mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
QoE-Aware Proportional Fair Scheduling for Multiuser Multiservice Wireless Networks

The effective radio resource allocation algorithms,which satisfy diversiform requirements of mobile multimedia services in wireless cellular networks,have recently attracted more and more attention.This paper proposes a service-aware scheduling algorithm,in which the Mean Opinion Score (MOS) is chosen as the unified metric of the Quality of Experience (QoE).As the network needs to provide satisfactory services to all the users,the fairness of QoE should be considered.The Proportional Fair (PF) principle is adopted to achieve the trade-off between the network performance and user fairness.Then,an integer programming problem is formed and the QoE-aware PF scheduling principle is derived by solving the relaxed problem.Simulation results show that the proposed scheduling principle can perform better in terms of user fairness than the previous principle maximizing the sum of MOS.It also outperforms the max-min scheduling principle in terms of average MOS.
Energy - Efficient Jammer Selection Approach for QoS Provisioning in Distributed Wireless Cooperative Networks

Aiming at achieving better Quality of Service (QoS) provisioning in distributed wireless cooperative networks, a novel energy efficient jammer selection approach is proposed in this paper. We employ Secrecy Capacity (SC) to characterize the security of transmission. In order to accurately describe the time-varying characteristic, related channels are modeled as Finite-State Markov Channels (FSM Cs). The remaining energy of candidate node is considered in a similar way. Accordingly, jammer selection is modeled as Restless Multi-armed Bandit problem for the sake of energy balance and security. Primal-dual heuristic and priority-index heuristic are exploited to select the optimal jammer quickly and effectively. In the simulation, numerical evaluation of SC and networks lifetime results show that the proposed approach outperforms the existing ones.
In - Network Puncturing for Delay - Efficient Rate Control of Distributed Video Coding in Wireless Video Sensor Networks

Wyner-Ziv Video Coding (WZVC) is considered as a promising video coding scheme for Wireless Video Sensor Networks (WVSNs) due to its high comp ression efficiency and error resilience functionalities, as well as its low encoding comp lexity. To achieve a good Rate-Distortion (R-D) performance, the current WZVC paradigms usually adopt an end-to-end rate control scheme in which the decoder rep eatedly requests the additional decoding data from the encoder for decoding Wyner-Ziv frames. Therefore, the waiting time of the additional decoding data is esp ecially long in multihop WVSNs. In this paper, we propose a novel progressive in-network rate control scheme for WZVC. The proposed in-network puncturing-based rate control scheme transfers the partial channel codes puncturing task from the encoder to the relay nodes. Then, the decoder can request the additional decoding data from the relay nodes instead of the encoder, and the total waiting time for decoding Wyner-Ziv frames is reduced consequently. Simulation results validate the proposed rate control scheme.
Approximate Discovery of Service Nodes by Duplicate Detection in Flows

Discovery of service nodes in flows is a challenging task,especially in large ISPs or campus networks where the amount of traffic across network is massive.We propose an effective data structure called Round-robin Buddy Bloom Filters(RBBF) to detect duplicate elements in flows.A two-stage approximate algorithm based on RBBF which can be used for detecting service nodes from NetFlow data is also given and the performance of the algorithm is analyzed.In our case,the proposed algorithm uses about 1% memory of hash table with false positive error rate less than 5%.A prototype system,which is compatible with both IPv4 and IPv6,using the proposed data structure and algorithm is introduced.Some real world case studies based on the prototype system are discussed.
Distributed Key Management Scheme against Sybil Attacks of Wireless Sensor Network

Wireless sensor network nodes(WSN nodes) have limited computing power,storage capacity,communication capabilities and energy and WSN nodes are easy to be paralyzed by Sybil attack.In order to prevent Sybil attacks,a new key distribution scheme for wireless sensor networks is presented.In this scheme,the key information and node ID are associated,and then the attacker is difficult to forge identity ID and the key information corresponding to ID can not be forged.This scheme can use low-power to resist the Sybil attack and give full play to the resource advantages of the cluster head.The computing,storage and communication is mainly undertaken by the cluster head overhead to achieve the lowest energy consumption and resist against nodes capture attack.Theoretical analysis and experimental results show that compared with the traditional scheme presented in Ref.[14],the capture rate of general nodes of cluster reduces 40%,and the capture rate of cluster heads reduces 50%.So the scheme presented in this paper can improve resilience against nodes capture attack and reduce node power consumption.
髓芯减压自体骨髓间充质干细胞移植联合高压氧治疗Ⅱ期股骨头坏死的疗效观察

股骨头缺血性坏死(avascular necrosis of the femoral head,ANFH)是由于多种因素引起的血液循环障碍,导致股骨头缺血、缺氧继而发生坏死,致残率较高,很多学者一直寻找早期ANFH的最佳治疗方法。本研究在动脉溶栓的基础上,采用髓芯减压自体骨髓间充质干细胞(mesenchymal stem cells,MSC)植入联合高压氧(hyperbaric oxygen, HBO)治疗Ⅱ期ANFH取得了较好的疗效。现报告如下。
Small intestine bleeding due to multifocal angiosarcoma

We report a case of an 84-year-old male patient with primary small intestinal angiosarcoma.The patient initially presented with anemia and melena.Consecutive endoscopy revealed no signs of upper or lower active gastrointestinal bleeding.The patient had been diagnosed 3 years previously with an aortic dilation,which was treated with a stent.Computed tomography suggested an aorto-intestinal fistula as the cause of the intestinal bleeding,leading to operative stent explantation and aortic replacement.However,an aorto-intestinal fistula was not found,and the intestinal bleeding did not arrest postoperatively.The constant need for blood transfusions made an exploratory laparotomy imperative,which showed multiple bleeding sites,predominately in the jejunal wall.A distal loop jejunostomy was conducted to contain the small intestinal bleeding and a segmental resection for histological evaluation was performed.The histological analysis revealed a lessdifferentiated tumor with characteristic CD31,cytokeratin,and vimentin expression,which led to the diagnosis of small intestinal angiosarcoma.Consequently,the infiltrated part of the jejunum was successfully resected in a subsequent operation,and adjuvant chemotherapy with paclitaxel was planned.Angiosarcoma of the small intestine is an extremely rare malignant neoplasm that presents with bleeding and high mortality.Early diagnosis and treatment are essential to improve outcome.A small intestinal angiosarcoma is a challenging diagnosis to make because of its rarity,nonspecific symptoms of altered intestinal function,nonspecific abdominal pain,severe melena,and acute abdominal signs.Therefore,a quick clinical and histological diagnosis and decisive measures including surgery and adjuvant chemotherapy should be the aim.
Does antecolic reconstruction for duodenojejunostomy improve delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy? A systematic review and meta-analysis

AIM:To evaluate whether antecolic reconstruction for duodenojejunostomy (DJ) can decrease delayed gastric emptying (DGE) rate after pylorus-preserving pancreaticoduodenectomy (PPPD) through literature review and meta-analysis. METHODS:Articles published between January 1991 and April 2012 comparing antecolic and retrocolic reconstruction for DJ after PPPD were retrieved from the databases of MEDLINE (PubMed), EMBASE, OVID and Cochrane Library Central. The primary outcome of interest was DGE. Either fixed effects model or random effects model was used to assess the pooled effect based on the heterogeneity. RESULTS:Five articles were identified for inclusion:two randomized controlled trials and three non-randomized controlled trials. The meta-analysis revealed that antecolic reconstruction for DJ after PPPD was associated with a statistically significant decrease in the incidence of DGE [odds ratio (OR), 0.06; 95% CI, 0.02-0.17; P < 0.00 001] and intra-operative blood loss [mean difference (MD), -317.68; 95% CI, -416.67 to -218.70; P < 0.00 001]. There was no significant difference between the groups of antecolic and retrocolic reconstruction in operative time (MD, 25.23; 95% CI, -14.37 to 64.83; P = 0.21), postoperative mortality, overall morbidity (OR, 0.54; 95% CI, 0.20-1.46; P = 0.22) and length of postoperative hospital stay (MD, -9.08; 95% CI, -21.28 to 3.11; P = 0.14). CONCLUSION:Antecolic reconstruction for DJ can decrease the DGE rate after PPPD.
Durability of viral response after off-treatment in HBeAg positive chronic hepatitis B

AIM:To evaluate the durability in hepatitis B e antigen (HBeAg) positive chronic hepatitis B patients who discontinued antiviral treatment. METHODS:A total of 48 HBeAg positive chronic hepatitis B patients who were administered nucleoside analogues and maintained virological response for ≥ 6 mo [hepatitis B virus (HBV) DNA < 300 copies/mL and HBeAg seroconversion] before cessation of treatment were enrolled between February 2007 and January 2010. The criteria for the cessation of the antiviral treatment were defined as follows:(1) achievement of virological response; and (2) duration of consolidation therapy (≥ 6 mo). After treatment cessation, the patients were followed up at 3-6 mo intervals. The primary endpoint was serologic and virologic recurrence rates after withdrawal of antiviral treatment. Serologic recurrence was defined as reappearance of HBeAg positivity after HBeAg seroconversion. Virologic recurrence was defined as an increase in HBV-DNA level > 104 copies/mL after HBeAg seroconversion with previously undetectable HBV-DNA level. RESULTS:During the median follow-up period of 18.2 mo (range:5.1-47.5 mo) after cessation of antiviral treatment, the cumulative serological recurrence rate was 15 % at 12 mo. The median duration between the cessation of antiviral treatment and serologic recurrence was 7.2 mo (range:1.2-10.9 mo). Of the 48 patients with HBeAg positive chronic hepatitis, 20 (41.6%) showed virological recurrence. The cumulative virologic recurrence rates at 12 mo after discontinuing the antiviral agent were 41%. The median duration between off-treatment and virologic recurrence was 7.6 mo (range:4.3-27.1 mo). The mean age of the virological recurrence group was older than that of the non-recurrence group (46.7 ± 12.1 years vs 38.8 ± 12.7 years, respectively; P = 0.022). Age (> 40 years) and the duration of consolidation treatment (≥ 15 mo) were significant predictive factors for offtreatment durability in the multivariate analysis [P = 0.049, relative risk (RR) 0.31, 95% CI (0.096-0.998) and P = 0.005, RR 11.29, 95% CI (2.054-65.12), respectively]. Patients with age (≤ 40 years) who received consolidation treatment (≥ 15 mo) significantly showed durability in HBeAg positive chronic hepatitis B patients (P = 0.014). These results suggest that additional treatment for more than 15 mo after HBeAg seroconversion in patients who are ≤ 40 years old may be beneficial in providing a sustained virological response. CONCLUSION:Our data suggest that HBeAg seroconversion is an imperfect end point in antiviral treatment. Long-term consolidation treatment (≥ 15 mo) in younger patients is important for producing better prognosis in HBeAg positive chronic hepatitis B.
Effects of telbivudine and entecavir for HBeAg-positive chronic hepatitis B: A meta-analysis

AIM:To compare the effects of telbivudine (LDT) and entecavir (ETV) in treatment of hepatitis B e antigen (HBeAg)-positive chronic hepatitis B by meta-analysis. METHODS:We conducted a literature search using PubMed, MEDLINE, EMBASE, the China National Knowledge Infrastructure, the VIP database, the Wanfang database and the Cochrane Controlled Trial Register for all relevant articles published before April 1, 2012. Randomized controlled trials (RCTs) comparing LDT with ETV for treatment of HBeAg-positive chronic hepatitis B were included. The data was analyzed with Review Manager Software 5.0. We used relative risk (RR) as an effect measure, and reported its 95% CI. Meta-analysis was performed using either a fixedeffect or random-effect model, based on the absence or presence of significant heterogeneity. Two reviewers assessed the risk of bias and extracted data indepen- dently and in duplicate. The analysis was executed using the main outcome parameters including hepatitis B virus (HBV) DNA undetectability, alanine aminotransferase (ALT) normalization, HBeAg loss, HBeAg seroconversion, drug-resistance, and adverse reactions. Meta-analysis of the included trials and subgroup analyses were conducted to examine the association between pre-specified characteristics with the therapeutic effects of the two agents. RESULTS:Thirteen eligible trials (3925 patients in total) were included and evaluated for methodological quality and heterogeneity. In various treatment durations of 4 wk, 8 wk, 12 wk, 24 wk, 36 wk, 48 wk, 52 wk, 60 wk and 72 wk, the rates of HBV DNA undetectability and ALT normalization in the two groups were similar, without statistical significance. At 4 wk and 8 wk of the treatment, no statistical differences were found in the rate of HBeAg loss between the two groups, while the rate in the LDT group was higher than in the ETV group at 12 wk, 24 wk, 48 wk and 52 wk, respectively (RR 2.28, 95% CI 1.16, 7.03, P = 0.02; RR 1.45, 95% CI 1.16, 1.82, P = 0.001; RR 1.45, 95% CI 1.11, 1.89, P = 0.006; and RR 1.86, 95% CI 1.04, 3.32, P = 0.04). At 4 wk, 8 wk, 60 wk and 72 wk of the treatment, there were no significant differences in the rate of HBeAg seroconversion between the two groups, while at 12 wk, 24 wk, 48 wk and 52 wk, the rate in the LDT group was higher than in the ETV group (RR 2.10, 95% CI 1.36, 3.24, P = 0.0008; RR 1.71, 95% CI 1.29, 2.28, P = 0.0002; RR 1.86, 95% CI 1.36, 2.54, P < 0.0001; and RR 1.87, 95% CI 1.21, 2.90, P = 0.005). The rate of drug-resistance was higher in the LDT group than in the ETV group (RR 3.76, 95% CI 1.28, 11.01, P = 0.02). In addition, no severe adverse drug reactions were observed in the two groups. And the rate of increased creatine kinase in the LDT group was higher than in the ETV group (RR 5.58, 95% CI 2.22, 13.98, P = 0.0002). CONCLUSION:LDT and ETV have similar virological and biomedical responses, and both are safe and well tolerated. However, LDT has better serological response and higher drug-resistance.
Adjuvant probiotics improve the eradication effect of triple therapy for Helicobacter pylori infection

AIM:To investigate whether the addition of probiotics can improve the eradication effect of triple therapy for Helicobacter pylori (H. pylori) infection. METHODS:This open randomized trial recruited 234 H. pylori positive gastritis patients from seven local centers. The patients were randomized to one-week standard triple therapy (omeprazole 20 mg bid, clarithromycin 500 mg bid, and amoxicillin 1000 mg bid ; OCA group, n = 79); two weeks of pre-treatment with probiotics, containing 3 × 107 Lactobacillus acidophilus per day, prior to one week of triple therapy (POCA group, n = 78); or one week of triple therapy followed by two weeks of the same probiotics (OCAP group, n = 77). Successful eradication was defined as a negative C13 or C14 urease breath test four weeks after triple therapy. Patients were asked to report associated symptoms at baseline and during follow-up, and side effects related to therapy were recorded. Data were analyzed by both intention-to-treat (ITT) and per-protocol (PP) methods. RESULTS:PP analysis involved 228 patients, 78 in the OCA, 76 in the POCA and 74 in the OCAP group. Successful eradication was observed in 171 patients; by PP analysis, the eradication rates were significantly higher (P = 0.007 each) in the POCA (62/76; 81.6%, 95% CI 72.8%-90.4%) and OCAP (61/74; 82.4%, 95% CI 73.6%-91.2%) groups than in the OCA group (48/78; 61.5%, 95% CI 50.6%-72.4%). ITT analysis also showed that eradication rates were significantly higher in the POCA (62/78; 79.5%, 95% CI 70.4%-88.6%) and OCAP (61/77; 79.2%, 95% CI 70%-88.4%) groups than in the OCA group (48/79; 60.8%, 95% CI 49.9%-71.7%), (P = 0.014 and P = 0.015). The symptom relieving rates in the POCA, OCAP and OCA groups were 85.5%, 89.2% and 87.2%, respectively. Only one of the 228 patients experienced an adverse reaction. CONCLUSION:Administration of probiotics before or after standard triple therapy may improve H. pylori eradication rates.
Checkmate to liver biopsy in chronic hepatitis C?

Liver biopsy (LB) has traditionally been considered the gold standard for pretreatment evaluation of liver fibrosis in patients with chronic hepatitis C (CHC). However, LB is an invasive procedure with several shortcomings (intra-and interobserver variability of histopathological interpretation, sampling errors, high cost) and the risk of rare but potentially life-threatening complications. In addition, LB is poorly accepted by patients and it is not suitable for repeated evaluation. Further-more, the prevalence of CHC makes LB unrealistic to be performed in all patients with this disease who are candidates for antiviral therapy. The above-mentioned drawbacks of LB have led to the development of non-invasive methods for the assessment of liver fibrosis. Several noninvasive methods, ranging from serum marker assays to advanced imaging techniques, have proved to be excellent tools for the evaluation of liver fibrosis in patients with CHC, whereas the value of LB as a gold standard for staging fibrosis prior to antiviral therapy has become questionable for clinicians. Despite significant resistance from those in favor of LB, noninvasive methods for pretreatment assessment of liver fibrosis in patients with CHC have become part of routine clinical practice. With protease inhibitors-based triple therapy already available and substantial improvement in sustained virological response, the time has come to move forward to noninvasiveness, with no risks for the patient and, thus, no need for LB in the assessment of liver fibrosis in the decision making for antiviral therapy in CHC.
半乳糖凝集素3与类风湿关节炎研究进展

目前半乳糖凝集素3与RA的研究多集中在其促进炎症损伤和骨破坏方面研究,实验样本量相对较少,但已有初步较肯定的结果。半乳糖集素3在RA发病机制中的进一步研究及与RA病情活动度的相关研究值得关注,同时半乳糖凝集素3是否有可能作为RA诊断治疗中的可靠指标及其是否能成为RA治疗的新靶点值得我们进一步探讨。
神经性会阴痛76例临床观察

神经性会阴痛多见于50岁以上的女性。患者主要症状是肛门会阴部持续、局限性疼痛。疼痛的性质多为剧烈跳痛、灼痛,并可放射至大腿内侧及阴道前方,立位或卧位可以使症状缓解。典型的女性患者表现为阴唇、会阴区或肛门直肠区痛;男性患者表现为阴茎、阴囊和会阴区痛。该症多见于盆腔脏器(如肛管、直肠)以及腰椎手术后的病人。由于病变部位在生殖神经和骶神经周围,病人常伴有泌尿系统症状(如膀胱炎、尿道炎和前列腺炎等)。也有部分病例找不到病因,这种病人多合并有抑郁症和癔症的精神症状。还有少数病人伴有紧张性头痛,查体多无阳性体征。
肌肉特异性酪氨酸激酶抗体阳性的重症肌无力合并肺部恶性肿瘤一例

对于MuSK抗体阳性MG患者的治疗,Skeie等认为,在治疗MG加重期时使用注射用人免疫球蛋白和血浆置换是有效的。Pasnoor等的研究显示53%的MuSK抗体阳性MG患者应用激索治疗有效,51%对血浆置换有效,另外20%的患者对注射用人免疫球蛋白有效。本例患者应用免疫抑制剂有效,且使用注射用人免疫球蛋白治疗后症状改善明显,故在对伴有恶性肿瘤,且不适宜行手术治疗的MuSK抗体阳性老年MG患者可尝试使用上述治疗方案。但需注意的是,在使用免疫抑制剂时应警惕肿瘤的发生。
验方"三两三"配伍经验与临床应用浅析

"三两三"是来源于民间的,经过反复临床实践的经验方。最初由宋孝志先生总结的三两三处方只有4首,与其他单验方、偏方、秘方不同,"三两三"配伍在用量上有很强的规律性,组方上有严谨的法度,同时适应症明确,部分煎服法及调摄护理体现出很强的辨病、辨证相结合的特点。其组方中罕有冷僻药材,多为临床所常用,或已经为广大中医工作者认可的对于某些病证效力突出的药物。因此其功效更多的应该在配伍方法及量效关系上进行挖掘,诚如施今墨先生强调"用药如用兵"[16]。具体而言三味"一两"的药物为主药,三味药物间如何配伍;一味"三钱"的往往有增效减毒之功,药物如何选择,如何与主药和"三分"的使引药配比;"三分"的药物更多的是药性峻猛的特效药物,是冲服还是直接入汤剂,是针对病机选择还是针对病证、症状选择,以上都是值得深入探讨和临床实践探索的问题。充分挖掘"三两三"验方配伍经验,对于提高中医临床疗效,促进中药新药开发研究中医方剂配伍与量效关系,促进成药性好的中药新药开发都有重大价值,应该引起广大中医药工作者的重视。
II型永存寰前节间动脉合并同侧椎动脉缺如一例

讨论颈-椎基底动脉在胚胎大小约3 mm左右时,出现4支暂时的吻合血管,从头侧到尾侧依次为三叉动脉、耳动脉、舌下动脉和PIA,这些吻合血管在胚胎生长到大约12~14 mm时基本消失。若某些吻合支在成人期持续存在,则称为永久性颈-椎基底动脉吻合,比较少见。
线粒体脑肌病伴高乳酸血症和卒中样发作氧摄取分数和脑血流的MRI随访研究

线粒体脑肌病伴高乳酸血症和卒中样发作(mitochondrial encephalomyopathy,lactic acidosis, and stroke-like episode,MELAS)是一种母系遗传性脑肌病,以癫痫、偏头痛、高乳酸血症、呕吐及反复的卒中样发作为特征。它主要与DNA突变有关,可以引起线粒体蛋白合成缺陷,从而造成三磷酸腺苷(ATP)生成不足。笔者通过MRI动态追踪观察了2例MELAS患者卒中样发作区域代谢的变化情况,以促进对病变发展的病理生理学机制的了解。
妊娠期干下型室间隔缺损合并主动脉右冠窦瘤破裂超声表现1例

讨论主动脉窦瘤多发生在右冠窦,而右冠窦瘤又多合并室间隔缺损。右冠窦瘤的发生部位与室间隔缺损的类型有关,窦瘤源于右冠窦左侧时,室间隔缺损常为干下型,其上缘是主-肺动脉瓣环,由于缺损和窦瘤的影响,常造成主动脉瓣环破坏,导致主动脉瓣关闭不全或脱垂。本例患者即为干下型室间隔缺损合并右冠窦瘤破裂,二者解剖结构靠近,由于窦瘤对室间隔缺损的遮盖,加上窦瘤破裂后的连续性分流易掩盖室间隔缺损的收缩期分流,室间隔缺损常易漏诊,需多切面仔细观察并结合频谱多普勒超声。窦瘤破裂前大部分遮挡缺损的室间隔,形成一个“自然封堵器”;主动脉瓣环无破坏,瓣口无反流,对患者都是一种自身性保护,患者也因此无症状而未引起重视。窦瘤破裂后因症状加重、听诊杂音出现,超声心动图检查可以明确诊断。
住院病人每日费用变化分析

目的通过对某院住院病人每日医疗费用变化分析,寻求缩短平均住院日、降低医疗费用的新途径。方法运用Powerbuilder软件和datediff函数,对2010年人均每日费用情况进行分类统计,采用SPSS17.0软件进行相关回归分析。结果该院药品费用比重控制合理,内科住院患者检查费对总费用的作用最大,外科住院患者手术费对总费用的作用最大,部分手术术前等待时间稍长。结论医院只有深化管理、推行临床路径管理,完善各项入院前检查,减少病人术前占床日,确保医疗服务质量,加快病床周转,才能有效缩短平均住院日,切实降低平均住院费用,实现患者、社会、医院多赢。
复杂抽样下的截取回归模型在医学研究中的应用

目的探讨复杂抽样下截取因变量回归模型的方差估计及在医学研究中的应用。方法模拟复杂抽样下分别从左右方向发生因变量截取的回归数据,比较不同截取比例、不同组内相关时不考虑抽样特点和考虑抽样设计后的泰勒级数法、刀切法、平衡半样本法所得到回归系数及其标准误,并给出一个医学随访实例。结果随截取比例的增加回归系数偏性增加且其标准误变大,考虑抽样特征时回归系数标准误减小,群内个体相关越小回归系数标准误也减小。结论对于抽样框完整的复杂抽样截取数据进行回归分析时,运用复杂抽样数据方差估计可提高统计推断效率。
DR3000高压发生器故障检修一例

对照维修手册,分析认为高压发生器开机过程是在得到开机信号后ATP板自检。自检通过后将主接触器K5吸合,K6不吸合,通过电阻R1给电容C1~C4快速预充电,等BUS+和BUS-的电压升到DC220 V以上后,Charge/Discharge板输信号给HT控制板J1-7脚,然后HT控制板上的Q1导通,这样K6就可以吸合,高压发生器才能正常启动。如是怀疑电阻R1电阻值太大无法快速给电容充电。测量R1电阻,电阻值在1000Ω左右,查手册得知R1正常值应该是20Ω。更换R1电阻,重新启动高压发生器,故障消失。
我国制药企业专利价值链管理模型及各环节存在的问题分析

通过构建制药企业的专利价值链管理模型,阐明了各项价值活动中的具体内容以及各项价值活动间的关系,并结合国内制药企业的实际情况,分析了企业在专利价值链管理上各项价值活动中所普遍存在的问题,为企业进行有效的专利价值链管理提供参考。
脂肪源性干细胞移植对顺铂诱导的小鼠急性肾损伤的影响

脂肪源性干细胞(ADSC)具有取材方便、对供体损伤小,以及少量组织即可获取大量干细胞等优点。我们的前期研究表明,ADSC可减轻肾小管上皮细胞结构的损伤,抑制细胞凋亡,而将低氧诱导因子(HIF-lα)转染ADSC后其作用更为明显。本研究观察ADSC移植对急性肾损伤小鼠模型肾功能、肾组织学等变化的影响。
籼型高档优质稻“星2号”选育及高产栽培技术

"星2号"一季晚稻高档优质稻品种,具有生育期适中、株叶型好、米质优、产量高等优点。全生育期124 d。平均株高110 cm左右,茎杆中粗,叶色淡绿,前期为披叶型,中、后期为直立型,叶片与主茎的角度在30°左右。一级优质稻米,各项指标均在一级以上。区试2年平均产量为7 938 kg/hm~2,比对照增产0.5%;2007~2010年的4年试种期中,平均产量6 930 kg/hm~2,比大面积杂交稻增产3%~4%。
2009年低温冷害对黑龙江省垦区水稻的影响

2009年是黑龙江省低温冷害较重的一年,依据2009年气温与历年平均气温的相互对比,明确了该年黑龙江垦区冷害发生的类型,通过不同品种、不同地点的空瘪率调查、分析明确了各个品种耐寒性的强弱及品种间的差异,并对障碍性冷害发生所引发的产量损失进行了估测。
常驻农民水污染控制意识的地域比较、影响因素及政策涵义

农民是流域面源污染的主要产生者,也是水环境恶化的直接受害者。理解农民对水污染控制的态度与需求,是实施有效流域污染控制的前提。本研究通过对江浙沪三地常驻农民的入户调查,从水质评价、水污染关注程度、水污染源治理等方面调查分析三地农民的水污染控制意识现状、地域差异和影响因素。研究结果表明:(1)三地水污染形势依然严峻;(2)农民普遍关注水污染问题,但缺乏基本的水污染知识;(3)农民普遍存在"政府依赖性",对农村污水处理的支付意愿不高。此外,农民水污染控制意识缺乏的现象普遍存在,不受地域、文化水平和年龄等因素的显著影响。由此造成的农民参与的缺失将是"十二五"期间在当地实现有效流域污染控制目标的巨大障碍。
国内外入河排污口管理经验及其对比研究

入河排污口管理是控制污染物入河总量的重要手段,也是保护水资源、改善水环境的一项重要保障措施。进行国内外入河排污口管理经验的对比,有利于完善中国的入河排污口管理制度,探索更加有效的污染物入河总量控制方法,以促进环境、经济和社会的协调发展。对比研究发现,中国入河排污口管理存在多龙治水现象,管理信息正逐步走向公开,管理以行政手段为主,监督管理成本较高,入河排污口监测体系还不完善,且侧重于排污口设置的初始管理;而美国等西方国家的管理部门较为单一,管理信息公开完全,管理以经济手段为主,监督管理的成本低,管理目标相对容易实现,还建立了较健全的监测体系,并着重实施全过程管理。最后,针对中国入河排污口管理中存在的问题,提出了打破部门分割,实施第三方监测;加强入河排污口监测能力建设和违规排污的处罚力度;加强信息公开,鼓励公众参与;建立区域间富有弹性的入河污染物总量控制制度等建议。
Robust Control for Static Loading of Electro-hydraulic Load Simulator with Friction Compensation

Load simulator is a key test equipment for aircraft actuation systems in hardware-in-the-loop-simulation. Static loading is an essential function of the load simulator and widely used in the static/dynamic stiffness test of aircraft actuation systems. The tracking performance of the static loading is studied in this paper. Firstly, the nonlinear mathematical models of the hydraulic load simulator are derived, and the feedback linearization method is employed to construct a feed-forward controller to improve the force tracking performance. Considering the effect of the friction, a LuGre model based friction compensation is synthesized, in which the unmeasurable state is estimated by a dual state observer via a controlled learning mechanism to guarantee that the estimation is bounded. The modeling errors are attenuated by a well-designed robust controller with a control accuracy measured by a design parameter. Employing the dual state observer is to capture the different effects of the unmeasured state and hence can improve the friction compensation accuracy. The tracking performance is summarized by a derived theorem. Experimental results are also obtained to verify the high performance nature of the proposed control strategy.