Newsgroup: it.salute.alimentazione
Titolo: carie... una soluzione?

Conoscete questo prodotto? E' in commercio negli Stati Uniti, e tra pochi
mesi (spero) lo sara' anche in Europa
http://www.evoraplus.com/
E' stato brevettato dalla Oragenics
http://www.oragenics.com/
Questa e' la pubblicazione su PubMed del principio attivo
http://www.ncbi.nlm.nih.gov/pubmed/19815843
L'Oragenics e' la casa farmceutica fondata da Jeffrey Hillman
(
http://people.forbes.com/profile/jeffrey-d-hillman/60467
)
uno dei ricercatori piu' attivi nel campo della saute orale.
In pratica e' un alimento probiotico che sostituisce il batterio
streptococco mutans (responsabile della carie) con altri tipi di batteri
innoqui per i nostri denti
E' una cura a che dura 4 settimane e costa meno di 20 dollari... fate voi...
Attualmente non si trova nelle farmacie, ma e' possibile acquistarlo solo
presso farmacie specializzate (se fate una breve ricerca su internet lo
trovere da voi)
°°°°°°°°°°°°°°°°°°°°°°°°°°°°°°°°°°°°°
qui altre info di carattere tecnico:
Oragenics Probiora3 For Oral Health Jan 2010 - Presentation Transcript
Probiotics
Defined as the daily administration of certain live microorganisms in
amounts adequate to confer a health benefit on the host.
Oragenics’ Probiotic Cocktail
S. oralis KJ3
S. uberis KJ2
S. rattus JH145
The Problem
Adults have an average
of 23 decayed and filled
tooth surfaces
5 billion people affected
worldwide
Expenditures for dental care in the US, 2004: $66 billion
Most of these costs are associated with dental caries
Cariogenicity of Parent
and Mutant Strains
Decay caused by lactic acid-producing S. mutans
Lactic acid dissolves the mineral in teeth and the dextran capsule traps the
acid next to the tooth
x
x
x
x
x
x
x
x
Cariogenicity of Parent
and Mutant Strains
Rat infected with acid-producing wild-type strain
Rat infected with JH145
The Problem
Three out of four American adults have some form of periodontal disease
Periodontal disease causes over 70% of tooth loss in adults over the age of
35
The American Dental Association has estimated the spending on professional
periodontal treatment to be nearly $12 billion per year
6-8 species of bacteria cause the disease(S)
Dental-videos.com
http://www.perio.org/consumer/2a.html
Healthy Diseased
S. oralis
S. uberis
Basis for the Negative Interaction
The mechanism of inhibition by S. oralis is production of hydrogen peroxide.
Safety
Confirmed in laboratory animals and humans
All three strains are sensitive to all front-line antibiotics
JH145 (ldh) reversion frequency is unmeasurably low
Efficacy: BID for Four Weeks
Cosmetic Benefits
The peroxide also provides a whitening effect
Decreased production of volatile sulfur-containing compounds
control
treated
Tea and chlorhexidine-stained ceramic
chips treated with probiotic or untreated
Current Status
Adult formulation (EvoraPlus) – Gum and Tooth
Children’s formulation (EvoraKids) – Tooth health
Companion pet formulation (Teddy’s Pride) - Gums
Oragenics
--------------------------------
Inviato via 
http://arianna.libero.it/usenet/

>"Gianni Salveti" 
ha spammato

 ha spammato
e non solo qui...

 
http://www.ncbi.nlm.nih.gov/pubmed/19815843
Non è la pubblicazione del principio attivo, è uno studio sulla sua 
sicurezza basato sui ratti!!