mhurhangee/patent-ind-claim-en huggingface dataset:
An adeno-associated virus (AAV) vector comprising a promoter operably linked to a nucleic acid sequence that encodes an anti-IgE antibody or antigen binding fragment thereof, for use in inhibiting or reducing an immune response or allergic reaction to an allergen in a mammal, wherein the nucleic acid sequence encodes an anti-IgE antibody or antigen binding fragment thereof, wherein the antibody or antigen-binding fragment thereof comprises a heavy chain polypeptide comprising three complementarity determining regions (CDRs), wherein CDR-H1 comprises the nucleic acid sequence of SEQ ID NO: 1, CDR-H2 comprises the nucleic acid sequence of SEQ ID NO: 2, and CDR-H3 comprises the nucleic acid sequence of SEQ ID NO: 3; and a light chain polypeptide comprising three CDRs, wherein CDR-L1 comprises the nucleic acid sequence of SEQ ID NO: 4, CDR-L2 comprises the nucleic acid sequence of SEQ ID NO: 5, and CDR-L3 comprises the nucleic acid sequence of SEQ ID NO: 6. wherein the nucleic acid sequence encodes an anti-IgE antibody or antigen binding fragment thereof, wherein the antibody or antigen-binding fragment thereof comprises a heavy chain polypeptide comprising three complementarity determining regions (CDRs), wherein CDR-H1 comprises the nucleic acid sequence of SEQ ID NO: 1, CDR-H2 comprises the nucleic acid sequence of SEQ ID NO: 2, and CDR-H3 comprises the nucleic acid sequence of SEQ ID NO: 3; and a light chain polypeptide comprising three CDRs, wherein CDR-L1 comprises the nucleic acid sequence of SEQ ID NO: 4, CDR-L2 comprises the nucleic acid sequence of SEQ ID NO: 5, and CDR-L3 comprises the nucleic acid sequence of SEQ ID NO: 6.
Protection circuitry for an implantable pulse generator, IPG, of a neurostimulation system, the protection circuitry coupled to an IPG ground , a plurality of electrodes , and an IPG case , and operable to protect IPG stimulation and sensing circuitry from damage during electrostatic discharge and cardiac defibrillation, and to mitigate unintended stimulation during electromagnetic interference, the protection circuitry comprising: an IPG ground connection; a plurality of protection Zener diodes , wherein one of the protection Zener diodes is electrically coupled between the IPG case and a float Zener diode , and wherein the remaining protection Zener diodes are electrically coupled between the plurality of electrodes and the float Zener diode; and the float Zener diode electrically coupled between the plurality of protection Zener diodes and the IPG ground. an IPG ground connection; a plurality of protection Zener diodes , wherein one of the protection Zener diodes is electrically coupled between the IPG case and a float Zener diode , and wherein the remaining protection Zener diodes are electrically coupled between the plurality of electrodes and the float Zener diode; and the float Zener diode electrically coupled between the plurality of protection Zener diodes and the IPG ground.
A shopping trolley comprising: a basket having first and second side walls (22 and 23), first and second end walls (20 and 21) and a base wall ; first and second front legs (26 and 27), each having a wheel on a lower end thereof; and first and second rear legs (28 and 29), each having a wheel on a lower end thereof; wherein the first and second front legs (26 and 27) are rotatable from an extended position, in which the first and second front legs (26 and 27) extend downwardly from adjacent a front of the basket , to a collapsed position, in which the first and second front legs (26 and 27) are located adjacent outer sides of the first and second side walls (22 and 23) of the basket respectively, and the rear legs (28 and 29) are rotatable from an extended position, in which the first and second rear legs (28 and 29) extend downwardly from adjacent a rear of the basket , to a collapsed position, in which portions of the first and second rear legs (28 and 29) are located adjacent and above upper edges of the first and second side walls (22 and 23) of the basket respectively. a basket having first and second side walls (22 and 23), first and second end walls (20 and 21) and a base wall ; first and second front legs (26 and 27), each having a wheel on a lower end thereof; and first and second rear legs (28 and 29), each having a wheel on a lower end thereof; wherein the first and second front legs (26 and 27) are rotatable from an extended position, in which the first and second front legs (26 and 27) extend downwardly from adjacent a front of the basket , to a collapsed position, in which the first and second front legs (26 and 27) are located adjacent outer sides of the first and second side walls (22 and 23) of the basket respectively, and the rear legs (28 and 29) are rotatable from an extended position, in which the first and second rear legs (28 and 29) extend downwardly from adjacent a rear of the basket , to a collapsed position, in which portions of the first and second rear legs (28 and 29) are located adjacent and above upper edges of the first and second side walls (22 and 23) of the basket respectively.
A computer-implemented method , comprising: obtaining , by a first computing device , an audio input signal for an audio communication session with a second computing device using audio data captured by a microphone of the first computing device ; analyzing , by the first computing device , the audio input signal to detect a speech input by a first user associated with the first computing device ; determining , by the first computing device , a detection period duration from when the audio input signal was obtained until the analyzing has completed; transmitting , from the first computing device and to the second computing device , (i) a portion of the audio input signal beginning at a start of the speech input and (ii) the detection period duration; in response to receiving, at the second computing device , the portion of the audio input signal and the detection period duration, accelerating playback, by the second computing device , of the portion of the audio input signal to compensate for the detection period duration; analyzing , by the first computing device , the audio input signal to detect an end of the speech input by the first user; and terminating transmission, from the first computing device to the second computing device , of the portion of the audio input signal at a point corresponding to the detected end of the speech input by the first user. obtaining , by a first computing device , an audio input signal for an audio communication session with a second computing device using audio data captured by a microphone of the first computing device ; analyzing , by the first computing device , the audio input signal to detect a speech input by a first user associated with the first computing device ; determining , by the first computing device , a detection period duration from when the audio input signal was obtained until the analyzing has completed; transmitting , from the first computing device and to the second computing device , (i) a portion of the audio input signal beginning at a start of the speech input and (ii) the detection period duration; in response to receiving, at the second computing device , the portion of the audio input signal and the detection period duration, accelerating playback, by the second computing device , of the portion of the audio input signal to compensate for the detection period duration; analyzing , by the first computing device , the audio input signal to detect an end of the speech input by the first user; and terminating transmission, from the first computing device to the second computing device , of the portion of the audio input signal at a point corresponding to the detected end of the speech input by the first user.
Process for the regeneration of an adsorber comprising the steps a) to e): a) converting a stream (S2) comprising at least one alkane from liquid phase into gaseous phase, b) regenerating the adsorber by contact with gaseous stream (S2) in a range of 230 to 270 °C, c) cooling the adsorber by contact with gaseous stream (S2) obtained in step a) to a temperature in a range of 90 to 150 °C, d) optionally cooling the adsorber to a temperature below 80 °C by contact with liquid stream (S2) without prior conversion into gaseous phase, e) recycling of the outflow (S2*) of the adsorber as obtained in step c) and/or optionally in step d), wherein the outflow (S2*) is at least partially recycled to at least one of the steps a) to d), wherein the process comprises a further step f): f) hydrogenation of a stream (S1) comprising at least one alkane and at least one olefin, carried out prior to step a), to obtain a liquid stream (S2) comprising at least one alkane and a reduced amount of at least one olefin compared to the amount of stream (S1), wherein in step f), the stream (S1) comprises at least 96 wt-% butane and not more than 4 wt-% butene and wherein the stream (S2) comprises at least 99 wt-% butane and not more than 1000 wt-ppm butene. a) converting a stream (S2) comprising at least one alkane from liquid phase into gaseous phase, b) regenerating the adsorber by contact with gaseous stream (S2) in a range of 230 to 270 °C, c) cooling the adsorber by contact with gaseous stream (S2) obtained in step a) to a temperature in a range of 90 to 150 °C, d) optionally cooling the adsorber to a temperature below 80 °C by contact with liquid stream (S2) without prior conversion into gaseous phase, e) recycling of the outflow (S2*) of the adsorber as obtained in step c) and/or optionally in step d), wherein the outflow (S2*) is at least partially recycled to at least one of the steps a) to d),
A method for managing notifications for a first electronic device , the method comprising: receiving, by a first electronic device, data; and generating, by the first electronic device, a first notification based on the received data; transmitting, by the first electronic device, a first information relating to the received data to a second electronic device, the first information being for displaying a second notification at the second electronic device; and if the first electronic device receives a user input with regard to the first notification, transmitting, by the first electronic device, a second information relating to the user input to the second electronic device, the second information being for stopping the displaying of the second notification. receiving, by a first electronic device, data; and generating, by the first electronic device, a first notification based on the received data; transmitting, by the first electronic device, a first information relating to the received data to a second electronic device, the first information being for displaying a second notification at the second electronic device; and if the first electronic device receives a user input with regard to the first notification, transmitting, by the first electronic device, a second information relating to the user input to the second electronic device, the second information being for stopping the displaying of the second notification.
A single-molecule detection system, comprising: a) a movable light coupler ; b) a waveguide comprising: a core layer , and a first cladding layer and a second cladding layer sandwiching the core layer , wherein at least one adapter site for the movable light coupler is formed in at least the first cladding layer ; and c) a light detector , wherein the movable light coupler is able to localize a target molecule at the at least one adapter site , wherein the at least one adapter site for the movable light coupler is a nanowell, and the movable light coupler is a nano-scale particle, characterised in that : the detection system comprises an integrated component comprising the light detector , the at least one adapter site , and the waveguide ; the refractive index of the core layer is higher than the refractive indices of the first cladding layer and the second cladding layer ; the refractive index of the movable light coupler is greater than the refractive index of the first cladding layer of the waveguide, and the movable light coupler is able to couple an evanescent light field induced near the surface of the core layer in the at least one adapter site by a light wave propagating along the core layer , whereby an effective excitation zone forms around the surface of the movable light coupler . a) a movable light coupler ; b) a waveguide comprising: a core layer , and a first cladding layer and a second cladding layer sandwiching the core layer , wherein at least one adapter site for the movable light coupler is formed in at least the first cladding layer ; and a core layer , and a first cladding layer and a second cladding layer sandwiching the core layer , wherein at least one adapter site for the movable light coupler is formed in at least the first cladding layer ; and c) a light detector , wherein the movable light coupler is able to localize a target molecule at the at least one adapter site , wherein the at least one adapter site for the movable light coupler is a nanowell, and the movable light coupler is a nano-scale particle, the detection system comprises an integrated component comprising the light detector , the at least one adapter site , and the waveguide ; the refractive index of the core layer is higher than the refractive indices of the first cladding layer and the second cladding layer ; the refractive index of the movable light coupler is greater than the refractive index of the first cladding layer of the waveguide, and the movable light coupler is able to couple an evanescent light field induced near the surface of the core layer in the at least one adapter site by a light wave propagating along the core layer , whereby an effective excitation zone forms around the surface of the movable light coupler .
Electrohydrostatic actuator system comprising: a variable-volume and/or variable-speed hydraulic machine driven by an electric motor , for providing a volumetric flow of a hydraulic fluid; a differential cylinder with a piston end and a ring end ; at least one pre-pressurizing source ; wherein the actuator system has a closed hydraulic circuit and, during operation, the hydraulic fluid in the hydraulic circuit is pressurized by means of the hydraulic machine and/or the pre-pressurizing source , and wherein the differential cylinder provides the operating modes of a power traverse and a rapid traverse, and wherein an expansion reservoir is connected to the piston end of the differential cylinder via a first valve to compensate for a volume of the hydraulic fluid in the closed hydraulic circuit , wherein a second valve connects the piston end to the pre-pressurizing source or to the expansion reservoir , characterized in that the second valve is designed as a proportional valve . a variable-volume and/or variable-speed hydraulic machine driven by an electric motor , for providing a volumetric flow of a hydraulic fluid; a differential cylinder with a piston end and a ring end ; at least one pre-pressurizing source ; wherein the actuator system has a closed hydraulic circuit and, during operation, the hydraulic fluid in the hydraulic circuit is pressurized by means of the hydraulic machine and/or the pre-pressurizing source , and wherein the differential cylinder provides the operating modes of a power traverse and a rapid traverse, and wherein an expansion reservoir is connected to the piston end of the differential cylinder via a first valve to compensate for a volume of the hydraulic fluid in the closed hydraulic circuit , wherein a second valve connects the piston end to the pre-pressurizing source or to the expansion reservoir , characterized in that the second valve is designed as a proportional valve .
A non-aqueous electrolyte secondary battery having a power generating element including: a positive electrode in which a positive electrode active material layer including a positive electrode active material is formed on a surface of a positive electrode current collector; a negative electrode in which a negative electrode active material layer including a negative electrode active material is formed on a surface of a negative electrode current collector; and an electrolyte layer in which a separator is impregnated with an electrolyte solution, wherein the negative electrode active material includes a Si material that contains silicon and is capable of insertion and removal of lithium ions, the electrolyte solution contains lithium bis(fluorosulfonyl)imide and an inorganic lithium salt other than the lithium bis(fluorosulfonyl)imide, a ratio of a concentration in mol/L of the lithium bis(fluorosulfonyl)imide with respect to a concentration in mol/L of the inorganic lithium salt in the electrolyte solution is 1 or less, and the concentration of the inorganic lithium salt in the electrolyte solution is 1.0 to 2.0 mol/L, and wherein the negative electrode active material in the negative electrode active material layer is not bound by a binder. a positive electrode in which a positive electrode active material layer including a positive electrode active material is formed on a surface of a positive electrode current collector; a negative electrode in which a negative electrode active material layer including a negative electrode active material is formed on a surface of a negative electrode current collector; and an electrolyte layer in which a separator is impregnated with an electrolyte solution, wherein the negative electrode active material includes a Si material that contains silicon and is capable of insertion and removal of lithium ions, the electrolyte solution contains lithium bis(fluorosulfonyl)imide and an inorganic lithium salt other than the lithium bis(fluorosulfonyl)imide, a ratio of a concentration in mol/L of the lithium bis(fluorosulfonyl)imide with respect to a concentration in mol/L of the inorganic lithium salt in the electrolyte solution is 1 or less, and the concentration of the inorganic lithium salt in the electrolyte solution is 1.0 to 2.0 mol/L, and wherein the negative electrode active material in the negative electrode active material layer is not bound by a binder.
Compensating clutch for offset-compensating connection of two shafts, in particular for use in a drive train of a rail vehicle, having a first connecting flange for connection to a drive shaft, having at least one first elastic compensating element which is connected to the first connecting flange , having a second connecting flange for connection to a driven shaft, having at least one second elastic compensating element which is connected to the second connecting flange , and having a middle piece which is arranged between the first and the second elastic compensating element , wherein the middle piece has at least one first middle-piece element and one second middle-piece element , which are separably connected to one another, and wherein, on the first middle-piece element and on the second middle-piece element , there are arranged in each case multiple force action points for connection to the in each case assigned elastic compensating element , wherein a rib with an axially extending height is arranged in each case between two adjacent force action points , wherein the height of each rib varies from a force action point to an adjacent force action point , characterized in that the height of a rib decreases from a force action point to a circumferentially adjacent force action point , and in that the height of an adjacent rib increases again from the circumferentially adjacent force action point to the next force action point . having a first connecting flange for connection to a drive shaft, having at least one first elastic compensating element which is connected to the first connecting flange , having a second connecting flange for connection to a driven shaft, having at least one second elastic compensating element which is connected to the second connecting flange , and having a middle piece which is arranged between the first and the second elastic compensating element , wherein the middle piece has at least one first middle-piece element and one second middle-piece element , which are separably connected to one another, and wherein, on the first middle-piece element and on the second middle-piece element , there are arranged in each case multiple force action points for connection to the in each case assigned elastic compensating element , wherein a rib with an axially extending height is arranged in each case between two adjacent force action points , wherein the height of each rib varies from a force action point to an adjacent force action point , characterized in that the height of a rib decreases from a force action point to a circumferentially adjacent force action point , and in that the height of an adjacent rib increases again from the circumferentially adjacent force action point to the next force action point .
An electrical protection system , comprising connection terminals , separable electrical contacts connected between the connection terminals , a switching mechanism and at least one power switch connected in series with the separable electrical contacts, the separable electrical contacts being movable between an open state and a closed state, the switching mechanism comprising a movable operating lever and being coupled with the separable electrical contacts to switch the separable electrical contacts to the open state, the electrical protection system further comprising an electronic control circuit coupled to said at least one power switch , wherein the electrical protection system further comprises a sensor coupled to the operating lever to measure a position of the switching mechanism, and wherein the electronic control circuit is configured to switch said at least one power switch to a off state when the sensor detects that the switching mechanism has reached a position preceding a position from which the electrical contacts separate, characterised in that the relative movement of the parts of the switching mechanism is configured to cause the occurrence of an angular offset between the rotation of the control lever and the actual opening of the separable electrical contacts and in that the angular offset makes it possible to compensate for a reduction in the clearance, upon being pressed, of the separable electrical contacts caused by the gradual wear of the separable electrical contacts .
A method of continuous colour measurement of flat textiles on a measuring machine , in which the flat textile being measured is guided along a predetermined path, whereby the moving textile being measured is at the point of measurement illuminated by diffuse light, which is generated in an integrating sphere from reference light radiated by a source of light, whereby the diffuse light comes out of the integrating sphere through a measuring orifice , whose distance from the textile is maintained constant, and, simultaneously, having passed through the inner space of the integrating sphere the light being measured which contains diffuse light reflected and scattered off the textile is sensed from the inner surface of the integrator by one channel, whereas the reference light of the source of light is sensed from the inner space of the integrating sphere by the other channel, whereupon the instantaneous spectrum of the reference light is measured as well as the instantaneous spectrum of the measured light merged with the spectrum of the reference light, and from these values the spectrum of the colour of the textile being measured is computed, whereby the translucence of the textile , being measured is compensated for by placing a suitable screen under the textile being measured at the point of measuring, characterized in that the distance of the measuring orifice of the integrating sphere from the surface of the moving textile is continuously measured and maintained in the range of 1 ± 0,05 mm.