mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
石河子地区老年人骨质疏松性骨折患者风险评估及相关性

目的评估并分析石河子地区老年人骨质疏松性骨折的风险概率值。方法选择60岁及以上骨质疏松性骨折患者264例,使用世界卫生组织推荐的骨折风险评估工具(FRAX)计算出该患者未来10年主要部位(脊柱、前臂和肱骨近端)发生骨质疏松骨折的概率和髋部骨折(股骨颈和股骨粗隆间)的概率。结果石河子地区老年人主要部位骨折概率值和髋部骨折概率值分别为:5.8±2.7和2.7±1.8;其中,不同年龄组老年人主要部位骨折概率值和髋部骨折概率值整体比较,6个年龄组均存在显著差异(P<0.01),同一年龄组不同性别主要部位骨折概率值比较,女性均大于男性(P<0.05);同一年龄组不同性别髋部骨折概率值比较,70~74岁和80~84岁的女性大于男性(P<0.05);60~64岁年龄组平均风险因子个数与主要部位骨折概率值和髋部骨折概率值的相关系数r分别是0.558和0.645,P<0.01,两者存在着正相关,70~74岁年龄组体质指数与主要部位骨折概率值和髋部骨折概率值的相关系数r分别是-0.385和-0.597,P<0.01,两者存在负相关。结论骨折风险评估工具能够有效地预测本地区老年人未来10年骨折发生的概率,石河子地区60岁以上老年人骨质疏松性骨折病人风险概率值与国外老年人群相比,主要部位骨折的概率值和髋部骨折的概率值都偏低。风险因子个数与体质指数和骨折概率值存在一定的相关性。
早期康复对脊髓损伤患者功能恢复及并发症的影响

目的探讨早期康复对脊髓损伤患者肢体功能及各种并发症发生率的影响。方法入选脊髓损伤患者176例,根据康复治疗开始的时间分为早期治疗组(发病1个月内,90例)和对照组(发病3个月以上,86例)。根据两组患者的不同病程、不同损伤阶段及程度,采用相应的综合康复训练及护理措施。于治疗前及康复治疗3个月后进行ASIA运动评分、日常生活活动能力评定、功能独立性(FIM)评定;并统计两组肺部感染、泌尿系感染、泌尿系结石、肾积水、痉挛、踝关节跟腱挛缩、压力性溃疡、体位性低血压、脊髓损伤后疼痛、下肢深静脉血栓、异位骨化的发生率。比较分析其差异。结果康复治疗后,两组ASIA运动评分、改良Barthel指数评分、FIM评分较治疗前均明显提高(P<0.01),早期治疗组三项评分均明显高于对照组(P<0.05);两组患者并发症发生率比较:早期治疗组肺部感染、泌尿系感染、泌尿系结石、肾积水、痉挛、踝关节跟腱挛缩、压力性溃疡、体位性低血压、中重度以上脊髓损伤后疼痛、下肢深静脉血栓的发生率均明显低于对照组(P<0.05);早期治疗组异位骨化发生率与对照组差异无统计学意义(P>0.05)。结论早期康复治疗可以更好地促进脊髓损伤患者的运动功能恢复;明显减少脊髓损伤后肺部感染、泌尿系统并发症、痉挛、踝关节跟腱挛缩、压力性溃疡、体位性低血压、下肢深静脉血栓及疼痛这些并发症的发生率;尚不能认为早期康复治疗可以预防异位骨化的发生。
发动机制造业作业人员健康促进的干预效果

了解某发动机制造作业人员对职业卫生知识的认知情况以及健康需求。采用整群抽样法,对某企业员工干预前后职业卫生知识认知情况、作业岗位职业病危害因素知晓情况、职业病危害信息获取方式改变、健康行为方式等进行调查。结果显示,干预后员工对职业卫生知识的认知率有了明显提高,员工的行为得到改善,吸烟率降低,吃早餐率升高,多数员工认识到低盐饮食的重要性。提示,健康促进是预防作业人员发生职业病危害的一种简便、可行、有效的方法。
Variations in Toxic Metal Levels of Two Fish Species, Pomatomus saltatrix and Dicentrarchus labrax, and Risk Estimation for Children

The concentrations of five toxic metals were monthly determined in two fish species,obtained from fish markets in Turkey during 2010-2011. For the determinations,AAS and ICP-AES were used. The obtained lead concentrations for all studied Pomatomus saltatrix (mean 635 μg·kg~(-1)) and Dicentrarchus labrax (mean 463 μg·kg~(-1)) samples were found to be significantly higher than the maximum allowances concentration (MAC) of 300 μg·kg~(-1). Mean chromium (324 μg·kg~(-1)) and Cu (940 μg·kg~(-1)) concentrations in Pomatomus saltatrix were higher than in Dicentrarchus labrax (268 μg Cr·kg~(-1) and 600 μg Cu·kg~(-1)) while Ni in Pomatomus saltatrix (216 μg·kg~(-1)) was lower in Dicentrarchus labrax (291 μg·kg~(-1)). The estimated non-carcinogenic and carcinogenic health risks by the Target Hazard Quotient and target carcinogenic risk indicate that there are no sytemic effects,andthe risk of developing cancer over a human lifetime is between 2~9 in 1 000 000.
Development of a superconducting solenoid for CADS

A superconducting focusing solenoid has been designed and developed for the China Accelerator Driven System (CADS). In order to meet the requirement of focusing strength and fringe field while minimizing the physical size of the solenoid, the novel optimizing design method based on a linear programming method was employed. In this report, the design of the solenoid including magnetic field optimization, mechanical design and quench protection will be introduced. The solenoid has been fabricated and tested. The testing results show that the central field reached 8.4 T and the stray field was lower than 50 Gauss in the cavity zone.
Meson decays in an extended Nambu-Jona-Lasinio model with heavy quark flavors

In a previous work, we proposed an extended Nambu-Jona-Lasinio (NJL) model including heavy quark flavors. In this work, we will calculate strong and radiative decays of vector mesons in this extended NJL model, including light ρ, ω, K*; Φ and heavy D*, D_s*, B*, B_s*.
MiR-181c modulates the proliferation, migration, and invasion of neuroblastoma cells by targeting Smad7

MicroRNAs (miRNAs) function as key regulators of gene expression in various cancers. In this study, the aim is to explore the roles and regulation mechanism of miR-181c in neuroblastoma (NB) cells. We found that miR-181c was downregulated in metastatic NB tissues,compared with primary NB tissues. Then functional studies indicated that miR-181c overexpression inhibited NB cell proliferation, migration, and invasion, while miR-181c inhibition increased cell proliferation, migration,and invasion. EGFP reporter assay, real-time polymerase chain reaction and western blot analysis validated that Smad7 was a direct target of miR-181c. MiR-181c reduced Smad7 expression at both mRNA and protein levels. Finally, functional assays showed that the effect of Smad7 knockdown on cells was similar to that of miR-181c overexpression. Importantly, Smad7 overexpression could restore the antitumor effects that were induced by miR-181c. In conclusion, our results demonstrated that miR-181c inhibits NB cell growth and metastasis-related traits through the suppression of Smad7,functioning as a tumor suppressor. Moreover, our results suggested that miR-181c may serve as an important therapeutic target for NB patients.
听力学实践标准

美国听力学学会(the American Academy of Audiology,AAA)的使命是“通过领导、宣传、教育、公众关注和支持科研来推动听力学专业的发展,倡导高质量的听力及平衡服务”。为此,本文成为听力学专业人士及其服务对象的《听力学实践标准》。本文列出的标准集中反映了听力学家应有的职业操守和临床实践。建议读者参照美国听力学学会颁布的《执业许可范围》、《伦理行为准则》、学会立场报告、实践指南以及具有特殊指导意义的核心价值的表述。
Properties of Plasma Enhanced Chemical Vapor Deposition Barrier Coatings and Encapsulated Polymer Solar Cells

In this paper, we report silicon oxide coatings deposited by plasma enhanced chemical vapor deposition technology (PECVD) on 125 μm polyethyleneterephthalate (PET) surfaces for the purpose of the shelf lifetime extension of sealed polymer solar cells. After optimization of the processing parameters, we achieved a water vapor transmission rate (WVTR) of ca. 10~(-3) g/m~2/day with the oxygen transmission rate (OTR) less than 0.05 cc/m~2/day,and succeeded in extending the shelf lifetime to about 400 h in encapsulated solar cells. And then the chemical structure of coatings related to the properties of encapsulated cell was investigated in detail.
红斑肢痛症伴隐-股静脉瓣膜功能不全1例

本例患者为老年性,突然起病,双下肢胫前对称性剧烈疼痛,呈灼热及针刺感,阵发性加重,遇冷减轻,遇热加重,皮肤潮红充血,皮温增高伴出汗,足背动脉及胫前动脉搏动较好。血常规中红细胞数及血小板正常,血沉未见异常,抗核抗体系列检查正常,可排除真性红细胞增多症、血细胞增多症及系统性红斑狼疮引起的继发性红斑肢痛症。另外,患者亦无用药史,因药物继发而出现该症的可能性排除。血糖正常,排除糖尿病引起的周围神经病。询问患者无家族遗传病史。因此根据患者特征性的临床表现及鉴别诊断,本例红斑肢痛症的临床诊断成立。本例患者曾长期站立工作,血管内张力增加,导致下肢隐-股静脉瓣膜功能不全,血液从股总静脉反流至大隐静脉,增加了对邻近神经末梢的压迫和刺激,推测这可能是其老年发病的原因。本病下肢发病率高于上肢,休息后症状缓解都提示本病可能与血管压力增大有关。隐-股静脉瓣膜比较薄弱,位置较浅,缺乏肌肉保护,逐渐被破坏后形成下肢浅静脉曲张,其与红斑肢痛症之间的关系有待大样本临床病例进一步观察。
Investigation of Uncertainties of Establishment Schemes in Dynamic Global Vegetation Models

In Dynamic Global Vegetation Models (DGVMs), the establishment of woody vegetation refers to flowering, fertilization, seed production, germination, and the growth of tree seedlings. It determines not only the population densities but also other important ecosystem structural variables. In current DGVMs, establishments of woody plant functional types (PFTs) are assumed to be either the same in the same grid cell, or largely stochastic. We investigated the uncertainties in the competition of establishment among coexisting woody PFTs from three aspects: the dependence of PFT establishments on vegetation states; background establishment; and relative establishment potentials of different PFTs. Sensitivity experiments showed that the dependence of establishment rate on the fractional coverage of a PFT favored the dominant PFT by. increasing its share in establishment. While a small background establishment rate had little impact on equilibrium states of the ecosystem, it did change the timescale required for the establishment of alien species in pre-existing forest due to their disadvantage in seed competition daring the early stage of invasion. Meanwhile, establishment purely from background (the scheme commonly used in current DGVMs) led to inconsistent behavior in response to the change in PFT specification (e.g., number of PFTs and their specification). Furthermore, the results also indicated that trade-off between individual growth and reproduction/colonization has significant influences on the competition of establishment. Hence, further development of establishment parameterization in DGVMs is essential in reducing the uncertainties in simulations of both ecosystem structures and successions.
The Impact of Global Warming on the Pacific Decadal Oscillation and the Possible Mechanism

The response of the Pacific Decadal Oscillation (PDO) to global warming according to the Fast Ocean Atmosphere Model (FOAM) and global warming comparison experiments of 11IPCC AR4 models is investigated. The results show that North Pacific ocean decadal variability, its dominant mode (i.e., PDO), and atmospheric decadal variability, have become weaker under global warming, but with PDO shifting to a higher frequency. The SST decadal variability reduction maximum is shown to be in the subpolar North Pacific Ocean and western North Pacific (PDO center). The atmospheric decadal variability reduction maximum is over the PDO center. It was also found that oceanic baroclinic Rossby waves play a key role in PDO dynamics, especially those in the subpolar ocean. As the frequency of ocean buoyancy increases under a warmer climate, oceanic baroclinic Rossby waves become faster, and the increase in their speed ratio in the high latitudes is much larger than in the low latitudes. The faster baroclinic Rossby waves can cause the PDO to shift to a higher frequency, and North Pacific decadal variability and PDO to become weaker.
A Velocity Dealiasing Scheme for C-band Weather Radar Systems

A dealiasing algorithm for radar radial velocity observed by C-band Doppler radars is presented as an extension of an existing S-band dealiasing algorithm. This has operational significance in that many portable and many commercial broadcast radars, as well as approximately one half of the Chinese weather radar network (CINRAD), are C-band radars. With a wavelength of about 5 cm, the Nyquist interval of C-band radars is just about one half that of S-band radars (wavelength of about 10 cm) and thus has more velocity folding. The proposed algorithm includes seven modules to remove noisy data, find the starting radiais, dealias velocities, and apply least squares error checking in both the radial and azimuth directions. The proposed velocity dealiasing method was applied to one widespread rain case and three strong convective cases from radars operating in China. It was found that, on average, 92.95% of the aliased radial velocity data could be correctly de-aliased by the algorithm, resulting in 96.65% of the data being valid.
Dynamic and Numerical Study of Waves in the Tibetan Plateau Vortex

In terms of its dynamics, The Tibetan Plateau Vortex (TPV) is assumed to be a vortex in the boundary layer forced by diabatic heating and friction. In order to analyze the basic characteristics of waves in the vortex, the governing equations for the vortex were established in column coordinates with the balance of gradient wind. Based on this, the type of mixed waves and their dispersion characteristics were deduced by solving the linear model. Two numerical simulations with triple-nested domains—one idealized large-eddy simulation and one of a TPV that took place on 14 August 2006—were also carried out. The aim of the simulations was to validate the mixed wave deduced from the governing equations. The high-resolution model output data were analyzed and the results showed that the tangential flow field of the TPV in the form of center heating was cyclonic and convergent in the lower levels and anticyclonic and divergent in the upper levels. The simulations also showed that the vorticity of the vortex is uneven and might have shear flow along the radial direction. The changing vorticity causes the formation and spreading of vortex Rossby (VR) waves, and divergence will cause changes to the motion of the excitation and evolution of inertial gravity (IG) waves. Therefore, the vortex may contain what we call mixed inertial gravity-vortex Rossby (IG-VR) waves. It is suggested that some strongly developed TPVs should be studied in the future, because of their effects on weather in downstream areas.
Greenland Ice Sheet Contribution to Future Global Sea Level Rise based on CMIP5 Models

Sea level rise (SLR) is one of the major socioeconomic risks associated with global warming. Mass losses from the Greenland ice sheet (GrIS) will be partially responsible for future SLR, although there are large uncertainties in modeled climate and ice sheet behavior. We used the ice sheet model SICOPOLIS (Simulation COde for POLythermal Ice Sheets) driven by climate projections from 20 models in the fifth phase of the Coupled Model Intercomparison Project (CMIP5) to estimate the GrIS contribution to global SLR. Based on the outputs of the 20 models, it is estimated that the GrIS will contribute 0-16 (0-27) cm to global SLR by 2100 under the Representative Concentration Pathways (RCP) 4.5 (RCP 8.5) scenarios. The projected SLR increases further to 7-22 (7-33) cm with 2 x basal sliding included. In response to the results of the multimodel ensemble mean, the ice sheet model projects a global SLR of 3 cm and 7 cm (10 cm and 13 cm with 2xbasal sliding) under the RCP 4.5 and RCP 8.5 scenarios, respectively. In addition, our results suggest that the uncertainty in future sea level projection caused by the large spread in climate projections could be reduced with model-evaluation and the selective use of model outputs.
Poly(4-vinylpyridinium)hydrogen sulfate: A novel and efficient catalyst for the synthesis of 13-aryl-indeno[1,2-b]naphtha[1,2-e]pyran-12(13H)-ones under solvent-free conditions

An facile and efficient protocol for the synthesis of 13-aryl-indeno[1,2-b]naphtha[1,2-e]pyran-12(13H)-ones has been developed that proceeds via the one-pot three-component sequential reaction of an aromatic aldehyde with β-naphthol and 2H-indene-1,3-dione under solvent-free conditions in the presence of a poly(4-vinylpyridinium)hydrogen sulfate (P(4-VPH)HSO_4) catalyst. The catalyst can be reused several times, making this procedure facile, practical, and sustainable. The simple experimental procedure, solvent-free reaction conditions, use of an inexpensive catalyst, short react time, and excellent yields are some of the major advantages of this methodology.
H_3PW_(12)O_(40) catalyzed synthesis of benzoxazine and quinazoline in aqueous media

A heteropolyacid efficiently catalyzed the cyclocondensation reaction of 2-aminobenzamide and salicylamide with aldehydes and ketones to afford good yields of benzoxazine and quinazoline ring systems in an aqueous medium. The method gives clean reactions, has simple workup procedure, and uses environment friendly conditions.
Wet air oxidation for the decolorization of dye wastewater: An overview of the last two decades

Wet air oxidation (WAO), a liquid phase reaction between organic materials in water and oxygen, is one of the most economical and technologically viable advanced oxidation processes for wastewater treatment, particularly toxic and high organic content wastewater. WAO is the liquid phase oxidation of organics or oxidizable inorganic components at elevated temperatures (125-320 °C) and pressures(0.5-20 MPa) using gaseous oxygen(or air) as oxidant. In the past two decades, the WAO process was widely studied and applied in the treatment of dye wastewater. Compared to conventional WAO, catalytic WAO processes have higher efficiency and use moderate reaction conditions. The catalysts included homogenous and heterogeneous types. The key points that need to be solved are recycling of homogenous catalysts and better stability of heterogeneous catalysts. In the present review, the technological processes are first introduced, then some research history and hotspots of WAO research are presented, and finally, its application in the treatment of dye wastewater in the past two decades is summarized to reveal the impressive changes in modes, trends, and conditions used. The application includes model pollutant studies and wastewater tests.
Intercomparison of GPS radiosonde soundings during the eastern tropical Indian Ocean experiment

Temperature and relative humidity profiles derived from two China-made global positioning system (G-PS) radiosondes (GPS-TK and CF-06-A) during the east tropical Indian Ocean (ETIO) experiment were compared with Vaisala RS92-SGP to assess the performances of China-made radiosondes over the tropical ocean. The results show that there have relative large biases in temperature observations between the GPS-TK and the RS92-SGP in the low troposphere, with a warm bias of greater than 2 K in the day and a cooling bias of 0.6 K at night. The temperature differences of the CF-06-A were small in the troposphere both in daytime and nighttime, and became large peak-to-peak fluctuations in the stratosphere. The intercom-parison of the relative humidity showed that the CF-06-A had large random errors due to the limitation of sensors and the lack of correction scheme, and the GPS-TK had large systematic biases in the low tropo-sphere which might be related to the temperature impact. GPS height measurements are clearly suitable for China-made radiosonde systems operation. At night, the CF-06-A and the GPS-TK could provide virtual potential temperature and atmospheric boundary layer height measurements of suitable quality for both weather and climate research. As a result of the intercomparison experiment, major errors in the China-made radiosonde systems were well indentified and subsequently rectified to ensure improving accuracy for historical and future radiosondes.
Estimation of eddy heat transport in the global ocean from Argo data

The Argo data are used to calculate eddy (turbulence) heat transport (EHT) in the global ocean and analyze its horizontal distribution and vertical structure. We calculate the EHT by averaging all the v′, T′ profiles within each 2o × 2o bin. The velocity and temperature anomalies are obtained by removing their clima-tological values from the Argo“instantaneous”values respectively. Through the Student’s t-test and an error evaluation, we obtained a total of 87% Argo bins with significant depth-integrated EHTs (D-EHTs). The results reveal a positive-and-negative alternating D-EHT pattern along the western boundary currents (WBC) and Antarctic Circumpolar Current (ACC). The zonally-integrated D-EHT (ZI-EHT) of the global o-cean reaches 0.12 PW in the northern WBC band and-0.38 PW in the ACC band respectively. The strong ZI-EHT across the ACC in the global ocean is mainly caused by the southern Indian Ocean. The ZI-EHT in the above two bands accounts for a large portion of the total oceanic heat transport, which may play an important role in regulating the climate. The analysis of vertical structures of the EHT along the 35oN and 45oS section reveals that the oscillating EHT pattern can reach deep in the northern WBC regions and the Agulhas Return Current (ARC) region. It also shows that the strong EHT could reach 600 m in the WBC re-gions and 1 000 m in the ARC region, with the maximum mainly located between 100 and 400 m depth. The results would provide useful information for improving the parameterization scheme in models.
不同麻醉方式在老年支气管镜检查中的效果比较

随着内镜技术的发展,支气管镜逐渐成为呼吸科医师诊断和治疗肺、支气管疾病的重要手段;随着无痛技术在胃、肠镜检查中的广泛应用,无痛支气管镜检查术也逐步走向成熟。支气管镜检查术的操作对咽喉部的刺激强度大,易出现呼吸抑制和气道梗阻,对麻醉要求较高。尤其是老年患者常存在一定程度的通气、换气功能障碍,高强度的刺激后易出现血流动力学变化,甚至会导致心血管不良事件的发生。因此,临床医师对老年患者行支气管镜检查时麻醉方式的选择更加关注。目前临床常用的3种麻醉方式为表面麻醉、表面麻醉+清醒镇静和喉罩置管全身麻醉。本研究旨在观察并比较以上麻醉方式在70岁以上行支气管镜检查的老年患者中的效果。
上海市心脏手术麻醉的变迁

以人为鉴,可以明得失;以史为鉴,可以知兴替。人生如白驹过隙,若你行色匆匆便会错过沿途美丽的风景。本文通过回顾上海市心脏麻醉的变迁过程,总结近年来上海市麻醉科医师在心血管麻醉领域的成绩与不足,以更好地把握心脏麻醉的发展脉动,服务于患者。
贮存式自体输血采血策略与免疫调节研究进展

贮存式自体输血(preoperative autologous blood donation,PABD)是指在手术数周乃至数月前预先采集患者自身血液(全血或分离成分)保存,在其需要输血治疗时进行回输保存的血液。PABD包括全血PABD和血液成分PABD,血液成分PABD又包括红细胞PABD、血浆PABD、血小板PABD和外周血造血干细胞PABD。在欧美等一些发达国家,随着人口逐渐进入老龄化,志愿献血者数量不断下降,血液来源也逐渐,减少,同时伴随着手术和非手术患者的数量增多和用血量的上升,尤其是整形、心血管和肿瘤等手术输血需求的惊人增加,血源紧缺已经越来越成为一个急需解决的问题。这也促使医务工作者考虑采用其它方式来满足临床用血,比如发展自体输血技术,尤其是PABD,是一种较好的替代途径。在一些国家,政府制定一些法律来要求临床医生对可能需要输血的择期手术患者进行PABD或其它医疗措施来降低异体用血的需求。PABD已经成为一种术前备血标准操作程序来应用于择期手术,本文对PABD临床应用进展进行综述。
抗风疹病毒IgM类抗体生物素- 亲合素时间分辨荧光免疫分析捕获法的建立与性能评价

目的建立抗风疹病毒IgM类抗体(RV IgM)生物素-亲合素时间分辨荧光免疫分析捕获法(BA Mac TrFIA)并评价其分析性能。方法用鼠抗人μ链单克隆抗体(抗-μ McAb)作为包被抗体,生物素化RV重组抗原为桥接抗原,链霉亲合素标记铕作为示踪物,配制以β-萘甲酰三氟丙酮为主要成分的增强液,测定抗RV IgM抗体,并对其检测限、重复性、阴性参考品符合率、阳性参考品符合率、试剂热稳定性进行评价,与同类方法学比对检测1 020例样本,比对实验的一致性分析采用Kappa 检验。结果本方法检测国家检测限参考品L1、L2和L3的结果均为阳性反应(S/CO≥1.00),批内变异系数(CV)<15.00%,国家阴性参考品符合率为10/10,国家阳性参考品符合率为5/5;本方法的试剂盒于37 ℃恒温放置6 d后,检测性能无明显改变;与珠海海泰公司试剂结果符合率为98.82%,Kappa =0.96。结论本方法灵敏度高,特异性强,精密度好;与同类方法学检测结果相关性好,能满足临床应用需要。
~(137)Cs γ-射线诱导小鼠胚胎成纤维细胞衰老模型的建立

随着老龄人口的增加,各种老年疾病随之而来,如何延缓衰老已经成为世界各国学者研究的热点。研究衰老机制,建立衰老模型尤为必要。有学者根据衰老的自由基理论,利用一定剂量的γ 射线照射建立衰老模型,但检测的衰老相关指标较少。为此采用~(137)Cs γ 射线照射小鼠胚胎成纤维细胞(mouseembryo fibroblast,MEF),探讨衰老模型的建立。
慢性阻塞性肺疾病患者血清脂联素检测及其临床意义

慢性阻塞性肺疾病(COPD)是一种气道慢性非特异性炎症性疾病，主要由呼吸道的多种炎症细胞激活浸润并释放多种炎症因子导致。脂联素(APN)是一种脂肪组织细胞分泌的细胞因子，研究表明气道上皮细胞也能分泌APN，通过自分泌或旁分泌途径对COPD炎症过程具有调节作用，但目前对APN在COPD中与炎症因子作用机制尚未清楚，对COPD不同时期APN水平增加或降低的研究结果尚未达到一致。本研究探讨APN检测在COPD患者中的临床意义。
西格列汀对糖尿病前期人群的干预效果

目的探讨西格列汀对糖尿病前期(IGR)人群的治疗效果。方法将徐州地区流行病学调查筛出的连续1年均为糖尿病前期的患者及糖尿病前期人群197例。分为三个组：空腹血糖受损(IFG)组、糖耐量异常组（IGT）和混合型糖调节异常（IFG/ IGT）组，并将各组分为常规治疗组（对照组）和西格列汀强化治疗组（西格列汀组）两个亚组，对照组仅予以生活方式指导，西格列汀组在生活方式干预的同时予以西格列汀。随访1年，分析转归及影响因素，并比较西格列汀对糖尿病前期人群的治疗效果。结果1年后西格列汀组血糖、体重指数达标率显著高于对照组(P<0.05)。西格列汀组的胰岛功能改善明显优于对照组(P<0.05)。西格列汀组有2例进展为糖尿病，而对照组共14例进展为糖尿病。IFG/IGT干预组的糖化血红蛋白水平优于IFG和IGT组，IGT组的餐后2 h胰岛素水平及胰岛素抵抗水平改善优于IFG和IFG/IGT组。结论西格列汀可以改善糖尿病前期人群的餐后2 h胰岛素分泌水平和胰岛素抵抗，在IGT人群尤为明显。西格列汀能够降低糖尿病前期人群糖尿病的发病率。
超级电容器在电梯节能中的应用

对电梯能耗进行了分析,提出了以超级电容器为储能器件的电梯节能方案,并介绍了一些应用实例。基于超级电容器的技术优势,估算了该技术的节能效果,展望了在电梯节能领域的广阔应用前景。
Influence of Blade Wrap Angle on Centrifugal Pump Performance by Numerical and Experimental Study

The existing research on improving the hydraulic performance of centrifugal pumps mainly focuses on the design method and the parameter optimization. The traditional design method for centrifugal impellers relies more on experience of engineers that typically only satisfies the continuity equation of the fluid. In this study, on the basis of the direct and inverse iteration design method which simultaneously solves the continuity and motion equations of the fluid and shapes the blade geometry by controlling the wrap angle, three centrifugal pump impellers are designed by altering blade wrap angles while keeping other parameters constant. The three-dimensional flow fields in three centrifugal pumps are numerically simulated, and the simulation results illustrate that the blade with larger wrap angle has more powerful control ability on the flow pattern in impeller. The three pumps have nearly the same pressure distributions at the small flow rate, but the pressure gradient increase in the pump with the largest wrap angle is smoother than the other two pumps at the design and large flow rates. The pump head and efficiency are also influenced by the blade wrap angle. The highest head and efficiency are also observed for the largest angle. An experiment rig is designed and built to test the performance of the pump with the largest wrap angle. The test results show that the wide space of its efficiency area and the stability of its operation ensure the excellent performance of the design method and verify the numerical analysis. The analysis on influence of the blade wrap angle for centrifugal pump performance in this paper can be beneficial to the optimization design of the centrifugal pump.
本期部分亮点

《化工学报》2014年第1期为化学工程联合国家重点实验室专刊,发表了该重点实验室近期取得的一些研究成果,涉及反应工程、分离工程、系统工程、产品工程以及材料化工等内容,总体反映了化学工程联合国家重点实验室的研究特色和研究方向,一些研究工作既为学术前沿问题,又是面向国家重大需求。 因为篇幅有限,在此仅列举其中部分亮点供读者参考。
急性心肌梗死并发心源性休克患者不同治疗方案中应用主动脉内球囊反搏术对预后的影响

与随机对照试验对比， 观察性研究容易出现偏差。理论上说，纳入荟萃分析的研究应严格控制为随机对照研究，但本研究纳入了13个观察性研究，作者认为，可以结合随机效应模型的概率敏感性分析技术来调整混杂因素， 但精心设计的观察性研究的结果与随机对照试验相比仍不能系统地评估治疗效果。本分析的另一个潜在的局限性因素是在无灌注药物治疗亚组中应用IABP无显著效果可能是因为研究规模小的缘故。