mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Metal-air batteries: A review on current status and future applications

Metal-air batteries (MABs) have been paid much more attention owing to their greater energy density than the most advanced lithium-ion batteries (LIBs). Rechargeable MABs are considered as promising candidates for the next-generation of energy storage techniques for applications ranging from large-scale energy storage systems to electric vehicles and portable devices. However, there are still numerous scientific problems that must be overcome before their commercial application. With the aim of providing a comprehensive understanding of this new electrochemical system particularly Li-air batteries, this review paper provides an overview of the current status including corresponding strategies from the perspective of various battery components, including air cathode,metal anode and electrolyte. In addition, other promising MABs such as Zn-air, Mg-air and Al-air batteries are also introduced briefly for comparison. Finally, the applications and prospects of these four types of MABs are discussed and some perspectives for this research field are also provided.
Global prevalence of drug-resistant tuberculosis: a systematic review and meta-analysis

Background Tuberculosis is a bacterial infectious disease, which affects different parts of a human body, mainly lungs and can lead to the patient's death. The aim of this study is to investigate the global prevalence of drug-resist-ant tuberculosis using a systematic review and meta-analysis. Methods In this study, the PubMed, Scopus, Web of Science, Embase, ScienceDirect and Google Scholar repositories were systematically searched to find studies reporting the global prevalence of drug-resistant tuberculosis. The search did not entail a lower time limit, and articles published up until August 2022 were considered. Random effects model was used to perform the analysis. The heterogeneity of the studies was examined with the I~2 test. Data analysis was conducted within the Comprehensive Meta-Analysis software. Results In the review of 148 studies with a sample size of 318,430 people, the I~2 index showed high heterogeneity (I~2=99.6), and accordingly random effects method was used to analyze the results. Publication bias was also examined using the Begg and Mazumdar correlation test which indicated the existence of publication bias in the studies(P=0.008). According to our meta-analysis, the global pooled prevalence of multi-drug resistant TB is 11.6% (95% CI: 9.1-14.5%). Conclusions The global prevalence of drug-resistant tuberculosis was found to be very high, thus health authorities should consider ways to control and manage the disease to prevent a wider spread of tuberculosis and potentially subsequent deaths.
Inflammation and cancer:paradoxical roles in tumorigenesis and implications in immunotherapies

Chronic inflammation caused by persistent infections and metabolic disorders is thought to contribute to the increased cancer risk and the accelerated cancer progression.Oppositely,acute inflammation induced by bacteria-based vaccines or that is occurring after cancer selectively inhibits cancer progression and metastasis.However,the interaction between inflammation and cancer may be more complex than the current explanations for the relationship between chronic and acute inflammation and cancer.In this review,we described the impact of inflammation on cancer on the basis of three perspectives,including inflammation with different durations (chronic and acute inflammation),different scopes (systemic and local inflammation) and different occurrence sequences (inflammation occurring after and before cancer).In addition,we also introduced bacteria/virus-based cancer immunotherapies.We perceive that inflammation may be a double-edged sword with cancer-promoting and cancer-suppressing functions in certain cases.We expect to further improve the understanding of the relationship between inflammation and cancer and provide a theoretical basis for further research on their complex interaction.
Transcriptomic analysis identifies a pan-cancer association of IL27 expression with cancer prognosis and immune microenvironment

Nowadays great progress has been made in targeted therapy and comprehensive therapy for a few cancers. But the prognosis of the vast majority of cancer patients is still weakness. It has been proven that inflammation can affect the development and treatment of cancer. Some previous studies have suggested that inflammation-related interleukins (ILs) play a significant role in the development of some cancers.1,2 ILs act as a considerable role in immunity,3 and inflammation affects the development of cancer. Therefore, the expression profile of IL gene may also be one of the vital markers of early pathological changes, occurrence and progression of cancer.4,5 Currently, studies on the expression of IL27 in cancer are still extremely limited. Our work comprehensively and systematically studied the IL27 gene expression in the generic cancer when compared with the existing IL27 gene related research experiment. We screened out cancer species linked with poor prognosis, and explored the correlation between IL27 gene expression and immune cell infiltration and immune microenvironment in these cancers further, providing an increasing number of the direct basis for subsequent studies. Our findings showed that IL27 can be used to assess prognosis and immune infiltration in patients with colon adenocarcinoma (COAD), glioblastoma multiforme (GBM), head and neck squamous cell carcinoma (HNSC), skin cutaneous melanoma (SKCM) and testicular germ cell tumors (TGCT) as a biomarker.
On some aspects of a bivariate alternative zero-inflated logarithmic series distribution

In this paper, we discuss some important aspects of the bivariate alternative zero-inflated logarithmic series distribution (BAZILSD) of which the marginals are the alternative zero-inflated logarithmic series distributions of Kumar and Riyaz (2015. An alternative version of zero-inflated logarithmic series distribution and some of its applications. Journal of Statistical Computation and Simulation, 85(6), 1117-1127). We study some important properties of the distribution by deriving expressions for its probability mass function, factorial moments, conditional probability generating functions, and recursion formulae for its probabilities, raw moments and factorial moments. The parameters of the BAZILSD are estimated by the method of maximum likelihood and certain test procedures are also considered. Further certain real-life data applications are cited for illustrating the usefulness of the model. A simulation study is conducted for assessing the performance of the maximum likelihood estimators of the parameters of the BAZILSD.
超时间窗串联血管病变血管内治疗1例

串联病变是急性大血管闭塞性卒中患者在其闭塞动脉近端存在重度狭窄或闭塞的动脉。串联病变的发生率高,较孤立动脉闭塞有着更差的预后。现报道一例患有串联病变,在发病3 d后血管内治疗成功血管开通的病例。患者为56岁男性,主因“一过性言语不清4 d再发3 d,右侧肢体无力1 d,加重13 h”急诊就诊,美国国立卫生院卒中量表(NIHSS)评分13分。全脑血管造影示左侧颈内动脉、大脑中动脉闭塞,行血管内治疗后成功血管开通。在术后3个月随访中,患者改良Rankin量表(mRS评分)为3分。
基于络病学说探讨良性前列腺增生症的病机及治疗

良性前列腺增生症(benign prostatic hyperplasia, BPH)是中老年男性最常见的以排尿障碍为主的慢性疾病,其中超过50%的患者会出现不同程度的下尿路症状(LUTS)。据一项基于1989-2014年间国内公开数据的荟萃分析显示,我国40 ~ 、50 ~ 、60 ~ 、70 ~和80岁以上男性BPH的发生率分别为2.9% 、29.0% 、 44.7% 、58.1%和69.2%,城市和农村地区BPH总发生率分别为41.5%和38.6% 。当前我国已进入老龄化社会,老龄人口基数大且增长迅速,BPH在未来的患病基数必将显著上升,同时也会成为影响老年男性生活质量的重要因素。因此,如何延缓疾病进程、改善患者LUTS、减少并发症、提高患者生活质量是当前泌尿外科医生的重点所在。在祖国传统医学中,医家们依据其病位在精室,症状多为小便无力或点滴而出,故将其归属于"精癃"的范畴。近年来,笔者对BPH的中医药治疗进行了相关研究,结合"络病学说"以及自身临床经验,认为"瘀"在BPH的发病过程中起着关键作用,化瘀通络法在BPH的治疗中疗效显著。故本文将基于络病学说刍议BPH的病机及治疗,并附验案一则以冀同道。
胸主动脉腔内隔绝术后脊髓缺血的病因及防治研究进展

自1994年Dake等应用腔内支架成功治疗胸降主动脉瘤以来,胸主动脉腔内隔绝术(thoracic endovascular aortic repair,TEVAR)彻底改变胸主动脉疾病的治疗方式,现TEVAR主要用于治疗胸主动脉瘤、胸主动脉夹层和胸主动脉损伤、胸主动脉壁内血肿、穿透性溃疡等。与开放修复相比, TEVAR不仅降低围手术期并发症发生率和病死率,而且远期疗效相似,因此成为首选治疗方式。然而,无论开放修复还是TEVAR,术后都可能发生脊髓缺血(spinal cord ischemia,SCI)。Scali等报道TEVAR术后SCI发生率为3.7%(422/11 473)。SCI使患者出现短暂性或永久性截瘫,甚至死亡,影响患者生活质量和长期生存率,是TEVAR术后严重并发症。本文对TEVAR术后SCI的发病机制及防治研究进展进行综述。
光学相干断层扫描技术在呼吸系统疾病中的研究与应用进展

呼吸系统疾病的诊疗与随访高度依赖于影像学、生理功能测试和组织病理等,其各有优劣,综合分析可显著提高呼吸系统疾病的诊疗水平。但临床上鲜有某种诊疗技术可以兼具影像学、生理功能测试和组织病理特点。寻找简单、高效、安全的诊疗措施,一直都是医学界的研究方向。光学相关断层扫描(optical coherence tomography,OCT)的出现为呼吸系统疾病诊疗技术的提升带来了曙光。
Influence of Limestone Addition on Combustion and Emission Characteristics of Coal Slime in the 75 t/h CFB Boiler with Post-Combustion Chamber

Coal slime can be disposed in quantity and fully utilized in a well-designed circulating fluidized bed (CFB) boiler, but the nitrogen oxides (NO_x) and sulphur dioxide (SO2) emissions generated in the combustion of coal slime have contributed to serious atmospheric pollution. High Temperature & Post-combustion Technology, a novel and high-efficient way to reduce the NO_x emission in the process of combustion, is applied to a 75 t/h CFB boiler burning exclusively coal slime, which will succeed to meet the ultra-low NO_x emission standard. To further explore an appropriate method to reduce the SO_2emission under the condition of new technology, the experiments were conducted on a 75 t/h CFB boiler with post-combustion chamber to study the influence of limestone addition on the combustion and emission characteristics of coal slime. The experimental results showed that High Temperature & Post-combustion Technology combined with the sorbent injection in the furnace is a very promising technology to control the NO_x and SO_2emissions simultaneously. Limestone addition can cause the slight decrease in combustion temperature. Limestone addition will lead to the increase in NO_x emission in the combustion of coal slime. In 75 t/h coal slime CFB boiler, the desulfurization efficiency of limestone injection in furnace is close to 98%, achieving the ultra-low SO_2emission. To meet the standard of ultra-low NO_x and SO_2emission, the two technologies for simultaneous removal of NO_x and SO_2emissions are economical and feasible currently: Removal of SO_2under ultra-low NO_x emission and Removal of NO_x under ultra-low SO_2emission.
Acute myocardial infarction following 5-fluorouracil treatment

5-Fluorouracil (5-FU) is an antimetabolite chemotherapeutic agent that is US Food and Drug Administration (FDA) indicated for use in a variety of neoplasms and is a staple agent in many chemotherapeutic regimens. An important adverse effect of 5-FU is cardiotoxicity. There is a wide spectrum of clinical presentation of 5-FU cardiotoxicity from asymptomatic electrocardiogram (ECG) changes to myocardial infarction that clinicians must be aware of when caring for patients receiving this agent.
Organic matter accumulation in lacustrine shale of the Permian Jimsar Sag, Junggar Basin, NW China

The lacustrine organic-rich shale in the Permian Lucaogou (LCG)Formation of the Jimsar Sag, Junggar Basin, is one of the main shale oil plays in China. In this paper, geological and geochemical research techniques were employed to evaluate the geochemical variability of the lacustrine shale and the production of organic matter and its preservation conditions. The LCG Formation is characterized by its complex mineral compositions and a wide range of organic matter richness and quality. The presence of high proportions of b-carotane and C29 steranes, indicates that the organic matter mainly originated from phytoplankton and aquatic algal-bacterial organisms, especially cyanobacteria. This study found that the productivity of the Lower LCG Member (P_2l_1)was highest, and the Middle LCG Member (P_2l_2)was the lowest. During the deposition of the Lower LCG Member, the lake's bottom water was predominantly a reducing environment, and the degradation of organic matter was largely a result of bacterial sulfate reduction. During the deposition of the Middle and Upper LCG members, the lake's bottom water was mainly oxidizing, and the degradation of organic matter was likely to be caused by aerobic processes. Based on a comprehensive analysis of the origin and production of organic matter, as well as its depositional environment and preservation conditions, two organic matter accumulation models were proposed to explain the distribution of the organic-rich shale. In model A, the high influx of volcanic ash released nutrients and brought abundant sulfate into the water, the accumulation of organic matter was mainly controlled by the preservation of organic matter, which was mainly controlled by BSR. In the model B, the influx of volcanic ash was small, organic matter was mainly degraded by oxygen and the accumulation of organic matter is mainly determined by the production of organic matter.
Occurrence state and oil content evaluation of Permian Fengcheng Formation in the Hashan area as constrained by NMR and multistage Rock-Eval

The Hashan area, neighboring the Mahu Sag that is rich in the shale oil resources, showed commercial oil flow in the corresponding lacustrine shales of the Lower Permian Fengcheng Formation (P_1f)with reserve scale approximately 789 million tons, presenting great potential for oil exploration. Despite their geographical proximity, the hydrocarbon occurrence and oil-bearing capacity of shale in the Hashan area and Mahu Sag greatly differ owing to the complex tectonic evolution. Therefore, understanding the occurrence state and oil content of the P_1f in the Hashan area is crucial for ongoing shale oil exploration activities and the development of the northwestern margin of the Junggar Basin. In this study, an integrated investigation, including petrological observations, scanning electron microscopy (SEM)observation,analysis of nuclear magnetic resonance (NMR)T_1-T_2 spectra, and conventional and multistage Rock-Eval pyrolysis methods were conducted to evaluate the occurrence state and oil content of the P_1f shale in the Hashan area. The results indicate that plagioclase (average 30.7%)and quartz (24.1%) dominate the mineral compositions of the P_1f shale samples. A method involving quartz-plagioclase -carbonate minerals is proposed to conduct lithofacies classification. In the Hashan area, the organic matter abundance in the P_1f shale is scaled in fair to good range, the thermal maturity ranges from immature to early mature stage, and the primary organic matter types are Types I and II1. Intergranular and dissolution pores are the two most common pore types. The free oil is mostly found in the pores and microfractures of the mineral matrix, whereas the adsorbed oil is mostly adsorbed on the surfaces of kerogen and clay minerals. The high organic matter abundance, quartz content, and porosity account for substantial increase in the oil content, the area rich in shale oil resources coincides with that rich in free oil. The most favorable lithofacies in the Hashan area is the calcareous mudstone/shale, which hosts the highest free oil content (average 2.49 mg), total oil content (15.02 mg/g), organic matter abundance (TOC = 1.88% and S_1+S_2 = 20.54 mg/g)and porosity (5.97%).
Microscale crack propagation in shale samples using focused ion beam scanning electron microscopy and three-dimensional numerical modeling

Reliable prediction of the shale fracturing process is a challenging problem in exploiting deep shale oil and gas resources. Complex fracture networks need to be artificially created to employ deep shale oil and gas reserves. Randomly distributed minerals and heterogeneities in shales significantly affect mechanical properties and fracturing behaviors in oil and gas exploitation. Describing the actual microstructure and associated heterogeneities in shales constitutes a significant challenge. The RFPA~(3D)(rock failure process analysis parallel computing program)-based modeling approach is a promising numerical technique due to its unique capability to simulate the fracturing behavior of rocks. To improve traditional numerical technology and study crack propagation in shale on the microscopic scale, a combination of highprecision internal structure detection technology with the RFPA~(3D)numerical simulation method was developed to construct a real mineral structure-based modeling method. First, an improved digital image processing technique was developed to incorporate actual shale microstructures (focused ion beam scanning electron microscopy was used to capture shale microstructure images that reflect the distributions of different minerals)into the numerical model. Second, the effect of mineral inhomogeneity was considered by integrating the mineral statistical model obtained from the mineral nanoindentation experiments into the numerical model. By simulating a shale numerical model in which pyrite particles are wrapped by organic matter, the effects of shale microstructure and applied stress state on microcrack behavior and mechanical properties were investigated and analyzed. In this study, the effect of pyrite particles on fracture propagation was systematically analyzed and summarized for the first time. The results indicate that the distribution of minerals and initial defects dominated the fracture evolution and the failure mode. Cracks are generally initiated and propagated along the boundaries of hard mineral particles such as pyrite or in soft minerals such as organic matter. Locations with collections of hard minerals are more likely to produce complex fractures. This study provides a valuable method for understanding the microfracture behavior of shales.
A developed transient gas-liquid-solid flow model with hydrate phase transition for solid fluidization exploitation of marine natural gas hydrate reservoirs

The multiphase flow characteristic is one of the most concerning problems during solid fluidization exploitation of marine natural gas hydrate reservoirs. In this research, a new transient gas-liquid-solid multiphase flow model with hydrate phase transition was developed. Meanwhile, this model considered the coupling relationship among convective heat transfer, hydrate dynamic decomposition, and multiphase flow. The model can simulate the change of flow pattern from solid-liquid to gas-liquid-solid flow, and describe the distribution character of volume fraction of phase, wellbore temperature and pressure, and hydrate decomposition rate during transportation. The simulation results indicate that the hydrate decomposition region in the wellbore gradually expands, but the hydrate decomposition rate gradually decreases during the solid fluidization exploitation of hydrate. When mining time lasts for 4 h,and the bottom hole pressure decreases by about 0.4 MPa. Increasing NaCl concentration in seawater helps expand hydrate decomposition regions and improves the wellbore hydrate decomposition rate. When the NaCl mass fraction in seawater reaches 15%, it will raise the hydrate decomposition regions to the whole wellbore. In addition, the higher the wellhead backpressure, the lower the decomposition area and decomposition rate of hydrate in the wellbore. When wellhead backpressure reaches 2 MPa, the volume fraction of gas near the wellhead will reduce to about 12%. This work is expected to provide a theoretical basis for the development of marine hydrate reservoirs.
Numerical simulation of rock-breaking and influence laws of dynamic load parameters during axial-torsional coupled impact drilling with a single PDC cutter

Axial and torsional impact drilling technology is used to improve the drilling efficiency of hard rock formation in the deep underground. Still, the corresponding theory is not mature, and there are few correlative research reports on the rock-breaking mechanism of axial and torsional coupled impact drilling tools. Considering the influence of the impact hammer geometry and movement on the dynamic load parameters (i.e., wavelength, amplitude, frequency, and phase difference), a numerical model that includes a hard formation and single polycrystalline diamond compact cutter was established. The Riedel-Hiermaier-Thoma model, which considers the dynamic damage and strength behavior of rocks,was adopted to analyze the rock damage under axial and torsional impact loads. The numerical simulation results were verified by the experimental results. It was found that compared with conventional drilling, the penetration depths of axial, torsional, and axial-torsional coupled impact drilling increased by 31.3%, 5.6%, and 34.7%, respectively. Increasing the wavelength and amplitude of the axial impact stress wave improved the penetration depth. When the bit rotation speed remained unchanged,increasing the frequency in the axial and circumferential directions had little effect on the penetration depth. However, as the frequency increased, the cutting surface became increasingly smooth, which reduced the occurrence of bit vibration. When the phase difference between the axial and circumferential stress waves was 25%, the penetration depth significantly increased. In addition, the bit vibration problem can be effectively reduced. Finally, the adjustment of engineering and tool structure parameters is proposed to optimize the efficiency of the axial-torsional coupled impact drilling tool.
Chelators to assist the high dispersion of Ni_2P particles over mesoporous silica nanospheres for hydrogenating reaction

Ni_2P supported catalysts exhibit high catalytic activities in hydrogenation reaction, of which the particle sizes of Ni_2P active phases are the key influential factor. This research focus on the effect of chelators on the size of Ni_2P particles over wrinkle silica nanoparticles (WSNs)by introducing chelating agents EDTA and NTA during impregnation process. The characterization results show that chelators modified catalysts possess smaller size of Ni_2P particles than the unmodified Ni_2P catalysts. Among all the synthesized catalysts, the EDTA modified Ni_2PE(1.5)/WSNs catalyst possesses smallest average particle size of Ni_2P,only 2.6 nm. Moreover, the Ni_2P catalysts with the assistance of EDTA exhibits better catalytic activity than that of NTA under high reaction temperature, which can be ascribed to the strong bonding between EDTA and Ni. And the EDTA modified Ni_2PE(1.5)/WSNs catalyst shows highest hydrogenation ability,almost reaching 100% decalin selectivity.
Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma

Charcot-Leyden crystals (CLCs) are the hallmark of many eosinophilic-based diseases, such as asthma. Here, we report that reduced glutathione (GSH) disrupts CLCs and inhibits crystallization of human galectin-10 (Gal-10). GSH has no effect on CLCs from monkeys (Macaca fascicularis or M. mulatta), even though monkey Gal-10s contain Cys29 and Cys32. Interestingly, human Gal-10 contains another cysteine residue (Cys57). Because GSH cannot disrupt CLCs formed by the human Gal-10 variant C57A or inhibit its crystallization, the effects of GSH on human Gal-10 or CLCs most likely occur by chemical modification of Cys57. We further report the crystal structures of Gal-10 from M. fascicularis and M. mulatta, along with their ability to bind to lactose and inhibit erythrocyte agglutination. Structural comparison with human Gal-10 shows that Cys57 and Gln75 within the ligand binding site are responsible for the loss of lactose binding. Pull-down experiments and mass spectrometry show that human Gal-10 interacts with tubulin α-1B, with GSH, GTP and Mg~(2+) stabilizing this interaction and colchicine inhibiting it. Overall, this study enhances our understanding of Gal-10 function and CLC formation and suggests that GSH may be used as a pharmaceutical agent to ameliorate CLC-induced diseases.