mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Collapse of Synchronization in a Memristive Network

For an oscillating circuit or coupled circuits, damage in electric devices such as inductor, resistance, memristor even capacitor can cause breakdown or collapse of the circuits. These damage could be associated with external attack or aging in electric devices, and then the bifurcation parameters could be deformed from normal values. Resonators or signal generators are often synchronized to produce powerful signal series and this problem could be investigated by using synchronization in network. Complete synchronization could be induced by linear coupling in a two-dimensional network of identical oscillators when the coupling intensity is beyond certain threshold. The collective behavior and synchronization state are much dependent on the bifurcation parameters. Any slight fluctuation in parameter and breakdown in bifurcation parameter can cause transition of synchronization even collapse of synchronization in the network. In this paper, a two-dimensional network composed of the resonators coupled with memristors under nearest- neighbor connection is designed, and the network can reach complete synchronization by carefully selecting coupling intensity. The network keeps synchronization after certain transient period, then a bifurcation parameter in a resonator is switched from the previous value and the adjacent resonators (oscillators) axe affected in random. It is found that the synchronization area could be invaded greatly in a diffusive way. The damage area size is much dependent on the selection of diffusive period of damage and deformation degree in the parameter. Indeed, the synchronization area could keep intact at largest size under intermediate deformation degree and coupling intensity.
Quantum Entanglement in a Spin-Orbit Coupled Bose-Einstein Condensate

We study the spin-field and the spin-spin entanglement in the ground state of a spin-orbit coupled Bose- Einstein condensate. It is found that the spin-field and the spin-spin entanglement can be induced by the spin-orbit coupling. By mapping the system to the Dicke-like model, the system exhibits a quantum phase transition from a normal (spin balanced) phase to superradiant (spin polarized) phase. The Dicke-like phase transition can be captured by the spin-field and the spin-spin entanglement arising from the spin-orbit coupling. The spin-field and the spin-spin entanglement increase as the Raman coupling increases in the superradiant phase, while they decrease with the Raman coupling increasing in the normal phase. We also consider the effect of a finite detuning on these entanglement show that the presence of the detuning suppresses the spin-field and the spin-spin entanglement.
骨髓涂片和流式细胞术诊断非霍奇金淋巴瘤骨髓侵犯的临床价值比较

目的比较骨髓细胞形态学(BMA)和流式细胞术(FCM)诊断非霍奇金淋巴瘤(NHL)患者骨髓侵犯的临床价值。方法回顾性分析本院在2013~2014年间收治的207例NHL患者的骨髓涂片及流式细胞免疫表型的检测结果,分析2种检测方法在不同程度、不同形态淋巴瘤骨髓侵犯的临床价值。结果经2种方法联合检测,总体阳性率为24.6%(51/207)。BMA和FCM的骨髓侵犯阳性率分别为17.4%(36/207)和22.2%(46/207);其中阳性结果一致者29例,主要表现于高比例瘤细胞骨髓侵犯的病例;不一致36例多见于低比例瘤细胞骨髓侵犯的病例(17.4%),16例FCM检测为阳性而BMA为阴性的病例主要为轻度异形小细胞淋巴瘤,8例BMA阳性而FCM为阴性的病例为高度异形大细胞淋巴瘤。结论BMA、FCM在诊断不同形态淋巴瘤细胞侵犯的敏感性不同,FCM诊断轻度异形细胞淋巴瘤骨髓侵犯的敏感性高于BMA,BMA检测高度异型大细胞淋巴瘤骨髓侵犯优于FCM,两者联合检测可提高骨髓侵犯的阳性率。
An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014

I entered the Rega Institute for Medical Research in August 1964, as a medical student, to start working under the guidance of Prof. Piet De Somer, then professor of microbiology at the Leuven School of Medicine. When I graduated as medical doctor (MD) in 1966, I hesitated between a clinical career in Internal Medicine or a scientific career in experimental research, the latter under the tutorship of Prof. De Somer who persuaded me to work on interferon (inducers). The discovery of the interferon-inducing capacity of double-stranded RNAs, such as poly(I) ? poly(C), by Maurice Hille-man's group at Merck in 1967 would prove of key importance in my decision to engage in interferon research. In 1968 I described the induction of interferon by polyacrylic acid and polymethylacrylic acid; one year after Thomas C. Merigan at Stanford University had described interferon induction by pyran copolymer. As a postdoctoral fellow at Stanford (from 1968 till 1970), I discovered, with T.C. Merigan, several new polynucleotides as inducers of interferon. Upon my return to Leuven at the end of 1970, I picked up a new line of research, that of the reverse transcriptase (RT), which had just been discovered by Temin (and Mizutani) and Baltimore. In 1975 I then discovered suramin as a potent RT inhibitor (published in 1979), and this prompted Mitsuya and his colleagues (including R.C. Gallo and S. Broder) to evaluate suramin as a potential anti-HIV agent.
Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9

RBPjk-dependent Notch signaling regulates both the onset of chondrocyte hypertrophy and the progression to terminal chondrocyte maturation during endochondral ossification. It has been suggested that Notch signaling can regulate Sox9 transcription, although how this occurs at the molecular level in chondrocytes and whether this transcriptional regulation mediates Notch control of chondrocyte hypertrophy and cartilage development is unknown or controversial. Here we have provided conclusive genetic evidence linking RBPjk-dependent Notch signaling to the regulation of Sox9 expression and chondrocyte hypertrophy by examining tissuespecific Rbpjk mutant (Prx1Cre;Rbpjk~(f/f)), Rbpjk mutant/Sox9 haploinsufficient (Prx1Cre;Rbpjk~(f/f);Sox9~(f/+)), and control embryos for alterations in SOX9 expression and chondrocyte hypertrophy during cartilage development. These studies demonstrate that Notch signaling regulates the onset of chondrocyte maturation in a SOX9-dependent manner, while Notch-mediated regulation of terminal chondrocyte maturation likely functions independently of SOX9. Furthermore, our in vitro molecular analyses of the Sox9 promoter and Notch-mediated regulation of Sox9 gene expression in chondrogenic cells identified the ability of Notch to induce Sox9 expression directly in the acute setting, but suppresses Sox9 transcription with prolonged Notch signaling that requires protein synthesis of secondary effectors.
Consumers’ perceptions on GM food safety in urban China

The debate about the safety of genetically modified (GM) food has attracted public attention in concurrence with the rapid development of agricultural biotechnology. This paper examines the consumers’ perceptions on the safety of GM food in China. Based on a unique survey dataset, this study shows that consumers in urban China have significantly changed their perceptions on GM food safety. The percentage of consumers who perceived such food as unsafe for consumption increased by more than 30% in the 2002–2012 period. Approximately half of the consumers did not have an opinion on this issue. Major shifts have been occurred after 2010, likely because of the increasing influence of negative media reports on GM technology in recent years. Several individual and household’s characteristics are shown to significantly affect consumers’ perceptions on GM food safety, such as gender, education, food allergy experience and resident city size. The paper concludes with policy implications.
首诊眼科的虹膜转移癌一例

本例患者初诊时误诊为虹膜睫状体炎及前房积血,一定程度上延误了治疗时机。本例患者提示我们在临床工作中应注意:(1)详细进行专科检查、全身体格检査和询问病史。虹膜肿物位于眼前节,裂隙灯显微镜下易发现病灶,对于由虹膜睫状体炎、青光眼症状且经相关治疗效果欠佳者应详细检查患者的病史和全身表现。(2)充分利用超声生物显微镜(ultrasound biomicroscopy,UBM)检查。UBM能清楚显示虹膜前后和睫状体区肿物。本例患者早期有虹膜炎、前房积血等症状,但可能病灶较小且有前房积血而疏漏了相关检查,来诊时瘤体大,推测初诊时已有虹膜转移癌。(3)对于无外伤史的前房积血、青光眼患者应引起重视并行UBM检査,以发现是否有新生物或肿瘤坏死组织脱落并堵塞房角。(4)应注意与植人性虹膜囊肿、虹膜黑色素瘤及一些原发性虹膜肿瘤等相鉴别。植人性虹膜囊肿内含物对葡萄膜有刺激作用,可并发虹膜睫状体炎;部分虹膜黑色素瘤患者晚期因肿瘤坏死而继发前葡萄膜炎或前房积血,肿瘤坏死组织脱落堵塞房角而出现继发青光眼症状。 本例患者瘤体表面不光滑,无色素,可见新生血管,且患者无眼部创伤史,应高度怀疑虹膜转移癌,活体组织病理学检查可确诊。(5)适时选择影像学检查手段。许多恶性肿瘤患者以转移灶症状首诊于相关科室,眼科医师遇到虹膜肿瘤患者应注意寻找病因,对患者进行详细专科检查的同时应注意全身检查,避免误诊和漏诊,对恶性肿瘤患者做到早期诊断和及时治疗,延长患者的生存时间。
Fruit fly courtship: The female perspective

Research on fruit fly courtship has mostly focused on males' behavioral repertoire whereas females have been as sumed to respond by either rejecting or accepting males. In many fruit fly species including Drosophila melanogaster, however mating typically follows an extended period of courtship, which provides ample opportunities for females to inform males abou their likelihood of mating. Our experiments indeed revealed that sexually immature females in both D. melanogasterand D. si-rnulans showed responses to conspecific males that were distinct from those of sexually mature females. Furthermore, females responses to conspecific males were different from their responses to heterospecific males. Our data indicate that females' beha vioral repertoire early in courtship can inform males about their probability of mating if they persist in courting. We hypothesize (i) that males can rely on behavioral feedback from females for optimally allocating their courtship efforts towards distinct female classes, (ii) that males may learn to modulate their courtship behavior based on specific feedback from females, and (iii) that fe males may learn to alter their behavior towards distinct types of males in order to elicit the desired male response. Overall, we suggest that, although little explored, female behavior determines the dynamics of courtship and mating and can thus influence sexual selection and incipient speciation.
Male Drosophila melanogaster learn to prefer an arbitrary trait associated with female mating status

Although males are generally less discriminating than females when it comes to choosing a mate, they still benefit from distinguishing between mates that are receptive to courtship and those that are not, in order to avoid wasting time and energy. It is known that males of Drosophila melanogaster are able to learn to associate olfactory and gustatory cues with female receptivity, but the role of more arbitrary, visual cues in mate choice learning has been overlooked to date in this species. We therefore carried out a series of experiments to determine: 1) whether males had a baseline preference for female eye color (red versus brown), 2) if males could learn to associate an eye color cue with female receptivity, and 3) whether this association disappeared when the males were unable to use this visual cue in the dark. We found that naive males had no baseline preference for females of either eye color, but that males which were trained with sexually receptive females of a given eye color showed a preference for that color during a standard binary choice experiment. The learned cue was indeed likely to be truly visual, since the preference disappeared when the binary choice phase of the experiment was carried out in darkness.This is, to our knowledge 1) the first evidence that male D. melanogaster can use more arbitrary cues and 2) the first evidence that males use visual cues during mate choice learning. Our findings suggest that that D. melanogaster has untapped potential as a model system for mate choice learning.
Temperature increase impacts personality traits in aquatic non-native species: Implications for biological invasion under climate change

Climate change, such as elevated temperatures, may facilitate biological invasion. Aquatic animal systems are more vulnerable to biological invasion when the temperature rises. Animal personality also plays an important role in the possibility of successful establishment of invasive species. However, it is still unclear how personality traits of invasive species will respond to global warming. This study focuses on juveniles of red swamp crawfish Procambarus clarkii, an invasive poikilothermic species with wide distribution throughout the world, and explores how slight temperature increases influence three personality traits (activity, boldness and aggressiveness) of P. clarkii. For each personality, individual variation is to be presented in condition of the same temperature. Individual personality values can significantly increase with the subtle rising of water temperature. Significant correlations among activity, boldness and aggressiveness are found at any temperature stage, and such relationships are maintained at a similar level in the face of different temperatures. It is most likely that significant expressions of personality traits may be an ecological compensation strategy to offset increased metabolic costs when faced with small temperature increases. Aggression syndromes are formed due to stable linkages between personality traits, in order to acquire allopatric resources efficiently and establish a new population in this species.
The BPP program for species tree estimation and species delimitation

This paper provides an overview and a tutorial of the BPP program, which is a Bayesian MCMC program for analyzing multi-locus genomic sequence data under the multispecies coalescent model. An example dataset of five nuclear loci from the East Asian brown frogs is used to illustrate four different analyses, including estimation of species divergence times and population size parameters under the multispecies coalescent model on a fixed species phylogeny (A00), species tree estimation when the assignment and species delimitation are fixed (A01), species delimitation using a fixed guide tree (A10), and joint species delimitation and species-tree estimation or unguided species delimitation (A11). For the joint analysis (A11), two new priors are introduced,which assign uniform probabilities for the different numbers of delimited species, which may be useful when assignment,species delimitation, and species phylogeny are all inferred in one joint analysis. The paper ends with a discussion of the assumptions, the strengths and weaknesses of the BPP analysis.
合肥市两所高校大学生艾滋病知识、态度、行为的调查

目的了解合肥市两所高校大学生艾滋病相关综合防治知识知晓及态度、行为现状,为更加有效地开展大学生艾滋病宣传干预提供研究依据。方法选择合肥市两所高校,采取随机整群抽样方法,对2 673名在校大学生的艾滋病知识、态度、行为进行问卷调查。结果大学生艾滋病知识知晓率为84.0%,男生知晓率高于女生,差异有统计学意义(χ~2= 37.199,P <0.001);不同年级、专业、地区的学生知晓率差异均有统计学意义(均有P<0.05)。有过性行为的比例为7.7%;首次性行为使用安全套比例为64.9%;在固定性伴及临时性伴中最近1次性行为使用安全套比例分别为62.2%和54.4%,最近1年性行为"每次都用安全套"的比例均低于40.0%。结论大学生人群艾滋病知识知晓率总体尚好,但有个别知识点知晓率较低,部分学生有不安全的性行为,且自我防护意识薄弱。在今后的艾滋病健康教育工作中要注重系统化教育,把态度行为的改变作为重点。
Fetal alcohol spectrum disorder: molecular insights into neural damage reduction

Fetal alcohol spectrum disorders (FASD) is a group of entirely preventable, lifelong conditions, which occur upon maternal alcohol use during pregnancy. This can result in severe consequences for the newborn and ultimately the family. It is usually characterized by delays in development and motor function, craniofacial abnormalities, and difficulties with learning, memory, speech, and academic achievement. According to the German guidelines for fetal alcohol syndrome (FAS) diagnosis, the prevalence of FASD ranges between 0.02–0.8% of all annual births and often the disorder is not recognized (Landgraf et al., 2013). The U.S. National Institutes of Health regard FAS as the most common nonhereditary cause of mental retardation. Thus, preventing programs, like the one undertaken by the Australian Government, which appointed a National FASD Technical Network (Elliott, 2015), may seem a very reasonable strategy. However, preventing programs for FASD focus mainly either on primary prevention, by increasing pregnant women's awareness of ethanol consumption risks, or on tertiary prevention which supposes early recognition of the condition and social support in the form of an improved developmental framework of the affected individual. Secondary prevention of the disorder, which includes early detection by screening pregnant women for ethanol consumption and control of the progression from a preclinical pathological condition to a severe form of the disease, is considered to be most challenging (Elliott, 2015). Although the most important form of prevention is abstinence from alcohol during pregnancy, offsprings from women with known gestational alcohol misuse could still benefit from a secondary form of FASD prevention, which might hinder the progression to FAS. However, therapy approaches are precluded by our limited knowledge of molecular mechanisms responsible for neuronal damage.
Brain protection against ischemic stroke using choline as a new molecular bypass treatment

Aim: To determine whether administration of choline could attenuate brain injury in a rat model of ischemic stroke and the underlying mechanisms. Methods: A rat model of ischemic stroke was established through permanent middle cerebral artery occlusion (pMCAO). After the surgery, the rats were treated with choline or choline plus the specific α7 nAChR antagonist methyllycaconitine (MLA), or with the control drug nimodipine for 10 days. The neurological deficits, brain-infarct volume, pial vessel density and the number of microvessels in the cortex were assessed. Rat brain microvascular endothelial cells (rBMECs) cultured under hypoxic conditions were used in in vitro experiments. Results: Oral administration of choline (100 or 200 mg?kg~(-1)?d~(-1)) or nimodipine (20 mg?kg~(-1)?d~(-1)) significantly improved neurological deficits, and reduced infarct volume and nerve cell loss in the ischemic cerebral cortices in pMCAO rats. Furthermore, oral administration of choline, but not nimodipine, promoted the pial arteriogenesis and cerebral-cortical capillary angiogenesis in the ischemic regions. Moreover, oral administration of choline significantly augmented pMCAO-induced increases in the expression levels of α7 nAChR, HIF-1α and VEGF in the ischemic cerebral cortices as well as in the serum levels of VEGF. Choline-induced protective effects were prevented by co-treatment with MLA (1 mg?kg~(-1)·d~(-1), ip). Treatment of rBMECs cultured under hypoxic conditions in vitro with choline (1,10 and 100 μmol/L) dose-dependently promoted the endothelial-cell proliferation, migration and tube formation, as well as VEGF secretion, which were prevented by co-treatment with MLA (1 μmol/L) or by transfection with HIF-1α siRNA. Conclusion: Choline effectively attenuates brain ischemic injury in pMCAO rats, possibly by facilitating pial arteriogenesis and cerebral-cortical capillary angiogenesis via upregulating α7 nAChR levels and inducing the expression of HIF-1α and VEGF.
胸壁间叶来源肉瘤的外科治疗

胸壁低度恶性纤维黏液样肉瘤、恶性纤维组织细胞瘤属于胸壁间叶来源肉瘤,临床较少见,放化疗效果较差,多需外科手术治疗。回顾性分析我院2003年1月至2011年3月收治的9例胸壁肉瘤患者的临床资料,总结该病的外科治疗经验,进一步提高其治疗水平。
TrinseoPC医疗产品广泛应用于医疗行业

塑料已应用在人们生活的各个领域。医疗器械在对人类疾病的诊断、治疗、监护、保健、康复、生殖健康方面发挥着重要作用,而其中的塑料制品是不可或缺的重要组成部分,我们称之为医用塑料制品。随着现代科学和医疗技术的迅速发展,医疗器械作为科学技术产品重要标志之一,已成为医学领域的重要环节。医用塑料制品具有高技术含量、高附加值的特点,其发展极具潜力。医用塑料发展一直保持20%左右的年增长率,其发展态势已可以与信息产业和汽车工业相比。医用塑料制品的需求大增也带动其原料需求。
Synthesis and Electrochemical Properties of a Novel Poly(ether sulfone) with Oligoaniline Pendants

A novel poly(ether sulfone) with oligoaniline pendants(PESOP) was prepared by K_2CO_3-mediated nucleophilic polycondensation and characterized with Fourier-transform infrared spectrometry(FTIR), ~1H nuclear magnetic resonance(~1H NMR) and gel permeation chromatography(GPC). The cyclic voltammetry(CV) curve of PESOP reveals the reversible electroactivity. In the electrochromism study, PESOP film exhibited good electrochromic properties with a high contrast value, moderate switching time and acceptable coloration efficiency. After running 1000 cycles, the PESOP/indium-tin oxide(ITO) electrochromic device remained unchanged except for the drifting of base line, which certified its good electro-photo stability of the fabricated electrochromic device. Moreover, the polarization technique and electrochemical impedance spectroscopy(EIS) were used to study the anticorrosion performance of PESOP coatings on the cold rolled steel(CRS) in a 5%(mass fraction) NaCl solution. All the results indicate that the obtained PESOP is a competitive candidate as anticorrosion material.
内香7A高位分蘖与灌水深度和赤霉素施用的关系研究

就内香7A生育后期高位分蘖问题,设计了2因素(灌水深度和赤霉素施用时间)的栽培试验,对各处理下高位分蘖比例和高位分蘖长度进行统计和方差分析。结果表明:灌水深度对内香7A生育后期的高位分蘖比例有显著影响,对高位分蘖长度无显著影响;赤霉素施用时间对高位分蘖比例和长度均有显著影响。根据该试验,得出了控制内香7A高位分蘖的最佳措施,即内香7A在叶枕平后田间灌水深度至少3 cm,同时在见穗1%~5%时喷施赤霉素。该措施经过2014年在梓潼县制种生产应用验证,其高位分蘖比例可控制在5%以下,且增产效果十分显著。
两系杂交稻制种风险及其控制

根据2000年以来15 a盐城大面积两系杂交稻制种中遭遇的4 a低温危害,分析育性敏感期低温对所产杂交种子质量的影响,以及不同不育系对低温的反应程度,结合当地1985年以来的30 a气象资料,表明这4 a出现不同程度的质量危害,是由于制种选用的不育系在育性敏感期不能抵御连续3 d日平均气温低于23.5℃的低温,以及安排的花期不合理造成的。在盐城地区控制两系杂交稻制种风险的对策是:选用的不育系在育性敏感期要具有抵御连续3 d日平均气温低于23.5℃低温的能力,基地选择在盐城中部的里下河和沿海地区,不育系育性敏感期安排在7月25日至8月10日,抽穗扬花初期在8月15-20日,同时要注重培植生育期一致的群体,主动抗灾应变,强化制种行业管理。
20号染色体长臂部分缺失骨髓增生异常综合征30例临床特征分析

20号染色体长臂部分缺失[del(20q)]被公认为骨髓增生异常综合征(MDS)预后好的核型,但仍有研究得出相反的结论,认为此型生存期短,转白率比预期的高。本文回顾性分析广东省人民医院del(20q)MDS患者临床、血液学和预后资料,现报道如下。
产前超声诊断胎儿右心房异构综合征的应用价值

内脏异构综合征是胚胎期内脏分侧性异常累及腹腔、胸腔多个器官的复杂畸形。根据侧别趋向的不同,内脏异构综合征分为左房异构综合征和右房异构综合征(right atrial isomerism syndrome,RAIS)。胎儿RAIS复杂且极为少见,关于RAIS的产前超声诊断报道不多,本研究分析总结胎儿RAIS的产前超声特点,探讨产前超声对胎儿RAIS的诊断价值。
Objective System and Coordination Mechanism Design for “Multi-Planning System Integration”

One of the hot issues to realize the multi-planning system integration is to explore the inter-planning coordination mechanism breaking current technical and system restrictions. The essence of planning disintegration is the disconnection of their objective system, indicator system, and spatial coordinate system. Few studies have been conducted on this issue. This paper analyzes the manifestations and causes of the “three-system dissociation,” and proposes to establish a new objective system. In addition, it proposes to strengthen the connection design, aiming to explore effective ways to realize inter-planning connection and coordination.
鳃裂癌一例

鳃裂癌(branchiogenic carcinoma)是源于鳃裂囊肿(branchial cleft cyst)内衬上皮癌变,绝大多数为鳞状细胞癌,极少数为黏液表皮样癌,其发病率极低,目前已报道病例不足40例。因出现颈侧部囊性病变的疾病种类很多,如囊性坏死性神经鞘瘤、淋巴结坏死性肉芽肿性炎、淋巴管瘤、静脉畸形、淋巴瘤伴囊性变以及头颈部的转移性囊性鳞状细胞癌等,易与鳃裂癌混淆,所以该病的病理诊断常在术后经全面仔细的组织学检查后才能做出,且是一种排除性的病理诊断。内蒙古医科大学附属医院曾收治1例鳃裂癌,现报道如下。
甘肃省平凉汉族群体19个STR基因座遗传多态性

本研究对中国甘肃地区平凉市汉族217名健康无关个体进行19个STR基因座遗传多态性调查。采用Chelex-100法提取样本DNA,用AGcUEX 20 STR试剂盒进行扩增及检测。结果在19个STR基因座共检测出194个等位基因,其分布符合Hardy-Weinberg平衡定律(P>0.05)。所调查的汉族人群19个STR基因座具有较好识别能力。
排尿日记的发展及其对儿童夜遗尿诊断的重要性

儿童夜遗尿(又称遗尿症,enuresis)是一种常见疾病,虽不会对患儿造成急性伤害,但长期的夜间遗尿往往会给患儿及其家庭带来严重的疾病负担和心理压力。研究发现,约0.5%~2%的患儿遗尿症状可持续至成年期。因此,儿童夜遗尿应尽早确诊并及时治疗。目前,夜遗尿临床诊断途径主要有病史采集、体格检查、实验室检查和排尿日记(urinary diaries)。排尿日记作为一种非侵入性诊断工具,不仅增加了患儿就诊的依从性,还能动态、客观地反映病情,并有助于区分全天多尿、夜间多尿、压力性尿失禁及急迫性尿失禁等,准确判断患儿夜遗尿类型,指导临床针对性治疗。
对徐国宾、杨志达两先生某些论点的再讨论

笔者在文献[1]中对徐、杨两先生在文献[2]中涉及到笔者的某些论点进行了讨论,徐、杨两先生以文献[3]对[1]作了答复。由文献[1]之"1问题的起源"部分可知,这一讨论实际上在文献[4]的第6章之§6.7中已经开始。
鼻腔睾丸核蛋白中线癌累及眼眶一例

NUT中线癌是近年来人们刚刚认识到的一种有独特分子遗传学改变的实体肿瘤,此肿瘤病程进展凶险,目前尚未建立特异性的治疗方案,手术切除仍是目前主要的治疗方式,并结合放化疗等辅助治疗。随访过程中,患者目前未出现复发或转移的临床证据。随着对此肿瘤的关注及研究的深入,相信有更多的病例会被相继发现,它的发生部位、组织学形态、细胞起源、分子遗传学改变机制、治疗及预后等特点仍需进一步的研究及探讨。
外用卡替洛尔成功治疗儿童丛状血管瘤和化脓性肉芽肿

目前婴儿血管瘤治疗手段丰富,疗效大多满意。而丛状血管瘤、化脓性肉芽肿等儿童获得性血管瘤治疗手段较单一,常为有创治疗。化脓性肉芽肿多采用CO_2激光、冷冻或手术等,而丛状血管瘤因其持续增长,多种治疗不满意,常需手术切除。我们外用2%盐酸卡替洛尔滴眼液(商品名:美开朗,中国大冢制药有限公司)成功治疗儿童丛状血管瘤和化脓性肉芽肿各1例。
基于肌音信号的上肢康复训练动作模式识别方法

研究表明,建立受损大脑与障碍肢体运动间的联系是加速恢复肢体功能的有效办法,而生物反馈则是借助精密的专业工具,探查和放大人体固有的生理变化过程中所产生的各种信息,通过显示系统将此种信息转变为易于为患者理解的信号或读数,在医务人员的指导下进行训练,使患者学会利用经过处理的自身信号,有意识地控制体内各种生理、病理的过程。上肢功能康复是康复治疗的难题之一,而可靠的生物信号源的采集及其模式识别则是上肢康复训练机器人的关键之一。目前,可作为控制源的人体生物信号有肌电信号、肌音信号、脑电信号等。肌音信号作为一种机械振动信号,具有抗干扰性强、采集操作要求低、不受生理现象影响等优点,与肌电信号和脑电信号相比,肌音信号在肌肉收缩疲劳时具有更高的准确率。
可调式多功能踝足矫形器在早期脑损伤足下垂中的应用

目的观察自主研发可调式多功能踝足矫形器对脑损伤早期卧床患者踝关节功能的影响。方法采用随机数字表法将60例脑损伤早期卧床患者分为观察组及对照组,2组患者均给予基础康复治疗,观察组患者在此基础上穿戴我科自主研发的可调式多功能踝足矫形器。于治疗前、治疗1周、2周及3周时观察2组患者踝关节活动度情况。结果治疗1周后发现观察组患者踝关节活动范围[(9.20 ±3.07)°]较治疗前明显改善(P <0.05),而对照组此时踝关节活动范围较治疗前无明显改善(P> 0.05);治疗2周、3周时发现观察组患者踝关节活动范围[分别为(13.67 ±2.56)°、(20.50 ±3.91)°]及对照组踝关节活动范围[分别为(10.93 ±3.20)°、(15.93±2.75)°]均较治疗前明显改善(P<0.05),并且上述时间点观察组患者踝关节活动范围亦显著优于对照组水平(P <0.05)。结论该自主研发可调式多功能踝足矫形器可有效改善脑损伤患者踝关节控制能力,为患者步行训练奠定基础。