mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Parallel algorithm and its convergence of spatial domain decomposition of discrete ordinates method for solving radiation heat transfer problem

To improve the computational efficiency and hold calculation accuracy at the same time, we study the parallel computation for radiation heat transfer. In this paper, the discrete ordinates method (DOM) and the spatial domain decomposition parallelization (DDP) are combined by message passing interface (MPI) language. The DDP–DOM computation of the radiation heat transfer within the rectangular furnace is described. When the result of DDP–DOM along one-dimensional direction is compared with that along multi-dimensional directions, it is found that the result of the latter one has higher precision without considering the medium scattering. Meanwhile, an in-depth study of the convergence of DDP–DOM for radiation heat transfer is made. Analyzing the cause of the weak convergence, we relate the total number of iteration steps when the convergence is obtained to the number of sub-domains. When we decompose the spatial domain along one-, two- and three-dimensional directions, different linear relationships between the number of total iteration steps and the number of sub-domains will be possessed separately, then several equations are developed to show the relationships. Using the equations, some phenomena in DDP–DOM can be made clear easily. At the same time, the correctness of the equations is verified.
A Rare Case of Abdominal Cocoon Presenting as Umbilical Hernia

Abdominal cocoon (AC) is a rare condition, that leading to acute or chronic small bowel obstruction, characterized by a total or partial encapsulation ofthe small bowel by a fibrous membrane or sac-like cocoon, sometimes colon, uterus or accessories are encased in. The disease is characterized as either primary or secondary to other causes. The main reported clinical manifestations of AC are acute/subacute complete/partial intestinal obstruction and abdominal mass.[1] Here, we report a rare case of AC presenting as umbilical hernia, and to our knowledge, it is only a few cases of this entity have been reported previously. Even though preoperative diagnosis of AC is difficult and normally laparotomy is the main solution, in our case, we chose the method which combines laparoscopy with open surgery, it solved patient problem quickly and efficiently, and that further confirmed laparoscopic surgery has great significance in diagnosis and treatment of AC.
Macroscopic and Histological Evaluations of Meniscal Allograft Transplantation Using Gamma Irradiated Meniscus: A Comparative in Vivo Animal Study

Background: Many studies suggest that the gamma irradiation decreases allograft strength in a dose-dependent manner. However, no study has demonstrated that this decrease in strength translates into higher failure rate in meniscal allograft transplantation (MAT). The aim of this study was to investigate the effects of gamma irradiation on macroscopic and histological alterations of transplanted meniscal tissue and joint cartilage after MAT. Methods: Medial total meniscectomies were performed on the right knees of 60 New Zealand white rabbits. All meniscal allografts were divided into three groups (20 in each group) and then sterilized with 0 Mrad, 1.5 Mrad, or 2.5 Mrad of gamma irradiation. For each group, 5 menisci were randomly chosen for scanning electron microscopic (SEM) analysis and the remaining 15 were prepared for MAT surgeries. Forty-five right knees received MAT surgeries (0 Mrad group, 1.5 Mrad group,2.5 Mrad group, 15 in each group), whereas the remaining 15 only received medial meniscectomy (Meni group). The left knees of the Meni group were chosen as the Sham group (n = 15). All the rabbits were sacrificed at week 24 postoperatively. Cartilage of the medial compartment of each group was evaluated macroscopically using the International Cartilage Repair Society (ICRS) score and then histologically using the Mankin score based on the Masson Trichrome staining. Results: The SEM analysis confirmed that the meniscal collagen fibers would be significantly damaged as the dose of gamma irradiation increased. At week 24, the overall scores of macroscopic evaluations of the transplanted meniscal tissue showed no significant differences among the three groups receiving MAT surgeries, except for 2 in the 2.5 Mrad group presented partial radial tears at midbody. The ICRS scores and the Mankin scores showed the lowest in the Sham group and the highest in the Meni group (P < 0.05). For the three groups receiving MAT surgeries, the 2.5 Mrad group showed significant higher ICRS scores and Mankin scores than both the 0 Mrad group and the 1.5 Mrad group (P < 0.05). Whereas the 1.5 Mrad group presented similar results to the 0 Mrad group concerning both the ICRS scores and the Mankin scores. Conclusions: The current in vivo animal study proved that although the meniscal collagen fibers were damaged after gamma irradiation, the failure rate of MAT surgeries might not significantly increase if the irradiation dose was <1.5 Mrad for New Zealand white rabbits.
Human Sulfatase-1 Improves the Effectiveness of Cytosine Deaminase Suicide Gene Therapy with 5-Fluorocytosine Treatment on Hepatocellular Carcinoma Cell Line HepG2 In Vitro and In Vivo

Background: Human sulfatase-1 (Hsulf-1) is an endosulfatase that selectively removes sulfate groups from heparan sulfate proteoglycans (HSPGs), altering the binding of several growth factors and cytokines to HSPG to regulate cell proliferation, cell motility, and apoptosis. We investigated the role of combined cancer gene therapy with Hsulf-1 and cytosine deaminase/5-fluorocytosine (CD/5-FC) suicide gene on a hepatocellular carcinoma (HCC) cell line, HepG2, in vitro and in vivo. Methods: Reverse transcription polymerase chain reaction and immunohistochemistry were used to determine the expression of Hsulf-1 in HCC. Cell apoptosis was observed through flow cytometry instrument and mechanism of Hsulf-1 to enhance the cytotoxicity of 5-FC against HCC was analyzed in HCC by confocal microscopy. We also establish a nude mice model of HCC to address the effect of Hsulf-1 expression on the CD/5-FC suicide gene therapy in vivo. Results: A significant decrease in HepG2 cell proliferation and an increase in HepG2 cell apoptosis were observed when Hsulf-1 expression was combined with the CD/5-FC gene suicide system. A noticeable bystander effect was observed when the Hsulf-1 and CD genes were co-expressed. Intracellular calcium was also increased after HepG2 cells were infected with the Hsulf-1 gene. In vivo studies showed that the suppression of tumor growth was more pronounced in animals treated with the Hsulf-1 plus CD than those treated with either gene therapy alone, and the combined treatment resulted in a significant increase in survival. Conclusions: Hsulf-1 expression combined with the CD/5-FC gene suicide system could be an effective treatment approach for HCC.
国际护理术语分类体系发展概况及其对我国护理的启示

随着计算机技术在护理中的广泛应用,护理信息学已逐渐发展成为一个新兴的专业发展方向,涵盖了信息技术在护理中的运用、护理信息标准化研究、基于电子健康档案的循证护理研究等诸多方面。其中,护理信息标准化是该学科发展的基础,只有作为信息交换的元数据达到标准化才能实现信息资源的充分共享和利用。护理信息标准化包括护理术语标准化、护理工作流程标准化、护理数据标准化等。国际上对护理术语标准化的研究开始于上世纪七十年代,现已发展了多个标准化护理术语分类体系。到目前为止,根据术语的使用情况及影响程度,美国护士协会(American Nurses Association,ANA)主要认可了7个护理术语体系,本文就这些术语分类体系的特点、内容、结构及发展情况作一综述。
冠状动脉左主干异常开口于肺动脉一例

总之,ALCAPA临床少见,超声心动图是初筛的重要工具,异常扩张的右冠状动脉、丰富的室间隔血流频谱等超声心动图表现可间接提示ALCAPA,需要冠状动脉造影或多排CT冠状动脉成像来明确诊断。部分情况下因彩色溢出伪像导致错误判断左主干开口于主动脉,加上肺动脉可见舒张期倒灌血流频谱,临床易误诊为冠状动脉-肺动脉瘘,此时关注左主干内血流的多普勒信号方向有助于伪像识别,高度怀疑ALCAPA时应进一步行其他影像学检查来协助诊断。一旦诊断明确应尽早手术,术后长期预后良好。
红细胞分布宽度与心血管疾病的研究进展

红细胞(red blood cell, RBC)分布宽度(red blood cell distribution width, RDW)是对RBC异质性定量检测的一个客观指标,反映的是RBC体积变化的不均一性,通常用于贫血的鉴别诊断。近年来研究发现RDW与心血管事件相关,是各种急性和慢性心血管疾病强预测指标,也是独立预测心血管疾病预后的新指标。如RDW的变化是心力衰竭(心衰)患者治疗后长期预后不佳的强预测因素。其机制可能与RBC的可变形性相关,RDW增加,RBC的可变形性降低,使得微循环血流通过受损,进而导致缺氧,有助于解释RDW增加和心血管疾病间的相关性。
苦参碱联合高三尖杉酯碱对HL-60细胞凋亡的影响及其机制研究

近年来中药成分分子靶向治疗白血病成为国内外研究的热点,中药有效成分高三尖杉酯碱(HHT)、苦参碱(MAT)等经多种与化疗药物协同作用于白血病细胞已受到越来越广泛的重视,但MAT联合HHT治疗急性髓系白血病(AML)的报道极少。诱导细胞凋亡亦是中药抑制肿瘤细胞增殖的一条重要途径,我们通过探讨MAT联合HHT 对人AML细胞系HL-60细胞凋亡的影响及机制,为中药联合应用抗AML提供理论依据。
Impact of meteorological conditions on a nine-day particulate matter pollution event observed in December 2013, Shanghai, China

A severe particulate matter pollution event occurred in Shanghai from 1 to 9 December 2013. The mean hourly mass concentrations of PM_(2.5) and PM1_0 were 211.9 and 249.0 μg/m~3, respectively. Reanalysis data, in situ, and remote-sensing measurements were used to examine the impacts of meteorological conditions on this event. It was found that the synoptic pattern of weak pressure, the reduced planetary boundary layer height, and the passage of two cold fronts were key factors causing the event. Four stages were identified during this event based on the evolution of its PM_(2.5) levels and weather conditions. The highest concentration of PM_(2.5) (602 μg/m~3) was observed in stage 3. High PM_(2.5) concentrations were closely associated with a low local ventilation index, with an average of 505 m~2/s, as well as with the influx of pollutants from upstream, transported by the cold fronts.
Characterization of summer PM_(2.5) aerosols from four forest areas in Sichuan, SW China

Aerosol samples were collected over 24 and 12 h to represent day/night aerosol characteristics in forest areas at Ya'an Baima Spring Scenic Area (BM), Panzhihua Cycas National Nature Reserve (PZ), Gongga Mountain National Nature Reserve (GG), and Wolong National Nature Reserve (WL), during the summers of 2010-2012. Mass and chemical component concentrations, including organic carbon, elemental carbon, and inorganic ions (F~-, CI~-, NO_2~-, NO_3~-,SO_4~(2-), C_2O_4~(2-), PO_4~(3-),K~+, Na~+, Ca~(2+), Mg~(2+), and NH_4~+), of PM_(2.5) aerosols were measured. The average PM_(2.5) concentrations for 24 h were 72.42,104.89,20.55,and 29.19 μg/m~3 at BM, PZ, GG, and WL, respectively. Organic matter accounted for 38.0-49.3%, while elemental carbon accounted for 2.0-5.7% of PM_(2.5) mass. The sum concentrations of SO_4~(2-), NH_4~+, and NO_3~-accounted for 23.0%, 17.4%, 22.1%, and 30.5% of PM_(2.5) mass at BM, PZ, GG, and WL, respectively. Soil dust was also an important source of PM_(2.5), accounting for 6.3%, 17.0%, 10.4%, and 19.1% of PM_(2.5) mass at BM, PZ, GG, and WL, respectively. These reconstructed masses accounted for 75.9-102.0% of PM_(2.5) mass from the four forest areas of SW China.
Long-term trends in fog and boundary layer characteristics in Tianjin, China

Long-term trends in fog episodes, vertical variations of atmospheric boundary structure, and air pollutant concentrations during two different heavy fog events in the Tianjin area were analyzed. The total amount of fog has increased since 1980 due to the stability of the boundary layer and an increase of pollutant emissions. The variation in the characteristics of the boundary layer and air pollutant concentrations were significantly different between the two fog processes (fog I and fog II). The onset of fog I was accompanied by a temperature inversion in the low atmosphere, and the average kinetic energy showed a clear diurnal trend and vertical variation, which increased with height. The dissipation of fog I was mainly due to turbulence. However, the atmospheric stratification was not stable in the lower layer before the onset of fog II. The diurnal and vertical changes in kinetic energy were very small, in which turbulent momentum at each measurement height tended to be zero. In the dissipation process of fog II, wind speed increased significantly. Surface PM_(2.5) concentrations decreased, but the ratio of PM_(2.5) to PM_(10) increased from 0.66 to 0.82 until fog I dissipated. However, the concentration of PM_(2.5) did not decrease at the early stage of fog II, but the ratio of PM_(2.5) to PM_(10) PM_(2.5)/PM_(10) decreased to 0.21 when fog II dissipated. This study showed that there was a clear difference in the evolution of pollutant concentration for different pollutants and in different developing stages during the fog events. PM_(2.5) concentration accumulated faster than those of SO_2 and NO_x, and the PM_(2.5) cumulative rate was greater in the mid-term of the fog process.
Preparation and characterization of Pd/Fe bimetallic nanoparticles immobilized on Al_2O_3/PVDF membrane: Parameter optimization and dechlorination of dichloroacetic acid

Using a liquid-solid phase inversion method, a hybrid matrix poly(vinylidene fluoride) (PVDF) membrane was prepared with alumina (Al_2O_3) nanoparticle addition. Pd/Fe nanoparticles (NPs) were successfully immobilized on the Al_2O_3/PVDF membrane, which was characterized by Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM). The micrographs showed that the Pd/Fe NPs were dispersed homogeneously. Several important experimental parameters were optimized, including the mechanical properties, contact angle and surface area of Al_2O_3/PVDF composite membranes with different A1_2O_3 contents. At the same time, the ferrous ion concentration and the effect of hydrophilization were studied. The results showed that the modified Al_2O_3/PVDF membrane functioned well as a support. The Al_2O_3/PVDF membrane with immobilized Pd/Fe NPs exhibited high efficiency in terms of dichloroacetic acid (DCAA) dechlorination. Additionally, a reaction pathway for DCAA dechlorination by Pd/Fe NPs immobilized on the Al_2O_3/PVDF membrane system was proposed.
Synergistic effects of particulate matter (PM_(10)) and SO_2 on human non-small cell lung cancer A549 via ROS-mediated NF-κB activation

Since a real atmospheric scenario usually represents a system involving multiple pollutants, air pollution studies typically focused on describing adverse effects associated with exposure to individual pollutants cannot reflect actual health risk. Particulate matter (PMio) and sulfur dioxide (SO_2) are two major pollutants derived from coal combustion processes and co-existing in coal-smoke air pollution, but their potentially synergistic toxicity remains elusive thus far. In this study, we investigated the cytotoxic responses of PM_(10) and SO_2, singly and in binary mixtures, using human non-small cell lung cancer A549 cells, followed by clarifying the possible mechanisms for their interaction. The results indicated that the concomitant treatment of PM_(10) and SO_2 at low concentrations led to synergistic injury in terms of cell survival and apoptosis occurrence, while PM_(10) and SO_2 alone at the same concentrations did not cause damage to the cells. Also, radical oxygen species (ROS) production followed by nuclear factor kappa B (NF-κB) activation was involved in the above synergistic cytotoxicity, which was confirmed by the repression of the actions by an ROS inhibitor (NAC). This implies that assessment of health risk should consider the interactions between ambient PM and gaseous copollutants.
Microcystis aeruginosa/Pseudomonas pseudoalcaligenes interaction effects on off-flavors in algae/bacteria co-culture system under different temperatures

We conducted an experiment to study the interaction effects of Microcystis aeruginosa and Pseudomonas pseudoalcaligenes on off-flavors in an algae/bacteria co-culture system at three temperatures (24, 28 and 32。C). Gas chromatography-mass spectrometry was applied to measure off-flavor compounds dimethyl sulfide (DMS), dimethyl trisulfide (DMTS), 2-methylisoborneol, geosmin (GEO) and β-cyclocitral. During the lag phase of co-cultured M. aeruginosa (first 15 days), P. pseudoalcaligenes significantly increased the production of DMS, DMTS and β-cyclocitral at all three temperatures. In the exponential phase of co-cultured M. aeruginosa (after 15 days), M. aeruginosa became the main factor on off-flavors in the co-culture system, and β-cyclocitral turned to the highest off-flavor compound. These results also indicated that DMS, DMTS and β-cyclocitral were the main off-flavor compounds in our M. aeruginosa/P. pseudoalcaligenes co-culture system. Univariate analysis was applied to investigate the effects of M. aeruginosa and P. pseudoalcaligenes on the production of off-flavors. The results demonstrated that both M. aeruginosa and P. pseudoalcaligenes could increase the production of DMS and DMTS, while β-cyclocitral was mainly determined by M. aeruginosa. Our results also provide some insights into understanding the relationship between cyanobacteria and heterotrophic bacteria.
Sex determination in mammalian germ cells

Germ cells are the precursors of the sperm and oocytes and hence are critical for survival of the species. In mammals, they are specified during fetal life, migrate to the developing gonads and then undergo a critical period during which they are instructed, by the soma, to adopt the appropriate sexual fate. In a fetal ovary, germ cells enter meiosis and commit to oogenesis, whereas in a fetal testis, they avoid entry into meiosis and instead undergo mitotic arrest and mature toward spermatogenesis. Here, we discuss what we know so far about the regulation of sex-specific differentiation of germ cells, considering extrinsic molecular cues produced by somatic cells, as well as critical intrinsic changes within the germ cells. This review focuses almost exclusively on our understanding of these events in the mouse model.
异位胰腺的诊断与治疗

异位胰腺又称为迷走胰腺或副胰腺,是正常胰腺部位以外孤立的胰腺组织,拥有独立的血液供应和神经支配,和正常胰腺间无任何解剖、血管关系,是一种先天畸形,可发生在消化道及消化道外的部位。我们回顾性分析了从1999年9月至2013年8月间收治的诊断为异位胰腺的39例病例,现总结报道如下。
Simulated Heat Sink in the Southern Ocean and Its Contribution to the Recent Hiatus Decade

A set of numerical experiments is designed and carried out to understand a heat sink in the Southern Ocean in the recent hiatus decade. By using an oceanic general circulation model, the authors focus on the contributions from two types of forcing: wind stress and thermohaline forcing. The simulated results show that the heat sink in the upper Southern Ocean comes mainly from thermohaline forcing; while in the deeper layers, wind stress forcing also plays an important role. These different contributions may be due to different physical processes for the heat budget. The combination of these two types of forcing shows a significant heat sink in the Southern Ocean in the recent hiatus decade, and this is consistent with the observations and conclusions of a similar recently published study.
The Relationship between the Interdecadal Variation of Summer Precipitation and Its Interannual Variability over the Middle and Lower Reaches of the Yangtze River Valley

The intensity of summer precipitation interannual variability is strongest over the middle and lower reaches of the Yangtze River Valley (MLYRV). The variability is larger than 1.5 mm d-1 and up to 35%-40% of the climatological mean summer precipitation. The relationship between the interdecadal change in the intensity of summer precipitation and its interannual variability over this area is investigated, by analyzing five gauged and re-constructed precipitation datasets. The relationship is found to be very weak over the MLYRV, with a correlation coefficient of only approximately 0.10. The Pacific Decadal Oscillation influences the western North Pacific subtropical high, which is responsible for the interdecadal change in summer precipitation over the MLYRV. However, the precipitation interannual variability is closely related to the ENSO events in the preceding winter due to its impact on the meridional displacement of the East Asian westerly jet. Different physical mechanisms cause different interdecadal variation in the intensity of summer precipitation and its interannual variability, and thus result in a poor relationship.
Interannual Climate Variability of the Past Millennium from Simulations

The interannual variability of global temperature and precipitation during the last millennium is analyzed using the results of ten coupled climate models participating in the Paleoclimate Modelling Intercomparison Project Phase 3. It is found that large temperature (precipitation) variability is most dominant at high latitudes (tropical monsoon regions), and the seasonal magnitudes are greater than the annual mean. Significant multi-decadal-scale changes exist throughout the whole period for the zonal mean of both temperature and precipitation variability, while their long-term trends are indistinctive. The volcanic forcings correlate well with the temperature variability at midlatitudes, indicating possible leading drivers for the interannual time scale climate change.
Vitamin D Receptor (VDR) Genetic Polymorphisms Associated with Intervertebral Disc Degeneration

Intervertebral disc degeneration (IDD) is characterized by disc dehydration and herniation, which is often associated with low back pain and lumbar radiculopathy due to nerve root compression or inflammation. The pathophysiology of IDD is not completely elucidated so far. Some researchers have indicated that disc degeneration begins as early as the second decade of life (Mayer et al., 2013). Common risk factors are considered to associate with age, gender, smoking history,occupation, disc injury, and biomechanical factors. However,some epidemiologic studies highlighted that disc degeneration may be caused to a large degree by hereditary factors with apparently a relatively minor effects of environmental and behavioral risk factors (Videman et al., 1998; Cheung et al.,2006; Eser et al., 2010; Mayer et al., 2013; Vieira et al.,2014), which indicated that genetic factors might play an important role in the pathogenesis of IDD.
One SNP in COLD1 Determines Cold Tolerance during Rice Domestication

With the effect of global climate change on grain yield and distribution of crops, to understand how plant responds to extreme temperature stress is becoming crucial. Plants have evolved fine-tuned mechanisms in response to a wide variety of environmental stresses. During rice (Oryza sativa L.)domestication, two main genotypes are bred and extendedly cultivated in the tropical and subtropical areas in the world:indica (O. sativa ssp. indica) is sensitive to low temperature and mainly cultivated in tropical areas in higher yearly temperature; whereas japonica (O. sativa ssp. japonica) is tolerant to low temperature and mainly cultivated in subtropical areas in lower yearly temperature. The chilling sensitivity and resistance of rice cultivars are derived from ancestral Chinese wild rice during rice domestication. Previous studies have indicated that cold tolerance trait of subtropical cultivars is controlled by quantitative trait loci (QTLs) (Miura et al.,2011). However, the molecular basis for these QTLs has not been well studied. A recent study from Kang Chong’s lab at Institute of Botany, Chinese Academy of Sciences (http://www.ibcas.ac.cn/) has successfully identified a rice gene named chilling-tolerance-divergence1 (COLD1) that may function as a pivotal cold sensor through modulating Ca~(2+) signaling to confer cold tolerance (Ma et al., 2015).
高血压个体化诊治中立卧位血压测量的价值

总之,为了做到个体化、优化的治疗,立、卧位血压的测量是必不可少的一项措施。实际上,一些高血压患者虽然坐位血压达标,但立位或卧位血压仍然过高,只是医生没有重视而已。
轴聚角与全冠固位的相关性研究

全冠的固位力主要是摩擦力和粘结力,摩擦力则与轴聚角和(牙合)龈高度有关。轴聚角在全冠固位因素中,虽不是主要的,但它对全冠的固位却不容小觑。因轴聚角是一假想角,以前仅限于理论层面研究。笔者认为轴聚角的制作有不足之处,轴聚角的度数是否合理有待商榷。本研究通过数学计算,使轴聚角度数真实存在,从而更直观的分析轴聚角大小与全冠固位的相关性,为临床基牙预备提供参考。
瘦素与自身免疫细胞的作用研究新进展

瘦素(leptin)是一种主要由脂肪组织合成、分泌的多肽激素,在调节摄食、体质量、能量平衡中发挥作用,也能影响生殖、免疫、造血、骨代谢、内分泌系统及血管再生等多方面的生理功能。瘦素在调节免疫反应的作用已经获得体外评估并已进入相关信号通路的临床研究,免疫介导性疾病在瘦素分泌增加的影响下将产生相关的促炎致病因子。因此,瘦素已经成为一种炎症反应的中介。本文就近年来瘦素与自身免疫细胞的作用研究进展作一综述。
粒-巨噬细胞集落刺激因子及其受体拮抗剂mavrilimumab在类风湿关节炎中研究进展

RA是一种系统性慢性自身免疫性疾病,以持续侵蚀性的炎症性多关节炎为主要临床表现,除关节外,也可累及肺、心脏、皮肤等其他脏器,如果没有得到合理的治疗,将导致关节毁损和瘫痪,生活质量下降和寿命缩短。粒-巨噬细胞集落刺激因子(granulocyte-macrophage colony stimulating factor, GM-CSF)是一种具有多效性的造血细胞生长因子,在粒细胞系与巨噬细胞系的发育与成熟的各阶段起到调控作用。近年研究表明GM-CSF在炎症反应与自身免疫疾病中有重要作用,GM-CSF参与RA发病,而其受体拮抗剂mavrilimumab能够拮抗GM-CSF信号传导,显著改善关节炎小鼠的症状。为此,本文将综述GM-CSF及其受体拮抗剂mavrilimumab在RA治疗中的研究进展。
右眼眶滑膜肉瘤1例

滑膜肉瘤是一种恶性程度较高的软组织恶性肿瘤,它并不来源于滑膜或向滑膜方向分化,而是一种形态、临床、遗传学上独特的病变,可以发生在任何部位,80%以上起源于近关节处深部软组织,发生于眼眶者极为少见。该病无特定发病年龄,但好发于青年人,以男性多见。临床上常表现为可触及的无痛性软组织肿块,一般不引起明显的功能障碍,少数有疼痛及毗邻关节的功能障碍。