mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Accessing Alignments of Ontologies via loT Based on SKOS Data Model

Many ontologies are provided to representing semantic sensors data. However, heterogeneity exists in different sensors which makes some service operators of Internet of Thing (IoT) difficult (such as such as semantic inferring, non-linear inverted index establishing, service composing). There is a great deal of research about sensor ontology alignment dealing with the heterogeneity between the different sensor ontologies, but fewer solutions focus on exploiting syntaxes in a sensor ontology and the pattern of accessing alignments. Our solution infers alignments by extending structural subsumption algorithms to analyze syntaxes in a sensor ontology, and then combines the alignments with the SKOS model to construct the integration sensor ontology, which can be accessed via the IoT. The experiments show that the integration senor ontology in the SKOS model can be utilized via the IoT service, and the accuracy of our prototype, in average, is higher than others over the four real ontologies.
Random Access and Resource Allocation for the Coexistence of NOMA-Based and OMA-Based M2M Communications

In the future fifth generation (5G) systems, non-orthogonal multiple access (NOMA) is a promising technology that can greatly enhance the network capacity compared to orthogonal multiple access (OMA). In this paper, we propose a novel random access (RA) and resource allocation scheme for the coexistence of NOMA-based and OMA-based machine-to-machine (M2M) communications, which aims at improving the number of successful data packet transmissions and guaranteeing the quality of service (QoS) (e.g., the minimum data rate requirement) for M2M communications. The algorithm of joint user equipment (UE) paring and power allocation is proposed for the coexisting RA (i.e., the coexistence of NOMA-based RA and OMA-based RA). The resource allocation for the coexisting RA is investigated, thus improving the number of successful data packet transmissions by more efficiently using the radio resources. Simulation results demonstrate that the proposed RA and resource allocation scheme outperforms the conventional RA in terms of the number of successful data packet transmissions, thus is a promising technology in future M2M communications.
CIP2A及c-myc在结直肠腺癌组织中的表达及其临床意义

目的研究CIP2A及c-myc在结直肠管状腺癌中的表达及与临床病理因素的关系。方法采用RT-PCR法及免疫组织化学法检测2014年10月至2015年12月期间经青海大学附属医院胃肠肿瘤外科治疗的60例结直肠癌患者的腺癌组织和周围正常组织中CIP2A及c-myc的表达水平;观察它们在不同临床病理因素下的表达差异。结果CIP2A和c-myc基因在结直肠腺癌组织中的表达明显高于正常组织(P < 0.05);CIP2A和c-myc基因在不同年龄、性别、瘤体直径以及肿瘤位置的结直肠腺癌患者中的表达差异无统计学意义(P > 0.05);但在有无淋巴结转移及局部浸润和不同临床分期及组织学分类中的表达差异有统计学意义(P< 0.05)。结论联合检测CIP2A及c-myc基因表达对预测结直肠腺癌的临床分期及评价预后具有一定的指导价值。
Therapeutic gene editing: delivery and regulatory perspectives

Gene-editing technology is an emerging therapeutic modality for manipulating the eukaryotic genome by using target-sequence-specific engineered nucleases. Because of the exceptional advantages that gene-editing technology offers in facilitating the accurate correction of sequences in a genome, gene editing-based therapy is being aggressively developed as a next-generation therapeutic approach to treat a wide range of diseases. However, strategies for precise engineering and delivery of gene-editing nucleases, including zinc finger nucleases, transcription activator-like effector nuclease, and CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats-associated nuclease Cas9), present major obstacles to the development of gene-editing therapies, as with other gene-targeting therapeutics. Currently, viral and non-viral vectors are being studied for the delivery of these nucleases into cells in the form of DNA, mRNA, or proteins. Clinical trials are already ongoing, and in vivo studies are actively investigating the applicability of CRISPR/Cas9 techniques. However, the concept of correcting the genome poses major concerns from a regulatory perspective, especially in terms of safety. This review addresses current research trends and delivery strategies for gene editing-based therapeutics in non-clinical and clinical settings and considers the associated regulatory issues.
水系灾害医学应急救援体系的构建

有关统计数据显示,建国以来发生在我国沿海、内陆水系较大船难事件有10次之多。除1963年5月1日在苏岩礁触礁沉没的跃进号货轮外,一次造成罹难人数在100人以上的船难事件就有7次;其中罹难人数最多的达442人,是发生于2015年6月1日的湖北监利长江“东方之星”号事件;最少的达131人,是发生于2006年6月31日的四川合江长江“荣建”号事件。由此可见,水系灾害对人民生命安全与健康危害巨大。随着全球气候持续变暖,厄尔尼诺现象频发导致各种自然灾害,以及其他不可预测的人为灾害事件,这些因素均对加快推进水系灾害医学应急救援体系建设提出了迫切的现实需求。
Generation of reactive atomic species of positive pulsed corona discharges in wetted atmospheric flows of nitrogen and oxygen

The emission spectra of excited radicals (OH (A~2∑), O (3p~5 P), H_a (3P)) and emissive species (N_2~+ (B~2∑_u~+), N_2 (C~3II_u)) produced by positive pulsed high-voltage needle-plane corona discharges in atmospheric N2 and 02 flows wetted with 10% H20 at 80 °C are used to investigate the relative concentrations of the produced radicals. The results indicate that the tendencies of the concentrations of radicals with discharge conditions are similar to each other due to their similar excitation processes by electron collision. The influence of oxygen flow mixed with the nitrogen flow on the emission intensities of O (3p~5P → 3s~5S_2~0), H_a (3P → 2S), N_2~+ (B~2∑_u~+ →X~2∑_g~+ 0-0),and N_2 (C~3II_U → B~3II_g 1-0) is presented. When the flow rate of oxygen addition is varied from 0-30 ml min~(-1),the emission intensities of O (3p~5P → 3s~5S_2~0), H_a (3P → 2s), and N2+ (B~2∑_u~+ → X~2∑_g~+ 0-0) increase and reach a maximum. Then, if the oxygen flow rate increases further, the emission intensities tend to decrease. However, the intensity of N_2 (C~3II_u → B~3II_g 1-0) decreases monotonously with the increasing oxygen flow, which indicates that the electron density decreases with the increasing oxygen flow. By the tendencies of the relative intensities to N_2 (C~3II_u → B~3II_g 1-0), the concentrations of the total produced O,H, and N_2~+ are shown to increase with the oxygen flow. Based on the reactions for the production of H and O without and with the addition of O_2, the analytic solutions for H and O production are derived in accordance with the experimental results.
生态系统红色名录:进展与挑战

世界自然保护联盟(IUCN)在物种受威胁程度评估标准的制订与应用方面具有权威性,其不断更新并发布的全球物种红色名录(http://www.iucnredlist.org/)被广泛采用,作为生物多样性保护的重要参考。经过半个多世纪的努力,物种红色名录项目取得了重要进展,成为IUCN最有影响力的标志性工作。主要体现在三个方面:(1)为目标明确、过程透明且结果可重复的物种生存风险评估建立了定量的评估标准;(2)从仅包括受威胁物种的红色名录扩展到也包括未受威胁物种的不断增长的物种数据库;(3)在不同国家和地区以及不同生物类群中得到广泛应用(Rodriguez et al, 2012)。 IUCN全球物种红色名录己经包括86,313个物种,其中24,307种(28.2%)受到威胁(www.iucnredlist.org/)。据不完全统计,不同国家或区域的不同类群的物种红色名录已经发布了数千个,仅欧洲就有3,500个之多(Rodriguez et al, 2012); 100多个国家发布了至少250个不同类群的国家物种红色名录(Zamin et al,2010)。中国的高等植物和脊椎动物红色名录分别于2013年和2015年由环境保护部和中国科学院正式联合发布(蒋志刚等,2015)。
Chemical characteristics and Pb isotopic compositions of PM_(2.5) in Nanchang, China

In mid-September 2013, PM_(2.5) samples were collected at six sites in Nanchang, Jiangxi Province, China to quantify nine water-soluble ions (Ca~(2+), Mg~(2+), K~+, Na~+, NH_4~+, SO_4~(2-), CI~-,F~-, NO_3~-), 29 trace elements(Ba. Zn, Pb, Ni, Mo, Cr, Cu, Sr, Sb, Rb, Cd, Bi, Zr, V, Ga, Li, Y, Nb, W, Cs, Tl, Sc, Co, U, Hf, In, Re, Be, and Ta) and to characterize Pb isotopic ratios (~(207)Pb/~(206)Pb, ~(208)Pb/~(206)Pb, and ~(207)Pb/~(204)Pb) for identifying the mair source(s)of Pb. The results showed that the average daily PM_(2.5) concentration (53.16 ±24.17) μg/m3 was within the secondary level of the Chinese ambient air quality standard. The combined concentrations ol SO_4~(2-), NH_4~+, and NO_3~-to total measured water-soluble ion concentrations in PM_(2.5) ranged from 79.40% to 95.18%, indicating that anthropogenic sources were significant. Coal combustion and vehicle emissions were both contributors to PM_(2.5) based on the NO_3~-/SO_4~(2-) ratios. Wushu School experienced the lowest concentrations of PM_(2.5) and most trace elements among the six sampling sites. Enrichment factor results showed that Tl, Cr, In, Cu, Zn, Pb, Bi, Ni, Sb, and Cd in PM_(2.5) were affected by anthropogenic activities Cluster analysis suggested that Cd, Sb, Pb, Re, Zn, Bi, Cs, Tl, Ga, and In were possibly related to coal combustion and vehicle exhaust, while Ni, Nb, Cr, and Mo may have originated from metal smelting. Pb isotopic tracing showed that coal dust, cement dust, road dust and construction dust were the majoi Pb sources in PM_(2.5) in Nanchang. Combined, these sources contributed an average of 72.51% of the Pb measured, while vehicle exhaust accounted for 27.49% of Pb based on results from a binary Pb isotope mixed model.
Bonded-particle model calibration using response surface methodology

The bonded-particle model (BPM) is commonly used in numerical analysis of the mechanical behavior of rock samples. Constructing a BPM model requires specification of a number of microstructural parameters, including the parallel-bond tensile strength, parallel-bond cohesion strength, parallel-bond effective modulus, parallel-bond friction angle, and parallel-bond stiffness ratio. These parameters cannot be easily measured in the laboratory or directly related to either measurable or physical material parameters. Hence, a calibration process is required to choose the values to be used in simulations of physical systems. In this study, response surface methodology along with the central composite design approach is used to calibrate BPMs. The sensitivities of the microparameters related to the uniaxial compressive strength(UCS) and elasticity modulus (i.e., the macroscopic responses of the models) are thoroughly scrutinized. Numerical simulations are performed to carefully assess the performance of the model. It is found that the elasticity modulus is highly correlated with the parallel-bond effective modulus. In addition, the parallel-bond tensile and cohesion strengths are the two most significant microparameters with a considerable effect on the UCS. The predicted values determined by the proposed approach are in good agreement with the observed values, which verifies the applicability of the proposed method.
Estimation of Age, Growth and Maturation of Purpleback Flying Squid, Sthenoteuthis oualaniensis, in Bashi Channel, Central Pacific Ocean

The age, growth and maturation of Sthenoteuthis oualaniensis were determined with statolith data collected with a light purse seine from the Bashi Channel of central Pacific Ocean. The estimated longevity of the squid was no more than 6 months for females, and no more than 5 months for males. Growth in mantle length (ML) was best described by logistic models for both females and males, while growth in body weight (BW) was best fitted by power curves. The maximum absolute growth rate (AGR) and instantaneous growth rate (IGR) in ML or BW both occurred at 91–105 days for females and 76–90 days for males. Back calculated hatching dates were from October to January, with a peak in December, although the short duration of sampling date might have had an influence on the result. The lower percentage of mature females (37.2%) suggested that the study area during the sampling date was not a spawning ground for the species. Size and age at first maturity were 183 mm ML and 136 days for females, whereas they were 156 mm ML and 85 days for males.
系统性红斑狼疮合并黑热病一例

早期识别SLE患者合并黑热病是必需的,因为强效免疫抑制剂的使用可以导致黑热病发展成快速进展性疾病,而且黑热病患者若不予抗虫治疗,病死率高达90%以上故及时确诊是关键所在。本篇文章强调了流行病学资料、如何快速作出诊断及及时治疗罕见致死性疾病的重要性,对临床工作者有一定指导意义。因此当血细胞低下不能用原发病及免疫抑制剂的应用解释时,临床医生应考虑到寄生虫感染的可能性。
卡麦角林预防卵巢过度刺激综合征的应用进展

卵巢过度刺激综合征(OHSS)是一种主要发生在辅助生殖技术促排卵时的自限性疾病,没有特异性疗法,但近年国外有越来越多的报道指出卡麦角林对OHSS有显著的预防作用。本文就近年卡麦角林预防OHSS的应用进展进行分析总结,国外对卡麦角林的研究已经比较成熟,卡麦角林对预防OHSS的效果确切,可以降低OHSS发生率和严重性,且妊娠期间使用对胎儿的安全性也令人满意。然而由于国内缺乏卡麦角林在OHSS预防中的报道且该药物适应证尚未包含OHSS,在大量应用前尚待高质量的随机对照研究进行探索。
气相色谱法测定挤塑聚苯乙烯泡沫塑料中3种发泡剂的残留量

目前,挤塑聚苯乙烯泡沫主要作为保温材料和防潮材料运用于墙体、屋面、地面、冷库和道路等地方,常用发泡剂有氢氟氯烃、氢氟烃、烃类、二氧化碳,由于挤塑聚苯乙烯泡沫是内部完全闭孔发泡,发泡剂基本上留在泡孔内。氢氟氯烃释放到环境中会造成臭氧空洞和温室效应,目前主要对海水和空气中氢氟氯烃进行检测。我国自加入蒙特利尔公约后,加快了无氟取代的进程,体现在聚氨酯泡沫和聚苯乙烯泡沫行业的发泡剂替代技术上。在我国现行的标准中未对挤塑聚苯乙烯中残留发泡剂的种类和含量进行分析。测定泡沫中发泡剂的方法有滴定法、热红联用分析法和气相色谱法等。其中滴定法由于挤塑聚苯乙烯泡沫塑料用于保温材料需具备阻燃性,无法完全燃烧,不能准确测定;热红联用法使用的样品量极少,测定结果误差较大;挤塑聚苯乙烯泡沫塑料板可溶于有机溶剂,且有机发泡剂能被气相色谱分离。文献[9-11]研究了气相色谱法在分离发泡剂中的应用,结果表明:气相色谱法具有灵敏度高、分析时间短、选择性高等优点,能够有效测定发泡剂的含量。本工作优化了发泡剂标准曲线的制作方法,建立了测定挤塑聚苯乙烯泡沫塑料中3种发泡剂残留量的气相色谱法。
2007-2016年作者机构分布对《中国应用生理学杂志》的影响

目的:应用作者机构的分布情况,评估中国应用生理学杂志的学术影响力。方法:提取CNKI中《中国应用生理学杂志》2007-2016年刊载论文,选取发文数量最高的10个机构,运用文献计量学方法对其基金资助情况、合作情况、被引及下载情况进行定量分析。结果:《中国应用生理学杂志》2007 -2016年共刊载论文1550篇,发文最多的10个机构,其论文发表量为24.06%,所发论文基金支持率高,机构和作者之间有着高度合作,论文被引率和下载量较大。结论:《中国应用生理学杂志》作者发文机构广泛,论文质量高,在基础医学领域有着较大的影响力。
A New Empirical Method for Constructing Capillary Pressure Curves from Conventional Logs in Low-Permeability Sandstones

Pore structure reflected from capillary pressure curves plays an important role in low-permeability formation evaluation. It is a common way to construct capillary pressure curves by Nuclear Magnetic Resonance (NMR) log. However, the method's efficiency will be severely affected if there is no NMR log data or it cannot reflect pore structure well. Therefore, on the basis of J function and diagenetic facies classification, a new empirical model for constructing capillary pressure curves from conventional logs is proposed here as a solution to the problem. This model includes porosity and the relative value of natural gamma rays as independent variables and the saturation of mercury injection as a dependent variable. According to the 51 core experimental data sets of three diagenetic facies from the bottom of the Upper Triassic in the western Ordos Basin, China, the model's parameters in each diagenetic facies are calibrated. Both self-checking and extrapolation tests show a positive effect, which demonstrates the high reliability of the proposed capillary pressure curve construction model. Based on the constructed capillary pressure curves, NMR T_2 spectra under fully brine-saturated conditions are mapped by a piecewise power function. A field study is then presented. Agreement can be seen between the mapped NMR T_2 spectra and the MRIL-P log data in the location of the major peak, right boundary, distribution characteristics and T_2 logarithmic mean value. In addition, the capillary pressure curve construction model proposed in this paper is not affected by special log data or formation condition. It is of great importance in evaluating pore structure, predicting oil production and identifying oil layers through NMR log data in low-permeability sandstones.
Arsenic, Iron and Organic Matter in Quaternary Aquifer Sediments from Western Hetao Basin, Inner Mongolia

To investigate geochemical and mineralogical features of sediments from aquifers containing high levels of dissolved arsenic (As) in western Hetao Basin, Inner Mongolia, sediment samples were collected for XRD (X-ray diffraction), amorphous Fe/Mn oxides, and humic/fulvic acid analyses, in addition to As determination. In the study area, the total As contents in the sediments were in the range 5.3–28.8 mg/kg; while that associated with humic substances in the range 4–9 mg/kg, accounting for 26%–47% of the total As. The results of XRD analysis suggest that clay and silt contain certain small amounts of iron oxides minerals, such as ferrihydrite, hematite and goethite, whereas have higher As and Fe_2O_3 contents. Up to one third of As in the sediments could be extracted by ammonium oxalate, and high As contents were generally found in organic-rich clay or silty clay samples with high FA/HA ratio. As is strongly associated with humic substances and Fe oxyhydroxides, which may be the major sink and source of As in the aquifer sediments.
Thermal analysis of walls in a new-type billet caster tundish with a vacuum shell

To reduce thermal loss from molten steel in a tundish during continuous casting production, a new tundish fabricated by welding radiation-proof steel plates onto the steel plates of the exterior walls of a billet caster tundish was proposed. This new tundish was used to investigate the effect of pressures inside the vacuum chamber on the uniformity of the temperature of molten steel and the thermal conditions of the vacuum layer. The results show that the conversion radiation coefficient is not sensitive to pressure and its value at high temperatures is merely 1.5 times greater than that at low temperatures. Pressure is the key factor affecting additional factor of conversion convection. This factor is more than 100 times greater at 10~5 Pa than at 10~2 Pa, and the temperature at inner points at 10~2 Pa is, on average, 4 K higher than that at 10~5 Pa. Meanwhile, the local temperature difference of the inlet at 10~2 Pa is 1 K higher than that at 10~5 Pa. Thus, the proposed vacuum billet caster tundish can achieve low superheat teeming of steel because of the thermal preservation capability of the vacuum, which helps to reduce the tapping temperature and improve the uniformity of the temperature of steel.
Cloning and expression of three thaumatin-like protein genes from Polyporus umbellatus

Genes encoding thaumatin-like protein (TLPs) are frequently found in fungal genomes. However, information on TLP genes in Polyporus umbellatus is still limited. In this study, three TLP genes were cloned from P. umbellatus. The full-length coding sequence of PuTLP 1, PuTLP2 and PuTLP3 were 768, 759 and 561 bp long, respectively, encoding for 256,253 and 187 amino acids. Phylogenetic trees showed that P. umbellatus PuTLP1, PuTLP 2 and PuTLP3 were clustered with sequences from Gloeophyllum trabeum, Trametes versicolor and Stereum hirsutum, respectively. The expression patterns of the three TLP genes were higher in P. umbellatus with Armillaria mellea infection than in the sclerotia without A. mellea. Furthermore, over-expression of three PuTLPs were carried out in Escherichia coli BL21 (DE3) strain, and high quality proteins were obtained using Ni-NTA resin that can be used for preparation of specific antibodies. These results suggest that PuTLP1, PuTLP2 and PuTLP3 in P. umbellatus may be involved in the defense response to A. mellea infections.
Establishment of a new acute-on-chronic liver failure model

To establish an animal model of acute-on-chronic liver failure (ACLF) that would replicate the pathological process of ACLF in humans, rats were administered porcine serum (PS) for 11 weeks. Liver fibrosis was determined by pathological and biochemical assessments. The animals then were injected with D-galactosamine (D-gal) and lipopolysaccharide (LPS). The survival times of animals with cirrhosis and ACLF were determined over 48 h. Other animals were killed at 0,4,8 and 12 h after administration of D-gal/ LPS. Liver injury was assessed by histopathological analysis and biochemical indices, and apoptosis was detected by Western blot and TUNEL analysis. After PS administration for 11 weeks the serum levels of hyaluronic acid and N-procollagen type III peptide increased significantly, and serious fibrosis and cirrhosis was observed at weeks 10 and 11. Cirrhotic rats were injected with D-gal/LPS to induced ACLF; the rate of mortality over 48 h was 80%. ALT and AST levels increased markedly at 4 h, but decreased significantly at 8 and 12 h post-treatment. The total bilirubin, direct bilirubin, and total bile acids levels increased markedly at 8 and 12 h. Clotting times, TNF-a and IL-6 levels increased significantly, except for 12 h post-treatment. Apoptosis, inflammation and necrosis were elevated as determined by hematoxylin-eosin staining and TUNEL assays. BCL-2 levels decreased significantly, While BAX levels increased significantly. Cytochrome c expression peaked at 8 h post-D-gal/LPS treatment. In conclusion, an ACLF model induced by PS and D-gal/LPS was established and the underlying mechanisms of ACLF development were explored.
A Special MJO Event with a Double Kelvin Wave Structure

The second Madden–Julian Oscillation (MJO) event during the field campaign of the Dynamics of the MJO/Cooperative Indian Ocean Experiment on Intraseasonal Variability in the Year 2011 (DYNAMO/CINDY2011) exhibi ted an unusual double rainband structure. Using a wavenumber-frequency spectral filtering method, we unveil that this double rainband structure arises primarily from the Kelvin wave component. The zonal phase speed of the double rainbands is about 7.9 degree per day in the equatorial Indian Ocean, being in the range of convectively coupled Kelvin wave phase speeds. The convection and circulation anomalies associated with the Kelvin wave component are characterized by two anomalous convective cells, with low-level westerly (easterly) and high (low) pressure anomalies to the west (east) of the convective centers, and opposite wind and pressure anomalies in the upper troposphere. Such a zonal wind–pressure phase relationship is consistent with the equatorial free-wave dynamics. While the freeatmospheric circulation was dominated by the first baroclinic mode vertical structure, moisture and vertical motion in the boundary layer led the convection. The convection and circulation structures derived based on the conventional MJO filter show a different characteristic. For example, the phase speed is slower (about 5.9 degree per day), and there were no double convective branches. This suggests that MJO generally involves multi-scales and it is incomplete to extract its signals by using the conventional filtering technique.
Observation of Wind Shear during Evening Transition and an Estimation of Submicron Aerosol Concentrations in Beijing Using a Doppler Wind Lidar

The wind speed and direction measured over six months by a Doppler wind lidar (Windcube-8) were compared with wind cup anemometers mounted on the 325-m Beijing meteorological tower (BMT). Five mountain–plain wind cases characterized by wind direction shear were selected based on the high-frequency (1.1 s) wind profile of the Windcube-8 and analyzed with 1-h mesoscale surface weather charts. Also analyzed was the relationship between insitu PM_1 (aerodynamic diameter ≤ 1 μm) concentrations measured at 260 m on BMT and the carrier-to-noise ratio (CNR) of the co-located Windcube-8. The results showed that the 10-min averaged wind speed and direction were highly correlated (R = 0.96–0.99) at three matched levels (80, 140, and 200 m). The evening transition duration was 1–3 h, with an average wind speed of 1 m s~(-1) at 80 m above the ground. In addition, there was a zero horizontalwind-speed zone along the wind direction shear line, and in one case, the wind speed was characterized by a Kelvin–Helmholtz gravity wave. The variability of the PM_1 concentrations was captured by the CNR of the Windcube-8 in a fair weather period without the long-range transport of dust.