mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Contrast-enhanced ultrasound evaluation of hepatic microvascular changes in liver diseases

AIM:To assess if software assisted-contrast-enhanced ultrasonography (CEUS) provides reproducible perfusion parameters of hepatic parenchyma in patients affected by chronic liver disease. METHODS:Forty patients with chronic viral liver disease, with (n = 20) or without (n = 20) cirrhosis, and 10 healthy subjects underwent CEUS and video recordings of each examination were then analysed with Esaote’s Qontrast software. CEUS dedicated software Qontrast was used to determine peak (the maximum signal intensity), time to peak (TTP), region of blood value (RBV) proportional to the area under the time-intensity curve, mean transit time (MTT) measured in seconds and region of blood flow (RBF). RESULTS:Qontrast-assisted CEUS parameters displayed high inter-observer reproducibility (k coefficients of 0.87 for MTT and 0.90 TTP). When the region of interest included a main hepatic vein, Qontrast-calculated TTP was significantly shorter in cirrhotic patients (vs non-cirrhotics and healthy subjects) (71.0 ± 11.3 s vs 82.4 ± 15.6 s, 86.3 ± 20.3 s, P < 0.05). MTTs in the patients with liver cirrhosis were significantly shorter than those of controls (111.9 ± 22.0 s vs 139.4 ± 39.8 s, P < 0.05), but there was no significant difference between the cirrhotic and non-cirrhotic groups (111.9 ± 22.0 s vs 110.3 ± 14.6 s). Peak enhancement in the patients with liver cirrhosis was also higher than that observed in controls (23.9 ± 5.9 vs 18.9 ± 7.1, P = 0.05). There were no significant intergroup differences in the RBVs and RBFs. CONCLUSION:Qontrast-assisted CEUS revealed reproducible differences in liver perfusion parameters during the development of hepatic fibrogenesis.
烟草突变体筛选与鉴定方法篇:4.烟草抗干旱突变体筛选与鉴定

烟草经甲基磺酸乙酯(EMS)诱变处理可以分离得到多种突变体,这些突变体的获得将为揭示烟草生长发育规律奠定基础。烟草突变体的筛选已成为许多重要理论问题得以解决的前体,而筛选方法是突变体筛选成败的关键。干旱是影响植物生长发育的主要环境因子之一。烟草在生长过程中,特别是从团棵期进入旺长期常常遭遇干旱,干旱已经成为影响其营养生长的重要因素。利用突变体材料筛选烟草抗旱突变体,不仅可为抗旱基因克隆及功能分析奠定基础,还对于进一步探索水分胁迫信号转导及应答干旱胁迫的分子机制具有重要的意义。
Consensus statement AIGO/SICCR diagnosis and treatment of chronic constipation and obstructed defecation(Part Ⅱ:Treatment)

The second part of the Consensus Statement of the Italian Association of Hospital Gastroenterologists and Italian Society of Colo-Rectal Surgery reports on the treatment of chronic constipation and obstructed defecation.There is no evidence that increasing fluid intake and physical activity can relieve the symptoms of chronic constipation.Patients with normal-transit constipation should increase their fibre intake through their diet or with commercial fibre.Osmotic laxatives may be effective in patients who do not respond to fibre supplements.Stimulant laxatives should be reserved for patients who do not respond to osmotic laxatives.Controlled trials have shown that serotoninergic enterokinetic agents,such as prucalopride,and prosecretory agents,such as lubiprostone,are effective in the treatment of patients with chronic constipation.Surgery is sometimes necessary.Total colectomy with ileorectostomy may be considered in patients with slow-transit constipation and inertia coli who are resistant to medical therapy and who do not have defecatory disorders,generalised motility disorders or psychological disorders.Randomised controlled trials have established the efficacy of rehabilitative treatment in dys-synergic defecation.Many surgical procedures may be used to treat obstructed defecation in patients with acquired anatomical defects,but none is considered to be the gold standard.Surgery should be reserved for selected patients with an impaired quality of life.Obstructed defecation is often associated with pelvic organ prolapse.Surgery with the placement of prostheses is replacing fascial surgery in the treatment of pelvic organ prolapse,but the efficacy and safety of such procedures have not yet been established.
老年抑郁症防治新进展

老年期(或老年)抑郁症广义指存在于老年期(≥60岁)这一特定人群的抑郁症,狭义的老年抑郁症是指首发于老年期(≥60岁)的原发性抑郁症,临床表现趋于不典型,焦虑、激越症状常见,伴有认知功能障碍和较多的躯体不适主诉。目前以抗抑郁药治疗为主,常合并改良电休克治疗(MECT)和抗焦虑药、抗精神病药和促智药等多种药物,但仅约30%的病人恢复较好,总体治疗较困难、复发率高和预后欠佳。
手术综合治疗和单纯放化疗治疗老年脊柱转移瘤的疗效

脊柱转移瘤好发于老年人,因多由远隔部位的肿瘤通过血行转移而来,所以患者病情一般比较严重,肿瘤分期多为T3N3M3。以往许多学者认为,脊柱转移瘤的患者已进入疾病晚期,且多年龄较大,不宜手术治疗,应以放疗、化疗为主。近几年随着微创技术的发展、手术器械的改进,以及流行病学观点认为脊柱转移瘤的患者一般生存期较长,若不施以手术,往往导致患者生存质量下降,因而对很多脊柱转移瘤的患者施以手术治疗,并取得较好的治疗效果。本文回顾性分析我科近6年来手术综合治疗与单纯放化疗治疗脊柱转移瘤患者的疗效。
血滞通胶囊联合小剂量辛伐他汀分散片治疗老年高脂血症患者90例

高脂血症是一种全身性疾病,指高密度脂蛋白胆固醇(HDL-C)过低或血总胆固醇(TC)或甘油三酯(TG)过高,属于老年人的常见病,临床表现比较复杂。可引起血流动力学异常和动脉粥样硬化,属于心脑血管疾病的高危因素。在我国高脂血症患者发病率呈逐年上升趋势,发病年龄也倾于年轻化,高脂血症的治疗尤其是药物治疗已经成为目前研究的重要课题。本研究采用血滞通胶囊联合小剂量辛伐他汀分散片治疗高脂血症90例,取得了满意的临床疗效。
米诺环素通过调节葡萄糖调节蛋白78的表达抑制糖尿病肾细胞凋亡

目的探讨米诺环素对糖尿病肾损害的保护及与内质网应激的关系。方法STZ腹腔注射制备糖尿病大鼠模型,分别在成模即刻和8 w后每日给予米诺环素灌胃(20 mg/kg),16 w病程结束检测肾功能。Tunel检测肾组织细胞凋亡指数,免疫组化方法观察病理学改变和GRP78蛋白在肾组织中的表达变化。结果病程持续16 w结束时,DM模型组大鼠与正常对照组相比,内生肌酐清除率(Ccr)降低,血尿素氮(BUN)、24 h尿蛋白(Upro)显著升高;米诺环素干预组Ccr增加,BUN和Upro下降,与模型组相比差异显著。正常对照组的肾组织GRP78呈弱表达,DM模型组大鼠的肾组织中GRP78蛋白表达为强阳性,DM模型组GRP78表达对正常对照组相比有显著性差异。米诺环素干预组,GRP78表达明显下降,而且半程干预组比全程干预组GRP表达下降更明显。正常对照组凋亡细胞偶见;DM模型组肾组织可见大量凋亡细胞,尤其是肾小管上皮,肾小球可见部分凋亡细胞。米诺环素干预组肾小管上皮凋亡细胞明显减少,半程干预组最低。结论米诺环素改善糖尿病肾功能可能部分通过降低肾组织过度激活的内质网应激反应,减少肾小管细胞的细胞凋亡率而实现的。
缺氧条件下心肌组织的形态学改变及缺氧诱导因子-1在心脏内的表达

目的观察缺氧条件下心肌组织的形态学改变以及缺氧诱导因子-1(HIF-1α)在心脏内的表达情况。方法将40只SD大鼠随机分为正常对照组、低氧12 h组、低氧24 h组,低氧36 h组。其中低氧12 h、低氧24 h、低氧36 h组制备体内缺氧模型。采用95%氮气+5%氧气,制备缺氧模型,缺氧时间分别为12、24、36 h,每天缺氧时间为2 h,其他时间置于空气中。所有大鼠在实验结束时均实施腹腔注射麻醉,断髓法处死,制备心肌组织石蜡切片,HE染色镜下观察心肌组织的形态学变化。SABC免疫组化法检测各组大鼠心肌细胞HIF-1α的表达情况。结果正常对照组心肌组织切片心肌细胞结构完整,核大呈圆形;低氧组大鼠的心肌细胞结构逐渐变化,心肌细胞明显肿胀,细胞间隙明显增加,核变小而不规则。免疫组化染色切片HIF-1α蛋白阳性物质定位于细胞核和细胞质,呈弥散或颗粒状。与正常对照组心肌组织HIF-1α的蛋白IOD比较,各缺氧组HIF-1α的蛋白IOD明显增加,有统计学意义(P<0.05)。结论低氧可诱导大鼠心肌组织出现破坏。HIF-1α在缺血心肌组织中高表达,可能参加了心肌缺血的代偿机制,有助于改善心肌供血。
全身应用皮质类固醇类药物对缺血性视神经病变影响的Meta分析

目的评价全身应用皮质类固醇类药物对缺血性视神经病变(ION)的治疗作用。方法收集1960~2011年全身应用皮质类固醇类药物治疗缺血性视神经病变的临床试验及研究资料,通过评价文献质量、提取有效数据,对视力、视野与缺血性视神经病变合并统计量进行定量系统评价。结果与对照组相比,全身应用皮质类固醇类药物组患者:ION视力改善合并OR:1.75,95%CI(1.22~2.51);Non-arteritic ION视力改善合并OR:2.22,95%CI(1.46~3.38);ION视野改善OR:1.93,95%CI(1.23~3.02)。与对照组相比,口服泼尼松组患者:ION视力改善合并OR:2.24,95%CI(1.47~3.42)。结论全身应用皮质类固醇类药物对非动脉炎性缺血性视神经病变、缺血性视神经病变视力的改善以及缺血性视神经病变视野的改善均有良好的控制作用。口服泼尼松对缺血性视神经病变视力的改善有良好的控制作用。
80岁以上高龄老年食管癌患者调强放射治疗的临床分析

目的分析80岁以上高龄老年食管癌患者的临床特点和调强放射治疗(IMRT)的临床价值。方法2006年1月至2010年5月收治的41例80岁以上食管癌患者,按是否接受IMRT,分为IMRT组和非IMRT组。所有患者均进行最佳的内科支持治疗(BSC),同时积极处理合并基础疾患。结果IMRT组平均治疗剂量为(65.3±3.6)Gy,全组均未发生3级以上放疗反应,近期有效率(RR)为63.2%(12/19例)。Kaplan-Meier分析表明IMRT组和非IMRT组中位生存时间为11.0个月和8.0个月,1年生存率分别为31.6%(6/19)和13.6%(3/22),3年生存率分别为15.7%(3/19)和4.5%(1/22),差异显著(χ~2=6.33,P=0.01)。结论对于80岁以上高龄老年食管癌患者,积极进行IMRT,可以提高疗效。
老年2型糖尿病肾病与甲状腺功能减退的相关性

目的了解老年2型糖尿病肾病(DN)患者甲状腺功能减退的情况。方法125例老年2型DN患者,检测甲状腺激素、空腹血糖、HbA1c、血脂四项、肝肾功能,行24 h尿微量白蛋白、动脉血管彩超检查。根据甲状腺功能水平,患者分为甲状腺功能正常组和甲状腺功能减退组。结果甲状腺功能减退者共40例(包括亚临床甲减26例和临床甲减14例),约占老年2型DN患者总数的32%。甲状腺功能减退组与甲状腺功能正常组比较,女性比例升高,空腹血糖和糖化血红蛋白降低,收缩压升高(P<0.05),总胆固醇升高(P<0.05),肾功能不全比例升高。结论老年2型DN患者甲状腺功能减退发生风险高,有必要进行甲状腺功能检查。
左卡尼汀联合促红细胞生成素治疗慢性心力衰竭合并贫血患者的疗效

目的探讨左卡尼汀联合促红细胞生成素(EPO)对慢性心衰合并贫血病人心功能的改善作用。方法将43例慢性心衰合并贫血的病人随机分为治疗组23例和对照组20例。两组均予口服地高辛、速尿、螺内酯、维生素C及铁剂常规综合治疗,对照组仅应用左卡尼汀注射液,治疗组联合应用左卡尼汀注射液及EPO,共治疗16 w。分别检测治疗前后血红蛋白、血清游离脂肪酸(FFA)、红细胞膜Na~+-K~+ATP酶的活性及左心射血分数(LVEF)的变化。结果治疗组能明显提高慢性心衰合并贫血病人的血红蛋白水平、红细胞膜Na~+-K~+ATP酶活性及LVEF值,降低血清FFA的含量(P<0.01)。结论联合应用左卡尼汀及EPO可通过降低FFA含量、升高红细胞膜Na~+-K~+ATP酶活性,在纠正贫血状态的同时进一步改善心功能。
针刺治疗PCOS:当前的实验和临床报道

多囊卵巢综合征(polycystic ovarian syndrome,PCOS)是一种生殖功能障碍与糖代谢异常并存的内分泌紊乱综合征,临床以持续无排卵、雄激素过多和胰岛素抵抗(insulin resistance,IR)为主要特征,同时还存在着远期并发症的危险,如动脉粥样硬化、高血压、高血脂、糖尿病、子宫内膜癌等。下丘脑-垂体-卵巢(hy-pothalamic-pituitary-ovarian,HPO)轴功能失调,肥胖,IR,遗传因素,卵巢局部自分泌、旁分泌异常等与PCOS的发生、发展密切相关,但确切发病机制尚不清楚。目前西医多采用改善症状、促排卵及纠正代谢障碍等治疗方法,却因此会发生药物依赖以及一系列不良反应(如肥胖、抑郁、卵泡过度刺激综合征等),而使其在临床上受到一定的限制。因此,积极探索PCOS的发病机制及寻找有效的、副反应少的替代或辅助治疗方法具有重要意义。近年来针刺作为一种特殊的治疗方法,备受国内外生殖医学工作者的关注。笔者主要从动物实验和临床报道角度阐述针刺治疗PCOS的机制。
灵芝孢子粉引起胃肠道肿瘤患者CA72-4升高3例并文献分析

灵芝孢子粉是由多孔菌科真菌灵芝加工制作的保健产品,在我国拥有很高的知名度和广泛的使用率,2002年灵芝孢子粉获美国食品和药物管理局(Food and Drug Administration,FDA)认证,成为成功进入美国市场的中药之一[1]。近年来,大量体内外实验证实灵芝孢子粉具有多种药理特性,特别对于肿瘤患者能够起到抑制肿瘤增殖与转移,促进肿瘤细胞凋亡,改善患者免疫状态,增强放化疗敏感性等作用,成为临床推荐的肿瘤辅助治疗药物之一[2,3]。目前,研究普遍认为灵芝孢子粉是一种安全、有效的药物[4],但这种安全性并未经过严格的随机对照试验证实。笔者在临床治疗中发现3例胃肠道肿瘤患者使用灵芝孢子粉导致血清肿瘤标志物糖类抗原72-4 (carbohydrate antigen 72-4,CA72-4)升高,现报道如下。
工作场所空气中十溴联苯醚的气相色谱/质谱测定法

目的建立工作场所空气中十溴联苯醚的气相色谱/质谱测定法.方法超细玻璃纤维滤膜采集工作场所空气中气溶胶态十溴联苯醚,样品经索氏抽提、固相硅胶萃取柱(SPE)净化,使用气相色谱/质谱联用仪(GC/MS)测定十溴联苯醚,以定性离子和保留时间定性,同位素内标法峰面积定量.结果该方法具有良好的回收率和精密度,在加标浓度为50、150、500 ng/ml水平的平均回收率为86.23%~93.68%,批内与批间精密度分别为1.70%~4.41%和2.98%~5.01%.方法检出限为2.5 ng/ml,最低检出浓度为3.3 ng/m~3(以采集75 L空气样品计).结论该方法适用于工作场所空气中十溴联苯醚浓度测定.
Comparison of Clinical Effects of Au-Pt Based and Ni-Cr Based Porcelain Crowns

Objective To compare the long-term clinical effects of two kinds of crowns and bridges made of porcelain fused to Au-Pt alloy and Ni-Cr alloy. Methods A total of 131 teeth (64 patients) were rehabilitated using porcelain-fused-to-metal crowns, among which 59 were rehabilitated with Au-Pt alloy metal ceramic crown and 72 with Ni-Cr alloy metal ceramic crown. The porcelain fracture, shade, marginal adaptation, gingival discoloration, and gingival status after finishing restoration and 36 months of follow-up were evaluated. Results After 36 months of restoration, porcelain fused to Au-Pt alloy crown showed better clinical effects than porcelain fused to Ni-Cr alloy crown in shade, marginal adaptation, gingival discoloration, as well as gingival status (all P<0.05). Conclusion The Au-Pt alloy ceramic crown is superior to Ni-Cr alloy ceramic crown in long-term clinical effects.
流域水污染源环境风险分类分级管理研究

为了恢复和维持流域水环境的物理完整性、化学完整性和生态完整性,在对潭江流域和辽河流域印染、造纸、电镀、制药、石化等行业企业采样监测和问卷调查的基础上,识别出了流域主要的水污染源及其环境风险,并提出了基于环境风险大小的自控污染源、监控污染源、严控污染源和特控污染源4个分级管理策略。
区域水生态承载力评价指标体系研究

在已有相关研究的指标体系和国家颁布的相关指标体系基础上,提出了区域水生态承载力评价指标体系的构建依据、构建原则、分类框架、指标选取方法和标准确定方法。根据水生态承载力的概念和内涵,以压力-状态-响应(PSR)为指标体系分类框架,采用频数统计法和理论分析法相结合的方法,将已有研究中常用的、与水生态承载力密切相关的指标筛选出来,构建了区域水生态承载力指标体系,包括58个指标,其中核心指标19个,备选指标39个。在此基础上,参考国家颁布的相关标准,选取适当的核心指标对渭河陕西段水生态承载力进行评价,并进一步计算压力指数、状态指数、响应指数和承载指数,结果显示渭河陕西段水环境系统压力较大,状态最差,响应程度较高,水环境严重超载。
白术内酯类成分及其药理作用研究进展

目的:为白术的深入研究提供参考。方法:查阅国内、外文献,对白术化学成分和药理作用研究进展进行综述。结果:白术内酯类化学成分的研究主要集中在白术内酯Ⅰ、Ⅱ、Ⅲ上,而药理作用主要涉及对胃肠运动、离体子宫、炎症、肿瘤的影响等。结论:应进一步加强白术水溶性化学成分及药理作用的研究。
阿莫西林克拉维酸钾序贯疗法治疗小儿化脓性扁桃腺炎

小儿化脓性扁桃腺炎是儿科临床常见疾病之一,以溶血性链球菌感染为多,若不及时治疗可能引起较严重的并发症。临床医师通常采用静脉输液治疗,患儿痛苦大,治疗费用高。我院2004年3月至2009年12月,应用阿莫西林克拉维酸钾静脉滴注后改为口服同一药物的序贯疗法治疗小儿化脓性扁桃腺炎,在保证疗效、减少医院内感染方面取得较满意的效果。
体外膜肺氧合用于重度气管狭窄患者气道重建术的效果

先天性气管发育异常、创伤性疤痕狭窄、气管原发性肿瘤或者气管周围肿物压迫、气管切开引起的狭窄、邻近组织放射治疗后的狭窄等,均可导致重度气管狭窄.其治疗方法有外科手术切除病变后气道重建;采用钬激光或氩气刀切除气管内肿物;气管支架植入等.由于患者重度气管狭窄,不仅清醒局部麻醉下无法耐受纤维支气管镜检查,而且在全麻诱导后存在无法建立有效气道的风险.本院对4例重度气管狭窄患者,在体外膜肺氧合(ECMO)辅助下完成气道重建术.现总结如下.
烟台四十里湾表层沉积物有机质来源及环境意义

随着沿海经济的高速发展,频繁而剧烈的人类活动已对海洋生态环境健康产生了巨大的危害。沿岸水质恶化引起的赤潮频发、养殖生物大面积死亡等现象时有发生,给社会经济造成了巨大的损失。因此,有效地评价不同人类活动对海洋的危害以及建立相应的管理措施,已经成为管理者与科学家目前面临的主要科学问题之一。已有的研究表明,海洋沉积物中的有机质记录了丰富的陆、海环境信息,可以较好地反映和评价人类活动对海洋环境的影响程度。海洋沉积物中的有机质通常分为海洋和陆地两种来源:一方面,海洋生物通过生长、繁衍及死亡分解等一系列生物过程向海洋沉积物中输送了大量的有机质;另一方面,有机质还可以通过陆地河流、降雨的自然输入过程以及污水排放等人类活动到达海洋,累积在海洋沉积物中。
小脑海绵状血管瘤12例报告

颅内海绵状血管瘤(intracranial cerebral cavernous an-giomas,ICCA)是一种中枢神经系统血管畸形,而非真性肿瘤。其是由众多薄壁血管组成的海绵状异常血管团,约占所有血管畸形的10%~15%。人群发生率约为0.4%~0.8%。ICCA好发于幕上大脑皮质下,幕下少见,小脑的ICCA更为少见。但小脑的ICCAT有其相应的临床特点,本文回顾性分析我院自2000~2011年收治并经手术病理证实小脑海绵状血管瘤12例的诊治经验,现报告如下。
Responses of Soil Acid Phosphomonoesterase Activity to Simulated Nitrogen Deposition in Three Forests of Subtropical China

Soil acid phosphomonoesterase activity (APA) plays a vital role in controlling phosphorus (P) cycling and reflecting the current degree of P limitation. Responses of soil APA to elevating nitrogen (N) deposition are important because of their potential applications in addressing the relationship between N and P in forest ecosystems. A study of responses of soil APA to simulated N deposition was conducted in three succession forests of subtropical China. The three forests include a Masson pine (Pinus massoniana) forest (MPF)-pioneer community, a coniferous and broad-leaved mixed forest (MF)-transition community and a monsoon evergreen broad-leaved forest (MEBF)-climax community. Four N treatments were designed for MEBF: control (without N added), low-N (50 kg N ha~(-1) year~(-1)), and medium-N (100 kg N ha~(-1) year~(-1)) and high-N (150 kg N ha~(-1) year~(-1)), and only three N treatments (i.e., control, low-N, medium-N) were established for MPF and MF. Results showed that soil APA was highest in MEBF, followed by MPF and MF. Soil APAs in both MPF and MF were not influenced by low-N treatments but depressed in medium-N treatments. However, soil APA in MEBF exhibited negative responses to high N additions, indicating that the environment of enhanced N depositions would reduce P supply for the mature forest ecosystem. Soil APA and its responses to N additions in subtropical forests were closely related to the succession stages in the forests.
Phosphate Solubilizing Ability and Phylogenetic Diversity of Bacteria from P-Rich Soils Around Dianchi Lake Drainage Area of China

The phylogenetic diversity of phosphate solubilizing bacteria (PSB) distributed in P-rich soils in the Dianchi Lake drainage area of China was characterized, and the tricalcium phosphate (TCP) solubilizing activities of isolated PSB were determined. Among 1328 bacteria isolated from 100 P-rich soil samples, 377 isolates (28.39% of the total) that exhibited TCP solubilization activity were taken as PSB. These PSB showed different abilities to solubilize TCP, with the concentrations of solubilized P in bacterial cultures varying from 33.48 to 69.63 mg L~(-1). A total of 123 PSB isolates, with relatively high TCP solubilization activity (> 54.00 mg L~(-1)), were submitted for restriction fragment length polymorphism (RFLP) analysis, which revealed 32 unique RFLP patterns. Based on these patterns, 62 representative isolates, one to three from each RFLP pattern, were selected for 16S rRNA sequencing. Phylogenetic analysis placed the 123 PSB into three bacterial phyla, namely Proteobacteria, Actinobacteria and Firmicutes. Members of Proteobacteria were the dominant PSB, where 107 isolates represented by 26 RFLP patterns were associated with the genera of Burkholderia, Pseudomonas, Acinetobacter, Enterobacter, Pantoea, Serratia, Klebsiella, Leclercia, Raoultella and Cedecea. Firmicutes were the subdominant group, in which 13 isolates were affliated with the genera of Bacillus and Brevibacterium. The remaining 3 isolates were identified as three species of the genus Arthrobacter. This research extends the knowledge on PSB in P-rich soils and broadens the spectrum of PSB for the development of environmentally friendly biophosphate fertilizers.
双相抑郁的药物治疗现状及新探索

对双相障碍中抑郁发作的研究尤为重要,其原因在于:①躁狂发作往往为时短暂,且现有的治疗相当有效,可使患者短时间内缓解;②抑郁发作更为常见,在双相障碍发作周期中所占的时间远远长于躁狂,且往往缺乏有效的治疗。
Growth,Cadmium and Zinc Accumulation of Ornamental Sunflower (Helianthus annuus L.) in Contaminated Soil with Different Amendments

Use of ornamental plants for phytoremediation of metal-contaminated soil is a new option. A pot experiment was carried out to assess the effect of application of amendments, i.e., swine manure, salicylic acid (SA) and potassium chloride (KCl), on the growth, uptake and translocation of cadmium (Cd) and zinc (Zn) of ornamental sunflower (Helianthus annuus L.) grown on a contaminated soil. The three amendments increased sunflower height, flower diameter, and biomass. Manure significantly decreased Cd and Zn concentrations in sunflower, and thus decreased the bioaccumulation coeffcient (BCF) of Cd and Zn. However, using of KCl markedly increased Cd concentrations in sunflower and the BCF of Cd. Additionally, both swine manure and KCl application increased Cd and Zn translocation from root to aboveground part. Swine manure and salicylic acid reduced the Cd/Zn ratios in flower of sunflower, while KCl significantly increased the Cd/Zn ratios. Correlation analysis demonstrated that the Cd/Zn ratio in the root of sunflower was affected by K/Na ratio in root and soil available potassium (K) concentration. Ornamental sunflower could be grown as an alternative plant in the Cd- and Zn-contaminated soil with KCl application to get the balance between environmental and economic interests.
Effcts of Irrigation Patterns and Nitrogen Fertilization on Rice Yield and Microbial Community Structure in Paddy Soil

Water and nitrogen (N) are considered the most important factors affecting rice production and play vital roles in regulating soil microbial biomass, activity, and community. The effects of irrigation patterns and N fertilizer levels on the soil microbial community structure and yield of paddy rice were investigated in a pot experiment. The experiment was designed with four N levels of 0 (N0), 126 (N1), 157.5 (N2), and 210 kg N ha~(-1) (N3) under two irrigation patterns of continuous water-logging irrigation (WLI) and water-controlled irrigation (WCI). Phospholipid fatty acid (PLFA) analysis was conducted to track the dynamics of soil microbial communities at tillering, grain-filling, and maturity stages. The results showed that the maximums of grain yield, above-ground biomass, and total N uptake were all obtained in the N2 treatment under WCI. Similar variations in total PLFAs, as well as bacterial and fungal PLFAs, were found, with an increase from the tillering to the grain-filling stage and a decrease at the maturity stage except for actinomycetic PLFAs, which decreased continuously from the tillering to the maturity stage. A shift in composition of the microbial community at different stages of the plant growth was indicated by principal component analysis (PCA), in which the samples at the vegetative stage (tillering stage) were separated from those at the reproductive stage (grain-filling and maturity stages). Soil microbial biomass, measured as total PLFAs, was significantly higher under WCI than that under WLI mainly at the grain-filling stage, whereas the fungal PLFAs detected under WCI were significantly higher than those under WLI at the tillering, grain-filling, and maturity stages. The application of N fertilizer also significantly increased soil microbial biomass and the main microbial groups both under WLI and WCI conditions. The proper combination of irrigation management and N fertilizer level in this study was the N2 (157.5 kg N ha~(-1)) treatment under the water-controlled irrigation pattern.
心脏肿瘤的临床特点及外科诊治方法

目的探讨心脏肿瘤的发病特点及外科诊断治疗方法。方法回顾性分析93例心脏肿瘤患者的临床资料。结果本组93例心脏肿瘤患者中,良性肿瘤明显多于恶性,黏液瘤占88.2%;各年龄段均有发病,51~60岁为高发段;良性心脏肿瘤患病率男∶女为1:1.91;黏液瘤多附于房间隔,其中左侧为主。心脏原发恶性肿瘤多起源于右房游离壁。本组手术治疗生存率为93.5%。黏液瘤复发率为3.9%,恶性肿瘤患者中位生存时间为9.8个月。结论女性心脏肿瘤发病率高于男性,多位于心房,良性黏液瘤为主。心脏超声CT诊断准确率高,手术摘除是良恶性心脏肿瘤的唯一有效治疗方法,其预后取决于肿瘤的病理类型及侵及范围。
Gamma-ray shielding properties of concrete with different percentages of lead

In this work,concrete with different percentage leads was used to study gamma-ray shielding properties. The gamma-rays from ~(137)Cs and ~(60)Co sources were detected by Nal(Tl) detector and analyzed by multi-analyzer. Linear attenuation coefficients and compressive strength(kg/cm~2) of concrete specimens were conducted.Results show that the concrete at the 90% weight ratio of lead to cement can be suitable for shielding gamma-ray.
自动化药品管理柜对护士工作模式改变的分析

目的探讨自动化药品管理柜对我院护士工作带来的影响。方法通过对护士进行问卷调查的形式,结合自动化药品管理柜在我院的使用情况,对工作模式进行分析比较。结果该设备的使用提高了护士的工作效率,保证了患者用药的安全性和及时性。结论自动化药品管理柜在病房的使用,改变了护士的传统工作模式并使患者受益。
Synthesis and co-luminescence properties of Tb~(3+)-methacrylic acid-1,10-phenanthroline complexes doped with Eu~(3+)

A series of rare earth complexes Tb_(1-x)Eu_x(MAA)_3phen(x=0.00, 0.01, 0.03, 0.05, 0.07, 0.09, 0.10, 0.30, and 0.50) were synthesized with MAA as the first ligand and phen as the second ligand. The complexes were characterized by means of FT-IR, thermogravimetry-differential scanning calorimetry (TG-DSC), XRD, UV absorption spectra, and photoluminescence spectra (PL). The results show that the luminescence intensity of Eu~(3+)increases as Tb~(3+) transfer the absorbed energy to Eu~(3+) in the complexes. The emission of Tb~(3+) at 545 nm is observed and increasing with x decreasing. When x=0.01, the luminescence intensity reaches the maximum value, and the emission intensity of Tb~(3+) at 545 nm and Eu~(3+) at 614 nm are almost equal. It realizes the co-luminescence of Eu~(3+) and Tb~(3+). We can obtain complexes with different colors by adjusting the ratio of Eu~(3+) to Tb~(3+).
Optimization of heat shield for single silicon crystal growth by using numerical simulation

In integrated circuit-grade single silicon Czochralski growth, the position and material of heat shield are main parameters affecting the heat exchange and crystal growth condition. By optimizing the above parameters, we attempted to increase the growth rate and crystal quality. Numerical simulation proved to verify the results before and after optimization. Through analyses of the temperature and microdefect distribution, it is found that the optimized heat shield can further increase the pulling rate and decrease the melt/crystal interface deflection, increase the average velocity of argon flow from ~2 to ~5 m·s~(-1), which is in favor of the transportation of SiO, and obtain the low defects concentration crystal and that the average temperature along the melt-free surface is 8 °C higher than before avoiding supercooled melt effectively.
Tensile and fracture properties of Ti-62A alloy plate with different microstructures

Ti-62A alloy plates with three different types of microstructure, fully equiaxed, bimodal, and Widmanst tten, were obtained by various heat treatments to investigate the effects of microstructure on the tensile and fracture properties at room temperature. The results reveal that Widmanst tten microstructure exhibits good damage tolerance behavior considering strength, fracture toughness, and fatigue crack growth behavior, while the bimodal microstructure shows good comprehensive properties considering the plasticity synthetically. Optical microscopy (OM) and scanning electron microscopy (SEM) microstructure analyses on fracture and fatigue crack path demonstrate that the dependence of mechanical properties and fatigue crack growth behavior on microstructural feature are attributed to the α lamellae width and the α colony size.
Future projection of East China Sea temperature by dynamic downscaling of the IPCC_AR4 CCSM3 model result

Future temperature distributions of the marginal Chinese seas are studied by dynamic downscaling of global CCSM3 IPCC_AR4 scenario runs.Different forcing fields from 2080-2099 Special Report on Emissions Scenarios(SRES) B1,A1,and A2 to 1980-1999 20C3M are averaged and superimposed on CORE2 and SODA2.2.4 data to force high-resolution regional future simulations using the Regional Ocean Modeling System(ROMS).Volume transport increments in downscaling simulation support the CCSM3 result that with a weakening subtropical gyre circulation,the Kuroshio Current in the East China Sea(ECS) is possibly strengthened under the global warming scheme.This mostly relates to local wind change,whereby the summer monsoon is strengthened and winter monsoon weakened.Future temperature fluxes and their seasonal variations are larger than in the CCSM3 result.Downscaling 100 years’ temperature increments are comparable to the CCSM3,with a minimum in B1 scenario of 1.2-2.0°C and a maximum in A2 scenario of 2.5-4.5°C.More detailed temperature distributions are shown in the downscaling simulation.Larger increments are in the Bohai Sea and middle Yellow Sea,and smaller increments near the southeast coast of China,west coast of Korea,and southern ECS.There is a reduction of advective heat north of Taiwan Island and west of Tsushima in summer,and along the southern part of the Yellow Sea warm current in winter.There is enhancement of advective heat in the northern Yellow Sea in winter,related to the delicate temperature increment distribution.At 50 meter depth,the Yellow Sea cold water mass is destroyed.Our simulations suggest that in the formation season of the cold water mass,regional temperature is higher in the future and the water remains at the bottom until next summer.In summer,the mixed layer is deeper,making it much easier for the strengthened surface heat flux to penetrate to the bottom of this water.