…the avian auditory forebrain (e.g. see Wild et al., 1993) consist of a large number of small, densely packed somata with average diameters in the range of 5±7 mm (Saini & Leppelsack, 1981; Hose et al., 1987) preventing the isolation of single units in the current study with freely moving animals.

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Flat cranial base: Numerous workers have documented the open cranial base angle (platybasia) of DS individuals compared with euploid controls [49, 58, 59, 80, 81].

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In general, patients with hypertension, diabetes mellitus, or end-stage renal disease on hemodialysis are likely to have PPH (Jansen and Lipsitz 1995).

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The Simulated Annealing approach has been proven to be very effective when applied to non convex optimization, for which gradient based algorithms may fail to produce good solutions, Cerný (1985); Marques et al. (1991); A.

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If the generating function has up to a finite number of zeros, the use of multigrid methods is significantly more efficient [7,5] .

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Matthews et al. (2002) determined that 3–4 days monitoring were required to accurately measure MVPA [5].

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Lennard-Jones interactions were evaluated using a straight 1.2 nm cutoff for Gromos53A6, Gromos54A7, and Berger and a 1.0 nm cutoff for OPLS.

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has shown distractor suppression to have a much larger effect on capacity than target selection processes (Bettencourt & Somers, 2009; Pylyshyn, 2006; Vogel et al., 2005; Zanto & Gazzaley, 2009), and as the effect on capacity of increasing the number of distractors is correlated between VSTM and MOT tasks, we believe that the resources consumed by

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Despite the inconsistencies in the literature, CVP of 8 mmHg or greater (1, 2, 4) and up to 15 mmHg (14) has been advocated as end points of fluid resuscitation with some success, but these treatments are part of Bbundled care[ (i.

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Among these, nanocarbons are now considered the most promising fillers for the development of high performance materials [28–34].

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In other amidohydrolases, titration of the apoprotein with the metal ion resulted in rapid binding and a linear relationship between enzymatic activity and the amount of metal added (20, 22, 35).

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The results are given in Table 2, where each row refers to the set of tRNA genes for a given amino acid, and each column (from left to right) depicts an increasing number of positions used by CART for predicting the tRNAs’ cognate amino acid identity.

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Recent publications investigated six healthy volunteers who were administered magnetically labeled extended-release tablets containing felodipine under fasting and fed conditions [8,15–17].

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ous studies have shown that BMP signaling stimulates Indian hedgehog (Ihh) expression, which in turn increases expression of PTHrP [22,23].

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…automatically generates layout information encoding node and reaction centroid coordinates using the FruchtermanReingold (FR) algorithm, which has been shown to be robust in the face of variegated graph topologies and faithfully reproduces the underlying symmetry [Fruchterman and Reingold, 1991].

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Thus, the most plausible interpretation of the results obtained in the present work is that the nuclear gene activity plays an important role in the phenotypic manifestation of the MERRF mutation (Lertrit et al., 1992), as has been shown for other disease-causing mtDNA mutations (Harding et al.

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The value of Ea for the pulmonary circulation found here is approximately fourfold lower than the value of Ea for the systemic vasculature of mice published previously (13, 41, 53, 62).

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14 unique from political ideologies such as social dominance orientation, right-wing authoritarianism, and conservatism, previously shown to be associated with dehumanization (e.g., Costello & Hodson, 2010, 2014; Hodson & Costello, 2007; Kteily et al., 2015) and aggressive intergroup attitudes (e.

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Earlier investigations in Cebu Longitudinal Health and Nutrition Survey (CLHNS) samples showed convincing evidence of the role of exposure to a pathogenic environment in predicting plasma CRP levels in Filipinos [9, 10].

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Recently, peptide fragmentation with tandem mass spectrometry parallel to the standardized MALDI-TOF-MS has emerged as an additional tool which provides enhanced capabilities for peptide sequencing directly from samples such as nervous tissues or even single cells of invertebrates, including those of insects (e.g., Yew et al., 2003; Billimoria et al., 2005; Neupert and Predel, 2005; Nachman et al., 2006; Wegener et al., 2006).

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For example, Brelin et al. (2005) showed that individuals within a population of juvenile brown trout (Salmo trutta) were bimodally divergent in behaviour and sympathetic reactivity.

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Granule cell dispersion is a characteristic structural abnormality in temporal lobe epilepsy (Houser, 1990).

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Some previous studies reported temporal and spatial variations of gaseous and particulate matter pollutants in China (Chai et al., 2014; Chen and Xie, 2014; Han et al., 2009; Johansson et al., 2007; Karar et al., 2006; Lewne et al., 2004; Li et al., 2014; Martini et al., 2015; Meng et al., 2009;…

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Thirty-six peptides with lengths of 9–10mers were designed based on Malaysian circulating DENV strains, using two major histocompatibility complex ligands and peptide motifs databases; SYFPEITHI [17] or RANKPEP [18] (Table S1).

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(28) for selecting k, as given by Items (5,2) in Table 3, which are improved variants of Item (5,1), previously proposed for RBF net with empirical learning (Xu, 1998a).

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…time constants of 280 ns and 300ms led to a unidirectional model of the early photocycle with two different hK states:
hR1 hn ¡ hKE ¡ hKL ¡ hL ¡ · · ·¡ hR
The hKE (early K) and hKL (late K) states were named by analogy with the substates of the early bR photocycle (Dioumaev and Braiman, 1997b).

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…(Figure 4C, left graph, and Figure 4—figure supplement 1), resembling the effect of disrupting mitochondrial fission due to the depletion of Drp1 or INF2 from cells (Bleazard et al., 1999; Labrousse et al., 1999; Wakabayashi et al., 2009; Korobova et al., 2013, 2014; Hatch et al., 2014).

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For example, most of the marine species that had been subdivided by lower sea levels around the Florida Peninsula still show a strong signal of regional structure, indicating that migration over long distances is insufficient to mix haplotype lineages among populations (Avise, 2000).

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For the historical data, intra-individual median LDL-C, HDL-C, TC, and HbA1c were used, and the CV of HbA1c (ratio of intrapersonal HbA1c standard deviation [SD]/mean HbA1c) was utilized as a measure of historical HbA1c variability (Waden et al., 2009).

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In accordance with previous studies (Haas et al., 2002; Houser, 1990) a GCL width of 160 μmandmorewas considered as GCD.

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In the case of aversion towards ambiguity, the observed decrease in reservation value is similar to that in Nishimura and Ozaki (2007).

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Hence, the lethality associated with mutations at the locus was suggested to be due to reduction in wg signaling (Haerry et al. 1997).

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…of non-genic SNPs. Gene classes were defined according to PharmaADME core list and related gene list (pharmaADME.org), CYP genes metabolizing primarily exogenous or endogenous substrates were defined based on information from the literature (Nebert and Russell 2002; Guengerich 2003; Thomas 2007).

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The recovered parameters (Chapter 2) were in
 142
 accordance with those recovered from midazolam and testosterone hydroxylation in single HIM donors (Paine et al., 2004).

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Our approach uses XML [15] to describe accurately multi-level SLAs, as well as to share them among different members of the CloudLend network unambiguously, without the need for any data conversion.

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Studies have shown that response times are faster on trials when there is an expectation of a reward than on trials when there is none (Murray et al. 2008; Pessiglione et al. 2006), reflecting an increased motivation to obtain rewards.

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Wand and Weber [15,16,27] have extended an ontology presented by Bunge [28], and applied it to the modelling of information systems.

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Just by being present in the anemone nonbreeders are potential competitors for reproduction, and they must do something to mitigate this effect given that breeders can evict them (Buston 2003a).

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Adipocyte diameter measurements were performed using Image Pro imaging software (Media Cybernetics, Bethesda, MD), as recently described (16).

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In addition, consistent with the result of our preclinical study, recent clinical study showed that alectinib was also highly active against ALK-positive NSCLC patients after treatment with crizotinib [21].

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…is most likely long lived as the short-
term (cosmogenic nuclide) erosion rates are within the range of long-term (thermochronometry) rates, suggesting that there has been no significant change in exhumation rates in the past few million
years (Safran et al. 2005, 2006; Wittmann et al. 2009).

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When we combine the results of these two studies in pancreatic and gastric cancer patients, we can say that HDL and PON1 levels are lower in cancer patients than in control subjects (Akcay et al., 2003a,b).

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The magnitude of muscle hypertrophy can be variable between-individual components of a muscle group (Narici et al., 1989, 1996; Housh et al., 1992; Norrbrand et al., 2008).

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The circulating HA has also been found to facilitate cancerous cells to escape the immune surveillance [7], and reduce the delivery of chemotherapeutic agents, including doxorubicin, and mitomycin C [10].

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c-Jun-N-Terminal inhibitory kinase JIK and TRAF2 to the stimulated ER stress sensor IRE-1, where TRAF2 can activate ASK-1, an upstream activating kinase of JNK (2) activation of caspase 12, which is released from its

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…are in line with previous research on the use of referential expressions in narratives, which showed similar variations in the use of referential forms linked to different moments or discourse stages (e.g., Van der Lely, 1997; Colle et al., 2008; Hendriks et al., 2014; Contemori and Dussias, 2016).

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Our results suggest that the attractiveness genes may express not only during sexual maturation and reproduction but also during earlier life and their expression has antagonistic effects during the early stage [23, 46].

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Specifically, it appears that Pacific sea surface temperatures (SSTs), especially as expressed by cold tropical temperatures during the La Niña phase of the El Niño Southern Oscillation (ENSO), have the most direct influence, with Atlantic Ocean SSTs perhaps having an indirect influence through dynamic effects on the atmospheric general circulation (Cook et al. 2011; Kushnir et al. 2010; McCrary and Randall 2010).

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There may be many reasons for this bias, not all intentional, but bias can also be indirect, unintentional and ambivalent (Snowden, 2003).

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” This is a highly reliable prognostic marker in colorectal cancer and is currently being investigated for use in other tumor types [24, 28, 29].

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8 illustrates a summary for the comparison with the existing bit-split string matching approaches described in [8], [10], and [4].

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Previous studies applying the Quadruple Process model to the IAT, however, have yielded equivocal results (10, 27, 28).

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In particular, controllers for flying robots have taken inspiration from pheromone communication in ants (Hauert et al., 2008; Kuiper and Nadjm-Tehrani, 2006; Sauter et al., 2005), flocking by birds (Basu et al.

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TCF7L2 (transcription factor 7-like-2) has been previously linked to T2D, and has been cited as one of the most important signals associated with T2D [51].

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Then there have been a wide range of research covering a variety of different schemes for undeniable signatures over the past 15 years [7, 1, 9, 8, 19, 14, 18, 25, 4, 17, 16, 22, 3, 26, 27].

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To train the model, we optimize cross-entropy loss with stochastic gradient descent using minibatched backpropagation through time (BPTT; Rumelhart et al., 1988; Mikolov, 2012); the minibatch size for BPTT, again tuned on the dev set, is set to 9.

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Cognitive impairment is common to both disorders after onset but the magnitude of the impairment seems greater in schizophrenia than in bipolar disorder (22).

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Its work has been published in a number of journals and at several international conferences ([2], [3], [4]).

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ygenase gene, behaved the same way as when challenged with 4-CP (Nordin et al. 2005), i.

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The development of mathematical models for evolution of primary quantities of interest in bioreactor systems, as well as their incorporation into the design process, have the potential to accelerate the path to realization of optimal functional outcomes in engineered tissues; see [1] for a review of modeling approaches.

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Previous work [8, 2, 11] has demonstrated that a lowdimensional subspace can accurately capture the variation in images of a face resulting from arbitrarily complex variations in illumination.

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There exist some other techniques for controlling multivariate processes, such as multi-way PCA [7] (Louwerse and Smilde, 2000) and multi-way PLS [8] (Nomikos and MacGregor, 1995), the application of them is to reducing the dimensionality of the variable space for a multivariate process.

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PtdIns(3,4)P2 was demonstrated to have a higher affinity for Akt than PtdIns(3,4,5)P3, (14), and in accordance with this finding, several studies have shown that reduction of SHIP2 activity may result in decreased, rather then increased, Akt activity, leading to reduced proliferation and enhanced cell death (15,24).

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gondii, or in mice that coxsackievirus-B3-induced viral myocarditis (20, 21, 34).

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It has been postulated that the latter is related to the long evolution of an ACP that leads to a scarring stage [3].

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‚Ä¶leaf litter were transferred into scintillation vials and stored in a solution of ethanol/formalin (70 %/10 % volume,
 which minimized mass loss; Leuven et al. 1985; von Schiller and Solimini 2005) until later identification (generally genus or species level; Tachet et al. 2000; Vieira-Lanero‚Ä¶

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SphK1 inhibition, on the other hand, induces ceramide production and cancer cell apoptosis [30].

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The basic SH3-binding motif 163PPSP165 of human securin locates at the C-terminal region of the protein (UniProt: O95997) and can be elongated to an extended motif 163PPSPVK168, which belongs to the class II SH3 binding motif (PxxPx+, where + refers to a positively charged residue) (12).

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Isolation of cardiomyocytes by standard enzymatic techniques and patch-clamp recordings were performed as described previously [42].

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Since it has been shown that this modification reduces the binding activity of annexin [8], and also, that all four domains present in anxA5 are necessary for optimal binding affinity [9], it is important to ensure that the binding properties of anxA5 are not impaired by these reactions.

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Traumatic events were assessed using the WMH version of the WHO Composite International Diagnostic Interview (CIDI) Version 3.0, a fully structured diagnostic interview administered by trained lay interviewers [21], which includes a screen for traumatic events as part of the module for the diagnosis of PTSD.

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Then, we compare the proposed TTGP method with SVI-GP (Hensman et al. (2013)) on regression tasks and KLSP-GP (Hensman et al.

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Along these zones, actin filaments polymerize, providing the force needed for constriction that floppy ER tubules lack (Korobova et al., 2013, 2014; Hatch et al., 2014).

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The reasons for excluding the toxic endpoints of necrotizing enterocolitis and ROP are that necrotizing enterocolitis and other GI toxicities were proven not to be associated with INDO dose or concentrations [24], and the association of ROP [20] was speculative given the secondary analysis and different treatment populations a priori for different dosing levels used to analyze that aspect of the study [11].

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PX-FERM proteins can then interact with NPxY/NxxY motif containing cargo, and also PDZ binding motif (PDZbm) cargo in the case of SNX27, at the early endosomal membrane (Balana et al., 2011; Bottcher et al., 2012; Cai et al., 2011; Ghai et al., 2013; Ghai et al., 2011; Hayashi et al., 2012; Joubert et al., 2004; Knauth et al., 2005; Lauffer et al., 2010; Lunn et al., 2007; Steinberg et al., 2013; Temkin et al., 2011; Valdes et al., 2011; Wang et al., 2013).

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Interestingly, actin assembly was also recently revealed to take place at the interior of forming autophagosomes, and to be dependent on the phospholipid phosphatidylinositol 3-phosphate (PI(3)P; Mi et al., 2015).

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Finally, MG624 (a selective antagonist for the chick a7 homomeric receptor) binds the chick a7 subtype with a Ki of 106 nM (Gotti et al., 1998; Maggi et al., 1999), but the Ki of its binding to native a6 receptors is 40 times higher.

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The mouse neuronal hybrid cell line MN-1 was cultured and transfected as previously described (Drews et al. 2005), using 50 ng of test plasmid, 10 ng of control plasmid (pRLSV40, Promega), and the Fugene 6 transfection reagent (Roche Molecular Biochemicals, Indianapolis, IN).

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This quiescence of tSCs was surprising because they are normally activated and extend processes when nerve contact is lost (Reynolds and Woolf, 1992; Son and Thompson, 1995b).

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3B), MBD1–3 and MBD5–6 act as two independent structural units and the orientation of MBD1-3 agrees with the data from recent small-angle X-ray scattering (SAXS) experiments (Yu et al. 2017b).

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This observation is highly interesting in light of the known prosurvival effect of sCLU (51) and the fact that high levels of gastrin over prolonged time periods, hypergastrinemia, is known to have a trophic effect on the gastric mucosa (59).

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Frequently, a Vincentizing procedure is used to construct group RT distributions from individual RT distributions (Ratcliff, 1979; Van Zandt, 2000).

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In many documents in medical literature (e.g. MEDLINE), one can find the elements of the PICO structure, but rarely explicitly annotated (Dawes et al., 2007).

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Cell–cell contacts are formed at the adherens junctions (AJs) by intercellular Ca-dependent E-cadherin homodimer formation (Vleminckx and Kemler 1999; Miyoshi and Takai 2005). To assay for the explression of E-cadherin by rat PT cells, immunofluorescence distribution of the protein was investigated on confluent monolayers of WKPT-0293 Cl.2 cells. Monolayers demonstrated the typical pattern of E-cadherin expression at the cell borders (Fig. 1A). Expression of the E-cadherin protein in WKPT-0293 Cl.2 cells was further confirmed by immunoblotting, where Biometals (2007) 20:807–820 811

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…reportedly have bacterial activity which could justify their relevance in treatment of TB. Fabaceae, Asteraceae and Rutaceae families have also been mentioned by several authors to be most used by local communities (Ugulu et al., 2009; Ssegawa and Kasenene, 2007; Yineger and Yewhalaw, 2007).

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There exists a deadlock in the system when there is a set of processes waiting for resources held by other processes in the same set [15].

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…note, our results indicate disrupted fiber integrity (FA decreases) and disrupted tissue microstructures (MD increases) in schizophrenia that concur with results of previous histopathologic studies where abnormalities in oligodendrocyte function have been reported [Uranova et al., 2001, 2004].

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…FAST2 o form an ARF (Chen et al., 1997; Labbé et al., 1998; Zhou et al., 1998) which acts as a transcriptional activator to regulate gene expression (Liu et al., 1997; Labbé et al., 1998; reviewed in Attisano and Wrana, 1998; Kretzschmar and Massagué, 1998; Heldin et al., 1997; Whitman, 1998).

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[19] System Task support, tools Older adults Location, activities Sensors, camera, GPS User-based, route, interface, content Concept

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In contrast, in newly formed CNV lesions, significant leakage may have been evident on angiography but minimal fluid may have accumulated within or below the retina as a result of compensatory removal of fluid by a still relatively functional RPE [14].

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We then apply PVI to three probabilistic models: the Dirichlet process mixture model (DPMM; Antoniak, 1974; Escobar and West, 1995; Fearnhead, 2004), the infinite HMM (iHMM; Beal et al., 2002; Teh et al., 2006), and the Ising model.

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Most animal and plant D-type cyclins have the amino acid motif LxCxE near their amino terminus which is required for binding to the RBR protein (Ewen et al. 1993; Soni et al. 1995; Menges et al. 2007).

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Another population of Astyanax eigenmanniorum, from Caetano stream, Uberlandia/MG, analyzed by Torres-Mariano and Morelli (2008), showed a formula of 14m + 18sm + 10st + 6a, constituted by a greater number of meta- and submetacentric chromosomes (32), compared with the results obtained in this…

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Existing complexity measures for concurrent algorithms typically consider the worst case [1, 3], and in rare instances the best case [4, 10], when estimating the number of steps required for an operation executed by a process to terminate.

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Identity begins to take shape during adolescence, but, with the incorporation of new life experiences, is continually modified throughout adulthood (McLean, 2008). Theories of identity maintain that individuals engage in particular actions to confirm their own identities and that social role expectations are internalized and demonstrated through behavior (Stryker & Burke, 2000). Most historical models of adult development that are discussed in the literature are based on research with all-male subjects or were written from a male vantage point (Caffarella & Olson, 1993). Factors that most meaningfully impact the identities of older women are unacknowledged in these models (Price, 1998). Such models, including work by Erikson (1982), stress D ow nl oa de d by [ M cG ill U ni ve rs ity L ib ra ry ] at 2 0: 35 0 5 Fe br ua ry 2 01 5

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…high mean concentration of Fe in leafy green plants was lower than the concentrations (140, 292.35 and 601.9 mg/kg) obtained by Brar et al. (2000) in India; Yadav et al. (2013) in India; and Al-Jaboobi et al. (2014) in Morocco for leafy green plants irrigated with groundwater, respectively.

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The present experiment also calculated sensitivity by using the modified Davison and Tustin (1978) equations proposed by Lie and Alsop (2007; 2009).

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Fish abundance at each site was estimated using multiple-pass depletion methods (Hayes et al. 2007), val-

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However, the scores from the max may be incomparable, and are often calibrated on a validation set to increase performance (Platt, 1999; Lin et al, 2007).

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As in our recent works [24, 29, 31], we consider the following potential [44, 45] with a Cα chain representation and favorable pairwise native-centric interactions:

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Background It is estimated that, at the time of diagnosis of type 2 diabetes mellitus, more than 10 % of patients have one or two risk factors for foot disease, such as peripheral neuropathy (PN) or peripheral vascular disease (PVD) [1].

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Ten years after the relevant work of Kozlowski et al., young post-communist democracies would appear to be incapable of defying this deeply rooted scientific/technical model. In a much more recent study, Vinkler (1998) encounters similar conducts in a comparison of Western Europe, the USA and Japan, with the scientific situation of countries from Central and Eastern Europe (excepting the former USSR).

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Genes coding for proteins with the GG(D/E)EF and E(A/V)L sequence motifs were identified with PSI-BLAST [38] using reference sequences available at NCBI Gene Entrez [39] [See Additional file 1], against the three K. pneumoniae genomes.

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This indicates that instabilities similar to those observed in the maize MuDR sequence (Hershberger et al. 1991) do not occur in the case of the rice OsMu element.

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Table 2: Per-class and average F1 scores (in %) of the models on the KITTI dataset (Ros et al. 2015; Kundu et al. 2014)

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Oxidative stress present in insulin resistant obese subjects may worsen the angiotoxicity of homocysteine thus increasing the risk of arteriosclerosis [8, 9].

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from the local row bu er (read or write), and iii) clearing the local row bu er (precharging) [14, 37, 38, 66, 76, 77, 78].

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D and 3-CB has been confirmed (Kasberg et al., 1995; Laemmli et al., 2000, 2004; Pérez-Pantoja et al., 2000; Plumeier et al., 2002).

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Since 2000, arctic ground squirrel populations in the boreal forest have remained low and in some locations have been extirpated (Gillis et al. 2005; Donker and Krebs 2011).

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The first-round PCR products were used directly in a second round of PCR using primers 2B and F (Hatada et al., 2010; Shibata et al., 2007; Yoshimura et al., 2006, 2010b) for gp120, IN 2F (59-CTGGCATGGGTACCAGCACACAA-39) and IN 2R (39-CCTAGTGGGATGTGTACTTCTGAACTTA-39) for IN, and IN 2F and F for…

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This explanation is consistent with the observation that Swiss mice were unable to respond to surgical removal of some of their mammary tissue by elevation of milk production in the remaining tissue (Hammond et al., 1996) which is also consistent with the peripheral limitation hypothesis.

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A method based on optimizing the training data likelihood, such as Morfessor (Creutz and Lagus, 2002; Creutz and Lagus, 2007; Virpioja et al., 2013), ensures that common phenomena are modeled more accurately, for example by using full forms for highly-frequent words even if they consist of multiple morphemes.

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Poincaré plots were constructed from the R–R interval data for each participant (Carrasco et al. 2001).

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in the contractile apparatus and the receptors, extracellular matrix protein deposition, and fibrosis in the smooth muscle cells [6–8].

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responsible on their own, and consider policy intervention a more effective solution (Chatterji and Listokin, 2007; Fleming and Jones, 2013; Karnani, 2007).

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[17] and earlier studies, that there is indeed an active (transcellular) component to oxalate absorption in the large intestine and this is represented by DRA.

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Unfortunately slight misinferences in the orientation of SNPs would artificially increase the amount of high frequency derived alleles (Williamson et al., 2005; Eyre-Walker et al., 2006).

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Glucose uptake was assessed in intact soleus muscle, a small thin slow-twitch muscle, incubated without or with insulin (60 nmol/l) as described previously [22].

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Furthermore, microsatellite instable (MSI) colorectal cancers generally have a better prognosis and relatively rarely metastasize, yet around 5% of metastatic colorectal cancers are MSI (12).

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We compare the proposed classification algorithm (denoted as ‚ÄúCoLiBRi‚Äù for ‚ÄúConcept Lattice-Based Rule-learner‚Äù) with Scikit-learn [12] implementations of CART [2], Random Forest [1] and kNN on several datasets from the UCI machine learning repository.1
 1 http://repository.seasr.org/Datasets/UCI/csv/
 We used Gini impurity as a criterion for rule selection and MDL [3] for continuous feature discretization.

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We therefore contrast our work with state-of-the-art MI optimization algorithms included in the previously mentioned General Algebraic Modeling System (GAMS) (Bussieck and Meeraus, 2004) commercial algorithm suite as well as the Mixed-Integer Evolution Strategy (MIES) (Li et al., 2013).

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The general conclusions have been that a bead beating step is needed, and the FastDNA spin kit for soil has been recommended due to general high yield and purity [10,12].

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This may be due to the role of lysosomes in parvovirus-induced cell death, since the NAD /NADH system is involved in electron transport and acidification in these organelles (9).

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The resected specimens were classified as either low-grade mucinous carcinoma peritonei or high-grade mucinous carcinoma peritonei on pathologic evaluation by experienced peritoneal malignancy pathologist.(8) Postoperative complications were classified according to the Clavien– Dindo classification.

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On the one hand, our findings are consistent with results from experimental animal studies that described environmental effects of early life stress on inflammation levels (Cole et al., 2012, Delpech et al., 2016).

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We measured the diameters of
terminal portion of the ICA; C7 segment (origin from posterior communicating artery to the bifurcation of the ICA) [31] on source image of TOF MRA.

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Antibodies recognizing mammalian homologs of katanin also recognize large microtubule-dependent structures surrounding γ-tubulin foci at spindle poles in several cell types and, in addition, recognize a smaller microtubule-independent focus at the centrosome in some cell types (McNally and Thomas, 1998).

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Although Hh signaling by SMOH was reported to be required in a chronic myeloid leukemia-like disease (Dierks et al., 2008; Zhao et al., 2009), it was found to be dispensable for the development of acute leukemias induced by either the Received 3 November 2009; revised 20 April 2010; accepted 20 May 2010; published online 5 July 2010 Correspondence: Dr TN Hartmann or Professor R Greil, Laboratory for Immunological and Molecular Cancer Research, IIIrd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Paracelsus Medical University, Salzburg 5020, Austria.

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Reported t-statistics are based on robust standard errors estimated using the Huber (1967) – White (1980) procedure.

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…plasticity deficits in hMT mice HFS of glutamatergic afferents led to the induction of robust LTD
in MSNs in both coronal and parasagittal slices from NT mice,
similar in magnitude and duration to that reported previously in mouse brain slices (Goldberg et al., 2005; Bonsi et al., 2008)
(Fig.

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On the other hand, negative regulation of flavonoidspecific genes by R2R3-MYB or R3-MYB proteins have also been reported in some species (Aharoni et al. 2001; Paolocci et al. 2011; Dubos et al. 2008; Matsui et al. 2008).

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, 2002) and whose uptake is involved in the long-lasting enhancement of synaptic transmission and may therefore affect synaptic plasticity (Sergeeva et al., 2003).

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In this paper, AAUC is computed over the first 15 recall points:
 AAUC = 1
 15 ¬∑ 15‚àë i=1 Precision(i).

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Relationship satisfaction was assessed using Funk and Rogge‚Äôs (2007) four-item measure of relationship satisfaction. These items measured satisfaction with the participant‚Äôs romantic partner (e.g., ‚ÄúHow rewarding is your relationship with your partner?‚Äù and ‚ÄúI have a warm and comfortable relationship with my partner‚Äù). The items were summed to create an index of relationship satisfaction (Œ± = .92). Communal strengths were measured using a 10-item measure developed by Mills, Clark, Ford, and Johnson (2004). The Œ± for the current sample was .

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Rabbits were divided into three groups: group 1 (sham), animals were anesthetized for 40 min, but no other intervention was performed prior to blood-draw; group 2 (rIPC), remote ischemic preconditioning was induced through four cycles of 5 min of hindlimb ischemia (via a tourniquet), followed by 5 min of reperfusion as previously described [2]; and group 3, electroacupuncture (EA) was applied bilaterally with one needle at the P6 Neiguan point (located on the medial forelimb 1/6 the length of the line from the wrist to the elbow between the radius and ulna) and the other needle at P5 (Jianshi point).

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…or undermine the autoimmunity hypothesis (Kierszenbaum 1986, 1999, 2003, 2005; Eisen and Kahn 1991; Avila 1992; Fernandez et al. 1992; Kalil and CunhaNeto 1996; Brener and Gazzinelli 1997; Andrade 1999; Soares et al. 2001; Leon and Engman 2001, 2002; Gironés and Fresno 2003; Gironés et al. 2005).

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For the CIFAR-10 dataset, the DNN architecture adopted by Carlini and Wagner is not state-of-the-art. erefore, we do not adopt their DNN architecture for the CIFAR-10 dataset.

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identified in the literature for nano-foods from a survey with a convenience sample in Switzerland (Siegrist et al. 2007).

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These include issues such as the internalisation and pricing of knowledge assets (Markusen, 1984; 2002), the advantages of horizontal (Horstmann and Markusen, 1992; Markusen and Venables, 2000) and vertical integration (Aghion and Tirole, 1997; Grossman and Hart, 1986), and the advantages of subcontracting and licensing versus FDI (Ethier and Markusen, 1996; Helpman and Grossman, 2002; Horstmann and Markusen, 1987; Markusen, 2002).

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Horizontal CSTN and transverse spinal cord slices (L4-L6) from 2 to 4 weeks old rats were prepared using methods similar those previously described [52].

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To determine the significance of the change from baseline of each lipid species, subclass, and class during the postprandial period (for dairy or soy meals) we performed the nonparametric Friedman test on the plasma concentration values and corrected for multiple comparisons by using the Benjamini-Hochberg method (23).

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section 3, excels for different types of applications and network constraints as discussed in [3], [23], [21], [22].

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tumor progression in non-muscle-invasive bladder cancer (NMIBC) patients treated with intravesical Bacillus Calmette-Guérin (BCG) [10].

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These different estimates were mostly smaller than those reported by Trail et al. (1991b) in a governmental ranch of N Dama cattle in Gabon (PCV heritabilities at 0.64).

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Huett et al. (2005) compared nitrogen and phosphorus removal from plant nursery runoff in vegetated SSF CWs and unvegetated filters in Australia, and reported that removal efficiency for planted wetlands increased from 63.4 and 69.1% for TN and NO3–

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, 2009), particularly at altitudes less than 2 km, but found the overprediction to correlate with HCHO concentrations, indicating missing reactive VOCs in the model (Mao et al., 2009).

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A decrease in stocking rate would result in further improvements in ecological integrity (Jansen et al. 1999; Fondell and Ball 2004; Martin and Possingham 2005; Dennis et al. 2008; Powell 2008; Little et al. 2013).

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, 2002), the relationship between upslope pore pressure dynamics and hillslope discharge (Uchida et al., 2004) or event water ratio (e.

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Comparisons in inclusion criteria, screening parameters, and results of LDCT screening for lung cancer are summarized in Table 3 (22-26).

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The changes in glucose uptake in muscle and adipose cells overexpressing PED are accompanied by inhibition of insulin-dependent translocation of GLUT4, the major insulin-responsive glucose transporter (1).

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western blots were developed with Odyssey CLx Infrared Imaging Systems (LI-COR, USA) [42, 60, 61].

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Animals, chemicals, and antibodies All animals and chemicals used were previously described in Omezzine et al. (2003) and Bozec et al.

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The age of giant nupDNA fragment A was calculated by dividing the corrected K value of type 2 substitutions (see Results) by the absolute substitution rate of the synonymous sites in the nuclear genes of rice (Ramakrishna et al., 2002).

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Sarriot et al. (2004a) recommend moving assessment of organizational viability beyond its financial dimension.

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Constant comparison is a data analysis strategy that involves moving back and forth between the data and the scene of study comparing incident to incident until categories emerge (Beck, 2004).

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Renin inhibitors bind to the active site of renin and inhibit its binding to angiotensinogen, which is the rate‐determining step of the RAS cascade and, consequently, prevents the formation of Ang I and Ang II (36).

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Regarding camera sensors, the work of Jung et al (2014) explores information from a depthcamera, while a monocular camera is employed in (Wu et al 2009; Costante et al 2013), and an omnidirectional one in (Ullah et al 2008; Yuan et al 2011).

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This session also helps to decrease the number of trials in the formal TMS sessions since the critical SSD does not then have to be obtained during the TMS trials and there is then a better chance to observe the effects of TMS (see also Chambers et al., 2007).

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Specifically, the autonomous vehicle segmentation dataset KITTI (Ros et al. 2015) is used, augmented with 49 additional train images by (Kundu et al.

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For the wild-type receptor, the P119L mutant, the F122G mutant, and the T197A mutant, stably transfected cell lines were selected and assessed, as previously described (3).

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Enzymatic activity of purified NS2B(H)-NS3pro was assayed against commercially available synthetic peptide substrates containing either three non-prime side residues, Boc-GRR-amc and Boc-LRR-amc; four residues, Ac-nKRR-amc, Ac-nKRR-amc; and five residues, Pyr-RTKR-amc, and a previously described internally quenched DEN NS3 substrate, Abz-(R)4SAGnY-amide [22] (all purchased from Peptides International, KY, USA).

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Differences between central (aortic) and brachial BP could be clinically important, as central BP is more closely correlated with target organ damage in hypertension [4]; is differentially influenced by antihypertensive therapy compared with brachial BP [5]; and may be a superior predictor of cardiovascular events than brachial BP [6].

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The results obtained in our study agree with previous clinical observations that have failed to detect a link between administration of exogenous glutamate and clinical neurological injury in association with cardiac surgery.(11,12) The results also argue against a role for exogenous glutamate in the evolution of subclinical neurological injury.

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…and Kockelkorn, 2006a, Damala and Kockelkorn, 2006b, Damala,
2007a, Damala, 2007b, Oppermann and Sprecht, 1998, Santoro et al., 2007) and “nomadic
devices” (Brelot et al., 2005, Damala et al., 2005, Hsi, 2004, Vlahakis et al., 2005) are other
variations often enough used in the relevant literature.

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…genetic variation, but the disease phenotype does not only result from functional alteration of the affected gene product, perturbations rather spread along the links of the underpinning cellular networks (Schadt 2009; Barabási et al 2011; Menche et al 2015; Piñero et al 2016; Caldera et al 2017).

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[37] Scores were described continuously from 0 to 27 to measure depression severity and also classified dichotomously as major depression (score .

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Bork et al. (2010) reported that highly significant differences in methylation patterns were observed at specific CpG sites, such as those near homeobox genes between early and late cultures.

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instance, are also important barriers to this activity (Davison et al., 2008).

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For example, in Table 2 BCR dataset is cross validated with
three feature sets obtained from Lancet, CCR and 70-gene signature.

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…to a single transcript (e.g., reads originating from constitutive exons) or even to unique genomic locations, transcript- and gene-expression levels can only be estimated with some degree of certainty, that is, with estimation error (Jiang and Wong, 2009; Turro et al., 2011; Trapnell et al., 2013).

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5 mm,[6,13] absence of communications of both SIEVs crossing the abdominal midline,[6,13] absence of direct communications by perforators between the SIEV and the deep inferior epigastric vein (DIEV),[6] number of perforators of the flap,[5] and subcutaneous tissue thickness.

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We confirmed the data of others that proliferating basal cells appear in patches or clusters (Moulton et al., 1970; Graziadei and Monti Graziadei, 1979; Monti Graziadei and Graziadei, 1979; Suzuki and Takeda, 1993; Huard and Schwob, 1995).

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We do not conclude from our results that neither factor ever plays a role; after all, the possible effects of both had been demonstrated previously (Seeley, 1986; Seeley and Tovey, 1994).

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Moreover, the value of t1/2 after i.v. administration of MBF was similar (13.78 h) to a previous report (Yohannes et al., 2015).

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After testis irradiation, hypomethylation of retrotransposed interspersed repeat elements (LINEs and SINEs) was found in the offspring (Filkowski et al., 2010) next to lower levels of the methylated CpG binding protein MeCP2 and the DNA homologous recombination
Assisted reproduction and epigenetic…

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heterozygote advantage due to heterotic selection (Clegg, 1980; Rüter et al., 2000).

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modeled in terms of CA, including the Belousov–Zhabotinsky (BZ) reaction [1,2], the Turing system [3], a precipitating BZ system for computation of Voronoi diagram [4,5], and

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A retrospective cohort study abstracted medical records of 45,308 Medicare beneficiaries with AMI.(87) Of these, 7.

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GC content for each gene was obtained from the Conditional Quantile Normalization R package for 15 277 genes (17).

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It has been previously reported that the blockage of the replication machinery can lead to uncoupling of leading and lagging strand synthesis, resulting in the generation of ssDNA, which in turn will be occupied by RPA, an SSB (38, 39).

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The methodology is primarily influenced by the Grounded Theory approach, which has been used successfully in previous studies (Jones, 2004; Orlikowski & Iacono, 2001).

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Deficits were more pronounced in the right than in the left hemisphere (Ballmaier et al, 2004c), implying a possible involvement of abnormalities in inter-hemispheric information transfer in late-onset depression (Kumar et al, 2000).

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Based on the new results and previous findings (12, 21, 22), we propose a functional model for CmeR in which it binds to target DNA via its N-terminal HTH motif and interacts with various inducing signals via its large ligand-binding pocket located in the Cterminal region.

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In trials with zebra ®nches, the numbers of sperm collected using false cloacas (Pellatt and Birkhead 1994) are similar to those produced by natural copulations determined by comparing the number of sperm in the seminal glomera of males that had or had not recently copulated (Birkhead et al. 1993).

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These studies showed that expression of miR-99a could reduce the expression of a number of proto-oncogenes by targeting their 3′ untranslated region (3′UTR) [8-13].

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Bacterial strains, plasmids, and media
Escherichia coli JM109 (Yanisch-Perron et al. 1985) and pGEM-T Easy (Promega, Madison, USA) were used in routine gene manipulation.

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…proteins initially has been demonstrated in tissue culture model systems of adipogenesis and hematopoiesis (Lin and Lane 1992; Freytag et al. 1994; Hu et al. 1995; Müller et al. 1995; Nerlov et al. 1998) and has now been firmly established through analysis of the respective knockout mice…

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The 2 cycles/letter formula [16,17] suggests that the most important spatial frequency content of these letters is :2.

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At present, pulmonary fibrosis model can be constructed by several methods, including paraquat and amiodarone [21, 22].

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org variability in parasites (Pieniazek et al. 1999; Chicharro, Jimenez and Alvar, 2003; Pratlong et al. 2003).

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brood size), while males tend to increase their amount of care with increasing work load (Santos and Nakagawa 2012).

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How ever, in recent years, X linked genes have been shown to be expressed in both parental chromosomes in the human placenta (Moreira de Mello et al., 2010).

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Therefore, the risk of selection bias and confounding is greater than in a review of RCTs [58].

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The large majority of T6SS genes (12 out of 17), including VipA, VipB, ClpV, VasF and VasK, are required for Hcp secretion, killing of amoeba and bacteria and are predicted to encode structural T6SS components [9,12,20].

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However, the clinical value of CA125 as a marker of ovarian cancer is low, due to its expression in non-malignant or non-ovarian malignant conditions (Tuxen et al, 1995; Meyer and Rustin, 2000).

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The quality of physician–patient communication has been associated with patient adherence to treatment (Zolnierek & Dimatteo, 2009), uptake of cancer screening (Carcaise-Edinboro & Bradley, 2008), improved blood pressure control in hypertensive patients (Orth, Stiles, Scherwitz, Hennrikus, & Vallbona, 1987), and reductions in the risk of serious medical error (Kuzel et al., 2004).

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ly), which have been originally identified as molecules activated by growth factor-stimulation of fibroblusts, are key kinases in the intracellular signal transduction pathways (1-6).

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Bacterial strains and growth conditions Listeria monocytogenes EGDe was used for all experiments except for the D-alanine auxotrophy experiments, which were performed with L.monocytogenes strain DP-L3506 [23].

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These finding are consistent with the findings of other studies of Hispanic mothers [12,13,23] and parents [26].

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Partial or complete deletion of CS2, as in the case of ABF1 (1-643) and (1-638), doubled the plasmid loss rate of pARS1 (compare column 1 with columns 5 and 7 in Fig.

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The hypothesis that GBI scores differ from 0 (with 0 meaning no effect of the operation on HRQOL) was tested by the t test for independent samples (> = 0.05).

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…proteins like PLA2, three-finger toxins, etc. have evolved via mutations targeted around their functional domains while the structural residues are constrained and maintain a highly conserved scaffold (Mackessy 2002; Kini 2004; Fry et al. 2006, 2008; Yamazaki and Morita 2007; Doley et al. 2008).

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The upregulated PDHC expression level upon ND was in line with the previous findings that upregulation of PDHCmediated acetylCoA synthesis contributed to the augmented TAG accumulation (Li et al. 2014b; Jia et al. 2015).

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…into 34 different gyral regions per hemisphere, for each of which a mean cortical thickness value was calculated (Desikan et al. 2006; Fischl et al. 2004b) Automated Freesurfer subcortical parcellation was employed to extract volumes for the amygdala, hippocampus, whole brain grey…

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[14] collected misinformation automatically in order to prevent false information from spreading through social media.

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In one recent study using the tractography applying constrained spherical deconvolution to investigate a total of 43 patients
with ADHD, Silk et al. (2016) found a significant lateralization to the left for fractional anisotropy (FA, a DTI measurement) in the putamen tracts.

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loss was tested in the context of overexpression of the oncogene NRAS and a short hairpin against p53, because ATRX mutation by itself is not associated with cancer development in humans (12), and glial tumors with ATRX mutations almost always include TP53 mutations (1).

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, 2012), and other studies have indicated that the fornix is affected in Pick’s disease, FTD with tau mutation, or TAR-DNA-binding protein43 type C pathology, but not for FTD caused by a progranulin mutation or with fused-in-sarcoma protein accumulation (Rohrer et al., 2011; Hornberger et al., 2012).

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Therefore, the relay layout is of great importance in the cooperative wireless-powered systems [16, 25].

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Furthermore, the quality of RNA may vary significantly with each extraction and during experimentation resulting in a constant requirement for monitoring of RNA quality (Schroeder et al. 2006).

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Other studies suggest that altering affinity to FcRn might alter the bioavailability of mAbs (Deng et al., 2010; Deng et al., 2012), and SC bioavailability appears lower in FcRn-deficient mice as compared to wild type animals (Wang et al.

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Also, HA can interact with various cellular receptors, including CD44, RHAMM, and LYVE-1, to promote angiogenesis [6], as well as the growth, invasion and metastasis of tumors [7-9].

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Electrophoretic mobility shift assays (EMSAs) were performed as previously described (8, 10, 22, 39).

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The use of GDNF and GFRa1 to trigger RET downstream pathways is in accordance with other previously published reports [36,48] and also relies on the fact that GDNF is the strongest activator of RET signaling in enteric glial cells upon a number of physiological and pathological events[55].

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These observations are in agreement with the studies of pcy mice model by Okada et al, showing that both cystic epithelial cells and interstitial fibroblasts express higher levels of collagens compared to normal controls [10].

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This finding is similar to those reported in colonization screening by other authors [20].

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Sensitivity analysis revealed that 11 independent studies were the main source of heterogeneity[21,26–29,31–36].

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FGF23 Activates FGFR4 and PLCg Signaling in the Absence of a-Klotho To study FGF-FGFR-dependent signaling, we used HEK293 cells that express all FGFR isoforms but lack a-klotho (data not shown), similar to cardiac myocytes (Faul et al., 2011).

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Despite the lower number of patches utilized, this study will use slightly larger sample sizes of dispersed seedlings than Grivet et al. (2009), incorporating subsequent improvements in genotypic assignment (Smouse et al. 2012).

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The design framework of nonlinear single-rate sampled-data systems has been given and several design methods of stabilizing controllers have been discussed ([4], [8], [9], [10], [11]).

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40-Hz band of the R-wave‚ÄìRwave-interbeat interval series using CMet cardiac metric software (Allen et al., 2007).

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Support vector machines, developed by Vapnic, are based on the statistical learning theory [8] and recognized as an efficient and powerful regression and time series prediction technique.

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[1] reported net cumulative discontinuation rates for bleeding problems of 6 per 100 women during the first year of contraceptive use, increasing to 10 per 100 women during the third year.

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Total RNAs for cDNA synthesis were isolated using a combination of CTAB extraction and the RNeasy Plant Mini kit (Qiagen Valencia, CA USA) as previously described for basal angiosperms [11].

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Given the more superior position of foramen cecum relative to nasion, the equivalent basion-sella-nasion angle would actually be even lower, placing LB1 ~3 SD below the average DS value reported in [58].

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Thus, the Andean uplift greatly influenced biodiversity organization in South America (Gentry 1982; Hoorn et al. 1995, 2010; Jørgensen & Le onY anez 1999; Antonelli et al. 2010).

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Earlier works have evaluated these measures for other tasks such as influence maximization [13], or selecting gatekeeper nodes [15].

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…the roughly 4-fold enhanced DNA methyltransferase activity conferred by Dnmt3amERe, which is reminiscent of the finding that the methylation-status of the vast majority of CpG islands in SV40-transformed human fibroblasts was unaffected despite 50-fold overexpression of Dnmt1 (Feltus et al. 2003).

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Using the algorithms from Schneider (2016, 2014) or from Section 6 (or enhanced telescoping algorithms from Schneider, 2005a, 2008, 2010c, 2015) we can now compute a basis of V (( f1, . . . , fd), E), and can decide if there exists a g ∈ E and (c1, . . . , cd) ∈Kd \ {0} such that (6.2) holds.

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Hendricks et al. had suggested that “topic shift crucially requires speakers to take into account the listener’s perspective” (p. 395, Hendriks et al., 2014), which would result in the use of definite NPs.

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These results, together with previous findings [49], indicate that adiponectin and its receptors, especially ADIPOR2, play an important role in regulating fasting plasma triglyceride levels, and that they could have a potential role in VLDL metabolism.

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Recently, a novel method called minimal distance maximization (MDM) [12,13] was developed which does not require any weighting function.

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The third category of techniques uses local spatio-temporal features [16, 27, 14, 8, 22] which have recently become a very popular video representation method for action recognition.

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The searching ranges for k and m are as follows: k 2 [1,100] and m 2 [1,10] for the Wieslaw dataset, k 2 [1,100] and m 2 [1,100] for the Australian dataset.

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The E5 protein potentiates viral gene expression and enhances the malignant transformation properties of E6 and E7, which are major transforming proteins of HPV infected cells [3–8].

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Additional support for Öhman’s view comes from electromyographic and neuroimaging studies of unconscious processing of masked facial expressions (Morris et al., 1998; Whalen et al., 1998; Dimberg, 2000; Dimberg et al., 2000).

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Despite the very high human density at its eastern edge, the forest is inside the UMNP and is generally well protected (Rovero et al. 2012); 2) Uzungwa Scarp Forest Reserve (US, 314 km) which also covers the steep, east-facing escarpment rising from the Kilombero Valley, and is characterized by continuous cover from lowland, deciduous forest to evergreen moist montane forest.

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…important role of intragenic and possibly intergenic recombination for the origin of MHC sequence polymorphism is accumulating from population sequence data (Langefors et al. 2001b; Richman et al. 2001, 2003), supporting direct experimental observation using sperm typing (Högstrand and Böhme 1994).

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