mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
The Genomic Characterization of Enterovirus D68 from 2011 to 2015 in Beijing, China

A retrospective surveillance study on enterovirus D68 was performed in Beijing, China, following the largest and most widespread EV-D68 infection, which occurred in the USA. From January 2011 to July 2015, EV-D68 was identified in 12 individuals with respiratory infections in Beijing, China. The phylogenetic relationships based on the genomic sequence alignment showed that there were two lineages circulating in Beijing from 2011 to 2015. Eight EV-D68 strains belonged to group 1 and four belonged to group 3. All EV-D68 strains from Beijing in 2014 were separately clustered into subgroup II of group 1. Based on these results, we concluded that the Beijing EV-D68 strains had little association with the EV-D68 strains circulating in the 2014 USA outbreak.
苹果锈果类病毒陕西秦冠分离物的鉴定与序列分析

陕西省是我国苹果种植大省,苹果锈果病的发生严重影响其苹果产业,该病是由苹果锈果类病毒(Apple scar skin viroid,ASSVd)引起的,陈炜和田波(1985)首次在国内发现了ASSVd的RNA,Hashimoto & Koganezawa(1987)首次报道了ASSVd的全基因组序列。郭瑞等(2005)报道了我国ASSVd辽宁和新疆苹果分离物的序列,郝璐等(2015)发现ASSVd在陕西和辽宁苹果产区发病率较高。笔者在陕西乾县苹果园中发现果树表现出疑似ASSVd类病毒感染的症状,为了鉴定致病病原并了解ASSVd类病毒陕西分离物的特点,本试验通过小RNA测序手段,获得并分析了该类病毒陕西分离物的全基因组序列,以期为更有效防治该病害提供理论依据。
单细胞ICP-MS技术分析水中藻类的纳米颗粒摄入

观测和研究细胞对于元素离子和纳米颗粒的摄入,对于人类健康和环境安全都具有非常重要的意义.本文通过利用ICP-MS配备的单细胞检测技术,对待测藻类摄入元素离子和纳米颗粒的行为进行了观察和研究,探讨了不同培养液浓度、曝光时间对于单细胞中离子和纳米颗粒含量的影响,以及细胞分裂过程对于摄入行为的影响.
顶空自动进样器结合气相色谱仪测定土壤和沉积物中挥发性芳香烃

随着社会迅猛发展,固废、废水、废气都会导致土壤/沉积物污染.本文采用顶空-气相色谱法测定土壤和沉积物中的12种挥发性芳香烃,方法检出限可达0.79—4.48 μg·kg~(-1).该方法操作简单,检出限低,且适用性强,可用于土壤和沉积物中挥发性芳香烃的快速定性定量测定.
Experimental investigation of ash deposits on convection heating surfaces of a circulating fluidized bed municipal solid waste incinerator

Incineration of municipal solid waste (MSW) is a waste treatment method which can be sustainable in terms of waste volume reduction, as well as a source of renewable energy. During MSW combustion, increased formation of deposits on convection heating exchanger surfaces can pose severe operational problems, such as fouling, slagging and corrosion. These problems can cause lower heat transfer efficiency from the hot flue gas to the working fluid inside the tubes. A study was performed where experiments were carried out to examine the ash deposition characteristics in a full-scale MSW circulating fluidized bed (CFB) incinerator, using a newly designed deposit probe that was fitted with six thermocouples and four removable half rings. The influence of probe exposure time and probe surface temperature (500, 560, and 700°C) on ash deposit formation rate was investigated. The results indicate that the deposition mass and collection efficiency achieve a minimum at the probe surface temperature of 560°C. Ash particles are deposited on both the windward and leeward sides of the probe by impacting and thermophoretic/ condensation behavior. The major inorganic elements present in the ash deposits are Ca,Al and Si. Compared to ash deposits formed on the leeward side of the probe,windward-side ash deposits contain relatively higher Ca and S concentrations, but lower levels of Al and Si. Among all cases at different surface temperatures, the differences in elemental composition of the ash deposits from the leeward side are insignificant. However, as the surface temperature increases, the concentrations of Al, Si, K and Na in the windward-side ash deposits increase, but the Ca concentration is reduced. Finally,governing mechanisms are proposed on the basis of the experimental data, such as deposit morphology, elemental composition and thermodynamic calculations.
Hexabromocyclododecane and tetrabromobisphenol A in sediments and paddy soils from Liaohe River Basin, China: Levels, distribution and mass inventory

brominated flame retardants and widely present in the environment and biota. The levels,spatial distributions and mass inventories of HBCD and TBBPA were investigated in sediments and paddy soils from the Liaohe River Basin in northeast China. The concentrations of ΣHBCD and TBBPA were in the range of not detected (nd) to 4.02 ng/g dry weight (dw) and 0.03 to 4.06 ng/g dw, respectively. γ-HBCD was dominated in sediments,while the abundance of α-HBCD was relatively high in paddy soils. The spatial distributions of HBCD and TBBPA in surface sediments and paddy soils indicated that the local point-input was their major source. The significant correlation between total organic carbon (TOC) contents and the HBCD levels suggested that TOC content also exerted an influence on the distribution of HBCD in sediments. Meanwhile, it was found that the irrigation with river water was not the major transportation pathway of HBCD and TBBPA in paddy soils. Based on the study, it was estimated that there were about 1.67 tons HBCD and 2.20 tons TBBPA deposited into sediments of the Liaohe River system every year. The total mass inventories of HBCD and TBBPA in sediments were far higher than that in paddy soils.
协同创新驱动下的地理信息产业技术公共服务平台构建

为促进地理信息产业创新主体间资源共享与协同服务,汇聚创新资源,提升创新要素活力,促进产业发展,从创新要素构成、创新要素服务模式、公共服务平台研发等方面研究构建了地理信息产业技术公共服务平台,为测绘地理信息人才、技术、设备、数据等资源共享、企业创新发展与协同服务等提供了解决思路。
冰川和常年积雪常态化地理国情监测开展模式初探

应“十三五”开展常态化地理国情监测之需求,以冰川和常年积雪为监测对象,对冰雪常态化地理国情监测的开展模式进行了初步探索。主要内容有:冰雪监测内容、监测周期和监测方法,冰雪统计分析与评价。对于冰雪统计分析与评价,主要结合相关行业需求,重点在于指标构建。
自定位手持式三维激光扫描仪精度测试与分析

三维激光扫描技术是一种高精度高效率的测绘新技术,在逆向工程、三维可视化、虚拟现实等领域被广泛使用。手持式三维激光扫描仪是三维激光扫描仪的一种,其便携性和高精度的特点使其在文物考古、医学等领域具有独特的优势。但在应用过程中,实际获取的扫描数据精度往往会受到仪器自身、扫描目标及外界环境的影响。本文对手持式三维激光扫描仪的误差来源进行了分类,并针对各个误差来源进行分析,然后以EXAscan手持式三维激光扫描仪为例,设计了相应的试验方案并对其精度进行了测试与分析。
TEQC软件下的GPS数据质量控制

利用基于Matlab二次开发的SPEC模块在Windows下对TEQC质量检核生成的绘图文件进行直观显示,便于了解测站观测环境以剔除不良时间段和卫星的观测数据。对剔除前后的数据利用自编软件进行基线解算,试验表明,利用TEQC处理后的基线精度有了一定程度的提高。
室内地图的设计与表达

从空间认知的角度出发,分析了室内空间的特点,总结出其所带来的影响室内空间认知的因素,依此提出了室内地图设计的原则。在上述原则指导下进行了地图要素的分类和选取,提出了基于空间围合的边界表达方法和基于锚固点理论的要素突出表达方法,并对室内地图符号进行了设计。
机器学习辅助下的概率积分法参数预计模型寻优

收集整理了多组地表移动观测站资料作为训练样本和检验样本,以工作面地质采矿条件为输入集,概率积分法预计参数为输出集,利用机器学习方法对概率积分法预测参数进行了预测。选取支持向量机、BP神经网络和偏最小二乘法3种机器学习方法对训练样本进行训练,利用训练所得模型预测检验样本中的概率积分法预测参数,并将预测结果与观测站实测值进行对比。结果表明,利用支持向量机预测下沉系数、主要影响角正切值及水平移动系数的精度最高,其平均相对误差分别达到7.46%、4.00%、 13.17%;拐点偏距及开采影响传播角利用偏最小二乘法预计精度最高,平均相对误差分别为10.83%、0.88%;总体而言支持向量机的预测精度最为稳定。
Selective maintenance problem for series–parallel system under economic dependence

In view of the high complexity of the objective world, an economic dependence between subsystems(paired and unpaired)is proposed, and then the maintenance cost and time under different economic dependences are formulated in a simple and consistent manner. Selective maintenance problem under economic dependence(EDSMP)is presented based on a series–parallel system in this paper. A case study shows that the system reliability is promoted to a certain extent, which can validate the validity of the EDSMP model. The influence of the ratio of set-up cost on system performance is mainly discussed under different economic dependences. Several existing improvements of classical exhaust algorithm are further modified to solve a large sized EDSMP rapidly. Experimental results illustrate that these improvements can reduce CPU time significantly. Furthermore the contribution of each improvement is defined here, and then their contributions are compared thoroughly.
On Submanifolds Whose Tubular Hypersurfaces Have Constant Higher Order Mean Curvatures

Motivated by the theory of isoparametric hypersurfaces,we study submanifolds whose tubular hypersurfaces have some constant higher order mean curvatures. Here a k-th order mean curvature Q_k~v (k ≥ 1) of a submanifold M~n is defined as the k-th power sum of the principal curvatures, or equivalently, of the shape operator with respect to the unit normal vector v. We show that if all nearby tubular hypersurfaces of M have some constant higher order mean curvatures, then the submanifold M itself has some constant higher order mean curvatures Q_k~v independent of the choice of Many identities involving higher order mean curvatures and Jacobi operators on such submanifolds are also obtained. In particular, we generalize several classical results in isoparametric theory given by E. Cartan, K. Nomizu,H. F. Münzner,Q. M. Wang, et al. As an application,we finally get a geometrical filtration for the focal submanifolds of isoparametric functions on a complete Riemannian manifold.
不同剂量辛伐他汀治疗稳定性心绞痛效果比较

冠心病发病率随年龄增加〔1,2〕。他汀类药物除调节血脂作用外,还可减轻动脉粥样斑块炎症反应,保护内膜功能〔3,4〕,在冠心病临床治疗中广泛应用。辛伐他汀为选择性竞争性3-羟基-3-甲基戊二酸单酰辅酶A还原酶(HMG-CoA)抑制剂,是他汀类药物中降低胆固醇、低密度脂蛋白作用最强的药物。但在临床应用中,选择何种剂量治疗效果最佳,不良反应更少目前尚无统一意见。本研究旨在探讨不同剂量辛伐他汀治疗稳定性心绞痛的临床疗效及不良反应。
泉州地区非小细胞肺癌人群中表皮生长因子受体基因突变分析

目的探讨泉州地区非小细胞肺癌(NSCLC)患者表皮生长因子受体(EGFR)基因突变的情况。方法收集130例泉州地区NSCLC组织或胸腔积液,用ADx-ARMS技术检测NSCLC患者石蜡组织标本EGFR DNA突变19、20及21的突变,同时分析其突变与临床特征的关系。结果130例NSCLC中共检出37例EGFR基因突变,EGFR突变阳性率为28.46 %(37/130),女性EGFR基因突变率(26/54)48.15%,显著高于男性(12/78)15.4%(P<0.05);EGFR突变外显子19和21突变占总突变的100.0 %;腺癌突变发生率为89.19%(33/37)。结果泉州地区NSCLC患者EGFR基因突变以外显子19和21突变为主。结论临床上对未进行EGFR检测的晚期NSCLC腺癌女性患者,可考虑先予EGFR酪氨酸激酶抑制剂进行诊断性治疗。
老年综合评估干预对老年慢性心力衰竭住院患者预后的影响

目的探讨老年综合评估(CGA)干预对老年慢性心力衰竭(CHF)住院患者预后的影响。方法收集老年CHF患者290例,随机分为CGA干预组和对照组各145例,干预组入院时行CGA评估,并据评估结果制定综合治疗方案,组织多学科诊疗,对症治疗等措施,对照组予对症治疗。随访CGA干预对老年CHF患者死亡率、再入院率及急诊率等方面的影响。结果CGA干预组患者死亡率、再入院率及急诊就诊率均显著低于对照组(χ~2值分别为9.569,4.378,9.410,P均<0.05)。结论CGA干预可降低患者死亡率、再入院率及急诊就诊率。
血尿酸在老年2型糖尿病并发非酒精性脂肪性肝病患者肝纤维化进展中的预测价值

目的探讨血尿酸(UA)在老年2型糖尿病并发非酒精性脂肪性肝病患者肝纤维化进展中的预测价值。方法将385例老年2型糖尿病患者根据肝脏彩超结果分为肝纤维化组组195例和对照组190例。调查糖尿病病程,测量体重、身高;检测血小板计数(PLT)、白蛋白(ALB)、天冬氨酸转氨酶(AST)、丙氨酸转移酶(ACT)、血肌酐(Scr)、SUA;测定24 h尿量,计算UA清除率和UA排泄分数。肝纤维化组根据血UA分为高UA组42例和正常UA组153例,分别计算非酒精性脂肪性肝病纤维化评分。结果肝纤维化组高UA血症的患病率(21.5%)明显高于对照组(8.9%)(P<0.05);高UA组预测晚期肝纤维化进展率为35.7%,显著高于正常UA组(20.9%,P=0.047)。排除晚期肝纤维化率正常UA组与高UA组差异无统计学意义(15% vs 11.9%,P>0.05)。结论血UA在老年2型糖尿病并发非酒精性脂肪性肝病患者的肝纤维化进展中具有一定的预测价值,结合非酒精性脂肪性肝病纤维化评分,为高危人群的评估和防治提供依据。
川芎嗪对阿尔茨海默病大鼠学习记忆能力和细胞周期蛋白E、P21表达的影响

目的探讨川芎嗪(TMP)对阿尔茨海默病(AD)模型大鼠学习记忆和细胞周期蛋白(Cyclin)E、P21表达的影响及作用机制。方法大鼠海马区注入β淀粉样蛋白(Aβ)_(1~42)制作AD模型。Morris水迷宫实验检测大鼠学习记忆能力;免疫组化法检测海马区CyclinE和P21蛋白的表达。结果低、高剂量TMP组均能改善AD大鼠的学习记忆能力(P<0.01,P<0.05),下调大鼠海马CyclinE蛋白表达(P<0.05),上调P21蛋白表达(P<0.05)。低、高剂量TMP组相比无明显差异。结论TMP能改善AD大鼠学习记忆功能,下调CyclinE蛋白和上调P21蛋白表达,减轻神经细胞凋亡。
山东省养老护理需求现状

目的调查山东省养老护理需求现状。方法采用自行设计老年护理需求问卷进行分层抽样方式进行资料获取并分析。结果养老护理费用给个人及社会造成严重的负担,养老护理保障制度缺位,养老护理需求缺乏评判标准。结论建议政府相关部门整合现有资源,出台养老护理保障制度,建立老年护理需求评估机制,以适应老龄化社会高速增长的老年护理需求。
血清胸腺嘧啶核苷激酶1水平与肺癌患者临床病理特征及预后的关系

目的探讨肺癌患者血清胸腺嘧啶核苷激酶(TK)1与肺癌患者临床病理特征及预后的关系。方法肺癌患者80例为肺癌组,取66例健康者为对照组,采用化学发光法检测TK1表达,并收集患者临床病理特征与1、3年生存情况。结果肺癌患者中TK1阳性率为40.00%(32/80),显著高于健康对照组的13.64%(9/66)(P<0.05),肺癌患者TK1阳性率在性别、吸烟史、淋巴结转移及病理类型上未见统计学差异,而与远处转移及TMN分期有关(P<0.05);肺癌TK1阳性与阴性患者在1年生存率上未见统计学差异(P>0.05),但3年生存率阳性患者明显低于阴性患者(P<0.05)。结论血清TK1在肺癌患者中高表达,并与患者发生远处转移及TMN分期密切相关,且预后生存率低。因此,血清TK1可作为指导肺癌临床分期及判断预后的独立预测指标。
老年胃反流性食管炎患者的临床特征、食管动力学及酸暴露特点

目的探讨胃反流性食管炎(GERD)老年患者的临床特征、食管动力学及食管动态pH值的变化特点。方法280例GERD患者,根据年龄分为老年组(≥60岁)137例、非老年组(<60岁)143例,观察并比较两组患者的临床症状、食管动力及蠕动功能及24 h动态食管反流pH值水平。结果老年组患者胃灼热、反酸发生率显著低于非老年组患者(P<0.05);两组患者吞咽困难、食欲不佳、体重下降、呕吐、黑便、嗳气发生率差异均无统计学差异(P>0.05)。老年组患者的食管下括约肌(LES)静息压、LES残余压、LES松弛率显著低于非老年组患者(P<0.05);两组患者的LES长度、LES中心距鼻孔、UESP测定值差异均不无统计学意义(P>0.05)。老年组患者的卧位反流时间、立位酸清除时间及卧位酸清除时间所占百分比和DeMeester积分均显著高于非老年组患者(P<0.05);两组患者的立位反流时间差异无统计学意义(P>0.05)。结论GERD老年患者的典型临床症状表现较非老年患者减弱,食管动力性变差、酸暴露时间增加,这些因素均可进一步增加疾病的严重程度。
GM6001对糖皮质激素性股骨头坏死大鼠骨组织功能及骨代谢指标的影响

目的探讨静脉注射基质金属蛋白酶抑制剂GM6001对糖皮质激素性股骨头坏死(SINFH)大鼠骨组织功能及骨代谢指标的影响。结果采用健康SD大鼠臀肌注射甲基泼尼松龙制备SINFH模型,将72只模型大鼠随机分为SINFH组,低剂量GM6001(GM6001-L)组和高剂量GM6001(GM6001-H)组。GM6001-L组和GM6001-H组在造模同时经尾静脉注射50、100 mg/kg,1次/w,连续8 w。另取24只正常SD大鼠于臀肌注射相同剂量生理盐水作对照。分别于造模2、4、6、8 w检测各组血清磷、血清钙水平,检测造模8 w的血清骨代谢指标〔骨碱性磷酸酶(BALP)、骨钙素(BGP)、破骨细胞型抗酒石酸酸性磷酸酶(StrACP)和降钙素(CT)〕水平,采用双能X线骨密度测定仪检测造模8 w的股骨转子及股骨头的骨密度,通过股骨头形态学观察计数视野内成骨细胞数与破骨细胞数。结果与对照组相比,SINFH组的血清钙磷、BGP、CT、股骨转子和股骨头的骨密度及股骨头成骨细胞计数均降低,而BALP水平及StrACP活性均和破骨细胞均升高(P<0.05);GM6001可升高SINFH大鼠的血清钙磷、BGP、CT水平、股骨头成骨细胞计数及股骨转子和股骨头的骨密度,降低BALP水平及StrACP活性均和破骨细胞计数,与SINFH组和对照组均有统计学差异(P<0.05);GM6001-H组的以上指标均优于GM6001-L组(P<0.05)。结论GM6001可改善SINFH大鼠的血清钙磷和骨代谢指标水平并升高股骨骨密度,抑制MMP活性在糖皮质激素性所致股骨头坏死中有较好的防治价值。
白藜芦醇对高糖诱导肾小管上皮细胞凋亡的保护作用及机制

目的探讨白藜芦醇抑制高糖诱导人近端肾小管上皮细胞株(HK-2)的凋亡及可能机制。方法MTT检测HK-2细胞活力;Hoechst染色法、caspase-3活性检测细胞凋亡;DCFH-DA检测细胞内活性氧水平;Real-time PCR检测Nrf2 mRNA表达;Western印迹法检测Nrf2蛋白表达。结果30 mmol/L葡萄糖能显著降低HK-2细胞活力,诱导细胞凋亡,上调细胞内活性氧的水平,并下调Nrf2 mRNA和蛋白表达。10 μmol/L白藜芦醇预处理能部分逆转高糖的作用。结论白藜芦醇对高糖诱导的HK-2凋亡的保护机制可能与抑制活性氧的生成和上调Nrf-2的表达有关。
进展期胃癌术前分期研究现状

胃癌是人类最常见的恶性肿瘤之一,我国是胃癌的高发区。在精准医疗时代,以因期施治为核心的胃癌规范化综合治疗理念已成共识,如何提高术前胃癌分期的准确性,使术前分期不再是雾里看花,而使基于准确术前分期的精准治疗成为可能?本文结合目前最新的肿瘤分期系统和辅助检查手段来阐述进展期胃癌的术前分期现状及临床意义。
肝胰十二指肠切除术治疗胆囊癌的指征和技术要点

胆囊癌的发病率并不算高,但生物学行为非常恶劣,极易发生局部浸润和远处转移,加之进展缓慢、症状隐匿,大部分胆囊癌在确诊时已经发展到进展期,伴有肝脏浸润、淋巴结转移、远端胆管浸润、胰头部浸润等,目前以吉西他滨、顺铂、卡培他滨、5-氟尿嘧啶(5-FU)为主的化疗、放疗以及新出现的一些靶向治疗药物如厄洛替尼、贝伐单抗、程序性死亡受体1(PD-1)抗体等,对胆囊癌的治疗效果都不佳,尚未有行之有效的药物可提高晚期胆囊癌的存活率。因此,扩大的胆囊癌根治术仍是外科医生考虑选择的主要方案。在这些扩大的根治术中,肝胰十二指肠切除术(hepatopancreatoduodenectomy,HPD)极具挑战性,具有很高的围手术期病死率和术后并发症发生率,但却可以改善晚期胆囊癌的预后。本文拟对该术式的相关手术指征、技术要点及预后等进行探讨。
泰山紫草多糖超声提取工艺优化及其体外抗肿瘤活性

目的优化泰山紫草多糖的超声提取工艺,并对其体外抗肿瘤活性进行评价。方法星点设计-响应面法优化提取工艺,MTT法检测体外抗肿瘤活性。结果最佳条件为提取时间25 min,提取温度60 ℃,料液比1 ∶ 25,提取两次,提取率3.261%。多糖对人宫颈癌HeLa细胞、人肝癌HepG2细胞、人胃癌SGC-7901细胞的IC_(50)值分别为(9.17 ± 0.07) 、(3.89 ± 0.09) 、(6.79 ± 0.04) mg /mL。结论该方法简便,提取率高,泰山紫草多糖的体外抗肿瘤活性显著。
Gas Sources for Natural Gas Hydrates in the Permafrost Region of the Qilian Mountains

As a new type of gas hydrates, the natural gas hydrates in the perfost region of the Qilian Mountains are characterized by their shallow burial depth, well-developed coal seam, high content of heavy hydrocarbons and multiple sets of mature and over-mature source rocks. Gas sources of these gas hydrates in the study area include coal-type gas and oil-type gas. However, there is still controversy about which type dominates in these gas hydrates. The aim of this study is to establish criteria for discriminating gas sources of gas hydrates in the permafrost area, and then to find out the main source of the gas hydrates in the Qilian Mountains.
Discovery of Palaeozoic Karsts in the Qaidam Basin and Their Oil and Gas Prospects

Complex geological factors have been constraining the oil and gas exploration in the Paleozoic strata of the Qaidam Basin, although there are high-quality hydrocarbon source rocks. One of the most important reasons may be reservoir densification due to the multiple stages of destructive cementation, which has hindered our understanding of the Paleozoic petroleum enrichment rules in the Qaidam basin. In recent years, the petroleum exploration success of the Paleozoic karst reservoirs in the adjacent basins has also promoted us to focus on the karst petroleum reservoirs.
Geochronological and Geochemical Evidence for the Sedimentary Transformation from the Banxi Period to Nanhua Glacial Period

There has been considerable debate about the definition of the lower boundary of Nanhua System by far. One definition is based on sedimentary sequence of different stages of basin evolution, focusing on whether deposits of the Banxi Period should be classified as Nanhua System. Another is the onset time of Nanhua glacial period. Sedimentary sequences from the Banxi to Nanhua glacial period is comparatively complete in the Hunan-Guizhou-Guangxi neighboring regions, which should be the most favorable areas for selecting the lower boundary stratotype of Nanhua system. For further discussing the deposition record, the nature of boundary surface and timing of the sedimentary-tectonic transformation from the Banxi Period to Nanhua glacial period, we carried out a series of detailed research on sedimentary sequences and sections between the late Banxi and Nanhua glacial deposition in sedimentology, geochemistry and isotopic chronology. Thus, it can provide new sedimentological and isotopic geochronological evidence for selecting proper lower boundary section of Nanhua system.
How Central Asian Orogeny Evolves: New Insights from End-Permian to Middle Triassic Magmatic Record along the Solonker Suture Zone

The modern Earth is characterized by two types of orogens: collisional orogen and accretionary orogen. It is widely accepted that the Central Asian Orogenic Belt (CAOB) is made up of widespread multiple ancient archipelagos. It has been recognized as a non-collisional orogen, contrasting with the archetypical Alpine-Himalayan-type collisional orogens. Although the CAOB is traditionally compared to subduction-accretion systems that have been well studied, all accretionary orogens ultimately passed into a collisional phase at the end of the orogenic Wilson cycle due to ocean closure and termination of subduction, which will lead to subsequent crustal shortening, thickening and reworking. Therefore, the archipelago-type CAOB may also preserve a terminal collision record, although this is not a classic continental collision at all. Since typical regional collisional features are absent, its tectonic evolution from accretion to collision remains speculative. The type of collision is consistent with ophiolite-strewn complexes and broad suture zones, sometimes referred to as "cryptic" sutures along the Solonker-Xar Moron suture zone. More important, such magmatism has not previously been well documented.
Very Low-Grade Metamorphism of Clastic Rocks from the Meso-Neoproterozoic and the Paleozoic along the Profile Yueyang-Linxiang in Northeastern Hunan Province and Its Geological Implications

This study uses illite crystallinity, chlorite crystallinity, illite polytypes, the b_0 cell-dimension of K-white mica, clay mineral assemblages and mineral geothermo-geobarometers to investigate the overprint of diagenesis and metamorphism on the Meso-Neoproterozoic and the Lower Paleozoic along the profile Yueyang-Linxiang in northeastern Hunan Province, China. Illite crystallinity Kübler index (KI) of the <2μm fractions ranges from 0.225 to 0.485°?2θ while chlorite crystallinity árkai index (AI)ranges from 0.244 to 1.500°?2θ. This indicates that the Meso-Neoproterozoic and the Lower Paleozoic along the profile Yueyang-Linxiang were overprinted with diagenesis and anchi- to epimetamorphism. Peak metamorphic temperature is estimated with the IV site chlorite geothermometer roughly at 360°C. The b_0 cell dimension values of illites (K-mica) range from 0.9002 to 0.9054 nm and, on average, at 0.9030 nm for the Meso-Neoproterozoic. Based on cumulative frequency curves of illite (K-mica) b_0 cell dimension, the peak metamorphic pressure of the Meso-Neoproterozoic along the profile Yueyang-Linxiang is derived of an intermediate pressure type. Most illites occur in the 2M_1 polytype and some of them in a mixture of 2M_1+1M types especially those in the Paleozoic. This result partly agrees with the conclusion of the lower greenschist and greenschist facies of the Lengjiaxi and Banxi Groups. However, it is not agreed with the sedimentary cover from the Sinian to the Lower Paleozoic or from the Banxi Group to the Lower Paleozoic. Crustal thickening due to "collision" between the Yangtze and Cathaysia blocks led to an increase in the thickness of the Meso-Neoproterozoic to ca. 14 km and resulted in a temperature increase in those rocks due to burial. The very low grade to low grade metamorphism overprinting the Meso-Neoproterozoic implies that the so called “Chiangnania or Jiangnan orogen"was no relative with the “Grenvillian orogeney;instead,it might be a continuous amalgamation product between the Yangtze and Cathaysia blocks.
Geology and Isotope Geochemistry of the Yinchanggou-Qiluogou Pb-Zn Deposit, Sichuan Province, Southwest China

The Yinchanggou-Qiluogou Pb-Zn deposit, located in the western Yangtze Block, southwest China, is hosted by the Upper Sinian Dengying Formation dolostone. Ore bodies occur in the Qiluogou anticline and the NS- and NNW-trending faults. Sulfide ores mainly consist of sphalerite, pyrite, galena and calcite, with subordinate dolomite and quartz. Seventeen ore bodies have been discovered to date and they have a combined 1.0 million tons of sulfide ores with average grades of 2.27wt% Zn and 6.89wt% Pb. The δD_(H2O)-smow and δ~(18)OH_2O-SMOW values of fluid inclusions in quartz and calcite samples range from -68.9‰ to -48.7‰ and 7.3‰ to 15.9‰, respectively, suggesting that H_2O in the hydrothermal fluids sourced from metamorphic water. Calcite samples have δ~(13)C_(PDB) values ranging from -6.2‰ to -4.1‰ and ‰~(18)O_(SMOW) values ranging from 15.1‰ to 17.4‰, indicating C and O in the hydrothermal fluids likely derived from a mixed source of metamorphic fluids and the host carbonates. The δ~(34)S_(CDT) values of sulfide minerals range from 5.5‰ to 20.3‰, suggesting that thermal chemical reduction of sulfate minerals in evaporates were the most probable source of S in the hydrothermal fluids. The ~(206)Pb/~(204)Pb, ~(207)Pb/~(204)Pb and ~(208)Pb/~(204)Pb ratios of sulfide minerals fall in the range of 18.11 to 18.40, 15.66 to 15.76 and 38.25 to 38.88,respectively. The Pb isotopic data of the studied deposit plot near the upper crust Pb evolution curve and overlap with the age-corrected Proterozoic basement rocks and the Upper Sinian Dengying Formation hosting dolostone. This indicates that the Pb originated from a mixed source of the basement metamorphic rocks and the ore-hosting carbonate rocks. The ore geology and C-H-O-S-Pb isotopic data suggest that the Yinchanggou-Qiluogou deposit is an unusual carbonate-hosted, strata-bound and epigenetic deposit that derived ore-forming materials from a mixed source of the underlying Porterozoic basements and the Sinian hosting carbonates.
Early Cretaceous Magma Mingling in Xiaocuo,Southeastern China Continental Margin: Implications for Subduction of Paleo-Pacific Plate

Magma mingling has been identified within the continental margin of southeastern China. This study focuses on the relationship between mafic and felsic igneous rocks in composite dikes and plutons in this area, and uses this relationship to examine the tectonic and geodynamic implications of the mingling of mafic and felsic magmas. Mafic magmatic enclaves (MMEs) show complex relationships with the hosting Xiaocuo granite in Fujian area, including lenticular to rounded porphyritic microgranular enclaves containing abundant felsic/mafic phenocrysts, elongate mafic enclaves, and back-veining of the felsic host granite into mafic enclaves. LA-ICP-MS zircon U-Pb analyses show crystallization of the granite and dioritic mafic magmatic enclave during ca. 132 and 116 Ma. The host granite and MMEs both show zircon growth during repeated thermal events at ?210 Ma and 160-180 Ma. Samples from the magma mingling zone generally contain felsic-derived zircons with well-developed growth zoning and aspect ratios of 2-3,and mafic-derived zircons with no obvious oscillatory zoning and with higher aspect ratios of 5-10. However, these two groups of zircons show no obvious trace element or age differences. The Hf-isotope compositions show that the host granite and MMEs have similar ε_(Hf)(t) values from negative to positive which suggest a mixed source from partial melting of the Meso-Neoproterozoic with involvement of enriched mantle-derived magmas or juvenile components. The lithologies, mineral associations, and geochemical characteristics of the mafic and felsic rocks in this study area indicate that both were intruded together, suggesting Early Cretaceous mantle-crustal interactions along the southeastern China continental margin. The Early Cretaceous magma mingling is correlated to subduction of Paleo-Pacific plate.
脾窦岸细胞瘤1例

脾窦岸细胞瘤(littoral cell angioma,LCA)在临床上属于一种原发性脾血管瘤,多发于正常的脾红髓窦岸细胞,属于网状内皮细胞系统,该细胞的特点是内皮细胞和组织细胞相关抗原能够同时强表达,显示了双重分化的特征;而正常的脾红髓窦岸细胞仅内皮细胞标记物阳性。LCA是由Falk在1991年首次报道并命名,此种病例十分罕见且文献多为个案报道,目前国内外报道不足170例。天津医科大学肿瘤医院肝胆肿瘤科于2016年3月收治1例脾窦岸细胞瘤患者,患者男性,46岁。因查体发现腹腔肿物1周入院。