mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
塔里木、四川及鄂尔多斯盆地白云岩储层孔隙成因探讨及对储层预测的指导意义

以塔里木、四川和鄂尔多斯盆地蒸发潮坪白云岩储层、蒸发台地白云岩储层、埋藏白云岩储层和热液白云岩储层为例,系统阐述了白云岩储层储集空间的成因,指出原岩(石灰岩)特征和各种溶蚀作用主导白云岩储层储集空间的发育,并不是传统观点所认为的白云石化是重要的孔隙建造作用.蒸发潮坪白云岩储层的孔隙形成于表生期大气淡水对膏云岩中石膏及未云化灰质的溶蚀;蒸发台地白云岩储层的孔隙形成于表生期大气淡水对石膏及未云化文石或高镁方解石颗粒的溶蚀;埋藏白云岩储层的孔隙主要是对原岩孔隙的继承和调整,埋藏溶蚀作用对孔隙建造有一定的贡献;热液白云岩储层晶间孔可能形成于热液白云石化作用或是对原岩孔隙的继承和调整,晶间溶孔和溶洞形成于热液溶蚀作用.白云岩的分布与白云岩储层的分布不完全吻合,白云石化作用总能形成白云岩,但不一定是白云岩储层.蒸发潮坪白云岩储层侧向上分布于蒸发潮坪膏云岩带,带状或准层状分布,受相带控制,垂向上分布于向上变浅的蒸发潮坪旋回顶部(层序界面之下)的膏云岩中,多套叠置.蒸发台地白云岩储层侧向上分布于蒸发台地(盐湖)周缘及膏盐层之下,环带状及层状分布,受相带控制,垂向上分布于向上变浅旋回顶部(层序界面之下)的礁滩相白云岩、膏云岩中,多套叠置.埋藏白云岩储层侧向上分布于台缘或台内白云石化(交代或重结晶)的多孔礁滩相沉积中,受相带控制,垂向上分布于向上变浅旋回顶部(层序界面之下)的晶粒白云岩中,多套叠置.热液白云岩储层沿断裂、不整合面等热液通道呈准层状、透镜状分布.
中国高层大气与电离层耦合研究进展

近年来,地球高层大气与电离层之间的耦合研究为众多学者所关注.在回顾这一领域国际上若干研究方向进展的基础上,着重介绍了中国学者的近期研究工作与贡献.首先,扼要介绍了中国高层大气观测的新发展,包括激光雷达、FP干涉仪、全天空气辉成像仪等光学探测,MST雷达、全天空流星雷达等无线电探测手段.在高层大气变化特性研究中,介绍了高层大气的气候学及各种大气波动的研究进展.在高层大气与低电离层的耦合研究方面,介绍了突发钠层及低热层钠层的观测研究和钠层模式的研究进展,以及突发E层与大气行星波之间的耦合研究工作.在高层大气波动过程与电离层F2层耦合研究中,着重介绍了电离层四波经度结构与高层大气非迁移潮汐之间的耦合特性与机理研究.在热层与电离层耦合的研究方向上,介绍了热层背景大气风场和重力波对电离层的作用、带电粒子对赤道热层的影响与热层赤道异常的形成机理研究等热层电离层相互耦合工作.综合认为,近年来中国学者在高层大气与电离层耦合的研究领域进行了大量工作,包括实验观测及数据分析、模式化与理论研究等.中国学者取得的研究成果为这一领域近年来的进展与突破做出了重要贡献.
温度刺激与肠易激综合征的研究进展

IBS 是以慢性腹部不适,伴有排便性质改变为特征的临床综合征,是较为常见的胃肠道功能性疾病之一。全球有7%~10%的人群深受 IBS 的困扰。虽然 IBS 的发生及其机制尚未明确,但已有研究表明,IBS 的发生可能与胃肠道动力异常、内脏高敏感、精神心理异常、肠黏膜免疫功能异常及遗传等因素有关。流行病学研究显示,IBS 患者在进冷食和受寒后容易诱发或加重腹部症状。国内有学者认为此现象在我国较为多见。同时,温度敏感性受体的发现,为探究 IBS 患者对温度敏感性增高提供了新的思路。本研究就温度刺激与 IBS 关系的研究进展综述如下。
达芬奇机器人三维立体微创技术在结直肠外科中的应用与评价

结直肠癌(colorectal cancer)在发达国家是较常见的恶性肿瘤之一,在我国,其发病率与病死率呈逐年攀升态势。结直肠癌的治疗方面,目前仍提倡以手术为主的综合治疗,包括手术、化学疗法和放射疗法等。手术可选择传统开放术式和腹腔镜等微创手术,其中单孔腹腔镜手术(single incision laparoscopic surgery,SILS)、经自然腔道内镜手术(natural orifice transluminal endoscopic surgery,NOTES)和机器人辅助腹腔镜手术(robotic surgery)是目前微创技术所能达到的最高点。自2002年美国 FDA 批准的达芬奇机器人手术系统完成第1例机器人结直肠癌手术起,它在这一领域的应用逐渐增多。研究表明,与传统开放手术相比,达芬奇机器人手术是一种安全、有效的方法,特别适用于在骨盆等狭小的空间内进行解剖操作。尽管关于机器人的手术研究已开展很多,但对于患者近期生理功能的恢复及远期肿瘤预后的影响仍有待大样本的随机对照研究的结果。
甲板替代物覆盖游离断层甲床修复甲床缺损的临床分析

2011年2月至2013年8月,我科共收治22例28指甲床缺损患者,其中10例11指采用输液管壶半管原位缝合固定技术结合伤指游离断层甲床瓣修复甲床缺损,还使甲床在甲板替代物的保护下平整生长愈合,避免换药时因传统凡士林纱布包扎粘连导致的疼痛,又保持了伤指形态、功能的健全,技术简单,疗效满意,预后良好。
逆行邻趾趾底动脉背侧皮支皮瓣修复(左足右母)甲皮瓣供区

自Morrison于1980年首先报告(左足右母)甲皮瓣移植再造拇指以来,(左足右母)甲皮瓣得到了广泛应用。其优点是外形接近于正常拇指,而且供足不减少趾数。对于皮瓣供区,常规采用将(左足右母)趾趾端部分趾骨咬除,用(左足右母)趾胫侧遗留的皮瓣覆盖骨残端,再取中厚皮片移植的方法来修复,由此带来(左足右母)趾部分短缩及植皮易坏死,形成长期不愈合创面的弊端。2009年10月至2013年2月,我院采用逆行邻趾趾底动脉背侧皮支皮瓣转位覆盖骨性创区,配合局部全厚皮片植皮的方法修复(左足右母)甲皮瓣供区13例,在不短缩(左足右母)趾长度的同时完成对供区创面的一期修复,取得了较好的治疗效果。
Zircon U-Pb SHRIMP Ages from the Late Paleozoic Turpan-Hami Basin, NW China

Permian volcanic rocks are widely distributed in the Turpan-Hami Basin, which is part of the Central Asian orogenic belt. Here we present SHRIMP zircon data for the rhyolite in Well Baocan 1, one of the deepest wells in the basin. The 283.9±2.7 Ma reported in our study provides the best precise age determination for the Yierxitu Formation, the oldest Permian layer of Hami Depression, one of the three substructural units of the Turpan-Hami Basin, and a potential hydrocarbon reservoir in this ba-sin. Our data refines earlier imprecise~(39)Ar-~(40)Ar ages and shows that the volcanic rocks both inside the Turpan-Hami Basin and along its margin are almost coeval. We delineate a collisional orogenesis, and the new age of 283.9±2.7 Ma may limit the latest time of the collision orogenesis.
Sequence Stratigraphy and Sedimentary Facies of Lower Oligocene Yacheng Formation in Deepwater Area of Qiongdongnan Basin, Northern South China Sea: Implications for Coal-Bearing Source Rocks

For unveiling coal-bearing source rocks in terrestrial-marine transitional sequences, the sequence stratigraphic framework and sedimentary facies of Lower Oligocene Yacheng Formation of Qiongdongnan Basin were investigated using seismic profiles, complemented by well bores and cores. Three third-order sequences are identified on the basis of unconformities on basin margins and correlative conformities in the basin center, namely SQYC3, SQYC2 and SQYC1 from bottom to top. Coal measure in Yacheng Formation of Qiongdongnan Basin were deposited within a range of facies associations from delta plain/tidal zone to neritic sea, and three types of favourable sedimentary facies associations for coal measure were established within the sequence stratigraphic framework, including braided delta plain and alluvial fan, lagoon and tidal flat, and fan delta and coastal plain facies associations. Results shown that, in the third-order sequences, coal accumulation in landward areas (such as delta plain) of the study area predominantly correlates with the early transgressive systems tract (TST) to middle highstand systems tract (HST), while in seaward areas (such as tidal flat-lagoon) it correlates with the early TST and middle HST. The most potential coal-bearing source rocks formed where the accommodation creation rate (Ra) and the peat-accumulation rate (Rp) could reach a state of balance, which varied among different sedimentary settings. Furthermore, intense tectonic subsidence and frequent alternative marine-continental changes of Yacheng Formation during the middle rift stage were the main reasons why the coal beds shown the characteristics of multi-beds, thin single-bed, and rapidly lateral changes. The proposed sedimentary facies associations may aid in predicting distribution of coal-bearing source rocks. This study also demonstrates that controlling factors analysis using sequence stratigraphy and sedimentology may serve as an effective approach for coal-bearing characteristics in the lower exploration deepwater area of South China Sea.
Geochronology and Geochemistry of Middle-Late Ordovician Granites and Gabbros in the Erguna Region, NE China:Implications for the Tectonic Evolution of the Erguna Massif

Zircon U-Pb ages, Hf isotope data and whole-rock major and trace element data for the Middle to Late Ordovician gabbros and granites in the Erguna Massif, NE China were presented in this paper. The petrogenesis of these rocks and the Early Paleozoic tectonic evolution of the massif were discussed. Zircons from the granites and gabbros are of magmatic origin based on their cathodolumi-nescence (CL) images. The ~(206)Pb/~(238)U ages obtained from 20 spots on zircons from the granites range from 446±9 to 464±10 Ma, yielding a weighted mean age of 455±10 Ma; and 16 spots on zircons from the gabbros range from 465±10 to 466±7 Ma, yielding a weighted mean age of 465±2 Ma. Chemically, the Late Ordovician granites in the Erguna Massif are weakly peraluminous and similar to A-type granites. The granites and gabbros are all enriched in light rare earth elements and large ion lithophile elements (e.g., Rb, K), and depleted in heavy rare earth elements and high field strength elements (e.g., Nb, Ta, and Ti); they all exhibit marked negative Eu anomalies. Their zircon ε_(Hf)(t) values range mainly from +1.86 to +6.21 (for the granites) and +1.39 to +3.89 (for the gabbros), except for one spot with a value of -0.27 (for a gabbro). TheTDM1 ages for the gabbros and T_(DM2) ages for the granites vary from 928 to 1 091 Ma and from 1 287 to 1 675 Ma, respectively. It is concluded that the primary magma of the granites could have been derived by partial melting of Mesoproterozoic newly accreted crustal ma-terial, whereas the primary magma of the gabbros originated by partial melting of a depleted mantle wedge that had been metasomatized by fluids derived from a subducted slab. These Middle-Late Or-dovician granites and gabbros constitute a typical bimodal igneous rock association, implying an exten-sional environment that was probably related to the post-collisional development of the Erguna and Xing’an massifs in the early Early Paleozoic.
Conodont Biostratigraphy across the Permian-Triassic Boundary at the Xinmin Section, Guizhou, South China

A continuous sedimentation at the Xinmin Section, Anshun, Guihzou Province, with the Upper Permian Talung Formation dominated by bedded siliceous rocks, and the Lower Triassic Luo-lou Formation consisting mudstones and marls as well as siliceous mudstones at its basal part indicates that it represents a deeper-water basinal facies across the Permian-Triassic boundary. Based on a sys-tematic conodont biostratigraphic work, nine conodont species belong to two genera have been identi-fied in this study. It enable us to establish five conodont zones at this section, in ascending order, they are:Clarkina changxingensisZone (beds 1-3-4-2),Clarkina yini Zone (beds 4-3-5-1-1),Clarkina me-ishanensis Zone (beds 5-1-2-5-2),Hindeodus changxingensis Zone (beds 5-3-1-5-3-2) andHindeodus parvus Zone (beds 5-3-3-5-3-4), respectively. According to the first occurrence ofHindeodus parvusin bed 5-3-3, the Permian-Triassic boundary is placed at the base of bed 5-3-3. This conodont zonation of the Xinmin Section provides precise biostratigraphic framework for further investigations on the geo-logical events across the Permian-Triassic boundary at this section. In addition, the new conodont data also reveals that several siliceous beds occurred at the basal Triassic. It provides an exception of Early Triassic Chert Gap.
Using acupoint-to-acupoint penetrative needling to treat poststroke spastic paralysis: a clinical progress review

OBJECTIVE: To determine the characteristics and advantages of acupoint-to-acupoint penetrative needling (AAPN) treatment for post-stroke spastic paralysis (PSSP) to improve the clinical outcomes of this disease in the future. METHODS: Randomized, controlled trials of PSSP patients receiving AAPN treatment were searched from MEDLINE, EMBASE, and China National Knowledge Infrastructure Database between January 2006 and June 2013. Key words included: clinic or clinical, acupuncture, needling, acupoint-to-acupoint, penetrative or penetration or penetrating, stroke or apoplexy or cerebral infarction or cerebral hemorrhage, spastic paralysis or spasticity or palsy, and hypermyotonia. Language was limited to English and Chinese. Case series reports, review articles, and animal studies were excluded. RESULTS: AAPN showed better clinical results on PSSP than other acupuncture treatments, especially when combined with adjunct therapies such as electroacupuncture, bloodletting, and rehabilitation. The greatest benefit was achieved with rehabilitation combined with penetration from Yang-channel acupoints to Yin-channel acupoints in the upper limbs, and from Yin-channel acupoints to Yang-channel acupoints in the lower limbs with a reinforcing maneuver. CONCLUSION: AAPN is an effective treatment for PSSP, and it can accelerate and enhance functional repair of PSSP patients.
Use of Xinfeng capsule to treat abarticular pathologic changes in patients with rheumatoid arthritis

OBJECTIVE: To observe the influence of Xinfeng-capsule (XFC) on abarticular pathologic changes (APCs) and other indices of patients with rheumatoid arthritis (RA) and explore the mechanism of action of XFC in improving such changes. METHODS: Three-hundred RA patients were divided randomly into a treatment group (n=150) and control group (n=150). A normal control (NC) group (n=90) was also created. Changes in cardiac function, pulmonary function, anemia indices and platelet parameters of RA patients were measured. Curative effects of the two groups were compared, and comparison carried out with the NC group. RESULTS: In 300 RA patients, late diastolic peak flow velocity (A peak) was much higher (P<0.01) and early diastolic peak flow velocity (E peak), E/A, and left ventricular fraction shortening much lower (P<0.01) than those in the NC group. Vital capacity (VC), forced vital capacity in one second, forced vital capacity (FVC), maximal voluntary ventilation (MW), maximal expiratory flow in 50% of VC (FEF50) and FEF75 were lowered remarkably (P< 0.05 or P<0.01). Platelet count (PLT), plateletcrit (PCT) and mean platelet volume (MPV) increased markedly (P<0.05 or P<0.01), and hemoglobin (Hb) level decreased significantly (P<0.05). After XFC treatment, the A peak and PLT and PCT were much lower (P<0.05), and E/A and the number of red blood cells as well as Hb level were much higher (P< 0.05), as were FVC, MW and FEF50 (P<0.05 or P< 0.01), in the treatment group than those in the NC group. Total score of pain and swelling in joints, uric-acid level and high-sensitivity C-reactive protein level were much lower, and superoxide dismutase level as well as the number of CD4 + CD25+ regulation T cells (Treg) and CD4+CD25 + CD127-Treg were much higher (P<0.05 or P<0.01) in the treatment group than those in the NC group. CONCLUSION: RA patients with pathologic changes in joints also suffer from lower cardiac and pulmonary functions and from parameters of anemia and platelet factors. XFC can improve the symptoms of RA patients, ameliorate their cardiac and pulmonary functions and reduce the parameters of anemia and platelet factors. XFC lowers the immune inflammatory reaction to improve APCs in RA patients.
乳腺颗粒细胞瘤MR影像一例

讨论本病例MR显示肿块呈大致均匀强化,呈平台型动态强化曲线,与多数文献报道相符。本病例肿块内部ADC值较低为1.01 x 10~(-3) mm~2/s,但周边ADC值为1. 26 X 10~(-3)mm~2/s,与恶性肿瘤区分有一定鉴别意义。尽管GCT 有一定的影像特征,但因其发病率少,医生诊断经验不足及肿瘤的一些恶性特征,在临床、放射学和大体形态上易误诊为乳腺癌。针吸细胞学及术中冰冻病理检查也较难诊断,术后病理仍是目前唯一的确诊方法。
Biosafety legislation and the use of GM crops in Brazil

Thirty-eight GM crop events are currently approved for commercial use in Brazil, where their intrinsic characteristics include herbicide, insect and virus resistance. The Brazilian Biosafety Law establishes guidelines for the safe use of genetic engineering technologies in research and product development for the market. The Law created a structure with collegiate and governmental agencies for the establishment of biosafety guidelines, risk assessment and official inspections. It created the National Biosafety Council (CNBS) and restructured the National Biosafety Technical Commission (CTNBio). The CTNBio is responsible for establishing the biosafety guidelines and to issue the Biosafety Quality Certificate (CQB) for all institutions working with GMO. The Brazilian Biosafety Law considers an infringement of the legislation any action or omission that violates the norms provided by it. Many sanctions can be applied where the Registration and Inspection agencies (OERF) define criteria, fine amounts and collect it for the federal government. Other important Brazilian legislation regarding GMO use in Brazil is the Law n° 8 078 which establishes the right to information for all consumers in the country. Through this Law, Brazilian Ministry of Justice defined a labeling system whereby foods and food ingredients for human consumption or animal feed containing or produced with more than 1% GMO must contain information on its label and a symbol (a yellow triangle with a T in the middle) indicating it. It is undeniable that there was a rapid increase in the utilization of genetic engineering technologies in the Brazilian agriculture after the new Biosafety Law. The unification of laws, rules and guidelines by all agencies involved in the Biosafety legislation framework allowed, undoubtedly, the rescue of the confidence by investors, researchers, private/ public institutions and by all other stakeholders involved in the Brazilian agribusiness.
Demands for green technologies in future plant breeding

Many issues need to be dealt with for future plant breeding. In this paper, I briefly discussed issues related to the concept of food security from the perspective of total demand both in quantity and quality and production sustainability. We are now facing great challenges in both demand and sustainability. Food production needs to be greatly increased in the coming decades to cope with the population explosion, while the environmental sustainability requires reduction of input including chemical fertilizers, pesticides, water, labor and other resources. Increased awareness of the relation between nutrition and health also requires crop products to better meet the need of human population by producing more nutritious food. The goals and directions of plant breeding have to evolve accordingly to address all these needs. To this end, I briefly reviewed the recent progress in plant genomic research and technology development and discussed how these advances can be applied to breeding programs to address food security issues.
单纯性汗腺棘皮瘤1例

单纯性汗腺棘皮瘤(hidroacanthoma simplex,HS),是一种临床上较少见的良性皮肤附属器肿瘤,起源于末端汗管。本病由Coburn和Smith于1956年首次报告,国内目前报道较少。1990年,Abenoza和Ackerman提出单纯性汗腺棘皮瘤、小汗腺汗孔瘤、真皮内导管瘤及汗孔汗腺瘤等4种肿瘤是良性汗孔肿瘤的变异型,可统称为汗孔瘤。当瘤体完全局限于表皮内,称为单纯性汗腺棘皮瘤。HS多见于老年人,发病无性别差异。皮损好发于肢体远端,也可发生于胸部、上臂和面部,表现为角化性红斑或棕色斑块[3]。其大小不一,最大者可达8.0 cmx9.0 cm。本病易与鲍恩病及克隆型脂溢性角化相混淆。鲍恩病组织病理主要表现为表皮细胞排列不规则,细胞大而圆,胞质呈均质性强嗜酸性,核染色质深,表皮基膜完整;有非典型性和角化不良,无明显的导管分化,很少表现为表皮内巢状改变。克隆型脂溢性角化组织病理虽然也可在表皮内形成巢状肿瘤团块,但细胞为鳞状细胞,与周围的角质形成细胞类似,细胞之间有间桥,连接紧密,有时形成鳞状窝。HS组织病理表现为表皮内境界清楚的肿瘤细胞巢,肿瘤细胞间可有细胞间桥、角珠,但瘤细胞无明显异形性,与周围的细胞分界明显,基膜尚正常。真皮浅层见有少许炎性细胞浸润。
Geochemical characteristics of Holocene sediments from Chuadanga district, Bangladesh: Implications for weathering, climate, redox conditions, provenance and tectonic setting

The present research deals with the geochemical characteristics of the Holocene sediments from Alam-danga area, Chuadanga district, Bangladesh. Main goals of the study are to delineate source rock characteristics, degree of chemical weathering and sorting processes and behavior of redox conditions during deposition of the sediments. Geochemical characteristics of the sediments show comparatively a wide variation in accordance with stratigraphy in their major element contents (e.g. SiO_2 69.46-82.13, Al_2O_3 2.28-8.88 in wt%), reflecting the distinctive provenance and in part an unstable period in terms of tectonic activity. Geochemical classification of the sediments shows mostly sub-arkose with few sub-litharenites. Some major and trace elements display comprehensible correlation with A1203 confirming their possible hydraulic fractionation. The chemical index of alteration (CIA*), W* index, index of compositional variability (ICV), plagioclase index of alteration (PIA*) values and the ratio of SiO_2/Al_2O_3, suggest low degrees of chemical weathering in the source areas as well as immature to moderately mature the sediments. The sediments suggest semi-arid climatic trends within oxic deltaic depositional conditions during the Holocene, at 3-12 ka. Whole rock geochemistry and discrimination diagrams demonstrate the continental signature derivatives, which might have been derived from the felsic to intermediate igneous rocks (granitic plutonic rocks) as well as from quartzose sedimentary/metamorphic provenance. These typical sources are present in a vast region of the Himalayan belt and catchment areas of Ganges. The tectonic setting of the sediments demarcates typically passive margin with slightly continental arc system.
新型沉淀分子印迹聚合物的制备及其在丹参血清药物化学研究中的应用

目的:应用分子印迹技术分离检测丹参在血清中的代谢组分。方法:采用沉淀聚合法,以丹参酮Ⅱ_A为模板分子,乙二醇二甲基丙烯酸酯(EGDMA)为交联剂,偶氮二异丁腈(AIBN)为引发剂,合成丹参酮Ⅱ_A分子印迹聚合物。用透射电子显微镜对丹参酮Ⅱ_A分子印迹聚合物的结构、形貌进行表征;并进行吸附性试验和选择性试验研究。结果:合成的分子印迹聚合物为规则的球形,约3 h达到吸附平衡,最大吸附量为34.09 μmol/g,并通过试验证明聚合物对丹参酮Ⅱ_A具有选择性能。结论:通过分子印迹固相萃取法(MIP-SPE)与HPLC-MS联用,实现高效的分离、灵敏的检测和全面的鉴定丹参药材中多种成分及其在大鼠血清中的代谢产物。
On the maximal eccentric connectivity indices of graphs

For a connected simple graph G, the eccentricity ec(v) of a vertex v in G is the distance from v to a vertex farthest from v, and d(v) denotes the degree of a vertex v. The eccentric connectivity index of G, denoted by ξ~c(G), is defined as ∑_(v∈V(G))d(v)ec(v). In this paper, we will determine the graphs with maximal eccentric connectivity index among the connected graphs with n vertices and m edges(n ≤ m ≤ n + 4), and propose a conjecture on the graphs with maximal eccentric connectivity index among the connected graphs with n vertices and m edges(m ≥ n + 5).
Dirichlet characters, Gauss sums and arithmetic Fourier transforms

In this paper, a general algorithm for the computation of the Fourier coefficients of 2π-periodic(continuous) functions is developed based on Dirichlet characters, Gauss sums and the generalized Mobius transform. It permits the direct extraction of the Fourier cosine and sine coefficients. Three special cases of our algorithm are presented. A VLSI architecture is presented and the error estimates are given.
经皮经肝穿刺肝内门体分流术联合胃冠状静脉栓塞治疗门静脉高压的临床分析

经颈静脉肝内门体分流术(TIPS)联合胃冠状静脉栓塞作为治疗门静脉高压及其并发症的重要方法已在临床广泛应用,并且疗效确切。然而,在一些特殊情况下,如严重肝硬化导致肝脏明显变形、各种原因导致门静脉海绵样变等,经颈静脉入路的常规TIPS常难以完成或导致手术失败。而经皮经肝穿刺至肝内门静脉后,经门静脉逆向穿刺肝静脉或下腔静脉切实可行。我院2009年5月至2012年5月对15例肝硬化食管胃底静脉曲张患者行经皮经肝穿刺肝内门体分流术(PTIPS)联合胃冠状静脉TH胶栓塞术治疗,取得成功并获得良好的效果,现报道如下。
多层螺旋CT血管成像技术在15例下肢深度冻伤患者中的应用

内蒙古自治区地处我国北方,由寒冷引起的组织损伤是冬季常见病,多见于野外作业、醉酒、迷路及精神失常者,严重的冻伤给人体的生命安全带来极大威胁。多层螺旋CT 血管成像(MSCTA)技术已成为临床普遍采用的影像学检查手段,但在冻伤方面的研究国内外尚鲜见报道。笔者将该技术应用于下肢深度冻伤救治中,为临床诊断提供依据。
成人带状疱疹误诊一例

从本病例的救治中,笔者总结出如下教训:(1)对于可疑病例,询问病史要仔细,详细询问受伤经过以及伤前有无感冒、发烧等前驱症状,不要被患者的主观叙述误导;(2)检查创面要细致,特别是水疱的形状、分布特征以及水疱液的性质;(3)夜间应在采光好的房间检查创面,照明灯亮度适中,防止光线过暗影响对创面特征的判断。
高压氧综合治疗24例胸椎骨折术后患者的疗效观察

脊髓损伤后肢体功能恢复是重症脊髓损伤困扰临床的一大难题。高压氧是否能改善患者临床症状报道较少。自2004年3月以来,笔者对24例胸椎骨折脊髓损伤术后偏瘫患者采用高压氧综合治疗,疗效满意。现报道如下。
重庆市三级医院信息化建设水平调查研究

目的:通过调查重庆市三级医院信息系统中与临床密切关联的模块上线情况,对重庆市三级医院信息化建设的特点及存在的问题进行分析。方法采用典型调查方法,对重庆市14所三级医院进行调查,通过当面访谈、网络调查的方式获取数据。结果重庆市三级医院信息化建设呈现较好的态势,门诊诊疗模块、住院诊疗模块和辅助检查模块等基础模块的上线率较高,但一些新兴的子模块如移动医护系统、医学专家决策支持系统的应用率较低。结论重庆市三级医院的信息化建设应结合医院自身的特点及发展需求进行,并应注重信息资源的整合与共享,带动二级医院的信息化建设。
Identification of biochemical association of phycobilisome with photosystems in cyanobacterial state transition

State transition is a short-term balance mechanism of energy distribution between photosystem II (PSII) and PSI. Although light-induced state transition in cyanobacteria has been suggested to depend completely on the phycobilisome (PBS) movement between PSII and PSI, the biochemical evidence has not been clearly shown. In this study, we locked the association of PBS with PSII or PSI using glycinebetaine when cells attain State 1 or 2 by exposure to light of blue or green, respectively. Subsequently, the PBS-reaction centers were resolved by blue native poly-acrylamide gel electrophoresis and two-dimensional electrophoresis, and then identified by western blot analysis. The results showed that in wild-type (WT) Synechocystis sp. strain PCC 6803, the PBS core always co-migrates with the PSII dimer during light-induced State 1-State 2 transition, but its rod leaves the PSII dimer in State 2 regardless of its co-migration in State 1. In the light-induced State 2, the co-migration of PBS rod with PSI trimer was observed in WT, but not in AndhB (M55), a State-2-transition-deficient mutant. This study first provided the biochemical evidence for the association of PBS with photosystems during cyanobacterial state transition.
Endoplasmic reticulum oxidoreductin 1α mediates hepatic endoplasmic reticulum stress in homocysteine-induced atherosclerosis

Endoplasmic reticulum (ER) stress is emerging as an important modulator of different pathological process and as a mechanism contributing to homocysteine (Hcy)-induced hepar injury. However, the molecular event that Hcy-induced ER stress in the hepar under the atherosclerosis background is currently unknown. Endoplasmic reticulum oxidoreductin 1α (ERO1α) plays a crucial role in maintaining ER stress function. In this study, we determined the expression of ERO1α in the hepar in hyperhomocysteinemia and the effect of ERO1α in hepacytes ER stress in the presence of Hcy. HHcy model was established by feeding the methionine diet in apolipoprotein-E-deficient (ApoE-/-) mice, and the hepatocytes were incubated with folate and different concentrations of Hcy. Our results showed that Hey triggered ER stress characterized by an increased contents of glucose-regulated protein 78 (GRP78), protein kinase RNA-like ER kinase (PERK), activating transcription factor (ATF) 6 and X-box binding protein-1 (XBP-1). The ERO1α expressions in HHcy mice and Hcy-treated hepatocytes were decreased compared with those in ApoE-/- group and control hepacytes (P < 0.05), respectively. Knocking-down the expression of EROla with small-interfering RNA significantly augmented Hcy-induced ER stress. Meanwhile, the expressions of ER stress-related factor including GRP78, PERK, ATF6 and XBP-1, were significantly decreased when the ERO1α gene was over-expressed in hepacytes. Our results suggested that ERO1α may be involved in Hcy-induced hepar ER stress, and the inhibition of ERO1α expression can accelerate this process.