mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Mechanochemically sulfured FeS_(1.92) as stable and efficient heterogeneous Fenton catalyst

Fenton reaction is one of most promising approaches for efficient removal of various robust organic pollutants in wastewater, however it faces several intrinsic challenges such as acidic condition, sludge waste and sensitive to sulfide-containing compound. Here we reported a novel FeS_(1.92) as an efficient and sulfide resistant heterogeneous Fenton catalyst under mild condition. This novel FeS_(1.92) was facilely prepared through a mechanochemical synthesis of mackinawite (FeS) with sulfur powder (S) by ball milling. The sulfured mackinawite (FeS_(1.92)) exhibits high performance in activating H_2O_2 to generate hydroxyle radicals for organic waste remediation. Furthermore, this FeS_(1.92) based heterogeneous Fenton catalyst is highly sulfide resistant and shows improved performance for degrading sulfide-containing organic pollutants. This study provides an effective mechanochemical approach to fabricate heterogeneous Fenton catalysts for sulfide-containing wastewater treatment.
Synthesis of ACE tricyclic systems of daphnicyclidin A and dehy-droxymacropodumine A

The synthesis of the ACE tricyclic system of daphnicyclidin A and dehydroxymacropodumine A are developed. The key reactions include an efficient aldol reaction to introduce chiral fragment 33 for further construction of piperidine ring B and seven-membered ring C, a nucleophilic addition of lithium pentene to aldehyde for installation of ring E, and a photocatalytic decarboxylation conjugate addition to construct ring C.
Dual-functional Se/Fe complex facilitates TRAIL treatment against resistant tumor cells via modulating cellular endoplasmic reticulum stress

Tumor cell resistance is one of the big hurdles limiting the therapeutic efficacy of tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL)-based cancer treatment. Therefore, the development of a safe and effective sensitizer agent is greatly desired for optimizing TRAIL therapy. Herein, we successfully developed a Se/Fe complex with low toxicity to highly effectively inhibit tumor cells proliferation and migration capabilities through down-regulating ER stress related selenoproteins. Furthermore, it could more efficiently damage tumor spheroids with good penetration capability. More importantly, it could synergize with TRAIL treatment to induce the robust generation of reactive oxygen species (ROS), downregulating ER stress related selenoproteins for triggering tumor cells apoptosis in extrinsic and intrinsic signaling pathways. Taken together, this study provides a potential chemo-drug and sensitizer agent to improve the therapeutic efficacy of TRAIL-based cancer treatment.
Hyperbranched polymer micelles with triple-stimuli backbone-breakable iminoboronate ester linkages

Hyperbranched polymers have attracted increasing interests due to their unique structure-related advantages and have been utilized as drug carriers for controlled delivery. However, it is still challenging to prepare multi stimuli-responsive hyperbranched polymers to sense and response the complex yet delicate changes in physiological environment. Herein, we propose a triple-stimuli backbone-breakable hyperbranched polymer (HBP(OEG-IB)), which is prepared via the convenient iminoboronate multicomponent reaction of α,ω-di(1,2-diol)s oligo(ethylene glycol), tris(3-aminopropyl)amine and 2-formylphenylboronic acid. Upon the stimulation of CO_2, lactic acid and glutathione, micelles formed by HBP(OEG-IB) could be disrupted via the dissociation of iminoboronate ester bond to subsequent release incorporated camptothecin (CPT). Cell experiments show that the HBP(OEG-IB) is non-toxic but can enhance the therapeutic effect of CPT thanks to the effect of the protonated tertiary amino groups. The demonstration made in this work can enrich the design of responsive HBPs and can be readily applied to other systems with tunable responsive properties and functions.
Blocking the defect sites on ultrathin Pt nanowires with Rh atoms to optimize the reaction path toward alcohol fuel oxidation

Anodic electrocatalyst plays the core role in direct alcohol fuel cells (DAFCs), while traditional Pt-catalysts suffer from limited catalytic activity, high over potential and severe CO poisoning. Herein, by selectively depositing Rh atoms on the defective-sites of Pt nanowires (NWs), we developed a new Pt@Rh NW electrocatalyst that exhibited enhanced electrocatalytic performance for both methanol oxidation (MOR) and ethanol oxidation (EOR). Both cyclic voltammetry (CV) and in-situ infrared spectroscopy revealed that the presence of Rh atoms suppressed the generation of poisonous intermediates and completely oxidized alcohols molecule into CO_2. Atomic resolusion spherical aberration corrected high-angle annular dark field scanning transmission electron microscopy (CS-HAADF-STEM) and energy-dispersive X-ray spectroscopy (EDS) mapping analysis revealed that Rh atoms were primarily deposited on the defective sites of Pt NWs. Meanwhile, the presence of Rh atoms also modified the electronic state of Pt atoms and therefore lowered the onset potential for alcohols oxidation potential. This work gives the first clear clue on the role of the defective sites of Pt nanocatalyst poisoning, and propose that selectively blocking these sites with trace amount of Rh is an effective strategy in designing advantageous electrocatalysts.
纤毛黏液结节性乳头状肿瘤/细支气管腺瘤概念的提出、诊断与生物学行为

国内外有关纤毛黏液结节性乳头状肿瘤(ciliated muconodular papillary tumor,CMPT)/细支气管腺瘤(bronchiolar adenoma,BA)的报道不断增加,但限于条件和对文献的解读,缺乏深入的研究工作与讨论,尚未形成自己的观点。本期报道的2例均显示典型的CMPT/BA形态学及免疫表型特征,可以确诊。国内外有许多相关病例报道,值得参阅和深入探究。鉴于此,结合笔者遇到的一些病例和文献复习作如下评述。
经济内循环为主条件下技术创新的路径选择

“加快形成以国内大循环为主体、国内国际双循环相互促进的新发展格局”,这是中央针对国际形势变化作出的重大决策。根据这一决策,我国技术创新与产业发展的路径也应当做适当的选择和调整。
胰岛素过敏并皮下脂肪萎缩及外源性胰岛素自身免疫综合征一例

报道1例成人隐匿性自身免疫性糖尿病(LADA)患者在胰岛素治疗过程中罕见地同时出现胰岛素过敏、皮下脂肪萎缩及外源性胰岛素自身免疫综合征,导致胰岛素难以有效控制血糖,通过逐一对上述各个胰岛素相关自身免疫反应进行诊断、管理,取得良好治疗效果。
Sustainable Blends of Poly(propylene carbonate) and Stereocomplex Polylactide with Enhanced Rheological Properties and Heat Resistance

Sustainable blends of poly(propylene carbonate) (PPC) and stereocomplex polylactide (sc-PLA) were prepared by melt blending equimolar poly(L-lactic acid) (PLLA) and poly(D-lactide acid) (PDLA) with PPC to form sc-PLA crystals in situ in the melt blending process. Differential scanning calorimetry analysis revealed that only sc-PLA, no homo-crystallization of PLLA or PDLA, formed in the PPC matrix as the sc- PLA content was more than 10 wt%. Very intriguingly, scanning electronic microscopy observation showed that sc-PLA was evenly dispersed in the PPC phase as spherical particles and the sizes of sc-PLA particles did not obviously increase with increasing sc-PLA content. As a consequence, the rheological properties of PPC were greatly improved by incorporation of sc-PLA. When the sc-PLA content was 20 wt%, a percolation network structure was formed, and the blends showed solid-like behavior. The sc-PLA particles could reinforce the PPC matrix, especially at a temperature above the glass transition temperature of PPC. Moreover, the Vicat softening temperature of PPC/sc-PLA blends could be increased compared with that of neat PPC.
乳腺癌保乳术联合靶向术中放疗并发症的危险因素分析

回顾性分析82例行保乳术联合靶向术中放疗的乳腺癌患者的临床资料。37例(45.1 %)患者发生并发症,无3 ~4级晚期放射性毒性反应。单因素分析发现围手术期使用抗凝药、适配器≤3 cm、术中放疗时间>20 min、化疗是导致总体并发症的可能危险因素(P<0.1);多因素Logistic回归分析发现围手术期使用抗凝药(P = 0.039)、适配器≤3 cm(P =0.002)是总体并发症的独立危险因素,围手术期使用抗凝药(P= 0.032)、年龄≤50岁(P=0.005)分别是皮肤水肿和色素沉着的独立危险因素。我们认为对于具有并发症危险因素的患者,更加严密的手术操作、必要的药物预防可能能够在一定程度上减轻不适,提高靶向术中放疗的满意度。
消化道肿瘤中自噬与免疫调节的研究进展

最近研究表明,自噬通过调节免疫细胞的功能来调控免疫反应,因此自噬抑制剂与免疫治疗结合可能为我们提供一种有前景的消化道肿瘤治疗策略。本文就自噬的机制、自噬对免疫系统的调节和自噬在消化道肿瘤免疫治疗中的潜在作用进行综述。
Mental health support to staff in a major hospital in Milan(Italy)during the COVID-19 pandemic:a framework of actions

To the Editor,As of 31 March 2020,more than 100000 cases of coronavirus disease 2019(COVID-19)have been confirmed in Italy.Progressive mitigation measures have been introduced by the Italian government since 9 March 2020 to undermine and break the virus transmission chain.However,the COVID-19-associated hospitalisation rate in Lombardy,the epicentre of the outbreak,has risen since the late days of February 2020,by 30% each day,and it is only very recently that it slowed down to 5% daily,which still translates to 500 new patients every day who are in absolute need of hospital care.This has put enormous pressure on healthcare providers and hospitals,up to the point where departments and daily shifts have been assigned in either of the following two categories:COVID-19 and non-COVID-19.In Policlinico,one of the most relevant university hospitals in Milano,the entire organisation has been transformed in less than 2 weeks,moving from 900 inpatient beds with 18 intensive care to 110 intensive and subintensive beds and more than 200 COVID-19 beds,thus completely reorganising the wards.
High-Performance Aqueous Zinc-Manganese Battery with Reversible Mn~(2+)/ Mn~(4+) Double Redox Achieved by Carbon Coated MnO_x Nanoparticles

There is an urgent need for low-cost,high-energy-density,environmentally friendly energy storage devices to fulfill the rapidly increasing need for electrical energy storage.Multi-electron redox is considerably crucial for the development of high-energy-density cathodes.Here we present highperformance aqueous zinc-manganese batteries with reversible Mn~(2+)/ Mn~(4+) double redox.The active Mn~(4+) is generated in situ from the Mn~(2+)-containing MnO_x nanoparticles and electrolyte.Benefitting from the low crystallinity of the birnessite-type MnO_2 as well as the electrolyte with Mn~(2+) additive,the MnO_x cathode achieves an ultrahigh energy density with a peak of 845.1 Wh kg~(-1) and an ultralong lifespan of 1500 cycles.The combination of electrochemical measurements and material characterization reveals the reversible Mn~(2+)/ Mn~(4+) double redox(birnessite-type MnO_2 ↔ monoclinic MnOOH and spinel ZnMn_2O_4 ↔ Mn~(2+) ions).The reversible Mn~(2+)/ Mn~(4+) double redox electrode reaction mechanism offers new opportunities for the design of low-cost,high-energy-density cathodes for advanced rechargeable aqueous batteries.
A Review on Nano-/Microstructured Materials Constructed by Electrochemical Technologies for Supercapacitors

The article reviews the recent progress of electrochemical techniques on synthesizing nano-/microstructures as supercapacitor electrodes.With a history of more than a century,electrochemical techniques have evolved from metal plating since their inception to versatile synthesis tools for electrochemically active materials of diverse morphologies,compositions,and functions.The review begins with tutorials on the operating mechanisms of five commonly used electrochemical techniques,including cyclic voltammetry,potentiostatic deposition,galvanostatic deposition,pulse deposition,and electrophoretic deposition,followed by thorough surveys of the nano-/microstructured materials synthesized electrochemically.Specifically,representative synthesis mechanisms and the state-of-the-art electrochemical performances of exfoliated graphene,conducting polymers,metal oxides,metal sulfides,and their composites are surveyed.The article concludes with summaries of the unique merits,potential challenges,and associated opportunities of electrochemical synthesis techniques for electrode materials in supercapacitors.
The Principle of Introducing Halogen Ions Into β-FeOOH: Controlling Electronic Structure and Electrochemical Performance

Coordination tuning electronic structure of host materials is a quite effective strategy for activating and improving the intrinsic properties.Herein,halogen anion( X~-)-incorporated β-FeOOH(β-FeOOH(X),X = F~-,Cl~-,and Br~-) was investigated with a spontaneous adsorption process,which realized a great improvement of supercapacitor performances by adjusting the coordination geometry.Experiments coupled with theoretical calculations demonstrated that the change of Fe-O bond length and structural distortion of β-FeOOH,which is rooted in halogen ions embedment,led to the relatively narrow band gap.Because of the strong electronegativity of X~-,the Fe element in β-FeOOH(X)s presented the unexpected high valence state(3 + δ),which is facilitating to adsorb SO_3~(2-) species.Consequently,the designed β-FeOOH(X)s exhibited the good electric conductivity and enhanced the contact between electrode and electrolyte.When used as a negative electrode,the β-FeOOH(F) showed the excellent specific capacity of 391.9 F g~(-1) at 1 A g~(-1) current density,almost tenfold improvement compared with initial β-FeOOH,with the superior rate capacity and cyclic stability.This combinational design principle of electronic structure and electrochemical performances provides a promising way to develop advanced electrode materials for supercapacitor.
Intercalating Ultrathin MoO_3 Nanobelts into MXene Film with Ultrahigh Volumetric Capacitance and Excellent Deformation for High-Energy-Density Devices

The restacking hindrance of MXene films restricts their development for high volumetric energy density of flexible supercapacitors toward applications in miniature,portable,wearable or implantable electronic devices.A valid solution is construction of rational heterojunction to achieve a synergistic property enhancement.The introduction of spacers such as graphene,CNTs,cellulose and the like demonstrates limited enhancement in rate capability.The combination of currently reported pseudocapacitive materials and MXene tends to express the potential capacitance of pseudocapacitive materials rather than MXene,leading to low volumetric capacitance.Therefore,it is necessary to exploit more ideal candidate materials to couple with MXene for fully expressing both potentials.Herein,for the first time,high electrochemically active materials of ultrathin MoO_3 nanobelts are intercalated into MXene films.In the composites,MoO_3 nanobelts not only act as pillaring components to prevent restacking of MXene nanosheets for fully expressing the MXene pseudocapacitance in acidic environment but also provide considerable pseudocapacitive contribution.As a result,the optimal M/MoO_3 electrode not only achieves a breakthrough in volumetric capacitance(1817 F cm~(-3) and 545 F g~(-1)),but also maintains good rate capability and excellent flexibility.Moreover,the corresponding symmetric supercapacitor likewise shows a remarkable energy density of 44.6 Wh L~(-1)(13.4 Wh kg~(-1)),rendering the flexible electrode a promising candidate for application in high-energy-density energy storage devices.
A Universal Principle to Accurately Synthesize Atomically Dispersed Metal-N_4 Sites for CO_2 Electroreduction

Atomically dispersed metal-nitrogen sites-anchored carbon materials have been developed as effective catalysts for CO_2 electroreduction( CO_2ER),but they still suffer from the imprecisely control of type and coordination number of N atoms bonded with central metal.Herein,we develop a family of single metal atom bonded by N atoms anchored on carbons(SAs-M-N-C,M = Fe,Co,Ni,Cu) for CO_2ER,which composed of accurate pyrrole-type M-N_4 structures with isolated metal atom coordinated by four pyrrolic N atoms.Benefitting from atomically coordinated environment and specific selectivity of M-N_4 centers,SAs-Ni-N-C exhibits superior CO_2ER performance with onset potential of -0.3 V,CO Faradaic efficiency(F.E.) of 98.5% at -0.7 V,along with low Tafel slope of 115 mV dec-1 and superior stability of 50 h,exceeding all the previously reported M-N-C electrocatalysts for CO_2-to-CO conversion.Experimental results manifest that the different intrinsic activities of M-N_4 structures in SAs-M-N-C result in the corresponding sequence of Ni >Fe >Cu >Co for CO_2ER performance.An integrated Zn-CO_2 battery with Zn foil and SAs-Ni-N-C is constructed to simultaneously achieve CO_2-to-CO conversion and electric energy output,which delivers a peak power density of 1.4 mW cm~(-2) and maximum CO F.E.of 93.3%.
Torque Characteristics of High Torque Density Partitioned PM Consequent Pole Flux Switching Machines With Flux Barriers

Unique double salient structure of Permanent Magnet Flux Switching Machines (PMFSM) with both Concentrated Armature Winding (CAW) and Permanent Magnet (PM) on stator attract researcher's interest for high speed brushless application when high torque density (T(den)) and power density (P_(den)) are the primal requirements. However, despite of stator leakage flux, high rare-earth PM usage, PMFSM is subjected to slot effects due to presence of both PM and CAW in stator and partial saturation due to double salient structure which generates cogging torque (T(cog)), torque ripples (T(rip)) and lower average torque (T(avg) ). To overcome aforesaid demerits, this paper presents Partitioned PM (PPM) Consequent Pole Flux Switching Machine (PPM-CPFSM) with flux barriers to enhance flux modulation, curtail PM usage and diminish stator leakage flux which reduces slotting effects and partial saturation to ultimately reduces T(cog) and T(rip). In comparison with the existing state of the art, proposed PPM-CPFSM reduces 46.53% of the total PM volume and offer T(avg) higher up to 88.8%, suppress T(rip) maximum up to 24.8%, diminish T(cog) up to 22.74% and offer 2.45 times T(den) and P_(den). Furthermore, torque characteristics of proposed PPM-CPFSM is investigated utilizing space harmonics injection i.e. inverse cosine, inverse cosine with 3rd harmonics and rotor pole shaping techniques i.e., eccentric circle, chamfering and notching. Detailed electromagnetic performance analysis reveals that harmonics injection suppressed T(cog) maximum up to 83.5%, T(rip) up to 40.72% at the cost of 4.71% T(avg). Finally, rotor mechanical stress analysis is utilized for rotor withstand capability and 3D-FEA based Coupled Electromagnetic-Thermal Analysis (CETA) for thermal behavior of the developed PPM-CPFSM. CETA reveals that open space along PPM act as cooling duct that improve heat dissipation.
Investigation of Influence of Winding Structure on Reliability of Permanent Magnet Machines

Winding is an important part of the electrical machine and plays a key role in reliability. In this paper, the reliability of multiphase winding structure in permanent magnet machines is evaluated based on the Markov model. The mean time to failure is used to compare the reliability of different windings structure. The mean time to failure of multiphase winding is derived in terms of the underlying parameters. The mean time to failure of winding is affected by the number of phases, the winding failure rate, the fault-tolerant mechanism success probability, and the state transition success probability. The influence of the phase number, winding distribution types, multi three-phase structure, and fault-tolerant mechanism success probability on the winding reliability is investigated. The results of reliability analysis lay the foundation for the reliability design of permanent magnet machines.
Robust Position Anti-Interference Control for PMSM Servo System With Uncertain Disturbance

Aiming to suppress the influence of uncertain disturbances in the drive control of permanent magnet synchronous machines (PMSM), such as the parameter uncertainties and load disturbance, a robust anti-interference control for the angular position tracking control of a PMSM servo system has been proposed in this paper. During the position tracking, uncertain system disturbances being regarded as a lumped unknown term will be online observed by a nonlinear disturbance observer (NDOB), of which the influence will consequently be counteracted by a robust backstepping compensator (RBC). The asymptotical stability of proposed control scheme is analyzed and designed according to the Lyapunov stability criterion, and its convergence against the system uncertain disturbance is verified on a prototype PMSM servo platform and shows good performance in rotor angular position tracking and anti-interference.
Multiobjective Electric Machine Optimization for Highest Reliability Demands

This article is about illustrating a workflow for incorporating reliability measures to typical electric machine design optimization scenarios. Such measures facilitate comparing designs not only for rated conditions, but also allow to analyze their performance in the presence of unevitable tolerances. Consequently, by additionally considering reliability or robustness as objectives compared to conventional optimization scenarios, designs featuring low parameter sensitiveness can be obtained. The analysis of the design's reliability as part of solving optimization problems involves a significant increase in required numerical evaluations. To minimize the associated prolongation of the runtime, an approach featuring a design of experiments based reduction of required computations and a consequent surrogate modeling technique is presented here. After successful training, the metamodel can be applied for fast evaluating lots of different parameter combinations. A test problem is defined and analyzed. Based on the observed findings, the necessity of incorporating robustness evaluations to machine design optimization becomes evident. In addition, the derived models allow for studying the impact of any toleranceaffected parameter on the machine performance in detail. This facilitates further beneficial studies, as for instance the analysis of selected changes of tolerance levels rather than a general minimization of the respective ranges which usually is associated with high production cost.
Guaranteeing the Fault Transient Performance of Aerospace Multiphase Permanent Magnet Motor System: an Adaptive Robust Speed Control Approach

To enhance the fault transient performance of aerospace multiphase permanent magnet synchronous motor (PMSM) system, an adaptive robust speed control is proposed regardless of the phase open-circuit (OC) and short-circuit (SC) fault in this paper, which can be applied for both the redundant motor system and fault tolerant motor system. For aerospace multiphase PMSM system, besides external load disturbance and system parameter perturbation, there inevitably exists the electromagnetic torque ripple in fault transient process, which can degrade the system performance and even cause the system instability. To cope with this issue, the electromagnet torque ripple of the multiphase PMSM system in fault transient process is first analyzed. Then, by considering the electromagnet torque fluctuation caused by fault transient as a system uncertainty, a novel adaptive robust speed control scheme is proposed, while the adaptive law is constructed to emulate the total system uncertainty bound, which include the load disturbance, the parameter variation, and the electromagnetic torque fluctuation due to fault transient. The resulting control can ensure the speed control performance even in fault transient process regardless of the uncertainty, in which no prior estimation of the uncertainty bound is required. In addition, the proposed adaptive robust speed control is demonstrated by a six-phase PMSM experimental platform. The novelty of this research is to explore a novel adaptive robust speed control to strengthen the fault tolerance performance of multiphase PMSM system even in fault transient process, which requires no prior estimation of the uncertainty bound.