A system for identification and denervation of a lung nerve, comprising: a memory configured to receive a first set of images of at least a portion of a lung displaying symptoms of lung disease; a processor ; a display ; an ultrasound imaging device ; and a non-invasive treatment device ; an application executable by the processor to generate a three dimensional model of at least the portion of the lung captured in the first set of images and to display on the display a user interface enabling a user to review the first set of images and the three dimensional model to locate the portion of the lung captured in the first set of images displaying symptoms of lung disease, a pathway planning module executable by the processor to guide a user through a series of steps to develop , based on the three-dimensional model, and display on the display , a pathway plan to the portion of the lung displaying symptoms of lung disease, wherein, upon insertion of the ultrasound imaging device into the patient, the ultrasound imaging device can be made to follow the pathway to image the portion of the lung displaying symptoms of lung disease, an image registration application executable by the processor to register the ultrasound images of the portion of the lung displaying symptoms of lung disease to the first set of images to produce an enhanced resolution combined image set, the processor being configured to generate an enhanced three dimensional model using the enhanced resolution combined image set to aid the clinician in locating a target nerve proximate the said portion of the lung, and a treatment plan application executable by the processor for generating a treatment plan developed from the enhanced three dimensional model; wherein the treatment device is configured to non-invasively denervate the target nerve based on the treatment plan such that the function of the said portion of the lung is affected. a memory configured to receive a first set of images of at least a portion of a lung displaying symptoms of lung disease; a processor ; a display ; an ultrasound imaging device ; and a non-invasive treatment device ; an application executable by the processor to generate a three dimensional model of at least the portion of the lung captured in the first set of images and to display on the display a user interface enabling a user to review the first set of images and the three dimensional model to locate the portion of the lung captured in the first set of images displaying symptoms of lung disease, a pathway planning module executable by the processor to guide a user through a series of steps to develop , based on the three-dimensional model, and display on the display , a pathway plan to the portion of the lung displaying symptoms of lung disease, wherein, upon insertion of the ultrasound imaging device into the patient, the ultrasound imaging device can be made to follow the pathway to image the portion of the lung displaying symptoms of lung disease, an image registration application executable by the processor to register the ultrasound images of the portion of the lung displaying symptoms of lung disease to the first set of images to produce an enhanced resolution combined image set, the processor being configured to generate an enhanced three dimensional model using the enhanced resolution combined image set to aid the clinician in locating a target nerve proximate the said portion of the lung, and a treatment plan application executable by the processor for generating a treatment plan developed from the enhanced three dimensional model; wherein the treatment device is configured to non-invasively denervate the target nerve based on the treatment plan such that the function of the said portion of the lung is affected. <EOS>