mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
放射性核素示踪技术在心脏干细胞移植中的应用

将干细胞移植至受损心脏替代坏死心肌，修复心肌结构和功能，以治疗心肌梗死，近年来取得了令人鼓舞的成果~([1])，但仍然存在很多待解决问题，核心问题是移植干细胞在宿主体内的去向和命运~([2])。通过处死动物后利用心脏组织切片进行定性和半定量分析与临床应用要求相去甚远。放射性核素干细胞活体示踪技术可以对干细胞在体的分布、归巢、增殖情况进行监测，从而有助于了解干细胞治疗的机制和协助治疗策略的选择。笔者就目前放射性核素干细胞活体示踪技术在心脏干细胞移植方面的应用情况作一综述
Design and Performance of a Novel Pancake Rogowski Coil for Measuring Pulse Currents

A novel pancake Rogowski coil without magnetic core is introduced in this paper. Owing to its special pancake winding structure, the coil is of low self-resistance and high self- inductance, and thus has excellent low frequency characteristic in the self-integral mode. Moreover, because of its unique installation method, the coil has a flexible sensitivity and can be applied under situations where toroidal air-core Rogowski coils or printed aircuit board (PCB) coils are not available. The parameters and performance of the pancake Rogowski coil are presented, and the principle of shielding is given. Measurements of step pulse current and oscillating pulse current by the coil are studied experimentally to illustrate its good linearity, reliable and flexible sensitivity and excellent frequency characteristic, especially its advantage in low frequency characteristic. The pancake Rogowski coil can be designed to assume round, square or rectangle shape, and has thus broad prospects in its application to the current measurement in such areas as plasma physics and pulsed power technology.
Experimental study of destruction to porcine spleen in vivo by microwave ablation

AIM: To discuss the safety, feasibility and regularity of destruction to porcine spleen in vivo with congestion and tumescence by microwave ablation (MWA). METHODS: Ligation of the splenic vein was used to induce congestion and tumescence in vivo in five porcine spleens, and microwave ablation was performed 2-4 h later. A total of 56 ablation points were ablated and the ablation powers were 30-100 W. The ablation time (1, 2, 3, 4, 5, 6, 7, 8, 9 and 10 min) was performed at a power of 60 W. After ablation, the ablation size was measured in pigs A, C, D and E and spleen resection. In pig B, the ablation size was measured and 2 ablation points were sent for pathology analysis and all tissues were sutured following ablation. Pig B was killed 1 wk later and the ablation points were sent for pathology analysis. Bleeding, tissue carbonization surrounding electrodes, and pathological changes were observed, and the effect on destruction volume relative to different ablation powers, times and positions was analyzed. RESULTS: The incidence of bleeding (only small amounts, < 20 mL) in the course of ablation was 5.4% (3/56) and was attributed to tissue carbonization surrounding electrodes, which also exhibited an incidence of 5.4% (3/56). The destruction volume was influenced by different ablation powers, times and points. It showed that the ablation lesion size increased with increased ablation time, from 1 to 10 min, when the ablation power was 60 W. Also, the ablation lesion size increased with the increase of ablation power, ranging from 30 to 100 W when the ablation time was set to 3 min. A direct correlation was seen between the destruction volume and ablation time by the power of 60 W (r = 0.97542, P < 0.0001, and also between the destruction volume and ablation powers at an ablation time of 3 min (r = 0.98258, P < 0.0001). The destruction volume of zone II (the extra-2/3 part of the spleen, relative to the first or second class vascular branches), which was near the hilum of the spleen, was noteably larger than the destruction volume of zone I (the intra-1/3 part of the spleen) which was distal from the hilum of the spleen (P = 0.0015). Pathological changes of ablation occurring immediately and 1 wk after MWA showed large areas of coagulation. Immediately following ablation, intact spleen tissues were observed in the areas of coagulation necrosis, mainly around arterioles, and there were no obvious signs of hydropsia and inflammation, while 1 wk following the ablation, the coagulation necrosis was well distributed and complete, as many nuclear fragmentations were detected, and there were obvious signs of hydropsia and inflammation. CONCLUSION: In vivo treatment of congestion and tumescence in the spleen using microwave ablation of water-cooled antenna is a safe and feasible method that is minimally invasive.
体外受精-胚胎移植中两种给药方案垂体降调节临床结局分析

目的探讨体外受精-胚胎移植(IVF-ET)中两种给药方案垂体降调节对临床结局的影响。方法对2010年3-10月于福建省妇幼保健院接受IVF-ET助孕治疗、采用促性腺激素释放激素激动剂(GnRH-a)黄体期长方案超排卵的患者239例243个周期的资料进行回顾性分析。根据不同的GnRH-a给药方案分为两组：A组[曲普瑞林（达必佳）连续小剂量0.05mg,1次、d]131个周期；B组[曲普瑞林（达菲林）单剂量1.0~1.2mg]112个周期。结果B组方案降调节对垂体的抑制更深，致促性腺激素(Gn)使用时间更长，Gn量更大(P<0.05)。两组获卵数、受精率、卵裂率、优质胚胎率、临床妊娠率、种植率、卵巢过度刺激综合征(OHSS)发生率、流产率、异位妊娠率比较差异均无统计学意义(P>0.05)。结论达必佳连续小剂量0.05mg(1次/d)与达菲林单剂量1.0~1.2mg均可获得满意的垂体降调节效果和IVF结局；两种给药方案的应用各有利弊。
细辛脑注射液致过敏反应2例

细辛脑注射液中含有丙二醇、聚山梨酯80等附加剂，也可能使患者发生过敏反应~([1])。因此，在进行静脉输液时，应仔细询问患者有无药物过敏史或过敏体质，是否使用其它药物，滴注开始速度宜慢，并仔细观察患者的反应，一旦出现过敏反应立即停用原输液并给予相应的对症处理，避免出现严重的后果，确保用药安全。
以胸腔积液为主要表现的肺黏液腺癌一例

总之，对于肺黏液腺癌仅根据影像学表现难以确诊，应尽早进行病理学诊断，以争取治疗时间。对于不明原因的胸腔积液患者，应尽早行胸腔镜检查。内科胸腔镜作为一种成熟安全的侵人性操作技术，既可清晰观察到壁层及脏层胸膜、膈肌以及胸腔内的形态学改变，又可选取最佳的部位取活检。对于该类疾病，取活检的部位尽可能选择病变早期纤维素未形成的部位，可明显提高检出率。
多囊卵巢综合征的诊治进展

早在1935年，Stein和Leventhal~([1])就发表了文章，对7例妇女同时存在闭经、多毛、肥胖以及卵巢上的多囊泡进行了描述，这是早期对多囊卵巢综合征(polycysticovarysyndrome,PCOS)的报道。多囊卵巢综合征的患病率在西方国家为4%~8%，但是由于诊断标准的不同，患病率也有很大的差别。据报道~([2])，在采用鹿特丹标准进行的某项社区研究显示，患病率可以高达18%，尤其需要引起关注的是，其中70%的患者之前未能得到诊断。在中国，有关多囊卵巢综合征的流行病学资料比较缺乏，近年来有增多趋势，发病率在各种报道中为3%~10%。多囊卵巢综合征以闭经、多毛、雄激素水平升高、不孕、肥胖及卵巢的多囊为主要表现，影响妇女的生殖系统、代谢系统和心血管系统的健康，在疾病的诊断、发病机制以及治疗上均比较复杂。本文对多囊卵巢综合征的发病机制、诊断要点以及治疗进行综述，希望可以提高对该病的认识。
Frugivory and seed dispersal in the Galapagos: what is the state of the art?

The Galapagos are considered a model oceanic archipelago, with unique flora and fauna currently threatened by alien invasive species. Seed dispersal is an important ecosystem function with consequences for plant population dynamics and vegetation structure. Hence, understanding the seed dispersal abilities of the assemblages of frugivores will inform scientists and managers of the dynamics of plant invasions and improve management planning. Here we provide the first comprehensive review of published information on frugivory and animal seed dispersal in the Galapagos. We collected data from a variety of sources, including notes of the first naturalist expeditions, gray literature available only in Galapagos collections, and peer-reviewed journal articles. Plant–animal frugivorous interactions were retrieved from 43 studies and compiled into an interaction matrix describing 366 unique interactions. Most studies focused on fruit consumption as a driving force for natural selection, but seed fate was seldom considered. Although most (71%) of the interactions involved native plants, more than one-quarter (28%) involved introduced species. Interactions involving birds are considerably more common than those of reptiles and mammals, probably reflecting a research bias towards birds. Despite the historical importance of the archipelago as the laboratory for evolutionary and ecological research, understanding of its seed dispersal systems is limited. We end the review by suggesting 3 priority areas of research on frugivory and seed dispersal in the Galapagos: (i) target research to close knowledge gaps; (ii) the use of a network approach to frame seed dispersal at the community level; and (iii) evaluation of the effect of seed dispersal as a selective pressure acting upon plants and frugivores. Finally, the output of this research has to be properly delivered to the Galapagos National Park Services to help increase management effectiveness.
Frugivory and seed dispersal: integrating patterns, mechanisms and consequences of a key animal–plant interaction

The study of frugivory and seed dispersal is both exciting and challenging because it integrates research from multiple biological disciplines, including zoology, botany, physiology, behavioral ecology, evolution, conservation, and population and community ecology. At the center of these investigations is one of the most important mutualistic relationships hypothesized to organize and maintain diversity in terrestrial ecosystems: the movement of plant seeds by fruit and seed-eating animals (Bascompte & Jordano 2007). Although recent studies on the seed dispersal process have advanced the breadth and depth of our understanding of this keystone interaction, many questions are still unanswered. A clear synthesis and theoretical framework for integrating what we do know also remains elusive. Moreover, the imperative to better understand the movement of organisms in the face of human-induced global changes has sparked an additional need for seed dispersal studies (Wang & Smith 2002; Bullock & Nathan 2008; Nathan et al. 2008). It might seem curious that research on seed dispersal commonly leads to the study of animals, but, indeed, the vast majority of woody plants are dispersed by frugivores and granivores (Herrera 2002). This special section of Integrative Zoology features eight papers in frugivory and seed dispersal, and it is a sequel to the special section published earlier this year (Campos-Arceiz et al. 2011). Here, we present a set of research articles that provide readers with both a taste of the wide spectrum of topics and approaches that this field entails, and a glimpse of the vast challenges involved in integrating and synthesizing the results from such a broad field of study.
Effect of microcystin-LR on protein phosphatase 2A and its function in human amniotic epithelial cells

Due to their toxicity, the increased distribution of microcystins (MCs) has become an important worldwide problem. MCs have been recognized as inhibitors of protein phosphatase 2A (PP2A) through their binding to the PP2A catalytic subunit. However, the exact mechanism of MC toxicity has not been elucidated, especially concerning the cellular response and its autoregulation. To further dissect the role of PP2A in MC-induced toxicity, the present study was undertaken to determine the response of PP2A in human amniotic epithelial (FL) cells treated with microcystin-LR (MCLR), one of the MC congeners. The results show that a low-dose treatment of MCLR in FL cells for 6 h induced an increase in PP2A activity, and a high-dose treatment of MCLR for 24 h decreased the activity of PP2A, as expected. The increased mRNA and protein levels of the PP2A C subunit may explain the increased activity of PP2A. Furthermore, MCLR altered microtubule post-translational modifications through PP2A. These results further clarify the underlying mechanism how MCLR affects PP2A and may be helpful for elucidating the complex toxicity of MCLR.
从毒邪角度探讨白塞病中医病因病机

白塞病以反复发作性口腔、生殖器溃疡,眼炎和皮肤损害为特征,属中医学“狐惑”范畴。一般认为,本病的病因病机与毒邪有关。如巢元方《诸病源候论》指出,本病“皆湿毒所为也”；吴谦《医宗金鉴》认为“每因伤寒病后余毒与淫之为害也”；近代岳美中言：“狐惑病是温毒热性病治疗不得法,邪毒无从发泄而自寻出路的转变重症。”笔者现从毒邪角度对其病因病机进行探讨。
穴位敷贴治疗咳嗽变异性哮喘疗效观察

咳嗽变异性哮喘(coughvariantasthma,CVA)又称为非典型哮喘、过敏性咳嗽、咳嗽型哮喘或隐匿型哮喘,主要表现为夜间或清晨咳嗽,一般无喘息、气促症状,但有气道高反应,吸入冷空气、尘螨、刺激性物质等容易诱发或加重。笔者运用中药穴位敷贴结合复方甲氧那明胶囊治疗该病,取得较好疗效,现报道如下。
中药内服与灌肠联合治疗湿热型溃疡性结肠炎36例

溃疡性结肠炎(ulcerativecolitis,UC)是一种主要累及直肠、结肠黏膜和黏膜下层的慢性非特异性肠道疾病,临床主要表现为腹痛、腹泻及黏液、脓血便等。近年来,随着生活水平的提高,饮食结构、生活习惯及环境的变化,其发病率逐年增高。笔者采用芍药汤内服结合中药灌肠治疗湿热型UC患者36例,取得较满意疗效,现报道如下。
THE TIME INTERVAL ALIGNMENT (IA) POLICIES, BOUNDARY AND APPLICATIONS WITH MULTIPLE STREAM ARRIVALS

This paper discusses a class of interval alignment (IA) scheduling policies, which are particularly effective for the systems that do not have Markovian structure. The numerical results show that IA policies effectively smooth part flows, improve performance and decrease average Work-in-Process (WIP) by adding intermediate delays to the system. The boundary of IA policy is proven and the applications of IA policy in the system with multiple stream arrivals have been discussed. With the combination of release policy, it is practical to implement IA to multiple stream arrival system.
A CASE STUDY FOR ADVANCED PLANNING AND SCHEDULING (APS)?

This paper presents a case study for the advanced planning and scheduling (APS) problem encountered in a light source manufacturer. The APS problem explicitly considers due dates of products, operation sequences among items, and capacity constraints of the manufacturing system. The objective of the problem is to seek the minimum cost of both production idle time and tardiness or earliness penalty of an order. An intelligent heuristic is applied to the problem, and the results demonstrate that significant production performances can be achieved while ensuring customer satisfaction as opposed to normal practices followed in the company relying on human expertise.
RE-ENGINEERING TRANSFORMER MAINTENANCE PROCESSES TO IMPROVE CUSTOMIZED SERVICE DELIVERY

The outage of a transformer in a power generation system will generally result in a shutdown of the entire system. Consequentially, large amounts of revenue are lost to the plant owner with a substantial negative impact on the civil community and industrial customers. This paper analyzes the current maintenance practices (i.e., an as-is process model) of a transformer manufacturing company, which provides maintenance services to power generation plants and reports the major weaknesses in current business practices. The maintenance weaknesses include isolated processes and paper based information communication. These inefficient processes result in service delays, cost increases, and inappropriate responses to customers’ specific requests and complaints. To improve the efficiency and flexibility of the entire transformer maintenance service system, an e-integration approach is implemented with three key tasks. First, the current business processes are re-engineered to provide an improved (to-be) business model. Then, we replace paper based documentation methods with an electronic filing system for efficient and cost-effective information exchange. Afterward, the improved process model is implemented as an Internet based system to enhance the interactions among the transformer manufacturer, end-users, and service contractors for customized maintenance services. The case study demonstrates that implementing the e-integration approach increases the efficiency and effectiveness of the customized maintenance services.
A NEUROENDOCRINE-INSPIRED BIONIC MANUFACTURING SYSTEM

Due to rapid changes of markets and pressures of competitions, the manufacturing companies are forced to adapt their production ways to support diversity of customer’s needs and increase of new product developments. As biological organisms are quite capable of adapting to environmental changes and stimulus, bio-inspired concepts have been recognized much suitable for adaptive manufacturing system control. This paper, therefore, proposes a novel concept of NeuroEndocrine-Inspired Manufacturing System (NEIMS). The proposed NEIMS control architecture is based on analogies with neuro-control and hormone-regulation principles. It has the capability to explicitly specify production control schemes including control points, material, information flow paths and logical operations, and to agilely deal with the frequent occurrence of unexpected disturbances at the shop floor level. From the cybernetics point of view, the control model of NEIMS indicates adaptive behavior to the changes in products demands due to external environment and malfunction of manufacturing cells as an internal environment. Finally, a prototype system has been set up to enable the NEIMS simulation.
A DESIGN FOR ENVIRONMENT METHODOLOGY FOR EVALUATION AND IMPROVEMENT OF DERIVATIVE CONSUMER ELECTRONIC PRODUCT DEVELOPMENT

Increasing environmental awareness and stringent environmental regulations have motivated many companies to incorporate ecodesign into product development. To assist companies to address the challenge, this research presents a design for environment (DfE) methodology to evaluate and improve derivative consumer electronic product development using a back-propagation neural network (BPNN) model and a technique for order preference by similarity to ideal solution (TOPSIS) method. Based on use of a BPNN, the life cycle assessment (LCA) models are developed to estimate quantities of hazardous chemical substances and energy consumption for a derivative consumer electronic product throughout the product life cycle. A performance evaluation and improvement model for DfE is then devised based on the TOPSIS method to analyze the ecodesign performance and provide concrete improvement strategies. With the aforementioned analysis of environmental performance, an enterprise can profoundly understand and significantly enhance the relative DfE performance of a new product compared to the similar competitive products. Finally, we apply an optical mouse development project as a case to elaborate and demonstrate the effectiveness of the proposed methodology. These analytical results can let us understand the DfE performance ranking and acquire the maximum reduced quantity of each DfE criterion for each module of a new product. Meanwhile, to enhance the green competitiveness of the new product, we recommend that the engineers should decrease the area of the circuit board of the new product. In addition, the material of the USB cable for the new product should be switched from the PVC material to the PE material.
Aerodynamic modeling and stability analysis of a high-speed train under strong rain and crosswind conditions

With the development of high-speed train, it is considerably concerned about the aerodynamic characteristics and operation safety issues of the high-speed train under extreme weather conditions. The aerodynamic performance of a high-speed train under heavy rain and strong crosswind conditions are modeled using the Eulerian two-phase model in this paper. The impact of heavy rainfall on train aerodynamics is investigated, coupling heavy rain and a strong crosswind. Results show that the lift force, side force, and rolling moment of the train increase significantly with wind speed up to 40 m/s under a rainfall rate of 60 mm/h. when considering the rain and wind conditions. The increases of the lift force, side force, and rolling moment may deteriorate the train operating safety and cause the train to overturn. A quasi-static stability analysis based on the moment balance is used to determine the limit safety speed of a train under different rain and wind levels. The results can provide a frame of reference for the train safe operation under strong rain and crosswind conditions.
A cryogenic SAR ADC for infrared readout circuits

A cryogenic successive approximation register(SAR) analog to digital converter(ADC) is presented. It has been designed to operate in cryogenic infrared readout systems as they are cooled from room temperature to their final cryogenic operation temperature.In order to preserve the circuit’s performance over this wide temperature range, a temperature-compensated time-based comparator architecture is used in the ADC, which provides a steady performance with ultra low power for extreme temperature(from room temperature down to 77 K) operation.The converter implemented in a standard 0.35μm CMOS process exhibits 0.64 LSB maximum differential nonlinearity (DNL) and 0.59 LSB maximum integral nonlinearity(INL).It achieves 9.3 bit effective number of bits(ENOB) with 200 kS/s sampling rate at 77 K, dissipating 0.23 mW under 3.3 V supply voltage and occupies 0.8×0.3 mm~2.
A passive UHF RFID tag chip with a dual-resolution temperature sensor in a 0.18μm standard CMOS process

This paper presents a passive EPC Gen-2 UHF RFID tag chip with a dual-resolution temperature sensor. The chip tag integrates a temperature sensor, an RF/analog front-end circuit, an NVM memory and a digital baseband in a standard CMOS process.The sensor with a low power sigma-delta(ΣΔ) ADC is designed to operate in low and high resolution modes.It can not only achieve the target accuracy but also reduce the power consumption and the sensing time.A CMOS-only RF rectifier and a single-poly non-volatile memory(NVM) are designed to realize a low cost tag chip.The 192-bit-N VM tag chip with an area of 1 mm~2 is implemented in a 0.18-μm standard CMOS process.The sensitivity of the tag is -10.7 dBm/-8.4 dBm when the sensor is disabled/enabled.It achieves a maximum reading/sensing distance of 4 m/3.1 m at 2 W EIRP.The inaccuracy of the sensor is -0.6℃/0.5℃(-1.0℃/1.2℃) in the operating range from 5 to 15℃in high resolution mode(-30 to 50℃in low resolution mode).The resolution of the sensor achieves 0.02℃(0.18℃) in high(low) resolution mode.
Design of 700 V triple RESURF nLDMOS with low on-resistance

A 700 V triple RESURF nLDMOS with a low specific on-resistance of 100 mΩ·cm~2 is designed.Compared with a conventional double RESURF nLDMOS whose P-type layer is located on the surface of the drift region, the P-type layer of a triple RESURF nLDMOS is located within it.The difference between the locations of the P-type layer means that a triple RESURF nLDMOS has about a 30%lower specific on-resistance at the same given breakdown voltage of 700 V.Detailed research of the influences of various parameters on breakdown voltage, specific on-resistance, as well as process tolerance is involved.The results may provide guiding principles for the design of triple RESURF nLDMOS.
AlGaAs/GaAs tunnel junctions in a 4-J tandem solar cell

TheⅢ-Ⅴcompound tandem solar cell is a third-generation new style solar cell with ultra-high efficiency. The energy band gaps of the sub-cells in a GaInP/GaAs/InGaAs/Ge 4-J tandem solar cell are 1.8, 1.4, 1.0 and 0.7 eV, respectively.In order to match the currents between sub-cells, tunnel junctions are used to connect the sub-cells.The characteristics of the tunnel junction, the material used in the tunnel junction, the compensation of the tunnel junction to the overall cell’s characteristics, the tunnel junction’s influence on the current density of sub-cells and the efficiency increase are discussed in the paper.An AlGaAs/GaAs tunnel junction is selected to simulate the cell’s overall characteristics by PC1D, current densities of 16.02, 17.12, 17.75 and 17.45 mA/cm2 are observed, with a Voc of 3.246 V, the energy conversion efficiency under AM0 is 33.9%.
Optimization of Al_2O_3/SiN_x stacked antireflection structures for N-type surface-passivated crystalline silicon solar cells

In the case of N-type solar cells, the anti-reflection property, as one of the important factors to further improve the energy-conversion efficiency, has been optimized using a stacked Al_2O_3/SiN_x layer.The effect of SiN_x layer thickness on the surface reflection property was systematically studied in terms of both experimental and theoretical measurement.In the stacked Al_2O_3/SiN_x layers, results demonstrated that the surface reflection property can be effectively optimized by adding a SiN_x layer, leading to the improvement in the final photovoltaic characteristic of the N-type solar cells.
Pb(Zr_(0.52)Ti_(0.48))O_3 memory capacitor on Si with a polycrystalline silicon/SiO_2 stacked buffer layer

Pb(Zr_(0.52)Ti_(0.48))O_3（PZT） thin films have been deposited on a p-type Si substrate separated by a polycrystalline silicon/SiO_2 stacked buffer layer.The X-ray diffraction peaks of the PZT thin films prepared on the polycrystalline silicon annealed at different temperatures were measured.In addition, the polarization of the Pt/PZT/polycrystalline silicon capacitor has been investigated.The memory capacitor of the metal/ferroelectric/polycrystalline silicon/SiO_2/semiconductor structure annealed at 650℃exhibits a clockwise capacitance-voltage hysteresis loop due to the ferroelectric polarization of the PZT thin film.The memory window increases with increasing the area coupling ratio between the SiO_2 capacitor and the PZT capacitor.