mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
The effect of annealing temperature and the characteristics of p-n junction diodes based on sprayed polyaniline/ZnO thin films

Polyaniline,ZnO and polyaniline/ZnO nanocomposite thin films are coated on glass substrates using the spray pyrolysis technique.The samples are characterized by the XRD,SEM,EDAX,UV-Vis and I-V characteristics. The XRD analyses confirm that the spray-coated polyaniline and ZnO thin films have orthorhombic and hexagonal structures,respectively,and optical bandgap energy decreases from 3.81 to 3.41 eV with the addition of a Zn atom.SEM analysis of the polyaniline/ZnO nanocomposite thin films shows that there is an agglomeration of ZnO particles with uniform distribution in the polyaniline matrix,and the diode characteristics of the polyaniline /ZnO nanocomposite show weak rectification behavior.Parameters such as the ideality factor,reverse saturation current and barrier height are calculated from the I-V characteristics.
High-Q micro-ring resonators and grating couplers for silicon-on-insulator integrated photonic circuits

An ultra-small integrated photonic circuit has been proposed,which incorporates a high-quality-factor passive micro-ring resonator(MR) linked to a vertical grating coupler on a standard silicon-on-insulator(SOI) substrate.The experimental results demonstrate that the MR propagation loss is 0.532 dB/cm with a 10μm radius ring resonator,the intrinsic quality factor is as high as 202.000,the waveguide grating wavelength response curve is a 1 dB bandwidth of 40 nm at 1540 nm telecommunication wavelengths,and the measured fiber-to-fiber coupling loss is 10 dB.Furthermore,the resonator wavelength temperature dependence of the 450 nm wide micro-ring resonator is 54.1 pm/℃.Such vertical grating coupler and low loss MR-integrated components greatly promote a key element in biosensors and high-speed interconnect communication applications.
Insights into the structural biology of G-protein coupled receptors impacts drug design for central nervous system neurodegenerative processes

In the last few years, there have been important new insights into the structural biology of G-protein coupled receptors. It is now known that al osteric binding sites are involved in the affinity and selec-tivity of ligands for G-protein coupled receptors, and that signaling by these receptors involves both G-protein dependent and independent pathways. The present review outlines the physiological and pharmacological implications of this perspective for the design of new drugs to treat disorders of the central nervous system. Specifical y, new possibilities are explored in relation to al osteric and orthosteric binding sites on dopamine receptors for the treatment of Parkinson’s disease, and on muscarinic receptors for Alzheimer’s disease. Future research can seek to identify ligands that can bind to more than one site on the same receptor, or simultaneously bind to two receptors and form a dimer. For example, the design of bivalent drugs that can reach homo/hetero-dimers of D2 dopa-mine receptor holds promise as a relevant therapeutic strategy for Parkinson’s disease. Regarding the treatment of Alzheimer’s disease, the design of dualsteric ligands for mono-oligomeric musca-rinic receptors could increase therapeutic effectiveness by generating potent compounds that could activate more than one signaling pathway.
Acetylcholine secretion by motor neuron-like cells from umbilical cord mesenchymal stem cells

Umbilical cord mesenchymal stem cel s were isolated by a double enzyme digestion method. The third passage of umbilical cord mesenchymal stem cel s was induced with heparin and/or basic fi-broblast growth factor. Results confirmed that cel morphology did not change after induction with basic fibroblast growth factor alone. However, neuronal morphology was visible, and microtu-bule-associated protein-2 expression and acetylcholine levels increased fol owing induction with heparin alone or heparin combined with basic fibroblast growth factor. Hb9 and choline acetyl-transferase expression was high fol owing inductive with heparin combined with basic fibroblast growth factor. Results indicate that the inductive effect of basic fibroblast growth factor alone was not obvious. Heparin combined with basic fibroblast growth factor noticeably promoted the differen-tiation of umbilical cord mesenchymal stem cel s into motor neuron-like cel s. Simultaneously, um-bilical cord mesenchymal stem cel s could secrete acetylcholine.
日本养老机构服务质量评价研究进展及其对我国的启示

随着全球老龄人口数量的增长,有效满足养老服务需求、缓解老龄化对医疗机构造成的压力已经成为各国家必须面对的难题。人口高龄化、失能失智老人骤增使为老人提供专业护理服务的养老机构的作用与价值突显,其一定程度上的替代作用使得医疗机构的负担减小,服务利用率提高。日本是老龄化最为严重的国家之一,2010年日本65岁以上老龄人口比例占总数的22.84%。为了有效应对严峻的养老问题,顺应社会化养老的发展趋势,日本自21世纪初开始实行全民性长期护理保险(Long-Term Care Insurance,LTCI)制度。实践证明,长期护理保险能有效降低医疗成本,使老人得到政府及社会的高度重视,实现了养老资源利用全民均等、高效和统一管理。日本养老机构依托长期护理保险制度迅速发展,其完善的质量评价体系对于养老机构服务效率与质量提升起到了巨大推动作用。我国与日本都是以家庭养老为基础的东方国家,在人口结构、老龄化进程等方面有诸多相似。但是,由于我国老龄化超前于经济发展,养老资源受到经济发展和社会资源利用均衡化较差等条件的限制,确保在现有政策体制下,实现养老资源的公平、有效利用,争取投入与产出的最优化显得尤为重要。构建完善的养老服务质量评价体系,可以通过监管和评价来保证养老资源利用的效率和效果。因此,借鉴日本养老机构的管理经验、机构质量管理与质量评价的核心理念,将其转化为符合我国实际情况的管理制度与评价标准,对于实现我国养老机构科学化管理与评价具有深远的指导意义。
妊娠晚期妇女睡眠障碍及护理干预研究进展

睡眠障碍是妊娠期妇女常见的症状之一，尤以妊娠晚期常见，主要表现为夜间觉醒次数增多、睡眠呼吸暂停综合征、日间嗜睡、不宁腿综合征等。孕期睡眠障碍给家庭和社会带来很多不利的影响，影响胎儿生长发育，增加产后并发症；严重者导致认知功能障碍以及其他频繁的事故发生。本文将妊娠期妇女睡眠障碍相关问题综述如下。
人性化管理的内涵——访浙江大学医学院附属邵逸夫医院院长何超

在浙江大学医学院附属邵逸夫医院(以下简称"邵逸夫医院")第七届国际学术周暨2012护理国际研讨会上,我们见到了邵逸夫医院的院长、肿瘤学教授——何超。何超是一位成功的院长,在他的带领下,邵逸夫医院成为我国首家通过美国医疗机构评审国际联合委员会(JCI)认证的医院,邵逸夫医院也因此在医疗界声名鹊起。何超曾在美国德州西南医学中心作访问学者研习大肠癌治疗,在美国西弗吉尼亚大学医学院作访问学者研习医院管理,曾就读于上海中欧国际管理学院的医院管理MBA 研修班,独特的经历造就了这位集学者、管理者、企业家于一身的院长。
胃体神经内分泌瘤2例诊治体会

综上所述:(1)内镜下息肉样的病变可能最终并非息肉,应尽量取活检证实病理性质,多发部位者需分部位活检明确,便于决定治疗方式,若当成良性病变草率处理可能导致误诊而忽视。(2)早期GEP-NEN可做内镜下黏膜剥离术、黏膜切除术或局部切除方式达到治愈,术前需尽量完善超声内镜、CT、体表超声等检查以确保无相关部位的淋巴结肿大,若发现淋巴结,即使是微肿瘤也需外科手术治疗,同时若切缘阳性、有血管浸润、包膜不完整等危险因素仍需追加外科手术。(3)因GEP-NEN少见,虽第1例有完善全身PET,第2例有完善激光共聚焦和NBI胃镜,但目前关于上述检查对其诊断是否有价值仍需进一步临床实践中去探索和总结。
Design of Adaptive Robust Guaranteed Cost Controller for Wind Power Generator

According to the increasing requirement of the wind energy utilization and the dynamic stability in the variable speed variable pitch wind power generation system, a linear parameter varying (LPV) system model is established and a new adaptive robust guaranteed cost controller (AGCC) is proposed in this paper. First, the uncertain parameters of the system are estimated by using the adaptive method, then the estimated uncertain parameters and robust guaranteed cost control method are used to design a state feedback controller. The controller s feedback gain is obtained by solving a set of linear matrix inequality (LMI) constraints, such that the controller can meet a quadratic performance evaluation criterion. The simulation results show that we can realize the goal of maximum wind energy capture in low wind speed by the optimal torque control and constant power control in high wind speed by variable pitch control with good dynamic characteristics, robustness and the ability of suppressing disturbance.
H_∞ Robust Control of DC-AC Interfaced Microsource in Microgrids

This paper focuses on the direct current-alternating current (DC-AC) interfaced microsource based H_∞ robust control strategies in microgrids. It presents detail of a DC-AC interfaced microsource model which is connected to the power grid through a controllable switch. A double loop current-regulated voltage control scheme for the DC-AC interface is designed. In the case of the load disturbance and the model uncertainties, the inner voltage and current loop are produced based on the H_∞ robust control strategies. The outer power loop uses the droop characteristic controller. Finally, the scheme is simulated using the Matlab/Simulink. The simulation results demonstrate that DC-AC interfaced microsource system can supply high quality power. Also, the proposed control scheme can make the system switch smoothly between the isolated mode and grid-connected mode.
State Feedback Tracking Control for Indirect Field-oriented Induction Motor Using Fuzzy Approach

This paper deals with the synthesis of fuzzy controller applied to the induction motor with a guaranteed model reference tracking performance. First, the Takagi-Sugeno (T-S) fuzzy model is used to approximate the nonlinear system in the synchronous d-q frame rotating with field-oriented control strategy. Then, a fuzzy state feedback controller is designed to reduce the tracking error by minimizing the disturbance level. The proposed controller is based on a T-S reference model in which the desired trajectory has been specified. The inaccessible rotor flux is estimated by a T-S fuzzy observer. The developed approach for the controller design is based on the synthesis of an augmented fuzzy model which regroups the model of induction machine, fuzzy observer, and reference model. The gains of the observer and controller are obtained by solving a set of linear matrix inequalities (LMIs). Finally, simulation and experimental results are given to show the performance of the observer-based tracking controller.
星状神经节阻滞治疗突发性耳聋的疗效观察

在疼痛门诊工作中,经常遇到因突发性耳聋而就医的患者,突发性耳聋是疼痛科及耳鼻咽喉科临床常见的急症之一,早在1944年就有临床报道[1],是指突然发生的,在数分钟、数小时或3 d以内出现的感音神经性听力损失,至少在相邻的2个频率听力下降20 dB以上。常伴有耳鸣、眩晕等症状,多单耳发病,其病因尚不明确。
小儿静脉留置针固定方法的改进

静脉留置针又称套管针,是由先进的生物材料制成,具有较好的生物相容性,可有效留置现已广泛应用于临床。尤其是儿科,作为头皮钢针的换代产品应用于患儿输液中,能有效避免反复穿刺的痛苦,减轻护士工作量,提高护理工作效率。但由于患儿好动,不能控制自己的行为,留置针易受身体及衣服的摩擦而带出,给临床固定带来困难,增加患儿的痛苦。针对此情况,我科改进小儿静脉留置针固定方法,取得满意效果,报告如下。
护理绩效奖金核算改革初探

目的探讨护理人员绩效奖金的核算方法及效果。方法以护理工作内容与护理时数为评估系统,对临床护理的护理绩效奖金进行改革。病房护理绩效奖金=护理费+护理治疗费+(床日总量+入院人数×3+出院人数×3)×护理时数-基本工资-可控成本×0.5-折旧×0.1。以胸外科、血液科为例,比较改革前后奖金增幅情况。结果改革后胸外科护理人员个人奖金增加32.1%,血液科增加26.1%。结论改革后各护理单元人均奖金有不同程序的增幅。护理人员绩效改革体现了各护理单元的劳动强度、技术水平、服务意识,实现按岗位、按质量标准、技术水平分配,有利于激发护理人员的工作积极性和主动性。
品管圈活动降低白血病化疗后骨髓抑制期PICC感染

目的探讨开展品管圈活动对降低急性白血病化疗后骨髓抑制期PICC感染的作用。方法成立品管圈活动小组,确立"降低急性白血病患者骨髓抑制期PICC感染率"为活动课题,对活动前急性白血病化疗后骨髓抑制期PICC感染问题进行要因分析,制定并落实质量改进措施,再开展活动。结果患者化疗后骨髓抑制期PICC穿刺点红肿、静脉炎、导管相关血流感染较活动前显著降低(P<0.05,P<0.01)。结论品管圈活动可有效降低急性白血病化疗后骨髓抑制期PICC感染,提高导管的使用效率。
射频消融治疗阵发性心房颤动术中的药物监护

目的总结经导管射频消融阵发性心房颤动术中药物应用护理经验。方法30例经导管射频消融阵发性心房颤动患者术中遵医嘱运用镇痛、抗凝、激发试验等药物,密切观察药物的疗效及反应。结果所有患者均获得满意镇痛;肝素抗凝过程中无出血,1例导管顶端有血栓形成,加大肝素用量后完成消融;3例发生异常迷走神经反射,立即停止异丙肾上腺素输入,予阿托品0.5mg静脉注射后心率、血压恢复正常;三磷酸腺苷注射中所有患者都有一过性胸闷,3例患者出现窦性停搏或房室传导阻滞,经紧急起搏后转危为安。结论护士需掌握药物剂量、方法、作用与不良反应,准确用药,为手术顺利进行提供安全保障。
正交试验优选人参皂苷Rg_1的增溶研究

目的优选人参皂苷Rg_1的增溶条件。方法采用HPLC法测定人参皂苷Rg_1的量,设计L_9(3~4)正交试验考察不同浓度的羟丙基-β-环糊精、聚维酮、泊洛沙姆和搅拌时间对人参皂苷Rg_1增溶效果的影响。结果人参皂苷Rg_1增溶效果较好的物质为羟丙基-β-环糊精,质量分数10%,搅拌时间12 h。结论羟丙基-β-环糊精使人参皂苷Rg_1溶解度增加较大。
HPLC-ELSD法测定复方枇杷止咳颗粒中桔梗皂苷D、熊果酸、齐墩果酸和贝母素甲

目的应用高效液相色谱-蒸发光散射检测器法测定复方枇杷止咳颗粒中桔梗皂苷D、熊果酸、齐墩果酸和贝母素甲。方法 C_(18)色谱柱(4.6 mm×150 mm,5μm);体积流量1.0 mL/min;测定桔梗皂苷D以乙腈-水(26∶74)为流动相,ELSD漂移管温度95℃,载气(N2)体积流量2.9 SLPM/min;测定熊果酸和齐墩果酸以甲醇-水-冰乙酸-三乙胺(90∶10∶0.03∶0.06)为流动相,ELSD漂移管温度100℃,载气(N2)体积流量2.7 SLPM/min;测定贝母素甲以乙腈-水-二乙胺(75∶25∶0.5)为流动相,ELSD漂移管温度80℃,载气(N2)体积流量2.1 SLPM/min。结果桔梗皂苷D在0.081 3~1.626μg(r=0.999 9)进样量与峰面积呈良好的线性关系,平均加样回收率为98.29%,RSD为1.16%(n=6);熊果酸和齐墩果酸分别在0.075 3~1.506μg(r=0.999 5)、0.021 5~0.430μg(r=0.999 7)进样量与峰面积呈良好的线性关系,平均加样回收率分别为98.58%、97.79%,RSD(n=6)分别为1.33%、1.53%;贝母素甲在0.010 6~0.212 0μg(r=0.999 8)进样量与峰面积呈良好的线性关系,平均加样回收率为98.50%,RSD为1.73%(n=6)。结论该方法测定结果准确、灵敏、重复性好。
葛根素治疗早期2型糖尿病肾病的Meta分析

目的用循证医学方法 Meta分析评价葛根素治疗早期2型糖尿病肾病的临床效果及安全性。方法计算机及手工检索相关文献,由两名研究者按纳入与排除标准独立选择实验、交叉核对,评价质量、提取数据,并用RevMan5.0软件对数据进行分析。结果经筛选最终纳入9篇关于葛根素治疗早期2型糖尿病肾病的随机对照研究,与对照组相比,葛根素具有减少尿微量白蛋白、降低空腹血糖的作用并有统计学意义。结论葛根素治疗早期2型糖尿病肾病安全有效,尚有待开展高质量的多中心、随机、盲法、对照的临床研究进一步证实。
Variable-fidelity optimization with design space reduction

Advanced engineering systems, like aircraft, are defined by tens or even hundreds of design variables. Building an accurate surrogate model for use in such high-dimensional optimization problems is a difficult task owing to the curse of dimensionality. This paper presents a new algorithm to reduce the size of a design space to a smaller region of interest allowing a more accurate surrogate model to be generated. The framework requires a set of models of different physical or numerical fidelities. The low-fidelity (LF) model provides physics-based approximation of the high-fidelity (HF) model at a fraction of the computational cost. It is also instrumental in identifying the small region of interest in the design space that encloses the high-fidelity optimum. A surrogate model is then constructed to match the low-fidelity model to the high-fidelity model in the identified region of interest. The optimization process is managed by an update strategy to prevent convergence to false optima. The algorithm is applied on mathematical problems and a two-dimen-sional aerodynamic shape optimization problem in a variable-fidelity context. Results obtained are in excellent agreement with high-fidelity results, even with lower-fidelity flow solvers, while showing up to 39% time savings.
Sliding mode control of reaction flywheel-based brushless DC motor with buck converter

Reaction flywheel is a significant actuator for satellites’ attitude control. To improve output torque and rotational speed accuracy for reaction flywheel, this paper reviews the modeling and control approaches of DC-DC converters and presents an application of the variable structure system theory with associated sliding regimes. Firstly, the topology of reaction flywheel is constructed. The small signal linearization process for a buck converter is illustrated. Then, based on the state averaging models and reaching qualification expressed by the Lee derivative, the general results of the sliding mode control (SMC) are analyzed. The analytical equivalent control laws for reaction flywheel are deduced detailedly by selecting various sliding surfaces at electromotion, energy consumption braking, reverse connection braking stages. Finally, numerical and experimental examples are presented for illustrative purposes. The results demonstrate that favorable agreement is established between the simulations and experiments. The proposed control strategy achieves preferable rotational speed regulation, strong rejection of modest disturbances, and high-precision output torque and rotational speed tracking abilities.
膀胱副神经节瘤的诊治分析(附7例报告并文献复习)

膀胱副神经节瘤在临床上比较罕见，约占膀胱肿瘤的0.06%[1]。由于本病发病率低，临床医生及病理医师认识不足，因此在诊断的过程中容易被误诊，导致手术意外。现报道华中科技大学同济医学院附属荆州医院1990年4月至2012年5月收治的7例病例，结合中外文献资料，探讨本病的诊断与治疗特点，以供同道共识。
三氯乙烷污染环境中脱卤素杆菌的多样性

三氯乙烷(1,1,1-Trichloroethane,TCA)是一种易挥发的氯代烃,密度大于水,曾作为金属清洗剂和高效溶剂在工业上广泛应用。近年来三氯乙烷对环境及人类健康的危害引起人们的关注,其自然分解过程较为困难,在环境中的存在具有一定的持久性。由于不合理的排放和意外泄漏等原因,三氯乙烷已成为地下水中最普遍的污染物之一,严重威胁生态系统和人体健康,是美国环保署(EPA)所确定的优先污染物。研究表明,Peptococcaceae科的脱卤素杆菌属(Dehalobacter)细菌纯培养物或含有Dehalobacter 的混合培养物可催化三氯乙烷及1,1,-二氯乙烷还原脱氯, 在其降解过程中起关键作用, 并可利用含有Dehalobacter 的菌群对三氯乙烷污染场地进行生物治理, 其中Dehalobacter 16S rRNA 基因的特异性探针被用作生物标记物来评价三氯乙烷污染场地的生物降解潜能。迄今为止, 已分离的3株Dehalobacter 菌株中, 仅D. restrictus str. TCA1能降解三氯乙烷。虽然城市污泥、地下深层土壤和地下水, 及产甲烷菌群[8]对三氯乙烷具有一定生物转化的能力, 但未对这些环境进行三氯乙烷降解菌群多样性分析, 包括针对Dehalobacter 的定量分析和多样性分析。
近红外光谱学与化学计量学在中成药液体制剂过程分析中的应用

近红外光谱技术是一种快速、无损的分析方法,化学计量学可以用于复杂数据的分析处理。将近红外光谱技术与化学计量学结合,可以作为中药制药过程控制的一种强有力的工具。近年来,近红外光谱技术已经较为广泛地应用于中药制药过程控制或在线监测。将重点介绍化学计量学和近红外光谱技术在中成药液体制剂方面的应用进展,主要应用领域包括:定性、定量分析方法和中成药液体制剂生产过程监控。
中国小麦生产管理技术发展战略探讨

初步探讨了小麦生产管理技术的建立、演变、现状、问题及发展的总体目标;并从创新集成综合生产管理技术体系,加强前瞻性栽培理论与技术研究,加强农机农艺结合的全程机械化研究,加强抗逆减灾研究,强化小麦产品安全及可持续生产研究等方面探讨了小麦生产管理技术发展思路。从适应多种生产形式,促进管理技术现代化,加强服务体系建设,保障管理技术落实到位等方面探讨了小麦生产管理技术发展方向。
肺隔离症弹簧圈介入栓塞治疗一例

讨论肺隔离症按与脏胸膜的关系，临床上分为叶内型和叶外型，叶内型位于脏层胸膜组织内，其囊腔病变与正常的支气管相通或不相通，临床多见；叶外型被自身胸膜包盖，独立于正常肺组织之外，囊腔与正常支气管不相通。其临床症状以反复发热、咳嗽、胸痛、咳脓痰甚至咳脓血痰等肺部感染症状为主，因其缺乏典型的临床症状，给确诊带来一定的困难。血管造影是诊断肺隔离症的传统方法， 具有很高的特异性，是肺隔离症诊断的金标准。
苏鲁造山带的构造格局与演化:来自苏鲁超高压带浅变质岩的制约

苏鲁超高压带内部及其北缘广泛发育以绿片岩相为代表的新元古界浅变质岩系,如超高压带内部石桥浅变质岩,超高压带南部的海州群和超高压带北部的五莲群、蓬莱群以及鲁西地区的土门群等.其中五莲群和海州群具有扬子型新元古界岩石组合特征,以发育含磷、冰碛砾岩和双峰式火山岩为特征,碎屑锆石在这些地层中也记录了丰富的新元古代年龄信息;而鲁西土门群和胶北蓬莱群华北型新元古界在苏鲁地区以碎屑岩-碳酸盐岩为代表,其碎屑锆石在这些地层中记录了与华北基底变质岩相似的年代学信息.根据这些浅变质岩系的地质学和同位素年代学特征,我们对苏鲁造山带的构造格局,板块缝合线位置和大陆碰撞过程中的构造推覆提出了新的认识.
大别-苏鲁造山带超高压榴辉岩和脉体磷灰石含氯特征与变质流体演化

根据磷灰石中的氯组分含量,研究了大别-苏鲁超高压变质带中榴辉岩和其中的脉体形成过程中流体的盐度及其变化.仰口榴辉岩中磷灰石在进变质过程中显示为氯含量增加,反映出俯冲的大陆岩石经受了一个逐步干化和流体活动性降低的过程;在退变质过程中氯含量降低,反映超高压岩石折返过程中流体含量增加.大别-苏鲁超高压变质带一些典型的露头,包括池庄、青龙山、毛北、碧溪岭、毛屋、朱家冲和花凉亭等地的超高压榴辉岩及其中的脉体,其磷灰石成分变化很大,指示榴辉岩相变质和脉体形成过程中流体盐度变化很大,从低盐度流体到高盐度流体均存在,不同露头有所差异.总体来看,不同盐度的流体在变质过程中普遍存在,流体盐度的变化可能与大陆地壳俯冲/折返过程中岩石水化和脱水反应有关.
华北陆块古生代南向增生与秦岭-桐柏-红安造山带构造演化

秦岭-桐柏-红安造山带记录了华南与华北陆块在古生代时期的拼合过程,包含了华北陆块在这个时期的三阶段南向增生.秦岭群可能是Rodinia超大陆裂解过程中从华南陆块或相同构造属性陆块分离并向北漂移到华北克拉通南缘的微陆块.宽坪群和二郎坪群低级变质沉积岩原岩可能是华北克拉通南缘俯冲带之上的增生楔,在北秦岭微陆块北向俯冲过程中受到变质变形作用.北秦岭超高压变质岩石在寒武纪的形成可能代表了一次小陆块与大陆块之间的碰撞事件,结果导致北秦岭地体增生到华北克拉通南缘.秦岭群中的麻粒岩相变质作用与秦岭群广泛发育的深熔作用和岛弧岩浆作用准同时发生,可能代表了古特提斯洋壳俯冲、弧后盆地关闭及其导致的弧-陆碰撞事件,导致华北大陆第二次向南增生.石炭纪高压变质作用代表了古特提斯洋壳俯冲和第二次弧-陆碰撞事件,结果导致华北大陆第三次向南增生.华南陆块与华北陆块之间的最终拼合发生在三叠纪,在西部的秦岭-桐柏-红安造山带记录了增生型弧-陆碰撞过程,而在东部的大别-苏鲁造山带表现为两个古老大陆之间的直接碰撞.
新疆西南天山超高压变质带的空间分布、峰期变质时代和P-T轨迹特征

总结了近年来有关新疆西南天山超高压变质带研究取得的进展.根据新发现的柯石英矿物包体,结合以前报道的一些超高压变质矿物学证据,在西南天山蓝片岩-榴辉岩带中确定了长约80 km,宽10 km以上的超高压变质带,这是目前出露规模最大的洋壳岩石深俯冲超高压变质带,并确定了其由南向北的俯冲带极性.对含有柯石英的石榴石云母片岩中变质生长锆石边的定年,获得超高压变质时代为320±3.7 Ma,结合退变榴辉岩中获得的233-226 Ma变质边锆石的时代,确定了其退变过程经历了漫长的变质演化.根据详细的岩石学相平衡模拟计算,确定了西南天山含柯石英榴辉岩和石榴石多硅白云母片岩的P-T轨迹都具有热弛豫特征,即温度峰值期滞后于压力的峰值期,表明超高压变质岩石在俯冲通道中经历了缓慢的、长时间的升温减压抬升过程.根据少量的榴辉岩透镜体包裹于大面积的云母片岩中的野外产状特征,而且含柯石英榴辉岩和云母片岩都具有相似的P-T轨迹,提出了西南天山超高压变质榴辉岩的抬升可能是由于大面积的低密度的云母片岩抬升折返过程中把密度较大的榴辉岩携带到地表的新认识.
诱导多能干细胞在脊髓与周围神经疾病中的研究进展与前景

诱导多能干细胞(induced pluripotent stem cells, iPS 细胞)技术是干细胞领域的一门新兴技术,是通过向体细胞中导入特定转录因子,从而诱导体细胞重编程获得未分化的多能细胞的技术,通过这种技术获得的多能细胞有与胚胎干细胞类似的性能和多向分化能力。该技术在2008年被Science杂志评为十大科学突破之首。
突发性耳聋高压氧治疗时机的选择与疗效

目的:探讨突发性耳聋患者高压氧治疗时机与疗效的关系。方法:对236例突发性耳聋患者进行高压氧综合治疗,并分析高压氧疗效与高压氧介入时间及治疗次数的关系,探讨本文高压氧介入时间超过15d的患者未及时行高压氧治疗的原因。结果:本文236例患者经过高压氧综合治疗,痊愈118例(50%),有效198例(83.9%)。高压氧介入时间1-14d总有效率91.54%,痊愈率59.23%,15d以上总有效率74.53%,痊愈率38.68%,两组总有效率与痊愈率比较均有显著性差异(P<0.05),患者痊愈与有效需要的治疗次数明显少于超过15d的患者,说明高压氧早期介入有效率高且需要的治疗次数少。结论:高压氧综合治疗的早期介入且坚持足够疗程的治疗具有较好的疗效。
婴幼儿颈胸部巨大血管瘤一例

血管瘤是婴幼儿最常见的软组织良性肿瘤,发病率为3%-8%,男女患病比为1:3至1:5,多见于头面部、胸背部及四肢。根据Mulliken-Glowacki等生物学分类方法分为真性血管瘤和血管畸形两大类,内皮细胞增殖活跃者为真性血管瘤,内皮细胞增殖相对稳定者为血管畸形。真性血管瘤又分为表浅性毛细血管瘤、深部性海绵状血管瘤、混合性毛细血管海绵状血管瘤。真性血管瘤绝大多数可自行消退,部分不能自然消退者,手术切除是最有效的治疗方法,尤其是头颈部、血管瘤迅速增大者,更应及早手术治疗。现报告1例婴幼儿颈胸部巨大毛细血管瘤的诊治体会。
联合应用颏下翻转皮瓣和腹部游离皮片修复咽瘘1例

咽瘘是指唾液潴留于皮下或切口下组织,形成脓腔致皮肤破溃,造成喉咽、食管腔等与皮肤相通而形成的窦道,其发生率在3.2%~38.6%之间。现报道1例利用颏下翻转皮瓣联合腹部游离皮片修复咽瘘。
解读“美国感染性疾病学会儿童和成人急性细菌性鼻及鼻窦炎临床指南”

2012-03-20美国感染性疾病学会在官方网站http://cid.oxfo rdjournals.org发表了儿童和成人急性细菌性鼻及鼻窦炎临床指南。该指南由多学科专家(包括临床和实验学专家、急诊医学专家、耳鼻咽喉科专家、公共健康专家、流行病专家、成人和儿童感染疾病专家)在收集分析相关文献的基础上,对数据类型和推荐等级分别进行了分类和分级,充分反映了所依赖数据的可靠程度。指南重点突出临床实用性,主要针对社区全科医师、家庭医师、实习医师、儿科医师、急诊医师和变态反应科医师。
结直肠癌肝转移转化治疗中靶向药物合理应用的专家指导意见

肝转移灶完整切除是结直肠癌肝转移获得潜在治愈的唯一机会。转化治疗对提高结直肠癌肝转移患者手术切除率,延长生存时间和改善预后具有重要意义。转化治疗的目标应该是尽量应用具有最高效率的治疗方案,以期获得尽可能高的转化切除率。为进一步规范靶向药物在结直肠癌肝转移转化治疗的合理应用,中国抗癌协会大肠癌专业委员会组织肝脏外科、结直肠外科和消化道肿瘤内科专家,结合该领域国内外最新进展,提出结直肠癌肝转移转化治疗中靶向药物合理应用的专家指导意见,旨在为我国外科医生的临床实践提供参考。
医学微生物学双语教学的思考与探索

双语教学是我国高等院校教育改革的一项重要内容,为适应我国社会高速发展对人才的更高要求,提高学生自身专业外语水平,本文阐述了医学院校开展医学微生物学双语教学的重要性和必要性,总结了双语教学的英文教材,教学课件与授课方法,初步探讨了医学微生物学双语教学模式,从而使医学院校学生达到既学习本专业基础知识又提高英语水平的目的。
腰椎后路固定Cage椎体间融合术在老年复杂型腰椎管狭窄症的近期疗效观察

[目的]评估后路减压并椎体间融合及内固定治疗老年复杂型腰椎管狭窄症的临床疗效。[方法]回顾性分析2006年1月~2011年1月采用后路减压、植骨融合、椎弓根螺钉系统内固定治疗复杂性腰椎管狭窄症患者43例,男29例,女14例;平均年龄64.5岁。病史2~25年。合并退变性Ⅰ度以上滑脱21例,合并腰椎侧凸、Cobb角>20°12例。术中对一个或两个节段者切除椎间盘,处理相邻椎板,行椎间植骨融合。[结果]根据JOA评分标准,优良率88.3%,末次随访X线片观察:滑脱复位率96%,腰椎侧凸者Cobb角平均6.6°,矫正率88.5%,融合率91.3%。[结论]后路减压固定并椎体间融合是治疗老年复杂型腰椎管狭窄症的有效方法。
胸椎管内髓外硬膜下骨肉瘤影像表现一例

椎管内髓外硬膜下骨肉瘤应首选手术治疗,旨在切除肿瘤,解除肿瘤对脊髓的压迫,术后应辅助放疗。本例MRI虽然未能作出正确诊断,但是对早期检测出肿瘤、术中定位以及术后随访有重要价值。
柴胡桂枝干姜汤加减治疗慢性羊水过多40例

目的观察柴胡桂枝干姜汤加减治疗慢性羊水过多的临床疗效。方法将慢性羊水过多患者70例随机分为治疗组40例和对照组30例。对照组适当低盐饮食,控制饮水量;治疗组在对照组基础上给予柴胡桂枝干姜汤加减,每日1剂,治疗7天。观察两组临床疗效,并观察治疗前后羊水指数(AFI)变化及临床体征改善情况,同时于治疗后检测胎儿动脉导管狭窄情况。结果治疗组临床疗效总有效率为82.50%,对照组为36.66%,两组比较差异有统计学意义(P<0.01);治疗组患者治疗后AFI明显低于治疗前(P<0.05),两组治疗后AFI比较差异有统计学意义(P<0.05);两组治疗后各临床体征与治疗前比较均明显改善(P<0.01),治疗组治疗后各临床体征改善情况明显优于对照组(P<0.01)。结论柴胡桂枝干姜汤加减能改善慢性羊水过多患者临床体征,降低AFI。
调补宗气治疗冠心病的思路

中医治疗冠心病的主要方法是活血化瘀、泄浊豁痰、温阳益气、益气养阴等,其中活血化瘀法被广泛运用。本文认为,宗气不足,无力推动营血运行则血脉瘀滞,气血不通,而心胸憋闷疼痛;又因无以行呼吸而"喘息咳唾,短气",从而发为"胸痹之病,喘息咳唾,胸背痛,短气"。因而,开宣肺气和补益脾气,从而调补宗气是治疗冠心病的重要方法。
慢性炎症与肺癌发病关系的研究进展

目前,肺癌的发病率占所有肿瘤的首位,其5年生存率不足15%,文献报道,细菌性肺炎、肺结核或炎症性肺疾病患者发生肺癌的风险明显增加,提示肺癌的发病与肺部慢性炎症有关。
Characteristics of biomarkers in source rocks of the Ganquan Formation in the Dahulishan region, Ejina Banner

Based on gas chromatography and gas chromatography mass spectrometry techniques, the authors examined biomarker characteristics of the Ganquan Formation source rocks in the area of Dahulishan, Ejina, and analyzed the information and petroleum geological significance that were indicated by the source of organic matter, sedimentary environment and maturity and so on. Gas chromatography peak of saturated hydrocarbons from the Ganquan Formation source rocks showed "the former peak" of the single peak distribution, the main peak of carbon being C_(18), indicating the main sources of organic matter with marine organic matter. Pr/Ph ranges from 0.3 to 0.6, indicating a strongly reducing sedimentary environment. Biomarker assemblages of the Ganquan Formation source rocks are abundant in tricyclic terpane with long side chains, with a high level of gammacerane, showing dominant distribution of C_(27) sterane. High contents of gammacerane in organic matter show organic facies of source rocks in the saltwater sedimentary environment. That average hopane/sterane ratio is 0.59, showing that algae have made more contributions to organic matter than bacteria. And the high level of C_(27) steranes shows that algae are the main source of hydrocarbon precursors. The Ganquan Formation’s methylphenanthrene index, which is an effective molecular parameter index to measure thermal evolution of organic matter, ranges from 0.35 to 0.50, and the conversion of vitrinite reflectance Rc from it is within the range of 2.00-2.09, indicating that the Ganquan Formation source rocks are in the over-mature stage of thermal evolution.
Uptake, accumulation and translocation of polycyclic aromatic hydrocarbons by winter wheat cultured on oily sludge-amended soil

The purpose of this study is to comparatively investigate the plant uptake, accumulation and translocation behaviors of polycyclic aromatic hydrocarbons (PAHs) as priority pollutants in soil contaminated with oily sludge. The influence of different oily sludge application doses on the uptake of contaminants was studied together with the profile of individual PAH in roots, straws and leaves of winter wheat. Pot experiments were conducted using oily sludge application doses of 0, 5, 10, 15 and 20 percent, respectively. The total PAHs contents of control soil and oily sludge were 16.96 and 3504.66 μg/g, respectively. Analysis for the contents of the 16 PAHs was carried out with a HPLC-UV using plant tissue samples obtained at the 265~(th) day of growth. The total PAHs contents in treated winter wheat were 9.02-334.81 ng/g for roots, 8.45-336.52 ng/g for straws and 10.70-406.32 ng/g for leaves. In addition to 5% of oily sludge dose, the total PAHs content in leaves was always highest under other doses of oily sludge application. With respect to individual PAH, the content did not show a significant plant tissue related trend. However, both the total content and individual content of PAHs in treated winter wheat tissues did increase with increasing oily sludge application dose. Another analysis for the control soil indicates that the degradation rate of PAHs was significantly enhanced by winter wheat after 265 days of growth based on the residual concentrations of PAHs in planted and unplanted soils.