Newsgroup: it.salute
Titolo: Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases.

 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834485/?tool=pmcentrez
 
 
Abstract:
 
The external pH of solid tumors is acidic as a consequence of increased
metabolism of glucose and poor perfusion. Acid pH has been shown to stimulate
tumor cell invasion and metastasis in vitro and in cells before tail vein
injection in vivo. The present study investigates whether inhibition of this
tumor acidity will reduce the incidence of in vivo metastases. Here, we show
that oral NaHCO3 selectively increased the pH of tumors and reduced the
formation of spontaneous metastases in mouse models of metastatic breast cancer.
This treatment regimen was shown to significantly increase the extracellular pH,
but not the intracellular pH, of tumors by 31P magnetic resonance spectroscopy
and the export of acid from growing tumors by fluorescence microscopy of tumors
grown in window chambers. NaHCO3 therapy also reduced the rate of lymph node
involvement, yet did not affect the levels of circulating tumor cells,
suggesting that reduced organ metastases were not due to increased
intravasation. In contrast, NaHCO3 therapy significantly reduced the formation
of hepatic metastases following intrasplenic injection, suggesting that it did
inhibit extravasation and colonization. In tail vein injections of alternative
cancer models, bicarbonate had mixed results, inhibiting the formation of
metastases from PC3M prostate cancer cells, but not those of B16 melanoma.
Although the mechanism of this therapy is not known with certainty, low pH was
shown to increase the release of active cathepsin B, an important matrix
remodeling protease.
 
 
-- 
LoStaff di Simoncini
http://www.drsimoncinicommunity.com/it/
 
lostaf...@doctor.com
 

Il 05/01/20 15:58, LoStaff. ha scritto:

Bibliografia essenziale:
 
     Bicarbonate increases tumor pH and inhibits spontaneous metastases
 
qui ti spiega, ammesso tu capisca qualcosa, il metodo simoncini cmq non 
serve a nulla, è solo pericoloso, come vari casi hanno dimostrato, 
costandogli la RADIAZIONE.
 
https://www.my-personaltrainer.it/alimentazione/bicarbonato-cancro.html
 
 
L'iniezione del bicarbonato per via endovenosa (o parenterale) è 
estremamente pericolosa per tutti gli organi, inclusi quelli sani.
Alcuni studi in corso negli Stati Uniti stanno testando un derivato del 
bicarbonato di sodio, allo scopo di diminuire l'acidità intorno alla 
massa tumorale e studiare se questo rende la chemioterapia più efficace.
 
Questo e altro su: 
https://www.airc.it/cancro/informazioni-tumori/corretta-informazione/bicarbonato
 
-- 
mo_mo 🇮🇹🎸😜😃🎅🙈🙉🙊𝒗𝒆𝒓𝒊𝒇𝒊𝒆𝒅✅👌✨ 🍓
♫ ♬ 🎶🎶 ❤


Certo che paragonare come fonte my-personaltrainer a Pubmed e' come mescolare la
nutella con la merda.


Certo che paragonare come fonte my-personaltrainer a Pubmed e' come mescolare lanutella con la merda.-- LoStaff di Simoncinihttp://
www.drsimoncinicommunity.com/it/lostaf...@doctor.com
 
 
Era un riassunto più alla tua portata. Ma una goccia di limone non
 si sposa bene col bicarbonato?
 
Altro link 
https://www.fondazioneveronesi.it/magazine/articoli/onc
 
ologia/il-cancro-non-si-cura-con-il-bicarbonato
-- 
Mo do
 
Attenti a un fake che spamma in vari ng, morfa con vari nickname
 altrui, fa il fake anche di app e loro short link per rimandare a
 un sito niubbie . qualcosa, con cui io e altri non abbiamo nulla
 a che fare.
 
 
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