mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Insights into community-based bioassessment of environmental quality status using microphytobenthos in estuarine intertidal ecosystems

The feasibility of community-based bioassessment of environmental quality status was studied using microphytobenthos (MPB) in estuarine intertidal ecosystems. The sediment samples of MPB were collected monthly during a 1-year cycle (September 2006–August 2007) at four sampling stations in the Nakdong River Estuary, Korea. Environmental variables, such as salinity, radiation, grain size of sediment, Si(OH)4 (Si), nitrate (NO_3~–), nitrite (NO_2~–), ammonium (NH_4~+) and phosphates (PO_4~(3–)), were measured synchronously for comparison with biotic parameters. The statistical analyses were carried out for assessment the relationship between biotic and environmental parameters. The results showed that: (1) the MPB community structures were significant differences among four sampling stations; (2) spatial variation in the MPB communities were significantly correlated with environmental variables, especially the nutrient NH_4~+ in combination with salinity and grain size; (3) three species (Navicula lacustris, Pleurosigma anglulatum and Fragilaria sp. 1) were significantly correlated with nutrients and/or Si; and (4) the species richness and diversity were significantly correlated with the grain size. It is suggested that MPB communities may be used as a potentially robust bioindicator for assessing environmental quality status in estuarine intertidal ecosystems.
The effect of slight to minor biodegradation on C_6 to C_7 light hydrocarbons in crude oils: a case study from Dawanqi Oilfield in the Tarim Basin, NW China

Light hydrocarbons (LHs) are one of the main petroleum fractions in crude oils, and carry much information regarding the genetic origin and alteration of crude oils. But secondary alterations-especially biodegradation--have a significant effect on the composition of LHs in crude oils. Because most of the LHs affected in oils underwent only slight biodegradation (rank 1 on the biodegradation scale), the variation of LHs can be used to describe more the refined features of biodegradation. Here, 23 crude oils from the Dawanqi Oilfield in the Tarim Basin, NW China, eleven of which have been biodegraded to different extents, were analyzed in order to investigate the effect of slight to minor biodegradation on C_6-C_7 LHs. The study results showed that biodegradation resulted in the prior depletion of straight-chained alkanes, followed by branched alkanes. In slight and minor biodegraded oils, such biodegradation scale could not sufficiently affect C_6-C_7 cycloalkanes. For branched C_6-C_7 alkanes, generally, monomethylalkanes are biodegraded earlier than dimethylalkanes and trimethylalkanes, which indicates that branched alkanes are more resistant to biodegradation, with the increase of substituted methyl groups on parent rings. The degree of alkylation is one of the primary controlling factors on the biodegradation of C_6-C_7 LHs. There is a particular case: although 2,2,3-trimethylbutane has a relative higher alkylation degree, 2,2-dimethylpentane is more resistant to biodegradation than 2,2,3-trimethylbutane. 2,2Dimethylpentane is the most resistant to biodegradation in branched C_6-C_7 alkanes. Furthermore, the 2-methylpentane/3-methylpentane and 2-methylhexane/3-methylhexane ratios decreased steadily with increasing biodegradation, which implies that isomers of bilateral methyl groups are more prone to bacterial attack relative to mid-chain isomers. The position of the alkyls on the carbon skeleton is also one of the critical factors controlling the rate of biodegradation. With increasing biodegradation, Mango's LH parameters K1 values decrease and K2 values increase, the values of n-heptane and isoheptane decrease, and the indices of methylcyclohexane and cyclohexane increase. LH parameters should be applied cautiously for the biodegraded oils. Because biodegraded samples belong to slight or minor biodegraded oils, the values of n-heptane and isoheptane from Dawanqi Oilfield can better reflect and determine the “Biodegraded” zone. When the heptane value is 0-21 and the isoheptane value is 0-2.6,the crude oil in Dawanqi Oilfield is defined as the "Biodegraded" zone.
Tin partition behavior and implications for the Furong tin ore formation associated with peralkaline intrusive granite in Hunan Province,China

Tin deposits are often closely associated with granitic intrusions. In this study, we analyzed tin partition coefficients between different fluids and melts (D_(Sn)~(aq.fl./melt)) as well as various crystals and melts D_(Sn)~(aq.fl./melt)) (D_(Sn)~(crystal/metl)) from the Furong tin deposit associated with the Qitianling A-type granite. Our experimental results indicate that tin partition behavior is affected by the chemical compositions of fluids, melts, and minerals. Tin is prone to partitioning into the residual magma in fractional crystallization or other differential magmatic processes if the magma originated from crustal sources with high alkali content, high volatile content, and low oxygen fugacity. Highly evolved residual peralkaline granitic magma enriched in tin can lead to tin mineralization in a later stage. Furthermore, the volatiles F and C1 in the magma play important roles in tin partitioning behavior. Low F contents in the melt phase and high C1 content in the aqueous fluid phase are favorable factors for tin partitioning in the aqueous fluid phase. High C1 content in the aqueous fluid catalyzes water-rock interaction and leads to the extraction of tin from tinbearing minerals. All these findings support a hydrothermal origin for the tin deposits. In light of the geotectonic setting, petrochemical characteristics, and mineralizing physicochemical conditions of the Furong tin deposit, it is inferred that the ore-forming fluid of the Furong tin ore deposit could have derived from the Qitianling peralkaline intrusion.
Zircon U-Pb dating of Pubei granite and strontium isotope from sphalerite of the Xinhua Pb-Zn-(Ag) deposit,Yunkai Area of Guangxi Province, South China

The Yunkai Area is located at the southern South China Block and is part of the Qinzhou Bay-Hangzhou Bay Metallogenic Belt,which is a famous polymetallic mineralization belt. The Xinhua Pb-Zn-(Ag) deposit is located in the western part of Yunkai Area, with an abundance of Pubei batholiths. Zircon U-Pb geochronology of Pubei batholiths shows that crystallization age ranges from 251.9 ± 2.2 to 244.3 ± 1.8 Ma, thus belonging to Indosinian orogeny. Geochemistry and Sr isotopic compositions of the Pubei batholiths show that it is derived from the partial melting of large scale crustal melting during the stage of exhumation and uplifting of the lower-middle crust. In addition, strontium isotope of sphalerite from the Xinhua Pb-Zn-(Ag) deposit, has limited ranges in ~(87)Rb/~(86)Sr and ~(87)Sr/~(86)Sr, ranging from 0.4077 to 1.0449,and 0.718720 to 0.725245, respectively. The initial 87Sr/86Sr ratios of sphalerite ranges between 0.718720 and 0.725245, which is higher than that of upper continental crust and lower than that of the Pubei batholiths, illustrating the fluid might be derived from the mixing of Pubei pluton and upper continental crust.
Ultra-Compact Photonic Crystal Based Water Temperature Sensor

We design an ultra-compact water temperature sensor by using the photonic crystal technology on the InP substrate at the 1.55-μm wavelength window. The photonic crystal consists of rods in a hexagonal lattice and a polymethyl methacrylate (PMMA) background. By using the plane wave expansion (PWE) method, the lattice constant and radius of rods are obtained, 520 nm and 80.6nm, respectively. With a nanocavity placed in the waveguide, a resonance peak is observed at the 1.55-μm wavelength window. Any change of the water temperature inside the nanocavity results in the shift of the resonance wavelength. Our simulations show a shift of about 11 nm for a temperature change of 22.5 °C. The resonance wavelength has a linear relation with the water temperature.
Study of a Distributed Feedback Diode Laser Based Hygrometer Combined Herriot-Gas Cell and Waterless Optical Components

A distributed feedback diode laser (DFB-DL) based hygrometer combined with a long-path-length Herriot gas cell and waterless optical components was proposed and investigated. The main function of this sensor was to simultaneously improve the measurement reliability and resolution. A comparison test between a 10-cm normal transmission-type gas cell and a 3-m Herriot gas cell was carried out to demonstrate the improvement. Reliability improvement was achieved by influence suppression of water vapor inside optical components (WVOC) through combined action of the Herriot gas cell and waterless optical components. The influence of WVOC was suppressed from 726ppmv to 25ppmv using the Herriot gas cell. Moreover, combined with waterless optical components, the influence of WVOC was further suppressed to no more than 4ppmv. Resolution improvement from 11.7ppmv to 0.32 ppmv was achieved mainly due to the application of the long-path-length Herriot gas cell. The results show that the proposed sensor has a good performance and considerable potential application in gas sensing, especially when probed gas possibly permeates into optical components.
Bone marrow mesenchymal stem cell therapy in ischemic stroke: mechanisms of action and treatment optimization strategies

Animal and clinical studies have confirmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly understood. Here, we summarize the transplantation approaches, directional migration, differentiation, replacement, neural circuit reconstruction, angiogenesis, neurotrophic factor secretion, apoptosis, immunomodulation, multiple mechanisms of action, and optimization strategies for bone marrow mesenchymal stem cells in the treatment of ischemic stroke. We also explore the safety of bone marrow mesenchymal stem cell transplantation and conclude that bone marrow mesenchymal stem cell transplantation is an important direction for future treatment of cerebral ischemia. Determining the optimal timing and dose for the transplantation are important directions for future research.
The role of postsynaptic density proteins in neural degeneration and regeneration

The structure, function and plasticity of excitatory glutamatergic synapses in the brain are significantly altered by neurodevelopmental and neurodegenerative disorders (Grabrucker et al., 2011; Fourie et al., 2014; Musardo et al., 2014; Lee et al., 2015), resulting in impairments in cognition, learning, memory, motor and sensory function. Reversing these synaptic deficits is a major challenge for neuroscience, and significant research has focussed on glutamate receptors as therapeutic targets but human trials have shown little success. Recently, attention has turned to proteins localized to the postsynaptic density (PSD) of excitatory synapses, as these proteins control the trafficking and targeting of glutamate receptors at synapses. Not surprisingly, PSD proteins have been shown to be altered in human and rodent models of neurological disorders, suggesting changes in their expression during the disease process (Grabrucker et al., 2011; Fourie et al., 2014; Musardo et al., 2014; Mei et al., 2016). However, the sheer number of these proteins, each with unique splice variations and developmental expression profiles, raises the possibility that targeted expression of specific PSD protein subfamilies within defined time windows has significant therapeutic potential. Indeed rescue of normal social behaviour has recently been observed in adulthood in an autism rodent model by re-expression of SHANK3, which encodes a major PSD protein, yet rescue of anxiety and motor coordination deficits required SHANK3 re-expression earlier in development (Mei et al., 2016). Peptide disruption of PSD protein interactions with glutamate receptors is also showing promise to reduce excitotoxicity and ischaemic damage in stroke models (Zhou et al., 2015). Increasing our knowledge of the potential of these proteins in human neurons is the next important step, as this will be key to determining their true therapeutic potential for neuroregeneration.
Synergetic effects of ciliary neurotrophic factor and olfactory ensheathing cells on optic nerve reparation (complete translation)

At present, there is no effective treatment for the repair of the optic nerve after injury, or improvement of its microenvironment for regeneration. Intravitreally injected ciliary neurotrophic factor (CNTF) and olfactory ensheathing cells (OECs) promote the long-distance regrowth of severed optic nerve fibers after intracranial injury. Here, we examined the efficacy of these techniques alone and in combination, in a rat model of optic nerve injury. We injected condensed OEC suspension at the site of injury, or CNTF into the vitreous body, or both simultaneously. Retrograde tracing techniques showed that 4 weeks postoperatively, the number of surviving retinal ganglion cells and their axonal density in the optic nerve were greater in rats subjected to OEC injection only than in those receiving CNTF injection only. Furthermore, combined OEC + CNTF injection achieved better results than either monotherapy. These findings confirm that OECs are better than CNTF at protecting injured neurons in the eye, but that combined OEC and CNTF therapy is notably more effective than either treatment alone.
Atorvastatin activates autophagy and promotes neurological function recovery after spinal cord injury

Atorvastatin, a lipid-lowering medication, provides neuroprotective effects, although the precise mechanisms of action remain unclear. Our previous studies confirmed activated autophagy following spinal cord injury, which was conducive to recovery of neurological functions. We hypothesized that atorvastatin could also activate autophagy after spinal cord injury, and subsequently improve recovery of neurological functions. A rat model of spinal cord injury was established based on the Allen method. Atorvastatin (5 mg/kg) was intraperitoneally injected at 1 and 2 days after spinal cord injury. At 7 days post-injury, western blot assay, reverse transcription-polymerase chain reaction, and terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) staining results showed increased Beclin-1 and light chain 3B gene and protein expressions in the spinal cord injury + atorvastatin group. Additionally, caspase-9 and caspase-3 expression was decreased, and the number of TUNEL-positive cells was reduced. Compared with the spinal cord injury + saline group, Basso, Beattie, and Bresnahan locomotor rating scale scores significantly increased in the spinal cord injury + atorvastatin group at 14-42 days post-injury. These findings suggest that atorvastatin activated autophagy after spinal cord injury, inhibited apoptosis, and promoted recovery of neurological function.
Oligodendrocyte ablation as a tool to study demyelinating diseases

Multiple sclerosis (MS) is an autoimmune mediated neurodegenerative disease characterized by demyelination and oligodendrocyte (OL) loss in the central nervous system and accompanied by local inflammation and infiltration of peripheral immune cells. Although many risk factors and symptoms have been identified in MS, the pathology is complicated and the cause remains unknown. It is also unclear whether OL apoptosis precedes the inflammation or whether the local inflammation is the cause of OL death and demyelination. This review briefly discusses several models that have been developed to specifically ablate oligodendrocytes in an effort to separate the effects of demyelination from inflammation.
Neuroprotective properties of extracellular vesicles derived from mesenchymal stem cells

Extracellular vesicles (EVs) provide a novel mechanism of intercellular communication via the transfer of proteins, lipids, and miRNAs between cells. It is now widely accepted that cargo content of EVs depends on cell type and its physiological state. Accordingly, EVs derived from healthy cells may have a comparable therapeutic potential as cells themselves. Indeed, several studies confirmed this notion and demonstrated therapeutic potential of EVs in different clinical settings. Exosomes represent a class of EVs, that can cross blood-brain barrier (Alvarez-Erviti et al., 2011), therefore they can be delivered into the CNS using intravenous, or intranasal routes avoiding the need for neurosurgical interventions. This property makes them particularly attractive as a new tool for the neuroregenerative therapies. However, new protocols require large amounts of EVs which can be obtained only from cells expanded in vitro. In this respect human mesenchymal stem cells (MSCs) represent one of the most promising cellular sources of EVs.
Displacement-based seismic design of flat slab-shear wall buildings

Flat slab system is becoming widely popular for multistory buildings due to its several advantages. However, the performance of flat slab buildings under earthquake loading is unsatisfactory due to their vulnerability to punching shear failure. Several national design codes provide guidelines for designing flat slab system under gravity load only. Nevertheless, flat slab buildings are also being constructed in high seismicity regions. In this paper, performance of flat slab buildings of various heights, designed for gravity load alone according to code, is evaluated under earthquake loading as per ASCE/SEI 41 methodology. Continuity of slab bottom reinforcement through column cage improves the performance of flat slab buildings to some extent, but it is observed that these flat slab systems are not adequate in high seismicity areas and need additional primary lateral load resisting systems such as shear walls. A displacement-based method is proposed to proportion shear walls as primary lateral load resisting elements to ensure satisfactory performance. The methodology is validated using design examples of flat slab buildings with various heights.
Seismic safety assessment of existing masonry infill structures in Nepal

Reinforced concrete (RC) buildings in Nepal arc constructed with RC frames and masonry infill panels. These structures exhibit a highly non-linear inelastic behavior resulting from the interaction between the panels and frames. This paper presents an extensive case study of existing RC buildings in Nepal. Non-linear analyses were performed on structural models of the buildings considered as a bare frame and with masonry infill, in order to evaluate the influence of infill walls on the failure mechanisms. Five three-storey buildings with different structural configurations and detailing were selected. The effect of masonry infill panels on structural response was delineated by comparing the bare-framed response with the infill response. Seismic performance is evaluated with regard to global strength, stiffness, energy dissipation, inter-storey drift, and total deflection of the structure. A parametric analysis of structures with masonry infill is also performed. For this, the influence of different material properties is studied, namely diagonal compressive stress, modulus of elasticity and tensile stress of masonry infill panels. Study results show that masonry infill increases the global strength and stiffness of the structures; it decreases the inter-storey drift and hence the total displacement of the structure. The results quantify the influence of the infill panels on structural response and, in particular, the effect of the diagonal compressive strength of the masonry wall.
三例重度胎儿胸腔积液的宫内治疗及临床转归

本研究对郑州大学第一附属医院产科收入院的3例严重的胸腔积液胎儿进行了宫内干预,随访3个月至1年半,预后均良好。3例胎儿中,1例为右侧胸腔重度积液、左侧胸腔及腹腔少量积液的胎儿,1例为右侧重度胸腔积液伴羊水过多,1例为双侧重度胸腔积液伴羊水过多,所有患儿染色体和其他相关检查未见异常,超声也未发现其他异常。例1中胎儿右侧胸腔积液最早出现于孕17周时,孕期右侧胸腔积液量持续增加,至孕33周~(+4)前超声可见左侧胸腔积液和腹腔积液,生后胎儿外观水肿。例2和例3胎儿胸水量持续增加,并伴有羊水过多,终止妊娠时未有全身水肿。宫内行胎儿胸腔穿刺引流术有助于诊断,促胎肺成熟后、剖宫产前再次行胎儿胸腔穿刺引流术有利于出生后肺扩张和新生儿复苏,出生后经对症支持等治疗,患儿均取得满意疗效,提示宫内干预并适时结束妊娠对胸腔积液胎儿具有良好的治疗效果,可以提高新生儿存活率。
隆两优华占在会昌县种植表现及高产栽培技术

隆两优华占是袁隆平农业高科技股份有限公司和中国水稻研究所选育的杂交水稻新组合,在会昌县作一季稻、晚稻示范种植,表现产量高,适应性广,抗性强。介绍了该组合种植表现及高产栽培技术要点。
Effects of Aluminum Toxicity Induced by Acid Deposition on Pine Forest Ecosystem in Longli of Guizhou Province, Southwestern China

The effects of acid deposition on pine forest ecosystems in Longli of Guizhou Province, southwestern China are studied using indoor experiments and model simulations. Indoor experiments are designed to explore the aluminum toxicity on pine seedlings, and the long-term soil acidification model (LTSAM) and a terrestrial biogeochemistry model (CENTURY) are used to simulate the influences of acid deposition on pine forest ecosystems. The indoor experiment results of aluminum toxicity show that aluminum ions in solution limit plant growth and acid deposition enhances this effect by facilitating the release of aluminum ions from the soil. Pine seedling biomass and root elongation decrease as the aluminum concentration increases. The results of model simulations show that the soil chemistry varies significantly with different changes in acid deposition. When the acid deposition increases, the pH value in the soil solution decreases and the soil Al~(3+)' concentration increases. The increased acid deposition also has negative impacts on the forest ecosystem, i.e., decreases plant biomass, net primary productivity (NPP) and net CO_2 uptake. As a result, the soil organic carbon (SOC) decreases because of the limited supply of decomposition material. Thus acid deposition need be reduced to help protect the forest ecosystems.