mlsa-iai-msu-lab/ru_sci_bench_zho_cite_reranking huggingface dataset:
Mechanical properties of irradiated multi-phase polycrystalline BCC materials

Structure materials under severe irradiations in nuclear environments are known to degrade because of irradiation hardening and loss of ductility, resulting from irradiation-induced defects such as vacancies, interstitials and dislocation loops, etc. In this paper, we develop an elastic–viscoplastic model for irradiated multi-phase polycrystalline BCC materials in which the mechanical behaviors of individual grains and polycrystalline aggregates are both explored. At the microscopic grain scale, we use the internal variable model and propose a new tensorial damage descriptor to represent the geometry character of the defect loop, which facilitates the analysis of the defect loop evolutions and dislocation-defect interactions.At the macroscopic polycrystal scale, the self-consistent scheme is extended to consider the multiphase problem and used to bridge the individual grain behavior to polycrystal properties. Based on the proposed model, we found that the work-hardening coefficient decreases with the increase of irradiation-induced defect loops, and the orientation/loading dependence of mechanical properties ismainly attributed to the different Schmid factors. At the polycrystalline scale, numerical results for pure Fe match well with the irradiation experiment data. The model is further extended to predict the hardening effect of dispersoids in oxide-dispersed strengthened steels by the considering the Orowan bowing. The influences of grain size and irradiation are found to compete to dominate the strengthening behaviors of materials.
Analysis of the Structure and Propagation of a Simulated Squall Line on 14 June 2009

A squall line on 14 June 2009 in the provinces of Jiangsu and Anhui was well simulated using the Advanced Regional Prediction System (ARPS) model. Based on high resolution spatial and temporal data, a detailed analysis of the structural features and propagation mechanisms of the squall line was conducted. The dynamic and thermodynamic structural characteristics and their causes were analyzed in detail. Unbalanced flows were found to play a key role in initiating gravity waves during the squall line’s development. The spread and development of the gravity waves were sustained by convection in the wave-CISK process. The squall line’s propagation and development mainly relied on the combined effect of gravity waves at the midlevel and cold outflow along the gust front. New cells were continuously forced by the cold pool outflow and were enhanced and lifted by the intense upward motion. At a particular phase, the new cells merged with the updraft of the gravity waves, leading to an intense updraft that strengthened the squall line.
Activation of Mo/HZSM-5 for methane aromatization

The effect of Mo/HZSM-5 pretreatment at 973 K in inert (He), oxidizing (artificial air), and carburizing(CH4/He mixture) atmospheres on its performance in non-oxidative methane dehydroaromatization(MDA) was investigated. The effect of post-synthesis silylation on deactivation of external acid sites was also studied. Precarburization resulted in increased aromatic selectivity and improved catalyst stability. The benzene selectivity was the highest for the silylated Mo/HZSM-5 catalyst(benzene + naphthalene selectivity after 1 h on stream was close to 100%). The deactivation of precarburized zeolites was less pronounced than that of zeolites heated in air or He. During heating in air or He, larger fractions of the molybdenum oxide species diffused into the micropores than during heating in methane. Carburization of the molybdenum oxide species in the micropores during MDA resulted in the formation of molybdenum carbide particles, and these contributed to pore blocking, making the Bronsted acid sites inaccessible. The formation of molybdenum carbides during heating in methane resulted in a less mobile Mo phase. It is argued that the presence of molybdenum carbide particles in the micropores contributes to rapid catalyst deactivation, in addition to the formation of hard coke on the external surface.
抗苗勒管激素的相关影响因素研究进展

抗苗勒管激素(anti-Mullerian hormone, AMH),也被称为苗勒管抑制物质(Mullerian inhibition substance, MIS),是1种肽类生长因子,属于组织生长因子β超家族。在女性,AMH特异性地由始基卵泡池内启动生长后的卵泡中的颗粒细胞产生,主要由窦前卵泡和小窦状卵泡分泌,从原始卵泡起持续到卵泡直径约8 mm时停止,其在较大的窦状卵泡中的水平非常低,在FSH依赖的优势卵泡中和闭锁卵泡中均无AMH形成;其主要的生理作用是在卵泡募集早期起调控作用,抑制卵泡从始基卵泡到窦状卵泡的初级募集。颗粒细胞分泌到卵泡液中的AMH可进入血液循环,故取血清标本可检测AMH。女婴刚出生时血清中几乎检测不到AMH,青春期前AMH水平递增,于25 ~30岁基本恒定于峰值,而后随年龄逐渐下降,直至自发绝经后降至检测范围以下。
连续性血液净化治疗脓毒症合并腹腔高压的疗效观察

重症加强治疗病房(ICU)的危重患者通常由于多种原因可引起腹壁顺应性降低、腹腔内容物增加或间质性水肿、第三间隙液体集聚,因而导致腹腔内高压/腹腔间室综合征(IAH/ACS)。IAH/ACS的发生发展与器官衰竭、病死率的增加密切相关,并且被认为是ICU患者预后的独立预测因素。对于危重患者需尽早监测腹腔内压(IAP),警惕IAH的发生;一旦IAH进展至ACS,病死率将明显增加,内科治疗难度明显增加,严重情况下需要行开腹减压术。所以早期监测危重患者IAP,早期发现、早期治疗IAH具有重要的临床意义。
Stepping Control Method of Linear Displacement Mechanism Driven by TRUM Based on PSoC

A method based on programmable system-on-chip(PSoC)is proposed to realize high resolution stepping motion control of liner displacement mechanism driven by traveling wave rotary ultrasonic motors(TRUM).Intelligent controller of stepping ultrasonic motor consists of PSoC microprocessor.Continuous square wave signal is sent out by the pulse width modulator(PWM)module inside PSoC,and converted into sinusoidal signal which is essential to the motor′s normal working by power amplifier circuit.Subsequently,signal impulse transmission is realized by the counter control break,and the stepping motion of linear displacement mechanism based on TRUM is achieved.Running status of the ultrasonic motor is controlled by an upper computer.Control command is sent to PSoC through serial communication circuit of RS-232.Relative program and control interface are written in Lab- View.Finally the mechanism is tested by XL-80 laser interferometer.Test results show that the mechanism can provide a stable motion and a fixed step pitch with the displacement resolution of 6 nm.
Frequency-Speed Control Model Identification of Ultrasonic Motor Using Step Response

Control model of ultrasonic motor is the foundation for high control performance.The frequency of driving voltage is commonly used as control variable in the speed control system of ultrasonic motor.Speed control model with the input frequency can significantly improve speed control performance.Step response of rotating speed is tested.Then,the transfer function model is identified through characteristic point method.Considering time-varying characteristics of the model parameters,the variables are fitted with frequency and speed as the independent variables,and the variable model of ultrasonic motor system is obtained,with consideration of the nonlinearity of ultrasonic motor system.The proposed model can be used in the design and analysis of the speed control system in ultrasonic motor.
Influence of Friction Interface Contact on Ultrasonic Motor Efficiency Under Static Conditions

The friction interface matching plays a deterministic role in the motor efficiency,and the microcosmic contact status of friction interface should be investigated to improve the ultrasonic motor performance.The main purpose is to improve the effective output power of ultrasonic motor.Hence,one studies the contact condition of the friction interface of the ultrasonic motor,analyzes the micro condition of contact interface through finite element analysis,optimizes unreasonable structures,and compares the two different-structure ultrasonic motors through experiments.The results reflect the necessity of optimization.After optimization,the stator and rotor deform after pre-pressure and the contact interface of them full contact theoretically.When reaching heat balance the effective output of the motor is 37%,and the average effective output efficiency is 2.384times higher than that of the unoptimized.It can be seen that the total consumption of the ultrasonic motor system decreases significantly. Therefore,when using in certain system the consumption taken from the system will decreases largely,especially in the system with a strict consumption control.
Friction Behavior on Contact Interface of Linear Ultrasonic Motor with Hard Contact Materials

How to improve the efficiency of the linear ultrasonic motor with hard contact materials(HLUSM)or the precision motion stage driven by HLUSM,becomes a hot issue.Analysis and testing of friction behavior on the contact interface of HLUSM is one of the key issues.Under the action of ultrasonic vibration and impact,the friction behavior on contact interface is very complex due to micro-amplitude and high frequency.Moreover,it is difficult to observe and test it.Focusing on the frictional behavior on the interface of HLUSM,a new method,through testing the vibration of the driving tips(scanning vibrometer PSV-400-3 D)and the motion of the slider(displacement sensor LK-G30),respectively,is proposed.Then,take the HLUSM as an example,theoretical analyses and experiments are carried out.Theoretical analysis shows that the average speed of the slider should be 600 mm/s when there is no slippage between the stator and slider during the contact process.Experimental results show that the average speed of the slider is about 390 mm/s.At the same time,the tangential vibration speed of the driving tip of HLUSM is larger than 600 mm/s.Therefore,there must be slippage between the stator and slider of HLUSM.Further experimental results show that the maximum efficiency is less than 10%.The slippage on the contact interface should be the main reason for the low efficiency of HLUSM.
冷蒸汽-原子荧光光谱法测定水样中3种形态的汞

汞在环境中的迁移和毒性,随其形态不同而不同。仅测定其总量的方法已不能适应汞化学的深入研究,对形态汞的测定,难点在测定前的化学处理。本工作在文献的基础上,提出了冷蒸汽发生-原子荧光光谱法测定水样中3种形态汞(无机汞、有机汞和总汞),以应对各种环境影响评价的不同要求。
盐渍化土壤中蓝细菌的生态学研究

蓝细菌是一类进化历史悠久、能光合固碳产氧的原核生物。它们的环境适应能力极强,在海洋、淡水及土壤等自然环境中分布广泛。另外,在地球两极、冰川、沙漠等极端环境中也有发现,并有“先锋生物”之称[1]。蓝细菌是全球海洋初级生产的重要贡献者[2-3],在贫瘠土壤中可改良土壤结构,提高土壤保肥保水能力。因此,蓝细菌多样性及其生态分布的研究对理解它们在生物地球化学循环中的贡献及其适应性具有显著的科学意义。
腰椎终板Modic改变的影响因素及临床治疗进展

椎体软骨终板分为骨性终板和软骨终板, 其作用非常重要,对维持脊柱的整体以及椎间盘的功能有重要的意义,研究表明终板的生物力学和生物化学特性的改变容易引起椎间盘退变相关疾病。腰椎终板及终板下骨质在MRI上的信号改变被称为Modic改变,其发生率正常人群中为6%, 腰背痛人群中为40%,Modic改变在中年会进展,而且具有一定的遗传易感性。伴有Modic改变更容易影响腰痛患者的工作和生活。因此Modic改变自提出以来,激起了众多学者的研究热情,然至今其影响因素及临床治疗仍充满争议。笔者对近几年国内外临床研究最新展综述如下。
A new technique for islanding operation of distribution network connected with mini hydro

An islanding operation of a distribution network is a topic of interest due to the significant penetration of distributed generation (DG) in a power system network. However, controlling the frequency of an islanded distribution system remains an unresolved issue, especially when the load exceeds the generation. This paper presents a new technique for a successful islanding operation of a distribution network connected with multiple mini hydro based DGs. The proposed technique is based on three main parts. The first part uses an islanding detection technique to detect the islanding event correctly. The second part consists of a power imbalance estimation module (PIEM), which determines the power imbalance between the generation and load demand. The third part consists of a load shedding controller, which receives the power imbalance value and performs load shedding according to load priority. The proposed technique is validated on an 11 kV existing Malaysia distribution network. The simulation results show that the proposed technique is effective in performing a successful islanding operation by shedding a significant number of loads.
Molecular characterization of an IL-1β gene from the large yellow croaker (Larimichthys crocea) and its effect on fish defense against Vibrio alginolyticus infection

Interleukin 1β (IL-1β), the first interleukin to be characterized, plays a key role in regulating the immune response. In this study, we determined the cDNA and genomic DNA sequences of the IL-1β gene from the large yellow croaker, Larimichthys crocea. Phylogenetic analysis indicated that the IL- 1β (LcIL-1β) gene was most closely related to that of European seabass (Dicentrarchus labrax), sharing 67.8% amino acid identity. In healthy large yellow croaker, LcIL-1β transcription was detected in all tested tissues, with the highest level found in the head kidney. Upon Vibrio alginolyticus infection, LcIL-1β transcription in all tested tissues was significantly upregulated. Intraperitoneal injection of recombinant LcIL-1β (rLcIL-1β) improved the survival rate and reduced the tissue bacterial load after V. alginolyticus infection. In addition, rLcIL-1β induced monocytes/macrophages (MO/MΦ) chemotaxis and increased phagocytosis and bactericidal activity in vitro. These results suggest that LcIL-1β plays an important role in the large yellow croaker immune response against V. alginolyticus.
1例右后侧臀部压疮伴发左侧肺炎患者的护理体会

患者入院时即有肺炎,意识不清,气管插管辅助通气,痰液黏稠不易咳出,每次变换体位后给予叩背,并给予持续气道内湿化以稀释痰液,使用祛痰清肺仪治疗(1次/d)。入院后因过多的左侧卧位导致3 d后肺炎由右侧扩展为双侧,以左肺为著,感染指标上升,考虑较长时间单侧卧位致单侧痰液引流不畅堵塞支气管导致。给予调整体位、加强吸痰后患者压疮加重,及时与医生沟通,于压疮处加强换药,当肺部感染逐渐吸收后鼓励患者自行活动,变换体位,压疮亦逐渐好转。
CO observations towards a sample of nearby galaxies

We have simultaneously observed ~(12)CO, ~(13)CO and C~(18)O (J = 1 - 0) rotational transitions in the centers of a sample of 58 nearby spiral galaxies using the 13.7-m millimeter-wave telescope administered by Purple Mountain Observatory. Forty-two galaxies were detected in ~(13)CO emission, but there was a null detection for C~(18)O emission with a a upper limit of 2 mK. The central beam ratios, R, of ~(12)CO and ~(13)CO range mostly from 5 to 13, with an average value of 8.1 ±4.2, which is slightly lower than previous estimates for normal galaxies. Clear correlations are found between ~(12)CO and ~(13)CO luminosities. An average X factor of 1.44 ± 0.84 x 10~(20) cm~(-2) (K km s~(-1))~(-1) is slightly lower than that in the Milky Way.
Toward the complete relational graph of fundamental circuit elements

A complete and harmonized fundamental circuit relational graph with four linear and four memory elements is constructed based on some newly defined elements, which provides a guide to developing novel circuit functionalities in the future. In addition to resistors, capacitors, and inductors, which are defined in terms of a linear relationship between charge q, current i, voltage v, and magnetic flux φ, Chua proposed in 1971 a fourth linear circuit element to directly relate φ and q. A nonlinear resistive device defined in memory i–v relation and dubbed memristor, was later attributed to such an element and has been realized in various material structures. Here we clarify that the memristor is not the true fourth fundamental circuit element but the memory extension to the concept of resistor, in analogy to the extension of memcapacitor to capacitor and meminductor to inductor. Instead, a two-terminal device employing the linear ME effects, termed transtor, directly relates φ and q and should be recognized as the fourth linear element. Moreover, its memory extension, termed memtranstor, is proposed and analyzed here.
The influence of phonon bath on the control of single photon

The influence of vacuum fluctuation and phonon bath on the probability of single photon emission are both considered in the two-level system model theoretically; by using the master equations and generating function method we get the analytical expression of the second-order fluorescence correlation function, probability of single photon emission, and Mandel’s Q parameter. The results manifest that the coupling between the phonon bath and single photon source destroys the superposition state induced by the square laser pulse, the Rabi oscillation damped rapidly with the increasing of temperature. Theoretically, when the structure parameter of arsenide quantum dots a scaled to 0.1 times of the sample, the critical coherence-temperature will rise up to hundreds of Kelvin, which means a step forward to the realization of coherent control of single photon source at room temperature.
Compound eyes of insects and crustaceans: Some examples that show there is still a lot of work left to be done

Similarities and differences between the 2 main kinds of compound eye (apposition and superposition) are briefly explained before several promising topics for research on compound eyes are being introduced. Research on the embryology and molecular control of the development of the insect clear-zone eye with superposition optics is one of the suggestions, because almost all of the developmental work on insect eyes in the past has focused on eyes with apposition optics. Age- and habitat-related ultrastructural studies of the retinal organization are another suggestion and the deer cad Lipoptena cervi, which has an aerial phase during which it is winged followed by a several months long parasitic phase during which it is wingless, is mentioned as a candidate species. Sexual dimorphism expressing itself in many species as a difference in eye structure and function provides another promising field for compound eye researchers and so is a focus on compound eye miniaturization in very small insects, especially those that are aquatic and belong to species, in which clear-zone eyes are diagnostic or are tiny insects that are not aquatic, but belong to taxa like the Diptera for instance, in which open rather than closed rhabdoms are the rule. Structures like interommatidial hairs and glands as well as corneal microridges are yet another field that could yield interesting results and in the past has received insufficient consideration. Finally, the dearth of information on distance vision and depth perception is mentioned and a plea is made to examine the photic environment inside the foam shelters of spittle bugs, chrysales of pupae and other structures shielding insects and crustaceans.
Genitalia-associated microbes in insects

In sexual reproduction different types of symbiotic relationships between insects and microbes have become established. For example, some bacteria have evolved almost exclusive vertical transmission and even define the compatibility of insect mating partners. Many strictly sexually transmitted diseases have also been described in insects. Apart from such rather specific relationships the role of opportunistic infections in the reproductive process has been widely neglected. Opportunistic microbes transmitted passively during mating might impose an energetic cost, as the immune system will need to be alert and will use resources to fight potential intruders. Through mating wounds and contaminated reproductive organs opportunistic microbes might be transferred to mating partners and even enter the body cavity. Females as the “receiving” sex are particularly likely to have evolved adaptations to avoid or reduce opportunistic infections. Males of several species show highly complex seminal fluids, which as well as containing components that influence a males’ fertilization success, also possess antimicrobial substances. The role of antimicrobials in the reproductive process is not well understood. Some evidence hints at the protection of sperm against microbes, indicating a role for natural selection in shaping the evolution of reproductive traits. By highlighting the potential importance of microbes in sexual selection and their role in reproduction in general I will make a case for studies in sexual selection, especially the ones investigating postcopulatory processes, that should incorporate environmental, as well as genotypic variation, in reproductive traits.
Genetic variation amongst biotypes of Dactylopius tomentosus

The tomentose cochineal scale insect, Dactylopius tomentosus (Lamarck) (Hemiptera: Dactylopiidae), is an important biological control agent against invasive species of Cylindropuntia (Caryophyllales: Cactaceae). Recent studies have demonstrated that this scale is composed of host-affiliated biotypes with differential host specificity and fitness on particular host species.We investigated genetic variation and phylogenetic relationships among D. tomentosus biotypes and provenances to examine the possibility that genetic diversity may be related to their host-use pattern, and whether their phylogenetic relationships would give insights into taxonomic relatedness of their host plants. Nucleotide sequence comparison was accomplished using sequences of the mitochondrial cytochrome c oxidase I (COI) gene. Sequences of individuals from the same host plant within a region were identical and characterized by a unique haplotype. Individuals belonging to the same biotype but from different regions had similar haplotypes. However, haplotypes were not shared between different biotypes. Phylogenetic analysis grouped the monophyletic D. tomentosus into 3 well-resolved clades of biotypes. The phylogenetic relationships and clustering of biotypes corresponded with known taxonomic relatedness of their hosts. Two biotypes, Fulgida and Mamillata, tested positive forWolbachia (α-Proteobacteria), a common endosymbiont of insects. The Wolbachia sequences were serendipitously detected by using insect-specific COI DNA barcoding primers and are most similar to Wolbachia Supergroup F strains. This study is the first molecular characterization of cochineal biotypes that, together with Wolbachia sequences, contribute to the better identification of the biotypes of cochineal insects and to the biological control of cacti using host-specific biotypes of the scale.
2003 -2012年高压氧医学相关护理文献分析

近年来,高压氧治疗被越来越多的人所认识,治疗的疾病涉及临床各个学科,尤其是在各种危重患者的救治过程中,显示了明显的优势。随着高压氧医学的发展,高压氧治疗的相关护理也日趋专业化与系统化,高压氧相关的护理论文也日渐增多。科技论文是在科学研究和发展进程中形成的产物,是基础研究和应用研究成果的具体体现,是促成科技成果转化为生产力的重要手段。通过科技论文的数量和质量以及消长趋势可以衡量科研人员的科研能力、专长与分布,了解地域科技水平、新兴的前沿科技领域等情况。对科技论文产出情况作定量的描述和分析,是目前重要的科技统计工作之一。为客观反映高压氧护理学科科研产出和学术水平,促进高压氧护理学科的发展和完善,笔者对2003 -2012年9种核心期刊中高压氧相关护理文献进行回顾性分析,以便了解当前高压氧相关护理研究的焦点,发现护理科研中尚存在的问题,为今后更好地进行高压氧护理科研工作提供参考。
“和谐使命-2014”南太平洋四国门巡诊常见皮肤病初步分析

“和谐使命-2014”任务出访国家包括位于南太平洋地区的汤加、斐济、瓦努阿图和巴布亚新几内亚4国。笔者收集了此次任务在医院船就诊的南太平洋4国皮肤病患者的基本资料,并对疾病种类进行了分析,总结各个国家的常见皮肤病患病特点及其规律,为我军未来再次执行类似任务时专科药品准备提供参考,并为南太平洋地区国家执行其他任务时皮肤病的防治提供经验。
高压氧预处理联合术前化疗治疗骨肉瘤18例疗效观察

骨肉瘤(osteosarcoma)是最常见的骨恶性肿瘤,占骨原发恶性肿瘤的20% ,发病年龄在10~30岁,约占75% 。骨肉瘤生物学行为多呈高度恶性,早期即易通过血液发生转移。近年来,随着新辅助化疗方案的出现,以及外科保肢手术的创新,骨肉瘤患者的生存率大大提高,但骨肉瘤仍是致残率、死亡率均较高的肿瘤。手术前的新辅助化疗是目前骨肉瘤治疗的新方法,可有效缩小肿瘤体积,促进肿瘤细胞坏死,提高保肢术的手术成功率及降低术后复发。已有研究证明,高压氧可有效提高某些恶性肿瘤化疗的作用,如恶性淋巴瘤、恶性胶质瘤等。自2000年6月以来,我院对18例骨肉瘤患者术前化疗3个周期,同时采用高压氧进行预处理治疗,现将其对化疗效果的影响报道如下。
经皮内镜下胃/空肠造口管护理会诊的做法与体会

Gauderer等于1980年首次介绍了经皮内镜下胃造口术(percutaneous endoscopic gast rostomy, PEG),1984年,Ponsky等在此基础上又发展了经皮内镜下空肠造口术(percutaneous endoscopic jejunostomy, PEJ)。PEG和PEJ是在内镜引导下,经皮穿刺放置胃和空肠造瘘管,以达到胃肠营养和/或减压的目的,是一种微创技术,用于建立长期肠内营养途径、胃肠减压、胆汁回输和治疗胃扭转等,主要适应于各种原因导致的不能经口进食且需要长期营养支持及留置鼻胃管超过1个月或不耐受鼻胃管者、长期昏迷不能自行进食的患者,尤其适用于多种常见的神经系统疾病患者,特别是脑血管病所致的吞咽功能丧失需行胃肠内营养支持的患者。尽管PEG/PEJ具有操作简便、安全、创伤小等优点,但如果应用或护理不当,将引起严重的并发症,增加患者的痛苦。江志伟等于2004年报道的120例PEG/PEJ患者中,严重并发症发生率为0.8%(1/120),其他并发症发生率为7.5% (9/120)。我院每年为100多例患者实施PEG/PEJ置管,因科室侧重点不同,临床护士对于PEG/PEJ管的护理水平参差不齐。为降低导管相关并发症、确保治疗顺利进行,我院从2012年成立PEG/PEJ管护理会诊小组,工作内容涵盖PEG/PEJ管的护理、营养支持的护理等,收到了很好的效果。现将 PEG/PEJ管护理会诊的做法与体会报告如下。
Synthesis and Photochromism of Novel Spiro(indoline-2,3'-naphtho[2,l-b][1,4]oxazine)

A series of novel spirooxazine(SPO) derivatives containing nitrogen heterocycles was synthesized and characterized by ~1H NMR spectra, Fourier transform infrared(FTIR) spectra, mass spectra(MS) and elemental analysis, and their photochromic behaviors were fully investigated in solvents and polymer media. In solvents, they displayed excellent photochromism properties such as high photochromic response and fast thermal bleaching rate. Especially, compounds 1 and 4 exhibited strong fluorescence intensities in dichloromethane solution. It was additionally found that compound 4 showed high fatigue resistence in poly(methyl methacrylate)(PMMA) film, and the thermal decay curves were fitted with biexponential function in PMMA film.
来曲唑治疗未绝经子宫肌瘤66例临床观察

目的探讨来曲唑治疗未经绝子宫肌瘤的临床效果。方法选取2011年10月至2013年6月上海市黄浦区妇幼保健院收治的66例未绝经子宫肌瘤患者,口服来曲唑2.5mg,每天1次,连续12周,不考虑月经周期。治疗前后超声测量子宫及瘤体体积,检查血常规及肝肾功能,检测血清激素水平,观察月经变化。结果治疗后子宫肌瘤体积由(85.1±23.4)cm~3减至(47.2±17.0)cm~3,子宫体积由(332.4±38.5)cm~3减至(236.8±34.1)cm~3,月经期由(11.3±2.3)d 缩短至(5.8±1.7)d,贫血程度得到改善,差异均有统计学意义(P<0.05)。4例出现轻微不良反应,肝肾功能及血清激素水平无明显改变。结论来曲唑治疗未绝经子宫肌瘤效果良好。