mhurhangee/patent-ind-claim-en huggingface dataset:
A pharmaceutical composition, comprising a pharmaceutically acceptable carrier and a compound of formula (I) or a salt thereof: wherein X is N or CH; each of R 1 , R 2 , R 3 , R 4 , and R 5 , independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, heteroaryl, halo, OR a , SR a , COOR a , OC(O)R a , C(O)R a , C(O)NR a R b , S(O) 2 NR a R b , or NR a R b ; each of R 6 , R 7 , R 8 , and R 9 , independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, heteroaryl, halo, OR a , SR a , COOR a , OC(O)R a , C(O)R a , C(O)NR a R b , S(O) 2 NR a R b , or NR a Rb; or R 6 and R 7 , R 7 and R 8 , or R 8 and R 9 , together with the carbon atoms to which they are attached, are aryl, heteroaryl, C 3 -C 20 cycloalkyl, or C 1 -C 20 heterocycloalkyl; R 10 is C 1 -C 10 alkyl; each R a , independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, or heteroaryl; and each R b , independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, or heteroaryl. X is N or CH; each of R 1 , R 2 , R 3 , R 4 , and R 5 , independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, heteroaryl, halo, OR a , SR a , COOR a , OC(O)R a , C(O)R a , C(O)NR a R b , S(O) 2 NR a R b , or NR a R b ; each of R 6 , R 7 , R 8 , and R 9 , independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, heteroaryl, halo, OR a , SR a , COOR a , OC(O)R a , C(O)R a , C(O)NR a R b , S(O) 2 NR a R b , or NR a Rb; or R 6 and R 7 , R 7 and R 8 , or R 8 and R 9 , together with the carbon atoms to which they are attached, are aryl, heteroaryl, C 3 -C 20 cycloalkyl, or C 1 -C 20 heterocycloalkyl; R 10 is C 1 -C 10 alkyl; each R a , independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, or heteroaryl; and each R b , independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, or heteroaryl.
Cooking apparatus comprising at least one housing device and at least one cooking cavity having at least one cooking cavity bottom , wherein at least one steam generating device is assigned to the cooking cavity for heating of food and is suitable and formed for supplying steam to the cooking cavity , and wherein at least one foil heating body is arranged on the outer side of the cooking cavity bottom , which is suitable and formed for heating the cooking cavity bottom at least in portions, such that the cooking cavity bottom has at least one shaped portion on which the foil heating body is provided, and that the foil heating body , at least in portions and substantially, engages positively the shaped portion , and the shaped portion has a predetermined maximum filling status for residual water , and at least one temperature sensor is assigned to the foil heating body , characterised in that temperature sensor and at least one safety device are assigned to the foil heating body , wherein the foil heating body is arranged on the shaped portion and/or that the temperature sensor and/or that the least one safety device is arranged on the foil heating body such that the temperature sensor and/or the at least one safety device is substantially assigned to a predetermined maximum filling status of the shaped portion and A) the temperature sensor and at least one safety device are opposite to one another and/or B) the temperature sensor and one of the at least one safety device are arranged on the outer portion of the foil heating body , and a further safety device is provided substantially in the centre on the foil heating body . A) the temperature sensor and at least one safety device are opposite to one another and/or B) the temperature sensor and one of the at least one safety device are arranged on the outer portion of the foil heating body , and a further safety device is provided substantially in the centre on the foil heating body .
A semiconductor module comprising a lead frame having a plurality of seats electrically independent of each other, a plurality of electronic parts including a plurality of semiconductor devices mounted on the seats , and a mold section provided by integrating the lead frame and the electronic parts with a mold resin, the plurality of electronic parts constituting a plurality of circuits, a portion of the lead frame extended to the outside of the mold section providing a plurality of terminals each connecting the circuit to an external part, comprising a common connecting section connecting at least one set of the terminals at the same potential in the circuits outside the mold section, and the common connecting section serves as a common wiring for power source lines, or ground lines, or other wirings in the circuits and serves as a terminal for the common wiring, wherein the common connecting section is formed of the lead frame extended to the outside of the mold section, characterized in that the common connecting section is bent in a direction orthogonal to a surface of the seat on which the semiconductor device is mounted, and that the common connecting section is bent opposite to a surface of the seat on which the semiconductor device is mounted.
A method for detecting a main vessel in a medical 3D volume represented by a digital voxel representation comprising the steps of - applying a segmentation algorithm to said volume resulting in a first binary mask with one of a first and a second class value assigned to each voxel of said volume, a first class value assigned to voxels of osseous tissue and a second class value assigned to vascular tissue, - applying a thresholding operation to said volume to obtain a second binary mask, - subtracting said second binary mask from said first binary mask to generate a third binary mask, - extracting connected components by propagating labels to all adjacent voxels indicative of a class to which they belong, - computing features for each connected component, said features indicating whether a component is considered part of an osseous or a vascular region, - preserving connected components on the basis of the results of said computed features and identifying the preserved component as said vessel. - applying a segmentation algorithm to said volume resulting in a first binary mask with one of a first and a second class value assigned to each voxel of said volume, a first class value assigned to voxels of osseous tissue and a second class value assigned to vascular tissue, - applying a thresholding operation to said volume to obtain a second binary mask, - subtracting said second binary mask from said first binary mask to generate a third binary mask, - extracting connected components by propagating labels to all adjacent voxels indicative of a class to which they belong, - computing features for each connected component, said features indicating whether a component is considered part of an osseous or a vascular region, - preserving connected components on the basis of the results of said computed features and identifying the preserved component as said vessel.
A method for obtaining an animal model for screening anti-tumor drugs, comprising cultivating a primary tumor cell obtained from a tumor sample of a patient in a composition comprising: a) 0.4 mg/L Hydrocortisone; b) 5 mg/L Insulin; c) 8.3 μg/L Cholera toxin; d) 24.2 mg/L Adenine; e) 10 μg/L EGF; f) 10 μmol/L Y- 27632; g) Pen/Strep; h) 10% FBS; i) F12 medium j) DMEM with high glucose k) Non-Essential Amino Acids Solution; l) GlutaMAX Supplement; and m) a mouse embryonic fibroblast cell that has been treated with mitomycin C; and implanting the primary tumor cell obtained from step into an animal, wherein the animal is a mouse. cultivating a primary tumor cell obtained from a tumor sample of a patient in a composition comprising: a) 0.4 mg/L Hydrocortisone; b) 5 mg/L Insulin; c) 8.3 μg/L Cholera toxin; d) 24.2 mg/L Adenine; e) 10 μg/L EGF; f) 10 μmol/L Y- 27632; g) Pen/Strep; h) 10% FBS; i) F12 medium j) DMEM with high glucose k) Non-Essential Amino Acids Solution; l) GlutaMAX Supplement; and m) a mouse embryonic fibroblast cell that has been treated with mitomycin C; and a) 0.4 mg/L Hydrocortisone; b) 5 mg/L Insulin; c) 8.3 μg/L Cholera toxin; d) 24.2 mg/L Adenine; e) 10 μg/L EGF; f) 10 μmol/L Y- 27632; g) Pen/Strep; h) 10% FBS; i) F12 medium j) DMEM with high glucose k) Non-Essential Amino Acids Solution; l) GlutaMAX Supplement; and m) a mouse embryonic fibroblast cell that has been treated with mitomycin C; and implanting the primary tumor cell obtained from step into an animal, wherein the animal is a mouse.
A sample isolation kit (1; 101) comprising: a separation unit configured to separate an isolation object sample from a biological sample; an isolation unit having a sample fluid channel and an isolation channel , wherein the isolation unit is configured to isolate a target biological sample from the isolation object sample; a housing configured to detachably couple to the sample fluid channel of the isolation unit and provide the isolation object sample to the isolation unit; and a storage housing configured to detachably couple to the isolation channel of the isolation unit and receive the target biological sample isolated from the isolation object sample by the isolation unit; wherein the housing and the isolation unit are coupled using a hermetic seal ; and wherein the storage housing and the isolation unit are coupled using a further hermetic seal . a separation unit configured to separate an isolation object sample from a biological sample; an isolation unit having a sample fluid channel and an isolation channel , wherein the isolation unit is configured to isolate a target biological sample from the isolation object sample; a housing configured to detachably couple to the sample fluid channel of the isolation unit and provide the isolation object sample to the isolation unit; and a storage housing configured to detachably couple to the isolation channel of the isolation unit and receive the target biological sample isolated from the isolation object sample by the isolation unit; wherein the housing and the isolation unit are coupled using a hermetic seal ; and wherein the storage housing and the isolation unit are coupled using a further hermetic seal .
A multi-functional workbench comprising: - a worktop provided with a girder , the girder having a bottom provided with a receiving space; - a plurality of supporting legs which are foldable and can be stored into the receiving space; - a first locking mechanism configured to lock the supporting legs when the supporting legs are unfolded; and - a third locking mechanism disposed on the girder for securing the supporting legs when the supporting legs are folded inside the receiving space ; characterized in that four concave-shaped mechanisms are fixed in the receiving space and are connected by two square tubes each of which has two ends which are rotatable; the supporting legs are connected to the square tubes , drive the rotation of the square tubes and are rotatably engageable into the concave shaped mechanisms to be received in the receiving space; the first locking mechanism is disposed between two supporting legs that are connected to the same square tube ; wherein each concave-shaped mechanism has a recess , the recesses of the two concave-shaped mechanisms connected to the same square tube are disposed oppositely, the supporting legs are attached to the square tube in between the recesses , and protrusions of the recesses restrict the continuous rotation of the supporting legs when the supporting legs are engaged into the recesses . - a worktop provided with a girder , the girder having a bottom provided with a receiving space; - a plurality of supporting legs which are foldable and can be stored into the receiving space; - a first locking mechanism configured to lock the supporting legs when the supporting legs are unfolded; and - a third locking mechanism disposed on the girder for securing the supporting legs when the supporting legs are folded inside the receiving space ;
A method of generating batches of food items, comprising: • transferring food items to a weight determination means where the weight of the food items are obtained for single food items and/or food items in groups, • generating a plurality of batches based on the obtained weight of the single food items and/or food items in groups, wherein the step of generating batches is controlled such that the weight of batches is within a pre-defined weight range, characterised in that the distribution of the batches within the weight range is pre-defined. • transferring food items to a weight determination means where the weight of the food items are obtained for single food items and/or food items in groups, • generating a plurality of batches based on the obtained weight of the single food items and/or food items in groups, wherein the step of generating batches is controlled such that the weight of batches is within a pre-defined weight range, characterised in that the distribution of the batches within the weight range is pre-defined.
Model suitable to guide a user for obtaining a rush, the rush being a recorded frame resulting from the recording of a frame to be recorded which is filmed or photographed by the user, the rush being intended to complete a framework of a film or a series of images or an image in which at least one space corresponding to the rush has been left vacant, in order to form a personalized film or a personalized series of images or a personalized image, the model being characterized in that it comprises at least one frame provided with an assistance template comprising at least one template element of the frame to be recorded ensuring that the recorded frame can be reintegrated into the framework, the assistance template comprising at least one assistance tracing indicating what should be the position of an object or a person in the framing and at least one element which represents a characteristic of the frame chosen from: a duration, a focal length, a movement, a light, a contrast, a framing format, a box orientation format and an image format.
An article coated on at least one surface with a coating composition, wherein the coating composition comprises: (a) a polyester polymer derived by esterifying an aryloxy ether polyol derived from reaction between: (i) a polyhydric phenol or a polyphenol and a non-hydroxyl functional cyclic carbonate, or (ii) a monophenol and a hydroxyl functional cyclic carbonate; (b) a crosslinker and (c) an optional catalyst, wherein the surface comprises a food-contact surface and wherein the article comprises a food or beverage can. (a) a polyester polymer derived by esterifying an aryloxy ether polyol derived from reaction between: (i) a polyhydric phenol or a polyphenol and a non-hydroxyl functional cyclic carbonate, or (ii) a monophenol and a hydroxyl functional cyclic carbonate; (i) a polyhydric phenol or a polyphenol and a non-hydroxyl functional cyclic carbonate, or (ii) a monophenol and a hydroxyl functional cyclic carbonate; (b) a crosslinker and (c) an optional catalyst,
A manufacturing method for laminated curved glass, wherein the laminated curved glass comprises a first glass plate, a second glass plate, and an adhesive film configured between the first glass plate and the second glass plate, the thickness of the first glass plate and the second glass plate is 0.1 mm to 2.2 mm, and the manufacturing method of the laminated curved glass comprised the following steps: providing the flat first glass plate and the flat second glass plate with a thickness of 0.1 mm to 2.2 mm; impose the first glass plate and the second glass plate with strengthening treatment, the processed first glass plate and the processed second glass plate are in the shape of a flat plate, and the surface stress of the first glass plate or the second glass plate is 10-1000MPa, the surface stress is tested by a surface stress meter, as further specified in the description; and low temperature molding process: providing the adhesive film, and laminating the first glass plate processed in step . the adhesive film, and the second glass plate processed in step in sequence, and then performing the low temperature press molding process to obtain the laminated curved glass: the low temperature molding process is performed in a cold pressing device, the cold pressing device comprises a first mold for molding the first glass plate into a curved shape and a second mold for molding the second glass plate into a curved shape, the heating temperature of the first mold or the second mold is 80 °C to 380 °C, the first glass plate is pressed by the first mold so that the first glass plate is attached to the concave surface of the first mold, and the second glass plate is pressed by the second mold so that the second glass plate is attached to the convex surface of the second mold. providing the flat first glass plate and the flat second glass plate with a thickness of 0.1 mm to 2.2 mm; impose the first glass plate and the second glass plate with strengthening treatment, the processed first glass plate and the processed second glass plate are in the shape of a flat plate, and the surface stress of the first glass plate or the second glass plate is 10-1000MPa, the surface stress is tested by a surface stress meter, as further specified in the description; and low temperature molding process: providing the adhesive film, and laminating the first glass plate processed in step . the adhesive film, and the second glass plate processed in step in sequence, and then performing the low temperature press molding process to obtain the laminated curved glass: the low temperature molding process is performed in a cold pressing device, the cold pressing device comprises a first mold for molding the first glass plate into a curved shape and a second mold for molding the second glass plate into a curved shape, the heating temperature of the first mold or the second mold is 80 °C to 380 °C, the first glass plate is pressed by the first mold so that the first glass plate is attached to the concave surface of the first mold, and the second glass plate is pressed by the second mold so that the second glass plate is attached to the convex surface of the second mold.
A transdermal drug delivery device (10;110) comprising: a housing (12;112) including an upper housing portion (14;114) and a lower housing portion (16;116), the lower housing portion (16;116) defining a bottom surface (20;120) including skin attachment means for releaseably attaching the lower housing portion (16;116) to skin of a user, the upper housing portion (14;114) at least partially surrounding a central region (30;130) of the device (10;110); a microneedle assembly (36;136) disposed within the central region (30;130); a reservoir (38;138) disposed within the central region (30;130) , the reservoir (38;138) being in fluid communication with the microneedle assembly (36;136); and a pushing element (40;140) disposed above the microneedle assembly (36;136) within the central region (30;130); characterised by the pushing element (40;140) being configured to provide a continuous bilateral force having a downward component transmitted through the microneedle assembly (36;136) and an upward component transmitted through the skin attachment means; wherein the microneedle assembly (36;136) is configured to move independently of the lower housing portion (16;116). a housing (12;112) including an upper housing portion (14;114) and a lower housing portion (16;116), the lower housing portion (16;116) defining a bottom surface (20;120) including skin attachment means for releaseably attaching the lower housing portion (16;116) to skin of a user, the upper housing portion (14;114) at least partially surrounding a central region (30;130) of the device (10;110); a microneedle assembly (36;136) disposed within the central region (30;130); a reservoir (38;138) disposed within the central region (30;130) , the reservoir (38;138) being in fluid communication with the microneedle assembly (36;136); and a pushing element (40;140) disposed above the microneedle assembly (36;136) within the central region (30;130); characterised by the pushing element (40;140) being configured to provide a continuous bilateral force having a downward component transmitted through the microneedle assembly (36;136) and an upward component transmitted through the skin attachment means; wherein the microneedle assembly (36;136) is configured to move independently of the lower housing portion (16;116).