However, how frataxin interacts with the Fe-S cluster biosynthesis components remains unclear as direct one-to-one interactions with each component were reported (IscS [12,22], IscU/Isu1 [6,11,16] or ISD11/Isd11 [14,15]).

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In the study by Hickey et al. (2012), spikes were sampled from the field at the point of physiological
robinson et al.: genomic regions influencing root traits in barley 11 of 13
maturity, dried, grain threshed by hand, and stored at −20C to preserve grain dormancy before germination testing.

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The drug also reduces catecholamine secretion, thereby reducing stress and leading to a modest (10-20%) reduction in heart rate and blood pressure, which may be particularly beneficial in patients with cardiovascular disease.(7) Unlike midazolam, dexmedetomidine does not affect the ventilatory response to carbon dioxide.

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By clustering with lowly aggressive close kin (King 1989a,b; Viblanc et al. 2010; Arnaud, Dobson & Murie 2012), breeding females may decrease the time/energy cost of maintaining territorial boundaries (Festa-Bianchet & Boag 1982; Murie & Harris 1988), which could ultimately lead to increases in net energy income (TA) or higher allocations in somatic or reproductive functions.

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Ophthalmic symptoms are rare manifestations of the intracranial arachnoid cyst, and include unilateral exophthalmos, visual field abnormality, decreased visual acuity and isolated palsies of the third, fourth and sixth cranial nerves [1–5].

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Recent studies identified Wee1 as a potential molecular target in cancer cells and the selective small molecule Wee1-inhibitor MK-1775 demonstrated promising results in cancer cells with enhanced levels of Wee1 (96-98).

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These problems combine to make early diagnosis essential and immediate treatment a necessity, even for the youngest patients [17, 18].

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Also, results demonstrated that the molecular weight and G/M ratio were important factors in controlling the antioxidant properties of sodium alginate (Şen 2011).

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Recently, the light-induced method, which is based on the changes of surface wettability of certain materials [12], has been developed and provides amore convenient approach for cell harvesting [13].

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Currently, with advances in radiotherapeutic, chemotherapeutic, and surgical techniques, limb-salvage surgery has become an accepted treatment [2–9].

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…lifetimes, whereas indirect benefits refer to benefits to genetically related recipients; i.e., benefits that increase the inclusive fitness of benefactors but typicaly imply fitness costs that are not compensated during the benefactors’ lifetimes (Hamilton 1964; Trivers 1971; West et al. 2007).

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DOI: 10.7554/eLife.08828 1 of 27
mitochondrial division (Friedman et al., 2011; Korobova et al., 2013; Murley et al., 2013; Korobova et al., 2014).

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The remnant of the total plasma membranes after extraction of caveolae is called bulk plasma membranes (40) (Fig.

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We used an active contour algorithm [10] to segment the organs from 340 coronal slices over the two patients.

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For women with competing care-giving responsibilities, this involves allowing them to be accompanied by their children, providing on-site childcare or offering childcare subsidies [64,68,79].

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This change accelerates mitochondrial electron transport in the respiratory chain and produces more influx of electrons to the mitochondrial matrix, which in turn produces more ROS and RNS [21, 23, 33, 64, 100, 101, 107–118].

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Nevertheless, there is no high-quality evidence for the effectiveness of manipulative therapy for the treatment of CR.([8,17,18]) Shi-style cervical manipulation (SCM) is commonly used to treat CR in China.

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Consistent with previous reports (al-Khodairy et al., 1995; Seufert et al., 1995; Tanaka et al., 1999; Biggins et al., 2001), our data showed that Smt3 and Ubc9 have pivotal functions during mitosis.

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Scp160p has already been implicated in one such network, the SESA (SMY2/EAP1/SCP160/ASC1) network, in the function of a translational activator (11,25).

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Clinical reports of energetic stress in HCM hearts (14, 15) prompted us to measure mitochondrial respiration, mitochondrial copy number, ROS emission/scavenging, and calcium handling in these 2 HCM mouse models.

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Previous empirical analyses of subnational consumer subsidies found that a majority of solar adoption was attributable to subsidies (e.g., Hughes and Podolefsky, 2015; Burr, 2016; De Groote and Verboven, 2016; Gillingham and Tsvetanov, 2017).

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The third group of proteins might be necessary to cope with the alterations in electron Xow such as NdhD2, OCP, and the thioredoxin-like AhpC (Ohkawa et al. 2000; Kobayashi et al. 2004; Wilson et al. 2006).

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These results are consistent with field observations of plasma electrolyte concentrations and thermal behaviour of the lizards Sauromalus hispidus and Uromastix acanthinurus (Grenot 1976; Smits 1984) and laboratory observations of S. hispidus (Smits et al. 1986).

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4 lead to a decrease in SC absorption in mice (Deng et al., 2010; Deng et al., 2012).

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found that SNPs of MMP-1 were linked to an increased risk of colorectal cancer [12,13].

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Matricellular proteins are thought to contribute to the organization and biomechanical stability of
the ECM by modulating cell-matrix interactions and cell signaling rather than by serving directly as structural components (Bornstein et al., 2000).

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The beneficial role of PBM as supportive modality in the management of postmastectomy lymphedema is well established based on strong evidence [15, 16] and recent data suggest its beneficial role concerning radiation-induced oral mucositis [17–20].

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The mitochondrial transmembrane potential was measured using flow cytometry of cells stained with 5,5′,6,6′- tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanineiodide (JC-1) (Cossarizza et al., 1993) as described previously (Dymkowska et al., 2006).

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The language models were characterN-grams trained using texts from the Corpus of Spontaneous Japanese (CSJ) [23], which contains 12.

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Cisplatin has dramatically been used as the first line treatment for several types of solid tumors, such as breast, head and neck, ovarian, and lung cancers [17].

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In recent years, a similar genotype shift has been observed in South Korea, northern Vietnam, China, Taiwan and Thailand (Chen et al., 2011; Nam et al., 1996; Nga et al., 2004; Nitatpattana et al., 2008; Pan et al., 2011; Wang et al., 2007; Yang et al., 2004; Yun et al., 2010; Zhang et al., 2009, 2011).

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However, localization of additional γ-tubulin that surrounds the centrosomes only during mitosis does require microtubules (McNally and Thomas, 1998; Khodjakov and Rieder, 1999).

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…is consistent with the currently-held notion that dsRNA targets the gene-specific destruction of mRNA in a wide variety of eukaryotic cells (Fire et al., 1998; Tabara et al., 1998; Tabara et al., 1999; Sanchez-Alvorado and Newmark, 1999; Grishok et al., 2000; Boscher and Labouesse, 2000;…

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Spermatogonial transplantation was performed and recipients were prepared as described previously [7].

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More examples of contradictory results have been observed in bovines; some reports (Zakhartchenko et al., 2001; Bhuiyan et al., 2004) indicated a significant decrease in blastocyst

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Increasing the number of EPIYA motifs leads to an increase in the level of CagA phosphorylation (Higashi et al., 2002a; Argent et al., 2004, 2008a; Zhang et al., 2005; Naito et al., 2006).

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, 2008), and Srebp1/2 are known to interact with Hmgb1/2; their activity has been reported to be enhanced by Hmgb1 (Najima et al., 2005).

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This is in keeping with the report of Blickstein et al,[3,15] which showed that the higher the combined twin birthweight the less likely it was to deliver discordant pairs.

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Coinciding with our results, it has been previously reported that i.p. injections of β-glucan reduced IFN-γ production induced by concanavalin A in mice (Pelizon et al., 2003).

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The occurrence of soft tissue tumors in such field of low-dose irradiation (LDRI) has also been emphasized by other authors [50, 52, 53] reporting the development of tumors of the skull bone and neck after exposure to full-mouth diagnostic dental X-ray film [3] and to irradiation for enlarged tonsils [54] and thymus [55].

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In this chapter we will present the formalism for these different kinds of beamformers in their scalar form, then develop the formalism for a vector beamformer (Sekihara et al., 2001, Quraan and Cheyne 2010) and an eigenstate-projected vector beamformer (Sekihara et al., 2001).

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, 2010), and retromer tubule formation is reported to be maximal at the time of Rab5-to-Rab7 conversion (Cullen and Korswagen, 2012; van Weering et al., 2012).

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A serotype-shift occurred over the years with a predominance of DENV-1in 2010, DENV-2 in 2013 and again DENV-1 in 2016 [25].

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Existing applications of neural meanfield models to anesthesiainduced changes in spontaneous EEG rhythmsmostly focused on understanding the dynamical mechanisms underlying bi-phasic responses (Bojak and Liley, 2005; Hutt and Longtin, 2010; Steyn-Ross et al., 1999).

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In phytophagous arthropods, atranorin was reported to elicit a significant avoidance (Nimis and Skert 2006) or to reduce growth of insect larvae (Pöykkö et al. 2005; Slansky 1979) but no protective effect of atranorin was noticed in snails (Gauslaa 2005; Hesbacher et al. 1995).

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…has been undertaken at several locations including the Ganges delta of southern Bangladesh (Wang and Imhoff 1993), Everglades National Park (Simard et al. 2006), Madagascar (Pasqualini et al. 1999), Kakadu and Daintree National Parks in Australia, French Guiana and Malaysia (Lucas et al. 2007).

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In [3], the authors show the bandwidth towards the L0 scratchpad memory is around L0Y times larger than the minimal (where each pixel is transferred once from the L1 to the L0 scratchpad memory).

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…Takamori et al. (2001)
Endocrine cells, diencephalon (thalamus);
presynaptic
Brainstem catecholaminergic groups
Stornetta et al. (2002a, b); PVN (Herman et al. 2004); ME CRH cells, PP Wittmann et al. (2013)
Not Viable (die at birth)
Moechars et al. (2006), WallenMackenzie et al. (2006)
VGluT3…

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Following Carreras (2007) and Koo and Collins (2010), before training we transform the training set trees to be the best achievable within the model class (i.e., the closest projective tree or 1-Endpoint-Crossing tree).

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A series of genes (termed exo) involved in succinoglycan biosynthesis have been cloned and sequenced (10, 11, 12, 67, 68, 103, 113).

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The main distribution of 13-galactosidase-producing cells in tissues from the different lines is summarized in Table I in parallel with the evaluation of collagen VI expression products in control embryos at different locations (Marvulli et al., 1996).

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…a high overlap between PSD-95 and PLCb1 signals in the cerebral cortex, thus confirming a well defined subcellular location for PLCb1, which previously could be only demonstrated by Western blot analysis of subcellular fractions (Taguchi et al., 2007) or electron microscopy (Fukaya et al., 2008).

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Neurodevelopmental outcome was assessed at 24 months using the Revised Griffith‚Äôs scales of Mental Development [24].

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The antioxidant BHT accumulates predominantly in the lung and induces alveolar epithelial damage because of its action on AEC1 (21), which is followed by the proliferation of pulmonary parenchymal cells resembling human UIP (20,22).

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However, unlike Cochrane and Saa-Requejo (2000), the authors do not use a Sharpe ratio criterion to restrict the price interval for assets in incomplete markets, but a generalized version of the coherent risk measure first introduced by Artzner et al. (1999). Carr et al. (2001) argue that economic agents will not only invest in any arbitrage opportunity, but also invest in any acceptable opportunity.

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Stress and the subsequent activation of the HPA axis facilitate the acquisition of cocaine self-administration (Tidey and Miczek, 1997; Mantsch et al., 1998); manipulations of the HPA axis resulting in a reduction of function through pharmacological or surgical means can attenuate the acquisition…

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For example, elk may form smaller groups when exposed to wolf predation risk in relatively closed habitats (Creel & Winnie 2005), but form larger groups in open habitats where wolf densities are higher (Gower et al. 2009).

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…mechanisms of resistance to CDDP have been described, including reduced intracellular accumulation of CDDP; increased detoxification of CDDP by the thiols, glutathione and metallothionein; increased DNA-repair activity; and increased tolerance to DNA damage (Galluzzi et al. 2012; Kelland 2007).

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2000) and in skeletal muscle denervated by transection of the sciatic nerve (Baumeister et al. 1997; Tsukamoto et al. 2002).

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Other potentially carcinogenic effects of insulin resistance stem from abnormal levels of glucose and fatty acids, which include: altered intracellular signaling, chronic inflammation resulting from production of reactive oxygen species, and enhanced proliferation of transformed colonocytes due to increased energy supply [1].

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Recent studies have shown that the global flux distribution in oleaginous Chlorella protothecoides and Chlamydomonas reinhardtii remains stable under nitrogen limiting conditions and is controlled by the availability of carbon precursors (Xiong et al. 2010; Fan et al. 2012).

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…Lemos et al., 2015) at baseline, allowed for the division of the aMCI group according to an AD-alike pattern of impairment at baseline (Lemos et al., 2015), and was associated with the risk of conversion to AD in follow-up studies (Auriacombe et al., 2010; Petersen, 2007; Sarazin et al., 2010).

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While there have been remarkable developments in the last ten years [1–6], structuring large-scale visual data is still an active research area and any improvements would have wide applicability.

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…2010b), jasmonic acid (JA) (Truman et al., 2007), azeleic acid (AA) (Jung et al., 2009), a CDR1-derived peptide (Xia et al., 2004), plastid glycerolipids (Nandi et al., 2004; Chaturvedi et al., 2008), G3P (Chanda et al., 2011) and an abietane diterpenoid, dehydroabietinal (Chaturvedi et al., 2012).

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rural, we calculated the relative prevalence of a missing value by other demographic and fitness variables using logistic regression [49].

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Consequently, the findings of our study suggest that increased PWV noted in new onset diabetes after kidney transplantation [48,49] may already, at least in part, be present before the transplantation and a result of pre-diabetes or insulin resistance in the uraemic patients awaiting a kidney transplant.

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However, even when using adjusted relative risk estimates, PAF estimates can be biased if there are unaccounted confounding factors leadings to overestimation of PAF [51].

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Other mutations in the sgl locus were identi®ed as demonstrating a cuticle phenotype similar to that of wingless (wg) mutants (HaÈ cker et al. 1997; Haerry et al. 1997).

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In a follow-up study using a clinical sample (Amir et al. 2012), individuals with SAD similarly lacked a positive reaction time bias relative to controls without SAD but, interestingly, did not differ in their reaction time to endorse or reject negative interpretations of social sentences.

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The data on avian influenza outbreaks in Vietnam from 2003 through to 2006 was provided by the Epidemiology Unit of the Department of Animal Health, Ministry of Agriculture and Rural Development of Vietnam; the characteristics of this dataset are explained elsewhere [6].

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With regard to family fit, there is evidence that a minority of deaf couples would prefer to have deaf children and would consider using prenatal diagnosis to identify and terminate a hearing fetus (Middleton et al., 2001).

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reported that a temporary bite change occurs in most patients the morning after removal of the appliance, and permanent occlusal changes have been observed after longterm treatment with OAs in individual cases [19].

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This study differed from others where NE was achieved in that the birds were given liquid inoculations rather than cultures mixed with feed (Chalmers et al., 2007; Cooper & Songer, 2010).

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Prolonged imbalance of systemic hemodynamics and insufficient postprandial sympathetic activation might cause PPH (Jansen and Lipsitz 1995; Umehara et al. 2014; Hirayama et al. 1993; Mathias 1991).

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…reflect early face processing mechanisms related to the structural encoding of faces (Bentin and Deouell, 2000; Bentin et al., 1996; Eimer, 2000a; Holmes et al., 2003) and has been found to be insensitive to changes in facial expression (Eimer et al., 2003; Holmes et al., 2003) or familiarity…

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Our results were consistent with the findings in the literature that visual impairment is common among patients in rehabilitation facilities (Cox et al., 2005; Grue et al., 2009; Lieberman et al., 2004; Lotery et al., 2000; Park et al., 2005; Squirrell et al., 2005; Wainapel et al., 1989).

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All femurs were fractured by simulating a fall on the greater trochantor in a modified Hayes-fall configuration (Courtney et al., 1995).

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The potential for BCL-xL to modulate other channels in the outer mitochondrial membrane is suggested by the finding that BCL-xL regulates the open state of the mitochondrial voltage-dependent anion channel (VDAC) in synthetic membranes (Degterev et al., 2001; Vander Heiden et al., 2001).

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This is in agreement with some results where different antibiotics led to less negatively charged zeta potential in Gram-negative bacteria as a consequence of modification or complete loss of LPS and/or lipid A from the outer membrane (Winfield et al., 2005; Gooderham and Hancock, 2009; Moffatt et al., 2010).

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Depression Assessment The Montgomery-Åsberg Depression Rating Scale (MADRS) [13] is increasingly employed in clinical research since results from earlier studies had suggested that the scale could be superior to the traditional HAMD17 with respect to sensitivity to change [13,14,15] and other psychometric properties [16].

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These results are consistent with findings that there is a selective migration of stimulated lymphocytes to specific effector sites of the mucosal immune system (31).

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To reduce indels at off-target sites, double nicking of opposite strands by the RuvC dead mutant Cas9D10A with two gRNAs has been proposed (Ran et al. 2013a; Shen et al. 2014).

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For example, the second version of the Microsoft Kinect (Kinect V2) is one of the most low-cost and high-speed Time-of-Flight (ToF) sensors in the market [3].

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GFP-Pex34p, like the peroxisomal matrix protein Pot1p, localized preferentially to a 20,000 × g pellet (20KgP) fraction enriched for mature peroxisomes and some forms of immature peroxisomes (Tam et al., 2003; Vizeacoumar et al., 2003, 2004) (Figure 1B).

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In this study, all coated NiTi wires showed more deflection with the unloading force than the loading force, which is consistent with previously reported
results (Lim et al., ’94; Krishnan and Kumar, 2004; Elayyan et al., 2008, 2010; Alavi and Hosseini, 2012; Wilkinson et al., 2012).

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[8] investigated the thermal decomposition processes of 10 types of natural fibres commonly used in the polymer composite industry.

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The evaluation of the impact in the accuracy of the node’s response has been performed for each supported frequency by comparing the results with our reference model programmed in Matlab which mimics the node’s architecture and is already used in [3], [4], [5] and [6].

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Mothers with incomplete socio-demographic or labor data (n = 36), caesarean sections (n = 42) or exceptionally long labor (> 24 hours, n = 1) were excluded because labor has been reported to influence lymphocyte distribution [15], leaving 1,397 subjects for this study.

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This conclusion is consistent with the results and conclusions of Fu et al. (2002) who allowed N-22 patients 3 mo to adapt to an octave shift.

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…role, with local effects of dust and land surface changes having potentially intensified drought conditions during the Dust Bowl era, although the importance of these factors is still under discussion (McCrary and Randall 2010; Broennimann et al. 2009; Cook et al. 2009; Hoerling et al. 2009).

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Another clinically important feature is the length of the MBs, sometimes referred as the width (Mohlenkamp et al. 2002; Ozbag et al. 2002; Ozbag and Kervancioglu 2004).

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This design captured 11,383,697 bp within the non-recombining malespecific Y-chromosome, consistent with regions genotyped by previous Y sequencing studies [41] and the Y positions placed on the phylogenetic tree by the Y Chromosome Consortium [28].

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Straight lines on these semi-log plots are indicative of exponential distributions [4,36].

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The Extended Yale B [14] dataset contains frontal face images of 38 individuals each under 64 different illumination conditions.

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2003; Maier 2003), but such capability was rarely reported for cold-adapted isolates (Yakimov et al. 1999; Pini et al. 2007; Cai et al. 2014).

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[27], the Lineweaver-Burke equation was used to calculate the maximum deformability (EImax) and the shear stress required for one-half of this maximal deformation (SS K).

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Early-fruit removal in cotton has been used to study plant recovery potential and source-sink relation (Dong et al. 2008b).

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• Even more efficient pure TSP heuristics such as the Lin-Kernighan heuristic (LKH) (Lin and Kernighan, 1973), using the LKH implementation (Helsgaun, 2000, http://www.

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Other forms of elevated CK signaling, such as CK application or overexpression of IPT [39, 40] or KNOTTED genes [41], were insufficient to promote tubers in tomato, probably due to inappropriate local hormonal balances or to changing ratios among CK metabolites [42].

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Although MB morphogenesis involves Dscam variants lacking exons 19 and 23, past studies have shown that the Dscam 19 23 transgene, no matter which ectodomain it carries and whether it is fused with GFP at the C terminus or not, can effectively prevent sister branches from extending into the same axon bundle in single-cell clones of Dscam mutant neurons (Wang et al., 2004; Zhan et al., 2004; Soba et al., 2007).

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This finding is different from that in our previous analysis of the original survey data, in which AOD use was unrelated to major depression after controlling for other social and behavioural variables (Mao et al. 2009b).

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Given that BARE-2 is a chimera between BARE-1 and WIS-2 [25], the likelihood is that sequences adjacent to the arrays must have undergone multiple rounds of recombination.

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The 28-item Dissociative Experiences Scale–II (DES-II) measures the frequency of psychoform dissociative experiences on a 0–100 scale (Bernstein & Putnam, 1986; Carlson & Putnam, 1993).

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Rutin (3,3′,4′,5,7-pentahydroxyflavone-3-rhamnoglucoside, Figure 2) also called sophorin, rutoside, and quercetin-3rutinoside is a polyphenolic bioflavonoid, largely extracted from natural sources such as oranges, lemons, grapes, limes, berries, and peaches [30, 31].

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topology: a package for performing structural analysis – the current version contains the reporter metabolites algorithm of Patil & Nielsen [22].

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Previous work revealed that Dusp6 mutant mice exhibit increased pERK and Erm expression, skeletal dwarfism, craniosynostosis, and hearing loss [21].

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Butanol tolerance is a complex phenotype involving multiple loci (Makarova et al., 2006; Papoutsakis, 2008; Winkler et al., 2010), making the engineering of strains with enhanced tolerance to this solvent difficult.

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pro-hypertrophic effector mechanisms regulated by GATA4 is ANP [14] which is in turn suppressed by sorafenib treatment.

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Among possible explanations is the contribution of sex hormones in the modulation of Tregs.34
Treg-mediated local immune evasion underpins the second finding of our study, i.e. the positive association between higher FOXP3-positive T cells and the presence of VELIPI.

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The most common reported mechanisms are CSF and hematogenous dissemination [3].

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Surveys, based on The Organisational Values Questionnaire (OVQ) developed by Reino [9] and Resistance to Change Scale (RTC) developed by Oreg [8], were sent out to 4 hospital wards in a medical clinic in Sweden.

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(Costa et al., 2013; Thabtah et al., 2004), have pointed out that the minsupp threshold often controls the numbers of rules generated and the training time consumed during the rule discovery and production steps.

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‚Ä¶and (b) Logical Memory (LM) standard scores for immediate and delayed (30-minute delay) recall subtests from the Wechsler Memory Scale‚Äî Revised (WMS-R; Wechsler, 1987) with more recent normative data for the LM subtest from the Mayo‚Äôs Older Americans Normative Studies (MOANS; Ivnik et al., 1992).

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Quinolinic acid (Sigma, St. Louis) was used to lesion the hippocampal formation and caudate nucleus (Schwartz et al., 1983) as described (Worley et al., 1986a).

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, in the massive MIMO regime, the channel becomes (nearly) deterministic and the effect of smallscale fading is averaged out [8].

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Overall, changes in pattern of species richness may disrupt marine biodiversity and ecosystems, and impact commercial fisheries (Roessig et al. 2004; Worm et al. 2006; Cheung et al. 2008b).

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In addition, a precise supracondylar osteotomy with the desired angle is a technically demanding procedure and placement of a plate requires a rather large incision [4, 10, 17, 19, 23, 30].

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[46] reported improved model performance to predict the presence of prairie fish species if information on reach and catchment scale are combined.

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Insulin resistance, defined as cellular unresponsiveness to the effects of insulin, results in increasingly higher levels of insulin needed to achieve normal glucose levels [1, 4].

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…reduced engagement of medial temporal regions during the construction of future events in depressed patients (Hach et al., 2014), which is consistent with the reduced episodic detail and vividness of mental imagery that is associated with this disorder (Holmes et al., 2008b; King et al., 2011).

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Activated PERK blocks protein synthesis by phosphorylating eIF2α [13], and the phosphorylation makes ATF4, a transcription factor, to translocate into the nucleus, and induce the transcription of genes needed to restore ER homeostasis (i.

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Flow cytometry Flow cytometric analyses were performed on dissociated embryonic pancreatic cells from MIP-GFP mice using FACSAria II (BD Biosciences) (see ESM Methods).

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Synchronization is the most commonly-used method [1], [2], [3] to eliminate atomicity violations, which is an important class of concurrency errors [34].

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To assess interobserver variability between two raters of the SYNTAX score, Cohen‚Äôs kappa statistics [27] was used after tertile partitioning of their initial SYNTAX scorings.

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Assigning economic values to an environmental function or ecological service has been widely debated, with researchers employing a variety of methodologies [9–11].

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The improved pharmacokinetic and pharmacodynamic parameters of ixazomib compared to bortezomib have made it a focus of investigation for use in combination with other pro-apoptotic agents [11, 14].

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As the rate of periapical abscesses in the CH group was the same as in the induction study [Cleaton-Jones et al., 2002] but that in the ZOE teeth was a quarter of the induction rate, there is a suggestion that ZOE is superior to CH. The higher success rate may also have been influenced by filling to the apex only, as Holan and Fuks [1993] showed clearly that overfilling with ZOE is detrimental to periapical healing. Tchaou et al. [1996] exposed standard bacterial cultures to 10 root filling materials or combinations of these.

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However, as previously discussed, choice of host species has been shown to greatly influence the outcome of a Salmonella infection, and several studies utilizing a variety of advanced model systems have shown that T3SSs are necessary for Salmonella invasion and infection of these models [17,18,19,21,22,23,26,39].

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We reviewed the radiology reports of two subsets of patients: those undergoing CT thorax (pulmonary embolism [PE] protocol) and those undergoing cervical spine CT.

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Thus, herbivory in leaves or roots can induce whole-plant changes in allelochemistry ( Bezemer et al. , 2004; Kaplan et al. , 2008a ), resulting in indirect effects on co-occurring species ( Bezemer et al. , 2003; Soler et al. , 2005, 2007 ; van Dam et al. , 2005 ).

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We evaluate our method on two collective activity datasets from [6,7] and a newly recorded dataset collected by ourselves.

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…is known to be induced by Ras and repressed by p53 signaling (Li et al. 2008) and is involved in the inactivation of extrinsic as well as intrinsic apoptosis pathways, by interacting with pro-apoptotic proteins like p53, Bcl-2, Bax, Bad, PUMA, MSH2, MSH6 and others (Ludwig-Galezowska et al. 2011).

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Similar to Krajcarski et al. (1999), Chiang (in press) concluded that increased muscular activity due to pre-loads leads to increases in trunk muscle stiffness and spine stability.

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Post-translational modification by this ubiquitinlike modifier (ULM) appears to have multifunctional effects and operates in states of tolerance to preserve homeostasis under stress (Tempé et al., 2008).

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Binding of PP1c to scaffold proteins may modulate ion channel activity (44), while at neuronal synapses, neurabins I and II (also termed spinophilin) localize PP1c to the actin cytoskeleton at the plasma membrane (1, 32, 33, 37).

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In this study, the unstimulated flow rate was significantly higher in the asymptomatic group; 0.17, when compared with 0.11 in the symptomatic ⁄AIDS group (P = 0.003).

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5 m plastic boards and were distributed in the field to be used as GCPs for UAS-based image processing [29].

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This last assumption was supported by the thymic model: flutamide exposure has an opposing effect in the thymus as compared with the testis (Olsen et al., 1998; Dulos and Bagchus, 2001).

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This pattern of shifting N and P availability has been observed in a limited number of established long-term substrate age gradients (e.g. Crews et al. 1995; Wardle et al. 2004; Selmants and Hart 2008).

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For the classical ones including DOME and SAFE rules, we used one-shot screening, while for the others, we used a sequential screening setting.

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As a novel biomechanical analysis from video recordings, a Model-Based Image-Matching (MBIM) motion analysis technique has been introduced to investigate human motion from uncalibrated video sequences (Krosshaug and Bahr, 2005).

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Other studies suggest that altering affinity to FcRn might alter the bioavailability of mAbs (Deng et al., 2010; Deng et al., 2012), and SC bioavailability appears lower in FcRn-deficient mice as compared to wild type animals (Wang et al., 2008).

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The diagnosis of cirrhosis was made based on imaging studies and impaired liver synthetic function [10].

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This may demonstrate retroperitoneal air as streaking opacities in the right upper quadrant and outlining the kidney margins and along the psoas muscle [17, 23, 25].

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The insertion of this time delay is critical because in previous work, it has been shown to allow the development of an inhibitory relationship between the outcome and the stimulus that follows; that is, it allows S1 to predict the absence of subsequent O1 delivery and S2 to predict the absence of subsequent O2 delivery; that is, stimuli trained in such manner exhibit properties (such as retardation) identical to those display by other conditioned inhibitors (Rescorla, 1969; Maier et al., 1976; Delamater et al., 2003).

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Level 1 patients require immediate lifesaving interventions, level 2 patients are in a high-risk situation, are lethargic, confused, or have severe pain, and levels 3, 4, and 5 patients need many, 1, or no resources, respectively.(19) All adult (ie, 18 years of age) nontrauma patients were eligible for inclusion to the study, if they had an ESI score of 2 or 3 and vital signs within the normal range and presented in 1 of the 2 EDs between May 24, 2007, and February 8, 2011.

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The high numbers of all three species found in MT confirm the importance of this large, lowland forest block for primate conservation and further support the proposal to restore the Mngeta conservation corridor between US and Iyondo forest, a lowland to montane forest that is contiguous with MT (Rovero et al. 2012; St. John 2008) and is currently under gazettement as forest reserve (N.

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Current evidence also indicates that shear stress activates two MAP kinases by distinct signaling pathways: activation of ERK is mediated by mechanisms involving Gai-2, protein kinases [Src, focal adhesion kinase (FAK), and protein kinase C-e], and Ras, whereas JNK activation requires Gb/g, phosphatidylinositol 3-kinase-g, tyrosine kinases (Src and FAK), and Ras (11, 14, 15, 22, 37).

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…to perform a time calibrated phylogenetic analysis, using three node constraints derived from Santos et al. (2009) in the software Beast 1.7 (Drummond and Rambaut 2007): (1) the divergence between Dendrobates truncatus and Dendrobates auratus was constrained with an uniform prior with an…

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Dense Trajectory features are formed by the sequence of displacement vectors in an optical flow field, together with the HoG-HoF descriptor (Laptev et al, 2008) and the motion boundary histogram (MBH) descriptor (Dalal et al, 2006) computed over a local neighbourhood along the trajectory.

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…by the release of SPEs and other antigens, which function as superantigens (Proft et al., 2003; Marrack and Kappler, 1990; Talkington et al., 1993; Baxter and McChesney, 2000; Eriksson et al., 1999; Darenberg et al., 2004; Norrby-Teglund et al., 2005; Zurawski et al., 1998; Ekelund et al., 2005).

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…negative correlation, such that more positive mean PBR occurred concurrently with a more negative mean NBR, is in agreement with previous studies (Klingner et al., 2010; Shmuel et al., 2002), suggesting that the magnitude of ipsilateral inhibition increases with the magnitude of increasing…

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Mouse IgG 30 lg/ml final concentration was added as control (Schmid et al., 2000; Tang et al., 2006; Yeaney et al., 2009).

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…neighbor matrices, PCNM) as predictors in our analyses as these are suggested to produce inflated R2-statistics apparently due to over-fitting (i.e. selection of too many axes,
which may overemphasise the spatial component in the data) even when forward selection is used (Gilbert & Bennett, 2010).

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c-IAP2, which has been functionally implicated in the inhibition of TNF-mediated death, is transcriptionally regulated by NF-kB (40).

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In mitochondria LDH and glycerol-3-phosphate dehydrogenase do not donate electrons to the respiratory chain, yet in bacteria they are membrane-bound enzymes transferring their electrons directly to ubiquinol (Barnes and Kaback 1970; Lascelles 1978; Doig et al. 1999; Modun and Williams 1999; Dym et al. 2000; Delgado et al. 2001; Fuller et al. 2011).

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It is also interesting to note that the proportion of frozenthawed primordial follicles (36%) found after 28 weeks of grafting is comparable to that (41%) found after 3 weeks of grafting [16].

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The results observed in the study carried out by Hallal et al. (2006), which analyzed 4452 Brazilian adolescents, are in accordance with the analyses of Davison et al. (2008).

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Since the first ON1 location in Ontario [Eshaghi et al., 2012], geographical dispersion has been reported worldwide [Choudhary et al.

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We concentrate here on the computational issues, extending the Static Sensor Field model (SSSF) [2], to scenarios in which dynamicity is of relevance.

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To alleviate this, wireless-powered strategy is proposed by making use of radiofrequency (RF) signals emitted from other communication nodes to provide stable energy supply for relay nodes [14– 16].

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The explanation for such finding is not clear, since the pellet dissolves within the proventriculus (Nir et al., 1994c), and thus it was not expected that physical form of the diet would have any effect in this portion of the gastrintestinal tract.

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This implies that about 40% of the study population living in the North would  benefit  from  increasing  the duration  of  solar  exposure  as presented previously  [16].

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Although they mimic many phorbol ester effects, including inhibition of cell-cell communication (25, 26), they have been reported not to induce differentiation of HL-60 cells (27) or to inhibit maturation of granulosa cells (28).

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The observed levels of heavy metal variation in soil samples could be attributed to the varying amount of metals in the irrigation water as well as other agronomic practices of the respective areas (Yadav et al. 2013).

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There is a gradual increase in the double phosphorylation of the Thr-Glu-Tyr motif, characteristic of activated kinases such as ERK1, 2 and 5 in two proteins of 80 and 105 kDa in capacitating human spermatozoa (de Lamirande and Gagnon, 2002; Thundathil et al., 2002, 2003).

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Homeoproteins contain a highly conserved, 60 amino acid peptide domain known as the homeodomain (McGinnis et al., 1984a,b; Laughon and Scott, 1984), a peptide motif conferring sequence-specific DNA binding ability to the homeoproteins (Laughon and Scott, 1984; Desplan et al.

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In informal experiments, it‚Äôs found that only inserting LN cannot achieve satisfactory adaptation results, and inspired by [11], we combine fine-tuning output layer with Full-LN/LRPD-LN based method in the following experiments.

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This translocation event is independent of the HBV nucleocapsid and can be subsequently detected on secreted virions and SVP (5, 24).

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Prominent within the HBC are the balls – events in which the houses come together to compete in various categories for cash prizes and ‘ball status’ (Galindo, 2013).

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…tRNA selection on the ribosome during protein synthesis (Blanchard et al., 2004) (reviewed in Johansson et al., 2008; Rodnina et al., 2005), acetylcholine receptor desensitization (Dilger and Brett, 1990; Matsubara et al., 1992), and subunit rotation of F0F1-ATP synthase (Diez et al., 2004).

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This prolongs the circulation time and potential for interaction of the antigen with APCs and may reduce the need for multiple vaccinations [3].

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For group Lasso we have adapted the implementation presented in [21] whereas for comparisons with standard multiple kernel learning, we have used the GMKL implementation presented by Varma and Babu [33].

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The first of these is a class of appearance-based approaches in which a linear subspace is used to capture the variation of a particular face due variations in illumination [8, 2, 11].

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Here we use the value of ten (because our previous study showed this is the number of items that can be managed efficiently in the browser‚Äôs sidebar [Moreau et al., 2002]).

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PKCη-C2 domain induces chondrogenic diffe-
rentiation in hMSCs The C2 domain of PKCη is thought not to affect substrate-specificity of the kinase but instead aid in its localization to membranous systems (Littler et al., 2006).

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A rook pivoting scheme as in [3] and [11] can be implemented for tridiagonal matrices, but a full rook scheme for general banded matrices would probably lead to a ”chasing” scheme as in [5] or [15] .

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The original architecture proposed in [5] has been improved in [6] by rearranging the detection method (DM) in a modular fashion and by reducing the control management.

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The three-sigma signal is triggered when any data point is further than 3 standard deviations away from the overall process average [11].

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Therefore, the equilibrium and stability analysis of neural networks with time delays has been received much interest in recent years [2, 3, 4, 5, 6, 7, 18, 19, 20, 25, 24, 30, 21, 22, 23, 33].

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Some approaches address the cause of aligning both classes and entities simultaneously: the RiMOM [66] and iliads [98] systems.

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Olfactory bulb odorant ORFs These results are consistent with previously reported studies of mitral‚Äìtufted cell responses to odorants differing in carbon chain length (Imamura et al., 1992).

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Amplified neural activity was connected to an analog-to-digital converter (Cambridge Electronic Design) and passed through an integrator circuit (Shimatani et al. 2002).

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If NusA is not present, antitermination still occurs, but in this case there is evidence that antipausing is the mechanism: Restricting elongation rate at the critical release site of an intrinsic terminator by reducing the substrate NTP concentration impairs antitermination in the absence of NusA, but not in its presence (126).

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First, depression is observed at all synaptic connections between layer 5 pyramidal neurons even though U varies from 0.1 to 0.95 (Markram and Tsodyks, 1996, Tsodyks and Markram, 1997).

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Using the identifying restrictions of Baker et al. (2012), I find that the estimated response of the economy to a shock to policy uncertainty is much larger when the last 4 years of data are included in the dataset.

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The reversal component requires orbitofrontal cortex (Dias et al., 1996; Fellows and Farah, 2003; Hornak et al., 2004; Izquierdo et al., 2004; Murray and Izquierdo, 2007).

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As for exposure assessment, underestimation is considered according to the study designs; conversely for outcome and confounding assessment, overestimation is considered (Porta et al. 2009; WHO 2007; Franchini et al. 2004; Giusti 2009).

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The TNM staging of the GBC tumors was assessed according to the American Joint Committee on Cancer (AJCC) guidelines [6].

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17Recently, Davidsson & Sibbertsen (2002) introduced a model which nests the Error Duration model of Parke (1999). One interpretation of the model is that innovations become alive again once they have died.

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The inadequacy of CCS implementation in the primary care setting, which was also reported by physicians‚Äô survey from Italy, France, and Greece [6, 20‚Äì25] and by a qualitative study from UK [26], is further strengthened by our results.

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Further comparison with the distribution of 11 -hydroxysteroid dehydrogenase type 2, which is found in the DCT and CNT (4) confirmed the different pattern of expression of RhCG in these segments (Fig.

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The use of a throat pack increased the risk of developing sore throat by more than 3 times; this finding is in contrast to previous studies in which the presence of a throat pack was not found to be a risk factor in the development of POST.17,18
Our patients predominantly underwent ENT surgery, in which it is common to use a throat pack to prevent blood from trickling into the stomach and leading to postoperative nausea and vomiting.

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To block the entire time-course of morphine reward and not just the short time that the animals were in the place-conditioning apparatus immediately after morphine or saline injection, the TPP was reversibly inactivated with the local anesthetic bupivacaine, which has an effect that lasts for at least 2 h (Swerdlow & Jones, 1970; Covino, 1986), compared with the time-course (approximately 30–60 min) of the faster acting anesthetic lidocaine (Covino, 1986).

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It is also offering a wealth of new approaches such as emitters [3, 4] and sensors [5-7] in terms of THz applications.

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It conditions resistance to penicillin, cefotaxime, ceftazidime and aztreonam, and its activity is well inhibited by clavulanic acid, sulbactam and tazobactam [7, 8].

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Because ribbons and short-wavelength folds occur together at the margins of crustal plateaus and show compatible principal strain orientations [Ghent and Hansen, 1999], it is possible that they formed simultaneously, under the principle that the shortest-wavelength tectonic features represent the earliest stages of deformation.

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I estimate a vector autoregression (VAR) that includes the policy uncertainty index created by Baker, Bloom, and Davis (2012).

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Adherence to the healthy Nordic diet was measured, calculating the Baltic Sea Diet Score (BSDS) [13].

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including non-violent crimes, drug abuse, and impulsive disorder, all had increased risk for violence.[9] These results were in line with the results of the present study.

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(13) indicated that the segmental BI analysis could be applicable to the estimation of trunk SM volume.

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A shifting task was used (Hampshire & Owen, 2006) in which participants had to work out which object was the target in a stimulus set consisting of two faces and two buildings (Figure 1).

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Accordingly, almost all Arabidopsis D-type cyclins (CYCD4;2 being the only exception) contain at least one potential or poor PEST region (Menges et al. 2007) located N-terminal or C-terminal to the cyclin box, or even being present in both locations (Wang et al. 2004; Menges et al. 2007).

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…(LING)] thalamus (THA), as well as limbic/paralimbic regions [e.g. insula, superior temporal pole and inferior orbitofrontal cortex] (Table 2), which is in accordance with previous findings on functional brain networks constructed using resting-state fMRI (Achard et al., 2006; He et al., 2009b).

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q                                   (3) It worth noting that the optimal conductance parameter can be estimated by iterative methods (Tsiotsios and Petrou, 2013), however, we have a fixed κ based on the previous optimization in MRI and DTI studies (Moraschi et al., 2010; Senra et al., 2015).

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Overall, combined with the known QOL benefits of physical activity for other cancer survivor populations (7-9), the current study results suggest that interventions that successfully promote lung cancer survivors’ engagement in physical activity may increase their QOL in several domains.

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UBC13 (UBE2N) was also identified to interact with RNF168 (Doil et al. 2009).

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Sound reflections off the rat’s pinnae create frequency cues that change linearly with vertical position of sound over 60° in the frontal sound field (Koka et al., 2008).

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Previous investigations illustrated that a single afferent potential is sufficient to trigger the reflex (Krans and Chapple 2005), that spontaneous afferent potentials that occur during reflex activation of the motoneurons do not reset the reflex (Chapple and Krans 2004), and that the excitatory…

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The rats were placed on a high-salt diet (8% NaCl) except normotensive control for 9 weeks by adding 8% NaCl to the feed [20].

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The results after surgical discectomy were generally excellent.((1,7,8,10-14)) Borgesen and Vang reviewed 158 adolescent patients reported in the literature and in their series.

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Other sources of stress such as nutrient runoff, sedimentation, overfishing, and ocean acidification appear to interact with heat stress to change the bleaching threshold [11,18,24,25].

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…on cells of the CA1 subregion (Barnes et al., 1997; Shen et al., 1997; McEchron et al., 2001; Rosenzweig et al., 2003) or have combined the data obtained from the CA1 and CA3 subregions for analytical purposes (Tanila et al., 1997a; Oler and Markus, 2000; Wilson et al., 2003, 2004, 2005).

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Executive function skills rely heavily on frontal lobe development (Goldman-Rakic, 1987; Casey et al., 1997; Rubia et al., 2003), which has been noted to peak in structural maturation during adolescence (Giedd et al.

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6 See for example studies of Morocco by Haddad and Harrison (1993); Venezuela by Aitken and Harrison (1999); Bulgaria and Romania by Konings (2000); Russia by Yudaeva et al. (2003); the Czech Republic by Kosova (2004); and China by Abraham, Konings and Slootmaekers (2006). In the Chinese case, Abraham, Konings and Slootmaekers (2006) find positive horizontal spillovers for certain types of firms.

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Tidal freshwater marshes have been found to have higher rates of carbon storage than brackish or saline tidal marshes (Bridgham et al. 2006; Craft 2007; Trulio et al. 2007).

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Costunolide (1) has been studied various inhibitory activities of melanogenesis (Choi et al., 2008), production of tumor necrosis factor-alpha and interleukin6 (Pae et al.

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Measurement of the Tp-Te interval was obtained from leads V2 and V5, corrected for heart rate (cTp-Te).(11) The Tp-Te/QT and cTp-Te/QT ratios were calculated from these measurements.

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It may also be that disease activity in psoriasis correlates with levels of CD-associated antibodies (Lindqvist et al., 2002; Woo et al., 2004).

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COQN-term anti-COQ7(1-37)specific antibodies were derived using the same protocol but starting with antiCOQ7 (Santa Cruz, sc-135040).

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In a second experiment, ten Antarctic prions were rendered anosmic using an injection of zinc sulphate solution into the olfactory chambers (Bonadonna et al. 2001), and ten other birds, acting as controls, were sham-treated.

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Stem Cell Reports This is an open access arti without the use of transgenes remain dependent on fibroblast growth factor (FGF) or transforming growth factor b (TGF-b) (Chan et al., 2013; Gafni et al., 2013; Valamehr et al., 2014; Ware et al., 2014; Duggal et al., 2015; Qin et al., 2016), which is a major property of the primed state (Vallier et al.

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Enzyme immunoassay (EIA) was performed for quantitative identification of 6-keto-PGF1 (the stable degradation product of PGI2) and TXB2 (the stable degradation product of TXA2) as described previously (20, 25).

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…et al. (2003)
herbimycin A non-receptor type PTK 8–12 10 Leclerc et al. (1997) ERK Pathway CGP78850 competes for Grb2-SH2 0.043 30 Gay et al. (1999); de Lamirande and Gagnon (2002)
Sulindac sulphid Ras-Raf Interaction – 100 de Lamirande and Gagnon (2002) ZM336372 Raf, competitive inhibition 0.07–…

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Mental health status was assessed using the Japanese version of the Kessler 6 (K6) scale [20], a screening scale for psychological distress that can effectively discriminate between cases and non-cases of Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) disorders [21].

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‚Ä¶identification and analysis of putative promoter sequence was conducted using the ProScan suite of programs (http://thr.cit.nih.gov/molbio/ proscan/) using the default settings [Prestridge, 2000] as per our previous gene characterization protocols [Philibert et al., 1999; Philibert et al., 2000].

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PTOV1 can bind to flotillin-1 (Santamaria et al. 2005) and the 14-3-3 protein (Benzinger et al.

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In general, our results on the effect of contact compounds from grapes differ from those published by other authors (Maher and Thiery 2004a, 2006; Maher et al. 2006; Moreau et al. 2008).

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That is, experience can maintain an existing ability (Pascalis et al., 2005), but research is needed that examines whether, and under what conditions, experience leads to the ‘‘re-emergence’’ of perceptual discrimination of previously unfamiliar faces of another species once perceptual narrowing…

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Fusion between the virus membrane and the plasma membrane of intact cells can be induced by a drop in pH, and in this case the cells were infected (White et aL, 1980).

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, 2000), which interacts with other proteins involved in neuronal migration, cell-signalling and -proliferation (Ishizuka et al., 2006), cytosceletal and synaptic function, neurite extension (Murdoch et al.

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evaluate the semantic clarity of each filter, we chose three benchmark datasets with landmark3/part annotations for training and testing, including the ILSVRC 2013 DET Animal-Part dataset [36], the CUB200-2011 dataset [30], and the Pascal VOC Part dataset [3].

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Overexpression of Skp1 or absence of pathway activity drives the O2 requirement up to 1821% (near ambient level), whereas decreased Skp1 or overexpression of PhyA drives the O2 requirement down to 5% or less [5,10,11].

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Earlier, we studied potential four- and three-stranded architectures that may participate in GQ folding pathways (60,61).

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The potential tectonic control reported by Finnegan et al. (2008) for the eastern Himalaya has also been suggested for the Eastern Cordillera and the upper Beni region (Safran et al. 2005).

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Baird et al. (2007) hypothesize that symbiont community shuffling to clade D may persist only as a result of enduring changes in environmental conditions, e.g. repeated warm summers.

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…and SR19 (5′-[880]GGGATAGAGACACCAATACC-3′) to yield a 740-bp fragment for exon 3 (the nucleotide numbers in square brackets refer to the deposited genomic DNA sequences) (Ohye et al. 1998; GenBank accession numbers AB017547, for exons 1 and 2, and AB017548, for exon 3).

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Doses were based on pilot studies as well as data reported in the literature (McGregor and Roberts 1995).

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Output: method