mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
髓系/NK细胞急性白血病一例

患者,男,48岁.因体检发现外周血白细胞增多4 d于2007年11月6日人院.患者入院前1个多月,因接触"肝炎"患者后自觉低热(但检测体温正常),伴乏力、双下肢肌肉胀痛,刷牙时偶有齿龈出血,外院检查发现Anti-HBs(+),ALT 90 U/L,未予以特殊处理.11月2日单位体检血常规示WBC 45.7×10~9/L,RBC 2.29×10~12/L,Hb 94 g/L,中性粒细胞1.8×10~9/L,BPC 32×10~9/L,细胞分类幼稚淋巴细胞占0.85,考虑为急性白血病,为进一步诊治收住我院.病程中无骨痛、无鼻出血或皮肤出血点,食欲、睡眠正常.既往有高血压病史十余年,最高血压180/90 mm Hg(1 mm Hg=0.133kPa),现规则服用硝苯地平缓释片治疗,血压控制在140/90mm Hg左右;有吸烟史20余年,平均每日20支.
锂剂和雷帕霉素联合应用治疗亨廷顿病的合理机制

背景和目的:亨廷顿病(HD)是由于huntingtin蛋白中多聚谷氨酰胺扩增突变引起的.多聚谷氨酰胺的扩增突变具有功能获得性毒性,使蛋白质有易聚集倾向.易聚集蛋白质难以通过泛素-蛋白酶体途径进行降解,而依赖于大自噬清除.自噬诱导剂--雷帕霉素抑制哺乳动物雷帕霉素靶位(mTOR),进而上调自噬,减弱易聚集蛋白质的毒性.
皮肤长"刺"一例

患者男，70岁。因躯干、双上肢长“刺”2周于2007年11月10日来我科就诊。3年前患者双手指、手掌多处被仙人掌刺伤，当时拔除刺，刺伤处很快愈合。2007年10月中旬患者感觉背部、上臂有刺痛感，仔细查看发现有“刺”样的东西，共有10余个，长约0.5-0.8 cm，“刺”的根部皮肤发红，自行拔除，但反复有新“刺”在其他部位出现。
含CelluZyme成分面膜辅助药物治疗痤疮疗效观察

痤疮作为一种损容性皮肤病,不仅影响容貌,而且影响患者心身健康,因此痤疮治疗及皮肤护理一直是倍受关注的焦点.随着科学发展,现代皮肤科医生的治疗理念应该将皮肤健康与美容结合在一起,在治疗的同时合理使用护肤品,起到辅助治疗并减少疾病复发的作用
酶联免疫斑点技术及其在结核分枝杆菌感染诊断中的研究进展

结核病已经成为一个严重的公共卫生问题,我国已有1/3人口感染了结核菌,受感染人数超过了4亿,据研究受感染人口中有10%的人发生结核病.
高危型人乳头瘤病毒载量与宫颈病变的关系

目前为止,已发现和鉴定出100多种人乳头瘤病毒(HPV)类型,其中有40多种与生殖道感染有关,还有近15种可导致肿瘤发生.人们将导致肿瘤发生的HPV类型称为高危型HPV[1].
姜黄素抗纤维化作用研究进展

姜黄素(curcumin)是从姜科植物(Curcuma Longa L.)的根茎姜黄中提取的一种植物多酚,分子式为C21H20O6,分子量为368.39.姜黄素广泛用于食品上色和佐味,也作为医用.印度传统医学认为,姜黄根粉的作用按现代医学术语来说,可以用于治疗胆疾患、厌食、鼻炎、咳嗽、糖尿病、肝疾患、风湿病和鼻窦炎.在中国的传统医学中,姜黄主要用于与腹痛、黄疸等相关疾病的治疗.有关姜黄素的药理学研究表明[1],姜黄素具有多方面药理作用,如抗炎、抗氧化、清除自由基、抗肿瘤等作用,并对心血管系统、消化系统有作用.
Neutron production at the heavy ion research facility in Lanzhou

In this work, the neutron radiation field at Heavy Ion Research Facility in Lanzhou (HIRFL) was investigated. Total neutron yields, spectra and angular distributions in the bombardment of various thick targets by ~(12)C and ~(18)O ions with energies up to 75 MeV/u were obtained using the activation method. The neutron dose equivalent rates of 60 MeV/u ~(18)O on various thick targets at different angles were measured with a modified A-B remmeter. Our results are compared with those of other reports.
Backward Compton scattering and QED with noncommutative plane in the strong uniform magnetic field

In the strong uniform magnetic field, the noncommutative plane (NCP) caused by the lowest Landau level (LLL) effect, and QED with NCP (QED-NCP) are studied. Being similar to the condensed matter theory of quantum Hall effect, an effective filling factor f(B) is introduced to characterize the possibility that the electrons stay on the LLL. The analytic and numerical results of the differential cross section for the process of backward Compton scattering in accelerator with unpolarized or polarized initial photons are calculated. The existing data of BL38B2 in Spring-8 have been analyzed roughly and compared with the numerical predictions primitively. We propose a precise measurement of the differential cross sections of backward Compton scattering in a strong perpendicular magnetic field, which may reveal the effects of NCP.
Relation between silico-aluminous fly ash and its coal of origin

Fly ashes are typical complex solids which incorporate at the same time intrinsic properties derived from the layers (various mineralogical and dimensional spectra) and major transformations generated during prior processing. To use fly ashes in various applications, it is necessary to characterise them completely. The first research to date carried out on silico-aluminous fly ashes in order to characterise them physically, morphologically, chemically and mineralogically, resulted in the recognition that they are relatively simple materials. In the present study, a silico-aluminous fly ash coming from the power station of Albi (France) was selected. Heat treatment at 450 and 1200 °C together with coal simulated the treatment undergone by coal in the power station in order to mimic real coal residue. In conclusion, the diversity of the particles contained in fly ash could only be explained by the relation existing between the fly ash and its coal of origin.
Dielectric and Piezoelectric Properties of Sodium Bismuth Titanate Ceramics with KCe Substitution

The piezoelectric properties of the (KCe)-substituted sodium bismuth titanate (Na_(0.5)Bi_(4.5)Ti_4O_(15), NBT) piezoelectric ceramics are investigated. The piezoelectric properties of NBT ceramics are significantly enhanced by (KCe) substitution. The Curie temperature T_c, and piezoelectric coefficient dss for the (KCe)-substituted NBT are found to be 663°C, and 27pC/N, respectively. Dielectric and annealing spectroscopy present that the (KCe) co-substituted NBT piezoelectric ceramics possess stable piezoelectric properties.
New Sedov-Type Solution of Isotropic Turbulence

The starting point lies in the results obtained by Sedov (1944) for isotropic turbulence with a self-preserving hypothesis. A careful consideration of the mathematical structure of the Karman–Howarth equation leads to an exact analysis of all cases possible and to all admissible solutions of the problem. I study this interesting problem from a new point of view. New solutions are obtained. Based on these exact solutions, some physical significant consequences of recent advances in the theory of self-preserved homogeneous statistical solution of the Navier–Stokes equations are presented.
Interaction of O~(3+) Ions with Al_2O_3 Nanocapillaries

We investigate angular distributions of the transmitted 60 keV and 120 keV O~(3+) ions through nanocapillaries with 50nm diameter and 10μm length. The experimental results are in agreement with the 'guiding effect' found by Stolterfoht et al. For different tilted angles of the nanocapillary membrane with respect to the beam, the angular distributions of the transmitted ions are measured by a one-dimensional micro-channel plate (MCP) detector. Moreover, the dependence of this guiding effect on the projectile energy is studied.
DFT Study on Intermolecular Cleavage Reaction of N-(2-Hydroxyphenyl)-phthalamic Acid

The reaction mechanisms of intermolecular cleavage reaction of N-(2-hydroxyphenyl)-phthalamic acid were studied via the density functional theory(DFT). All geometries of the reactant, transition states, and products were optimized at the B3LYP/6-31G(d, p) level. Vibration analysis was carried out to confirm its identity as transitions' structure, and the intrinsic reaction coordinate method(IRC) was used to search the minimum energy path. Two possible reaction channels are reported in this article. The calculated results indicate that O-cyclization reaction channel has the lower activation barrier, and therefore, it occurs more easier than the other.
Electrochemical Study on the Interaction of Protein with Bromothymol Blue and Its Analytical Application

The interaction of bromothymol blue(BB) with human serum albumin(HSA) was studied by electrochemical techniques and a sensitive method for proteins assay was developed. When BB interacted with HSA, the voltammetric peak current value of BB decreased linearly with the concentration of HSA in a range of 1.0—40.0 mg/L, and the peak potential shifted negatively. Based on the results, a sensitive assay method for proteins, such as HSA, bovine serum albumin(BSA), and egg albumin etc. was established. This method was further applied to determining the HSA in healthy human blood samples, and the results are not significantly different from those obtained by the classic Coomassie Brilliant Blue G-250 spectrophotometic method. The detecting conditions of this method were optimized and the interaction mechanism was discussed. The results show that the electrochemical parameters(formal potential E0, standard rate constant of the electrode reaction ks, parameter of kinetic nα) of BB have no obvious changes before and after the interaction, which indicate that BB can interact with HSA, forming an electrochemical non-active complex. The equilibrium constant(β_s) and the binding ratio(m) for this complex were calculated. The m is 4 and β_s is 1.41×10~(19). This method is fast, simple, highly sensitive, and has good selectivity, which can be used in clinical measurements.
Effects of vegetable oil residue after soil extraction on physical-chemical properties of sandy soil and plant growth

Vegetable oil has the ability to extract polycyclic aromatic hydrocarbons (PAHs) from contaminated sandy soil for a remediation purpose, with some of the oil remaining in the soil. Although most of the PAHs were removed, the risk of residue oil in the soil was not known. The objective of this study was to evaluate the effects of the vegetable oil residue on higher plant growth and sandy soil properties after soil extraction for a better understanding of the soil remediation. Addition of sunflower oil and column experiment were performed on a PAH contaminated soil and/or a control soil, respectively. Soils were incubated for 90 d, and soil pH was measured during the soil incubation. Higher plant growth bioassays with Avena sativa L. (oat) and Brassica rapa L. (turnip) were performed after the incubation, and then soil organic carbon contents were measured. The results show that both the nutrient amendment and the sunflower oil degradation resulted in the decrease of soil pH. When these two process worked together, their effects were counteracted due to the consumption of the nutrients and oil removal, resulting in different pH profiles. Growth of A. sativa was adversely affected by the sunflower oil, and the nutrient amendments stimulated the A. sativa growth significantly. B. rapa was more sensitive to the sunflower oil than A. sativa. Only 1% sunflower oil addition plus nutrient amendment stimulated B. rapa growth. All the other treatments on B. rapa inhibited its growth significantly. The degradation of the sunflower oil in the soils was proved by the soil organic carbon content.
Detection of hydroxyl radical in plasma reaction on toluene removal

A new method was introduced to detect the concentration of OH radical in dielectric barrier discharge (DBD) reaction. A film, which was impregnated with salicylic acid, was used to detect OH radical in plasma reaction at room temperature and atmospheric pressure. Salicylic acid reacts with OH radical and produces 2,5-dihydroxybenzoic acid (2,5-DHBA). Then, a high performance liquid chromatography (HPLC) was carried out to detect the concentration of 2,5-DHBA. Therefore, OH radical in nonthermal plasma reaction could be calculated. In this plasma reaction, the applied voltage was controlled at 10 kV, the initial concentration of toluene was 400 mg/m3, and the gas flow rate was 300 ml/min. It was observed that when the film was placed away from the plasma area, 2,5-DHBA could not be detected by HPLC, although the sampling time lasted for 48 h. On the other hand, when the film was placed in the plasma area and the sampling time being too long (> 4 h), the concentration of 2,5-DHBA was also below detection limit, and it could not be detected by HPLC. However, when the film was placed in the plasma reaction field with the sampling time being 3 h, the concentration of OH radical was calculated to be 10.54 × 10~(12) cm~(-3). In addition, concentration of OH radical was investigated under different humidity, such as 0.2%, 0.4%, 0.6%, 0.8%, and 1.0%. The results showed that the amount of OH radical stayed at order of magnitude of 1012 cm?3 and increased with the increase of humidity.
夏季青藏高原大气热源与东亚大气热源及环流的关系

利用19712000年NCEP/NCAR versionⅠ逐日再分析资料,通过倒算法计算出大气热源资料集,并采用相关分析和综合对比分析相结合的方法研究了夏季青藏高原大气热源(Q_1TP)对大范围大气热源及相应大气环流的影响,结果表明:夏季青藏高原大气热源(Q_1TP)可以在东亚大陆和西太平洋间激发出一支沿海岸向东北方向传播到达白令海峡-北极的热源波列,这支波列可能会影响到北美地区.另外,当夏季高原东部热源偏强(弱)时,南亚高压偏东(西)偏南(北),西太平洋副热带高压偏西(东)偏南(北),年际变化上南亚高压和西太平洋副热带高压在东西方向上存在"相向而行,背向而去"的关系,而高原东部的热源强迫似乎是其一种热力解释.
Al_2O_3担载Fe催化CVD法合成纳米洋葱状富勒烯

以Fe/Al_2O_3作催化剂,采用化学气相沉积法在400℃下催化裂解乙炔合成了纳米碳材料,为了去除催化剂载体和残留的催化剂颗粒,进一步将产物在60℃下于36%的浓盐酸中回流48h,并通过扫描电子显微镜、高分辨透射电子显微镜和X射线衍射仪对产物进行了表征.结果表明:在400℃下合成了直径在1550nm之间、石墨片层呈层状堆积结构的内包Fe3C的纳米洋葱状富勒烯.进一步将产物在1100℃下热处理2h,得到了具有完整清晰的石墨壳层结构的纳米洋葱状富勒烯.在此基础上,探讨了内包金属纳米洋葱状富勒烯的生长机制,认为此实验条件下内包金属纳米洋葱状富勒烯的生长遵循气-固生长机制.
树木年轮记录的青海乌兰地区近千年温度变化

过去1000a气候变化历史是评价当今气候变暖的重要背景资料.作为全球变化的敏感地区,青藏高原过去千年高分辨率气候变化重建还很少.对采集于青海省乌兰地区祁连圆柏林上限的树轮样本进行了气候响应分析,揭示了上限祁连圆柏生长主要受温度变化限制,即与上年9,11月和当年2,7月的平均温度相关显著(P<0.05),而与降水量之间不存在显著的相关关系.基于以上分析,重建了过去1000a来上年9月至当年4月平均温度的变化,转换方程的方差解释量为40.8%.重建结果显示,20世纪是过去千年中最暖的百年,20世纪90年代是最暖的10a.重建与邻近地区的树轮、湖泊沉积记录的温度变化具有较好的一致性,表明该重建是可靠的.与北半球千年温度变化对比表明,中世纪暖期时该地区的气候变化存在明显的区域特殊性,最近400a来,该地区对北半球气候变化有较好的响应.
GRAPES新一代全球/区域多尺度统一数值预报模式总体设计研究

新一代全球/区域多尺度统一的同化与数值预报系统(global/regional assimilation and prediction system,缩写为GRAPES)已在中国气象局研究建立.该系统的核心技术包括:资料变分同化;半隐式-半拉格朗日差分方案和全可压/非静力平衡动力框架;可自由组合的、优化的物理过程参数化方案;全球、区域一体化的同化与预报系统;标准化、模块化、并行化的同化与模式程序.针对GRAPES系统的正确性、有效性,已经进行了一系列的标准测试和应用模拟试验,包括常规资料分析应用、雷达和卫星非常规资料直接分析应用试验.该系统已在国家级、区域级气象业务中心运行,在实际气象业务中发挥了重要应用.本文重点介绍数值预报模式,包括总体设计思路与策略、多尺度统一动力模式构建、物理过程参数化方案组合优化、模式程序结构设计等;同时,还通过介绍GRAPES模式的模拟试验和实际应用结果等,展示多尺度统一模式的可行性和科学性、实际应用的能力和水平.
激光等离子体尾波场加速器中光学注入方法研究进展

激光等离子体尾波场加速器(LWFA,laser wake-field accelerator)作为一种新兴的台面型电子加速器,在越来越受到广泛关注的同时,也遇到了注入电子束团的来源、电子束团的俘获、加速电子束团的控制等问题,因此迫切需要寻找满足飞秒精度且易于实现的电子注入方法.光学注入法作为一种可控的内注入法,充分利用超短超快激光脉冲间相互碰撞后能预加速电子的特点,以等离子体中的背景电子为电子源,在等离子体尾波场中实现了对电子束团的有效注入、俘获、加速,得到了低能散、小发散度、短脉宽的高质量电子束团.该文简单阐述了LWFA中电子注入所面临的困难和现有的主要注入方法,综述了光学注入法的整个发展过程及最新研究进展,并以CPI(colliding pulse injection)为例讨论了如何用哈密顿量来研究LWFA中电子的注入俘获问题,希望能对该领域的研究提供一些新的思路.
电负性概念的新拓展

电负性概念1932年由Pauling提出,它与分子中原子的极化率、软硬度、电荷分布等性质之间存在着密切的内在联系,是人们判断物质性质的重要理论依据.随着新材料的发展以及各学科之间的相互交叉与渗透,电负性如今已成为在化学、物理和材料科学等领域均具有广泛应用的基本原子参数.它的发展经历了原子电负性、离子电负性和键电负性三个阶段,其中离子电负性是考虑了原子所处具体环境的价态元素电负性,用于更精确地描述离子和化合物的各种物理化学性质;键电负性是连接原子电负性和材料性质之间的桥梁,它能帮助人们更方便、直接地建立材料的宏观性质和微观结构之间的定量关系.离子电负性和键电负性的提出是对电负性概念的重要拓展,它们在丰富和发展电负性理论的同时,在新材料设计方面发挥了重要作用.该文就电负性概念的研究进展及其在材料研究中的应用作了详细介绍.
GRAPES物理过程的优化试验及程序结构设计

新一代全球/区域多尺度通用数值分析同化与预报系统(GRAPES)按照模块化、标准化的程序结构,开发建立了插拔式可移植的区域中尺度和全球中期物理过程软件包,物理过程的完整性与国外先进的模式相当.GRAPES设计了物理过程与模式框架连接的3层结构程序界面,为物理过程的插拔使用提供了一个友好界面.通过个例数值试验,对格点暴雨现象进行了分析,改进了垂直速度计算方案,通过调整GRAPES物理过程方案的相关参数,对降水方案进行了优化;结果表明,物理过程降水方案经过改进后,基本消除了虚假的格点暴雨现象,提高了降水预报的准确率.
用年际增量方法预测华北汛期降水

建立了一个华北汛期(7～8月)降水预测的新方法:通过预测华北汛期降水的年际增量(当年的变量值减去前一年的值),进而预测华北汛期降水.通过考察与华北汛期降水年际增量相配合的年际增量的大气环流,从中确定5个关键的预测因子;然后,采用多元线性回归方法建立一个华北汛期降水年际增量的预测模型.首先预测出降水的年际增量,然后再预测华北汛期降水(将当年预测的降水年际增量值加上前一年实际的降水量值).华北汛期降水年际增量的预测模型在1965～1999年中拟合率是0.8,对华北降水距平百分率的拟合平均均方根误差是19%.利用新预测模型回报2000～2007年,对降水距平百分率的回报的平均均方根误差是21%.预测模型能再现1965～2006年华北汛期降水的下降趋势.由于目前我国汛期降水预测水平是60%～70%,华北地区的降水预测更为困难,因此,通过预测降水的年际增量,进而再预测降水率的新方法能显著地提高华北汛期降水预测水平,并具有潜在的应用意义.
中国东部春季土壤湿度的时空变化特征

利用中国气象局提供的土壤湿度观测资料和欧洲中期天气预报中心(ECMWF)的ERA-40土壤湿度再分析资料,在仔细比较分析两套资料的基础上,研究了100°E以东中国春季土壤湿度的空间分布特征及其在不同时间尺度上的变化特征,结果表明ERA-40资料能很好的再现中国东部春季土壤湿度的时空变化特征,较好地反映出了中国春季土壤存在东北和西南湿、华北和内蒙古干的地理分布及其年际变化.在整个中国东部地区,春季土壤存在不同程度上的干旱化现象;其中西南地区土壤从浅层到深层都存在一致的变干趋势,20世纪80年代后这种变干趋势变得显著;在东部中纬度地区,浅层土壤湿度具有明显的年际变化特征,没有明显的干化趋势,但深层土壤湿度从1988年以后存在较为明显的干化现象;东北地区浅层和深层土壤也存在较明显的变干趋势,其中浅层土壤在20世纪70年代初以后变干趋势减缓,而深层土壤在70年代末以后的变干趋势加剧.
城市化进程对北京地区冬季降水分布的影响

根据北京地区城市化程度将城市化进程分成两个时期:即以1980年为分界点,将1961～1980年划分为城市化慢速期,1981～2000年为城市化快速期.利用北京地区14个标准气象站40a的降水量资料.研究了城市化进程对北京地区降水分布的影响.结果表明:北京地区冬季降水分布发生了显著的、系统性的变化;城市化缓慢期,北京地区南部为降水相对较多地区北部为降水相对偏少地区;城市化快速期,相对降水量的分布正相反,南部地区变为降水相对较少地区,而北部变为降水相对偏多地区.随着城市规模的扩大,北京冬季"城市热岛"和"城市干岛"效应增强,加速了云下降水物的蒸发过程,使城区及南部地区的降水相对减少.这可能是造成北京冬季降水分布变化的重要原因之一.
Comparative analysis of mitochondrial fragments transferred to the nucleus in vertebrate

Mitochondrial DNA sequences transferred to the nucleus give rise to the so-called nuclear mitochondrial DNA (numt). In the GenBank database, 244 numts have been found in six orders of birds (Anseriformes, Columbiformes, Falconiformes, Charadriiformes, Galliformes and Passeriformes). Sequences alignment (NCBI-BLASTN) was carried out with mitochondrial and corresponding nuclear genome sequences in nine vertebrate species. The sequences with high homology were considered as numts. The number of numts ranged from 15 in chicken to 159 in chimpanzee. The sequences of numts in macaque, chimpanzee, and human spanned 100% of the entire mammalian mitochondrial genome. The reconstructed frequency of the mitochondrial gene transferred to the nucleus demonstrated that the rRNA genes had high frequencies than other mitochondrial genes. Using the RepeatMasker program, the transposable elements were detected in the flanking regions of each numt. The results showed that less than 5% of the flanking sequences were made up of repetitive elements in chicken. The GC content of 5′- and 3′-flanking regions of numts in nine species was less than 44%. The analysis of the flanking sequences provided a valuable understanding for future study on mechanism of mitochondrial gene transfer to the nucleus and the site of numt integration.
无机成因和有机成因烷烃气的鉴别

在中国有机成因气(煤成气和油型气)及无机成因烷烃气(甲烷)碳同位素系列、R/Ra以及CH_4/~3He大量分析数据的基础上,结合美国、俄罗斯、德国和澳大利亚等国家相应项次众多的分析数据,经综合对比研究,提出鉴别无机成因和有机成因烷烃气的4个指标:①无机成因甲烷碳同位素组成一般>-30‰,有机成因甲烷碳同位素组成一般<-30‰;②无机成因烷烃气具有负碳同位素系列(δ~(13)C_1>δ~(13)C_2>δ~(13)C_3>δ~(13)C_4)和甲烷碳同位素组成一般>-30‰的特征;③R/Ra>0.5和δ~(13)C_1-δ~(13)C_2>0的天然气是无机成因烷烃气;④CH_4/~3He≤10~6是无机成因烷烃气(甲烷),CH_4/~3He≥10~(11)是有机成因烷烃气.
安徽庐枞(庐江-枞阳)盆地火山岩的年代学及其意义

庐枞盆地是长江中下游地区最重要的火山岩盆地之一,发育有龙门院、砖桥、双庙和浮山4组以橄榄安粗岩系为特征的火山岩地层.通过对4组火山岩中熔岩的锆石LA-ICPMS同位素定年,得到各组火山岩形成的时间分别为:龙门院组(134.8±1.8)Ma、砖桥组(134.1±1.6)Ma、双庙组(130.5±0.8)Ma和浮山组(127.1±1.2)Ma.庐枞盆地内火山岩皆形成于早白垩世,火山岩浆活动发生的起止时间约为135～127Ma,持续时间在8～10Ma左右.包括庐枞盆地在内的长江中下游地区各火山岩盆地均不存在侏罗纪火山岩浆活动.研究结果为进一步探讨和认识长江中下游及中国东部中生代构造-岩浆-成矿作用提供了新的年代学成果.
Visible Light Induced Photodegradation and Phototoxicity of Phloxine B and Uranine

Objective To determine the visible light-induced photodegradation kinetics of two xanthene photosensitizers,phloxine B and uranine,in solution and on the surface of silica TLC plates,and to examine the phototoxicity of residues of degradation,which could provide valuable safety data on the two photosensitizers and other xanthene chemicals when applied in the environment.Methods UV-Vis absorption during photodegradation was monitored with a Unico 2102 spectrophotometer.Organic content of samples was measured with a Shimadzu TOC 4100.Phototoxicity tests were carried out using Saccharomyces cerevisiae with the methods modified from Daniels.Results When phloxine B and uranine degraded in solution,their apparent rate constant k was 0.0019 and 0.0027 min~(-1),respectively.The total organic carbon(TOC) content decreased by approximately 50% during the 8 h irradiation period,which led to a gradual decrease in phototoxicity of the residues.The photodegradation of photosensitizers on the surface of silica TLC plates was much faster than that in the solution.The apparent rate constant k and the half life of phloxine B were 0.0073 min~(-1) and 95 min,respectively.Conclusion Visible light can rapidly induce photodegradation of phloxine B and uranine.The phototoxicity of residues is also decreased.The environmental risk of applications of phloxine B and uranine is minimal.
大豆转录因子GmWRKY57B的基因克隆及功能分析

WRKY类转录调控因子在高等植物中构成一个基因超家族,它不但广泛参与了植物对非生物胁迫和生物胁迫的反应,还参与了生长发育及多种代谢途径的调控.本研究构建了一个大豆cDNA文库,采用酵母单杂交的方法,用来自AtNPR1启动子区的W-box对构建的大豆cDNA文库进行筛选,获得了GmWRKY57B基因,该基因全长1033bp,编码299个氨基酸,属于WRKY类转录因子的第Ⅲ组;酵母挽救实验及凝胶阻滞实验均表明,GmWRKY57B能够与W-box特异性结合;酵母体内的转录激活实验表明,GmWRKY57B在酵母细胞中具有转录激活功能;GmWRKY57B在大豆根、茎、叶中均有表达;GmWRKY57B基因在烟草中的过表达能够提高转基因烟草植株的抗旱性,表明GmWRKY57B基因在非生物逆境中有一定的功能.
环境污染物对人体生物有效性测定的胃肠模拟研究现状

环境污染物对人体健康产生了巨大的危害,污染物的生物利用度是人体健康风险评估中的关键因子.本文系统介绍了模拟胃肠消化系统测定污染物对人体生物有效性的实验方法、主要控制条件、影响生物有效性的因素及其在健康风险评估研究中的应用.同时对其在开展有机污染物的生物有效性及其代谢研究、Caco-2细胞在该类研究中的应用以及体外模拟方法的验证方面进行了展望.
植物油厂混凝土产生裂缝的原因及控制

混凝土是工程建设中一种广泛使用的材料。针对混凝土在施工及使用过程中经常会产生裂缝的问题,通过对混凝土结构内部应力的分析,以及施工现场的实践,对混凝土裂缝产生的原因、混凝土温度应力的控制和预防裂缝的措施以及裂缝控制中的一些误区进行了阐述。
多节段下肢动脉闭塞的治疗

下肢动脉硬化闭塞症是血管外科常见病,是导致慢性下肢缺血的主要原因,其发病率随年龄增大而增加[1]。65岁以上的男性约10%患有下肢动脉硬化闭塞症,而75岁以上则有20%的发病率[2]。北美60岁以上的高血压病人中有近25%患有慢性下肢缺血[3]。多节段(combined-segment)下肢动脉闭塞是指两个或多个节段的主干动脉的严重狭窄或阻塞,也可称为多平面(multi-level)闭塞。
命门医案使用方剂及其应用特点探讨

在“命门医案的选择标准与临床应用初探”[1]文中,笔者以明代江、江应宿父子编辑的《名医类案》(1549年),清代魏之?编辑的《续名医类案》(1770年),鲁兆麟教授等主编的《二续名医类案》[2]485和余瀛鳌、高益民教授主编的《现代名中医类案选》[3]4本医案为研究范围;命门医案选择4 标准，则以明确记载治疗命门病证如命门火衰、火不生土、邪留命门，或真（元）阴、赵（元）阳不足/亏虚等字样者为标志。
急性重度有机磷农药中毒合并严重阿托品中毒一例救治体会

1病例简介患者,女,23岁,于2000-02-23入院,T 36·5℃,BP 120/70 mm Hg(1mm Hg=0·133 kPa),R 30次/m in,P138次/m in。急性重症面容,昏迷状,瞳孔等大等圆(直径1·5 mm),双肺呼吸音粗,双肺底可闻及湿啰音,心音有力,律齐,心率138次/m in,腹软,肝脾肋下未触及,双下肢无水肿。确诊为急性重度有机磷农药中毒后,立即建立静脉通道,肌肉注射氯磷定、静脉推注阿托品1020 mg,再给予大剂量的复能剂3 d,10g/d,之后给予小剂量复能剂3 d,4 g/d。根据瞳孔的变化判断是否阿托品化,给予足量的阿托品。患者入院后不到半小时,
Hypersingular parameterized Marcinkiewicz integrals with variable kernels on Sobolev and Hardy-Sobolev spaces

Let α ≥ 0 and 0 < ρ ≤ n/2, the boundedness of hypersingular parameterized Marcinkiewicz integrals μ _(Ω, α)~ ρ with variable kernels on Sobolev spaces L α p and Hardy-Sobolev spaces H_ α~p is established.
Estimation of non-point source pollution loads under uncertain information

Many kinds of uncertainties are involved, such as random, fuzzy, grey, unascertained property and so on, in soil erosion process. To exactly predict the non-point source pollution loads, some uncertainties should be taken into consideration. Aiming at the deficiency of present blind number theory being helpless for fuzziness, a novel blind number, i.e. extended-blind number, was introduced by substituting a set of triangular fuzzy numbers (TFNs), expressed as α-cuts, for interval values in present blind number, and the expected value of extended-blind number was also brought forward by referring to the current blind number theory. On the basis of denoting the parameters of Universal Soil Loss Equation (USLE) as extended-blind parameters, a novel USLE model was established for quantitatively evaluating soil erosion loss and non-point source pollution loads. As a case, the uncertain USLE was employed for predicting the soil erosion loss and non-point source pollution loads of absorbed nitrogen and phosphorus in a district in the Hangbu-Fengle River basin, in the upstream of Chaohu Lake watershed. The results show that it is feasible in theory to extend blind number into fuzzy environment and reliable on conclusion to apply extended-blind number theory for predicting non-point source pollution loads.
Impact of labor transfer on agricultural land use conversion at rural household level based on Logit model

Since land and labor force are primary resources to be used and controlled by rural households, the allocation of labor forces will influence land uses, and further lead to land use conversion. The present study used the Binary Logit model to investigate the influence of labor force transfer, characteristics of rural households, location, and land market on agricultural land use conversion at rural household level. This study was conducted based on 329 valid questionnaires, which were obtained in Changshu, Rudong, and Tongshan counties, respectively representing the southern, middle and northern areas of Jiangsu Province. The results showed that land market participation, location, zonal difference and labor transfer had strong influences on agricultural land use conversion. The participation of land market had a strong positive effect on land use conversion, especially for the farmland converted to the fishpond. The nearer to the county seat, the more conversion of land use occurred. Particularly, the labor force transfer caused by wage employment decreased this conversion probability, while the labor transfer caused by self-employment led to more conversion; and the increasing of income from labor transfer increased the conversion. Moreover, land use conversions demonstrated zonal difference, which were more in Rudong and Changshu counties than in Tongshan County, and the factors influencing this conversion were different in the three regions.