mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Framework of automated value stream mapping for lean production under the Industry 4.0 paradigm

For efficient use of value stream mapping (VSM) for multi-varieties and small batch production in a data-rich environment enabled by Industry 4.0 technologies,a systematic framework of VSM to rejuvenate traditional lean tools is proposed.It addresses the issue that traditional VSM requires intensive on-site investigation and replies on experience,which hinders decisionmaking efficiency in dynamic and complex environments.The proposed framework follows the data-information-knowledge hierarchy model,and demonstrates how data can be collected in a production workshop,processed into information,and then interpreted into knowledge.In this paper,the necessity and limitations of VSM in automated root cause analysis are first discussed,with a literature review on lean production tools,especially VSM and VSM-based decision making in Industry 4.0.An implementation case of a furniture manufacturer in China is presented,where decision tree algorithm was used for automated root cause analysis.The results indicate that automated VSM can make good use of production data to cater for multi-varieties and small batch production with timely on-site waste identification and analysis.The proposed framework is also suggested as a guideline to renew other lean tools for reliable and efficient decision-making.
A new species of Zanclognatha Lederer and three new records of the families Erebidae and Noctuidae (Lepidoptera, Noctuoidea) from Korea, with notes on larval feeding habits

A new species of Zanclognatha Lederer, 1857 of the family Erebidae, Z. querciella sp.n., one species of Family Erebidea, Asota egens (Walker, 1854) and two species of Family Noctuidae: Meganephria retinea Gyulai and Ronkay, 1999 and Amphipyra subrigua Bremer and Grey, 1853, are reported for the first time from Korea. In addition, larval feeding habits with their host plants for three species are newly recognized from Korea. Illustration of adults, larvae for Zanclognatha querciella and Meganephria retinea, and the genitalia of male or female for all species are provided.
Changes in and evaluation of surface soil quality in Populus × xiaohei shelterbelts in midwestern Heilongjiang province, China

To examine changes in surface soil quality over time in Populus × xiaohei shelterbelts, we collected soil samples from five shelterbelts of different ages and also from former cropland left fallow for 25 years. Twenty-one surface soil (0-20 cm) properties were measured, and variation in soil quality was assessed using one-way ANOVAs and multiple comparison tests. Based on this analysis, 16 soil indexes were used in a model evaluating soil quality, with each index given weight as determined by the correlation coefficient. Compared with the control, the postmature forest had greater soil moisture content but lower bulk density (P < 0.05). The mature forest also had higher soil pH, total organic carbon, alkali-hydrolyzed nitrogen, available phosphorus, and biomass nitrogen content, but reduced nitrate-nitrogen and total phosphorus content than the control (P < 0.05). Total porosity was highly positively correlated with aeration, nitrate-nitrogen, alkali-hydrolyzed nitrogen, available phosphorus, microbial biomass carbon and microbial biomass nitrogen. Soil total organic carbon, ammonium nitrogen, nitrate-nitrogen, alkali-hydrolyzed nitrogen, total nitrogen, available phosphorus, microbial biomass carbon and microbial biomass nitrogen were all strongly correlated. In the soil quality evaluation model, total organic carbon was assigned the highest weight and total potassium content the lowest. The soil quality index was lowest in the near-mature forest and greatest in the postmature forest. Generally, soil quality in Populus × xiaohei shelterbelts varied with age and was higher in the 10-20 cm versus 0-10 cm soil layer. After a single forest generation, surface soil quality was significantly improved.
Stress response of Lymantria dispar asiatica (Lepidoptera: Erebidae) larvae and its gut microbiota to manganese ion

To study the effect of manganese exposure on the herbivorous insect Lymantria dispar asiatica, fourthinstar larvae were fed a MnCl 2 -amended diet (LdMn) for 84 h (0.40 mmol MnCl 2 /g diet). Larvae were weighed before and after the diet administration to assess larval gain in mass under manganese exposure. The whole bodies of half of the survivors were ground in liquid nitrogen for measuring enzyme activities and total antioxidant capacity (T-AOC). The intestinal tracts of the remaining survivors were collected and immediately frozen in liquid nitrogen for 16S rDNA sequencing of gut microbiota. Larvae under manganese stress lost significant mass (p < 0.05). The activities of digestive and antioxidant enzymes and T-AOC, but not trehalase and polyphenol oxidase, were significantly higher after Mn exposure, (p < 0.05). A Venn diagram illustrated that the gut microbial OTU composition in the larvae also changed. Community pies and correlation heatmaps also showed different relative abundances of gut microbes. In other words, species quantity and relative abundance of gut microbes agreed with PCoA visualization and indicated that the gut microbial community in L. dispar asiatica larvae differed significantly between control and LdMn. Functional classification also suggested that exposure to manganese stress significantly decreased gut microbial coenzyme transport and metabolism in L. dispar asiatica larvae. These results further our understanding about stress response of L. dispar asiatica larvae.
孕期糖代谢异常对脐带间充质干细胞的影响

脐带间充质干细胞(MSC)具有与子代相同的遗传物质且对外界环境较为敏感,可用于评估各种因素对子代早期发育造成的远期影响。越来越多的研究证明来自肥胖及糖代谢异常产妇的脐带MSC存在异常表型,我们重点介绍了孕期糖代谢异常对脐带MSC功能的影响。
青少年双眼特发性中心凹旁毛细血管扩张症继发双眼脉络膜新生血管一例

2型Mac-Tel在亚洲人群中相对少见。本例患者发病年龄小、病情进展快,较为罕见,提示临床该病在青少年人群中也存在一定的患病率,不应忽视。多模式影像可以帮助全面的观察病灶,相较于FFA及OCT, OCTA可分层的特性在诊断该病中更具优势,可以深入观察视网膜深层毛细血管网及外层视网膜,其横断面像及B扫描像可以提供更多病变信息,从而帮助全面明确鉴别、诊断及分型。
茵陈四苓颗粒对急性肝衰竭大鼠肠屏障功能的影响

目的研究茵陈四苓颗粒对急性肝衰竭大鼠模型肠屏障功能的影响。方法将40只SD大鼠随机分为正常组、模型组、阳性对照组(双歧杆菌乳杆菌三联活菌片干预)、中药组(茵陈四苓颗粒干预),予以腹腔注射硫代乙酰胺建立急性肝衰竭大鼠模型,并予以相应药物干预。造模成功48 h后收集腹主动脉血检测大鼠血清AST、ALT、TBIL,HE染色观察大鼠肝肠组织病理,ELISA法测血清DAO、D-LA及炎症因子(IL-6、IL-1β、TNF-α)水平,Western blot检测Occludin及ZO-1蛋白的表达。结果茵陈四苓颗粒可以减缓大鼠体质量下降,抑制AST、ALT、TBIL的升高(P<0.05),降低血清DAO、D-LA及炎症因子IL-6、IL-1β及TNF-α的表达(P<0.05),促进肠组织中Occludin蛋白、ZO-1蛋白的表达(P<0.05)。结论茵陈四苓颗粒可以通过保护急性肝衰竭大鼠肠屏障功能障碍,减轻肠源性内毒素血症,促进肝脏修复。
基于网络药理学及分子对接预测白术-白芍药对治疗肠应激综合征的作用

目的通过网络药理学及分子对接预测白术-白芍药对治疗肠应激综合征(IBS)的药效成分及作用机制。方法借助中药系统药理学分析平台(TCMSP)检索白术、白芍的化学成分及潜在作用靶点,通过人类基因数据库GeneCards查询与IBS相关的靶点。通过R5.3.5软件的VennDiagram和ClusterProfiler包筛选出交集靶点,并进行功能富集和通路分析。采用Cytoscape绘制中药-活性成分-靶点-疾病关系图,并运用AutoDock Vina对成分与靶点进行分子对接验证。结果从白术-白芍药对中筛选得到25个化合物及182个作用靶点,与1 578个IBS相关靶点取交集得到29个作用靶点,靶点映射获得12种活性成分。蛋白相互作用分析结果显示核心靶点有IL-6、MAPK8、CASP3、ESR1、RELA、AhR等。GO分析发现交集靶点具有核受体活性、转录因子活性、类固醇激素受体活性等功能。KEGG分析显示交集靶点可能与AGE-RAGE、TNF等信号通路相关。分子对接结果显示β-谷甾醇与CYP3A4靶点结合自由能最低(-10.3 kcal/mol),芍药苷与AHR受体残基LYS-66、GLU-98、ARG-102、MET-105形成氢键,(+)-儿茶素与AChE受体残基ASN-87、HIS-447、TYR-72形成氢键并与TRP-86残基形成π-π共轭。结论白术-白芍药对中的β-谷甾醇、芍药苷、(+)-儿茶素以及文献报道的白术内酯A、苍术酮、4,15-二羟基环氧白术内酯等活性成分可能通过CYP3A4、AChE、AhR、PTGS1等靶点调节炎症细胞因子及细胞信号转导通路协同治疗IBS。
不同生长期红芪无机元素动态特征探究

目的探究不同生长期红芪中7种无机元素含量的动态特征。方法收集不同生长期(7~10月)红芪样品,采用火焰原子吸收光谱法测定其元素含量,并结合相关性、主成分、正交偏最小二乘法等计量方法分析其规律。结果不同生长期红芪样品元素含量差别显著,4个不同生长期样品可明显分为4类,同时K、Zn含量在10月份时达到最大,Ca、Mg、Fe、Cu在8月份时含量达到最大,Co在9月份时含量达到最大。结论红芪无机元素含量与生长期密切相关,无机元素含量可作为红芪采收期确定的指标之一。
Case study on stratospheric and mesospheric concentric gravity waves generated by deep convection

Concentric gravity waves (CGWs) in the middle and upper atmosphere show wave-coupling processes between the lower atmosphere and the middle and upper atmosphere. In this research, we analyzed a case of CGWs detected simultaneously by the AIRS (Atmospheric Infrared Sounder) and the VIIRS/DNB (Day/Night Band of the Visible Infrared Imager Radiometer Suite) in the stratosphere and mesosphere. Results showed that gravity waves (GWs) were generated by the collocated Hurricane Bejisa on the island of Mauritius. The AIRS data showed arc-like phase fronts of GWs with horizontal wavelengths of 190 and 150 km at 21:08 coordinated universal time (UTC) on 1 January 2014 and at 10:00 UTC on 2 January 2014, whereas the DNB observed arced GWs with horizontal wavelengths of 60 and 150 km in the same geographic regions at 22:24 UTC. The characteristics of CGW parameters in the stratosphere (~40 km) and the mesosphere (~87 km), such as the vertical wavelength, intrinsic frequency, and intrinsic horizontal phase speed, were first derived together with the background winds from ERA5 reanalysis data and Horizontal Wind Model data through the dispersion relationship of GWs and the wind-filtering theory.
Nighttime meridional neutral wind responses to SAPS simulated by the TIEGCM: A universal time effect

The present work uses the Thermosphere Ionosphere Electrodynamics General Circulation Model (TIEGCM), under geomagnetically disturbed conditions that are closely related to the southward interplanetary magnetic field (IMF), to investigate how the nighttime poleward wind (30°-50° magnetic latitude and 19-22 magnetic local time) responds to subauroral polarization streams (SAPS) that commence at different universal times (UTs). The SAPS effects on the poleward winds show a remarkable UT variation, with weaker magnitudes at 00 and 12 UT than at 06 and 18 UT. The strongest poleward wind emerges when SAPS commence at 06 UT, and the weakest poleward wind develops when SAPS occur at 00 UT. A diagnostic analysis of model results shows that the pressure gradient is more prominent for the developing of the poleward wind at 00 and 12 UT. Meanwhile, the effect of ion drag is important in the modulation of the poleward wind velocity at 06 and 18 UT. This is caused by the misalignment of the geomagnetic and geographic coordinate systems, resulting in a large component of ion drag in the geographically northward (southward) direction due to channel orientation of the SAPS at 06 and 18 UT (00 and 12 UT). The Coriolis force effect induced by westward winds maximizes (minimizes) when SAPS commence at 12 UT (00 UT). The centrifugal force due to the accelerated westward winds shows similar UT variations as the Coriolis force, but with an opposite effect.
Characteristic analysis of layered PMSEs measured with different elevation angles at VHF based on an experimental case

Polar Mesosphere Summer Echoes (PMSEs) are very strong radar echoes observed at altitudes near the polar summer mesopause. One of the essential properties of these radar echoes is that they can give useful diagnostic information about the physics of the scattering process. In this paper, the related characteristics of PMSEs measured with the European Incoherent SCATter Very High Frequency (EISCAT VHF) 224 MHz radar on 13-15 July 2010 are studied at different elevation angles from 78° to 90°. It is found that the PMSEs peak power and strongest PMSEs average power occur at the same elevation angles. Also interesting is that the strongest PMSEs occur at off-vertical angles when a PMSEs has a layered (multilayer) structure. And reflection may have more significant effects on PMSEs when there are double or multilayer PMSEs. Possible explanations regarding these observations are discussed.
Evaluation of the immunomodulatory effects of anti-COVID-19 TCM formulae by multiple virus-related pathways

The coronavirus infectious disease 2019 (COVID-19) outbreak is seriously endangering human health. Most patients with severe COVID-19 are characterized by sustained cytokine production and hyper-inflammation, which is known as cytokine storm syndrome. Elaborating the anti-inflammatory response is crucial to these patients, and interleukin-6 (IL6) inhibitors and steroids have been recommended in clinical practice. However, after the cytokine storm phase, the host immune response to sepsis may develop into a protracted immunosuppressive phase. Agents enhancing host immunity administered to patients in the immunosuppressive phase of sepsis could improve survival. Therefore, different treatments should be provided to different COVID-19 patients with cytokine storm phase or immunosuppression phase.
Tuning of active disturbance rejection control for differentially flat systems under an ultimate boundedness analysis: a unified integer-fractional approach

An adaptation of the active disturbance rejection control(ADRC)approach is applied to a fractional-order system with a flat output.Albeit the rather scarce information about the system,the conditions to establish an ultimate bound for a specific configuration of the system are found and compiled in a guideline for the tuning of the observer implemented in the ADRC.
The water-saving potential of using micro-sprinkling irrigation for winter wheat production on the North China Plain

The shortage of groundwater resources is a considerable challenge for winter wheat production on the North China Plain. Water-saving technologies and procedures are thus urgently required. To determine the water-saving potential of using micro-sprinkling irrigation (MSI) for winter wheat production, field experiments were conducted from 2012 to 2015. Compared to traditional flooding irrigation (TFI), micro-sprinkling thrice with 90 mm water (MSI1) and micro-sprinkling four times with 120 mm water (MSI2) increased the water use efficiency by 22.5 and 16.2%, respectively, while reducing evapotranspiration by 17.6 and 10.8%. Regardless of the rainfall pattern, MSI (i.e., MSI1 or MSI2) either stabilized or significantly increased the grain yield, while reducing irrigation water volumes by 20-40%, compared to TFI. Applying the same volumes of irrigation water, MSI (i.e., MSI3, micro-sprinkling five times with 150 mm water) increased the grain yield and water use efficiency of winter wheat by 4.6 and 11.7%, respectively, compared to TFI. Because MSI could supply irrigation water more frequently in smaller amounts each time, it reduced soil layer compaction, and may have also resulted in a soil water deficit that promoted the spread of roots into the deep soil layer, which is beneficial to photosynthetic production in the critical period. In conclusion, MSI1 or MSI2 either stabilized or significantly increased grain yield while reducing irrigation water volumes by 20-40% compared to TFI, and should provide water-saving technological support in winter wheat production for smallholders on the North China Plain.
Evaluation of a povidone-iodine and chitosan-based barrier teat dip in the prevention of mastitis in dairy cows

Postmilking teat dip is an important tool used to prevent mastitis in the modern dairy industry. In this study, we evaluated the in vitro and in vivo efficacies of a barrier teat dip containing povidone-iodine and chitosan for the prevention of mastitis. In experiment 1, we evaluated the antibacterial effects of chitosans with different molecular weights against six mastitis-causing bacteria based on the minimal inhibitory concentration test. The results showed that 50 kDa chitosan had the maximum antibacterial activity compared with 5, 150 and 350 kDa chitosans. In experiment 2, the inhibition zone test indicated that the barrier teat dip with 4.0% povidone-iodine and 1.0% chitosan had higher (P<0.05) in vitro antibacterial efficacy against most tested mastitis-causing bacteria than the barrier teat dip with 4.0% povidone-iodine and no chitosan. In experiments 3 and 4, we evaluated the efficacies of two postmilking teat dips, 1) a barrier teat dip containing 1.0% chitosan and 4.0% povidone-iodine and 2) a conventional nonbarrier product containing 10% povidone-iodine in a field trial at two commercial dairy herds (1 and 2). A 56-d split-udder experiment (experiment 3) was conducted using 47 lactating Chinese Holstein cows in herd 1. Both left teats were immersed in barrier postmilking dip, and both right teats were dipped with nonbarrier postmilking dip. During a 56-d split-herd experiment (experiment 4), a total of 139 lactating Chinese Holstein cows from herd 2 were allocated to two groups: 1) all teats of 67 cows were dipped in the nonbarrier teat dip, and 2) all teats of 72 cows were dipped in the barrier teat dip. Milk samples were collected and analyzed for somatic cell count (SCC), fat content, protein content, and fat-to-protein ratio prior to the start of sampling (0 d), and at 28 and 56 d after initiation. Bacteriological analysis was only performed on milk samples with SCC≥200 000 cells mL-1. In experiment 3, no differences (P>0.05) in SCC, somatic cell score (SCS) or other milk quality indicators were observed between nonbarrier and barrier teat dip treatment teats throughout the experiment. At the end of experiment 4, compared with nonbarrier teat dip group, a reduction (P<0.05) of 29% was observed for subclinical mastitis infection prevalence in the barrier teat dip group. In the barrier teat dip group, the subclinical mastitis infection prevalence on 56 d was lower (P<0.05) than 0 d. No differences (P>0.05) in milk qualities or clinical mastitis incidence were detected between groups. Bacteriological analysis demonstrated that the barrier product containing povidone-iodine and chitosan reduced the subclinical mastitis infection prevalence induced by mastitis pathogens. This effect was mainly due to the reductions in Klebsiella pneumoniae, Pseudomonas aeruginosa, and Escherichia fergusonii infections. Overall, the data indicated that a barrier teat dip containing 4% povidone-iodine and 1% chitosan was more effective than 10% povidone-iodine in preventing subclinical mastitis.
Advancements in plant regeneration and genetic transformation of grapevine (Vitis spp.)

Grapevine (Vitis spp.) is one of the most economically important fruit crops worldwide, and there is considerable interest in improving its major agronomic and enological traits in response to ever-changing agricultural environments and consumer demands. Molecular genetic techniques in particular, associated with rapid technological advancements, provide an attractive alternative to conventional breeding approaches for developing new grapevine varieties with enhanced yield performance, quality, stress tolerance and disease resistance. To date, several grapevine varieties have been transformed with genes associated with diverse functions through biolistic bombardment and/or Agrobacterium-mediated transformation, and transgenic grape lines have been obtained using established regeneration systems. Nevertheless, a wide range of factors, including genotype, explant source and culture medium, have been shown to affect the efficiency of plant regeneration. Moreover, the selection and use of acceptor materials, bacterial strain and cell density, selectable markers and selection methods also influence transformation efficiency. This paper provides an overview of recent advances in grapevine regeneration and genetic transformation and in-depth discussion of the major limiting factors, and discusses promising future strategies to develop robust plant regeneration and genetic transformation in grapevine.
Physical model test and numerical simulation on the failure mechanism of the roadway in layered soft rocks

To explore the failure mechanism of roadway in layered soft rocks, a physical model with the physically finite elemental slab assemblage (PFESA) method was established. Infrared thermography and a video camera were employed to capture thermal responses and deformation. The model results showed that layered soft roadway suffered from large deformation. A three-dimensional distinct element code (3DEC) model with tetrahedral blocks was built to capture the characteristics of roadway deformation, stress, and cracks. The results showed two failure patterns, layer bending fracture and layer slipping after excavation. The layer bending fracture occurred at positions where the normal direction of layers pointed to the inside of the roadway and the layer slipping occurred in the ribs. Six schemes were proposed to investigate the effects of layered soft rocks. The results showed that the deformation of ribs was obviously larger than that of the roof and floor when the roadway passed through three types of strata. When the roadway was completely in a coal seam, the change of deformation in ribs was not obvious, while the deformation in the roof and floor increased obviously. These results can provide guidance for excavation and support design of roadways in layered soft rocks.
Filling the Disaster Data Gap: Lessons from Cataloging Singapore’s Past Disasters

International disaster databases and catalogs provide a baseline for researchers, governments, communities, and organizations to understand the risk of a particular place, analyze broader trends in disaster risk, and justify investments in mitigation. Perhaps because Singapore is routinely identified as one of the safest countries in the world, Singapore’s past disasters have not been studied extensively with few events captured in major global databases such as EM-DAT. In this article, we fill the disaster data gap for postwar Singapore (1950-2020) using specified metrics through an archival search, review of literature, and analysis of secondary sources. We present four key lessons from cataloging these events. First, we expand Singapore’s disaster catalog to 39 events in this time period and quantify the extent of this data gap. Second, we identify the mitigating actions that have followed past events that contribute to Singapore’s present-day safety. Third, we discuss how these past events uncover continuities among vulnerability bearers in Singapore. Last, we identify limitations of a disaster catalog when considering future risks. In expanding the disaster catalog, this case study of Singapore supports the need for comprehensive understanding of past disasters in order to examine current and future disaster resilience.
Extreme space weather events caused by super active regions during solar cycles 21-24

Extreme space weather events including ≥X5.0 flares,ground level enhancement(GLE)events and super geomagnetic storms(Dst≤-250 nT)caused by super active regions(SARs)during solar cycles 21-24 were studied.The total number of ≥X5.0 solar flares was 62,among which 41 were X5.0-X9.9 flares and 21 were ≥X10.0 flares.We found that 83.9% of the ≥X5.0 flares were produced by SARs;78.05% of the X5.0-X9.9 and 95.24% of the ≥X10.0 solar flares were produced by SARs;46 GLEs were registered during solar cycles 21-24,and 25 GLEs were caused by SARs,indicating that 54.3% of the GLEs were caused by SARs;24 super geomagnetic storms were recorded during solar cycles 21-24,and 12 of them were caused by SARs,namely 50% of the super geomagnetic storms were caused by SARs.We ascertained that only 29 SARs produced ≥X5.0 flares,15 SARs generated GLEs and 10 SARs triggered super geomagnetic storms.Of the 51 SARs,only 33 SARs produced at least one extreme space weather event,while none of the other 18 SARs could trigger an extreme space weather event.There were only four SARs and each of them generated not only a ≥X5.0 flare,but also a GLE event and a super geomagnetic storm.Most of the extreme space weather events caused by the SARs appeared during solar cycles 22 and 23,especially for GLE events and super geomagnetic storms.The longitudinal distributions of source locations for the extreme space weather events caused by SARs were also studied.