mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of formula (I), or the tautomers or pharmacologically acceptable acid addition salts thereof, wherein R 1 is selected from C 1 -C 4 -alkyl, 2-(2-hydroxyethyloxy)-ethyl, tetrahydrofur-2-ylmethyl, tetrahydropyran-4-ylmethyl, pyridine-3-ylmethyl and wherein denotes the point of attachment; R 2 is selected from C 1 -C 4 -alkyl, 2-(2-hydroxyethyloxy)-ethyl, tetrahydrofur-2-ylmethyl, tetrahydropyran-4-ylmethyl, pyridine-3-ylmethyl, and wherein denotes the point of attachment; provided that at least one of R 1 and R 2 is different from C 1 -C 4 -alkyl and 2-(2-hydroxyethyloxy)ethyl, and wherein one of R 3 and R 4 is selected from a substituent of formula -O-CH 2 -C(O)NR b R c , wherein NR b R c are selected from dimethylamino, wherein denotes the point of attachment; and the remaining one of R 3 or R 4 is H; X is Cl or Br; and Z - is chloride, bromide, iodide, hydroxide, hydrogensulfate, sulfate, nitrate, phosphate, formate, acetate, trifluoroacetate, fumarate, citrate, tartrate, oxalate, succinate, mandelate, methanesulfonate or p-toluenesulfonate; or Z - may be absent if the remaining compound of formula (I) carries at least one negatively charged substituent R 3 or R 4 . R 1 is selected from C 1 -C 4 -alkyl, 2-(2-hydroxyethyloxy)-ethyl, tetrahydrofur-2-ylmethyl, tetrahydropyran-4-ylmethyl, pyridine-3-ylmethyl and wherein denotes the point of attachment; R 2 is selected from C 1 -C 4 -alkyl, 2-(2-hydroxyethyloxy)-ethyl, tetrahydrofur-2-ylmethyl, tetrahydropyran-4-ylmethyl, pyridine-3-ylmethyl, and wherein denotes the point of attachment; provided that at least one of R 1 and R 2 is different from C 1 -C 4 -alkyl and 2-(2-hydroxyethyloxy)ethyl, and wherein one of R 3 and R 4 is selected from a substituent of formula -O-CH 2 -C(O)NR b R c , wherein NR b R c are selected from dimethylamino, wherein denotes the point of attachment; and the remaining one of R 3 or R 4 is H; X is Cl or Br; and Z - is chloride, bromide, iodide, hydroxide, hydrogensulfate, sulfate, nitrate, phosphate, formate, acetate, trifluoroacetate, fumarate, citrate, tartrate, oxalate, succinate, mandelate, methanesulfonate or p-toluenesulfonate; or Z - may be absent if the remaining compound of formula (I) carries at least one negatively charged substituent R 3 or R 4 . X is Cl or Br; and Z - is chloride, bromide, iodide, hydroxide, hydrogensulfate, sulfate, nitrate, phosphate, formate, acetate, trifluoroacetate, fumarate, citrate, tartrate, oxalate, succinate, mandelate, methanesulfonate or p-toluenesulfonate; or Z - may be absent if the remaining compound of formula (I) carries at least one negatively charged substituent R 3 or R 4 .
An intervertebral disc prosthesis insertion assembly comprising: an insertion adapter having a coupler for a demountable insertion tool body and actuator means ; and an intervertebral disc prosthesis releasably retained by the insertion adapter via the actuator means , wherein the insertion adapter has at least one retainer that engages a recess and/or post of the intervertebral disc prosthesis , wherein the actuator means release the intervertebral prosthesis from the insertion adapter and comprise spring-loaded arms, tangs, shanks or other actuating means , wherein the actuator means actuate with respect to one another at a pivot located between a first end and a second, opposite end of the actuator means , and wherein the coupler is positioned between the first end and the second, opposite end of the actuator means . an insertion adapter having a coupler for a demountable insertion tool body and actuator means ; and an intervertebral disc prosthesis releasably retained by the insertion adapter via the actuator means , wherein the insertion adapter has at least one retainer that engages a recess and/or post of the intervertebral disc prosthesis , wherein the actuator means release the intervertebral prosthesis from the insertion adapter and comprise spring-loaded arms, tangs, shanks or other actuating means , wherein the actuator means actuate with respect to one another at a pivot located between a first end and a second, opposite end of the actuator means , and wherein the coupler is positioned between the first end and the second, opposite end of the actuator means .
A method of analyzing performance of a processing system, the method comprising: identifying a first transaction as a transaction to be monitored, at a first trace point of the processing system, based on detecting the first transaction at least a threshold number of times at the first trace point; associating a first trace tag identifier with the first transaction, at the first trace point; and identifying the first transaction at one or more other trace points of the processing system based on the first trace tag identifier; determining time stamps at which the first transaction is identified at the first trace point and the one or more other trace points; and determining trace information for the first transaction from the time stamps. identifying a first transaction as a transaction to be monitored, at a first trace point of the processing system, based on detecting the first transaction at least a threshold number of times at the first trace point; associating a first trace tag identifier with the first transaction, at the first trace point; and identifying the first transaction at one or more other trace points of the processing system based on the first trace tag identifier; determining time stamps at which the first transaction is identified at the first trace point and the one or more other trace points; and determining trace information for the first transaction from the time stamps.
Process for the electroporation of cells, wherein the cells comprise sugar beet cells, wherein the electroporation is done in a reactor system, comprising: • a reactor chamber having a length and a width, whereby the reactor chamber contains a central section along its length, and whereby the length of the reactor chamber is at least 1.5 times the width of the reactor chamber; • a first pulse generator to which two electrodes A1 and A2 are connected, whereby the electrodes A1 and A2 are located in the reactor chamber in the central section and such that they are, when measured in the length direction, at least a distance equalling half the width of the reactor chamber apart; • a second pulse generator to which two electrodes B1 and B2 are connected, whereby the electrodes B1 and B2 are located in the reactor chamber in the central section and such that they are, when measured in the length direction, at least a distance equalling half the width of the reactor chamber apart, • whereby the electrodes are shaped and placed such that the electrical field in at least the central section is substantially homogeneous, whereby the field lines run in essentially the length direction and whereby the field strength in the central section lies between 0.1 and 20 kV/cm. • a reactor chamber having a length and a width, whereby the reactor chamber contains a central section along its length, and whereby the length of the reactor chamber is at least 1.5 times the width of the reactor chamber; • a first pulse generator to which two electrodes A1 and A2 are connected, whereby the electrodes A1 and A2 are located in the reactor chamber in the central section and such that they are, when measured in the length direction, at least a distance equalling half the width of the reactor chamber apart; • a second pulse generator to which two electrodes B1 and B2 are connected, whereby the electrodes B1 and B2 are located in the reactor chamber in the central section and such that they are, when measured in the length direction, at least a distance equalling half the width of the reactor chamber apart, • whereby the electrodes are shaped and placed such that the electrical field in at least the central section is substantially homogeneous, whereby the field lines run in essentially the length direction and whereby the field strength in the central section lies between 0.1 and 20 kV/cm.
A foam product comprising: a foam core having a top surface , a bottom surface , and a periphery ; an outer skin having an outer surface , an inner surface , and a periphery , wherein the inner surface of the outer skin is laminated onto the top surface of the foam core ; a cross-linked foam sheet having a top surface , a bottom surface , and a periphery , wherein the top surface of the cross-linked foam sheet is laminated onto the bottom surface of the foam core ; a non cross-linked foam sheet having a top surface and a bottom surface , wherein the top surface of the non cross-linked foam sheet is laminated onto the bottom surface of the cross-linked foam sheet ; and a non foam plastic plate laminated onto the bottom surface of the non cross-linked foam sheet . a foam core having a top surface , a bottom surface , and a periphery ; an outer skin having an outer surface , an inner surface , and a periphery , wherein the inner surface of the outer skin is laminated onto the top surface of the foam core ; a cross-linked foam sheet having a top surface , a bottom surface , and a periphery , wherein the top surface of the cross-linked foam sheet is laminated onto the bottom surface of the foam core ; a non cross-linked foam sheet having a top surface and a bottom surface , wherein the top surface of the non cross-linked foam sheet is laminated onto the bottom surface of the cross-linked foam sheet ; and a non foam plastic plate laminated onto the bottom surface of the non cross-linked foam sheet .
A sweat sensor device for sensing sweat on the skin comprising: one or more solute-specific sweat sensors (420, 520, 620, 801, 1120, 1301, 1520, 1721-4); and a volume-reducing component that provides a volume-reduced pathway for sweat between the one or more sweat sensors (420, 520, 620, 801, 1120, 1301, 1520, 1721-4) and sweat glands when said device is positioned on said skin, wherein one or more sweat sensors (420, 520, 620, 801, 1120, 1301, 1520, 1721-4) has a sampling interval when sensing sweat and the volume-reduced pathway decreases the sampling interval of the one or more sweat sensors (420, 520, 620, 801, 1120, 1301, 1520, 1721-4), wherein the volume-reducing component is a volume-reducing material ; and characterised in that the volume-reducing material is configured to self-align with sweat pores and/or is configured to be displaceable by sweat to form part of the volume-reduced pathway within the volume reducing material. one or more solute-specific sweat sensors (420, 520, 620, 801, 1120, 1301, 1520, 1721-4); and a volume-reducing component that provides a volume-reduced pathway for sweat between the one or more sweat sensors (420, 520, 620, 801, 1120, 1301, 1520, 1721-4) and sweat glands when said device is positioned on said skin, wherein one or more sweat sensors (420, 520, 620, 801, 1120, 1301, 1520, 1721-4) has a sampling interval when sensing sweat and the volume-reduced pathway decreases the sampling interval of the one or more sweat sensors (420, 520, 620, 801, 1120, 1301, 1520, 1721-4), wherein the volume-reducing component is a volume-reducing material ; and characterised in that the volume-reducing material is configured to self-align with sweat pores and/or is configured to be displaceable by sweat to form part of the volume-reduced pathway within the volume reducing material.
Apparatus for monitoring a telecommunication network comprising one or more telecommunication channels , the apparatus comprising means (6, 7, P) configured for: - designing (S1, S2, S3) a neural network configured for determining an impairment type of a telecommunication channel as a function of a channel frequency response of said telecommunication channel , - training (S5) said neural network based on training data specifying, for respective telecommunication channels, a channel frequency response and an associated impairment type, characterized in that said neural network is a convolutional neural network, wherein designing the convolutional neural network comprises selecting at least one of a number of convolutional layers, a number of filters and/or a size of filters for respective convolutional layers as a function of analysis results of channel frequency responses for a plurality of telecommunication channels. - designing (S1, S2, S3) a neural network configured for determining an impairment type of a telecommunication channel as a function of a channel frequency response of said telecommunication channel , - training (S5) said neural network based on training data specifying, for respective telecommunication channels, a channel frequency response and an associated impairment type,
A method by a user equipment, UE, configured to transmit packet data units, PDUs, by a first Radio Link Control, RLC, entity via a first uplink transmission path and/or by a second RLC entity via a second uplink transmission path, the method comprising: determining a total amount of data volume buffered for PDU transmission, wherein the total amount of data volume comprises Packet Data Convergence Protocol, PDCP, data volume and RLC data volume pending for initial transmission in the two RLC entities; reporting the PDCP data volume to at least the first uplink transmission path, based on whether the total amount of data volume meets or exceeds a first threshold, wherein the reporting comprises: in response to determining that the total amount of data volume meets or exceeds the first threshold, indicating the PDCP data volume to both the first uplink transmission path and the second uplink transmission path, and in response to determining that the total amount of data volume does not meet the first threshold, indicating the PDCP data volume to only the first uplink transmission path; and in response to determining that the total amount of data volume does not meet the first threshold, submitting the PDCP data volume only to the first RLC entity. determining a total amount of data volume buffered for PDU transmission, wherein the total amount of data volume comprises Packet Data Convergence Protocol, PDCP, data volume and RLC data volume pending for initial transmission in the two RLC entities; reporting the PDCP data volume to at least the first uplink transmission path, based on whether the total amount of data volume meets or exceeds a first threshold, wherein the reporting comprises: in response to determining that the total amount of data volume meets or exceeds the first threshold, indicating the PDCP data volume to both the first uplink transmission path and the second uplink transmission path, and in response to determining that the total amount of data volume does not meet the first threshold, indicating the PDCP data volume to only the first uplink transmission path; and in response to determining that the total amount of data volume meets or exceeds the first threshold, indicating the PDCP data volume to both the first uplink transmission path and the second uplink transmission path, and in response to determining that the total amount of data volume does not meet the first threshold, indicating the PDCP data volume to only the first uplink transmission path; and
A quantum system comprising: a microwave transmitter configured to provide a continuous microwave tone; a qubit configured such that a portion of an energy spectrum of the qubit is responsive to an applied flux, the qubit having an inductive element responsive to the continuous microwave tone to produce a Rabi oscillation within the qubit; a flux source configured to apply a flux to the qubit; and a system control characterized in being configured to: control the flux source as to selectively apply flux to the qubit, such that a qubit resonance frequency associated with the energy spectrum of the qubit is selectively tuned to a frequency of the Rabi oscillation; and tune the qubit resonance frequency to the frequency of the Rabi oscillation for a predetermined period of time equal to a ratio of a desired angle of the X rotation to the frequency of the Rabi oscillation, such that an X rotation of the qubit state is achieved. a microwave transmitter configured to provide a continuous microwave tone; a qubit configured such that a portion of an energy spectrum of the qubit is responsive to an applied flux, the qubit having an inductive element responsive to the continuous microwave tone to produce a Rabi oscillation within the qubit; a flux source configured to apply a flux to the qubit; and a system control characterized in being configured to: control the flux source as to selectively apply flux to the qubit, such that a qubit resonance frequency associated with the energy spectrum of the qubit is selectively tuned to a frequency of the Rabi oscillation; and tune the qubit resonance frequency to the frequency of the Rabi oscillation for a predetermined period of time equal to a ratio of a desired angle of the X rotation to the frequency of the Rabi oscillation, such that an X rotation of the qubit state is achieved. control the flux source as to selectively apply flux to the qubit, such that a qubit resonance frequency associated with the energy spectrum of the qubit is selectively tuned to a frequency of the Rabi oscillation; and tune the qubit resonance frequency to the frequency of the Rabi oscillation for a predetermined period of time equal to a ratio of a desired angle of the X rotation to the frequency of the Rabi oscillation, such that an X rotation of the qubit state is achieved.
An enveloping body for at least partially recording a contour of a limb, wherein the enveloping body has a base body , wherein the enveloping body has at least one sensor that is configured to record measurement data which can be used to determine a distance and/or relative position between two points in or on the base body characterized in that the enveloping body is a prosthetic liner and the base body is made of a liner material.
An isolated nucleic acid molecule comprising a polynucleotide encoding a hairpin ribonucleic acid (hpRNA) molecule with a stem and loop structure that is capable of inhibiting the expression of an endogenous target gene in a cell of a coleopteran insect upon ingestion, wherein the polynucleotide is operably linked to a heterologous promoter, and wherein the polynucleotide comprises: a first nucleotide sequence encoding a polyribonucleotide of the hpRNA molecule, wherein the first nucleotide sequence is selected from the group consisting of at least 50 contiguous nucleotides of SEQ ID NO:84, the complement of at least 50 contiguous nucleotides of SEQ ID NO:84, at least 50 contiguous nucleotides of SEQ ID NO:86, the complement of at least 50 contiguous nucleotides of SEQ ID NO:86, at least 50 contiguous nucleotides of SEQ ID NO:88, the complement of at least 50 contiguous nucleotides of SEQ ID NO:88, at least 50 contiguous nucleotides of SEQ ID NO:93 and the complement of at least 50 contiguous nucleotides of SEQ ID NO:93; a second nucleotide sequence encoding a polyribonucleotide of the hpRNA molecule; and a third nucleotide sequence encoding a polyribonucleotide of the hpRNA molecule, wherein the third nucleotide sequence is substantially the reverse complement of the first nucleotide sequence, such that the polyribonucleotides encoded by the first and the third nucleotide sequences hybridize in a stem structure of the hpRNA molecule, wherein a loop structure of the hpRNA molecule comprises the polyribonucleotide encoded by the second nucleotide sequence. a first nucleotide sequence encoding a polyribonucleotide of the hpRNA molecule, wherein the first nucleotide sequence is selected from the group consisting of at least 50 contiguous nucleotides of SEQ ID NO:84, the complement of at least 50 contiguous nucleotides of SEQ ID NO:84, at least 50 contiguous nucleotides of SEQ ID NO:86, the complement of at least 50 contiguous nucleotides of SEQ ID NO:86, at least 50 contiguous nucleotides of SEQ ID NO:88, the complement of at least 50 contiguous nucleotides of SEQ ID NO:88, at least 50 contiguous nucleotides of SEQ ID NO:93 and the complement of at least 50 contiguous nucleotides of SEQ ID NO:93; a second nucleotide sequence encoding a polyribonucleotide of the hpRNA molecule; and a third nucleotide sequence encoding a polyribonucleotide of the hpRNA molecule, wherein the third nucleotide sequence is substantially the reverse complement of the first nucleotide sequence, such that the polyribonucleotides encoded by the first and the third nucleotide sequences hybridize in a stem structure of the hpRNA molecule, wherein a loop structure of the hpRNA molecule comprises the polyribonucleotide encoded by the second nucleotide sequence.
An optical network unit, ONU, comprising: a passive optical network, PON, interface configured to communicate using physical layer operations, administration, and maintenance , PLOAM, messages ; and a processor coupled to the PON interface, characterized in that the processor is configured to: receive a PLOAM reset message comprising a reset level with the reset level comprising an instruction for the ONU to reset a management information base, MIB, to an initial configuration; and reset the MIB of the ONU according to the reset level. a passive optical network, PON, interface configured to communicate using physical layer operations, administration, and maintenance , PLOAM, messages ; and a processor coupled to the PON interface, characterized in that the processor is configured to: receive a PLOAM reset message comprising a reset level with the reset level comprising an instruction for the ONU to reset a management information base, MIB, to an initial configuration; and reset the MIB of the ONU according to the reset level. receive a PLOAM reset message comprising a reset level with the reset level comprising an instruction for the ONU to reset a management information base, MIB, to an initial configuration; and reset the MIB of the ONU according to the reset level.