mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Ten cases of intradiaphragmatic extralobar pulmonary sequestration: a single-center experience

Background Intradiaphragmatic extralobar pulmonary sequestration (IDEPS) is a rare type of pulmonary sequestration (PS). The purpose of this study is to assess diagnosis and operative treatment of IDEPS. Methods Patients with PS who were diagnosed and treated in our center from January 2015 to December 2020 were analyzed retrospectively to identify patients with IDEPS. Results Totally, 215 patients with PS were treated surgically, including 10 cases with IDEPS. Prenatal ultrasounds and postnatal-enhanced CT showed the presence of IDEPS in four cases and in seven cases, respectively. The three-dimensional (3D) reconstruction software was performed perfectly to identify the location of the lesions in 10 cases. The surgeries were performed smoothly by laparoscopic surgery in one case, video-assisted thoracic surgery (VATS) in five cases and Da Vinci robot-assisted thoracoscopic surgery (DVRATS) in four cases. In the VATS group, the average operative duration, intraoperative blood loss volume, length of stay after operation, and postoperative thoracic catheter indwelling duration were 48 min, 3.8 mL,6.4 days and 2.2 days, respectively. That of the DVRATS group were 80 min, 3.5 mL, 4.3 days and 1.5 days, respectively. No side effects had appeared. Conclusions The 3D reconstruction software was proven to be capable in assisting the assessment of IDEPS. We suggested early surgery to treat IDEPS, and the best path was accessing the mass from the chest. Both DVRATS and VATS for the treatment of an IDEPS are safe, feasible, and effective. Furthermore, DVRATS provides a 3D magnified view, more flexibility and precision.
Characterization of Amphidinium (Amphidiniales,Dinophyceae) species from the China Sea based on morphological,molecular,and pigment data

Amphidinium species are amongst the most abundant benthic dinoflagellates in marine intertidal sandy ecosystems.Some of them are able to produce a variety of bioactive compounds that can have both harmful effects and pharmaceutical potentials.The diversity of Amphidinium in shallow waters along the Chinese coast was investigated by isolating single cells from sand,coral,and macroalgal samples collected from 2012 to 2020.Their morphologies were subjected to examination using light microscopy (LM) and scanning electron microscopy (SEM).A total of 74 Amphidinium strains were morphologically identified,belonging to 11 species:A.carterae,A.gibbosum,A.operculatum,A.massartii,A.cf.massartii,A.fijiensis,A.pseudomassartii,A.steinii,A.thermaeum,A.theodori,A.tomasii,as well as an undefined species.The last seven species have not been previously reported in Chinese waters.Amphidinium carterae subclades Ⅰ,Ⅱ,and Ⅳ were found in the South China Sea,while subclade Ⅲ was only found in the Yellow Sea.Threadlike body scales were observed on the surface of subclades Ⅲ and Ⅳ,supporting the idea that A.carterae might contain several different species.Large subunit ribosomal RNA (LSU rRNA) sequencesbased phylogeny revealed two groups (Groups Ⅰ and Ⅱ) within Amphidinium,which is consistent with the relative position of sulcus (in touch with cingulum or not).In addition,large differences in morphology and molecular phylogeny between A.operculatum (the type species of Amphidinium) and other species,suggest that a subdivision of Amphidinium might be needed.The pigment profiles of all available strains were analyzed by high performance liquid chromatography (HPLC).Eleven pigments,including peridinin,diadinoxanthin,diatoxanthin,pheophorbide (and pheophorbide a),antheraxanthin,β -carotene,and four different chlorophylls were detected.The high pheophorbide/pheophorbide a ratio in Amphidinium implies that it may be a good candidate as a natural source of photosensitizers,a well-known anticancer drug.
Precast system and assembly connection of cement concrete slabs for road pavement:A review

Prefabricated pavement is increasingly applied worldwide due to the rapid construction on-site.This paper presents a state-of-the-art review of the precast systems and assembly connection of concrete slabs,as well as the precast pavement features.The previous research indicates that:(1) both super-slab and Michigan systems are recommended with the satisfied road performance close to the cast-in-place;(2) flexible base material is suggested for the fabricated pavement for the satisfied leveling and stress distribution;(3) to prevent the voiding phenomenon of the fabricated pavement,the sand cushion course,dry mixed mortar or self-leveling mortar,and other flowable materials could be used for the secondary leveling of the base after the pavement splicing;(4) two-direction dowel bars are recommended for slab connections of the fabricated pavement,which helps to improve the load transfer capacity of the joints and enhance the durability of the fabricated pavement structure;(5) the sealing treatment of precast slab joints needs strengthening to reduce the impact of surface runoff on the base course;(6) the further research focuses are designing with functional,composite,mechanized,intelligent,lightweight,and flexible pavement slabs.Besides,pavement mechanical properties induced by temperature overlapping traffic loads need to be revealed.
Taxonomic review of Chinese ant genus Probolomyrmex (Hymenoptera:Formicidae)

Four species of the ant genus Probolomyrmex in the subfamily Proceratiinae are recognized in China,namely P.dammermani,P.longiscapus,P.longinodus and P.vieti.Two species,P.dammermani and P.vieti are recorded in China for the first time.A key to the known Chinse species of the genus based on worker caste is presented.
A GPU-based general numerical framework for plasma simulations in terms of microscopic kinetic equations with full collision terms

We have proposed a general numerical framework for plasma simulations on graphics processing unit clusters based on microscopic kinetic equations with full collision terms.Our numerical algorithm consistently deals with both long-range (classical forces in the Vlasov term) and short-range (quantum processes in the collision term) interactions.Providing the relevant particle masses,charges and types (classical,fermionic or bosonic),as well as the external forces and the matrix elements (in the collisional integral),the algorithm consistently solves the coupled multi-particle kinetic equations.Currently,the framework is being tested and applied in the field of relativistic heavy-ion collisions;extensions to other plasma systems are straightforward.Our framework is a potential and competitive numerical platform for consistent plasma simulations.
Two New Borates Built by Different Types of {B_9} Cluster Units

Two new belt-like borates Na_4[B_9O_(14)(OH)_3]·0.5H_2O(1) and Na_5[B_9O_(14)(OH)_4](2) have been synthesized under solvothermal conditions. Both compounds contain unprecedented B_9O_(16)(OH)_n~((n+5))–[n=3(1), 4(2)] clusters, which are constructed from four B_3O_3 rings via three BO_4 tetrahedra. Compound 1 exhibits a rare 1D belt with two types of 8-membered ring(MR) windows based on B_9O_(16)(OH)_3~(8–) clusters. Compound 2 features two different 1D belts built by different B_9O_(16)(OH)_4~(9–) units, which is first discovered in borate family. UV-Vis diffuse reflectance spectra reveal that compounds 1 and 2 have the cut-off edges below 190 nm, indicating that they may have potential application in deep UV(DUV) region.
Sparing lung tissue with virtual block method in VMAT planning for locally advanced non-small cell lung cancer

This study aimed to exploit a new virtual block method to spare normal lung tissue in VMAT planning for patients with locally advanced non-small cell lung cancer (LA-NSCLC).The previous method was used to manually restrict the angle of the beam passing through,which ignored the location and shape of large targets that varied between different slices and did not block the beamlets precisely.Unlike the previous method,this new virtual block method was used to block the beamlets when necessary by closing the multi-leaf collimator (MLC) at prerequisite angles.The algorithm for closing the MLC depended on the thickness of the beamlets passing through the lungs and avoided only the entrance radiation beamlet.Moreover,this block can be automatically contoured.A retrospective study was performed to compare the VMAT plans with and without the virtual block method for 17 LANSCLC patients,named the block plan (B-plan)/non-block plan (N-plan).All cases were selected in this study because of the large tumor size and unmet dose constraints of the lungs.In addition to the maximum dose constraint for the virtual block,B-plans adopted identical optimization parameters to N-plans for each patient.These two types of plans were compared in terms of dosimetric indices and plan scores.The results were statistically analyzed using the Wilcoxon nonparametric signed-rank test.B-plans have advantages in the following dosimetric metrics that have statistical significance (p<0.05):(1) lower V_5/V_(10)/D_(mean)/normal tissue complication probability (NTCP) of total lungs;(2) reductions in V_5/V_(10) for the contralateral lung;(3) decrease in D_(mean)/V_(40) of the heart;(4) decrease in esophagus V_(40);(5) reductions in D_(mean),V_5/V_(10) of normal tissue.B-plans (82.51 ± 7.07) achieved higher-quality scores than N-plans (80.74 ± 7.22).The new virtual block spared the lungs as well as other normal structures in VMAT planning for LA-NSCLC.Thus,the block method may decrease the risk of radiation-related toxicity in patients.
Current status and perspectives of conversion therapy for advanced gastric cancer

The concept and strategy of advanced gastric cancer treatment have gradually undergone profound changes with the in-depth understanding of the biology and heterogeneous characteristics of gastric cancer. Moreover, the development and application of new anticancer drugs, including chemotherapy drugs, molecularly targeted drugs and immunotherapy drugs for advanced gastric cancer are reported. The connotation of conversion therapy refers to the unresectable or borderline resectable tumors for surgical technical and/or oncological reasons, after active and effective chemotherapy and other comprehensive treatment, the primary gastric lesions can be reduced to a lower stage, while the metastatic lesions can be effectively controlled, to achieve R0 resection and improve the long-term survival rate. Current promising research results of conversion therapy are mostly from single-arm phase II clinical studies with small samples or retrospective studies. Conversion therapy still faces many challenges, including limited diagnostic and assessment methods, insufficient evidence of highly effective treatment regimens, difficulty in clarifying surgical indications, etc. Therefore, the integrated conversion therapy for advanced gastric cancer needs to be carried out with the close cooperation of a multidisciplinary team. Prospective, multi-center randomized controlled trial studies should be conducted in the future, and precision medicine such as molecular biology should be combined to provide better anticancer drug regimens and higher-level clinical evidence for conversion therapy of advanced gastric cancer.
Conceptual design and preliminary experiment of icing risk management and protection system

Icing is one of the main external environmental factors that causes aircraft to lose control. The flight safety assurance system under icing condition is particularly important. However, most of the systems do not consider the coupling characteristics of aerodynamics and flight dynamics of icing aircraft. This will affect the accuracy of the calculation results. Besides, the icing risk management system helps the pilot to realize the possible dangers in advance and perform correct maneuvers, based on quantitative assessment and visualization methods of flight risk. The envelope protection system realizes flight safety guarantee based on the real-time boundary protection method of key flight parameters. Finally, based on distributed simulation technology, a flight simulator was used as a platform to integrate the icing risk management system and envelope protection system to realize man-in-the-loop simulation. Two fictional but historically motivated icing scenarios are designed to test the system, and the results demonstrate that the icing risk management and protection system would be useful for aviation safety and can also be used for pilot training and reproducing flight accidents to find the causes.
Micro powder injection molding of boron carbide components with SiC-Al_2O_3-Y_2O_3 sintering additives

Sintering additives and micro-powder injection molding offer an effective method to densify boron carbide (B_4C) and make B_4C components with complex shapes. By adjusting the proportion of three kinds of powders (SiC, Al_2O_3 and Y_2O_3), four kinds of sintering additives were prepared. The feedstock uniformity, debinding behavior, phase composition and microstructure of micro injection molded B_4C components with different sintering additives were studied. The results showed that the defects such as lattice distortion and vacancy were introduced into ball milling, which increase the surface energy and benefit subsequent sintering densification. The feedstock had good uniformity and rheology that met the requirements of micro powder injection molding. After debinding, B_4C components had enough strength and showed certain sintering characteristics. The addition of sintering additives was beneficial to densification and sintering temperature reduction. The addition of sintering additives formed a second phase in the B_4C crystal and at the grain boundary of B_4C crystal, which changed the fracture mode from transgranular fracture to mixed fracture mechanism with transgranular fracture.
In-process adaptive milling for large-scale assembly interfaces of a vertical tail driven by real-time vibration data

Assembly interfaces, the joint surfaces between the vertical tail and rear fuselage of a large aircraft, are thin-wall components. Their machining quality are seriously restricted by the machining vibration. To address this problem, an in-process adaptive milling method is proposed for the large-scale assembly interface driven by real-time machining vibration data. Within this context, the milling operation is first divided into several process steps, and the machining vibration data in each process step is separated into some data segments. Second, based on the real-time machining vibration data in each data segment, a finite-element-unit-force approach and an optimized space-time domain method are adopted to estimate the time-varying in-operation frequency response functions of the assembly interface. These FRFs are in turn employed to calculate stability lobe diagrams. Thus, the three-dimensional stability lobe diagram considering material removal is acquired via interpolation of all stability lobe diagrams. Third, to restrain milling chatter and resonance, the cutting parameters for next process step, e.g., spindle speed and axial cutting depth, are optimized by genetic algorithm. Finally, the proposed method is validated by a milling test of the assembly interface on a vertical tail, and the experimental results demonstrate that the proposed method can improve the machining quality and efficiency of the assembly interface, i.e., the surface roughness reduced from 3.2 μm to 1.6 μm and the machining efficiency improved by 33%.
Detailed modeling of aluminum particle combustion - From single particles to cloud combustion in Bunsen flames

A numerical model for aluminum cloud combustion which includes the effects of interphase heat transfer, phase change, heterogeneous surface reactions, homogeneous combustion, oxide cap growth and radiation within the Euler-Lagrange framework is proposed. The model is validated in single particle configurations with varying particle diameters. The combustion process of a single aluminum particle is analyzed in detail and the particle consumption rates as well as the heat release rates due to the various physical/chemical sub-models are presented. The combustion time of single aluminum particles predicted by the model are in very good agreement with empirical correlations for particles with diameters larger than 10 μm. The prediction error for smaller particles is noticeably reduced when using a heat transfer model that is capable of capturing the transition regime between continuum mechanics and molecular dynamics. The predictive capabilities of the proposed model framework are further evaluated by simulating the aluminum/air Bunsen flames of McGill University for the first time. Results show that the predicted temperature distribution of the flame is consistent with the experimental data and the double-front structure of the Bunsen flame is reproduced well. The burning rates of aluminum in both single particle and particle cloud configurations are calculated and compared with empirical correlations. Results show that the burning rates obtained from the present model are more reasonable, while the correlations, when embedded in the Euler-Lagrange context, tend to underestimate the burning rate in the combustion stage, particularly for the considered fuel-rich flames.
Three-dimensional time-varying sliding mode guidance law against maneuvering targets with terminal angle constraint

This paper deals with the problem of intercepting maneuvering targets with terminal angle constraints for missiles subjected to three-dimensional non-decoupling engagement geometry. To achieve the finite-time interception and satisfactory overload characteristics, a time varying sliding mode control methodology is developed based on a time base generator function. The main feature of the proposed guidance law guarantees the Line-of-Sight (LOS) angles to converge to small neighborhoods of the desired values at the interception time. First, a fractional power extended state observer is used to estimate the unknown target acceleration, which can significantly reduce the adaptive switching gain. The fractional power extended state observer enjoys the advantage of better noise tolerance. Then, a newly designed sliding mode surface is constructed by introducing a time base generator function and the time-varying sliding mode guidance law is developed based on this time-varying sliding surface. The proposed guidance law significantly reduces the overload magnitudes. Numerical simulations are carried out to verify the performance of the proposed guidance law.
Influence of South Asian Biomass Burning on Ozone and Aerosol Concentrations Over the Tibetan Plateau

In this work,the influence of South Asian biomass burning emissions on O_3 and PM_(2.5) concentrations over the Tibetan Plateau (TP) is investigated by using the regional climate chemistry transport model WRF-Chem.The simulation is validated by comparing meteorological fields and pollutant concentrations against in situ observations and gridded datasets,providing a clear perspective on the spatiotemporal variations of O_3 and PM_(2.5) concentrations across the Indian subcontinent,including the Tibetan Plateau.Further sensitivity simulations and analyses show that emissions from South Asian biomass burning mainly affect local O_3 concentrations.For example,contribution ratios were up to 20% in the Indo- Gangetic Plain during the pre-monsoon season but below 1% over the TP throughout the year 2016.In contrast,South Asian biomass burning emissions contributed more than 60% of PM_(2.5) concentration over the TP during the pre-monsoon season via significant contribution of primary PM_(2.5) components (black carbon and organic carbon) in western India that were lofted to the TP by westerly winds.Therefore,it is suggested that cutting emissions from South Asian biomass burning is necessary to alleviate aerosol pollution over the TP,especially during the pre-monsoon season.
Phytohormones Jasmonic Acid,Salicylic Acid,Gibberellins,and Abscisic Acid are Key Mediators of Plant Secondary Metabolites

Until recently,many studies on the role of phytohormones in plant secondary metabolism focused on jasmonic acid (JA),salicylic acid (SA),gibberellins (GA),and abscisic acid (ABA).It is now clear that phytohormone-induced regulation of signaling occurs via regulation of the biosynthetic pathway genes at the transcriptional level or through posttranslational regulation,or an increase in secondary metabolite deposition (e.g.,trichomes).Here,we summarize recent advances,updating the current reports on the molecular machinery of phytohormones JA,SA,GA,and ABA involved in plant secondary metabolites.This review emphasizes the differences and similarities among the four phytohormones in regulating various secondary metabolic biosynthetic pathways and also provides suggestions for further research.
含烃流体与方解石的相互作用模拟实验及其地质意义

深层-超深层含油气盆地埋藏演化过程中,含烃流体与储层间的相互作用深刻影响着油气和储层的质量演化,仍是需要进一步研究的科学问题.文章以烷烃-水溶液-方解石体系为例,应用熔融石英毛细管实验技术和光谱分析技术,结合扫描电镜观察等分析手段,探讨了高温条件下,有水体系和无水体系中方解石与烃类间相互作用过程与机理.结果表明,体系中有水存在时,将发生广泛的有机-无机相互作用,且不同的无机组分对烃类裂解有不同的影响.蒸馏水能够促进自由基热裂解和水氧化反应,生成更多的低分子量烃类、二氧化碳以及羧酸等有机酸,并抑制自由基铰链反应,生成较少高分子烃类;氯化钙盐水中,由于自由基的生成受到高浓度钙离子的抑制,烃类气体产量较蒸馏水体系低.方解石在不同流体环境中的表面反应性不同,决定着其对烃类裂解的不同催化效果.在烷烃-无水体系中,方解石能够促进生成更多裂解气和高分子量烃类,而在烷烃-有水体系中,方解石既能促进生成裂解气也能抑制高分子量烃类的生成,并与有机酸发生表面反应,导致方解石的溶解.因此,深层油气藏埋藏演化过程中,有机-无机作用除受温度压力控制外,还将受到地层水丰度、类型、矿化度和矿物等多因素的共同控制,并导致烃类裂解和储集性能的差异演化.
不同规格羌活微型饮片质量评价

目的评价不同规格羌活Notopterygium incisum微型饮片的质量。方法建立3个产地不同规格样品的HPLC指纹图谱,测定干膏率及浸出物、异欧前胡素、羌活醇含量,采用相似度评价、聚类分析、主成分分析、偏最小二乘判别分析进行化学计量学研究。结果36批样品HPLC指纹图谱中有18个共有峰,指认出6种成分。各批样品可聚为2类,5个主成分因子累积方差贡献率为80.71%,质量差异标志性成分有8个。各产地样品质量依次为甘肃礼县>青海西宁>四川理县,最优规格分别为S12、S17、S32。结论该方法稳定可靠,可用于羌活微型饮片的质量控制,最佳规格为0.5 cm×0.5 cm×0.3 cm。
自发性冠状动脉夹层研究进展

自发性冠状动脉夹层(SCAD)是非动脉粥样硬化性急性冠状动脉综合征和急性心肌梗死的重要原因。SCAD主要发生在中青年女性,病因尚不清楚,其典型心血管危险因素发生率低于动脉粥样硬化性心肌梗死患者。近年来伴随冠状动脉造影和高分辨冠状动脉腔内成像应用的增加,SCAD的诊断和研究数量激增,极大提高了对SCAD认识。该文综述了SCAD的流行病学、病理生理学、临床表现、诊断、鉴别诊断、治疗及预后的最新研究进展。
Nanomedicine enables efficient CRISPR-Cas9 genome editing for disease treatment

In recent years, the clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR-Cas9) technology that won the 2020 Nobel Prize in Chemistry has served as one of the most prominent and powerful tools in gene editing for biomedical research and the treatment of various diseases [1 ]. Nevertheless, it remains a substantial challenge to effectively and safely deliver CRISPR-Cas9 molecules into target cells [2]. Viral-based carriers have been broadly used in CRISPR-Cas9 delivery, but there are still some intrinsic flaws, such as low packing capacity, tumorigenesis, immunogenicity, and off-target editing effects, which greatly hinder their clinical translation [3]. Alternatively, a nonviral nanomaterial-based delivery strategy is becoming increasingly promising due to its low toxicity, high delivery efficiency, specific targeting and minor stimulation of the immune response [4]. Engineered nanomaterial delivery systems hold great potential to advance the implementation of CRISPR-Cas9 technology. From this perspective, we discuss and highlight how the latest promising nanomaterial systems overcome some long-term challenges in CRISPR-Cas9 gene editing and provide our point of view on the remaining obstacles and future directions for the clinical implementation of nano-medicine-based CRISPR-Cas9 modalities.