As otoliths grow, elements from the surrounding water mass become incorporated into the aragonite matrix, creating a chemical fingerprint that can be used to distinguish among geographic regions [36,37].

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Letters
 The Role of Ocular Perfusion Pressure in Glaucoma Cannot Be Studied With Multivariable Regression Analysis Applied to Surrogates
 Ocular perfusion pressure (OPP) is not easily directly measurable, and the difference between blood pressure and intraocular pressure (IOP) has been suggested as a simple surrogate of OPP.1 We write in relation to publications in this journal2,3 and elsewhere4 that have reported a significant association between OPP surrogates and glaucoma.

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In this sense, coffee is a complex mixture, with dozens of chemicals appearing in the circulatory system after consumption, absorption and metabolism, and where individual circulating metabolites may exert different effects within the human body [20, 21].

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Accumulating evidence suggests that cellular senescence is one of the intrinsic safeguards against cancer progression as well as contributes to tissue/organism aging and age-related disease [3].

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Previous studies have only found an increased anteroposterior diameter of the left atrium in patients with IAF as compared to the general population(6); this condition could act as an anatomical substrate favourable for the development of IAF.(7) Epidemiological studies have shown that hypertension is the most important risk factor involved in the development of AF.

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Because numerous reports have demonstrated impaired sensory filtering in schizophrenics (Adler et al., 1982; Freedman et al., 1987; Snyder, 1973; Solomon et al., 1981; Sorensen et al., 1993), the results of the present study suggest that activation of 5-HT2 receptors could improve sensory filtering in these individuals.

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…within health care organisations within Victoria showed a general lack of strategic HRM, including HPWS, within the health care organisations of this state (Leggat et al., 2008), with larger hospitals demonstrating fewer aspects of HPWS than smaller community health services (Leggat et al., 2006).

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were noted to influence pain perception in previous studies (Nafiu, Shanks, Abdo, Taylo, & Tremper, 2013; T√ºfekci et al., 2009) were obtained by a research assistant from the medical records.

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Our findings also confirm results from much less extensive studies in the European brown bear (Hissa et al. 1998) and the grizzly bear (Gardi et al. 2011).

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Our results showed that the treatment response of the 5 mg/day vortioxetine group was greater than the placebo group, and the pooled ES of the studies (Katona et al. 2012; Mahableshwarkar et al. 2013; Henigsberg et al. 2012; Jain et al. 2013) demonstrated the antidepressant efficacy of vortioxetine.

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Utilizing previously established coculture conditions (21), this study shows that 1) rat PAECs but not PASMCs synthesize serotonin, 2) PAEC-derived serotonin passes through myoendothelial gap junctions into PASMCs, and 3) PAEC-derived serotonin activates TGF- signaling and promotes PASMC differentiation.

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Given the known deWcits in cortical processing of prosody in children with ASD (Erwin et al. 1991; Wang et al. 2001; Kujala et al. 2005; Korpilahti et al. 2006), one may speculate that the disrup-

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FAF changes in early age-related maculopathy (ARM) and in atrophic ARMD [7, 10].

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Dead individuals were removed, surface sterilized with 5.2% sodium hypochlorite, rinsed twice with sterile water, and plated on potato dextrose agar to confirm that mortality was due to infection by M. anisopliae (Rosengaus et al. 1998).

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We also estimated the prevalence of other risk factors for falls and fractures, including osteoporosis, Parkinson’s disease, ataxia, visual impairment, deafness and delirium, using ICD-10-AM codes also tested on the VAED [25].

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Previous Peruvian studies have documented that children experience high rates of Giardia reinfection (19) and that children attain adult levels of seropositivity against Giardia by 6 months of age (30).

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10 Note, Filippini and Hunt (2012) utilize the Mundlak’s modification to the Pitt and Lee (1981) model instead.

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[4] The use of multiple maneuvers including swallowing water, separate-day imaging, oblique and lateral imaging, correlating with other imaging techniques, is essential for accurate diagnosis.[26] In the current study physical examinations revealed no palpable midline neck mass in any of the subjects, and postoperative US revealed no abnormally enlarged lymph nodes in the central compartment of the anterior neck.

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Although McCartney and Lessios (2004) suggested a number of alternative sources of selection on E. lucunter bindin, their samples included only Panamanian populations, leaving reinforcement as a possibility.

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In general, results were consistent with any of the following possibilities: (1) language delays in ASD are not a result of implicit learning deficits; other research has proposed a variety of alternative mechanisms for atypical and delayed language development in ASD, including, for example atypically developed joint attention (Charman 2003), and poor motor control (Gernsbacher et al.

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…genes identified to play a specific role in the development of peptidergic neurons was dimmed (dimm), which encodes a basic helix–loop–helix transcription factor that is required for the differentiation of diverse peptidergic neurons (Hewes et al. 2003; Park et al. 2008; Hamanaka et al. 2010).

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The expression of ISL1 was significantly higher in gastric adenocarcinoma by immunohistochemistry and bound up with depth of invasion, lymph node metastasis, TNM stage and histological grade [16].

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Potassium (Kþ) channels have the greatest amount of diversity among ion channels in the plasma membrane, which are encoded by over 75 distinct genes [2].

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We establish consistency in the well specified case by generalising the arguments of Sriperumbudur et al., 2017 to the vector-valued RKHS.

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Its levels can also be elevated during menstruation or pregnancy, as well as in other benign gynaecological conditions, such as endometriosis, peritonitis or cirrhosis, especially with ascites production (Tuxen et al, 1995, Meyer and Rustin, 2000).

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Anemone survival is crucial for the survival of the fish (Mariscal 1970; Elliott et al. 1995; Buston 2003a).

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…others (Roshan et al. 2003; Fisher et al. 2002), the results of SICI with threshold tracking showed two periods of maximal inhibition at ISIs 1 and 3 ms. Fisher et al. (2002) demonstrated peaks at 1 ms and between 2.2 and 2.8 ms while Roshan et al. (2003) found peaks of inhibition at 1 and 2.5 ms.

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Some international studies [39‚Äì41] that did assess the relationship between patients‚Äô knowledge about oral anticoagulants and anticoagulation control using the Rosendaal Method had results in line with our finding of no significant association between them, while a few other international surveys found that knowledge positively affects the INR control [23, 42, 43].

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Moreover it is not only difficult to achieve site specific functionalization [15] but also align opposite edges of a GNR while rolling for nanotube formation [16] as suggested ear-

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The definition we used for prolonged postoperative ileus followed the recommendations published by Vather et al. (2013): the absence of passage of flatus/stool or inability to tolerate oral diet ‚â• 4 postoperative days.

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Queuing networks is one of the most used tools to model Discrete Event Dynamic System (DEDS), Cassandras and Lafortune (1999), useful to model realities like communication networks or manufacturing systems.

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Whereas Qazi et al. (2013) primarily manipulated channel selection and current levels within each temporal region in order to investigate the impact of noise-induced errors in sound coding strategies, the present study manipulated the gains that are applied in
a preceding noise reduction stage in…

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However, a previous discussion of time-resolved FTIR data (Dioumaev and Braiman, 1997a) argued that a similar transition with t .

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Spacers specifically determine the targets of CRISPR-mediated immunity (Barrangou et al., 2007; Brouns et al., 2008; Marraffini & Sontheimer, 2008), most likely after a base-pairing recognition of the complementary sequence.

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An option is ‘targeted surveillance’ of patients with severe underlying disease or risk factors for ESBL-E carriage at admission [17,18].

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phospholipid degradation following tissue damage such as an ischemic brain insult (Horrocks et al., 1981).

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As in previous experiments (de la Fuente et al. 2007b, 2008), RNAi with UBQ, EF-1a, and SUB increased R. microplus mortality and reduced oviposition when compared to controls (Table 1).

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Finally, quantitative analyses were restricted to EHMs with a latency larger than 65 ms (rejecting 11 responses out of 251), which is the shortest visuo-motor delay based on the estimates of afferent and efferent delays of SC motor neurons (Guitton & Munoz, 1991; Munoz et al., 1991).

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Our water chemistry results are consistent with results published by Basterrechea (1988a) for Lakes SalpeteÃÅn,
 YaxhaÃÅ, Atescatempa, and Ayarza.

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The most extensive studies have characterized chick brain BgtRs in which three bands with molecular weights of ;50, ;57, and ;67 kDa were observed (ContiTronconi et al., 1985; Gotti et al., 1991, 1992).

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In [10] the authors analyzed the time-varying wavelet transform through changing the two-band filter banks used in the tree-structured implementation of DWTs with an simple example.

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VDR
downregulation was not found to be driven by copy number variation or mutation and
thus epigenetic mechanisms may be primarily responsible for altered expression(Long
and Campbell, 2015) (Long et al., 2014).

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In line with our data, junior resident level has been shown to be associated with increased operative time for both open and laparoscopic hernia repair in adults compared with more senior residents.(13) Similarly, junior cardiac surgery fellows were found to have longer operative times compared with the senior fellow when performing coronary artery bypass grafting.

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The level of the participants‚Äô dementia varied from mild to extremely severe, as assessed by Mini Mental State Examination (MMSE) [20], Clinical Dementia Rating (CDR) [21] or Global Deterioration Scale (GDS) [22].

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(2010). They collected verbal estimates and free-hand measures of outdoor hills using the present device for a set of campus paths ranging from nearly flat (0.5°) to fairly steep (8.6°). Note that the perceived orientation of any specific outdoor hill may depend on a variety of factors in addition to its physical slant (e.g., curvature and viewing distance), but if the free-hand measure represents the NSE orientation, then we should expect the relationship between verbal estimates and free hand (NSE) estimates to remain similar to that observed for near surfaces. In other words, we should be able to make a prediction about the verbal estimates based on the free-hand estimates. ----- Figure 7 to be inserted here ----Figure 7 shows Stigliani et al.’s (2010) numeric estimation data for outdoor slopes plotted against the corresponding free-hand estimates (NSE) for each physical path (physical path inclination is shown next to each data point).

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Second, HASM cells in culture, when observed between 3 and 6 h after plating, were not spindle shaped or aligned in parallel, as they are at the tissue level (5); instead, they were irregularly shaped (Fig.

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These results are inconsistent with those of previous studies, which generally suggest that leptin is associated with sympathetic activation [11].

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polycystic lesions showing extensive growth in the extracerebral CSF spaces and secondary invagination of the brain [13].

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The 47 pixels whose NDVI values were greater than 0 and less than 0.2 were seen as non-vegetation pixels (Tsai et al., 2007; Noujdina and Ustin, 2008).

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) Botswana[102], Nigeria[87], South Africa[101], Zimbabwe[94] Comoro rousette (Rousettus oblivious) Comoros[107] House mouse (Mus musculus) Kenya[124], Madagascar[118] Pigs (Sus scrofa domesticus) South Africa[104, 122] Rusty-bellied brush-furred rat (Lophuromys sikapusi) Cameroon[109] L.

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Our algorithm extends the work [25] which addresses the traditional semi-supervised learning problem where labeled data is from a single source.

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Contrarily for the TRECVID 2010 dataset we have used linear SVM to learn from a suitable feature map (homogeneous kernel map) built by the histogram intersection kernel [137, 138].

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The application that motivated the calculation of g J was the identification of dot-depth one languages [49] according to a natural hierarchy of plus-free languages introduced by Brzozowski [29].

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To quantify habitat indication for each native and non-native species, we used an objective method that we developed in previous studies of effects of invasions, land management practices, or environmental conditions on plant species composition in a variety of ecosystems in MS (Brewer 2008; Brewer and Menzel 2009; Brewer 2011; Brewer et al. 2012).

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However, the reduction of GnRHR gene expression during inflammation in the PT may also result from the direct action of pro-inflammatory cytokines and stress, because both IL-1β and corticotropin-releasing hormone (CRH) were shown to suppress GnRHR expression [14,38,39].

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The vast majority of the Dot/Icm T4S effectors that gain access to the host cell cytoplasm are not absolutely required for bacterial intracellular replication, as the individual effector mutants do not replicate to lower numbers than WT bacteria (91).

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However, there are inevitably errors or uncertainties in spatial data, which are used to represent reality world (Goodchild and Gopal, 1989; Guptill and Morrison, 1995 Burrough and Frank, 1996; Shi and Liu, 2000).

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5 (Duarte et al., 2004; Hamada et al., 1999; Hrabe de Angelis et al., 1997; Xue et al., 1999).

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Candida spp. has been reported as one of the most common pathogens that cause hospital-acquired bloodstream infections in patients undergoing surgical or chemotherapeutic interventions and/or with underlying immunological deficiencies (Wisplinghoff et al., 2004; Pfaller & Diekema, 2007).

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By Perron’s theorem [27], the eigenvalue 1 is of multiplicity 1 and is the unique eigenvalue with maximum magnitude.

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This would also be consistent we our earlier study showing a threshold effect in electric field sensitivity, as evidenced by a sigmoidal dose–response curve (Kindzelskii and Petty 2000), which is a widelyrecognized feature of systems exhibiting cooperativity.

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Two possible interpretations of these observations are (a) the spontaneous hydrolysis of PMSF (James 1978) and/ or (b) the existence of spontaneous reactivation (Estévez and Vilanova 2009).

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NC is thought to be the result of growth dysregulation affecting the mesodermal portion of the pilosebaceous unit (2), leading to a follicle-based hamartoma with imperfect differentiation in the epithelial portion (4).

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Greater scapular upward rotation was demonstrated in rotator cuff dysfunction [14, 40, 41] and anterior glenohumeral joint tightness [13].

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Partial and total inbreeding coefficients were calculated with the ENDOG program (Gutierrez et al., 2003), that uses the algorithms described by Meuwissen et al. (1992) y Lacy et al. (1996).

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The thromboembolic complication was the first symptom of HIT preceding a subsequent platelet-count decrease in four patients [22, 25, 36].

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unstructured in HSPB6 and predicted to have similar properties in HSPB1 (18), that is essential for this preferred association.

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Cyclin D1 protein is overexpressed in more than 50% of human BCs [28] and has been frequently detected early in breast pre-neoplasias [29].

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The MEK inhibitor PD98059, prevented AR induced by LPC (de Lamirande and Gagnon, 2002) but not by A23187 and zona pellucida (du Plessis et al., 2002).

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GST-fusion proteins comprising the C-terminus of wild-type and mutant SERTs were used for pull-down experiments carried out with SEC24C and SEC24D.

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In all previous attempts [15, 30, 34, 8, 64, 43], the overlap problem is handled by partitioning the placement area and adding new constraints to the formulation to restrict the movement of the cells before solving another optimization problem.

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mutant embryos (Deng et al., 1994; Yamaguchi et al., 1994; Sun et al., 1999; Guo and Li, 2007).

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Metal concentrations were measured using an ELAN® 6000 ICP-MS (Perkin-Elmer, SCIEX, USA) (Maher et al. 2001).

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A recent storytelling task by Hendriks et al. (2014) confirmed this overall pattern but also highlighted that other factors can modulate this effect of the discourse stages.

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…did not use any chemical, biochemical or physiological characters, but in later taxomomic studies of Aspergillus physiological tests (Klich
& Pitt 1988) and secondary metabolites (for example Frisvad 1989; Frisvad et al. 1998a, 2004; Samson et al. 2004; Frisvad et al. 2007) have been introduced.

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During the uplift of the Tibetan Plateau, river captures and flow reversals caused regional extension of the Yangtze River basin to the eastern Tibetan Plateau (Clark et al. 2004; Fan et al. 2005).

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Nowadays, there are only a few studies that have a systemic view on these accidents (Bentley 2008) and which try, by using detailed analysis (Gao and Abeysekera 2004, Leclercq and Thouy 2004, Bentley et al.

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The authors proposed that partial repairs would restore the force couple of the humeral head and increase acromion-humeral distance, resulting in dramatic changes in pain and function [16-19].

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Given that the angular spacings between adjacent views in golden angle acquisition are unevenly distributed, 610 views were used in the outermost region to fulfill the Nyquist criterion for a 240 240 image matrix (15).

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Insulin sensitivity was estimated by the insulin sensitivity index (SI) [6]; beta cell function was assessed as an index of the corrected insulinogenic response (CIR) [7] and disposition index (DI=CIR×SI) to adjust insulin secretion for SI.

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Neurotransmitter release at the NMJ is regulated by factors intrinsic to the motor neuron, including proteins that regulate intracellular signaling, as well as retrograde signals that convey postsynaptic activity levels to modulate neuronal properties (Collins and DiAntonio, 2007; Harris and Littleton, 2015; Menon et al., 2013).

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This indicates that GJIC is important for controlling the balance between proliferation and apoptosis of fibroblasts in the skin, as well as for managing the production of ECM [11].

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While many genetic correlations between body parts in Drosophila are positive (Cowley and Atchley 1990; Norry et al. 1997), an exception appears to exist for the eyes and head.

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HA monomer, consisting of two linked subunits; HA1 (~324 amino acids) and HA2 (~222 amino acids, (Webster et al., 1992), totally weighs about 60 kDa in the unglycosylated form (Sriwilaijaroen et al.

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Duschek and Schandry (2007) reported recently that impaired brain perfusion in hypotension especially in middle cerebral arteries (MCA) can cause cognitive deficits and even depression.

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Thus, the Patient Health Questionnaire-9 (PHQ-9) (Kroenke et al. 2001)‚Äîalready administered to students seeking services at the clinic‚Äîwas chosen as the screening instrument for the study.

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Wadge has proposed in [112] a fragment of higher-order Horn logic called “definitional programs” as a meta-programming language “based on Church’s Simple Theory of Types” [112], that is, the Simply Typed Lambda Calculus or λ→ [28, 6].

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[35] To document in-depth the effects that cognitive impairment has on women’s personal and professional lives.

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In particular, it has been noted that high levels of abdominal fat pose a particularly severe risk for progress to metabolic disease (12–18), whereas fat deposited subcutaneously is more benign (17,19) and may actually be protective (20).

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In a number of cases this resulted in a similar effect on transcription, namely activation of cryptic splice sites and exon skipping (Gardella et al, 1996; Posteraro et al, 1998; Terracina et al, 1998; Weil et al, 1988).

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…sample into two groups comparing those who displayed high levels of behavior problems as indexed by the Eyberg Problem or Intensity factor, using previously validated cut-off scores and mirroring the criteria applied during recruitment for the study (Burns and Patterson 2001; Dishion et al. 2008).

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Dominant and non-dominant breast categorisation was implemented by examining the magnitude of superioinferior breast displacement (the direction in which the greatest breast displacement occurred; Scurr et al., 2010) of each breast, within each participant, and assigning the breast with the greatest superioinferior displacement as the dominant breast and the least as the non-dominant breast.

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…River Capture
There is overwhelming evidence that the Indus, Brahmaputra, and Ganges Rivers, existed as separate river systems soon after the original India-Asia collision (~55–45 Million Years (MY) ago) and even before large-scale elevation of the Himalayan mountains (Clift and Blusztajn 2005).

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Group II anti-cryptococcal mAbs have been shown to enhance the function of effector cells (29, 44, 55) which likely have a primary role in host defense (56).

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For the MEC study, data for the three SNPs presented in this study were extracted from the GWA scan data generated using Illumina 660W.

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…remove excess copper and is observed by clinical symptoms such as hepatic abnormalities, neurological defects, more commonly psychiatric/behavioral symptoms (Hedera 2017), and eventually liver failure which can cause death when untreated (Chesi et al. 2016; DiDonato et al. 2002; Yu et al. 2017c).

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Comparison of Ptf1a regulation in the CNS and pancreas These findings parallel those recently reported in the pancreas, where the 2.3 kb 5 element is also active (Masui et al., 2008).

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found that about 74 % had no regrets about treatment choice although about half reported difficulty and distress in making the decision [4].

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…turkey P450 1A and 3A orthologs with respect to AFB1 metabolism in liver microsomal and heterologously-expressed systems, which are, in fact closer to humans than those from either mice and rats (Rawal et al., 2010b; Gallagher et al., 1994, 1996; Ueng et al., 1995, 1997; Yip and Coulombe, 2006).

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functions as a molecular switch that both controls the duration of the NF-nB transcriptional response (20).

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On the whole, we had better results than Winslow and Brunt [31], perhaps because all the operations were performed by a single surgeon in our series.

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32 We note that our use of the term ‘blatant’ refers to the type (and not extent) of dehumanization perceptions (see also Kteily et al., 2015).

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Recent research has shown that features of interest in physiological signals such as electrocardiogram [5], [6] and photoplethysmogram [7] can be detected accurately from these sparse pulses.

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Inclusion criteria were having erosions detected by endoscopy at enrollment into this study or having a past history of RE, and having reflux symptoms at enrollment into this study, which could be evaluated using the 8-item Short-Form Health Survey (SF 8TM, Japanese translation) [12, 13] and the Frequency Scale for the Symptoms of GERD (FSSG) [14].

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In addition, they are in keeping with reports that Ser19 phosphorylation is low in swine carotid arteries relaxed with forskolin (Meeks et al. 2008) as well as in a-toxin permeabilized mouse tail arteries relaxed with urocortin and cAMP (Lubomirov et al. 2006).

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In the domain of supply chain, logistics, and operations management, the approach has been popularized by Holmström et al. (2009),
leading to promising initial applications (e.g., Finne and Holmström, 2013; Schleper and Busse, 2013; Tanskanen et al., 2015).

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While quantitative changes in bacterial numbers in the soil surrounding the AMF are seldom reported, changes in bacterial composition may occur (Olsson et al., 1996; Andrade et al., 1997).

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Up to now, studies of brucine are mainly focused on reducing the central toxicity by transdermal administration and improving the efficacy through a novel drug carrier [3, 10].

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On the other hand, phospho-GSK-3β has recently received attention as a common mediator in protective mechanisms activated by different interventions, including IPC and ischemic postconditioning (IPost-C) [3,4,11,12].

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Given the tree and the MSA, the Rate4Site algorithm (16) is used to calculate positionspecific evolutionary rates under an empirical Bayesian methodology (17).

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It has previously been shown that members of the ADAM family of metalloproteinases are expressed in adult thymi [7,8,9,10,12,13] and that ADAM8 is expressed in fetal and adult thymi [12,13].

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For PLP-based features, we used mixtures of 128 for baseline, SWCE and Multi-peak and mixture of 64 Gaussians for the Thomson_1 and Thomson_2 systems.

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The invaded range of the species
is well known (e.g. Brown et al. 2011), but the native
range of the species in Asia has until now been poorly
understood (Poutsma et al. 2008).

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Similar results were found in other restinga areas of the State of Rio de Janeiro, where Eugenia and Erythroxylum (Erythroxylaceae) were pointed out as super host plants (Maia, 2001; Oliveira and Maia, 2005).

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lingual phrase-based machine translation system with a reranking post-processing step8 (Wubben et al., 2012) and Hybrid, a model which first performs sentence splitting and deletion operations over discourse representation structures and then further simplifies sentences with PBMT-R (Narayan and Gardent, 2014).

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Sixteen other subjects took part in studies of lower intensity but more prolonged exercise comprising 45 min at 70% _ VO2peak then to fatigue at 90% _ VO2peak [3, 4].

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This was surprising since sLex bearing LGALS3BP has been shown to be involved in the rolling of the ZR-75-1 breast cancer cell line on endothelial cells (8).

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2002) or by enforcing constitutive expression of Dnmt1 in cells (Feltus et al. 2003) or of the CpG-specific bacterial DNA methyltransferase SssI in isolated nuclei (Fatemi et al.

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But from the experimental results in Wang et al. [2014], we find that R1MP outperforms these algorithms.

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qRT-PCR of androgen regulated genes (TMPRSS2, KLK3), and DNA repair genes (PRKDC, POLE2, FANCI), were carried out as described previously (4) using the following primer pairs: GAPDH (F: GGAGCGAGATCCCTCCAAAAT, R: GGCTGTTGTCATACTTCTCATGG); TMPRSS2 (F: TACTCTGGAAGTTCATGGGC R: GTCATCCACTATTCCTTGGCT); KLK3 (F: TGAACCAGAGGAGTTCTTGAC R: TGACGTGATACCTTGAAGCA); PRKDC (F: AGCTGGCTTGCGCCTATTT R: GGGCACACCACTTTAACAAGA); POLE2 (F: CTGCTCCGTGGTGAAGCTAT, R: ATTCCTGGACTGCTGCTTCC); FANCI (F: TTCTCACTGCTCTTTTCAGGGAT, R: GCCCTGTTTCCTTTAGCTGC).

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Here we analyse the sustainability of the initiative over a 32-month period of operations, using a modified version of a framework developed by Sarriot et al. (2004a).

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…independent real factor analysis (or noisy ICA), together with the corresponding criteria for the number of independent factors (Xu, 1998b, 2000, 2001a); as well as (e) several extensions of LMSER learning and the corresponding criteria for the number of hidden units (Xu, 1993, 1998b, 2000, 2001a).

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8
To validate the quality of our categorization, the next section discusses series of experiments that compare the performance of the vector space categorization approach with one of the top classifiers, Naïve-Bayes (Friedman et al., 1997).

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Critically, however, our reliability results converge with other investigations in the literature using a variety of methodologies (e.g., Brown et al. 2014; Enock et al. 2014; Schmukle 2005; Staugaard 2009).

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On the other hand, there were reports showing that chewing rate and eating behavior did not differ between people with high and normal BMI [64, 65].

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Modelled HO2 concentrations were generally found to agree with observations (Mao et al., 2009).

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Recent studies found that dynein which was involved in neuronal migration may play an important role in the function of BDNF (Tsai et al., 2007; Zhou et al., 2012).

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Twelve studies [3, 11, 15, 44, 50, 56, 60–62, 67, 69] reported incorporating some form of cultural adaptation salient to AAs including recruitment of only AA participants [60–62, 67], culturally specific diet and PA modifications [3, 11, 50, 56, 60, 61, 67], cultural sensitivity training for research staff [44, 56], employing AA case managers and interventionists [3, 11, 50, 60, 67], special attention to religion and spirituality [60, 62], AA community-focused field-trips to grocery stores, parks, and so forth [50], selection of study site in anAA community [67], and the formation of a minority implementation committee [56].

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, 1993), and the nuclear mitotic apparatus (NuMA) proteins (Lydersen and Pettijohn, 1980; Compton et al., 1992; Yang and Snyder, 1992).

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This protein was essential for the maintenance of the kDNA during cell division (12).

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Periodic boundary conditions were applied and electrostatic interactions were treated using the smooth particle mesh Ewald method [41] with a grid spacing of 1 Å.

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The same 24 color pictures of Barbary macaques used in Pascalis et al. (2005) were used in this experiment to create 12 pairings (6 easy and 6 hard pairings).

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To understand the relationship between exercise intensity and affective responses research has focused on quantifying pre- to during and pre- to post-exercise changes in affective responses at different exercise intensities [3-14].

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They have been identified as one of the major threats to the maintenance of biodiversity and ecosystem functioning (Ruiz et al., 1997; Mack et al., 2000).

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The Tsimane’ reported being healthy at the time of the study but, in the past, they might have suffered from otorhinolaryngological or other diseases impairing olfaction [19].

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Imaging studies showed reduced activation of visual cortices during vestibular stimulation (Brandt et al., 1998; Brandt, 1999; Bense et al., 2001), and this was hypothesized to be a cortical mechanism contributing to stabilize visual images during self-motion, along with brainstem reflexes (such as the vestibulo-ocular reflex).

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The joint distribution differs significantly from the earlier distribution, developed in Forest et al. (2002) and used in Webster et al. (2003), because the model simulations for the twentieth century used by Forest et al. (2006, 2008) include several additional forcings.

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Our recent characterization of spike frequency adaptation intrinsic to VSMN led us to hypothesize that the duration of phase 2 should be positively correlated with increasing phase 3 frequency (Krans and Chapple 2005).

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Total IgA fractions from all sera were purified as previously described [13] and used in experiments at a concentration of 1 μg/ml.

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For example, Kawato et al. (1990) suggested that movement trajectories can be projected using critical via-points through which the trajectory has to pass at a certain time, rather than in terms of the moment-by-moment dynamics of the implemented movement trajectory. Optimal trajectories can then be learnt by applying local optimising principles for getting from one via-point to the next. In this way, impoverished predictions can be used to monitor rich implementations. In the same way, language users might predict particularly crucial aspects of an utterance, but the aspects that they predict will depend on the circumstances. More generally, Meyer & Hagoort question the value of predicting one’s own utterance. They argue that prediction is useful when it is likely to differ from the actual event. This is the case when predicting another person’s behaviour or when the result of one’s action is uncertain (e.g., moving in a strong wind). But they argue that people are confident about their own speech. Meyer & Hagoort admit that they will tend to be less confident in dialogue, and we agree. But more important, we argue that the behaviour of the production implementer is not fully determined by the production command, because the complex processes involved in production are subject to internal (“neural”) noise or priming (i.e., influences that may not be a result of the production command). Assuming that these sources of noise do not necessarily affect forward modelling as well, predicted speech may differ from actual speech. In addition, prediction is useful even if the behaviour is fully predictable, because it allows the actor to plan future behaviour on the basis of the prediction. In fact, we made such a proposal in relation to the order of heavy and light phrases (see sect. 3.1, target article). Hartsuiker claims that our account incorrectly predicts an early competitor effect in Huettig and Hartsuiker (2010). His claim is based on the assumption that Response/Pickering & Garrod: An integrated theory of...

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These results are in agreement with those reported by Schmalz et al.(20), who did not observe any negative effect in the viability of fibroblastkeratinocyte cells cultured onto pure Pd during 24 h.

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Synaptic heterogeneity is not the only evidence for plasticity of several synaptic parameters: (1) Hebbian pairing of pre and postsynaptic neurons was shown to result in a selective increase in low frequency synaptic transmission (Markram and Tsodyks, 1996) which is due to a specific change in U (Tsodyks and Markram, 1997); (2) while presynaptic regulation of neurotransmitter release is typically considered as a mechanism to block or enhance transmission between neurons, this action rather serves to change the frequency dependence of transmission; (3) paired pulse experiments that demonstrated changes in paired pulse ratios rather demonstrated changes in frequency dependence; (4) we have recently found that an initial stage of LTDa is preceded by a selective loss of facilitation (LTDf) (A.

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This technique is also applied to chemoembolization of tumor-feeding extrahepatic collateral vessels that develop with an incidence of approximately 25% (5,7), and chemoembolization of these ves-

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This antibody has been shown to detect a protein of 70 kDa when wild-type ChAT was expressed in COS cells (Ohno et al. 2001).

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In this review article, we first briefly explain the steps of a well-performed SR/MA [1] and then apply them to the topic of VUR.

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First and foremost, consistent with our previous work (Leonard and Baum, 1998; Leonard et al., 1997a, 1997b), the results of this study represent yet another demonstration of the ability of RHD individuals to use a given type of contextual information, even under conditions of increased
processing…

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Given that a higher prevalence of favourable rs12979860 genotype has been found among healthy individuals when compared to HCV-infected patients [41], it is plausible that our results support the notion of a protective effect of IL28B ‚Äúgood‚Äù response genotype within the Uruguayan population, as has been previously suggested by others [10, 44].

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Modified Cox-Snell residuals were used with dropout modeling in previous applications [9, 22], however they do not account for within-subject correlation and, thus, would not be appropriate in this setting.

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The PISA radius derived from the M-mode (mm) was obtained by dividing the area between the first aliasing border and the valve leaflet leading edge during systole by the width of the area [6].

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The optimal multiuser receiver developed in [32][31] is based on the maximum likelihood sequence detection criteria.

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…isoforms (N-ter, R-233, PLCb136–87, D-8) recognized two bands with apparent molecular masses consistent with previous reports (Lee et al., 1987, 1993; Fukaya et al., 2008), whereas G-12 antibody only detected the heaviest band, in agreement with its expected specificity for the PLCb1a isoform (Fig.

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Additional rodent work investigating the effects of bilateral cortical lesions shortly following birth demonstrates a difficulty for early-cortical lesioned male, but not female, rodents to discriminate rapidly presented tones (<350 ms), while both sexes could reliably discriminate tones presented at longer interstimulus intervals (ISIs) (Herman et al., 1997).

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For example, male sex, unmarried status, poor premorbid functioning, a family history of mental illness, birth complications and urban residence have all been associated both earlier onset and more severe illness (Jablensky, 2000).

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AtVAD1 VASt domain 3D structure modeling and structure-based clustering The 3D structure of AtVAD1 (At1g02120) VASt domain (residues 257 to 449) was predicted with I-TASSER web server (http://zhanglab.ccmb.med.umich.edu/I-TASSER/).

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Anemone size reflects the size of the territory (Buston 2003a), and territory size could influence the fitness of breeders (Booth 1995; Beukers and Jones 1997).

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…‘LA1698’ and susceptible genotype ‘LA2683’
synthase (PaKCS6) (Khadivi-Khub 2015; Balbontı́n et al. 2014, 2013; Kasai et al. 2008; Huang et al. 2006; Lu et al. 2006; Wang et al. 2006; Moctezuma et al. 2003; Schuch et al. 1991; Peet 1992; Cuartero et al. 1981) have also been identified to be…

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In a follow-up experiment Pascalis et al. (2005) examined the plasticity of infants’ discrimination of monkey faces by providing 6-month-olds with folders containing pictures of six unfamiliar monkey faces where parents were asked to show these pictures to their infant for 1–2 min each day (see…

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However, it does not significantly affect the kinetic stabilities and dynamics of both topologies on the s time scale of the simulations (60).

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SIFT, RANSAC and Homography are well known algorithms and interested readers can refer to [110] and [111].

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AY9944 (trans-1,4 bis-(2-dichlorobenzylaminomethyl)cyclohexane dihydrochloride) (1 ŒºM as a working solution), N-acetylcysteine (NAC) and monodansylcadaverine (MDC) were from Sigma (St. Louis, MO).

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Shelf dataset: We use a full body model with 14 parts in this case as described in the original paper [4].

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As such, the analysis of aDNA has been greatly enabled by NGS (Green et al. 2010; Krause et al. 2010; Rasmussen et al. 2010; Meyer et al. 2012).

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At each quarterly follow-up visit, we conducted HIV and STI counseling and testing, treatment of curable STIs (as applicable), product adherence and risk reduction counseling and pregnancy testing.

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Immunofluorescence microscopy, colony and Western immunoblotting, and determination of switch frequencies were carried out using anti-α%$ antiserum in accordance with established procedures (Eisenstein, 1981; Caffrey et al., 1988; Henderson et al., 1997a).

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These properties of EGFR-targeted ILs are consistent with previous results obtained with HER2-targeted ILs, which indicated a similar threshold for HER2-overexpression (3, 4, 27).

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As can be seen, the temporal transition models provided by the HMMs result in about 5% performance gain in both state and environment tasks.

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Further investigation on the chemical constituents of the extract resulted in the isolation of eight new chromones (1–8) and three new phenol derivatives (9–11) together with eight known compounds: sydowinin A (12) [4], pinselin (13) [5], sydowinin B (14) [5,6], aspergillusone B (15) [7], AGI-B4 (16) [8], diorcinol (17) [9], cordyol C (18) [10], and hydroxysydonic acid (19) [11] (Figure 1).

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Findings of difficulties in locating the presented tactile stimuli, which were space- and not arm-based [32], and difficulties in deciding on the exact position and orientation of the limb or on the laterality of pictured hands in limb laterality recognition tests [29,42,48], are reminiscent of patients with poststroke

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Another method is locally linear metric adaptation (LLMA) [18], which is more general in that it is linear locally but nonlinear globally.

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There is a strong correlation between the progression of interstitial fibrosis and the progression of cystic disease [9,10].

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On the other hand, the studies have opened the operational HRN experiences through which providing the evidence-based inputs and facilities leads to predetermine supervised research outputs and outcomes (5-7).

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4). nlp-3 is expressed in many sensory neurons, including the ADFs, ASEs, ASHs, ASJs, and AWBs (Nathoo et al., 2001).

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The enhanced levels of ROMs production lead to DNA damage (Kindzelskii and Petty 2000).

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On the synonym choice task, we compute the accuracy of the covered items with partial credit for ties, following Mohammad et al. (2007). We report performance on all items as well as on the respective subset of covered items.

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The validity between the SNAP output and the Illumina Cardio-Metabochip product file was assessed using Cohen‚Äôs Kappa coefficient which calculates the percentage of agreement between both methods [9].

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AChE is required for endoderm adhesion to fibronectin
In vitro, AChE binds to extracellular matrix (ECM) ligands, promoting cell-
substrate adhesion (Johnson and Moore, 1999; Johnson and Moore, 2004; Johnson et al., 2008a).

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As defined in [11], a graph G is cliqueperfect if τC(H) = αC(H), for every induced subgraph H of G.

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However, Nam has a significant impact in the area consumption and in the node’s power consumption as detailed in [6].

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included demographic information (sex, age, ethnicity), drinking status, smoking status, and personal medical history (described in Whitcomb et al.(45)).

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In normalized form, these two eigenvalues provide a useful characterization of the global properties of the signal [33].

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As expected for a proline-rich glycoprotein, we have shown that these proteins contain various repeats of the decapeptide POVEKPOVYK and that the amino acid sequence of their amino terminal ends is the same, except for the fourth residue (García-Gómez et al. 2000).

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The promoter of S. elongatus glnN displays an imperfect NtcA-binding site (Aldehni & Forchhammer, 2006).

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One study has presented a daily average sedentary time of 9 h and 55 min (3 h and 10 min SD) [23].

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The study on the graft transmission of phloem proteins in interspecific and intergeneric heterografts in the Cucurbitaceae family suggested that the direction of phloem protein translocation depended on the scion/rootstock combination [43].

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These results are inconsistent with Se concentrations in individual tissues (Sevcikova et al. 2011), where groups supplemented with lactate-protein complex and Se-proteinate showed higher concentrations that groups supplemented with inorganic selenium.

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The C2 motif is suggested to be involved in the transcriptional repression by AtMYB4 and FaMYB1, containing the core sequence LXLXL, which is also part of the EAR repressor motif (Jin et al. 2000; Aharoni et al. 2001).

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In a meta-analysis, a majority of patients present initially with mild epigastric tenderness that leads to fever and tachycardia, then peritonitis after several hours [17].

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The measurement was performed in the sit-
 ting position with the arm held in a comfortable position as described by Spijkerman et al.29 Maximum strength was expressed in kilograms.

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Previous work has shown that such measures are related to dual tasking measures of gait variability (Springer et al. 2006; Yogev et al. 2005) and that they respond as expected to cognitive-enhancing pharmacologic therapy (Auriel et al.

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These results corroborate studies that have demonstrated an enhancement of other types of reward with Dz-specific agonists [6,17,21,52].

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This finding may account for the apparent persistence of previously unknown parasite strains in populations that are severely affected by HIV-1 (Pieniazek et al. 1999; Gramiccia, 2003; Pratlong et al. 2003).

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Both problems can be solved in polynomial time for strongly chordal graphs [6], comparability graphs [4] and Helly circular-arc graphs [7,11].

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The enzyme 3β-HSD has been localized in the ovary of a variety of mammalian species (Baillie et al., 1966; hamsters, Saidapur & Greenwald, 1978; humans, Sasano et al., 1990).

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Social ties can provide key resources necessary for individuals to perform the roles or tasks of daily living [22].

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The inability to shut off STAT signaling properly in anterior follicle cells enables an excessive number of cells to acquire invasive properties, which can impede border cell migration (Silver et al., 2005; Starz-Gaiano et al., 2008; Yoon et al., 2011; Monahan and Starz-Gaiano, 2013).

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with type 2 diabetes in recent years corresponds with results from several studies conducted in developed countries, including Canada [16], the UK [27], Denmark [11, 28], Australia [29] and the USA [30].

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The shape of this curve is also justified by the so-called S-curve of software testing [7, 4] that shows that the search

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The mean value of 0.46 obtained for the interclass Hamming distance distribution (see Figure 15b) is practically the same reported in the literature, in spite of the fact that a different iris image database
was used, indicating that the implementation of Daugman’s method used in this work presents coherent results.

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We chose this amplitude as it has been successfully used to elicit a female response in choice experiments (Hunt et al., 2005).

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Our results are consistent with those in mouse that show loss of mesodermal Fgf8a expression upon deletion of Tbx1 in the Mesp1-positive mesoderm (Zhang et al., 2006).

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The MPPD was applied to calculate the fraction of particles deposited and retained in specific parts of the human lung by comparing two different human exposure scenarios in the MASP.

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…(SNPs) compose the VZ while intermediate progenitor cells (IPCs) and basal radial glia (bRG), which are derived from VZ cells, populate the SVZ (Noctor et al., 2001; Gal et al., 2006; Kowalczyk et al., 2009; Fietz et al., 2010; Hansen et al., 2010; Shitamukai et al., 2011; Wang et al., 2011).

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…2005), poly (ethylene glycol) (PEG) (Law et al., 2004; Verheyen et al., 2002) and hydroxypropyl methylcellulose (HPMC) (Kushida and Gotoda, 2013; Miyazaki et al., 2011) or enteric polymers such as hydroxypropyl methylcellulose phthalate (HPMCP) (Miyazaki et al., 2011) and hydroxypropyl…

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We speculate that CL may be the result of the NHEJ-dependent fusion of uncapped telomeres and subsequent chromosomal non-disjunction, while IHR may be the result of the recombinational repair of replication lesions (Meyer and Bailis, 2007), or exonucleolytically digested chromosome ends (Hackett et al.

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Only the statistically powered NLST study, with a sample size of 53,454, has detected a 20% mortality reduction with low-dose CT screening over chest X-ray screening [5], which was why we simulated 100,000 participants to obtain robust results.

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Although predicting assay success rates based on the 50% duplication estimate of Allendorf & Thorgaard (1984) is subject to errors based on a large number of factors, our results are surprisingly consistent with their estimate.

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Results for multi-task GP We now investigate the merit of using MTL, using the trainingdata tabulated in Table 1 for loadsc1, . . . , c14.

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Third, for reachability query processing, we select seven state-of-the-art algorithms for comparison with our LORch algorithm, including GRAIL [30] (abbreviated as GRL3), FELINE [26] (abbreviated as FL), IP+ [27],4 PLL [29] , TF [5], BFL [21] and BFL+ [21].5 We test these reachability algorithms using both random and equal workloads, where each one contains 1,000,000 reachability queries.

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These correlation coefficients were then combined across all metaanalyses to obtain a summary correlation coefficient with a fixed effects model [13].

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…we identified 361 propionylation sites in 183 mid-exponential and late stationary phase proteins in Thermus thermophilus, an extremely thermophilic eubacterium (Okanishi et al. 2014), which was the first report showing the prevalence of post-translational lysine propionylation on diverse proteins.

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Conventional meta-analysis proceeds by conducting a separate meta-analysis for each type of treatment against all others [5].

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Another study reported improved knee function following conventional treatment and retro-walking program in individuals with knee OA [25].

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Procedures for animal management have been reported in our companion paper on the same animals [39].

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Two distinct steps define mitochondrial division - an initial constriction of mitochondrial membranes, followed by final membrane scission (Friedman et al., 2011; Korobova et al., 2013;Murley et al., 2013; Korobova et al., 2014).

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Asexual parasites of the 3D7 clone were grown and transfected as described previously (Dorin-Semblat et al., 2007).

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Nadolol, a nonselective Œ≤-blocker for the Œ≤1- and Œ≤2-AR, was selected because previous studies revealed this drug to be a full inverse agonist at the Œ≤2-AR (Bond et al. 1995; Wisler et al. 2007).

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While Karnani (2007) insightfully opined about the potential role of disempowerment in the demand for skin whitening creams, the focus of his research was to study the case of “Fair & Lovely”, a skin whitening cream marketed by Unilever in order to demonstrate that Fair & Lovely is indeed doing…

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Although these methods were initially introduced into language processing for classification tasks [106, 107] many different NLP fields have adopted this idea to reduce the cost of training.

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Haplotype definitions were adapted from the Pharmacogenomics Knowledge Base (PharmGKB) [1], while phenotype translations and clinical guidelines were taken from the Clinical Pharmacogenomics Implementation consortium (CPIC) [2], the Dutch Pharmacogenomics Working Group [3] or the American College of Rheumatology [4].

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In [10] and, the sliding-mode control technique was used for robot navigation and obstacle avoidance in an environment modeled with artificial potentials.

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Similar reductions in crested wheatgrass cover as a result of herbicide applications have been demonstrated in grasslands without patch burn grazing (Bakker et al., 1997; Hansen and Wilson, 2006; Wilson and Gerry, 1995; Wilson and Partel, 2003).

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To overcome this issue we start from pre-trained models that we obtain by training networks without Sparse Variational Dropout for several epochs.

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Nevertheless, the function of IL-27 on inhibition of IL-17 production by CD4+ T cells was substantial compromised in absence of STAT1 (21).

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Other categories might include ‘sex siren’, a category for masculine men who are judged for their sex appeal and physical attractiveness; ‘butch queen vogue’, a category that uses elements of vogue of hands, spins and dips; ‘femme queen’, and ‘virgin runway’, a category that is open to participants who are relatively new to the Ball scene (Dickson-Gomez et al., 2014; Galindo, 2013).

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Antidepressant use during follow-up was associated with more frequent mood episodes [436].

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…for multivariate analyses and experimental manipulations
Within groups of A. percula, the size of the largest individual influences group size (Buston 2003b), group size correlates with anemone size (Fautin 1992), and anemone size correlates with the size of the largest individual (Fautin…

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We modified the implementation of Virpioja et al. (2013) to remove the previous segments of the word from the parameters before reanalyzing the word, and re-adding the segments of the new optimal segmentation afterwards.

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As an example, we investigate the 27 nt pseudoknot PK1 of the upstream pseudoknot domain of the 3’-UTR of tobacco mild green mosaic virus, pseudobase ID PKB92 (Leathers et al., 1993).

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TSSs of HERG1b, KCNQ1a, and KCNQ1b genes were determined with Ambion’s RNA-Ready cDNA Human Heart RNA Ligase-Mediated Rapid Amplification of cDNA Ends (5 -RACE) kit, as previously described (15).

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Comparative proteomics profiling of the attenuated line identified key changes in parasite thiol-redox metabolism [15].

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Akin to dispersive Fourier transform spectroscopy (29), free-induction decay s-SNOM (15), and nano-FTIR (17, 20), we use an asymmetric Michelson interferometer to frequency resolve the scattered near-field signal and amplify the weak, tip-scattered light.

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Nevertheless, the high sequence similarity, overlapping expression domains, and similarities in dimerization partners (Immink et al., 2003) of a number of petunia MADS box genes, especially among members of the same subfamily, suggest that genetic redundancy may be the major cause of the lack of…

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All typical features of SDR (Oppermann et al. 2003) were found in the obtained model (Fig.

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In the rat kidney, carrier-mediated urate transport is reported to be operational in the proximal tubule based on microperfusion studies (Sansom et al. 1981; Weinman et al. 1983).

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A previously described computerized force-sensitive system was used to quantify gait cycle timing, specifically the swing time and the stride-to-stride variability of swing time (Yogev et al. 2005; Bazner et al. 2000; Frenkel-Toledo et al. 2005).

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For the dose–response analysis, we used GLST command in Stata software as the method proposed by Greenland and Longnecker [30] and Orsini et al.

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