mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
SHEsisEpi, a GPU-enhanced genome-wide SNP-SNP interaction scanning algorithm, efficiently reveals the risk genetic epistasis in bipolar disorder

We developed a GPU-based analytical method, named as SHEsisEpi, which purely focuses on risk epistasis in a genome-wide association study (GWAS) of complex traits, excluding the contamination of marginal effects caused by single-locus association. We analyzed the Wellcome Trust Case Control Consortium's (WTCCC) GWAS data of bipolar disorder (BPD) with 500K SNPs. Our algorithm only used 27 h to finish the exhaustive scan and was more than 300 times faster than the CPU-based analysis on our system. Furthermore, by genotyping the top findin g that met our criteria (P = 5.37 × 10~(-12)) and its nearby SNP pairs in another independent 475 BPD patients and 480 normal controls from Chinese Han population, we validated these findings, related with t.Aro gene pairs, conferring risk (a = 0.05) to BPD. Binary files and source codes of our program can be downloaded at http://analysis.bio-x.cn from the main menu of SHE-SIS
弘扬科学道德 完善科学基金监督体系

2009年, 在党组领导下, 监督委员会紧紧围绕科学基金中心工作, 大力倡导严谨求实的优良学风, 维护科学道德, 弘扬科学精神, 在加强过程监督、遏制不端行为、推进建章立制、开展宣传教育4个方面进行了卓有成效的探索, 做了大量的具体工作
为婴儿着想,进一步支持妊娠期甲状腺功能筛查

甲状腺激素异常,尤其是甲状腺功能减退(甲减)在育龄期妇女中很常见,其很容易通过测定血清TSH来进行甄别.一旦发现,给予左旋甲状腺素治疗足以安全地将其控制且花费甚微.但若未及时治疗,一些调查证实,将对妊娠和(或)胎儿产生有害影响.上述范例带来一个每年影响400万美国女性的热点话题,简单而又有争议:准备怀孕和刚刚怀孕的妇女是否需要筛查甲状腺疾病?
新矿物(2007.1~2007.12)

本文以表格的形式列举了经国际矿物学协会(IMA)新矿物与矿物命名委员会(CNMNC)批准、并于2007年度正式发表的新矿物共25种. 其中硅酸盐7种,磷酸盐2种,硒酸盐1种,硫酸盐2种,碳酸盐2种,钨酸盐1种,硼酸盐2种,砷化物1种,硫盐5种,氢氧化物2种. 文中表格依次列出了矿物的中外文名称及化学式、晶系及晶胞参数、主要粉晶数据、物理性质、光学性质、产状及共生(伴生)组合等
原油中转库含油污水处理厂设计

某公司有原油中转库若干, 中转油库的含油污水来源为清罐时产生的含油污水和降雨时被污染的含油雨水, 根据油库的运行特点要建小型的含油污水处理厂. 以其中有8座10×10~4 m~3外浮顶油罐的油库为例, 介绍其设计工艺流程
代膀胱术的现状

膀胱全切除后肠代膀胱术,已经成为浸润性膀胱肿瘤及膀胱功能严重障碍等疾病的治疗金标准. 手术方式、选用肠管部位、代膀胱的形状以及输尿管移植技术都多种多样. 但目的都是原位构建一个低压、适当容量、高顺应性、控尿理想、没有残余尿的储尿囊,且能有效的保护肾功能,避免电解质紊乱、体液酸碱失衡,提高患者术后的生活质量[1]. 本文对目前国内外相关文献进行综述,对以后的临床工作进行指导. 文章中所提到的肠代膀胱术,是各种术后经尿道排尿的膀胱重建手术的统称[2]
西地那非治疗进展期特发性肺间质纤维化的随机对照试验

特发性肺问质纤维化(IPF)是一种不明原因的慢性、进展性肺疾病,发病后5年内病死率较高,目前尚无有效药物治疗.美国国家心肺血液协会IPF临床研究工作组进行了磷酸二酯酶5抑制剂西地那非治疗IPF的临床试验(STEPIPF),结果于2010年5月18日发表在新英格兰医学杂志网站(www.nejm.org)
Rab5a与胃腺癌发生和发展的关系

胃癌是最常见的恶性肿瘤之一,其发生与多种癌基因及抑癌基因异常有关.最近有研究发现一种小三磷酸乌苷(GTP)酶RabSa在胃癌中表达增加,该蛋白高表达不仅与金属基质蛋白酶-9呈正相关,且与胃癌恶性程度和转移有关[1].Rab5a可能在胃癌发生、发展中起一定作用
苯丙素甙化合物逆转耐药与谷胱甘肽S-转移酶的关系

虽然国内外学者在多药耐药(multidrug resistance, MDR)逆转剂的筛选方面研究已取得巨大进展,但逆转剂严重的不良反应仍是影响其临床应用的主要原因[1].中药因其不良反应相对较小,从中药的活性成分中筛选肿瘤逆转剂已成为目前研究的热点.苯丙素甙化合物(phenylpropanoid glycosides, PPG)是从我国西北植物红纹马先蒿中提取n],具有清除自由基、抗肿瘤的特性.但其是否具有逆转MDR作用,以及是否通过谷胱甘肽S-转移酶(glutathione S-transferases, GST)逆转MDR少见报道.本研究旨在探讨PPG逆转耐药与GST的关系
新型多组分纤维纺织品染整(二十四)

纤维素纤维/阳离子染料可染涤纶(CDP)纺织品的染色方法类似于腈纶/纤维素纤维纺织品, 可采用直接/阳离子染料一浴一步法、活性/阳离子染料一浴二步法、活性或还原/阳离子染料二浴法染色. 如果做留白染色, 则分别用直接和活性染料染纤维素纤维, CDP纤维不染即可
综合康复疗法对脊髓损伤患者下肢肌痉挛的疗效研究

目的 观察综合康复疗法对36例脊髓损伤患者下肢肌痉挛的改善情况. 方法 根据病程将36例脊髓损伤后下肢肌痉挛患者随机分为早期组和晚期组, 全面系统康复评定后, 分别进行康复宣教与护理、物理治疗、矫形器治疗、药物治疗等综合康复疗法, 治疗前、后进行改良Ashworth量表法(MAS)评定及疗效评定. 结果 经综合康复疗法治疗后, 两组患者下肢肌痉挛均有不同程度改善(P<0.001), 且早期组疗效优于晚期组(P<0.05), 1~2级肌痉挛改善效果明显, 3级肌痉挛改善困难, 治疗效果不佳. 结论综合康复疗法能有效缓解脊髓损伤患者下肢肌痉挛, 病程越短, 且肌痉挛在2级以下疗效显著, 但对于3级肌痉挛的患者仍需考虑其他侵入性治疗
血管瘤的硬化治疗

血管瘤是一种先天性血管畸形,目前临床上对于血管瘤的治疗方法较多,但尚无十分理想的模式,既往我们对于头面部血管瘤的治疗往往会留下功能障碍或美容缺陷,效果不能让人满意.我们2008年10月到2010年2月采用聚桂醇硬化治疗血管瘤患者5例,取得了较好效果,现报告如下
沙格雷酯治疗下肢动脉硬化性闭塞症的疗效观察

下肢动脉硬化性闭塞症(arteriosclerosis obliterans, ASO)是导致患者生活质量下降,丧失肢体,甚至危及生命的一类严重疾病,其病因有高龄、高血压、高血脂、糖尿病等.药物和手术是主要的治疗方法
胸主动脉瘤的腔内治疗与截瘫并发症

在过去10年里,胸主动脉瘤腔内修复术(thoracic aortic aneurysm endovascular repair, TEVAR)由于其微创的优势,使得并发症发生率及死亡率均明显下降,已经逐步代替传统外科手术成为首选的治疗方式
土地要素对经济发展的贡献分析----以广东省为例

以广东为例, 根据统计年鉴提供的数据, 通过柯布----道格拉斯函数建立模型, 分析土地要素对经济发展的贡献, 研究结果表明, 物质资本因素对经济增长的贡献率高达63％, 劳动力对经济增长的贡献率仅为15％, 土地的经济增长贡献率较从业人口数为高达到22％. 在今后的发展中, 广东必须大力转变经济增长方式, 着力提高资源利用效率, 降低物质消耗, 加快建设节约型社会; 在其经济发展过程中, 必须注重提高劳动者素质, 大力开发人力资本
新农村建设形势下开拓农村服装市场的对策

在当前大力开展新农村建设的形势下, 从开拓农村服装市场的必要性人手, 对我国农村服装市场建设存在问题进行分析.并提出了积极培育消费市场、规模发展集约经营模式、调整生产适销产品、建立"小城镇一农村"服装销售网络等对策建议
农村"一事一议"筹资筹劳制度运行中的困境与突破----基于社会资本的视角

农村"一事一议"筹资筹劳制度在运行中存在许多困境, 诸如村民自治能力弱、"有事难议, 有议难决, 决而难行"、资金供给不足等. 从社会资本的视角对这些困境进行了分析, 并提出了培育乡村组织、强化传统社会资本、构建新型社会资本来改善该制度的运行环境以突破困境
敏感性分析在远洋渔业经济效益核算中的应用

经济效益是产业的第一驱动力, 远洋渔业也不例外. 通过总结我国远洋渔业经济效益情况, 结合实例分析, 介绍了敏感性分析方法的基本原理及其在远洋渔业经济效益核算中的应用. 通过计算分析找出各因素的敏感程度、应用不足 及相应的发展建议
狂犬病病原学及其诊断方法研究进展

狂犬病是由狂犬病病毒感染中枢神经系统而引起的一种人畜共患传染病, 该病的病原致病性主要在于其基因编码的 5种蛋白: 糖蛋白(G), 核蛋A(N), 磷酸化蛋白(P), 基质蛋白(M)和转录大蛋白(L). 狂犬病的诊断目前主要有内基氏小体检测、中和试验、免疫荧光试验、ELISA、聚合酶链式反应(PCR)、动物接种试验等多种方法, 并且能够有效地诊断该病原. 就狂犬病病原学与诊断方法进行了概述, 以期为狂犬病的早期诊断和及时防治提供参考
亚麻籽木酚素抗肿瘤作用研究进展

亚麻籽木酚素对于预防与防治乳腺癌、前列腺癌、结肠癌这一类疾病意义重大, 在临床医学应用广泛. 综述了亚麻籽木酚素的结构、代谢、生理机制、抗肿瘤应用方面的研究进展, 以期为研究亚麻籽木酚素的药理功效提供理论依据
植物营养套餐技术在农业生产中的应用

在广西、河南、河北进行了"植物营养套餐技术"示范试验. 结果表明: "植物营养套餐"施肥比常规施肥处理, 每667 m~2香蕉增产9.1％, 节本增收417.4元; 玉米增产9.4％, 节本增收40.5元; 棉花增产8.6％, 节本增收33.4元; 黄瓜增产15.8％, 节本增收921.0元: 白菜增产7.0％.节本增收232.0元
重金属对水生生物的毒害作用

就目前水体中重金属污染来源及水生生物因水体中重金属污染而造成的毒性积累效应、性状表现和生化指标的毒害研究进展进行分析, 以期为解决水体中重金属污染、水产品养殖及环境治理提供借鉴
广州地区珍珠番石榴生产技术规程

珍珠番石榴生产种植面积日益增大, 已成为番石榴产业中的主要力量. 介绍了广州地区珍珠番石榴的建园定植、幼龄树管理、结果树管理、病虫害防治及采收等方面的关键生产技术, 为南亚热带地区珍珠番石榴产业化生产提供科学合理依据
百香果山地高产栽培技术

百香果适应性广、产量高、经济效益好, 是当前山区农业发展的一个短、平、快的脱贫奔康致富项目. 介绍了百香果的主要栽培技术, 包括大棚过冬育苗、选地建园、适时种植、合理施肥、及时搭架、整枝修剪、病虫害防治、适时采收等技术
优质稻新品种丰粤占的选育

丰粤占是以丰丝占为母本、粤农占为父本杂交育成的早晚兼用型常规优质稻新品种. 该品种株型适中, 分蘖力中等, 在华南双季稻区可早、晚造兼用, 2008年1月通过广东省农作物品种审定. 介绍了丰粤占的选育过程、品种特性及高产栽培技术
Critical Biot's number for Determination of the Sensitivity of Spherical Ceramics to Thermal Shock

A critical Biot number, which determines both the sensitivity of spherical ceramics to quenching and the durations of the temperature-wave propagation and the thermal stresses in the ceramics subjected to thermal shock, is theoretically obtained. The results prove that once the Biot number of a ceramic sphere is greater than the critical number, its thermal shock failure will be such a rapid process that the failure only occurs in the initial regime of heat conduction, whereas the thermal shock failure of the ceramic sphere is uncertain in the course of heat conduction. The presented results provide a guide to the selection of the ceramics applied in the thermostructural engineering with thermal shock
Generalized multilevel current source inverter topology with self-balancing current

A generalized single-phase multilevel current source inverter (MCSI) topology with self-balancing current is proposed, which uses the duality transformation from the generalized multilevel voltage source inverter (MVSI) topology. The existing single-phase 8- and 6-switch 5-level current source inverters (CSIs) can be derived from this generalized MCSI topology. In the proposed topology, each intermediate DC-link current level can be balanced automatically without adding any external circuits; thus, a true multilevel structure is provided. Moreover, owing to the dual relationship, many research results relating to the operation, modulation, and control strategies of MVSIs can be applied directly to the MCSIs. Some simulation results are presented to verify the proposed MCSI topology
Derivation of embryonic stem cells from Brown Norway rats blastocysts

Knockout Brown Norway(BN)rat could be a useful disease model for human disorders,however,a failure to derive embryonic stem (ES)cells disturbs the further development of the model.In this study,we reported a case of successful derivation of the BN rat ES cells with the derivation efficiency comparable to that of Sprague Dawley(SD)rats.The BN rat ES cells expressed the key transcription factors,and were able to form embryonic bodies(EBs)when being differentiated in vitro.After injecting the BN rat ES cells into the SD rat blastocysts,high-contribution chimeric rats were generated and could survive to their adulthood.Our success in generating pluripotent rat ES cells will benefit the generation of the knockout rats in the future.
Contribution of myeloid-derived suppressor cells to tumor-induced immune suppression, angiogenesis, invasion and metastasis

Growing evidence suggests that myeloid-derived suppressor cells (MDSCs), which have been named "immature myeloid cells" or "myeloid suppressor cells" (MSCs), play a critical role during the progression of cancer in tumor-bearing mice and cancer patients. As their name implies, these cells are derived from bone marrow and have a tremendous potential to suppress immune responses. Recent studies indicated that these cells also have a crucial role in tumor progression. MDSCs can directly incorporate into tumor endothelium. They secret many pro-angiogenic factors as well. In addition, they play an essential role in cancer invasion and metastasis through inducing the production of matrix metalloproteinases (MMPs), chemoattractants and creating a pre-metastatic environment. Increasing evidence supports the idea that cancer stem cells (CSCs) are responsible for tumorigenesis, resistance to therapies, invasion and metastasis. Here, we hypothesize that CSCs may "hijack" MDSCs for use as alternative niche cells, leading to the maintenance of stemness and enhanced chemo- and radio-therapy resistance. The countermeasure that directly targets to MDSCs may be useful for against angiogenesis and preventing cancer from invasion and metastasis. Therefore, the study of MDSCs is important to understand tumor progression and to enhance the therapeutic efficacy against cancer.
硼替佐米治疗多发性骨髓瘤致肺损伤1例并文献复习

目的提高对硼替佐米导致肺损伤的认识, 探讨恰当的防治措施. 方法报道1例多发性骨髓瘤患者应用硼替佐米后出现严重肺损伤的症状和体征、实验室检查、胸部CT结果以及治疗和转归, 并进行相关文献复习. 结果硼替佐米导致的肺损伤多表现为发热、干咳、呼吸困难, 双肺干湿罗音, 低氧血症, 微生物学检查阴性, 胸部CT示双肺弥漫性渗出, 大剂量激素治疗多有效. 结论硼替佐米可以导致严重的肺损伤, 临床医生在用药过程中应高度警惕.
DNA replication origins, ORC/DNA interaction, and assembly of pre-replication complex in eukaryotes

Chromosomal DNA replication in eukaryotic cells is highly complicated and sophisticatedly regulated. Owing to its large size, a typical eukaryotic genome contains hundreds to tens of thousands of initiation sites called DNA replication origins where DNA synthesis takes place. Multiple initiation sites remove the constraint of a genome size because only a certain amount of DNA can be replicated from a single origin in a limited time. The activation of these multiple origins must be coordinated so that each segment of chromosomal DNA is precisely duplicated only once per cell cycle. Although DNA replication is a vital process for cell growth and its mechanism is highly conserved, recent studies also reveal significant diversity in origin structure, assembly of pre-replication complex (pre-RC) and regulation of replication initiation along evolutionary lines. The DNA replication origins in the fission yeast Schizosaccharomyces pombe are found to contain a second essential element that is bound by Sapl protein besides the essential origin recognition complexbinding site. Sapl is recently demonstrated to be a novel replication initiation protein that plays an essential role in loading the initiation protein Cdc18 to origins and thus directly participates in pre-RC formation. In this review, we summarize the recent advance in understanding how DNA replication origins are organized, how pre-RC is assembled and how DNA replication is initiated and regulated in yeast and metazoans.
数据库加密与密文查询技术研究

分析了基于文件、记录、字段的数据库加密方法和生成子密钥加密方法,介绍了生成子密钥的字段加密技术,并在此基础上,对基于密文查询的两种方法进行了深入的探讨,比较了它们的优缺点,并提出了加密数据库存在和要解决的问题。
焊接逆变电源数字控制的分析

针对传统电焊机的交流电压的频率为电网频率50Hz的工作特点,其工作效率低,焊接效果差,耗电多等缺点。本文设计了焊接逆变电源的数字控制,通过数字控制实现电焊机逆变电源输出交流电压的频率,其实现方法是通过改变单相逆变器SPWM的调制波的频率,从而改变输出交流电压的频率。通过理论分析和DSP数字控制实验验证了该控制系统的稳定性和可靠性,并能适时的改变逆变电源输出交流电压的频率,该方法能提高焊接的效率、降低能源,提高焊接质量。
基于全相位FFT的故障信号检测方法

针对机械系统中的机械故障信号检测,首次提出了一种通用的全相位FFT检测方法。全相位FFT就是自身的频谱分析功能来实现对信号相位、频率和振幅的判决,所得到的相位没有误差,振幅误差也远小于基于FFT的检测技术。通过理论分析和MATLAB仿真,全相位FFT检测得到的信号相位误差为0,频谱校正后的振幅和频率误差也非常低,表明了该方法在故障信号检测中的可行性和正确性。
Changing face of hepatic encephalopathy: Role of inflammation and oxidative stress

The face of hepatic encephalopathy (HE) is changing. This review explores how this neurocognitive disorder, which is associated with both acute and chronic liver injury, has grown to become a dynamic syndrome that spans a spectrum of neuropsychological impairment, from normal performance to coma. The central role of ammonia in the pathogenesis of HE remains incontrovertible. However, over the past 10 years, the HE community has begun to characterise the key roles of inflammation, infection, and oxidative/nitrosative stress in modulating the pathophysiological effects of ammonia on the astrocyte. This review explores the current thoughts and evidence base in this area and discusses the potential role of existing and novel therapies that might abrogate the oxidative and nitrosative stresses inflicted on the brain in patients with, or at risk of developing, HE.
Association of glypican-3 expression with growth signaling molecules in hepatocellular carcinoma

AIM:To clarify the association of glypican-3(GPC3)expression with Wnt and other growth signaling molecules in hepatocellular carcinoma(HCC). METHODS:Expression of GPC3, Wnt, matrix metalloproteinases(MMPs), sulfatase(SULF)1, SULF2, and other growth signaling molecules was analyzed in HCC cell lines and tissue samples by real-time reverse transcriptionpolymerase chain reaction, immunoblotting, and/or immunostaining. Expression of various genes in GPC3 siRNA-transfected HCC cells was analyzed. RESULTS:GPC3 was overexpressed in most HCCs at mRNA and protein levels and its serum levels weresignificantly higher in patients with HCC than in non- HCC subjects(P> 0.05).Altered expressions of various MMPs and growth signaling molecules, some of which were correlated with GPC3 expression, were observed in HCCs.Down-regulation of GPC3 expression by siRNA in GPC3-overexpressing HCC cell lines resulted in a significant decrease in expressions of MMP2, MMP14, fibroblast growth factor receptor 1, insulin-like growth factor 1 receptor.GPC3 expression was significantly correlated with nuclear/cytoplasmic localization of 尾-catenin. CONCLUSION:These results suggest that GPC3, in conjunction with MMPs and growth signaling molecules, might play an important role in the progression of HCC.
Role of surgery in colorectal liver metastases:Too early or too late?

As colorectal cancer and colorectal liver metastases become a serious public health problem, new treatment modalities are needed in order to achieve better results. In the last decade there has been very important progress in oncology, with new and more effective chemotherapeutic agents administered alone or in combination improving the resectability rate in up to 40%of patients with colorectal liver metastases. Advances in interventional radiology, in particular, with the use of portal vein embolization and radiofrequency thermal ablation are new strategies allowing major liver resections and treatment of small liver metastases or early recurrences. Surgery, however, remains the gold standard strategy with intention to treat.In this review article we will describe the advanced role of surgery in the multidisciplinary approach to colorectal liver metastases, and the clinical problems the liver surgeon has to deal with, such as theresectability of the metastases, the presence of bilobar liver lesions and extra hepatic disease, the impact of chemotherapy in already resectable liver metastases, the problem of vanishing metastases after chemotherapy and the dilemma of staged or combined liver and colon operations and which organ first in the clinical scenario of synchronous colorectal liver metastases.
Is the disease course predictable in inflammatory bowel diseases?

During the course of the disease, most patients with Crohn's disease(CD) may eventually develop a stricturing or a perforating complication, and a significant number of patients with both CD and ulcerative colitis will undergo surgery.In recent years, research has focused on the determination of factors important in the prediction of disease course in inflammatory bowel diseases to improve stratification of patients, identify individual patient profiles, including clinical, laboratory and molecular markers, which hopefully will allow physicians to choose the most appropriate management in terms of therapy and intensity of follow-up. This review summarizes the available evidence on clinical, endoscopic variables and biomarkers in the prediction of short and long-term outcome in patients with inflammatory bowel diseases.
经阴道彩色多普勒超声对剖宫产切口瘢痕妊娠的诊断价值

剖宫产切口瘢痕妊娠是一种少见特殊类型的异位妊娠,是孕囊着床于子宫下段剖宫产瘢痕处的异位妊娠。随着剖宫产率的升高,发病率有所提高,对子宫瘢痕妊娠(cesarean scarpregnancy, CSP)的报道也逐渐增多。剖宫产切口瘢痕妊娠处理不当,容易发生难以控制的大出血。对该病的早期诊断是决定预后的关键。本文就超声诊断剖宫产切口子宫瘢痕妊娠进行分析,探讨其诊断价值。
Analysis on the stability of the single weld pool formed during the triple-electrode high speed CO_2 welding

The pinch instability theory with free surface and wave superposition principle was applied to understanding the critical disturbance wavelength and the theoretical bead width for the single weld pool formed during the triple-electrode high speed CO_2 welding. In addition, the reason for higher stability in the single weld pool was analyzed. Then single-, twin-, and triple-electrode overlaying experiments were conducted. It was found that triple-electrode CO_2welding can improve welding efficiency greatly without reducing the weld quality. The results indicated that the oscillation frequency of the weld pool increased, oscillation wavelength decreased, and bead width increased with the increase of welding electrodes under the same disturbance circumstances.
Response of Two Jerusalem Artichoke (Helianthus tuberosus) Cultivars Differing in Tolerance to Salt Treatment

To explore genetic variability for two Jerusalem artichoke (Helianthus tuberosus) cultivars, N1 (the sixth-generation cultivated with 75% seawater irrigation for six years) and N7 (a general variety), a experiment was conducted to study the changes in physiological attributes under different concentrations (0%, 10% and 25% of seawater concentration in greenhouse and 0%, 30% and 50% of seawater concentration in the field) of seawater salinity stress. In the greenhouse experiment, decreases of dry growth rate, but increases of dry matter percentage and membrane injury occurred in both the genotypes at 10% and 25% seawater treatments, although lesser cell membrane damage was observed in N1 than N7. N1 accumulated greater contents of Na+, Cl-, soluble sugar and proline in leaves compared with N7. In the field experiment, the yields of shoot, root and tuber, and the contents of total-sugar and inulin in tubers of N1 were higher than those of N7. Lesser degree of salt injury in N1 indicated that the relatively salt-tolerant cultivar had higher K+/Na+ ratio, lower Na~+/Ca~(2+) ratio, and the salt-induced enhancement of osmotic adjustment.
Characterization of Placic Horizons in Ironstone Soils of Louisiana, USA

Placic horizons, defined as thin, wavy, hardened layers of iron and organic matter, are rare within the United States, occurring only in Washington, Alaska, and Hawaii. While ironstone is common in many soils of the southeastern United States, it is not known to contain appreciable organic matter. As a pilot study evaluating the justification for a larger study on ironstone in Louisiana, a 40 m lateral exposure with suspected placic horizons was evaluated in Vernon Parish, Louisiana. Results of laboratory analysis show elevated levels of iron and organic matter in the suspect horizons that meet the criteria of placic horizons as defined by the Soil Survey Staff. Based on the results of this study, additional evaluation of multiple pedons with similar features is warranted. Should additional pedons demonstrate similar properties, a new great group of 'Petrudepts' would be needed to describe both the placic horizons in the pedon and the udic moisture regime in which they occur.
Composition of Wheat Rhizosphere Antagonistic Bacteria and Wheat Sharp Eyespot as Affected by Rice Straw Mulching

To assess the effect of rice straw mulching on changes of antagonistic bacteria and the incidence of wheat sharp eyespot, a multi-year field study was performed to compare unmulched plots and the plots mulched with rice straw for two or three years. Bacterial and fungal populations were evaluated in the cultures prepared from the wheat rhizosphere and bulk soils. Rice straw mulching increased the number of pseudomonas colony forming units in wheat rhizosphere and bulk soils. The proportion of total bacteria that were fluorescent pseudomonads was higher in mulched than in unmulched soil. Bacterial isolates antagonistic to Rhizoctonia cerealis were identified using an inhibition zone test. A series of these isolates were typed by partial sequencing of the 16S rRNA gene. Pseudomonads had higher antagonistic activity against R. cerealis than other species, and more than 80% of rhizosphere fluorescent pseudomonads were antagonistic to R. cerealis. The disease indices were lower in the mulched plots than in the unmulched control. These results suggest that rice straw mulching in a rice-wheat rotation increases the number of fluorescent pseudomonads. Additionally, these fluorescent pseudomonads may contribute to the control of wheat sharp eyespot.
Root Physiological and Morphological Characteristics of Two Rice Cultivars with Different Nitrogen-Use Efficiency

The variation in nitrogen (N) uptake by rice has been widely studied but differences in rice root morphology that may contribute to this variation are not completely understood. Field and greenhouse experiments were carried out to study N accumulation, root dry weights, total root lengths, root surface areas, and root bleeding rates of two rice cultivars, Elio with low N-use efficiency and Nanguang with high N-use efficiency. Low (1 mmol N L~(-1)) and high (5 mmol N L~(-1)) N applications were established in the greenhouse experiment, and the N rates were 0, 120, and 240 kg ha~(-1) in the field experiments at Jiangning and Jiangpu farms, Nanjing, China. The results showed that the N accumulation, root dry weight, total root length, and root surface area increased with an increase in N application. At the heading stage, N accumulation in the shoots and roots of Nanguang was greater than that of Elio in the field experiments and that of Elio at 5 mmol N L~(-1) in the greenhouse experiment. After the heading stage, N accumulation was higher for Nanguang at both 1 and 5 mmol N L~(-1) in the greenhouse experiment. The total root length and root surface area were significantly different between the two cultivars. Over the range of the fertilizer application rates, the root lengths of Nanguang at Jiangning Farm were 49%-61% greater at booting and 26%-39% greater at heading than those of Elio, and at Jiangpu Farm they were 22%-42% and 26%-38% greater, respectively. Nanguang had a greater root bleeding rate than Elio. It was concluded that the N-use efficiency of the two rice cultivars studied depended to a great extent on the root morphological parameters and root physiological characteristics at different growth stages.
超声诊断静脉平滑肌瘤病1例

子宫肌瘤是一种最常见的女性生殖器官肿瘤，但子宫静脉内平滑肌瘤(IVL)是一种罕见的、特殊类型的子宫肌瘤，虽然在病理学上属良性肿瘤，但其生长方式类似恶性肿瘤. 肌瘤可以在盆腔的血管内生长，随后沿着分支进入髂静脉及下肢静脉，并不断向上生长，最后进入右心房和右心室，这个过程可能需要几年甚至十几年，常无明显症状. 当瘤体堵塞下肢静脉或三尖瓣151时，静脉血流回流受阻，患者会出现下肢水肿、腹壁静脉曲张、心悸、气促等表现. 当瘤体堵塞肺动脉瓣口时，患者还可出现体位性低血压、晕厥和猝死等情况. IVL是激素依赖型肿瘤，若有组织残留极易复发，所以手术原则上行全子宫及双附件切除术，并将子宫外的肿瘤组织彻底清除干净. 因此，正确的术前诊断是做好充分术前准备的基础. 本病应注意与黏液瘤、心脏恶性肿瘤、心房内血栓等相鉴别. 黏液瘤、心脏恶性肿瘤主要发生于心腔内，偶有生长于肺动脉内，生长于下腔静脉罕见；右房血栓亦可来自下腔静脉，超声鉴别困难，须进一步病理诊断. 但本例患者有子宫肌瘤病史，且回声光团自下腔静脉一直延续到右房，故考虑为静脉内平滑肌瘤病.
脑膜瘤致颅内血肿1例

讨论脑膜瘤是颅内常见的肿瘤，脑膜瘤来源于被覆蛛网膜的间质细胞及软硬脑膜的纤维细胞，多为良性，呈膨胀性生长，可有局部浸润，突入脑组织中生长缓慢，占所有颅内肿瘤的 13％～26％. 颅内肿瘤卒中较少见，而脑膜瘤以卒中出血引起首发症状者更是罕见，Wakai等报道脑肿瘤1861例中310例为脑膜瘤，只有3例有脑出血(1．3％)；有学者报道125例脑膜瘤中，有3例为出血起病(2．4％). 脑膜瘤卒中出血可为脑内血肿、硬脑膜下血肿、肿瘤内出血、脑室内出血，或上述出血类型合并存在，以大脑凸面脑膜瘤最多见，其次为矢状窦旁、蝶骨脊、颞叶、嗅沟、桥脑小脑脚、侧脑室、斜坡和枕骨大孔脑膜瘤. 而本例患者出血位于左颞叶脑膜瘤周围形成血肿非常罕见.