mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
In Vitro Infectious Risk Assessment of Heliothis virescens ascovirus 3j (HvAV-3j) toward Non-target Vertebrate Cells

As specific pathogens of noctuid pests, including Spodoptera exigua, S. litura, Helicoverpa armigera, and Mythimna separata, ascoviruses are suitable for the development of bioinsecticides. In this study, the infectivity of Heliothis virescens ascovirus 3j(HvAV-3j) on insect and mammalian cells was evaluated. HvAV-3j infection induced drastic morphological changes in Sf9, HzAM1, SeFB, and HaFB cells, including swelling and detachment. Notably, the latter phenomena did not occur in HvAV-3j-inoculated mammalian cells(HEK293, 7402, HePG2, PK15, ST, and TM3). MTT assays indicated that HvAV-3j inhibited the growth of host insect cells from the 6th hpi, but no effects were detected in the HvAV-3j-inoculated mammalian cells. Furthermore, viral DNA replication, gene transcription, and protein expression were investigated, and the results consistently suggested that HvAV-3j viruses were not able to replicate their genomic DNA, transcribe, or express their proteins in the non-target vertebrate cells. The HvAV-3j genes were only transcribed and expressed in the four insect cell lines. These results indicated that HvAV-3j was infectious to cells derived from S. frugiperda, S. exigua, H. armigera, and H. zea but not to cells derived from human, pig, and mouse, suggesting that ascoviruses are safe to nontarget vertebrate cells.
Pros and Cons: Autophagy in Acute Spinal Cord Injury

Autophagy plays an important role in the development and pathogenesis of various diseases. It can be induced by a variety of events such as hypoxia, nutrient-starvation, and mechanical damage. Many neurological disorders such Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, cerebral ischemia, and acute spinal cord injury(ASCI), are closely related to autophagy. However, therapeutic strategies to manipulate autophagy have not yet been fully deciphered due to the limited knowledge of the molecular mechanisms underlying autophagy in these disorders.
Paraventricular Thalamus as A Major Thalamic Structure for Wake Control

The thalamus is the gate of the cerebral cortex, the ultimate target for the neural networks controlling behavioral states and cognitive functions. According to the reticular theory initially proposed by Moruzzi and Magoun, excitatory inputs from large reticular zones of the brainstem via widespread intra- and extra-thalamocortical systems finally activate the cerebral cortex to cause generalized cortical activation and wakefulness [1]. This theory proposes a central relay role to the thalamus for cortical activation as supported by early studies using neurodegeneration techniques and by the elegant work of Steriade's group and other investigators illustrating the electrophysiological mechanisms of the thalamocortical system at the cellular level during wakefulness, rapid eye-movement sleep(REMs) and non-REM sleep(NREMs) [2]. Yet, more selective lesion studies conducted between 1960 and the 2000s by many research teams have questioned the importance of the thalamus because these thalamic lesions do not result in loss of cortical activation and wakefulness [3]. Moreover, the identification of other wake-promoting systems, such as those of the hypothalamic hypocretin(Hcrt) and histamine neurons [4], has diverted attention from the thalamus to other structures and thus ‘‘dilute'' its importance. Recently, the use of innovative approaches such as optogenetics and chemogenetics combined with transgenic animal models has demonstrated the effects of cell-type-specific and real-time activation and/or inactivation of selective cellular targets along with their pathways. Thus, the time appears opportune to assess whether the previous lesion methods involved large-scale damage of all thalamic cells, leading therefore to biased conclusions on the thalamic control of wakefulness.
Effects of Integrated Organic and Inorganic Fertilizers on Yield and Growth Parameters of Rice Varieties

We investigated the effects of integrated organic and inorganic fertilizers on the growth and yield of indica rice variety Manawthukha and japonica rice variety Genkitsukushi. In a split-plot design, the two rice varieties were assigned as main plot factors, and the integrated treatments were the subplot factors, including no-N fertilizer(N_0 ), 50% chemical fertilizer(CF)(CF_(50) ), 100% CF(CF_(100) ), 50% CF + 50% poultry manure(PM)(CF_(50) PM_(50) ), 50% CF + 50% cow manure(CM)(CF_(50) CM_(50) ), and 50% CF + 50% compost(CP)(CF_(50) CP_(50) ). CF_(100) was equivalent to N at 85 kg/hm 2 . Manure was applied based on the estimated mineralizable nitrogen(EMN) level, which is dependent on total N(%) of each manure type. Manawthukha rice plants were taller with higher tiller number and dry matter content. However, higher soil-plant analysis development(SPAD) values were measured in Genkitsukushi throughout the crop growth period, resulting in higher seed-setting rate(%) and greater yield. At the same N level, CF_(50) PM_(50) application in both rice varieties resulted in higher SPAD values, plant height and tiller number than CF_(100) . CF_(50) PM_(50) containing total N more than 4% supplied synchronized N for the demands of the rice plants, resulting in maximum dry matter, yield and yield components. CF_(50) CM_(50) and CF_(50) CP_(50) treatments containing total N less than 4% resulted in lower yields which were similar to CF_(100) . These results indicated that integrating organic and inorganic fertilizers enhanced growth parameters and yields of Manawthukha and Genkitsukushi, while reducing the dose of chemical fertilizer.
Organic Carbon in the Surface Sediments from the Intensive Mariculture Zone of Sanggou Bay:Distribution,Seasonal Variations and Sources

Mariculture has rapidly grown worldwide,which might greatly influence the biogeochemical cycle of organic carbon in coastal seas.In this study,several geochemical parameters,including grain size composition,sedimentary total organic carbon (TOC),total nitrogen (TN),stable carbon (δ~(13)C) and nitrogen (δ~(15)N) isotopic compositions,were analyzed for surface sediments collected from different mariculture zones of Sanggou Bay and in different seasons.We investigated the composition and distribution of organic matter in surface sediments and further evaluated the contribution of mariculture activities to TOC sources.The TOC and TN contents (mass percentage) in the bay were in the range of 0.14% to 1.45% and 0.03% to 0.20%,respectively.The spatial distribution indicated that sedimentary TOC and TN contents in shellfish monoculture and shellfish-kelp polyculture zones were higher than in other mariculture zones,which might be related to grain size composition and mariculture organisms.Seasonal variations of TOC contents were observed in different mariculture zones.The TOC/TN atomic ratio (C/N),δ~(13)C and δ~(15)N were in the ranges of 5.97 to 10.97,–21.76‰ to –13.14‰ and 2.13‰ to 8.08‰,respectively,implying that sedimentary organic matter in Sanggou Bay was the mixture of marine phytoplankton,terrestrial and maricultural sources.A simple mixing model based on δ~(13)C was applied and the results indicated that the relative contributions of organic carbon sources in Sanggou Bay followed the order kelp (36.6%) >marine phytoplankton (28.7%) >shellfish bio-deposition (23.8%) >terrestrial input (10.9%).Surface sediments in Sanggou Bay were dominated by mariculture-derived organic carbon,which on average accounted for 60.4% of TOC.
Body-Fitted Momentum Source Method for Predicting Rotor Aerodynamics Characteristics in Hover

To gain high efficiency for the simulation of the aerodynamic characteristics of the rotor in hover,body fitted momentum source(BFMS)method is proposed. In this method,the actual blade geometry is represented by the single layer of volume grid surrounding the blade. Aiming at correctly simulating the aerodynamic characteristics of the discrete cells along the chordwise of blade airfoil section,a new distributed force model is proposed. For comparison,the RANS method with S-A turbulence model and the steady rotor momentum source(SRMS)method based on embedded grid systems are established,respectively. And the grid connecting methodology is improved to embed the blade into the background grids for the three methods. Then,simulations are performed for the hovering Caradonna - Tung rotor by these methods,and the calculated results are compared with the available experimental data. Moreover,the pressure distributions along the blade are compared with the conventional momentum source methods. It is demonstrated that the BFMS method can be employed as an effective approach to predict rotor aerodynamic characteristics with a low computational resource and reasonable accuracy.
Low-Complexity DOA Estimation of Noncircular Signals for Coprime Sensor Arrays

This paper presents a low-complexity method for the direction-of-arrival(DOA)estimation of noncircular signals for coprime sensor arrays. The noncircular property is exploited to improve the performance of DOA estimation. To reduce the computational complexity,the rotational invariance propagator method(RIPM)is included in the algorithm. First,the extended array output is reconstructed by combining the array output and its conjugated counterpart. Then,the RIPM is utilized to obtain two sets of DOA estimates for two subarrays. Finally,the true DOAs are estimated by combining the consistent results of the two subarrays. This illustrates the potential gain that both noncircularity and coprime arrays provide when considered together. The proposed algorithm has a lower computational complexity and a better DOA estimation performance than the standard estimation of signal parameters by the rotational invariance technique and Capon algorithm. Numerical simulation results illustrate the effectiveness and superiority of the proposed algorithm.
颅脑外伤合并脑裂畸形因果关系鉴定1例

鉴定此类案件时,需仔细审阅被鉴定人颅脑损伤当时的影像学资料及临床体格检查情况以明确自身脑疾病的类型和程度等,再进一步根据本次颅脑损伤可能带来的损害后果确定是否足以引起被鉴定人目前的肢体功能障碍、精神障碍等表现。最后,综合疾病严重程度与外力作用,分析判断其目前遗留的损害后果分别与其自身疾病和外伤之间存在何种因果关系。
关注城镇污水处理厂运营困境,共同探寻破解之道

随着城镇化进程的不断加速以及水污染问题的日益突出,我国城镇污水处理设施近十多年来持续高速建设。目前,全国共建成并投入运营4 000多座城镇污水处理厂,日总污水处理规模超过2亿m~3,位居世界第一,约占全球总污水处理规模的1/5。20多万名污水处理从业人员在一线日夜运营维护,大量基层执法人员动态严格监管,对保护水环境发挥着决定性作用,他们是控制水污染的主力军。如果不建设这些设施,如果不能保障已建成的这些设施持续运营,我们的水环境状况将无法想象。
Formation of Better Streets: Interpretation of Urban Design Guidelines for Beijing Street Regeneration and Governance

As a showcase for public well-being and urban identity, a better street should carry not only the constantly flowing traffic stream, but also diversified lifestyles and various streetscapes. Beijing is the capital of China, one of its ancient capitals, and a tier 1 international metropolis, both its street connotation and functions are extremely complex. Along with new requirements proposed in the Beijing City Master Plan (2016-2035) for controlling construction land, strengthening urban identity, and improving urban governance, the Urban Design Guidelines for Beijing Street Regeneration and Governance (the Guidelines ) is not only an important breakthrough point for promoting urban transformation to sustainable urban regeneration and governance, but also the foundation of optimizing capital city construction and building a world-class, harmonious, and livable capital city. Taking full consideration of value orientation, technical methods, system design, and governance transformation, the Guidelines adopts five measures, including identity enhancement, coordinated design, enhancing cultural and aesthetic quality, building platforms, and managing “stubborn diseases”-problems which have plagued people for many years and have been intensifying with years to pass, to comprehensively improve the street design and governance, in the hope of making it a real typical space that represents the image and cultural charm of the capital city.
Preparation and characterization of sodium silicate/epoxy resin composite bonded Nd-Fe-B magnets with high performance

As an organic binder for bonded Nd-Fe-B magnets, epoxy resin (EP) has poor heat resistance but good moisture resistance, while sodium silicate (SS) has poor moisture absorption but better heat resistance and corrosion resistance. In order to improve high temperature stability and decrease moisture absorption of bonded Nd-Fe-B magnets, EP/SS composites were applied as the binder to prepare bonded Nd-Fe-B magnets. The magnetic properties, moisture absorption, corrosion resistance, compressive strength and microstructure of composite bonded magnets were investigated. The results show that EP/ SS bonded magnets can obtain excellent magnetic properties at room temperature, and even useable magnetic properties a thigh temperature environments at 200 ℃. EP/SS composite binder effectively improves heat resistance and corrosion resistance of bonded Nd-Fe-B magnets, and reduces the hygroscopic properties. The molecule of sodium silicateis rigid and keeps it original shape at high temperature environments. In addition, SS in composite binder improves the mobility of the magnetic powders during the pre-pressing process, which makes the magnetic powders attain a more regular structure. These two factors will increase the mechanical properties. Moreover, sodium silicate in the composite binder can also cover the surfaces protecting the magnetic powders from oxidation and corrosion. EP in composite binder can cover SS surface to reduce the water absorption of SS as epoxy is a hydrophobic material. The EDX analysis shows that the composite binder has accumulated in the gaps of the magnet powders, which not only improves heat resistance and corrosion resistance, but also increases the mechanical properties. Therefore, EP/SS composite binder endows bonded Nd-Fe-B magnets excellent comprehensive properties.
Unique structural and magnetic traits of Nd~(3+)-substituted CoeZn nanoferrites

Because of the technological potential of magnetic spinel nanoferrites, we prepared neodymium ion (Nd~(3+))-substituted cobalt-zinc ferrites (CZFs) with the form Co_(0.5)Zn_(0.5)Nd_xFe_2-x)O_4 (0.0 ≤ x ≤ 0.05) via a hydrothermal method. The as-prepared samples were thoroughly characterized using various analytical techniques. XRD, FTIR and FESEM analyses confirm the formation of a cubic spinel phase of the CZFNPs (CZF nanoparticles). A decrease in the lattice parameter due to the substitution of Fe~(3+) by Nd~(3+) in the lattice structures is manifested in the XRD refinement data. The magnetic properties of the proposed CZFNPs were evaluated in terms of the saturation magnetization, remanence, coercivity, squareness ratio and magnetic moment. These CZFNPs exhibit superparamagnetic behaviors at room temperature. Moreover, the Nd~(3+) inclusion does not significantly affect the measured magnetizations and coercivities of the CZFNPs. Samples containing 0.01 and 0.03 Nd~(3+) exhibit lower saturation magnetizations than that of the pristine product. The squareness ratios much less than 0.53 are ascribed to surface spin disordering. The unique magnetic traits of the synthesized CZFNPs are primarily attributed to the substitution of Fe~(3+) ions, with smaller ionic radii, by Nd~(3+) ions, with larger ionic radii. The proposed CZFNPs may be useful for diverse magneto-optic applications.
Fabrication of Ce-doped (Gd_2Y)Al_5O_(12)/Y_3Al_5O_(12) composite-phase scintillation ceramic

In this paper, a novel Ce(Gd_2Y)Al_5O_(12)/Ce:Y_3Al_5O_(12)(Ce:GYAG/Ce:YAG) composite scintillation ceramic was designed and fabricated by a solid-state reaction method. The phase, luminescence and scintillation properties were investigated. The Ce:GYAG/Ce:YAG composite ceramic consisting of two-phase has a broad emission band ranging from 500 to 750 nm. The total mass attenuation coefficient of Ce:GYAG/ Ce:YAG is 0.3864 cm~(-1), in between those of Ce:YAG and Ce:GYAG ceramics. In addition, the composite ceramic had a high light yield of 20430 ph/MeV. By controlling the ratio of GYAG and YAG, the composite ceramic can realize a spectrum design and total mass attenuation coefficient control to meet the requirements for wide-X-ray-energy-range detectors.
A Monte Carlo study of spring-exchange magnets containing ultra-high coercive phases

The aim of the present work is to study magnetization processes in the spring-exchange magnetic composites containing magnetically soft, hard and ultra-high coercive phases, experimentally found in Tb-Fe-B-Nb group of alloys. In order to modeling hysteresis loops a special Monte Carlo procedure, suitable for irregular geometry of the composites, was applied. The obtained results indicate that sufficiently strong coupling between soft and hard magnetic phase leads to collective, single-phase-like movement of such phases, which in turn, causes increase of the coercivity and internal magnetic energy.
养老机构认知症老年人受虐待风险现状及影响因素研究

目的调查养老机构认知症老年人受虐待风险及其影响因素。方法采用照顾者虐待老年人评估量表(CASE)、中文版Zarit护理负担量表(ZBI)、神经精神问卷(NPI)对南京市3所民营养老机构213名认知症老年人及其167名照护者进行调查。结果78.4%的认知症老年人存在受虐待风险;认知症老年人的年龄、病情、精神行为症状及照护者护理负担是主要影响因素(P<0.05,P<0.01)。结论认知症老年人受虐待风险较高,需关注认知症老年人的精神行为症状,减轻照顾者护理负担,以降低老年人受虐待风险。
Neural Network-Based Adaptive Motion Control for a Mobile Robot with Unknown Longitudinal Slipping

When the mobile robot performs certain motion tasks in complex environment, wheel slipping inevitably occurs due to the wet or icy road and other reasons, thus directly influences the motion control accuracy. To address unknown wheel longitudinal slipping problem for mobile robot, a RBF neural network approach based on whole model approximation is presented. The real-time data acquisition of inertial measure unit (IMU), encoders and other sensors is employed to get the mobile robot's position and orientation in the movement, which is applied to compensate the unknown bounds of the longitudinal slipping using the adaptive technique. Both the simulation and experimental results prove that the control scheme possesses good practical performance and realize the motion control with unknown longitudinal slipping.
肺诺卡菌病一例

回顾性分析1例肺诺卡菌病的临床病理特征。患者女,67岁。发热6 d入院。CT示右主支气管堵塞,右肺见有片状软组织密度影。肺穿刺活检示肺泡间隔纤维组织增生,肺泡问多量中性粒细胞为主的炎性细胞浸润伴微脓肿形成。弱抗酸染色示红色细丝状分枝的菌体。痰细菌培养证实为豚鼠耳炎诺卡菌。肺诺卡菌病是一种少见的人畜共患病,需要与肺结核、放线菌病、特发性间质性肺炎等鉴别。
颌面部葡萄酒色斑一例

葡萄酒色斑是一种毛细血管畸形,晚期增厚型常形成多发隆起性结节,易与恶性血管肿瘤等相混淆,形态学以真皮层及皮下筋膜层蜂窝状扩张增生的血管为主,诊断需结合临床外观、病史及病理特征综合判断。该文对近期确诊的1例颌面部葡萄酒色斑患者进行报道,探讨其临床病理特征,以提高对该类疾病的认识。
老年食管癌术后感染患者强化营养治疗一例

营养支持治疗在老年危重症患者支持治疗中具有重要的作用,通过观察1例75岁男性食管癌术后切口感染患者,针对患者存在营养不良风险,脱离呼吸机困难,经积极控制感染和强化营养治疗,病情好转,营养改善,创口愈合,成功脱离呼吸机。
EGFR突变型非小细胞肺癌脑转移的靶向治疗和免疫治疗进展

表皮生长因子受体(EGFR)突变型非小细胞肺癌(NSCLC)容易出现脑转移,EGFR酪氨酸激酶抑制剂(TKI)(EGFRTKI)则为此类患者的治疗带来极大获益。但第一、二代靶向药物脑穿透力弱和最终获得性耐药,导致颅内疾病进展,是脑转移治疗的主要挑战。近年来,随着第三代EGFR-TKI、免疫检查点抑制剂(ICB)的深入研发,EGFR突变型NSCLC脑转移的治疗发生了极大变化。本文将回顾脑转移的靶向治疗及免疫治疗方面取得的进展,并对目前存在的问题及未来发展方向进行探讨。
On Time-Constant Robust Tuning of Fractional Order [Proportional Derivative] Controllers

This paper deals with analyzing a newly introduced method for tuning of fractional order [proportional derivative](FO[PD])controllers to be used in motion control. By using this tuning method, not only the phase margin and gain crossover frequency are adjustable, but also robustness to variations in the plant time-constant is guaranteed. Conditions on the values of control specifications(desired phase margin and gain crossover frequency)for solution existence in this tuning method are found. Also, the number of solutions is analytically determined in this study. Moreover, experimental verifications are presented to indicate the applicability of the obtained results.
Solving Multi-Area Environmental/Economic Dispatch by Pareto-Based Chemical-Reaction Optimization Algorithm

In this study, we present a Pareto-based chemicalreaction optimization(PCRO)algorithm for solving the multiarea environmental/economic dispatch optimization problems. Two objectives are minimized simultaneously, i.e., total fuel cost and emission. In the proposed algorithm, each solution is represented by a chemical molecule. A novel encoding mechanism for solving the multi-area environmental/economic dispatch optimization problems is designed to dynamically enhance the performance of the proposed algorithm. Then, an ensemble of effective neighborhood approaches is developed, and a selfadaptive neighborhood structure selection mechanism is also embedded in PCRO to increase the search ability while maintaining population diversity. In addition, a grid-based crowding distance strategy is introduced, which can obviously enable the algorithm to easily converge near the Pareto front. Furthermore, a kinetic-energy-based search procedure is developed to enhance the global search ability. Finally, the proposed algorithm is tested on sets of the instances that are generated based on realistic production. Through the analysis of experimental results, the highly effective performance of the proposed PCRO algorithm is favorably compared with several algorithms, with regards to both solution quality and diversity.
Modelling of a Human Driver's Interaction with Vehicle Automated Steering Using Cooperative Game Theory

The introduction of automated driving systems raised questions about how the human driver interacts with the automated system. Non-cooperative game theory is increasingly used for modelling and understanding such interaction, while its counterpart, cooperative game theory is rarely discussed for similar applications despite it may be potentially more suitable. This paper describes the modelling of a human driver's steering interaction with an automated steering system using cooperative game theory. The distributed Model Predictive Control approach is adopted to derive the driver's and the automated steering system's strategies in a Pareto equilibrium sense, namely their cooperative Pareto steering strategies. Two separate numerical studies are carried out to study the influence of strategy parameters, and the influence of strategy types on the driver's and the automated system's steering performance. It is found that when a driver interacts with an automated steering system using a cooperative Pareto steering strategy, the driver can improve his/her performance in following a target path through increasing his/her effort in pursuing his/her own interest under the driver-automation cooperative control goal. It is also found that a driver's adoption of cooperative Pareto steering strategy leads to a reinforcement in the driver's steering angle control, compared to the driver's adoption of non-cooperative Nash strategy. This in turn enables the vehicle to return from a lane-change maneuver to straight-line driving swifter.
Eocene Antarctica: a window into the earliest history of modern whales

The Eocene-Oligocene Southern Ocean is thought to have played a major role in cetacean evolution. Yet, fossils from its heart—Antarctica—are rare, and come almost exclusively from the Eocene La Meseta and Submeseta formations of Marambio (Seymour) Island. Here, we provide a summary and update of this crucial fossil assemblage, and discuss its relevance in the broader context of cetacean evolution. To date, Eocene specimens from Antarctica include basilosaurids, a group of archaic stem cetaceans that had already fully adapted to life in water; and the archaic toothed mysticete Llanocetus, the second oldest crown cetacean on record (ca. 34 Ma). This Eocene co-occurrence of stem and crown cetaceans is highly unusual, and otherwise only observed in Peru. Though related, at least some of the Antarctic species appear to be different from, and notably larger than their Peruvian counterparts, suggesting an early differentiation of the high latitude cetacean fauna.