mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Synchronization Transition of Time Delayed Complex Dynamical Networks with Discontinuous Coupling

This paper investigates the synchronization of time delayed complex dynamical networks with periodical on-off coupling. Both the theoretical and numerical results show that, in spite of time delays and on-off coupling, two networks may synchronize if the coupling strength and the on-off rate are large enough. It is shown that, for undirected and strongly connected networks, the upper bound of time delays for synchronization is a decreasing function of the absolute value of the minimum eigenvalue of the adjacency matrix. The theoretical analysis confirms the numerical results and provides a better understanding of the influence of time delays and on-off coupling on the synchronization transition. The influence of random delays on the synchronization is also discussed.
Characterization by microarray and meiotic segregation study of a der(10)t(10;18) in a patient with infertility and normal phenotype

Carriers of balanced chromosomal rearrangements, including reciprocal, robertsonian translocations, and inversions, have all genetic information conserved. Nevertheless, because of the possibility of defect in chromosome segregation during gametogenesis, carriers of balanced rearrangements have an increased risk of spontaneous abortion and/ or a chromosomally unbalanced child with intellectual deficiency or multiple congenital malformations. Unbalanced translocations in patients with normal phenotype are rarely described. Only three unbalanced translocations involving acrocentric chromosome with meiotic defects were reported in the literature in infertile men.
铝/黄铜异种金属TIG填丝熔钎焊工艺

采用TIG熔钎焊进行5052铝合金和H62黄铜搭接,选用Al-12%Si药芯焊丝作为填充材料,并对接头微观组织和力学性能进行分析.结果表明,Al-12%Si药芯焊丝在黄铜母材表面润湿性较差,较难获得优质的熔钎焊接头.焊缝中黄铜侧界面层附近过渡区内铝含量较高,与部分熔化和溶解的黄铜母材形成了尺寸较大的条状AlCu金属间化合物相,严重影响接头力学性能.黄铜母材侧界面层由两层不同的金属间化合物相组成,从焊缝到黄铜母材分别为CU_9Al_4和CuZn.拉伸试验中,试样断裂于黄铜侧过渡区或界面层,断口呈现解理断裂的特征.
基于BP神经网络的钢轨闪光对焊接头灰斑面积预测

针对钢轨闪光对焊的特点,根据GAAS80/580焊机记录的压力、电流和动端位移随时间而变化的曲线,从中提取了10个主要影响接头灰斑面积的特征参数作为BP神经网络预测模型的输人量,建立了钢轨闪光对焊接头的灰斑面积预测模型.采用粒子群算法优化了BP神经网络的权值和阈值,并利用优化后的BP网络模型对接头灰斑面积进行了预测.结果表明,提取的特征参数能较好地反映焊接接头灰斑情况,粒子群算法优化的BP神经网络预测模型能较准确地预测出焊接接头灰斑面积.
采用Au基钎料真空钎焊Al_2O_3陶瓷

首先选用AgCuTi活性钎料在880 ℃/10 min参数下对Al_2O_3陶瓷表面进行金属化处理,之后尽量去除金属化层中的AgCu共晶组织,然后选用两种Au基高温钎料在980℃/10 min参数下对金属化后的Al_2O_3进行了钎焊连接.结果表明,在Al_2O_3/Au-Ni/Al_2O_3接头中靠近Al_2O_3母材的界面处生成一层薄薄的扩散反应层,该反应层主要由TiO_2和Al_2O_3组成;在Al_2O_3/Au-Cu/Al_2O_3接头中同样存在扩散反应层,与前者不同的是,接头中检测到Ti-Au相的存在.分别对Au-Ni和Au-Cu两种钎料获得的Al_2O_3接头进行了抗剪强度测试,前者对应接头强度为95.5 MPa,后者对应接头强度达到102.3 MPa.
Study on the influence of meteorological conditions and the street side buildings on the pollutant dispersion in the street canyon

As cities grow, automobile exhaust pollution is worsening, which has become a major problem of air pollution, even it is a serious threat to the physical and mental health of residents. Thus, to study its diffusion law and influential factors occupies a count for much position. The paper analyzes the factors that affect the dispersion of urban vehicle emissions in street canyon to evaluate the research method of pollutant dispersion. In addition, the influences of different wind speeds and wind directions, the roof shape of buildings on both street sides, and the relative height of the two sides of buildings on the street canyon, on airflow field and pollutant dispersion are simulated. It is shown that the wind speed, the wind direction and the buildings on both sides have a great impact on the airflow and contaminant dispersion in the street canyon. The results provide scientific basis for controlling, monitoring and evaluating the urban motor vehicle emissions, besides the reasonable layout and the programme of urban streets.
Dual-Source Nuclear Monomers of UV-B Light Receptor Direct Photomorphogenesis in Arabidopsis

The ultraviolet (UV)-B wavelength (280-315 nm) is an indispensable component of the sunlight that reaches the earth's surface. Long-wavelength and low-fluence UV-B specifically induces plant photomorphogenesis, which is characterized by inhibition of hypocotyl elongation, promotion of anthocyanin accumulation, and eventually tolerance against UV-B stress (Jenkins, 2009). In Arabidopsis thaliana, UV-B light is perceived by UV RESISTANCE LOCUS 8 (UVR8), a plant-specific chromoprotein. UVR8 forms a symmetric homodimer in the absence of UV-B light. The tryptophan residues on the surface of the UVR8 dimer serve as the intrinsic chromophore to sense UV-B light. Upon UV-B irradiation, the homodimeric interface, which is stabilized by arginine residues, is disrupted, leading to monomerization of UVR8 (Rizzini et al., 2011; Christie et al., 2012; Wu et al., 2012). UVR8 is present in both the cytoplasm and the nucleus, and UV-B treatment stimulates the accumulation of UVR8 in the nucleus (Kaiserli and Jenkins, 2007). However, it is not clear how UV-B regulates the subcellular localization and physiological activity of UVR8. In this study, we explore the mechanism of the buildup of the nuclear UVR8 pool, dissect physiological roles of subcellular UVR8, and reveal positive and negative regulators of UVR8 localization in the photomorphogenic UV-B signaling process.
Unimpaired immunogenicity of yeast-expressed hepatitis B surface antigen stored at elevated temperatures

Global adoption of hepatitis B virus (HBV) vaccines has greatly reduced new HBV infections. Current HBV vaccines are liquid suspensions containing recombinant hepatitis B surface antigen (HBsAg) particles mixed with aluminum phosphate or aluminum hydroxide. Refrigeration (2-8°C) as recommended for vaccine transport and storage may be unachievable in certain HBV-prevalent developing countries or regions. In this study, we stored yeast-expressed HBsAg and aluminum hydroxide separately at the standard (4°C) and elevated temperature (25, 37, or 45°C) for 14, 23, and 30 days,then mixed them and used the mixture to vaccinate mice with a prime-boost program. The antisera from all the vaccinated mice successfully inhibited HBV infection of HepG2 cells stably expressing HBV receptor sodium taurocholate cotransporting polypeptide. Furthermore, no serum HBsAg was detected in vaccinated mice on Day 1 post-hydrodynamic injection (HDI) of an HBV replicon plasmid and onwards, accompanied with an increasing anti-HBsAg antibody (HBsAb) level. In contrast, serum HBsAg in phosphate-buffered saline (PBS)-injected mice peaked on Day 4 post-HDI and was cleared on Day 14 post-HDI, which coincided with appearance of HBsAb on Day 7 post-HDI, suggesting a typical HBV acute infection process. HBV DNA peaked on Day 4 post-HDI in vaccinated mice, its level significantly lower than that in PBS-injected mice on Day 7 post-HDI, and showed a higher clearance rate. Taken together, we conclude that storing recombinant HBsAg at 25, 37, or 45°C for 14-30 days does not impair its immunogenicity in mice.
Distinct effects of mutations on biophysical properties of human prion protein monomers and oligomers

Prion diseases are a group of fatal neurodegenerative illnesses, resulting from the conformational conversion of the cellular prion protein (PrP~c) into a misfolded form (PrP~(Sc)). The formation of neurotoxic soluble prion protein oligomer (PrP~O) is regarded as a key step in the development of prion diseases. About 10%-15% of human prion diseases are caused by mutations in the prion protein gene; however, the underlying molecular mechanisms remain unclear. In the present work, we compared the biophysical properties of wild-type (WT) human prion protein 91-231(WT HuPrP_(91-231)) and its disease-associated variants (P105L, D178N, V203I, and Q212P) using several biophysical techniques. In comparison with WT HuPrP~c, the Q212P and D178N variants possessed greatly increased conversion propensities of PrP~c into PrP~O, while the V203I variant had dramatically decreased conversion propensity. The P105L variant displayed a similar conversion propensity to WT HuPrP~c. Guanidine hydrochloride-induced unfolding experiments ranked the thermodynamic stabilities of these proteins as Q212P < D178N < WT≈ P105L< V203I. It was thus suggested that the conversion propensities of the prion proteins are closely associated with their thermodynamic stabilities. Furthermore, structural comparison illustrated that Q212P, D178N, and V203I variants underwent larger structural changes compared with WT HuPrPc, while the P105L variant adopted a similar structure to the WT HuPrP~C. The mutation-induced structural perturbations might change the thermodynamic stabilities of the HuPrP~c variants, and correspondingly alter the conversion propensities for these prion proteins. Our results extend the mechanistic understanding of prion pathogenesis, and lay the basis for the prevention and treatment of prion diseases.
Ricin-B-lectin enhances microsporidia Nosema bombycis infection in BmN cells from silkworm Bombyx mori

Nosema bombycis is an obligate intracellular parasitic fungus that utilizes a distinctive mechanism to infect Bombyx mori. Spore germination can be used for host cell invasion; however, the detailed mechanism remains to be elucidated. The ricin-B-lectin (RBL) gene is significantly differentially regulated after N. bombycis spore germination, and NbRBL might play roles in spore germination and infection. In this study, the biological function of NbRBL was examined. Protein sequence analysis showed that NbRBL is a secreted protein that attaches to carbohydrates. The relative expression level of the NbRBL gene was low during the first 30 h post-infection (hpi) in BmN cells, and high expression was detected from 42 hpi. Gene cloning, prokaryotic expression, and antibody preparation for NbRBL were performed. NbRBL was detected in total and secreted proteins using western blot analysis. Subcellular localization analysis showed that NbRBL is an intracellular protein. Spore adherence and infection assays showed that NbRBL could enhance spore adhesion to BmN cells; the proliferative activities of BmN cells incubated with anti-NbRBL were higher than those in negative control groups after N. bombycis infection; and the treatment groups showed less damage from spore invasion. We therefore, propose that NbRBL is released during spore germination, enhances spore adhesion to BmN cells, and contributes to spore invasion.
Short-term serum deprivation causes no significant mitochondrial DNA mutation in vascular smooth muscle cells revealed by a new next generation sequencing technology

Mitochondrion provides much of the energy for the cell and the disorder in mitochondrion can affect almost any tissue. The mitochondrial DNA (mtDNA) covers 16,569 bp, consisting of 37 genes and 1 D-Loop region in human. Mitochondrion is unique in possessing their own genome which is organized into mitochondrial nucleoids by employing multiprotein machineries, and can perform the functions of gene replication, transcription, and repair. Although it has almost all known nuclear DNA repair pathways, the lack of protective histones may lead to particular susceptibility to stresses and DNA damage events. Indeed, the mtDNA has a very high mutation rate. Since its discovery, mtDNA mutation has been known to be common and has emerged as an important cause of human diseases including diabetes, cardiovascular diseases, cancers, neuromuscular disorders, and aging, affecting 1 in 4300 of the population. Thus, identifying mtDNA mutations in stresses and diseases is now a hot research area.
Open-Type Ferry Safety System Design for Using LNG Fuel

In this feasibility study, we investigate the viability of using Liquefied Natural Gas (LNG) fuel in an open type Ro-Ro passenger ferry and the associated potential challenges with regard to the vessel safety systems. We recommend an appropriate methodology for converting existing ships to run on LNG fuel, discuss all the necessary modifications to the ship’s safety systems, and also evaluate the relevant ship evacuation procedures. We outline the basic requirements with which the ship already complies for each safety system and analyze the additional restrictions that must be taken into consideration for the use of LNG fuel. Appropriate actions are recommended. Furthermore, we carry out a hazard identification study. Overall, we clearly demonstrate the technical feasibility of the investigated scenario. Minimal modifications to the ship’s safety systems are required to comply with existing safety rules for this specific type of ship.
Development of high-strength, low-cost wrought Mg–2.0 mass% Zn alloy with high Mn content

Mg–Zn–Mn-based alloys have received considerable attention because of their high creep resistance, strength, and good corrosion resistance. The alloying element Mn in Mg–Zn-based alloys is commonly less than 1 wt%. In the present study, the effect of high Mn content (1 wt% and 2 wt%) on the microstructures and mechanical properties of Mg–2Zn–0.3Sr extruded alloy was investigated. The results revealed that the high Mn content significantly increased the ultimate tensile strength, tensile yield strength, compress yield strength, and yield asymmetry of the alloy without affecting its ductility. The dynamically recrystallized (DRXed) grains of Mg– 2Zn–0.3Sr were remarkably refined because of the large amount of fine Mn precipitates in the homogenized alloy. The improved strengths were mainly attributed to the fine DRXed grains according to the Hall–Petch effect and to the large amount of spherical and < 0001 > Mn precipitates through the precipitation and dispersion strengthening. The fine DRXed grains and numerous Mn precipitates effectively suppressed the extension twining, substantially enhanced the compress yield strength, and resulted in improved anisotropy.
Micromechanical Modeling of Elastic-Viscoplastic Behavior of Armco-Fe at High Strain Rate

Heterogeneous dynamical stress-strain response of Armco-Fe was investigated at high strain rates through the Split Hopkinson Pressure Bar (SHPB) testing. It was found that the viscoplastic deformation in BCC ferrite grains is affected by the strain rate. Thermal softening and variation in crystal orientations under high-strain-rate loading were used in the elastic-viscoplastic modeling. The micromechanical analysis with self-consistent transition and homogenization was used for estimation of the global impact response of the material. The results from modeling were found in good agreement with the experimental data.
An Internal Expansive Stress Model of Concrete under Sulfate Attack

Concrete experiences expansive deformation during sulfate attack due to internal expansive stress. Sulfate ions enter concrete pores, react with the pore solution, and produce ettringite. The production of ettringite explains the internal expansive stress that reduces the durability of concrete. In this study, the model of internal expansive stress was achieved through the Eshelby's theory, as well as the experimental results for concrete erosion. Numerical simulation indicated that internal expansive stress is not only determined by the water-to-cement ratio of concrete and the concentration of sulfate solution, but also affected by the relaxation time of concrete.
Evaluation of Weather Research and Forecasting Model Parameterizations under Sea-Breeze Conditions in a North Sea Coastal Environment

Three atmospheric boundary layer(ABL) schemes and two land surface models that are used in the Weather Research and Forecasting(WRF) model, version 3.4.1, were evaluated with numerical simulations by using data from the north coast of France(Dunkerque). The ABL schemes YSU(Yonsei University), ACM2(Asymmetric Convective Model version 2), and MYJ(Mellor-Yamada-Janjic) were combined with two land surface models, Noah and RUC(Rapid Update Cycle), in order to determine the performances under sea-breeze conditions. Particular attention is given in the determination of the thermal internal boundary layer(TIBL), which is very important in air pollution scenarios. The other physics parameterizations used in the model were consistent for all simulations. The predictions of the sea-breeze dynamics output from the WRF model were compared with observations taken from sonic detection and ranging, light detection and ranging systems and a meteorological surface station to verify that the model had reasonable accuracy in predicting the behavior of local circulations. The temporal comparisons of the vertical and horizontal wind speeds and wind directions predicted by the WRF model showed that all runs detected the passage of the sea-breeze front. However, except for the combination of MYJ and Noah, all runs had a time delay compared with the frontal passage measured by the instruments. The proposed study shows that the synoptic wind attenuated the intensity and penetration of the sea breeze. This provided changes in the vertical mixing in a short period of time and on soil temperature that could not be detected by the WRF model simulations with the computational grid used. Additionally, among the tested schemes, the combination of the localclosure MYJ scheme with the land surface Noah scheme was able to produce the most accurate ABL height compared with observations, and it was also able to capture the TIBL.
The Role of Nonlinear Forcing Singular Vector Tendency Error in Causing the \Spring Predictability Barrier" for ENSO

With the Zebiak-Cane model, the present study investigates the role of model errors represented by the nonlinear forcing singular vector(NFSV) in the \spring predictability barrier"(SPB) phenomenon in ENSO prediction. The NFSV-related model errors are found to have the largest negative effect on the uncertainties of El Ni~no prediction and they can be classified into two types: the first is featured with a zonal dipolar pattern of SST anomalies(SSTA), with the western poles centered in the equatorial central-western Pacific exhibiting positive anomalies and the eastern poles in the equatorial eastern Pacific exhibiting negative anomalies; and the second is characterized by a pattern almost opposite to the first type. The first type of error tends to have the worst effects on El Ni~no growth-phase predictions, whereas the latter often yields the largest negative effects on decaying-phase predictions. The evolution of prediction errors caused by NFSV-related errors exhibits prominent seasonality, with the fastest error growth in spring and/or summer; hence, these errors result in a significant SPB related to El Ni~no events. The linear counterpart of NFSVs, the(linear) forcing singular vector(FSV), induces a less significant SPB because it contains smaller prediction errors. Random errors cannot generate an SPB for El Ni~no events. These results show that the occurrence of an SPB is related to the spatial patterns of tendency errors. The NFSV tendency errors cause the most significant SPB for El Ni~no events. In addition, NFSVs often concentrate these large value errors in a few areas within the equatorial eastern and central-western Pacific, which likely represent those areas sensitive to El Ni~no predictions associated with model errors. Meanwhile, these areas are also exactly consistent with the sensitive areas related to initial errors determined by previous studies. This implies that additional observations in the sensitive areas would not only improve the accuracy of the initial field but also promote the reduction of model errors to greatly improve ENSO forecasts.
Projection of Summer Precipitation over the Yangtze-Huaihe River Basin Using Multimodel Statistical Downscaling Based on Canonical Correlation Analysis

By using observational daily precipitation data over the Yangtze-Huaihe River basin, ERA-40 data, and the data from eight CMIP5 climate models, statistical downscaling models are constructed based on BP-CCA(combination of empirical orthogonal function and canonical correlation analysis) to project future changes of precipitation. The results show that the absolute values of domain-averaged precipitation relative errors of most models are reduced from 8%-46% to 1%-7% after statistical downscaling. The spatial correlations are all improved from less than 0.40 to more than 0.60. As a result of the statistical downscaling multimodel ensemble(SDMME), the relative error is improved from -15.8% to -1.3%, and the spatial correlation increases significantly from 0.46 to 0.88. These results demonstrate that the simulation skill of SDMME is relatively better than that of the multimodel ensemble(MME) and the downscaling of most individual models. The projections of SDMME reveal that under the RCP(Representative Concentration Pathway) 4.5 scenario, the projected domain-averaged precipitation changes for the early(2016-2035), middle(2046-2065), and late(2081-2100) 21 st century are -1.8%, 6.1%, and 9.9%, respectively. For the early period, the increasing trends of precipitation in the western region are relatively weak, while the precipitation in the east shows a decreasing trend. Furthermore, the reliability of the projected changes over the area east of 115flE is higher than that in the west. The stations with significant increasing trends are primarily located over the western region in both the middle and late periods, with larger magnitude for the latter. Stations with high reliability mainly appear in the region north of 28.5flN for both periods.
Possible Combined Influences of Absorbing Aerosols and Anomalous Atmospheric Circulation on Summertime Diurnal Temperature Range Variation over the Middle and Lower Reaches of the Yangtze River

Based on the temperature data from the China Meteorological Administration, NCEP-NCAR reanalysis data, and the TOMS Aerosol Index(AI), we analyze the variations in the summertime diurnal temperature range(DTR) and temperature maxima in the middle and lower reaches of the Yangtze River(MLRYR) in China. The possible relationships between the direct warming effect of the absorbing aerosol and temperature variations are further investigated, although with some uncertainties. It is found that the summertime DTR exhibits a decreasing trend over the most recent 50 years, along with a slight increasing tendency since the 1980 s. The trend of the maximum temperature is in agreement with those of the DTR and the absorbing aerosols. To investigate the causes of the large anomalies in the temperature maxima, composite analyses of the circulation anomalies are performed. When anomalous AI and anomalous maximum temperature over the MLRYR have the same sign, an anomalous circulation with a quasi-barotropic structure occurs there. This anomalous circulation is modulated by the Rossby wave energy propagations from the regions northwest of the MLRYR and influences the northwestern Pacific subtropical high over the MLRYR. In combination with aerosols, the anomalous circulation may increase the maximum temperature in this region. Conversely, when the anomalous AI and anomalous maximum temperature in the MLRYR have opposite signs, the anomalous circulation is not equivalently barotropic, which possibly offsets the warming effect of aerosols on the maximum temperature changes in this region. These results are helpful for a better understanding of the DTR changes and the occurrences of temperature extremes in the MLRYR region during boreal summer.
践行绿色发展理念--推进茶园化肥农药减施

我国是世界上最大的产茶国,茶叶也是我国主要的出口农产品之一,在当前农民增收、农业增长、农村稳定中具有重要现实意义。化肥农药过量施用不仅增加生产成本和危及生态环境安全,因此导致的茶叶质量安全问题受社会高度关注,也是我国茶叶出口中遇到的一个瓶颈问题。由中国农业科学院茶叶研究所牵头,联合多个国家级科研院所、高等院校以及省级农技推广部门申报的“茶园化肥农药减施增效技术集成研究与示范”正式获批立项,计划在5年内通过共性技术突破与集成创新,技术模式的推广应用,实现我国茶园化肥农药的减施增效目标。该项目的顺利实施,将为茶叶生产的绿色安全、节约高效提供有力的技术支撑,对我国茶产业的可持续发展,以及农村生态文明建设具有重要意义。
主要农作物产量性状形成的分子基础研究与展望

保障国家粮食安全是关系我国国民经济发展和社会稳定的重大战略问题。常规育种面临育种周期长、效率低、遗传背景狭窄等瓶颈,难以培育出产量突破性新品种。因此,育种理论与技术创新是现代种业发展的迫切需求。由中国科学院遗传发育生物学研究所傅向东研究员牵头申报的国家重点研发计划“主要农作物产量性状形成的分子基础”项目获得科技部立项支持,通过利用水稻、小麦、玉米、大豆等主要农作物的野生种、农家种、主栽品种和优异种质材料,试图解析产量性状形成的分子基础,从“增源–扩库–畅流”三个层面上发掘优异等位基因,在当前主栽品种中聚合优异等位基因,创制产量突破性新材料。为分子设计育种技术体系创新提供理论和技术支撑。
主要农作物抗病虫抗逆性状形成的分子基础

作物抗病抗虫和抗逆性状是农作物育种的关键目标,也是高度复杂的农艺性状和学科研究前沿。国家重点研发计划“主要农作物抗病虫抗逆性状形成的分子基础”项目围绕我国农作物重要育种目标,聚集核心研究队伍,设置5个相关研究课题,以建立农作物抗病虫抗逆高水平研究体系为目标,重点鉴定对主要病虫害(水稻稻瘟病、纹枯病、黑条矮缩病、小麦锈病、白粉病、赤霉病、玉米茎腐病、大豆胞囊线虫、油菜菌核病、水稻稻飞虱、螟虫、大豆蚜虫等)、主要逆境因子(干旱/水分利用、盐碱、高温、低温)的抗性控制的主基因和主效QTL,解析性状形成的分子遗传机制及调控网络;系统发掘有重要育种价值的抗性优异等位基因,并提出育种应用途径。该项目的开展将建立我国主要农作物抗性育种的理论与技术体系,保障我国农作物高产稳产的育种目标,占据作物多抗分子育种的国际领先地位。