mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Platinum-group Mineral (PGM) and Base-metal Sulphide (BMS) Inclusions in Chromitites of the Zedang Ophiolite, Southern Tibet, China and their Petrogenetic Significance

Voluminous platinum-group mineral (PGM) inclusions including erlichmanite (Os,Ru)S_2, laurite (Ru,Os)S_2, and irarsite (Ir,Os,Ru,Rh)AsS, as well as native osmium Os(Ir) and inclusions of base metal sulphides (BMS), including millerite (NiS), heazlewoodite (Ni_3S_2), covellite (CuS) and digenite (Cu_3S_2), accompanied by native iron, have been identified in chromitites of the Zedang ophiolite, Tibet. The PGMs occur as both inclusions in magnesiochromite grains and as small interstitial granules between them; most are less than 10 μm in size and vary in shape from euhedral to anhedral. They occur either as single or composite (biphase or polyphase) grains composed solely of PGM, or PGM associated with silicate grains. Os-, Ir-, and Ru-rich PGMs are the common species and Pt-, Pd-, and Rh-rich varieties have not been identified. Sulfur fugacity and temperature appear to be the main factors that controlled the PGE mineralogy during crystallization of the host chromitite in the upper mantle. If the activity of chalcogenides (such as S, and As) is low, PGE clusters will remain suspended in the silicate melt until they can coalesce to form alloys. Under appropriate conditions of ?S_2 and ?O_2, PGE alloys might react with the melt to form sulfides-sulfarsenides. Thus, we suggest that the Os, Ir and Ru metallic clusters and alloys in the Zedang chromitites crystallized first under high temperature and low ?S_2, followed by crystallization of sulphides of the laurite-erlichmanite, solid-solution series as the magma cooled and ?S_2 increased. The abundance of primary BMS in the chromitites suggests that ?S_2 reached relatively high values during the final stages of magnesiochromite crystallization. The diversity of the PGE minerals, in combination with differences in the petrological characteristics of the magnesiochromites, suggest different degrees of partial melting, perhaps at different depths in the mantle. The estimated parental magma composition suggests formation in a suprasubduction zone environment, perhaps in a forearc.
探索语音识别技术的前世今生

自动语音识别技术(Automatic Speech Recognition-ASR)是一种实现从“声音”到“文字”转换的技术,通过将人的语音直接转换成相应的文本以便计算机进行理解和产生相应的操作,并最终实现人与机器之间的自然语音交互。语音识别就好比“机器的听觉系统”,让机器通过识别和理解,能够把语音信号转变为相应的文本或命令,下面简要回顾语音识别技术的发展历程。
智能手机行业生态文明的发展战略

智能手机作为信息时代的时尚引领者,正处在发展的快车道。据市场调查机构公布的数据,全球智能手机出货量在2015年已达14亿多部,同比增长10%以上。而中国在其中占有举足轻重的地位:中国生产的智能手机在2015年接近14亿部,成为全球智能手机绝对的主产地;同时,中国市场销售的智能手机超过4亿部,成为全球智能手机最大的单一市场。尤其引人注目的是,中国品牌智能手机继续保持强劲的发展势头,2015年的出货量占全球的比重超过四成,总量接近苹果、三星两大巨头之和,在全球十大智能手机品牌中占据七席,为“中国制造”赢得了声誉,成为中国制造业实施由“制造大国”迈向“制造强国”的战略转型的排头兵。
Distribution and transportation of mercury from glacier to lake in the Qiangyong Glacier Basin, southern Tibetan Plateau, China

The Tibetan Plateau is home to the largest aggregate of glaciers outside the Polar Regions and is a source of fresh water to 1.4 billion people. Yet little is known about the transportation and cycling of Hg in high-elevation glacier basins on Tibetan Plateau. In this study, surface snow, glacier melting stream water and lake water samples were collected from the Qiangyong Glacier Basin. The spatiotemporal distribution and transportation of Hg from glacier to lake were investigated. Significant diurnal variations of dissolved Hg (DHg) concentrations were observed in the river water, with low concentrations in the morning (8:00 am-14:00 pm) and high concentrations in the afternoon (16:00 pm-20:00 pm). The DHg concentrations were exponentially correlated with runoff, which indicated that runoff was the dominant factor affecting DHg concentrations in the river water. Moreover, significant decreases of Hg were observed during transportation fromglacier to lake.DHg adsorption onto particulates followed by the sedimentation of particulate-bound Hg (PHg) could be possible as an important Hg removal mechanism during the transportation process. Significant decreases in Hg concentrations were observed downstream of Xiao Qiangyong Lake, which indicated that the high-elevation lake systemcould significantly affect the distribution and transportation of Hg in the Qiangyong Glacier Basin.
Microcystin accumulation and biochemical responses in the edible clam Corbicula leana P. exposed to cyanobacterial crude extract

We investigated the accumulation and effects of cyanobacterial crude extract (CCE) containing microcystins (MCs) on the edible clam Corbicula leana P. Toxic effects were evaluated through the activity of antioxidant and detoxification enzymes: catalase (CAT), superoxide dismutase (SOD), and glutathione-S-transferases (GSTs) from gills, foot, mantle and remaining soft tissues. Clams were exposed to CCE containing 400 μg MC-LR_(eq)/L for 10 days and were then kept in toxin-free water for 5 days. Clam accumulated MCs (up to 3.41 ± 0.63 μg/g dry weight (DW) of unbound MC and 0.31 ± 0.013 μg/g DW of covalently bound MC). Detoxification and antioxidant enzymes in different organs responded differently to CCE during the experiment. The activity of SOD, CAT, and GST in the gills and mantle increased in MC-treated clams. In contrast, CAT and GST activity was significantly inhibited in the foot and mostly only slightly changed in the remaining tissues. The responses of biotransformation, antioxidant enzyme activity to CCE and the fast elimination of MCs during depuration help to explain how the clam can survive for long periods (over a week) during the decay of toxic cyanobacterial blooms in nature.
Structural and metabolic responses of microbial community to sewage-borne chlorpyrifos in constructed wetlands

Long-term use of chlorpyrifos poses a potential threat to the environment that cannot be ignored, yet little is known about the succession of substrate microbial communities in constructed wetlands (CWs) under chlorpyrifos stress. Six pilot-scale CW systems receiving artificial wastewater containing 1 mg/L chlorpyrifos were established to investigate the effects of chlorpyrifos and wetland vegetation on the microbial metabolism pattern of carbon sources and community structure, using BIOLOG and denaturing gradient gel electrophoresis (DGGE) approaches. Based on our samples, BIOLOG showed that Shannon diversity (HV) and richness (S) values distinctly increased after 30 days when chlorpyrifos was added. At the same time, differences between the vegetated and the non-vegetated systems disappeared. DGGE profiles indicated that HVand S had no significant differences among four different treatments. The effect of chlorpyrifos on the microbial community was mainly reflected at the physiological level. Principal component analysis (PCA) of both BIOLOG and DGGE showed that added chlorpyrifos made a difference on test results. Meanwhile, there was no difference between the vegetation and no-vegetation treatments after addition of chlorpyrifos at the physiological level. Moreover, the vegetation had no significant effect on the microbial community at the genetic level. Comparisons were made between bacteria in this experiment and other known chlorpyrifos-degrading bacteria. The potential chlorpyrifos-degrading ability of bacteria in situ may be considerable.
Lipogenesis in myoblasts and its regulation of CTRP6 by AdipoR1/Erk/PPARγ signaling pathway

The induced lipogenesis and its regulation in C2C12 myoblasts remain largely unclear. Here, we found that the cocktail method could significantly induce lipogenesis through regulating lipid metabolic genes and Erk1/2 phosphorylation in myoblasts. Meanwhile, the expression and secretion of CTRP6 were increased during ectopic lipogenesis. Moreover, CTRP6 knockdown down-regulated the levels of lipogenic genes and phosphorylated Erk1/2 (p-Erk1/2) in the early lipogenic stage, whereas up-regulated p-Erk1/2 in the terminal differentiation. Interestingly, the effect of CTRP6 siRNA was attenuated by U0126 (a special p-Erk1/2 inhibitor) in myoblasts. Furthermore, AdipoR1, not AdipoR2, was first identified as a receptor of CTRP6 during the process of mitotic clonal expansion. Collectively, we suggest that CTRP6 mediates the ectopic lipogenesis through AdipoR1/Erk/PPARγ signaling pathway in myoblasts. Our findings will shed light on the novel biological function of CTRP6 during myoblast lipogenesis and provide a hopeful direction of improving meat quality of domestic animal by lipogenic regulation in skeletal muscle myoblasts.
乌鲁木齐地区89例皮肤软组织感染金黄色葡萄球菌分子特征研究

金黄色葡萄球菌是人类重要机会致病菌,也是目前引起院内感染的首要病原菌,是引起皮肤软组织感染最主要的致病菌,特别是20世纪80年代后社区获得性耐甲氧西林金黄色葡萄球菌在全球范围的流行,其与皮肤软组织感染的发生紧密相关。对金黄色葡萄球菌特别是耐甲氧西林金黄色葡萄球菌(methicillin resistant Staphylococcus aureus, MRSA)进行分子分型是研究分析该病原菌传播、致病、进化的重要手段。金黄色葡萄球菌能够分泌毒力、酶类等大量致病因子以及细菌自身组分,使其具有较强的致病性。因此对金黄色葡萄球菌及MRSA的分子特征、耐药谱及致病因子的研究可以为阻断其在院内及社区内传播,为临床医师治疗其感染提供理论基础。
血清抗苗勒管激素方法学比较及女性正常参考区间建立

抗苗勒管激素(anti-Mullerian hormone, AMH)是近10年来在生殖健康领域最受关注的激素指标,它是由2个相对分子质量72 000的二聚体单体组成,通过二硫键连接的同源二聚体糖蛋白,属于转化生长因子-β(TGF-β)超家族成员,女性AMH的合成来源于卵泡发育早期阶段的卵泡颗粒细胞,是卵泡成熟调控的至关重要的激素。AMH可以反映卵巢窦状卵泡和窦前卵泡的数量(卵巢储备),评估卵巢功能。测定血清AMH水平在评价性腺功能状态和相关疾病中有着重要意义。虽然常规激素检测项目(促卵泡激素、促黄体生成激素、雌二醇等)在临床上已广泛应用,但这些激素均随月经周期变化而变化,而AMH在不同生理周期中表达稳定,因此检测更为方便,在临床上的应用前景更为广泛。
民航飞行员星状玻璃体变性一例

星状玻璃体变性在民航飞行员中并不多见,可能与飞行员定期的身体检查和航医的健康监控有关,发病率较普通人群低。本例患者平素身体健康,无自觉症状,并否认相关病史。裂隙显微灯和眼底照相检查发现左眼玻璃体内散在的大量白色闪光样混浊小点,无玻璃体液化,并且根据眼B超的特征改变符合星状玻璃体变性的诊断,考虑该飞行员目前视功能正常,结论:飞行合格。建议该飞行员3?6个月复査1次视野和对比敏感度,便于体检医生对其病情进行监测和干预。
南航广州地区餐饮具消毒状况分析

餐饮具消毒作为食品安全中的关键环节,其消毒质量是否达标直接影响到飞行机组、运行人员的健康,甚至影响到飞行安全。因此,在地面餐饮单位进行餐饮具消毒质量监测,并采取改善性举措显得尤为必要。笔者通过对中国南方航空股份有限公司(以下简称南航)广州地区10家餐饮单位餐饮具的消毒效果进行检测,并分析不同季节、种类和消毒方法消毒合格率的差异,现将结果报告分析如下。
飞行员特发性震颤一例

特发性震颤(essential tremor, ET)是一组原因不明的常染色体显性遗传疾病,可发生于各个年龄段,约30%有家族遗传史,30岁后患病率增加,50岁后明显增加。男性居多,为神经内科常见疾病之一。震颤是本病常见症状,发病多从双手开始,逐渐累及上肢。多为良性发展,对生活影响不大,但对精细操作影响甚大。据报道约有17.5%病人导致了生活、工作困难。严重者影响身体、心理健康,甚至导致残废。我军现役飞行员此病报道极少,对飞行的影响尚待研究。流行病学研究表明此病常与其他疾病有一定关系,主要是帕金森和偏头痛。有研究报道ET患者偏头痛的发病率较高,偏头痛患者的ET发病率也较高。本例患者2009年有偏头痛史,曾多次住院治疗,可以佐证此结论。该飞行员2008年发病后,5年间没有治疗。2013年3月症状明显后送院治疗,缓解后出院限双座机飞行,无不适症状,未见影响飞行的表现。
棕榈酸帕利哌酮注射液治疗精神分裂症的研究进展

棕榈酸帕利哌酮是一种新型的治疗精神分裂症的长效制剂,具有安全有效、使用方便、患者依从性高等优点。现综述棕榈酸帕利哌酮治疗精神分裂症的疗效、安全性、作用机制及使用方法的研究进展。
光学相干断层扫描评价鞍区占位患者视神经损伤的研究进展

压迫性视神经病变的首要病因是颅内占位性病变,以鞍区最常见,包括垂体腺瘤、颅咽管瘤、脑膜瘤等。占位性病变对视神经产生机械性压迫,许多患者早期因出现视力下降、视野缺损及视神经萎缩等首诊于眼科。目前,视野检查是诊断视路病变的“金标准”,但其是一种主观检查,变异性较大,早期各报道缺乏一致性,且其难以准确地评估患者视功能的预后。随着光学相干断层扫描(optical coherence tomography, OCT)在临床的广泛应用,对压迫性视神经病变患者的相关研究也成为热点。相对于视野检查,OCT具有快速、非接触式、非侵入性、分辨率高、重复性好等优势,通过测量神经纤维厚度和黄斑的体积,早期就能检测出视网膜及视神经结构的损害,敏感性较高;能定量、客观地评价压迫性视神经病变等视神经疾病的损伤情况;而且OCT有助于疾病的鉴别诊断,例如压迫性视神经病变与青光眼性视神经病变,因早期不典型的视野改变,可造成鉴别诊断困难,甚至误诊,OCT在鉴别该两种疾病方面具有一定的优势;因OCT能定量检测,故有助于预测解除压迫后患者的视功能。本文对OCT评价鞍区占位患者视神经损伤方面进行综述分析。
正常压力性脑积水的诊治研究进展

正常压力性脑积水(normal pressure hydrocephalus,NPH)最初是以第一种可治愈的痴呆被报道的。直到1963年,Hakim和Adams才首次将该疾病命名为NPH。在最初的几十年,脑脊液分流的治疗方式因分流技术落后、临床成功率低以及并发症频发,并不被看好。近年来,随着对NPH的诊断和治疗水平的提高,脑脊液分流术的临床成功率达到70% ~ 90%。风险评估的数据还显示,行手术治疗的NPH患者其预后要明显好于非手术治疗的NPH患者。未接受手术治疗的NPH患者生存期仅有几个月甚至更短,而且生命质量也很差。然而,迄今为止,即便找到了对于NPH较为合适的治疗方法,也仅有10% ~ 20%的NPH患者能及时接受针对性治疗。究其原因,主要是NPH难以早期确诊,与其他神经退行性疾病鉴别困难。本文综述了近年来NPH诊治的新进展,以期对NPH相关的临床工作提供帮助。
股前外侧皮瓣修复不同创面的体会:附17例报告

目的总结股前外侧皮瓣修复不同创面体会。方法2009年10月至2015年3月,根据创面部位及临床修复需要,分别采用带蒂顺行、逆行转移以及游离移植的方式修复重建肢体创面缺损及器官外露共17例。手足小腿外伤创面伴骨、肌腱外露7例,修复会阴缺损1例,膝下截肢残端骨外露2例,皮肤慢性溃疡经久不愈4例,胭窝瘢痕挛缩伸膝障碍1例,下咽癌重建1例,颅骨骨外露1例。创面缺损范围:7 cm × 4 cm ~ 23 cm × 12 cm,皮瓣切取大小:8 cm × 5 cm ~ 27 cm × 13 cm。皮瓣游离移植13例、顺行转移1例、逆行转移3例。结果17例皮瓣全部成活,其中2例局部表层皮肤坏死,二期点状植皮修复。患者均获随访,皮瓣外观功能均满意。结论股前外侧皮瓣临床转移方式灵活,可切取面积大,部位隐蔽,不损伤主干血管,切取后不影响肢体功能,是修复创面缺损及器官再造的理想皮瓣。
肾上腺异位甲状腺一例

讨论:肾上腺异位甲状腺是一种较罕见的良性病变,多发生于女性(男女之比为1:9),常无临床症状,一般多在常规体检或异位甲状腺体积明显增大引起压迫等症状,在检查时被发现。自日本学者Tsujimura等1996年首次报道以来,目前国外文献共报道约11例,其中,日本报道了6例,西班牙2例,美国、瑞士及意大利各1例。11例中,男性1例,女性10例。发病年龄为32~67岁(中位年龄50岁),老年多发。其中4例为体检时偶尔发现,2例为下背部或季肋部疼痛行CT检查发现,5例为其他病变(3例)或术前检查(2例)发现,7例原发于左肾上腺,4例右肾上腺。均为囊性病变,常为单房(10例),偶见多房囊肿(1例),直径最大为50 mm,最小为4 mm,表面光滑,似有包膜,囊壁较薄,内壁光滑,常见淡黄色液性内容物。组织学上,囊内壁见扁平或上皮细胞被覆,被覆上皮下见甲状腺样组织,并见甲状腺样滤泡,滤泡腔可见嗜酸性胶质样物。偶见营养不良性钙化、胆固醇结晶及巨噬细胞,滤泡上皮为单层立方上皮,部分区域可见滤泡与肾上腺皮质混杂,通常无肾上腺髓质成分,部分病例囊壁被覆细胞或甲状腺滤泡样细胞可见核重叠,染色质透明,偶见核沟或包涵体,类似甲状腺乳头状癌细胞核,但未见沙砾体;囊肿外壁为纤维组织,偶有平滑肌细胞。免疫组织化学显示:囊肿内壁被覆扁平上皮及甲状腺滤泡上皮细胞,其甲状腺球蛋白、TTF1、 CK(AE1/AE3)、CK7阳性,不表达CK19、降钙素、CK20、嗜铬粒素A、突触素、血小板内皮黏附分子(CD31)、CD34、 FⅧAg、WT1及D2-40,细胞增殖指数(Ki-67)较低(<5%),灶状囊壁被覆细胞表达Galedin-3、HBME1。 Casadei等及Romero-Rojas等应用即时定量PCR法对甲醛固定石蜡包埋的肾上腺异位甲状腺组织进行基因检测,未检出BRAF或KRAS的基因突变。
上下泪小点周鳞状细胞乳头状瘤伴上泪小管炎及结石一例

该患者为高龄女性,本例患者我们经术前检查,手术显微镜下行活检后瘤体完整切除联合泪道内窥镜下排石治疗是行之有效的方法。因为乳头状瘤有易复发、易恶变的特点,我们术中采用活检明确诊断鳞状细胞乳头状瘤后,再确定行上下睑缘完整瘤体切除的手术治疗方案,避免了再次进行治疗性手术,并防止了瘤体的复发。由于通过内镜可以观察到泪道阻塞的部位和管腔情况;另一方面,可通过工作通道直视下进行同步治疗,这样可以使泪道疾病的诊断更为准确精细,而手术方法的选择目的性更强。在对以往单纯激光或探通术后病例检查中发现,常残留白色纤维状物,一端游离,冲洗时通畅,但单凭盲目治疗很难将其去除干净,恢复光滑管腔。而在内镜的直视下,可以清晰地看到泪道管腔内病变特点,将结石、纤维状分泌物配合使用激光和微型电钻,彻底清除,有效地保持了正常管道的通畅,避免泪道黏膜的大面积损伤,可以更好地避免术后瘢痕形成,避免了由于细菌、分泌物易附着可能是术后再阻塞发生的源泉。该患者随访1年均未见复发,泪道冲洗通畅,此类病变行瘤体切除联合泪道内镜下排石治疗是行之有效的方法。嘱患者严格时间随访,一旦有复发倾向或恶变的高风险,尽早治疗处理。
Relationship between Intrauterine Bacterial Infection and Early Embryonic Developmental Arrest

Background: Early embryonic developmental arrest is the most commonly understudied adverse outcome of pregnancy. The relevance of intrauterine infection to spontaneous embryonic death is rarely studied and remains unclear. This study aimed to investigate the relationship between intrauterine bacterial infection and early embryonic developmental arrest. Methods: Embryonic chorion tissue and uterine swabs for bacterial detection were obtained from 33 patients who underwent artificial abortion (control group) and from 45 patients who displayed early embryonic developmental arrest (trial group). Results: Intrauterine bacterial infection was discovered in both groups. The infection rate was 24.44% (11/45) in the early embryonic developmental arrest group and 9.09% (3/33) in the artificial abortion group. Classification analysis revealed that the highest detection rate for Micrococcus luteus in the early embryonic developmental arrest group was 13.33% (6/45), and none was detected in the artificial abortion group. M luteus infection was significantly different between the groups (P < 0.05 as shown by Fisher's exact test). In addition, no correlation was found between intrauterine bacterial infection and history of early embryonic developmental arrest. Conclusions: M luteus infection is related to early embryonic developmental arrest and might be one of its causative factors.
Evaluation of the Prostate Imaging Reporting and Data System for Magnetic Resonance Imaging Diagnosis of Prostate Cancer in Patients with Prostate-specific Antigen <20 ng/ml

Background: The European Society of Urogenital Radiology has built the Prostate Imaging Reporting and Data System (PI-RADS) for standardizing the diagnosis of prostate cancer (PCa). This study evaluated the PI-RADS diagnosis method in patients with prostate-specific antigen (PSA) <20 ng/ml. Methods: A total of 133 patients with PSA <20 ng/ml were prospectively recruited. T2-weighted (T2WI) and diffusion-weighted (DWI) magnetic resonance images of the prostate were acquired before a 12-core transrectal prostate biopsy. Each patient's peripheral zone was divided into six regions on the images; each region corresponded to two of the 12 biopsy cores. T2WI, DWI, and T2WI + DWI scores were computed according to PI-RADS. The diagnostic accuracy of the PI-RADS score was evaluated using histopathology of prostate biopsies as the reference standard. Results: PCa was histologically diagnosed in 169 (21.2%) regions. Increased PI-RADS score correlated positively with increased cancer detection rate. The cancer detection rate for scores 1 to 5 was 2.8%, 15.0%, 34.6%, 52.6%, and 88.9%, respectively, using T2WI and 12.0%, 20.2%, 48.0%, 85.7%, and 93.3%, respectively, using DWL For T2WI + DWI, the cancer detection rate was 1.5% (score 2), 13.5% (scores 3-4), 41.3% (scores 5-6), 75.9% (scores 7-8), and 92.3% (scores 9-10). The area under the curve for cancer detection was 0.700 (T2WI), 0.735 (DWI) and 0.749 (T2WI + DWI). The sensitivity and specificity were 53.8% and 89.2%, respectively, when using scores 5-6 as the cutoff value for T2WI + DWI. Conclusions: The PI-RADS score correlates with the PCa detection rate in patients with PSA <20 ng/ml. The summed score of T2WI + DWI has the highest accuracy in detection of PCa. However, the sensitivity should be further improved.
Distinctive Precursory Air-Sea Signals between Regular and Super El Ninos

Statistically different precursory air-sea signals between a super and a regular El Nino group are investigated,using observed SST and rainfall data,and oceanic and atmospheric reanalysis data. The El Nino events during 1958-2008 are first separated into two groups: a super El Nino group (S-group) and a regular El Nino group (R-group). Composite analysis shows that a significantly larger SST anomaly (SSTA) tendency appears in S-group than in R-group during the onset phase [April-May(0)],when the positive SSTA is very small. A mixed-layer heat budget analysis indicates that the tendency difference arises primarily from the difference in zonal advective feedback and the associated zonal current anomaly (u'). This is attributed to the difference in the thermocline depth anomaly (D') over the off-equatorial western Pacific prior to the onset phase, as revealed by three ocean assimilation products. Such a difference in D' is caused by the difference in the wind stress curl anomaly in situ, which is mainly regulated by the anomalous SST and precipitation over the Maritime Continent and equatorial Pacific.
Pt/FeSnO(OH)_5: ANovel Supported Pt Catalyst for Catalytic Oxidation of Benzene

Pt/FeSnO(OH)_5 was synthesized as a novel catalyst for VOCs oxidation. Compared with Pt/γ-Al_2O_3 during catalytic oxidation of benzene, Pt/FeSnO(OH)_5 showed better catalytic activity. After characterization of the catalysts by XRD,SEM, TEM, EDS, XPS, BET, TGA and DTA, we found most Pt could be reduced to metallic state when the hydroxyl catalyst was used as supporter, and the metallic Pt in Pt/FeSnO(OH)_5 was more active than the oxidized Pt in Pt/γ-Al_2O_3 in catalytic oxidation of VOCs. Pt/FeSnO(OH)_5 shows both good catalytic activity and high stability, which may be a promising catalyst. This study may also be helpful for the design and fabrication of new catalysts.
Morphological changes and allometric growth in hatcheryreared Chinese loach Paramisgurnus dabryanus (Dabry de Thiersant, 1872)

The length-weight relationship and allometric growth patterns of hatchery-reared Chinese loach, Paramisgurnus dabryanus(Dabry de Thiersant, 1872),were determined from hatching to 60 days after hatching. A best power model was estimated for the length-weight relationship during the early life stages. Positive allometric growth for the head segment, trunk length, tail length and eye diameter was also found in the early life stages, while body depth, tail depth, tail fin length, pectoral fin length and barbel length displayed a negative coefficient. During the subsequent early developmental stage, the growth coefficients showed a clear and common tendency towards isometry for all measured body ratios. The allometric growth changes in Chinese loach during the early stage are possibly the result of selective organogenesis directed towards survival priorities.
Screening and isolation of the algicidal compounds from marine green alga Ulva intestinalis

Twenty species of seaweed were collected from the coast of Zhejiang, China, extracted with ethanol, and screened for algicidal activity against red tide microalgae Heterosigma akashiwo and Prorocentrum micans. Inhibitory effects of fresh and dried tissues of green alga Ulva intestinalis were assessed and the main algicidal compounds were isolated, purified, and identified. Five seaweed species, U. intestinalis, U.fasciata, Grateloupia romosissima, Chondria crassicaulis, and Gracilariopsis lemaneiformis, were investigated for their algicidal activities. Fresh tissues of 8.0 and 16.0 mg/mL of U. intestinalis dissolved in media significantly inhibited growth of H. akashiwo and P. micans, respectively. Dried tissue and ethyl acetate(EtOAc) extracts of U. intestinalis at greater than 1.2 and 0.04 mg/mL, respectively, were fatal to H. akashiwo, while its water and EtOAc extracts in excess of 0.96 and 0.32 mg/mL, respectively, were lethal to P. micans. Three algicidal compounds in the EtOAc extracts were identified as 15-ethoxy-(6z,9z, 12z)-hexadecatrienoic acid(I),(6E,9E, 12E)-(2-acetoxy -β-D-glucose)-octadecatrienoic acid ester(II) and hexadecanoic acid(III). Of these, compound II displayed the most potent algicidal activity with IC_(50) values of 4.9 and 14.1 μg/mL for H. akashiwo and P. micans, respectively. Compound I showed moderate algicidal activity with IC_(50) values of 13.4 and 24.7 μg/mL for H. akashiwo and P. micans, respectively. These findings suggested that certain macroalgae or products therefrom could be used as effective biological control agents against red tide algae.
The metabolite profiling of coastal coccolithophorid species Pleurochrysis carterae (Haptophyta)

Pleurochrysis carterae is a calcified coccolithophorid species that usually blooms in the coastal area and causes aquaculture losses. The cellular calcification, blooming and many other critical species specific eco-physiological processes are closely related to various metabolic pathways. The purpose of this study is to apply the unbiased and non-destructive method of nuclear magnetic resonance(NMR) to detect the unknown holistic metabolite of P. carterae. The results show that NMR spectroscopic method is practical in the analysis of metabolites of phytoplankton. The metabolome of P. carterae was dominated by 26 metabolites involved in a number of different primary and secondary metabolic pathways. Organic acids and their derivatives, amino acids, sugars, nucleic aides were mainly detected. The abundant metabolites are that closely related to the process of cellular osmotic adjustment, which possibly reflect the active ability of P. carterae to adapt to the versatile coastal niche. DMSP(dimethylsulphoniopropionate) was the most dominant metabolite in P. carterae, up to 2.065±0.278 mg/g lyophilized cells, followed by glutamate and lactose, the contents were 0.349±0.035 and 0.301±0.073 mg/g lyophilized cells respectively. Other metabolites that had the content ranged between 0.1-0.2 mg/g lyophilized cells were alanine, isethionate and arabinose. Amino acid(valine, phenylalanine, isoleucine, tyrosine), organic acid salts(lactate, succinate), scyllitol and uracil had content ranged from 0.01 to below 0.1 mg/g lyophilized cells. Trigonelline, fumarate and formate were detected in very low content(only thousandths of 1 mg per gram of lyophilized cells or below). Our results of the holistic metabolites of P. carterae are the basic references for the further studies when multiple problems will be addressed to this notorious blooming calcifying species.
我国心力衰竭心脏再同步化治疗的现状与对策

慢性心力衰竭(心衰)是各类心脏疾病的严重阶段或终末期表现,尽管指南推荐“金三角”药物治疗可改善患者预后,但5年病死率仍然很高[1]。因此,在药物治疗基础上选择合适的患者进行器械治疗是目前临床关注的热点。心脏再同步化治疗(cardiac resynchronization therapy,CRT)和埋藏式除颤器(implantable cardioverter-defibrillator, ICD)可改善心衰患者生活质量,降低病死率,减少心脏性猝死的发生,已成为目前慢性心衰的主要治疗方法之一。近年来一系列临床研究,进一步推动了CRT国际和国内指南的更新,巩固了其作为心衰临床一线治疗的地位。然而,相比于欧美国家,CRT在国内的临床应用相对滞后,每百万人口植入率仍远低于西方国家。原因并非技术落后,而主要在于国内心血管医生对于心衰患者CRT获益认知不足,导致对CRT适应证理解不够深入。其次,经济条件的限制也是阻碍其发展的重要因素,相比于其他心脏介入治疗方式,患者自行承担的费用比例较高。因此,结合我国国情,以指南所推荐的适应证为基础,深入探究可能从CRT中获益更多的心衰患者,达到临床获益和卫生经济学效益的双重最大化,是目前临床工作的重点。
手部热压伤的治疗及疗效分析

热压伤指热烧伤同时伴有挤压撕裂等损伤,由于致伤原因较复杂,而且致伤物往往温度高、压力大,因此除烧伤外,往往还合并肌肉、肌腱、骨骼的损伤,常遗留畸形致手功能部分或完全丧失.甚至失去生活自理能力。早期封闭创面和功能锻炼对日后功能恢复至关重要。我科自2007年7月至2011年7月对25例热压伤患者采取急诊修复创面及肌腱,术后及时进行功能康复锻炼,效果满意。