mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Mapping and ultrastructure of antennal chemosensilla of the wheat bug Eurygaster maura

Antennae of the wheat stink bug Eurygaster maura L. (Hemiptera: Scutelleridae) were investigated to elucidate structure and distribution of antennal chemosensilla in females. Five type of sensilla were identified and characterized using a scanning electron microscope (SEM) and a transmission electron microscope (TEM). Type 1 sensilla are mechanical and contact chemoreceptors with a single apical pore. Types 2 and 3 sensilla are multiporous chemoreceptors both with typical features of olfactory sensilla. Type 4 are multiporous peg-like sensilla, short and with a grooved surface. Type 5 are sensilla coeloconica with a smooth and aporous peg completely inserted in a sub-cuticular chamber. All types are distributed on the two flagellar segments, but we considered only the apical flagellomere in which the largest number of sensilla are located. The most abundant sensilla are type 3, while the less numerous are type 5. All types, except type 2, decreased in number from the tip to the base of the segment. The lower density of sensilla was recorded on the dorsal-internal part of the apical antennomere, while the higher density was recorded on the opposite side (extemal-ventral).
内质网应激:肥胖与胰岛素抵抗/炎症之间的另一联系?

肥胖在美国已成流行病,肥胖同时也在全球增加.肥胖与胰岛素抵抗(IR)(周围和肝脏)及低度炎症状态密切相关,后者特点是组织内促炎细胞因子增高.
以急性青光眼发作为主征的青-睫综合征一例

梁×× 女 56岁.左眼痛伴头痛,视物不清10d.于2008年12月28日突然感到左眼痛伴头痛,第二天眼痛加重,视物模糊,恶心出现虹视、羞明等症状.检查视力:右1.0,左0.5,右眼未见异常.左眼球结膜混合性充血,角膜高度水肿,呈雾状混浊,前房不浅,房闪(-),角膜后有大量灰白色大小不等的KP,位于下方,呈弥漫状.
Goldenhar综合征一例

患者女 16岁.于2008年7月2日入院,生后发现右眼颞侧有黄白色肿物,伴有双耳屏前小肿物,右侧口角开裂及下1/3面部发育畸形.患者系第一胎,32周早产,母孕1月左右有发烧史,因不知怀孕,服用抗生素及其他药物治疗(四环素、土霉素,服用5d左右),父母非近亲婚配,家族中无类似患者.2岁时切除右侧副耳,并缝合开裂的右侧口角.
荧光眼底血管造影中血管迷走性晕厥三例

例1 男 19岁.因右眼前黑影飘动半月就诊.既往体健,右眼视力0.8,矫正不应,左眼视力1.0,右眼前节无异常,右眼玻璃体腔内见少许棕褐色浮游物,颞侧周边静脉血管见白鞘.门诊诊断:右眼视网膜静脉周围炎,建议行荧光眼底血管造影.
视网膜中央动脉阻塞继发新生血管性青光眼一例

患者 女 78岁 主因右眼视力突然下降15h,于2008年8月18日入院.患者于2008年8月17日晚约7h许,无明显诱因出现右眼视力突然丧失,无明显头痛、眼胀、眼痛等伴症,外院就诊,诊为右眼视网膜中央动脉阻塞,予硝酸甘油片舌下含服,吸氧、眼球按摩,2%美开朗眼药水局部滴眼及静脉点滴血塞通、20%甘露醇治疗,眼症无明显改善,于次日来我院眼科门诊就诊,以右眼视网膜中央动脉阻塞收入院.既往高脂血症病史3年,糖尿病病史3年,均未系统用药.否认冠心病、高血压等其他慢性全身病史.
瞳孔残膜手术治疗一例

患者 男 15岁 左眼视力障碍10年,偏斜2年,未曾诊治.视力:右眼1.0,左眼0.04,左眼球向各方向运动自如.角膜映光检查,左眼向颞侧偏斜,双眼角膜透明,前房深浅正常.左眼瞳孔区有与虹膜相同之膜状物,周围与虹膜皱环相连,偏上方有两个小孔.
Avastin用于眼病治疗的新进展

Avastin(贝伐单抗)是一类全长、人源化的重组鼠单克隆抗体,2004年被美国食品药品管理局(FDA)批准上市.最初作为一种血管内皮生长因子(VEGF)抑制剂来治疗实体肿瘤,后被用于治疗眼科疾病,包括:老年性黄斑变性(AMD)引起的脉络膜下新生血管(CNV),糖尿病性视网膜病变,黄斑囊样水肿(CME),病理性近视引起的CNV,新生血管性青光眼等.但尚处于临床试验阶段,目前已显示出良好的疗效.近年来,国外就Avastin在眼科的治疗已取得一定的进展,此文现综述如下.
脂联素与结肠直肠肿瘤相关性研究进展

结肠直肠肿瘤是消化系统常见病,其发病率逐年上升.近年研究认为脂联素是脂肪细胞特异分泌的生物活性因子,与几种肥胖相关性肿瘤的关系越来越受到人们的关注.以下对脂联素与结肠直肠肿瘤的相关性作一综述,希望能为结肠直肠肿瘤的防治提供新的思路和方法.
大连地区急性心肌梗死发病12 h内入院诊疗状况分析

急性ST段抬高型心肌梗死(STEMI)是急性冠脉综合征中病死率和致残率最高的一种,药物再灌注治疗及急诊介入治疗仍然是STEMI主要治疗策略[1].近期研究发现,急诊经皮冠状动脉介入治疗的时间与急性STEMI患者1年病死率相关[2].本研究通过分析发病12 h内就诊的急性STEMI患者住院治疗情况,评价大连地区急性STEMI患者治疗状况.
新生儿Mur溶血病1例

患儿女,50 h.因皮肤黄染1 d于2008-08-08入院.患儿系第2胎第2产,胎龄38周.生后24 h内出现皮肤黄染进行性加重.母亲8年前产1男婴,身体健康,无输血史.入院查体:生命体征平稳,反应好,全身皮肤重度黄染,巩膜黄染,心肺无异常,腹软,肝肋下1.5 cm,脾肋下未扪及,四肢肌张力正常.实验室检查:血常规:白细胞8.4×10~9/L(中性细胞0.65,淋巴细胞0.27),红细胞2.76×10~(12)/L,(网织红细胞0.074) ,血红蛋白98 g/L,血小板331×10~9/L.
毛细支气管炎的诊治进展

毛细支气管炎是婴幼儿较常见的一种下呼吸道感染性疾病,临床卜以下呼吸道梗阻所敛的喘憋为特征~([1]).现对毛细支气管炎的病原、机制、治疗综述如下.1 毛细支气管炎的流行病学及病因学
诱导痰液技术及其在哮喘临床研究中的作用

通过非创伤性途径评价和监测气道炎症是当前哮喘研究的热点.1992年Pin等~([1])首次将雾化吸入高渗盐水诱导痰液用于哮喘研究.认为其具有安全无创、简单易行的特点.此后受到越来越多的重视.
舍曲林戒断综合征1例

1 资料患者,25岁,女,主诉发作性胸痛、气喘、心跳快、要晕倒1年,于2007年2月26日在南京脑科医院诊断为惊恐障碍,服舍曲林(商品名:左洛复,辉瑞公司生产)50 mg早,至2007年8月期间,自行减量为25 mg早,至2008年11月18日停用舍曲林,停药后3～4 d开始出现异常,具体表现为:做噩梦,周身不能动弹,象是被人压着,喊不出来;同时,每晚出现下颌和唇周有电击感,每次发作1～2 s,仅在晚间发作(10～20次/d);另外,感到发作性的心脏跳到喉咙口,象是从高空落下时的感觉一样.
异尖线虫过敏原研究进展

异尖线虫(Anisakis spp.) 幼虫是重要的人兽共患寄生虫病病原体,呈世界性分布,为我国禁止入境的二类寄生虫.引起异尖线虫病的主要病原体为简单异尖线虫复合种A. simplex complex,包括3个姊妹种(简单异尖线虫A. simplex s. s.;派氏异尖线虫A. pegreffii和简单异尖线虫C型 A. complex C).已有的研究报道显示,日本的异尖线虫病主要是由简单异尖线虫引起的;而欧洲的异尖线虫病主要由派氏异尖线虫引起的.人食入寄生在海鱼体内的异尖线虫Ⅲ期幼虫可引起异尖线虫病(anisakiasis),典型的异尖线虫病为恶心,呕吐,腹痛,腹泻等,感染了异尖线虫会使免疫系统TH2亚群活化,从而产生大量的IgE抗体~([1]).另外一种临床上的情况为过敏反应,由于病人对线虫过敏原的再次接触就会大大增加IgE介导的过敏反应,可由风疹转化为危及生命的过敏性休克~([2-6]).以下主要对致病性异尖线虫过敏原的研究进展作一综述.
银屑病皮损中CXCL11/I-TAC及其受体CXCR3的表达

CXCL11/I-TAC(Interferon-inducible T Cell α-chemoattractant)是一种Ⅰ型趋化因子,可以特异性地趋化表达CXCR3的Th1细胞[1,2].有研究表明,Th1占主导的皮肤病如银屑病皮损中,CXCL11/I-TAC mRNA主要在基底层角质形成细胞中高表达;CXCR3主要表达于真皮炎症区大部分T细胞[3],提示CXCL11/I-TAC及其受体CXCR3在该类慢性炎症性皮肤病的T细胞浸润的募集和维持中起重要作用.Th1细胞因子IFN-γ和TNF-α在Th1型皮肤病皮损中也高表达[4,5].
D-半乳糖致衰老小鼠学习记忆行为改变及对海马神经发生的影响

目的 探讨D-半乳糖衰老模型小鼠学习记忆行为变化及对海马齿状回细胞增殖的影响.方法 采用连续皮下注射D-半乳糖构建亚急性衰老小鼠模型,用Y-电迷宫检测衰老小鼠的学习记忆情况,并于造模完成前7 d腹腔内注射5-溴脱氧尿嘧啶核苷(BrdU),行为检测完成后,取海马脑块行常规石蜡包埋,冠状连续切片,采用免疫组化法检测齿状回BrdU阳性细胞并计数.结果 衰老模型小鼠呈现明显的学习记忆减退,其齿状回增殖细胞数量与正常衰老相近.结论 采用连续皮下注射D-半乳糖可成功构建衰老模型,其学习记忆障碍可能与齿状回细胞增殖抑制有关.
胸腔内灌注顺铂联合胸部热疗治疗老年恶性胸水临床观察

本文用热疗联合胸腔内灌注顺铂治疗老年恶性胸水31例,取得了满意的疗效.1 临床资料1.1 一般资料 2000年9月至2007年6月收治晚期肿瘤致胸腔积液老年患者62例,男33例,女29例,年龄61～83岁,平均年龄66.8岁.
公寓老年人交往需求的调查

目的 评估老年公寓老年人心理状况、交往需求状况,为公寓老年人交往、心理护理提供科学依据.方法 应用问卷法和会谈法,对广西重阳老年公寓颐养园122例老年人进行调查,有效问卷118份.结果 老年人22.47%有焦虑、孤独和沮丧,其发生与性别、年龄、文化程度、有偶与否、患慢性病种数、运动方式有关;81.36%希望与更多人进行交往,66.95%希望有志愿者陪其聊天,67.80%希望家人经常探望.结论 老年公寓的老年人存在不同程度的心身健康问题,交往需求高却不能完全自行解决.
Muc-1 mRNA和CD44 mRNA在非小细胞肺癌组织中的表达及与预后的关系

目的 探讨Muc-1 mRNA和CD44 mRNA在非小细胞肺癌(NSCLC)组织中的表达情况与淋巴结转移的相关性及其与预后的关系.方法 应用RT-PCR方法检测36例NSCLC组织中和10例正常肺组织中Muc-1 mRNA和CD44 mRNA的表达情况.结果 ① 36例NSCLC组织中有19例Muc-1 mRNA阳性表达,阳性表达率为52.7%;21例CD44 mRNA表达,阳性表达率为58.3%.②Muc-1 mRNA在NSCLC组织中的阳性表达与患者的年龄、性别、组织学类型、TNM分期、肿瘤大小无关(P＞0.05),与淋巴结转移有关(χ~2 =10.166,P＜0.05);CD44 mRNA在NSCLC组织中的阳性表达与患者的年龄、性别、组织学类型、TNM分期、肿瘤大小无关(P＞0.05),与淋巴结转移有关(χ2=8.371,P＜0.05).③Muc-1 mRNA和 CD44 mRNA阳性表达与NSCLC患者的预后有关(P＜0.05).④Muc-1 mRNA和CD44 mRNA在NSCLC组织中表达成正相关(r=0.442,P＜0.05).结论 Muc-1 mRNA和 CD44 mRNA阳性表达的NSCLC患者淋巴结转移率高,对NSCLC患者预后判断具有一定的指导作用.
选择起搏位置优化起搏治疗效果

目前改变起搏位置使起搏更接近生理性成为研究热点,维持正常的心室肌激动收缩顺序是目前临床起搏方面的难题,即使是DDD起搏器,虽然保持了正常的心脏房室收缩顺序,但不能维持正常的心室肌激动顺序和左右心室收缩同步性,从而产生一系列异常的血流动力学改变,最终导致心排出量降低.
内皮素、血管紧张素Ⅱ、转化生长因子β1与心肌肥厚关系的研究进展

心肌肥厚使心血管意外事件如猝死、心肌梗死、心律失常、心衰等发生率显著增加.心肌肥厚包括心肌细胞及细胞外基质的增多,除血流动力学因素外许多社经体液因子及血管活性肽也参与了其过程.
XPD基因遗传多态性与晚期结直肠癌患者对铂类药物敏感性关系的研究

目的 探讨核苷酸切除修复系统基因XPD遗传多态性与晚期结直肠癌(CRC)患者对铂类药物化疗敏感性的关系.方法 对晚期CRC患者96例进行含奥沙利铂的联合化疗,以影像学方法判定其疗效.在治疗前抽血检测XPD Asp312Asn和XPD Lys751Gln基因多态性,比较不同基因型患者的化疗敏感性.结果 患者化疗后部分缓解(PR)20例,稳定(SD)59例,进展(PD)17例,有效率(RR)为20.8%.多因素分析表明,携带Gln/Gln基因型患者的疾病进展风险是至少携带一个Lys等位基因(Lys/Lys和Lys/Gln基因型)个体的7.8倍(OR＝7.813,95% CI=1.834-33.277,P＜0.05),但未观察到XPD Asp312Asn多态与化疗敏感性相关,未发现XPD基因多态在影响铂类药敏感性中存在联合作用.结论 XPD基因遗传多态与晚期CRC对铂类化疗的敏感性相关.
全脊柱融合1例

在百余套脊柱骨骼标本中,发现1例全脊柱椎骨融合为一整体,按骨骼人类学性别、年龄鉴定标准[1](颅骨和骨盆均有且配套)及法医学鉴定标准[2],鉴定出此例标本为成年女性,报道如下:
航道附近的海洋环境噪声场模型

对青岛海域长时间观测的海洋环境噪声数据进行了水平相关特性分析.结果发现,用已有海洋环境噪声模型无法解释实验水平相关变化特性.究其原因,已有海洋环境噪声模型假设噪声源海面均匀分布,没考虑附近离散船噪声的影响,而实验海域位于航道附近,过往的船只较多.在已有海面噪声场模型的基础上,提出航道附近的海洋环境噪声模型,使得空间任意两点间的噪声场互谱密度既考虑海面均匀分布噪声源,也考虑附近离散分布船噪声的影响.新的海洋环境噪声模型可很好地解释实验水平相关特性.
聚乙二醇溶液中声速与溶质分子量关系的实验研究

本实验利用超声光栅测量了乙二醇单体和分子量为200,600,2000,10000的聚乙二醇溶液的声速,检验了声速与溶质分子量的关系,验证了在糖溶液中溶质分子质量越大声速越小的Parthasarathy经验规律.但是发现Panhasarathy经验规律在聚乙二醇溶液中的失效.尝试利用Flory-Krigbaum的"链段云"模型给出了初步的解释.
MOCVD growth of AlGaInP/GaInP quantum well laser diode with asymmetric cladding structure for high power applications

In order to improve the characteristics of the general broad-waveguide 808-nm semiconductor laser diode (LD),we design a new type quantum well LD with an asymmetric cladding structure. The structure is grown by metal organic chemical vapor deposition (MOCVD).For the devices with 100-μm-wide stripe and 1000-μm-long cavity under continuous-wave (CW) operation condition, the typical threshold current is 190 mA, the slope efficiency is 1.31 W/A, the wall-plug efficiency reaches 63%,and the maximum output power reaches higher than 7 W. And the internal absorption value decreases to 1.5 cm~(-1).
Highly Efficient Conjugate Addition of Amines to Electron Deficient Alkenes Catalyzed by KF Supported on Metal Oxides

A novel efficient procedure has been developed for the conjugate addition of amines to electron deficient al-kenes. A series of KF supported on different carriers have been synthesized for the conjugate addition amines to al- kenes. After optimizing the reaction conditions, KF/MgO was chosen as the most efficient catalyst for the reactions. The results showed that the catalyst was very efficient for the conjugate addition of amines to electron deficient al-kenes with excellent yields in several minutes. Operational simplicity, no need of any solvent, low cost of the catalyst used, high yields, reusability, excellent chemoselectivity and wide applicability are the key features of this methodology.
Study of the Reactions of Fluorine-Containing Amides with Aldehydes and the Structures of the Bisamides

The reactions of trifluoro or bromodifluoro acetamides with aromatic aldehydes in the presence of thionyl chlo-ride and trifluoromethylsulfonic acid were investigated.Compared with the procedure reported previously, the yields were improved greatly and the reaction conditions were much milder.Both intra- and intermolecular weak interactions were discussed in detail based on the X-ray diffraction analysis of 3aa and 3ab.
Polymer-Controlled Growth of CuO Nanodiscs in the Mild Aqueous Solution

CuO nanodiscs have been synthesized on a large scale by a facile solution-based method using polymers as crystal growth modifiers.X-ray powder diffraction (XRD), scanning electron microscopy (SEM) and high resolu-tion transmission electron microscopy (HRTEM) were carded out to characterize the structures and morphologies of the obtained products.The effects of reaction temperature, concentrations of polyacrylamide (PAM) and reac-tants on the morphology and size of the product were studied.The results revealed that the CuO nanodisc had sin-gle-crystal monoclinic structures, and grew along (002) and (110) planes.Experimental conditions had all influence on the shape and size of the final products, but polymer PAM played the key role in formation of the CuO nanodisc.A possible growth mechanism of the CuO nanostructures based on typical polymer-crystal interactions in a mild aqueous solution was given.Polymer-directed crystal growth may provide promising routes to rational synthesis of various ordered inorganic and inorganic-organic hybrid materials with complex forms and structural specialization.
Synthesis and Bioactivity of Some New 2-(Alkoxy carbonyl alkyl)-6-bromo-3,4-dihydro-3-(α-methyl benzyl)-2-oxobenzo[e][2H-1,3,2-oxazaphosphinine]Derivatives

Synthesis of some new 2-(alkoxy carbonyl alkyl)-6-bromo-3,4-dihydro-3-(α-methyl benzyl)-2-oxo-3-benzo[e][2H-1,3,2-oxazaphosphinine]derivatives was accomplished through a two step process,which involves the condensation of 2-[(α-methylbenzyl amino)methyl]-4-bromophenol (1) with phosphorus oxychloride in equimolar quantities in the presence of triethylamine in dry toluene in 50-55 ℃ producing the corresponding intermediate (2),and subsequent reaction with the amino acid alkyl ester in dry tetrahydrofuran in the presence of triethylamine at different temperatures.They exhibited significant antibacterial and fungal activity.
An Efficient Four-Component,One-Pot Synthesis of Poly-Substituted Pyrimidines in Water

An efficient environmentally friendly synthesis of poly-substituted pyrimidines has been developed via a four-component,one-pot reaction of malononitrile,carbon disulfide,alkyl halide and S-alkylisothiouronium salt in water at room temperature.Water as solvent,mild reaction conditions,short reaction time,simple experimental procedures,broad scope of substrates and good yields are the main advantages of this method.
Synthesis and Electrochemical Performance of Ti~(4+) Doped LiV_3O_8

Layered LiTi_yV_(3-0.8y)O_8 cathode materials with y=0,0.04, 0.06, 0.08 were prepared by a sol-gel process fol-lowing a calcination at 350 ℃ in air for 16 h, and show differences in morphological properties (shape, particle size and specific surface area) and electrochemical properties (first charge profile, reversible capacity and rate capabil- ity). The LiTi_yV_(3-0.8y)O_8 powders were characterized by means of X-ray diffraction (XRD), charge/discharge cycling, cyclic voltammetry (CV), and scanning electron microscopy (SEM). LiTi_yV_(3-0.8y)O_8 was crystallized to a well lay-ered structure. Its initial specific discharge capacity was higher than that of pristine material. When y=0.04, the sample showed the highest initial discharge capacity of 348.9 mAh·g~1 at a current density of 60 mA·g~(-1) in the voltage range 1.8-4.0 V, and also higher discharge capacity and better cycle ability.
Silver Nanowire Film: Green Synthesis and Its Surface Enhanced Raman Scattering

One-step preparation of silver nanowires on the silicon wafer has been performed successfully employing silver nitrate as silver source. The procedure was operated at room temperature employing an environmentally benign compound of ethylene glycol as reductive agent, which is a completely green route. The as-prepared products were characterized with X-ray diffraction, scanning electron microscopy and energy dispersive X-ray spectrum, which reveals uniform silver nanowires with average diameter of 20 nm. These silver nanowires were used to detect Rho-damine 6G via surface-enhanced Raman scattering. The characteristic peaks appeared when the concentration of Rhodamine 6G was 10 nmol·L~(-1).
Development and Validation of Selective Spectrophotometric Methods for the Determination of Pregabalin in Pharmaceutical Preparation

Three simple,quick and sensitive methods are described for the spectrophotometric determination of pregabalin (Pgb) in pharmaceutical preparations.Among them,the first two methods are based on the reaction of Pgb as n-electron donors with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and 7,7,8,8-tetracyanoquinodimethane (TCNQ) as π-acceptors to give highly colored complex species.The colored products were quantitated spectrophotometrically at 494 and 841 nm for DDQ and TCNQ,respectively.Optimization of the different experimental conditions was conducted.Beer's law was obeyed in the concentration ranges 2.0-30.0 and 1.5-10 μg·mL~(-1) for DDQ and TCNQ methods,respectively.The third method is based on the interaction of ninhydrin (NN) with primary amine present in the pregabaline.This reaction produces a blue coloured product in N,N-dimethylformamide (DMF) medium,which absorbs maximally at 573 nm.Beer's law was found in the concentration range 40.0-180.0 μg·mL~(-1).The methods were applied successfully to the determination of this drug in pharmaceutical dosage forms.
Non-isothermal Decomposition Kinetics,Specific Heat Capacity and Adiabatic Time-to-explosion of 1-Amino-1-hydrazino-2,2-dinitroethylene (AHDNE)

The thermal behavior and non-isothermal kinetics of the exothermic decomposition reaction of 1-amino-1-hydrazino-2,2-dinitroethylene (AHDNE) were studied with DSC and TG/DTG methods.The kinetic equation obtained is dα/dT=10~(19.29)(1-α)exp(-1.88×10~4/T)/β.The critical temperature of thermal explosion is 98.16 ℃.The specific heat capacity of AHDNE was determined,and the standard molar specific heat capacity is 211.86 J·mol~(-1)·K~(-1) at 298.15 K.The adiabatic time-to-explosion of AHDNE was also calculated to be 59.21 s.AHDNE is unstable and has much lower thermostability than 1,1-diamino-2,2-dinitroethylene (FOX-7).
Synthesis of Dinaphtho-dioxaphosphepin-4-oxides, Epoxides and Bisphosphonates

A few new seven-membered phosphorus heterocyclic compounds and bis-phosphonates (5a-5g, 5f, 5g', 9 and 10) were prepared by the reaction of 4-bromo dioxaphosphepin (2) with various Grignard reagents followed by their oxidation with H_2O_2. All the compounds were thoroughly characterized by elemental analysis, IR,~1H, ℃, ~(31)PNMR and mass spectral data. Their antimicrobial activity was evaluated and some of them possess significant activity.
Asymmetric Alkynylation of Aldehydes Catalyzed by Bifunctional Zinc(salen) Complex

The asymmetric alkynylation of aldehydes catalyzed by bifunctional Zn(salen) catalyst was realized. With a Kozlowski salen ligand (7e) bearing secondary basic 1-piperidinylmethyl groups at C-3 and C-3', the enhanced catalytic reactivity and stereoselectivity in comparison with that of normal salen ligands in the alkynylzinc addition to aldehydes were observed.
Highly Selective Perchlorate Membrane Electrode Based on Cobalt(Ⅲ) Schiff Base as a Neutral Carrier

A highly selective poly(vinyl chloride) (PVC) membrane electrode based on Co(Ⅲ)-Schiff base [Co(5-NO_2-Salen)(PBu_3)]ClO_4·H_2O (where 5-NO_2-SalenH=bis(5-nitrosalycilaldehyde)ethylenediamine) as a new carrier for construction of perchlorate-selective electrode by incorporating the membrane ingredients on the surface of a graphite electrodes has been reported. The proposed electrode possesses a very wide Nernestian potential linear range to perchlorate from 1.0×10~5 to 5.0×10~(-1) mol·L~(-1) with a slope of (59.4±0.9) mV per decade of perchlo-rate concentration with a low detection limit of 5.0× 10~(-7) mol·L~(-1) and good perchlorate selectivity over the wide variety of other anions. The developed electrode has an especially fast response (<5 s) and a wide pH independent range (3.0-12.0) in comparison with recent reported electrodes and can be used for at least 2 months without any considerable divergence in their potential response. This electrode was used for the determination of perchlorate in river water, drinking water, sludgy water and human urine with satisfactory results without complicated and time consuming pretreatment.
彩色多普勒超声诊断从腹主动脉至髂内动脉多发性动脉瘤1例

患者男,78岁.体瘦,高血压史10余年.气喘夜间加剧不能平卧,临床以支气管哮喘收住入院.行腹部常规检查至膀胱上方见梅花状囊性包块,彩色多普勒示囊性包块内五彩相间的血流信号.由此行腹主动脉检查,使用MyLab90超声诊断仪,凸阵探头,频率3.5 MHz.声像图表现:腹主动脉近分叉段见2处梭形扩张,近心端1处稍大,直径3.4 cm,远侧端1处稍小, 直径2.6 cm.
Data Driven Fault Diagnosis and Fault Tolerant Control: Some Advances and Possible New Directions

This paper presents a selected survey covering the advances of fault diagnosis and fault tolerant control using data driven techniques. A brief summary of the general developments in fault detection and diagnosis for industrial processes is given, which is then followed by discussions on the widely used data driven and knowledge-based techniques. A successful application example is also given, which deals with faults caused by the misplacement of control loop set points and several areas of potential future directions are included in the paper.
Human sperm quality and lipid content after migration into normal ovulatory human cervical mucus containing low numbers of leukocytes

The aim of this study was to investigate whether a relationship exists between the presence of low number of leukocytes in normal ovulatory cervical mucus and sperm quality and lipid content after migration. The percentages of live,motile and morphologically normal spermatozoa,movement parameters assessed by computer-aided sperm analysis(CASA),and ionophore-induced acrosome reaction measured by flow cytometry were determined before and after migration. High-performance liquid chromatography with ultraviolet detection was used to measure the sperm lipid content,including the various diacyl subspecies. The number of leukocytes found in solubilized mucus samples was counted using a haemocytometric method. Overall,the presence of leukocytes in the cervical mucus samples did not significantly influence sperm motility and morphology,sperm kinematic parameters,or the sperm content in sphingomyelin or cholesterol. In contrast,after migration,the decrease in various sperm diacyls and the level of induced acrosome reaction was significantly less pronounced in mucus samples containing ≥ 10~4 leukocytes than in mucus samples with no or rare leukocytes whereas the level of induced acrosome reaction was higher. The present data suggest that the low level of leukocytes found in normal ovulatory cervical mucus could influence the process of sperm lipid remodelling/capacitation.
视盘毛细血管瘤合并视网膜毛细血管瘤及视网膜前膜一例

视盘毛细血管瘤由外有结缔组织的毛细血管团和管径不均匀的扩张血管构成,发病率为1:10000～1:22000,而同时合并视网膜毛细血管瘤者更为罕见.现将1例典型病例报告如下.患者,男,33岁.因发现左眼视力下降、视物变形半个月于2008年6月4日前往解放军总医院就诊.否认家族性眼病史、脑病史及肿瘤病史.视力:右眼1.0,左眼0.2.双眼前节未见明显异常,右眼眼底未见明显异常.左眼视盘鼻下方可见一约2PD大小橘红色肿物,轻度隆起,表面光滑,边界清楚(图1).瘤体鼻侧及下方可见局限性渗出性视网膜脱离,下方较明显,黄斑颞上方2PD处可见约1/2PD大小橘红色肿物.后极部可见大范围致密视网膜前膜,部分遮挡并牵拉黄斑周围的视网膜血管.
Centrifugal casting processes of manufacturing in situ functionally gradient composite materials of Al-19Si-5Mg alloy

Cylindrical components of in situ functionally gradient composite materials of Al-19Si-5Mg alloy were manufactured by centrifugal casting. Microstructure characteristics of the manufactured components were observed and the effects of the used process factors on these characteristics were analyzed. The results of observations shows that, in thickness, the components possess microstructures accumulating lots of Mg_2Si particles and a portion of primary silicon particles in the inner layer, a little Mg_2Si and primary silicon particles in the outer layer, and without any Mg_2Si and primary silicon particle in the middle layer. The results of the analysis indicate that the rotation rate of centrifugal casting, mould temperature, and melt pouring temperature have evidently affected the accumulation of the second phase particles. Also, the higher the centrifugal rotation rate, mould temperature, and melt pouring temperature are, the more evident in the inner layer the degree of accumulation of Mg_2Si and primary silicon particles is.
Vancouver B型股骨假体周围骨折的手术治疗

随着髋关节置换手术的成熟,其在临床的应用范围越来越广,给髋关节骨性关节炎、股骨颈骨折以及髋关节发育不良等疾病患者带来了,福音.随着术后患者生存和随访时间的逐年延长,各种远期并发症也相继出现.
"5·12"汶川大地震的启示——创伤骨科与康复契机

2008年的汶川大地震,震级强度为里氏8.0级,造成了极大的人员伤亡,死亡人数接近7万,严重受伤人数亦高达7000,毁坏程度之大、受灾人数之多实在罕有.国家的及时救援行动,抢救了许许多多宝贵的生命,大大减少了死亡人数.但仍有不少的重症伤员需要长期的康复.
脑胶质瘤的中西医研究与治疗进展

脑胶质瘤占颅内肿瘤约40%～45%,是严重危害人类健康的疾病之一.脑胶质瘤主要分为星型细胞瘤、胶质母细胞瘤、少突胶质细胞瘤、髓斗母细胞瘤、室管膜瘤等,根据其恶性程度可分为4级,病理级别越高的肿瘤预后越差.脑恶性胶质瘤患者的平均生存期仅52周,是人类预后最差的肿瘤之一.
Regulation of gap-junction protein connexin 43 by β-adrenergic receptor stimulation in rat cardiomyocytes

Aim:β-adrenergic receptor (β-AR) agonists are among the most potent factors regulating cardiac electrophysiological properties.Connexin 43 (Cx43),the predominant gap-junction protein in the heart,has an indispensable role in modulating cardiac electric activities by affecting gap-junction function.The present study investigates the effects of short-term stimulation of β-AR subtypes on Cx43 expression and gap junction intercellular communication (GJIC) function.Methods:The level of Cx43 expression in neonatal rat cardiomyocytes (NRCM) was detected by a Western blotting assay.The GJIC function was evaluated by scrape loading/dye transfer assay.Results:Stimulation of β-AR by the agonist isoproterenol for 5 min induces the up-regulation of nonphosphorylated Cx43 protein level,but not total Cx43.Selective β_2-AR inhibitor ICI 118551,but not β-AR inhibitor CGP20712,could fully abolish the effect.Moreover,pretreatment with both protein kinase A inhibitor H89 and G,protein inhibitor pertussis toxin also inhibited the isoproterenol-induced increase of nonphosphorylated Cx43 expression.Isoproterenol-induced up-regulation of nonphosphorylated Cx43 is accompanied with enhanced GJIC function.Conclusion:Taken together,β_2-AR stimulation increases the expression of nonphosphorylated Cx43,thereby enhancing the gating function of gap junctions in cardiac myocytes in both a protein kinase A-and G_1-dependent manner.
Nicotine and inflammatory neurological disorders

Cigarette smoke is a major health risk factor which significantly increases the incidence of diseases including lung cancer and respiratory infections. However, there is increasing evidence that smokers have a lower incidence of some inflamma- tory and neurodegenerative diseases. Nicotine is the main immunosuppressive constituent of cigarette smoke, which inhib-its both the innate and adaptive immune responses. Unlike cigarette smoke, nicotine is not yet considered to be a carcino-gen and may, in fact, have therapeutic potential as a neuroprotective and anti-inflammatory agent. This review provides a synopsis summarizing the effects of nicotine on the immune system and its (nicotine) influences on various neurological diseases.