mhurhangee/patent-ind-claim-en huggingface dataset:
A Poly (ADP-ribose) polymerase (PARP) 1/2 inhibitor for use in a method of treating a lymphoproliferative disorder in a mammalian subject, the method comprising: a) measuring LIM domain only 2 (LMO2) in lymphocytes isolated from a mammalian subject suffering from a lymphoproliferative disorder ; and b) administering an effective amount of Poly (ADP-ribose) polymerase (PARP) 1/2 inhibitor to the mammalian subject where an increase in the RNA or protein level of LMO2 compared to LMO2 RNA or protein levels in a mammal not suffering from a lymphoproliferative disorder is detected in the lymphocytes, wherein the lymphoproliferative disorder is diffuse large B cell lymphoma (DLBCL), germinal center B cell-like diffuse large B cell lymphoma (GCB), activated B cell-like diffuse large B cell lymphoma (ABC), primary mediastinal B cell lymphoma (PMBL), double-hit lymphoma (DHL), follicular lymphoma (FL), Burkitt lymphoma (BL), mantle cell lymphoma (MCL), small cell lymphocytic lymphoma (SLL), mucosa-associated lymphoid tissue lymphoma (MALT), splenic marginal zone lymphoma (SMZL), nodal marginal zone lymphoma (NMZ), lymphoplasmacytic lymphoma (LPL), post-transplant lymphoproliferative disorder (PTLD), lymphoblastic lymphoma (LBL), double hit diffuse large B cell lymphoma, or multiple myeloma, in which cases the lymphocytes of step (a) are B-lymphocytes, or wherein the lymphoproliferative disorder is B- or T-cell acute lymphoblastic leukemia (B-ALL or T-ALL), in which cases the lymphocytes of step (a) are B-lymphocytes or T-lymphocytes. a) measuring LIM domain only 2 (LMO2) in lymphocytes isolated from a mammalian subject suffering from a lymphoproliferative disorder ; and b) administering an effective amount of Poly (ADP-ribose) polymerase (PARP) 1/2 inhibitor to the mammalian subject where an increase in the RNA or protein level of LMO2 compared to LMO2 RNA or protein levels in a mammal not suffering from a lymphoproliferative disorder is detected in the lymphocytes, wherein the lymphoproliferative disorder is diffuse large B cell lymphoma (DLBCL), germinal center B cell-like diffuse large B cell lymphoma (GCB), activated B cell-like diffuse large B cell lymphoma (ABC), primary mediastinal B cell lymphoma (PMBL), double-hit lymphoma (DHL), follicular lymphoma (FL), Burkitt lymphoma (BL), mantle cell lymphoma (MCL), small cell lymphocytic lymphoma (SLL), mucosa-associated lymphoid tissue lymphoma (MALT), splenic marginal zone lymphoma (SMZL), nodal marginal zone lymphoma (NMZ), lymphoplasmacytic lymphoma (LPL), post-transplant lymphoproliferative disorder (PTLD), lymphoblastic lymphoma (LBL), double hit diffuse large B cell lymphoma, or multiple myeloma, in which cases the lymphocytes of step (a) are B-lymphocytes, or wherein the lymphoproliferative disorder is B- or T-cell acute lymphoblastic leukemia (B-ALL or T-ALL), in which cases the lymphocytes of step (a) are B-lymphocytes or T-lymphocytes.
A method of acidizing a formation penetrated by a wellbore comprising the steps of: a. injecting into the wellbore at a pressure below formation fracturing pressure a treatment fluid comprising a gelling fluid comprising a gelling agent and a hydrophobically-modified associative polymer, and an aqueous acid; and b. allowing the treatment fluid to acidize the formation, characterized in that the hydrophobically-modified associative polymer comprises at least one water-insoluble part selected from the group consisting of straight or branched alkyl or alkylaryl alcohol esters of acrylic or methacrylic acid. a. injecting into the wellbore at a pressure below formation fracturing pressure a treatment fluid comprising a gelling fluid comprising a gelling agent and a hydrophobically-modified associative polymer, and an aqueous acid; and b. allowing the treatment fluid to acidize the formation,
A sealing test device for checking out the sealing of a cork stopper (R), which cork stopper (R) comprises a body defining a central part and two ends , the device comprising: • a cork stopper receiving chamber ; • a chamber partitioning mechanism which divides the chamber in two compartments , the mechanism comprising: • an adjustable insulator to said central part of the cork stopper (R), wherein the insulator is configured for, upon actuation, sealing hermetically the central part of the cork stopper body in relation to the outside environment, and simultaneously for arranging each end of the stopper (R) in one of said compartments , • an insulator actuation member , configured for, upon actuation, arranging the insulator on the central part of the cork stopper body; • at least one chamber compartment closing block arranged for, in operation, closing and hermetically isolating a respective compartment in relation to the outside environment and, together with said insulator , for isolating hermetically the compartments from each other; • at least one test fluid inlet arranged in at least one closing block ; • at least one detection member arranged for detecting head loss or for detecting test fluid in at least one of the compartments ; and • at least one test fluid source connected to at least one test fluid inlet . • a cork stopper receiving chamber ; • a chamber partitioning mechanism which divides the chamber in two compartments , the mechanism comprising: • an adjustable insulator to said central part of the cork stopper (R), wherein the insulator is configured for, upon actuation, sealing hermetically the central part of the cork stopper body in relation to the outside environment, and simultaneously for arranging each end of the stopper (R) in one of said compartments , • an insulator actuation member , configured for, upon actuation, arranging the insulator on the central part of the cork stopper body; • an adjustable insulator to said central part of the cork stopper (R), wherein the insulator is configured for, upon actuation, sealing hermetically the central part of the cork stopper body in relation to the outside environment, and simultaneously for arranging each end of the stopper (R) in one of said compartments , • an insulator actuation member , configured for, upon actuation, arranging the insulator on the central part of the cork stopper body; • at least one chamber compartment closing block arranged for, in operation, closing and hermetically isolating a respective compartment in relation to the outside environment and, together with said insulator , for isolating hermetically the compartments from each other; • at least one test fluid inlet arranged in at least one closing block ; • at least one detection member arranged for detecting head loss or for detecting test fluid in at least one of the compartments ; and • at least one test fluid source connected to at least one test fluid inlet .
An assembly kit (1a, 1b; 101a, 10b) for a vertical awning or roller blind comprising at least one reel shaft and a curtain received thereupon which can be wound up and down, and further a box enclosing the reel shaft comprising a bottom side through-opening for the curtain , with the box being designed as a top piece for being placed on a door frame or window frame (12; 112) comprising a casing (3, 4, 5, 6, 19, 20, 21;103, 106, 117, 119) coaxially extending around the reel shaft, and end face covers (2, 22; 102), and further comprising at least one base system (1a; 101a) with the at least one reel shaft and the associated blind , and a reel shaft carrier (2, 3, 4, 6; 102, 104, 106), with the reel shaft carrier (2, 3, 4, 6; 102, 104, 106) comprising two end face bearing plates (2; 102) for the reel shaft and a number of bridge elements (3, 4, 6; 104, 106) firmly connecting the two bearing plates and spanning the reel shaft, and with an additional housing (1b; 101b) at least partly forming the casing (3, 4, 5, 6, 19, 20, 21; 103, 106, 117,119) extending coaxially around the reel shaft, which additional housing (1b; 101b) at the base system (1a; 101a) attached thereto complements the reel shaft carrier (2, 3, 4, 6;102, 104) to form the box housing the reel shaft, with the base system (1a; 101a) attached to the additional housing (1b; 101b) being movable relative to the additional housing (1b; 101b) in a longitudinal direction relative to the reel shaft axis.
Conductor terminal having a housing made of insulating material, a busbar , a clamping spring and an actuating lever which is accommodated pivotably in the housing made of insulating material via a pivoting region and can be pivoted between an open position and a closed position, the clamping spring having an actuating limb which is deflected via a spring driver of the actuating lever at least in the open position, the actuating lever being supported in the open position at least at a first bearing point , the insulating housing having an intermediate wall , on one side of which the first bearing point is formed and along the opposite side of which the clamping spring runs, characterized in that the intermediate wall is supported and counter-supported on the clamping spring with respect to the bearing force applied to the intermediate wall by the actuating lever at the first bearing point .
Floating-caliper brake, comprising a brake caliper floatingly mounted on a support structure of the floating-caliper brake , on which brake caliper a first brake pad and a pressing device are arranged, wherein a second brake pad being arranged on the pressing device and the pressing device moving the second brake pad toward the first brake pad in order to actuate the floating-caliper brake and moving the second brake pad away from the first brake pad in order to release the floating-caliper brake , wherein a lifting part is hinged to the brake caliper at a hinge point , characterized in that the lifting part is supported on the support structure at a contact point at least partly at releasing the floating-caliper brake , and in that a lift drive is provided which rotates the lifting part about the hinge point such that a support for the lifting part is produced at the contact point , whereby the hinge point and the brake caliper are moved.
An electric power steering system configured to drive a motor based on an assist map in which a current command value (Irefl) in accordance with steering torque (Ts) and a vehicle speed (Vs) is defined and configured to perform assist control on a steering system of a vehicle, the electric power steering system comprising: a current command value calculating unit configured to output a current command value (Irefa) in accordance with the steering torque (Ts) and the vehicle speed (Vs), based on the assist map, wherein the current command value calculating unit includes a vibration component reducing section configured to reduce a vibration component resulting from vibrations for warning that have been transmitted to a steering wheel , the vibration component being included in the steering torque (Ts), characterized in that the current command value calculating unit multiplies a difference value between the steering torque (Ts) and output from the vibration component reducing section by a predetermined gain factor (K), and adds a resultant value to the current command value (Irefa). a current command value calculating unit configured to output a current command value (Irefa) in accordance with the steering torque (Ts) and the vehicle speed (Vs), based on the assist map, wherein the current command value calculating unit includes a vibration component reducing section configured to reduce a vibration component resulting from vibrations for warning that have been transmitted to a steering wheel , the vibration component being included in the steering torque (Ts), characterized in that the current command value calculating unit multiplies a difference value between the steering torque (Ts) and output from the vibration component reducing section by a predetermined gain factor (K), and adds a resultant value to the current command value (Irefa).
An assembly, comprising: a stent lattice having a plurality of pivotably connected struts and one or more drive screws rotatably coupled to the struts, wherein rotating the one or more drive screws in a first direction relative to the struts radially expands the stent lattice, and wherein rotating the one or more drive screws in a second direction relative to the struts radially contracts the stent lattice; and a delivery system including one or more motors, one or more drive wires coupled to the one or more motors, and a memory, wherein the one or more drive wires are coupled to the one or more drive screws of the stent lattice, wherein the one or more motors are configured to rotate the one or more drive wires and the one or more drive screws to expand and contract the stent lattice, wherein the memory is configured for storing one or more characteristics of the one or more motors, the one or more drive wires, or the stent lattice, wherein the one or more characteristics stored in the memory of the delivery system include first characteristics corresponding to expanding the stent lattice outside a patient's body, and wherein the delivery system is further configured to display second characteristics corresponding to expanding the stent lattice inside the patient's body and to compare the second characteristics to the first characteristics. a stent lattice having a plurality of pivotably connected struts and one or more drive screws rotatably coupled to the struts, wherein rotating the one or more drive screws in a first direction relative to the struts radially expands the stent lattice, and wherein rotating the one or more drive screws in a second direction relative to the struts radially contracts the stent lattice; and a delivery system including one or more motors, one or more drive wires coupled to the one or more motors, and a memory, wherein the one or more drive wires are coupled to the one or more drive screws of the stent lattice, wherein the one or more motors are configured to rotate the one or more drive wires and the one or more drive screws to expand and contract the stent lattice, wherein the memory is configured for storing one or more characteristics of the one or more motors, the one or more drive wires, or the stent lattice, wherein the one or more characteristics stored in the memory of the delivery system include first characteristics corresponding to expanding the stent lattice outside a patient's body, and wherein the delivery system is further configured to display second characteristics corresponding to expanding the stent lattice inside the patient's body and to compare the second characteristics to the first characteristics.
An air conditioner comprising: a case having an inner space; a fan disposed inside the case ; a frame coupled to a front portion of the case ; a front plate coupled to the frame to be movable in a front-rear direction, wherein a suction port is formed between the front plate and the frame ; a discharge flow path that air blown by the fan flows and that is spaced rearward from the suction port ; a discharge grille disposed downstream of the discharge flow path and comprising a guide inclined forward as the guide goes away from the discharge flow path , wherein the guide is configured in plural and the plurality of guides are spaced apart from each other in the front-rear direction, and wherein the guide comprises: a guide body positioned inward further than an outer surface of the discharge grille ; and a guide end portion positioned outward further than the outer surface of the discharge grille . a case having an inner space; a fan disposed inside the case ; a frame coupled to a front portion of the case ; a front plate coupled to the frame to be movable in a front-rear direction, wherein a suction port is formed between the front plate and the frame ; a discharge flow path that air blown by the fan flows and that is spaced rearward from the suction port ; a discharge grille disposed downstream of the discharge flow path and comprising a guide inclined forward as the guide goes away from the discharge flow path , wherein the guide is configured in plural and the plurality of guides are spaced apart from each other in the front-rear direction, and wherein the guide comprises: a guide body positioned inward further than an outer surface of the discharge grille ; and a guide end portion positioned outward further than the outer surface of the discharge grille . a guide body positioned inward further than an outer surface of the discharge grille ; and a guide end portion positioned outward further than the outer surface of the discharge grille .
A transdermal absorption preparation comprising: a support; and an adhesive layer formed on at least one side of the support, wherein the adhesive layer contains 2.5% to 8% by mass phosphatidylcholine, 25.0% to 30.0%by mass of an adhesive component, 40.0% to 75.0%by mass of a lipophilic component and 8.5 to 12.0 parts by mass carnitine with respect to phosphatidylcholine mass taken as 100 parts, wherein the entire mass of the adhesive layer is 100% by mass, wherein the adhesive component is a styrene-based block copolymer selected from styrene-butadiene block copolymers and hydrogenated styrene-butadiene block copolymers having a weight average molecular weight of 10,000 to 5,500,000, styrene-isoprene block copolymers and hydrogenated styrene-isoprene block copolymers having a weight average molecular weight of 10,000 to 5,500,000 and styrene-isoprene-styrene block copolymers and hydrogenated styrene-isoprene-styrene block copolymers having a weight average molecular weight of 18,000 to 5,500,000, and wherein the weight average molecular weight is measured by gel filtration chromatography. wherein the adhesive layer contains 2.5% to 8% by mass phosphatidylcholine, 25.0% to 30.0%by mass of an adhesive component, 40.0% to 75.0%by mass of a lipophilic component and 8.5 to 12.0 parts by mass carnitine with respect to phosphatidylcholine mass taken as 100 parts, wherein the entire mass of the adhesive layer is 100% by mass, wherein the adhesive component is a styrene-based block copolymer selected from styrene-butadiene block copolymers and hydrogenated styrene-butadiene block copolymers having a weight average molecular weight of 10,000 to 5,500,000, styrene-isoprene block copolymers and hydrogenated styrene-isoprene block copolymers having a weight average molecular weight of 10,000 to 5,500,000 and styrene-isoprene-styrene block copolymers and hydrogenated styrene-isoprene-styrene block copolymers having a weight average molecular weight of 18,000 to 5,500,000, and wherein the weight average molecular weight is measured by gel filtration chromatography.
A stopper for a tin for liquids, in particular for paints; wherein said stopper is made in a single piece and is made of a polymeric material; said stopper comprises a tubular abutment , which is configured to be coupled, in use, to the body of a tin , and a diaphragm configured to be torn out, in use, at the moment of the first opening; said diaphragm having an incision (k) which extends along a first side perimeter (p1) and reduces locally the depth of the diaphragm ; said diaphragm having one or more lines of weakness (20; 20I, 20II) which reduce locally the depth of the diaphragm and delimit laterally a removable portion : wherein, a part of said incision (k) coincides, namely is at least incident with a respective part of one of the lines of weakness (20; 20I, 20II); wherein said removable portion extends along a tear path (t) which comprises: a straight section (t1); a connecting section (t2); and a semi-circular section (t3); wherein, the connecting section (t2) is interposed between and connects the straight section (t1) and the semi-circular section (t3) ; wherein, the first side perimeter (p1) of the diaphragm is a circumference and has a first radius (R1) which extends from a centre (O) crossed by a central axis (X'); in particular, said semi-circular section (t3) is coaxial to said central axis (X'); wherein the diaphragm has a central portion which is integral, namely the central portion has no depth reductions; said central portion is delimited by a second side perimeter (p2), which is circular and is coaxial to said central axis (X') and has a second radius (R4); in particular, said second radius (R4) has a length that is at least 40% of the length of said first radius (R1); wherein, the tear path (t) has a starting area (t0) at which the tear of the removable portion is triggered; wherein, said tear path (t) is entirely made on a plane surface; said stopper being characterised in that : the diaphragm is shaped so as to form at least a housing ; wherein, said housing is made within said central portion ; the housing is delimited by a bottom wall and a side wall ; wherein, the diaphragm further comprises an annular wall which extends radially around the side wall between the first side perimeter (p1) and the second side perimeter (p2) ; the starting area (t0) being radially arranged outside the central portion .
A computer-implemented method performed by a software-controlled communication device associated with a subscription telephone number in a telephone network , said method comprising: operating a monitoring process to detect an incoming verification call and determine an originating telephone number (ORIGIN#) of the incoming verification call, or an identifier (ID2) transmitted by the incoming verification call, by identifying the incoming verification call as the first incoming call that originates from a telephone number that matches a group of telephone numbers known by said communication device, said incoming verification call being initiated at a server system to verify an unconfirmed telephone number (MY#) by placing, in response to an initial verification request (VR1) including the unconfirmed telephone number, the verification call to the unconfirmed telephone number (MY#) from a calling telephone number (CALLER#); and transmitting, when the monitoring process detects the incoming verification call, a second verification request (VR2) to the server system , the second verification request (VR2) including the originating telephone number (ORIGIN#) of the incoming verification call or the identifier (ID2), thereby allowing the server system to verify that the unconfirmed telephone number (MY#) is a subscription telephone number assigned to the communication device by comparing the originating telephone number (ORIGIN#) with the calling telephone number (CALLER#) or by validating the identifier (ID2). operating a monitoring process to detect an incoming verification call and determine an originating telephone number (ORIGIN#) of the incoming verification call, or an identifier (ID2) transmitted by the incoming verification call, by identifying the incoming verification call as the first incoming call that originates from a telephone number that matches a group of telephone numbers known by said communication device, said incoming verification call being initiated at a server system to verify an unconfirmed telephone number (MY#) by placing, in response to an initial verification request (VR1) including the unconfirmed telephone number, the verification call to the unconfirmed telephone number (MY#) from a calling telephone number (CALLER#); and transmitting, when the monitoring process detects the incoming verification call, a second verification request (VR2) to the server system , the second verification request (VR2) including the originating telephone number (ORIGIN#) of the incoming verification call or the identifier (ID2), thereby allowing the server system to verify that the unconfirmed telephone number (MY#) is a subscription telephone number assigned to the communication device by comparing the originating telephone number (ORIGIN#) with the calling telephone number (CALLER#) or by validating the identifier (ID2).