mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Impact of potentially lethal ventricular arrhythmias on long-term outcome in patients with chronic heart failure

Background Potentially lethal ventricular arrhythmias (PLVAs) occur frequently in survivors after acute myocardial infarction and are increasingly recognized in other forms of structural heart diseases. This study investigated the prevalence and prognostic significance of PLVAs in patients with chronic heart failure (CHF). Methods Data concerning demographics, etiology of heart failure, NYHA functional class, biochemical variables, electrocardiographic and echocardiographic findings, and medical treatments were collected by reviewing hospital medical records from 1080 patients with NYHA II–IV and a left ventricular (LV) ejection fraction ≤45%. PLVAs were defined as multi-focal ventricular ectopy (>30 beats/h on Holter monitoring), bursts of ventricular premature beats, and nonsustained ventricular tachycardia. All-cause mortality, sudden death, and rehospitalization due to worsening heart failure, or cardiac transplantation during 5-year follow-up after discharge were recorded. Results The occurrence rate of PLVAs in CHF was 30.2%, and increased with age; 23.4% in patients <45 years old, 27.8% in those between 45–65 years old, and 33.5% in patients >65 years old (P=0.033). Patients with PLVAs had larger LV size and lower ejection fraction (both P <0.01) and higher all-cause mortality (P=0.014) during 5-year follow-up than those without PLVAs. Age (OR 1.041, 95% CI 1.004–1.079, P=0.03) and LV end-diastolic dimension (OR 1.068, 95% CI 1.013–1.126, P=0.015) independently predicted the occurrence of PLVAs. And PLVA was an independent factor for all-cause mortality (RR 1.702, 95% CI 1.017–2.848, P=0.031) and sudden death (RR 1.937, 95% CI 1.068–3.516, P=0.030) in patients with CHF. Conclusion PLVAs are common and exert a negative impact on long-term clinical outcome in patients with CHF.
食管克罗恩病

克罗恩病从口腔至肛门各段消化道均可受累,但病变多见于末端回肠及邻近结肠,表现为食管克罗恩病的少见。食管克罗恩病临床上主要表现为胸骨后疼痛或吞咽困难,易误诊为食管癌。多次胃镜检查、活检获得其特征性病理组织学论据可提高确诊率,多数需经手术后病理检査确诊。本例术前误诊为食管癌,可能因:①食管克罗恩病少见;②胃镜肉眼所见无纵裂隙样溃疡、管腔狭窄和卵石样黏膜改变等克罗恩病的典型特征;③表现为食管中段增生性病变基础上出现深溃疡,继之出现结节样改变,且病变短期内发生较大变化酷似食管癌。术后病理组织学检查发现溃疡形成,管壁水肿增厚,纤维组织增生及非干酪样肉芽肿形成排除结核而确诊为食管克罗恩病。本例克罗恩病不伴有回肠末端原发病灶实属罕见。食管克罗恩病目前尚无特异有效的治疗方法,外科手术治疗仅适用于病变局限、药物治疗无效、已有食管梗阻、合并穿孔、内瘘、出血者。食管克罗恩病有反复发作的倾向,术后并发症、复发率均较高。文献报道食管克罗恩病经甲硝唑与柳氮磺胺吡啶或糖皮质激素等药物治疗可以使病情缓解,甚至治愈。提高对该病的认识可减少不必要的手术,对食管孤立性病变短期内出现溃疡形成及修复表现者,应考虑到食管克罗恩病的可能。
Ph阳性急性淋巴细胞白血病的治疗进展与思考

酪氨酸激酶抑制剂(TKI)纳入Ph阳性急性淋巴细胞白血病(Ph~+ALL)的治疗显著改善了其疗效,近95%的患者达到完全缓解(CR),经定量检测70%的患者骨髓bcr-abl转录本转为阴性,3年生存率可达55%。这种新的治疗方式,不仅为CR期患者提供了接受异基因造血干细胞移植(allo-HSCT)的机会,也有助于延长不能移植患者的缓解期。但是,什么是最佳的诱导治疗方案?allo-HSCT联合TKI的作用和具体策略是什么?什么是最有效的维持治疗方案?如何克服伊马替尼耐药?新型TKI在Ph~+ALL治疗中具有何种地位?以上诸多问题,仍然存在争论和思考。
穿心莲化学成分的研究

目的研究穿心莲Andrographis paniculata的化学成分。方法利用硅胶柱色谱、聚酰胺柱色谱、Sephadex LH-20凝胶柱色谱、ODS柱色谱、反相制备色谱等技术进行分离,并根据理化性质和波谱学手段对分得的化合物进行结构鉴定。结果分离得到10个化合物,分别鉴定为穿心莲酸(1)、芹菜素-7-O-β-D-葡萄糖醛酸丁酯(2)、芹菜素-7-O-β-D-葡萄糖醛酸乙酯(3)、木犀草素-7-O-β-D-葡萄糖醛酸苷(4)、金合欢素-7-O-β-D-葡萄糖醛酸苷(5)、芹菜素-7-O-β-D-葡萄糖醛酸苷(6)、异高黄芩素-8-O-β-D-葡萄糖醛酸苷(7)、芹菜素-7-O-β-D-葡萄糖苷(8)、6-C-β-D-葡萄糖-8-C-β-D-半乳糖芹菜素(9)、绿原酸(10)。结论化合物2~7、9、10为首次从穿心莲属植物中分离得到。
线叶菊抗感染有效部位化学成分的研究(Ⅰ)

目的对线叶菊Filifolium sibiricum抗感染有效部位进行化学成分研究。方法采用大孔吸附树脂柱色谱、硅胶柱色谱、ODS柱色谱及高效液相色谱等多种色谱分离技术,制备单体化合物,根据物理常数及波谱数据对化合物进行结构鉴定。结果共分离得到12个黄酮类化合物,分别鉴定为异荭草素(1)、异牡荆苷(2)、芹菜素-6-阿拉伯糖基-8-葡萄糖苷(3)、芹菜素-3′-甲氧基-7-O-芸香糖苷(4)、槲皮素(5)、金丝桃苷(6)、异槲皮苷(7)、异鼠李素-3-O-葡萄糖苷(8)、异鼠李素-3-O-芸香糖苷(9)、槲皮素-3-O-芸香糖基-7-O-葡萄糖苷(10)、圣草次苷(11)和圣草素(12)。结论化合物1~11为首次从线叶菊属植物及线叶菊中分离得到,黄酮类化合物为线叶菊抗感染有效部位的重要组成成分。
早熟丰产水稻新品种龙粳28

水稻新品种龙粳28(原代号为龙育04-1465)是黑龙江省农业科学院水稻研究所通过常规系统选育而成。该品种属于早熟、优质、丰产、多抗、适应性强的大粒型水稻新品种。2009年1月经黑龙江省农作物品种审定委员会审定推广，审定编号为“黑审稻2009011”。
Electrodeposition and Characterization of Polyaniline Film

Polyaniline film was prepared by electrochemical method in an acidic solution of aniline. The micromor phology of the polyaniline film was transformed to three-dimensional network structure instead of little particles while the deposition time was extended. The peak wavelength of the photoluminescence spectrum was 491 nm. The luminous intensity increased with the extension of deposition time, and so did the electrochemical activity.
O_xidative dehydrogenation of propane over Ni-Mo-Mg-O catalysts

In this work, a series of Ni-Mo-Mg-O catalysts with mesoporous structure prepared by sol-gel method were investigated for the oxidative dehydrogenation of propane (ODHP). The techniques of temperature-programmed reduction with H_2 (H_2-TPR), N_2 adsorption-desorption, Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and X-ray photoelectron spectra (XPS) were employed for catalyst characterization. It is found that the activity of the catalysts for ODHP increases first and then decreases with the increase of Mo content. The catalyst with a Mo/Ni atomic ratio of 1/1 exhibits the best catalytic activity, which gives the propene selectivity of 81.4% at a propane conversion of 11.3% under 600°C and maintains the good catalytic performance for 22 h on stream. This is related not only to its high reducibility and dispersion as revealed by TPR and XRD, but also to the formation of more selective oxygen species on the MoO_x-NiO interface as identified by XPS.
Removal of high concentration CO_2 from natural gas at elevated pressure via absorption process in packed column

Carbon dioxide (CO_2) removal is an essential step in natural gas (NG) processing to provide high quality gas stream products and minimize operational difficulties. This preliminary study aims to investigate the removal of CO_2 at high concentration level from the mixture of CO_2-NG gas stream at elevated pressure via absorption process. This is to explore the possibility of exploring high CO_2 content natural gas reserves by treatment at offshore platform. A mixed amine solvent, Stonvent-II, was used for the absorption of approximately 75 vol% CO_2 in CO_2-NG stream at a pressure of 10 barg. The initial solvent temperature was varied in order to study the impact of initial temperature on the absorption performance. Preliminary study at temperatures of 35°C and 45°C indicates that Stonvent-II was able to perform almost 100% removal of CO_2 under both conditions. However, the CO_2 absorption effect took place faster when the initial liquid temperature was lower. This is because when the initial liquid temperature is high, the temperature increase in the packing bed caused by the reaction heat is high which impacts the efficiency of absorption negatively.
原辅料及不同压片工艺对藿精片质量的影响

目的考察制粒法和直压法压片生产过程中原辅料及工艺对藿精片质量的影响。方法对选用的原辅料流动性、吸湿性相关的特性指标进行测定,分别采用制粒法和直压法工艺制备藿精片,测定两种工艺用于压片的颗粒或混粉的流动性、吸湿性指标,建立测定淫羊藿苷高效液相色谱法,测定原料及两种工艺制备的成品片中淫羊藿苷,并按照中国药典2010年版规定方法测定片剂的脆碎度、崩解时限、水分、片质量差异及外观等指标。结果选择的辅料可以改善原料的吸湿性,压缩度及直压法混粉的流动性,制粒法的颗粒流动性优于混粉,均可避免原料造成的黏冲现象。结论制粒法和直压法压片工艺对藿精片中淫羊藿苷含有量略有影响,而对其它质量指标没有什么影响。
汤剂煎煮的规范化研究方法探讨

汤剂作为中医治病应用最多最主要的剂型,其煎煮方法自古以来就备受关注,本文针对汤剂煎煮的规范化研究,从其意义、现状和存在问题,标准汤剂的建立方法等方面进行探讨,并展望其未来发展。
闭合复位逆行交锁髓内钉治疗股骨远端骨折

[目的]探讨股骨逆行交锁髓内钉治疗效果。[方法]2004年3月~2010年2月,47例股骨远端骨折患者采用C型臂X线机下闭合复位逆行交锁髓内钉治疗并早期行膝关节功能锻炼。[结果]47例患者均获得随访,随访时间9~18个月,平均10个月,全部骨性愈合,膝关节功能良好。骨折平均愈合时间15周,据HSS膝关节临床功能评分标准:优22例、良19例、一般6例。优良率87.2%。[结论]闭合复位逆行交锁髓内钉能提供坚强内固定,出血少,创伤小,有利于骨折愈合和膝关节功能的恢复,是治疗股骨远端骨折的较好方法。
膝骨性关节炎与膝内翻畸形发生发展的关系及治疗

膝关节骨性关节炎(KOA)是一个以关节软骨退行性改变和丢失为核心,继发关节边缘和软骨下骨质增生为特征的慢性关节炎症性疾病。近年来,随着骨性关节炎所导致的疼痛、关节炎的病因学和发病机制的研究逐渐深入。有关膝内翻畸形的因素不仅仅是作为膝OA 形成和发展的病因之一，而且膝OA 也会进一步导致膝内翻畸形的改变，故以下将重点探讨膝内翻畸形发生因素和X 线片改变及胫骨高位截骨矫正术的研究概况。
Astrophysical parameters of ten poorly studied open star clusters

We present the fundamental parameters of ten open star clusters,nominated from Kronberger et al.who presented some newly discovered stellar groups on the basis of the Two Micron All Sky Survey photometry and Digitized Sky Survey visual images.Star counts and photometric parameters(radius,membership,distance,color excess,age,luminosity function,mass function,total mass,and dynamical relaxation time) have been determined for these ten clusters for the first time.In order to calibrate our procedures,the main parameters(distance,age,and color excess) have been reestimated for another five clusters,which are also studied by Kronberger et al.
Targeting and utilizing primary tumors as live vaccines: changing strategies

Tumor metastases and relapse are the major causes of morbidity and mortality in cancer. Although surgery, chemotherapy and/or radiation therapy can typically control primary tumor growth, metastatic and relapsing tumors are often inaccessible or resistant to these treatments. An adaptive immune response can be generated during these conventional treatments of the primary tumor, and presumably both the primary tumor and secondary metastases share many of the same or similar antigenic characteristics recognized by the immune system. Thus, when established, this response should be able to control metastatic growth and tumor relapse. This review summarizes the mechanisms by which antitumor immune responses are generated, and recent findings supporting the hypothesis that many therapies targeting primary tumors can generate antitumor adaptive immune responses to prevent metastases and tumor relapse.
胃左动脉灌注化疗/栓塞治疗47例晚期贲门癌的临床分析

目的观察选择性插管经胃左动脉灌注化疗药物/栓塞治疗晚期贲门癌的疗效。方法对47例晚期贲门癌患者行胃左动脉插管灌注化疗药物并栓塞，观察近期疗效和不良反应。结果完全缓解(CR)10例(21.28%)，部分缓解(PR)27例(57.45%)，总有效率(CR+PR)为78.72%。中位生存期9.6个月,1年生存率为23.40%(11/47)。主要不良反应为骨髓抑制和胃肠道反应。结论经胃左动脉灌注化疗/栓塞治疗晚期贲门癌近期疗效明显,安全,可靠,不良反应轻,耐受性良好。
射频热凝术对18例变应性鼻炎患者鼻黏膜中VIP与NPY的影响

目的研究双侧翼管、筛前神经丛集区射频热凝术对变应性鼻炎(AR)患者鼻黏膜中血管活性肠肽(VIP)与神经肽Y(NPY)的影响。方法 2009年11月至2010年9月在桂林医学院附属医院随机选取18例AR患者接受双侧翼管、筛前神经丛集区射频热凝术。分别在术前和术后2个月采用免疫组织化学检测鼻黏膜VIP、NPY水平，以15例鼻中隔偏曲患者为对照组。结果免疫组织化学显示术后鼻黏膜中VIP阳性细胞数较术前显著下降，而NPY阳性细胞数则显著增加(P<0.05)，与对照组比较差异无统计学意义(P>0.05)。结论双侧翼管、筛前神经丛集区射频热凝术能改变鼻黏膜中VIP和NPY含量，从而达到有效治疗AR的目的。
磷酸钙骨水泥强化在颈椎前路带锁钢板螺钉固定的临床价值

目的探讨磷酸钙骨水泥(CPC)加强颈椎前路带锁钢板螺钉固定的临床应用疗效。方法回顾性分析2005年2月至2009年6月采用颈椎前路带锁钢板螺钉治疗的68例颈椎病患者临床资料,其中CPC加固组(CPC组)37例,男23例,女14例;年龄22~63岁,平均52.9岁。单纯内固定组(非CPC组)31例,男19例,女12例;年龄25~62岁,平均54.3岁。两组中神经根型10例,脊髓型45例,混合型13例。31例伴有严重骨质疏松。结果68例患者术后均获10~32个月(平均23个月)随访。术后切口均获一期愈合。CPC组和非CPC组的手术时间平均分别为(151.4 ± 20.2)、(141.1 ± 19.7)min,术中出血量平均分别为(268.5 ± 0.1)、(262.7 ± 75.3) mL,比较差异均无统计学意义(P > 0.05).X线片示患者植骨均获融合,融合时间为8~16周,平均12周。两组患者植骨融合率、术后神经功能改善率比较差异均无统计学意义(P > 0.05),内置物相关并发症发生率比较差异有统计学意义(P<0.05)。结论CPC加固颈椎前路钢板螺钉治疗颈椎病可获得满意疗效,且可以减少术后内置物相关并发症的发生。
A novel tumor suppressor miRNA miR-520e contributes to suppression of hepatoma

Hepatocellular carcinoma (HCC), one of the most common cancers worldwide, represents the third cause of cancer-related death[1]. Curative options for HCC are limited and exclusively available for patients carrying an early stage HCC. In advanced stages, traditional chemotherapy proved to be only marginally effective or even toxic. Thus, the identification of new treatment options is needed. New targets for nonconventional treatment will necessarily take advantage of progresses on the molecular pathogenesis of HCC[2].
肝移植术后免疫抑制剂的联合应用

器官移植作为20世纪最伟大的技术革命之一,免疫抑制剂的问世和发展起到了巨大的推动作用,尽管距离免疫抑制的最终目标即免疫耐受仍然相距甚远,但我们目前确实已经进入后免疫抑制时代。在拥有更多选择的同时,免疫抑制剂的各种不良反应也随着时间累积效应逐渐显现,如何互补性的联合应用免疫抑制剂,使免疫抑制方案的有效性和安全性达到最优化,成为目前器官移植领域的热点问题。现结合我中心经验,对肝移植术后免疫抑制剂的联合应用进行介绍。
第73例—右侧肢体无力45天,伴梅毒感染史

典型的梅毒临床和病理表现已经被大家所熟知。但随着HIV感染的逐渐增多，HIV合并梅毒的病例也越来越多,其临床谱和病理改变均不典型,且进展快，病情重，给临床诊治带来很大的困难。通过本例的讨论，我们对梅毒这种古老疾病的认识又加深了一步;遗憾的是本例未能行全身尸检，其具体死因不得而知，但中枢病变应不是致死原因。
输注喹诺酮类药物的护理

喹诺酮类药物因抗菌效果确切,抗菌谱广,经常输注喹诺酮类药物用于治疗感染。但此类药物对血管、胃肠道刺激较强,给患者造成一定的痛苦。在临床实践中也逐步发现了一些严重的不良反应。
彩色多普勒超声诊断头静脉瘤合并血栓及静脉石形成1例

患者男,54岁,因"发现右前臂肿块1年余伴压痛"就诊。外科检查:右前臂桡侧扪及约2cm结节,边界清晰,质软,有压痛。超声:右前臂桡侧中段头静脉局部瘤样扩张,呈梭形,最大内径约8mm(其远、近端内径均约2mm),长度约15mm,内部可见絮状低回声,探头加压管腔部分消失;另见约3mm强回声斑,后伴声影,探头推之可移动(图1)。CDFI:上述瘤样扩张的管腔内见静脉血流信号,并见充盈缺损(图2)。超声提示:右头静脉瘤合并血栓及静脉石形成。药物治疗2个月后复查,瘤体及内血栓无明显变化,患者要求手术治疗。术后病理诊断:(右)头静脉瘤,伴血栓及静脉石形成。
正畸治疗中颞下颌关节问题的应对策略

颞下颌关节紊乱病(temporomandibular disorders,TMD)是一组涉及咀嚼肌、颞下颌关节(temporomandibular joint,TMJ)及其相关结构的临床疾病的统称。临床中常表现为关节区疼痛、弹响或下颌运动障碍,特别是关节弹响在儿童和青少年中很普遍,而在15-25岁有增多的趋势。由于人们对美观的需求日益提高,同时随着隐形矫治器(舌侧矫治器或无托槽矫治器)的发展,成年正畸患者的数量不断增加。此外,由于正畸治疗通常持续2年左右,增加了患者出现TMD的可能性,因此部分患者认为其关节问题是由正畸治疗所致,并由此产生一些医疗纠纷和诉讼。正畸医师开始逐渐重视(牙合)因素、正畸治疗与TMD的关系等问题,相关的研究也越来越多。
肌内效贴短期缓解膝关节骨性关节炎症状的疗效研究

目的：初步探讨肌内效贴短期缓解膝关节骨性关节炎症状的临床疗效。方法：膝关节骨性关节炎患者共40例，按年龄、性别及体重及急慢性期等严格配对后随机分为肌内效贴组+常规局部理疗组(治疗组)及常规局部理疗组(对照组)各20例。在入选时、治疗3d及7d时对两组患者的疼痛度(视觉模拟评分，VAS)、肿胀评分(Lequesne肿胀评分)及综合功能(西安大略及麦克马斯特大学骨关节炎指数评分，WOMAC)作评估，同时对过敏性与安全性进行评价。结果：两组在治疗前基线值及病情比较差异无显著性意义，在第3天患者疼痛度及肿胀度评分治疗组患者比对照组有显著差异(P<0.05，t=7.2163，t=4.8472)，疗程第7天，两组疼痛及肿胀度评分比较趋向一致(P>0.05，t=2.5218，t=0.7840)，均较治疗前有显著差异。WOMAC评分治疗组与对照组相比在疗程第3天、第7天仍有显著性差异(Fwomac=12.6，P<0.05)。治疗组有1例疑似轻度过敏，但未影响疗程的完整进行。结论：肌内效贴可作为安全有效的康复手段之一，短期缓解膝关节骨性关节炎患者症状，改善综合功能，其相应机制及更优化的贴扎方式有待后续研究。
宁波地区新生儿首剂乙型肝炎疫苗接种分析

乙型肝炎是严重危害人类健康的疾病之一，目前接种乙肝疫苗(HepB)是预防和控制乙肝病毒(hepatitis B virus,HBV)感染最有效的公共卫生干预措施。浙江省宁波市自1989年起在城区实施新生儿乙肝疫苗普种,1991年扩展至余姚、宁海等市、县,自1992年宁波市全面将HepB纳入儿童计划免疫。现将余姚、宁海(市)县医院出生的新生儿首针HepB接种情况分析如下。
Characterizations and mechanical properties of impregnated diamond segment using Cu-Fe-Co metal matrix

Diamond impregnated Cu-Fe-Co based saw-blade segments are directly processed by vacuum and pressure-assisted sintering at different temperature,with the purpose of reducing the cobalt content in diamond tools.Copper and iron are used as the bonding elements and co-balt-chrome pre-alloyed powder is used as the hardening phase.Effects of sintering temperature on microstructures and mechanical properties of the sintered matrix and diamond graphitization were investigated by X-ray diffraction analysis,electron probe micro-analyzer,universal testing machine,digital Rockwell hardness tester and Raman scattering analyzer.Results showed that microstructures of the sintered matrix were refined and porosities in the sintered matrix were closed to a more spherical-like shape with the increase of the sintering temperature.Densification,hardness and tensile strength of the matrix sintered at 820 ℃ were 12.75%,2.72% and 156.38% higher than that of the matrix sintered at 740 ℃,respectively.Diamond graphitization was not occurred at 820 ℃.The hardness and the tensile strength rose 32.8% and 13.5%,respectively,after 7.5 h ageing treatment.The matrix densification ascent and the dispersed distribution of Co-Cr pre-alloyed powders contributed a hardness improvement and a tensile strength improvement to the Cu-Fe based matrix.
Effects of nano-TiO2 dispersion on thermoelectric properties of Co4Sb11.7Te0.3 composites

Nano-TiO2/Co4Sb11.7Te0.3 composites were prepared by mechanical alloying (MA) and cold isostatic pressing (CIP) process.The phase composition,microstructure,and thermoelectric properties were characterized.The diffraction spectra of all samples well corresponds to CoSb3 skutterudite diffraction plane.TiO2 agglomerates into irregular clusters.They locate at the grain boundaries or some are distributed on the surface of Co4Sb11.7Te0.3 particles.For composites with high TiO2 content (0.6% and 1.0% TiO2),the phonon scattering by TiO2 particle,pores,and small size grains can result in a remarkable reduction in thermal conductivity.The maximum value of ZT is 0.79 for sample with 0.6 wt.% TiO2 at 700 K,which is 11% higher than that of non-dispersed sample.
New Explorations on Cannon's Contributions and Generalized Solutions for Uniform Linear Motion Blur Identification

Existing frequency-domain-oriented methods of parameter identification for uniform linear motion blur (ULMB) images usually dealt with special scenarios. For example, blur-kernel directions were horizontal or vertical, or degraded images were of foursquare dimension. This excludes those identification methods from being applied to real images, especially to estimate undersized or oversized blur kernels. Pointing against the limitations of blur-kernel identifications, discrete Fourier transform (DFT)-based blur-kernel estimation methods are proposed in this paper. We analyze in depth the Fourier frequency response of generalized ULMB kernels, demonstrate in detail its related phase form and properties thereof, and put forward the concept of quasi-cepstrum. On this basis, methods of estimating ULMB-kernel parameters using amplitude spectrum and quasi-cepstrum are presented, respectively. The quasi-cepstrum-oriented approach increases the identifiable blur-kernel length, up to a maximum of half the diagonal length of the image. Meanwhile, directing toward the image of undersized ULMB, an improved method based on quasi-cepstrum is presented, which ameliorates the identification quality of undersized ULMB kernels. The quasi-cepstrum-oriented approach popularizes and applies the simulation-experimentfocused DFT theory to the estimation of real ULMB images. Compared against the amplitude-spectrum-oriented method, the quasi-cepstrum-oriented approach is more convenient and robust, with lower identification errors and of better noiseimmunity.
单侧银屑病误诊一例

体检:一般情况尚可,心肺腹部体检未见明显异常,四肢关节无畸形,活动正常。皮肤科检查:右侧腹背部至右股部见鳞屑性红斑,皮疹局限呈片状分布,可见点状出血现象(图1),头皮,掌跖等其他部位未见皮疹。实验室检查:血尿粪常规、红细胞沉降率、生化检查无异常,血RPR、TPPA、HIV及支原体衣原体检查无异常,血自身免疫抗体检查无异常;胸部及四肢关节X线摄片检查均无异常。取右侧腰部皮疹组织病理检查示:角化不全,表皮增生肥厚,皮突延长;真皮乳头毛细血管扩张迂曲,乳头上方表皮变薄,真皮浅层血管周围淋巴组织细胞浸润(图2)。结合临床,诊断:寻常性银屑病。治疗:局部外用复方曲安萘德樟脑乳膏(本院制剂),维A酸乳膏,口服中草药方凉血消风汤(本院制剂)20d后皮疹消退,3个月内皮疹未复发,目前仍在随访中。
CTLA-4基因多态性与哮喘遗传易感性研究进展

哮喘是一种受环境因素影响的多基因遗传病，基因-免疫-环境之间的交互作用在哮喘的形成和发展中至关重要。多基因遗传病是由多个基因突变引起的，任何一个基因的突变对于疾病的发生既非必要条件，亦非充分条件，几个基因突变的效应可以累积，其发病风险和病情的严重程度存在数量累积趋势。此外，遗传易感因素虽决定个体的发病风险，但环境因素可能是疾病的触发因素。上述CTLA-4基因多态性与哮喘易感性研究结果不尽一致，可能缘于研究对象样本量小、人群间遗传差异和（或）不同的基因-环境交互作用~([18])。虽然CTLA-4基因多态性与哮喘相关的证据不多或强度不够，但现有资料多支持其与特应性（过敏性）有关，而哮喘则是一种常见的过敏症。关于中国人群CTLA-4基因多态性与哮喘易感性的研究甚少，深入研究我国人群CTLA-4等位基因多态性与哮喘表型之间的关系，综合探讨基因-细胞免疫-环境之间的交互作用，将有助于发现与哮喘易感性相关的危险基因型，并有望作为分子标志物用于筛选哮喘的高危人群或易感个体。全基因组关联研究在全基因组水平上筛选与哮喘关联的SNP，有助于了解CTLA-4基因多态性与其他SNP和环境之间的交互作用，为今后研究哮喘的分子遗传学发病机制提供了新的思路和策略。
运动疗法结合推拿治疗对肩周炎患者肩关节功能的影响

肩周炎是肩周肌、肌腱、滑囊以及关节囊的慢性损伤性炎症，因关节内外粘连，而导致活动时疼痛和肩关节功能活动障碍，康复治疗的目的在于减轻患者疼痛，恢复肩关节活动功能。本研究采用运动疗法结合推拿治疗肩周炎，疗效明显，现报道如下。
左颈部神经鞘瘤伴双异位甲状腺一例

神经鞘瘤伴发异位甲状腺的病例尚无报道,曾有异位甲状腺误诊为颈部神经鞘瘤的报道~([6]);甲状腺区可以发生神经鞘瘤,是由于甲状腺区的神经鞘瘤主要来自喉上、喉返、三叉及颈丛神经等~([7-9])。本例患儿术前术后均未出现明显饮水呛咳及声音嘶哑,故可排除其喉上、喉返神经来源的可能。因此,对于颈部包块应常规检查甲状腺及甲状旁腺功能,了解其大小、位置、性质及关系,避免误诊、误切或盲目取活检,而造成严重并发症。而神经鞘瘤与异位甲状腺的发生是否有关,尚需临床诊疗中进一步归纳分析。
Effect of niobium promoter on iron-based catalyst for Fischer-Tropsch reaction

Niobium-promoted Fe/CNTs catalysts were prepared using a wet impregnation method.Samples were characterized by nitrogen adsorption,H_2-TPR,TPD,XRD and TEM.The Fischer-Tropsch Synthesis(FTS) was carried out in a fixed-bed microreactor at 220 ℃,1 atm and H_2/CO=2 for 5 h.Addition of niobium into Fe/CNTs increased the dispersion,decreased the average size of iron oxide nanoparticles and the catalyst reducibility.Niobium-promoted Fe catalyst resulted in appreciable increase in the selectivity of C_(5+) hydrocarbons and suppressed methane formation.These effects were more pronounced for the 0.04%Nb/Fe/CNTs catalyst,compared to those observed from other niobium compositions.The 0.04%Nb/Fe/CNTs catalyst enhanced the C_(5+) hydrocarbons selectivity by a factor of 67.5% and reduced the methane selectivity by a factor of 59.2%.
Dispersion modeling and health risk assessment of dioxin emissions from a municipal solid waste incinerator in Hangzhou,China

The emission of dioxins from municipal solid waste incinerators(MSWIs) has become a widespread concern.The effect of meteorological parameters(wind speed,atmospheric stability and mixing height) on the hourly ground level concentration(GLC) of dioxins was estimated using air dispersion models.Moreover,the health risks of dioxin exposure were evaluated for children and adults using the Nouwen equation.The total environmental exposure via air inhalation and food ingestion was calculated,based on linear fit equations.The results indicate that potentially severe pollution from dioxins occurs at a wind speed of 1.5 m/s with atmospheric stability class F.In addition,local residents in the study area are exposed to severe weather conditions most of the time,and the risk exposures for children are far higher than those for adults.The total exposure for children far exceeds the tolerable daily intake of dioxin recommended by the World Health Organization(WHO) of 1-4 pg TEQ/(kg·d) under severe weather conditions.Results from modeling calculations of health risk assessment were consistent with dioxin levels obtained during actual monitoring of emissions.
Steady-state response of a saturated half-space with an overlying dry layer subjected to a moving load

In this paper,the steady-state response of a saturated half-space with an overlying dry layer subjected to a moving rectangular load is investigated.The governing partial differential equations are solved using the Fourier transform.The solutions in time-space domain are expressed in terms of infinite Fourier type integrals,which can be evaluated only by numerical quadrature.Numerical results show that the influence of a drained or undrained interface on the response is related to the permeability of the underlying saturated soil.Moreover,the effect due to the upper dry layer is associated with the thickness of the layer.
手助腹腔镜结直肠癌根治术42例报告

随着腹腔镜技术的发展，尤其是蓝碟的发明问世，手助腹腔镜技术(hand assisted laparoscopic surgery,HALS)在普通外科疾病诊治中发挥越来越大的作用。我科2010年10月至2011年4月期间对42例结直肠癌患者采用手助式腹腔镜实施结直肠癌根治术，近期疗效满意，现报道如下。
在医学教育中继续加强微生态学教学改革的思考

微生态学是研究正常微生物群与其宿主相互关系的生命科学分支，是细胞水平或分子水平的生态学~([1])。微生态学是一门理论与实践密切相结合的新兴学科。微生态学理论来源于实践，又回归于实践，并指导实践。在欧美国家、日本，微生态学技术及微生态制剂得到了广泛应用。在医学方面，近年来国内用于治疗预防、保健的微生态制剂也有了迅猛的发展。
Sensor design and implementation for a downhole NMR fluid analysis laboratory

This paper tries to build a multi-functional downhole nuclear magnetic resonance (NMR) fluid analysis laboratory that can evaluate fluid information in real time at reservoir conditions at a depth of several thousand meters. The aim is to monitor the pollution of the formation fluids and quantitatively evaluate NMR characteristics of the fluids. It focuses on the design of the structure and parameters of a sensor with zero stray fields. Two separate coils are designed to measure NMR characteristics of flowing or static fluids. A method is proposed to use the Bloch equation, to guide the optimization of the NMR sensor. Finally, the measured results confirm that the design is reasonable. There is a homogeneous static field (perpendicular to the axial direction) in the center of the sensor, and there are no stray external fields. The novel design of pre-polarization magnet improves the signal to noise ratio, while shortening the sensor length.
Power optimization of gas pipelines via an improved particle swarm optimization algorithm

In past decades dynamic programming, genetic algorithms, ant colony optimization algorithms and some gradient algorithms have been applied to power optimization of gas pipelines. In this paper a power optimization model for gas pipelines is developed and an improved particle swarm optimization algorithm is applied. Based on the testing of the parameters involved in the algorithm which need to be defined artificially, the values of these parameters have been recommended which can make the algorithm reach efficiently the approximate optimum solution with required accuracy. Some examples have shown that the relative error of the particle swarm optimization over ant colony optimization and dynamic programming is less than 1% and the computation time is much less than that of ant colony optimization and dynamic programming.
急性胰腺炎:主流观念的变迁与困惑

<正>重症急性胰腺炎(acute severe pancreatitis,SAP)当前仍然是一个病死率高、并发症严重、临床治疗棘手、恢复需时较长的疾病;外科治疗经过半个多世纪的徘徊,对手术的位置与作用的认识已有深刻的改变,外科的微创化与个体化已成共识,微创外科的前提建立在挽救性命、保护功能、促进愈合的损伤控制(damage control)的理念上,但是从当前趋势看来，却又不能从一个极端走到另一个极端，否定外科的作用。胰腺被喻为腹腔内的“隐士”，但“隐士”有时也猖狂。回顾过去几十年在SAP的治疗上走过的风雨历程，我们要避免极端，从保守的极端走向手术的极端，又从手术的极端回到保守的极端，这不是科学发展的道路，需要找寻新的出路。
利胆排石汤加减治疗胆石症疗效观察

<正>由于人们生活节奏加快、饮食结构失衡等因素,胆石症的发病率逐年上升。笔者临床运用自拟利胆排石汤加减治疗胆石症取得较好的疗效,现报道如下。
NMR identification of anti-influenza lead compound targeting at PAC subunit of H5N1 polymerase

PAC subunit from avian influenza (H5N1) viral RNA polymerase was used in this work as a target in the screening for antiinfluenza agents from licorice-derived compounds. As a result, 18b-glycyrrhetinic acid was suggested to be PAC ligand by flexible docking, and was then confirmed by relaxation-edited NMR. The result of ApG primer extension assay indicated that this PAC ligand can inhibit the polymerase activity, and thus may potentially be valuable as anti-influenza lead compound. This work validated the possibility of screening polymerase inhibitors by using PAC as a target, and provided a starting point for the further discovery of new anti-influenza drugs.