mhurhangee/patent-ind-claim-en huggingface dataset:
An apparatus , capable of altering the heart rate, configured to provide a relaxing or stimulating effect on the user, the apparatus comprising: a wearable device configured to engage the user's skin and to provide a rhythmic tactile stimulus to the user capable of altering the user's heart rate; an arrangement for securing the device to the user such that the device can apply the stimulus to the user; and one or more control means for adjusting the frequency, tempo, duration and/or intensity of the stimulus so as to provide a rhythmic tactile stimulus at a rate that is faster or slower than the user's actual heart rate to provide the relaxing or stimulating effect. wherein the device is configured to provide the stimulus in the form of a beat that substantially matches the form of a user's heartbeat. a wearable device configured to engage the user's skin and to provide a rhythmic tactile stimulus to the user capable of altering the user's heart rate; an arrangement for securing the device to the user such that the device can apply the stimulus to the user; and one or more control means for adjusting the frequency, tempo, duration and/or intensity of the stimulus so as to provide a rhythmic tactile stimulus at a rate that is faster or slower than the user's actual heart rate to provide the relaxing or stimulating effect. wherein the device is configured to provide the stimulus in the form of a beat that substantially matches the form of a user's heartbeat.
An immunosuppressive trans-activator of transcription (Tat) derivative polypeptide, the Tat derivative polypeptide comprising an amino acid sequence comprising the following domains in the indicated order: a transcription factor (TF) domain, a cysteine-rich domain, and a C-terminal domain, wherein the amino acid sequence comprises SEQ ID NO: 9.
Apparatus for processing a received radio signal, the apparatus comprising means (5, 6, P; 41, 42) configured for: - processing (S1) received radio signal data with a first signal processing chain , wherein said first processing chain comprises at least one first processing module configured for determining first output data (y 1 , z 1 ) based on said received radio signal data, - processing (S1) said received radio signal data with a second signal processing chain , wherein said second processing chain comprises at least one second processing module configured for determining an estimation (y 2 , z 2 ) of said first output data (y 1 , z 1 ) based on said received radio signal data, and at least one neural network configured for determining second output data (y 3 , z 3 ) based on said estimation (y 2 , z 2 ), - updating (S2) parameters of said at least one neural network based on a comparison between said first output data (y 1 , z 1 ) and said second output data (y 3 , z 3 ), - after said updating (S2), processing (S4) said received radio signal data with said second signal processing chain , without applying said at least one first processing module . - processing (S1) received radio signal data with a first signal processing chain , wherein said first processing chain comprises at least one first processing module configured for determining first output data (y 1 , z 1 ) based on said received radio signal data, - processing (S1) said received radio signal data with a second signal processing chain , wherein said second processing chain comprises at least one second processing module configured for determining an estimation (y 2 , z 2 ) of said first output data (y 1 , z 1 ) based on said received radio signal data, and at least one neural network configured for determining second output data (y 3 , z 3 ) based on said estimation (y 2 , z 2 ), - updating (S2) parameters of said at least one neural network based on a comparison between said first output data (y 1 , z 1 ) and said second output data (y 3 , z 3 ), - after said updating (S2), processing (S4) said received radio signal data with said second signal processing chain , without applying said at least one first processing module .
An antibody that binds human growth-regulated oncogene ("Gro")-alpha, human Gro-beta, human Gro-gamma, human epithelial neutrophil activating peptide-78, human granulocyte chemotactic protein-2, human neutrophil activating protein-2, and human interleukin-8, wherein the antibody comprises light chain complementarity determining regions ("LCDR") LCDR1, LCDR2, LCDR3 and heavy chain complementarity determining regions ("HCDR") HCDR1, HCDR2, HCDR3, wherein LCDR1 comprises SEQ ID NO: 7, LCDR2 comprises SEQ ID NO: 8, LCDR3 comprises SEQ ID NO: 9, HCDR1 comprises SEQ ID NO: 10, HCDR2 comprises SEQ ID NO: 11, and HCDR3 comprises SEQ ID NO: 12, for use in the treatment of hidradenitis suppurativa.
A method comprising: determining, by an ingress router of a label switched path, LSP, , an error in a forwarding state for the LSP; in response to determining the error in the forwarding state for the LSP, generating, by the ingress router, an end-to-end path message including at least a flag for instructing a transit router along the LSP to reprogram label information of its forwarding engine with label information stored by a routing engine of the transit router for the LSP, the forwarding engine configured to provide data plane functionality for the transit router, the routing engine configured to provide control plane functionality for the transit router; sending, by the ingress router, the end-to-end path message including at least the flag to the transit router; and reprogramming, by the transit router and based on the flag, the label information stored by the forwarding engine of the transit router for the LSP with the label information stored by the routing engine of the transit router for the LSP. determining, by an ingress router of a label switched path, LSP, , an error in a forwarding state for the LSP; in response to determining the error in the forwarding state for the LSP, generating, by the ingress router, an end-to-end path message including at least a flag for instructing a transit router along the LSP to reprogram label information of its forwarding engine with label information stored by a routing engine of the transit router for the LSP, the forwarding engine configured to provide data plane functionality for the transit router, the routing engine configured to provide control plane functionality for the transit router; sending, by the ingress router, the end-to-end path message including at least the flag to the transit router; and reprogramming, by the transit router and based on the flag, the label information stored by the forwarding engine of the transit router for the LSP with the label information stored by the routing engine of the transit router for the LSP.
A method for determining a precoding matrix indicator, comprising: sending a first reference signal set to user equipment, wherein the first reference signal set is associated with a user equipment-specific matrix set, and each matrix in the user equipment-specific matrix set comprises at least one column, and each column comprises at least two rows; receiving a precoding matrix indicator PMI sent by the user equipment, wherein the PMI is used for indicating a precoding matrix that is selected based on the first reference signal set by the user equipment, the precoding matrix W is a product of two matrices W 1 and W 2 , W=W 1 W 2 , the matrix W 1 is a block diagonal matrix comprising two same block matrices X, each block matrix X is a kronecker product of two matrices C and D, X=CXD, and at least one matrix in the two matrices C and D is a function of the user equipment-specific matrix set, each matrix of the matrix W 2 , the matrix C and the matrix D comprises at least one column, and each column comprises at least two rows, and the PMI comprises three indexes i 6 , i 7 and is, wherein the index i 6 indicates the matrix C, the index i 7 indicates the matrix D, and the index i 8 indicates the matrix W 2 . sending a first reference signal set to user equipment, wherein the first reference signal set is associated with a user equipment-specific matrix set, and each matrix in the user equipment-specific matrix set comprises at least one column, and each column comprises at least two rows; receiving a precoding matrix indicator PMI sent by the user equipment, wherein the PMI is used for indicating a precoding matrix that is selected based on the first reference signal set by the user equipment, the precoding matrix W is a product of two matrices W 1 and W 2 , W=W 1 W 2 , the matrix W 1 is a block diagonal matrix comprising two same block matrices X, each block matrix X is a kronecker product of two matrices C and D, X=CXD, and at least one matrix in the two matrices C and D is a function of the user equipment-specific matrix set, each matrix of the matrix W 2 , the matrix C and the matrix D comprises at least one column, and each column comprises at least two rows, and the PMI comprises three indexes i 6 , i 7 and is, wherein the index i 6 indicates the matrix C, the index i 7 indicates the matrix D, and the index i 8 indicates the matrix W 2 .
A lubricant composition, characterized in that the lubricant composition comprises a base oil and rubber particles having radiation crosslinked structure dispersed therein, wherein the base oil is the continuous phase and the rubber particles are the dispersed phase, wherein the rubber particles are at least one selected from the group consisting of natural rubber, styrene-butadiene rubber, carboxylated styrene-butadiene rubber, nitrile rubber, carboxylated nitrile rubber, polybutadiene rubber, silicone rubber, chloroprene rubber, acrylate rubber, styrene-butadiene pyridine rubber, isoprene rubber, butyl rubber, polysulfide rubber, acrylate-butadiene rubber, polyurethane rubber, fluoro rubber and ethylene-vinyl acetate rubber, wherein the rubber particles have an average particle size of 20-2000 nm, a gel content of 60 wt% or more and are of a homogeneous structure, measured as indicated in the description, wherein the amount of the rubber particles is 0.001 to 200 parts by weight, in relation to 100 parts by weight of the base oil. wherein the rubber particles are at least one selected from the group consisting of natural rubber, styrene-butadiene rubber, carboxylated styrene-butadiene rubber, nitrile rubber, carboxylated nitrile rubber, polybutadiene rubber, silicone rubber, chloroprene rubber, acrylate rubber, styrene-butadiene pyridine rubber, isoprene rubber, butyl rubber, polysulfide rubber, acrylate-butadiene rubber, polyurethane rubber, fluoro rubber and ethylene-vinyl acetate rubber, wherein the rubber particles have an average particle size of 20-2000 nm, a gel content of 60 wt% or more and are of a homogeneous structure, measured as indicated in the description, wherein the amount of the rubber particles is 0.001 to 200 parts by weight, in relation to 100 parts by weight of the base oil.
A suction diffuser or arrangement comprising: a main suction diffuser body configured with an inlet to receive an incoming fluid (F i ), an interior cavity to receive the incoming fluid (F i ) from the inlet , and an outlet to receive the incoming fluid (F i ) from the interior cavity and provide an outgoing fluid (F o ), and a flow conditioning arrangement configured in relation to the inlet and comprising a flow conditioning portion having at least one inwardly contoured surface , configured to extend into the interior cavity , diffuse the incoming fluid (F i ) passing from the inlet into the interior cavity , and provide a flow conditioning that produces a uniform flow of the outgoing fluid (F o ) by directing the incoming fluid (F i ) towards the outlet , based at least partly on a contoured design corresponding to the at least one inwardly contoured surface , characterized in that the flow conditioning arrangement comprises a baffle configured in the interior cavity to restrain or regulate the flow of the fluid from the inlet to the outlet , wherein the baffle includes an end portion configured with a shape that substantially corresponds to the shape of the at least one inwardly contoured surface so as to mate or fit together with the same, and wherein the flow conditioning portion also has at least one slot (14c 1 , 14c 2 , 14c 3 , 14c 4 ; 148a 148b, 148c, 148d) configured to receive and engage the end portion of the baffle , wherein the at least one slot (14c 1 , 14c 2 , 14c 3 , 14c 4 ; 148a 148b, 148c, 148d) is formed in the at least one inwardly contoured surface . a main suction diffuser body configured with an inlet to receive an incoming fluid (F i ), an interior cavity to receive the incoming fluid (F i ) from the inlet , and an outlet to receive the incoming fluid (F i ) from the interior cavity and provide an outgoing fluid (F o ), and a flow conditioning arrangement configured in relation to the inlet and comprising a flow conditioning portion having at least one inwardly contoured surface , configured to extend into the interior cavity , diffuse the incoming fluid (F i ) passing from the inlet into the interior cavity , and provide a flow conditioning that produces a uniform flow of the outgoing fluid (F o ) by directing the incoming fluid (F i ) towards the outlet , based at least partly on a contoured design corresponding to the at least one inwardly contoured surface , characterized in that the flow conditioning arrangement comprises a baffle configured in the interior cavity to restrain or regulate the flow of the fluid from the inlet to the outlet , wherein the baffle includes an end portion configured with a shape that substantially corresponds to the shape of the at least one inwardly contoured surface so as to mate or fit together with the same, and wherein the flow conditioning portion also has at least one slot (14c 1 , 14c 2 , 14c 3 , 14c 4 ; 148a 148b, 148c, 148d) configured to receive and engage the end portion of the baffle , wherein the at least one slot (14c 1 , 14c 2 , 14c 3 , 14c 4 ; 148a 148b, 148c, 148d) is formed in the at least one inwardly contoured surface .
A computer implemented method for providing vehicle route guidance, the method comprising: receiving routing data for directing a user from an origin location to a destination location, the routing data including a route; determining a set of road bins through which the route passes, wherein each road bin represents: a geofence comprising at least a portion of a road segment, a heading associated with the road bin, and points of interest, POls, visible from within the geofence when the user travels at the heading; identifying , based on the determined set of road bins, a set of POIs that are visible along the route; and as the user moves along the route: receiving location data from a user device , the location data indicating the user's current location and heading; determining the road bin associated with the user's current location and heading, and determining the visible POIs associated with the road bin; and transmitting routing instructions related to the visible POIs to the user device, the routing instructions including information about the route in relation to the POIs that are visible at the user's current location and heading. receiving routing data for directing a user from an origin location to a destination location, the routing data including a route; determining a set of road bins through which the route passes, wherein each road bin represents: a geofence comprising at least a portion of a road segment, a heading associated with the road bin, and points of interest, POls, visible from within the geofence when the user travels at the heading; identifying , based on the determined set of road bins, a set of POIs that are visible along the route; and as the user moves along the route: receiving location data from a user device , the location data indicating the user's current location and heading; determining the road bin associated with the user's current location and heading, and determining the visible POIs associated with the road bin; and transmitting routing instructions related to the visible POIs to the user device, the routing instructions including information about the route in relation to the POIs that are visible at the user's current location and heading. receiving location data from a user device , the location data indicating the user's current location and heading; determining the road bin associated with the user's current location and heading, and determining the visible POIs associated with the road bin; and transmitting routing instructions related to the visible POIs to the user device, the routing instructions including information about the route in relation to the POIs that are visible at the user's current location and heading.
A surgical implant , comprising: an implantable body ; an adjustable filament loop coupled to the implantable body, the adjustable filament loop having at least one adjustable limb (52; 54) extending therefrom, the at least one adjustable limb being configured to adjust a size of the adjustable filament loop when tension is applied thereto; and a shuttle suture removably coupled to the implantable body, wherein the surgical implant is characterised by the shuttle suture having at least a portion thereof that is hollow, wherein the at least one adjustable limb extends from the adjustable filament loop, into the hollow portion of the shuttle suture, and exits the shuttle suture at a location that is more remote from the implantable body than a location at which the adjustable limb entered the shuttle suture. an implantable body ; an adjustable filament loop coupled to the implantable body, the adjustable filament loop having at least one adjustable limb (52; 54) extending therefrom, the at least one adjustable limb being configured to adjust a size of the adjustable filament loop when tension is applied thereto; and a shuttle suture removably coupled to the implantable body, wherein the surgical implant is characterised by the shuttle suture having at least a portion thereof that is hollow, wherein the at least one adjustable limb extends from the adjustable filament loop, into the hollow portion of the shuttle suture, and exits the shuttle suture at a location that is more remote from the implantable body than a location at which the adjustable limb entered the shuttle suture.
A chimeric molecule comprising at least one gene editing agent comprising a CRISPR/Cas molecule, or a Cas9 nuclease, and at least one guide RNA, fused, complexed or linked to one or more anionic molecules, wherein the anionic molecule is a negatively charged fluorescent protein, for use in the treatment of deafness or disorders thereof associated with a Pmca2 genetic mutation in a patient in need thereof, wherein the at least one guide RNA targets a genetic locus comprising Pmca2.
Sepiapterin, or a pharmaceutically acceptable salt or co-crystal thereof, for use in a method of treating a subject exposed to radiation, the method comprising administering an effective amount of said sepiapterin, salt, or co-crystal to the subject, wherein: (a) the administering reduces or inhibits tissue and/or organ damage in the subject; (b) the administering reduces or inhibits cardiac and/or lung toxicity in the subject; (c) the administering decreases gastrointestinal, cardiac, and/or lung endothelial cell death in the subject; or (d) the administering reduces radiation-induced inflammation in gastrointestinal, cardiac, and/or lung epithelial cells in the subject. the method comprising administering an effective amount of said sepiapterin, salt, or co-crystal to the subject, wherein: (a) the administering reduces or inhibits tissue and/or organ damage in the subject; (b) the administering reduces or inhibits cardiac and/or lung toxicity in the subject; (c) the administering decreases gastrointestinal, cardiac, and/or lung endothelial cell death in the subject; or (d) the administering reduces radiation-induced inflammation in gastrointestinal, cardiac, and/or lung epithelial cells in the subject. (a) the administering reduces or inhibits tissue and/or organ damage in the subject; (b) the administering reduces or inhibits cardiac and/or lung toxicity in the subject; (c) the administering decreases gastrointestinal, cardiac, and/or lung endothelial cell death in the subject; or (d) the administering reduces radiation-induced inflammation in gastrointestinal, cardiac, and/or lung epithelial cells in the subject.
A method for operating a printing press , wherein the printing press has at least one first printing assembly and at least one dryer unit , and wherein the at least one dryer unit has at least one first dryer with at least one first energy output device (302; 317) and wherein in a first deactivation process the at least one first energy output device (302; 317) moves along an actuating distance in an actuating direction (S) from an active position by at least 5 mm to a threading position and held there and wherein the actuating distance extends in a continuously linear manner in and/or opposite to an actuating direction (S) over at least 75% of its entire length and wherein in a threading process taking place subsequently at least one web-type printing substrate is threaded by means of at least one threading means along a transport path provided for the printing substrate through an active region of the at least one energy output device (302; 317) and wherein in a second deactivation process the at least one first energy output device (302; 317) is moved along the actuating distance in a continuously linear manner in and/or opposite to an actuating direction (S) over at least 75% of its entire length from the active position by at least 450 mm in an access position, access position different from the threading position and is held there and wherein in a first maintenance process taking place subsequently at least one maintenance task is performed on the at least first energy output device (302; 317).
Bearing which has an axis of rotation and can be interposed between a first structure and a second structure , the first and second structures being rotatable with respect one another about the axis of the bearing, this bearing comprising: - a first and a second bearing race (130, 150...), wherein one part of the second bearing race extends around the first, radially with respect to said axis , - and multiple series of rolling elements interposed between the first and second bearing races, in annular fashion about said axis , said multiple series of rolling elements comprising at least three annular series, of which at least two are situated, with respect to said axis , on different radius (R1, R2), and being arranged in at least three rows staggered along said axis, and the rolling elements of the one or more intermediate rows of said at least three rows of rolling elements staggered along said axis of rotation of the bearing being preloaded in a plane perpendicular to said axis of rotation, the two end rows of said at least three rows of rolling elements staggered along said axis of rotation of the bearing each comprise a series of rolling elements with point contacts characterized in that the rolling elements of the one or more intermediate rows of said at least three rows of rolling elements comprise rolling elements with point contacts . - a first and a second bearing race (130, 150...), wherein one part of the second bearing race extends around the first, radially with respect to said axis , - and multiple series of rolling elements interposed between the first and second bearing races, in annular fashion about said axis ,
Taxane compounds having the structure represented by the following general formula I: wherein, R 1 is benzoyl, t -butyloxycarbonyl, or N,N'-dimethylcarbamoyl; R 2 is phenyl, R 3 is -OMe, -H 3 , -OCON(CH 3 ) 2 , or -OCOSC 2 H 5 ; R 4 is-OMe, -OCOOCH 3 , -OCON(CH 3 ) 2 , or -OCOSC 2 H 5 . R 1 is benzoyl, t -butyloxycarbonyl, or N,N'-dimethylcarbamoyl; R 2 is phenyl, R 3 is -OMe, -H 3 , -OCON(CH 3 ) 2 , or -OCOSC 2 H 5 ; R 4 is-OMe, -OCOOCH 3 , -OCON(CH 3 ) 2 , or -OCOSC 2 H 5 .