mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
遗传性凝血因子Ⅶ缺乏一例

患儿男,40 d.因皮肤穿刺处渗血不止,间断呕血39 d住院.患儿为第1胎第2产,足月剖宫产,生后无窒息.生后第2天哭声低弱,反应差,阵发性抽搐,呕吐,呕吐物呈咖啡色,量多时带有新鲜血丝.诊断为"新生儿缺氧缺血性脑病",给予综合治疗.治疗期间皮肤穿刺部位渗血不止,反复呕吐,呕吐物为含血丝的咖啡色胃内容物.……
关于根管解剖的命名问题(一)

根管的解剖较复杂,自1842年Carabelli研究以来,有以作者根据各自的观察所得,对根管系统各部分进行了命名,在文献中出现了许多名称:主根管、主髓管;副根管;副髓管;侧枝根管、旁侧根管、根管侧支、管间吻合、管间交通支、横管、水平管;根尖细枝、根尖分叉、根尖三角洲;副根管、侧副根管,有的将主根管及其主要分支称为大管系统,其它则称为小管系统,等等.……
火柴杆制作小楔子的临床应用

我们用火柴杆制作小楔子,经临床10余年的应用,效果较好,介绍如下. 1材料 来源于火柴厂未蘸磷的火柴杆. 2制作方法 取火柴杆一根,将其按需要剪成1.5～2 cm长的断端,用刀片把杆子的一端削成扁尖形,另一端尾部沿着杆的周围刻出一条小凹槽,再用4号黑丝线双股栓在凹槽内,线留1.5 cm长,打个结,火柴杆便制成了小楔子,一次制作厚薄长短不一的若干个小楔子,置甲醛箱内消毒贮存备用.……
两种方法检测人血清中抗水痘抗体的比较

水痘-带状疱疹病毒(VZV)抗体检测的方法主要有膜抗原免疫荧光抗体检测试验(FAMA)和ELISA等.FAMA是传统的"金标准",但操作繁琐,时间较长,ELISA简便易行,可自动化操作,时间短,适于大规模筛选样本.目前市售ELISA试剂盒均采用全病毒抗原包被,敏感性较差,只有个别疫苗制造公司开发了糖蛋白ELISA(gpELISA)试剂盒,但尚未商业化.随着水痘疫苗的广泛应用,需要对现有检测方法进行评价.为此,本文借对水痘疫苗进行临床评价之机,对两种方法进行比较.……
贵州省玉米专家系统的开发与应用

介绍了基于GIS技术的贵州玉米专家系统的主要功能、实现技术与应用示范,详细讨论了在系统开发与推广应用中的指导思想、关键技术和应用效果.系统内含大量的科学试验数据、研究调查资料和贵州省农业领域专家的丰富知识,包含品种选择、播前决策、肥料运筹、田间管理、病虫害与缺素诊断、生产效益分析等决策功能,具有综合、系统、准确的特点.
麦套玉米叶片数及其应用

通过对麦田套种玉米叶片生长及不同展开叶期追肥对产量影响的研究.结果表明:麦套玉米的叶片总数与单作玉米相同或相差1片,小麦收获时,套种玉米展开叶2～3片,可见叶4～5片为适宜套种时间;麦套玉米应重施攻秆肥,叶龄指数40～50为适宜追肥期.本研究结果可作为黄淮海地区麦田套种玉米栽培管理的参考.
妊娠合并系统性红斑狼疮患者自身抗体变化对围产结局的影响

系统性红斑狼疮(SLE)是一类病因尚未明了的多系统、多脏器受损的自身免疫性疾患.其在细胞免疫和体液免疫方面均呈明显变化,以致多种免疫学指标异常.SLE患者的多种自身抗体的变化与围产结局的关系已备受关注.现就其研究现状综述如下.……
玉米杂交种吉东6号的选育技术报告

吉东6号是吉林省吉东种业有限责任公司农科所以自选系D01为母本,外引系丹598为父本组配而成的玉米杂交种.经过5年的各级试验示范结果表明,在吉林省两年区域试验中该品种比对照新铁10平均增产14.2%,吉东6号幼苗早发性强,植株生长健壮,高抗玉米各种病害,抗倒伏,综合农艺性状优良,适应性强,一般产量都在8 670.1 kg/hm2以上.
超级玉米指标及选育模式

基于目前玉米科研动态和生产需求,提出超级玉米概念和五项育种指标:①超高产.15 000 kg/hm2或比主栽对照品种增产20%;②优质.达到国标二级以上;③广适.适宜我国几大玉米主产区;④多抗.抗多种病虫害和多种不利生态因子;⑤易制种.制种产量达7 500 kg/hm2,易保芽率和质量.并提出在产量要素构成上有中穗型密植和大穗型稀植等模式;除利用现有的核心种质和杂优模式,参照目前的郑单958、农大108、豫玉22等成功的杂优模式外,还需进一步进行种质扩增、创新和探索新的杂优模式.
组织工程与创伤医学

组织工程是近年来逐渐发展起来的一项新型医疗技术.其基本原理是应用细胞生物学和工程学的原理,将体外培养扩增后具有生物学活力及特定功能的细胞与可降解生物支架材料复合,在体内或体外再造组织或器官,用以修复或改善损伤组织或器官的结构与功能,最终形成有活力的正常组织或器官,达到真正意义上的生物学重建[1].
胰头部无功能性胰岛细胞瘤超声表现1例

患者女,33岁.因体检发现胰头部占位2个月来我院手术治疗,患者无任何临床症状及体征.CT诊断为胰腺占位(性质待定).超声检查:胰头下缘部见向下生长的实质不均质低回声团块,边界清,形如"哑铃状",内部回声不均匀且可见小囊腔,肿块大小约 74 mm×40 mm(图1),内见少量点状彩色血流信号(图2),肿块与肠系膜上静脉分界欠清,肠系膜上静脉肿块侧管壁显示不清(图3).超声诊断:胰头部占位(胰岛细胞瘤,胰腺癌).术中所见:肿块位于胰头部,大小 5 cm×6 cm×9 cm,无明显包膜,压迫但未侵及肠系膜上静脉,行胰十二指肠扩大根治术.术后病理诊断(包括免疫学检查):无功能性胰岛细胞瘤,组织学图像无恶性依据,周围淋巴结均为阴性.
生态农业"三维"复合系统的运行机制研究

在充分论述了生态农业内涵的基础上,从系统论的角度,考察了生态农业"三维"复合系统的结构、特征及其运行机制,包括内部制衡机制和外部管理体制,生态农业"三维"复合系统的制约、调控和演化原理,生态经济市场运行机制等方面.
欠发达地区生态农业发展的思考

发展生态农业是解决"三农"问题的重要手段之一.欠发达地区发展生态农业有环境优势、资源优势、人力资源优势,并且形成了多种生态农业模式,有了一定的基础,但要保证生态农业的可持续发展,必须建立生态补偿机制,政策性农业保险,加强对生态农业的投入,加快土地的合理流转,大力发展农产品加工业.
茶叶珠宝青针增香工艺改进

珠宝青针是由宿松县二郎镇铜铃村开发制成的省级优质茶.珠宝青针虽在外形、汤色、滋味上具有独特的品质,但因其香气低闷,未能参加部级以上评比.对其制作工艺进行了改进,根据糖胺化合物与水分和温度的关系,在一定范围内提高叶温,能促进糖胺化合物的形成,从而提高茶叶香气,改善珠宝青针品质.
物质依赖中渴求的功能磁共振研究进展

物质依赖中的渴求(craving)是物质依赖者对特定物质或经历的一种内在的强烈渴望感,为复吸的主要原因之一[1,2].由于物质依赖者常明知使用成瘾物质会在认知、行为和生理等方面带来明显的问题,但却仍继续使用,从而导致对成瘾物质的耐受性增加、戒断症状和冲动性觅药行为[3],因此,以渴求为突破口,探讨成瘾机制及复吸干预策略已成为当今研究热点.既往对渴求脑机制的探讨主要借助于动物模型,20世纪90年代随功能磁共振(functional magnetic resonance imaging,fMRI)的出现,开始了对清醒人脑进行从语言、记忆、认知甚至情感等领域的观察,为活体探讨渴求这一心理现象提供了新的契机.现就fMRI成像的方法、原理,以及在物质依赖中渴求的研究做一综述.
应激相关精神障碍的人身损害赔偿案司法精神病鉴定辨析

在当前的人身损害诉讼需要进行司法精神病鉴定的案例中,大致包括两类情况,第一类是因交通事故、工伤和其他生活事件造成的脑实质性损伤,出现脑器质性精神障碍;第二类是无脑实质性损伤而出现功能性精神障碍.其中在功能性精神障碍中,应激相关精神障碍是人身损害赔偿案鉴定中常见的一种精神障碍,也是在评定纠纷事件中最为复杂的案例,因此有必要对该类障碍鉴定的相关问题进行深入探讨.
维他灵2号在"黔单11号"玉米上的应用效果

研究了不同生育期喷施植物生长调节剂维他灵2号对黔单11号玉米株高及产量的影响.结果表明:在拔节期、大喇叭口期喷施维他灵2号对黔单11号株高有明显降低作用,并且保持产量不变.从株型外观、抗病性以及调节剂用量试验等方面来看,在拔节期喷施维他灵2号具有较好的防倒效果.
20%移栽灵乳油防治烟草黑胫病的研究

对20%移栽灵乳油防治烟草黑胫病的效果进行了田间对比试验研究.结果表明:20%移栽灵乳油1 500倍对烟草黑胫病的防效可达80%以上,且药效稳定,持效期长,建议在安徽省烟叶生产中示范推广使用.
43%好力克SC防治棉花枯(黄)萎病的研究

研究了43%好力克SC防治棉花枯(黄)萎病的效果及施药方法.结果表明:在棉花定植活棵后、现蕾始期、花蕾期及结铃盛期,用43%好力克SC 3000～4000倍液+多功能营养素叶面喷雾或8000倍液+营养素根部浇灌,接力防治3～4次,效果较好.
抗虫棉花铃期天敌对害虫的控制效应

对抗虫棉田间害虫、天敌各物种种类的数量和空间分布进行了调查统计,并对害虫、天敌各物种种间的生态位关系进行了分析.结果表明:抗虫棉田间的天敌生态位最大,且天敌物种的生态位多大于害虫物种的生态位,抗虫棉田天敌对害虫的控制效应较为显著.
杂交水稻红莲优6号示范表现及其高产栽培技术

杂交水稻红莲优6号是由武汉大学培育的高产、优质的杂交中籼新品种.该品种产量具有超级稻的潜力,米质达到国标优质标准;对纹枯病田间抗性强,中感白叶枯病,易感稻曲病.2002年通过湖北省农作物品种审定委员会审定.2003年在安徽望江示范推广,笔者分析了该品种的产量和农艺性状表现,提出了相应的关键栽培技术.
品种区域试验数据质量的判断

通过对小麦品种区域试验数据的统计和分析,阐述了在田间试验中采取一系列措施降低试验误差的重要性.结论是:在田间试验中只有严格按照试验规程最大限度地降低试验误差,才能得出准确可靠的试验数据,从而保证试验质量.
施氮量对杂交稻丰优香占物质运转与品质形成的影响

丰优香占是一个优质杂交籼稻组合.在大田条件下,以汕优63为对照,研究了不同施氮量处理对丰优香占干物质的积累、运转及品质特性形成的影响.结果表明:兼顾高产与优质,提高氮肥利用率,187.5～225 kg/hm2的施氮量是正常情况下丰优香占较为适合的一个肥料运筹指标.
钬激光在泌尿外科中的应用

钬激光(holmium:YAG laser)是目前众多外科手术用激光中较新的一种,为脉冲式激光,工作介质是包含在钇铝石榴石晶体中的钬.钬激光波长为2100nm,可通过软光纤传送,特别适合泌尿外科的腔内手术,并具有以下特性:①穿透深度浅,组织穿透度＜0.5mm,可用于精确的外科切割和止血;②高能脉冲式.钬激光在泌尿外科常用于尿道和输尿管狭窄切开、浅表性移行细胞癌切除、膀胱颈切开、前列腺切除和碎石,是一种多用途的外科激光.现就钬激光在泌尿外科的临床应用情况综述如下.
固相载体法提取胰腺癌患者血清循环DNA的研究

近年研究发现,肿瘤患者血清或血浆中存在较高水平的肿瘤源性DNA(亦称循环DNA),正常人血清或血浆中的含量甚微(<10ng),因而对其遗传学改变进行检测,对肿瘤的诊断、鉴别和治疗预后等具有重要意义[1].然而,血清中含有的大量蛋白质、糖类、脂质等均可影响微量循环DNA的提取,而分离纯化则是准确检测的关键步骤.本研究采用全血基因组DNA提取的异硫氰酸胍-硅胶法[2]与高灵敏度的SYBR GreenⅠ染色技术,建立了一种可提取血清或血浆DNA的固相载体法,并用于胰腺癌患者血清循环DNA检测.
胃癌术后双侧附睾转移一例报告

患者,男,65岁.因双侧阴囊坠痛1个月余入院.3年前因胃癌在外院行胃癌根治术,术后定期复查.未见复发或转移.1个月前感双侧阴囊坠胀、疼痛,渐加重,左侧显著.B超提示双侧睾丸鞘膜积液.查体见左侧阴囊肿大约5 cm×4 cm×4 cm,轻微触痛,张力较大,睾丸及附睾均触不清,右侧阴囊肿大不明显,附睾有结节,无触痛,睾丸无异常.
昆虫生长调节剂和生物农药防治韭蛆田间药效试验

对3种昆虫生长调节剂和2种生物农药对韭蛆田间防效进行了初步评价.春季试验结果表明,10%高渗烟碱水剂1000倍液防效最好,达70.0%以上;70%灭蝇胺可湿性粉剂3000倍液和0.3%印楝素乳油1000倍液次之;而5%卡死克乳油800倍液和5%抑太保乳油1000倍液的防效较差.将春季试验药效较好的3种农药用于秋季田间试验,结果表明,10%高渗烟碱水剂1000倍液和70%灭蝇胺可湿性粉剂3000倍液防效较好,特别是10%高渗烟碱水剂的防效达到79.8%,几乎与40%辛硫磷乳油1000倍液相当.0.3%印楝素乳油1000倍液的防效较差,仅为69.2%.
长效与短效促性腺激素释放激素激动剂用于超促排卵周期降调节的探讨

目的:探讨长效与短效促性腺激素释放激素激动剂(GnRH-a)在体外受精-胚胎移植(IVF-ET)超促排卵降调节中的差异.方法:将51个IVF-ET周期患者分为A、B两组均行长方案控制超促排卵,A组26例应用长效GnRH-a1.875mg降调节,B组25例应用短效GnRH-a0.05mg降调节.结果:A组rFSH用量及用药时间显著大于B组,(P＜0.05).两组周期第3天内分泌水平、获卵数、卵裂率、受精率、临床妊娠率差异均无显著性(P＞0.05).结论:在超排卵周期降调节中长效GnRH-a较短效GnRH-a对卵巢抑制更深且rFSH用量及用药时间更多.
莲子草--B型烟粉虱的一种重要杂草寄主

B型烟粉虱(Bemisia tabaci)是本世纪初随种苗调运而传入浙江临海市的一种外来入侵物种.室内饲养表明,烟粉虱在临海市能发生11代,以伪蛹在棚室内越冬.烟粉虱主要危害瓜类、茄果类蔬菜及花卉.成、若虫群集在叶背,除直接刺吸叶片汁液,致使植株衰弱矮小外,若虫和成虫还分泌蜜露诱发煤污病,发生严重时叶片呈黑色,严重影响光合作用,导致作物产量和品质下降.由于该虫繁殖能力强,发生数量多,防治上颇感困难,现已成为大棚蔬菜和花卉产业最具潜在威胁的一种新害虫.
10例非产后期乳腺炎X线表现

乳腺炎为哺乳期的一种常见病,而非哺乳期乳腺炎由于症状不典型,容易被忽视或被误诊为其他疾病甚至肿瘤.本研究回顾性分析我院经手术病理证实的10例非产后期乳腺炎的钼靶X线表现及临床资料 ,旨在提高诊断水平.
浅谈高赖氨酸玉米育种技术路线与方法

高赖氨酸玉米是指蛋白质中富含赖氨酸的玉米.早在1935年,美国人就已从玉米自然突变体中分离出高赖氨酸突变系,从中发现了基因O1、O2、fl1和fl2,之后又成功地把O2基因转移到硬粒角质型的优良材料中,克服了先前高赖氨酸玉米产量低、软质胚乳的缺点,育成了一系列籽粒性状与普通玉米相似的高赖氨酸杂交种。
气浮+SBR工艺处理屠宰废水

采用气浮+SBR工艺处理屠宰废水.在进水CODCr为1200～1850 mg/L的条件下,经该工艺处理后出水CODCr在90mg/L以下,各项指标均达到<污水综合排放标准>(GB8978-1996)一级标准,出水还可部分回用.
太极推手锻炼与补钙对绝经女性骨密度的影响

目的:探讨太极推手锻炼加钙剂补充综合疗法对绝经女性骨密度的影响.方法:选择绝经女性64例(年龄57.21±3.41岁),按绝经年龄随机分为4组,太极推手锻炼加钙剂补充为A组,单行太极推手锻炼为B组,单行补钙为C组,不进行有计划锻炼和钙剂补充为D组.治疗实验期6个月,且在其前、后及再跟踪6个月后分别采用双能骨密度仪对受试者腰椎L2-4进行骨密度测定;骨密度变化采用t检验,组间综合疗效比较采用χ2检验.结果:A、B、C、D 4组骨密度在实验后的变化率分别为2.037%、1.361%、0.378%、-0.874%,A组增加明显,与D组比较具有显著性差异(P＜0.05);停止实验6个月后,4组骨密度降低率分别为0.665%、0.671%、0.964%、0.881%,各组自身前后比较,C组降低显著(P＜0.05).组间综合疗效比较,A组优于B组(P＜0.01),B组优于C组(P＜0.001).结论:太极推手锻炼和钙剂补充均能帮助绝经女性防止骨量丢失,增加骨密度,太极推手锻炼加补钙的作用优于单纯太极推手锻炼,同时太极推手锻炼在停训后一段时间内有维持骨量的效应.
间歇性低氧暴露对小鼠自由基代谢的影响

本实验选用40只雄性ICR封闭群小鼠,随机分为4组:对照组、低氧暴露组、运动组、运动+低氧组,每组10只.4周训练结束后,取心、脑、完整的腓肠肌,测试各组织MDA含量及SOD活性.实验结果提示:(1)间歇性低氧暴露提高了心肌组织的SOD水平,同时MDA水平下降,表明心肌抗氧化能力提高,有利于在长时间运动中保持正常供血功能.(2)间歇性低氧暴露提高骨骼肌组织SOD活性和降低MDA含量,表明间歇性低氧暴露可有效提高骨骼肌抗氧化能力.(3)间歇性低氧暴露可提高脑组织对过氧化脂质的清除能力和SOD活性,对于延缓中枢疲劳有意义.
铜陵矿区水系沉积物中重金属污染及潜在生态危害评价

重金属潜在生态危害指数是评价沉积物化学参数生物毒性大小的有效手段.我们于2002年11月和2003年11月对铜陵矿区水系进行了沉积物采样,结合水样分析结果,将不同区段河流沉积物中重金属的含量与国标值进行比较分析,并用潜在生态危害指数法对矿区水系的重金属污染和生态危害进行了评价.
督脉电针与神经干细胞移植联合应用促进全横断脊髓损伤组织产生内源性神经生长活性物质的研究

我们先前的研究发现,督脉电针与神经干细胞(NSCs)移植联合应用能够促进全横断损伤脊髓的结构和部分功能修复.但不清楚这是否通过督脉电针促进受损伤脊髓组织产生一些内源性神经生长活性物质,参与全横断损伤脊髓的结构和部分功能修复.
系统性红斑狼疮合并血行播散型结核一例报道

系统性红斑狼疮(SLE)是免疫系统的常见病,由于其免疫功能低下,可并发细菌、病毒、结核等感染.现就本院曾收治的1例SLE合并血行播散型结核病例的诊治过程作一回顾分析.……
中药活血化瘀治疗慢性肾炎血尿临床观察

慢性肾炎的进展和恶化与肾小球内高凝状态有密切关系.笔者将我院肾活检后经泼尼松、雷公藤治疗2个月以上,仍有镜下血尿者44例分为两组,对照组继续行泼尼松、雷公藤治疗,治疗组在对照组治疗的基础上加用中药活血化瘀基本方辨证加味治疗,根据肾活检肾间质的病变程度判断治疗效果,取得较满意疗效.现介绍如下。
中医药的继承与创新--读《陈可冀医学选集--七十初度》

自步入医门以来,每每拜读陈可冀院士的文章,总是被其博精的医学造诣和不折不扣的科研精神所折服,但多为断续篇章阅读,因此仅限于点滴感受而不能系统把握其学术思想的内涵.今有幸得陈可冀院士赠我的导师王米渠教授<陈可冀医学选集--七十初度>(以下简称<选集>)一书,才使我有机会深刻领悟陈可冀院士的学术思想.导师强调他之所以崇拜他的老师,根本在于陈可冀院士对血瘀证与老年病的研究成果.本文为在导师的指导下,读<选集>的三点心得体会。
无害化钻井液体系的研究与应用

为解决钻探施工作业过程中和完井后钻井液对环境污染问题,进行了无害化钻井液体系的研究.室内研究和现场试验表明,从污染的源头上控制有毒产品的使用,用环保型处理剂配制无害化钻井液体系,既可满足钻井工程需要,又能显著降低现场对钻井废水处理的难度,大大减轻钻井施工作业过程中的环保压力,从而实现钻井清洁生产.
DCS系统在闪电停运离心泵恢复启动方面的应用

离心泵为石油化工生产装置中的主要动力设备,应用十分广泛,离心泵的连续稳定运行是生产装置高效平稳运行的根本保障.中原油气高新股份有限公司第二气体处理厂利用DCS系统解决闪电停运离心泵的瞬间恢复启动问题,极大程度地降低了闪电对轻烃装置连续生产造成的影响.
天然石墨在室温离子液体电解液中的嵌脱锂性质

室温离子液体是现代化学中的先进液态功能材料之一,用作锂离子电池电解液具有导电性好、不燃烧和易回收等突出优点,是未来动力锂离子电池理想的电解液组分[1].然而,由于离子液体的造价高、粘度大且与电极活性物质的浸润性差,将其用于锂离子电池还需要大量的基础研究工作[2]. 本文研究了天然石墨负极材料在室温离子液体电解液中的电化学嵌脱锂性质,选用多种有机电解液添加剂改善了离子液体电解液与石墨类负极材料的相容性,报道了一种在锂离子电池中有应用前景的室温离子液体电解液体系.……
骨骼肌失神经萎缩的细胞分子生物学研究进展

周围神经损伤后,骨骼肌因神经的营养作用丧失及自身废用而发生萎缩,出现一系列形态结构、生理生化及代谢功能等方面的改变.而神经损伤后,骨骼肌萎缩的防治一直是周围神经外科的一大难题,当骨骼肌萎缩发展到不可逆阶段将导致神经修复手术的失败.因此,进一步探索不同时段失神经后萎缩肌肉的形态结构、生理、生化变化以及它们之间的相互关系,为寻找检测肌肉萎缩程度的方法和更好的防治具有重要临床意义.
Autonomous Dual Active Power-frequency Control in Power System with Small-scale Photovoltaic Power Generation

Active power control of the photovoltaic (PV) power generation system is a promising solution to regulate frequency fluctuation in a power system with high penetration of renewable energy.This paper proposes an autonomous active power control of a small-scale PV system for supporting the inertial response of synchronous generators and power-frequency control.In the proposed control approach,an effective grid frequency regulation scheme is realized using slow- and fast-frequency responses.A low-pass filter based frequency measurement is used for slow-frequency response,while direct frequency measurement is used for fast-frequency response.The designed dual droop characteristic-based control is shaped to achieve a smooth transition between slow- and fast-frequency responses.The performance of the proposed control approach is demonstrated for serious disturbance scenarios,i.e.,considerable power-load imbalance and generation trip.In the powerload imbalance test scenario,the proposed control approach works properly within the normal frequency deviation region even when the frequency deviation exceeds that region occasionally.In the generation trip test,the frequency deviation is mitigated quickly,and the employed droop control is smoothly transferred from the slow- to fast-frequency responses.
Expression and possible role of Smad3 in postnecrotizing enterocolitis stricture

Objective To investigate the expression of Smad3 (mothers against decapentaplegic homolog 3) protein in postnecrotizing enterocolitis stricture and its possible mechanism of action. Methods We used immunohistochemistry to detect the expression characteristics of Smad3 and nuclear factor kappa B (NF-κB) proteins in human postnecrotizing enterocolitis stricture. We cultured IEC-6 (crypt epithelial cells of rat small intestine) in vitro and inhibited the expression of Smad3 using siRNA technique. Quantitative PCR,western blotting, and ELISA were used to detect the changes in transforming growth factor-β1 (TGF-β1), NF-κB, tumor necrosis factor-a (TNF-α), vascular endothelial growth factor (VEGF), and zonula occludens-1 (ZO-1) messenger RNA (mRNA) and protein expressions in IEC-6 cells. CCK8 kit and Transwell cellular migration were used to detect cell proliferation and migration. Changes in epithelial-mesenchymal transition (EMT) markers (Ecadherin and vimentin) in IEC-6 cells were detected by immunofluorescence technique. Results The results showed that Smad3 protein and NF-κB protein were overexpressed in narrow intestinal tissues and that Smad3 protein expression was positively correlated with NF-κB protein expression. After inhibiting the expression of Smad3 in IEC-6 cells, the mRNA expressions of NF-κB, TGF-β1,ZO-1,and VEGF decreased, whereas the mRNA expression of TNF-α did not significantly change. TGF-β1,NF-κB, and TNF-α protein expressions in IEC-6 cells decreased, whereas ZO-1 and intracellular VEGF protein expressions increased. IEC-6 cell proliferation and migration capacity decreased. There was no significant change in protein expression levels of EMT markers E-cadherin and vimentin and also extracellular VEGF protein expression. Conclusions We suspect that the high expression of Smad3 protein in postnecrotizing enterocolitis stricture may promote the occurrence and development of secondary intestinal stenosis. The mechanism may be related to the regulation of TGF-β1,NF-κB, TNF-α, ZO-1, and VEGF mRNA and protein expression. This may also be related to the ability of Smad3 to promote epithelial cell proliferation and migration.
Addressing barriers to evidence-based medicine in pediatric surgery: an introduction to the Canadian Association of Paediatric Surgeons Evidence-Based Resource

Background Pediatric surgical practice lags behind medicine in presence and use of evidence, primarily due to time constraints of using existing tools that are not specific to pediatric surgery, lack of sufficient patient data and unstructured pediatric surgery training methods. Method We developed, disseminated and tested the effectiveness of an evidence-based resource for pediatric surgeons and researchers that provides brief, informative summaries of quality-assessed systematic reviews and meta-analyses on conflicting pediatric surgery topics. Results Responses of 91 actively practicing surgeons who used the resource were analysed. The majority of participants found the resource useful (75%), improved their patient care (66.6%), and more than half (54.2%) found it useful in identifying research gaps. Almost all participants reported that the resource could be used as a teaching tool (93%). Conclusion Lack of awareness of the resource is the primary barrier to its routine use, leading to potential calls for more active dissemination worldwide. Users of the Canadian Association of Paediatric Surgeons Evidence-Based Resource find that the summaries are useful, identify research gaps, help mitigate multiple barriers to evidence-based medicine, and may improve patient care.
Fine-Tuning Contact via Complexation for High-Performance Organic Solar Cells

For organic optoelectronic devices,precise tuning of the electrical property of both active layers and interfaces is crucial to achieve enhanced device performance.Herein,we developed a facile method using complexation to modify the work function and energy levels of cathode contact layers in organic solar cells (OSCs) to achieve suitable work function and energy levels while retaining relatively good conductivity.Compared with the control devices with neat (N,N-dimethyl-ammonium N-oxide)propyl perylene diimide (PDINO) contacts,the tris(pentafluorophenyl)borane (BCF)-complexed PDINO cathode contacts showed enhanced power conversion efficiencies (PCEs),which is independent of the composition of the active layer.More specifically,single-junction OSCs employing PDINO cathode contact with 2 wt % BCF-additive achieved an average PCE of 17.7%.Based on experimental data and theoretical modeling,we found that the boron cores of BCF coordinate with the amino N-oxide terminal substituent of PDINO after generating BCF-H_2O/methanol complexes.BCF segments with a strong electron-withdrawing property can effectively reduce the energy levels of the PDINO-BCF complex,and thus enhance device PCE when it is used as a cathode contact in OSCs.This strategy can be extended to other types of photovoltaic devices,photodetectors,and light-emitting diodes.
Mapping sensitive vegetation communities in mining eco-space using UAV-LiDAR

Near earth sensing from uncrewed aerial vehicles or UAVs has emerged as a potential approach for fine-scale environmental monitoring. These systems provide a cost-effective and repeatable means to acquire remotely sensed i mages in unprecedented spatial detail and a high signal-to-noise ratio. It is increasingly possible to obtain both physiochemical and structural insights into the environment using state-of-art light detection and ranging (LiDAR) sensors integrated onto UAVs. Monitoring sensitive environments, such as swamp vegetation in longwall mining areas, is essential yet challenging due to their inherent complexities. Current practices for monitoring these remote and challenging environments are primarily ground-based. This is partly due to an absent framework and challenges of using UAV-based sensor systems in monitoring such sensitive environments. This research addresses the related challenges in developing a LiDAR system, including a workflow for mapping and potentially monitoring highly heterogeneous and complex environments. This involves amalgamating several design components, including hardware integration, calibration of sensors, mission planning, and developing a processing chain to generate usable datasets. It also includes the creation of new methodologies and processing routines to establish a pipeline for efficient data retrieval and generation of usable products. The designed systems and methods were applied to a peat swamp environment to obtain an accurate geo-spatialised LiDAR point cloud. Performance of the LiDAR data was tested against ground-based measurements on various aspects, including visual assessment for generation LiDAR metrices maps, canopy height model, and fine-scale mapping.
《黄帝内经》饮食养生理论研究

《黄帝内经》最早记载了中医饮食养生方论,奠定了中医饮食养生的理论基础。《素问·上古天真论篇》明确提出中医养生基本原则和方法为“法于阴阳,和于术数,食饮有节,起居有常,不妄作劳”,而饮食养生在诸多养生方法中居于首位。《黄帝内经》是以“中和”思想为核心,以阴阳、五行学说为基础,以气血、阴阳、脏腑、经络理论为根本,以饮食的作用、饮食养生基本原则、饮食养生主要方法及病家饮食禁忌等为框架,构建的中医饮食养生理论体系,对后世中医饮食养生理论与实践的发展有着重要影响。
1例产后坏死性子宫肌炎影像学表现

讨论坏死性子宫肌炎起病隐匿、进行性发展,多发生于子宫动脉栓塞术及子宫压迫缝合术后,或因产后胎盘胎膜残留继发感染;影像学表现为子宫肌层呈片状T1低信号、T2高信号,CT可见子宫肌层内低密度影,坏死区多无明显强化,其内气体进行性增多伴脓肿形成。本例剖宫产后行压迫缝合术,使子宫血流减少;之后为止血而栓塞双侧子宫动脉,此时子宫尚未能充分形成侧支循环,致使其缺血,肌层进行性坏死并继发感染。鉴别诊断:①妊娠物残留,血清人绒毛膜促性腺激素明显升高,宫腔内不均匀肿块,增强后可见强化;②宫腔内血块,信号和密度多变,且无明显强化,子宫壁结构层次正常。
不同加工方法对薤白活性成分及抗氧化活性的影响

目的探究不同加工方法对薤白活性成分含量及抗氧化活性的影响。方法将新鲜薤白分别进行冻干、50℃烘干、煮后50℃烘干,测定3种加工品中皂苷、多糖、氨基酸、黄酮、生物碱、挥发油含量,以及其醚提物、醇提物、水提物对DPPH、ABTS、OH自由基的清除能力。结果3种加工方法对薤白中的皂苷、多糖、氨基酸和挥发油含量有显著影响,对黄酮和生物碱含量无明显影响。烘干品中皂苷含量最高,冻干品中多糖含量最高,冻干品中挥发油含量与鲜品接近,煮后烘干品中3类成分含量均降低。3种加工品的醚、醇、水提取物分别对OH、ABTS、DPPH自由基显示较强的清除能力,但煮后烘干品提取物的清除率最低。结论不同加工方法会影响薤白的成分含量及抗氧化活性,本实验可为合理有效利用薤白资源提供参考。
手性芳烃钌(II)催化不对称C-H键活化研究

近年来,钌(II)催化不对称C-H键活化取得了重要进展.基于钌(II)催化剂的结构,可通过三种策略实现催化不对称的C-H键活化:(1)利用手性瞬态导向基策略.2019年,密西西比州立大学Cui和中山大学汪君团队分别独立利用该策略实现了钌(II)催化的分子内C-H键活化.(2)使用手性酸配体.2021年,浙江大学史炳锋、哥廷根大学Ackermann、北海道大学Yoshino和Matsunaga课题组分别以手性羧酸为配体,实现了钌(II)催化分子间或分子内不对称C-H键活化.(3)设计手性芳烃配体.虽然手性环戊二烯(Cp)配体已被广泛地应用于Co,Rh,Ir催化的不对称C-H键活化反应,但对于手性芳烃钌(II)催化剂,可能由于制备困难,且芳烃配体易与金属钌(II)解离,使得手性芳烃钌(II)催化的不对称C-H键活化研究面临很大的挑战,至今尚无报道.因此开发一种具有良好适用性、可调性和稳定性的手性芳烃钌(II)催化剂,实现不对称C-H键活化具有重要理论意义和潜在的应用价值.
Developing a robust correlation for prediction of sweet and sour gas hydrate formation temperature

There are numerous correlations and thermodynamic models for predicting the natural gas hydrate formation condition but still the lack of a simple and unifying general model that addresses a broad ranges of gas mixture. This study was aimed to develop a user-friendly universal correlation based on hybrid group method of data handling (GMDH) for prediction of hydrate formation temperature of a wide range of natural gas mixtures including sweet and sour gas. To establish the hybrid GMDH, the total experimental data of 343 were obtained from open articles. The selection of input variables was based on the hydrate structure formed by each gas species. The modeling resulted in a strong algorithm since the squared correlation coefficient (R2) and root mean square error (RMSE) were 0.9721 and 1.2152, respectively. In comparison to some conventional correlation, this model represented not only the outstanding statistical parameters but also its absolute superiority over others. In particular, the result was encouraging for sour gases concentrated at H_2S to the extent that the model outstrips all available thermodynamic models and correlations. Leverage statistical approach was applied on datasets to the discovery of the defected and doubtful experimental data and suitability of the model. According to this algorithm, approximately all the data points were in the proper range of the model and the proposed hybrid GMDH model was statistically reliable.
Artificial lift system optimization using machine learning applications

Currently, in the oil industry, artificial lift optimization (ALO) systems are dealing with different applications including well monitor and control, reservoir management, production optimization, predictive maintenance, artificial lift, and flow assurance, multiphase pumping systems, etc. The scope of this article is to provide a detailed analysis of ALO and predictive pump maintenance applications using machine learning (ML) and artificial intelligence (AI). The oil and gas industry has experienced a lot of improvements that have impacted the businesses and economies associated with the market in recent times. Issues such as unplanned shutdown time and failure of equipment cause a huge impact on many corporations especially with the current fluctuations in hydrocarbon prices. Similarly, advanced modern technologies such as real-time analysis and predictive maintenance are designed to drive ALO systems. This paper covers several applications and techniques in which ML and AI have been applied to optimize hydrocarbon withdrawal from potentially depleted reservoirs that require some external supports to uplift the reservoir fluid from sub surface to surface using artificial lift system. In a nutshell, the applications of AI and ML for the artificial lift selection, their predictive maintenance, equipment malfunctioning detection, etc. using a self-trained system are the main topics of this paper. While reviewing each of these techniques, the workflow is also explained along with the effectiveness of utilizing each application to the current operations.
Data-driven Power Flow Method Based on Exact Linear Regression Equations

Power flow (PF)is one of the most important calculations in power systems. The widely-used PF methods are the Newton-Raphson PF (NRPF)method and the fast-decoupled PF (FDPF)method. In smart grids, power generations and loads become intermittent and much more uncertain, and the topology also changes more frequently, which may result in significant state shifts and further make NRPF or FDPF difficult to converge. To address this problem, we propose a data-driven PF (DDPF)method based on historical/simulated data that includes an offline learning stage and an online computing stage. In the offline learning stage, a learning model is constructed based on the proposed exact linear regression equations, and then the proposed learning model is solved by the ridge regression (RR)method to suppress the effect of data collinearity. In online computing stage, the nonlinear iterative calculation is not needed. Simulation results demonstrate that the proposed DDPF method has no convergence problem and has much higher calculation efficiency than NRPF or FDPF while ensuring similar calculation accuracy.
A Commutation Failure Prediction and Mitigation Method

The mitigation of commutation failure (CF)depends on the accuracy of CF prediction. In terms of the large error of the existing extinction angle (EA)calculation during the fault transient period, a method for CF prediction and mitigation is proposed. Variations in both DC current and overlap angle (OA)are considered in the proposed method to predict the EA rapidly. In addition, variations in critical EA and the effect of firing angle (FA)on both DC current and OA are considered in the proposed method to obtain the accurate FA order for the control system. The proposed method can achieve good performance in terms of CF mitigation and reduce reactive consumption at the inverter side when a fault occurs. Simulation results based on the PSCAD/EMTDC show that the proposed method predicts CF rapidly and exhibits good performance in terms of CF mitigation.