mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
The use of metal hydrides in fuel cell applications

This paper reviews state-of-the-art developments in hydrogen energy systems which integrate fuel cells with metal hydride-based hydrogen storage. The 187 reference papers included in this review provide an overview of all major publications in the field, as well as recent work by several of the authors of the review. The review contains four parts. The first part gives an overview of the existing types of fuel cells and outlines the potential of using metal hydride stores as a source of hydrogen fuel. The second part of the review considers the suitability and optimisation of different metal hydrides based on their energy efficient thermal integration with fuel cells. The performances of metal hydrides are considered from the viewpoint of the reversible heat driven interaction of the metal hydrides with gaseous H2. Efficiencies of hydrogen and heat exchange in hydrogen stores to control H2 charge/discharge flow rates are the focus of the third section of the review and are considered together with metal hydride – fuel cell system integration issues and the corresponding engineering solutions. Finally, the last section of the review describes specific hydrogen-fuelled systems presented in the available reference data.
肾上腺梗死性结节一例

床上主要表现为腹痛,但常常与腹部其他疾病引起的腹痛相混淆,无明显特征性。影像学检查可以发现病变,但定性极为困难,肾上腺供血动脉及引流静脉均较为细小,常规CT平扫或增强扫描难以显示栓塞血管,相关激素(皮质醇、醛固酮)检查均无升高,往往诊断为无功能性腺瘤。回顾性分析该病例手术所见,仔细分析其CT表现,病灶中心无强化区域亦为软组织密度(CT值约49 HU),而不同于腺瘤的坏死液化;病灶周边强化,代表血供较丰富,且与右侧肾上腺强化较相似,再结合临床病史除外其他急腹症,符合肾上腺梗死性结节诊断。但最终诊断仍需病理学检查。
罕见纵隔滑膜肉瘤一例

纵隔滑膜肉瘤影像学表现缺乏特征性,其确诊需依靠病理、免疫组织化学和SS18-SSX融合基因检测。此患者临床上采用手术切除治疗,术后辅助化疗,目前患者情况良好。
颌面部占位病变--请分析病变性质

鉴别诊断:(1)腮腺淋巴瘤: MRI平扫肿瘤呈长T_1、等或长T_2信号,边缘清晰有包膜,增强扫描呈轻度强化。(2)血管外皮瘤:MRI表现为T_1WI呈等信号或稍高混杂信号,T_2WI呈混杂信号,增强后肿瘤明显强化。(3)原始神经外胚层肿瘤:MRI呈等T_1、稍长T_2信号,其内可见囊变坏死及出血,增强后实性部分可明显强化。
Immunotherapy against cancer-related viruses

Approximately 12% of all cancers worldwide are associated with viral infections. To date, eight viruses have been shown to contribute to the development of human cancers, including Epstein-Barr virus (EBV), Hepatitis B and C viruses, and Human papilloma virus, among others. These DNA and RNA viruses produce oncogenic effects through distinct mechanisms. First, viruses may induce sustained disorders of host cell growth and survival through the genes they express, or may induce DNA damage response in host cells, which in turn increases host genome instability. Second,they may induce chronic inflammation and secondary tissue damage favoring the development of oncogenic processes in host cells. Viruses like HIV can create a more permissive environment for cancer development through immune inhibition, but we will focus on the previous two mechanisms in this review. Unlike traditional cancer therapies that cannot distinguish infected cells from non-infected cells, immunotherapies are uniquely equipped to target virus-associated malignancies. The targeting and functioning mechanisms associated with the immune response can be exploited to prevent viral infections by vaccination,and can also be used to treat infection before cancer establishment. Successes in using the immune system to eradicate established malignancy by selective recognition of virus-as-sociated tumor cells are currently being reported. For example, numerous clinical trials of adoptive transfer of ex vivo generated virus-specific T cells have shown benefit even for established tumors in patients with EBV-associated malignancies. Additional studies in other virus-associated tumors have also been initiated and in this review we describe the current status of immunotherapy for virus-associated malignancies and discuss future prospects.
Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding

The global outbreak of SARS in 2002-2003 was caused by the infection of a new human coronavirus SARS-CoV. The infection of SARS-CoV is mediated mainly through the viral surface glycoproteins, which consist of S1 and S2 subunits and form trimer spikes on the envelope of the virions. Here we report the ectodomain structures of the SARS-CoV surface spike trimer in different conformational states determined by single-particle cryo-electron microscopy. The conformation 1 determined at 4.3 A resolution is three-fold symmetric and has all the three receptor-binding C-terminal domain 1 (CTDls) of the S1 subunits in “down" positions. The binding of the “down"CTDls to the SARS-CoV receptor ACE2 is not possible due to steric clashes, suggesting that the conformation 1 represents a receptor-binding inactive state. Conformations 2-4 determined at 7.3, 5.7 and 6.8 A resolutions are all asymmetric, in which one RBD rotates away from the "down" position by different angles to an “up" position. The “up" CTD1 exposes the receptor-binding site for ACE2 engagement, suggesting that the conformations 2-4 represent a recep-tor-binding active state. This conformational change is also required for the binding of SARS-CoV neutralizing antibodies targeting the CTD1. This phenomenon could be extended to other betacoronaviruses utilizing CTD1 of the S1 subunit for receptor binding, which provides new insights into the intermediate states of coronavirus pre-fusion spike trimer during infection.
On the Variation of Divergent Flow: An Eddy-flux Form Equation Based on the Quasi-geostrophic Balance and Its Application

Based on basic equations in isobaric coordinates and the quasi-geostrophic balance, an eddy-flux form budget equation of the divergent wind has been derived. This newly derived budget equation has evident physical significance. It can show the intensity of a weather system, the variation of its flow pattern, and the feedback effects from smaller-scale systems (eddy flows). The usefulness of this new budget equation is examined by calculating budgets for the strong divergent-wind centers associated with the South Asian high, and the strong divergence centers over the Tibetan Plateau, during summer (June– August) 2010. The results indicate that the South Asian high significantly interacts with eddy flows. Compared with effects from the mean flow (background circulation), the eddy flows’ feedback influences are of greater importance in determining the flow pattern of the South Asian high. Although the positive divergence centers over the Tibetan Plateau intensify through different mechanisms, certain similarities are also obvious. First, the effects from mean flow are dominant in the rapid intensification process of the positive divergence center. Second, an intense offsetting mechanism exists between the effects associated with the eddy flows’ horizontal component and the effects related to the eddy flows’ convection activities, which weakens the total effects of the eddy flows significantly. Finally, compared with the effects associated with the convection activities of the mean flow, the accumulated effects of the eddy flows’ convection activities may be more favorable for the enhancement of the positive-divergence centers.
Global Land Surface Climate Analysis Based on the Calculation of a Modified Bowen Ratio

A modified Bowen ratio (BRm), the sign of which is determined by the direction of the surface sensible heat flux, was used to represent the major divisions in climate across the globe, and the usefulness of this approach was evaluated. Five reanalysis datasets and the results of an offline land surface model were investigated. We divided the global continents into five major BRm zones using the climatological means of the sensible and latent heat fluxes during the period 1980–2010: extremely cold, extremely wet, semi-wet, semi-arid and extremely arid. These zones had BRm ranges of (-1, 0), (0, 0.5), (0.5, 2), (2, 10) and (10, +1), respectively. The climatological mean distribution of the Bowen ratio zones corresponded well with the Koppen-like climate classification, and it reflected well the seasonal variation for each subdivision of climate classification. The features of climate change over the mean climatological BRm zones were also investigated. In addition to giving a map-like classification of climate, the BRm also reflects temporal variations in different climatic zones based on land surface processes. An investigation of the coverage of the BRm zones showed that the extremely wet and extremely arid regions expanded, whereas a reduction in area was seen for the semi-wet and semi-arid regions in boreal spring during the period 1980–2010. This indicates that the arid regions may have become drier and the wet regions wetter over this period of time.
Putting Faces to Names: Snapshots of Two Committee Meetings, 95 Years Apart, Emphasize Continuous International Cooperation in the Atmospheric Sciences

Spectacular advances have been made in the atmospheric sciences on a global level during a period of one hundred years or more, which is arguably most evident through “the quiet revolution of numerical weather prediction” (Bauer et al., 2015). A cornerstone of such scientific success is generally regarded to be steady and orchestrated international cooperation. The intergovernmental World Meteorological Organization (WMO) has since 1952 been serving as the global umbrella organization for the National Hydro-Meteorological Services, with its work divided into a number of technical commissions. However, nongovernmental activities date back much further, e.g., to the first International Meteorological Congress in 1873, in Vienna, Austria, and the International Meteorological Conference in 1891, in Munich, Germany. The latter brought together some 35 directors of meteorological services in their personal capacities, rather than as governmental delegates. It was then decided to structure the work through technical sub-committees (Davies, 1990, p. 4), one of which was tasked with, and named, the Measurement of the Motion and Altitude of Clouds. Years later, it was renamed as the International Commission for the Scientific Investigation of the Upper Air, and can be regarded as a forerunner of today’s Commission for Atmospheric Sciences (CAS) of the WMO. Nowadays, the WMO possesses a rich sub-structure, which partly reaches beyond its bounds in the form of the World Climate Research Programme (WCRP), with the International Council for Science (ICSU) and the International Oceanographic Commission (IOC) within UNESO as co-sponsors. The WCRP is composed of four core projects, one of which has been dealing with Stratospheretroposphere Processes and their Role in Climate (SPARC) since 1992, as documented in a unique series of as yet 48 newsletters,regularly appearing twice a year (available online at http://www.sparc-climate.org/publications/newsletter/ ).
BOUND STATES OF SCHRODINGER EQUATIONS WITH ELECTROMAGNETIC FIELDS AND VANISHING POTENTIALS

We study the bound states to nonlinear Schrodinger equations with electromagnetic fields ${\text{i}}h\frac{{\partial \psi }}{{\partial t}} = {\left( {\frac{h}{i}\nabla  - A\left( x \right)} \right)^2}\psi  + V\left( x \right)\psi  - K\left( x \right)|\psi {|^{p - 1}}\psi  = 0$, on ${\mathbb{R}_ + } \times {\mathbb{R}^N}$. Let $G\left( x \right) = {\left[ {V\left( x \right)} \right]^{\frac{{p + 1}}{{p - 1}} - \frac{N}{2}}}{\left[ {K\left( x \right)} \right]^{ - \frac{2}{{p - 1}}}}$ and suppose that $G\left( x \right)$ has $k$ local minimum points. For $h > 0$ small, we find multi-bump bound states ${\psi _h}\left( {x,t} \right) = {e^{ - iEt/h}}{u_h}\left( x \right)$ with ${u_h}$ concentrating at the local minimum points of $G\left( x \right)$ simultaneously as $h \to 0$. The potentials $V\left( x \right)$ and $K\left( x \right)$ are allowed to be either compactly supported or unbounded at infinity.
Novel yellow colored flame compositions with superior spectral performance

The production of colored flames is the primary purpose of military signaling, projectile tracing, and illuminating devices. Certain elements and compounds when heated to high temperature have the unique property of emitting lines or narrow bands in the visible region (380-780 nm). This study, reports on the development of novel yellow colored flame compositions with enhanced spectral performance in terms of luminous intensity, and color quality to standard Russian yellow tracer. The light intensity and the imprint spectra of developed yellow flares were measured using digital luxmeter and UV-Vis. spectrometer respectively. The main giving of this study is that the light intensity, and color quality of Russian yellow tracer were improved by 287%, and 170% respectively. This was accomplished by means of optimizing the ratio of novel binder to color source using aluminum metal fuel. Aluminumbased formulations were found to maximize the formation of yellow reactive emitting specimens, and to eliminate any interfering incandescent emission resulted from MgO. Quantification of yellow color emitting specimens in the combustion gaseous products was achieved using chemical equilibrium thermodynamic code named ICT (Institute of Chemical Technology in Germany, Virgin 2008); in an attempt to judge the light quality. This improvement in yellow flare performance established the rule that the emission intensity increases as the reaction temperature increases. In the meantime upper limit of temperature was avoided to maximize the color quality.
Parental attitudes towards influenza vaccination for children in South India

Background: The rate of influenza vaccination is low for children in India. The purpose of this study is to assess parental attitudes towards influenza vaccination in South India. Methods: Participants were parents who brought their children to the Well Baby Clinic of Christian Medical College Hospital, Vellore, India for routine immunization. Participants answered questions by written survey while waiting for their children's vaccination. Results: A total of 456 surveys were completed (403 parents did not opt for trivalent influenza vaccination and 53 opted for influenza vaccination). The majority (53.60%) of those parents who did not accept influenza vaccination identified the lack of a doctor's recommendation as the main reason. When asked separately, many non-acceptors (44.91%) indicated that they did not believe or were not sure that the influenza vaccine was effective. Nearly all non-acceptors (92.56%) stated that they would opt for influenza vaccination if a doctor recommended it. Conclusions: The most common reason that parents not opting for influenza vaccination for their children was the lack of recommendation by a doctor. The results of this study suggest that recommendation by a doctor is a more important factor than belief in efficacy, cost, or convenience in parental decision-making regarding childhood influenza vaccination in India, unlike the United States where parents are less likely to follow recommendations.
Generation of Targeted Point Mutations in Rice by a Modified CRISPR/Cas9 System

CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated Cas9 endonuclease)-mediated genome editing has revolutionized biological research and crop improvement because of its specificity, simplicity, and versatility (reviewed in Komor et al., 2016a). Editing a gene by CRISPR/Cas9 only has three requirements: (1) expression of the nuclear localized Cas9 protein; (2) production of a guide RNA (gRNA) molecule, whose first 20 nucleotides are complementary to the target gene; (3) the NGG PAM site that is located immediately adjacent to the 3' end of the target sequence (Figure 1A). In the presence of a gRNA, Cas9 generates a double-strand break (DSB) at the target sequence. DSB repair by the error-prone, non-homologous end-joining (NHEJ) mechanism often leads to small deletions or insertions at the target site, providing a valuable venue to generate knockout and loss-of-function mutants. The majority of the reported CRISPR/Cas9-mediated gene editing in plants belongs to this category (Miao et al., 2013; Xie and Yang, 2013; Ma et al., 2015; Wang et al” 2015; Char et al” 2016; Gao et al., 2016). While such mutants are very valuable in defining gene functions, their applications in crop improvement are somewhat limited because many agriculturally important traits are conferred by single-nucleotide polymorphisms or by dominant gain-of-function point mutations. Homology-directed repair (HDR) of the DSB at specific locations can provide a feasible approach to achieve gene replacement. However, it has been very challenging to make use of HDR in plants to introduce point mutations because of the very low frequency of targeted integration. So far only a few special cases of CRISPR/Cas9-mediated HDR have been reported in plants (Sun et al., 2016). NHEJ-mediated repair may also be used to introduce point mutations through gene replacement if the target sequences of CRISPR/Cas9 are located in introns (Li et al., 2016). Nevertheless, it is still a major challenge to generate targeted point mutations in plants.
Arabidopsis thaliana RECEPTOR DEAD KINASE1 Functions as a Positive Regulator in Plant Responses to ABA

Abscisic acid (ABA) is a major phytohormone involved in important stress-related and developmental plant processes. Membrane-delimited ABA signal transduction plays an important role in early ABA signaling, but the molecular mechanisms connecting core signaling components to the plasma membrane remain unclear. Plants have evolved a large number of receptor-like kinases (RLKs) to modulate diverse biological processes by perceiving extracellular stimuli and activating downstream signaling responses. In this study, a putative leucine-rich repeat-RLK gene named RECEPTOR DEAD KINASE1 (AtRDK1) was identified and characterized in Arabidopsis thaliana. RDK1 promoter-GUS analysis revealed that RDK1 is expressed ubiquitously in the various tissues in Arabidopsis, and its expression is mainly induced by ABA. In the presence of ABA, RDK1-deficient rdk1-1 and rdk1-2 lines showed significant resistance in cotyledon greening and root growth, whereas RDK1-overexpressing lines showed enhanced sensitivity. Consistently, the expression of ABA-responsive genes was significantly downregulated in rdk1 mutant seedlings, which were also hypersensitive to drought stress with increased water loss. Interestingly, RDK1 was found to be an atypical kinase localized to the plasma membrane and did not require its kinase activity during ABA-mediated inhibition of seedling development. Accordingly, RDK1 interacted in the plasma membrane with type 2C protein phosphatase ABSCISIC ACID INSENSITIVE1 (ABI1); this interaction was further enhanced by exogenous application of ABA, suggesting that RDK1-mediated recruitment of ABI1 onto the plasma membrane is important for ABA signaling. Taken together, these results reveal an important role for RDK1 in plant responses to abiotic stress conditions in an ABA-dependent manner.
Experimental determination of the azimuthal and radial mode orders of a partially coherent LG_(pl) beam

It is known that one can determine the mode orders (i.e., the azimuthal order and radial order) of a partially coherent LG_(pl) beam (i.e., a partially coherent vortex beam) based on the measurement of the cross-correlation function (CCF) and the double correlation function (DCF) together. The technique for measuring the CCF is known. In this Letter, we propose a method for measuring the DCF. Based on the proposed method, the determination of the mode orders of a partially coherent LG_(pl) beam is demonstrated experimentally.
良性前列腺增生中西医结合诊疗指南(试行版)

良性前列腺增生(benign prostatic hyperplasia, BPH)是指中老年男性(50岁以上)组织学上前列腺间质、腺体成分的增生和解剖学上前列腺的增大(benign prostatic enlargement, BPE),以尿动力学上的膀胱出口梗阻(bladder outlet obstruction, BOO)和临床上主要表现的下尿路症状(lower urinary tract symptoms, LUTS)为特征的一种疾病。BPH属中医"精癃"范畴。
IgG4相关性腹膜后纤维化的研究进展

IgG4相关性腹膜后纤维化(RPF)是一种临床少见病,以腹膜后腔纤维硬化组织形成伴IgG4嚷细胞浸润为主要特点,是RPF的一种亚型。RPF是指以包绕血管生长的腹膜后腔纤维硬化组织增生为特征的一组疾病,多累及肾脏以远的腹主动脉和髂动脉,增生组织可压迫周围的输尿管和下腔静脉,引起相应临床表现。可将RPF分为特发性腹膜后纤维化(iRPF)和继发性RPF。目前发现,既往诊断的IRPF病例中有一部分应归属于另一类具有更为广泛疾病谱的疾病——IgG4相关性疾病(IgG4-RD)。
48例垂体柄增粗MRI表现

垂体柄是连接神经垂体与下丘脑的重要结构。此处病变的主要临床表现包括尿崩、视力障碍、头痛及内分泌症状等。垂体柄增粗(pituitary stalk thickening,PST)病因复杂多样。随着MRI技术的广泛应用,PST作为独立的影像学诊断,其检出率不断升高,但病因学诊断仍是临床工作中的一大难题。本研究通过回顾性分析48例垂体柄增粗病例,探讨其MRI影像学及临床表现特征。
狼疮性脑病合并胶质母细胞瘤一例

25%~75%的NPSLE患者可有MRI表现异常,通常表现为缺血、水肿、脑白质病变和脑萎缩性改变。胶质母细胞瘤,恶性程度高,病程短,向周围浸润生长迅速,血供不足,因此往往伴随中心的大片状坏死和肿瘤周围的大片状水肿,典型MRI表现为混杂长T_1、长T_2信号,增强呈花环样强化,与狼疮脑病的急性脑梗死表现类似,发生于狼疮性脑病患者,易被相当然地诊断为狼疮性脑病。本例行~1H-MRS扫描,避免了误诊。~1H-MRS可对活体化学成分进行定量分析,反映细胞的代谢信息, Cho是一种细胞膜代谢产物,反映细胞的增殖状况。胶质母细胞瘤实质成分细胞增殖活跃,而急性梗死期脑细胞只是处于水肿状态,增殖活性不会升高,故可以根据Cho峰是否升高加以鉴别。提示在诊断狼疮性脑病时遇到疑似占位性病变时,应行~1H-MRS扫描以排除肿瘤,从而提高诊断的准确性,采取更合理的治疗方法。
肾脏上皮样血管平滑肌脂肪瘤一例

笔者查阅了国内有关肾EAML影像学的文献。纪建松等报道了15例肾脏EAML的CT平扫和增强表现,认为CT平扫病灶呈稍低或等高密度,可累及肾髓质部分或向外生长,增强扫描动脉期明显或较明显均匀强化,部分病灶内有增粗迂曲的血管,呈"快进快出"方式。胡晓云等报道10例肾脏EAML的CT平扫呈相对高密度,增强呈现"快进慢出"的表现。俞琳芽等报道了18例肾EAML的CT表现为肿瘤大部分与肾实质界限清楚,突出于肾轮廓外,表现为"劈裂征"和"皮质掀起征"等良性肿瘤征象,强化方式有"快进快出"及"快进慢出"两种。王佳丽等认为肾EAML出现不同的强化方式与病灶内组织成分不同有关,若瘤体内存在畸形厚壁血管,在动脉期会出现明显强化,若瘤体内微血管网和上皮样细胞丰富,则会持续强化。本例肾脏EAML的CT表现与文献报道基本一致,肿瘤位于肾盂内,平扫呈稍高密度,边缘光整,增强扫描皮质期明显强化,髓质期和排泄期强化迅速减退,表现"快进快出"的改变,而临床上却无血尿表现。影像学上肾脏EAML主要与肾癌和肾AML相鉴别:(1)肾癌。分叶多见,边界不清,周围结构更易被侵犯,可出现假包膜,强化方式为"快进快出",但在分泌期有明显低于肌肉组织密度的坏死、囊变灶。(2)肾脏AML。EAML多为乏脂肪的肿块,而典型的AML含有成熟脂肪成分,可为鉴别要点,但当典型AML缺少脂肪成分以平滑肌为主时则鉴别困难。
免疫组化切片褪色再染HE方法探讨

随着人们生活水平的日益提高以及医疗条件的不断改善,病理切片向高等级医院会诊也越来越多,患者不及时归还HE切片及组织蜡块的情况也时有发生,病理档案资料仅存有一些免疫组化切片,如果想把此病例作为教学和学术交流将难以进行。我们通过反复试验,摸索出一种将免疫组化标记褪色后,重新进行HE染色的病理技术,现介绍如下。
中国林业科学研究院国家自然科学基金资助情况分析与管理工作探讨

国家自然科学基金是我国支持基础研究的主要渠道之一,对繁荣我国基础研究、加强科研人才队伍建设以及提高自主创新能力等方面都做出了重要贡献。本文分析了中国林业科学研究院1986—2015年度国家自然科学基金项目的资助情况,总结了管理模式和方法,并对科研院所“十三五”国家自然科学基金的管理工作进行了探讨。
Synthesis of Visible-Light-Driven g-C_3N_4/PPy/Ag Ternary Photocatalyst with Improved Photocatalytic Performance

g-C_3N_4/PPy/Ag ternary photocatalyst was synthesized by a three-step method. Firstly, graphitic carbon nitride(g-C_3N_4)photocatalyst was obtained by sintering melamine at high temperature, then a series of g-C_3N_4/PPy composite photocatalysts were prepared by in-situ polymerization of pyrrole, and finally the g-C_3N_4/PPy/Ag ternary composite photocatalyst was obtained by depositing Ag on the surface of g-C_3N_4/PPy. The photocatalytic activities of as-prepared samples were evaluated by degradation of antibiotic tetracycline(TC)under visible light. The influence of the amounts of polypyrrole(PPy)and Ag on the photocatalytic activity of g-C_3N_4/PPy/Ag ternary photocatalyst was investigated. Both PPy and Ag played critical roles for the enhanced photocatalytic activity of g-C_3N_4/PPy/Ag. The g-C_3N_4/PPy/Ag composites exhibited remarkably improved photocatalytic activities for degrading TC compared with g-C_3N_4, g-C_3N_4/PPy and g-C_3N_4/Ag. Besides, the photocatalytic mechanism was also analyzed. The band match of PPy with g-C_3N_4 benefited the separation of photo-generated carriers in g-C_3N_4, and the deposited Ag nanoparticles played important roles as an electron mediator due to the surface plasmon resonance(SPR)effects. The present study offered new insight into the design of the economical and gently environment-friendly synthesis of highly efficient photocatalysts.
Robust Ti-and Zr-Based Metal-Organic Frameworks for Photocatalysis

Photocatalysis represents a promising pathway for the direct conversion of solar energy to valuable chemical energy. Metal-organic frameworks(MOFs), which are constructed from metal/metal clusters interconnected with organic ligands, have recently emerged as a promising candidate in this field. Among various MOFs, Ti-and Zr-based MOFs have gained intensive interest in photocatalysis due to their relation to the commonly used photo-catalyst(TiO_2)and high stability. In this review, we summarized the recent applications of Ti-and Zr-based MOFs in solar fuel production, including water reduction and oxidation, CO_2 reduction and organics syntheses. Strategies to improve the MOF-based photocatalysis via improving their light absorption and facilitate the charge separation were also demonstrated. Finally, opportunities and challenges facing the MOFs-based photocatalysis, especially the Ti-and Zr containing MOFs were addressed.