mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
古城地区碳酸盐岩沉积特征及其主控因素

通过岩心精细描述、薄片鉴定、测井和地震特征及古地貌等分析,认为塔里木盆地古城地区寒武一中晚奥陶世主要处在台地一台地边缘一台缘斜坡相带,发育台内滩、台地边缘滩(礁滩复合体)、滩间海、台缘斜坡等微相类型。中下奥陶统鹰山组三段台缘滩和中上寒武统发育的纵向叠置的台缘丘滩体是有利的沉积相带,也是下一步勘探的重点。古地貌特征及其演化控制着沉积相带及礁滩体的分布,台缘坡折带决定了台缘带的分布位置,古地貌高隆区控制着台缘滩的发育。塔东地区沉积相演化主要受海平面升降控制,表现为台地类型的变化和台地边缘相带的迁移。探讨古城地区碳酸盐岩台地沉积微相特征及主控因素,圈定有利沉积相带,对于该区下步油气勘探具有重要的指导意义。
阿尔凹陷下白垩统不整合与油气成藏

为了搞清阿尔凹陷下白垩统腾一段不整合与油气成藏关系,从分析不整合形成背景、不整合类型和空间结构入手,利用自然电位、补偿密度、井径等测井曲线的电性特征,对不整合纵向结构进行划分,研究不整合对油气成藏影响。研究认为:腾一段成熟生油层内不整合在形成过程中,风化淋滤改善了储层物性,为油气聚集提供了空间,形成的裂缝系统和溶蚀孔洞系统为油气运移提供了通道,使其成为有利的“聚油面”。上述认识对二连盆地其他凹陷油气成藏研究具有一定的借鉴意义。
吉木萨尔凹陷致密油有利区预测及潜力分析

吉木萨尔凹陷二叠系芦草沟组发育一套云质岩储集层,是致密油勘探的重点区域和层位。该区域致密油以源储一体及源储互层为特征,形成了良好的源储配置关系。根据钻井、测井、地震及样品实测数据,结合前人研究成果,在详细剖析吉木萨尔凹陷二叠系芦草沟组致密油石油地质特征的基础上,考虑致密油储层的孔隙度、储层厚度以及烃源岩有机碳含量、成熟度等因素,确定了致密油资源评价参数分类标准,将芦草沟组上、下“甜点体”各划分出I、Ⅱ、 Ⅲ类有利区。使用小面元容积法对吉木萨尔凹陷致密油有利区进行资源预测,芦草沟组上、下“甜点体”石油地质资源量分别为4.72×10~8、7.49×10~8t。研究表明,吉木萨尔凹陷二叠系芦草沟组致密油具有较大的勘探潜力。
东营凹陷林樊家地区稠油特征及成因机制

济阳坳陷东营凹陷林樊家地区馆陶组稠油特征及其成因机制仍不甚清楚,制约了稠油的勘探与开发。为此,对原油物性、族组成、色谱、质谱等有机地球化学资料进行分析,并结合洼陷内油源对比分析。研究认为,林樊家地区馆陶组原油经过微生物降解作用发生稠变,形成以高密度、高黏度和高含硫量为特征的稠油。稠变程度主要受控于地层水的性质以及与油层接触的地层水的规模,具有“中间低、周边高”的特征。研究成果对该区深入勘探开发具有一定的指导意义,也可为浅层稠油降解气的研究提供理论基础。
高通道压裂非均匀铺砂技术研究进展

高通道压裂技术已成为开发非常规油气资源的重要增产措施。非均匀铺砂技术是高导流裂缝通道形成的关键。在系统调研非均匀铺砂技术相关文献的基础上,从工艺技术、压裂液改进技术及支撑剂表面改性技术3个方面,阐述了支撑剂“团簇”的形成、保持与强化技术的最新研究进展。指出非固化树脂聚砂技术和降低电位聚砂技术是实现非均匀铺砂的关键,是未来支撑剂改性的方向,并从支撑剂改性机理、技术优点及现场应用3个方面综述了上述2种支撑剂改性技术。分析了非均匀铺砂技术及支撑剂表面改性技术所存在的问题及发展趋势,以期为国内高通道压裂技术的推广应用提供一种新的思路。
库车坳陷大北地区古近纪沉积特征及盐湖演化

依据岩性组合及测井曲线变化,对大北地区古近系膏盐岩进行分段研究,结合元素地球化学分析,研究其沉积环境,建立古盐湖演化模式。研究认为:该区古近系膏盐岩可分为3段,即下部膏泥岩段、中部膏盐岩段和上部泥岩段。古气候主要为干热气候,湖泊可分为微咸水湖、半咸水湖、咸水湖和盐湖,为常年性较深水湖泊下的缺氧还原环境。研究区盐湖演化存在多期补给和咸化事件,初始阶段(膏泥岩段)对应于3次海侵事件及3次强烈蒸发阶段;中一高级阶段(膏盐岩段)在强烈蒸发时期发生2次盐湖淡化事件;消亡阶段(泥岩段)盐湖快速淡化。该研究为研究区盐下油气勘探提供了地质基础,对古气候、古环境指示具有重要意义。
渤中凹陷西北缘边界断层面特征与油气成藏

为解释渤中凹陷西北缘陡坡带边界油气分布的差异性并预测油气藏的分布,利用三维地震、钻井、测井和分析化验等资料,探讨了该地区断层面形态对油气运移和聚集的影响。结果表明:剖面上,渤中凹陷西北缘烃源岩之上的边界断层面形态主要以铲式下凹型和座椅式下凸型为主,且均表现为上陡下缓的特征;平面上,边界断层面主要发育汇聚型、发散型、均匀型和复合型等4种类型。汇聚型和复合型的位置为油气优势运移方向,当汇聚型断层面转折带的坡度小于33。时,油气易在古近系地层成藏;反之,油气易在新近系地层成藏;而复合型断层面以座椅式为主,油气易被封堵在古近系并在座椅面附近及以下成藏。该研究对油气分布的预测具有一定的指导意义。
Numerical Study of Combining Steady Vortex Generator Jets and Deflected Trailing Edge to Reduce the Blade Numbers of Low Pressure Turbine Stage

A flow control system that combined steady Vortex Generator Jets and Deflected Trailing-edge (VGJs-DT) to decrease the low pressure turbine (LPT) blade numbers was presented. The effects of VGJs-DT on energy loss and flow of low solidity low pressure turbine (LSLPT) cascades were studied. VGJs-DT was found to decrease the energy loss of LSLPT cascade and increase the flow turning angle. VGJs-DT decreased the solidity by 12.5% without a significant increase in energy loss. VGJs-DT was more effective than steady VGJs. VGJs-DT decreased the energy loss and increased the flow angle of the LSLPT cascade with steady VGJs. VGJs-DT can use 50% less mass flow than steady VGJs to inhibit the flow separation in the LSLPT cascade. The deflected trailing edge enhanced the ability of steady VGJs to resist flow separation. Overall, VGJs-DT can be used to control flow separation in LPT cascade and reduce the blade numbers of low pressure turbine stage.
Activity coefficient and solubility of yttrium in Fe-Y dilute solid solution

The density functional theory (DFT) and density functional perturbation theory (DFPT) within the quasi-harmonic approximation were employed to investigate the activity coefficient of Y in dilute Fe-Y solid solution. The ground states of Fe-Y compounds and the thermodynamic properties of bcc Fe were calculated, and the stable and metastable structures of Fe-Y compounds were predicted as well. With the temperature increasing, the Y activity coefficient in bcc Fe matrix increased rapidly, and the interaction between Y and Fe became more favorable. Based on the calculated thermodynamic properties, the solubility of Y in bcc Fe matrix as a function of temperature was predicted, and compared with the experimental data.
聚醚醚酮涂层的制备与应用进展

聚醚醚酮(PEEK)作为一种特种工程塑料,其涂层具有良好的绝缘性和耐腐蚀性,在腐蚀防护领域具有广阔的前景。阐述了PEEK的性能,重点介绍了PEEK涂层制备方法和改性研究,结合PEEK涂层的应用情况,对其在海洋腐蚀环境下的应用进行了展望。
SiO_2包覆铝粉的合成及其应用

以正硅酸乙酯(TEOS)为前驱体,采用溶胶-凝胶法制备SiO_2包覆铝粉。利用红外光谱、激光粒度分析仪、X射线衍射仪和扫描电镜等手段,对所制备样品的物相结构、表面形貌和粒径进行表征。将所制备的SiO_2包覆铝粉用于电沉积Ni-Co-Al复合镀层。结果表明:原料铝粉发生严重的团聚现象,在0.1 mol/L盐酸和去离子水溶液中都产生较大的析氢量;SiO_2包覆铝粉的析氢量几乎为零,具有较好的分散性;在酸性镍钴镀液中添加SiO_2包覆铝粉获得了铝含量高的Ni-Co-Al复合镀层。该镀层在900 ℃有良好的抗氧化性能,可用作高温环境下工作的零部件的表面防护镀层。
船用铜质海水冷却设备的牺牲阳极阴极保护

为提高船用铜质海水冷却设备的腐蚀安全性,采用极化曲线、腐蚀仿真计算和样机腐蚀试验方法综合研究了船用铜质海水冷却设备牺牲阳极的阴极保护行为。结果表明:海水环境下铁合金牺牲阳极与铜合金开路电位差值合理,在提供充分的阴极保护驱动电位的前提下,能够有效降低阳极材料的溶解速率,比锌合金阳极更适合于铜合金的阴极保护;Fe-Mn-Cr合金阳极可以在保证铜合金阴极保护效果的基础上,有效提高自身服役寿命,可靠性优于现役的Zn-Al-Cd合金阳极,具有良好的工程应用价值。
快离子导体La_(0.8)Sr_(0.2)MnO_3包覆LiMn_2O_4正极材料的结构和电化学性能

为进一步提高动力电池正极材料锰酸锂(LiMn_2O_4)的循环稳定性,通过溶胶-凝胶法用快离子导体La_(0.8)Sr_(0.2)MnO_3作为包覆材料对LiMN_2O_4进行表面修饰,探讨了不同包覆量对复合材料电化学性能的影响。采用X射线衍射仪(XRD)、场发射扫描电镜(FESEM)和透射电子显微镜(TEM)对样品的微观结构以及形貌进行表征。结果表明:La_(0.8)Sr_(0.2)MnO_3的包覆并没有改变LiMn_2O_4晶体结构及空间构型;相比纯的LiMn_2O_4样品,La_(0.8)Sr_(0.2)MnO_3包覆后的样品颗粒表面较为粗糙;涂层为薄膜状结构,均匀且完全包覆在LiMn_2O_4颗粒的表面。利用电化学测试方法测试其电化学性能,测试结果表明,当La_(0.8)Sr_(0.2)O_3包覆量为5%时,具有较好的电化学性能,首次放电比容量为127.4 mA · h/g(0.1 C), 25 ℃循环400次后容量保持率为91.2%,55 ℃循环100次后容量保持率为91.1%;与未经表面修饰的样品相比,其首次放电比容量为119.1 mA · h/g(0.1 C),400次的容量保持率为61.9%,100次容量保持率为77.9%,La_(0.8)Sr_(0.2)MO_2包覆后的样品的电化学性能尤其是循环性能得到明显的提高。
伴IgG4阳性浆细胞增多的脑膜Rosai-Dorfman病一例

本例组织学特征及免疫组织化学表型均支持IgG4阳性浆细胞增多的脑膜RDD的诊断,提示二者密切相关。发生于脑膜的疾病要想到RDD的可能,也要想到伴有IgG4阳性浆细胞增多或IgG4相关性疾病的可能。
Differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection

Patients with extremely severe oligozoospermia (ESO) and cryptozoospermia (CO) are suitable using intracytoplasmic sperm injection (ICSI) as an infertility treatment. However, some andrologists are confused to distinguish ESO and CO in clinic diagnose. This study was designed for the first time to evaluate and compare patients with ESO and CO to determine whether these are useful clinical distinctions. A total of 270 infertile men in our center were classified into four groups as Group nonobstruction azoospermia (NOA, n = 44), Group ESO (n = 78), Group CO (n = 40), and Group obstruction azoospermia (OA, n = 108). Comparisons of the volume of bilateral testes, the level of follicle stimulating hormone (FSH) and inhibin B were obtained in four groups. Then comparisons of fertilization rates, cleavage rate,and excellent embryos rate were obtained when couples performed ICSI. All indexes (volume of bilateral testis, level of FSH and inhibin B) in Groups ESO and CO were no difference,while Groups OA versus NOA, OA versus ESO, and OA versus CO were significant differences (P < 0.05). The rates of fertilization were no differences in Groups ESO and CO while Groups OA versus ESO, OA versus CO were significant differences (P< 0.05). Therefore,the spermatogenic functions in patients with CO and ESO were similar, better than NOA but worse than OA. However,it would be helpful to evaluate their spermatogenesis using testicular biopsies, especially accompanied azoospermia in clinical practice.
Normozoospermic versus teratozoospermic domestic cats: differential testicular volume,sperm morphometry, and subpopulation structure during epididymal maturation

Teratozoospermia (<40% morphologically normal spermatozoa/ejaculate) is a frequent phenomenon in feline species. This research was carried out to study the possible differences in testicular volume, differential sperm morphometric traits,and potential differences regarding the sperm subpopulational structure during epididymal sperm maturation in teratozoospermic feline donors. Epididymal sperm samples were collected from the caput (R1), corpus (R2), and cauda (R3) epididymidis in two donor groups (N: normozoospermic; T: teratozoospermic). Aliquots were assessed for concentration, viability, motility, and acrosomal integrity. Sperm morphometric descriptors from CASA-Morph analysis were analyzed by the Principal Component Analysis (PCA) and clustering analyses. Irrespective of the group analyzed, PCA revealed two Principal Components (PCs) for each epididymal region explaining more than the 93% of the variance. Surprisingly,the number of subpopulations remained constant in regions R1-R2-R3 irrespective of the donor group analyzed. However,the distribution of these subpopulations was found to be structurally different and strongly influenced by the epididymal region and the donor group. In conclusion, testicular morphometry and the sperm subpopulation structure were different in N and T donors. The alterations in subpopulations during epididymal maturation could be used as a potential clinical indicator of teratozoospermic individuals since an important influence of teratozoospermia on sperm subpopulation structure has been demonstrated.
The effects of fresh and rapid desiccated tissue on estimates of Ophiopogoneae genome size

Fresh plant material is usually used for genome size estimation by flow cytometry (FCM). Lack of fresh material is cited as one of the main reasons for the dearth of studies on plants from remote locations. Genome sizes in fresh versus desiccated tissue of 16 Ophiopogoneae species and five model plant species were estimated. Our results indicated that desiccated tissue was suitable for genome size estimation; this method enables broader geographic sampling of plants when fresh tissue collection is not feasible. To be useful, after dessication the Ophiopogoneae sample should be green without brown or yellow markings; it should be stored in deep freezer at -80 ℃, and the storage time should be no more than 6 months.
Late Pliocene diversity and distribution of Drynaria (Polypodiaceae) in western Yunnan explained by forest vegetation and humid climates

The palaeodiversity of flowering plants in Yunnan has been extensively interpreted from both a molecular and fossil perspective. However, for cryptogamic plants such as ferns, the palaeodiversity remains poorly known. In this study, we describe a new ferny fossil taxon, Drynaria lanpingensis sp. nov. Huang, Su et Zhou (Polypodiaceae), from the late Pliocene of northwestern Yunnan based on fragmentary frond and pinna with in situ spores. The frond is pinnatifid and the pinnae are entirely margined. The sori are arranged in one row on each side of the primary vein. The spores have a semicircular to bean-shaped equatorial view and a tuberculate surface. Taken together with previously described fossils, there are now representatives of three known fossil taxa of Drynaria from the late Pliocene of western Yunnan. These finds suggest that Drynaria diversity was considerable in the region at that time. As Drynaria is a shade-tolerant plant, growing preferably in wet conditions in the understory of forests, its extensive existence may indicate forest vegetation and humid climates in western Yunnan during the late Pliocene. This is in line with results from floristic investigations and palaeoclimatic reconstructions based on fossil floras.
Molecular phylogeny reveals the non-monophyly of tribe Yinshanieae (Brassicaceae) and description of a new tribe, Hillielleae

The taxonomic treatment within the unigeneric tribe Yinshanieae (Brassicaceae) is controversial, owing to differences in generic delimitation applied to its species. In this study, sequences from nuclear ITS and chloroplast trnL-F regions were used to test the monophyly of Yinshanieae, while two nuclear markers (ITS, ETS) and four chloroplast markers (trnL-F, trnH-psbA, rps16, rpL32-trnL) were used to elucidate the phylogenetic relationships within the tribe. Using maximum parsimony, maximum likelihood, and Bayesian inference methods, we reconstructed the phylogeny of Brassicaceae and Yinshanieae. The results show that Yinshanieae is not a monophyletic group, with the taxa splitting into two distantly related clades: one clade contains four taxa and falls in Lineage I, whereas the other includes all species previously placed in Hilliella and is embedded in the Expanded Lineage II. The tribe Yinshanieae is redefined, and a new tribe, Hillielleae, is proposed based on combined evidence from molecular phylogeny, morphology, and cytology.
Optimizing back surface field for improving V_(oc) of (Al)GaInP solar cell

GaInP and AlGaInP solar cells were grown by metal organic chemical vapor deposition (MOCVD), and theoretical analysis demonstrated that hetero-interface recombination velocity plays an important role in the optimizing of cell performance, especially the interface between base layer and back surface field (BSF). Measurements including lattice-matched growth and pseudo-BSF were taken to optimize BSF design. Significant improvement of V_(oc) in GaInP and AlGaInP solar cells imply that the measures we took are effective and promising for performance improvement in the next generation high efficiency solar cells.
Load adaptive start-up scheme for synchronous boost DC–DC converter

This paper presents a load adaptive soft-start scheme through which the inductor current of the synchronous boost DC–DC converter can trace the load current at the start-up stage. This scheme effectively eliminates the inrush-current and over-shoot voltage and improves the load capability of the converter. According to the output voltage, the start-up process is divided into three phases and at each phase the inductor current is limited to match the load. In the pre-charge phase, a step-increasing constant current gives a smooth rise of the output voltage which avoids inrush current and ensures the converter successfully starts up at different load situations. An additional ring oscillator operation phase enables the converter to start up as low as 1.4 V. When the converter enters into the system loop soft-start phase, an output voltage and inductor current detection methods make the transition of the phases smooth and the inductor current and output voltage rise steadily. Effective protection circuits such as short-circuit protection, current limit circuit and over-temperature protection circuit are designed to guarantee the safety and reliability of the chip during the start-up process. The proposed start-up circuit is implemented in a synchronous boost DC–DC converter based on TSMC 0.35 μm CMOS process with an input voltage range 1.4–4.2 V, and a steady output voltage 5 V, and the switching frequency is 1 MHz. Simulation results show that inrush current and overshoot voltage are suppressed with a load range from 0–2.1 A, and inductor current is as low as 259 mA when the output shorts to the ground.
Steady-state solution growth of microcrystalline silicon on nanocrystalline seed layers on glass

The growth of polycrystalline silicon layers on glass from tin solutions at low temperatures is presented. This approach is based on the steady-state solution growth of Si crystallites on nanocrystalline seed layers, which are prepared in a preceding process step. Scanning electron microscopy and atomic force microscopy investigations reveal details about the seed layer surfaces, which consist of small hillocks, as well as about Sn inclusions and gaps along the glass substrate after solution growth. The successful growth of continuous microcrystalline Si layers with grain sizes up to several ten micrometers shows the feasibility of the process and makes it interesting for photovoltaics.
Computation of sensitivities of IC interconnect parasitic capacitances to the process variation with dual discrete geometric methods

Sensitivity analysis methods help to deal with the challenges of process variation in extraction of parasitic capacitances in an integrated circuit. The dual discrete geometric methods (DGMs), which have been recently utilized to extract parasitic capacitances, are reviewed. The computation method based on the dual DGMs for sensitivities of capacitances with respect to the given process parameters is presented. As the dual DGMs utilize scalar electric potential is unknown, the capacitances are obtained effectively, and then the sensitivities are calculated conveniently.
Development of 17 kV 4H-SiC PiN diode

The design, fabrication, and electrical characteristics of a 4H-SiC PiN diode with breakdown voltage higher than 17 kV are presented. The three-zone JTE has been used in the fabrication. Numerical simulations have been performed to optimize the parameters of the edge termination technique. The epilayer properties of the N-type are 175 μm with a doping of 2 × 10~(14) cm~(-3). With the three-zone JTE, a typical breakdown voltage of 17 kV has been achieved.
The establishment of reliability model for LED lamps

In order to verify which of the distributions and established methods of reliability model are more suitable for the analysis of the accelerated aging of LED lamp, three established methods (approximate method, analytical method and two-stage method) of reliability model are used to analyze the experimental data under the condition of the Weibull distribution and Lognormal distribution, in this paper. Ten LED lamps are selected for the accelerated aging experiment and the luminous fluxes are measured at an accelerated aging temperature. AIC information criterion is adopted in the evaluation of the models. The results show that the accuracies of the analytical method and the two-stage method are higher than that of the approximation method, with the widths of confidence intervals of unknown parameters of the reliability model being the smallest for the two-stage method. In a comparison between the two types of distributions, the accuracies are nearly identical.
Photovoltaic performance of hybrid ITO/PEDOT:PSS/n-SnS/Al solar cell structure

The present paper discusses the performance of ITO/PEDOT:PSS/n-SnS/Al structured solar cells fabricated by thermal evaporation. The performance characterizing parameters such as the open circuit voltage, short circuit current density, series resistance, parallel resistance, ideality factor and the overall efficiency were found to be dependent on the SnS grain size in the nano-meter regime and incident light intensity. The experimental work directly reconfirms the theoretical results and ideas raised in the literature by early researchers.
Identification of a TSPY co-expression network associated with DNA hypomethylation and tumor gene expression in somatic cancers

Testis specific protein Y-encoded (TSPY) is a Y-located proto-oncogene predominantly expressed in normal male germ cells and various types of germ cell tumor. Significantly, TSPY is frequently expressed in somatic cancers including liver cancer but not in adjacent normal tissues, suggesting that ectopic TSPY expression could be associated with oncogenesis in non-germ cell cancers. Various studies demonstrated that TSPY expression promotes growth and proliferation in cancer cells; however, its relationship to other oncogenic events in TSPY-positive cancers remains unknown. The present study seeks to correlate TSPY expression with other molecular features in clinical cancer samples, by analyses of RNA-seq transcriptome and DNA methylation data in the Cancer Genome Atlas (TCGA) database. A total of 53 genes, including oncogenic lineage protein 28 homolog B (LIN28B) gene and RNA-binding motif protein Y-linked (RBMY) gene, are identified to be consistently co-expressed with TSPY, and have been collectively designated as the TSPY co-expression network (TCN). TCN genes were simultaneously activated in subsets of liver hepatocellular carcinoma (30%) and lung adenocarcinoma (10%) regardless of pathological stage, but only minimally in other cancer types. Further analysis revealed that the DNA methylation level was globally lower in the TCN-active than TCN-silent cancers. The specific expression and methylation patterns of TCN genes suggest that they could be useful as biomarkers for the diagnosis, prognosis and clinical management of cancers, especially those for liver and lung cancers, associated with TSPY co-expression network genes.
Cebpα is essential for the embryonic myeloid progenitor and neutrophil maintenance in zebrafish

In vertebrates, myeloid cells arise from multiple waves of development: the first or embryonic wave of myelopoiesis initiates early from non-hematopoietic stem cell (HSC) precursors and gives rise to myeloid cells transiently during early development; whereas the second or adult wave of myelopoiesis emerges later from HSCs and produces myeloid cells continually during fetal and adult life. In the past decades, a great deal has been learnt about the development of myeloid cells from adult myelopoiesis, yet the genetic network governing embryonic myelopoiesis remains poorly defined. In this report, we present an in vivo study to delineate the role of Cebpα during zebrafish embryonic myelopoiesis. We show that embryonic myelopoiesis in cebpa-deficient zebrafish mutants initiates properly but fails to produce macrophages and neutrophils. The lack of macrophages and neutrophils in the mutants is largely attributed to the cell cycle arrest of embryonic myeloid progenitors, resulting in the impairment of their maintenance and subsequent differentiation. We further show that Cebpα, perhaps acting cooperatively with Runx1, plays a critical role in embryonic neutrophil maintenance. Our findings reveal a new role of Cebpα in embryonic myelopoiesis.
The biological potentials of substituted 1,2-diazines: a review on versatile pyridazine derivatives

Many studies have been performed on the pyridazine(1,2-diazine) derivatives in the past decade. This heterocyclic nucleus possesses almost all types of pharmacological activities. This small and simple pyridazine nucleus is present in various compounds that are involved in the research aiming to evaluate new compounds with interesting biological activities, including anti-bacterial, anti-fungal, anti-viral, analgesic, anti-inflammatory, anti-platelets, anti-ulcer, anti-secretory, anti-depressants, anxiolytics, sedative-hypnotics, anti-convulsant, anti-tumor, anti-thrombotics, cardiotonics, vasodilatators, anti-arrhythmics, anti-diabetic, anti-tubercular agents and so on. This review focuses on the pyridazine derivatives with potential activities that have been developed. Pyridazine compounds draw attention of scientists and researchers because of their diverse biological activities as well as simple chemical and easy functionalization at various ring positions, making them attractive synthetic building blocks for designing and development of novel pyridazinone-based therapeutic agents.
Mixed convection flow of jeffrey nanofluid with thermal radiation and double stratification

This article addresses the two-dimensional laminar boundary layer flow of magnetohydrodynamic (MHD) Jeffrey nanofluid with mixed convection. Effects of thermal radiation, thermophoresis, Brownian motion and double stratifications are taken into account. Rosseland's approximation is utilized for the thermal radiation phenomenon. Convergent series solutions of velocity, temperature and nanoparticle concentration are developed. Graphs of dimensionless temperature and nanoparticle concentration are presented to investigate the influences of different emerging parameters. The values of skin-friction coefficient, local Nusselt and Sherwood numbers are computed and discussed for both Jeffrey and viscous fluids cases. We have observed that the temperature profile retarded for the larger values of Deborah number while an enhancement is noticed with the increasing values of ratio of relaxation to retardation times. Increasing values of thermal and nanoparticle concentration stratifications lead to a reduction in the temperature and nanoparticle concentration. The values of local Nusselt and Sherwood numbers are larger for the viscous fluid case when compared with Jeffrey fluid.
右侧上颌第二磨牙畸形中央尖1例

畸形中央尖又称牙外突,是一种牙体形态发育畸形,临床上主要表现为牙面额外突出的牙尖或结节,好发于前磨牙,磨牙较少发生。作者在2014年上海市松江区中小学生健康体检工作中发现1例上颌第二磨牙畸形中央尖,现报道如下.