This could be explained by the requirement for specific spacers that match the invader DNA (Barrangou et al., 2007; Brouns et al., 2008; Marraffini & Sontheimer, 2008), and also by the existence in E.

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Interestingly, despite the possible impact of training programmes, Stanton et al. (2005) maintain that improvement in these areas also brings a greater likelihood of writing down one’s password, or even sharing passwords, which indicates a lack of InfoSec awareness (Dinev and Hu 2007).

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(Meis-Kindblom et al. 1995; Antonescu et al., 2001), whereas LGFMS has been characterized as having a “low-grade” protracted clinical course with local recurrences and late metastasis (Evans, 1987, 1993).

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…the lesions with pure SEF morphology (90% of patients), feature that has not been documented previously in the largest SEF series published to date (Meis-Kindblom et al., 1995; Doyle et al., 2012; Wang et al., 2012), except for a slight female tendency in Antonescu et al. (2001) SEF cohort, in…

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We used the same setup that was used by McIntosh & Lashley [11] and Borchers et al.

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This method, which we used previously (22, 24), maintained a constant temperature, pH, PCO2, and PO2 of the suffusate during infusion of drugs.

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…were: (1) Enlarged ventricles out of proportion to sulcal atrophy on computed tomography or magnetic resonance imaging (Evan’s index of at least 0.3; Shprecher et al., 2008), (2) Gait disturbance with either urinary incontinence and/or cognitive impairment, (3) No evidence of a known cause for…

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In line with past studies (e.g., Anderson et al., 1998; Craik et al., 1996) results of the current study showed that secondary task performance i.e., the RT task, was disrupted to a greater extent when attention is divided during retrieval than when attention is divided during encoding.

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For example, although some research indicates that forests can sustain increased productivity under elevated CO2 by enhancing N uptake (Finzi and others 2007), few studies have followed forests through important stand development phases (for example, establishment, canopy closure, age-related declines in stand productivity) to examine whether the early stimulation of plant productivity by elevated CO2 persists as stands mature after reaching maximum productivity (Körner 2006).

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As a result, MEK protein, like the MAPK family of proteins, may comprise a family of enzymes regulated by a variety of stimuli and in different cell types (5, 10); (/>) disorders of phosphatase(s) that negatively regulate MAPK activity may exist.

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During the early stages of autophagic induction, LC3-I is conjugated with phophatidylethanolamine, to produce LC3-II (Mizushima and Yoshimori 2007).

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Intestinal permeability was determined using the Smurf assay, as described by Rera et al. (2011), (2012).

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…experiments and numerical analyses of stratified flow provide more tangible evidence that buoy-
ant gravity currents, characterized by a convergent front, can lead to accumulation and transport of buoyant particles in the direction of the propagating front (Franks 1997, Helfrich & Pineda 2003).

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F proteins are acid pH dependent and contain a predicted signal peptide at the amino terminus, a transmembrane domain near the carboxyl terminus, up to 11 conserved cysteines, and a furin cleavage site (40, 51, 56).

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In agreement with findings showing that PLCb1 is mostly located at presynaptic sites (Fukaya et al., 2008) and with its apparent absence from the PSD-95 complex (Dosemeci et al., 2007), the intensity levels of PLCb1 and PSD-95 signals were not correlated each to other, as expected for two proteins…

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It had 2565 (2805) states optimized with the variational Bayesian estimation and clustering (VBEC) technique (Watanabe et al., 2006) and each state had 32 (32) -mixture Gaussian pdfs.

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Preterminal and terminal Schwann cells serve as a growth substrate that guides the nodal sprouts to the original endplates of denervated muscle fibers (Son and Thompson, 1995b; Koirala et al., 2000).

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in the brain of ALS and FTLD patients are highly prone to aggregation.(17,22,31,32) Furthermore, it was reported that wild-

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Mutation sites in the receptor-binding domain of the spike protein The spike protein of CoVs is responsible for cell receptor attachment and membrane fusion to mediate virus entry (Li, 2015).

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However, several studies [3,4,5] of bipolar patients with and without lithium treatment have found similar results in personality.

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Using the final XML description that contains the intended architecture, we are able to perform a final architecture analysis to measure the violations in the code of the intended architecture (and thereby to measure the architectural decay [11] of the code).

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Moreover, although we lacked specific phylogenetic information for our species, the general patterns we observed were robust to topological uncertainty, and equal branch lengths are associated with fewer errors than other topological approaches (Ackerly 2000).

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by the ICMJE [16], and none limited inclusion to trials completed after the 2007 U.

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The presence of the SWI/SNF and RSC chromatin remodeling complexes at the HIR-dependent histone genes has been previously reported to be dependent on the Hir proteins [22,23].

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There are now several papers (for instance [12, 3, 4, 5, 6]) with bounds polynomial in the number of variables concerning the quadratic case.

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Here, we rely on the freely available implementation of the Haar face detector that ships with the OpenCV library [3].

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aureus according to conventional methods, including Gram staining, colony morphology, hemolysis, catalase and tube coagulase test, as well as 16S rRNA, coa and nuc gene sequence analysis, as described [6, 10].

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We adopted the Th.o.m.a.s., an interview aimed at an articulated exploration of ToM (Bosco et al., 2009a; Castellino et al., 2011) and an advanced ToM test, namely the Strange Stories test (Happé et al., 1999), aiming to provide a complete assessment of such complex cognitive ability.

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We used lipid/biomass ratios and tissue thickness as measures of coral health at the time of collection [25,44].

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Furthermore, curcumin has been shown to be a potent immunomodulatory agent that can modulate the activation of T cells, B cells, macrophages, neutrophils, natural killer cells, and dendritic cells (Allam 2009).

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The manifold assumption states that input samples with equal class labels are located on manifolds or subspaces, respectively, of the input space (Belkin et al. (2006), Bilenko et al. (2004)).

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An example of the OR request model is a read request for a replicated data object, where reading any copy of the data satisfies the request [16].

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The NE turnover rate is calculated as the product of k times the endogenous concentration of NE at time 0 (1).

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9 for a normalized kinetic energy of = 12 ( p= Y)v 2 0 = 0:2, corresponding to the Berkeley experiments wherein a steel ball impacts Ti–6Al–4V at v0 = 300 m=s (Peters et al., 2000, 2002; Boyce et al., 2001b).

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1b), such as triglycerides, sphingomyelins and phosphatidylcholines, encompassing many lipids associated with risk for developing type II diabetes (Floegel et al. 2012; Rhee et al. 2011).

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fast growing and nutrient sensitive) bacteria in seawater recruiting to the mucus matrix and increasing rapidly in abundance (Allers et al. 2008).

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The median operative time in our study was 82 minutes for LA, which is relatively longer than that reported by other studies.[20-22] This

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The importance of reliable M-shell Fe DR data has also been shown by the analyses of recent Chandra and XMM AGN spectra.

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Minimizing the first two terms of equation 6.7, which are
7 This mechanism was proposed in Amari (1977) and Pouget and Zhang (1997).
of order 1, determines that the stable state is on the line attractor.

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(1986) using 5S rDNA probes obtained by PCR from Prochilodus genomic DNA using the primers A (5_-TACGCCCGATCTCG TCCGATC-3_) and B (5_-CAGGCTGGTATGGCCGTAAGC-3_) (Pendás et al., 1994).

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Online retrieval for SNP genotype information from NCBI using SNP ID and gene input is similar to the function described in the SNP-Flankplus [17] and SNP ID-info [18].

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The factors associated with the increased rate of anastomotic dehiscence are: atherosclerosis, anemia, low anastomosis site, diabetes, advanced age, bowel perforation or obstruction, and total mesorectal excision (TME) [6, 9].

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A modified version of the ‚ÄùMaze Game‚Äù, devised by Garrod and Anderson (1987) was developed. This task creates a recurrent need for pairs of participants to produce location descriptions. These descriptions can be reliably classified into four broad categories (see below). Alignment of the category of description used by participants can then be used as an index of semantic coordination (Garrod and Anderson, 1987; Garrod and Doherty, 1994). To support turn-level experimental manipulations of the dialogues the chat-tool technique described by Healey, Purver, King, Ginzburg, and Mills (2003) was used.

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RAG-mediated cleavage of oligonucleotide substrates, PCR-generated long DNA fragments, or plasmid DNA was analyzed using an in vitro cleavage assay described previously [24].

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Given the statistical advantages to using age- and sex-specific BMI Z-scores (Must & Anderson, 2006), we chose to test hypotheses using BMI Z-scores as the dependent variable.

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00D between the right and left eyes.[8,14,18] Although photorefraction is not able to accurately determine refractive measurements in eyes with myopia>7.

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The high-resolution crystal structures of AChBP‚Äìneonicotinoid complexes with IMI and THIA reported here, and in earlier findings for an EPIoccupied AChBP crystal structure (4) and its nicotinic agonist relatives (11), are generally consistent with the results of photoaffinity labeling in a physiological condition with 5-azido-6chloropyridin-3-yl IMI, THIA, and EPI probes (12‚Äì14).

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Little is known about the ranges at which toothed whales detect prey in the wild (Au et al. 2004, Madsen et al. 2004), but the extensive studies on trained delphinids in target detection experiments may offer a useful framework to estimate the range at which a squid of known TS can be detected.

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Other sources of MF and SB input to the GCD are the lateral reticular nucleus, the pontine nuclei and inferior olive (Weinberg and Rustioni, 1987; Zhou and Shore, 2004; Ryugo et al., 2003), as well as the contralateral CN (Zhou et al., 2010).

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[17] described that lower gestational age had more chance of colonization, but in contrast to their findings, we found that gestational age was not significant for colonization.

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Expression values for PIF3 were calculated using the equation 2-ΔΔCt, and 18S rRNA served as the control (Livak and Schmittgen, 2001; Pfaffl, 2001).

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Parameters are chosen as in Abeler et al. (2010) such that higher effort by agents is always socially efficient, but principals and agents have immediate material incentives to free-ride and avoid the cost of paying high wages or effort costs, respectively.

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Although standard economic models based on the idea of utility maximization take more choice to be unambiguously welfare-enhancing, scholars have argued that availability and use of certain products can in reality be detrimental to the society (Crane et al., 2014; Karnani, 2007).

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These results seem to contradict previous findings indicating that alcohol-related harm is closely related to prices on distilled spirits [7-12].

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…and Sieving 1995; Frishman et al. 1996), but during rod vision, neural adaptation is apparent at light intensities too low to cause adaptation of rod phototransduction (Barlow and Levick 1969; Enroth-Cugell and Shapley 1973; Frishman and Sieving 1995; Naarendorp et al. 2001; Saszik et al. 2002).

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In studies examining dose–response relationships between knee-straining work activities and degenerative knee disorders, retrospective exposure assessment has usually been based on self-reports (Felson et al. 1991; Vingard et al. 1991; Coggon et al. 2000; Sandmark et al. 2000; Seidler et al. 2008; Muraki et al. 2009; Klussmann et al. 2010).

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In
addition, there are continued new developments in lowcost, light-weight, and long-duration UAVs (Lucieer et al. 2014).

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In this experiment, we also use the 10-fold cross validation, and we also use the F-score, AUROC, and RPBEP performance measures.

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Longini et al. (2004) used values that were similar to these estimates in a stochastic simulation model of pandemic influenza to show that the targeted use of oseltamivir in close contact groups could slow the transmission of influenza on the community level.

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The values of the free parameters mij ∈ [0, 2], bij ∈ [0, 1], and aij ∈ [−2, 2] are searched to find a betterperformed fuzzy predictor.

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These results support those of Good et al. (2001) who also found that, compared with men, adult women had higher WM density bilaterally within the internal capsule.

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The Newman index of degree assortativity (Newman 2002) is equal to 0.24 implying that highly intra-collaborative researchers moderately tend to be directly connected among themselves.

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The process capture was facilitated by considering a modelling case study based on the development of a model for a field campaign that took place in Tasmania, SOAPEX [4].

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To control for access to other home- and community-based services (HCBS), at the market level, defined by county boundaries, I controlled for home care capacity using the number of home health agencies per 1,000 people aged 65+ in the county (Hahn et al., 2011).

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…multiple genes interact with psycho-socio-cultural factors in determining an individual’s overall liability to develop these disorders [Dick and Foroud, 2003; Higuchi et al., 2006], genetic factors alone may account for up to 50–60% of the variance in the population [Tyndale, 2003; McGue, 1999].

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But concurrently, Amazon competes with Apple on the device layer with its own Kindle eBook readers and tablets [57].

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Elsewhere, I demonstrate that non-breeders avoid becoming actual
competitors for reproduction, and thereby avoid eviction, by modifying their growth and remaining small (Buston 2003b).

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These values are consistent with previous studies (Akiyama et al. 2010; Liu et al. 2009; Wilson et al. 2011).

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Finally, our results indicate that sustainability planning focused on securing additional funds and aligning the program with the implementing organization is a key predictor of sustainability across program types, thus supporting sustainability theory (Johnson et al. 2004) and previous empirical work with this sample (Tibbits et al.

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…813 ± 82 831 ± 55
a aa, amino acids. b Based on within-vertebrate divergence times. c Based on animal–fungus divergence times.
invertebrate divergence time is more reliable than theirs, because mitochondrial genes they used are not evolving in a clocklike fashion in vertebrates (Nikoh et al. 1997).

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Also in data centric storage (DCS) [24, 27, 42, 56], the election of storage nodes may not be possible if the hashed location for a certain event is within certain holes.

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…a 15-mm sphere functional ROI for dorsal pons [2 30 32] was derived from previous work demonstrating its sensitivity to first order representations of bodily state (Critchley et al., 2001), implicating it in anger processing (Damasio et al., 2000) and core aspects of emotion (Damasio, 2010).

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In barley roots, using GGT inhibitors in association with the thiol oxidizing molecule diamide resulted in a net glutathione extrusion and accumulation in the extracellularmedium (Ferretti et al., 2009).

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A number of studies have delineated in DAFC-66D the 320bp Amplification Control Element on the third chromosome, ACE3, required for high levels of amplification (Figure 3C) (de Cicco and Spradling, 1984; Delidakis and Kafatos, 1989; Orr-Weaver et al., 1989; Orr-Weaver and Spradling, 1986).

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To fulfill these functions, Hsp90 interacts with its cofactors and cochaperones including Hsp70, immunophilins, and p23, to form the Hsp90based chaperone complex.(1,2) Natural compounds such as geldanamycin and radicicol bind the ATP-binding pocket of Hsp90, and disrupt its chaperone function.

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Our extensive sampling of the first exon of bindin over the entire species range has confirmed the finding of McCartney and Lessios (2004) from Panamanian populations that selection is acting on this molecule in E. lucunter.

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In Igf2mutantmice, nutrient transporters are initially upregulated when there is first evidence of maldevelopment of the interhaemal compartment in the placental labyrinth layer (Constância et al. 2002; Sibley et al. 2004).

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an XX/XY or ZZ/ZW system, respectively), individuals of the heterogametic sex possess sexspecific genomic regions for which sex-specific molecular genetic markers can be developed (Gamble 2016; Griffiths and Tiwari 1993).

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Antibiotic production is perceived to provide a fitness benefit to the producer by inhibiting the growth of competing microbes (Williams and Vickers, 1986; Firn and Jones, 2000; Davelos et al., 2004a).

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previously hypothesized that disturbance in the pseudoautosomal regions may disrupt pairing of the sex chromosomes during meiosis [13].

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In the Pascal VOC Part dataset [3], we used four parts for the bird category.

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The other potential source of discrepancy in the results between the two studies is the experimental task – in the study of
Todd et al. (2004) the subjects had to specify the position of the local extrema of the depth function on a single scan line while in the present experiment the subjects had…

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We consider as unknown true system the half-load model of the flexible transmission system used as a benchmark in a special issue of the European Journal of Control (Landau et al., 1995b).

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Exercise has been recommended for the prescription but the exact intensity of physical activity is still unclear (Duschek and Schandry, 2007).

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Our results agree with previous
19
reports showing that a single exposure to dexamethasone rapidly stimulated Sgk1 mRNA in cell cultures (Wang et al., 2007) and that a single injection of DEX in vivo resulted in increased Fkbp5 mRNA in mice (Scharf et al., 2011).

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…of the most abundant synaptic proteins, Ca2+/calmodulindependent protein kinase II (CaMKII), is concentrated at postsynaptic densities (PSDs) in spines (Kennedy et al., 1983), along with downstream substrates, including NMDA receptors (NMDA-Rs) and AMPA-receptors (AMPA-Rs) (Yoshimura et al., 2000).

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We use Minimum Error Rate Training (MERT) [17] for tuning the lambda values for all systems, and we report results in terms of BLEU score [18] on lowercased output with tokenized punctuation.

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Concerning age, other studies that included dogs treated with trilostane or mitotane have reported similar results.(33,35) In contrast, age was not reported to be associated with survival in another study that included dogs treated with trilostane, and our results are consistent with theirs.

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…or slightly improved discrimination even when comparing our results to the subset of studies that used a GRS constructed with a similar set of SNPs (Brautbar et al., 2012; Hughes et al., 2012; Thanassoulis et al., 2012; Ganna et al., 2013; Thanassoulis et al., 2013; Tikkanen et al., 2013).

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While our objective, the symmetric difference, is similar to the one used in k-effector [21], our novel formulation does not require the knowledge of the number of infection sources k.

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It is to be noted that the theories for SNRe and CNRe (Varghese and Ophir 1997R, 1998) provide upper bounds on the corresponding values and, therefore, the simulation and experimental results are expected to be lower than the theoretical values.

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Metaanalysis was undertaken using the meta command in PLINK [19] in the entire samples and in a sample limited to individuals treated with a serotonergic antidepressant.

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The techniques used in this field [3], [4], [5] have to do with agent-based models and simulations.

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The polydispersity value of 3.9 observed for the two-stage, OS7 derived lignin (Table 5) was relatively high when compared to previously reported values (Pan et al., 2006b).

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Previously, we reported that HMGA1 is a novel target of ATM following DNA damage (Pentimalli et al., 2008).

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1986) and used to determine ptDNA copy number (Oldenburg and Bendich 2004; Zheng et al. 2011).

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17Recently, Davidsson & Sibbertsen (2002) introduced a model which nests the Error Duration model of Parke (1999).

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Consistent with previous reports that acute in vitro exposure of brain slices to kynurenine enhances KYNA synthesis (Turski et al., 1989; Gramsbergen et al., 1997; Scharfman et al., 1999), incubation of rat hippocampal slices with 200 M kynurenine led to a continuous de novo synthesis of endogenous‚Äö√Ñ¬∂

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Moreover, canids are the only known eutherian mammals to carry a Prdm9 which has acquired disruptive mutations (Mu~ noz-Fuentes et al. 2011; Ponting 2011; Axelsson et al. 2012) (a marsupial, the opossum Monodelphis domestica, has a Prdm9 which lacks zinc fingers; Ponting 2011).

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The low level of Cd can be attributed to its continuous removal by leafy green plants grown in the designated areas (Yadav et al. 2013).

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…but moderately correlated with reaction time interpretation bias, suggesting that the two measures assess separate but related processes (Amir et al. 2012; Beard and Amir 2009).1 Given the intriguing but somewhat contradictory findings of these preliminary WSAP studies, we sought to…

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In a third cross-sectional study of 680 elderly men in the US, long-term exposure to traffic-related air pollution was associated with lower Mini Mental State Examination (MMSE) scores as well as with lower global cognitive function (Power et al. 2011).

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Such results may point out that ROS might be the major mechanism of the nanoHA‚Äì ZnO granules‚Äô antibacterial effect, which is in good agreement with other reports [10, 28].

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Other clinical scales used were the Hamilton Depression Rating Scale (HDRS) [34], the Young Mania Rating Scale (YMRS) [72], the severity subscale of the Clinical Global Impression Scale (CGI) [25], the Global Assessment of Functioning Scale (GAF) [19], and the Premorbid Adjustment Scale (PAS) [10].

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Several practical, environmental, and biochemical characteristics of EOs make them a potential alternative for insect pest management [3,4].

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This is important because organisms seldom follow a single optimal path [43], and because redundant connections help to ensure continued connectivity in the face of unpredictable environmental changes [15].

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Cells were analysed on a FACScan device (Becton Dickinson) as described previously (Hu et al., 2004).

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Executive functioning or meta-cognition was examined using either the Behavior Rating Inventory of Executive FunctionParent (BRIEF) [Gioia et al., 2000] or the Behavior Rating Inventory of Executive Function Adult Version (BRIEF-A) [Roth et al., 2005].

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For the formal definition of safety an areaS was introduced in (Rüdiger et al., 2007a) and further discussed in (Rüdiger et al., 2007b), which leads to catastrophic consequences when left.

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The conditions of the incubation reactions as well as the concentration of the substrate reaction probes utilized were established based on previous CYP450 inhibition studies by our group in human liver microsomes [20‚Äì24].

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[8,18] These signs as well as others could be used to help develop a diagnostic algorithm, as proposed by Nguena et al, to help clinicians identify OSSN and know when to appropriately refer for more specialized care.[8] Tumor depth could also provide a simple clinical measure to use in order to differentiate between high risk OSSN and benign lesions.

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The first experimental contribution to unravelling the molecular mechanism of CRISPR processing came from Escherichia coli studies (Brouns et al., 2008).

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Generation of overlays to compare molecular shape and charge distribution with a known ligand
In addition to property and pharmacophore-based filtering, Screenlamp invokes the ROCS [10] software to generate 3D molecular overlays to evaluate similarity in volumetric and chemistry (or “color” [69]).

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This fact agrees with our previous data, which showed that ATP production after UV treatment is attributable to the metabolism of the DNA degradation products [2].

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This suggests a generalized reinforcement rule that is still in the class of EWA [12, 18] approaches:

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In addition, I followed the approach pioneered by Brownlee et al. (1969) and Novotny et al. (1986, 1990b) and compiled examples of differences in composition between secretions (in the broadest sense, i.e. including urine, faeces, breath etc.) from different categories of mammal, (for example,…

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A number of studies have been published recently, which analyze the location, orientation, and identity ofmacromolecular complexes, based on the outcome of template-matching (Brandt et al., 2009; Ortiz et al., 2010).

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…it has been recognized that Tertiary Neogene tectonic and palaeogeographical reorganization have also been important drivers of the origin of Neotropical (Pennington et al. 2004; Hoorn et al. 2010; Rull 2011) and temperate biodiversity (Quiroga & Premoli 2010; S ersic et al. 2011) in South America.

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1998), to provide great £exibility in testing evolutionary hypotheses (Huelsenbeck & Rannala 1997), and simply to give excellent results in the inference of evolutionary relationships (Kuhner & Felsenstein 1994; Huelsenbeck 1995). Constraints imposed by computational complexity are becoming less restrictive as computers improve. Given the recognition of phylogenetic inference as being inherently statistical in nature, it is surprising that so little attention has been paid to experimental design. A number of topics of relevance to experimental design in phylogenetics have been discussed previously. There is something of a folklore surrounding the choice of genes or other genomic regions for investigating particular evolutionary questions, but almost no published quantitative results. It is widely accepted that sequences that have undergone very little evolutionary change since their divergence from a common ancestor, through low substitution rates or short evolutionary times, will exhibit too few di¡erences to contain useful evolutionary information. Equally, sequences that have undergone very large amounts of change (high rates or long times) become `saturated' with changes and no evolutionary signal is detectable amid the noise. Consequently, a happy medium is expected at some intermediate level of sequence divergence, but the àsymptotic' results (for extreme high and low levels of divergence) give no clue as to where this lies. Although there is considerable experience with particular genes and organisms (see Hillis et al. (1996, pp. 336^339) for an extensive list of studies), where comparisons among genes have been made they tend to be evaluated empirically by the congruence of the results obtained among themselves and with researchers'a priori expectations. In addition, a large laboratory e¡ort is needed before even these qualitative conclusions can be reached. The methods introduced in this paper can quantify the e¡ects of varying levels of divergence. They con¢rm the belief that intermediate levels of...

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Measurements of pH and pepsin in the refluxate thus provide information helpful to an understanding of the pathophysiology in these patients (17, 23, 39).

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In addition to expression in the fetus, Igf2 is expressed by the placenta (Constância et al. 2002) and mice lacking the placenta-specific Igf2 transcript show IUGRaswell as placentas that are small and have altered nutrient transport (Constância et al.

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CDDO-Me is a synthetic triterpenoid that was under phase III clinical development for the treatment of advanced chronic kidney disease (37, 38) However, due to adverse events in the phase III clinical trial, further development of CDDO-Me was terminated (39).

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Nevertheless, previous studies from the same setting in 2011 [23], and subsequently in 2012–2014 [38], persistently identified a role of B.

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Efficient phytoextraction species should translocate high quantities of heavy metals (HMs) into their aboveground biomass without toxicity symptoms, and at the same time produce large amounts of biomass (Vangronsveld et al., 2009; Luo et al., 2016).

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…from the word meaning in a color–word Stroop task (Fan et al., 2003; MacDonald et al., 2000; MacLeod, 1991) or from flankers in a flanker task (Fan et al., 2003; Casey et al., 2000; Botvinick et al., 1999; Cohen & Shoup, 1997; Eriksen & Eriksen, 1974)] can be estimated as less than or equal…

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A region with considerable high lead occurrence is the Beaufort Sea which is in accordance with the results ofMiles and Barry(1998). Rigor et al.(2002) described the ice drift in the Beaufort Sea, which follows the rotational movement of the Beaufort Gyre.

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This hypothesis is supported by the previous studies indicating that RAN was targeted by vesicular stomatitis virus to block transport of RNAs and proteins between the nucleus and cytoplasm of Xenopus laevis oocytes [50].

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Oral disposition index (DI), a measure of pancreatic b-cell function in response to ambient insulin sensitivity, was calculated as: INS0‚Äì60/GLC0‚Äì60 9 Matsuda index (Abdul-Ghani et al. 2006; Miyazaki et al. 2008).

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Most of these atlases are based on a single animal (Cannestra et al., 1997; Saleem and Logothetis, 2006; Van Essen, 2002, 2004); while others are based on small samples of 6–12 animals (Black et al., 2001a; Black et al., 2001b; Greer et al., 2002; Vincent et al., 2007).

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Approximately 1/3 of the glucan in DGS is starch, indicating the need for amylase as well as cellulase (Kim et al., 2008a).

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Using this strategy, we generated HA-tagged chimeras encoding the N-terminal domain of PR NS1 fused to the C terminus of Tx NS1 [PR(1-80)Tx(81-230)] and vice versa [Tx(180)PR(81-230)].

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A growing number of animal studies showed that imaging or therapeutic agents larger than the BBB’s exclusion threshold of 400 Da could be successfully delivered by FUS with microbubbles (Alonso et al. 2013; Choi et al. 2007; Choi et al. 2010a; Hynynen et al. 2001; Kinoshita et al. 2006; Marquet et al. 2014; Shen et al. 2014).

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This supports and complements the recent results of Baik, Deift, and Johansson (1999), who apparently knew of the monte-carlo results of Odlyzko and Rains (2000).

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While previous pharmacological studies of AVP have often yielded ambiguous anxiety results, the most consistent data on the effects of AVP is the stimulation of a stereotypy of scratching and autogrooming (Meisenberg, 1988; Moody et al, 1988).

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, 2010) and Zn (Religa et al., 2006) have been observed in the cortex of human AD patients.

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oped a new scoring system based on consensus between clinicians that allows better correspondence between the vastly adopted CBCL scale and the currently employed DSM-IV diagnostic criteria [3, 4].

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The commercial vaccines, Gavac and TickGARD, contained the recombinant R. microplus Bm86 gut antigen (Willadsen et al. 1989; Rand et al. 1989; Rodríguez et al. 1994; de la Fuente and Kocan 2003; de la Fuente et al. 2007a).

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Neuropsychological testing
Participants completed the World Health Organization (WHO)/NIMH/UCLA international battery (Maj et al. 1993, 1994) consisting of measures designed to assess the following skills: motor speed and fine motor control, verbal and visual memory, attention, and cognitive…

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These morphologic findings in nonhuman primate fetuses are comparable with early anatomic descriptions of the DV morphology in human fetuses.(9,11,14,15) The intrahepatic BPV in nonhuman primate fetuses possess a well-organized media with a higher density of smooth muscle cells than the isthmic portion of the DV.

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We can then use Uppaal [12] to check the satisfiability of φ over finite timed words, or LTSmin [10] with opaal front-end to check satisfiability over infinite timed words.

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The fiber length distribution and coarseness were measured using a fiber quality analyzer (FQA, OpTest Equipment Inc., Hawkesbury, Canada) with an average of 5,000 fibers analyzed as previously described (Ju et al. 2013b).

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We will therefore continue to use the previously suggested nomenclature of hKL (Dioumaev and Braiman, 1997a) to indicate the “late” or “last” hK intermediate, which relaxes directly to hL in the room-temperature photocycle and which is the structural analog of KL (or KL) in the bR photocycle.

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The single study we examined that was limited to trials initiated after the ICMJE statement still found primary outcome inconsistencies in 15 of 55 (27 %) included trials [16].

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[11] take the simplest possible approach to constructing a subspace which captures the variation in illumination.

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The defects of yeast ubc9-1
mutants in the degradation of B-type cyclins may also indicate a link between SUMOylation and ubiquitin-mediated proteolysis (Seufert et al
., 1995).

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recent studies have shown that lifetime incidence could be as high as 25 % [1, 5].

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MacLeod, personal communication) in a small, isolated mountain range (Cerros del Sira) in Huánuco department (Herzog and Kessler 1998; MacLeod et al. 2006; BirdLife International 2011d; Gastañaga Corvacho et al. 2011). Gastañaga Corvacho et al. (2011) presented evidence for elevating both subspecies to species rank, which is followed here.

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A recent qualitative study explored the views of individuals living with SCI towards the descriptive systems of six established instruments (15D, AQoL 8-dimension questionnaire (AQoL-8D) [28], EQ5D-5L [29], HUI, QWB-SA [30] and the SF-36v2 [31]) [32].

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By modulating the membrane conductance of the postsynaptic neurons, tonic inhibition greatly influences the excitability of single neurons as well as networks [14].

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At the same time, Snail also regulates the transcription of Ncadherin [21, 22].

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An extensive survey of features for quality flaw recognition has been provided by Anderka et al. (2012). We selected a subset of these features for our experiments and grouped them into four feature sets in order to determine how well different combinations of features perform in the task.

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Andean uplift was one of the major drivers of biodiversity organization in South America (Gentry 1982; Jørgensen & Le on-Y anez 1999; Antonelli et al. 2010; Hoorn et al. 2010).

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Since the elements of the p √ó p coefficient matrix in VAR model should be estimated and determined whether they are zero or not, we use Lasso for sparse learning like BSSMVAR.

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This issue has very little been studied in the context of reproductive outcomes (Brauer et al. 2008).

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However, evidences of CPGs structures have been proposed for human (Duysens and Van de Crommert, 1998; Marder, 2000), initially for locomotion while recent insights suggest that the concept of CPG applies to the upper limb as well (see e.g. Dietz, 2002; Zehr et al., 2004; White et al., 2007).

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A MANET [14] consists of a set of mobile wireless terminals forming impromptu networks on the basis of nodes’ encounters while they move in a shared ph ysical environment.

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The regularization method introduced in [16] and our present regularized method were conceived with quite different purposes.

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Antibody-specific escape mutations in HIV-1 typically occur within the epitope targeted by the antibody (Andrus et al., 1998; Diskin et al., 2011; Horwitz et al., 2013; Klein et al., 2012; West et al., 2013), although allosteric mutations may also alter antibody binding in some cases (Bradley et…

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Patients with hyperuricemia often have glomerular hypertrophy and tubule interstitial injury independent of intrarenal crystal formation [6, 7].

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However, these results are in contrast to those studies that suggest that only osteocytes are capable of stimulating osteogenesis (Heino et al., 2004; Hoey et al., 2011).

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mine (DA), norepinephrine (NE), and serotonin (5-HT) reuptake, and the enhanced monoaminergic signals lead to addictive behaviors (Ritz et al. 1990; Ritz et al. 1987).

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However, this was inconsistent with the investigations that showed a generally higher abundance of the tryptophan-like components in Lake Taihu than in its tributary samples (Yao et al. 2011; Zhou et al. 2015).

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SphK1 was found over-expressed in ovarian cancer [30, 31], participating tumorigenesis and tumor cell resistance [30–32].

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The most common carboxylates in root exudates (citrate, malate, malonate, acetate, fumarate, succinate, lactate and oxalate) are primarily involved in respiration, stomatal regulation and other metabolic pathways (Rengel and Marschner 2005).

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Typically however, when a fungus was isolated from a seed, it was the only isolate, and roughly 74% seeds were free of all culturable fungi (Shipunov et al., 2008).

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Anderson and von Meyenburg (1) likewise observed that the specific rate of respiration by E.

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1 The stratified bisimulation relations (Milner, 1980; Hennessy and Milner, 1985) ∼k⊆ Pr× Pr for k ∈ N are defined as follows:

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In an attempt to overcome this limitation, Achenbach, Dumenici, and Rescorla [4] developed a new scoring system based on consensus between clinicians that allows better correspondence between the vastly adopted CBCL scales and the currently employed DSM-IV diagnostic criteria.

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CGRP increases the proliferation of osteoblasts (9,17), prevents bone loss when delivered systemically to ovariectomized (OVX) rats (18).

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GSH/GSSG, reduced PC/oxidised PC, and reduced Protein/oxidised Protein) can protect cells from oxidative damage (Tsuji et al., 2002), this produces an imbalance in the redox status that may lead to other unwanted effects such as changes in intracellular pH, which is, to our knowledge, an effect that has not been explored to date.

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The persistence of arctic ground squirrels in the low elevation-meadow and alpinemeadow habitats in 2008–10, and the simultaneous extirpation of ground squirrels from the boreal forest since 1998 (Donker and Krebs 2011), provides supportive evidence that the boreal forest is functioning as sink habitat for arctic ground squirrels.

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As previously demonstrated by our group (20), the BHT model resembles human UIP because of clear evidence of alveolar collapse and chronic scarring, typically patchy subpleural or paraseptal distribution, evidence of active fibrosis as fibroblastic foci, and intervening normal areas.

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In agreement, repression of Fgf signalling results in a similar but much stronger phenotype compared to down-regulation of Satb1, with all ICM cells expressing EPI lineage markers (Frankenberg et al., 2011; Yamanaka et al., 2010).

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Our results are in agreement with previous ones (Gabrielson et al., 2002; Al-Bakri and Afifi, 2007), so that such assays seem to be not particularly useful for enterococci.

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’s [14] study had an exercise regimen consisting of a variety of endurance activities which included a cross-training mix of treadmill walking/jogging, stationary cycling, seated rowing, stationary stair climbing and weight training.

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movements that are relevant to late stages of folding, as described elsewhere (60,78).

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This is regarded as the onset of the average Si-O coordination number increasing from 6 to 6+ (“6+-fold (Si)” in this figure) in each glass (see Murakami and Bass 2010, 2011).

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Demonstration of intrathecal immunoglobulin and antibody synthesis are powerful tools for diagnosis of neurological disorders, as has been shown for multiple sclerosis and several infectious diseases of the CNS (Reiber and Lange, 1991; Felgenhauer and Reiber, 1992; Andersson et al., 1994; Tumani et al., 1995; Reiber and Peter, 2001).

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‚Äö√Ñ¬∂in cuticle thickness reported
 here is in agreement with other studies which show that cuticle thickness increases (e.g. Gratani and Bonito 2009; Varone and Gratani 2009) and wax formation continues (e.g. Bukovac et al. 1979; Gu√É√†lz et al. 1991; McWhorter et al. 1990) throughout leaf expansion.

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LASTZ represents a new implementation of the previous BLASTZ (30) algorithm and includes several improvements (29).

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each capture the contributions of classes of radiation effects: hard, collinear and wide-angle soft radiation [34–39].

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We compare SISI with the dynamic programming algorithm, temporarily called k-effector, in [21] when the infection process follows the IC model.

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Figure 6 shows the segmentation of the AVG page with the implementation of the BOM approach.

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The membrane fluorescence and lipid fluidity of cells were measured in accordance with the method described by Shinitzky and Inbar [30, 31].

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On the other hand, transgenes were expressed in the central nervous system and in the retina, tissues where collagen VI was not detected (Marvulli et al., 1996).

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, 2003), none identify specific mechanisms by which successful invaders establish and expand their new ranges (Ehrlich, 1989; Mack et al., 2000; Viet and Lewis, 1996).

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The update rule above is a special instance of a more general experience-weighted attraction rule [12, 18], which has been shown to be in reasonable agreement with experimental data on human learning in repeated games.

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RNA molecules are extremely sensitive and easily degraded by ribonucleases (RNases) or contaminated by genomic DNA during the isolation process (Schroeder et al. 2006).

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The third model, which assumes unrelatedness, accounts for the possibility “that the blunted VS response as observed in individuals with ADHD is related to additional disease-related factors and not trait impulsivity per se” (20).

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For the linguistic feature extraction phase we wrapped several state-of-the-art NLP tools: Stanford CoreNLP12 for POS, NERC, TERN, and coreference resolution; mate-tools13 for DP and SRL, with mappings between frame resources from the Predicate Matrix [10]; DBpedia Spotlight14 for EL; and, UKB15 for WSD.

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Firstly, the intracellular phosphoprotein networks investigated (pathways or single mediators integrating signaling through several pathways) are important for downstream signaling from growth factor receptors commonly expressed by primary human AML cells [12, 13].

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For cartilage staining, embryos were fixed for 2 hours to overnight in buffered 4% formaldehyde, rinsed briefly in distilled water and transferred directly into a 0.1% solution of Alcian blue to stain overnight (Dingerkus and Uhler, 1977).

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This probably contributes to a fast down-regulation of the fulllength ABI3 in ripe seeds, which is necessary to inhibit the seed maturation program in germinating seeds (Sugliani et al. 2010).

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In the first pass, we display the diffuse lobe of the BRDF through spherical harmonic environment map rendering [Ramamoorthi and Hanrahan 2001].

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Scientometric studies employing bibliometric analyses have been used on many occasions to study scientific specialty profiles (e.g., Rorissa and Yuan 2012; Bajwa et al. 2013; Sanz-Casado et al. 2013) and domain mapping (e.g., White and McCain 1998; Reid and Chen 2007; Liu et al. 2015).

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During this differentiation, the bacterium forms a cytoplasmic region of size half the cell’s length and a large periplasmic region with a small invasion tip (Iwatani et al., 2005).

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This condition has been described variously, as intramural coronary artery, mural coronary artery, coronary artery overbridging, and most commonly myocardial bridging (MB) (Canyigit et al. 2009; Lazoura et al. 2010; Mohlenkamp et al. 2002; Montaudon et al. 2007; Ozbag et al. 2002; Ozbag and Kervancioglu 2004).

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, 2010), and consequently breast biomechanics research has made recommendations to wear a high level of breast support (sports bra) when exercising to reduce breast pain (Bridgman et al., 2010; Scurr et al., 2010; White et al., 2009).

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In addition, human Lpin1 polymorphisms have been associated with numerous metabolic traits including insulin and/or glucose levels (Suviolahti et al., 2006; Loos et al., 2007; Wiedmann et al., 2008), resting metabolic rate (Loos et al.

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GM requires that the input to a neuron is highly variable, and it vanishes for a constant input current (Holt & Koch, 1997).

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Thus, a role for glutamate and excitotoxicity in the direct mechanisms of ALS is appearing tenuous (Martin, 2010a), and the concept has so far failed to bear effective therapeutic fruit after more than 20 years (Rothstein et al., 1992).

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Data on relative testes size were taken from an earlier review (Kappeler 1997a, eight species), gathered from the literature (nine species) and through personal communication with colleagues (six species).

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Only, two studies [3, 56] reported inclusion criteria for entry into the maintenance phase.

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It was demonstrated previously that BPD provides excellent results in long-term weight loss maintenance, resolution or improvement of severe metabolic disorders that are often associated with obesity, and ultimately improved QOL.(7-12,16-22,33-36) Conversely, restrictive procedures have not provided the same satisfactory results in other reports, particularly in controlling type 2 diabetes.

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Samples were applied to a capillary electrophoresis system equipped with an Agilent 6210 time-of-flight mass spectrometer (CE-TOFMS, Agilent Technologies, Santa Clara, CA, USA), as previously described [31].

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[22] References were identified through PubMed for papers published in English between January 1970 and September 2014, which reported population based studies of skin disorders, with specific reference to impetigo or pyoderma prevalence.

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Temporal patterning of EOM myogenesis is, in part, directed by visual- and vestibular-driven eye movements, since maldevelopment of either sensory system impairs EOM development (5, 7).

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While there has been ground-breaking progress in determining the structures of several members of the pLGIC family, from both prokaryotic and eukaryotic origin, an unequivocal assignment of functional states to these conformations has not been achieved (Unwin and Fujiyoshi, 2012; Du et al., 2015; Hilf and Dutzler, 2009, 2008; Sauguet et al., 2013; Bocquet et al., 2009; Miller and Aricescu, 2014; Hassaine et al., 2014; Hibbs and Gouaux, 2011).

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Variations in transcript levels were determined by real time PCR amplification of cDNAs of interest after RT of total mRNAs, as previously detailed (Nadam et al. 2007).

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The systemic nature of this disease is reflected in the involvement of multiple organ systems, including skin, lungs, and vasculature as well as diffuse tissue inflammation and increased risk of atherosclerosis (1).

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1, CD62L, CD44, Streptavidin (BD Biosciences), Gr-1 (in house), and a conjugate of NP to phycoerythrein, made as described (28), were used to identify leukocyte subsets by flow cytometry, with absolute cell numbers determined by live cell count in 0.

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Each fragment was purified and submitted to sequence analysis in the MegaBACE 1000 DNA Analysis System (Amersham Biosciences).

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Regarding the RNA content of EVs, they were found to carry both mRNAs and small RNAs (Valadi et al., 2007; Crescitelli et al., 2013).

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It should be noted that in the absence of BDM, an elevated level of perfusate calcium normally causes NADH levels to decrease because NADH consumption is also stimulated (35).

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Expression values for PIF3 were calculated using the equation 2-ŒîŒîCt, and 18S rRNA served as the control (Livak and Schmittgen, 2001; Pfaffl, 2001).

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For the non-smoothing solution not in H(1)(Ω), a element-local L2 projection technique was presented in [14] to deal with the nonconvex Lipschitz polyhedron with reentrant corners and edges.

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ization properties (4), and their in vivo optimization and therapeutic efficacy in HER2-overexpressing tumor models (27).

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[13] performed splenic artery embolization prior to trans-splenic management of portal vein occlusion in three children.

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(66) we can get
qðxlyÞ ¼ Xk ‘¼1 G xlA‘y þ c‘;s2‘ pð‘lyÞ;
pð‘lyÞ ¼ Gðylm‘;L‘Þa‘Xk ‘¼1 Gðylm‘;L‘Þa‘ ;
ð86Þ
which is a typical case of the alternative mixture-of-expert model (Xu, 1998a; Xu et al., 1995) for mapping y ! x: On the average, we have the regression EðxlyÞ ¼ Pk‘¼1 pð‘lyÞ ðA‘y þ c‘Þ…

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However, rats are able to discriminate harmful food from harmless food by their well-developed olfactory system (Kalat and Rozin 1973; Rana et al. 1975; Bhardwaj and Prakash 1982; Balakrishnan and Alexander 1985).

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A subclone named M5 with enhanced metastatic abilities in liver and a subclone named SCP 51 with enhanced metastatic abilities in liver and lymph node were isolated by in vivo selection of SW480 cells through a process described in our previous studies [18-20].

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The use of bisimilarity in this context is particularly attractive because, as essentially shown in (Hennessy and Milner, 1985), bisimilarity provides an abstraction technique that preserves the truth and falsehood of any formula expressed in the µ-calculus (Kozen, 1983), and hence all CTL∗ (Dam,…

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Consistent with the results of previous studies using poeciliid fish (e.g., Dosen and Montgomerie 2004b; Plath et al. 2008; Wong and McCarthy 2009; Ziege et al. 2009; Jeswiet et al. 2011) and other taxa (e.g., Schwagmeyer and Parker 1990; White and Galef 1999), male guppies here tended to reduce‚Ä¶

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Only some plasma or blood values in field conditions in different areas from Morocco [3], China [4], and Saudi Arabia [5] are available in the literature.

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The previously published evaluation of outcomes took place three months after baseline measurement and the follow-up outcome measurement reported in the present paper was conducted one year after baseline measurement [18,19].

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This is not only an interesting problem by itself [3], but is also a key component to many potential applications including 3D reconstruction [1, 7, 8], graphical navigation [3, 2], and content-based retrieval [9].

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The effects of two osmolytes, sarcosine and sorbitol, were studied for their ability to stabilize hemoglobin against heat-induced dissociation followed by aggregation [55].

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The point probe for fluorescence and reflectance spectroscopy was also evaluated in a Phase II study on a similar number of tissue specimens—and these results were comparable to those obtained by other groups.(54,55,74,75) This investigation helped to identify the causes of measurement variability in the clinical setting (eg, differences in menopausal status), giving information essential for developing effective downstream normalization and analytical approaches.

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In this scenario, actin filament polymerization within the gap between the ER tubule surrounding the mitochondria and the mitochondrial outer membrane (Figure 8A) results in localized pressure that drives mitochondrial constriction to diameters required for Drp1 helix formation (Korobova et al., 2013).

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Taken together with studies on the function of female ornamentation (Lebas 2006; Weiss 2006; Pryke 2007; reviewed in Amundsen & Parn 2006) and song in female songbirds (Ritchison 1983; Catchpole & Slater 1995; Searcy & Yasukawa 1995; Langmore 1998), these results suggest that the processes…

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We and others have applied several treatments for RN, such as anticoagulants, vitamin E, corticosteroids, and surgical resection [2-4].

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…(Xu, 1998a; Xu et al., 1995), as well as normalized RBF nets (Moody & Darken, 1989; Nowlan, 1990; Xu et al., 1994) and its extensions (Xu, 1998a), but also new adaptive algorithms for learning and new criteria for deciding the number of hidden units, experts, and basis functions (Xu, 1998a, 2001b).

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Lithium chloride is an inhibitor to both GSK3α and GSK3β isoforms, which has been shown to increase IL-17-induced gene expression in two previous studies (8, 20).

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For example, we could construct information divergence interpretations of other message-passing algorithms, such as generalized belief propagation (Yedidia et al., 2004), max-product versions of BP and TRW (Wainwright et al., 2005a), Laplace propagation (Smola et al., 2003), and bound propagation…

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Criteria for intracellular identification of the ventral superficial muscle motoneurons have been described in detail (Chapple and Krans 2004; Krans and Chapple 2005).

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For experiments measuring the effect of Sch-28080 and ouabain on pHi recovery in ICs, only basolateral Cl removal was used to differentiate IC types (15, 17).

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Recently, Korayem and Bamdad [4] determined the dynamic load carrying capacity of a typical cable suspended manipulator regarding tensile capacity of cables and actuators torque capacity for a given trajectory in a specified time, and Korayem et al.

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The preparation of plasma membrane and isolation of caveolae were achieved using the methods mentioned above (35, 40).

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