# Prevalence and Risk Factors of Hypertension, Diabetes, and Dyslipidemia among Adults in Northwest China

Authors: Lin Qiu; Weihua Wang; Rina Sa; Feng Liu
Journal: International Journal of Hypertension
 (2021)

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## Abstract

Objective. To understand the prevalence and its risk factors of hypertension, diabetes mellitus, and dyslipidemia among adults aged over 18 years in Northwest China and provide data for the prevention and control of chronic diseases in Northwest China. Methods. Three waves of survey on chronic diseases and nutrition monitoring with multistage stratified cluster random sampling were conducted in 10 counties of Northwest China in 2013, 2015, and 2018, respectively. Personal information, socioeconomic status (SES), and behavioral risk factors (cigarettes smoking, alcohol consumption, diets, and physical activity) were collected by face-to-face interview. Height, weight, and blood pressure were measured, and blood glucose and serum lipid were tested. Prevalence of hypertension, diabetes, and dyslipidemia of the three waves was estimated, and multivariate logistic regression was used to analyze their risk factors. Results. The prevalence of hypertension, diabetes, and dyslipidemia was 41.59%, 11.16%, and 32.48%, respectively. Their standardized prevalence was 29.31%, 7.94%, and 31.54%. Univariate analysis showed that the prevalence of hypertension, diabetes, and dyslipidemia was significantly different among educational levels, marital status, occupation, smoking, drinking, central obesity, and BMI classification (P<0.05). Multivariate logistic regression analysis showed that factors like male gender, central obesity, overweight, and obesity were associated with hypertension, diabetes, and dyslipidemia (P<0.05). High BMI index is one of the risk factors of the three diseases. The odds ratio (OR) of general overweight associated with hypertension, diabetes, and dyslipidemia was 1.663, 1.206, and 1.579 compared to normal body weight, respectively. And that was 3.094, 1.565, and 2.285 for obesity. Age was one of the risk factors for hypertension and diabetes (P<0.05). Age groups of 45–59 years and 60 years and above were more associated with hypertension than of 18–44 age group (OR45-59 group = 2.777, OR60 years and above = 6.948), similar to their association with diabetes (OR45-59 group = 2.357, OR60 years and above = 3.521). Daily smoking is associated with diabetes and dyslipidemia (OR for diabetes = 1.217, OR for dyslipidemia = 1.287) and alcohol drinking associated with hypertension and dyslipidemia (OR for hypertension = 1.014, OR fordyslipidemia = 1.034). Hypertension, diabetes, and dyslipidemia were also associated with each other (P<0.05). The number of participants with hypertension, diabetes, and dyslipidemia accounted for 2.33% of all the participants, 15.60% for participants with hypertension and dyslipidemia, 4.58% for hypertension and diabetes, and 3.57% for diabetes and dyslipidemia, respectively. Conclusion. Factors like male, smoking, drinking, central obesity, overweight, and obesity were associated with hypertension, diabetes, and dyslipidemia in northwest China. Interventions on these risk factors and coexistence of the three diseases may help improve public health in this area.


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## Body

## 1. Introduction

The living standards of Chinese people have been greatly improved with the rise economy, and their lifestyle and diet patterns have also changed. Noncommunicable chronic diseases, such as cardiovascular and cerebrovascular diseases, have become the main threat to public health of China [1]. Some prospective studies and clinical trials have suggested that hypertension, diabetes, and dyslipidemia are major risk factors for cardiovascular and cerebrovascular diseases [2]. Northwest China is dry and cold, especially in winter, and its economy is less developed. Health literacy of local residents was relatively weak. All resulted in cardiovascular and cerebrovascular diseases becoming the main health treat [3]. This study aimed to have a clue on the prevalence of hypertension, diabetes, and dyslipidemia among population over 18 years old in Northwest China with three cross-sectional surveys from 2013 to 2018. We also investigated the possible risk factors of hypertension, diabetes, and dyslipidemia to provide information on prevention and control chronic diseases locally.


## 2. Methods

### 2.1. Study Population

According to thework plan for monitoring chronic diseases and nutrition of Chinese residents, we carried out survey of chronic diseases and nutrition monitoring among adult in 2013, 2015, and 2018, in 10 counties and districts (Lianhu, Meixian, Chencang, Jingyang, Huayin, Huangling, Baota, Lueyang, Xunyang, and Shangzhou) in northwest China. The respondents were residents aged 18 or older who had lived in the monitored area for 6 months or more during the 12 months prior to the survey. Before the investigation, the subjects in the sampled area should be thoroughly investigated, and then the subjects were recruited by means of community/village committee broadcast publicity and village doctors’ mobilization, etc. The investigation should be carried out in a centralized way.


### 2.2. Sample Size Calculation

The three waves of survey were cross-sectional. The sample size of each was calculated by stratified method. China divided into 31 layers based on its provincial level, multiplied by layers of urban and rural area, equaled to a total of 62 layers. The sample size is calculated as follows:(1)N=deffu2p1−pd2,where u = 1.96, р is the prevalence of diabetes from the last year (9.7% in 2013 and 2015, and 10.4% in 2018), design efficacy (deff) is 3, the relative error (r) = 20%, and d = 20% × the prevalence of diabetes. According to the value of parameter and considering 10% of no-response rate, a total of 302 counties in China were selected to be the sample site, and 10 counties in Shaanxi Province in Northwest China were selected. In total, 18501 participants were enrolled in the three waves.


### 2.3. Sampling

We used a multistage cluster random sampling method in the three surveys. In the first stage, 3 townships/streets were randomly selected from each county. In the second stage, two villages were randomly selected from each selected township/street. In the third stage, one group of villager/resident was randomly selected from each selected village. In the fourth stage, 45 households were selected from each selected villagers residents group. All the residents aged 18 or above in the selected households were invited to the survey.


### 2.4. Measurements and Definition

#### 2.4.1. Study Variables and Measures

Face-to-face interview with questionnaires, physical examination, and laboratory test were adopted in the three surveys and carried out by investigators who had received unified training and passed the examination. Three parts were included in the survey as follows: socioeconomic status (residency, age, gender, nationality, education level, marital status, occupation, and family annual income), behavioral risk factors (smoking, drinking, diet, and physical activity), and biological risk factors (waist circumference, weight, height, blood pressure, blood glucose, and blood lipid). The electronic sphygmomanometer and measurement method were used to obtain the blood pressure data of the subjects. The Omron HBP-1300 electronic sphygmomanometer was used for blood pressure measurement. The blood pressure was measured for 3 times in a quiet environment (each interval was 1 min), and the mean value of the next 2 times was taken as the individual blood pressure value, accurate to 1 mm Hg. 10 ml of fasting venous blood was collected to detect fasting blood glucose, total cholesterol, triglyceride, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol; 75 g of anhydrous glucose was given orally to the subjects without diabetes history, and 2 ml of venous blood was collected 2 hours after taking glucose . Plasma blood glucose was determined by the hexokinase method or glucose oxidase method; total cholesterol was determined by the cholesterol oxidase amino-antipyrlophenol method (CHOD-PAP), triglyceride was determined by the glycerin phosphate oxidase 4-chloric acid method, and high-density lipoprotein cholesterol and low-density lipoprotein cholesterol were determined by the homogeneous enzyme colorimetry.


#### 2.4.2. Exposure and Outcome

Insufficient consumption of vegetables and fruits was defined as average daily intake <400 g. Excessive intake of red meat was defined as average daily intake >100 g. The average daily salt intake >6 g was defined as excessive salt intake [4]. Central obesity referred to male waist circumference ≥85 cm or female waist circumference ≥80 cm. BMI <18.5 kg/m2 is low body weight, 18.5 kg/m2 ≤ BMI < 24.0 kg/m2 is normal weight, 24.0 kg/m2 ≤ BMI < 28.0 kg/m2 is overweight, and BMI ≥ 28.0 kg/m2 is obesity [5]. Hypertensive patients: according to the Chinese guidelines for prevention and treatment of hypertension (revised version in 2018) [6], hypertension is defined as SBP ≥ 140 mm Hg and/or DBP ≥90 mm Hg or those who had been diagnosed with hypertension in hospitals and took antihypertensive drugs in recent 2 weeks [6]. Diabetics were those with fasting blood glucose (FBG) ≥7.0 mmol/L and/or 2-hour oral glucose tolerance test blood glucose (OGTT) ≥11.1 mmol/l or those who have been diagnosed with diabetes by hospitals [7]. Total cholesterol ≥6.22 mmol/L is hypercholesterolemia; HDL-C < 1.04 mmol/L is low-density lipoprotein cholesterol; low-density lipoprotein cholesterol ≥4.14 mmol/L is high-density lipoprotein cholesterol; and triglyceride ≥2.26 mmol/L is hypertriglyceridemia. Those who meet any of the above are defined as dyslipidemia [8].


### 2.5. Statistical Analysis

The continuous data were described byχ¯ ± s. The categorized data were described by frequency and proportion and compared by the χ2 test. Age-standardized prevalence of hypertension, diabetes, and dyslipidemia in the study was calculated using the 6th National Census of China in 2010. The multivariate logistic regression model was used to examine the association of hypertension, diabetes, dyslipidemia, and the related risk factors. Model I was constructed to explore their association. If р value < 0.20, the risk factors were involved in the model II to determine their associations. We set α = 0.05 to judge the statistical significance. SPSS 25.0 software was used for statistical analysis in the study. Variables and their values are shown in Table 1. The logistic regression model is as follows:(2)LogitP=lnβ0+β1X0+⋯+βmXm.Table 1
Values of variables in multivariate logistic regression model.
VariablesValuesSex0 = female; 1 = maleResidency0 = urban areas; 1 = rural areasAge (year)0 = 18–44 years old; 1 = 45–59 years old; 2 = 60 years old or aboveEthnicity0 = others; 1 = HanEducation level0 = primary school or below; 1 = middle school; 2 = college or aboveMarital status0 = separated/divorced/widowed; 1 = single; 2 = married or cohabitOccupation0 = others; 1 = farmersFamily income (RMB)0 = <5000; 1 = 5000–9999; 2 = 10000–19999; 3 =≥20000Cigarette smoking0 = never; 1 = daily smoking; 2 = non-daily smoking; 3 = ex-smokingAlcohol drinking0 = never; 1 = drinking in the past 12 month; 2 = drinking in the past 1 monthDaily consumption of vegetables and fruits (g)0 = <400, 1 = >400Daily salt intake (g)0 = <6, 1 =>6Daily red meat intake (g)0 = <100, 1=>100BMI groups0 = normal body weight; 1 = underweight; 2 = overweight; 3 = obesityCentral obesity0 = no; 1 = yesHypertension0 = no; 1 = yesDiabetes0 = no; 1 = yesDyslipidemia0 = no; 1 = yeswhereβ0 is a constant term or intercept and β1, β2,…,βm are for the logistic regression model of regression coefficient, according to the sample data to estimate the constant term and coefficient of regression of logistic regression model, and then we describe and analyze the relationship between the response variable and the independent variable and calculate the probability of the results under the characteristic conditions.


## 2.1. Study Population

According to thework plan for monitoring chronic diseases and nutrition of Chinese residents, we carried out survey of chronic diseases and nutrition monitoring among adult in 2013, 2015, and 2018, in 10 counties and districts (Lianhu, Meixian, Chencang, Jingyang, Huayin, Huangling, Baota, Lueyang, Xunyang, and Shangzhou) in northwest China. The respondents were residents aged 18 or older who had lived in the monitored area for 6 months or more during the 12 months prior to the survey. Before the investigation, the subjects in the sampled area should be thoroughly investigated, and then the subjects were recruited by means of community/village committee broadcast publicity and village doctors’ mobilization, etc. The investigation should be carried out in a centralized way.


## 2.2. Sample Size Calculation

The three waves of survey were cross-sectional. The sample size of each was calculated by stratified method. China divided into 31 layers based on its provincial level, multiplied by layers of urban and rural area, equaled to a total of 62 layers. The sample size is calculated as follows:(1)N=deffu2p1−pd2,where u = 1.96, р is the prevalence of diabetes from the last year (9.7% in 2013 and 2015, and 10.4% in 2018), design efficacy (deff) is 3, the relative error (r) = 20%, and d = 20% × the prevalence of diabetes. According to the value of parameter and considering 10% of no-response rate, a total of 302 counties in China were selected to be the sample site, and 10 counties in Shaanxi Province in Northwest China were selected. In total, 18501 participants were enrolled in the three waves.


## 2.3. Sampling

We used a multistage cluster random sampling method in the three surveys. In the first stage, 3 townships/streets were randomly selected from each county. In the second stage, two villages were randomly selected from each selected township/street. In the third stage, one group of villager/resident was randomly selected from each selected village. In the fourth stage, 45 households were selected from each selected villagers residents group. All the residents aged 18 or above in the selected households were invited to the survey.


## 2.4. Measurements and Definition

### 2.4.1. Study Variables and Measures

Face-to-face interview with questionnaires, physical examination, and laboratory test were adopted in the three surveys and carried out by investigators who had received unified training and passed the examination. Three parts were included in the survey as follows: socioeconomic status (residency, age, gender, nationality, education level, marital status, occupation, and family annual income), behavioral risk factors (smoking, drinking, diet, and physical activity), and biological risk factors (waist circumference, weight, height, blood pressure, blood glucose, and blood lipid). The electronic sphygmomanometer and measurement method were used to obtain the blood pressure data of the subjects. The Omron HBP-1300 electronic sphygmomanometer was used for blood pressure measurement. The blood pressure was measured for 3 times in a quiet environment (each interval was 1 min), and the mean value of the next 2 times was taken as the individual blood pressure value, accurate to 1 mm Hg. 10 ml of fasting venous blood was collected to detect fasting blood glucose, total cholesterol, triglyceride, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol; 75 g of anhydrous glucose was given orally to the subjects without diabetes history, and 2 ml of venous blood was collected 2 hours after taking glucose . Plasma blood glucose was determined by the hexokinase method or glucose oxidase method; total cholesterol was determined by the cholesterol oxidase amino-antipyrlophenol method (CHOD-PAP), triglyceride was determined by the glycerin phosphate oxidase 4-chloric acid method, and high-density lipoprotein cholesterol and low-density lipoprotein cholesterol were determined by the homogeneous enzyme colorimetry.


### 2.4.2. Exposure and Outcome

Insufficient consumption of vegetables and fruits was defined as average daily intake <400 g. Excessive intake of red meat was defined as average daily intake >100 g. The average daily salt intake >6 g was defined as excessive salt intake [4]. Central obesity referred to male waist circumference ≥85 cm or female waist circumference ≥80 cm. BMI <18.5 kg/m2 is low body weight, 18.5 kg/m2 ≤ BMI < 24.0 kg/m2 is normal weight, 24.0 kg/m2 ≤ BMI < 28.0 kg/m2 is overweight, and BMI ≥ 28.0 kg/m2 is obesity [5]. Hypertensive patients: according to the Chinese guidelines for prevention and treatment of hypertension (revised version in 2018) [6], hypertension is defined as SBP ≥ 140 mm Hg and/or DBP ≥90 mm Hg or those who had been diagnosed with hypertension in hospitals and took antihypertensive drugs in recent 2 weeks [6]. Diabetics were those with fasting blood glucose (FBG) ≥7.0 mmol/L and/or 2-hour oral glucose tolerance test blood glucose (OGTT) ≥11.1 mmol/l or those who have been diagnosed with diabetes by hospitals [7]. Total cholesterol ≥6.22 mmol/L is hypercholesterolemia; HDL-C < 1.04 mmol/L is low-density lipoprotein cholesterol; low-density lipoprotein cholesterol ≥4.14 mmol/L is high-density lipoprotein cholesterol; and triglyceride ≥2.26 mmol/L is hypertriglyceridemia. Those who meet any of the above are defined as dyslipidemia [8].


## 2.4.1. Study Variables and Measures

Face-to-face interview with questionnaires, physical examination, and laboratory test were adopted in the three surveys and carried out by investigators who had received unified training and passed the examination. Three parts were included in the survey as follows: socioeconomic status (residency, age, gender, nationality, education level, marital status, occupation, and family annual income), behavioral risk factors (smoking, drinking, diet, and physical activity), and biological risk factors (waist circumference, weight, height, blood pressure, blood glucose, and blood lipid). The electronic sphygmomanometer and measurement method were used to obtain the blood pressure data of the subjects. The Omron HBP-1300 electronic sphygmomanometer was used for blood pressure measurement. The blood pressure was measured for 3 times in a quiet environment (each interval was 1 min), and the mean value of the next 2 times was taken as the individual blood pressure value, accurate to 1 mm Hg. 10 ml of fasting venous blood was collected to detect fasting blood glucose, total cholesterol, triglyceride, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol; 75 g of anhydrous glucose was given orally to the subjects without diabetes history, and 2 ml of venous blood was collected 2 hours after taking glucose . Plasma blood glucose was determined by the hexokinase method or glucose oxidase method; total cholesterol was determined by the cholesterol oxidase amino-antipyrlophenol method (CHOD-PAP), triglyceride was determined by the glycerin phosphate oxidase 4-chloric acid method, and high-density lipoprotein cholesterol and low-density lipoprotein cholesterol were determined by the homogeneous enzyme colorimetry.


## 2.4.2. Exposure and Outcome

Insufficient consumption of vegetables and fruits was defined as average daily intake <400 g. Excessive intake of red meat was defined as average daily intake >100 g. The average daily salt intake >6 g was defined as excessive salt intake [4]. Central obesity referred to male waist circumference ≥85 cm or female waist circumference ≥80 cm. BMI <18.5 kg/m2 is low body weight, 18.5 kg/m2 ≤ BMI < 24.0 kg/m2 is normal weight, 24.0 kg/m2 ≤ BMI < 28.0 kg/m2 is overweight, and BMI ≥ 28.0 kg/m2 is obesity [5]. Hypertensive patients: according to the Chinese guidelines for prevention and treatment of hypertension (revised version in 2018) [6], hypertension is defined as SBP ≥ 140 mm Hg and/or DBP ≥90 mm Hg or those who had been diagnosed with hypertension in hospitals and took antihypertensive drugs in recent 2 weeks [6]. Diabetics were those with fasting blood glucose (FBG) ≥7.0 mmol/L and/or 2-hour oral glucose tolerance test blood glucose (OGTT) ≥11.1 mmol/l or those who have been diagnosed with diabetes by hospitals [7]. Total cholesterol ≥6.22 mmol/L is hypercholesterolemia; HDL-C < 1.04 mmol/L is low-density lipoprotein cholesterol; low-density lipoprotein cholesterol ≥4.14 mmol/L is high-density lipoprotein cholesterol; and triglyceride ≥2.26 mmol/L is hypertriglyceridemia. Those who meet any of the above are defined as dyslipidemia [8].


## 2.5. Statistical Analysis

The continuous data were described byχ¯ ± s. The categorized data were described by frequency and proportion and compared by the χ2 test. Age-standardized prevalence of hypertension, diabetes, and dyslipidemia in the study was calculated using the 6th National Census of China in 2010. The multivariate logistic regression model was used to examine the association of hypertension, diabetes, dyslipidemia, and the related risk factors. Model I was constructed to explore their association. If р value < 0.20, the risk factors were involved in the model II to determine their associations. We set α = 0.05 to judge the statistical significance. SPSS 25.0 software was used for statistical analysis in the study. Variables and their values are shown in Table 1. The logistic regression model is as follows:(2)LogitP=lnβ0+β1X0+⋯+βmXm.Table 1
Values of variables in multivariate logistic regression model.
VariablesValuesSex0 = female; 1 = maleResidency0 = urban areas; 1 = rural areasAge (year)0 = 18–44 years old; 1 = 45–59 years old; 2 = 60 years old or aboveEthnicity0 = others; 1 = HanEducation level0 = primary school or below; 1 = middle school; 2 = college or aboveMarital status0 = separated/divorced/widowed; 1 = single; 2 = married or cohabitOccupation0 = others; 1 = farmersFamily income (RMB)0 = <5000; 1 = 5000–9999; 2 = 10000–19999; 3 =≥20000Cigarette smoking0 = never; 1 = daily smoking; 2 = non-daily smoking; 3 = ex-smokingAlcohol drinking0 = never; 1 = drinking in the past 12 month; 2 = drinking in the past 1 monthDaily consumption of vegetables and fruits (g)0 = <400, 1 = >400Daily salt intake (g)0 = <6, 1 =>6Daily red meat intake (g)0 = <100, 1=>100BMI groups0 = normal body weight; 1 = underweight; 2 = overweight; 3 = obesityCentral obesity0 = no; 1 = yesHypertension0 = no; 1 = yesDiabetes0 = no; 1 = yesDyslipidemia0 = no; 1 = yeswhereβ0 is a constant term or intercept and β1, β2,…,βm are for the logistic regression model of regression coefficient, according to the sample data to estimate the constant term and coefficient of regression of logistic regression model, and then we describe and analyze the relationship between the response variable and the independent variable and calculate the probability of the results under the characteristic conditions.


## 3. Results

### 3.1. Characteristics of the Participants

The total population of the 10 counties is 4023603. A total of 18501 participants at 18 years old or above in northwest China were investigated in the survey from 2013 to 2018. The average age was (51.51 ± 14.01) years old. Among all the participants, 8610 (46.54%) were males and 9891 (53.46%) were females. 7337 (39.66%) were from urban areas, and 11164 (60.34%) were from rural areas. The number, (prevalence and age-standardized prevalence) of hypertension, diabetes, and dyslipidemia patients was 7656 (41.59%, 29.31%), 1340 (11.16%, 7.94%), and 5887 (32.48%, 31.54%), respectively. The prevalence of hypertension, diabetes, and dyslipidemia was significantly different in the education level, marital status, occupation, smoking, drinking, central obesity, and BMI groups (P<0.05). Table 2.Table 2
Baseline of the participants in northwest China.
VariablesHypertensionDiabetesDyslipidemiaYesNoPYesNoPYesNoPOverall7656 (41.59)10752 (58.41)1340 (11.16)10668 (88.84)5887 (32.48)12239 (67.52)ResidencyUrban3066 (40.05)4252 (39.55)0.494650 (48.51)4097 (38.4)＜0.0012455 (41.7)4756 (38.86)＜0.001Rural4590 (59.95)6500 (60.45)690 (51.49)6571 (61.6)3432 (58.30)7483 (61.14)SexFemale4131 (53.96)5718 (53.18)0.298688 (51.34)5872 (55.04)0.0102780 (47.22)6932 (56.64)＜0.001Male3525 (46.04)5034 (46.82)652 (48.66)4796 (44.96)3107 (52.78)5307 (43.36)EthnicityOthers57 (0.74)105 (0.98)0.09722 (1.64)120 (1.13)0.09951 (0.87)108 (0.88)0.915Han7595 (99.26)10641 (99.02)1317 (98.36)10539 (98.87)5833 (99.13)12128 (99.12)Education levelPrimary school or below4081 (53.35)4052 (37.72)＜0.001617 (46.08)4515 (42.38)0.0312392 (40.66)5613 (45.89)＜0.001Middle school3303 (43.18)5805 (54.04)629 (46.98)5394 (50.63)3086 (52.46)5892 (48.17)College or above266 (3.48)886 (8.25)93 (6.95)745 (6.99)405 (6.88)727 (5.94)Marital statusSeparated/divorced/widowed714 (9.33)498 (4.64)＜0.001131 (9.78)775 (7.27)＜0.001355 (6.03)833 (6.81)＜0.001Single147 (1.92)711 (6.62)26 (1.94)559 (5.25)265 (4.5)576 (4.71)Married or cohabit6791 (88.75)9535 (88.75)1182 (88.27)9323 (87.48)5264 (89.46)10825 (88.48)OccupationOthers3384 (44.23)5249 (48.85)＜0.001749 (55.94)5281 (49.55)＜0.0012878 (48.92)5621 (45.94)＜0.001Farmer4267 (55.77)5496 (51.15)590 (44.06)5376 (50.45)3005 (51.08)6614 (54.06)Age (year)57.92 ± 11.7947.02 ± 13.6658.18 ± 12.0050.68 ± 14.1651.81 ± 13.7851.45 ± 14.0518–441020 (13.32)4652 (43.27)＜0.001175 (13.06)3589 (33.64)＜0.0011773 (30.12)3797 (31.02)0.46445–593137 (40.97)4195 (39.02)550 (41.04)4182 (39.2)2369 (40.24)4864 (39.74)≥603499 (45.70)1905 (17.72)615 (45.9)2897 (27.16)1745 (29.64)3578 (29.23)Family income (RMB)<5000358 (8.83)290 (5.66)＜0.00130 (6.32)247 (6.38)0.725204 (6.74)437 (7.31)0.7165000–9999383 (9.45)370 (7.22)39 (8.21)263 (6.79)244 (8.06)490 (8.19)10000–19999726 (17.91)801 (15.63)68 (14.32)566 (14.62)516 (17.05)985 (16.47)≥200002586 (63.80)3664 (71.49)338 (71.16)2796 (72.21)2062 (68.14)4069 (68.03)Cigarette smokingNever2753 (25.61)1761 (23.00)＜0.0012597 (24.35)273 (20.37)＜0.0012769 (22.62)1664 (28.27)＜0.001Daily smoking247 (2.30)202 (2.64)247 (2.32)32 (2.39)291 (2.38)149 (2.53)Non-daily smoking451 (4.20)518 (6.77)479 (4.49)120 (8.96)595 (4.86)362 (6.15)Ex-smoking7297 (67.89)5175 (67.59)7341 (68.84)915 (68.28)8584 (70.14)3712 (63.05)Alcohol drinkingNever1805 (16.80)1197 (15.63)＜0.0011492 (13.99)166 (12.39)0.0281914 (15.64)1045 (17.75)＜0.001Drinking in the past 12 months1516 (14.11)753 (9.84)1512 (14.18)165 (12.31)1412 (11.54)826 (14.03)Drinking in the past 1 month7425 (69.10)5706 (74.53)7659 (71.83)1009 (75.30)8912 (72.82)4016 (68.22)Central obesityNo2701 (35.47)5777 (54.77)＜0.001362 (27.28)5047 (47.61)＜0.0011800 (30.72)6610 (54.34)＜0.001Yes4913 (64.53)4771 (45.23)965 (72.72)5554 (52.39)4060 (69.28)5554 (45.66)BMI groupsNormal body weight2858 (37.52)5750 (54.52)＜0.001440 (33.16)5227 (49.31)＜0.0011932 (32.97)6613 (54.36)＜0.001Underweight138 (1.81)402 (3.81)23 (1.73)334 (3.15)59 (1.01)475 (3.9)Overweight3084 (40.49)3450 (32.71)567 (42.73)3735 (35.23)2584 (44.1)3900 (32.06)Obesity1537 (20.18)945 (8.96)297 (22.38)1305 (12.31)1285 (21.93)1178 (9.68)Daily salt intake (g)<62809 (38.46)4195 (41.28)＜0.001548 (44.05)4229 (43.05)0.5032363 (42.36)4518 (38.88)＜0.001>64495 (61.54)5967 (58.72)696 (55.95)5594 (56.95)3215 (57.64)7101 (61.12)Daily consumption of vegetable and fruit (g)>4002972 (39.54)5101 (47.99)＜0.001705 (52.61)5710 (53.54)0.5192652 (45.65)5307 (44)0.038<4004545 (60.46)5528 (52.01)635 (47.39)4954 (46.46)3158 (54.35)6755 (56)Daily red meat intake (g)<1005846 (94.92)8429 (93.20)＜0.0011240 (92.54)9936 (93.17)0.3874490 (92.75)9589 (94.38)＜0.001>100313 (5.08)615 (6.80)100 (7.46)728 (6.83)351 (7.25)571 (5.62)


### 3.2. Cluster Analysis of Hypertension, Diabetes, and Dyslipidemia

The results showed that the number of people with three diseases accounted for 2.33%, and the number of people with hypertension and diabetes, hypertension and dyslipidemia, and diabetes and dyslipidemia accounted for 4.58%, 15.60%, and 3.57%, respectively (Figure1).Figure 1
The overlap of hypertension, diabetes, and dyslipidemia in Northwest China.Note. A is hypertension, B is diabetes, and C is dyslipidemia. The percentages shown in each part of the figure are the proportion of the diseases in the population.


### 3.3. Risk Factor Analysis

#### 3.3.1. Risk Factors of Hypertension

The results in model I showed that there were no association between family average annual income, smoking, daily average red meat intake, and hypertension (P>0.200). The rest of the risk factors in Table 1 are included in model II, the results showed that gender, age, alcohol consumption, central obesity, overweight and obesity, insufficient daily intake of vegetables and fruits, diabetes, and dyslipidemia were associated with hypertension. Those who were 45–59 years old and 60 years old and above were 2.78 times (95% CI 2.475–3.116) and 6.948 times (95% CI 6.107–7.905) prone to have hypertension than those at 18–44 years old, respectively. Overweight and obesity were 1.66 times (95% CI 1.489–1.858) and 3.094 times (95% CI) to have hypertension than those with normal weight, respectively. Participants with diabetes were 1.82 times (95% CI 1.586–2.085) to have hypertension than those without. And that was 1.247 times (95% CI 1.133–1.371) in participants with dyslipidemia. Participants in rural areas, graduated from middle school, junior college or above, unmarried or married and cohabitation, and low weight were less likely to having hypertension (Table 3).Table 3
Logistic regression analysis on risk factors of hypertension among adults from northwest China.
VariablesModel IModel IIOR (95% CI)POR (95% CI)PResidencyRural0.836 (0.716–0.975)0.0230.906 (0.826–0.995)0.039SexMale1.260 (1.033–1.536)0.0231.106 (1.003–1.219)0.042EthnicityHan1.628 (0.917–2.890)0.0961.294 (0.843–1.985)0.238Education levelMiddle school0.823 (0.712–0.952)0.0090.801 (0.729–0.880)＜0.001College or above0.560 (0.393–0.799)0.0010.574 (0.461–0.714)＜0.001Marital statusSingle0.546 (0.322–0.924)0.0240.557 (0.409–0.758)＜0.001Married or cohabit0.709 (0.536–0.938)0.0160.811 (0.690–0.954)0.011OccupationFarmer1.090 (0.941–1.264)0.251Age (year)45–592.582 (2.141–3.113)＜0.0012.777 (2.475–3.116)＜0.001≥606.158 (5.013–7.565)＜0.0016.948 (6.107–7.905)＜0.001Family income (RMB)5000–99991.000 (0.696–1.435)0.99910000–199991.186 (0.863–1.630)0.292≥200001.080 (0.815–1.431)0.591Cigarette smokingDaily smoking0.944 (0.759–1.175)0.606Non-daily smoking1.269 (0.790–2.037)0.325Ex-smoking0.973 (0.702–1.349)0.871Alcohol drinkingDrinking in the past 12 months0.752 (0.587–0.963)0.3470.780 (0.678–0.896)0.833Drinking in the past 1 month0.912 (0.752–1.105)0.0241.014 (0.889–1.158)＜0.001Central obesityYes1.384 (1.168–1.639)＜0.0011.383 (1.239–1.544)＜0.001BMI groupsUnderweight0.532 (0.322–0.876)0.0130.559 (0.414–0.753)＜0.001Overweight1.597 (1.348–1.892)＜0.0011.663 (1.489–1.858)＜0.001Obesity2.805 (2.207–3.566)＜0.0013.094 (2.653–3.609)＜0.001Daily salt intake (g)>61.161 (1.007–1.338)0.0401.050 (0.961–1.148)0.282Daily consumption of vegetables and fruits (g)<4001.152 (1.005–1.322)0.0431.273 (1.167–1.389)＜0.001Daily red meat intake (g)>1000.954 (0.664–1.371)0.800DiabetesYes2.207 (1.754–2.777)＜0.0011.818 (1.586–2.085)＜0.001DyslipidemiaYes1.227 (1.057–1.423)0.0071.247 (1.133–1.371)＜0.001Note. In model I, hypertension is taken as dependent variable; residency, age, sex, ethnicity, education level, marital status, occupation, family income, smoking, drinking, central obesity, BMI groups, salt intake, vegetable and fruit consumption, red meat intake, diabetes, and dyslipidemia are taken as independent variables. In model II, we further excluded family average annual income, smoking, and daily red meat intake, as their P>0.20 in model I.


#### 3.3.2. Risk Factors of Diabetes

The results in model II showed that gender, age, daily smoking, central obesity, overweight and obesity, hypertension, and dyslipidemia were associated with diabetes. Those who were 45–59 years old and 60 years old and above were 2.357 times (95% CI 1.952–2.847) and 3.521 times (95% CI 2.894–4.285) prone to have risk of diabetes than those who were 18–44 years old, respectively. Those who were overweight and obesity were 1.206 times (95% CI 1.028–1.415) and 1.565 times (95% CI 1.284–1.907) to have the risk of diabetes than those with normal weight, respectively. Participants with hypertension or dyslipidemia were 1.761 times (95% CI 1.546–2.006) and 1.934 times (95% CI 1.708–2.189) to get diabetes than those without them, respectively. Farmers and those who were living in rural areas were less likely to get diabetes (Table4).Table 4
Logistic regression analysis on risk factors of diabetes among adults from northwest China.
VariablesModel IModel IIOR (95% CI)POR (95% CI)PResidencyRural0.743 (0.589–0.938)0.0120.706 (0.621–0.803)＜0.001SexMale1.256 (0.939–1.679)0.1241.351 (1.148–1.588)＜0.001EthnicityHan0.927 (0.457–1.881)0.833Education levelMiddle school1.006 (0.804–1.260)0.955College or above1.355 (0.817–2.248)0.239Marital statusSingle0.488 (0.180–1.325)0.1590.685 (0.430–1.090)0.110Married or cohabit0.893 (0.617–1.293)0.5490.950 (0.770–1.171)0.628OccupationFarmer0.740 (0.591–0.926)0.0090.783 (0.689–0.891)＜0.001Age (year)45–592.723 (1.886–3.931)＜0.0012.357 (1.952–2.847)＜0.001≥604.075 (2.794–5.942)＜0.0013.521 (2.894–4.285)＜0.001Family income (RMB)5000–99991.310 (0.766–2.242)0.32410000–199991.099 (0.676–1.786)0.703≥200001.107 (0.719–1.704)0.644Cigarette smokingDaily smoking1.104 (0.720–1.694)0.0831.217 (0.946–1.566)＜0.001Non-daily smoking0.940 (0.467–1.890)0.8620.895 (0.594–1.347)0.594Ex-smoking0.749 (0.540–1.039)0.6490.715 (0.592–0.864)0.126Alcohol drinkingDrinking in the past 12 months0.938 (0.699–1.260)0.672Drinking in the past 1 month1.013 (0.700–1.464)0.947Central obesityYes1.627 (1.226–2.159)0.0011.456 (1.234–1.717)＜0.001BMI groups underweight0.919 (0.360–2.350)0.8601.151 (0.736–1.800)0.538Overweight1.153 (0.884–1.504)0.2931.206 (1.028–1.415)0.022Obesity1.411 (1.016–1.958)0.0401.565 (1.284–1.907)＜0.001Daily salt intake (g)>60.924 (0.744–1.147)0.475Daily consumption of vegetable and fruit (g)<4000.968 (0.786–1.193)0.763Daily red meat intake (g)>1001.262 (0.744–2.138)0.388HypertensionYes2.206 (1.753–2.777)＜0.0011.761 (1.546–2.006)＜0.001DyslipidemiaYes2.010 (1.630–2.478)＜0.0011.934 (1.708–2.189)＜0.001Note. In model I, hypertension is taken as dependent variable; residency, age, sex, ethnicity, education level, marital status, occupation, family income, smoking, drinking, central obesity, BMI groups, salt intake, vegetable and fruit consumption, red meat intake, diabetes, and dyslipidemia are taken as independent variables. In model II, we further excluded ethnicity, education level, family income, drinking, salt intake, daily red meat intake, and red meat intake, as their P>0.20 in model I.


#### 3.3.3. Risk Factors of Dyslipidemia

The results in model II showed that gender, education level, daily smoking, drinking, central obesity, overweight and obesity, hypertension, and diabetes were associated with dyslipidemia. Overweight and obesity were 1.579 times (95% CI 1.420–1.755) and 2.285 times (95% CI 1.986–2.628) prone to have the risk of dyslipidemia than those with normal weight, respectively. Those with hypertension were 1.242 times (95% CI 1.134–1.360) prone to have the risk of dyslipidemia than those without it. And that was 1.924 times (95% CI 1.699–2.179) for participants with diabetes. Low body weight was less likely to get dyslipidemia (Table5).Table 5
Logistic regression analysis on risk factors of dyslipidemia among adults from northwest China.
VariablesModel IModel IIOR (95% CI)POR (95% CI)PResidencyRural0.927 (0.792–1.085)0.343SexMale1.245 (1.018–1.522)0.0331.401 (1.245–1.576)＜0.001EthnicityHan0.621 (0.365–1.057)0.0791.031 (0.709–1.500)0.872Education levelMiddle school1.166 (1.004–1.354)0.0441.174 (1.072–1.286)0.001College or above1.096 (0.790–1.522)0.5831.377 (1.155–1.642)＜0.001Marital statusSingle1.078 (0.658–1.766)0.766Married or cohabit1.047 (0.786–1.395)0.753OccupationFarmer1.022 (0.878–1.189)0.777Age (year)45–590.814 (0.677–0.977)0.0270.910 (0.820–1.009)0.075≥600.799 (0.650–0.983)0.0340.917 (0.813–1.036)0.164Family income (RMB)5000–99990.874 (0.596–1.283)0.49310000–199991.061 (0.762–1.478)0.726≥200001.065 (0.793–1.430)0.677Cigarette smokingDaily smoking1.309 (1.048–1.635)0.0181.287 (1.130–1.467)＜0.001Non-daily smoking0.873 (0.533–1.430)0.5900.907 (0.680–1.209)0.505Ex-smoking1.169 (0.842–1.624)0.3500.988 (0.805–1.212)0.906Alcohol drinkingDrinking in the past 12 months0.855 (0.665–1.099)0.0071.034 (0.910–1.175)0.041Drinking in the past 1 month0.764 (0.628–0.929)0.2220.874 (0.769–0.994)0.611Central obesityYes1.683 (1.410–2.010)＜0.0011.952 (1.754–2.172)＜0.001BMI groups underweight0.347 (0.159–0.760)0.0080.565 (0.403–0.793)0.001Overweight1.778 (1.497–2.113)＜0.0011.579 (1.420–1.755)＜0.001Obesity2.940 (2.339–3.696)＜0.0012.285 (1.986–2.628)＜0.001Daily salt intake (g)>61.018 (0.880–1.177)0.812Daily consumption of vegetable and fruit (g)<4001.054 (0.917–1.213)0.459Daily red meat intake (g)>1000.698 (0.482–1.011)0.0571.097 (0.935–1.287)0.257HypertensionYes1.210 (1.042–1.404)0.0121.242 (1.134–1.360)＜0.001DiabetesYes1.997 (1.619–2.462)＜0.0011.924 (1.699–2.179)＜0.001Note. In model I, hypertension is taken as dependent variable; residency, age, sex, ethnicity, education level, marital status, occupation, family income, smoking, drinking, central obesity, BMI groups, salt intake, vegetable and fruit consumption, red meat intake, diabetes, and dyslipidemia are taken as independent variables. In model II, we further excluded residency, marital status, occupation, family income, salt intake, daily red meat intake, and red meat intake, as their P>0.20 in model I.


## 3.1. Characteristics of the Participants

The total population of the 10 counties is 4023603. A total of 18501 participants at 18 years old or above in northwest China were investigated in the survey from 2013 to 2018. The average age was (51.51 ± 14.01) years old. Among all the participants, 8610 (46.54%) were males and 9891 (53.46%) were females. 7337 (39.66%) were from urban areas, and 11164 (60.34%) were from rural areas. The number, (prevalence and age-standardized prevalence) of hypertension, diabetes, and dyslipidemia patients was 7656 (41.59%, 29.31%), 1340 (11.16%, 7.94%), and 5887 (32.48%, 31.54%), respectively. The prevalence of hypertension, diabetes, and dyslipidemia was significantly different in the education level, marital status, occupation, smoking, drinking, central obesity, and BMI groups (P<0.05). Table 2.Table 2
Baseline of the participants in northwest China.
VariablesHypertensionDiabetesDyslipidemiaYesNoPYesNoPYesNoPOverall7656 (41.59)10752 (58.41)1340 (11.16)10668 (88.84)5887 (32.48)12239 (67.52)ResidencyUrban3066 (40.05)4252 (39.55)0.494650 (48.51)4097 (38.4)＜0.0012455 (41.7)4756 (38.86)＜0.001Rural4590 (59.95)6500 (60.45)690 (51.49)6571 (61.6)3432 (58.30)7483 (61.14)SexFemale4131 (53.96)5718 (53.18)0.298688 (51.34)5872 (55.04)0.0102780 (47.22)6932 (56.64)＜0.001Male3525 (46.04)5034 (46.82)652 (48.66)4796 (44.96)3107 (52.78)5307 (43.36)EthnicityOthers57 (0.74)105 (0.98)0.09722 (1.64)120 (1.13)0.09951 (0.87)108 (0.88)0.915Han7595 (99.26)10641 (99.02)1317 (98.36)10539 (98.87)5833 (99.13)12128 (99.12)Education levelPrimary school or below4081 (53.35)4052 (37.72)＜0.001617 (46.08)4515 (42.38)0.0312392 (40.66)5613 (45.89)＜0.001Middle school3303 (43.18)5805 (54.04)629 (46.98)5394 (50.63)3086 (52.46)5892 (48.17)College or above266 (3.48)886 (8.25)93 (6.95)745 (6.99)405 (6.88)727 (5.94)Marital statusSeparated/divorced/widowed714 (9.33)498 (4.64)＜0.001131 (9.78)775 (7.27)＜0.001355 (6.03)833 (6.81)＜0.001Single147 (1.92)711 (6.62)26 (1.94)559 (5.25)265 (4.5)576 (4.71)Married or cohabit6791 (88.75)9535 (88.75)1182 (88.27)9323 (87.48)5264 (89.46)10825 (88.48)OccupationOthers3384 (44.23)5249 (48.85)＜0.001749 (55.94)5281 (49.55)＜0.0012878 (48.92)5621 (45.94)＜0.001Farmer4267 (55.77)5496 (51.15)590 (44.06)5376 (50.45)3005 (51.08)6614 (54.06)Age (year)57.92 ± 11.7947.02 ± 13.6658.18 ± 12.0050.68 ± 14.1651.81 ± 13.7851.45 ± 14.0518–441020 (13.32)4652 (43.27)＜0.001175 (13.06)3589 (33.64)＜0.0011773 (30.12)3797 (31.02)0.46445–593137 (40.97)4195 (39.02)550 (41.04)4182 (39.2)2369 (40.24)4864 (39.74)≥603499 (45.70)1905 (17.72)615 (45.9)2897 (27.16)1745 (29.64)3578 (29.23)Family income (RMB)<5000358 (8.83)290 (5.66)＜0.00130 (6.32)247 (6.38)0.725204 (6.74)437 (7.31)0.7165000–9999383 (9.45)370 (7.22)39 (8.21)263 (6.79)244 (8.06)490 (8.19)10000–19999726 (17.91)801 (15.63)68 (14.32)566 (14.62)516 (17.05)985 (16.47)≥200002586 (63.80)3664 (71.49)338 (71.16)2796 (72.21)2062 (68.14)4069 (68.03)Cigarette smokingNever2753 (25.61)1761 (23.00)＜0.0012597 (24.35)273 (20.37)＜0.0012769 (22.62)1664 (28.27)＜0.001Daily smoking247 (2.30)202 (2.64)247 (2.32)32 (2.39)291 (2.38)149 (2.53)Non-daily smoking451 (4.20)518 (6.77)479 (4.49)120 (8.96)595 (4.86)362 (6.15)Ex-smoking7297 (67.89)5175 (67.59)7341 (68.84)915 (68.28)8584 (70.14)3712 (63.05)Alcohol drinkingNever1805 (16.80)1197 (15.63)＜0.0011492 (13.99)166 (12.39)0.0281914 (15.64)1045 (17.75)＜0.001Drinking in the past 12 months1516 (14.11)753 (9.84)1512 (14.18)165 (12.31)1412 (11.54)826 (14.03)Drinking in the past 1 month7425 (69.10)5706 (74.53)7659 (71.83)1009 (75.30)8912 (72.82)4016 (68.22)Central obesityNo2701 (35.47)5777 (54.77)＜0.001362 (27.28)5047 (47.61)＜0.0011800 (30.72)6610 (54.34)＜0.001Yes4913 (64.53)4771 (45.23)965 (72.72)5554 (52.39)4060 (69.28)5554 (45.66)BMI groupsNormal body weight2858 (37.52)5750 (54.52)＜0.001440 (33.16)5227 (49.31)＜0.0011932 (32.97)6613 (54.36)＜0.001Underweight138 (1.81)402 (3.81)23 (1.73)334 (3.15)59 (1.01)475 (3.9)Overweight3084 (40.49)3450 (32.71)567 (42.73)3735 (35.23)2584 (44.1)3900 (32.06)Obesity1537 (20.18)945 (8.96)297 (22.38)1305 (12.31)1285 (21.93)1178 (9.68)Daily salt intake (g)<62809 (38.46)4195 (41.28)＜0.001548 (44.05)4229 (43.05)0.5032363 (42.36)4518 (38.88)＜0.001>64495 (61.54)5967 (58.72)696 (55.95)5594 (56.95)3215 (57.64)7101 (61.12)Daily consumption of vegetable and fruit (g)>4002972 (39.54)5101 (47.99)＜0.001705 (52.61)5710 (53.54)0.5192652 (45.65)5307 (44)0.038<4004545 (60.46)5528 (52.01)635 (47.39)4954 (46.46)3158 (54.35)6755 (56)Daily red meat intake (g)<1005846 (94.92)8429 (93.20)＜0.0011240 (92.54)9936 (93.17)0.3874490 (92.75)9589 (94.38)＜0.001>100313 (5.08)615 (6.80)100 (7.46)728 (6.83)351 (7.25)571 (5.62)


## 3.2. Cluster Analysis of Hypertension, Diabetes, and Dyslipidemia

The results showed that the number of people with three diseases accounted for 2.33%, and the number of people with hypertension and diabetes, hypertension and dyslipidemia, and diabetes and dyslipidemia accounted for 4.58%, 15.60%, and 3.57%, respectively (Figure1).Figure 1
The overlap of hypertension, diabetes, and dyslipidemia in Northwest China.Note. A is hypertension, B is diabetes, and C is dyslipidemia. The percentages shown in each part of the figure are the proportion of the diseases in the population.


## 3.3. Risk Factor Analysis

### 3.3.1. Risk Factors of Hypertension

The results in model I showed that there were no association between family average annual income, smoking, daily average red meat intake, and hypertension (P>0.200). The rest of the risk factors in Table 1 are included in model II, the results showed that gender, age, alcohol consumption, central obesity, overweight and obesity, insufficient daily intake of vegetables and fruits, diabetes, and dyslipidemia were associated with hypertension. Those who were 45–59 years old and 60 years old and above were 2.78 times (95% CI 2.475–3.116) and 6.948 times (95% CI 6.107–7.905) prone to have hypertension than those at 18–44 years old, respectively. Overweight and obesity were 1.66 times (95% CI 1.489–1.858) and 3.094 times (95% CI) to have hypertension than those with normal weight, respectively. Participants with diabetes were 1.82 times (95% CI 1.586–2.085) to have hypertension than those without. And that was 1.247 times (95% CI 1.133–1.371) in participants with dyslipidemia. Participants in rural areas, graduated from middle school, junior college or above, unmarried or married and cohabitation, and low weight were less likely to having hypertension (Table 3).Table 3
Logistic regression analysis on risk factors of hypertension among adults from northwest China.
VariablesModel IModel IIOR (95% CI)POR (95% CI)PResidencyRural0.836 (0.716–0.975)0.0230.906 (0.826–0.995)0.039SexMale1.260 (1.033–1.536)0.0231.106 (1.003–1.219)0.042EthnicityHan1.628 (0.917–2.890)0.0961.294 (0.843–1.985)0.238Education levelMiddle school0.823 (0.712–0.952)0.0090.801 (0.729–0.880)＜0.001College or above0.560 (0.393–0.799)0.0010.574 (0.461–0.714)＜0.001Marital statusSingle0.546 (0.322–0.924)0.0240.557 (0.409–0.758)＜0.001Married or cohabit0.709 (0.536–0.938)0.0160.811 (0.690–0.954)0.011OccupationFarmer1.090 (0.941–1.264)0.251Age (year)45–592.582 (2.141–3.113)＜0.0012.777 (2.475–3.116)＜0.001≥606.158 (5.013–7.565)＜0.0016.948 (6.107–7.905)＜0.001Family income (RMB)5000–99991.000 (0.696–1.435)0.99910000–199991.186 (0.863–1.630)0.292≥200001.080 (0.815–1.431)0.591Cigarette smokingDaily smoking0.944 (0.759–1.175)0.606Non-daily smoking1.269 (0.790–2.037)0.325Ex-smoking0.973 (0.702–1.349)0.871Alcohol drinkingDrinking in the past 12 months0.752 (0.587–0.963)0.3470.780 (0.678–0.896)0.833Drinking in the past 1 month0.912 (0.752–1.105)0.0241.014 (0.889–1.158)＜0.001Central obesityYes1.384 (1.168–1.639)＜0.0011.383 (1.239–1.544)＜0.001BMI groupsUnderweight0.532 (0.322–0.876)0.0130.559 (0.414–0.753)＜0.001Overweight1.597 (1.348–1.892)＜0.0011.663 (1.489–1.858)＜0.001Obesity2.805 (2.207–3.566)＜0.0013.094 (2.653–3.609)＜0.001Daily salt intake (g)>61.161 (1.007–1.338)0.0401.050 (0.961–1.148)0.282Daily consumption of vegetables and fruits (g)<4001.152 (1.005–1.322)0.0431.273 (1.167–1.389)＜0.001Daily red meat intake (g)>1000.954 (0.664–1.371)0.800DiabetesYes2.207 (1.754–2.777)＜0.0011.818 (1.586–2.085)＜0.001DyslipidemiaYes1.227 (1.057–1.423)0.0071.247 (1.133–1.371)＜0.001Note. In model I, hypertension is taken as dependent variable; residency, age, sex, ethnicity, education level, marital status, occupation, family income, smoking, drinking, central obesity, BMI groups, salt intake, vegetable and fruit consumption, red meat intake, diabetes, and dyslipidemia are taken as independent variables. In model II, we further excluded family average annual income, smoking, and daily red meat intake, as their P>0.20 in model I.


### 3.3.2. Risk Factors of Diabetes

The results in model II showed that gender, age, daily smoking, central obesity, overweight and obesity, hypertension, and dyslipidemia were associated with diabetes. Those who were 45–59 years old and 60 years old and above were 2.357 times (95% CI 1.952–2.847) and 3.521 times (95% CI 2.894–4.285) prone to have risk of diabetes than those who were 18–44 years old, respectively. Those who were overweight and obesity were 1.206 times (95% CI 1.028–1.415) and 1.565 times (95% CI 1.284–1.907) to have the risk of diabetes than those with normal weight, respectively. Participants with hypertension or dyslipidemia were 1.761 times (95% CI 1.546–2.006) and 1.934 times (95% CI 1.708–2.189) to get diabetes than those without them, respectively. Farmers and those who were living in rural areas were less likely to get diabetes (Table4).Table 4
Logistic regression analysis on risk factors of diabetes among adults from northwest China.
VariablesModel IModel IIOR (95% CI)POR (95% CI)PResidencyRural0.743 (0.589–0.938)0.0120.706 (0.621–0.803)＜0.001SexMale1.256 (0.939–1.679)0.1241.351 (1.148–1.588)＜0.001EthnicityHan0.927 (0.457–1.881)0.833Education levelMiddle school1.006 (0.804–1.260)0.955College or above1.355 (0.817–2.248)0.239Marital statusSingle0.488 (0.180–1.325)0.1590.685 (0.430–1.090)0.110Married or cohabit0.893 (0.617–1.293)0.5490.950 (0.770–1.171)0.628OccupationFarmer0.740 (0.591–0.926)0.0090.783 (0.689–0.891)＜0.001Age (year)45–592.723 (1.886–3.931)＜0.0012.357 (1.952–2.847)＜0.001≥604.075 (2.794–5.942)＜0.0013.521 (2.894–4.285)＜0.001Family income (RMB)5000–99991.310 (0.766–2.242)0.32410000–199991.099 (0.676–1.786)0.703≥200001.107 (0.719–1.704)0.644Cigarette smokingDaily smoking1.104 (0.720–1.694)0.0831.217 (0.946–1.566)＜0.001Non-daily smoking0.940 (0.467–1.890)0.8620.895 (0.594–1.347)0.594Ex-smoking0.749 (0.540–1.039)0.6490.715 (0.592–0.864)0.126Alcohol drinkingDrinking in the past 12 months0.938 (0.699–1.260)0.672Drinking in the past 1 month1.013 (0.700–1.464)0.947Central obesityYes1.627 (1.226–2.159)0.0011.456 (1.234–1.717)＜0.001BMI groups underweight0.919 (0.360–2.350)0.8601.151 (0.736–1.800)0.538Overweight1.153 (0.884–1.504)0.2931.206 (1.028–1.415)0.022Obesity1.411 (1.016–1.958)0.0401.565 (1.284–1.907)＜0.001Daily salt intake (g)>60.924 (0.744–1.147)0.475Daily consumption of vegetable and fruit (g)<4000.968 (0.786–1.193)0.763Daily red meat intake (g)>1001.262 (0.744–2.138)0.388HypertensionYes2.206 (1.753–2.777)＜0.0011.761 (1.546–2.006)＜0.001DyslipidemiaYes2.010 (1.630–2.478)＜0.0011.934 (1.708–2.189)＜0.001Note. In model I, hypertension is taken as dependent variable; residency, age, sex, ethnicity, education level, marital status, occupation, family income, smoking, drinking, central obesity, BMI groups, salt intake, vegetable and fruit consumption, red meat intake, diabetes, and dyslipidemia are taken as independent variables. In model II, we further excluded ethnicity, education level, family income, drinking, salt intake, daily red meat intake, and red meat intake, as their P>0.20 in model I.


### 3.3.3. Risk Factors of Dyslipidemia

The results in model II showed that gender, education level, daily smoking, drinking, central obesity, overweight and obesity, hypertension, and diabetes were associated with dyslipidemia. Overweight and obesity were 1.579 times (95% CI 1.420–1.755) and 2.285 times (95% CI 1.986–2.628) prone to have the risk of dyslipidemia than those with normal weight, respectively. Those with hypertension were 1.242 times (95% CI 1.134–1.360) prone to have the risk of dyslipidemia than those without it. And that was 1.924 times (95% CI 1.699–2.179) for participants with diabetes. Low body weight was less likely to get dyslipidemia (Table5).Table 5
Logistic regression analysis on risk factors of dyslipidemia among adults from northwest China.
VariablesModel IModel IIOR (95% CI)POR (95% CI)PResidencyRural0.927 (0.792–1.085)0.343SexMale1.245 (1.018–1.522)0.0331.401 (1.245–1.576)＜0.001EthnicityHan0.621 (0.365–1.057)0.0791.031 (0.709–1.500)0.872Education levelMiddle school1.166 (1.004–1.354)0.0441.174 (1.072–1.286)0.001College or above1.096 (0.790–1.522)0.5831.377 (1.155–1.642)＜0.001Marital statusSingle1.078 (0.658–1.766)0.766Married or cohabit1.047 (0.786–1.395)0.753OccupationFarmer1.022 (0.878–1.189)0.777Age (year)45–590.814 (0.677–0.977)0.0270.910 (0.820–1.009)0.075≥600.799 (0.650–0.983)0.0340.917 (0.813–1.036)0.164Family income (RMB)5000–99990.874 (0.596–1.283)0.49310000–199991.061 (0.762–1.478)0.726≥200001.065 (0.793–1.430)0.677Cigarette smokingDaily smoking1.309 (1.048–1.635)0.0181.287 (1.130–1.467)＜0.001Non-daily smoking0.873 (0.533–1.430)0.5900.907 (0.680–1.209)0.505Ex-smoking1.169 (0.842–1.624)0.3500.988 (0.805–1.212)0.906Alcohol drinkingDrinking in the past 12 months0.855 (0.665–1.099)0.0071.034 (0.910–1.175)0.041Drinking in the past 1 month0.764 (0.628–0.929)0.2220.874 (0.769–0.994)0.611Central obesityYes1.683 (1.410–2.010)＜0.0011.952 (1.754–2.172)＜0.001BMI groups underweight0.347 (0.159–0.760)0.0080.565 (0.403–0.793)0.001Overweight1.778 (1.497–2.113)＜0.0011.579 (1.420–1.755)＜0.001Obesity2.940 (2.339–3.696)＜0.0012.285 (1.986–2.628)＜0.001Daily salt intake (g)>61.018 (0.880–1.177)0.812Daily consumption of vegetable and fruit (g)<4001.054 (0.917–1.213)0.459Daily red meat intake (g)>1000.698 (0.482–1.011)0.0571.097 (0.935–1.287)0.257HypertensionYes1.210 (1.042–1.404)0.0121.242 (1.134–1.360)＜0.001DiabetesYes1.997 (1.619–2.462)＜0.0011.924 (1.699–2.179)＜0.001Note. In model I, hypertension is taken as dependent variable; residency, age, sex, ethnicity, education level, marital status, occupation, family income, smoking, drinking, central obesity, BMI groups, salt intake, vegetable and fruit consumption, red meat intake, diabetes, and dyslipidemia are taken as independent variables. In model II, we further excluded residency, marital status, occupation, family income, salt intake, daily red meat intake, and red meat intake, as their P>0.20 in model I.


## 3.3.1. Risk Factors of Hypertension

The results in model I showed that there were no association between family average annual income, smoking, daily average red meat intake, and hypertension (P>0.200). The rest of the risk factors in Table 1 are included in model II, the results showed that gender, age, alcohol consumption, central obesity, overweight and obesity, insufficient daily intake of vegetables and fruits, diabetes, and dyslipidemia were associated with hypertension. Those who were 45–59 years old and 60 years old and above were 2.78 times (95% CI 2.475–3.116) and 6.948 times (95% CI 6.107–7.905) prone to have hypertension than those at 18–44 years old, respectively. Overweight and obesity were 1.66 times (95% CI 1.489–1.858) and 3.094 times (95% CI) to have hypertension than those with normal weight, respectively. Participants with diabetes were 1.82 times (95% CI 1.586–2.085) to have hypertension than those without. And that was 1.247 times (95% CI 1.133–1.371) in participants with dyslipidemia. Participants in rural areas, graduated from middle school, junior college or above, unmarried or married and cohabitation, and low weight were less likely to having hypertension (Table 3).Table 3
Logistic regression analysis on risk factors of hypertension among adults from northwest China.
VariablesModel IModel IIOR (95% CI)POR (95% CI)PResidencyRural0.836 (0.716–0.975)0.0230.906 (0.826–0.995)0.039SexMale1.260 (1.033–1.536)0.0231.106 (1.003–1.219)0.042EthnicityHan1.628 (0.917–2.890)0.0961.294 (0.843–1.985)0.238Education levelMiddle school0.823 (0.712–0.952)0.0090.801 (0.729–0.880)＜0.001College or above0.560 (0.393–0.799)0.0010.574 (0.461–0.714)＜0.001Marital statusSingle0.546 (0.322–0.924)0.0240.557 (0.409–0.758)＜0.001Married or cohabit0.709 (0.536–0.938)0.0160.811 (0.690–0.954)0.011OccupationFarmer1.090 (0.941–1.264)0.251Age (year)45–592.582 (2.141–3.113)＜0.0012.777 (2.475–3.116)＜0.001≥606.158 (5.013–7.565)＜0.0016.948 (6.107–7.905)＜0.001Family income (RMB)5000–99991.000 (0.696–1.435)0.99910000–199991.186 (0.863–1.630)0.292≥200001.080 (0.815–1.431)0.591Cigarette smokingDaily smoking0.944 (0.759–1.175)0.606Non-daily smoking1.269 (0.790–2.037)0.325Ex-smoking0.973 (0.702–1.349)0.871Alcohol drinkingDrinking in the past 12 months0.752 (0.587–0.963)0.3470.780 (0.678–0.896)0.833Drinking in the past 1 month0.912 (0.752–1.105)0.0241.014 (0.889–1.158)＜0.001Central obesityYes1.384 (1.168–1.639)＜0.0011.383 (1.239–1.544)＜0.001BMI groupsUnderweight0.532 (0.322–0.876)0.0130.559 (0.414–0.753)＜0.001Overweight1.597 (1.348–1.892)＜0.0011.663 (1.489–1.858)＜0.001Obesity2.805 (2.207–3.566)＜0.0013.094 (2.653–3.609)＜0.001Daily salt intake (g)>61.161 (1.007–1.338)0.0401.050 (0.961–1.148)0.282Daily consumption of vegetables and fruits (g)<4001.152 (1.005–1.322)0.0431.273 (1.167–1.389)＜0.001Daily red meat intake (g)>1000.954 (0.664–1.371)0.800DiabetesYes2.207 (1.754–2.777)＜0.0011.818 (1.586–2.085)＜0.001DyslipidemiaYes1.227 (1.057–1.423)0.0071.247 (1.133–1.371)＜0.001Note. In model I, hypertension is taken as dependent variable; residency, age, sex, ethnicity, education level, marital status, occupation, family income, smoking, drinking, central obesity, BMI groups, salt intake, vegetable and fruit consumption, red meat intake, diabetes, and dyslipidemia are taken as independent variables. In model II, we further excluded family average annual income, smoking, and daily red meat intake, as their P>0.20 in model I.


## 3.3.2. Risk Factors of Diabetes

The results in model II showed that gender, age, daily smoking, central obesity, overweight and obesity, hypertension, and dyslipidemia were associated with diabetes. Those who were 45–59 years old and 60 years old and above were 2.357 times (95% CI 1.952–2.847) and 3.521 times (95% CI 2.894–4.285) prone to have risk of diabetes than those who were 18–44 years old, respectively. Those who were overweight and obesity were 1.206 times (95% CI 1.028–1.415) and 1.565 times (95% CI 1.284–1.907) to have the risk of diabetes than those with normal weight, respectively. Participants with hypertension or dyslipidemia were 1.761 times (95% CI 1.546–2.006) and 1.934 times (95% CI 1.708–2.189) to get diabetes than those without them, respectively. Farmers and those who were living in rural areas were less likely to get diabetes (Table4).Table 4
Logistic regression analysis on risk factors of diabetes among adults from northwest China.
VariablesModel IModel IIOR (95% CI)POR (95% CI)PResidencyRural0.743 (0.589–0.938)0.0120.706 (0.621–0.803)＜0.001SexMale1.256 (0.939–1.679)0.1241.351 (1.148–1.588)＜0.001EthnicityHan0.927 (0.457–1.881)0.833Education levelMiddle school1.006 (0.804–1.260)0.955College or above1.355 (0.817–2.248)0.239Marital statusSingle0.488 (0.180–1.325)0.1590.685 (0.430–1.090)0.110Married or cohabit0.893 (0.617–1.293)0.5490.950 (0.770–1.171)0.628OccupationFarmer0.740 (0.591–0.926)0.0090.783 (0.689–0.891)＜0.001Age (year)45–592.723 (1.886–3.931)＜0.0012.357 (1.952–2.847)＜0.001≥604.075 (2.794–5.942)＜0.0013.521 (2.894–4.285)＜0.001Family income (RMB)5000–99991.310 (0.766–2.242)0.32410000–199991.099 (0.676–1.786)0.703≥200001.107 (0.719–1.704)0.644Cigarette smokingDaily smoking1.104 (0.720–1.694)0.0831.217 (0.946–1.566)＜0.001Non-daily smoking0.940 (0.467–1.890)0.8620.895 (0.594–1.347)0.594Ex-smoking0.749 (0.540–1.039)0.6490.715 (0.592–0.864)0.126Alcohol drinkingDrinking in the past 12 months0.938 (0.699–1.260)0.672Drinking in the past 1 month1.013 (0.700–1.464)0.947Central obesityYes1.627 (1.226–2.159)0.0011.456 (1.234–1.717)＜0.001BMI groups underweight0.919 (0.360–2.350)0.8601.151 (0.736–1.800)0.538Overweight1.153 (0.884–1.504)0.2931.206 (1.028–1.415)0.022Obesity1.411 (1.016–1.958)0.0401.565 (1.284–1.907)＜0.001Daily salt intake (g)>60.924 (0.744–1.147)0.475Daily consumption of vegetable and fruit (g)<4000.968 (0.786–1.193)0.763Daily red meat intake (g)>1001.262 (0.744–2.138)0.388HypertensionYes2.206 (1.753–2.777)＜0.0011.761 (1.546–2.006)＜0.001DyslipidemiaYes2.010 (1.630–2.478)＜0.0011.934 (1.708–2.189)＜0.001Note. In model I, hypertension is taken as dependent variable; residency, age, sex, ethnicity, education level, marital status, occupation, family income, smoking, drinking, central obesity, BMI groups, salt intake, vegetable and fruit consumption, red meat intake, diabetes, and dyslipidemia are taken as independent variables. In model II, we further excluded ethnicity, education level, family income, drinking, salt intake, daily red meat intake, and red meat intake, as their P>0.20 in model I.


## 3.3.3. Risk Factors of Dyslipidemia

The results in model II showed that gender, education level, daily smoking, drinking, central obesity, overweight and obesity, hypertension, and diabetes were associated with dyslipidemia. Overweight and obesity were 1.579 times (95% CI 1.420–1.755) and 2.285 times (95% CI 1.986–2.628) prone to have the risk of dyslipidemia than those with normal weight, respectively. Those with hypertension were 1.242 times (95% CI 1.134–1.360) prone to have the risk of dyslipidemia than those without it. And that was 1.924 times (95% CI 1.699–2.179) for participants with diabetes. Low body weight was less likely to get dyslipidemia (Table5).Table 5
Logistic regression analysis on risk factors of dyslipidemia among adults from northwest China.
VariablesModel IModel IIOR (95% CI)POR (95% CI)PResidencyRural0.927 (0.792–1.085)0.343SexMale1.245 (1.018–1.522)0.0331.401 (1.245–1.576)＜0.001EthnicityHan0.621 (0.365–1.057)0.0791.031 (0.709–1.500)0.872Education levelMiddle school1.166 (1.004–1.354)0.0441.174 (1.072–1.286)0.001College or above1.096 (0.790–1.522)0.5831.377 (1.155–1.642)＜0.001Marital statusSingle1.078 (0.658–1.766)0.766Married or cohabit1.047 (0.786–1.395)0.753OccupationFarmer1.022 (0.878–1.189)0.777Age (year)45–590.814 (0.677–0.977)0.0270.910 (0.820–1.009)0.075≥600.799 (0.650–0.983)0.0340.917 (0.813–1.036)0.164Family income (RMB)5000–99990.874 (0.596–1.283)0.49310000–199991.061 (0.762–1.478)0.726≥200001.065 (0.793–1.430)0.677Cigarette smokingDaily smoking1.309 (1.048–1.635)0.0181.287 (1.130–1.467)＜0.001Non-daily smoking0.873 (0.533–1.430)0.5900.907 (0.680–1.209)0.505Ex-smoking1.169 (0.842–1.624)0.3500.988 (0.805–1.212)0.906Alcohol drinkingDrinking in the past 12 months0.855 (0.665–1.099)0.0071.034 (0.910–1.175)0.041Drinking in the past 1 month0.764 (0.628–0.929)0.2220.874 (0.769–0.994)0.611Central obesityYes1.683 (1.410–2.010)＜0.0011.952 (1.754–2.172)＜0.001BMI groups underweight0.347 (0.159–0.760)0.0080.565 (0.403–0.793)0.001Overweight1.778 (1.497–2.113)＜0.0011.579 (1.420–1.755)＜0.001Obesity2.940 (2.339–3.696)＜0.0012.285 (1.986–2.628)＜0.001Daily salt intake (g)>61.018 (0.880–1.177)0.812Daily consumption of vegetable and fruit (g)<4001.054 (0.917–1.213)0.459Daily red meat intake (g)>1000.698 (0.482–1.011)0.0571.097 (0.935–1.287)0.257HypertensionYes1.210 (1.042–1.404)0.0121.242 (1.134–1.360)＜0.001DiabetesYes1.997 (1.619–2.462)＜0.0011.924 (1.699–2.179)＜0.001Note. In model I, hypertension is taken as dependent variable; residency, age, sex, ethnicity, education level, marital status, occupation, family income, smoking, drinking, central obesity, BMI groups, salt intake, vegetable and fruit consumption, red meat intake, diabetes, and dyslipidemia are taken as independent variables. In model II, we further excluded residency, marital status, occupation, family income, salt intake, daily red meat intake, and red meat intake, as their P>0.20 in model I.


## 4. Discussion

In the past 30 years, the increase of incidence and prevalence of hypertension, diabetes, and dyslipidemia in China has resulted in the growth of burden of these three diseases [9]. With the rapid economic development, changes in people's lifestyle and eating habits and the accelerated aging of the population, cardiovascular, and cerebrovascular diseases have become the first mortality among Chinese residents currently. It is well documented that hypertension, diabetes, and dyslipidemia are significant risk factors for cardiovascular and cerebrovascular diseases [9, 10]. It is of great significance to estimate the prevalence of these three diseases in Western China and explore their risk factors for the prevention and control of chronic diseases in Northwest China.According to this study, the prevalence of hypertension in northwest China (41.59%, age-standardized 29.31%) was higher than that of overall China (23.5%) in 2015. And, the prevalence of diabetes (11.16%, age-standardized 7.94%) and dyslipidemia (32.48%, age-standardized 31.54%) was lower than that of overall China in 2013 and in 2015, respectively. Due to diversities of regions, lifestyles, and eating habits, the disease prevalence in Northwest China is different from the national average. The prevalence of diabetes and dyslipidemia in rural areas was higher than that in urban areas. The possible reasons might be the insufficient distribution of health resources in rural areas in northwest China, the scattered residence in mountains with inconvenient transportation, and the relatively low education level of the local residents. They all resulted to the rural residents having less knowledge on the prevention and treatment of chronic diseases and did not pay attention to information on health [11]. The prevalence of hypertension, diabetes, and dyslipidemia among residents with low education background (middle school and below) was higher than that of college students and above. This may be because the health awareness and healthy lifestyle were related to the education level. The awareness is relatively weak, and healthy lifestyles were not easy to be developed among people with low education level [10, 11]. The prevalence of hypertension and diabetes in middle-aged and elderly people was higher than that in the young people. On the one hand, it may be vascular sclerosis and decreased elasticity with the increase of age [12]; on the other hand, the elderly people exposed to more health examination than young people because of having many diseases enhanced the detection rate.The study showed that men were more likely than women to have hypertension, diabetes, and dyslipidemia, which was related to unhealthy lifestyle and diets among men. The majority of men smoked and drank and liked to have greasy food, and they had abdominal obesity [13]. The risk to have hypertension and diabetes was associated with older age, which may be related to the fact that the middle-aged and elderly people were more vulnerable to multiple chronic diseases including hypertension, diabetes, and their complications due to the decline of physical function [14]. Central obesity, overweight, and obesity were risk factors for hypertension, diabetes, and dyslipidemia. These three diseases were also related to higher BMI. This is consistent with the studies in other areas of China [11–13]. It is suggested that the main interventions to prevent the occurrence of chronic diseases are to advocate residents to adhere to regular physical exercise, to watch weight changes, and to carry out health education on diet with low salt, low fat, and low oil. This way will help residents to develop a healthy lifestyle, improve the lipid metabolism, and maintain a healthy body weight [14]. Daily smoking is a risk factor for diabetes and dyslipidemia. Drinking is a risk factor for hypertension and dyslipidemia. It demonstrated in this study that those who are male, daily smoking, drinking, central obesity, overweight, and obesity are the high-risk population in prevention and control of hypertension, diabetes. and dyslipidemia in western China.The World Health Organization (WHO) defined 2 or more chronic diseases in the same patient for more than 6 months as comorbidity in 2008, which increased the risk of death, hospitalization, disability, depression, and economic expenditure [15, 16]. Research showed that hypertension, diabetes, and other diseases were often regarded as the key diseases of comorbidity [17]. The study found that 2.33% of the participants had hypertension, diabetes, and dyslipidemia at the same time. The comorbidity of hypertension and dyslipidemia (15.60%) was much higher than that of hypertension and diabetes (4.58%) or diabetes and dyslipidemia (3.57%). This is consistent with that of the study in Nanchong in China, which may be related to the prevalence of hypertension being higher than that of diabetes or dyslipidemia. The study showed that hypertension, diabetes, and dyslipidemia are linked to each other, suggesting that interactions of these three diseases on population health should be noticed. Hypertension affected the blood lipid metabolism and resulted in dyslipidemia further. Meanwhile, dyslipidemia increased the variability of blood pressure. The blood lipid level and blood pressure were associated and affected each other [18]. Insufficient insulin secretion stimulated fatty acids released in the human body. Dyslipidemia and diabetes could largely increase the risk of cardiovascular disease and mortality [19]. Therefore, it is necessary to control and prevent the risk factors of these three diseases in order to reduce the risk of cardiovascular and cerebrovascular events.In conclusion, chronic diseases affected the health of the population in Northwest China. To reduce the prevalence and mortality of chronic diseases such as cardiovascular and cerebrovascular diseases, it is necessary to monitor metabolic indicators such as blood pressure, blood lipid, and blood glucose and take measures to prevent and control the hypertension, diabetes, dyslipidemia, and obesity [18, 19]. Community management of chronic disease is the main mode in Northwest China. The prevention and control system of the state, province, city, county, and township/community can be used to carry out interventions on prevention, control, and education based on the characteristics of different groups of people, so as to promote the healthy lifestyle and reduce the occurrence of risk factors [20]. First, primary care health service institutions should combine with the national basic public health service to strengthen the management of residents’ blood pressure, blood sugar, and blood lipid and to guide the rational drug use. Second, it is suggested that the health institutions should carry out health education on knowledge of chronic disease prevention and control and advocate residents to promote physical activity and keep balanced diet. Third, we could find the key population by early screening to intervene the main risk factors and further to control the occurrence and development of chronic diseases by taking comprehensive measures. Fourth, it is suggested to establish cooperation between community health service centers/township health centers and higher-level general hospitals to give guidance and treatment to high-risk groups [21].The prevalence, comorbidity, and risk factors of hypertension, diabetes, and dyslipidemia from this study could provide basic information for chronic disease prevention and control in northwest China. However, there are several limitations in this study. First, the relatively high proportion of elderly participants might lead to a high prevalence of the three diseases, for age is a risk factor for diseases such as hypertension and diabetes; second, the correlation between physical activity and the three diseases was not considered in this study, which should be studied further.



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*Source: 5528007-2021-04-12.xml*