mhurhangee/patent-ind-claim-en huggingface dataset:
A polymerization process comprising the steps of: i) agitating a mixture comprising: 25 weight percent or more of a carrier liquid, a surfactant, and one or more first monomers to form micelles of the one or more monomers in the carrier liquid, wherein the one or more first monomers includes one or more 1,1-disubstituted alkenes, wherein the 1,1-disubstituted alkene includes a central carbon atom doubly bonded to a second carbon atom and further bonded to two carbonyl groups; ii) reacting an activator with at least one of the first monomers in the micelle for initiating the anionic polymerization of the one or more first monomers; and iii) anionically polymerizing the one or more first monomers to a number average molecular weight of 700 g/mole or more wherein number average molecular weight is determined by a gel permeation chromatography, using the method disclosed herein; iv) adding one or more second monomers to the emulsion following the step of anionically polymerizing the one or more first monomers, wherein the one or more second monomers differ from the one or more first monomers in composition or includes a different monomer; and v) anionically polymerizing the one or more second monomers. i) agitating a mixture comprising: 25 weight percent or more of a carrier liquid, a surfactant, and one or more first monomers to form micelles of the one or more monomers in the carrier liquid, wherein the one or more first monomers includes one or more 1,1-disubstituted alkenes, wherein the 1,1-disubstituted alkene includes a central carbon atom doubly bonded to a second carbon atom and further bonded to two carbonyl groups; ii) reacting an activator with at least one of the first monomers in the micelle for initiating the anionic polymerization of the one or more first monomers; and iii) anionically polymerizing the one or more first monomers to a number average molecular weight of 700 g/mole or more wherein number average molecular weight is determined by a gel permeation chromatography, using the method disclosed herein; iv) adding one or more second monomers to the emulsion following the step of anionically polymerizing the one or more first monomers, wherein the one or more second monomers differ from the one or more first monomers in composition or includes a different monomer; and v) anionically polymerizing the one or more second monomers.
An inkjet ink comprising: a metal complex dye; a polyoxyethylene based compound of at least one type selected from a group consisting of polyoxyalkylene glycols and polyoxyalkylene alkyl ethers and with which a number average molecular weight Mn is not less than 200; a tackifier of at least one type selected from a group consisting of terpene phenol resins and rosin esters and with which a hydroxyl value is not less than 30 mgKOH/g and not more than 70 mgKOH/g; a first solvent of at least one type selected from 2-butanone, acetone, 2-pentanone, 3-pentanone, 3-methyl-2-butanone, 2-methyl-4-pentanone, 2,6-dimethyl-4-heptanone, cyclohexanone, 4-hydroxy-4-methyl-pentan-2-one, 1,4-dioxane, 1,1-dimethyldiethyl ether, 2-ethoxyethanol, 2-butoxyethanol, 1-methoxy-2-propanol, 2-(2-ethoxyethoxy)ethanol, 2-(2-butoxyethoxy)ethanol, Ethyl acetate, methyl acetate, n-butyl acetate, sec-butyl acetate, pentyl ethanoate, propyl acetate, isopropyl ethanoate, and 2-(2-butoxyethoxy)ethyl acetate; and a second solvent being an alcohol including at least an alcohol with 1 to 3 carbon atoms selected from methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, and 2-butanol. a metal complex dye; a polyoxyethylene based compound of at least one type selected from a group consisting of polyoxyalkylene glycols and polyoxyalkylene alkyl ethers and with which a number average molecular weight Mn is not less than 200; a tackifier of at least one type selected from a group consisting of terpene phenol resins and rosin esters and with which a hydroxyl value is not less than 30 mgKOH/g and not more than 70 mgKOH/g; a first solvent of at least one type selected from 2-butanone, acetone, 2-pentanone, 3-pentanone, 3-methyl-2-butanone, 2-methyl-4-pentanone, 2,6-dimethyl-4-heptanone, cyclohexanone, 4-hydroxy-4-methyl-pentan-2-one, 1,4-dioxane, 1,1-dimethyldiethyl ether, 2-ethoxyethanol, 2-butoxyethanol, 1-methoxy-2-propanol, 2-(2-ethoxyethoxy)ethanol, 2-(2-butoxyethoxy)ethanol, Ethyl acetate, methyl acetate, n-butyl acetate, sec-butyl acetate, pentyl ethanoate, propyl acetate, isopropyl ethanoate, and 2-(2-butoxyethoxy)ethyl acetate; and a second solvent being an alcohol including at least an alcohol with 1 to 3 carbon atoms selected from methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, and 2-butanol.
A therapeutically effective amount of a compound being a first active agent selected from a compound of formula (I) and (II): or an enantiomer thereof, a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable hydrate, a pharmaceutically acceptable solvate, a pharmaceutically acceptable clathrate, or a pharmaceutically acceptable polymorph thereof, for use in a method of treating cystic fibrosis, wherein the method further comprises the administration to a patient in need of a therapeutically effective amount of a cystic fibrosis transmembrane conductance regulator potentiator, a therapeutically effective amount of a cystic fibrosis transmembrane conductance regulator corrector, or a combination thereof, wherein the cystic fibrosis transmembrane conductance regulator potentiator is ivacaftor, and wherein the cystic fibrosis transmembrane conductance regulator corrector is lumacaftor. or an enantiomer thereof, a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable hydrate, a pharmaceutically acceptable solvate, a pharmaceutically acceptable clathrate, or a pharmaceutically acceptable polymorph thereof, for use in a method of treating cystic fibrosis, wherein the method further comprises the administration to a patient in need of a therapeutically effective amount of a cystic fibrosis transmembrane conductance regulator potentiator, a therapeutically effective amount of a cystic fibrosis transmembrane conductance regulator corrector, or a combination thereof, wherein the cystic fibrosis transmembrane conductance regulator potentiator is ivacaftor, and wherein the cystic fibrosis transmembrane conductance regulator corrector is lumacaftor.
A method of encapsulating a nucleic acid in a lipid nanoparticle host to provide an encapsulated nucleic acid nanoparticle, the method comprising: providing two nucleic acid streams, each of the two nucleic acid streams comprising a mixture of a nucleic acid in a first aqueous solution, and having a combined linear velocity of greater than or equal to 1.5 meter/second; providing one lipid stream, the one lipid stream comprising a mixture of one or more lipids in an organic solvent, and having a linear velocity of greater than or equal to 1.5 meter/second; mixing the one lipid stream with the two nucleic acid streams at a first intersection point configured as a cross connector, wherein the two nucleic acid streams enter the cross connector from opposing directions at 180° relative to each other, and the one lipid stream enters the cross connector at 90° relative to the two nucleic acid streams to provide a first mixed stream; flowing the first mixed stream in a first direction out of the cross connector in substantially the same direction as the one lipid stream and 90° relative to the two nucleic acids; and mixing the components of the first mixed stream to provide a first outlet solution comprising the encapsulated nucleic acid nanoparticle; wherein the first aqueous solution and the organic solvent are miscible, one of the first aqueous solution or the organic solvent contains a buffer, and the concentration of the organic solvent in the first outlet solution is less than 33%. providing two nucleic acid streams, each of the two nucleic acid streams comprising a mixture of a nucleic acid in a first aqueous solution, and having a combined linear velocity of greater than or equal to 1.5 meter/second; providing one lipid stream, the one lipid stream comprising a mixture of one or more lipids in an organic solvent, and having a linear velocity of greater than or equal to 1.5 meter/second; mixing the one lipid stream with the two nucleic acid streams at a first intersection point configured as a cross connector, wherein the two nucleic acid streams enter the cross connector from opposing directions at 180° relative to each other, and the one lipid stream enters the cross connector at 90° relative to the two nucleic acid streams to provide a first mixed stream; flowing the first mixed stream in a first direction out of the cross connector in substantially the same direction as the one lipid stream and 90° relative to the two nucleic acids; and mixing the components of the first mixed stream to provide a first outlet solution comprising the encapsulated nucleic acid nanoparticle; wherein the first aqueous solution and the organic solvent are miscible, one of the first aqueous solution or the organic solvent contains a buffer, and the concentration of the organic solvent in the first outlet solution is less than 33%.
A method comprising: applying a first liquid polymer to a first surface of a substrate , the substrate having a second surface that is opposite the first surface; illuminating the first liquid polymer with light to change at least one property of the first liquid polymer and obtain a modified polymer attached to the first surface of the substrate applying a second liquid polymer to at least a portion of a surface of a Fresnel structure ; applying the second surface of the substrate to an outer surface of the second liquid polymer applied to the Fresnel structure to obtain a stacked Fresnel structure ; and illuminating the stacked Fresnel structure with light to obtain an immersed Fresnel structure . applying a first liquid polymer to a first surface of a substrate , the substrate having a second surface that is opposite the first surface; illuminating the first liquid polymer with light to change at least one property of the first liquid polymer and obtain a modified polymer attached to the first surface of the substrate applying a second liquid polymer to at least a portion of a surface of a Fresnel structure ; applying the second surface of the substrate to an outer surface of the second liquid polymer applied to the Fresnel structure to obtain a stacked Fresnel structure ; and illuminating the stacked Fresnel structure with light to obtain an immersed Fresnel structure .
Method for operating a heat exchanger , a heat transfer medium flowing through this heat exchanger on a primary side and entering the heat exchanger at a first temperature ( T 1 , T in W ) and exiting the heat exchanger at a second temperature ( T 2 , T out W ) , which heat exchanger, on a secondary side, emits a heat flow ( Q̇ ) to a secondary medium flowing through the heat exchanger in the case of heating or absorbs a heat flow ( Q̇ ) from the secondary medium in the case of cooling, which secondary medium enters the heat exchanger at a third temperature ( T 3 , T in L ) and exits the heat exchanger again at a fourth temperature ( T 4 , T out L ) , wherein the heat exchanger can transfer a maximum heat flow ( Q̇ max ) , wherein at least three of the four temperatures ( T 1 - T 4 , T in W , T out W , T in L , T out L ) are measured, characterized in that the respective degree of saturation Q . Q . max of the heat exchanger is determined from these measured temperatures and is used to control the operation of the heat exchanger , and in that the heat exchanger is part of an HVAC system , wherein the flow of the heat transfer medium on the primary side of the heat exchanger is limited when the degree of saturation Q . Q . max of the heat exchanger reaches a prespecified value, or the degree of saturation Q . Q . max of the heat exchanger is used for controlling the flow of the secondary medium, or the inflow temperature ( T 1 , T in W ) of the heat transfer medium is increased when the degree of saturation of the heat exchanger reaches a prespecified value.
Fire-resistant glass door for preventing the passage of fire and/or smoke from one room to another in the event of fire, comprising a fire-resistant pane unit , consisting of at least two glass panes spaced parallel from one another by means of an edge seal and at least one fire-resistant material arranged between the at least two glass panes , and a lock case arranged in a glass cutout of the fire-resistant pane unit , wherein the edge seal of the fire-resistant pane unit , at least in the region of the glass cutout of the fire-resistant pane unit intended for the lock case , is at least partially recessed relative to the end face of at least the outer two glass panes of the fire-resistant pane unit , and the lock case has at least two recesses and/or depressions spaced parallel from one another on at least one of its outer sides facing toward the fire-resistant pane unit when the lock case is arranged in the glass cutout of the fire-resistant pane unit , in which recesses and/or depressions the at least outer two glass panes of the fire-resistant pane unit are form-fittingly and/or force-fittingly received when the lock case is arranged in the glass cutout of the fire-resistant pane unit . comprising a fire-resistant pane unit , consisting of at least two glass panes spaced parallel from one another by means of an edge seal and at least one fire-resistant material arranged between the at least two glass panes , and a lock case arranged in a glass cutout of the fire-resistant pane unit , wherein the edge seal of the fire-resistant pane unit , at least in the region of the glass cutout of the fire-resistant pane unit intended for the lock case , is at least partially recessed relative to the end face of at least the outer two glass panes of the fire-resistant pane unit , and the lock case has at least two recesses and/or depressions spaced parallel from one another on at least one of its outer sides facing toward the fire-resistant pane unit when the lock case is arranged in the glass cutout of the fire-resistant pane unit , in which recesses and/or depressions the at least outer two glass panes of the fire-resistant pane unit are form-fittingly and/or force-fittingly received when the lock case is arranged in the glass cutout of the fire-resistant pane unit .
A display device comprising: a display panel ; a plurality of vibro-acoustic elements coupled to the display panel and spaced apart from each other on the display panel , a bracket disposed below the display panel and including a bottom plate, wherein the plurality of vibro-acoustic elements produces audio frequencies in different frequency bands, respectively, wherein a plurality of receiving holes is defined through the bottom plate, the plurality of vibro-acoustic elements is disposed in the plurality of receiving holes , respectively, a portion of the bottom plate defining a receiving hole of the plurality of receiving holes is recessed from an upper surface toward a lower surface of the bottom plate, a vibration space is defined by the portion of the bottom plate recessed from the upper surface toward the lower surface of the bottom plate, and audio frequencies in different frequency bands, respectively, are produced from regions in which the plurality of vibro-acoustic elements is disposed. a display panel ; a plurality of vibro-acoustic elements coupled to the display panel and spaced apart from each other on the display panel , a bracket disposed below the display panel and including a bottom plate, wherein the plurality of vibro-acoustic elements produces audio frequencies in different frequency bands, respectively, wherein a plurality of receiving holes is defined through the bottom plate, the plurality of vibro-acoustic elements is disposed in the plurality of receiving holes , respectively, a portion of the bottom plate defining a receiving hole of the plurality of receiving holes is recessed from an upper surface toward a lower surface of the bottom plate, a vibration space is defined by the portion of the bottom plate recessed from the upper surface toward the lower surface of the bottom plate, and audio frequencies in different frequency bands, respectively, are produced from regions in which the plurality of vibro-acoustic elements is disposed.
A slider for a surgical instrument , the slider comprising: a slider body defining a longitudinal axis in a linear direction, the slider disposed to be movable in the linear direction (Z) relative to the surgical instrument ; and two holders disposed on the slider body for holding ends of a wire between the two holders to retain the wire in an annular shape, wherein at least a first holder of the two holders is provided with an insertion hole for inserting and passing the ends of the wire toward an outside from between the two holders , characterized in that the hole is penetrating the first holder in a direction perpendicular to the linear direction (Z). a slider body defining a longitudinal axis in a linear direction, the slider disposed to be movable in the linear direction (Z) relative to the surgical instrument ; and two holders disposed on the slider body for holding ends of a wire between the two holders to retain the wire in an annular shape, wherein at least a first holder of the two holders is provided with an insertion hole for inserting and passing the ends of the wire toward an outside from between the two holders , characterized in that the hole is penetrating the first holder in a direction perpendicular to the linear direction (Z).
An electrically conductive flexible frame comprising: an electrically conductive hollow cylindrical metallic tube having an outer surface, a circumference and a longitudinal axis (L-L), the metallic tube having a plurality of cuts along the longitudinal axis to form a flexible frame comprising a plurality of parallel conductive wires , each of the plurality of conductive wires being equally spaced apart circumferentially along the longitudinal axis of the tube by a gap to electrically isolate the plurality of wires; a first electrode mounted around the circumference of the flexible frame along the longitudinal axis of the tube and attached to a first wire of the plurality of wires; a second electrode mounted around the circumference of the flexible frame along the longitudinal axis of the tube at a predetermined distance from the first electrode and attached to a second wire of the plurality of wires, the second wire being adjacent to the first wire and not attached to the first wire; and a non-conductive thermoplastic layer secured to the outer surface of the flexible frame between the first and second electrodes, such that the thermoplastic layer circumferentially surrounds the plurality of wires to form an insulation layer between the first and second electrodes. an electrically conductive hollow cylindrical metallic tube having an outer surface, a circumference and a longitudinal axis (L-L), the metallic tube having a plurality of cuts along the longitudinal axis to form a flexible frame comprising a plurality of parallel conductive wires , each of the plurality of conductive wires being equally spaced apart circumferentially along the longitudinal axis of the tube by a gap to electrically isolate the plurality of wires; a first electrode mounted around the circumference of the flexible frame along the longitudinal axis of the tube and attached to a first wire of the plurality of wires; a second electrode mounted around the circumference of the flexible frame along the longitudinal axis of the tube at a predetermined distance from the first electrode and attached to a second wire of the plurality of wires, the second wire being adjacent to the first wire and not attached to the first wire; and a non-conductive thermoplastic layer secured to the outer surface of the flexible frame between the first and second electrodes, such that the thermoplastic layer circumferentially surrounds the plurality of wires to form an insulation layer between the first and second electrodes.
A harbour plant for storage, loading and unloading of hydrocarbon products at sea, comprising a number of units (11; 11') being mutually placed apart on the seabed, with at least three units forming a harbour site having a front surface along which a vessel can be moored, the units (11; 11') being placed independently at a given distance apart in sideways direction, the units (11; 11') forming a passage or passages for parts of the waves, and being configured to dampen a part of the incoming waves, while allowing other parts of the waves and current to pass through the passage or passages between neighbouring units , the sideways distances between two neighbouring units (11; 11') being governed by the frequency of the waves to be dampened and the frequencies of the waves allowed to pass in between the units (11; 11'), characterized in that the front surface of the middle unit of said three units (11; 11') is offset with a distance (R) relative to the front surfaces of the other two neighbouring units (11; 11') in a traverse direction with respect to the longitudinal direction of the plant , away from said incoming waves, and that said distance R is in the range of 2 to 60 meters.
A packet processing method, characterized by comprising: receiving, by a network node of an access network, a first packet sent by a user terminal, wherein the first packet is used to request an Internet Protocol IP address from a Dynamic Host Configuration Protocol, DHCP, server; obtaining, by the network node, a second packet, wherein the second packet comprises the first packet, information about a port, and a Media Access Control, MAC, address of the user terminal, the port is a port through which the network node receives the first packet, and the second packet is a packet except a DHCP packet, and the information about the port is outside of the first packet; and sending, by the network node, the second packet to a controller. receiving, by a network node of an access network, a first packet sent by a user terminal, wherein the first packet is used to request an Internet Protocol IP address from a Dynamic Host Configuration Protocol, DHCP, server; obtaining, by the network node, a second packet, wherein the second packet comprises the first packet, information about a port, and a Media Access Control, MAC, address of the user terminal, the port is a port through which the network node receives the first packet, and the second packet is a packet except a DHCP packet, and the information about the port is outside of the first packet; and sending, by the network node, the second packet to a controller.
Plain bearing , which has at least one inner sleeve which is surrounded by at least one damping layer which consists of at least one elastomer, an end face of the at least one plain bearing being visible, an indicator agent being introduced into at least one section of the elastomer forming the at least one damping layer , which, in the event of crack formation in the at least one damping layer , emerges at the end face in an optically detectable manner, characterized in that the indicator agent can be activated by heat development, so that the indicator agent emerges at the end face of the plain bearing by liquefaction.