mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Genomic analysis of indigenous goats in Southwest Asia reveals evidence of ancient adaptive introgression related to desert climate

Understanding how evolutionary pressures related to climate change have shaped the current genetic background of domestic animals is a fundamental pursuit of biology.Here,we generated wholegenome sequencing data from native goat populations in Iraq and Pakistan.Combined with previously published data on modern,ancient (Late Neolithic to Medieval periods),and wild Capra species worldwide,we explored the genetic population structure,ancestry components,and signatures of natural positive selection in native goat populations in Southwest Asia (SWA).Results revealed that the genetic structure of SWA goats was deeply influenced by gene flow from the eastern Mediterranean during the Chalcolithic period,which may reflect adaptation to gradual warming and aridity in the region.Furthermore,comparative genomic analysis revealed adaptive introgression of the KITLG locus from the Nubian ibex (C.nubiana) into African and SWA goats.The frequency of the selected allele at this locus was significantly higher among goat populations located near northeastern Africa.These results provide new insights into the genetic composition and history of goat populations in the SWA region.
An optimized protocol using Steedman's wax for high-sensitivity RNA in situ hybridization in shoot apical meristems and flower buds of cucumber

In situ mRNA hybridization (ISH) is a powerful tool for examining the spatiotemporal expression of genes in shoot apical meristems and flower buds of cucumber. The most common ISH protocol uses paraffin wax; however, embedding tissue in paraffin wax can take a long time and might result in RNA degradation and decreased signals. Here, we developed an optimized protocol to simplify the process and improve RNA sensitivity. We combined embedding tissue in low melting-point Steedman's wax with processing tissue sections in solution, as in the whole-mount ISH method in the optimized protocol. Using the optimized protocol, we examined the expression patterns of the CLAVATA3 (CLV3) and WUSCHEL (WUS) genes in shoot apical meristems and floral meristems of Cucumis sativus (cucumber) and Arabidopsis thaliana (Arabidopsis). The optimized protocol saved 4-5 days of experimental period compared with the standard ISH protocol using paraffin wax. Moreover, the optimized protocol achieved high signal sensitivity. The optimized protocol was successful for both cucumber and Arabidopsis, which indicates it might have general applicability to most plants.
Peripheral actions and direct central-local communications of melanocortin 4 receptor signaling

Melanocortin 4 receptor (MC4R),the most important monogenetic cause of human metabolic disorders,has been of great interest to many researchers in the field of energy homeostasis and public health.Because MC4R is a vital pharmaceutical target for maintaining controllable appetite and body weight for professional athletes,previous studies have mainly focused on the central,rather than the peripheral,roles of MC4R.Thus,the local expression of MC4R and its behavioral regulation remain unclear.In an attempt to shed light on different directions for future studies of MC4R signaling,we review a series of recent and important studies exploring the peripheral functions of MC4R and the direct physiological interaction between peripheral organs and central MC4R neurons in this article.
La_2O_3-promoted Ni/H-ZSM-5 catalyzed aqueous-phase guaiacol hydrodeoxygenation to cyclohexanol

Hydrodeoxygenation (HDO) of renewable lignin-derived biomass in aqueous-phase to produce high value-added products is of great significance.However,developing new catalysts with high activity and excellent stability in an aqueous phase faces considerable challenges.Rare earth doping can effectively regulate the water exchange rate constant (WERC) value of the catalyst and play an important role in promoting the hydrolysis of ether bonds.Therefore,in this paper the bimetallic supported catalyst Ni eLa_2O_3/H-ZSM-5 doped with rare earth metal La_2O_3 was prepared,and used to catalyze the conversion of the lignin model compound guaiacol to cyclohexanol in the aqueous phase.The conversion of guaiacol catalyzed by 10Ni-3La_2O_3/H-ZSM-5 reaches 100%,and the selectivity of the product cyclohexanol is 85%.A series of characterizations illustrate that the doping of La_2O_3 causes the electron transfer between La_2O_3-Ni and changes the distribution of Ni,and a strong metal carrier interaction occurs between the bimetallic Ni-La_2O_3 and H-ZSM-5.This can effectively promote the hydrolysis of the CeO ether bond in guaiacol and significantly improve the activity of the catalyst.The possible catalytic reaction mechanism of Ni-La_2O_3/H-ZSM-5 catalytic conversion of guaiacol was proposed.
Bioaccumulation, subcellular distribution and chemical forms of yttrium in rice seedling

Yttrium (Y) accumulation in soil is a serious environment problem in China. To understand the mechanisms involved in Y tolerance and detoxification in rice seedling, the bioaccumulation, subcellular distribution, and chemical forms of Y was investigated in the present study. The results show that the content of Y both in roots and shoots increases with the increasing concentration of Y, and a large amount of Y is stored in roots. Subcellular distribution of Y in rice indicates that the majority of Y is bound to cell wall. Meanwhile, various chemical forms of Y is absorbed by rice. The greatest amount of Y is extracted by 2% hydrate acetic acid (HAc) and 0.6 mol/L HCl (particularly 2% HAc), which indicates that most of Y is combined with un-dissolved phosphate and oxalate (particularly phosphate). Cluster analysis, based on Y abundance levels, reveals the relationship between Y distribution patterns and chemical forms. Our results imply that Y forming of precipitates with phosphate (and/or oxalate) and depositing in the cell wall may be a key strategy for Y detoxicity and tolerance in rice.
住院老年患者吞咽障碍与衰弱的相关性研究

目的探讨住院老年患者吞咽障碍与衰弱的关系.方法对209例65岁以上的住院老年患者采用一般资料调查表、Barthel指数、洼田饮水试验及Fried衰弱表型进行调查与评估.结果住院老年患者吞咽障碍及衰弱发生率分别为27.8%、22.0%;衰弱前期及衰弱期患者吞咽障碍发生率显著高于不衰弱患者(均P<0.0167);衰弱指标中步速减慢、疲乏患者吞咽障碍发生率显著升高(均P<0.01).结论衰弱前期和衰弱期患者易发生吞咽障碍,可把衰弱作为吞咽障碍的影响因素,对该部分人群重点评估并进行针对性干预.
类风湿关节炎的整体与局部辨证

整体与局部辨证是类风湿关节炎中医辨证论治中两种不同的视角,其中整体辨证是基础,并需要综合考虑患者的体质类型,不同病情阶段的机体状态,患者所处的自然环境、气候状况、社会环境及患者情绪状态等特殊内外环境;局部辨证是补充,主要是临床医生通过对关节病变特点临床意义的辨析进而获得确切的病情资料。梳理与分析两种辨证方法在类风湿关节炎辨证中的关系,认为局部辨证包含于整体辨证之内,二者密不可分,临证需在整体中预测局部,从局部中推断整体,二者有机结合才能保证类风湿关节炎辨证的正确性和客观性。
一例Turner综合征合并多器官自身免疫疾病及严重骨质疏松症的病例报告

Turner综合征患者可合并一种或多种自身免疫疾病,因此需常规检测相关抗体并随访观察,而对患一种或多种自身免疫疾病的患儿则需警惕Turner综合征的发生,及早行染色体核型分析明确诊断.同时,Turner综合征早期诊断以及生长激素和雌激素的早期持续替代治疗对防治骨质疏松至关重要,对于确诊较晚并且已经患有严重骨质疏松的患者,小剂量的雌激素应用仍可以获益.
内蒙古西乌旗德勒哈达早白垩世A型花岗岩形成时代:锆石U-Pb定年证据

内蒙古西乌旗德勒哈达花岗岩位于贺根山缝合带典型发育区,区内广泛分布近东西向的蛇绿岩(带)和俯冲岛弧型-碰撞型-后造山型花岗岩,而侵位于贺根山缝合带蛇绿岩之中的早白垩世后造山A型花岗岩极少报道。贺根山缝合带的后造山伸展拉张阶段起止时间,尚缺乏进一步明确的年代学证据与约束。本次调查在贺根山缝合带迪彦庙—白音布拉格蛇绿岩中,新识别出德勒哈达早白垩世后造山A2型花岗岩,为揭示贺根山缝合带后造山伸展阶段构造演化提供岩石学和年代学素材。
自噬相关蛋白ATG5调控细胞自噬和凋亡的研究进展

自噬和凋亡是真核生物中广泛存在的主动或应激代谢过程,是细胞内蛋白质的生物合成和分解代谢之间保持动态平衡的关键因素之一,平衡的破坏会造成肿瘤细胞生长和细胞死亡,因此自噬和凋亡这两种程序性细胞死亡(PCD)在维持细胞生存和发育过程中扮演着重要角色。在哺乳动物细胞中,一系列自噬相关蛋白质(ATGS)如ATG4、ATG5、 Beclin-1 (酵母ATG6同源物)和ATG12等参与到自噬和凋亡的分子调控网络过程中。本文就自噬相关蛋白质ATG5调控细胞自噬和凋亡的研究进展作一综述,为进一步研究ATG5调控细胞自噬和凋亡的分子机制奠定基础。
A SPARSE GRID STOCHASTIC COLLOCATION AND FINITE VOLUME ELEMENT METHOD FOR CONSTRAINED OPTIMAL CONTROL PROBLEM GOVERNED BY RANDOM ELLIPTIC EQUATIONS

In this paper, a hybird approximation scheme for an optimal control problem governed by an elliptic equation with random field in its coefficients is considered. The random coefficients are smooth in the physical space and depend on a large number of random variables in the probability space. The necessary and sufficient optimality conditions for the optimal control problem are obtained. The scheme is established to approximate the optimality system through the discretization by using finite volume element method for the spatial space and a sparse grid stochastic collocation method based on the Smolyak approximation for the probability space, respectively. This scheme naturally leads to the discrete solutions of an uncoupled deterministic problem. The existence and uniqueness of the discrete solutions are proved. A priori error estimates are derived for the state, the co-state and the control variables. Numerical examples are presented to illustrate our theoretical results.
手机应用程序在疾病延续护理中的应用进展

移动医疗是近年来国内外关注的热点,将手机应用程序(Application,APP)与疾病延续护理结合,标志着疾病延续护理模式的改革与转变,可提高医患双方满意度,改善疾病管理质量,促进护理资源的有效利用。该文对手机APP在慢性病、术后、产后延续护理中的应用进行综述,并总结了手机延续护理APP的管理和面临的挑战,旨在提高我国护理人员对手机延续护理APP的认知,促进其使用和研制手机延续护理APP。
Physiological response of four wolfberry (Lycium Linn.) species under drought stress

We studied gas-exchange, chlorophyll pigments, lipid peroxidation, antioxidant enzymes, and biomass partitioning responses in seedlings of four wolfberry species (Lycium chinense Mill. var. potaninii (Pojark.) A. M. Lu, Lycium chinense Mill., Lycium barbarum L., and Lycium yunnanense Kuang & A. M. Lu) under four water supply regimes. In all four species, drought affected seedlings in terms of chlorophyll content, net photosynthesis rate (P_n), transpiration rate (E),and lipid peroxidation. Drought also increased some antioxidant enzyme activities, such as peroxidase (POD), catalase (CAT), superoxide dismutase (SOD), and ascorbate peroxidase (APX). Significant changes in dry biomass partitioning also occurred in response to water stress. In particular, dry biomass of leaves and fruits decreased significantly. L. chinense Mill, and L. barbarum L. possessed greater drought tolerance and exhibited superior antioxidant processing ability and other related physiological traits compared to the other two species. L. chinense Mill. was the most tolerant to all levels of drought. In contrast, L. yunnanense Kuang & A. M. Lu was more affected by water supply and had the lowest resistance to drought stress. These findings would provide some important information regarding genetic resources for future forest tree improvement in relation to drought tolerance.
Responses of the antioxidant system to fluroxypyr in foxtail millet (Setaria italica L.) at the seedling stage

Foxtail millet (Setaria italica L.) is an important food and fodder crop in semi-arid areas. However, there are few herbicides suitable for use on weed control in field-grown foxtail millet during the post-emergence herbicides stage. The present study was conducted using four concentrations (0.5, 1,2,and 4 Lai ha~(-1)) of foliar-applied fluroxypyr, and the effect of fluroxypyr on selected metabolic and stress-related parameters in foxtail millet were assessed after 15 days. In this study, increasing concentrations decreased plant height and accumulation of chlorophylls. Our results also showed that malondialdehyde (MDA) accumulated in response to fluroxypyr application, demonstrating increased lipid peroxidation due to excessive reactive oxygen species production. In response to this oxidative stress, the activities of antioxidant enzymes were generally enhanced. Non-enzymatic antioxidant defense systems, which function in concert with antioxidant enzymes, can also protect plant cells from oxidative damage by scavenging reactive oxygen species (ROS). In conclusion, the hybrid variety (Zhangzagu) exhibited a greater tolerance to fluroxypyr than did the conventional variety Jingu 21,which might be associated with the antioxidant mechanisms of Zhangzagu hybrid millet.
5-Aminolevulinic acid alleviates herbicide-induced physiological and ultrastructural changes in Brassica napus

It is well known that application of 5-aminolevulinic acid (ALA) could promote the plant growth under abiotic stress in oilseed rape (Brassica napus L.). However, the specifics of its physiological and ultrastructural regulation under herbicide stress conditions are poorly understood. In the present study, alleviating role of ALA in B. napus was investigated under four levels of herbicide propyl 4-(2-(4,6-dimethoxypyrimidin-2-yloxy) benzylamino) benzoate (ZJ0273) (0,100,200 and 500 mg L~(-1)) with or without 1 mg L~(-1) ALA treated for 48 or 72 h. Results showed that after 48 h of herbicide stress, the growth of rape seedlings was significantly inhibited with the successive increases of the ZJ0273 concentrations from 0 to 500 mg L~(-1), but this inhibition was obviously alleviated by exogenous application of ALA. However, when treatment time prolonged to 72 h, the recovery effects of ALA could not be evaluated due to the death of plants treated with the highest concentration of ZJ0273 (500 mg L~(-1)). Further, the root oxidizability and activities of antioxidant enzymes (superoxide dismutase, peroxidase and ascorbate peroxidase) were dramatically enhanced by the application of 1 mg L~(-1) ALA under herbicide stress. Therefore, plants treated with ALA dynamically modulated their antioxidant defenses to reduce reactive oxygen species (ROS) accumulation and malondialdehyde (MDA) content induced by herbicide stress. Additionally, exogenously applied ALA improved the ultrastructure's of chloroplast, mitochondria and nucleus, and induced the production of stress proteins. Our results suggest that ALA could be considered as a potential plant growth regulator for the improvement of herbicide tolerance through alleviation of the physiological and ultrastructural changes induced by the herbicide in crop production.
Characterization of GhSERK2 and its expression associated with somatic embryogenesis and hormones level in Upland cotton

Somatic embryogenesis (SE) is one of the most important steps during regeneration of cotton, but the molecular mechanism of SE remains unclear. SOMATIC EMBRYOGENSIS RECEPTOR KINASE (SERK) gene is known to function in SE. A homolog GhSERK2 (accession number: JF430801) was cloned from Upland cotton and characterized for its functions in SE. GhSERK2 expressed in different tissues and showed higher expression level in floral organs than vegetative ones with the highest levels in ovule and anther. GhSERK2 expressed during SE with a high level at globular embryos stage. Upon treatment with indole-3-butytic acid (IBA), the transcription level of GhSERK2 was induced and promoted SE subsequently. A 2-day treatment of 2,4-dichlorophenoxyacetic acid (2,4-D) induced the expression of GhSERK2, but treatments of 2,4-D for longer periods sharply inhibited the GhSERK2 transcription level of embryogenic callus (EC). The levels of hormones, including 3-indoleacetic acid (IAA), abscisic acid (ABA), and brassinosteroid (BR), were increased in the initial calli induced from the over-expression of GhSERK2 cotton. Our results indicated that GhSERK2 expression was associated with induction of SE and closely related to hormone levels during tissue culture in Upland cotton, and the gene might play an important role in regeneration of cotton.
Betaine affects muscle lipid metabolism via regulating the fatty acid uptake and oxidation in finishing pig

Background: Betaine affects fat metabolism in animals, but the specific mechanism is still not clear. The purpose of this study was to investigate possible mechanisms of betaine in altering lipid metabolism in muscle tissue in finishing pigs. Methods: A total of 120 crossbred gilts (Landrace × Yorkshire × Duroc) with an average initial body weight of 70.1 kg were randomly allotted to three dietary treatments. The treatments included a corn-soybean meal basal diet supplemented with 0, 1250 or 2500 mg/kg betaine. The feeding experiment lasted 42 d. Results: Betaine addition to the diet significantly increased the concentration of free fatty acids (FFA) in muscle (P < 0.05). Furthermore, the levels of serum cholesterol and high-density lipoprotein cholesterol were decreased (P < 0.05) and total cholesterol content was increased in muscle (P < 0.05) of betaine fed pigs. Experiments on genes involved in fatty acid transport showed that betaine increased expression of lipoprotein lipase(LPL), fottyacid tronslocase/cluster of differentiation (FAT/CD36), fotty acid binding protein (FABP3) and fatty acid transport protein (FATP1) (P < 0.05). The abundance of fatty acid transport protein and fatty acid binding protein were also increased by betaine (P < 0.05). As for the key factors involved in fatty acid oxidation, although betaine supplementation didn't affect the level of carnitine and malonyl-CoA, betaine increased mRNA and protein abundance of carnitine palmitransferase-l(CPT1) and phosphorylated-AMPK (P < 0.05). Conclusions: The results suggested that betaine may promoted muscle fatty acid uptake via up-regulating the genes related to fatty acid transporter including FAT/CD36, FATP1 and FABP3. On the other hand, betaine activated AMPK and up-regulated genes related to fatty acid oxidation including PPARa and CPT1. The underlying mechanism regulating fatty acid metabolism in pigs supplemented with betaine is associated with the up-regulation of genes involved in fatty acid transport and fatty acid oxidation.
A method for recovery of iron, titanium, and vanadium from vanadium-bearing titanomagnetite

An innovative method for recovering valuable elements from vanadium-bearing titanomagnetite is proposed. This method involves two procedures: low-temperature roasting of vanadium-bearing titanomagnetite and water leaching of roasting slag. During the roasting process, the reduction of iron oxides to metallic iron, the sodium oxidation of vanadium oxides to water-soluble sodium vanadate, and the smelting separation of metallic iron and slag were accomplished simultaneously. Optimal roasting conditions for iron/slag separation were achieved with a mixture thickness of 42.5 mm, a roasting temperature of 1200℃, a residence time of 2 h, a molar ratio of C/O of 1.7, and a sodium carbonate addition of 70wt%, as well as with the use of anthracite as a reductant. Under the optimal conditions, 93.67% iron from the raw ore was recovered in the form of iron nugget with 95.44% iron grade. After a water leaching process, 85.61% of the vanadium from the roasting slag was leached, confirming the sodium oxidation of most of the vanadium oxides to water-soluble sodium vanadate during the roasting process. The total recoveries of iron, vanadium, and titanium were 93.67%, 72.68%, and 99.72%, respectively.
Dabrafenib, an inhibitor of RIP3 kinase-dependent necroptosis, reduces ischemic brain injury

Ischemic brain injury triggers neuronal cell death by apoptosis via caspase activation and by necroptosis through activation of the receptor-interacting protein kinases (RIPK) associated with the tumor necrosis factor-alpha (TNF-a)/death receptor. Recent evidence shows RIPK inhibitors are neuroprotective and alleviate ischemic brain injury in a number of animal models, however, most have not yet undergone clinical trials and safety in humans remains in question. Dabrafenib, originally identified as a B-raf inhibitor that is currently used to treat melanoma, was later revealed to be a potent RIPK3 inhibitor at micromolar concentrations. Here, we investigated whether Dabrafenib would show a similar neuroprotective effect in mice subjected to ischemic brain injury by photothrombosis. Dabrafenib administered intraperitoneally at 10 mg/ kg one hour after photothrombosis-induced focal ischemic injury significantly reduced infarct lesion size in C57BL6 mice the following day, accompanied by a markedly attenuated upregulation of TNF-a. However, subsequent lower doses (5 mg/kg/day) failed to sustain this neuroprotective effect after 4 days. Dabrafenib bl ocked lipopolysaccharides-induced activation of TNF-a in bone marrow-derived macrophages, suggesting that Dabrafenib may attenuate TNF-a-induced necroptotic pathway after ischemic brain injury. Since Dabrafenib is already in clinical use for the treatment of melanoma, it might be repurposed for stroke therapy.
Passively Q-switched ytterbium-doped fiber laser using the evanescent field interaction with bulk-like WTe_2 particles

The potential of bulk-like WTe_2 particles for the realization of a passive Q-switch operating at the 1 µm wavelength was investigated. The WTe_2 particles were prepared using a simple mechanical exfoliation method together with Scotch tape. By attaching bulk-like WTe_2 particles, which remained on the top of the sticky surface of a small segment of the Scotch tape, to the flat side of a side-polished fiber, a saturable absorber (SA) was readily implemented. A strong saturable absorption was then readily obtained through an evanescent field interaction with the WTe_2 particles. The modulation depth of the prepared SA was measured as ~2.18% at 1.03 µm. By incorporating the proposed SA into an all-fiberized ytterbium-doped fiber ring cavity, stable Qswitched pulses were readily achieved.
Passive Q-switching in an erbium-doped fiber laser using tungsten sulphoselenide as a saturable absorber

A highly stable Q-switched laser incorporating a mechanically exfoliated tungsten sulphoselenide (WSSe) thin sheet saturable absorber (SA) is proposed and demonstrated. The SA assembly, formed by sandwiching a thin WSSe sheet between two fiber ferrules within the erbium-doped fiber laser, is used to effectively modulate the laser cavity losses. The WSSe-based SA has a saturation intensity of ~0.006 MW/cm~2 and a modulation depth of 7.8%, giving an optimum Q-switched laser output with a maximum repetition rate of 61.81 kHz and a minimum pulse width of 2.6 µs. The laser's highest output power of 0.45 mW and highest pulse energy of 7.31 nJ are achieved at the maximum pump power of 280.5 mW. The tunability of the cavity's output at the maximum pump power is analyzed with a C-band tunable bandpass filter, giving a broad tunable range of ~40 nm, from 1530 nm to 1570 nm. The output performance of the tunable Q-switched laser correlates well with the gain spectrum of erbium-doped fibers, with the shift in the gain profile as a result of the saturated SA.
少动鞘氨醇单胞菌致脓气胸1例

少动鞘氨醇单胞菌(Sphingomonas paucimobilis)为需氧不发酵糖革兰阴性杆菌,其药敏结果与铜绿假单胞菌、不动杆菌等其他不发酵糖菌不同,目前无药物敏感试验的折点值判断标准,故在脓胸的患者,需要警惕少动鞘氨醇单胞菌感染的可能性,及时进行病原学检查和调整抗感染治疗。
Highly responsive broadband black phosphorus photodetectors

Black phosphorus (BP) is a promising material for ultrafast and broadband photodetection because of its narrow bandgap from 0.35 eV (bulk) to 1.8 eV (monolayer) and high carrier mobility. Although photodetectors based on BP with different configurations have been reported, high photosensitivity was mostly observed in the visible range. A highly efficie BP-based infrared photodetector operated in the telecom spectral range, especially at 1550 nm, has not been demonstrated. Here, we report a Schottky-type photodetector based on thin BP flakes, operating in a broad spectral range from visible (635 nm) to infrared (1550 nm). A responsivity as high as 230 A · W~(-1) was achieved at 1550 nm with a source-drain bias of 1 V. The rise time is 4.8 ms, and the fall time is 6.8 ms. Under light illumination and external bias, the Schottky barrier between the BP and metal was reduced, leading to efficient photocurrent extraction. The unprecedented performance of the BP photodetector indicates intriguing potential for sensing, imaging, and optical communication.
我国细菌耐药监测工作需要进入2.0时代

抗生素的发现和应用控制了大多数由细菌引起的感染,明显降低了与感染相关的死亡率。但细菌耐药性的出现和广泛传播为临床抗感染治疗带来极大的挑战。细菌耐药监测通过分析国家、地区和部门的细菌耐药现状,监测细菌耐药性变化,掌握耐药菌株在特定人群的分布,制订遏制耐药细菌流行播散的有效措施,为临床抗感染的经验治疗和遏制细菌耐药性蔓延提供参考依据,同时亦可帮助研究机构和制药公司有目的地开发新的抗菌药物。
不同硒浓度调节绞股蓝对硒和重金属的吸收以及主要活性成分和生物量的影响

目的研究外源硒对绞股蓝品质的影响,为绞股蓝的栽培与开发利用提供理论基础。方法调整不同的外源硒浓度,以恩施特种经济植物——绞股蓝为材料进行盆栽试验,对不同浓度硒和特定浓度重金属处理条件下绞股蓝中硒含量,铅、镉、汞、砷四种重金属含量,主要生物活性成分含量的变化规律进行研究。结果随着硒处理浓度的升高绞股蓝硒含量呈先升高后降低的规律;不同浓度硒的处理对于绞股蓝吸收重金属铅、镉、汞、砷具有不同的效应,一定浓度硒的处理对于绞股蓝吸收重金属铅、镉、汞、砷均具有显著抑制作用;硒浓度的升高对绞股蓝总皂苷含量的影响体现为先抑制,后促进,再抑制的规律;硒浓度的升高对绞股蓝生长体现出低浓度促进生长,高浓度抑制生长的规律。结论绞股蓝最佳施硒浓度为25mg/kg。
半夏泻心汤加减治疗脾胃湿热型慢性浅表性胃炎的疗效观察

目的观察半夏泻心汤治疗脾胃湿热型慢性浅表性胃炎的临床疗效。方法选取符合条件的患者70例,分为观察组36例和对照组34例。对照组口服雷尼替丁、枸橼酸铋钾,观察组在对照组基础上加用中药半夏泻心汤加减治疗。2周为1个疗程,2个疗程后观察两组患者的临床疗效、治疗前后症状积分变化、不良反应情况。结果两组治疗后各项症状积分与本组治疗前比较,差异具有统计学意义(P <0.05);治疗后观察组在胃痛、烧灼感、纳差、泛酸、嗳气等方面改善明显,临床疗效优于对照组(P <0.05)。结论半夏泻心汤加减治疗脾胃湿热型慢型浅表性胃炎有较好的疗效。