mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Novel WDM-PON architecture for simultaneous transmission of unicast data and multicast services

We propose a novel wavelength-division multiplexed passive optical network (WDM-PON) to simultaneously transmit unicast data and multicast services with upstream data re-modulation in optical network units (ONUs). For each wavelength channel in the optical line terminal (OLT), the downstream unicast data are applied to one arm of a dual-parallel Mach-Zehnder modulator (DPMZM) to generate baseband unicast non-return-to-zero (NRZ) signal. A radio frequency (RF) control signal is applied to the other arm to present two un-modulated sidebands for multicast data modulation in a differential phase-shift keying (DPSK) format. The flexible and dynamic multicast services are realized by simply switching the RF control signal on or off. The proposed scheme is experimentally demonstrated with 1.25-Gb/s downstream unicast, multicast, and upstream data
Confocal imaging of Bim translocation to endoplasmic reticulum during DHA-induced ASTC-a-1 pell apoptosis

Bim, a proapoptotic member of Bcl-2 family, plays an important role in cell apoptosis. It is generally thought that Bim translocates to mitochondria in response to apoptotic stimuli. We use confocal microscopy to image the temporal-spatial dynamics of Bim during dihydroartemisinin (DHA) induced human lung adenocarcinoma (ASTC-a-1) cell apoptosis. Interestingly, we find that DHA induces Bim translocation to endoplasmic reticulum (ER) rather than mitochondria, implying that Bim-ER pathway might be involved in the DHA-induced ASTC-a-1 cell apoptosis
Novel orthogonal modulation format DRZ-FSK/DPSK for high-speed long-haul optical communication

We propose a novel advanced orthogonal modulation format dark return-to-zero frequency shift keying/differential phase shift keying (DRZ-FSK/DPSK) and its realization scheme. The DRZ-FSK/DPSK is generated by the combination of a 40-Gb/s return-to-zero (RZ) signal and a DRZ signal which is converted from the RZ using a semiconductor optical amplifier (SOA) based on nonlinear cross polarization rotation (XPR) and then re-modulated by high-bit-rate DPSK at 40 Gb/s. The feasibility of the scheme is experimentally demonstrated. Bit error rate (BER) results of the total 80-Gb/s DRZ-FSK/DPSK orthogonal modulation signal with a subsequent 100-km single-mode fiber (SMF) transmission link show its potential for future high-speed long-haul optical communication
Simultaneous multichannel NRZ-to-RZ format conversion of 4-ASK signal based on phase-intensity hybrid modulation and dispersion compensation fiber

We propose and investigate a novel technique to realize non-return-to-zero (NRZ) to return-to-zero (RZ) format conversion of a multichannel 4-ary amplitude shift keying (4-ASK) signal. The proposed format converter composed of two modulators and a dispersion compensating fiber (DCF) is theoretically investigated using numerical simulation as basis. Research shows that a 4-channel 20-Gb/s NRZ-4-ASK signal can be converted to a RZ-4-ASK signal simultaneously without wavelength shifting and signal quality degradation, with the converted signal multiplexed to 40 Gb/s
A novel model of cholesterol efflux from lipid-loaded cells

Cholesterol efflux from lipid-loaded cells is a key athero-protective event that counteracts cholesterol uptake. The imbalance between cholesterol efflux and uptake determines the prevention or development of atherosclerosis. Many proteins and factors participate in the cholesterol efflux event. However, there are currently no systematic models of reverse cholesterol transport (RCT) that include most RCT-related factors and events. On the basis of recent research findings from other and our laboratories, we propose a novel model of one center and four systems with coupling transportation and networking regulation. This model represents a common way of cholesterol efflux; however, the systems in the model consist of different proteins/factors in different cells. In this review, we evaluate the novel model in vascular smooth muscle cells (VSMCs) and macrophages, which are the most important original cells of foam cells. This novel model consists of 1) a caveolae transport center, 2) an intracellular trafficking system of the caveolin-1 complex, 3) a transmembrane transport system of the ABC-A1 complex, 4) a transmembrane transport system of the SR-B1 complex, and 5) an extracelluar trafficking system of HDL/Apo-A1. In brief, the caveolin-1 system transports cholesterol from intracellular compartments to caveolae. Subsequently, both ABC-A1 and SR-B1 complex systems transfer cholesterol from caveolae to extracellular HDL/Apo-A1. The four systems are linked by a regulatory network. This model provides a simple and concise way to understand the dynamic process of atherosclerosis
Adiponectin resistance and vascular dysfunction in the hyperlipidemic state

Insulin plays an important role in the stimulation of vascular nitric oxide production, with both short term (vasomotility and antithrombotic effects) and long term (smooth muscle cell growth and migration inhibition) benefits. Impaired vasodilatory response to insulin, the hallmark of vascular insulin resistance (IR), has important implications for circulatory pathophysiology. An association between adipokines and IR has been observed in both diabetic and nondiabetic states. Adiponectin (APN) is an insulin-sensitizing adipokine known to stimulate skeletal muscle fatty acid (FA) oxidation and reduce lipid accumulation. Recent demonstrations of potential cross-talk between APN and insulin in vascular function regulation are particularly interesting. The lipid accumulation observed after chronic high-fat (HF) diets and in the obese state may reduce vascular response to APN, a pathologic state termed as APN resistance. This review highlights the importance of insulin sensitivity and APN activity in the maintenance of endothelial function. It explores the relationships between vascular IR and APN resistance in the hyperlipidemic pathological condition, representative of the metabolic syndrome. The investigation of vascular insulin and APN resistance provides not only better understanding of vascular pathophysiology, but also an opportunity for therapeutic targeting in individuals affected by the metabolic syndrome
Analysis and Optimization of Cooling Channels in ITER Blanket Module

Thermal hydraulic analysis was performed for the 2004 ITER blanket design, which was based on the fabrication methods of forging, drilling and welding. Results show that, in the original design, the flow distribution in radial holes was far from uniform because different flow drivers were used in the radial holes. -Improvement of the flow driver is proposed in this study. With the optimization of the flow drivers, it is clearly shown that the total pressure drop decreases and a better velocity distribution in radial holes is obtained. The more uniform heat transfer coefficient among the radial holes is beneficial for reducing thermal stress
Effect of Low-frequency Power on F, CF2 Relative Density and F/CF2 Ratio in Fluorocarbon Dual-Frequency Plasmas

Effect of low-frequency power on F, CF_2 relative density and F/CF2 ratio, in C_2F_6, C_4F_8 and CHF_3 dual-frequency capacitively couple discharge'driven by the power of 13.56 MHz/2 MHz, was investigated by using optical emission spectroscopy. High F, CF2 relative density and high F/CF2 ratio were obtained in a CHF_3 plasma. But for C_2F_6 and C_4F_8 plasmas, the F, CF2 relative density and F/CF2 ratio all decreased significantly due to the difference in both reactive paths and reactive energy. The increase of LF power caused simultaneous increase of F and CF_2 radical relative densities in C_4F_8 and CHF_3 plasmas, but led to increase -of F with the decrease in CF_2 relative densities in C_2F_6 plasma due to the increase of lower energy electrons and the decrease of higher energy electrons in electron energy distribution function (EEDF)
悉尼大学DCH项目对儿科医学继续教育工作的启示

<正>2009年,笔者有幸参加了悉尼大学儿童医院为期1年的DCH(Diploma in Child Health,儿童健康文凭)继续教育项目培训,从学习中得到以下几点对目前儿科继续教育工作的启迪,供有兴趣的同行们参考
房间隔缺损介入封堵术相关性心律失常

<正>经导管介入封堵先天性心脏病继发孔型房间隔缺损已逐渐成为主要的治疗手段,但对房间隔缺损介入封堵后出现的心律失常鲜有报道[1-4].本研究总结分析了我科近2年房间隔缺损介入封堵术出现的心律失常,报道如下
Loss of chromosome 9p21 and decreased p16 expression correlate with malignant gastrointestinal stromal tumor

AIM: To investigate loss of heterozygosity (LOH) of chromosome 9p21 and the prognostic relevance of p16 expression in gastrointestinal stromal tumor (GIST). METHODS: Fifty-one GIST patients (30 men and 21 women; median age 59 years; range 29-80 years) treated surgically within a 10-year period were grouped by aggressive behavior risk (17 with very low and low, 14 intermediate, and 20 high risk). GISTs were characterized immunohistochemically and evaluated for LOH of 9p21 by microsatellite analysis at D9S1751, D9S1846, D9S942, and D9S1748. LOH of 9p21 and immunohistochemical expression of p16 protein encoded at 9p21 were correlated with clinicopathological pararrieters, and the prognostic significance of p16 alterations was evaluated. RESULTS: Thirty-one (63.3%) cases showed LOH with at least one microsatellite marker. LOH frequency was 37.0% at D9S1751, 37.5% at D9S1846, 42.1% at D9S942, and 24.2% at D9S1748. There was a higher LOH frequency of D9S942 in high-risk than in non-highrisk tumors (P < 0.05, x~2 = 4.47). Gender, age, tumor size and site were not correlated with allelic loss. Ninety percent (18/20) of the GIST patients in the high risk group showed LOH with at least one of the 9p21 markers, while 57.1% (8/14) in the intermediate risk group and 33.3% (5/15) in the very low and low risk groups, respectively (P < 0.05, x~2 = 12.16). Eight (28.5%) of 31 patients with LOH and 1 (5.6%) of 18 patients without LOH died of the disease during the follow-up period. Loss of p16 protein expression occurred in 41.2%, but in 60% of the high risk group and 23.5% of the very low and low risk groups (P < 0. 05, X~2 = 4.98). p16 loss was associated with poor prognosis (P < 0.05, x~2 = 4.18): the 3- and 5-year overall survival rates were 84.8% and 70.8% for p16-negative and 100% and 92.0% for pl6-positive patients, respectively. CONCLUSION: LOH at 9p21 appears to play an important role in GIST progression; decreased p16 expression in GIST is highly predictive of poor outcome
Association of NOD1 (CARD4) insertion/deletion polymorphism with susceptibility to IBD: A meta-analysis

AIM: To find evidences about whether NOD1/CARD4 insertion/deletion polymorphism is associated with inflammatory bowel disease by meta-analysis. METHODS: We surveyed the studies on the association of NOD1/CARD4 insertion/deletion polymorphism with inflammatory bowel disease in PubMed. Meta-analysis was performed for genotypes GG/T vs T/T, GG/GG vs T/T, GG/T + GG/GG vs T/T, GG/GG vs T/T + GG/T, and GG allele vs T allele in a fixed/random effect model. RESULTS: We identified 8 studies (6439 cases and 4798 controls) in Caucasian populations using PubMed search. We found no association between NOD1/CARD4 insertion/deletion polymorphism and inflammatory bowel disease, Crohn's disease, and ulcerative colitis. Stratification of cases by age showed that NOD1/CARD4 insertion/deletion polymorphism was associated with inflammatory bowel disease in younger age group at onset (< 40 years) (GG vs T: OR = 0.68, 95% CI: 0.50-0.93, P = 0.02; GG/T + GG/GG vs T/T: OR = 0.71, 95% CI: 0.59-0.85, P = 0.0003). CONCLUSION: This meta-analysis demonstrates an association between NOD1/CARD4 insertion/deletion polymorphism and inflammatory bowel disease in the younger age group at onset (< 40 years) in Caucasian populations
Multi-site abdominal tuberculosis mimics malignancy on ~(18)F-FDG PET/CT: Report of three cases

~(18)F-fluorodeoxyglucose positron emission/computed tomography (~(18)F-FDG PET/CT) imaging, an established procedure for evaluation of malignancy, shows an increased ~(18)F-FDG uptake in inflammatory conditions. We present three patients with abdominal pain and weight loss. Conventional imaging studies indicated that abdominal neoplasm and ~(18)F-FDG PET/CT for assessment of malignancy showed multiple lesions with intense ~(18)F-FDG uptake in abdomen of the three cases. However, the three patients were finally diagnosed with multi-site abdominal tuberculosis (TB). Of them, two were diagnosed with TB by pathology, one was diagnosed with TB clinically. They recovered after anti-TB therapy. Few reports on accumulation of ~(18)F-FDG in abdominal TB are available in the literature. A high index of suspicion is necessary to achieve an early diagnosis and a better outcome of the disease
Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk: A meta-analysis

AIM: To evaluate the contribution of alcohol dehydrogenase-lB (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) polymorphisms to the risk of esophageal cancer. METHODS: Nineteen articles were included by searching MEDLINE, EMBASE and the Chinese Biomedical Database, 13 on ADH1B and 18 on ALDH2. We performed a meta-analysis of case-control studies including 13 studies on ADH1B (cases/controls: 2390/7100) and 18 studies on ALDH2 (2631/6030). RESULTS: The crude odds ratio [OR (95% confidence interval)] was 2.91 (2.04-4.14) for ADH1B*1/*1 (vs ADH1B*2/*2) and 1.32 (1.17-1.49) for ADH1B*1/*2. The crude OR for ALDH2*1/*2 (vs ALDH2*1/*1) was 2.52 (1.76-3.61). ADH1B*1/*1 increased the risk of esophageal cancer among never/rare [1.56 (0.93-2.61)], moderate [2.71 (1.37-5.35)], and heavy drinkers [3.22 (2.27-4.57)]. ADH1B*1/*2 was associated with a modest risk among moderate drinkers [1.43 (1.09-1.87)]. ALDH2*1/*2 increased the risk among never/rare [1.28 (0.91-1.80)], moderate [3.12 (1.95-5.01)], and heavy [7.12 (4.67-10.86)] drinkers, and among ex-drinkers [5.64 (1.57-20.25)]. ALDH2*2/*2 increased the risk among drinkers [4.42 (1.72-11.36)]. ADH1B*1/*1 plus ALDH2*1/*2 was associated with the highest risk for heavy drinkers [12.45 (2.9-53.46)]. The results of the meta-regression analysis showed that the effects of AD-H1B*1/*1 and ALDH2*1/*2 increased with the level of alcohol consumption. ALDH2*1/*2 was associated with a high risk among Taiwan Chinese and Japanese drinkers, as opposed to a moderate risk among drinkers in high-incidence regions of Mainland China. ADH1B*1/*1 in heavy drinkers and ALDH2*1/*2 in moderate-to-heavy drinkers was associated with similarly high risk among both men and women. CONCLUSION: ADH1B/ALDH2 genotypes affect the risk of esophageal cancer, and the risk is modified by alcohol consumption, ethnicity, and gender
Obstructive sleep apnea syndrome and fatty liver: Association or causal link

Obstructive sleep apnea (OSA) is a complex disorder that consists of upper airway obstruction, chronic intermittent hypoxia and sleep fragmentation. OSA is well known to be associated with hypoxia, insulin resistance and glucose intolerance, and these factors can occur in the presence or absence of obesity and metabolic syndrome. Although it is well established that insulin resistance, glucose intolerance and obesity occur frequently with non-alcoholic fatty liver disease (NAFLD), it is now becoming apparent that hypoxia might also be important in the development of NAFLD, and it is recognized that there is increased risk of NAFLD with OSA. This review discusses the association between OSA, NAFLD and cardiovascular disease, and describes the potential role of hypoxia in the development of NAFLD with OSA
Design of 16S rRNA gene primers for 454 pyrosequencing of the human foregut microbiome

AIM: To design and validate broad-range 16S rRNA primers for use in high throughput sequencing to classify bacteria isolated from the human foregut microbiome. METHODS: A foregut microbiome dataset was constructed using 16S rRNA gene sequences obtained from oral, esophageal, and gastric microbiomes produced by Sanger sequencing in previous studies represented, by 219 bacterial species. Candidate primers evaluated were from the European rRNA database. To assess the effect of sequence length on accuracy of classification, 16S rRNA genes of various lengths were created by trimming the full length sequences. Sequences spanning various hypervariable regions were selected to simulate the amplicons that would be obtained using possible primer pairs. The sequences were compared with full length 16S rRNA genes for accuracy in taxonomic classification using online software at the Ribosomal Database Project (RDP). The universality of the primer set was evaluated using the RDP 16S rRNA database which is comprised of 433306 16S rRNA genes, represented by 36 phyla. RESULTS: Truncation to 100 nucleotides (nt) downstream from the position corresponding to base 28 in the Escherichia coli 16S rRNA gene caused misclassification of 87 (39.7%) of the 219 sequences, compared with misclassification of only 29 (13.2%) sequences with truncation to 350 nt. Among 350-nt sequence reads within various regions of the 16S rRNA gene, the reverse read of an amplicon generated using the 343F/798R primers had the least (8.2%) effect on classification. In comparison, truncation to 900 nt mimicking single pass Sanger reads misclassified 5.0% of the 219 sequences. The 343F/798R amplicon accurately assigned 91.8% of the 219 sequences at the species level. Weighted by abundance of the species in the esophageal dataset, the 343F/798R amplicon yielded similar classification accuracy without a significant loss in species coverage (92%). Modification of the 343F/798R primers to 347F/803R increased their universality among foregut species. Assuming that a typical polymerase chain reaction can tolerate 2 mismatches between a primer and a template, the modified 347F and 803R primers should be able to anneal 98% and 99.6% of all 16S rRNA genes in the RDP database. CONCLUSION: 347F/803R is the most suitable pair of primers for classification of foregut 16S rRNA genes but also possess universality suitable for analyses of other complex microbiomes
微创经皮肾镜钬激光碎石治疗输尿管上段结石110例报告

目的探讨腔内治疗输尿管上段结石微创,安全,有效的方法.方法 110例患者行连续硬脊膜外阻滞麻醉后,微创经皮肾穿刺,建立手术通道,插入肾镜(Wolf F8.5~11.5)至输尿管上段,窥见结石后,用能量/频率为0.2~3.0J/5~20Hz的钬激光机(设置功率0.6~1.2J/6~10Hz),直径为360μm的钬激光传导光纤将结石粉碎,同时切除输尿管息肉.术后保留尿管2~5d;保留肾造瘘管2~5d,保留双J管2~4周.记录手术时间,术后住院时间,结石排净时间以及手术并发症.结果在110例患者中,手术时间为30~70min,平均45min.术后住院时间为5~11d,平均7d.结石排净时间3~5周,平均3.5周.术中彻底切除输尿管息肉,无输尿管穿孔,大出血等严重并发症.结论微创经皮肾镜钬激光碎石治疗输尿管上段结石是一种微创,安全,有效的方法
瑞芬太尼靶控浓度输注在支撑喉镜下声带息肉摘除术中的应用

目的探讨瑞芬太尼靶控效应室浓度输注用于支撑喉镜下声带息肉摘除术的安全性和可靠性.方法择期支撑喉镜下声带息肉摘除术患者共40例,随机分为瑞芬太尼组(R组,n=20)与芬太尼组(F组,n=20),R组采用静注咪达唑仑50μg/kg,维库溴铵0.15mg/kg,丙泊酚1.5~2mg/kg,瑞芬太尼则以4.0ng/mL为效应室浓度静脉输注;F组则以咪达唑仑50μg/kg,芬太尼5μg/kg,维库溴铵0.15mg/kg,丙泊酚1.5~2mg/kg,进行麻醉诱导.两组均吸入1.5%异氟醚维持麻醉深度,R组于手术结束撤除支撑喉镜时停止静脉输注.记录诱导前,气管插管前,置入支撑喉镜时3个时点的脉搏,平均动脉压(MAP)及手术进行期间患者的体动反应.记录麻醉诱导至意识丧失时间,呼唤患者睁眼时间.结果 R组患者呼唤睁眼时间短于F组(P<0.01).与术前相比,R组MAP下降幅度明显大于F组(P<0.05).而置入支撑喉镜时,F组心率变化幅度与R组相比差异存在显著性,明显高于R组(P<0.05).结论瑞芬太尼靶控效应室浓度输注用于支撑喉镜下声带息肉摘除术是一种可靠的选择
腹腔镜胆总管探查取石术的临床分析

目的分析腹腔镜胆总管探查取石术的手术方法和操作要点,探讨其适应证及并发症的预防,为今后临床腹腔镜胆总管探查取石术的治疗提供依据.方法回顾性分析2008年11月~2009年11月该院76例行腹腔镜胆总管探查取石术患者的临床资料,对手术方法,治疗结果及其注意事项进行总结.结果 76例患者均在胆道镜的配合下行腹腔镜胆总管探查取石术,其中行腹腔镜胆总管切开取石术50例,腹腔镜下经胆囊管胆总管探查术26例.胆总管切开后一期缝合42例,胆总管切开取石后置T管引流20例,1例患者术后出现胆漏,所有患者术后经B超或者T管造影检查证实无残余结石.结论腹腔镜胆总管探查取石术创伤小,安全可行,掌握腹腔镜胆总管探查取石术的手术方式和适应证,做好并发症的预防和及时处理对治疗胆总管结石具有重要意义
高龄前列腺增生患者2μm激光切除术的围手术期处理

目的探讨2μm激光前列腺切除术治疗高龄前列腺增生患者的围手术期处理.方法 2009年3月~2009年9月采用2μm激光治疗高龄前列腺增生患者31例,年龄为83~95岁,平均87.8岁.激光功率为70W.观察围手术期手术时间,术后拔除尿管时间和膀胱冲洗时间.比较术前,术后血红蛋白和电解质的变化.结果手术时间32~60min,平均45min;拔除尿管时间(2±1)d,膀胱冲洗时间为6h.围手术期未发现心,脑及肺等严重并发症.术前,术后血红蛋白和电解质的无明显变化.结论 2μm激光在治疗高龄前列腺增生患者的优势主要表现在围手术期安全,手术时间短,明显缩短了拔除尿管和膀胱冲洗时间,术后恢复快
胆总管十二指肠乳头旁瘘伴胆管结石44例临床分析

目的探讨胆总管十二指肠乳头旁瘘(PCF)伴胆管结石的治疗.方法 44例经十二指肠镜和经内镜逆行胰胆管造影(ERCP)确诊,Ⅰ型29例,Ⅱ型15例.11例手术治疗,其中胆总管切开取石加T管引流2例,胆-肠内引流7例,胆-肠内引流加部分肝叶切除术2例;内镜治疗27例,其中经内镜括约肌切开术(EST)5例,EST加网篮碎石取石11例,瘘口气囊取石4例,瘘口单纯网篮取石5例,EST加子母镜下激光碎石及网篮取石2例;未作介入治疗6例.结果手术及内镜下治疗均取出结石,随访半年,再发胆管炎或胆管结石,手术组0,内镜组4例,未介入组1例,3组比较差异无显著性.结论十二指肠镜和ERCP是确诊的关键,治疗的选择应综合考虑,内镜治疗为首选,胆管情况复杂或内镜治疗失败则外科手术,无结石残留可内科治疗
胃镜下钛夹,热极凝固及注射治疗急性非静脉曲张上消化道出血的疗效比较

目的评价胃镜下钛夹,热极凝固及注射治疗急性非静脉曲张上消化道出血的疗效.方法经胃镜确诊为急性非静脉曲张上消化道出血85例,随机分成钛夹组(n=29),热极凝固组(n=28)和注射组(n=28)对出血灶进行治疗,评价3种治疗方法的止血率和再出血率的差异.结果钛夹,热极凝固及注射组首次止血率分别为100.00%,96.43%,92.86%,差异无显著性(P>0.05).钛夹组和热极凝固组各有1例发生再次出血,再出血率分别为3.45%,3.70%,两组再出血率差异无显著性(P>0.05).注射组中有6例发生再出血,再出血率23.08%,高于钛夹组和热极凝固组,差异有显著性(P<0.05).结论胃镜下钛夹与热极凝固治疗非静脉曲张上消化道出血疗效相当,优于注射治疗
On-demand coding-aware routing in wireless Mesh networks

Network coding, which exploits the broadcast nature of wireless medium, is an effective way to improve network performance in wireless multi-hop networks, but the first practical wireless network coding system COPE cannot actively detect a route with more coding opportunities and limit the coding structure within two-hop regions. An on-demand coding-aware routing scheme (OCAR) for wireless Mesh networks is proposed to overcome the limitations specified above by actively detecting a route with more coding opportunities along the entire route rather than within two-hop regions. Utilizing more coding opportunities tends to route multiple flows 'close to each other' while avoiding interference requires routing multiple flows 'away from each other'. OCAR achieves a tradeoff by adopting R_(CAIA) as routing metric in route discovery, which is not only coding-aware but also considers both inter and intra flow interference. Simulation results show that, compared with Ad-hoc on-demand distance vecfor routing (AODV) and AODV+COPE, OCAR can find more coding opportunities, thus effectively increase network throughput, reduce end to end delay and alleviate network congestion
反向Luddloff截骨术治疗严重?外翻

[目的]探讨反向Luddloff截骨轴心点旋转固定治疗严重外翻的效果.[方法]对26例(33足)严重外翻畸形患者采用反向Luddloff截骨轴心点旋转固定对重度外翻进行矫治.[结果]26例(33足)均获随访,时间最长40个月,最短11个月(平均25.5个月).优20足,良3足,差1足.X线片示?母跖角为0°5°,跖骨角度为3°7°,半脱位纠正,趾内旋角05°.[结论]反向Luddloff截骨轴心点旋转固定治疗严重外翻矫正效果良好,在矫正外翻的同时,矫正趾内旋畸形和前足横弓塌陷.此方法不会影响跖骨的长度,不需植骨,截骨端接触面积大,稳定性好,利于愈合,适用于不同年龄的严重外翻畸形
查尔酮类化合物生物活性研究新进展

查尔酮类化合物以1,3-二苯基丙烯酮为基本骨架结构,为多种药用植物的有效成分,具有广泛的生物学活性.此文综述了查尔酮类化合物的抗肿瘤,抗炎,抗菌,抗HIV等多种生物学活性研究的新进展
Robust estimation algorithm for multiple-structural data

This paper proposes a robust method of parameter estimation and data classification for multiple-structural data based on the linear error in variable (EIV) model. The traditional EIV model fitting problem is analyzed and a robust growing algorithm is developed to extract the underlying linear structure of the observed data. Under the structural density assumption, the C-step technique borrowed from the Rousseeuw's robust MCD estimator is used to keep the algorithm robust and the mean-shift algorithm is adopted to ensure a good initialization. To eliminate the model ambiguities of the multiple-structural data, statistical hypotheses tests are used to refine the data classification and improve the accuracy of the model parameter estimation. Experiments show that the efficiency and robustness of the proposed algorithm
Low-complexity method for DOA estimation based on ESPRIT

A low-complexity method for direction of arrival (DOA) estimation based on estimation signal parameters via rotational invariance technique (ESPRIT) is proposed. Instead of using the cross-correlation vectors in multistage Wiener filter (MSWF), the orthogonal residual vectors obtained in conjugate gradient (CG) method span the signal subspace used by ESPRIT. The computational complexity of the proposed method is significantly reduced, since the signal subspace estimation mainly needs two matrixvector complex multiplications at the iteration of data level. Furthermore, the prior training data are not needed in the proposed method. To overcome performance degradation at low signal to noise ratio (SNR), the expanded signal subspace spanned by more basis vectors is used and simultaneously renders ESPRIT yield redundant DOAs, which can be excluded by performing ESPRIT once more using the unexpanded signal subspace. Compared with the traditional ESPRIT methods by MSWF and eigenvalue decomposition (EVD), numerical results demonstrate the satisfactory performance of the proposed method