mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Promoting Effects of Pt on the Catalytic Performance of Supported NiB Amorphous Alloy Catalysts for Benzene Hydrogenation

A support(denoted AM)was prepared using pseudo-boehmite and mordenite.Ni-B and NiPtB amorphous catalysts were prepared on the support by the impregnation method followed by chemical reduction with a KBH4 solution.And the catalysts were characterized by X-ray diffraction(XRD),environment scanning electron microscope(ESEM),inductively coupled plasma(ICP),H2-temperature programmed reduction(H2-TPR),differential thermal analysis(DTA),and BET.Benzene hydrogenation was used as a probe reaction to evaluate the effect of addition of small quantities of Pt on the NiB/AM catalyst.The results show that Pt can promote the reduction of NiO and the formation of active sites,leading to smaller catalyst particles and better dispersion of active metal particles on the support.The catalytic activity,sulfur resistance and thermal stability were remarkably improved by Pt doping of the NiB/AM catalyst.
叶间动脉血流动力学参数联合血清胱抑素C对原发性高血压肾病的早期诊断价值

近年来的研究结果表明,原发性高血压初期即可引起肾小动脉痉挛、肾血流量降低等肾损害的早期改变~([1])。本研究应用彩色多普勒超声对原发性高血压患者叶间动脉血流动力学参数进行检测,分析叶间动脉阻力指数(RI)变化规律,联合实验室敏感指标血清胱抑素C(serum cystatin C,Scys C),探讨彩色多普勒超声对原发性高血压早期肾损害的诊断价值。[取自正文]
新资源食品———元宝枫籽油

为了促进木本油料元宝枫资源的开发利用，对元宝枫籽油的开发历史、特性及制取方法进行了介绍。元宝枫籽油含有功能性脂肪酸神经酸、高含量维生素E，具有抗菌、抗肿瘤等作用，目前已被卫生部批准为新资源食品，随着人们对元宝枫籽油认识的深入，其必然会得到快速发展。
Characteristic of Local Boiling Heat Transfer of Ammonia and Ammonia/Water Binary Mixture on the Plate Type Evaporator

Power generation using small temperature difference such as ocean thermal energy conversion(OTEC)and discharged thermal energy conversion(DTEC)is expected to be the countermeasures against global warming problem.As ammonia and ammonia/water are used in evaporators for OTEC and DTEC as working fluids,the research of their local boiling heat transfer is important for improvement of the power generation efficiency.Measurements of local boiling heat transfer coefficients were performed for ammonia/water mixture(z=0.9-1)on a vertical flat plate heat exchanger in a range of mass flux(7.5-15 kg/m~2s),heat flux(15-23 kW/m~2),and pressure (0.7-0.9 MPa).The result shows that in the case of ammonia/water mixture,the local heat transfer coefficients increase with an increase of mass flux and composition of ammonia,and decrease with an increase of heat flux．
Unsteady Flow at Low Flow-rate Region in a Semi-open Propeller Fan(Velocity Fluctuation outside of Blade Tip)

In order to clarify the unsteady flow fields at low flow-rate region with positive gradient on pressure-flow-rate curve,the experimental investigation was carried out at rotor inlet and outside of rotor blade tip without casing in a semi-opened propeller fan using a hot-wire anemometer.A single I-type hot-wire probe was used,and the data obtained were processed by the use of phase-locked averaging,ensemble averaging and FFT analyzing.The flow fields at rotor inlet and outside of rotor blade tip were discussed mainly using the results from distributions of velocity fluctuations and power spectrum density.It was found from these results that there are the two types of different periodical fluctuations and both of those frequencies were not the same of rotor rotating frequency(RRF; 15Hz).One was observed at relatively high flow-rate region at relatively downstream area in measurement and its frequency was approximately 7Hz(47%of RRF).The other was observed at relatively low flow-rate region at relatively upstream area in measurement and its frequency was approximately 10Hz(67%of RRF)".As the velocity fluctuations with the flow fields are rapidly increased by the former fluctuation,it is thought that its fluctuation is the trigger of blade stall.
低分子肝素对急性冠脉综合征患者内源性抗纤溶系统及血小板活化的影响

不稳定斑块破裂导致血小板聚集进而引发血栓形成是急性冠脉综合征 (ACS)发病的关键环节之-[1]。凝血酶 Ⅱa是血小板聚集的强诱导剂，对促进血栓形成有重要作用；凝血酶还可激活凝血酶活化的纤溶抑制物(TAFI)来下调纤溶系统的活性；另外，凝血酶还影响纤溶酶原激活物抑制剂-1 (PAI-1)的活性。[取自正文]
急性大面积肺栓塞静脉溶栓治疗成功1例

APE已成为我国常见心血管疾病，在美国也是公认的三大致死性心血管疾病之一。最新研究表明，全球每年确诊的肺栓塞(PE)和深静脉血栓形成(DVT)患者约数百万例。PE一旦发生，肺动脉管腔阻塞，血流减少或中断，可不同程度地改变血流动力学和呼吸功能，轻者无任何症状，重者可导致肺血管阻力突然增加，肺动脉压升高，心排血量下降；严重时因冠状动脉和脑动脉供血不足，可致晕厥甚至死亡。[取自正文]
再谈消防水池取水井的设置

对《高层民用建筑设计防火规范》(GB 50045—95,2005年版)和《建筑设计防火规范》(GB 50016—2006)相关条文中关于消防水池取水井(取水口)容积的计算进行了分析。并针对一些室外消防用水量大于15L/s的工程,在消防时只有一台消防车在取水井(取水口)进行取水是否能满足现行规范中所规定的室外消防用水量,提出了自己的观点。
西江引水工程水源置换管网运行调度措施

西江水引至广州后,整体供水布局发生了变化,为使西江水平稳置换原管网水,制定切实可行的管网调度方案及并网阀门调整方案,采用可靠的管网置换技术,使西江水置换期间管网水质不出现问题,保证市民的用水安全。总结了管网水置换前的准备工作,以中山一立交区域为例,介绍了操作步骤和要点。
某清水池变形缝堵漏密封技术介绍

介绍了江阴周庄增压泵站清水池变形缝进行堵漏密封的工程案例。结合现场实际情况的调研,与传统密封方法进行对比,最终采用飞玛度变形缝压缩密封系统和齿轮防水带密封系统有机结合的方案,取得了理想的密封效果。
广州亚运城太阳能生活热水系统的思考

对广州亚运城太阳能热水系统的设计和运行进行总结,提出应注意的问题,如:太阳能集中供应系统应采用最高日和平均日两个热水定额设计,集热系统的用水标准可按最高日定额成比例折算;室外热水管道不宜同程布置,应就近回到机房;热泵作太阳能热水系统辅助热源应与空调供冷联用;集中热水供应的平面分区应考虑低入住率因素;开式循环回水应严格控制循环水量;集中热水供应系统应特别关注管网散热损失。
袍江工业区分质供水规划模式探索

通过介绍绍兴市袍江工业区分质供水规划实例,重点阐明已建成工业区分质供水规划,特别是其中的工业供水管网规划模式和方法,通过数据调查和分析,确定企业工业供水真实需求,在工业供水管网规划中反映了建成区供水规划需求的不均匀分布。实践表明,这一模式的采用有效提高了分质供水规划的经济性和科学性。
中新天津生态城雨水利用的可行性分析

通过介绍绿色建筑的评价体系,阐述了雨水综合利用中有关入渗、调蓄排放、回用等途径的系统特点、适用条件及主要计算方法。结合中新天津生态城项目,并通过对系统主要设施的计算,比较了各种雨水利用方案的优劣。
乳制品废水处理工艺选择与工程设计

介绍了乳制品废水的来源、分布及其水质特点,通过对几种常用工艺流程和工艺单元的分析比较,提出了工艺选择的一般原则和常用的关键工艺参数。根据一个具体工程实例,对乳制品废水处理的技术经济指标进行测算,并对工程设计中的一些共性问题做了归纳总结,提出了优化工程设计的一些建议。
提高收集系统效率重视排水管网建设

城镇排水管网建设严重滞后于经济社会的发展,滞后于污水处理厂的建设,已建排水收集系统的效率亟待提高。基础设施建设的规律“先地下、后地上”这一原则,越来越受到只注重表面政绩观的挑战。无论从城市内涝防治,还是污水有效收集及面源污染控制考虑,都应重视排水管网的建设,贯彻源头治理原则,开展扎实有效的工作,提高收集系统效率。[取自正文]
室外管道综合设计方法探讨

总结了当前管道综合设计中由市政规划部门牵头、由总图专业牵头和由给排水专业牵头组织等三种方式，分析了其存在的问题，探讨新的设计方法，旨在减轻工程设计人员劳动强度、提高工作效率。
昆山长江引水工程顶管沉管连贯施工技术

介绍了昆山长江引水工程顶管沉管连贯施工技术。施工内容包括:2×DN2 200钢管顶管穿越长江大堤、江内沉管施工，以及顶管段与沉管段的连接等。采用泥水平衡顶进、精确控制土体稳定性等优化施工方案，解决了顶距长、影响江堤安全、水上水下作业面小等施工难题。分项工程质量合格率达到了100%。
有上盖开发地铁车辆基地消防给水系统设计探讨

为贯彻国家“建设资源节约型、环境友好型社会”和“节约土地、集约发展”政策，国内很多在建地铁车辆基地进行了上部综合物业开发。针对有上盖开发地铁车辆基地的消防给水系统设计，从建筑分类的明确、消防给水系统形式的选择、自动灭火系统的设置以及特殊部位消火栓布置等问题进行简要分析，并提出一些具体建议，供同类工程设计参考。
电厂海水循环冷却水管道系统设计

深圳某电厂根据厂址的特殊条件，针对给排水管道系统中水锤防护问题以及管道敷设优化设计两方面，采用“准调压室”方法解决大管径、大流量的给水系统水锤防护问题，论述了在保证系统安全和经济前提下的管材选择与管道敷设，为以海水为冷却水的电厂管道系统设计提供借鉴。
宝钢罗泾区域全膜法纯水利备系统的运行与维护

宝钢罗泾区域的全膜法纯水站投产使用至今已近4年，对纯水系统的运行维护情况进行了分析总结并针对运行故障和清洗方面存在的问题提出了应对措施。
免疫毒性评价方法研究进展

免疫毒理学是毒理学或卫生毒理学的一门年轻的分支学科,与免疫学、分子生物学、微生物学、药理学、生理学等多种学科结合在一起,主要研究外源化学物和物理因素对机体免疫系统的有害作用及其机制。免疫毒性是某化学物作用于免疫系统后造成免疫系统功能或结构的损害,或是化学物作用于机体其他系统后引起免疫系统的损害,根据效应不同分为4个类型:免疫抑制、免疫刺激、超敏反应和自身免疫[1]。本文就免疫毒性常用评价方法及其进展进行综述。[取自正文]
两种皮瓣一期修复头皮鳞状细胞癌术后缺损疗效分析

目的 总结不同皮瓣一期修复头皮鳞状细胞癌术后缺损疗效。 方法 回顾分析 1997 年 1 月-2011 年 3 月收治的 44 例头皮鳞状细胞癌患者临床资料。男 32 例,女 12 例 ;年龄 36 ～ 65 岁,平均 45.2 岁。病程 1 个月～ 2年。病变部位 :额部 7 例,顶部 27 例,颞部 8 例,枕部 2 例。高分化鳞状细胞癌 38 例,低分化鳞状细胞癌 6 例。肿瘤切除后头皮缺损范围为 5 cm × 4 cm ～ 27 cm × 11 cm。33 例缺损 <10 cm × 8 cm 者采用大小为 6 cm × 5 cm ～ 10 cm ×8 cm 的邻近头皮瓣移位修复,11 例缺损 > 10 cm × 8 cm 者采用大小为 11 cm × 9 cm ～ 28 cm × 12 cm 吻合血管的游离股前外侧皮瓣修复。供区采用游离植皮修复。术后正规放、化疗。 结果 术后 2 例皮瓣发生远端坏死,经换药后成活 ;其余皮瓣及供区植皮均成活,切口Ⅰ期愈合。放疗后皮瓣存活良好。30 例患者获随访,随访时间 2 ～ 3 年,平均 2.5 年。皮瓣质地、颜色与周围正常皮肤相似,无局部臃肿。术后平均 1.2 年 5 例低分化鳞状细胞癌患者复发,其余患者肿瘤无复发,存活良好。 结论 根据缺损大小选择合适的皮瓣一期修复头皮鳞状细胞癌切除后缺损,均可获得较好疗效。
Kinetic study on the non-isothermal crystallization of Gd53Al24Co20Zr3 bulk metallic glass

Gd-based bulk metallic glass has drawn strong attention because of its large magnetic entropy changes.Thermal stability of metallic glass is a very important issue for its application.In the paper,crystallization behavior of Gd53Al24Co20Zr3 bulk metallic glass was investigated using non-isothermal differential scanning calorimetric(DSC)technique.Attention was given to the analytic details.The crystallized volume fractions as a function of temperature were derived from the DSC signals,where heat capacity change between amorphous phase and crystalline phase was considered.The local activation energies at different crystallized volume fraction were estimated using Doyle-Ozawa and Agrawal methods.The results suggested that the Doyle-Ozawa equation was appropriate to get local activation energy due to its simplicity and accuracy.The local activation energy depended on the crystallized volume fraction.Function reflecting crystallization mechanism was also deduced.The crystallization mechanism of the Gd-based bulk metallic glass was discussed.
Magnetic susceptibility of Al2RE compounds in crystal and liquid states

Magnetic susceptibility of Al_2RE(RE=Y,Ce,Sm,Gd,Dy,Ho,Yb)compounds was studied experimentally in wide temperature (T=290-2000 K)and field(B=0.3-1.3 T)intervals.The abnormal increase in susceptibility beginning above the melting point was fixed for all the compositions.The values for the effective magnetic moments per RE atoms in these compounds were found to be smaller than the values typical for free ions RE~(3+).The results were discussed in supposition of the directed bonds between aluminum and rare-earth atoms.
Synthesis and electrochemical properties of Ce-doped LiNi_1/3Mn_(1/3)Co_(1/3)O_2 cathode material for Li-ion batteries

The layered material of Ce-doped LiNi_1/3Mn_(1/3)Co_(1/3)O_2 withα-NaFeO_2 was synthesized by a co-precipitation method.X-ray diffraction(XRD)showed that Ce-doped LiNi_1/3Mn_(1/3)Co_(1/3)O_2 had the same layered structure as the undoped LiNi_1/3Mn_(1/3)Co_(1/3)O_2.The scanning electron microscopy(SEM)images exhibited that the particle size of Ce-doped LiNi_1/3Mn_(1/3)Co_(1/3)O_2 was smaller than that of the undoped LiNi_1/3Mn_(1/3)Co_(1/3)O_2.The Ce-doped LiNi_1/3Mn_(1/3)Co_(1/3)O_2 samples were investigated on the Li extraction/insertion performances through charge/discharge,cyclic voltammogram(CV),and electrochemical impedance spectra(EIS).The optimal doping content of Ce was x=0.02 in the LiNi_(1/3-x)Mn_(1/3)Co_(1/3)Ce_xO_2 samples to achieve high discharge capacity and good cyclic stability.The electrode reaction reversibility was enhanced,and the charge transfer resistance was decreased through Ce-doping.The improved electrochemical performances of the Ce-doped LiNi_1/3Mn_(1/3)Co_(1/3)O_2 cathode materials were attributed to the addition of Ce~(4+)ion by stabilizing the layer structure.
巨大精囊囊肿超声表现1例

精囊囊肿临床上很少见,根据来源可分为先天性和继发性2种。先天性精囊囊肿常合并泌尿、生殖系统畸形。因此,在超声检查中应重视生殖系统与泌尿系统联合畸形的发生,以免漏诊。后天性精囊囊肿多发生于成年人,常系生殖系感染、射精管结石等导致射精管梗阻引起,炎症引起射精管或精囊憩室口的狭窄造成精囊内液体潴留和内压升高而形成囊肿,本例就属此种。精囊囊肿超声图像表现为在膀胱后壁与前列腺底部之间、中线一侧的单腔或呈多房薄壁囊肿。[取自正文]
Effects of Vegetation Cover and Rainfall Intensity on Sediment-Bound Nutrient Loss,Size Composition and Volume Fractal Dimension of Sediment Particles

Vegetation and rainfall are two important factors affecting soil erosion and thus resulting in nutrient loss in the Chinese Loess Plateau.A field experiment was conducted to investigate the Effects of rainfall intensities(60,100 and 140 mm h~(-1))and vegetation(Caragana korshinskii)coverages(0%,30%and 80%)on soil loss,nutrient loss,and the composition and volume fractal dimension of eroded sediment particles under simulated rainfall conditions.The results showed that vegetation cover,rainfall intensity and their interaction all had significant Effects on sediment transport and the sedimentbound nutrient loss.Higher rainfall intensity and lower coverage led to higher sediment and nutrient losses.Positive linear relationships were observed between soil loss and nutrient loss.The treatments showed more significant Effects on the enrichment ratio(ER)of nitrogen(ERN)than organic matter(EROM)and phosphorus(ERP).Compared with the original surface soil,the eroded sediment contained more fine particles.Under the same coverage,the clay content significantly decreased with increasing rainfall intensity.The ER of sediment-bound nutrients was positively correlated with that of clay, suggesting that the clay fraction was preferentially eroded and soil nutrients were mainly adsorbed onto or contained within this fraction.There were increments in the fractal dimension of the sediment particles compared to that of the original surface soil.Moreover,the fractal dimension was positively correlated with clay,silt,and sediment-bound OM,N,and P contents,whereas it was negatively correlated with sand content.This study demonstrated that fractal dimension analysis can be used to characterize differences in particle-size distribution and nutrient loss associated with soil erosion.
Role of Organic Matter and Carbonates in Soil Aggregation Estimated Using Laser Diffractometry

Aggregation in many soils in semi-arid land is affected by their high carbonate contents.The presence of lithogenic and/or primary carbonates can also influence the role of soil organic matter(SOM)in aggregation.The role of carbonates and SOM in aggregation was evaluated by comparing the grain-size distribution in two carbonate-rich soils(15%and 30% carbonates)under conventional tillage after different disaggregating treatments.We also compared the Effect of no-tillage and conventional tillage on the role of these two aggregating agents in the soil with 30%of carbonates.Soil samples were treated as four different ways:shaking with water(control),adding hydrochloric acid(HCl)to remove carbonates,adding hydrogen peroxide(H_2O_2)to remove organic matter,and consecutive removal of carbonates and organic matter(HCl+ H_2O_2),and then analyzed by laser diffraction grain-sizing.The results showed that different contributions of carbonates and SOM to aggregate formation and stability depended not only on their natural proportion,but also on the soil type,as expressed by the major role of carbonates in aggregation in the 15%carbonate-rich soil,with a greater SOC-to-SIC(soil organic C to soil inorganic C)ratio than the 30%carbonate-rich soil.The increased organic matter stocks under no-tillage could moderate the role of carbonates in aggregation in a given soil,which meant that no-tillage could affect the organic and the inorganic C cycles in the soil.In conclusion,the relative role of carbonates and SOM in aggregation could alter the aggregates hierarchy in carbonate-rich soils.
青少年可待因依赖患者的心理行为干预与护理

目的探索符合青少年可待因依赖患者的行为干预模式,提高治疗效果,更好地预防复吸。方法将100例住院的青少年可待因依赖患者随机分为研究组和对照组各50例,研究组除了药物治疗外还采用心理替代治疗、健康教育及认知-行为干预,对照组则单用药物维持治疗。比较干预前、后两组患者进行的《滥用止咳药水信念》(BACMAS)、心理健康状况、回归社会功能和复吸率。结果研究组干预后的BACMAS和症状自评量表 (SCL-90)各因子评分改善明显优于对照组(P＜0.01);研究组复吸率37.9%,明显低于对照组的87.4%(P＜ 0.01)。结论心理行为干预可以更好地消除患者的病态心理和降低对止咳药的心理信念,减少复吸及他们的犯罪行为,使青少年更好地返回学校或回归社会。
Retention and Mobility of Copper and Lead in Soils as Influenced by Soil Horizon Properties

The mobility and bioavailability of heavy metals in soils is largely governed by sorption and desorption phenomena. Cu~(2+)and Pb~(2+)are among the most potentially toxic heavy metals and they are present,often concomitantly,in many polluting spills and in agrochemicals.The objective was to assess and compare the competitive sorption and desorption capacities and sorption hysteresis of Cu~(2+)and Pb~(2+),as well as their migration through the profiles of four natural soils:a Humic Umbrisol,an Umbric Cambisol,an Endoleptic Luvisol and a Humic Cambisol.In all horizons Pb~(2+)was invariably sorbed and retained to a greater extent than Cu~(2+).The sorption and retention of Cu~(2+)were most influenced by pH, Effective cation exchange capacity(CECe)and Mn oxide content.On the other hand,the fixation capacity of Pb~(2+)was most influenced by pH,CECe,and Mn oxide and organic matter contents.pH and CECe were the individual soil properties most markedly influencing Cu~(2+)and Pb~(2+)sorption and retention.In all the horizons Pb~(2+)exhibited greater hysteresis than Cu~(2+).In each soil the hysteresis in the A horizon was greater than that in the B horizon,except in the Bt horizon of the Endoleptic Luvisol,due to its high pH and vermiculite content.Based on migration indices,Pb~(2+)was less mobile than Cu~(2+)in the studied soils.
Correlation Between CO2 Effux and Net Nitrogen Mineralization and Its Response to External C or N Supply in an Alpine Meadow Soil

In nutrient-limited alpine meadows,nitrogen(N)mineralization is prior to soil microbial immobilization;therefore, increased mineral N supply would be most likely immobilized by soil microbes due to nutrient shortage in alpine soils.In addition,low temperature in alpine meadows might be one of the primary factors limiting soil organic matter decomposition and thus N mineralization.A laboratory incubation experiment was performed using an alpine meadow soil from the Tibetan Plateau.Two levels of NH4NO3(N)or glucose(C)were added,with a blank without addition of C or N as the control, before incubation at 5,15,or 25℃ for 28 d.CO2 Effux was measured during the 28-d incubation,and the mineral N was measured at the beginning and end of the incubation,in order to test two hypotheses:1)net N mineralization is negatively correlated with CO2 Effux for the control and 2)the external labile N or C supply will shift the negative correlation to positive.The results showed a negative correlation between CO2 Effux and net N immobilization in the control.External inorganic N supply did not change the negative correlation.The external labile C supply shifted the linear correlation from negative to positive under the low C addition level.However,under the high C level,no correlation was found.These suggested that the correlation of CO2 Effux to net N mineralization strongly depend on soil labile C and C:N ratio regardless of temperatures.Further research should focus on the Effects of the types and the amount of litter components on interactions of C and N during soil organic matter decomposition.
Distribution of Soil Organic Carbon Fractions Along the Altitudinal Gradient in Changbai Mountain,China

Understanding the responses of soil organic carbon(SOC)fractions to altitudinal gradient variation is important for understanding changes in the carbon balance of forest ecosystems.In our study the SOC and its fractions of readily oxidizable carbon(ROC),water-soluble carbon(WSC)and microbial biomass carbon(MBC)in the soil organic and mineral horizons were investigated for four typical forest types,including mixed coniferous broad-leaved forest(MCB), dark coniferous spruce-fir forest(DCSF),dark coniferous spruce forest(DCS),and Ermans birch forest(EB),along an altitudinal gradient in the Changbai Mountain Nature Reserve in Northeast China.The results showed that there was no obvious altitudinal pattern in the SOC.Similar variation trends of SOC with altitude were observed between the organic and mineral horizons.Significant differences in the contents of SOC,WSC,MBC and ROC were found among the four forest types and between horizons.The contents of ROC in the mineral horizon,WSC in the organic horizon and MBC in both horizons in the MCB and EB forests were significantly greater than those in either DCSF or DCS forest.The proportion of soil WSC to SOC was the lowest among the three main fractions.The contents of WSC,MBC and ROC were significantly correlated(P<0.05)with SOC content.It can be concluded that vegetation types and climate were crucial factors in regulating the distribution of soil organic carbon fractions in Changbai Mountain.
PRDXⅢ在人脑胶质瘤组织中的表达及意义

目的探讨PRDXⅢ在不同级别胶质瘤组织中的表达水平以及在胶质瘤细胞凋亡中的作用。方法通过免疫组织化学方法检测PRDXⅢ蛋白在胶质瘤和正常脑组织的表达水平,利用Tunel法检测细胞凋亡指数。分析不同级别胶质瘤及脑组织相互间PRDXⅢ表达水平的差异以及与细胞凋亡指数间的关系。结果PRDXⅢ蛋白在正常脑组织、低级别胶质瘤、高级别胶质瘤组织中表达阳性率分别为20.0%(2/10)、30.3%(10/33)和 81.3%(26/32),高级别胶质瘤PRDXⅢ蛋白表达阳性率明显高于正常脑组织和低级别胶质瘤。随病理级别增高,PRDXⅢ蛋白表达强度也明显增加(r=0.576,P=0.00)。正常脑组织、低级别胶质瘤、高级别胶质瘤组织的凋亡指数分别为(24.51±3.27)%、(17.68±2.27)%和(8.78±3.02)%,随着胶质瘤级别的增高,凋亡指数逐渐降低,差异有统计学意义(F=74.45,P=0.00)。在正常脑组织和胶质瘤中,PRDXⅢ蛋白表达阳性组的凋亡指数为 (10.29±4.87)%,PRDXⅢ蛋白表达阴性组为(19.07±4.64)%,PRDXⅢ蛋白表达阳性组的凋亡指数明显低于 PRDXⅢ阴性组(t=7.99,P=0.00)。结论PRDXⅢ在胶质瘤中高度表达,表达强度随着肿瘤级别的增高而增加,高级别级胶质瘤中PRDXⅢ表达的强度明显高于低级别胶质瘤和正常脑组织,说明PRDXⅢ可能与胶质瘤的生长和恶性表型有关。在PRDXⅢ表达阳性的胶质瘤中,细胞的凋亡指数低于PRDXⅢ表达阴性者。
亨廷顿病转基因动物模型研究进展

HD亨廷顿蛋白(htt)的发现使得建立与人类亨廷顿病(HD)有相似遗传基础的动物模型成为可能~([1])。随机插入人类htt基因(包含聚谷氨酰胺重复序列)部分片段而构建的转基因动物模型~([1]),能模拟人类HD发病时的病因和病理特征且能被用来研究HD的治疗策略,现综述目前HD转基因动物模型的研究进展。[取自正文]
Sulfamic acid: An efficient, cost-effective and green catalyst for crossed-aldol condensation of ketones with aromatic aldehydes under solvent-free

Aromatic aldehydes undergo crossed-aldol condensation with ketones in the presence of catalytic amount of sulfamic acid (SA) to afford the corresponding a, β-unsaturated aldol products under solvent-free conditions in good to high yields at 45-80 ℃.
中美新药研发管理系统协调性分析

从新药研发人才管理、投资管理、研发质量管理和知识产权保护四个角度，对比分析了中美两国政府新药研发管理系统协调性，为提高我国新药研发管理系统协调性、增强医药研发能力提供政策参考。建议我国加强医药科技人才队伍建设，建立统一的政府投资协调机构，加强审批中的沟通交流机制，加大知识产权保护的范围和执行力度。
Microwave-assisted synthesis of some novel fluorinated pyrazolo[3,4-d]pyrimidine derivatives containing 1,3,4-thiadiazole as potential antitumor agents

A facile microwave-assisted procedure for synthesis of novel fluorinated pyrazolo[3,4-d]pyrimidine derivatives containing 1,3,4-thiadiazole is described. This protocol presented such advantages as short reaction time, high yields, simple purification and environmentally benign procedures. Their antitumor activities were evaluated against HL-60 by an MTT assay. The preliminary results indicated that some title compounds exhibit more potent antitumor inhibitory activity than doxorubicin (DOX).
不同剂量的粒细胞集落刺激因子对兔股动脉粥样斑块的作用

目的:探讨不同剂量的粒细胞集落刺激因子(G- CSF)对兔股动脉粥样斑块的作用。方法:24只新西兰兔以高脂饮食和股动脉球囊扩张建立动脉粥样硬化模型,随机分为空白对照组(8只),小剂量G-CSF干预组(8只)和大剂量 G-CSF干预组(8只)。空白对照组不给药;小剂量G-CSF组隔天皮下注射G-CSF 0.8 mL(4 μg．kg-1．d-1),共7针;大剂量G-CSF组隔天皮下注射G-CSF 2.4 mL(12 μg．kg-1． d-1),共7针。造模前、给药结束后及给药结束3周后分别测定血常规。给药结束3周后,取股动脉粥样斑块进行HE染色和CD34免疫组化染色,测定斑块内泡沫细胞比例和新生血管计数。结果:各组在G-CSF干预前后的白细胞计数、中性粒细胞计数、血红蛋白量均无明显差别。大剂量G-CSF组在给药结束3周后的中性粒细胞比例明显低于基线值(P<0.01)。小剂量G-CSF组在给药结束后、大剂量G-CSF组在给药结束3周后的血小板计数均高于用药前水平(P< 0.05,P
河北省种子产业的SWOT分析

河北省作为农业大省，用种大省，其种业的发展肩负着农民增收，确保粮食安全和提高农业综合生产能力等重要任务。笔者利用SWOT方法对河北省种子产业的影响因素进行了分析，在此基础上，利用策略配对方法，得出了发展对策。
利用种子发芽试验检测抗草甘膦棉花新品系

通过室内发芽试验检验了3个棉花品种(系)对草甘膦除草剂的抗性。首先将41%的草甘膦设置了3个浓度梯度,即配置成40倍液、60倍液、80倍液,分别处理种子和出苗12 d的幼苗。结果表明,所选育的2个抗性材料在发芽率、发芽势和幼苗耐受性方面,均比非抗材料鲁棉研21有明显的优越性,同时也证明室内发芽试验是检测抗除草剂棉花抗性的一种快速有效的方法。
不同燕麦品种萌芽期抗旱性初步研究

对NY-1、NY-2、9818-1-19、花早2号、坝莜6号5个燕麦品种进行萌芽期抗旱性研究。结果表明,水分胁迫降低了品种的发芽势和发芽率,阻碍了胚芽和胚根的生长,也降低了种子中贮藏物质的利用效率。燕麦品种NY-2、坝莜6号、NY-1、9818-1-19、花早2号的萌发抗旱指数在0．04～0．37之间变动,NY-2的萌发抗旱指数最高,说明具有较强的抗旱性,坝莜6号的抗旱性中等,NY-1较弱,9818-1-19和花早2号不抗旱。
内蒙古3种野生葱属植物种子吸水与萌发特性研究

以内蒙古草原上常见的蒙古韭(A．mongolicum)、碱韭(A．polyrhizum)和细叶韭(A．tenuissimum)3种葱属植物为材料,对其种子吸水特性及在不同温度和光照条件下的萌发特性进行了研究。结果表明,蒙古韭种子在30 h内吸水饱和,其吸水量为种子重量的77%;碱韭种子在34 h内吸水饱和,其吸水量为种子重量的73%;细叶韭种子在26 h内吸水饱和,其吸水量为种子重量的60%。3种野生葱属植物种子自然休眠期约7个月。蒙古韭和细叶韭的种子属于种孔抑制和胚后熟的综合型休眠;碱韭种子属于种孔抑制的强迫性休眠。3种野生葱属植物种子适宜萌发温度为15℃恒温或15～25℃变温。黑暗对细叶韭种子萌发无明显促进作用。而蒙古韭和碱韭种子萌发具有一定的嫌光性。在适宜萌发条件下,3种野生葱属植物种子萌发率均能达到90%以上。
中国樱桃花粉活力检测方法的比较

利用TTC法、I-IK法及离体萌发法对红枫湖(Prunus pseudocerasu L．‘Hongfenghu’)、百花湖(Prunus pseudocerasu L．‘Baihuahu’)、赫章(Prunus pseudocerasu L．‘Hezhang’)及黑珍珠樱桃(Prunus pseudocerasu L．‘Blackpearl’)的花粉活力进行了检测,并对蔗糖和硼酸浓度的影响进行了研究。结果表明:I-IK法及离体萌发法均适合红枫湖樱桃花粉活力检测,而其余3种樱桃以离体萌发法较为准确;4种樱桃花粉离体萌发所需的蔗糖浓度不一样,而0．5 g/L硼酸均可获得最高萌发率。
多花胡枝子野生种质材料芽期耐盐性评价

为加强耐盐性种质资源的研究,选20种不同生境下野生多花胡枝子材料,根据各材料在7个浓度梯度盐胁迫下的发芽势、发芽率、胚根胚芽比等变化情况,利用模糊数学中隶属函数法综合分析研究其耐盐性。结果表明,随着盐浓度的增加,各个材料的发芽率、发芽势、发芽指数和活力指数都呈下降趋势,胚根胚芽比在低盐浓度下降低,在高盐浓度下升高,表明低盐浓度对野生多花胡枝子种子萌发有一定促进作用,而高盐浓度则严重抑制种子的萌发。相同盐浓度下,不同材料间也呈显著差异性(p＜0．05)。平定冠山的L 6材料耐盐性较强,可作为多花胡枝子耐盐育种的材料,而黑山寨的L 16较差。
HPLC法同时测定三多丸中葛根素和芒柄花素含量

目的:建立同时测定三多丸中葛根素和芒柄花素含量的方法。方法:运用HPLC法进行测定研究,采用 Agilent Hypersil C18(250 mm×4.6 mm,5μm)柱,以乙腈-水为流动相,梯度洗脱,检测波长为250 nm,流速1.0 mL/ min。结果:HPLC法分析结果显示,葛根素和芒柄花素的色谱峰形好,分离度好,杂质无干扰,葛根素在0.288～2.88μg内呈现良好的线性关系,平均加样回收率为98.77%(RSD=1.2%),r=0.9999;芒柄花素在0.013～0.260 μg内呈现良好的线性关系,平均加样回收率为97.68%(RSD=1.9%),r=0.9998。结论:该方法分离度高、专属性强、重现性好,可有效用于三多丸中葛根素和芒柄花素的含量测定。
椎间孔打开切除哑铃形神经鞘瘤

椎管哑铃形神经鞘瘤切除有一定困难,手术涉及如何全切肿瘤、周围重要结构的保护、脊柱的稳定性和载瘤神经的处理等问题。我们自2006年6月至2010年5月间采用后正中人路打开椎间孔,显微镜直视下一期全切10例哑铃形神经鞘瘤,效果良好,现报道如下。[取自正文]
Study on the Characteristics of the Gas Switch Electrode Erosion

Gas spark switch is one of the key parts in pulsed power technology.Electrode erosion has great influence on the switch performance and lifetime.In this paper,a field distortion gas switch is selected for the experiment and a great deal of discharging experiments have been conducted in different test conditions.The forming process of etch pit as well as its influencing factors is discussed briefly and surface roughness coefficient(SRC)of the electrode is put forward to evaluate the state of electrode erosion.Experimental results show that current peak plays an important role in electrode erosion when waveforms of discharge current are the same,and electric charge and oscillation frequency of discharge current also have great effect on the electrode erosion when waveforms of discharge current are different. With the increase of discharge times,SRC decreases slowly at first and then decreases quickly after three thousand of discharge times.