mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Reserves of Natural Gas Hydrates Equivalent to 100-150 Billion m~3 Natural Gas Has Been Discovered in the Pearl Mouth Basin of the South China Sea

Scientists have suggested that combustible ice in global marginal seas, deep trough areas and ocean basins covers an area of 400 million km~2, and its total reserve is twice the amount of the global proven oil, coal and gas reserves, equivalent to 50 times the amount of conventional natural gas reserves. Only this global submarine combustible ice resource could be available for human use within 1000 years. China Geological Survey (CGS) has conducted integrated geological investigations of natural gas hydrates in the Pearl River Mouth basin of Guangdong Province through time, and has completed 40 geological survey voyages, 45,800 km~2 of highresolution multi-channel seismic surveys, 36,800 km of multi-beam measurements, 7,100 km of shallow stratigraphic section measurements, 1,480 stations for sampling submarine geological samples and 222 stations for submarine heat-flow measurements.
Protective Effect of Mulberry Extract against Pb-induced Learning and Memory Deficits in Mice

Lead (Pb) is ubiquitous in the environment, and low-level Pb exposure can cause neurotoxicity and irreversible damage to children's cognition, learning and memory ability. Nutritional intervention is an effective method to prevent Pb poisoning. Mulberry is rich in anthocyanins, possessing protective effects for nerves. This study investigated the neuroprotective effects of mulberry extract (ME) against Pb-induced learning and memory deficits in mice. The results showed that the learning and memory abilities of mice, assessed using the Morris test, improved significantly after treatment with ME at a dose of 100 mg/kg body weight. The level of Pb in the brains of mice in the three ME intervention groups decreased significantly, while NO production and anti-oxidant enzymes were significantly restored. It is suggested that ME inhibits Pb-induced neurotoxicity by reversing Pb-induced alterations in the aspect of neurotoxic effects and improving learning and memory.
Epidemic of Rabies and Effect of Its Vaccine against a Dog That Consecutively Attacked Ten People in One Day

On December 21, 2010, a stray dog consecutively attacked 10 people in Lengshui Village, Ningyuan County, Yongzhou City, Hunan Province, China. The dog was killed by the local CDC staff and vicinity villager, its brain tissue sample was taken within 24 h. The epidemic focus was disinfected and the injured people received post exposure prophylaxis (PEP). Pathogens were detected in the tissue sample by the provincial CDC. The immunity and safety of rabies vaccine were assayed after PEP, the injured people were regularly followed up in the following 2 y and 6 mon.
Total mesoesophageal esophagectomy

Surgical resection remains the standard treatment for potentially resectable esophageal carcinoma, despite recent advances in multidisciplinary approaches (e.g., radiotherapy and chemotherapy). Postoperative outcomes for patients with esophageal carcinoma are determined by the extent of the primary tumor and the lymphatic spread of the disease. Lymph node status is a particularly strong predictor of survival and recurrent disease.J Some patients can be cured by removal of the regional disease with lymph node metastases, and removal of all potentially involved regional lymph nodes is essential to achieve cure in these patients.
Current practice of gastric cancer treatment

Objective The aim of this review was to overview the current practice of gastric cancer treatment including surgery and other adjuvant modalities. Data sources The review was based on data obtained from the published articles and main guidelines in the East and West. Study selection Articles with high level of evidence or current best evidence in each issue were selected to be reviewed. Results Although varied adjuvant modalities have been proved to be benefit for treating gastric cancer, surgery is still the most important treatment strategy against gastric cancer. Actively adapting to new technology is important but it should be balanced with an effort to establish sound scientific rationale that adheres to oncologic principles. Conclusions Future treatment of gastric cancer will be focused on tailored, personalized therapy. For achieving it, collaboration across disciplines is essential. Also the philosophy of caring for the patients with gastric cancer should be rooted in the realization of true patient benefit regardless of who is providing the care. With these philosophies, we can shift the scientific and technological advances toward triumph over gastric cancer.
Effect of GMA Polymer Compatibilizers on Highly Filled Composites of Low Density Polyethylene/Magnesium Hydroxide

Functional polymers such as polyethylene grafted glycidyl methacrylate (PE-g-GMA) and ethylene-methyl acrylate-glycidyl methacrylate terpolymer (E/MA/GMA) were used as compatibilizers in the preparation of highly filled composites of polyethylene/magnesium hydroxide(PE/MH). Comparative studies were performed on the effect of magnesium hydroxide and stearic acid on the interface within polymer and magnesium hydroxide composites. The effect of polymeric compatibilizers on the properties of the composites was studied using tensile and impact tests, torque rheological analysis, differential scanning calorimetry and environmental scanning electron microscopy (ESEM). The microstructure of highly filled PE/MH composites changed after the addition of functional polymers. The mechanical properties of the composite material increased after compatibilization. The compatibilization processes of PE-g-GMA and E/MA/GMA were different. The grafted polymer was more compatible with polyethylene, which led to a polar polymer phase. In contrast, the tercopolymer tended to adhere to the surface of MH particles.
Interference of the East AsianWinter Monsoon in the Impact of ENSO on the East Asian Summer Monsoon in Decaying Phases

The variability of the East Asian winter monsoon (EAWM) can be divided into an ENSO-related part (EAWM_(EN)) and an ENSO-unrelated part (EAWM_(res)). The influence of EAWM_(res) on the ENSO-East Asian summer monsoon (EASM) relationship in the decaying stages of ENSO is investigated in the present study. To achieve this, ENSO is divided into four groups based on the EAWM_(res): (1) weak EAWM_(res)-El Nino (WEAWM_(res)-EN); (2) strong EAWM_(res)-El Nino (SEAWM_(res)- EN); (3) weak EAWM_(res)-La Nina (WEAWM_(res)-LN); (4) strong EAWM_(res)-La Nina (SEAWM_(res)-LN). Composite results demonstrate that the EAWM_(res) may enhance the atmospheric responses over East Asia to ENSO for WEAWM_(res)-EN and SEAWM_(res)-LN. The corresponding low-level anticyclonic (cyclonic) anomalies over the western North Pacific (WNP) associated with El Nino (La Nina) tend to be strong. Importantly, this feature may persist into the following summer, causing abundant rainfall in northern China for WEAWM_(res)-EN cases and in southwestern China for SEAWM_(res)-LN cases. In contrast, for the SEAWM_(res)-EN and WEAWM_(res)-LN groups, the EAWM_(res) tends to weaken the atmospheric circulation anomalies associated with El Nino or La Nina. In these cases, the anomalous WNP anticyclone or cyclone tend to be reduced and confined to lower latitudes, which results in deficient summer rainfall in northern China for SEAWM_(res)-EN and in southwestern China for WEAWM_(res)-LN. Further study suggests that anomalous EAWM_(res) may have an effect on the extra-tropical sea surface temperature anomaly, which persists into the ensuing summer and may interfere with the influences of ENSO.
离子渗氮热处理技术及设备发展历程与展望

20世纪30年代初,德国B Berghaus 和J Egan 先后提出在气体放电中进行渗氮的方案,在当时的条件下,应用此方案进行了渗氮处理,B Berghaus 在1930年1月16日取得了第一个离子渗氮德国发明专利( No: 375235) ,图1是世界上第一台离子渗氮装置。
GENERALIZED FRACTIONAL TRACE VARIATIONAL IDENTITY AND A NEW FRACTIONAL INTEGRABLE COUPLINGS OF SOLITON HIERARCHY

Based on fractional isospectral problems and general bilinear forms, the generalized fractional trace identity is presented. Then, a new explicit Lie algebra is introduced for which the new fractional integrable couplings of a fractional soliton hierarchy are derived from a fractional zero-curvature equation. Finally, we obtain the fractional Hamiltonian structures of the fractional integrable couplings of the soliton hierarchy.
Male attacks on infants and infant death during male takeovers in wild white-headed langurs (Trachypithecus leucocephalus)

Infanticide was first observed in langurs nearly 50 years ago, and this rare phenomenon has been inferred to have either an evolutionarily adaptive function or to be a pathological and non-functional behavior. In this study, we report 5 male takeover events in one-male groups of white-headed langurs in the Nongguan Karst Hills, Guangxi,China from 1998 to 2006. We recorded 13 attacks on 9 infants by extra-group males or new resident males. During the male takeovers, all of the infants younger than 6 months (with an average age of 3.6 months [N = 11]) in the groups disappeared. The infant death rate during the 4.2 months after takeover by a new male was significantly higher than the infant death rate calculated for most of the year. Older infants that were still nursing (with an average age of 14.1 months [N = 7]) were often attacked and seriously wounded by the extra-group males or new resident males, but all of them survived. The interbirth intervals of females whose infants were assumed to be killed by males were significantly reduced relative to those of females in groups with stable male tenure (mean = 10 months vs 25 months). Our data suggest that males kill unrelated and unweaned infants during the takeover period to decrease the time until the infants' mothers resume fertility. Thus, infanticide would support sexual selection theory in white-headed langurs. The data also show that infanticidal behavior was directed toward the infants, especially those who were still nursing. Female dispersal may function as a counter-strategy to avoid infanticide.
临床药师在消化系统疾病治疗中实施药学服务的体会

解放军第175医院是一所三级甲等医院,作者作为专职临床药师,在消化内科开展临床药学工作,参与消化系统疾病临床药物治疗,并实施全程化药学服务。现将有关工作实践与体会总结如下。
糖皮质激素在儿童支原体肺炎治疗中的疗效分析

支原体肺炎(mycoplasma pneumoniae pneumonia, MPP)是学龄期儿童及青年的一种常见肺炎,婴幼儿亦不少见。主要由肺炎支原体(mycoplasma pneumoniae,MP)感染引起,MP是介于细菌和病毒之间的可以独立存在的最小微生物。近年支原体感染有上升趋势,是引起儿童咳嗽、发热的常见病原体。本研究在阿奇霉素、红霉素序贯治疗,雾化吸入等支原体感染常规治疗的基础上,给予糖皮质激素辅助治疗,取得明显的临床疗效,现报道如下。
Trends of Yield and Soil Fertility in a Long-Term Wheat-Maize System

The sustainability of the wheat-maize rotation is important to China’s food security. Intensive cropping without recycling crop residues or other organic inputs results in the loss of soil organic matter (SOM) and nutrients, and is assumed to be non-sustainable. We evaluated the effects of nine different treatments on yields, nitrogen use efifciency, P and K balances, and soil fertility in a wheat-maize rotation system (1991-2010) on silt clay loam in Shaanxi, China. The treatments involved the application ofrecommended dose of nitrogen (N), nitrogen and phosphorus (NP), nitrogen and potassium (NK), phosphorus and potassium (PK), combined NPK, wheat or maize straw (S) with NPK (SNPK), or dairy manure (M) with NPK (M1NPK and M2NPK), along with an un-treated control treatment (CK). The mean yields of wheat and maize ranged from 992 and 2 235 kg ha-1 under CK to 5962 and 6894 kg ha-1 under M2NPK treatment, respectively. Treatments in which either N or P was omitted (N, NK and PK) gave signiifcantly lower crop yields than those in which both were applied. The crop yields obtained under NP, NPK and SNPK treatments were statistically identical, as were those obtained under SNPK and MNPK. However, M2NPK gave a signiifcant higher wheat yield than NP, and MNPK gave signiifcant higher maize yield than both NP and NPK. Wheat yields increased signiifcantly (by 86 to 155 kg ha-1 yr-1) in treatments where NP was applied, but maize yields did not. In general, the nitrogen use efifciency of wheat was the highest under the NP and NPK treatments; for maize, it was the highest under MNPK treatment. The P balance was highly positive under MNPK treatment, increasing by 136 to 213 kg ha-1 annually. While the K balance was negative in most treatments, ranging from 31 to 217 kg ha-1 yr-1, levels of soil available K remained unchanged or increased over the 20 yr. SOM levels increased signiifcantly in all treatments. Overall, the results indicated that combinations of organic manure and inorganic nitrogen, or returning straw with NP is likely to improve soil fertility, increasing the yields achievable with wheat-maize system in a way which is environmentally and agronomically beneifcial on the tested soil.
Accumulation of Carbohydrate and Regulation of 14-3-3 Protein on Sucrose Phosphate Synthase (SPS) Activity in Two Tomato Species

To explore the differences of carbohydrate metabolism in two tomato species and discuss the possible regulation of 14-3-3 proteins on the sucrose phosphate synthase (SPS) activity, we determined the contents of soluble sugar and starch through high performance liquid chromatography (HPLC). The activities of sugar-metabolizing enzymes were assayed in desalted extract, and the relative expression levels of related genes in sugar metabolism were determined though real-time RT-PCR. The results indicated that glucose and fructose were mainly accumulated during the maturation of the fruit because of the high acid invertase (AI) and neutral invertase (NI) in Micro-Tom (Solanum lycopersicum) fruit, while inSolanum chmielewskii fruit, SPS which went along with the change of sucrose content led to the rapid sucrose increase during the fruit ripening. TFT1 and TFT10, belonging to 14-3-3 protein in tomato, were likely to down-regulated SPS activity during young and intumescence period.
新疆阿希金矿含砷难处理金精矿两段焙烧工艺

研究新疆阿希金矿含砷复杂金精矿的焙烧-浸出过程。结果表明，两段焙烧能有效脱硫脱砷，大幅提升金的浸出率。第一段在550℃弱氧化气氛下焙烧1 h，第二段在600℃氧化气氛下焙烧1 h，焙砂采用稀硫酸浸出，浸出时间2 h，控制终点pH值1.0~1.5，酸浸渣细磨至-38μm约占90%，氰化钠用量为6 kg/t-酸浸渣，氰化浸出48 h，金浸出率达到92.94%。
浸润线地质雷达探测技术在某尾矿坝稳定性分析中的应用

采用地质雷达技术探测江西某矿山尾矿库中浸润线的位置。首先优化得到地质雷达现场探测频率范围35~73 MHz、采样时窗范围0.54~1.13μs、雷达波的采样率范围210~438 MHz及雷达天线最大移动速度1.3 m/s。采用高通滤波及高斯增益控制技术对雷达反射波进行后处理，得到清晰的浸润线反射波形图，浸润线位置的探测结果与观测井测试数据吻合较好。采用四种极限平衡法分析现阶段及尾砂全饱和时尾矿库的稳定性，结果表明现阶段尾矿坝的安全系数均大于2.5，尾砂全饱和时尾矿坝的安全系数均大于1.2，说明该矿山尾矿库能够安全运行。
钇掺杂钽丝拉拔断裂机理分析

研究钇掺杂钽丝退火工艺，采用化学杂质含量分析、微观金相组织及高温气相氧化后表面质量分析，得出不同退火工艺参数下钇掺杂钽丝在拉拔时发生断裂的机理，通过优化、控制退火工艺，改善掺杂钽丝拉拔断裂的质量缺陷，降低拉拔断裂几率。
Impacts of grazing and mowing on reproductive behaviors of Stipa grandis and Stipa krylovii in a semi-arid area

Disturbance can affect biomass allocation of plants, but can it influence plant reproductive behavior? To address this issue, we performed field plant community investigations and explored the reproductive behaviors of Stipa grandis and Stipa krylovii in response to grazing and mowing treatments at Maodeng pasture of Xilinguole League of Inner Mongolia, China during 2007-2009. The results showed that, with a similar niche width for the two plant species under mowing and grazing treatments, mowing significantly increased the ratio of ramet to genet number of S. krylovii and the carbon to nitrogen ratio of S. grandis, and grazing significantly decreased the ratio of vegetative to reproductive tiller biomass of S. grandis and increased the ratio of vegetative to reproductive tiller number of S. krylovii. Regression analysis showed that the significantly positive effect of root to shoot biomass ratio was stronger on the ratio of vegetative to reproductive tiller number of S. grandis than on that of S. krylovii. These results indicated that grazing and mowing influenced the reproductive manner and the process of sexual reproduc-tion of S. grandis and S. krylovii.
Mapping aboveground biomass by integrating geospatial and forest inventory data through a k-nearest neighbor strategy in North Central Mexico

As climate change negotiations progress, monitoring biomass and carbon stocks is becoming an im-portant part of the current forest research. Therefore, national governments are interested in developing for-est-monitoring strategies using geospatial technology. Among statistical methods for mapping biomass, there is a nonparametric approach called k-nearest neighbor (kNN). We compared four variations of distance metrics of the kNN for the spatially-explicit estimation of aboveground biomass in a portion of the Mexican north border of the intertropical zone. Satellite derived, climatic, and topographic predictor variables were combined with the Mexican National Forest Inventory (NFI) data to accomplish the purpose. Performance of distance metrics applied into the kNN algorithm was evaluated using a cross validation leave-one-out technique. The results indicate that the Most Similar Neighbor (MSN) approach maximizes the correlation between predictor and response variables (r=0.9). Our results are in agreement with those reported in the literature. These findings confirm the predictive potential of the MSN approach for mapping forest variables at pixel level under the policy of Reducing Emission from Deforestation and Forest Degradation (REDD+).
Modeling the contribution of abiotic exchange to CO_2 flux in alkaline soils of arid areas

Recent studies on alkaline soils of arid areas suggest a possible contribution of abiotic exchange to soil CO_2 flux (F_c). However, both the overall contribution of abiotic CO_2 exchange and its drivers remain unknown. Here we analyzed the environmental variables suggested as possible drivers by previous studies and constructed a function of these variables to model the contribution of abiotic exchange to Fc in alkaline soils of arid areas. An automated flux system was employed to measure Fc in the Manas River Basin of Xinjiang Uygur autonomous region, China. Soil pH, soil temperature at 0-5 cm (T_s), soil volumetric water content at 0-5 cm (θ_s) and air temperature at 10 cm above the soil surface (T_(as)) were simultaneously analyzed. Results highlight reduced sensitivity of F_c to T_s and good prediction of F_c by the model F_c=R_(10)Q)(10)~((Tas-10)/10)+r_7q_7~((pH-7))+λT_(as)+μθ_s+e which represents F_c as a sum of biotic and abiotic components. This presents an approximate method to quantify the contribution of soil abiotic CO_2 exchange to F_c in alkaline soils of arid areas.
IPCC第五次评估报告对古气候的新认识

认识历史时期的气候变化规律是理解现在气候变化以及预估未来气候变化的基础。随着20世纪以来人类活动对气候变化的影响不断增强，古气候研究所提供的长时间尺度上由自然变化驱动的气候变率信息对准确认识现代气候变化更为重要。代用资料是古气候研究的重要手段，包括岩石、沉积物、冰芯、树轮、珊瑚、贝壳或微化石等。通过对代用资料的分析可以推断不同气候区在历史时期的气候波动和气候系统变化。随着大气物理学理论的不断发展、古气候学研究方法的不断改进及代用资料的不断更新和完善,人类对历史气候变化的了解也在日益深入。气候模式的发展及其在古气候模拟中的应用更促进了人类对气候变化机理的认识。对古气候研究进展的评估一直是IPCC报告的重要内容之一。对比历次IPCC评估报告在古气候方面的评估结论就可以清晰地看出这门学科随着时间的不断发展。
IPCC第五次评估报告反映的大气和地表的观测变化

对气候变化事实的观测是气候变化科学研究的基础，也是IPCC第五次评估报告(AR5)~①的核心内容之一。AR5明确指出，自1750年以来，人类活动使得大气中二氧化碳、甲烷和氧化亚氮等温室气体的浓度增加。最近连续的3个10年比1850年以来其他的任何一个10年都要暖。对于地面观测资料覆盖较全的最长观测时期（1901-2012年），全球几乎所有地区都经历了地表增暖，同时，北半球中纬度陆地区域平均降水量已增加。1950年以来，全球尺度上冷昼和冷夜频数减少，而暖昼和暖夜频数增多，有更多陆地区域的强降水日数可能增加。这些关键评估结论的得出受益于观测资料的日益丰富、 观测研究的不断深入和对气候变化不确定性认识的提高。以下谈谈对AR5中有关大气和地表的气候变化评估内容和成果的理解。
开封市健康人群大肠埃希菌耐药性变迁及多重耐药分析

目的:对开封市健康人群大肠埃希菌的耐药性变迁及多重耐药进行调查。方法对本市自2003~2012年健康从业人员体检分离菌株用K-B法药敏试验结果进行分析。结果健康人群对5种抗菌药物的耐药率10年间呈上升趋势,对4种抗菌药物的耐药率相对稳定;3种抗菌药物的耐药率呈下降趋势,亚胺培南未发现耐药菌株,氨苄青霉素维持95%以上的高耐药率,多重耐药率达39.9%。结论本组资料对大肠埃希菌感染的经验治疗有重要参考价值。
肝脏原发性神经内分泌癌脑转移治疗方式的选择

肝脏原发性神经内分泌癌（primary hepatic neuroendocrine carcinoma，PHNEC )临床少见。我院收治1例晩期PHNEC合并脑转移患者,应用放射治疗取得了理想效果,现报告如下。
FICE染色内镜联合EpCAM检测对肠化型Barrett的诊断价值

近年来,Barrett食管(BE)发病率逐年升高,容易引发食管下段腺癌。在BE患者中,癌变率最高的病理类型为含杯状细胞的特殊肠化型BE,而临床上采用的胃镜检查结合活检诊断BE具有较大的局限性,容易导致误诊或漏诊。本文拟对反流性食管炎患者采用FICE染色内镜联合EpCAM检测与FICE染色内镜联合CK7检查,旨在对比两组的诊断效果。
腮腺区癌肉瘤1例

癌肉瘤是一种恶性程度高、发病率低、好发于老年人的恶性肿瘤。其组织学成分包括癌与肉瘤,两种成分混合生长,因此称其癌肉瘤。由于发生于头颈部涎腺癌肉瘤十分罕见,其发病原因、组织学来源以及病变分级和有效的治疗方法尚不明确。本文拟探讨癌肉瘤的病理特点。
西安市老年人心理需要状况调查与分析

目的调查与分析西安市老年人心理需要状况。方法采用问卷调查法、访谈法以及文献资料法,对西安市老年人的心理需要状况进行调查访问。结果城市老年群体的心理需要包括对精神慰藉的需要、对社会价值的追求、对文化娱乐的需要三个方面,而年龄、性别和婚姻状况是影响心理需要的三个关键维度。结论实施创新型家庭养老模式,加强科学文化教育,完善老年群体组织是满足老年人心理需要的有效途径。
苏州市城区老年人日常生活能力调查

目的了解苏州市老年人日常生活能力,为卫生改革和卫生资源配置提供参考依据。方法采用分层整群随机抽样方法对在苏州市抽取的8个社区共4 635名老年居民进行日常生活能力问卷调查。结果苏州市老年人日常生活能力损害率为11.4%,男性为9.4%,女性为13.0%,ADL损害率随年龄增长有上升趋势;躯体生活自理能力中,损害率最高为"剪脚趾甲"(9.5%);工具性日常生活能力损害率最高为"购物"(13.4%);慢性病患者日常生活能力损害率(12.4%)高于未患病者(9.1%),且随慢性病数目的增加,损害率呈上升趋势。结论日常生活能力是反映老年人健康状况的重要指标,应针对损害率较高的项目进行功能训练,加强高龄、女性及患慢性病人群的健康教育和医疗保健。
辛伐他汀对高同型半胱氨酸血症模型大鼠急性心肌梗死再灌注后血清ET-1、AngⅠ、AngⅡ、CRP、MPO水平的影响

目的探讨辛伐他汀对高同型半胱氨酸血症(Hhcy)大鼠急性心肌梗死(AMI)再灌注后血清内皮素-1(ET)-1、血管紧张素(Ang)Ⅰ、AngⅡ、超敏C反应蛋白(CRP)及髓过氧化物酶(MPO)的影响机制。方法SD大鼠随机划分空白对照组、正常对照组、Hhcy模型组和辛伐他汀干预组,采用腹腔注射同型半胱氨酸(Hcy)诱导Hhcy大鼠,灌胃辛伐他汀制造辛伐他汀干预组,结扎左前降支复制AMI模型。双抗夹心ELISA法检测各组HCY、ET-1、AngⅠ、AngⅡ、CRP、MPO水平。结果①成功建立Hhcy及缺血再灌注大鼠模型。②心肌缺血再灌注前后心电图明显变化。③正常对照组ET-1、AngⅠ、AngⅡ、CRP、MPO等因子产生和释放较空白对照组明显增加(P<0.01)。④模型组ET-1、AngⅠ、AngⅡ、CRP、MPO等因子产生和释放较正常对照组明显增加(P<0.01)。⑤干预组ET-1、AngⅠ、AngⅡ、CRP、MPO等因子产生和释放较模型组明显下降(P<0.01)。结论①心肌细胞缺血再灌注可引起血清ET-1、AngⅠ、AngⅡ、CRP、MPO等血管活性因子的产生和释放增加。②Hhcy可促进心肌细胞缺血再灌注时上述因子的产生和释放。③辛伐他汀虽不能降低血清Hcy浓度,但可有效减少上述因子的产生,从而减少缺血再灌注后心肌损伤,其机制可能与其降低此类血管活性因子导致的炎症反应、氧化应激、血管舒缩功能障碍、凝血抗凝系统失衡等有关。
改良经皮椎体成形术在老年骨质疏松性椎体压缩骨折中的应用价值

目的探讨改良经皮椎体成形术治疗老年骨质疏松性椎体压缩骨折的疗效及其临床应用价值。方法选取2011年1月至2013年4月已被收治的符合标准的56例老年骨质疏松性椎体压缩骨折患者,按知情同意原则随机分为改良组和常规组,各28例。改良组接受改良经皮椎体成形术治疗,常规组接受常规经皮椎体形成术治疗。分析两组患者手术时间、X线透视次数、视觉模拟疼痛评分(VAS)等指标。结果改良组手术时间、术中X线透视次数均低于常规组(均P<0.05),两组患者的VAS评分无统计学差异(P>0.05)。两组患者均未发生骨水泥渗透及脊髓神经损伤等并发症。结论改良经皮椎体成形术在治疗老年骨质疏松性椎体骨折患者时可缩短手术时间、减少术中X线透视次数和医患双方的辐射暴露危害,降低影像监测费用和手术风险,可在临床上推广使用。
乳腺小黏蛋白基因在检测乳腺癌病人外周血微转移中的应用价值

目的分析并评价乳腺小黏蛋白(SBEM)基因在检测乳腺癌病人外周血微转移中的应用价值。方法应用逆转录聚合酶链反应(RT-PCR)分析乳腺癌病人、结/直肠癌病人、女性胃癌、乳腺纤维腺瘤病人以及健康人外周血中SBEM基因的表达。结果全部111例乳腺癌病人外周血中有59例SBEM基因表达呈阳性; 对照组外周血中SBEM基因未见阳性表达。乳腺癌病人外周血阳性表达率与对照组相比差异显著(P<0.05)。SBEM基因的阳性表达与病人淋巴结转移以及TNM分期之间具有相关性(P<0.01); 而与病人年龄大小、病理类型、原发肿瘤体积、雌激素受体以及孕激素受体等无相关性(P>0.05)。结论SBEM基因在乳腺癌病人的外周血中呈特异性表达, 可作为乳腺癌病人外周血中微转移检测以及分析预后的可靠指标之一。
顾旭辨治冠脉支架术后心绞痛经验总结

或痉挛);②PCI 治疗为不完全血运重建,还有其他冠脉病变狭窄未能解除;③PCI 后再狭窄。对第一个原因可以再行冠状动脉造影检查,必要时再行PCI,但介入风险加大,也加重患者经济负担;而后两种情况往往病变较重,无法再行PCI,即使行PCI,效果也很差,甚至行冠脉搭桥治疗效果也不甚理想。
复方红豆杉胶囊致严重肌无力救治体会

复方红豆杉胶囊具有较好的抗肿瘤作用,广泛用于治疗中晚期恶性肿瘤。笔者临床使用复方红豆杉胶囊时出现1例严重肌无力不良反应,经过积极治疗已基本恢复,现报道如下。
三级甲等中医院与社区医院共建中医服务平台优势探讨

三甲中医院与社区共建中医诊疗平台是新形势下社区居民的健康需求,笔者从其中优势的人才培养、资源优化、科室建设、便民就医、慢性病防治等方面加以阐述,并且认为此项平台建设是三甲中医院、社区医院、社区居民“三赢”的工程,值得深入建设和完善。
A Multi-model Approach for Soft Sensor Development Based on Feature Extraction Using Weighted Kernel Fisher Criterion

Multi-model approach can significantly improve the prediction performance of soft sensors in the proc-ess with multiple operational conditions. However, traditional clustering algorithms may result in overlapping phe-nomenon in subclasses, so that edge classes and outliers cannot be effectively dealt with and the modeling result is not satisfactory. In order to solve these problems, a new feature extraction method based on weighted kernel Fisher criterion is presented to improve the clustering accuracy, in which feature mapping is adopted to bring the edge classes and outliers closer to other normal subclasses. Furthermore, the classified data are used to develop a multi-ple model based on support vector machine. The proposed method is applied to a bisphenol A production process for prediction of the quality index. The simulation results demonstrate its ability in improving the data classification and the prediction performance of the soft sensor.
宫颈小细胞癌1例并文献复习

目的:探讨宫颈小细胞癌(SCCC)的临床病理特点、诊断、治疗和预后。方法:通过回顾分析2011年6月中国人民解放军海军总医院收治的1例SCCC患者的临床资料,探讨其临床病理特征及预后。结果:患者为55岁绝经后女性,临床表现为绝经后接触性阴道出血,伴右侧腰部胀痛。患者出现症状半年后于当地医院就诊,见宫颈异常肿物,病理活检提示为SCCC。我院病理会诊结果仍为SCCC,超声及肺部CT影像学检查提示,肺部转移及宫旁浸润,压迫右侧输尿管。患者按EP方案给予化疗1次,于2012年5月死亡。结论:SCCC癌恶性度高,预后差,死亡率高。其确诊主要依靠病理组织形态学和免疫组化。目前多采用手术、化疗和放疗联合综合治疗。
有机肥与覆盖对苏北滩涂重度盐渍土壤水盐调控效应分析

苏北地区滩涂资源丰富，拥有占全国1/4以上的滩涂面积，是非常重要的后备土地资源，同时，其开发利用历史悠久，已取得了巨大的社会经济效益。但从目前研究看来，土壤质量偏低依然是制约苏北滩涂开发利用的主要障碍因子。土壤盐渍化，尤其是重度盐渍化，作为影响滩涂土壤质量的主要障碍因子之一，严重抑制了土壤生产力的发挥，导致土地生产效率普遍偏低。因此，采取适当措施对土壤水盐运移过程进行有效调控、消减盐碱障碍因子是滩涂农田地力提升、滩涂土地资源功能发挥的基础。
以单侧耳聋为前驱表现的后循环脑梗死2例

脑梗死是神经科的常见病、多发病,但以感音神经性听力损失为前驱表现的后循环脑梗死少见,一旦误诊,或可能危及患者生命。国内仅有刘丽君等报告过双耳聋为首发症状的基底动脉部分闭塞一例,我科自2012年3月收治2例,初诊均诊断为突发性耳聋.
帕金森病的冲动控制障碍

帕金森病(Parkinson`s disease,PD)是一种中老年人常见的运动障碍疾病,以黑质多巴胺能神经元缺失和路易小体形成为病理特征。临床表现为静止性震颤、运动迟缓、肌强直和姿势步态异常。PD以多巴胺能药物治疗为主,而且最有效。PD除典型运动症状外,还伴有一些非运动症状,包括冲动控制障碍(impulse control disorders,ICDs), ICDs是一个多维概念,是一组反复、过度的精神行为障碍。既包括对问题缺乏了解之前的贸然行动,缺乏思考的冒失反应,还包括难以抑制的对无关刺激或不当刺激的鲁莽行为。表现为无法控制的冲动和欲望,进而做出一系列对自己和他人有害的异常行为,包括病理性赌博(patho-logical gambling,PG)、强迫性购物、性欲亢进、强迫性进食、病理性纵火、拔毛症、偷窃癖、网络成瘾等。本文将对ICDs的流行病学、病因、临床表现、诊断及治疗等方面做一简要综述。