In mammalian cells, cyclin D–CDK4/6 and cyclin E–CDK2 complexes are required to promote cell cycle entrance from quiescence, progression through the G1 phase and transition from G1 into S phase in response tomitogenic stimulation (Sherr, 1995; Malumbres and Barbacid, 2001; Chulu and Liu, 2009).

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In fact, their basis are MP grammars, where multiset transformations are regulated by functions in a deterministic way [19].

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Bone from McCune-Albright syndrome patients shows a fibrous infiltrate, significant increases in trabecular bone formation, ablation of the marrow cavity, and an increased propensity to deformation and fracture [35].

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Thus, while the current study reproduces the spectral EEG changes induced by propofol in more detail than (Hutt and Longtin, 2010) which did not focus on reproducing spectral EEG peaks themselves, but instead on bi-phasic power changes, it is limited to the first phase of the bi-phasic response.

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TfMA had lower sequence identity of 33~27% with α-amylase II from Thermoactinomyces vulgaris (Tonozuka et al. 1993), maltogenic amylase from Thermus sp. IM6501 (Kim et al. 1999), neopullulanase from Geobacillus stearothermophilus (Cheong et al. 2002), glucosidase from Thermotoga maritima (Lee et…

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It has proven a suitable method for determining the content of a CPT curriculum.(14,15,17) The modified Delphi process took place between January and July 2017 and comprised the following: a systematic literature search; selection of a European expert panel; and development of a Web-based questionnaire and its modification in two consecutive rounds followed by a face-to-face meeting and final round.

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Others implicitly set γ ≡ 0 to investigate the relationship between damages and socioeconomic vulnerability; see Kellenberg and Mobarak (2008), Bakkensen (2013), Bakkensen and Mendelsohn (2016) and Geiger et al. (2016).

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…have been based on unselected populations of animals although it might be more productive to study this issue in animals that show an innate predisposition to express high or low levels of anxiety
18 Introduction
(Brush, 2003; Landgraf & Wigger, 2002; Lister, 1990; Steimer & Driscoll, 2003).

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subtilis perRBS mutant, the expression level of fur is known to be less than one-third of those of katA, mrgA, and ahpC (Fuangthong et al., 2002; Faulkner et al., 2012).

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Immunoprecipitation and western blot Protein extraction, western blots and immunoprecipitations were performed as previously described (Pentimalli et al., 2008).

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The high concentration of Ca activates mitochondrial calcium-sensitive K channels (mtKca) and mitochondrial nitric oxide synthase (mtNOS), which increases the levels of nitric oxide (NO) (Figure 3) [21, 23, 33, 64, 100, 101, 107–115].

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Responses of several NTD models to various nutrients have been tested, with some showing responsiveness and others resistance to supplementation or to deprivation [21-26,28,34].

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Moreover, a resting state functional connectivity analysis showed that the TPJa and TPJp are embedded in different functional networks: the right TPJa activity interacted with the bilateral IPL, the ventral prefrontal network, and the anterior insula, which are often associated with ventral attention network [41,44], while the right TPJp interacted with the posterior cingulate, the temporal pole, and the anterior medial prefrontal cortex, which are often implicated in social cognition [45].

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Moreover, still others have reported that the selective inhibition of Ang-2 activity promotes blood reperfusion following ischaemia through the recruitment of inflammatory cells and combination with VEGF [5, 9].

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ATP7A and ATP7B are P1B-type ATPases, which use the energy released from ATP hydrolysis to transport Cu across Golgi membranes (Jayakanthan et al. 2017; Lutsenko et al. 2008; Yatsunyk and Rosenzweig 2007; Yu et al. 2017b).

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The cluster goodness can be additionally evaluated through measuring the purity, entropy and F-Measure [23, 24, 25].

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According with our previous results (Orihuela & Croxatto 2001, Orihuela et al. 2001, 2003) and those shown in this paper we propose a model indicating that the nongenomic pathway utilised by E2 to accelerate oviductal transport of oocytes in cycling rats involves successive activation of the…

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These studies have generally found that cells from immature ventricles, compared with adult myocytes, display 1) a reduction in the density of outward K currents (28, 51), 2) greater activity and expression of Na /Ca(2) exchange (NCX) (2), and 3) intracellular Ca(2) transients that depend less on sarcoplasmic reticulum (SR) Ca(2) release and more on transmembrane Ca(2) influx (21, 32).

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Amino acid residues involved in the iron binding site of dioxygenases (Britsch et al., 1993) are conserved in the above-mentioned dioxygenases (asterisks in Figure 3).

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Mechanistically, gametic and somatic DMRs both require the maintenance of DNA methylation by DNMT1 (Caspary et al., 1998; Bhogal et al., 2004).

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The first experiment was purposed for foreign language education (Kanda et al., 2004 d), but there was no mechanism for long-term interaction implemented in Robovie.

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The caeca of chicks are the intestinal organs that contain the highest loads of the bacterium (Beery et al.,
1988; Hendrixson and DiRita, 2004).

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NP3L [10] is consistently outperformed by our methods, while for UPnP [8] our NPnLupC outperforms it in the noisy cases.

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Indeed, in response to dual tasking, patients with PD and idiopathic fallers walk more slowly and reduce their average swing times (Springer et al. 2006; Yogev et al. 2005).

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As a covariate, the effect of exercise on parameters was examined both as a two-point proportional effect between the two levels of high intensity and the lesser prolonged intensity [2–4] and also as a single additive effect.

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1http://owl.man.ac.uk/factplusplus 2http://kaon2.semanticweb.org/
 The meta-data is generated by code written for SWOOP [9], and provides the details of the expressivity (i.e. the constructs present in the ontology) together with the number of classes, object properties, data properties, individuals, class axioms, property axioms and individual axioms present.

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The variables selected for the regression analyses were those that correlated significantly with serum FGF21 or FFAs and those that have been shown to be associated with plasma levels of these proteins [4,9].

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In rare cases where PCR did not yield amplicons, the primers 63f (50 CAG GCC TAA CAC ATG CAA GTC 30) and 1387r (50 GGG CGG WGT GTA CAA GGC 30) (Marchesi et al. 1998) were used.

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Proposed approach is compared with supervised variable selection methods: maximum mutual information minimal redundancy (MIMR) method [18] and HITTON_PC and HITTON_MB [19] methods.

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We obtained 658–667 bp of mtDNA control region sequences for each species from published data sets (Kulikova et al. 2005, 2012; Peters et al. 2005, 2008, 2012b, 2014; Lavretsky et al. 2014; Table S3, Supporting information), supplementing these data with new sequences.

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Only 15% cases undergoing cataract surgery in 1995 had IOL implantation while almost 90% of cases had IOL implantation in 2006 [24, 38].

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There is a significant increase in the levels of cariogenic bacteria in the saliva and plaque of patients undergoing fixed appliance treatment.(21,22) However, during the initial phase of caries growth, S mutans is the most frequently associated microorganism.

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These clusters of informative voxels, along with a cluster implicating the occipital cortex, have also been consistently found in neuroimaging studies using statistical parametric mapping (Bush et al., 2000; Colibazzi et al., 2010; Gerber et al., 2008; Hagan et al., 2009; Killgore and Yurgelun-Todd, 2004; Narumoto et al., 2001; Posner et al., 2009; Robins et al., 2009; Wager et al., 2008).

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…in the dependability definition (see Section 2.4 below), the attribute safety, since it is also included in the dependability definitions seen in Section 1, is directly included in the definition (see (Rüdiger et al., 2007a) for a definition of the remaining attributes in a behavioral context).

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Hence, with the understanding that measuring instruments need to be used by physical therapists in order to objectively quantify alterations affecting mainly the thoracic and lumbar regions of the spine, and to establish the criteria for planning and following up their interventions13, the aims of the present study are to investigate (1) the accuracy of the angles of the sagittal curvature from the thoracic and lumbar regions of the spine obtained using an instrument adapted from the arcometer developed by D’Osualdo, Schierano and Iannis18 by comparing them with those obtained using X-ray examination and (2) the inter-evaluator reproducibility and the intraevaluator reproducibility of the arcometer.

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Ectopic activation of Hedgehog activity in PDCs was obtained either through expression of a dominant-active version of GLI2 [41] or a dominant-active form of Smoothened (SmoA1).

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Such training has been shown to reduce resting CRP and IL-6 (Mendham et al. 2014), and improve glycaemic control (Andersen et al. 2014) and body
composition (Andersen et al. 2010).

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(Massie and Holland, 1984; Ciaramella and Poli, 2001; Uchitomi et al., 2003; Katz et al., 2004; Ell et al., 2005; Boyd et al., 2012; Kim et al., 2012; Mitchell et al., 2012; Palmer et al., 2012; Pirl et al., 2012; Tada et al., 2012; Warmenhoven et al., 2012; Yu et al., 2012).

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We ultimately selected a 2007 study using Medicare Advantage data to estimate the direct medical costs attributable to CVD events [26], and a 2002 Canadian study to determine age-specific productivity losses due to events [30].

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In the ISO standard (Bunt et al., 2012), FSs can theoretically be discontinuous or run across turn boundaries.

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In crustacean, apart from functioning as a digestive gland, hepatopancreas is also an important immune organ that functions as a primary site to synthesize and excrete immune molecules, such as beta-1,3-glucan binding protein (LGBP) [16], antibacterial peptide (AMP) [17], lectin or lectin related proteins and others [18].

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…showed that imaging or therapeutic agents larger than the BBB’s exclusion threshold of 400 Da could be successfully delivered by FUS with microbubbles (Alonso et al. 2013; Choi et al. 2007; Choi et al. 2010a; Hynynen et al. 2001; Kinoshita et al. 2006; Marquet et al. 2014; Shen et al. 2014).

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Ramirez et al. (2015) reported a lower LOD, thus higher analytical sensitivity, of kDNA PCR compared to Sat-DNA PCR tests for T. cruzi VI.

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[24] showed that, for this choice of joint feature vector, loss-augmented inference can be performed optimally using an efficient greedy algorithm.

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SEQUENCE KBT [10] PPM [15] LBPT [20] KCF [9] Proposed Average success rate 164 100 88 165 66

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We undertook the present study because recent availability of new fibroblast markers has reduced the difficulty in addressing this issue (7, 8).

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In addition, the P-VS profiles of SA1 and SA2 have only one inflection point, at the onset of the average Si-O coordination number’s increase from 6 to 6+ (Brazhkin et al. 2011; Wu et al. 2012; Murakami and Bass 2010, 2011).

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at least 60–85%) fasting triglycerides, in agreement with previous data obtained in healthy subjects (15, 39).

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These results are in keeping with previous research investigating the processing of kana and alphabetic languages (Bolger et al., 2005; Ischebeck et al., 2004; Nakamura et al., 2005; Sakurai et al., 1993, 2000; Tan et al., 2005a; Thuy et al., 2004), as well as kanji and logographic languages…

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We compare our results with regular Gibbs sampling (Gibbs) and the approach proposed in Venugopal and Gogate [30] (cgibbs), where they use clustering algorithms such as KMeans to derive an approximate MLN and then sample this MLN using regular Gibbs sampling.

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Previous comparisons of transcriptome content [10], gene expression patterns [11-13], and gene function [14,15] between Amborella and other flowering plant species have suggested that much of the floral development program that has been characterized in Arabidopsis, snapdragon and maize existed in the last common ancestor of extant angiosperms.

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Treatment options include surgical excision, chemotherapy, immunotherapy with rituximab for patients with positive CD 20 immunohistochemistry, or radiosurgery.(1-30) For patients without systemic involvement, external beam radiotherapy (EBRT) is often used after histopathologic confirmation.

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For this analysis we use the two SI distributions observed from investigations of the first 100 pH1N1 cases in South Africa [22]: (1) the SI distribution between primary cases and laboratoryconfirmed secondary cases only (39%, 24%, 14%, 17%, 3% and 3% for day 1 to 6 respectively), and (2) the SI distribution between primary cases and suspected plus laboratory-confirmed secondary cases (30%, 17%, 20%, 23%, 7% and 3% for day 1 to 6 respectively).

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DAA cases were performed with a slight modification of the technique described by Lovell [15], with anterior capsulotomy and subsequent repair, the use of a standard operating table with a table mounted femoral elevator (Omni-Tract Surgical, St. Paul, Minnesota), selective soft tissue releases based on the mobility of the femur (conjoined tendon was released in most cases and piriformis was released in some), and the use of fluoroscopy in every case for assessing component positioning and limb-lengths.

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With data from the Southwest Oncology Group (SWOG 8794) for the use of adjuvant radiation therapy in high-risk patients (21), and Messing trial results demonstrating an advantage in survival for long-term ADT in lymph node-positive patients (22), good pathologic data are an important step toward multi-modality approach.

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Internal consistency for the PIWSUR total score were reported to be excellent by (Burns et al. 1996) (Cronbach’s alpha = 0.92), and for the subscales was fair to good with alphas ranging from 0.77 to 0.88.

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Two PTF1 binding sites are present in the 2.3 kb Ptf1a regulatory sequence Sequence analysis of the two highly conserved peaks in the 2.3 kb enhancer revealed the presence of two PTF1 binding sites, referred to here as the proximal (P) and the distal (D) PTF1 sites (Masui et al., 2008).

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Then we make quantitative comparisons with other state-of-the-art approaches on the 5-class and 6-class collective datasets, including RSTV approach in [7], a joint tracking and recognition flow model in [15], a complex hierarchical model in [5], a bayesian BORD method in [1] and a discriminative latent model in [17].

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FISH was carried out according to Pinkel et al. (1986)
using 5S rDNA probes obtained by PCR from Prochilodus genomic DNA using the primers A (5_-TACGCCCGATCTCG TCCGATC-3_) and B (5_-CAGGCTGGTATGGCCGTAAGC-3_) (Pendás et al., 1994).

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Studies on HA have shown previously that HA have the ability to decrease respiratory stress, and reduce hyperactivity in eastern rainbowfish fingerlings exposed to low pH during 96 h exposures (Holland et al., 2014a).

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8-kb genomic fragment containing all of the noncoding exons demonstrated tissue-specific expression in transgenic mice (Drews et al. 2005).

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A similar behaviour was found in the context of Higgs production in association with bottom quarks [31].

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Previous research find that the VOT value of aspirated decreases and overlaps with that of lenis for younger speakers, but not for older speakers (Jin 2008, Kang 2014, Kang and Guion 2008, Silva 2006, Wright 2007).

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The developmental changes associated with puberty, pregnancy, lactation and involution of the mammary gland have been extensively studied and signaling pathways initiated by both membrane and nuclear receptors are essential for coordination of these events [1].

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Many estimation processes applies the probabilistic approach to determine the state of environment because of the uncertainties of measurements [12,15].

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Figures 3 and 4 present in silico plasma profiles from the final, validated analog under fasting and fed conditions, respectively, shown with the GITT model predictions from [17].

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…and often impossible task (see, e.g., Herrmann et al., 1990; Saunders et al., 1992; Anderson et al., 2010; Franklin, 2010), and stature estimations may vary largely depending on the applied method (see, e.g., Sciulli et al., 1990; Raxter et al., 2007; Siegmund, 2010; Carretero et al., 2012).

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MEDLINE), one can find the elements of the PICO structure, but rarely explicitly annotated (Dawes et al., 2007).

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The pulvinar and much of the thalamus are centres of high-order (cortical to cortical) relay connections and their activation in early hypoglycemia may reflect arousal-enhanced relay of integrated sensory information to other cortical areas (reviewed by Sherman, 2007).

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…Screen / Esc
Printer-friendly Version
Interactive Discussion
D iscussion P aper
| D iscussion P aper |
D iscussion P aper
| D iscussion P aper |
Ocean is unphysical, and subtract it from each along-track row; this approach is similar to those applied in previous studies (Boersma et al., 2007).

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Native Skp1 sequences were employed because a previous study showed that N- or C-terminal peptide tags interfere with its hydroxylation and activity in cells [10].

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capillary endothelial cells [16;17] - we have been evaluating its participation in the response to respiratory tract infections.

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We took inspiration from previous research done in the context of novel IDEs ([15], [16] and [17]) and used abstraction to present a concise view of the entities of a software model.

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The settings for the Maras’ and Fan’s strategies shown in Table 1 are consistent with those in their original studies of [4] and [7].

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vinifera (P28343, Coutos-Thevenot et al., 2001; Giorcelli et al., 2004; Zhu et al., 2004) that have been successfully used in gene transfer experiments.

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the thoracic and lumbar curvatures: (1) X-ray examination from which the Cobb angles (CA) of both curvatures were obtained, and (2)

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…with 675 kHz scanning pencil beam sonar and a 200 kHz multibeam sonar for near-bottom bathymetric surveys, both with vertical resolution as high as centimeters to decimeters depending on acquisition parameters [Singh et al., 2000; Whitcomb et al., 2000; Roman et al., 2005; Ferrini et al., 2005b].

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Substance P is involved in several behavioral processes, such as reinforcement, learning, memory, and pain (28-31).

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For example, it is found that individuals with ASD tend to under report the severity of their autistic features (Johnson, Filliter, & Murphy, 2009) and show diminished awareness of their mental states (Williams & Happé, 2009, 2010).

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Indeed, the non-monotonic reasoning community has continuosly produced, in the past, several extensions of nonmonotonic logic languages, aimed at improving readability and easy programming through the introduction of new constructs, employed in order to specify classes of constraints, search spaces, data structures, new forms of reasoning, new special predicates [2, 9, 18], such as aggregate predicates [4].

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…a high correlation with the medial temporal lobe, by means of atrophy
224 Chapter I
(Diamond et al., 2007; Sánchez-Benavides et al., 2010, 2014; Sarazin et al., 2010; Wenger, Negash, Petsersen, & Petersen, 2011), hypoperfusion (Habert et al., 2011) and hypometabolism (Van Der Gucht et al.,…

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The model (Rohrer and Berresheim, 2006; Hofzumahaus et al., 2009) was based on the Regional Atmospheric Chemical Mechanism (RACM) (Stockwell et al.

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NO has been shown to contribute to host defense against intracellular pathogenic microorganisms such as Salmonella [35,36] and to inhibit virus proliferation [36,37].

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…succinylation (Zhang et al. 2011; Park et al. 2013; Weinert et al. 2013b) in organisms from humans to bacteria, malonylation (Peng et al. 2011) and glutarylation (Tan et al. 2014) in eukaryotes, and propionylation in bacteria (Okanishi et al. 2014) were recently revealed as prevalent PTMs.

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However, at temperatures above 20uC, the strong selfassociation propensity of human IAPP rapidly drives monomeric IAPP molecules toward oligo- and multimerization [24–27].

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Electron Microscopy and Immunolabeling
Arabidopsis embryos and root tips and tobacco BY2 cells were highpressure frozen/freeze-substituted for electron microscopy analysis as described previously (Otegui et al., 2002).

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However, these analyses were undertaken prior to obtaining results from the MENTOR study and used the NICE guidelines [7] threshold for treating with a biologic rather than the BSR guidelines [10].

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Betrachtet man die Programmiersprache Java [53], so stellen beispielsweise Klammern statische Tokens dar, während die sogenannten Modifikatoren von Methoden und Feldern (public, private und protected) semantisch und somit variabel sind.

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This phenotype is reminiscent of the phenotype observed in Arabidopsis plants expressing Hahb-4, a drought-inducible HD-Zip family I gene from sunflower that was implicated in ethylene-mediated control of senescence (Manavella et al. 2006).

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Following Baker et al. (2012), I include a constant and a linear time trend in xt.

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Such an intervention would be important because little or no vaccine would be available against the first wave of pandemic influenza (Longini et al., 1978, 2004).

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Statistical analysis of EEG SSDC as applied to the frontal–central and parietooccipital cortical areas also confirmed the previously demonstrated [2] zonal speci ficity of SSDC in the MM–REO and RM–REO con trasts.

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The sensation evoked by CO2 was stinging or burning pain, as has been reported in other studies.(17,18,19,20) The putative neuronal substrate for this is polymodal nociceptors or chemonociceptors.

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analysis was limited to patients with methicillin-resistant isolates only.(3) In con-

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This is consistent with many studies that have demonstrated that increased fibrosis results in greater impairment in functionality (14, 45-48).

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The distribution of initial radon levels in the series of 65 houses is shown in Figure 2 , and this has the same pattern as reported by Denman and Phillips (1998a).

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Certainly, patients may exhibit leakage on angiography (for example leakingmicroaneurysms in diabetic retinopathy), but no fluid accumulation within or below the retina as a result of compensatory removal of fluid by the retinal pigment epithelium (RPE) [14].

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Although lots of works have reported that these features could be used to obtain accurate results in human detection, they encountered many difficulties in perceiving the shapes of human objects with articulated poses and cluttered background [10,11].

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Besides that, no ameliorate impacts have been obtained on the use of antioxidants in some studies (12,13).

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Finally, actin-capping protein was found to regulate actin polymerization at autophagosomes downstream of PI(3)P synthesis (Mi et al., 2015).

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%) and in the Registro
 Informatizado de la Enfermedad TromboEmboÃÅlica (RIETE) (major bleeding at 3 months: 3.4% vs. VTE recurrence at 3 months: 2.1%).16 Similar results were also observed in the Worcester Venous Thromboembolism Study.11
 The main strength of our study is the multicentric prospective inclusion of unselected VTE patients in a real-world setting that provides a representative picture of the age distribution in patients with acute VTE.

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Similar results were also obtained by Harris (1978) and Tamiru (2005) for potato, Onwueme (1978) for yam and (Mulugeta, 2007) for taro.

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For each target force, the vertical sensitivity of the oscilloscope was adjusted so that the target line would remain 16 cm up the screen (39,40,46).

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The real-world spaces that surround information users have been diversely called everything from personal information environments (Kwasnik, 1991; Malone, 1983) to personal information management (PIM) systems (Barreau, 1995) and personal spaces of information (Jones, 2007). Drawing upon interviews with academics, Lee (2003) proposes a model of three concentric zones of information that surround a user: “immediate,” within arm’s reach or a few footsteps away; “adjacent,” such as a nearby university library; and “outside,” such as a more distant bookstore. Speaking largely from an objectifying stance and adopting Lee’s concept of the “immediate information space,” this paper focuses on a visual research method—photography— that seems particularly well suited to learning more about settings and their accompanying information phenomena. A variety of investigative approaches may be used to study immediate information space. Jones (2007) suggests ethnography combined with design methodologies, and places emphasis on context and situation, including contextual inquiry (Beyer & Holtzblatt, 1998), situated activity (Suchman, 1983), and situated design (Greenbaum & Kyng, 1991). Naumer and Fisher (2007) recommend naturalistic inquiry (Lincoln & Guba, 1985) and the data-gathering methods of unobtrusive observation, interviews, diaries, text analysis, pictures, and videos.

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More suitable analyses have therefore been proposed, including growth curve analysis (Magnuson et al. 2007) and mixed-effects (logistic) regression (Barr 2008; Huettig et al. 2011).

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Similar results have been reported by others (Tassou et al., 1995; Del Campo et al., 2000; Skandamis and Nychas, 2000).

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V1 was identified as a largely acallosal region ( 1.5 mm wide, 2 mm long) on the medial side of a callosally connected rostrocaudal band (Wang et al., 2007).

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Network dimensions showing the number of connections per neuron and the radius in the preceding layer from which 67% are received
the order of 100 spikes ⁄ s in the visual system (Rolls & Deco, 2002; Rolls, 2008b).

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Previous studies indicate that both the age and the disease duration have an influence on the progression of MS [3, 19].

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Pneumolysin interaction with TLR4 on epithelial cells induces ERK-mediated production of MUC5A mucin, potentially enhancing trapping of bacteria in mucus and further enabling clearance [99].

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Based on their ability to monitor the dielectric characteristics of the surroundings separately from hydrogen bonding [18], several 3HC-based probes were designed to quantify the local water concentration at selected positions of biomolecules [17], opening new possibilities in the investigation of biomolecular interactions [19, 20].

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*Author for correspondence (wallingford@austin.utexas.edu)
D E V E LO
P M
E N T
sufficient to disrupt core PCP asymmetry and result in a loss or reversal of structural polarity (Adler et al., 2000; Bastock et al., 2003; Strutt and Strutt, 2007; Tree et al., 2002).

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polyps are mainly distributed on artificial constructions off the coasts of Japan, the UK, France and the Mediterranean (Miyake et al., 2002; Ishii & Katsukoshi, 2010; Duarte et al., 2012; Malej et al., 2012; Marques et al., 2015; Vodopivec et al., 2017).

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Traditionally, analytical placement has been formulated as a mathematical program with either linear or quadratic wirelength objective function [15, 30, 34, 8, 17, 64, 43].

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Moreover, there is increasing evidence suggesting that MP may protect against age-related maculopathy [2].

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Cre F1 mice underwent a surgical procedure to create unilateral ureteral obstruction (UUO) producing experimental renal fibrosis in one kidney (8, 30).

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A recent in vitro study with MBD1-6 reported that MBD1-3 was compacted without Cu and adopted an extended conformation after Cu loading (Yu et al. 2017b), indicating a possible impact of Cu binding on the structural arrangements of both linkers and MBDs.

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…3 s were trimmed from each time series to eliminate transients. the remaining data were analyzed using crossrecurrence quantification analysis (cRQa; Marwan et al. 2002; shockley 2005; shockley et al. 2002; Webber and Zbilut 2005; Zbilut et al. 1998) to measure interpersonal coordination (of…

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We reimplemented two of the baselines given on the Letor webpage:
RankSVM Our own implementation of RankSVM achieves better results than the
Letor baseline.

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China’s role in Apple’s global supply chain (e.g., Linden et al., 2009; Dedrick et al., 2010) have received a great deal of attention.

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Bivariate analysis of CD133 and nuclear beta-catenin was reported to be associated with decreased survival of patients due to ominous course of IIA colonic adenocarcinomas with coexpression of these both markers [24].

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[23] stated that infection, either major or minor, is listed as the cause of DKA in 15% to 50% of the cases.

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The new reference models result in slightly larger predicted values than previously used Viljanen values especially in males, but significantly lower values than the ECSC predictions in females.

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Although other studies have also demonstrated these findings (2,9,21), these results are contrary to more recent reports published from other institutions and joint registries which suggest functional outcome is inferior to that following primary TKR, with suggestion that it is actually similar to that following revision of a primary TKR at six-months (3,15,19,24).

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The second dataset contains the expression data of genes in 63 plant tissues that were generated within the framework of the AtGenExpress project (Additional data file 2) [39].

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To compare acute reduction of hERG surface protein to a well-characterized inhibitor of hERG forward trafficking, pentamidine, a chemiluminescence assay was used (Kuryshev et al. 2005; Wible et al. 2005).

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Also we show that the H-Ras mutant C181S creates the highest amount of rasosomes relative to the other palmitoylated Ras proteins, this complements the recent results which shows that this mutant has the lowest tendency to be solubilized by PDE6d.18 Hence, rasosomes can act as an alternative mode for transfer of hydrophobic Ras that cannot be carried by PDE6d.

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The main effector cytokine of Th17 is IL-17; other cytokines are IL-22, IL-26, and GM-CSF [52–56].

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The Hospital Anxiety and Depression Scale (HADS) is a self-completed 14-item screening questionnaire on a 4-point scale (Snaith and Zigmond, 1986), and was used to grade the severity of neuropsychiatric symptoms.

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fMRI studies using motor tasks in children with CP-U demonstrated abnormal pattern of activation, which included reduced activation in the affected hemisphere and existence of ipsilateral activation (Guzzetta et al. 2007; Sutcliffe et al. 2007, 2009; You et al. 2005).

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Gene ontology analysis was conducted using DAVID [8] and p-values was adjusted using the Storey q-test [15].

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For HFrEF, the INTERMACS profile score (15) has proven invaluable in capturing a patient’s prevailing health status and facilitating risk/benefit assessment.

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This leads to the formation of a knickzone, where a slowly eroding plateau with smooth hillslopes is juxtaposed to a rapidly eroding reach with elevated channel steepness, high erosion rates, and steep hillslopes (Safran et al. 2005; Blodgett and Isacks 2007).

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The growth inhibition effect of TGF-ß is mediated by its receptor, especia11y type I [78], with the p53 gene not likely participating in the process [77].

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Also, some approaches reduce the access time by caching [2, 3, 7, 18, 33], and nonuniform broadcasting [3, 18, 30, 31], and some reduce the tuning time by indexing [14, 19-21, 29, 33, 35], hashing [19] or using signature [24] techniques, where the tuning time is the amount of time spent by a client listening to the channel.

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The NMR structure of CD [9] has revealed a globular shape made of a three-stranded anti-parallel b-sheet packed against a Cterminal a-helix.

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Five of the seven studies showed a significant difference (p < 0.05) in favour of microTESE (Amer et al., 2000; Okada et al., 2002; Ramasamy et al., 2005; Colpi et al., 2009; Ghalayini et al., 2011).

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These data are consistent with the previously demonstrated defect of ubc9-1 mutants in the degradation of Clb2 and Clb5 (Seufert et al., 1995).

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Discrepancies analogous to those between our results and those of simulations have, indeed, recently been observed in the case of the binary perceptron [18], the pspin interaction spin glass [19], and in the case of fluctuating manifolds in random media [20], where dynamically frozen phases were observed in regions of parameter space in which static approaches yielded ergodic phases.

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The clustering method implemented in tbESTdb is based on the phred/phrap algorithms [23] and ensures high discriminatory power to identify closely related paralogues and distinct gene copies [22].

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In NSCLC, common PTPRB downregulation was associated with worse overall survival (197), whereas PTPRD downregulation and mutations were associated with worse

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In accordance with this assumption, considering the different experiment results in literature [12] [11] [14], the first step of a domain independent extraction process is the elicitation of these concepts, which is carried out with the help of an algorithm using the wikipedia category system.

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6245, which was reported to be associated with a specificity of 90% (Wolfe et al., 2010), was used.

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To calculate the density of the target receptor more precisely, the background intensity of the film was subtracted from the intensity within ROI, following a previously established computation (Suzuki et al., 2010a, 2010b).

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6, WAT endothelial cells and ASCs increased local breast cancer growth in 2 different models of orthotopic breast cancer (5).

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There have been also many interesting attempts to construct a consistent mathematical representation for polarization optics based on the Lorentz group [7]–[13].

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Model I-2 (n = 4) and -5 (n = 4) were directly injected with 50 mg of the human AE1-targeted siRNAexpressing vector and 50 mg of the scramble vector into the tail vein, respectively, once every 3 days for a total of seven doses, as described previously (Garg et al., 2008).

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PL, an electrophilic small molecule identified in cell-based, high-throughput screening assays was shown to selectively kill cancer cells without harming the normal epithelial cells (3).

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‚Ä¶expatriate partner adjustment: we interpret this result a similar fashion than the findings and remarks of some authors (Shaffer and Harrison 2001; Cole 2012) who stated that expatriate partners that decided to interrupt their career in order to follow their partner in the international‚Ä¶

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Davison et al. (2008), in a wide review of studies about this subject, pointed to inconclusive results.

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Neuroimaging studies and event-related brain potential research have established that the ACC is central to performance monitoring (Carter et al., 1998; Gehring and Knight, 2000; Luu et al., 2000; Ullsperger and Von Cramon, 2003).

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Since Ascent dehumanization is more closely related to animalistic (vs. mechanistic) dehumanization (Kteily et al., 2015, Study 5), we excluded these items from our blatant dehumanization composite.

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High BP induces structural and functional alterations, mainly in the form of left atrial enlargement.(7) Therefore, left atrial size is a recognized risk factor for AF and stroke.

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These experiments are described in detail elsewhere (Oum et al., 1998; Knipping et al., 2000; Hunt et al., 2004).

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While this method is known to be generally reliable, there are some questions about the representativeness of the data used [25].

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The depth and length of MBs may be responsible for the severity of these conditions (Canyigit et al. 2009; Ferreira et al. 1991; Lazoura et al. 2010; Ozbag and Kervancioglu 2004; Santos et al. 2007).

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Our results are consistent with the other studies that find a deficit in contralateral feature search (Riddoch and Humphreys, 1983; Eglin et al., 1989; Pavlovskaya et al., 2002).

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Streptomyces isolates (n=269) were characterized for antibiotic inhibition profiles by evaluating their ability to inhibit each standard isolate using an agar-overlay method (Davelos et al., 2004a).

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These results differ from a previous canine ACHMmissense mutation, CNGB3-D262N, located in the S2 transmembrane segment of CNGB3 [24, 51].

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) (Burdette and Whitaker, 2005; Carver et al., 2008; Ding et al., 2011; Gomez et al., 2004; Molnar et al., 2004; Mota et al., 2005).

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It has been employed more formally by other scholars in the library and information science (LIS) field to decompose the particulars of notions like “information” [4], in the development of ontologies [12], and for the development of conceptual frameworks for metadata schema [5].

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A scoping review using the methodology described by Arksey and O‚ÄôMalley [18], and refined by both Levac et al. [19], and Colquhoun et al. [20] will be used to address the research question.

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An alternative is to fuse the information from multiple cameras surrounding the vehicle [29] and such methods have been used to fuse between a forward-facing camera and LIDAR [10,27].

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1 expression are induced by seizures in experimental models (present results; for review see [1,57,61]), we cannot exclude that seizure activity may contribute to their level of expression.

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In view that PFD changes mouse liver glutathione S-transferase (mGST), glyceraldehyde-3-phosphate dehydrogenase, carbonic anhydrase III and Zn superoxide dismutase (CuZn-SOD) contents [42, 47, 48], we wished to explore whether it affects other cellular antioxidative enzymes.

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intrauterine pregnancy.(9) We present this data in aggregate and by physician to better represent individual variation in ability to identify an intrauterine pregnancy.

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This occupational social class measure has been previously used to investigate socioeconomic inequalities in mortality, cardiovascular disease, disability, and trends in inequalities in all-cause and coronary disease in this cohort [18,22,23], and other studies [24-28].

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They posited that trans acting differences tend to generate intra-
specific expression polymorphisms (Lemos et al. 2008, Wittkopp et al. 2008, Emerson et al. 2010) that might in turn be fixed by drift (Coolon et al. 2014).

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goal lines, which were extensions of the halfway line or penalty area approximately 3–30 m from each line) because multiple perpendicular views were recommended to obtain more accurate results using the MBIM technique (Krosshaug and Bahr, 2005).

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Drug specific parameters and parameter estimation
Tissue/plasma concentration ratios (Kp) were predicted for each tissue using the equations proposed by Poulin and Theil [24], Kp for the rest of body was optimised so that the predicted volume of distribution at steady state (VSS) is the same as the observed in vivo value using the following equation [25]
Kp;REST ¼ VSS;Obs VP
P Kp;T VT
70 P VT ð2Þ
The same Kp was assumed for adults and children and values for different tissues are presented in Table 1.

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Previous studies in our laboratory have established that P450 1A5 and 3A37, orthologs to human P450 1A2 and 3A4, respectively, are the most important P450 isoforms responsible for the bioactivation of AFB1 in turkey liver (Rawal et al., 2010b; Klein et al., 2000; Yip and Coulombe, 2006).

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sagittatus, was originally described from carp from the Amur River basin in Russia (Kulakovskaya and Akhmerov 1965), later on it was also found in Caspian Sea Drainage (Demshin andDvoryadkin 1981) and Japan (Scholz et al. 2001).

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Regarding the associations between the -634G[C polymorphism and hypertension, Lacchini et al. (2014) have reported that the variant genotypes of -634G[C SNP were associated with left ventricular hypertrophy in patients with systemic hypertension of Brazilian population.

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There were two measures of WMC: the reading span task
 (Daneman & Carpenter, 1980) and the spatial span task (Miyake et al., 2001, Shah & Miyake, 1996) (see Figure 1 for illustration of tasks).

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the common cascade; ligand binds to and activates the respective receptors (activin receptor-like kinase (ALK) 5 as a type I receptor and TbRII as a type II receptor for TGF-b, and ALK4 as a type I receptor and ActRIIA/IIB as a type II receptor for activin), leading to phosphorylation and activation of receptor-regulated Smad, Smad2/3 and subsequent transcriptional regulation in concert with common Smad, Smad4 [4–7].

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1), were formerly connected to the Ganges River and were progressively captured by the Indus sometime after 5 MY ago (Clift and Blusztajn 2005).

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Our results explain why soil redox status, base status, and total P content relate strongly to P mineralization (Verhoeven et al. 1996) and are consistent with observations in highly managed wetlands, where eutrophication status changed in
 response to alterations of the groundwater-regime (e.g.,‚Ä¶

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ADIPOR2 mRNA levels correlated positively and independently only with fasting triglyceride concentrations [49], whereas ADIPOR1 mRNA expression was positively correlated with serum insulin and C-peptide concentrations, first-phase insulin secretion, and elevated plasma triglyceride and cholesterol concentrations [49].

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As we have seen previously in E. coli expressed P450 3A37 (Rawal et al., 2010b), thekinetics of exo-AFBOandAFQ1 formation (1: 6) followed a sigmoidal kinetic Hill model, indicative of positive cooperativity (Fig.

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To date, 28 cases of thyroglossal duct carcinoma with clinical information for patients younger than 20 years have been reported in the English literature [4,5,7,12-15]; the histologic diagnosis was PC in 27 cases [4,5,12-15] and mixed PC and SCC in 1 case [7].

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The observations that P30 (33, 53) and vRNA (48) colocalize with the microtubule cytoskeleton and that the abilities of several P30 mutants to associate with the microtubule cytoskeleton and to support cell-to-cell movement showed a strict correlation (7, 8), indeed suggest a role for the microtubule cytoskeleton in TMV cell-to-cell transport.

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It involved a series of long, initially rather unstructured interviews [49-51].

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The medical history fields are designed to be compatible with the NCDR ICD registry elements.(15,16) In addition to these baseline variables, data specific to device

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In humans, lindane affects nervous system, liver, and kidneys, and is a potential carcinogen.(2,3,5) It has a documented neurotoxicity, i.

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As argued by Demirgüç-Kunt and Huizinga (2004), Total cost of funds is an implicit interest rate on BHC liabilities, which is inferred from its financial statements. While Total cost of funds measures the overall cost of a BHC’s debts, it can differ across banks and time due to differences in interest rates or in the maturity and structure of a BHC’s debt. We therefore construct a second funding cost measure that focuses only on deposits. Following Gilje, Loutskina, and Strahan (2016), we measure the cost of deposits as a BHC’s interest expense on domestic deposits during a quarter divided by the stock of domestic deposits at the beginning of the quarter (Cost of domestic deposits).

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Cochrane Collaboration tool for assessing risk of bias was used to assess the quality of randomized controlled trials, using the following criteria: (1) randomization sequence generation: assessment for selection bias; (2) allocation concealment: assessment of selection bias; (3) level of blinding (blinding of participants and blinding of outcome assessment): assessment for performance bias and detection bias; (4) incomplete outcome data: assessment for attrition bias; and (5) selective reporting: assessment for reporting bias.

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In many lytic phages these fitness costs result from the trade-off between lysis time and burst size [33].

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A significant amount of this money was ring-fenced for additional home-care packages (a
ª 2011 Blackwell Publishing Ltd 311
cash-for-care scheme first introduced in 2006, see Timonen et al. 2006b).

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Similar results were demonstrated for the identification of Haemophilus somnus from naturally infected bovine lungs (Tegtmeier et al., 2000), which emphasises the need of alternative detection methods to complement the culture based at establishing a definitive diagnosis.

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For example, the invasive pathogen, Listeria monocytogenes, induces the mono-ubiquitination of receptors – hepatocyte growth factor receptor (HGFR) (Veiga and Cossart, 2005) and E-cadherin and triggers the recruitment of clathrin and caveolin-1 to entry foci (Bonazzi and Cossart, 2006; Veiga et al., 2007).

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5% gelatin coated chamber slides in RPMI-B27 medium supplemented with 10% FBS, 10 uM Y-27632 (Sigma), Polybrene (Millipore) and 5000 particles per cell of a lentivirus expressing Cre under the striated muscle-specific CK7 regulatory cassette, based on the muscle creatine kinase promoter (MCK) [9–11].

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IOVS 2010;51:ARVO E-Abstract 1717).(10) In both previous studies, negative correlations between the refractive lens power and the refractive error of the eye were found, with hyperopic eyes having lower refractive lens power than emmetropic or myopic eyes.

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Based on available direct experimental measurements on several apparent two-state proteins [32, 33], here the intrinsic enthalpic folding barrier H ‡ i is taken, as a first approximation, to be a constant (independent of Gf/T ) for a given protein, but may differ for different proteins [29, 31].

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We evaluate and compare our algorithm with the SpectralUCB which is the state-of-art and outperforms its competitors such as LinUCB on graphs with large number of nodes.

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95) and using the dynamic programming method implemented by Ilie et al. (2011) on a region of 100bp, we selected the three spaced seeds with the highest ‘hit probability’ (Ma et al.

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In [3, 4, 5], the authors proposed customized two-level memory subsystems, which minimize the off-chip memory bandwidth.

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This approach is further necessitated by the complexity of the known RNA binding sites for S15 [39, 42, 43].

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Access into the portal venous system for interventional procedures has been achieved using a variety of approaches: trans-jugular (by creation of a trans-jugular intrahepatic portosystemic shunt) [4], trans-femoral (through spleno-renal or gastro-renal shunts) [5], trans-hepatic [6–9], trans-splenic [10–24], and percutaneous access through recanalized umbilical vein [25] or abdominal wall varices when available.

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Before the recommendation of American College of Chest Physicians [6], three studies reported a maximum level of PIP utilization ranging from 63€17 to 73€18 cm H2O [18, 19, 20].

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5B), but, interestingly, they shared conserved residues that are most notably found in the NQO1 family of eukaryotes (Chen et al., 2000; Faig et al, 2000).

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In [8], the authors employ a variable-length n-gram model to extract the necessary information of the sequence databases, and utilize an exploration tree to reduce the amount of added noise.

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test for BLEU is computed using the paired bootstrap resampling technique (Koehn, 2004), and for TER using the stratified approximate randomization technique (Clark et al.

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Women of reproductive age (15-49) make up close to a quarter (24%) of the total population and children under 15 years account for 47.

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Lead carbonate, an insoluble compound that is one of the major oxidation products of lead in water may be bio available to amphibians (Stansley et al. 1997).

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The results are discussed in relation to other recent work on vertebrate primary dorso-ventral patterning, including the early expression of a recently described follistatin -related chick gene (Towers et al., 1999).

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Contrary to some previous reports (3, 4, 15), in the present study junctional SCE was found to associate with erosive esophagitis, suggesting that SCE may be a result of GERD.

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Furthermore, methods to detect recently described cfr- or L4 protein-mediated resistances were applied using techniques reported earlier (Arias et al., 2008; Kehrenberg et al., 2005, 2007; Kehrenberg and Schwarz, 2006; Long et al., 2006; Mendes et al., 2008; Schwarz et al., 2000; Toh et al., 2007).

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Wilkiemeyer et al.(13) reported a correlation between resident PGY and inguinal hernia recurrence rate, which occurred after 6.

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Experiment 4: conditioned reinforcement This procedure consisted of four phases (see Morrison et al. 2011; Ranaldi et al. 2009 for details).

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MtrR also directly represses the mtrCDE efflux pump and rpoH (sigma 32) (57) (not shown in Fig.

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Skeletal muscle mass is ultimately determined by the balance between the rate of protein synthesis and protein degradation (Goodman et al., 2011c).

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applied for the evaluation of several modelling grammars, such as ER [15,16], DFD [15], ARIS [3] and others.

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Spinal cord pathway transection was performed by electrocautery as previously described
6 in detail (Chen and Wolpaw 1997, 2002; Chen et al. 2001b, 2002).

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Our definition of bipolar NOS has been validated and used in previous studies (Akiskal and Benazzi, 2005; Benazzi and Akiskal, 2006; Kim et al., 2008; Lee et al., 2009).

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SM/J and LG/J differ in their phenotypic response to a high-fat diet, with SM/J being more responsive than LG/J for many obesity, diabetes-related, and serum lipid level traits [23,24].

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A number of polymorphisms in UGT1A1 and UGT1A9 affecting expression and protein function have been identified and could potentially modulate the metabolism of SN-38 in vivo (Zheng et al., 2001; Guillemette, 2003; Villeneuve et al., 2003; Girard et al., 2004; Yamanaka et al., 2004), as well as response to irinotecan-based chemotherapy (Ando et al.

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This result is consistent with another study (deGoma et al., 2001) where an inverse relationship between HDL cholesterol and prevalence of coronary heart disease (CHD) was observed, whereas LDL cholesterol, total cholesterol and triglycerides are directly related to prevalence of CHD.

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These reference genome sequences were used: Arabidopsis thaliana (Ath) TAIR10, Arabidopsis lyrata (Aly [30]), and Arabis alpina (Aal; sequence [18] and gene annotation [18]).

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Tobacco use poses a substantial health hazard to cancer survivors [6, 7], including an increased risk of subsequent malignancies [8].

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…sperm AR stimulated by progesterone, (Luconi et al., 1995; Meizel and Turner, 1996; Kirkman-Brown et al., 2002) and LPC- and A23187-induced AR are associated with higher levels of Tyr phosphorylation of p80 and p105 (Aitken et al., 1995; de Lamirande et al., 1998; de Lamirande and Gagnon, 2002).

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Compatible with our findings, Silk et al. (2016) found that FA values that were more strongly lateralized to the left in the PUT WM were associated with greater symptom severity in patients with ADHD.

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This method is most applicable as a research standard for performance testing and algorithm comparison [3] and forces the swarm to expand its search beyond its initial limits.

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Inaccurate prediction and instability in n u me r i c a l d a t a a r e major reasons behind the shortfall of forecasters [1] [3].

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SSA responses have also been discovered in auditory thalamus (Anderson et al., 2009) and auditory cortex (Von der Behrens et al., 2009; Ulanovsky et al., 2004, 2003).

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…spectrum above-ground (i.e. trait syndromes associated with resource acquisition or conservation; see Reich 2014), the existence of a root economics spectrum is still a matter of debate, mainly because of a lack of consistency among and within studies (Mommer and Weemstra 2012; Weemstra et al.

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All rights reserved. doi:10.1016/j.expneurol.2007.06.029
interaction resulting in dedifferentiation of the Schwann cells and activation of a growth promoting phenotype (Hall, 2005).

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We have previously shown that activation of TGF- signaling is involved in the myoendothelial gap junctiondependent differentiation of PASMCs to a more contractile-like phenotype in PAEC/PASMC touch coculture (21).

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Disconnected neural network connectivity between brain regions increasingly has been proposed as a key characteristic underlying memory deficits in amnestic mild cognitive impairment (aMCI), which has a high risk of conversion to Alzheimer's disease (AD) (Bai et al., 2009a, 2009b; Sorg et al., 2007).

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reported to be 3% by another study, lymphadenopathy was not among the clinical symptoms in the south of Iran.([23]) In previous studies, the lymph node metastasis was not reported in this area.

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Because the mammalian CSC does not bind tightly to the PI3P-binding sorting nexins, it is unclear what prevents the sorting nexins from driving the formation of empty tubules devoid of cargo (Cullen and Korswagen, 2012).

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Rodent and avian NF-M subunits, while otherwise very similar to their human counterpart, contain only one or two degenerate KSPV repeats (Levy et al., 1987; Napolitano et al., 1987; Zopf et al., 1987).

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Out results also agree with that of Wang et al. (2015), who stated that serum IL-35 levels and its mRNA expression were decreased in allergic asthmatics.

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This experiment may be difficult as two different studies observed that severe bottlenecks are present in the colonization process of the chick gastrointestinal tract when an inoculum is used that contains more than one strain of C. jejuni (Hendrixson and DiRita, 2004; Grant et al., 2005).

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(2010) demonstrated that the development of external sexual change of krill is accelerated by photoperiod, although others have shown that the cyclic maturation process is maintained independent of direct control by environmental factors such as food or light (Thomas and Ikeda 1987; Kawaguchi et al. 2007).

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