Newsgroup: it.politica.internazionale
Titolo: Russian Researchers Develop Tomato Vaccine Against HIV and Hepatitis

Russian Researchers Develop Tomato Vaccine Against HIV and Hepatitis
 
da MosNews
 Genetically modified tomatoes containing edible vaccine are to be used to
challenge two of the world’s most lethal viruses, NewScientist.com
reports. 
The aim is to create affordable vaccines for HIV and the hepatitis B virus
(HBV) that could be easily grown and processed in the countries where they
are most needed. So far, none of the 90 or so potential vaccines against
HIV have proved successful and, though a vaccine already exists for HBV,
it is too expensive to be used by poorer countries.
Rurik Salyaev at the Siberian Institute of Plant Physiology and
Biochemistry in Irkutsk, Russia, and his colleagues used the soil
bacterium Agrobacterium tumefaciens to shuttle a synthetic combination of
HIV and HBV DNA fragments into tomato plants. These include fragments of
genes for various HIV proteins and the gene for an HBV protein called HBV
surface antigen.
The tomato plants then manufacture the proteins and, like the oral polio
vaccine, when the tomatoes are eaten, these proteins prompt the body to
create antibodies against the viruses.
Mice fed a solution containing the tomatoes in powdered form developed
high levels of antibodies in their blood to both viruses. Equally
important, the researchers found antibodies on mucosal surfaces, where the
viruses can gain entry to the body through sexual contact. “That’s where
you want it to be protective,” says Rose Hammond of the US Department of
Agriculture’s Agricultural Research Service in Beltsville, Maryland, which
is collaborating with the Russian researchers.
The results were presented at a meeting of the International Society for
Infectious Diseases in Lisbon, Portugal, last month, by team leader Sergei
Shchelkunov of Russia’s Vector Institute in Koltsovo.
If the tomato-based vaccines work in humans they could be given in tablet
form, since giving people the tomatoes directly would make it difficult to
control how much protein they received.
“You wouldn’t have to refrigerate the vaccine, and you wouldn’t need to
inject it with needles, which pose an infection risk,” says Hammond. These
would be big advantages in poorer countries. “If an oral vaccine worked
out, it would probably be inexpensive and relatively easy to make and
administer,” says Pat Fast, at the International AIDS Vaccine Initiative
in New York. However, an ideal vaccine would trigger production of
protective T-cells as well as antibodies, she says.
Tomatoes are not the first vegetables people have used to make vaccines.
Charles Arntzen of Arizona State University in Tempe has produced potatoes
that stimulate protective antibodies against HBV when eaten raw, although
the recipients had previously been vaccinated against the virus,
potentially masking the effects. Arntzen is awaiting permission to
continue his research
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speriamo bene, sarebbe una buona notizia per frenare la diffusione del
virus , specie nei paesi del Terzo Mondo.
-- 
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 Russian Researchers Develop Tomato Vaccine Against HIV and Hepatitis
ROTFL
Ma da dove becchi ste cazzate? L'Intrepido?
Tb 

 ROTFL
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1) From issue 2558 of New Scientist magazine, 29 June 2006, page 20
2) cazzate? perche'?
 
Ps: sei allergico ai pomodori ?  
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http://www.newscientist.com/channel/health/mg19125584.600.html
il titolo originale però è molto più carino:
"Killer tomatoes[..]"
:)

 wrote:
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Sara' sempre un vero piacere vaccinarlo contro la fesseria a pomodori in 
faccia...
Am.

amalric ha scritto:
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ROTFL!!!!!! russofobo filocollaborazionista dei nazisti, ma se hai paura
della  tua stessa ombra...
