mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Synthesis,Crystal Structure and Electrochemistry Properties of an Iron(Ⅲ) Complex Based on the 3,5-Pyridinedicarboxylate and Water Ligands

Reaction of 3,5-pyridine-dicarboxylie acid (3,5-PydcH_2) with iron salt in hydrothermal condition results in the formation of a three-dimensional self-assembly network formulated as [C_(14)H_(14)Fe_2N_2O_(12)]_n, and it has been structurally characterized by elemental analysis, IR spectra and X-ray diffraction. It crystallizes in the monoclinic system, space group C2/c with α =9.9633(15), b = 12.0942(18), c = 7.4297(11) (A) and β= 105.822°. The units of Fe_2(pydc)_2·2H_2O are linked into a one-dimensional structure via the chelate earboxylate groups from the 3,5-pyridine-diearboxylate. The interlayer hydrogen bonding interactions result in a three-dimensional supramolecular architecture. In the complex, the Fe(Ⅲ) ion displays a slightly distorted pentagonal bipyramidal geometry with seven coordination numbers. Cyelie-voltammetry measurement reveals the oxidation and reduction processes for the complex are quasi-reversible in nature.
新生儿巨大肝囊肿一例

患儿:男,生后半小时因腹胀、呼吸困难而入院.患儿系G1P1,孕期6个月,产前B超检查提示胎儿腹内有一巨大囊性肿块.未发现有其他畸形而继续妊娠.满.38周时因羊水增多,羊膜早破而人院行剖腹产,出生体重4.25 kg,生后发现腹部膨隆,哭声低弱伴气促、呼吸困难由产科转入外科治疗.腹部增强CT示腹腔内巨大囊性占位,肝、脾、肠道受压移位.
Structural insights into a novel histone demethylase PHF8

Dynamic regulation of histone methylation/demethylation plays an important role during development. Muta-tions and truncations in human plant homeodomain (PHD) finger protein 8 (PHF8) are associated with X-linked mental retardation and facial anomalies, such as a long face, broad nasal tip, cleft lip/cleft palate and large hands, yet its molecular function and structural basis remain unclear. Here, we report the crystal structures of the catalytic core of PHF8 with or without α-ketoglutarate (α-KG) at high resolution. Biochemical and structural studies reveal that PHF8 is a novel histone demethylase specific for di- and mono-methylated histone H3 lysine 9 (H3K9me2/1), but not for H3K9me3. Our analyses also reveal how human PHF8 discriminates between methylation states and achieves sequence specificity for methylated H3K9. The in vitro demethylation assay also showed that the F279S mutant ob-served in clinical patients possesses no demethylation activity, suggesting that loss of enzymatic activity is crucial for pathogenesis of PHF8 patients. Taken together, these results will shed light on the molecular mechanism underlying PHF8-associated developmental and neurological diseases.
Nonlinear adaptive observer-based sliding mode control for LAMOST mount driving

Heavy disturbances caused mainly by wind and friction in the mount drive system greatly impair the pointing accuracy of the Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST). To overcome this negative effect, a third order Higher Order Sliding Mode (HOSM) controller is proposed. The key part of this ap-proach is to design an appropriate observer which obtains the acceleration state. A nonlinear adaptive observer is proposed in which a novel polynomial model is applied to estimate the internal disturbances of the mount drive system. Theoretical analy-sis demonstrates the stability of the proposed observer. Simulation results show that this nonlinear adaptive observer can obtain a high precision acceleration signal which completes the HOSM controller. Furthermore, the HOSM approach can easily satisfy the position tracking requirements of the LAMOST mount drive system.
Spatial Variability of Soil Organic Carbon Under Maize Monoculture in the Song-Nen Plain,Northeast China

Soil organic carbon (SOC) and its relationship with landscape attributes are important for evaluating current regional,continental,and global carbon stores.Data of SOC in surface soils (0-20 cm) of four main soils,Cambisol,Arenosol,Phaeozcm,and Chernozem,were collected at 451 locations in Nongan County under maize monoculture in the Song-Nen Plain,Northeast China.The spatial characteristics of soil organic carbon were studied,using geographic information systems (GIS) and geostatistics.Effects of other soil physical and chemical properties,elevation,slope,and soil type on SOC were explored.SOC concentrations followed a normal distribution,with an arithmetic mean of 14.91 g kg~(-1).The experimental variogram of SOC was fitted with a spherical model.There were significant correlations between soil organic carbon and bulk density (r=-0.374~(**)),pH (r=0.549~(**)),total nitrogen (r=0.781~(**)),extractable phosphorus (r=-0.109~*),exchangeable potassium (r=0.565~(**)),and cation exchange capacity (r=0.313~(**)).Generally,lower SOC concentrations were significantly associated with high elevation (r=-0.429~(**)).Soil organic carbon was significantly negatively correlated with slope gradient (r=-0.195~(**)).Samples of the Cambisol statistically had the highest SOC concentrations,and samples of the Arenosol had the lowest SOC value.
Elemental Sulfur Oxidation by Thiobacillus spp.and Aerobic Heterotrophic Sulfur-Oxidizing Bacteria

The prediction of the oxidation rate of elemental sulfur (S~0) is a critical step in sulfur (S) fertilizer strategy to supply plant-available sulfur.An incubation experiment was conducted to determine the rate and amount of S~0 oxidation in relation to the contribution of Thiobacillus spp. and aerobic heterotrophic S-oxidizing bacteria.After 84 days,16.3% and 22.4% of the total S~0 applied to the soil were oxidized at 20 and 30℃,respectively.The oxidation of S~0 proved to be a two-step process with a rapid oxidation during the first 28 days and a slow oxidation from then on. The highest oxidation rate of 12.8 μg S cm~(-2) d~(-1) was measured during the first two weeks at 30℃.At 20℃ the highest oxidation rate of 10.2 μg S cm~(-2) d~(-1) was obtained from two to four weeks after start of the experiment.On an average the soil pH declined by 3.6 and 4.0 units after two weeks of experiment.At the same time the electric conductivity increased nine times.With the oxidation of S~0 the population of ThiobaciUus spp.and aerobic heterotrophic S-oxidizing bacteria increased.The corresponding values for Thiobacillus spp.and aerobic heterotrophic S-oxidizing bacteria increased from 2.9×10~5 and 1.4×10~5 g~(-1) soil at the start of the experiment to 4×10~8 and 5.6×10~8 g~(-1) soil 14 days after S~0 application,respectively.No Thiobacillus spp.was present eight weeks after S~0 application.The results suggested that oxidation of residual S~0 completely relied on aerobic heterotrophic S-oxidizing bacteria.
Isolation and Characterization of a Bensulfuron-Methyl Degrading Strain L1 of Bacillus

The objectives of this study were to isolate a bensulfuron-methyl (BSM)-degrading strain of Bacillus spp.and to evaluate its effectiveness in remediation of a BSM-contaminated soil.A BSM-degrading bacterium,strain L1,was successfully isolated in this study. Strain L1 was identified as Bacillus megaterium based on its morphological,physiological,and biochemical properties,G+C content,phylogenetic similarity of 16S rDNA,and fatty acid composition.Two experiments were used to examine BSM degradation by strain L1.When BSM was used as a sole carbon source in a mineral salt medium,the average degradation rate of BSM by strain L1 was 12.8%,which suggested that the strain was able to utilize BSM as a sole carbon and energy source.Supplement of yeast extract (200 mg L~(-1)) significantly (P≤0.01) accelerated the degradation of BSM by strain L1.Almost complete degradation (97.7%) of BSM could be achieved in 84 h with addition of yeast extract.In addition,in a sterile soil with 50 mg L~(-1) BSM,BSM degradation rate by strain L1 was 94.3% in 42 d,indicating the potential of using microbes for the remediation of BSM-contaminated soils in fields.
Wetting Rate and Clay Content Effects on Interrill Erosion in Ultisols of Southeastern China

An aggregate stability test and a simulated rainfall test were conducted on four representative Ultisols from southeastern China.The soils selected,with clay contents ranging between 117 and 580 g kg~(-1),were derived from shale and Quaternary red clay.The stability of aggregates (2-5 mm in diameter) obtained from the soil samples were determined by the Le Bissonnais method.For determination of infiltration,runoff,and erosion,the soil samples were packed in 30 cm×60 cm trays,wetted at rates of 2,10,and 60 mm h~(-1),and then exposed to simulated rainfall at 60 mm h~(-1) for 1 h.The results indicated that both aggregate stability and slaking caused by fast wetting increased with increasing clay content.The effect of wetting rate (WR) on infiltration and seal formation varied with clay contents.In the soil with low clay content (sandy loam),the infiltration rate was affected slightly by WR due to low aggregate stability and slaking.In the soils with medium clay content (silt clay loam and clay),WR affected infiltration significantly due to the high aggregate slaking force.In the soil with high clay content,the effect of WR on infiltration was significant,but not as evident as in the soils with medium clay content,which may be related to high aggregate stability by wetting partially compensating for slaking force.The effect of WR on soil loss was similar to that of runoff,but more pronounced.The findings from this study indicated that the relationship between wetting rate and clay content should be considered when predicting interrill erosion in Ultisols.
DECAY RATES OF PLANAR VISCOUS RAREFACTION WAVE FOR MULTI-DIMENSIONAL SCALAR CONSERVATION LAW WITH DEGENERATE VISCOSITY ON HALF SPACE

We investigate the decay rates of the planar viscous rarefaction wave of the initial-boundary value problem to scalar conservation law with degenerate viscosity in several dimensions on the half-line space,where the corresponding one-dimensional problem admits the rarefaction wave as an asymptotic state.The analysis is based on the standard L2-energy method and L~1-estimate.
构建我国农村环境污染防治法律体系的思考

农村环境污染危害严重,治理难度大,必须综合采用多种手段才能有效进行防治,法律手段是各种手段的前提和基本保障.我国防治农村环境污染的法律规定比较少,对污染防治造成极大困难.加快农村环境污染防治方面的立法,构建较为完善的法律体系,可以为保护农村环境,防治环境污染创造有利的条件.
广东省耕地资源保护利用现状和对策

综述了广东省耕地资源基本状况、耕地资源保护利用的有关政策和法规以及历年来耕地资源保护利用采用的主要措施,并根据耕地保护利用存在问题提出加强耕地资源保护利用的对策.
浅谈油茶在梅州的发展及其栽培管理技术

介绍了油茶产业发展前景及茶油的营养价值和保健作用、梅州油茶发展概况,概述了油茶的栽培管理技术,包括品种、育苗方法、造林、种植、肥水管理、病虫害防治及采收等关键技术.
Distribution of δ~(34S) and δ~(18)O in SO~(2-)_4 in Groundwater from the Ordos Cretaceous Groundwater Basin and Geological Implications

The Ordos Cretaceous Groundwater Basin,located in an arid-semiarid area in northwestern China,is a large-style groundwater basin.SO~(2-)_4 is one of the major harmful components ingroundwater.Dissolved SO~(2-)_4 concentrations,and δ~(34)S-SO~(2-)_4 and δ~(18)SO-SO~(2-)_4 in groundwater from 14 boreholes and in gypsum from aquifer were analyzed.Results show that SO~(2-)_4 in shallow groundwaters originates from precipitation,sulfide oxidation,and dissolution of stratum sulphate,with a big range of δ~(34)S values,from-10.7‰ to 9.2‰,and addition of SO~(2-)_4 in deep groundwater results from dissolution of stratum sulphate,with bigger δ~(34)S values,from 7.8‰ to 18.5‰,compared with those in shallow groundwater.This research also indicates that three types of sulphate are present in the strata,and characterized by high δ~(34)S values and high δ~(18)SO values-style,high δ~(34)S values and middle δ~(18)O values-style,middle δ~(34)S values and low δ~(18)O values-style,respectively.The δ~(34)S-SO~(2-)_4 and δ~(18)O-SO~(2-)_4 in groundwater have a good perspective for application in distinguishing different groundwater systems and determining groundwater circulation and evolution in this area.
Geochemistry of Heavy Oil in the T Block,Oriente Basin and its Origin Mechanism

Exploration and development experience show that there is obvious oil gravity difference between the southern part and northern part of the "Mr'reservoir in the Fanny oil field in the slope of the Oriente Basin,Ecuador.The American Petroleum Institute Gravity (API) values of oils in the northern part are higher than the one in the southern part of the Fanny oil field,with the values of 20° and 10.0°-13.0°,respectively.So the primary purpose of this study was to analyze the heavy oil characteristics of biodegradation and the oil-oil correlation according to the biomarker data and the δ~(13)C signature of oil samples from T block.The results of the hydrocarbon gas chromatography fingermark and the inversion attribute characteristics indicated that there are fluid compartments between the "M1" reservoir of Fanny south.Finally,the models of oil-gas accumulation under the control of multiple-activities of complicated fault systems,as well as the origin of heavy oil,are contended.The early stage oils from the western part of the basin were biodegraded heavily in varying degrees in the whole basin,and the later stage oils were derived from the southern part in a large scale and were mature and lighter.Generally,oil mixing is the primary control of net oil properties,such as API gravity in Oriente Basin.We therefore predicted that the API gravity variation of oil pools radically depends on the injection amount of the later stage oil.Because of the shale barrier in the "Mr'reservoir of Fanny south,the later stage hydrocarbon could not pass through and contribute to increase the oil API value.
选择式和追踪式教学法在断层解剖学教学中的运用

断层解剖学是用断层方法研究和表达人体正常形态结构及其基本功能的科学~([1]),属于解剖学的一个分支.众所周知,教学法是决定教学效果的重要因素.断层解剖学教学的一个误区是让学生一个断层一个断层,一个结构一个结构的逐一"死记硬背".合理运用多种教学方法即可抓住重点又可举一反三,而且对于拓展学生分析和解决临床问题的能力具有重要意义.现将选择式和追踪式教学法介绍如下.
Reproductive toxicity of organic extracts from petrochemical plant effluents discharged to the Yangtze River, China

Water pollution of the Yangtze River in China became one of challenges that the government is facing today. Increasing numbers of petrochemical plants were built along the river in past decades, and numbers of organic chemicals were discharged into the river. Our goal was to establish in vitro system on rat sertoli cells, spermatogenic cells and leydig cells to investigate the reproductive toxicity potential induced by organic extracts from petrochemical effluents. Our results showed that the organic extract depressed the viability (p < 0.01) and destroyed the plasma membrane integrity of sertoli cells and spermatogenic cells to a certain degree. Accordingly, proportion of early apoptotic sertoli cells and late apoptotic spermatogenic cells increased significantly. Although significant morphological changes were not detected for leydig cells, the extract was observed to inhibit their testosterone production (p < 0.01). Sertoli cells and spermatogenic cells appeared to be more sensitive and maybe the main targets of the key toxins. These results suggested that the in vitro system on rat testicular cells may be useful to predicate reproductive toxicity potential of organic extracts from petrochemical effluents. More attention should be paid to the petrochemical effluents, because long-term accumulation of these organic compounds in organisms may cause spermatogenesis malfunction and testosterone reduction.
Laboratory culture of the freshwater benthic gastropod Bellamya aeruginosa (Reeve) and its utility as a test species for sediment toxicity

This study aimed to develop original laboratory culture and sediment toxicity testing protocols for the freshwater gastropod Bellamya aeruginosa (Reeve), a new potential species for sediment toxicity testing. B. aeruginosa was successfully cultured with an effective culture system under proposed laboratory conditions. Optimal ad libitum feeding levels for larvae, juveniles, and adults were 2.0, 6.0, and 16.0 mg fish food/(snail.day), respectively. Mean survival rates of juveniles were higher than 90%. The snails could be sexed at 9 weeks of age, and their generation time is approximately 4 months. Reproduction continued all year around; the mean fecundity was 0.55 newborn/(female.day). The utility of this species for bioassays was evaluated in both 10-day and 28-day case studies with artificial sediments. The 10-day LC_(50) of Cu for larvae was 480 μg/g dry weight (dw), and the lowest observed effects concentration of Cu for survival and growth of larvae was 195 μg/g dw. Survival and growth are reliable indicators of acute toxicity. Larvae accumulated more Cu than adults. B. aeruginosa exhibited a higher sensitivity to Cu exposure than standard test species (Hyalella azteca and Chironomus tentans). The 28-day test of sediment toxicity with adults showed that fecundity was a robust endpoint indicator of reproductive toxicity, and the biochemical endpoints of superoxide dismutase, catalase, and glutathione could be used as sensitive biomarkers for Cu-induced oxidative damage. B. aeruginosa can be therefore recommended as a candidate for the standardization of the freshwater sediment toxicity test protocol.
Autoheated thermophilic aerobic sludge digestion and metal bioleaching in a two-stage reactor system

A two-stage process has been developed for stabilization of sludge and removal of heavy metals from the secondary activated sludge with high rate of energy and time conservation. The first stage of the process involves autoheated thermophilic aerobic digestion at 55-60℃ inoculated with less-acidophilic thermophilic sulfur-oxidizing microorganisms (ATAD). The results show that it is possible to maintain the autoheated conditions (55-60℃) in the ATAD reactor up to 24 hr, leading to reduction of 21% total solids (TS), 27% volatile solids (VS), 27% suspended solids (SS) and 33% volatile suspended solids (VSS) from the sludge. The sludge pH also decreased from 7 to 4.6 due to the activity of less-acidophilic thermophilic microorganisms. In the second stage operation, the digested sludge (pH 4.6, TS 31.6 g/L) from stage one was subjected to bioleaching in a continuous stirred tank reactor, operated at mean hydraulic retention times (HRTs) of 12, 24 and 36 hr at 30℃. An HRT of 24 hr was found to be sufficient for removal of 70% Cu, 70% Mn, 75% Ni, and 80% Zn from the sludge. In all, 39% VSS, 76% Cu, 78.2% Mn, 79.5% Ni and 84.2% Zn were removed from the sludge in both the stages.
Estrogenic activities of two synthetic pyrethroids and their metabolites

Synthetic pyrethroids (SPs) are among the most common pesticides in current use, and so far, several SPs have been assessed for their potential estrogenicities by various methods. Previous studies have shown that the estrogenicities partly come from their metabolites. Although considerable information is available with respect to the metabolism and environmental degradation of SPs, little is known about the estrogenicities of the metabolites. In this study, permethrin (PM) and β-cypermethrin (CP), as well as their metabolites (3-phenoxybenzoic alcohol (PBCOH), 3-phenoxybenzaldehyde (PBCHO) and 3-phenoxybenzoic acid (PBCOOH) were evaluated for their estrogenic activities in the MCF-7 human breast carcinoma cell line. In the MCF-7 cell proliferation assay, PM and CP exhibited significant estrogenic activities at 10~(-7) mol/L, comparable to 17β-estradiol (E2) of 10~(-9) mol/L, with the relative proliferative effect ratios of 55.4% and 56.3%, respectively. The real-time quantitative pelymerase chain reaction (qRT-PCR) results confirmed the estrogenicities of PM and CP with significant alteration of pS2 and ERct mRNA levels observed at 10~(-6) mol/L. For the three major metabolites, PBCOH and PBCOOH exhibited estrogenic activities in all assays, while no significant estrogenic responses was observed for PBCHO compared to the vehicle control. In particular, PBCOH had even slightly stronger estrogenic activity than its parent compounds, indicating that metabolism may be one of the reasons for the estrogenicities of the SPs. Given the widespread use of SPs, the toxicological effects of parent compounds and their metabolites should be taken into consideration in the risk assessment of SPs.
Electrochemical disinfection using the gas diffusion electrode system

A study on the electrochemical disinfection with H_2O_2 generated at the gas diffusion electrode (GDE) from active carbon/poly-tetrafluorcethylene was performed in a non-membrane cell. The effects of Pt load and the pore-forming agent content in GDE, and operating conditions were investigated. The experimental results showed that nearly all bacterial cultures inoculated in the secondary effluent from wastewater treatment plant could be inactivated within 30 min at a current density of 10 mA/cm~2. The disinfection improved with increasing Pt load. Addition of the pore-forming agent NH_4HCO_3 improved the disinfection, while a drop in the pH value resulted in a rapid rise of germicidal efficacy and the disinfection time was shortened with increasing oxygen flow rate. Adsorption was proved to be ineffective in destroying bacteria, while germicidal efficacy increased with current density. The acceleration rate was different, it initially increased with current density. Then decreased, and finally reached a maximum at a current density of 6.7 mA/cm~2. The disinfection also improved with decreasing total bacterial count. The germicidal efficacy in the cathode compartment was approximately the same as in the anode compartment, indicating that the contribution of direct oxidation and the indirect treatment of bacterial cultures by hydroxyl radical was similar to the oxidative indirect effect of the generated H_2O_2.
Organochlorine compounds and polycyclic aromatic hydrocarbons in surface sediment from Baiyangdian Lake, North China: Concentrations, sources profiles and potential risk

Organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs) were determined in nineteen surface sediment samples collected from Baiyangdian Lake and its inflowing fiver (Fuhe River) in North China. Total concentrations of OCPs, PCBs and PAlls in sediments ranged from 5.4 to 707.6 ng/g, 2.3 to 197.8 ng/g, and 101.3 to 6360.5 ng/g, respectively. The levels of contaminants in Fuhe River were significantly higher than those in Baiyandian Lake. For hexachlorocyclohexane (HCHs) and dichlorodiphenytfichloroethanes (DDTs), α-HCH and p,p'-DDT were predominant isomers; while for PCBs, PCB 28/31, PCB 40/103, PCB 60, PCB 101, and PCB 118 were predominant congeners. Possible sources derived from historical usage for OCPs and incomplete combustion fuel, wood, and coal and exhaustion of boats or cars for PAHs. Risk assessment of sediment indicated that sediments in Fuhe River were likely to pose potential biological adverse impact.
完善环境准入制度积极优化经济增长

人类的开发建设活动都会不同程度地产生环境问题,这就要求人类必须从环境的要求来考虑开发建设活动的后果,既考虑开发活动对当代的影响,也要考虑当代的开发活动对后代的影响.建立和完善环境准入制度是开发建设活动合理而可持续的重要保证.
黄浦江水质的模糊数学综合评价研究

在黄浦江的水质综合评价中,采用基于加权平均模型的模糊数学综合评价法进行评价,取得了良好的效果.研究结果表明,黄浦江水质基本属于Ⅲ~Ⅳ类水,偏Ⅳ类.并尝试采用SPSS统计软件进行多元统计分析,深入探讨各污染指标之间的相互关系,更好地了解黄浦江水质的污染特性.通过SPSS统计软件的相关分析结果表明,所选择的7项污染指标是有代表性的.
区域间水环境容量多目标公平分配的水环境基尼系数法

基于区域间水环境容量分配的控制指标和公平性准则分析,应用水环境基尼系数概念,以定量表达各公平性准则;并将各控制指标的水环境基尼系数均达到最小值作为界定多目标公平性的标准值.以此为基础,以各区域水环境容量分配比例为搜索变量,以水环境基尼系数达到多目标公平性标准值为目标,采用多目标最优化方法确定区域间水环境容量公平分配方案.应用该方法,对长乐江流域水环境容量在区域间的分配进行了实例分析.结果表明,将水环境基尼系数作为水环境容量分配结果的公平性衡量指标具有客观性,确定的水环境容量公平分配方案体现了多目标公平性.水环境基尼系数法可以推广至同一层面、具有可比性的排污单位间水环境容量公平分配问题上,且方法简单、可靠.
加味逍遥散颗粒联合手术治疗静脉性勃起功能障碍

目的 探讨加味逍遥散颗粒联合手术治疗静脉性勃起功能障碍.方法 将患者分为两组:单纯静脉性勃起功能障碍手术治疗,为对照组(Ⅰ组);静脉性勃起功能障碍手术后服加味逍遥散颗粒组(Ⅱ组), Ⅱ组患者在手术治疗后第7个月开始服中药加味逍遥散颗粒,1剂/d,3个月为一个疗程;对两组患者于手术后第6、12、18、24个月进行随访.结果 两组患者手术后第6个月,第12个月随访,IIEF5评分差异无统计学意义(P＞0.05); 第18个月和第24个月随访,Ⅱ组疗效明显好于Ⅰ组(P<0.05).两组患者性生活感兴趣度和夫妻舒适感比较,手术后患者服加味逍遥散颗粒后,患者对过性生活更感兴趣,夫妻舒适感也明显提高.结论 治疗静脉性勃起功能障碍,加味逍遥散颗粒联合手术其疗效明显优于单纯手术治疗.
中枢性睡眠呼吸暂停的研究进展

中枢性睡眠呼吸暂停(central sleep apnea,CSA)是以呼吸动力缺乏导致的通气不足和换气障碍为特征.CSA与阻塞性呼吸暂停(obstructive sleep apnea,OSA)的不同之处在于气流停止的同时无呼吸运动.临床上OSA的患者可能也会出现明显的中枢性呼吸暂停的发作,而且以中枢性呼吸暂停开始的患者可能会因为呼吸运动的恢复而变成阻塞性即混合性呼吸暂停.因此,在中枢性和阻塞性呼吸暂停之间有显著的重叠之处.
丹酚酸B对实验性大鼠急性心肌缺血的保护作用

目的 观察注射丹酚酸B对异丙肾上腺素(ISO)诱导的急性心肌缺血大鼠模型的保护作用.方法 采用腹腔注射ISO方法复制大鼠急性心肌缺血模型,观察丹酚酸B对大鼠心电图及心肌组织形态学的影响,检测血清中乳酸脱氢酶(LDH)、肌酸激酶(CK)、超氧化物歧化酶(SOD)和丙二醛(MDA)的含量.结果 丹酚酸B 10、5 mg/kg能有效对抗心电图ST段下移和T波的升高,显著降低血清中LDH、CK和MDA的含量,升高血清中SOD的含量,与模型组比较差异有显著性(P<0.05,P<0.01).结论 丹酚酸B对ISO诱导大鼠急性心肌缺血有较好的保护作用.