mhurhangee/patent-ind-claim-en huggingface dataset:
A computer-implemented method of identifying mutations due to an advanced stage of disease in a subject, comprising: obtaining sequence data comprising a first nucleic acid sequence corresponding to a non-diseased sample from the subject and a second nucleic acid sequence corresponding to a diseased sample from the subject; identifying differences between the first sequence and the second sequence; preparing a reference sequence construct representing the differences between the first sequence and the second sequence as two or more alternative paths in a reference directed acyclic graph (DAG) comprising nodes, each node representing one or more characters in the reference sequence construct, wherein the alternative paths are placed at positions in the reference sequence construct where there is a difference between the first sequence and the second sequence; aligning a nucleic acid sequence read from a sequence corresponding to an advanced disease sample from said subject to the reference sequence construct; and identifying, based on the aligned nucleic acid sequence read to the reference sequence construct, differences between the sequence read and the reference sequence construct as mutations due to an advanced stage of the disease, wherein the disease is cancer. obtaining sequence data comprising a first nucleic acid sequence corresponding to a non-diseased sample from the subject and a second nucleic acid sequence corresponding to a diseased sample from the subject; identifying differences between the first sequence and the second sequence; preparing a reference sequence construct representing the differences between the first sequence and the second sequence as two or more alternative paths in a reference directed acyclic graph (DAG) comprising nodes, each node representing one or more characters in the reference sequence construct, wherein the alternative paths are placed at positions in the reference sequence construct where there is a difference between the first sequence and the second sequence; aligning a nucleic acid sequence read from a sequence corresponding to an advanced disease sample from said subject to the reference sequence construct; and identifying, based on the aligned nucleic acid sequence read to the reference sequence construct, differences between the sequence read and the reference sequence construct as mutations due to an advanced stage of the disease, wherein the disease is cancer.
A method of determining the risk of recurrence of endometrial cancer in a subject diagnosed with stage I/II endometrial cancer comprising: a) testing a sample of the subject for a mutation in the ESR1 gene; and b) indicating the subject is not at risk of recurrence if the ESR1 gene is not mutated or the subject is at risk of recurrence if the ESR1 gene is mutated, and wherein the stage I/II endometrial cancer comprises low copy number (CN-low) changes and microsatellite instability (MSI). a) testing a sample of the subject for a mutation in the ESR1 gene; and b) indicating the subject is not at risk of recurrence if the ESR1 gene is not mutated or the subject is at risk of recurrence if the ESR1 gene is mutated, and wherein the stage I/II endometrial cancer comprises low copy number (CN-low) changes and microsatellite instability (MSI).
A computer-implemented method executed by one or more processors, the method comprising: receiving an electronic communication between a customer and an agent, the electronic communication comprising an agent media stream associated with speech from the agent and a customer media stream associated with speech from the customer; characterised in that the method further comprises: sending a forked media stream for analysis during the electronic communication between the customer and the agent, the forked media stream being a separate media stream that replicates only the agent media stream from the electronic communication; receiving , from analysis of the forked media stream, analysis results that indicate a topic being discussed between the customer and the agent during the electronic communication, wherein the analysis results comprise a token that indicates the topic being discussed between the customer and the agent; determining whether to send a notification for display on a computing device assigned to the agent, comprising identifying, from among a plurality of different rules, a training rule that is specific to the agent and associated with the token and the notification includes one or more training reminders relevant to the topic being discussed between the customer and the agent. receiving an electronic communication between a customer and an agent, the electronic communication comprising an agent media stream associated with speech from the agent and a customer media stream associated with speech from the customer; characterised in that the method further comprises: sending a forked media stream for analysis during the electronic communication between the customer and the agent, the forked media stream being a separate media stream that replicates only the agent media stream from the electronic communication; receiving , from analysis of the forked media stream, analysis results that indicate a topic being discussed between the customer and the agent during the electronic communication, wherein the analysis results comprise a token that indicates the topic being discussed between the customer and the agent; determining whether to send a notification for display on a computing device assigned to the agent, comprising identifying, from among a plurality of different rules, a training rule that is specific to the agent and associated with the token and the notification includes one or more training reminders relevant to the topic being discussed between the customer and the agent.
A method for determining and/or monitoring the state of an extracorporeal fluid or an extracorporeal fluid flow, wherein the fluid is monitored by means of ultrasound, characterised in that the fluid is blood which is present in an extracorporeal circuit of an extracorporeal blood treatment machine and the extracorporeal fluid or the extracorporeal fluid flow is excited time-harmonically mechanically and/or transiently mechanically and the Doppler frequency shift and the viscosity are determined instantaneously and simultaneously by the ultrasound backscatter signal, the characteristics of the state of the extracoporal fluid determined by means of the ultrasonic monitoring are processed with a multi-criteria ultrasonic analysis, in particular an evaluation algorithm, whereby a change in the distribution of particles contained in the fluid and changes in the viscosity of the fluid are measured by means of ultrasound and the fluid state is assigned to previously defined states.
A surgical system for projecting illumination onto an eye, one or more cannulas being inserted into the eye, comprising: a microscope ; a camera communicatively coupled to a surgical console, the camera operable to collect image data of an eye ; and the surgical console communicatively coupled to the camera , the surgical console operable to receive the image data, the surgical console comprising: a processor ; and a memory , the memory comprising code executable by the processor; wherein the processor is configured: to process the image data in a manner defined by the code to identify said one or more cannulas inserted into the eye ; and to determine one or more discrete zones of the eye surface to be illuminated, wherein the one or more discrete zones encompass the one or more cannulas to the exclusion of the remainder of the eye surface based on the received image data; a projector communicatively coupled to the surgical console , and configured to receive the desired light projection and to project visible, non-treatment light onto the eye surface ; wherein the projected light is in the form of one or more discrete light projections is directed to the one or more discrete zones of the eye surface to selectively illuminate each of the one or more cannulas to form a lighted zone at each of the one or more cannulas conforming to a shape of said cannula. a microscope ; a camera communicatively coupled to a surgical console, the camera operable to collect image data of an eye ; and the surgical console communicatively coupled to the camera , the surgical console operable to receive the image data, the surgical console comprising: a processor ; and a memory , the memory comprising code executable by the processor; a processor ; and a memory , the memory comprising code executable by the processor; wherein the processor is configured: to process the image data in a manner defined by the code to identify said one or more cannulas inserted into the eye ; and to determine one or more discrete zones of the eye surface to be illuminated, wherein the one or more discrete zones encompass the one or more cannulas to the exclusion of the remainder of the eye surface based on the received image data; to process the image data in a manner defined by the code to identify said one or more cannulas inserted into the eye ; and to determine one or more discrete zones of the eye surface to be illuminated, wherein the one or more discrete zones encompass the one or more cannulas to the exclusion of the remainder of the eye surface based on the received image data; a projector communicatively coupled to the surgical console , and configured to receive the desired light projection and to project visible, non-treatment light onto the eye surface ; wherein the projected light is in the form of one or more discrete light projections is directed to the one or more discrete zones of the eye surface to selectively illuminate each of the one or more cannulas to form a lighted zone at each of the one or more cannulas conforming to a shape of said cannula.
A process for oxidizing one or more thiol compounds from an alkaline stream , and separating the oil by-product and excess air from the oxidized alkaline stream in a single vessel, comprising: A) passing a mixed stream comprising the alkaline stream and air to a vessel having an oxidation section , a dividing wall , a separation section , and an elongated neck comprising a vent gas section, wherein all sections comprise one or more packing elements , the latter two sections also contain a scrubbing feature which entails a distributor , and a mesh ; B) passing an oxidized alkaline stream over the dividing wall to the separation section containing a first chamber and a second chamber wherein the first chamber contains a coated mesh ; and C) passing a vent gas stream, also known as spent air, via the neck where the vent gas is scrubbed by wash oil then to a vent tank, wherein the spent air passes through mesh , and then through an extended disengaging space , which functions as the vent tank. A) passing a mixed stream comprising the alkaline stream and air to a vessel having an oxidation section , a dividing wall , a separation section , and an elongated neck comprising a vent gas section, wherein all sections comprise one or more packing elements , the latter two sections also contain a scrubbing feature which entails a distributor , and a mesh ; B) passing an oxidized alkaline stream over the dividing wall to the separation section containing a first chamber and a second chamber wherein the first chamber contains a coated mesh ; and C) passing a vent gas stream, also known as spent air, via the neck where the vent gas is scrubbed by wash oil then to a vent tank, wherein the spent air passes through mesh , and then through an extended disengaging space , which functions as the vent tank.
An image forming apparatus comprising: a first generation unit configured to generate a graphic object from a drawing command set for printing the graphic object included in a print job; a second generation unit configured to generate a first mask image by rendering the graphic object; a third generation unit configured to generate a second mask image by shifting the first mask image in a thickening direction by the number of pixels of a thickening width; a fourth generation unit configured to generate a third mask image by logically composing the first mask image and the second mask image; a fifth generation unit configured to convert the third mask image into intermediate data; and a sixth generation unit configured to generate a raster image by rendering of the intermediate data, characterized in that the second generation unit generates the first mask image by rendering graphic objects that satisfy specific conditions among a plurality of graphic objects generated by the first generation unit in a case where the print job includes a drawing command set for printing a plurality of graphic objects, and in that the graphic objects that satisfy the specific conditions are a plurality of graphic objects of which drawing areas do not overlap and of which fills are identical. a first generation unit configured to generate a graphic object from a drawing command set for printing the graphic object included in a print job; a second generation unit configured to generate a first mask image by rendering the graphic object; a third generation unit configured to generate a second mask image by shifting the first mask image in a thickening direction by the number of pixels of a thickening width; a fourth generation unit configured to generate a third mask image by logically composing the first mask image and the second mask image; a fifth generation unit configured to convert the third mask image into intermediate data; and a sixth generation unit configured to generate a raster image by rendering of the intermediate data, characterized in that the second generation unit generates the first mask image by rendering graphic objects that satisfy specific conditions among a plurality of graphic objects generated by the first generation unit in a case where the print job includes a drawing command set for printing a plurality of graphic objects, and in that the graphic objects that satisfy the specific conditions are a plurality of graphic objects of which drawing areas do not overlap and of which fills are identical.
A dual sensor module , comprising: a substrate ; a light source disposed on the substrate ; a photodetector disposed on the substrate ; two electrodes both disposed on and electrically connected to the substrate and obtaining an electrical potential difference, characterized in that : it further comprises a first encapsulant formed over the light source and a second encapsulant formed over the photodetector ; and in that one of the two electrodes is disposed on a border of the substrate and laterally to the light source . a substrate ; a light source disposed on the substrate ; a photodetector disposed on the substrate ; two electrodes both disposed on and electrically connected to the substrate and obtaining an electrical potential difference, characterized in that : it further comprises a first encapsulant formed over the light source and a second encapsulant formed over the photodetector ; and in that one of the two electrodes is disposed on a border of the substrate and laterally to the light source .
A method for controlling streaming of media content to a media device, the method comprising: receiving a first user input at a wireless communications device to generate a first media control message for controlling delivery of the media content to the media device which is remote from the wireless communications device; transmitting the first media control message from the wireless communications device over a network; receiving the first media control message over the network at a clearinghouse ; at the clearinghouse, determining a media provider distribution facility to send the media control message to, based on the first media control message received from the wireless communications device ; converting the first media control message at the clearinghouse into a command format that is required by the determined media provider distribution facility ; transmitting the converted first media control message to the determined media provider distribution facility , wherein the converted first media control message contains information for use by the determined media provider distribution facility to initiate streaming of the media content from the media provider distribution facility to the media device ; receiving the media content at the media device; and receiving a second user input at the wireless communications device to generate a second media control message for controlling playback of the media content at the media device. receiving a first user input at a wireless communications device to generate a first media control message for controlling delivery of the media content to the media device which is remote from the wireless communications device; transmitting the first media control message from the wireless communications device over a network; receiving the first media control message over the network at a clearinghouse ; at the clearinghouse, determining a media provider distribution facility to send the media control message to, based on the first media control message received from the wireless communications device ; converting the first media control message at the clearinghouse into a command format that is required by the determined media provider distribution facility ; transmitting the converted first media control message to the determined media provider distribution facility , wherein the converted first media control message contains information for use by the determined media provider distribution facility to initiate streaming of the media content from the media provider distribution facility to the media device ; receiving the media content at the media device; and receiving a second user input at the wireless communications device to generate a second media control message for controlling playback of the media content at the media device.
A cell processing system comprising: at least one processor connectable to a source container filled with a biological fluid, the processor comprising: a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet; one or more containers selectively connected to the first outlet; and a magnet ; a controller coupled to the at least one processor and configured: to operate the spinning membrane to receive biological fluid from the source container and to direct the target cells to one of the one or more containers , to pause to permit magnetic particles to be associated with the target cells, to operate the spinning membrane to receive the contents of the one of the one or more containers with the magnet applied to the target cells associated with the magnetic particles; to deactivate the magnet applied to the target cells associated with the magnetic particles in the one of the one of more containers; to prompt an operator to remove in a sterile manner the one of the one or more containers. at least one processor connectable to a source container filled with a biological fluid, the processor comprising: a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet; one or more containers selectively connected to the first outlet; and a magnet ; a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet; one or more containers selectively connected to the first outlet; and a magnet ; a controller coupled to the at least one processor and configured: to operate the spinning membrane to receive biological fluid from the source container and to direct the target cells to one of the one or more containers , to pause to permit magnetic particles to be associated with the target cells, to operate the spinning membrane to receive the contents of the one of the one or more containers with the magnet applied to the target cells associated with the magnetic particles; to deactivate the magnet applied to the target cells associated with the magnetic particles in the one of the one of more containers; to prompt an operator to remove in a sterile manner the one of the one or more containers. to operate the spinning membrane to receive biological fluid from the source container and to direct the target cells to one of the one or more containers , to pause to permit magnetic particles to be associated with the target cells, to operate the spinning membrane to receive the contents of the one of the one or more containers with the magnet applied to the target cells associated with the magnetic particles; to deactivate the magnet applied to the target cells associated with the magnetic particles in the one of the one of more containers; to prompt an operator to remove in a sterile manner the one of the one or more containers.
A MEMS ohmic switch , comprising: a substrate having one or more anchor electrodes , a plurality of pull-down electrodes (104A-104C) and one or more RF electrodes disposed thereon; a MEMS bridge coupled to the one or more anchor electrodes with an anchor contact layer ; a dielectric layer disposed over the plurality of pull-down electrodes (104A-104C); a center stopper coupled to the dielectric layer and disposed under a substantially center of the MEMS bridge, characterised in that it further comprises: a first RF contact and a second RF contact are both coupled to a respective RF electrode of the one or more RF electrodes ; and an additional stopper disposed on the dielectric layer , wherein the additional stopper is disposed between the anchor contact layer and the first RF contact and wherein the first RF contact is disposed between the additional stopper and the center stopper , and the first RF contact and the second RF contact are disposed on the one or more RF electrodes . a substrate having one or more anchor electrodes , a plurality of pull-down electrodes (104A-104C) and one or more RF electrodes disposed thereon; a MEMS bridge coupled to the one or more anchor electrodes with an anchor contact layer ; a dielectric layer disposed over the plurality of pull-down electrodes (104A-104C); a center stopper coupled to the dielectric layer and disposed under a substantially center of the MEMS bridge, characterised in that it further comprises: a first RF contact and a second RF contact are both coupled to a respective RF electrode of the one or more RF electrodes ; and an additional stopper disposed on the dielectric layer , wherein the additional stopper is disposed between the anchor contact layer and the first RF contact and wherein the first RF contact is disposed between the additional stopper and the center stopper , and the first RF contact and the second RF contact are disposed on the one or more RF electrodes . a first RF contact and a second RF contact are both coupled to a respective RF electrode of the one or more RF electrodes ; and an additional stopper disposed on the dielectric layer , wherein the additional stopper is disposed between the anchor contact layer and the first RF contact and wherein the first RF contact is disposed between the additional stopper and the center stopper , and the first RF contact and the second RF contact are disposed on the one or more RF electrodes .