mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Impact of time lags on diurnal estimates of canopy transpiration and canopy conductance from sap-flow measurements of Populus cathayana in the Qinghai–Tibetan Plateau

Recently, canopy transpiration (E_c) has been often estimated by xylemsap-flow measurements. However, there is a significant time lag between sap flow measured at the base of the stem and canopy transpiration due to the capacitive exchange between the transpiration stream and stem water storage. Significant errors will be introduced in canopy conductance (g_c) and canopy transpiration estimation if the time lag is neglected. In this study, a cross-correlation analysis was used to quantify the time lag, and the sap flowbased transpiration was measured to parameterize Jarvistype models of gc and thus to simulate E_c of Populus cathayana using the Penman–Monteith equation. The results indicate that solar radiation (R_s) and vapor pressure deficit (VPD) are not fully coincident with sap flow and have an obvious lag effect; the sap flow lags behind R_s and precedes VPD, and there is a 1-h time shift between E_c and sap flow in the 30-min interval data set. A parameterized Jarvis-type g_c model is suitable to predict P. cathayana transpiration and explains more than 80% of the variation observed in gc, and the relative error was less than 25%, which shows a preferable simulation effect. The root mean square error (RMSEs) between the predicted and measured Ec were 1.91 × 10~(-3) (with the time lag) and 3.12 × 10~(-3) cm h~(-1) (without the time lag). More importantly, E_c simulation precision that incorporates time lag is improved by 6% compared to the results without the time lag, with the mean relative error (MRE) of only 8.32% and the mean absolute error (MAE) of 1.48 × 10~(-3) cm h~(-1).
miR-21、miR-27a、miR-27b的表达水平对多囊卵巢综合征患者肥胖及代谢紊乱的影响

目的探讨多囊卵巢综合征(PCOS)患者外周血淋巴细胞miR-21、miR-27a、miR-27b的表达水平与肥胖及相关代谢紊乱的关系。方法收集PCOS患者60例(非肥胖组22例,肥胖组38例) 。电化学发光法检测其血清促卵泡素(bFSH) 、促黄体生成素(bLH) 、雌二醇(bE2) 、孕激素(bP) 、睾酮(bT) 、空腹胰岛素(FINS)水平,葡萄糖氧化酶法测定葡萄糖(Glu),实时荧光定量PCR(qPCR)法检测淋巴细胞miR-21、miR-27a、miR-27b的表达水平。肥胖组控制体重后复测上述指标。结果肥胖组bT、Glu、FINS、HOMA-IR水平均明显高于非肥胖组(P均< 0.05);肥胖组控制体重后BMI、bLH、bT、Glu、FINS、HOMA-IR水平较控制前均明显降低(P均< 0.05) 。肥胖组miR-21、miR-27a、miR-27b的表达水均明显高于非肥胖组(P均< 0.05),且控制体重后较控制前亦明显降低(P均< 0.05) 。miR-21的表达量与bT呈正相关(r = 0.342,P = 0.008),miR-27a、miR-27b的表达量与FINS呈正相关(r = 0.413,P = 0.001; r = 0.397,P = 0.002) 。结论miR-21、miR-27a和miR-27b可能参与PCOS患者肥胖及相关代谢紊乱的进程。
外泌体在肿瘤中的研究进展

外泌体(exosomes)是一种所有细胞都释放的胞外囊泡,其直径为30 ~ 150 nm。外泌体包含了DNA、RNA和蛋白质等内容物。外泌体可以调节细胞间通讯,活化它们所参与或相互作用的细胞内信号通路。外泌体可在肿瘤微环境中检测到,越来越多的证据表明外泌体在促进肿瘤生长中起到重要作用,其参与血管生成、免疫应答和肿瘤转移等活动。循环中的外泌体可能会成为液体活检且无创的生物学标志物应用到肿瘤患者的早期检测、诊断和治疗中。
Evaluation of alternative conceptual models for groundwater modelling

This study evaluates the alternative conceptual models for groundwater modelling. A true model was created with a synthetic alluvial fan-plain hydrogeological framework. Various alternative conceptual models were evaluated for groundwater flow simulations. The first alternative model is a single aquifer layer model; the second alternative model is a 3-layer aquifer model; and the third model is a 5-layer model consisting of 3 aquifers separated by 2 aquitards. All models could fit very well to the observations with optimized values of hydraulic conductivities. However, the single aquifer layer model can only compute water balance components with good accuracy. The 3-layer aquifer model can be used for water balance computation and groundwater head simulation with small errors. The 5-layer model is capable of simulating water budget, groundwater head distribution and travel times with high accuracy. Multimodel analysis found only the 3rd alternative model superior.
Feeder and post Deccan Trap dyke activities in the northern slope of the Satpura Mountain: Evidence from new ~(40)Ar-~(39)Ar ages

We present new ~(40)Ar-~(39)Ar plagioclase crystallization ages from the dykes exposed at the northern slope of the Satpura Mountain range near Betul-Jabalpur-Pachmarhi area,~800 km NE of the Western Ghats escarpment. Among the two plateau ages, the first age of 66.56±0.42 Ma from a dyke near Mohpani village represents its crystallization age which is either slightly older or contemporaneous with the nearby Mandla lava flows (63-65 Ma). We suggest that the Mohpani dyke might be one of the feeders for the surrounding lava flows as these lavas are significantly younger than the majority of the main Deccan lavas of the Western Ghats (66.38-65.54 Ma). The second age of 56.95±1.08 Ma comes from a younger dyke near Olini village which cuts across the lava flows of the area. The age correlates well with the Mandla lavas which are chemically similar to the uppermost Poladpur, Ambenali and Mahabaleshwar Formation lavas of SW Deccan. Our study shows that the dyke activities occurred in two phases, with the second one representing the terminal stage.
A comparative analysis among computational intelligence techniques for dissolved oxygen prediction in Delaware River

Most of the water quality models previously developed and used in dissolved oxygen (DO) prediction are complex. Moreover, reliable data available to develop/calibrate new DO models is scarce. Therefore, there is a need to study and develop models that can handle easily measurable parameters of a particular site, even with short length. In recent decades, computational intelligence techniques, as effective approaches for predicting complicated and significant indicator of the state of aquatic ecosystems such as DO, have created a great change in predictions. In this study, three different Al methods comprising: (1) two types of artificial neural networks (ANN) namely multi linear perceptron (MLP) and radial based function (RBF); (2) an advancement of genetic programming namely linear genetic programming (LGP); and (3) a support vector machine (SVM) technique were used for DO prediction in Delaware River located at Trenton, USA. For evaluating the performance of the proposed models, root mean square error (RMSE), Nash-Sutcliffe efficiency coefficient (NS), mean absolute relative error (MARE) and, correlation coefficient statistics (R) were used to choose the best predictive model. The comparison of estimation accuracies of various intelligence models illustrated that the SVM was able to develop the most accurate model in DO estimation in comparison to other models. Also, it was found that the LGP model performs better than the both ANNs models. For example, the determination coefficient was 0.99 for the best SVM model, while it was 0.96,0.91 and 0.81 for the best LGP, MLP and RBF models, respectively. In general, the results indicated that an SVM model could be employed satisfactorily in DO estimation.
Triassic magmatism in the eastern part of the South China Block:Geochronological and petrogenetic constraints from Indosinian granites

The granitic dykes in the Badu Group, Zhejiang Province, South China provide important insights on tectonic setting and crustal evolution of the South China Block (SCB) and the Indochina Block during Triassic. Here we report LA-ICP-MS U-Pb data of granitic rocks from the Hucun and Kengkou which show early Triassic ages of 242±2 and 232±3 Ma, respectively, representing their timing of emplacement. The dyke rocks are enriched in K, Al, LREE, Rb, Th, U, and Pb, and are depleted in Nb, Ta, Sr, and Ti. The rocks are characterized by highly fractionated REE patterns with (La/Yb)N ratios of 28.46-38.07 with strong negative Eu anomalies (Eu/Eu~* = 0.65-0.73). In situ Hf isotopic analyses of zircons from the Hucun granite yielded _(εHf)(t) values of-13.9 to-6.4 and two-stage depleted mantle Hf model ages of 1.68-2.15 Ga, which indicate that the magma was formed by partial melting of the Paleoproterozoic metasedimentary protoliths in the Cathaysia Block. The zircons from the Kengkou granite have _(εHf)(t) values ranging from-40.7 to 31.5 and yield two-stage depleted mantle Hf model ages of 0.99-2.49 Ga, indicating magma origin from a mixed source. The Hucun and Kengkou dykes, together with the Triassic A-type granites in SE China were probably generated during magmatism associated with crust-mantle decoupling along the convergent plate boundary between SCB and the Indochina Block.
CMV promoter and the mouse albumin promoter and enhancer triggered the elevation of hepatitis B virus envelope polypeptides

Hepatitis B virus (HBV) envelope polypeptides including large, middle, and major envelope polypeptides are involved in the assembly of virion, and mediate infection of human hepatocytes [1-5]. These peptides were reported to play important roles in regulating the amplification of replication intermediate (covalent closed circular DNA) [6]. However, the mechanism of HBV infection in human is not fully understood. Therefore, the in vitro expression of HBV envelope polypeptides may be helpful to address this issue.
Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer

High mobility group proteins (HMGs) are the second most abundant chromatin proteins and exert global genomic functions in the establishment of active or inactive chromatin domains.Through interaction with nucleosomes,transcription factors,nucleosome-remodeling machines and histones,the HMGs family proteins contribute to the fine tuning of transcription in response to rapid environmental changes.Mammalian high mobility group Bs (HMGBs) are characterized by two tandem HMG box domains followed by a long acidic tail.Recent studies demonstrated that high expression of HMGBs has been found in many cancers,such as prostate,kidney,ovarian,and gastric cancers.However,their roles in pancreatic cancer have seldom been reported.In this study,we assessed the diagnostic and prognostic values of HMGBs proteins,including HMGB1,HMGB2,and HMGB3,in pancreatic cancer from the Cancer Genome Atlas (TCGA) dataset.Our results demonstrated that HMGB2 predicted poor prognosis in pancreatic cancer.In vitro studies demonstrated that silencing HMGB2 inhibited cell proliferation and viability.Mechanistically,our results demonstrated that silencing HMGB2 decreased hypoxia inducible factor 1α (HIF1α) protein level and inhibited HIF1α-mediated glycolysis process.Further analysis indicated that HIF1α-targeted glycolytic genes,including GLUT1,HK2,and LDHA,are all prognostic factors and positively correlated with HMGB2 expression.Taken together,we discovered new prognostic and predictive markers for pancreatic cancer,and shed light on the novel function of HMGB2 in glycolytic control in cancer.
The effects and regulatory mechanism of RIP3 on RGC-5 necroptosis following elevated hydrostatic pressure

Necroptosis is a type of regulated cell death that has been implicated in various diseases.Receptor-interacting protein 3 (RIP3),a member of the RIP family,is an important mediator of the necroptotic pathway.Cleavage of RIP3 at Asp328 by caspase-8 abolishes the kinase activity of RIP3,which is critical for necroptosis.Moreover,RIP3 is significantly upregulated during the early stages of acute high intra-ocular pressure and oxygen glucose deprivation.In this study,the effects of RIP3 during elevated hydrostatic pressure (EHP) were investigated and the possible mechanism through which caspase-8 regulated RIP3 cleavage was explored.Flow cytometry analysis revealed that the number of EHP-induced necrotic retinal ganglion cell 5 (RGC-5) cells was reduced after RIP3-knockdown.Furthermore,malondialdehyde (MDA) levels and glycogen phos-phorylase (PYGL) activity in normal RGC-5 cells were much higher than those in RIP3-knockdown cells after EHP.EHP-induced RGC-5 necrosis was significantly reduced after treatment with buty-lated hydroxyanisole (BHA),a reactive oxygen species (ROS) scavenger.MDA levels and PYGL activity were lower in normal RGC-5 cells than those in cells with caspase-8 inhibition after EHP.Western blot analysis demonstrated that the RIP3 cleavage product was upregulated in cells with caspase-8 inhibition.Additionally,flow cytometry analysis revealed that the number of EHP-induced necrotic RGC-5 cells was increased after caspase-8 inhibition.Our results suggested that RGC-5 necroptosis following EHP was mediated by RIP3 through induction of PYGL activity and subsequent ROS accumulation.Thus,caspase-8 may participate in the regulation of RGC-5 necroptosis via RIP3 cleavage.
Molecular characterization of GhPLDα1 and its relationship with secondary cell wall thickening in cotton fibers

Phospholipase D (PLD) hydrolyzes phospholipids to generate a free polar head group (e.g., choline) and a second messenger phosphatidic acid and plays diverse roles in plant growth and development, including seed germination, leaf senescence, root hair growth, and hypocotyl elongation. However, the function of PLD in cotton remains largely unexplored. Here, the comprehensive molecular characterization of GhPLDα1 was explored with its role in upland cotton (Gossypium hirsutum) fiber development. The GhPLDα1 gene was cloned successfully, and a sequence alignment showed that GhPLDα1 contains one C2 domain and two HKD (HxKxxxxD) domains. Quantitative reverse transcriptase-polymerase chain reaction measured the expression of GhPLDα1 in various cotton tissues with the highest level in fibers at 20 days post anthesis (d.p.a.). Fluorescent microscopy and immunoblotting in tobacco epidermis showed the GhPLDα1 distribution in both cell membranes and the cytoplasm. An activity assay indicated changes in PLDα enzyme activity in developing fiber cells with a peak level at 20 d.p.a., coinciding with the onset of cellulose accumulation and the increased H_2O_2 content during fiber development. Furthermore, the inhibition of PLDα activity obviously decreased the cellulose and H_2O_2 contents of in vitro-cultured cotton fibers. These results provide important evidence explaining the relationship of GhPLDα1 with secondary cell wall thickening in cotton fibers in that GhPLDαl may correlate with the increased H_2O_2 content at the onset of secondary cell wall thickening, ultimately promoting cellulose biosynthesis.
民航招飞体检右位主动脉弓一例

目前随着多层螺旋CT、MRI、超声技术的快速发展,右位主动脉弓畸形都可以明确诊断。虽然右位主动脉弓在民航招飞体检标准中未有明确规定,但考虑其属于先天性心脏大血管畸形,予以不合格结论。
Experimental Studies on the Thermal Performance of a Parabolic Dish Solar Receiver with the Heat Transfer Fluids SiC + Water Nano Fluid and Water

An experimental investigation has been carried out with aa point focusing dish reflector of 12 square meters aperture area, exposed to the average direct normal irradiations of 810 W/m2. This work focuses on enhancinge the energy and exergy efficiencies of the cavity receiver by minimizing the temperature difference between the wall and heat transfer fluids. Two heat transfer fluids Water and SiC + water nano fluid have been prepared from 50 nm particle size and 1% of volume fraction, and experimented separately for the flow rates of 0.2 lpm to 0.6 lpm with an interval of 0.1 lpm. The enhanced thermal conductivity of nano fluid is 0.800115 W/mK with the k_(eff)/k_b ratio of 1.1759 determined by using the Koo and Kleinstreuer correlation. The maximum attained energy and exergy efficiencies are 29.14% and 24.82% for water, and 32.91% and 39.83% for SiC+water nano fluid. The nano fluid exhibits enhanced energy and exergy efficiency of 12.94% and 60.48% than that of water at the flow rate of 0.5 lpm. The result shows that the system with SiC+Water produces higher exergy efficiency as compared to energy efficiency; in the case of water alone, the energy efficiency is higher than exergy efficiency.
燃料电池驱动未来

面对日益凸显的能源和环境问题,世界各国早已经达成了谋求绿色可持续发展道路的共识。燃料电池作为新能源技术领域的热点,被普遍认为是一种高效清洁的新型发电方式,可灵活地为交通工具、家用电器、航空航天等提供动力。本文概述了燃料电池的发展历程、发电原理及现实应用等,重点介绍了目前燃料电池技术的发展与应用。
高效CO_2还原至CO催化剂:核/壳结构Cu/SnO_2纳米粒子

2016年我国的CO_2排放已达100亿吨/年左右,约占全球的30%,除了减少化石能源的使用和降低碳排放之外,如何有效地将过量排放的CO_2还原或转化,实现“碳中性”(carbon neutrality)的生态平衡是人类亟需解决的问题。由于CO_2化学性质稳定,需采用高温、高压或使用催化剂才能使其反应,因此从能源和经济角度来考虑,选择温和条件下利用电化学方法还原CO_2具有更大的发展潜力。
湖北宜昌地区寒武系水井沱组探获页岩气

中扬子中部黄陵隆起东南缘宜昌斜坡带在太古宙结晶基底之上,发育有元古宙至第四纪各时代地层,保存有埃迪卡拉系陡山沱组、寒武系水井沱组,奥陶系五峰组一志留系龙马溪组等多套黑色富有机质泥岩。区域构造稳定,地层产状平缓,页岩气地质条件优越,但页岩气的勘探一直未获突破。本文的目的旨在查明宜昌斜坡带寒武系水井沱组页岩的分布和含气性,确定页岩气储层特点,为区域页岩气的勘探开发提供基础资料。
生殖道沙眼衣原体感染的挑战与应对

2016年6月,在《柳叶刀-传染病》(The Lancet Infectious Diseases)杂志上发表的一篇有关生殖道沙眼衣原体感染危害的文章,将长久以来学术界对衣原体危害的讨论再次升温。如何有效地预防、控制沙眼衣原体感染,降低其感染的危害及疾病负担再次成为了热门话题。现从生殖道沙眼衣原体感染的预防和控制中面临的挑战及如何应对进行概述。
Intensive Radiosonde Measurements of Summertime Convection over the Inner Mongolia Grassland in 2014: Difference between Shallow Cumulus and Other Conditions

Using radiosonde measurements from 26 July to 30 July 2014 at Baiqi over the Inner Mongolia grassland of China, the vertical structure of shallow cumulus (SCu) clouds and associated environmental conditions were investigated. The cloud base height and the cloud top height of SCu was 3.4 km and 5 km, respectively. The temperature of the SCu layer was less than 0℃. The horizontal advection of specific humidity was smaller than the vertical transport in the atmosphere below 5 km. Above 5 km, the thermodynamic structure of the atmosphere remained stable. At the interface of the cloud layer and free air atmosphere, there was obvious wind shear and a temperature inversion (~2.9℃). Comparisons of environmental parameters associated with cumulus congestus, rain and clear days, showed that the formation of SCu was characterized by a higher Bowen ratio (high sensible heat flux and low latent heat flux), which indicated intensive turbulence in the boundary layer. The formation of SCu was associated with the boundary layer height exceeding the lifting condensation level. The maintenance of SCu was likely associated with the lower convective available potential energy,weak wind shear, and weak subsidence of the synoptic system, which did not favor the dramatic vertical development of SCu and thereby the transformation of SCu to cumulus congestus.
Statistical Characteristics of Raindrop Size Distribution in the Tibetan Plateau and Southern China

The characteristics of raindrop size distribution (DSD) over the Tibetan Plateau and southern China are studied in this paper, using the DSD data from April to August 2014 collected by HSC-PS32 disdrometers in Nagqu and Yangjiang, comprising a total of 9430 and 6366 1-min raindrop spectra, respectively. The raindrop spectra, characteristics of parameter variations with rainfall rate, and the relationships between reflectivity factor (Z) and rainfall rate (R) are analyzed, as well as their DSD changes with precipitation type and rainfall rate. The results show that the average raindrop spectra appear to be one-peak curves, the number concentration for larger drops increase significantly with rainfall rate, and its value over southern China is much higher, especially in convective rain. Standardized Gamma distributions better describe DSD for larger drops, especially for convective rain in southern China. All three Gamma parameters for stratiform precipitation over the Tibetan Plateau are much higher, while its shape parameter (μ) and mass-weighted mean diameter (D_m), for convective precipitation, are less. In terms of parameter variation with rainfall rate, the normalized intercept parameter (N_W) over the Tibetan Plateau for stratiform rain increases with rainfall rate, which is opposite to the situation in convective rain. The μ over the Tibetan Plateau for stratiform and convective precipitation types decreases with an increase in rainfall rate, which is opposite to the case for D_m> variation. In Z-R relationships, like "Z = AR~b", the coefficient A over the Tibetan Plateau is smaller, while its b is higher, when the rain type transfers from stratiform to convective ones. Furthermore, with an increase in rainfall rate, parameters A and b over southern China increase gradually, while A over the Tibetan Plateau decreases substantially, which differs from the findings of previous studies. In terms of geographic location and climate over the Tibetan Plateau and southern China, the precipitation in the pre-flood seasons is dominated by strong convective rain, while weak convective rain occurs frequently in northern Tibet with lower humidity and higher altitude.
房间隔缺损封堵器治疗肾切除术后肾动静脉瘘一例

对该患者的治疗我们有以下体会:(1) ASD封堵器的大盘径超过目标动脉4 mm就不会导致移位;(2)封堵器尽可能释放在肾动脉远端,为近心端填塞弹簧圈预留空间;(3)术后适度抗凝;(4)单纯封堵肾动脉侧瘘口也能取得良好结果。
21例肝脏良性占位性病变误诊分析

肝脏良性占位性病变类型繁多,除肝血管瘤、肝囊肿、肝脓肿外,其他类型肝脏良性占位性病变发病率较低,大多缺乏特异性症状、体征及影像学表现,术前诊断困难。我们回顾性分析21例肝脏良性占位性病变的患者诊治资料,提高对肝脏良性占位性病变的诊治效果。
结直肠癌分子靶向治疗的研究进展

分子靶向药物与传统细胞毒性药物的联合应用改善了晚期CRC患者的预后,但作用有限。尽管目前已有众多新的靶向药物正处于临床试验阶段,其中不少结果都令人失望。随着新一代测序技术的应用、大数据分析技术的发展,肿瘤治疗新型药物的开发将朝着个体化方向发展。肿瘤微环境、免疫应答及宿主药物反应在靶向治疗耐药机制中的作用需要进一步阐明,以获得更有效的治疗策略。
High-efficiency LED COB device combined diced V-shaped pattern and remote phosphor

To further improve the luminous efficiency of LED lightings, this Letter proposes a chip-on-board(COB) device by combining diced staggered V-shaped patterns and remote phosphors. The results show that the V-shaped patterned COB(V-COB) with vertex angles from 120o to 150o can achieve a~17% output power increase(OPI) compared to the conventional COB. V-COB remote phosphor devices(RPDs) are then manufactured and tested. The luminous efficiency of the proposed RPD represents an 11.6% increase at the correlated color temperature of~3000 K. Such an improvement can be attributed to both the decreases of total internal reflections and phosphor backscatterings.
Mixed Breather-Type and Pure Soliton Solution of DNLS Equation

A newly revised inverse scattering transform (IST) is used to solve the derivative nonlinear Schrodinger $\left({{\rm{DNL}}{{\rm{S}}^ + }} \right)$ equation with non-vanishing boundary condition (NVBC) and normal group-velocity dispersion, and a mixed type of soliton solution is found, which is composed of both pure and breather-type solitons. The mixed-soliton solution can degenerate into breathers and pure solitons when taking the limit of some special parameters, proving the validity of the mixed-type solution.
Novel Phosphorus Containing Flame Retarded RTV Silicone Rubbers

A reactive flame retardant cross-linker (SPTES) was successfully synthesized with dichloropentate and 3-triethoxysilylpropylamine (APTES) in this research. Then it was further applied into the room temperature vulcanized (RTV) silicone rubber to prepare novel flame retarded RTV silicone rubbers containing phosphorus. The structure, thermal degradation stability, mechanical properties and flammability properties of the novel RTV silicone rubbers were tested and characterized. The results showed that the mechanical and flammability properties of the RTV silicone rubber simultaneously got better with the SPTES content increased. Compared with the sample prepared by APTES, the tensile strength of novel RTV silicone rubbers increased from 0.12 MPa to 0.38 MPa and the limit oxygen index increased from 19.8 to 23.5.
Revitalization of Urban Brownfield: Case Study on the Planning of the Central Park of Nanhu Eco-City in Tangshan

The redevelopment and regeneration of coal mining subsidence area has always been a hot topic in the field of social and scientific research. Relying on remote sensing and the geographic information system (GIS) platform and considering the opinions of experts from various disciplines, this paper intends to take the landscape planning and design of the coal mining subsidence area in Nanhu of Tangshan as an example to discuss the planning design strategies and substantial implementing approaches to transform abandoned urban land into a national urban wetland park, which specifically includes: ① anticipation of geological subsidence disaster and construction of ecological security pattern; ② coal ash management; ③ garbage mountain transformation; ④ application of eco-technologies for solving ground subsidence, etc., so as to provide technical methods and research ideas for the utilization directions, ecological protection, and construction of urban brownfield in similar areas all over the world.