mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
A new technology for hard-rock tunneling based on drilling and hydraulic impact breaking

In order to realize the safety, high efficiency and rapidity of hard rock tunneling, we propose the drilling & hydraulic impact hard-rock tunneling (DHIHT) technology and method. Based on the LS-DYNA explicit module and APDL programming, the key parameters of DHIHT, including drilling spacing and drilling radius, were investigated. The simulation results show that: the drilling spacing should not exceed 0.20 m-larger distances weaken the actual breaking effect; the best drilling radius is about 0.035 m, larger or smaller distances would both decrease the effect of drilling-hole free surfaces. The field impact breaking experiments were conducted in Baitaizi township granite quarry, Jinzhou, Liaoning province, China. The experiment results indicate that DHIHT is a feasible method for hard-rock tunneling, but its efficiency still needs to be further optimized and improved.
Modeling and prediction of daily gas concentration variation at a mining face based on the elliptic orbit model: A case study

Monitoring and analysis of daily gas concentrations at a mining face is a vital task on safety production and security management in the coal-mining industry. This study addresses modeling and prediction of daily gas concentration variations based on the elliptic orbit model. The model describes the hourly variation in daily gas concentration by mapping its time-series into the polar coordinates to create its elliptic orbit trace for further analysis. Experiments show workability of the proposed method that daily gas concentration variation at a mining face of one coal mine in China is well described by the elliptic orbit model. Result analysis and performance comparison of the proposed elliptic orbit model with the classical AR model on the same prediction tasks indicate potentiality of the proposed elliptic orbit model, which presents a vivid approach for modeling and forecasting daily gas concentration variations in an intuitive and concise way.
Auxiliary transportation mode in a fully-mechanized face in a nearly horizontal thin coal seam

On fully-mechanized faces in nearly horizontal thin coal seams (NHTCS), the selection of the auxiliary transportation mode is difficult. Generally, auxiliary transportation mainly includes trackless or rail transportation. Combined with a familiar NHTCS fully-mechanized face, a multi-attribute decisionmaking model was set up for the decision. The index weight was objectively determined with the fuzzy number and entropy method. The priority order of auxiliary transportation modes was obtained from the Preference Ranking Organization Method for Enrichment Evaluation (PROMETHEE). The results show that: the net flow of the mode can be expressed by the function of the surrounding rock deformation of the roadway, the dimension of equipment and the thickness of the coal seam; Based on the cost type index, there is a positive correlation between the net flow with the height and width of the trackless auxiliary transportation equipment, respectively. The trackless auxiliary transportation equipment selection principle should be "height first then width". Combined with the field application of the trackless auxiliary transportation in Liangshuijing coal mine, the proper method to achieve the safe and high-efficient exploitation of a NHTCS fully-mechanized face is trackless tyred vehicle auxiliary transportation.
Effect of auxiliary ventilations on diesel particulate matter dispersion inside a dead-end entry

Diesel particulate matter (DPM) is considered carcinogenic after prolonged exposure. This paper used computational fluid dynamics (CFD) method to study the effect of four auxiliary ventilation systems on DPM distribution in a dead-end entry with loading operation. The auxiliary ventilation systems considered include: blower fan and tubing; exhaust fan and tubing, jet fan, and push-pull system. A species transport model with buoyancy effect was used to examine the DPM dispersion pattern with unsteady state analysis. During the 200 s of the loading operation, high DPM levels were identified in the face and dead-end entry regions. This study can be used for mining engineer as guidance to design and setup of local ventilation. It can also be used for selection of DPM control strategies and DPM annual training for underground miners.
Underground mining of thick coal seams

This paper reviews underground mining methods for total thickness of a thick coal seam in single lift (TTTCSSL). Review shows the required engineering for extraction of thick seams needs to be fitted with thickness of the seam, behavior of rock-mass and surrounding stress conditions for efficient mining. Variants of TTTCSSL are able to extract a maximum 10-12 m thickness only. An improvement in bending moment of the overlying coal band in longwall top coal caving (LTCC) provides better under-winning opportunity for the roof coal band. An acceptable limit of 25 MPa compressive strength of coal for the success of LTCC may be increased under favorable geo-technical conditions. Bord and pillar in India adopted induced caving of roof coal band for single lift depillaring of total thickness (SLDTT) of a competent thick coal seam developed along floor. Case studies are given to arrest the adverse effects of extraction height on pillars.
Longwall automation: Delivering enabling technology to achieve safer and more productive underground mining

The ongoing need to deliver improved safety, productivity and environmental benefit in coal mining presents an open challenge as well as a powerful incentive to develop new and improved solutions. This paper assesses the critical role that enabling technologies have played in the delivery of remote and automated capability for longwall mining. A brief historical account is given to highlight key technical contributions which have influenced the direction and development of present-day longwall technology. The current state of longwall automation is discussed with particular attention drawn to the technologies that enable automated capability. Outcomes are presented from an independently conducted case study that assessed the impact that CSIRO’s LASC longwall automation research has made to the longwall mining industry in Australia. Importantly, this study reveals how uptake of this innovative technology has significantly benefitted coal mine productivity, improved working conditions for personnel and enhanced environmental outcomes. These benefits have been widely adopted with CSIRO automation technology being used in 60 per cent of all Australian underground operations. International deployment of the technology is also emerging. The paper concludes with future challenges and opportunities to highlight the ongoing scope for longwall automation research and development.
Entropy change-induced elastic softening of lithiated materials

To understand the "elastic softening" of Li-Si alloys for the development of Li-ion batteries, the effect of stress-induced change of entropy on the mechanical properties of lithiated materials is examined within the theories of thermodynamics and linear elasticity. An approach is presented whereby the change of Gibbs free energy is governed by the change of the mixture entropy due to stress-induced migration of mobile atoms, from which the contribution of the change of the mixture entropy to the apparent elastic modulus of lithiated materials is determined. The reciprocal of the apparent elastic modulus of a lithiated material is a linear function of the concentration of mobile Li-atoms at a stress-free state and the square of the mismatch strain per unit mole fraction of mobile Li-atoms.
Effect of viscoelasticity on skin pain sensation

Pain sensation may appear under long-lasting mechanical stimulation. Although people have the experience that pain sensation generally decreases with time while the stimulation remains, the underlying mechanism remains elusive. We experimentally studied the thermal and strain ratedependent viscoelastic behavior of skin in uniaxial stretch and numerically investigated the effects of temperature and strain rate on pain sensation. The results indicate that the viscosity of skin tissue decreases with increasing temperature and reducing strain rate, which subsequently decreases the discharge frequency of skin nociceptor and thus relieves the pain sensation. The results would contribute to the understanding of pain relief mechanism and optimizing for mechanical treatment.
Revisiting the Bjerrum's correction factor: Use of the liquidity index for assessing the effect of soil plasticity on undrained shear strength

The undrained shear strength (su) of fine-grained soils that can be measured in situ and in laboratory is one of the key geotechnical parameters. The unconfined compression test (UCT) is widely used in laboratory to measure this parameter due to its simplicity; however, it is severely affected by sample disturbance. The vane shear test (VST) technique that is less sensitive to sample disturbance involves a correction factor against the soil plasticity, commonly known as the Bjerrum's correction factor, μ. This study aims to reevaluate the Bjerrum's correction factor in consideration of a different approach and a relatively new method of testing. Atterberg limits test, miniature VST, and reverse extrusion test (RET) were conducted on 120 remolded samples. The effect of soil plasticity on undrained shear strength was examined using the liquidity index instead of Bjerrum's correction factor. In comparison with the result obatined using the Bjerrum's correction factor, the undrained shear strength was better represented when su values were correlated with the liquidity index. The results were validated by the RET, which was proven to take into account soil plasticity with a reliable degree of accuracy. This study also shows that the RET has strong promise as a new tool for testing undrained shear strength of fine-grained soils.
Competitive Expression of Endogenous Wheat CENH3 May Lead to Suppression of Alien ZmCENH3 in Transgenic Wheat × Maize Hybrids

Uniparental chromosome elimination in wheat × maize hybrid embryos is widely used in double haploid production of wheat. Several explanations have been proposed for this phenomenon, one of which is that the lack of cross-species CENH3 incorporation may act as a barrier to interspecies hybridization. However, it is unknown if this mechanism applies universally. To study the role of CENH3 in maize chromosome elimination of wheat × maize hybrid embryos, maize ZmCENH3 and wheat αTaCENH3-B driven by the constitutive CaMV35S promoter were transformed into wheat variety Yangmai 158.Five transgenic lines for ZmCENH3 and six transgenic lines for aTaCENH3-B were identified. RT-PCR analysis showed that the transgene could be transcribed at a low level in all ZmCENH3 transgenic lines, whereas transcription of endogenous wheat CENH3 was significantly up-regulated. Interestingly, the expression levels of both wheat CENH3 and ZmCENH3 in the ZmCENH3 transgenic wheat × maize hybrid embryos were higher than those in the non-transformed Yangmai 158 × maize hybrid embryos. This indicates that the alien ZmCENH3 in wheat may induce competitive expression of endogenous wheat CENH3, leading to suppression of ZmCENH3 over-expression. Eliminations of maize chromosomes in hybrid embryos of ZmCENH3 transgenic wheat × maize and Yangmai 158 × maize were compared by observations on micronuclei presence, by marker analysis using maize SSRs (simple sequence repeats), and by FISH (fluorescence in situ hybridization) using 45S rDNA as a probe. The results indicate that maize chromosome elimination events in the two crosses are not significantly different. Fusion protein ZmCENH3-YFP could not be detected in ZmCENH3 transgenic wheat by either Western blotting or immnunostaining, whereas accumulation and loading of the αTaCENH3-B-GFP fusion protein was normal in αTaCENH3-B transgenic lines. As ZmCENH3-YFP did not accumulate after AM114 treatment, we speculate that low levels of ZmCENH3 protein in transgenic wheat may be one of the factors that lead to failure of suppression of maize chromatin elimination in ZmCENH3 transgenic wheat × maize hybrids.
ACAT1 regulates the dynamics of free cholesterols in plasma membrane which leads to the APP-α-processing alteration

Acyl-CoA:cholesterol acyltransferase 1 (ACAT1) is a key enzyme exclusively using free cholesterols as the substrates in cell and is involved in the cellular cholesterol homeostasis. In this study, we used human neuroblastoma cell line SK-N-SH as a model and first observed that inhibiting ACAT1 can decrease the amyloid precursor protein (APP)-α-processing. Meanwhile, the transfection experiments using the small interfering RNA and expression plasmid of ACAT1 indicated that ACAT1 can dependently affect the APP-α-processing. Furthermore, inhibiting ACAT1 was found to increase the free cholesterols in plasma membrane (PM-FC), and the increased PM-FC caused by inhibiting ACAT1 can lead to the decrease of the APP-α-processing, indicating that ACAT1 regulates the dynamics of PM-FC, which leads to the alteration of the APP-α-processing. More importantly, further results showed that under the ACAT1 inhibition, the alterations of the PM-FC and the subsequent APP-α-processing are not dependent on the cellular total cholesterol level, confirming that ACAT1 regulates the dynamics of PM-FC. Finally, we revealed that even when the Niemann-Pick-Type C-dependent pathway is blocked, the ACAT1 inhibition still obviously results in the PM-FC increase, suggesting that the ACAT1-dependent pathway is responsible for the shuttling of PM-FC to the intracellular pool. Our data provide a novel insight that ACAT1 which enzymatically regulates the dynamics of PM-FC may play important roles in the human neuronal cells.
Down-regulation of SDF1-α expression in tumor microenvironment is associated with aspirinmediated suppression of the pro-metastasis effect of sorafenib in hepatocellular carcinoma

Sorafenib is considered to be the first-line therapy for advanced hepatocellular carcinoma (HCC). It significantly delays tumor progression time; however, it increases the invasive andmetastatic potential of HCC. Recent studies have shown that aspirin is effective in preventing and treating tumors, and the combination treatment of aspirin and sorafenib significantly suppresses sorafenib-induced intrahepatic metastasis. However, themechanismthroughwhich aspirin suppresses the sorafenib-induced intrahepatic metastasis is still unclear. In this study,we find that sorafenibmarkedly increases stromal-derived factor 1-alpha (SDF1-α) expression in paratumor and intratumor tissues, and aspirin attenuates sorafenibinduced increase of SDF1-α expression in paratumor and intratumor tissues. Further studies show that SDF1-α improves cell invasion potential of HCC cells, and that AMD3100, a specific inhibitor of SDF1-α receptor CXCR4, suppresses the elevated intrahepatic metastatic potential of HCC induced by sorafenib in vivo. Collectively, this study reveals that the sorafenib-induced increase of SDF1-α expression in paratumor and intratumor microenvironments is suppressed by aspirin, which is associated with aspirin-mediated suppression of the pro-metastasis effect of sorafenib in HCC.
Analysis of frequency shifting in seismic signals using Gabor-Wigner transform

A hybrid time-frequency method known as Gabor-Wigner transform (GWT) is introduced in this paper for examining the time-frequency patterns of earthquake damaged buildings. GWT is developed by combining the Gabor transform (GT) and Wigner-Ville distribution (WVD). GT and WVD have been used separately on synthetic and recorded earthquake data to identify frequency shifting due to earthquake damages, but GT is prone to windowing effect and WVD involves ambiguity function. Hence to obtain better clarity and to remove the cross terms (frequency interference), GT and WVD are judiciously combined and the resultant GWT used to identify frequency shifting. Synthetic seismic response of an instrumented building and real-time earthquake data recorded on the building were investigated using GWT. It is found that GWT offers good accuracy for even slow variations in frequency, good time-frequency resolution, and localized response. Presented results confi rm the effi cacy of GWT when compared with GT and WVD used separately. Simulation results were quantifi ed by the Renyi entropy measures and GWT shown to be an adequate technique in identifying localized response for structural damage detection.
Infl uence of dynamic soil-pile raft-structure interaction: an experimental approach

Traditionally seismic design of structures supported on piled raft foundation is performed by considering fi xed base conditions, while the pile head is also considered to be fi xed for the design of the pile foundation. Major drawback of this assumption is that it cannot capture soil-foundation-structure interaction due to fl exibility of soil or the inertial interaction involving heavy foundation masses. Previous studies on this subject addressed mainly the intricacy in modelling of dynamic soil structure interaction (DSSI) but not the implication of such interaction on the distribution of forces at various elements of the pile foundation and supported structure. A recent numerical study by the authors showed signifi cant change in response at different elements of the piled raft supported structure when DSSI effects are considered. The present study is a limited attempt in this direction, and it examines such observations through shake table tests. The effect of DSSI is examined by comparing dynamic responses from fi xed base scaled down model structures and the overall systems. This study indicates the possibility of signifi cant underestimation in design forces for both the column and pile if designed under fi xed base assumption. Such underestimation in the design forces may have serious implication in the design of a foundation or structural element.
Cross-spectral recognition method of bridge deck aerodynamic admittance function

This study proposes a new identifi cation algorithm about the admittance function, which can estimate the full set of six aerodynamic admittance functions considering cross power spectral density functions about the forces and the turbulence components. The method was fi rst numerically validated through Monte Carlo simulations, and then adopted to estimate the aerodynamic admittance of a streamlined bridge deck. The identifi cation method was further validated through a comparison between the numerical calculation and wind tunnel tests on a moving bridge section.
偏头痛的非药物治疗进展

我国偏头痛在普通人群中的发病率已经达到9.3%,为社会经济发展造成了严重的负担。药物仍是治疗偏头痛的主要方法,由于药物存在副作用及禁忌症,且有一定复发率,所以需要更多元化的手段治疗偏头痛。近年来随着对偏头痛发病机制的研究不断深入,神经阻滞、神经刺激、肉毒菌素注射、激痛点治疗等在临床逐步得到重视,也涌现了大量的针对这些方法的临床试验。本文介绍了近年来研究较多的治疗方法及其原理,并总结了研究的不足及发展趋势。
A novel two-stage Lagrangian decomposition approach for refinery production scheduling with operational transitions in mode switching

To address large scale industrial processes, a novel Lagrangian scheme is proposed to decompose a refinery scheduling problem with operational transitions in mode switching into a production subproblem and a blending and delivery subproblem. To accelerate the convergence of Lagrange multipliers, some auxiliary constraints are added in the blending and delivery subproblem. A speed-up scheme is presented to increase the efficiency for solving the production subproblem. An initialization scheme of Lagrange multipliers and a heuristic algorithm to find feasible solutions are designed. Computational results on three cases with different lengths of time horizons and different numbers of orders show that the proposed Lagrangian scheme is effective and efficient.
Improvement of the riboflavin production by engineering the precurso biosynthesis pathways in Escherichia coli

3,4-Dihydroxy-2-butanone 4-phosphate (DHBP) and GTP are the precursors for riboflavin biosynthesis. In this research, improving the precursor supply for riboflavin production was attempted by overexpressing ribB and engineering purine pathway in a riboflavin-producing Escherichia coli strain. Initially, ribB gene was overexpressed to increase the flux from ribulose 5-phosphate (Ru-5-P) to DHBP. Then ndk and gmk genes were overexpressed to enhance GTP supply. Subsequently, a R419L mutation was introduced intopurA to reduce the flux from IMP to AMP. Finally, co-overexpression of mutant purF and prs genes further increased riboflavin production. The final strain RF18S produced 387.6 mg riboflavin ? L~(-1) with a yield of 44.8 mg riboflavin per gram glucose in shake-flask fermentations. The final titer and yield were 72.2% and 55.6% higher than those of RF01S, respectively. It was concluded that simultaneously engineering the DHBP synthase and GTP biosynthetic pathway by rational metabolic engineering can efficiently boost riboflavin production in E. coli.
一体式软硬输尿管镜治疗输尿管下段结石并髋关节畸形一例报告

讨论严重髋关节畸形合并尿路结石患者,因采取截石位困难,是经尿道输尿管镜取石术的禁忌证[1]。本例患者既往有髋关节畸形,并有对侧肾切除、患侧输尿管切开取石术史,手术风险高,再次开放手术的难度较大。耻骨上膀胱穿刺途径解决了因截石位困难、尿道狭窄等导致经尿道人路手术困难的问题,使微创治疗输尿管结石合并截石位困难成为可能。我们认为采用经膀胱穿刺路径配合一体式软硬输尿管镜处理此类患者,克服了经尿道人路时输尿管开口变形、 角度大、位置高等难题,具有更大的操作空间和灵活性。一体式软硬输尿管镜以硬镜方式接近输尿管开口,符合泌尿外科医师操作习惯,利用末端可弯曲软镜可以克服角度限制, 进人输尿管开口并到达结石处,与输尿管软镜相比具有更好的可操作性,且容易掌握。
土壤管理与可持续利用——献给2015国际土壤年及《中国农业科学》创刊55周年

土壤是地球自然体,是地球上所有生态系统的自然支撑和生物屏障,调节着地球表层系统过程,并为全人类提供生态系统服务。人类首先利用土壤于农业生产,“民以食为天,食以土为本”,自古以来认定土壤是农业生产的基石,是粮食安全的保障。土壤管理是保障农业可持续发展的重要基础措施,而可持续土壤管理是通过良好土地利用方式和培育管理措施定向提升土壤质量,进而保障和提高土壤的生产能力——作物产量和质量,并改善生态系统服务,促进环境和生态安全。
Crystal Structure and Antifungal Activities of a New Zn(II) Complex Based on Triadimenol

A new Zn(II) complex, [ZnL_2Br_2] (L = triadimenol) was synthesized by the reaction of ZnBr_2 with the commercial fungicide of triadimenol, then characterized by elemental analysis, IR spectroscopy and single-crystal X-ray diffraction. The crystal structure shows that the complex[ZnL_2Br_2] crystallizes in orthorhombic, Pnam space group with a = 11.263(2), b = 8.4478(15), c =36.125(7) A, V = 3437.2(11) A~3, Z = 4, C_(28)H_(36)Br_2Cl_2N_6O_4Zn, M_r = 816.72, D_c = 1.578 g/cm~3, F(000)= 1648, μ = 3.236 mm~(–1), the final R = 0.0388 and wR = 0.0879 for 2399 observed reflections with I > 2σ(I). The central metals adopt square plane coordination geometry. And intermolecular hydrogen bonds connect Zn(II) into a one-dimensional chain. In addition, the title complex and triadimenol were screened for antifungal activities against four selected fungi using the mycelial growth rate method. The results indicate that the complex synthesized shows better antifungal activities than the ligand triadimenol.
Complete Condensation of Zero Range Process in Fitness Networks

In current paper we study the so-called "complete condensation" of zero range process on the fitness network. It is found that under the high temperature limit, the condensation behavior on the fitness model converges to that of the scale-free network, as expected. However, at some temperatures below the critical temprature of Bose- Einstein condensate phase on the fitness network, the complete condensation occurs as well for some values of δ > δ_c, which is impossible on scale-free network according to the criterion.