500a-3p is associated with poor survival of lung cancer patients, suggesting that TDP-43 may have a suppressive role in cancer by regulating miR-500a-3p. Cancer-associated genes LIF and PAPPA are possible targets of miR-500a- 3p. Our work suggests that TDP-43-regulated miRNAs may play multifaceted roles in the pathogenesis of cancer.
新型降糖药物及其应用

既往医学证据显示,降糖药物的应用无疑对糖尿病患者的血糖和各种并发症的改善与控制起到至关重要的作用。临床医师需要重视糖尿病患者药物治疗,并根据不同降糖药物的作用特点、基本作用机制、疗效、副作用、价格等多方面因素综合考量,做到及时用药、合理用药。
胎盘植入的围手术期管理

近年来,随着世界范围内包括我国剖宫产术后再次妊娠及高龄孕妇的比例上升,胎盘植入的发生率不断增高.胎盘植入的主要风险为致命性产后出血及高子宫切除率,严重者甚至导致孕产妇死亡.
Convergence analysis of distributed Kalman filtering for relative sensing networks

We study the distributed Kalman filtering problem in relative sensing networks with rigorous analysis.The relative sensing network is modeled by an undirected graph while nodes in this network are running homogeneous dynamical models.The sufficient and necessary condition for the observability of the whole system is given with detailed proof.By local information and measurement communication,we design a novel distributed suboptimal estimator based on the Kalman filtering technique for comparison with a centralized optimal estimator.We present sufficient conditions for its convergence with respect to the topology of the network and the numerical solutions of n linear matrix inequality (LMI) equations combining system parameters.Finally,we perform several numerical simulations to verify the effectiveness of the given algorithms.
巨大子宫颈及阔韧带肌瘤变性一例MRI表现

综上所述,利用MRI可多方位成像和多参数成像的优势,观察病灶与子宫的关系,综合分析肿块在各序列上的信号特点,能显著提高本病的诊断准确率。本病主要与卵巢肿瘤和肠道间质瘤鉴别诊断:(1)卵巢的良性肿瘤多为囊性,边界清楚,体积较小,易鉴别;卵巢恶性肿瘤多为囊实性,实性成分在T2WI上呈稍高信号,增强扫描呈不均匀强化,且多伴有转移和腹水。(2)肠道间质瘤以侵及和推移肠管为主,很少引起子宫形态改变或与子宫关系密切;在T2WI上多呈高信号, DWI上实性成分呈高信号,与子宫肌瘤的信号特点不同。
五指山小型猪近交系异种移植产业化研发进展

为了早日实现五指山小型猪(WZSP)近交系异种移植产业化目标,努力推进近交繁育获得近交系,同时开展克服异种移植免疫排斥和猪内源性逆转录病毒(PERV)传染生物安全性两大难题的研发内容。本文从WZSP近交系双基因敲除克隆猪繁育成功、猪-猴异种角膜内皮移植取得突破性进展、WZSP近交系PERV无传染性群体建立、WZSP近交系是理想的动物模型和异种移植供体等方面,介绍WZSP近交系异种移植产业化的研发进展。
Solvent-Triggered Self-Folding of Hydrogel Sheets

Intense investigations have been attracted to the development of materials which can reconfigure into 3D structures in response to external stimuli.Herein we report on the design and self-folding behaviors of hydrogels composed of poly (ethylene glycol) methyl ether methacry-late (OEGMA) and 2-(2-methoxyethoxy) ethyl methacrylate (MEO2MA).Upon immersion into a variety of solvents at room temperature,the resulting P(MEO2MA-co-OEGMA) hydrogel sheets self-fold into 3D morphologies,and the observed transformation in shape is reversible.We further show that composition of the gel,gaseous environment,and preparation procedure play important roles in the self-folding behavior of the resulting hydrogels.This work provides a facile approach for fabricating self-folding hydrogels.
To Construct High Level Secure Communication System: CTMI Is Not Enough

Public key cryptographic (PKC) algorithms, such as the RSA, elliptic curve digital signature algorithm (ECDSA) etc., are widely used in the secure communication systems, such as OpenSSL, and a variety of information security systems. If designer do not securely implement them, the secret key will be easily extracted by side-channel attacks (SCAs) or combinational SCA thus mitigating the security of the entire communication system. Previous countermeasures of PKC implementations focused on the core part of the algorithms and ignored the modular inversion which is widely used in various PKC schemes. Many researchers believe that instead of straightforward implementation, constant time modular inversion (CTMI) is enough to resist the attack of simple power analysis combined with lattice analysis. However, we find that the CTMI security can be reduced to a hidden t-bit multiplier problem. Based on this feature, we firstly obtain Hamming weight of intermediate data through side-channel leakage. Then, we propose a heuristic algorithm to solve the problem by revealing the secret (partial and full) base of CTMI. Comparing previous necessary input message for masking filtering, our procedure need not any information about the secret base of the inversion. To our knowledge, this is the first time for evaluating the practical security of CTMI and experimental results show the fact that CTMI is not enough for high-level secure communication systems.
Coexistence Analysis between 5G System and Fixed- Satellite Service in 3400-3600 MHz

The 3400-3600 MHz band is one of the most important candidate frequency bands for the rollout of 5G system. However, the coexistence between 5G system and fixed-satellite service (FSS) in this frequency band is one of the most challenging problems for both academic researchers and industry engineers. In this paper, the saturation interference from 5G base stations to the existing FSS above 3600 MHz is analyzed and the coexistence solution is achieved, which can reduce the interference and guarantee the coexistence between 5G system and FSS. Furthermore, the Monte Carlo simulation, laboratory test and field test are carried out to verify the coexistence solution. Results show that an isolation distance of 1-2 km is required to avoid the saturation interference in terms of the adjacent bands scenario. To further reduce the isolation distance to 50 m, additional isolation of 35 dB will be necessary, which can be fulfilled by installing a filter at the input port of LNB from a real implementation perspective.
Tribological Performance of Bioimplants: A Comprehensive Review

Total joint replacements (TJR) have been a huge success for orthopaedic surgery in the past century and are gaining increasing importance today due to the aging population. However, the short longevity of artificial joints is one of the major problems in bioimplant industry and needs to be rectified since an increasing number of young people, with more active lifestyles, must receive TJR. Wear mechanisms are discussed in this paper to describe the root causes of the failures and to give some general ideas to increase the lifespan of artificial joints. The suitable material combination is of great importance for the wear resistance ofbioimplants, and bioceramics will exert a crucial effect in their future progress. Other materials, such as metal alloys and polymers, are also discussed in this paper. Surface finish is another factor affecting the tribological performance of bioimplants. In recent years, surface texture technology has fascinated many researchers, and a good design of texture pattern requires a comprehensive understanding of wear mechanisms, material properties, and dynamic fluid theory. This review also covers a summary of in vitro wear tests, including simulators, lubricant, and testing parameters.
Pin1在神经退行性疾病中的作用机制及研究进展

肽基脯氨酰顺/反异构酶NIMA互作蛋白1(peptidyl-prolyl cis/trans isomerases,NIMA-interacting1,Pin1)可以识别底物磷酸化的丝氨酸/苏氨酸-脯氨酸(phosphor-Ser-Pro or phosphor-Thr- Pro,pSer/Thr-Pro)基序,通过催化磷酸化底物的顺反异构,对底物蛋白的结构和功能产生影响,在增殖、分化、存活等多种细胞生物学过程中发挥重要作用。近年来研究发现Pin1的表达和功能异常与多种神经退行性疾病相关。由于Pin1催化底物丰富,同时参与不同疾病发病的关键因子不尽相同,因此Pin1在不同神经退行性疾病中发挥的作用也不一样。本文从多种常见的神经退行性疾病的角度展开讨论,就Pin1在不同的神经退行性疾病中所发挥的作用和机制展开综述。
The Resonance Suppression for Parallel Photovoltaic Grid-connected Inverters in Weak Grid

Obvious resonance peak will be generated when parallel photovoltaic grid-connected inverters are connected to the weak grid with high grid impedance, which seriously affects the stability of grid-connected operation of the photovoltaic system. To overcome the problems mentioned above, the mathematical model of the parallel photovoltaic inverters is established. Several factors including the impact of the reference current of the grid-connected inverter, the grid voltage interference and the current disturbance between the photovoltaic inverters in parallel with the grid-connected inverters are analyzed. The grid impedance and the LCL filter of the photovoltaic inverter system are found to be the key elements which lead to existence of resonance peak. This paper presents the branch voltage and current double feedback suppression method under the premise of not changing the topological structure of the photovoltaic inverter, which effectively handles the resonance peak, weakens the harmonic content of the grid current of the photovoltaic grid-connected inverter and the voltage at the point of common coupling, and improves the stability of the parallel operation of the photovoltaic grid-connected inverters in weak grid. At last, the simulation model is established to verify the reliability of this suppression method.
家禽疫苗免疫有效阻断H7N9病毒的流行和对人的感染

H7N9流感自2013年在中国出现后,已引起5波次的人的疫情,共造成1 567人感染,615人死亡(2013年3月~2018年9月),病死率为39.2 %.其中,发生在2016年10月至2017年9月的第5波疫情中共有766人感染,引起全球高度关注,产生对今后会有更多人感染的担忧.造成2013年人感染的低致病力H7N9病毒(LPAIV)来源于家禽,该病毒经过近4年的进化,在2017年初突变为高致病性禽流感病毒(HPAIV);HPAIV可在哺乳动物内复制过程中获得适应性突变,而具有在哺乳动物间经呼吸道飞沫传播的能力,对人类蕴藏更大威胁.
在诠释中创新———评《本草纲目影校对照》

早在1958年,毛泽东主席就曾经在卫生部党组《西医学中医离职学习班的总报告》的批示中说: “中医药学是一个伟大的宝库,应当努力发掘,加以提高。”这句话包涵了两件事———继承与创新。而诠释学,正是沟通二者的桥梁。中医药学重视发掘传承,必须对重要的古医籍进行系统化、规范化、多方位、高层次的诠释研究,积学以启真,述学以为道,使中医古籍为今人所理解、所应用。诠释的任务在于传达、翻译、解释、阐明与创新,就是要在客体(即被诠释的文本)框架上,充分重视训诂学等研究,并在此基础上,为客体赋予时代的精神,增添时代的价值。所以,在诠释学研究中,尤其要保持自由之思想,独立之精神!唯有不断创新,才能保持一门学科长期发展的活力。
Robustness analysis of interdependent PV grids and communication network based on complex network

Currently,the photovoltaic ( PV) cloud network is an important research point in energy Internet. From the perspective of the robustness analysis of PV cloud network,traditional robustness index,the relative size of the giant connected component before and after the cascading,which is focused on the giant component,is not appropriate for the distributed PV network because of the big difference between PV generators and large power grid. In this paper,a new index is proposed,the minimum removed nodes number ( MRNN) ,which can make the entire system collapse,to evaluate the robustness of PV cloud network system. Simulation results show that MRNN can clearly indicate the system robustness under different parameters.
Lutetium(177Lu) oxodotreotide(Lutathera)

Lutetium(177Lu) oxodotreotide由法国Advanced Accelerator Applications(3A)公司研发,于2017年9月26日经欧盟委员会批准在欧洲上市,又于2018年1月26日经美国FDA批准在美国上市,其商品名为Lutathera,用于治疗生长抑素受体阳性的胃肠胰腺神经内分泌肿瘤.