# Mitigating Psychological Trauma on Adult Burn Patients Based on Virtual Reality Technology of Smart Medical Treatment

Authors: Hongli Ren; Yunpeng Du; Xiaofen Feng; Jiamin Pu; Xiaoyan Xiang
Journal: Journal of Healthcare Engineering
 (2021)

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## Abstract

Virtual reality (VR) is one of the hot spots in the computer network world in recent years, which has attracted more and more people’s attention. This study mainly explores the effect of mitigating the psychological trauma of adult burn patients based on the VR technology of smart medical treatment. First, the EEG data are sent to the data processing module through a wireless protocol; then, the data processing module denoises the EEG data and performs feature extraction and feedback parameter calculation; after that, these parameters will be sent to the VR interaction engine; based on this, these parameters change the VR scene to capture and reflect the physiological activities of the patient’s brain in real time; finally, the patient uses the VR scene content presented by the real-time feedback of the captured EEG signal as a guide to making self-adjustment in time, and the electrical signal of captured brain at this time is again transmitted to the next work cycle and continues to feed back and present new VR interactive scenes to guide and intervene in the patient’s self-regulation behavior. The VR feedback training module is responsible for receiving the characteristic data calculated from the EEG acquisition and processing module and converts it into parameter variables that control the VR intervention system. The system user adjusts the state according to the feedback information displayed in the VR scene and generates new EEG signals to promote the realization of self-adjustment. The biofeedback training based on EEG feeds back the intuitive EEG state to the patient, prompting them to learn how to realize self-regulation and achieve the purpose of adjusting the level of mental health. The degree of itching and pain in the VR treatment group was alleviated, and compared with the normal training treatment results, it was statistically significant (P>0.05). This study has a positive effect on the psychological intervention of patients with facial injuries.


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## Body

## 1. Introduction

Burns are a common type of trauma in social life, especially in wartime. Not only will it cause severe physical damage to the patient, resulting in impaired physical function, scar hyperplasia, wound pain, sleep disturbance, and so on, but also it will cause the patient to form a certain psychological trauma, produce social communication barriers, greatly reduce social adaptability, and so on. It may even lead to mental disorders.In recent years, medical technology related to burn treatment and rehabilitation has received a lot of capital and manpower investment, and more and more burn patients have been cured of their physical trauma and returned to society. However, burns not only are physical trauma but also cause great psychological damage. Dysfunction, disfigurement, or even physical disability caused by long-term scar contracture during treatment can easily cause psychological disorders in the patient’s mood, behavior, and cognition and make patient prone to anxiety, depression, tension, fear, sleep disorders, and social avoidance, discrimination, shame, abandonment, and self-burden.The success of immersive virtual reality (VR) experiences depends on solving numerous challenges across multiple disciplines. Bastug et al. emphasized the importance of VR technology as a disruptive use case for 5G (and beyond). In addition, they studied three VR case studies and provided numerical results under various storage, computing, and network configurations. Although they revealed the limitations of the current network and provided reasons for more theories and for the public to take the lead in VR innovation, research is still lacking in practice [1]. Patney et al. believe that recessed rendering can synthesize images, so that the details of the image outside the eye movement area are gradually reduced. They designed an eccentric rendering user study to evaluate the perception of human peripheral vision when viewing today’s displays. After verifying these insights on desktops and head-mounted displays, with the help of high-speed gaze tracking, they designed a perceptible target image to design and produce a centralized renderer. Although they designed a practical recessed rendering system, they did not verify its performance [2]. Sharar et al. believe that immersive VR dispersion therapy can effectively relieve pain clinically. 74 healthy volunteers received a standard 18-minute multimodal pain sequence (alternating thermal stimulation and distal stimulation) while undergoing immersive interactive VR distraction. The subjects used a 0–10-graphic rating scale to score their subjective pain intensity and entertainment, and a 9-point scale to score their emotional and arousal state. Although the immersive VR distraction in his study significantly reduced the subjective pain intensity, its negative effects are unknown [3]. Freeman believes that, with VR and computer-generated interactive environments, individuals can repeatedly experience the problems they encounter and learn how to overcome difficulties through evidence-based psychotherapy. He conducted a systematic review of empirical research. His research found that treatment based on VR exposure can reduce anxiety, but there is a lack of promising research and treatment approaches [4].First, the EEG data are sent to the data processing module through a wireless protocol; then, the data processing module denoises the EEG data and performs feature extraction and feedback parameter calculation; after that, these parameters will be sent to the VR interaction engine; based on this, these parameters change the VR scene to capture and reflect the physiological activities of the patient’s brain in real time; finally, the patient uses the VR scene content presented by the real-time feedback of the captured EEG signal as a guide to making self-adjustment in time, and the electrical signal of captured brain at this time is again transmitted to the next work cycle and continues to feed back and present new VR interactive scenes to guide and intervene in the patient’s self-regulation behavior. The VR feedback training module is responsible for receiving the characteristic data calculated from the EEG acquisition and processing module and converts it into parameter variables that control the VR intervention system.


## 2. Mental Trauma Counseling

### 2.1. Psychological Trauma

The similarity of posttraumatic stress disorder is that they are sudden and unexpected, which will cause shock to the injured and prone to strong stress response [5, 6]. The difference is that burns can cause scar hyperplasia and severe damage to functions such as perspiration. At the same time, the wounds formed by burns are painful, which can cause severe insomnia and anxiety. On the other hand, the rehabilitation of burn patients is persistent and repetitive. Including wound treatment and repair, burn skin repair, and body function rehabilitation, the recovery time will take several years or even a lifetime [7]. Therefore, it will cause greater psychological pressure on the injured and their families and even mental illness [8, 9].The short-term energy calculation of the emotional speech signal at timen is defined as follows:(1)En=∑m=−∞∞xm⋅wn−m2.Among them,En is the energy value [10].Adult posttraumatic stress disorder will have the following manifestations: self-blame and self-blame behaviors, belief changes, mood disorders, somatization symptoms, and self-harm behaviors [11, 12]. Witnessing a bloody death or the sudden death of a loved one is an event that the normal psychological defense mechanism of adults cannot cope with. Adults will feel shocked and out of control, and they may have a posttraumatic stress response. It is a normal reaction, but if the symptoms exist for a long time, it can be diagnosed as posttraumatic stress disorder according to professional diagnostic standards [13]. In fact, psychological trauma has strong comorbidity, and it is often diagnosed as depression and so on. There are not many people who are really diagnosed with posttraumatic stress disorder [14, 15]. Caregivers of traumatized adults have difficulty in identifying the child’s psychological changes in time and providing support for them. It is often that the child’s emotions and behaviors have changed after a long time has passed since the traumatic event [16]. The process of posttraumatic cognition, coping, and stress is shown in Figure 1 [17, 18].Figure 1
Posttraumatic cognition, coping, and stress process.


### 2.2. VR Technology

VR technology is a new product of the development and integration of computer image processing, simulation, sensing, network, and artificial intelligence [19]. The idea of VR first appeared in science fiction, specifically referring to some worlds without boundaries and constraints that do not exist in real life, which can be changed according to people’s wishes. VR technology first appeared in the 1960s, and some researches began to try to simulate virtual scenes with television equipment, but due to the constraints of electronic equipment at that time, it was impossible to construct a true VR [20, 21].At present, according to the degree of integration and interaction between the simulated virtual world and the real world, VR technology can be subdivided into VR, focusing on simulating real scenes, allowing users to be unable to simulate real scenes and computer simulations of the three-dimensional virtual world for screening (representative equipment is Oculus); augmented reality (AR), also called mixed reality (representative equipment is Microsoft HoloLens); mixed reality (mix reality, MR), which combines the physical parameters in the VR world with the physical parameters in the real world. Features are matched, integrated, and interacted in real time. Its biggest feature is that it can provide more dimensional and real-world interaction possibilities for the virtual world. The representative device is Magic Leap [22].(2)PrC≥1−qppkqH11−qatt2l1−qscqH2+qH32lε,where PrC is the total amount of data transmission [23, 24].(3)Wi,j=expαiDHOL−x1+x,Ec=1L∑i=0l−1yk−i−ymk−i2+ymk−i,where Wij represents the final delayed power [25].VR technology uses the Bio Master virtual scene interactive evaluation and sports training system for training, which includes hardware and software. The hardware system is mainly composed of computers, sensors, displays, and wireless Bluetooth receiving systems. The computer-generated virtual environment is displayed on the display. The patient wears a wireless position sensor for motion capture. The patient can be immersed in a variety of different virtual environments. The state of motor function carries out targeted motor control training. The virtual training system can score and reward feedback and record in the virtual environment according to the situation of the affected upper limbs completing the corresponding actions. Occupational therapists formulate targeted and personalized VR training programs for patients through the evaluation results. Through this virtual technology, the patient’s participation is greatly improved, the immersion, interaction, and conception during training are increased, the patient’s motor function is greatly improved, and the patient’s cognitive level is improved [26].


### 2.3. Feature Extraction and Selection

The absolute power is a value used to calculate the absolute value of the brain electrical power.(4)AP=10logP.Among them,P represents the power value of brain electricity. The relative power is used to calculate the ratio of the absolute value of the EEG power to the carrier frequency output power carrier.(5)RP=10logPCarrier.For any spectrumUf,t, there are(6)fc,t=∫−∞∞fUf,tdf∫−∞∞Uf,tdf,σt2=∫−∞∞f−fc,t2Uf,tdf∫−∞∞Uf,tdf.The center frequency is used in research related to EEG and memory. The absolute center frequency is used to calculate the value of the absolute center frequency of the EEG signal.(7)ACF=CFα−CFb.Among them,CF represents the center frequency of α point. The relative center frequency is used to calculate the value of the EEG signal relative to the center frequency.(8)RCF=CFα−CFb.The slope is used to calculate the value of the slope of the EEG signal.(9)Slope=tanα=hd×100%.The brain waves of nearby pixels generally have a high degree of spatial correlation. That is, adjacent pixels with similar attributes are divided into classes with the same probability. The spatial information of image segmentation is very important, but it means that traditional algorithms do not need to consider the spatial correlation of blurred pixels.(10)Jm=∑i=1c∑j=1Nuijmxj−vi2+αNR∑i=1c∑j=1Nuijmxr−vi2.Among them,N is a pixel, indicating the number of pixels contained nearby. The fuzzy membership function of each pixel of the matrix is independent.(11)minJU,V=min∑i=1n∑k=1cuikmdik2=∑i=1nmin∑k=1cuikmdik2.The constraints of the above extreme values are(12)∑k=1cμik=1.The kurtosis value of the EEG signal is(13)KurtX=EX−μσ4=EX−μ4EX−μ22,where X represents the brain electrical signal [27].


## 2.1. Psychological Trauma

The similarity of posttraumatic stress disorder is that they are sudden and unexpected, which will cause shock to the injured and prone to strong stress response [5, 6]. The difference is that burns can cause scar hyperplasia and severe damage to functions such as perspiration. At the same time, the wounds formed by burns are painful, which can cause severe insomnia and anxiety. On the other hand, the rehabilitation of burn patients is persistent and repetitive. Including wound treatment and repair, burn skin repair, and body function rehabilitation, the recovery time will take several years or even a lifetime [7]. Therefore, it will cause greater psychological pressure on the injured and their families and even mental illness [8, 9].The short-term energy calculation of the emotional speech signal at timen is defined as follows:(1)En=∑m=−∞∞xm⋅wn−m2.Among them,En is the energy value [10].Adult posttraumatic stress disorder will have the following manifestations: self-blame and self-blame behaviors, belief changes, mood disorders, somatization symptoms, and self-harm behaviors [11, 12]. Witnessing a bloody death or the sudden death of a loved one is an event that the normal psychological defense mechanism of adults cannot cope with. Adults will feel shocked and out of control, and they may have a posttraumatic stress response. It is a normal reaction, but if the symptoms exist for a long time, it can be diagnosed as posttraumatic stress disorder according to professional diagnostic standards [13]. In fact, psychological trauma has strong comorbidity, and it is often diagnosed as depression and so on. There are not many people who are really diagnosed with posttraumatic stress disorder [14, 15]. Caregivers of traumatized adults have difficulty in identifying the child’s psychological changes in time and providing support for them. It is often that the child’s emotions and behaviors have changed after a long time has passed since the traumatic event [16]. The process of posttraumatic cognition, coping, and stress is shown in Figure 1 [17, 18].Figure 1
Posttraumatic cognition, coping, and stress process.


## 2.2. VR Technology

VR technology is a new product of the development and integration of computer image processing, simulation, sensing, network, and artificial intelligence [19]. The idea of VR first appeared in science fiction, specifically referring to some worlds without boundaries and constraints that do not exist in real life, which can be changed according to people’s wishes. VR technology first appeared in the 1960s, and some researches began to try to simulate virtual scenes with television equipment, but due to the constraints of electronic equipment at that time, it was impossible to construct a true VR [20, 21].At present, according to the degree of integration and interaction between the simulated virtual world and the real world, VR technology can be subdivided into VR, focusing on simulating real scenes, allowing users to be unable to simulate real scenes and computer simulations of the three-dimensional virtual world for screening (representative equipment is Oculus); augmented reality (AR), also called mixed reality (representative equipment is Microsoft HoloLens); mixed reality (mix reality, MR), which combines the physical parameters in the VR world with the physical parameters in the real world. Features are matched, integrated, and interacted in real time. Its biggest feature is that it can provide more dimensional and real-world interaction possibilities for the virtual world. The representative device is Magic Leap [22].(2)PrC≥1−qppkqH11−qatt2l1−qscqH2+qH32lε,where PrC is the total amount of data transmission [23, 24].(3)Wi,j=expαiDHOL−x1+x,Ec=1L∑i=0l−1yk−i−ymk−i2+ymk−i,where Wij represents the final delayed power [25].VR technology uses the Bio Master virtual scene interactive evaluation and sports training system for training, which includes hardware and software. The hardware system is mainly composed of computers, sensors, displays, and wireless Bluetooth receiving systems. The computer-generated virtual environment is displayed on the display. The patient wears a wireless position sensor for motion capture. The patient can be immersed in a variety of different virtual environments. The state of motor function carries out targeted motor control training. The virtual training system can score and reward feedback and record in the virtual environment according to the situation of the affected upper limbs completing the corresponding actions. Occupational therapists formulate targeted and personalized VR training programs for patients through the evaluation results. Through this virtual technology, the patient’s participation is greatly improved, the immersion, interaction, and conception during training are increased, the patient’s motor function is greatly improved, and the patient’s cognitive level is improved [26].


## 2.3. Feature Extraction and Selection

The absolute power is a value used to calculate the absolute value of the brain electrical power.(4)AP=10logP.Among them,P represents the power value of brain electricity. The relative power is used to calculate the ratio of the absolute value of the EEG power to the carrier frequency output power carrier.(5)RP=10logPCarrier.For any spectrumUf,t, there are(6)fc,t=∫−∞∞fUf,tdf∫−∞∞Uf,tdf,σt2=∫−∞∞f−fc,t2Uf,tdf∫−∞∞Uf,tdf.The center frequency is used in research related to EEG and memory. The absolute center frequency is used to calculate the value of the absolute center frequency of the EEG signal.(7)ACF=CFα−CFb.Among them,CF represents the center frequency of α point. The relative center frequency is used to calculate the value of the EEG signal relative to the center frequency.(8)RCF=CFα−CFb.The slope is used to calculate the value of the slope of the EEG signal.(9)Slope=tanα=hd×100%.The brain waves of nearby pixels generally have a high degree of spatial correlation. That is, adjacent pixels with similar attributes are divided into classes with the same probability. The spatial information of image segmentation is very important, but it means that traditional algorithms do not need to consider the spatial correlation of blurred pixels.(10)Jm=∑i=1c∑j=1Nuijmxj−vi2+αNR∑i=1c∑j=1Nuijmxr−vi2.Among them,N is a pixel, indicating the number of pixels contained nearby. The fuzzy membership function of each pixel of the matrix is independent.(11)minJU,V=min∑i=1n∑k=1cuikmdik2=∑i=1nmin∑k=1cuikmdik2.The constraints of the above extreme values are(12)∑k=1cμik=1.The kurtosis value of the EEG signal is(13)KurtX=EX−μσ4=EX−μ4EX−μ22,where X represents the brain electrical signal [27].


## 3. Mental Trauma Counseling Experiment

### 3.1. Research Objects and Grouping Standards

The method of convenience sampling is adopted to conduct research based on the burn center and recruit patients who voluntarily participate in the hospitalization period from January 2018 to November 2020.Inclusion criteria are as follows:(1)
Age > 18 years old.(2)
The cause of burns is hydrothermal (water, oil, soup, etc.), steam, high-temperature gas, flame, hot metal liquid or solid, electricity, chemical substances, and so on.(3)
Using the classification method discussed and approved by the National Burn Conference in 1970, diagnosed as a burn patient of II and above.(4)
In the stage of burn rehabilitation.(5)
A clear consciousness, with reading and no recognition results, able to cooperate with investigations.(6)
Informed consent and voluntary participation in research.Research grouping: random allocation software was used to group. On the basis of conventional rehabilitation training, the observation group was given conventional treatment, and the control group was given conventional treatment + VR technology.


### 3.2. EEG Feedback Depression Intervention Framework Based on VR

VR technology is highly interactive, allowing patients to immerse themselves in VR scenes for effective intervention. The framework designed in this chapter is suitable for the patient’s EEG signal data obtained by the universal three-lead EEG collector. First, the EEG data are sent to the data processing module through a wireless protocol; then, the data processing module denoises the EEG data and performs feature extraction and feedback parameter calculation; after that, these parameters will be sent to the VR interaction engine; based on this, these parameters change the VR scene to capture and reflect the physiological activities of the patient’s brain in real time; finally, the patient uses the VR scene content presented by the real-time feedback of the captured EEG signal as a guide to making self-adjustment in time, and the electrical signal of captured brain at this time is again transmitted to the next work cycle and continues to feed back and present new VR interactive scenes to guide and intervene in the patient’s self-regulation behavior. The specific workflow is described as follows:Data processing: The incoming EEG data need to be denoised. First, we use a band-pass wave filter to eliminate the environmental noise generated by the power line or bypass electronic equipment in the EEG data. At the same time, since the electrodeposition of our EEG collector is located in the prefrontal lobe, the collected EEG data also need to adopt discrete wavelet transform and an improved adaptive noise elimination algorithm to eliminate ocular signal pollution. Subsequently, we divided dozens of features including relative power, absolute power, center frequency, relative center frequency asymmetry, absolute center frequency asymmetry, relative power asymmetry, and absolute power asymmetry of the four most commonly used extracted from brain waves which are alpha (8–15 Hz) wave, beta (16–31 Hz) wave, gamma (> 32 Hz) wave, and theta (4–7 Hz) wave. Finally, the feedback parameters calculated from these features will be transmitted to the VR interactive scene.VR interactive scene: It includes two independent input parameters. One includes basic information parameters such as the patient’s gender, age, and medical background. The other is responsible for outputting the calculated feedback parameters. The VR interactive scene combines the two parts of parameters in real time to select and generate the VR interactive scene. The patient feels the VR scene and interacts with the scene content in real time by wearing a VR helmet, adjusts the state by means of deep breathing, scene imagination, and other methods, and regulates the brain activity in an active way to improve the mental state. At this time, the EEG data of the patient will also change accordingly, and the EEG data will be recollected by the EEG collector and then enter the next cycle. We divide each intervention into two to three VR interactive scenes with a length of about 10 minutes. During the intervention, the doctor or patient can select and switch between different VR interactive scenes according to the degree of depression of the patient to ensure that the intervention achieves the best effect. In addition, the system generates a report after each intervention to help doctors evaluate patients.Data storage: All EEG data obtained during the intervention are stored in the data storage system. On the one hand, it is convenient for doctors to carry out long-term monitoring and evaluation of the patient’s rehabilitation process; on the other hand, it can expand the size of the EEG database in a timely and effective manner, which will not only help us to discover new EEG biofeedback characteristics of depression but also help us to continuously optimize the current feedback algorithm. The framework of EEG bioinformation feedback depression intervention based on VR is shown in Figure2.Figure 2
The framework of EEG bioinformation feedback depression intervention based on VR.


### 3.3. EEG Acquisition and Processing

This module is responsible for receiving the electrical signal data from the EEG acquisition equipment, passing the EEG signal to the VR feedback training module through preprocessing, feature extraction, and feedback parameter calculation. The universal three-lead EEG sensor (Figures 3-2) used in this system is connected to a personal computer PC via Bluetooth protocol. After Bluetooth pairing, the EEG acquisition and processing module issues instructions and transmits data. The data received by the computer use the 3-byte hexadecimal “A03024” as the start tag of each piece of data and end with the 1-byte “C0” tag. Between the start mark and the end mark are the EEG signal data collected by Fp1, Fpz, and Fp2 electrodepositions. Each lead is 8 bytes each time. The sampling rate of the EEG sensor is 250 Hz, which can transmit the signal back to the EEG acquisition and processing module in real time, so the system receives 250 sets of data links per second.Due to the high sampling frequency of EEG sensors and the limited processing capacity of ordinary personal computers, how to choose a reasonable data segmentation window will directly determine the data processing delay of the feedback system. On the premise of ensuring that, both the computer’s data processing efficiency and the effective feedback of the training status of the intervention object can be taken into account. We finally chose to use every 4 seconds as the analysis window of a piece of data, that is, to calculate the feedback feature once with 1000 data points. At the same time, in order to avoid the edge of the cutting window falling on the center of the characteristic waveform and increase the smoothness of the feedback effect, we choose to set a 2-second overlap between each window.


### 3.4. VR Feedback Training

This module is responsible for receiving the characteristic data calculated from the EEG acquisition and processing module and converts it to parameter variables that control the VR intervention system. The system user adjusts the state according to the feedback information displayed in the VR scene and generates new EEG signals to promote the realization of self-adjustment. And these signals will be collected by the three-lead EEG equipment and enter the next cycle. The biofeedback training based on EEG feeds back the intuitive EEG state to the patient, prompting them to learn how to realize self-regulation and achieve the purpose of adjusting the level of mental health.Based on the training of positive emotional stimulation in VR “cinema scene,” patients with depression experience audio and video that can produce positive emotional stimulation in immersive VR scenes. Set the feedback parameter f2, the beta wave at the prefrontal lobe point increases, and the beta wave imbalance in the left and right brain areas increases. At this time, real-time feedback can reduce the absolute power of the beta wave at Fp1; the feedback index is normalized to −1 to 1. Between the decimals, the mapping controls the following parameters in the VR scene:(1)
The status indicator bar in the scene changes according to the status and is divided into 5 different levels, followed by green, yellow, and red.(2)
The overall environment in the VR interactive scene will be adjusted according to the quality of the real-time feedback value, which is divided into 5 different levels, which are clear, slightly blurred, and severely blurred.(3)
The volume of the background concert in the VR scene is adjusted according to the quality of the real-time feedback value, which is divided into 5 different levels, followed by moderate volume, lighter, and very light.Relaxation training is based on VR; patients with depression are immersed in a VR forest scene accompanied by soft music. The training goal is to let the patient relax further to achieve the effect of relieving stress. Set the feedback parameter fz to reduce the relative center of gravity frequency of theta wave at Fp1 and increase the relative center of gravity frequency of the gamma wave at Fp2; the feedback index is normalized to a decimal between −1 and 1, and the following parameters in the VR scene are mapped and controlled:(1)
The status indicator bar in the scene changes according to the status and is divided into 5 different levels, followed by green, yellow, and red periods.(2)
The light and dark level of the overall environment in the VR scene will change according to the quality of the feedback value, which is divided into 5 different levels, which are bright, dim, and dim in order.(3)
The volume of the background concert in the VR scene is adjusted according to the quality of the feedback value, which is divided into 5 different levels, followed by moderate volume, lighter, and very light.


### 3.5. Psychological Trauma Treatment Effect Score

#### 3.5.1. Depression Score

The Hamilton Depression (HAMD) scale was used to evaluate the depression of patients, divided into mild, moderate, and severe depression.


#### 3.5.2. Customer Satisfaction

Service evaluation uses questionnaire surveys to understand the client’s and his wife’s satisfaction with this casework service, including satisfaction with social workers’ service attitude and ability and satisfaction with service results. The social worker is responsible for the design, distribution, and recovery of the accountability questionnaire and records and analyzes the survey results. Two questionnaires were distributed and two were recovered. In this process, social workers will strictly abide by the relevant principles and regulations of the questionnaire survey, maintain value neutrality, and conduct objective records and analysis.


## 3.1. Research Objects and Grouping Standards

The method of convenience sampling is adopted to conduct research based on the burn center and recruit patients who voluntarily participate in the hospitalization period from January 2018 to November 2020.Inclusion criteria are as follows:(1)
Age > 18 years old.(2)
The cause of burns is hydrothermal (water, oil, soup, etc.), steam, high-temperature gas, flame, hot metal liquid or solid, electricity, chemical substances, and so on.(3)
Using the classification method discussed and approved by the National Burn Conference in 1970, diagnosed as a burn patient of II and above.(4)
In the stage of burn rehabilitation.(5)
A clear consciousness, with reading and no recognition results, able to cooperate with investigations.(6)
Informed consent and voluntary participation in research.Research grouping: random allocation software was used to group. On the basis of conventional rehabilitation training, the observation group was given conventional treatment, and the control group was given conventional treatment + VR technology.


## 3.2. EEG Feedback Depression Intervention Framework Based on VR

VR technology is highly interactive, allowing patients to immerse themselves in VR scenes for effective intervention. The framework designed in this chapter is suitable for the patient’s EEG signal data obtained by the universal three-lead EEG collector. First, the EEG data are sent to the data processing module through a wireless protocol; then, the data processing module denoises the EEG data and performs feature extraction and feedback parameter calculation; after that, these parameters will be sent to the VR interaction engine; based on this, these parameters change the VR scene to capture and reflect the physiological activities of the patient’s brain in real time; finally, the patient uses the VR scene content presented by the real-time feedback of the captured EEG signal as a guide to making self-adjustment in time, and the electrical signal of captured brain at this time is again transmitted to the next work cycle and continues to feed back and present new VR interactive scenes to guide and intervene in the patient’s self-regulation behavior. The specific workflow is described as follows:Data processing: The incoming EEG data need to be denoised. First, we use a band-pass wave filter to eliminate the environmental noise generated by the power line or bypass electronic equipment in the EEG data. At the same time, since the electrodeposition of our EEG collector is located in the prefrontal lobe, the collected EEG data also need to adopt discrete wavelet transform and an improved adaptive noise elimination algorithm to eliminate ocular signal pollution. Subsequently, we divided dozens of features including relative power, absolute power, center frequency, relative center frequency asymmetry, absolute center frequency asymmetry, relative power asymmetry, and absolute power asymmetry of the four most commonly used extracted from brain waves which are alpha (8–15 Hz) wave, beta (16–31 Hz) wave, gamma (> 32 Hz) wave, and theta (4–7 Hz) wave. Finally, the feedback parameters calculated from these features will be transmitted to the VR interactive scene.VR interactive scene: It includes two independent input parameters. One includes basic information parameters such as the patient’s gender, age, and medical background. The other is responsible for outputting the calculated feedback parameters. The VR interactive scene combines the two parts of parameters in real time to select and generate the VR interactive scene. The patient feels the VR scene and interacts with the scene content in real time by wearing a VR helmet, adjusts the state by means of deep breathing, scene imagination, and other methods, and regulates the brain activity in an active way to improve the mental state. At this time, the EEG data of the patient will also change accordingly, and the EEG data will be recollected by the EEG collector and then enter the next cycle. We divide each intervention into two to three VR interactive scenes with a length of about 10 minutes. During the intervention, the doctor or patient can select and switch between different VR interactive scenes according to the degree of depression of the patient to ensure that the intervention achieves the best effect. In addition, the system generates a report after each intervention to help doctors evaluate patients.Data storage: All EEG data obtained during the intervention are stored in the data storage system. On the one hand, it is convenient for doctors to carry out long-term monitoring and evaluation of the patient’s rehabilitation process; on the other hand, it can expand the size of the EEG database in a timely and effective manner, which will not only help us to discover new EEG biofeedback characteristics of depression but also help us to continuously optimize the current feedback algorithm. The framework of EEG bioinformation feedback depression intervention based on VR is shown in Figure2.Figure 2
The framework of EEG bioinformation feedback depression intervention based on VR.


## 3.3. EEG Acquisition and Processing

This module is responsible for receiving the electrical signal data from the EEG acquisition equipment, passing the EEG signal to the VR feedback training module through preprocessing, feature extraction, and feedback parameter calculation. The universal three-lead EEG sensor (Figures 3-2) used in this system is connected to a personal computer PC via Bluetooth protocol. After Bluetooth pairing, the EEG acquisition and processing module issues instructions and transmits data. The data received by the computer use the 3-byte hexadecimal “A03024” as the start tag of each piece of data and end with the 1-byte “C0” tag. Between the start mark and the end mark are the EEG signal data collected by Fp1, Fpz, and Fp2 electrodepositions. Each lead is 8 bytes each time. The sampling rate of the EEG sensor is 250 Hz, which can transmit the signal back to the EEG acquisition and processing module in real time, so the system receives 250 sets of data links per second.Due to the high sampling frequency of EEG sensors and the limited processing capacity of ordinary personal computers, how to choose a reasonable data segmentation window will directly determine the data processing delay of the feedback system. On the premise of ensuring that, both the computer’s data processing efficiency and the effective feedback of the training status of the intervention object can be taken into account. We finally chose to use every 4 seconds as the analysis window of a piece of data, that is, to calculate the feedback feature once with 1000 data points. At the same time, in order to avoid the edge of the cutting window falling on the center of the characteristic waveform and increase the smoothness of the feedback effect, we choose to set a 2-second overlap between each window.


## 3.4. VR Feedback Training

This module is responsible for receiving the characteristic data calculated from the EEG acquisition and processing module and converts it to parameter variables that control the VR intervention system. The system user adjusts the state according to the feedback information displayed in the VR scene and generates new EEG signals to promote the realization of self-adjustment. And these signals will be collected by the three-lead EEG equipment and enter the next cycle. The biofeedback training based on EEG feeds back the intuitive EEG state to the patient, prompting them to learn how to realize self-regulation and achieve the purpose of adjusting the level of mental health.Based on the training of positive emotional stimulation in VR “cinema scene,” patients with depression experience audio and video that can produce positive emotional stimulation in immersive VR scenes. Set the feedback parameter f2, the beta wave at the prefrontal lobe point increases, and the beta wave imbalance in the left and right brain areas increases. At this time, real-time feedback can reduce the absolute power of the beta wave at Fp1; the feedback index is normalized to −1 to 1. Between the decimals, the mapping controls the following parameters in the VR scene:(1)
The status indicator bar in the scene changes according to the status and is divided into 5 different levels, followed by green, yellow, and red.(2)
The overall environment in the VR interactive scene will be adjusted according to the quality of the real-time feedback value, which is divided into 5 different levels, which are clear, slightly blurred, and severely blurred.(3)
The volume of the background concert in the VR scene is adjusted according to the quality of the real-time feedback value, which is divided into 5 different levels, followed by moderate volume, lighter, and very light.Relaxation training is based on VR; patients with depression are immersed in a VR forest scene accompanied by soft music. The training goal is to let the patient relax further to achieve the effect of relieving stress. Set the feedback parameter fz to reduce the relative center of gravity frequency of theta wave at Fp1 and increase the relative center of gravity frequency of the gamma wave at Fp2; the feedback index is normalized to a decimal between −1 and 1, and the following parameters in the VR scene are mapped and controlled:(1)
The status indicator bar in the scene changes according to the status and is divided into 5 different levels, followed by green, yellow, and red periods.(2)
The light and dark level of the overall environment in the VR scene will change according to the quality of the feedback value, which is divided into 5 different levels, which are bright, dim, and dim in order.(3)
The volume of the background concert in the VR scene is adjusted according to the quality of the feedback value, which is divided into 5 different levels, followed by moderate volume, lighter, and very light.


## 3.5. Psychological Trauma Treatment Effect Score

### 3.5.1. Depression Score

The Hamilton Depression (HAMD) scale was used to evaluate the depression of patients, divided into mild, moderate, and severe depression.


### 3.5.2. Customer Satisfaction

Service evaluation uses questionnaire surveys to understand the client’s and his wife’s satisfaction with this casework service, including satisfaction with social workers’ service attitude and ability and satisfaction with service results. The social worker is responsible for the design, distribution, and recovery of the accountability questionnaire and records and analyzes the survey results. Two questionnaires were distributed and two were recovered. In this process, social workers will strictly abide by the relevant principles and regulations of the questionnaire survey, maintain value neutrality, and conduct objective records and analysis.


## 3.5.1. Depression Score

The Hamilton Depression (HAMD) scale was used to evaluate the depression of patients, divided into mild, moderate, and severe depression.


## 3.5.2. Customer Satisfaction

Service evaluation uses questionnaire surveys to understand the client’s and his wife’s satisfaction with this casework service, including satisfaction with social workers’ service attitude and ability and satisfaction with service results. The social worker is responsible for the design, distribution, and recovery of the accountability questionnaire and records and analyzes the survey results. Two questionnaires were distributed and two were recovered. In this process, social workers will strictly abide by the relevant principles and regulations of the questionnaire survey, maintain value neutrality, and conduct objective records and analysis.


## 4. Psychological Trauma Counseling

### 4.1. Influencing Factors on the Trend of Quality of Life

In order to explore the influencing factors of the change trend of the quality of life of burn patients, disability acceptance was used as a covariate for time changes, gender, burn cause, severity of illness, and whether there were complications, payment method, and education level as a constant time covariate. Secondary growth model: the results show that the conditional model fits the data well:P<0.001, CFI = 0.987, TLI = 0.978, RMSEA = 0.074, and SRMR = 0.025. The predictive effect of the covariates suggests that gender, burn reason, payment method, and education level have no effect on the intercept and slope factors of the quality of life of burn patients (P>0.05), while regarding the severity of the disease and whether there are complications in the intercept, the factors were −10721 and 5.522 (P<0.001), indicating that the more severe the disease, the lower the initial quality of life of patients with complications, and the difference in the rate of change of the quality of life between the two was not statistically significant (P>0.05). The influence of covariates on the trajectory of life quality changes is shown in Table 1. The impact of disability acceptance on the quality of life of burn patients is shown in Table 2. The analysis of the influence of covariates on the trajectory of life quality changes is shown in Figure 3. Figure 4 shows the impact of disability acceptance on the quality of life of burn patients.Table 1
The influence of covariates on the trajectory of quality of life.
ValueParameterEstimated valueStandard errorTPGenderIntercept−0.1212.662−0.0450.964Slope−00190.2580.073D.942Causes of burnsIntercept−0.4690.3100.5800.562Slope−0.0670 0790.8540.393SeverityIntercept−10.7211.721−6.229<0.001Slope0.1260.1750.7190.472ComplicationsIntercept5.5222.7931 9770.048Slope0.5080.2741 8570.063Payment methodsIntercept0.1170.8590.1360 892Slope−0.0410.083−0.4980.619Education levelIntercept0.351.1160.3140.754Slope−0.1180.109−1.0780.281Table 2
The impact of disability acceptance on the quality of life of burn patients.
TimeParameterRegression coefficientTPADS (at discharge)BSHS (upon discharge)0.61618.874<0.001ADS (1 month after hospital)BSHS (1 month after hospital)0.66921.660<0.001ADS (3 months after hospital)BSHS (3 months after hospital)0.68122.824<0.001ADS (6 months after hospital)BSHS (6 months after hospital)0.67822.123<0.001Figure 3
Analysis of the influence of covariates on the trajectory of quality of life.Figure 4
Analysis of the impact of disability acceptance on the quality of life of burn patients.


### 4.2. Adverse Reactions during Treatment

The adverse reactions during the treatment are shown in Table3. During the course of this study, none of the two groups had serious adverse reactions. In the observation group, the main manifestations were dizziness (2 cases), sleep disturbance (1 case), nausea (1 case), and neck discomfort (1 case); in the control group, the main manifestations were dizziness (1 case) and headache (1 case), Inattention (1 case), and anxiety (1 case); during and after the treatment, none of the study subjects had depression. The study found that patients can tolerate the above adverse reactions, and the above adverse reactions do not require special treatment and usually resolve by themselves within a few hours. The results of adverse reaction analysis are shown in Figure 5.Table 3
Adverse reactions during treatment.
SymptomGroupObservation group (n = 55)VR group (n = 53)PDizziness2 (3.6)1 (1.8)0.36Insomnia1 (1.8)00.51Nausea1 (1.8)00.51Neck1 (1.8)00.51Pain01 (1.8)0.51Headache01 (1.8)0.51Inattention01 (1.8)0.51Figure 5
Adverse reaction analysis results.


### 4.3. Comparative Analysis before and after Treatment in the VR Treatment Group

Comparison before and after treatment in the VR treatment group, after 8 weeks of treatment, shows that the difference in the processing speed of the VR treatment group compared with the baseline was statistically significant (P<0.05), while the increase in semantic fluency compared with the baseline score was not statistically significant, academic significance (P>0.05), the number sequence contained in working memory is higher than the baseline score before treatment, and the difference is not statistically significant (P>0.05). The executive ability in the subscale includes an increase in the continuous operation score, and the difference is also statistically significant (P<0.05). The social cognition is higher than the baseline score, and the difference is also statistically significant (P<0.05). The baseline score increased, and the difference was not statistically significant (P>0.05). Part of the analysis results of the VR treatment group are shown in Figure 6. The 8-week treatment results are shown in Table 4.Figure 6
Partial analysis results of VR treatment group.Table 4
Eight-week treatment results.
Cognitive dimensionBaseline (30 cases)Week 8 (30 cases)TPConnect0.25 ± 0.020.27 ± 0.033.08< 0.05Semantic fluency17.33 ± 6.3518.68 ± 5.830.85> 0.05Symbol encoding32.73 ± 11.2140.14 ± 11.962.47< 0.05Number sequence14.82 ± 5.4316.15 ± 5.320.95> 0.05Spatial breadth11.76 ± 4.0214.25 ± 4.512.25< 0.05Continuous operation1.61 ± 0.732.02 ± 0.712.20< 0.05Verbal memory18.22 ± 5.0319.45 ± 4.860.96>0.05Visual memory13.92 ± 7.3318.16 ± 7.472.22< 0.05Maze1.72 ± 0.472.03 ± 0.552.34> 0.05Social cognition6.82 ± 1.858.43 ± 1.393.81< 0.05The wound pruritus and wound pain of the control group and the VR treatment group were compared on the 7th day, the 14th day, and the 28th day after treatment, as shown in Table5. The pruritus and pain in the VR treatment group were all reduced, and the test results of the two groups were all statistically significant (P>0.05). It shows that VR treatment has a certain effect on itching and pain. 30 days, 60 days, and 90 days after treatment, the hand wound scar formation and hand joint mobility scores of the two groups were compared. Discharged patients were recorded in the form of regular outpatient follow-up. Data analysis showed that the scar formation of patients in the VR treatment group was statistically significant (P>0.05) compared with the control group at 30 days, 60 days, and 90 days after treatment. VR treatment can significantly reduce the formation of early scars. Thirty days after treatment, the hand joint range of motion between the two groups was compared (P>0.05), and the results were not statistically significant. But after 60 days and 90 days of treatment, the two groups showed significant differences. The statistical results showed P<0.05, which was statistically significant. It shows that there is no significant difference in the range of motion of the hand joints in the early treatment, but significant differences can be seen after 2-3 months of treatment. VR treatment can effectively increase the range of motion after burns. The treatment effect is shown in Figure 7.Table 5
Comparison of wound pruritus and wound pain in the control group and the VR treatment group on the 7, 14, and 28 days after treatment.
Observation itemTime (days)Control group (points)Exercise therapy group (points)PItching73.16 ± 0.782.54 ± 0.750.027142.18 ± 0.661.87 ± 0.700.003282.11 ± 0.721.61 ± 0.12< 0.001Pain76.55 ± 1.584.20 ± 1.51< 0.001143.88 ± 1.221.20 ± 1.02< 0.001282.25 ± 1.061.11 ± 0.77< 0.001Epilepsy306.27 ± 2.073.85 ± 1.53< 0.001606.45 ± 1.993.78 ± 1.74< 0.001906.45 ± 2.173.76 ± 1.6< 0.001Hand joint mobility302.75 ± 0.813.02 ± 0.990.001602.43 ± 0.792.92 ± 0.670.001Figure 7
Treatment effect.In order to find the best brain wave feature that can represent the fear of heights, we compared the best classification of 4 different features. The accuracy of different features in different brain wave frequency bands is shown in Table6. From Table 6, we can know that the devolatility analysis can achieve the best accuracy rate of 86.87% in the entire frequency band, and the correlation between high-frequency waves (alpha, beta, and gamma) and emotions is higher than that of low-frequency waves (delta and theta). In addition, the results of randomly selected 20 groups of experimenters before and after the depression grade ratio are shown in Figure 8. It can be seen from Figure 8 that there are two groups of experimenters that have not changed much before and after treatment, and the other 18 groups have obvious changes before and after treatment. Therefore, in general, we believe that VR has a certain effect on treating depression after burns.Table 6
Accuracy of different features in different brainwave frequency bands.
FeatureBrain waves (%)DeltaThetaAlphaBetaGammaAllDevolatility59.5766.1368.3980.2381.9786 87Hurst index43.1945.4653.1062.7466.7975.06Squared difference61.7664.6967.7869.7670.7980.09Approximate entropy72.8973.6875.3874.1273.8 282.65Figure 8
Comparison of experimenters before and after depression.
(a)(b)


## 4.1. Influencing Factors on the Trend of Quality of Life

In order to explore the influencing factors of the change trend of the quality of life of burn patients, disability acceptance was used as a covariate for time changes, gender, burn cause, severity of illness, and whether there were complications, payment method, and education level as a constant time covariate. Secondary growth model: the results show that the conditional model fits the data well:P<0.001, CFI = 0.987, TLI = 0.978, RMSEA = 0.074, and SRMR = 0.025. The predictive effect of the covariates suggests that gender, burn reason, payment method, and education level have no effect on the intercept and slope factors of the quality of life of burn patients (P>0.05), while regarding the severity of the disease and whether there are complications in the intercept, the factors were −10721 and 5.522 (P<0.001), indicating that the more severe the disease, the lower the initial quality of life of patients with complications, and the difference in the rate of change of the quality of life between the two was not statistically significant (P>0.05). The influence of covariates on the trajectory of life quality changes is shown in Table 1. The impact of disability acceptance on the quality of life of burn patients is shown in Table 2. The analysis of the influence of covariates on the trajectory of life quality changes is shown in Figure 3. Figure 4 shows the impact of disability acceptance on the quality of life of burn patients.Table 1
The influence of covariates on the trajectory of quality of life.
ValueParameterEstimated valueStandard errorTPGenderIntercept−0.1212.662−0.0450.964Slope−00190.2580.073D.942Causes of burnsIntercept−0.4690.3100.5800.562Slope−0.0670 0790.8540.393SeverityIntercept−10.7211.721−6.229<0.001Slope0.1260.1750.7190.472ComplicationsIntercept5.5222.7931 9770.048Slope0.5080.2741 8570.063Payment methodsIntercept0.1170.8590.1360 892Slope−0.0410.083−0.4980.619Education levelIntercept0.351.1160.3140.754Slope−0.1180.109−1.0780.281Table 2
The impact of disability acceptance on the quality of life of burn patients.
TimeParameterRegression coefficientTPADS (at discharge)BSHS (upon discharge)0.61618.874<0.001ADS (1 month after hospital)BSHS (1 month after hospital)0.66921.660<0.001ADS (3 months after hospital)BSHS (3 months after hospital)0.68122.824<0.001ADS (6 months after hospital)BSHS (6 months after hospital)0.67822.123<0.001Figure 3
Analysis of the influence of covariates on the trajectory of quality of life.Figure 4
Analysis of the impact of disability acceptance on the quality of life of burn patients.


## 4.2. Adverse Reactions during Treatment

The adverse reactions during the treatment are shown in Table3. During the course of this study, none of the two groups had serious adverse reactions. In the observation group, the main manifestations were dizziness (2 cases), sleep disturbance (1 case), nausea (1 case), and neck discomfort (1 case); in the control group, the main manifestations were dizziness (1 case) and headache (1 case), Inattention (1 case), and anxiety (1 case); during and after the treatment, none of the study subjects had depression. The study found that patients can tolerate the above adverse reactions, and the above adverse reactions do not require special treatment and usually resolve by themselves within a few hours. The results of adverse reaction analysis are shown in Figure 5.Table 3
Adverse reactions during treatment.
SymptomGroupObservation group (n = 55)VR group (n = 53)PDizziness2 (3.6)1 (1.8)0.36Insomnia1 (1.8)00.51Nausea1 (1.8)00.51Neck1 (1.8)00.51Pain01 (1.8)0.51Headache01 (1.8)0.51Inattention01 (1.8)0.51Figure 5
Adverse reaction analysis results.


## 4.3. Comparative Analysis before and after Treatment in the VR Treatment Group

Comparison before and after treatment in the VR treatment group, after 8 weeks of treatment, shows that the difference in the processing speed of the VR treatment group compared with the baseline was statistically significant (P<0.05), while the increase in semantic fluency compared with the baseline score was not statistically significant, academic significance (P>0.05), the number sequence contained in working memory is higher than the baseline score before treatment, and the difference is not statistically significant (P>0.05). The executive ability in the subscale includes an increase in the continuous operation score, and the difference is also statistically significant (P<0.05). The social cognition is higher than the baseline score, and the difference is also statistically significant (P<0.05). The baseline score increased, and the difference was not statistically significant (P>0.05). Part of the analysis results of the VR treatment group are shown in Figure 6. The 8-week treatment results are shown in Table 4.Figure 6
Partial analysis results of VR treatment group.Table 4
Eight-week treatment results.
Cognitive dimensionBaseline (30 cases)Week 8 (30 cases)TPConnect0.25 ± 0.020.27 ± 0.033.08< 0.05Semantic fluency17.33 ± 6.3518.68 ± 5.830.85> 0.05Symbol encoding32.73 ± 11.2140.14 ± 11.962.47< 0.05Number sequence14.82 ± 5.4316.15 ± 5.320.95> 0.05Spatial breadth11.76 ± 4.0214.25 ± 4.512.25< 0.05Continuous operation1.61 ± 0.732.02 ± 0.712.20< 0.05Verbal memory18.22 ± 5.0319.45 ± 4.860.96>0.05Visual memory13.92 ± 7.3318.16 ± 7.472.22< 0.05Maze1.72 ± 0.472.03 ± 0.552.34> 0.05Social cognition6.82 ± 1.858.43 ± 1.393.81< 0.05The wound pruritus and wound pain of the control group and the VR treatment group were compared on the 7th day, the 14th day, and the 28th day after treatment, as shown in Table5. The pruritus and pain in the VR treatment group were all reduced, and the test results of the two groups were all statistically significant (P>0.05). It shows that VR treatment has a certain effect on itching and pain. 30 days, 60 days, and 90 days after treatment, the hand wound scar formation and hand joint mobility scores of the two groups were compared. Discharged patients were recorded in the form of regular outpatient follow-up. Data analysis showed that the scar formation of patients in the VR treatment group was statistically significant (P>0.05) compared with the control group at 30 days, 60 days, and 90 days after treatment. VR treatment can significantly reduce the formation of early scars. Thirty days after treatment, the hand joint range of motion between the two groups was compared (P>0.05), and the results were not statistically significant. But after 60 days and 90 days of treatment, the two groups showed significant differences. The statistical results showed P<0.05, which was statistically significant. It shows that there is no significant difference in the range of motion of the hand joints in the early treatment, but significant differences can be seen after 2-3 months of treatment. VR treatment can effectively increase the range of motion after burns. The treatment effect is shown in Figure 7.Table 5
Comparison of wound pruritus and wound pain in the control group and the VR treatment group on the 7, 14, and 28 days after treatment.
Observation itemTime (days)Control group (points)Exercise therapy group (points)PItching73.16 ± 0.782.54 ± 0.750.027142.18 ± 0.661.87 ± 0.700.003282.11 ± 0.721.61 ± 0.12< 0.001Pain76.55 ± 1.584.20 ± 1.51< 0.001143.88 ± 1.221.20 ± 1.02< 0.001282.25 ± 1.061.11 ± 0.77< 0.001Epilepsy306.27 ± 2.073.85 ± 1.53< 0.001606.45 ± 1.993.78 ± 1.74< 0.001906.45 ± 2.173.76 ± 1.6< 0.001Hand joint mobility302.75 ± 0.813.02 ± 0.990.001602.43 ± 0.792.92 ± 0.670.001Figure 7
Treatment effect.In order to find the best brain wave feature that can represent the fear of heights, we compared the best classification of 4 different features. The accuracy of different features in different brain wave frequency bands is shown in Table6. From Table 6, we can know that the devolatility analysis can achieve the best accuracy rate of 86.87% in the entire frequency band, and the correlation between high-frequency waves (alpha, beta, and gamma) and emotions is higher than that of low-frequency waves (delta and theta). In addition, the results of randomly selected 20 groups of experimenters before and after the depression grade ratio are shown in Figure 8. It can be seen from Figure 8 that there are two groups of experimenters that have not changed much before and after treatment, and the other 18 groups have obvious changes before and after treatment. Therefore, in general, we believe that VR has a certain effect on treating depression after burns.Table 6
Accuracy of different features in different brainwave frequency bands.
FeatureBrain waves (%)DeltaThetaAlphaBetaGammaAllDevolatility59.5766.1368.3980.2381.9786 87Hurst index43.1945.4653.1062.7466.7975.06Squared difference61.7664.6967.7869.7670.7980.09Approximate entropy72.8973.6875.3874.1273.8 282.65Figure 8
Comparison of experimenters before and after depression.
(a)(b)


## 5. Conclusion

VR technology is highly interactive, allowing patients to immerse themselves in VR scenes for effective intervention. The framework designed in this chapter is suitable for the patient’s EEG signal data obtained by the universal three-lead EEG collector. First, the EEG data is sent to the data processing module through a wireless protocol; then, the data processing module denoises the EEG data and performs feature extraction and feedback parameter calculation; after that, these parameters will be sent to the VR interaction engine; based on this, these parameters change the VR scene to capture and reflect the physiological activities of the patient’s brain in real time; finally, the patient uses the VR scene content presented by the real-time feedback of the captured EEG signal as a guide to making self-adjustment in time, and the electrical signal of captured brain at this time is again transmitted to the next work cycle and continues to feed back and present new VR interactive scenes to guide and intervene in the patient’s self-regulation behavior.Data processing: The incoming EEG data need to be denoised. First, we use a band-pass wave filter to eliminate the environmental noise generated by the power line or bypass electronic equipment in the EEG data. At the same time, since the electrodeposition of our EEG collector is located in the prefrontal lobe, the collected EEG data also need to adopt discrete wavelet transform and an improved adaptive noise elimination algorithm to eliminate ocular signal pollution. Subsequently, we divided dozens of features including relative power, absolute power, center frequency, relative center frequency asymmetry, absolute center frequency asymmetry, relative power asymmetry, and absolute power asymmetry of the four most commonly used extracted from brain wave. Finally, the feedback parameters calculated from these features will be transmitted to the VR interactive scene.VR interactive scene: It includes two independent input parameters. One includes basic information parameters such as the patient’s gender, age, and medical background. The other is responsible for outputting the calculated feedback parameters. The VR interactive scene combines the two parts of parameters in real time to select and generate the VR interactive scene. The patient feels the VR scene and interacts with the scene content in real time by wearing a VR helmet, adjusts the state by means of deep breathing, scene imagination, and other methods, and regulates the brain activity in an active way to improve the mental state. This research is a practical summary and theoretical innovation at the intersection of VR technology and psychology.



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*Source: 5531176-2021-03-24.xml*